## Sat Jan  4 12:52:19 2025
## emapper-2.1.12
## /data/home/zhuyingjie/miniforge3/envs/eggnog/bin/emapper.py -i /data/home/zhuyingjie/01_Project/01_metagenome/mangrove/mmseqs_cluster/PRJNA298972/SRR2844602/SRR2844602_p_cluster_rep_seq.fasta --output PRJNA298972_SRR2844602 --data_dir /data/software/eggnog_database -m diamond --sensmode fast --output_dir /data/home/zhuyingjie/01_Project/01_metagenome/mangrove/annotation --temp_dir /data/software/eggnog_database/temp --excel --dbmem --cpu 24
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
k59_1366536_2	1028800.RG540_CH13960	9.51e-10	57.4	2EVDQ@1|root,33NU5@2|Bacteria,1NQC2@1224|Proteobacteria,2UY7F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1018377_1	709032.Sulku_2304	1.87e-41	137.0	COG0254@1|root,COG0254@2|Bacteria,1PT0H@1224|Proteobacteria,42V2Z@68525|delta/epsilon subdivisions,2YQ19@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
k59_604687_1	709032.Sulku_1119	2.65e-75	226.0	COG2204@1|root,COG2204@2|Bacteria,1RHEG@1224|Proteobacteria,42UQT@68525|delta/epsilon subdivisions,2YPX9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_604687_2	709032.Sulku_1118	3.86e-10	59.3	COG0840@1|root,COG0840@2|Bacteria,1R5W9@1224|Proteobacteria,42PPM@68525|delta/epsilon subdivisions,2YN9B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	methyl-accepting chemotaxis protein	tlpD	-	-	-	-	-	-	-	-	-	-	-	CZB,MCPsignal
k59_1484990_1	246195.DNO_0405	5.2e-19	85.1	COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,1RNDS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	GO:0001676,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0003824,GO:0003989,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006417,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0017148,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032787,GO:0032991,GO:0034248,GO:0034249,GO:0042759,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:0097159,GO:1901363,GO:1901576,GO:1902494,GO:1990234,GO:2000112,GO:2000113	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iPC815.YPO2768,iUTI89_1310.UTI89_C2601	Carboxyl_trans
k59_1484990_2	159087.Daro_0873	5.55e-80	249.0	COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,2VI0H@28216|Betaproteobacteria,2KV9G@206389|Rhodocyclales	206389|Rhodocyclales	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
k59_1839638_1	1249480.B649_07765	4.82e-28	111.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,42MFC@68525|delta/epsilon subdivisions,2YMN5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iIT341.HP0976	AAA_26,Aminotran_3
k59_1839638_2	1537917.JU82_11265	3.34e-40	141.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,42NFK@68525|delta/epsilon subdivisions,2YNST@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_426958_1	1249480.B649_03920	6.92e-86	261.0	COG0656@1|root,COG0656@2|Bacteria,1PGB3@1224|Proteobacteria,42PPT@68525|delta/epsilon subdivisions,2YN3U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_1306021_1	709032.Sulku_1100	7.27e-67	213.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,42RH7@68525|delta/epsilon subdivisions	1224|Proteobacteria	N	Flagellar motor protein	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
k59_488753_1	1249480.B649_05070	9.2e-140	405.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2YNK5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DEAD box helicase family	dbpA	-	3.6.4.13	ko:K05591	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DEAD,DbpA,Helicase_C
k59_1546028_1	159087.Daro_3951	2.11e-44	152.0	COG0466@1|root,COG0466@2|Bacteria,1MWQ9@1224|Proteobacteria,2VJKY@28216|Betaproteobacteria,2KV7N@206389|Rhodocyclales	206389|Rhodocyclales	O	ATPase family associated with various cellular activities (AAA)	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA
k59_1546028_2	159087.Daro_3947	1.69e-95	279.0	COG0864@1|root,COG0864@2|Bacteria,1RK4R@1224|Proteobacteria,2VR6M@28216|Betaproteobacteria,2KWDQ@206389|Rhodocyclales	206389|Rhodocyclales	K	Transcriptional regulator	-	-	-	ko:K07722	-	-	-	-	ko00000,ko03000	-	-	-	NikR_C,RHH_1
k59_1546028_3	1304883.KI912532_gene1073	2.14e-89	275.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VJGE@28216|Betaproteobacteria,2KV0D@206389|Rhodocyclales	206389|Rhodocyclales	T	His Kinase A (phosphoacceptor) domain	hoxJ	-	2.7.13.3	ko:K19661	ko02020,map02020	M00772	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_4
k59_1308027_1	1165841.SULAR_05878	2.88e-26	105.0	COG2195@1|root,COG2195@2|Bacteria,1MUWK@1224|Proteobacteria,42PS0@68525|delta/epsilon subdivisions,2YMQC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Dipeptidase	pepD	-	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M20
k59_1308027_2	387093.SUN_1807	1.03e-45	156.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,42M26@68525|delta/epsilon subdivisions,2YMEG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	polyphosphate kinase	-	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
k59_960689_1	1537917.JU82_11015	7.29e-20	84.0	2AK46@1|root,31AU1@2|Bacteria,1Q64N@1224|Proteobacteria,432DV@68525|delta/epsilon subdivisions,2YSQ8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_960689_2	1537917.JU82_11020	2.15e-10	61.2	COG3203@1|root,COG3203@2|Bacteria	2|Bacteria	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	oprD	-	-	ko:K08720,ko:K18093	ko01501,ko02020,ko05111,map01501,map02020,map05111	M00745	-	-	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	1.B.1.2.1,1.B.25.1.1	-	iJN746.PP_1206	Alginate_exp,BBP2,OprD,Porin_4
k59_1487979_2	709032.Sulku_1016	4.54e-82	244.0	COG0590@1|root,COG0590@2|Bacteria,1RE8P@1224|Proteobacteria,42RF7@68525|delta/epsilon subdivisions,2YP03@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	FJ	PFAM Cytidine and deoxycytidylate deaminase zinc-binding region	-	-	3.5.4.1	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922	RC00074,RC00514,RC00809	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
k59_669592_1	1150621.SMUL_1136	1.01e-47	178.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,43DDQ@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07709	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA,MASE1,PAS,PAS_4,PAS_9,Response_reg
k59_669593_1	1132855.KB913035_gene2526	2.58e-130	372.0	COG0269@1|root,COG0269@2|Bacteria,1R970@1224|Proteobacteria,2VWTN@28216|Betaproteobacteria,2KKJK@206350|Nitrosomonadales	206350|Nitrosomonadales	G	PFAM Orotidine 5'-phosphate decarboxylase	-	-	4.1.2.43	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	M00345,M00580	R05338	RC00421,RC00422	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
k59_1431999_1	709032.Sulku_1830	1.13e-107	327.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,42NAX@68525|delta/epsilon subdivisions,2YN4X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
k59_1722091_1	1537917.JU82_10080	1.65e-19	82.4	2AWDR@1|root,31N9R@2|Bacteria,1QK0X@1224|Proteobacteria,42U4P@68525|delta/epsilon subdivisions,2YPX5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1138223_1	583345.Mmol_0769	3.02e-93	282.0	28IX1@1|root,2ZC5T@2|Bacteria,1R35E@1224|Proteobacteria,2VQUH@28216|Betaproteobacteria,2KKKU@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Protein of unknown function (DUF2914)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2914
k59_900442_1	717773.Thicy_0649	4.23e-90	278.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,1RNI4@1236|Gammaproteobacteria,4602R@72273|Thiotrichales	72273|Thiotrichales	C	NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
k59_310645_1	1537917.JU82_10775	3.2e-10	68.6	COG0745@1|root,COG0745@2|Bacteria,1QXJT@1224|Proteobacteria,42V47@68525|delta/epsilon subdivisions,2YQ8S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	RESPONSE REGULATOR receiver	-	-	-	ko:K07288	-	-	-	-	ko00000	-	-	-	-
k59_1488027_2	1249480.B649_03065	3.81e-84	265.0	2AJ4C@1|root,319NV@2|Bacteria,1Q3D8@1224|Proteobacteria,431S6@68525|delta/epsilon subdivisions,2YS5U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1022610_1	1510531.JQJJ01000011_gene2921	4.77e-43	158.0	COG0553@1|root,COG0553@2|Bacteria,1R7CK@1224|Proteobacteria,2U228@28211|Alphaproteobacteria,3JXBV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	DNA methylase N-4	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,N6_N4_Mtase
k59_1022610_2	1120971.AUCA01000053_gene371	1.64e-105	317.0	COG0863@1|root,COG0863@2|Bacteria,1UZIN@1239|Firmicutes,4HU16@91061|Bacilli	91061|Bacilli	L	DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
k59_1664002_1	983917.RGE_29280	7.44e-56	194.0	COG4772@1|root,COG4772@2|Bacteria,1QVCH@1224|Proteobacteria,2WGQ6@28216|Betaproteobacteria,1KKAI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_1308094_1	1123514.KB905899_gene1251	1.24e-56	186.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,1RSE6@1236|Gammaproteobacteria,460GM@72273|Thiotrichales	72273|Thiotrichales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
k59_430150_1	709032.Sulku_2434	9.09e-40	140.0	COG0679@1|root,COG0679@2|Bacteria,1PHSS@1224|Proteobacteria,42M30@68525|delta/epsilon subdivisions,2YN5E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	auxin efflux carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
k59_1843472_1	543728.Vapar_3056	1.98e-96	290.0	COG1235@1|root,COG1235@2|Bacteria,1MWI5@1224|Proteobacteria,2VJUF@28216|Betaproteobacteria,4AGWJ@80864|Comamonadaceae	28216|Betaproteobacteria	S	May be involved in the transport of PQQ or its precursor to the periplasm	pqqB	-	-	ko:K06136	-	-	-	-	ko00000	-	-	-	Lactamase_B_2
k59_1488052_1	1165841.SULAR_07073	1.63e-89	271.0	COG1493@1|root,COG1493@2|Bacteria,1NN8Y@1224|Proteobacteria	1224|Proteobacteria	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_430162_1	1158165.KB898871_gene2043	1.51e-36	139.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,1RMQN@1236|Gammaproteobacteria,1WWB1@135613|Chromatiales	135613|Chromatiales	T	SMART Nucleotide binding protein, PINc	-	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
k59_1780606_1	709032.Sulku_0689	6.5e-33	121.0	COG0348@1|root,COG0348@2|Bacteria,1MWR5@1224|Proteobacteria,42NMJ@68525|delta/epsilon subdivisions,2YMIN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Ferredoxin-type protein, NapH MauN family	napH	-	-	ko:K02574	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_10,Fer4_5,Fer4_6
k59_1780606_2	709032.Sulku_2613	3.81e-105	306.0	COG3043@1|root,COG3043@2|Bacteria,1NAZB@1224|Proteobacteria,42SN1@68525|delta/epsilon subdivisions,2YPF9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB	napB	-	-	ko:K02568	ko00910,ko01120,map00910,map01120	M00529,M00530	R00798	RC02812	ko00000,ko00001,ko00002	-	-	-	NapB
k59_370092_1	709032.Sulku_0975	1.32e-78	243.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,42NJJ@68525|delta/epsilon subdivisions,2YM8Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
k59_1022685_1	159087.Daro_3990	8.16e-117	378.0	COG0517@1|root,COG2203@1|root,COG3829@1|root,COG5001@1|root,COG0517@2|Bacteria,COG2203@2|Bacteria,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KUCK@206389|Rhodocyclales	206389|Rhodocyclales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CZB,EAL,GAF_2,GGDEF,PAS_4,PAS_9
k59_254786_1	886882.PPSC2_c2354	7.74e-40	147.0	COG0497@1|root,COG0497@2|Bacteria,1TQ08@1239|Firmicutes,4HB6Y@91061|Bacilli,26TBJ@186822|Paenibacillaceae	91061|Bacilli	L	Tubulin like	-	-	-	-	-	-	-	-	-	-	-	-	Tubulin_2
k59_254786_2	358681.BBR47_57160	1.72e-30	120.0	COG2304@1|root,COG2304@2|Bacteria,1UYIW@1239|Firmicutes,4HRS3@91061|Bacilli,26SAJ@186822|Paenibacillaceae	91061|Bacilli	S	Von Willebrand factor	vWFA1	-	-	-	-	-	-	-	-	-	-	-	VWA
k59_1432139_1	1121937.AUHJ01000001_gene494	2.24e-49	171.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RP0W@1236|Gammaproteobacteria,465KZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor	bioA	GO:0003674,GO:0003824,GO:0004015,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iUTI89_1310.UTI89_C0772,iZ_1308.Z0993	Aminotran_3
k59_608255_1	754476.Q7A_527	5.58e-47	171.0	COG0715@1|root,COG0834@1|root,COG5001@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,45ZS0@72273|Thiotrichales	72273|Thiotrichales	T	Diguanylate cyclase phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,NMT1,PAS_9,SBP_bac_3
k59_719550_1	1537917.JU82_11285	1.59e-140	409.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2YM8S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
k59_1308153_1	265072.Mfla_2160	9.8e-34	123.0	COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,2VR4C@28216|Betaproteobacteria,2KMNW@206350|Nitrosomonadales	206350|Nitrosomonadales	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
k59_1308153_2	1502770.JQMG01000001_gene271	8.01e-19	84.0	COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,2VJP9@28216|Betaproteobacteria,2KM9I@206350|Nitrosomonadales	206350|Nitrosomonadales	H	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway	bioC	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
k59_1604444_1	944547.ABLL_0037	1.17e-28	120.0	COG3290@1|root,COG4191@1|root,COG3290@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.1.1.80,2.7.13.3,3.1.1.61	ko:K07717,ko:K13040,ko:K13924	ko02020,ko02030,map02020,map02030	M00506,M00514,M00518	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,NMT1,PAS,PAS_9,SBP_bac_3
k59_1780647_1	709032.Sulku_0231	5.79e-92	269.0	COG2346@1|root,COG2346@2|Bacteria,1Q5UZ@1224|Proteobacteria,42U39@68525|delta/epsilon subdivisions,2YPTS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COG2346 Truncated hemoglobins	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
k59_1722213_1	626418.bglu_1g12740	2.38e-28	109.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,2VH8A@28216|Betaproteobacteria,1K21S@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
k59_1722213_2	1279017.AQYJ01000026_gene341	3.97e-42	143.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,1RN75@1236|Gammaproteobacteria,466FX@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
k59_782121_2	1219031.BBJR01000024_gene411	3.08e-41	152.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,4AH6F@80864|Comamonadaceae	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_4,PAS_9,Response_reg
k59_310719_1	1537917.JU82_07125	2.1e-27	104.0	COG1413@1|root,COG1413@2|Bacteria,1NMDT@1224|Proteobacteria,42WYR@68525|delta/epsilon subdivisions,2YQSX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_310719_2	1537917.JU82_07120	5.11e-105	315.0	COG2897@1|root,COG2897@2|Bacteria,1PI99@1224|Proteobacteria,42PX2@68525|delta/epsilon subdivisions,2YNFU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
k59_430219_1	1163617.SCD_n00130	1.95e-110	329.0	COG3039@1|root,COG3039@2|Bacteria,1MUVI@1224|Proteobacteria,2VK9J@28216|Betaproteobacteria	28216|Betaproteobacteria	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
k59_960838_1	1454004.AW11_00020	2.46e-40	134.0	COG0636@1|root,32S3K@2|Bacteria,1N1NA@1224|Proteobacteria,2VTY0@28216|Betaproteobacteria,1KQ3M@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
k59_960838_2	159087.Daro_4108	5.39e-96	285.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,2VHR5@28216|Betaproteobacteria,2KVA0@206389|Rhodocyclales	206389|Rhodocyclales	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
k59_370152_1	1537917.JU82_08625	2.65e-213	588.0	COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,42MNQ@68525|delta/epsilon subdivisions,2YMQ5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	glycyl-tRNA synthetase alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
k59_1369997_1	1249480.B649_02875	4.39e-72	217.0	COG0594@1|root,COG0594@2|Bacteria,1NGQJ@1224|Proteobacteria,42U9K@68525|delta/epsilon subdivisions,2YQ3Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
k59_608332_2	1165841.SULAR_01275	6.78e-27	102.0	COG0789@1|root,COG0789@2|Bacteria,1Q3QJ@1224|Proteobacteria,42XN5@68525|delta/epsilon subdivisions,2YR08@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	MerR HTH family regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
k59_608332_3	1537917.JU82_03470	2.49e-40	135.0	28QM5@1|root,319KE@2|Bacteria,1Q3DZ@1224|Proteobacteria,42X5X@68525|delta/epsilon subdivisions,2YQT9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
k59_492158_1	522306.CAP2UW1_0749	2.27e-79	249.0	COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,2VHTW@28216|Betaproteobacteria,1KQCQ@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	EGP	Drug resistance transporter Bcr CflA subfamily	-	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1
k59_492158_2	997829.HMPREF1121_00326	6.99e-10	59.3	COG0606@1|root,COG0606@2|Bacteria,4NE0G@976|Bacteroidetes,2FMHE@200643|Bacteroidia,22W0Y@171551|Porphyromonadaceae	976|Bacteroidetes	O	magnesium chelatase	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
k59_669865_2	323848.Nmul_A0451	0.000238	43.5	COG0526@1|root,COG0526@2|Bacteria,1N4HY@1224|Proteobacteria,2VSKM@28216|Betaproteobacteria,3738Z@32003|Nitrosomonadales	28216|Betaproteobacteria	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
k59_140277_1	709032.Sulku_1663	4.76e-100	306.0	COG2199@1|root,COG2200@1|root,COG2200@2|Bacteria,COG3706@2|Bacteria,1Q49C@1224|Proteobacteria,42MW2@68525|delta/epsilon subdivisions,2YNR7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PFAM EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,Response_reg
k59_1077668_1	1537917.JU82_09485	5.43e-125	366.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,42MGM@68525|delta/epsilon subdivisions,2YMUV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
k59_1664144_1	1249480.B649_10555	5.69e-118	352.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MSP@68525|delta/epsilon subdivisions,2YNDA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
k59_1370029_1	317025.Tcr_1548	4.22e-120	369.0	COG0466@1|root,COG0466@2|Bacteria,1NTR5@1224|Proteobacteria,1RPID@1236|Gammaproteobacteria,461XY@72273|Thiotrichales	72273|Thiotrichales	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_1604530_1	94122.Shewana3_0022	1.33e-89	279.0	COG2199@1|root,COG2199@2|Bacteria,1NYG9@1224|Proteobacteria,1RV5M@1236|Gammaproteobacteria,2QD9V@267890|Shewanellaceae	1236|Gammaproteobacteria	T	Protoglobin	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Protoglobin
k59_552796_1	159087.Daro_2406	5.54e-83	261.0	COG1269@1|root,COG1269@2|Bacteria,1MXZG@1224|Proteobacteria,2VMAH@28216|Betaproteobacteria,2KUGS@206389|Rhodocyclales	206389|Rhodocyclales	C	Protein of unknown function (DUF3485)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3485,Exosortase_EpsH
k59_843544_1	1249480.B649_01215	2.1e-72	239.0	COG0457@1|root,COG0457@2|Bacteria,1QV1A@1224|Proteobacteria,42MIW@68525|delta/epsilon subdivisions,2YMDB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Paralysed flagella protein	pflA	-	-	-	-	-	-	-	-	-	-	-	TPR_21,TPR_6,TPR_8,YfiO
k59_492179_1	1249480.B649_03700	3.96e-175	512.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2YMM8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	cation transport ATPase	copA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
k59_492179_2	1249480.B649_03695	2.12e-26	98.6	COG3462@1|root,COG3462@2|Bacteria,1Q6M9@1224|Proteobacteria,432UC@68525|delta/epsilon subdivisions,2YSNX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	membrane protein (DUF2078)	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	-
k59_900607_2	709032.Sulku_1041	2e-120	359.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42P4R@68525|delta/epsilon subdivisions,2YM92@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	DUF3365,HAMP,MCPsignal
k59_1843695_1	1249480.B649_03945	5.12e-77	250.0	COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,42MP9@68525|delta/epsilon subdivisions	1224|Proteobacteria	V	ABC transporter, transmembrane region	rtxB	-	-	ko:K12541	ko02010,map02010	M00330	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.109.3,3.A.1.109.4	-	-	ABC_membrane,ABC_tran,Peptidase_C39
k59_194698_1	1304883.KI912532_gene602	2.57e-30	114.0	COG1560@1|root,COG1560@2|Bacteria,1Q41N@1224|Proteobacteria,2VKN0@28216|Betaproteobacteria,2KUY8@206389|Rhodocyclales	206389|Rhodocyclales	M	acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
k59_194698_2	580332.Slit_0177	3.03e-17	80.1	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,2VH7U@28216|Betaproteobacteria,44VJJ@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
k59_140316_2	1249480.B649_06625	1.61e-189	533.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,42NSY@68525|delta/epsilon subdivisions,2YNJN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	-	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
k59_1843715_1	1537917.JU82_06155	2.38e-42	149.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2YMN1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DEAD box helicase family	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k59_1719843_1	1240350.AMZE01000106_gene1757	3.62e-73	235.0	COG1492@1|root,COG1492@2|Bacteria,1MUFY@1224|Proteobacteria,1RP8G@1236|Gammaproteobacteria,1YVRM@136845|Pseudomonas putida group	1236|Gammaproteobacteria	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,CbiA,GATase_3
k59_137684_1	1537917.JU82_01000	1.49e-113	340.0	COG1956@1|root,COG3604@1|root,COG1956@2|Bacteria,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,42Y69@68525|delta/epsilon subdivisions,2YNEN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	Transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF_2,HTH_8,Sigma54_activat
k59_1191347_1	1249480.B649_05085	5.86e-95	298.0	COG1344@1|root,COG1344@2|Bacteria,1N1QF@1224|Proteobacteria,42PDD@68525|delta/epsilon subdivisions,2YMYD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	flgL	-	-	ko:K02397	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
k59_490009_1	709032.Sulku_1298	5.71e-92	270.0	COG1433@1|root,COG1433@2|Bacteria,1RD9P@1224|Proteobacteria,42W01@68525|delta/epsilon subdivisions,2YQEH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Dinitrogenase iron-molybdenum cofactor biosynthesis protein	-	-	-	ko:K02596	-	-	-	-	ko00000	-	-	-	Nitro_FeMo-Co
k59_1367749_1	1304885.AUEY01000069_gene1436	1.69e-63	204.0	COG0657@1|root,COG0657@2|Bacteria,1R4AU@1224|Proteobacteria,42XIQ@68525|delta/epsilon subdivisions,2WSR5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
k59_1075372_2	709032.Sulku_1652	3.32e-57	184.0	COG0656@1|root,COG0656@2|Bacteria,1PGB3@1224|Proteobacteria,42PPT@68525|delta/epsilon subdivisions,2YN3U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_1547327_1	387093.SUN_1903	8.08e-26	104.0	COG2198@1|root,COG2198@2|Bacteria	2|Bacteria	T	Histidine kinase	rcsD	GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009927,GO:0009987,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0031224,GO:0031226,GO:0035556,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0071704,GO:0071944,GO:0140096,GO:1901564	2.7.13.3	ko:K07676,ko:K10715,ko:K20976	ko02020,ko02024,ko02025,ko02026,map02020,map02024,map02025,map02026	M00474,M00517,M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Hpt,RcsD_ABL,Response_reg
k59_1547327_2	1165841.SULAR_06318	3.42e-36	138.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2YMJS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,NIT,Response_reg
k59_667122_1	1225785.CM001983_gene2563	8.49e-28	108.0	COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,1RMD0@1236|Gammaproteobacteria,2JCPZ@204037|Dickeya	1236|Gammaproteobacteria	T	Two component transcriptional regulator, winged helix family	baeR	GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001023,GO:2001141	-	ko:K07664,ko:K18144	ko01501,ko02020,map01501,map02020	M00450,M00645,M00646,M00648,M00649,M00655	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_1778668_1	1537917.JU82_11280	1.15e-122	367.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,42MPK@68525|delta/epsilon subdivisions,2YMFX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,SurA_N_3
k59_841226_1	1249480.B649_04705	8.22e-115	365.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2YMRQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_1019870_1	1304883.KI912532_gene5	8.58e-73	223.0	COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,2VQ7P@28216|Betaproteobacteria,2KW5B@206389|Rhodocyclales	206389|Rhodocyclales	S	Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
k59_1135966_1	1304883.KI912532_gene574	1.23e-96	292.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,2VHXR@28216|Betaproteobacteria,2KURZ@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
k59_137719_1	159087.Daro_4195	1.73e-147	419.0	COG3713@1|root,COG3713@2|Bacteria,1R5JE@1224|Proteobacteria,2VKVW@28216|Betaproteobacteria,2KVV9@206389|Rhodocyclales	206389|Rhodocyclales	M	MltA-interacting protein MipA	-	-	-	-	-	-	-	-	-	-	-	-	MipA
k59_137719_2	1123393.KB891316_gene2067	1.91e-71	225.0	COG0251@1|root,COG0251@2|Bacteria,1NQGP@1224|Proteobacteria,2VMPK@28216|Betaproteobacteria,1KSQI@119069|Hydrogenophilales	119069|Hydrogenophilales	J	pteridine-dependent deoxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_430347_1	1123325.JHUV01000008_gene653	9.97e-30	121.0	COG1538@1|root,COG1538@2|Bacteria,2G552@200783|Aquificae	200783|Aquificae	MU	Outer membrane efflux protein	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
k59_843617_1	375286.mma_0286	6.02e-70	239.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2VKKR@28216|Betaproteobacteria,476GP@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	AcrB/AcrD/AcrF family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
k59_254972_1	709032.Sulku_0994	1.68e-45	149.0	COG1558@1|root,COG1558@2|Bacteria,1R09B@1224|Proteobacteria	1224|Proteobacteria	N	Flagellar basal body rod FlgEFG protein C-terminal	-	-	-	ko:K02388	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k59_254972_2	1249480.B649_05590	3.43e-81	251.0	COG2171@1|root,COG2171@2|Bacteria,1MYKK@1224|Proteobacteria,42MHI@68525|delta/epsilon subdivisions,2YMU8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep_2,THDPS_M,THDPS_N
k59_960969_2	709032.Sulku_2356	1.59e-79	243.0	COG0124@1|root,COG0124@2|Bacteria,1QUJQ@1224|Proteobacteria,42NX2@68525|delta/epsilon subdivisions,2YN2F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	PFAM tRNA synthetase class II (G H P and S)	hisZ	-	-	-	-	-	-	-	-	-	-	-	tRNA-synt_His
k59_1780836_1	1502770.JQMG01000001_gene1721	5.54e-125	361.0	COG1054@1|root,COG1054@2|Bacteria,1MUFV@1224|Proteobacteria,2VIX6@28216|Betaproteobacteria,2KMBX@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Belongs to the UPF0176 family	-	-	-	ko:K07146	-	-	-	-	ko00000	-	-	-	Rhodanese
k59_1370134_1	709032.Sulku_2194	3.62e-128	375.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,42M8P@68525|delta/epsilon subdivisions,2YN6C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	peptidase U32 family	prtC	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
k59_1193542_1	1249480.B649_04050	1.48e-103	320.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YMHP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_1432440_2	709032.Sulku_2471	1.25e-76	237.0	COG0348@1|root,COG0348@2|Bacteria,1Q4B9@1224|Proteobacteria,42P8A@68525|delta/epsilon subdivisions,2YNTH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_10,Fer4_5
k59_552936_1	296591.Bpro_3279	1.67e-73	245.0	COG0243@1|root,COG1251@1|root,COG0243@2|Bacteria,COG1251@2|Bacteria,1NS3T@1224|Proteobacteria,2VIB1@28216|Betaproteobacteria,4AB7E@80864|Comamonadaceae	28216|Betaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	nasA	-	-	ko:K00372	ko00910,ko01120,map00910,map01120	M00531	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_1077785_1	903818.KI912268_gene2856	9.9e-65	219.0	COG0028@1|root,COG0028@2|Bacteria,3Y3TV@57723|Acidobacteria	57723|Acidobacteria	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_310859_1	1249480.B649_00305	2.45e-85	277.0	COG2911@1|root,COG2911@2|Bacteria,1PBYT@1224|Proteobacteria,42T65@68525|delta/epsilon subdivisions,2YPPD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
k59_961001_1	159087.Daro_4149	1.66e-96	294.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,2VIEV@28216|Betaproteobacteria,2KV3Q@206389|Rhodocyclales	206389|Rhodocyclales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN1	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
k59_961001_2	1304883.KI912532_gene884	1.41e-48	155.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,2VU5H@28216|Betaproteobacteria,2KWTT@206389|Rhodocyclales	206389|Rhodocyclales	J	sigma 54 modulation protein	-	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
k59_19506_1	522306.CAP2UW1_1087	1.03e-09	55.8	COG2138@1|root,COG2138@2|Bacteria,1N00J@1224|Proteobacteria,2VTXE@28216|Betaproteobacteria,1KQ4M@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	CbiX	cbiX	-	4.99.1.3	ko:K03795	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiX
k59_19506_2	159087.Daro_0827	1.32e-77	242.0	COG0477@1|root,COG2814@2|Bacteria,1MXPM@1224|Proteobacteria,2VHXT@28216|Betaproteobacteria,2KVE0@206389|Rhodocyclales	206389|Rhodocyclales	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
k59_900694_2	1249480.B649_03915	8.08e-116	333.0	COG1051@1|root,COG1051@2|Bacteria,1PNK8@1224|Proteobacteria,42YE5@68525|delta/epsilon subdivisions,2YR8Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	NUDIX domain	-	-	3.6.1.62,3.6.1.64	ko:K16855	ko00230,ko03018,map00230,map03018	-	R00961,R10235,R10815	RC00002	ko00000,ko00001,ko01000,ko03019	-	-	-	NUDIX
k59_900694_3	709032.Sulku_1583	2.01e-116	340.0	COG1305@1|root,COG1305@2|Bacteria,1Q2I2@1224|Proteobacteria,42VRK@68525|delta/epsilon subdivisions,2YQHP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Transglutaminase-like	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
k59_900694_4	29495.EA26_06865	6.9e-17	80.9	COG2770@1|root,COG3437@1|root,COG2770@2|Bacteria,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,1RPH3@1236|Gammaproteobacteria,1XT5R@135623|Vibrionales	135623|Vibrionales	T	COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
k59_1664283_1	1123514.KB905899_gene1140	3.34e-73	238.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,1RPX3@1236|Gammaproteobacteria,461JQ@72273|Thiotrichales	72273|Thiotrichales	F	Belongs to the 5'-nucleotidase family	-	-	-	ko:K17224	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	5_nucleotid_C
k59_670064_1	1537917.JU82_04660	9.92e-63	194.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,42U00@68525|delta/epsilon subdivisions,2YPZU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	transport protein	tolR	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
k59_670064_2	709032.Sulku_0761	2.16e-79	239.0	COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,42PKF@68525|delta/epsilon subdivisions,2YNC3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	MotA TolQ ExbB proton channel family	tolQ	-	-	-	-	-	-	-	-	-	-	-	MotA_ExbB
k59_782365_1	999549.KI421513_gene2044	4.19e-22	103.0	COG0840@1|root,COG2770@1|root,COG0840@2|Bacteria,COG2770@2|Bacteria,1MU9B@1224|Proteobacteria,2TQR7@28211|Alphaproteobacteria,282B0@191028|Leisingera	28211|Alphaproteobacteria	NT	Cache domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,PAS_4,PAS_8,PAS_9,dCache_1
k59_1023076_1	1123393.KB891317_gene2355	5.71e-55	189.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,2VH19@28216|Betaproteobacteria,1KRZR@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1g,tRNA_bind
k59_608523_1	159087.Daro_4112	1.01e-153	444.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,2VHQU@28216|Betaproteobacteria,2KV0S@206389|Rhodocyclales	206389|Rhodocyclales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_140442_1	1249480.B649_00170	2.42e-92	277.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,42M8N@68525|delta/epsilon subdivisions,2YMFN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	hprA	-	1.1.1.29	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	M00346	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
k59_1370197_1	1537917.JU82_03250	1.3e-82	261.0	COG2199@1|root,COG2200@1|root,COG3620@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,COG3620@2|Bacteria,1MVJY@1224|Proteobacteria,42N7E@68525|delta/epsilon subdivisions,2YNE7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PFAM EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF
k59_1432510_1	1249480.B649_06440	2.98e-31	122.0	COG3290@1|root,COG4191@1|root,COG3290@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42R1U@68525|delta/epsilon subdivisions,2YNX6@29547|Epsilonproteobacteria	1224|Proteobacteria	T	PAS domain	-	-	-	ko:K20971	ko02025,map02025	-	-	-	ko00000,ko00001,ko01001,ko02022	-	-	-	HATPase_c,PAS_9
k59_1432510_2	709032.Sulku_1947	1.88e-43	159.0	COG3290@1|root,COG3614@1|root,COG4191@1|root,COG3290@2|Bacteria,COG3614@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42R1U@68525|delta/epsilon subdivisions,2YNX6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,PAS_9
k59_430415_1	159087.Daro_4106	6.42e-93	278.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,2VIG0@28216|Betaproteobacteria,2KU8M@206389|Rhodocyclales	206389|Rhodocyclales	K	Belongs to the ParB family	spoOJ	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
k59_430415_2	159087.Daro_4107	7.8e-38	129.0	COG3312@1|root,COG3312@2|Bacteria	2|Bacteria	C	ATP synthase I chain	atpI	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0044769,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	iSSON_1240.SSON_3880	ATP-synt_I
k59_1308398_1	1537917.JU82_04300	9.92e-53	184.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42MV6@68525|delta/epsilon subdivisions,2YMMC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CHASE3,MCPsignal,NIT
k59_430421_1	159087.Daro_2025	2.17e-13	64.3	COG0526@1|root,COG0526@2|Bacteria,1QVC9@1224|Proteobacteria,2VYGG@28216|Betaproteobacteria,2KXAK@206389|Rhodocyclales	206389|Rhodocyclales	CO	COG0526 Thiol-disulfide isomerase and thioredoxins	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	DUF836
k59_430421_2	159087.Daro_2024	1.18e-101	309.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VI4Q@28216|Betaproteobacteria,2KUVY@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the peptidase S1C family	degQ	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
k59_75623_2	709032.Sulku_0857	2.97e-07	50.1	2FGS9@1|root,348MQ@2|Bacteria,1P3H2@1224|Proteobacteria,42SDS@68525|delta/epsilon subdivisions,2YPE7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF4149
k59_843714_1	314607.KB13_1079	2.69e-83	261.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,2VH45@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Sulfate transporter	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,STAS_2,Sulfate_transp
k59_1843923_1	1049564.TevJSym_aj00710	4.07e-71	235.0	COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,1RZB9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Von willebrand factor, type a	cbbO	-	-	-	-	-	-	-	-	-	-	-	VWA
k59_1843932_1	317025.Tcr_2066	2.69e-13	67.8	COG3201@1|root,COG3201@2|Bacteria,1MXN4@1224|Proteobacteria,1RMZE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	nicotinamide mononucleotide transporter	pnuC	-	-	ko:K03811	-	-	-	-	ko00000,ko02000	4.B.1.1	-	-	NMN_transporter
k59_1843935_1	395494.Galf_2609	2.84e-11	59.7	COG3668@1|root,COG3668@2|Bacteria,1PJWP@1224|Proteobacteria,2W88C@28216|Betaproteobacteria,44WJ0@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
k59_1843935_2	580332.Slit_1213	4.04e-47	152.0	COG2161@1|root,COG2161@2|Bacteria,1NEWX@1224|Proteobacteria,2WCQS@28216|Betaproteobacteria,44WIC@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
k59_1843935_3	222534.KB893720_gene793	1.39e-07	53.9	COG2199@1|root,COG3284@1|root,COG3284@2|Bacteria,COG3706@2|Bacteria,2IA4H@201174|Actinobacteria	201174|Actinobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_430460_1	395495.Lcho_1339	4.14e-60	191.0	COG3005@1|root,COG3005@2|Bacteria,1MWV2@1224|Proteobacteria,2VMSB@28216|Betaproteobacteria,1KPBQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	PFAM NapC NirT cytochrome c	-	-	-	ko:K02569	-	-	-	-	ko00000	-	-	-	Cytochrom_NNT
k59_430460_2	1121035.AUCH01000002_gene1468	1.5e-19	82.0	COG3043@1|root,COG3043@2|Bacteria,1RHGD@1224|Proteobacteria,2VTPE@28216|Betaproteobacteria,2KXA1@206389|Rhodocyclales	206389|Rhodocyclales	C	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB	-	-	-	ko:K02568	ko00910,ko01120,map00910,map01120	M00529,M00530	R00798	RC02812	ko00000,ko00001,ko00002	-	-	-	NapB
k59_1193664_1	1165841.SULAR_09134	3e-75	231.0	COG0470@1|root,COG0470@2|Bacteria,1R9U1@1224|Proteobacteria,42R45@68525|delta/epsilon subdivisions,2YPZZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA polymerase III	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
k59_1664369_1	870187.Thini_1080	1.04e-75	233.0	COG0730@1|root,COG0730@2|Bacteria,1MY0T@1224|Proteobacteria,1RS7K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k59_608613_1	1165841.SULAR_00885	1.13e-56	181.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,42RK3@68525|delta/epsilon subdivisions,2YT63@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
k59_608613_2	1165841.SULAR_00890	6.69e-81	242.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,42RJQ@68525|delta/epsilon subdivisions,2YP4R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
k59_194944_2	159087.Daro_1630	6.97e-35	119.0	29P6R@1|root,30A4V@2|Bacteria,1QT5H@1224|Proteobacteria,2W9YR@28216|Betaproteobacteria,2KZFS@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_310948_2	1002367.HMPREF0673_01682	8.84e-18	79.7	COG1898@1|root,COG1898@2|Bacteria,4NNKW@976|Bacteroidetes,2FMBP@200643|Bacteroidia	976|Bacteroidetes	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
k59_1843998_1	159087.Daro_1281	1.46e-50	160.0	COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,2VSPN@28216|Betaproteobacteria,2KWNF@206389|Rhodocyclales	206389|Rhodocyclales	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	ihfB	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k59_1843998_2	887898.HMPREF0551_0292	6.24e-05	44.7	COG5416@1|root,COG5416@2|Bacteria,1NES0@1224|Proteobacteria,2VWYU@28216|Betaproteobacteria,1K8D5@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Lipopolysaccharide assembly protein A domain	-	-	-	ko:K08992	-	-	-	-	ko00000	-	-	-	LapA_dom
k59_553151_1	1537917.JU82_06935	4.15e-108	332.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,42M2T@68525|delta/epsilon subdivisions,2YMF5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	ATP-dependent CLP protease ATP-binding subunit	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_1488448_1	472759.Nhal_1048	8.13e-35	140.0	COG1067@1|root,COG3638@1|root,COG1067@2|Bacteria,COG3638@2|Bacteria,1MWGB@1224|Proteobacteria,1RMPC@1236|Gammaproteobacteria,1WXPW@135613|Chromatiales	135613|Chromatiales	O	Belongs to the peptidase S16 family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
k59_1432679_1	1163617.SCD_n00969	1.6e-93	294.0	COG0484@1|root,COG0484@2|Bacteria,1MXM9@1224|Proteobacteria,2VPQ6@28216|Betaproteobacteria	28216|Betaproteobacteria	C	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII
k59_900820_2	1172190.M947_09105	3.44e-39	135.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,42U00@68525|delta/epsilon subdivisions,2YPZU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	transport protein	tolR	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
k59_1432689_1	494416.AYXN01000041_gene513	2.76e-97	301.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,1RMM1@1236|Gammaproteobacteria,3NKEB@468|Moraxellaceae	1236|Gammaproteobacteria	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
k59_1432704_1	305700.B447_04023	3.61e-91	275.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,2VHUJ@28216|Betaproteobacteria,2KWM7@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
k59_430544_1	563040.Saut_0847	4.4e-120	376.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YMMN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_719857_1	452637.Oter_1467	2.62e-70	230.0	COG2067@1|root,COG2067@2|Bacteria,46U6Z@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Outer membrane protein transport protein (OMPP1/FadL/TodX)	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k59_782569_1	159087.Daro_3502	1.86e-125	369.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,2VH2H@28216|Betaproteobacteria,2KVHS@206389|Rhodocyclales	206389|Rhodocyclales	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_1193763_1	1249480.B649_08765	5.49e-97	301.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42N29@68525|delta/epsilon subdivisions,2YMFM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA helicase	rep	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_1138761_1	118005.AWNK01000007_gene538	1.13e-22	100.0	COG1450@1|root,COG1450@2|Bacteria	2|Bacteria	NU	protein transport across the cell outer membrane	outD	-	-	ko:K02453,ko:K12282	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N_2
k59_1604876_1	1249480.B649_09050	2.44e-80	260.0	COG0457@1|root,COG0457@2|Bacteria,1QV15@1224|Proteobacteria,42NKI@68525|delta/epsilon subdivisions,2YMKG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	COG0457 FOG TPR repeat	pflB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_6,TPR_8
k59_553237_1	29581.BW37_03483	1.78e-13	70.1	COG1334@1|root,COG1334@2|Bacteria,1NH9T@1224|Proteobacteria,2VXXM@28216|Betaproteobacteria,4755Q@75682|Oxalobacteraceae	28216|Betaproteobacteria	N	FlaG protein	flaG	-	-	ko:K06603	-	-	-	-	ko00000,ko02035	-	-	-	FlaG
k59_553237_2	1123487.KB892836_gene3097	2.31e-15	77.8	COG1345@1|root,COG1345@2|Bacteria,1MUVP@1224|Proteobacteria,2VHMK@28216|Betaproteobacteria,2KUJB@206389|Rhodocyclales	206389|Rhodocyclales	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	-	-	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_IN,FliD_C,FliD_N
k59_1224764_2	709032.Sulku_0137	3.23e-49	169.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,42ND6@68525|delta/epsilon subdivisions,2YN5S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
k59_1173726_1	313628.LNTAR_17298	1.77e-46	158.0	COG0566@1|root,COG0566@2|Bacteria	2|Bacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	spoU	-	2.1.1.185	ko:K03218,ko:K03437	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	SpoU_methylase
k59_1519100_1	159087.Daro_4165	0.000289	42.4	COG0842@1|root,COG0842@2|Bacteria,1N55T@1224|Proteobacteria,2VJ7R@28216|Betaproteobacteria,2KVIE@206389|Rhodocyclales	206389|Rhodocyclales	V	ABC-2 type transporter	nodJ	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
k59_1813508_2	1249480.B649_11040	1.5e-99	295.0	COG1013@1|root,COG1013@2|Bacteria,1MUY9@1224|Proteobacteria,42MQY@68525|delta/epsilon subdivisions,2YMWJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	pyruvate ferredoxin oxidoreductase	porB	-	1.2.7.1	ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
k59_1113196_2	709032.Sulku_0367	1.03e-123	357.0	COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,42MQQ@68525|delta/epsilon subdivisions,2YNAG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	dna polymerase iii	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_50166_1	159087.Daro_0511	1.08e-104	318.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,2VJG4@28216|Betaproteobacteria,2KV2I@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
k59_527351_2	1538295.JY96_20355	1.02e-154	444.0	COG0446@1|root,COG0446@2|Bacteria,1QSG7@1224|Proteobacteria,2W9DB@28216|Betaproteobacteria,1KKDR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_465130_2	1304888.ATWF01000001_gene2325	4.37e-34	132.0	COG2199@1|root,COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,COG4191@2|Bacteria,2GGBB@200930|Deferribacteres	200930|Deferribacteres	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_9
k59_1345370_1	709032.Sulku_1997	1.82e-80	262.0	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42Z31@68525|delta/epsilon subdivisions,2YRAR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Hpt sensor hybrid histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
k59_1813573_1	1537917.JU82_02875	1.22e-131	380.0	COG0348@1|root,COG0348@2|Bacteria,1Q4B9@1224|Proteobacteria,42P8A@68525|delta/epsilon subdivisions,2YNTH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_10,Fer4_5
k59_1228568_1	1304883.KI912532_gene1941	2.02e-109	343.0	COG1305@1|root,COG4196@1|root,COG1305@2|Bacteria,COG4196@2|Bacteria,1MVAG@1224|Proteobacteria,2VKKZ@28216|Betaproteobacteria,2KV93@206389|Rhodocyclales	206389|Rhodocyclales	E	Putative amidoligase enzyme (DUF2126)	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,DUF2126,Transglut_core
k59_1345397_1	1196095.GAPWK_1662	1.12e-59	198.0	COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,1RN46@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016782,GO:0018193,GO:0018197,GO:0018198,GO:0018339,GO:0019538,GO:0035596,GO:0035599,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901564	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
k59_1405769_1	159087.Daro_4053	2.27e-17	86.3	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,2VH9R@28216|Betaproteobacteria,2KUUQ@206389|Rhodocyclales	206389|Rhodocyclales	U	Involved in the tonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
k59_750084_1	90814.KL370892_gene2336	7.05e-83	275.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,45ZPF@72273|Thiotrichales	72273|Thiotrichales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_343366_1	159087.Daro_0226	6.44e-95	291.0	COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,2VIJ8@28216|Betaproteobacteria,2KVRS@206389|Rhodocyclales	206389|Rhodocyclales	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
k59_1642225_1	497321.C664_18714	1.93e-13	71.2	COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,2VJTA@28216|Betaproteobacteria,2KWA3@206389|Rhodocyclales	206389|Rhodocyclales	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	-	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_IN,Flagellin_N
k59_289925_2	265072.Mfla_1747	5.11e-12	64.3	2ENVQ@1|root,33GGS@2|Bacteria,1NGVT@1224|Proteobacteria,2VY6X@28216|Betaproteobacteria,2KND3@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Protein of unknown function (DUF2934)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2934
k59_1698518_1	159087.Daro_2173	3.11e-127	378.0	COG3519@1|root,COG3519@2|Bacteria,1MUY4@1224|Proteobacteria,2VHXS@28216|Betaproteobacteria,2KWBQ@206389|Rhodocyclales	206389|Rhodocyclales	S	Type VI secretion system, TssF	-	-	-	ko:K11896	-	M00334	-	-	ko00000,ko00002,ko02044	3.A.23.1	-	-	T6SS_TssF
k59_343402_1	709032.Sulku_0128	5.35e-127	363.0	COG3665@1|root,COG3665@2|Bacteria,1N9DM@1224|Proteobacteria,42QUI@68525|delta/epsilon subdivisions,2YP0W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function (DUF1989)	-	-	-	ko:K09967	-	-	-	-	ko00000	-	-	-	DUF1989
k59_343402_2	709032.Sulku_0127	2.91e-29	110.0	COG3665@1|root,COG3665@2|Bacteria,1N2KR@1224|Proteobacteria,42S17@68525|delta/epsilon subdivisions,2YPCG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function (DUF1989)	-	-	-	ko:K09967	-	-	-	-	ko00000	-	-	-	DUF1989
k59_1759192_1	159087.Daro_2189	8.57e-30	116.0	COG0304@1|root,COG0304@2|Bacteria,1N4Y1@1224|Proteobacteria,2VU11@28216|Betaproteobacteria,2KXPZ@206389|Rhodocyclales	206389|Rhodocyclales	IQ	beta-ketoacyl-acyl-carrier-protein synthase II activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1759192_2	159087.Daro_2190	1.7e-48	155.0	COG4104@1|root,COG4104@2|Bacteria,1N1KY@1224|Proteobacteria,2VV5T@28216|Betaproteobacteria,2KYY5@206389|Rhodocyclales	206389|Rhodocyclales	S	PAAR motif	-	-	-	-	-	-	-	-	-	-	-	-	PAAR_motif
k59_1759192_3	159087.Daro_2191	2e-21	90.5	COG1876@1|root,COG1876@2|Bacteria,1MXWT@1224|Proteobacteria,2VPJ2@28216|Betaproteobacteria,2KX3A@206389|Rhodocyclales	206389|Rhodocyclales	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	ko:K17733	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M15_4
k59_50282_2	1249480.B649_04825	7.75e-42	152.0	COG0755@1|root,COG1333@1|root,COG0755@2|Bacteria,COG1333@2|Bacteria,1RG0A@1224|Proteobacteria,42N37@68525|delta/epsilon subdivisions,2YMXW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Cytochrome c biogenesis protein	ccsBA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
k59_343443_1	317025.Tcr_1145	2.62e-45	162.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,1RNGV@1236|Gammaproteobacteria,45ZPV@72273|Thiotrichales	72273|Thiotrichales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
k59_1345524_1	1283336.Q6KGL2_BPFO1	1.05e-21	91.3	4QFUH@10239|Viruses,4QZ2M@35237|dsDNA viruses  no RNA stage,4QSQV@28883|Caudovirales	28883|Caudovirales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1759231_1	1122603.ATVI01000006_gene261	1.02e-11	60.5	COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,1SCA2@1236|Gammaproteobacteria,1X7E1@135614|Xanthomonadales	135614|Xanthomonadales	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	grxC	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
k59_1759231_2	395494.Galf_0222	6.8e-77	231.0	COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,2VQ1Q@28216|Betaproteobacteria,44VTN@713636|Nitrosomonadales	28216|Betaproteobacteria	U	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA	secB	-	-	ko:K03071	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03110	3.A.5	-	-	SecB
k59_874823_1	95619.PM1_0216500	1.76e-96	313.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	GO:0000166,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016884,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	iECH74115_1262.ECH74115_3792,iECO111_1330.ECO111_3283,iECSP_1301.ECSP_3501,iECs_1301.ECs3423,iG2583_1286.G2583_3088,iJN746.PP_1037,ic_1306.c3080	AIRS_C,GATase_5
k59_1642290_1	425104.Ssed_2865	1.45e-46	171.0	COG0642@1|root,COG0834@1|root,COG5002@1|root,COG0642@2|Bacteria,COG0834@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,2QACP@267890|Shewanellaceae	1236|Gammaproteobacteria	T	histidine kinase A domain protein	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	CHASE,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,SBP_bac_3,dCache_1
k59_107360_1	387093.SUN_0616	1.98e-69	224.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2YM8S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
k59_289973_1	1123517.JOMR01000001_gene886	6.86e-115	348.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,460A8@72273|Thiotrichales	72273|Thiotrichales	NU	Secretion system protein	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
k59_527575_1	159087.Daro_1195	2.52e-108	317.0	COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,2VJ8E@28216|Betaproteobacteria,2KVBA@206389|Rhodocyclales	206389|Rhodocyclales	O	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate	ate	-	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	ATE_C,ATE_N
k59_1698591_1	709032.Sulku_1845	7.33e-117	363.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,42MGK@68525|delta/epsilon subdivisions,2YMHU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_527576_1	1537917.JU82_10760	8.79e-114	330.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,42PQP@68525|delta/epsilon subdivisions,2YNQ7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	abc transporter atp-binding protein	ybbA	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_1228759_1	709032.Sulku_2610	3.24e-145	434.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,42M9Q@68525|delta/epsilon subdivisions,2YMEW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC	napA	-	-	ko:K02567	ko00910,ko01120,map00910,map01120	M00529,M00530	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
k59_1698612_2	1249480.B649_11700	8.8e-20	84.3	COG0302@1|root,COG0302@2|Bacteria,1MY3N@1224|Proteobacteria,42N1U@68525|delta/epsilon subdivisions,2YMVV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	GTP cyclohydrolase	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0928	GTP_cyclohydroI
k59_465421_1	159087.Daro_0738	1.72e-71	234.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VI5B@28216|Betaproteobacteria,2KV2C@206389|Rhodocyclales	206389|Rhodocyclales	NT	COG0643 Chemotaxis protein histidine kinase and related kinases	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
k59_465421_2	159087.Daro_0737	1.44e-81	249.0	COG3143@1|root,COG3143@2|Bacteria,1NIV6@1224|Proteobacteria,2VN5G@28216|Betaproteobacteria,2KUP2@206389|Rhodocyclales	206389|Rhodocyclales	NT	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)	cheZ	-	-	ko:K03414	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheZ
k59_938718_2	159087.Daro_1407	2.54e-61	197.0	2E2KC@1|root,32XPP@2|Bacteria,1R4ZI@1224|Proteobacteria,2VM8Z@28216|Betaproteobacteria,2KWU6@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1228812_1	398767.Glov_1958	6.53e-23	100.0	2EBZF@1|root,335YR@2|Bacteria,1N4ZF@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_34
k59_1522617_1	1165841.SULAR_05163	3.66e-24	94.4	COG1393@1|root,COG1393@2|Bacteria,1MZ4Z@1224|Proteobacteria,42TRM@68525|delta/epsilon subdivisions,2YQ2J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1393 Arsenate reductase and related	-	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
k59_1522617_2	1537917.JU82_08905	1.12e-144	429.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2YMW5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,TarH,dCache_2,sCache_2
k59_1759344_1	159087.Daro_1109	8.35e-47	162.0	COG0348@1|root,COG0348@2|Bacteria,1N605@1224|Proteobacteria,2VK7D@28216|Betaproteobacteria,2KUX4@206389|Rhodocyclales	206389|Rhodocyclales	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
k59_404689_1	159087.Daro_3214	5.98e-132	394.0	COG1765@1|root,COG1944@1|root,COG1765@2|Bacteria,COG1944@2|Bacteria,1MV7K@1224|Proteobacteria,2VHZY@28216|Betaproteobacteria,2KV2Z@206389|Rhodocyclales	206389|Rhodocyclales	O	redox protein, regulator of disulfide bond formation	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	OsmC,YcaO
k59_465478_1	156889.Mmc1_2943	4.25e-24	102.0	COG2199@1|root,COG4753@1|root,COG3706@2|Bacteria,COG4753@2|Bacteria,1R7HC@1224|Proteobacteria,2TQQM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	response regulator containing a CheY-like receiver domain and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Reg_prop,Response_reg
k59_465478_2	709032.Sulku_1369	6.48e-21	88.2	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,42QXV@68525|delta/epsilon subdivisions,2YNXY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
k59_1406056_1	1537917.JU82_02515	1.1e-157	447.0	COG2957@1|root,COG2957@2|Bacteria,1MX65@1224|Proteobacteria,42NAS@68525|delta/epsilon subdivisions,2YN3V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the agmatine deiminase family	aguA	-	-	-	-	-	-	-	-	-	-	-	PAD_porph
k59_404727_1	709032.Sulku_0018	1.36e-93	305.0	COG2911@1|root,COG2911@2|Bacteria,1PBYT@1224|Proteobacteria,42T65@68525|delta/epsilon subdivisions,2YPPD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
k59_1345681_1	1537917.JU82_09285	3.3e-73	220.0	COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,42RVK@68525|delta/epsilon subdivisions,2YT6X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	DnaK suppressor protein	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
k59_1345681_2	709032.Sulku_1133	1.22e-76	237.0	29CAW@1|root,2ZZ9C@2|Bacteria,1Q5FH@1224|Proteobacteria,42Q2S@68525|delta/epsilon subdivisions,2YP18@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_343671_1	159087.Daro_2114	6.07e-60	197.0	COG2170@1|root,COG2170@2|Bacteria,1MX4N@1224|Proteobacteria,2VK27@28216|Betaproteobacteria,2KVTN@206389|Rhodocyclales	206389|Rhodocyclales	H	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	ybdK	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
k59_343671_2	279714.FuraDRAFT_2221	7.68e-19	85.9	COG0204@1|root,COG0204@2|Bacteria,1MWDY@1224|Proteobacteria,2VJ4I@28216|Betaproteobacteria,2KPYV@206351|Neisseriales	206351|Neisseriales	I	Transporter, major facilitator family protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,MFS_1
k59_1522690_1	1165841.SULAR_00135	1.17e-70	232.0	COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,42MY0@68525|delta/epsilon subdivisions,2YMT1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
k59_1642478_1	709032.Sulku_2177	1.48e-38	133.0	COG0494@1|root,COG0494@2|Bacteria,1QSQG@1224|Proteobacteria,42RR5@68525|delta/epsilon subdivisions,2YP9Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Nudix domain	-	-	3.6.1.45	ko:K08077	-	-	-	-	ko00000,ko01000	-	-	-	NUDIX
k59_1642478_2	1249480.B649_10290	4.13e-235	652.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42MNF@68525|delta/epsilon subdivisions,2YMW2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_1642478_3	1537917.JU82_02535	1.01e-90	272.0	COG2863@1|root,COG2863@2|Bacteria,1Q4WC@1224|Proteobacteria,42NFN@68525|delta/epsilon subdivisions,2YMWE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Plasminogen-binding protein pgbA N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PGBA_N
k59_1406166_2	1408813.AYMG01000027_gene5307	1.3e-26	105.0	COG4464@1|root,COG4464@2|Bacteria,4NMUT@976|Bacteroidetes,1IS2C@117747|Sphingobacteriia	976|Bacteroidetes	GM	COG4464 Capsular polysaccharide biosynthesis protein	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
k59_1642514_1	365044.Pnap_0796	3.4e-54	186.0	COG0318@1|root,COG0318@2|Bacteria,1MUQZ@1224|Proteobacteria,2VIB6@28216|Betaproteobacteria,4ACZX@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	fcs	-	6.2.1.34	ko:K12508	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding
k59_1642514_2	296591.Bpro_3111	3.98e-06	47.8	COG1024@1|root,COG1024@2|Bacteria,1MWYZ@1224|Proteobacteria,2VJYU@28216|Betaproteobacteria,4AB6X@80864|Comamonadaceae	28216|Betaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.155	ko:K20036	ko00920,map00920	-	R10936	RC00004,RC03306,RC03307	ko00000,ko00001,ko01000	-	-	-	ECH_1
k59_1522724_1	159087.Daro_0128	4.18e-110	327.0	COG0477@1|root,COG2814@2|Bacteria,1MUZ8@1224|Proteobacteria,2VI8P@28216|Betaproteobacteria,2KVCT@206389|Rhodocyclales	206389|Rhodocyclales	EGP	Acetyl-coenzyme A transporter 1	ampG	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
k59_230794_1	1165841.SULAR_05323	1.98e-132	388.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,42M48@68525|delta/epsilon subdivisions,2YMM2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
k59_230794_2	1165841.SULAR_05328	3.12e-82	246.0	COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,42MEH@68525|delta/epsilon subdivisions,2YMFC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
k59_1228989_1	944546.ABED_0878	5.36e-23	105.0	COG4254@1|root,COG4254@2|Bacteria,1NBPR@1224|Proteobacteria,42SEW@68525|delta/epsilon subdivisions,2YPKM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
k59_527830_1	747.DR93_374	2.53e-46	162.0	COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,1RZG1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k59_1406245_1	1123368.AUIS01000018_gene743	6.9e-73	228.0	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,1RMAT@1236|Gammaproteobacteria,2NCGB@225057|Acidithiobacillales	1236|Gammaproteobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
k59_750496_1	159087.Daro_0254	1.13e-143	409.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2VHET@28216|Betaproteobacteria,2KUVN@206389|Rhodocyclales	206389|Rhodocyclales	E	ABC-type branched-chain amino acid transport systems, ATPase component	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
k59_1698937_1	709032.Sulku_0061	3.58e-135	388.0	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,42M0U@68525|delta/epsilon subdivisions,2YNJV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	mechanosensitive ion channel	mscS	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
k59_1698937_2	326298.Suden_0046	1.67e-20	90.9	COG3137@1|root,COG3137@2|Bacteria,1PWI2@1224|Proteobacteria,42W3Z@68525|delta/epsilon subdivisions,2YQX2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Protein of unknown function, DUF481	-	-	-	ko:K07283	-	-	-	-	ko00000	-	-	-	DUF481
k59_465711_1	709032.Sulku_2521	1.63e-142	407.0	COG0694@1|root,COG0822@1|root,COG0694@2|Bacteria,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,42MT6@68525|delta/epsilon subdivisions,2YMXY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CO	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins	iscU	-	-	ko:K13819	-	-	-	-	ko00000	-	-	-	Fer2_BFD,NifU,NifU_N
k59_465711_2	1249480.B649_06475	1.26e-119	350.0	COG1639@1|root,COG1639@2|Bacteria,1RAH3@1224|Proteobacteria,42PRF@68525|delta/epsilon subdivisions,2YMRX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Signal transduction protein	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_230876_1	666685.R2APBS1_2466	2.56e-94	283.0	COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,1RMC5@1236|Gammaproteobacteria,1X36N@135614|Xanthomonadales	135614|Xanthomonadales	V	Multidrug ABC transporter ATP-binding protein	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_938927_1	1121035.AUCH01000002_gene1470	7.03e-87	264.0	COG0437@1|root,COG0437@2|Bacteria,1N9WY@1224|Proteobacteria,2VKT4@28216|Betaproteobacteria,2KUVH@206389|Rhodocyclales	206389|Rhodocyclales	C	MauM NapG family ferredoxin-type protein	napG	-	-	ko:K02573	-	-	-	-	ko00000	-	-	-	Fer4_4,Fer4_7
k59_1814068_1	1249480.B649_08065	1.26e-105	314.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,42M54@68525|delta/epsilon subdivisions,2YNPD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	COG0436 Aspartate tyrosine aromatic aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
k59_1814068_2	709032.Sulku_0805	5.91e-07	48.9	2AIWB@1|root,319DT@2|Bacteria,1Q2F3@1224|Proteobacteria,42VJD@68525|delta/epsilon subdivisions,2YQCE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_404963_1	1537917.JU82_06380	2e-81	251.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,42PCH@68525|delta/epsilon subdivisions,2YN62@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	3-deoxy-d-manno-octulosonic-acid transferase	kdtA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	iIT341.HP0957	Glycos_transf_N
k59_465767_1	713587.THITH_10935	1.52e-103	311.0	COG0446@1|root,COG0446@2|Bacteria,1QA17@1224|Proteobacteria,1RSA6@1236|Gammaproteobacteria,1WXMR@135613|Chromatiales	135613|Chromatiales	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_527970_1	550540.Fbal_0023	1.82e-51	169.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,1S247@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0008463,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043021,GO:0043022,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046872,GO:0046914,GO:0071704,GO:1901564	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
k59_759899_1	387093.SUN_1071	2.12e-80	249.0	COG0577@1|root,COG0577@2|Bacteria,1QT4V@1224|Proteobacteria,42P7K@68525|delta/epsilon subdivisions,2YNGD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	ABC transporter permease	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
k59_57185_1	1165841.SULAR_03477	4.7e-97	305.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,42MW3@68525|delta/epsilon subdivisions,2YMT6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
k59_760000_1	709032.Sulku_1571	2.55e-103	305.0	COG0688@1|root,COG0688@2|Bacteria,1MVT4@1224|Proteobacteria,42PAW@68525|delta/epsilon subdivisions,2YNM3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
k59_116346_1	1249480.B649_01005	1.26e-17	84.0	2C99Z@1|root,2Z9YV@2|Bacteria,1N0B7@1224|Proteobacteria,42P3M@68525|delta/epsilon subdivisions,2YMWY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF3373)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3373
k59_116360_1	1249480.B649_08105	1.4e-106	335.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YM7R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Efflux pump membrane transporter	-	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_57364_1	709032.Sulku_0106	4.91e-87	257.0	COG0597@1|root,COG0597@2|Bacteria,1Q1GU@1224|Proteobacteria,42TMD@68525|delta/epsilon subdivisions,2YPZS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
k59_116389_2	709032.Sulku_2085	3.54e-31	114.0	2BR51@1|root,32K31@2|Bacteria,1Q8HX@1224|Proteobacteria,433KM@68525|delta/epsilon subdivisions,2YSI4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1134208_1	765914.ThisiDRAFT_2775	2.74e-15	80.1	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,1SMT1@1236|Gammaproteobacteria,1X0JW@135613|Chromatiales	135613|Chromatiales	T	Response regulator receiver domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,Response_reg
k59_1545600_1	1165841.SULAR_03562	1.72e-29	108.0	COG1550@1|root,COG1550@2|Bacteria,1Q2MJ@1224|Proteobacteria,42VYB@68525|delta/epsilon subdivisions,2YQ9J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
k59_1545600_2	945713.IALB_1794	1.92e-13	67.0	COG2062@1|root,COG2062@2|Bacteria	2|Bacteria	T	phosphohistidine phosphatase, SixA	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
k59_1134214_1	1537917.JU82_02010	1.18e-47	159.0	COG3338@1|root,COG3338@2|Bacteria,1PEA6@1224|Proteobacteria,42RBG@68525|delta/epsilon subdivisions,2YP5T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	carbonic anhydrase	cah	-	4.2.1.1	ko:K01674	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Carb_anhydrase
k59_897094_1	1165841.SULAR_06838	7.31e-71	234.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2YMW4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_1252478_1	159087.Daro_1075	6.24e-55	175.0	COG1950@1|root,COG1950@2|Bacteria,1N1DF@1224|Proteobacteria,2VUY1@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM Membrane protein of	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
k59_1252478_2	159087.Daro_1074	4.07e-13	67.8	COG2816@1|root,COG2816@2|Bacteria,1QGCX@1224|Proteobacteria,2VQIR@28216|Betaproteobacteria,2KW28@206389|Rhodocyclales	206389|Rhodocyclales	L	NADH pyrophosphatase-like rudimentary NUDIX domain	-	-	3.6.1.22	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	-	R00103,R03004,R11104	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,NUDIX-like,zf-NADH-PPase
k59_1545618_2	709032.Sulku_0596	9.35e-138	397.0	COG2041@1|root,COG2041@2|Bacteria,1MX9E@1224|Proteobacteria,42QKD@68525|delta/epsilon subdivisions,2YNHF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Sulfite dehydrogenase (Cytochrome) subunit SorA apoprotein	sorA	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Mo-co_dimer,Oxidored_molyb
k59_1134231_1	159087.Daro_1477	4.45e-102	301.0	COG2005@1|root,COG3585@1|root,COG2005@2|Bacteria,COG3585@2|Bacteria,1P9SX@1224|Proteobacteria,2VMCH@28216|Betaproteobacteria,2KUFB@206389|Rhodocyclales	206389|Rhodocyclales	H	TOBE domain	-	-	-	ko:K02019	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,TOBE
k59_251351_1	1123517.JOMR01000001_gene1832	7.83e-160	471.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,1RNRX@1236|Gammaproteobacteria,45ZT3@72273|Thiotrichales	72273|Thiotrichales	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
k59_716898_1	1165841.SULAR_10689	2.03e-106	318.0	COG2041@1|root,COG2041@2|Bacteria,1MX9E@1224|Proteobacteria,42PRR@68525|delta/epsilon subdivisions,2YMYP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	sulfur dehydrogenase subunit	soxC	-	-	ko:K17225	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	Mo-co_dimer,Oxidored_molyb
k59_1366215_1	387093.SUN_1683	1.48e-184	530.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,42MUY@68525|delta/epsilon subdivisions,2YMZF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	PFAM peptidase M3A and M3B thimet oligopeptidase F	prlC	-	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
k59_1427796_1	709032.Sulku_1645	2.64e-18	81.3	COG1651@1|root,COG1651@2|Bacteria,1Q684@1224|Proteobacteria,432K4@68525|delta/epsilon subdivisions,2YSQB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1427796_2	709032.Sulku_1646	4.91e-12	67.4	COG1033@1|root,COG1033@2|Bacteria	2|Bacteria	S	growth of symbiont in host cell	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_251366_2	159087.Daro_1482	6.91e-63	192.0	2ENZ5@1|root,3190R@2|Bacteria,1Q1CG@1224|Proteobacteria,2W6HI@28216|Betaproteobacteria,2KZNN@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1427819_1	387093.SUN_0634	1.14e-49	166.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,42M84@68525|delta/epsilon subdivisions,2YN32@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
k59_1427819_2	1165841.SULAR_00415	1.97e-70	220.0	COG1651@1|root,COG1651@2|Bacteria,1RFRJ@1224|Proteobacteria,42SPD@68525|delta/epsilon subdivisions,2YP88@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
k59_1018024_1	709032.Sulku_1447	3.12e-187	529.0	COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,42KZP@68525|delta/epsilon subdivisions,2YMBP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG1055 Na H antiporter NhaD and related arsenite	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
k59_1252551_1	583345.Mmol_1188	1.14e-128	375.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2VI01@28216|Betaproteobacteria,2KKCB@206350|Nitrosomonadales	206350|Nitrosomonadales	E	PFAM Aminotransferase class I and II	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_1718518_1	159087.Daro_0970	7.83e-113	336.0	COG3437@1|root,COG3437@2|Bacteria,1P1A3@1224|Proteobacteria,2VIT3@28216|Betaproteobacteria,2KUC5@206389|Rhodocyclales	206389|Rhodocyclales	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD_5,Response_reg
k59_1545694_1	1304883.KI912532_gene612	7.29e-104	310.0	COG1835@1|root,COG1835@2|Bacteria,1NSVZ@1224|Proteobacteria,2VKZ5@28216|Betaproteobacteria,2KW1B@206389|Rhodocyclales	206389|Rhodocyclales	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
k59_367076_1	1537917.JU82_10735	1.77e-142	406.0	COG0287@1|root,COG0287@2|Bacteria,1QTZA@1224|Proteobacteria,42MH0@68525|delta/epsilon subdivisions,2YMHS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
k59_191130_1	760154.Sulba_0821	3.26e-39	140.0	COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,42NHY@68525|delta/epsilon subdivisions,2YRCH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
k59_1427885_1	754436.JCM19237_4164	5.98e-39	143.0	COG3637@1|root,COG3637@2|Bacteria,1RHUP@1224|Proteobacteria,1S8C4@1236|Gammaproteobacteria,1XV1Q@135623|Vibrionales	135623|Vibrionales	M	Domain of unknown function (DUF3943)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3943
k59_1545728_1	398767.Glov_3446	6.42e-42	149.0	COG1639@1|root,COG1639@2|Bacteria,1RAH3@1224|Proteobacteria,42PRF@68525|delta/epsilon subdivisions,2WPR9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM Metal-dependent hydrolase HDOD	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_1718559_1	525254.HMPREF0072_1314	6.33e-05	44.3	COG1694@1|root,COG1694@2|Bacteria	2|Bacteria	FG	Mazg nucleotide pyrophosphohydrolase	mazG	-	-	-	-	-	-	-	-	-	-	-	MazG
k59_1718559_2	1402875.U3TJZ9_9CAUD	6.53e-47	160.0	4QARC@10239|Viruses,4QV4E@35237|dsDNA viruses  no RNA stage,4QPDS@28883|Caudovirales,4QP0H@10744|Podoviridae	10744|Podoviridae	S	nucleic acid binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1252608_1	582744.Msip34_1323	8.22e-47	156.0	COG2259@1|root,COG2259@2|Bacteria,1RM2W@1224|Proteobacteria,2VWVB@28216|Betaproteobacteria,2KMYZ@206350|Nitrosomonadales	206350|Nitrosomonadales	S	PFAM DoxX family protein	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
k59_1777351_1	1254432.SCE1572_43590	9.75e-14	79.0	COG0642@1|root,COG2203@1|root,COG3437@1|root,COG3899@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3437@2|Bacteria,COG3899@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WKF3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF_2,HATPase_c,HisKA,PAS_4,Pkinase,Response_reg
k59_1601137_1	1165841.SULAR_06638	4.02e-28	107.0	COG0681@1|root,COG0681@2|Bacteria,1QENE@1224|Proteobacteria,42ZRJ@68525|delta/epsilon subdivisions,2YRPB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Peptidase S24-like	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
k59_1601137_2	709032.Sulku_0527	1e-70	216.0	2E6EV@1|root,3312A@2|Bacteria,1N8Q0@1224|Proteobacteria,42WW1@68525|delta/epsilon subdivisions,2YRZ8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PgaD-like protein	-	-	-	ko:K11937	ko02026,map02026	-	-	-	ko00000,ko00001	-	-	-	PgaD
k59_488486_1	1304888.ATWF01000001_gene1244	1.57e-49	177.0	COG5001@1|root,COG5001@2|Bacteria,2GGQI@200930|Deferribacteres	2|Bacteria	T	Double sensory domain of two-component sensor kinase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,FIST,FIST_C,GGDEF,dCache_1,dCache_2,dCache_3
k59_1548918_2	709032.Sulku_0640	3.76e-161	450.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42M6H@68525|delta/epsilon subdivisions,2YNC6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	4Fe-4S ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11,Fer4_4
k59_1192583_1	292563.Cyast_2140	7.72e-34	135.0	COG0515@1|root,COG2199@1|root,COG2203@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,1GBKM@1117|Cyanobacteria	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GGDEF,HATPase_c,HisKA,PAS_3,PAS_4,Pkinase,Response_reg,SpoIIE
k59_899830_1	1144325.PMI22_05756	1.85e-72	237.0	COG2199@1|root,COG3614@1|root,COG2199@2|Bacteria,COG3614@2|Bacteria,1RDM8@1224|Proteobacteria	1224|Proteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GGDEF
k59_429537_1	1249480.B649_00260	7.25e-33	129.0	COG3144@1|root,COG3144@2|Bacteria,1PBUJ@1224|Proteobacteria,42VQM@68525|delta/epsilon subdivisions,2YQGT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Flagellar hook-length control protein FliK	-	-	-	-	-	-	-	-	-	-	-	-	Flg_hook
k59_1721530_1	709032.Sulku_1608	8.1e-78	250.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1R5RS@1224|Proteobacteria,42M3K@68525|delta/epsilon subdivisions,2YN6E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	PFAM biotin lipoyl attachment domain-containing protein	pycB	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
k59_1192600_1	395494.Galf_1734	3.27e-30	114.0	COG1562@1|root,COG1562@2|Bacteria,1MX4W@1224|Proteobacteria,2VJ13@28216|Betaproteobacteria,44V7C@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Squalene/phytoene synthase	hpnD	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
k59_1603710_1	380703.AHA_0191	2.18e-09	58.9	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,1RNS2@1236|Gammaproteobacteria,1Y41T@135624|Aeromonadales	135624|Aeromonadales	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	fieF	-	-	ko:K13283	-	-	-	-	ko00000,ko02000	2.A.4.7.1	-	-	Cation_efflux,ZT_dimer
k59_1603710_2	713587.THITH_01315	2.71e-39	137.0	COG2518@1|root,COG2518@2|Bacteria,1RD6S@1224|Proteobacteria,1S0KH@1236|Gammaproteobacteria,1WX4D@135613|Chromatiales	135613|Chromatiales	O	PFAM protein-L-isoaspartate(D-aspartate) O-methyltransferase	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
k59_491387_1	159087.Daro_1050	8.2e-81	243.0	COG0589@1|root,COG0589@2|Bacteria,1N8EJ@1224|Proteobacteria,2VUAF@28216|Betaproteobacteria,2KX5X@206389|Rhodocyclales	206389|Rhodocyclales	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_1548970_1	1249480.B649_01545	1.97e-102	301.0	COG0847@1|root,COG0847@2|Bacteria,1PDD1@1224|Proteobacteria,42MUX@68525|delta/epsilon subdivisions,2YNB6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG0847 DNA polymerase III epsilon subunit and related 3'-5'	-	-	2.7.7.7	ko:K02342,ko:K10857	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_18790_1	1537917.JU82_08325	8.21e-119	342.0	COG0302@1|root,COG0302@2|Bacteria,1MY3N@1224|Proteobacteria,42N1U@68525|delta/epsilon subdivisions,2YMVV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	GTP cyclohydrolase	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0928	GTP_cyclohydroI
k59_18790_2	1121403.AUCV01000025_gene2272	2.96e-18	79.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,42SBD@68525|delta/epsilon subdivisions,2WP9P@28221|Deltaproteobacteria,2MKCX@213118|Desulfobacterales	28221|Deltaproteobacteria	J	PFAM ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
k59_607474_1	317025.Tcr_0117	5.09e-23	97.4	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,1RN6I@1236|Gammaproteobacteria,45ZWG@72273|Thiotrichales	72273|Thiotrichales	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,HemN_C,Radical_SAM
k59_607474_2	1123257.AUFV01000003_gene1225	2.97e-71	226.0	COG0127@1|root,COG0454@1|root,COG0127@2|Bacteria,COG0456@2|Bacteria,1MUK5@1224|Proteobacteria,1S27C@1236|Gammaproteobacteria,1X4DK@135614|Xanthomonadales	135614|Xanthomonadales	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Ham1p_like
k59_607474_3	471881.PROPEN_00764	2e-57	186.0	COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,1RNTB@1236|Gammaproteobacteria,3Z1G5@583|Proteus	1236|Gammaproteobacteria	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
k59_551726_2	1249480.B649_00115	5.27e-37	129.0	2BSDP@1|root,32MFN@2|Bacteria,1Q399@1224|Proteobacteria,42Y0H@68525|delta/epsilon subdivisions,2YQR2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1663355_1	1150626.PHAMO_210046	2.17e-20	97.4	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,2JQMP@204441|Rhodospirillales	204441|Rhodospirillales	OQ	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
k59_899888_1	1537917.JU82_04980	2.96e-105	316.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,42N4K@68525|delta/epsilon subdivisions,2YMXB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
k59_1549024_1	387093.SUN_0555	5.33e-10	60.1	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MA6@68525|delta/epsilon subdivisions,2YMMG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	COG0841 Cation multidrug efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1549024_2	387093.SUN_0554	8.57e-78	247.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MQ0@68525|delta/epsilon subdivisions,2YN57@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1255935_1	1249480.B649_07510	2.08e-182	532.0	COG5001@1|root,COG5001@2|Bacteria,1R4H0@1224|Proteobacteria,43CII@68525|delta/epsilon subdivisions,2YTD5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_139421_1	159087.Daro_3006	1.25e-94	309.0	COG0517@1|root,COG0642@1|root,COG0784@1|root,COG2198@1|root,COG2202@1|root,COG2203@1|root,COG0517@2|Bacteria,COG0642@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,1NC9X@1224|Proteobacteria,2WGIN@28216|Betaproteobacteria,2KZWQ@206389|Rhodocyclales	206389|Rhodocyclales	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	CBS,GAF_2,HATPase_c,HisKA,Hpt,PAS_3,Response_reg
k59_1549049_2	1121035.AUCH01000007_gene552	1.82e-48	155.0	COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,2VTYP@28216|Betaproteobacteria,2KWWW@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
k59_1549049_3	1304883.KI912532_gene3072	1.27e-34	122.0	COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,2VQ0H@28216|Betaproteobacteria,2KWFJ@206389|Rhodocyclales	206389|Rhodocyclales	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
k59_1663409_1	387093.SUN_1315	1.91e-88	284.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2YMQV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_1842729_1	937774.TEQUI_0215	5.41e-10	66.6	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,2VHHA@28216|Betaproteobacteria,3T2NZ@506|Alcaligenaceae	28216|Betaproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
k59_1487513_1	76114.ebA935	2.36e-148	428.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,2VJD7@28216|Betaproteobacteria,2KVIA@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k59_719066_1	1537917.JU82_03895	7.84e-48	164.0	COG1413@1|root,COG1413@2|Bacteria,1Q1TE@1224|Proteobacteria,42UC8@68525|delta/epsilon subdivisions,2YPXK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_719066_2	1249480.B649_01550	1.24e-30	109.0	COG0790@1|root,COG0790@2|Bacteria	2|Bacteria	S	beta-lactamase activity	enhC	-	-	ko:K07126,ko:K15474	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	Sel1
k59_551812_1	946483.Cenrod_2638	4.99e-05	52.4	COG3614@1|root,COG4251@1|root,COG3614@2|Bacteria,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_9,Phosphonate-bd,Protoglobin,Response_reg
k59_1021823_1	1165841.SULAR_02543	2.02e-66	213.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,42N4K@68525|delta/epsilon subdivisions,2YMXB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
k59_1021823_2	1165841.SULAR_02528	1.36e-108	323.0	COG0500@1|root,COG2226@2|Bacteria,1NV27@1224|Proteobacteria,42P39@68525|delta/epsilon subdivisions,2YNRW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
k59_1021826_1	749222.Nitsa_0039	2.92e-16	82.4	COG0791@1|root,COG1388@1|root,COG0791@2|Bacteria,COG1388@2|Bacteria,1N0EE@1224|Proteobacteria,43AQ7@68525|delta/epsilon subdivisions,2YSYN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM,NLPC_P60
k59_1603822_1	1168034.FH5T_09810	1.04e-35	133.0	COG0109@1|root,COG0109@2|Bacteria,4NF5A@976|Bacteroidetes	976|Bacteroidetes	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
k59_960239_1	614083.AWQR01000021_gene220	4.89e-134	389.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,2VHAP@28216|Betaproteobacteria,4ABVH@80864|Comamonadaceae	28216|Betaproteobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
k59_781358_2	709032.Sulku_0350	2.16e-112	332.0	COG0628@1|root,COG0628@2|Bacteria,1PMAR@1224|Proteobacteria,42TGZ@68525|delta/epsilon subdivisions,2YR9I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k59_1842770_1	987059.RBXJA2T_00230	2.39e-89	278.0	COG0433@1|root,COG0433@2|Bacteria,1MU59@1224|Proteobacteria,2VIJY@28216|Betaproteobacteria,1KJ6Y@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Bacterial protein of unknown function (DUF853)	yjgR	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853
k59_1076959_2	709032.Sulku_0930	6.86e-90	266.0	COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,42QQ4@68525|delta/epsilon subdivisions,2YNX7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	iIT341.HP1016	CDP-OH_P_transf
k59_551849_1	159087.Daro_1463	1.6e-95	285.0	COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,2VHZU@28216|Betaproteobacteria,2KVHR@206389|Rhodocyclales	206389|Rhodocyclales	H	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
k59_1192738_2	1249480.B649_10125	4.94e-81	243.0	COG0252@1|root,COG0252@2|Bacteria,1RHAW@1224|Proteobacteria,42SNH@68525|delta/epsilon subdivisions,2YQ20@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EJ	GlutRNAGln amidotransferase subunit D	-	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
k59_719096_1	1144325.PMI22_06032	0.000244	47.8	COG1729@1|root,COG1729@2|Bacteria	2|Bacteria	S	protein trimerization	cpoB	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	TPR_16,TPR_6,TolA_bind_tri,YfiO
k59_369621_1	267608.RSc2530	2.43e-10	62.4	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,2VHPG@28216|Betaproteobacteria,1K28I@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
k59_369621_2	159087.Daro_3209	2.24e-53	170.0	COG0848@1|root,COG0848@2|Bacteria,1N0ZA@1224|Proteobacteria,2VUF4@28216|Betaproteobacteria,2KWV6@206389|Rhodocyclales	206389|Rhodocyclales	U	Biopolymer transport protein	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
k59_960278_1	1304883.KI912532_gene654	9.04e-62	209.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,2VH4X@28216|Betaproteobacteria,2KUPP@206389|Rhodocyclales	206389|Rhodocyclales	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_429693_1	1415778.JQMM01000001_gene1688	1.07e-19	92.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1RGKE@1224|Proteobacteria,1T3HV@1236|Gammaproteobacteria,1J639@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF,PAS_3
k59_491550_1	190486.XAC0063	8.41e-29	114.0	28N1N@1|root,2ZB7Q@2|Bacteria,1R86T@1224|Proteobacteria,1T2XG@1236|Gammaproteobacteria,1X7YK@135614|Xanthomonadales	135614|Xanthomonadales	H	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1
k59_310280_2	159087.Daro_3659	3.42e-173	507.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,2VIJ7@28216|Betaproteobacteria,2KVBE@206389|Rhodocyclales	206389|Rhodocyclales	M	Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_C
k59_1842843_3	1249480.B649_01080	2.96e-131	379.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,42MVI@68525|delta/epsilon subdivisions,2YMGY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	aldo keto reductase	tas	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_1663513_1	326298.Suden_1213	4.67e-46	161.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,42QN4@68525|delta/epsilon subdivisions,2YTQA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_1050260_2	1165841.SULAR_00185	8.82e-16	77.4	COG1538@1|root,COG1538@2|Bacteria,1Q066@1224|Proteobacteria,42RNJ@68525|delta/epsilon subdivisions,2YNZR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_1163072_1	1249480.B649_10585	1.58e-88	275.0	COG4972@1|root,COG4972@2|Bacteria,1PZTK@1224|Proteobacteria,42R44@68525|delta/epsilon subdivisions,2YP2H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Pilus assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1868652_1	709032.Sulku_0030	1.48e-81	251.0	COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,42R7K@68525|delta/epsilon subdivisions,2YP16@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
k59_1282784_1	1502770.JQMG01000001_gene1160	5.97e-13	63.2	COG0185@1|root,COG0185@2|Bacteria,1RGYX@1224|Proteobacteria,2VSGE@28216|Betaproteobacteria,2KMZZ@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
k59_1282784_2	1132855.KB913035_gene2490	2.34e-87	262.0	COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,2VHSD@28216|Betaproteobacteria,2KM4M@206350|Nitrosomonadales	206350|Nitrosomonadales	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
k59_1577119_1	709032.Sulku_0572	1.42e-125	381.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,42M9S@68525|delta/epsilon subdivisions,2YMAH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the ClpA ClpB family	clpB	-	-	ko:K03694,ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_163165_1	709032.Sulku_1859	6.97e-78	243.0	COG0167@1|root,COG0167@2|Bacteria,1MXER@1224|Proteobacteria,42QNP@68525|delta/epsilon subdivisions,2YR5C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
k59_1332299_1	1442598.JABW01000022_gene1997	2.08e-40	139.0	COG2862@1|root,COG2862@2|Bacteria,1RFUX@1224|Proteobacteria,42T0B@68525|delta/epsilon subdivisions,2YP5M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	UPF0114
k59_163185_2	1537917.JU82_09115	2.1e-70	219.0	COG1792@1|root,COG1792@2|Bacteria,1QB26@1224|Proteobacteria,42MF4@68525|delta/epsilon subdivisions,2YNT9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Rod shape-determining protein MreC	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
k59_219936_1	1150621.SMUL_0403	9.95e-92	278.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,42MV9@68525|delta/epsilon subdivisions,2YMPG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
k59_275665_2	1286093.C266_02511	8.06e-17	76.3	2EPS6@1|root,33HCQ@2|Bacteria,1NJVM@1224|Proteobacteria,2VY9X@28216|Betaproteobacteria,1KEU0@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_39114_1	395494.Galf_2693	6.16e-116	350.0	COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,2VHHJ@28216|Betaproteobacteria,44VEJ@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Hsp90 protein	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
k59_1509593_1	883126.HMPREF9710_04026	4.59e-67	215.0	COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,2VIJH@28216|Betaproteobacteria,473BM@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	NMT1-like family	nasF	-	-	ko:K02051,ko:K15576,ko:K22067	ko00910,ko02010,map00910,map02010	M00188,M00438	-	-	ko00000,ko00001,ko00002,ko02000,ko02022	3.A.1.16,3.A.1.16.1,3.A.1.16.2,3.A.1.17	-	-	NMT1_2
k59_737986_1	75379.Tint_3042	8.66e-67	216.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,2VMHH@28216|Betaproteobacteria,1KKKA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	TIGRFAM cation diffusion facilitator family transporter	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux,ZT_dimer
k59_737986_2	414684.RC1_2249	1.92e-15	74.7	COG2908@1|root,COG2908@2|Bacteria,1MVKD@1224|Proteobacteria,2TSEB@28211|Alphaproteobacteria,2JQH4@204441|Rhodospirillales	204441|Rhodospirillales	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
k59_1577203_1	748247.AZKH_p0398	1.48e-05	53.5	COG2199@1|root,COG3290@1|root,COG2199@2|Bacteria,COG3290@2|Bacteria,1RGCV@1224|Proteobacteria,2W303@28216|Betaproteobacteria	28216|Betaproteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CHASE,EAL,GGDEF,MASE1,PAS,PAS_4,PAS_9,dCache_1
k59_1868726_1	1538295.JY96_10650	3.18e-50	173.0	COG0644@1|root,COG0644@2|Bacteria,1MXQY@1224|Proteobacteria,2VTTR@28216|Betaproteobacteria,1KIVH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Tryptophan halogenase	-	-	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_3
k59_1216572_1	1537917.JU82_06325	9.74e-36	128.0	COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,42MJU@68525|delta/epsilon subdivisions,2YM7H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	UTP-glucose-1-phosphate uridylyltransferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0646	NTP_transferase
k59_1216572_2	1249480.B649_08850	3.37e-85	266.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,42MPH@68525|delta/epsilon subdivisions,2YMZ9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	N-acetylmuramoyl-L-alanine amidase	amiA	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
k59_1332341_1	326298.Suden_0930	9.22e-54	189.0	COG1234@1|root,COG2203@1|root,COG2206@1|root,COG3437@1|root,COG1234@2|Bacteria,COG2203@2|Bacteria,COG2206@2|Bacteria,COG3437@2|Bacteria,1MV37@1224|Proteobacteria,42N4N@68525|delta/epsilon subdivisions,2YNBF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	cAMP phosphodiesterases class-II	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HD,HD_5,Lactamase_B_2,PDEase_II
k59_1685605_1	1265313.HRUBRA_00265	6.39e-23	96.7	COG1960@1|root,COG1960@2|Bacteria,1MU2V@1224|Proteobacteria,1RNJH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_1868744_1	1120977.JHUX01000003_gene623	0.000209	50.1	COG4222@1|root,COG4222@2|Bacteria,1MVDD@1224|Proteobacteria,1RYXE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Esterase-like activity of phytase	-	-	-	-	-	-	-	-	-	-	-	-	Phytase-like
k59_1628485_1	243164.DET0625	8.08e-09	63.9	COG4191@1|root,COG4191@2|Bacteria,2G6UY@200795|Chloroflexi,34D87@301297|Dehalococcoidia	301297|Dehalococcoidia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
k59_1216599_1	158822.LH89_13360	9.24e-09	61.6	COG0840@1|root,COG0840@2|Bacteria	2|Bacteria	NT	transmembrane signaling receptor activity	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,MCPsignal
k59_329970_1	709032.Sulku_2174	1.13e-86	265.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,42MGU@68525|delta/epsilon subdivisions,2YMB7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
k59_808841_1	709032.Sulku_2347	7.62e-183	511.0	COG2010@1|root,COG2010@2|Bacteria,1PDTK@1224|Proteobacteria,42N5Z@68525|delta/epsilon subdivisions,2YMTR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
k59_808841_2	1249480.B649_11120	1.97e-32	113.0	COG4736@1|root,COG4736@2|Bacteria,1QDIU@1224|Proteobacteria,42V2T@68525|delta/epsilon subdivisions,2YQ9S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	cytochrome c oxidase	ccoQ	-	-	ko:K00407	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixQ
k59_1802209_2	709032.Sulku_1660	5.68e-08	56.6	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42N03@68525|delta/epsilon subdivisions,2YNMG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	PFAM Methyl-accepting chemotaxis protein (MCP) signaling domain	-	-	-	ko:K03406,ko:K05875	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,MCPsignal
k59_1685626_1	1249480.B649_09815	5.18e-70	211.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,42SJJ@68525|delta/epsilon subdivisions,2YPEW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Belongs to the P(II) protein family	glnB	-	-	ko:K04751,ko:K04752	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
k59_1802216_1	1249480.B649_08705	1.07e-123	357.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,42MUR@68525|delta/epsilon subdivisions,2YMG3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
k59_1216622_1	371731.Rsw2DRAFT_2503	5.62e-26	108.0	COG2244@1|root,COG2244@2|Bacteria,1MWKV@1224|Proteobacteria,2TTYS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Membrane protein involved in the export of O-antigen and teichoic acid	MA20_18165	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
k59_1628514_1	640081.Dsui_0949	5.81e-42	138.0	COG3530@1|root,COG3530@2|Bacteria,1N7GT@1224|Proteobacteria,2VW2G@28216|Betaproteobacteria,2KXD0@206389|Rhodocyclales	206389|Rhodocyclales	S	Putative quorum-sensing-regulated virulence factor	-	-	-	ko:K09954	-	-	-	-	ko00000	-	-	-	QSregVF_b
k59_1163217_1	580332.Slit_2851	9.1e-12	67.8	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,2VI8I@28216|Betaproteobacteria,44VF5@713636|Nitrosomonadales	28216|Betaproteobacteria	CO	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_2,Thioredoxin_7
k59_1163217_2	395494.Galf_2877	2.3e-36	125.0	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,2VUC8@28216|Betaproteobacteria,44VZ7@713636|Nitrosomonadales	28216|Betaproteobacteria	P	PFAM CutA1 divalent ion tolerance protein	cutA	GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
k59_393228_1	75379.Tint_0587	8.52e-56	184.0	COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,2VHPJ@28216|Betaproteobacteria,1KM4J@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Transporter	-	-	-	ko:K11688,ko:K21395	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctP
k59_1512669_1	1448857.JFAP01000004_gene847	0.000323	42.7	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,42PQP@68525|delta/epsilon subdivisions,2YNQ7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	abc transporter atp-binding protein	ybbA	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_1512669_2	1537917.JU82_10765	1.85e-119	346.0	COG1684@1|root,COG1684@2|Bacteria,1NIF4@1224|Proteobacteria,42NX7@68525|delta/epsilon subdivisions,2YMKE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Flagellar biosynthetic protein fliR	fliR	-	-	ko:K02421	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1
k59_332966_1	90813.JQMT01000001_gene1978	2.71e-21	99.0	COG0840@1|root,COG5002@1|root,COG0840@2|Bacteria,COG5002@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,461EP@72273|Thiotrichales	72273|Thiotrichales	T	Methyl-accepting chemotaxis protein (MCP) signaling domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,CZB,MCPsignal,PAS_3,PAS_8,PAS_9
k59_1166432_1	1504672.669783682	6.46e-110	334.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VI4Q@28216|Betaproteobacteria,4A9SZ@80864|Comamonadaceae	28216|Betaproteobacteria	O	Belongs to the peptidase S1C family	mucD	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
k59_581441_1	159087.Daro_2801	3.3e-112	354.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2VHCZ@28216|Betaproteobacteria,2KVY2@206389|Rhodocyclales	206389|Rhodocyclales	P	AcrB/AcrD/AcrF family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
k59_1053430_1	997884.HMPREF1068_03804	1.46e-78	255.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,4NFUJ@976|Bacteroidetes,2FM2T@200643|Bacteroidia,4AKYC@815|Bacteroidaceae	976|Bacteroidetes	C	Psort location Cytoplasmic, score	maeB	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
k59_636674_1	159087.Daro_1988	1.23e-22	102.0	COG4191@1|root,COG5001@1|root,COG4191@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_636674_2	292415.Tbd_1198	4.98e-13	67.0	2BZ72@1|root,32Z0T@2|Bacteria,1NBTY@1224|Proteobacteria,2VX7F@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1804992_1	387093.SUN_0459	1.22e-84	260.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,42MMY@68525|delta/epsilon subdivisions,2YMDM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	dihydropteroate synthase	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
k59_455402_2	1537917.JU82_08260	7.2e-33	115.0	2BT0G@1|root,32N4I@2|Bacteria,1Q3JR@1224|Proteobacteria,432I1@68525|delta/epsilon subdivisions,2YSVN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_581465_1	1249480.B649_09090	5.42e-43	148.0	28M05@1|root,2ZAF9@2|Bacteria,1MY5U@1224|Proteobacteria,42MJP@68525|delta/epsilon subdivisions,2YMVI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	General glycosylation pathway protein	pglG	-	-	-	-	-	-	-	-	-	-	-	dCache_1
k59_1285373_1	1165841.SULAR_06153	4.56e-45	147.0	COG4627@1|root,COG4627@2|Bacteria,1NHR6@1224|Proteobacteria,42VA4@68525|delta/epsilon subdivisions,2YQEV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Stress responsive A B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
k59_1285373_2	387093.SUN_1877	7.5e-116	333.0	COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,42QZJ@68525|delta/epsilon subdivisions,2YNXZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
k59_1285373_3	387093.SUN_1876	1.53e-21	92.0	COG2404@1|root,COG2404@2|Bacteria,1NHB1@1224|Proteobacteria,42NB0@68525|delta/epsilon subdivisions,2YMQ4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	phosphohydrolase (DHH superfamily)	-	-	-	ko:K07097	-	-	-	-	ko00000	-	-	-	DHHA1
k59_991574_1	709032.Sulku_1385	1.21e-128	387.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,42M9Q@68525|delta/epsilon subdivisions,2YNFG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.20.2.1,1.20.9.1,1.7.7.2	ko:K00367,ko:K00372,ko:K08356	ko00910,ko01120,map00910,map01120	M00531	R00791,R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.6	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_41896_1	1537917.JU82_04035	8.63e-80	244.0	COG1639@1|root,COG1639@2|Bacteria,1Q1C5@1224|Proteobacteria,42T98@68525|delta/epsilon subdivisions,2YPNT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_1688624_1	1355374.JARU01000003_gene1157	1.47e-41	157.0	COG5001@1|root,COG5001@2|Bacteria,1R4H0@1224|Proteobacteria,42Q74@68525|delta/epsilon subdivisions,2YMQI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,EAL,GGDEF,PAS_3,PAS_9
k59_41903_3	1304883.KI912532_gene429	5.88e-06	48.5	COG0204@1|root,COG0204@2|Bacteria,1MWDY@1224|Proteobacteria,2VJ4I@28216|Betaproteobacteria,2KV3W@206389|Rhodocyclales	206389|Rhodocyclales	I	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,MFS_1
k59_581518_1	709032.Sulku_1071	1.36e-99	303.0	COG0702@1|root,COG0702@2|Bacteria,1PDTN@1224|Proteobacteria,42M8X@68525|delta/epsilon subdivisions,2YM7Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
k59_1335597_1	709032.Sulku_2099	4.84e-58	194.0	COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,42MCZ@68525|delta/epsilon subdivisions,2YMYT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	type I secretion membrane fusion protein, HlyD family	-	-	-	ko:K12542,ko:K16300	-	M00330,M00571	-	-	ko00000,ko00002,ko02000,ko02044	3.A.1.109.4,8.A.1,8.A.1.3.3	-	-	Biotin_lipoyl_2,HlyD,HlyD_3
k59_740626_1	1168067.JAGP01000001_gene992	8.8e-46	167.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,45ZZR@72273|Thiotrichales	72273|Thiotrichales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_9
k59_991617_1	977880.RALTA_A0539	3.36e-82	271.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,1K044@119060|Burkholderiaceae	28216|Betaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	mdtB	-	-	ko:K03296,ko:K07788,ko:K07789	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	2.A.6.2	-	-	ACR_tran
k59_991617_2	1247649.D560_1925	0.00089	42.4	COG0845@1|root,COG0845@2|Bacteria,1MW65@1224|Proteobacteria,2VHQP@28216|Betaproteobacteria,3T1Q8@506|Alcaligenaceae	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	mdtA	-	-	ko:K07799	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_1103345_1	1502770.JQMG01000001_gene1256	1.49e-95	291.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2VKJI@28216|Betaproteobacteria,2KKMC@206350|Nitrosomonadales	206350|Nitrosomonadales	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_1461534_1	283942.IL0161	1.64e-09	66.2	COG1404@1|root,COG3291@1|root,COG4935@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG4935@2|Bacteria,1MVJE@1224|Proteobacteria,1RQ2M@1236|Gammaproteobacteria,2QF1S@267893|Idiomarinaceae	1236|Gammaproteobacteria	M	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,PA,Peptidase_S8
k59_333144_1	1537917.JU82_03420	1.77e-95	303.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,42KZI@68525|delta/epsilon subdivisions,2YR60@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Domain of unknown function (DUF3458_C) ARM repeats	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,Peptidase_M1
k59_740654_1	530564.Psta_2029	7.35e-40	150.0	COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,2IX1D@203682|Planctomycetes	203682|Planctomycetes	H	May be the GTPase, regulating ATP sulfurylase activity	cysN	GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0044237	2.7.1.25,2.7.7.4	ko:K00955	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU
k59_1219592_1	1296416.JACB01000004_gene1153	2.36e-47	162.0	arCOG10603@1|root,32SV6@2|Bacteria,4NJM3@976|Bacteroidetes,1HXZQ@117743|Flavobacteriia,2YKMX@290174|Aquimarina	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_393513_1	1132855.KB913035_gene752	9.77e-129	384.0	COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,2VITS@28216|Betaproteobacteria,2KKBP@206350|Nitrosomonadales	206350|Nitrosomonadales	L	PFAM DNA photolyase FAD-binding	-	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
k59_1580455_2	159087.Daro_3762	3.05e-29	108.0	2BWQ4@1|root,32QZV@2|Bacteria,1MZQ9@1224|Proteobacteria,2VSNR@28216|Betaproteobacteria,2KWKW@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of unknown function (DUF4124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124
k59_1631546_1	290318.Cvib_0436	1.45e-34	137.0	COG0726@1|root,COG2373@1|root,COG2931@1|root,COG3210@1|root,COG5184@1|root,COG0726@2|Bacteria,COG2373@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	xlnB	GO:0005575,GO:0016020	3.1.4.3,3.2.1.8	ko:K01114,ko:K01181,ko:K12287,ko:K15125	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,ko05133,map00562,map00564,map00565,map01100,map01110,map02024,map04919,map05133	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko00536,ko01000,ko02042,ko02044	-	-	-	CBM60,CBM_6,Glyco_hydro_11,Polysacc_deac_1
k59_1053592_1	1392838.AWNM01000046_gene1934	0.000162	43.9	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,2VHEB@28216|Betaproteobacteria,3T5IW@506|Alcaligenaceae	28216|Betaproteobacteria	E	acetylornithine aminotransferase	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_1053592_2	314285.KT71_07444	7.84e-111	329.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,1RQ59@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3,2.1.3.6,2.1.3.9	ko:K00611,ko:K09065,ko:K13252	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01398,R07245	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k59_1053593_1	1537917.JU82_11790	1.95e-315	871.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2YMHD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA helicase	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_1805138_1	387093.SUN_0708	6.28e-32	113.0	COG0640@1|root,COG0640@2|Bacteria,1NCXP@1224|Proteobacteria,42TJG@68525|delta/epsilon subdivisions,2YPXU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1805138_2	387093.SUN_0709	1.55e-70	216.0	2B0BZ@1|root,31SP3@2|Bacteria,1RM1T@1224|Proteobacteria,42RVA@68525|delta/epsilon subdivisions,2YPBI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1395922_1	1415779.JOMH01000001_gene1180	7.6e-31	123.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,1RN70@1236|Gammaproteobacteria,1X2ZI@135614|Xanthomonadales	135614|Xanthomonadales	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
k59_865750_2	62928.azo2326	4.27e-15	75.5	COG2199@1|root,COG2199@2|Bacteria,1R3XS@1224|Proteobacteria,2VNNY@28216|Betaproteobacteria,2KVXR@206389|Rhodocyclales	206389|Rhodocyclales	T	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HAMP,dCache_1
k59_1688752_1	159087.Daro_3549	3.07e-52	189.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria,2KVXP@206389|Rhodocyclales	206389|Rhodocyclales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,Response_reg
k59_1461612_1	1249480.B649_03965	8.08e-85	271.0	COG1033@1|root,COG1033@2|Bacteria	2|Bacteria	S	growth of symbiont in host cell	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_455568_1	864073.HFRIS_023711	9.28e-67	210.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,2VHSA@28216|Betaproteobacteria,473CE@75682|Oxalobacteraceae	28216|Betaproteobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
k59_455568_2	1304883.KI912532_gene1101	1.45e-11	62.4	COG3150@1|root,COG3150@2|Bacteria,1MVJF@1224|Proteobacteria,2VRCD@28216|Betaproteobacteria,2KWCR@206389|Rhodocyclales	206389|Rhodocyclales	S	Uncharacterised protein family (UPF0227)	-	-	-	ko:K07000	-	-	-	-	ko00000	-	-	-	UPF0227
k59_1053624_1	1165841.SULAR_08909	1.3e-94	305.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,42MWW@68525|delta/epsilon subdivisions,2YMMH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_1631586_1	885272.JonanDRAFT_0227	3.56e-28	106.0	COG1247@1|root,COG1247@2|Bacteria	2|Bacteria	M	phosphinothricin N-acetyltransferase activity	-	-	2.3.1.183,2.3.1.82	ko:K03823,ko:K18816	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	br01600,ko00000,ko00001,ko01000,ko01504	-	-	-	Acetyltransf_1
k59_1631586_2	1537917.JU82_10210	3.99e-62	194.0	2C388@1|root,30ZIR@2|Bacteria,1RFG7@1224|Proteobacteria,42ZDQ@68525|delta/epsilon subdivisions,2YR9C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1580514_1	709032.Sulku_1742	5.51e-94	294.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42PTS@68525|delta/epsilon subdivisions,2YNBM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_1461644_2	1537917.JU82_09340	3.84e-47	155.0	2A1M6@1|root,30PVA@2|Bacteria,1QTJ9@1224|Proteobacteria,42VDW@68525|delta/epsilon subdivisions,2YQIZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
k59_1631613_1	709032.Sulku_0694	5.38e-17	76.3	2B10Q@1|root,319PM@2|Bacteria,1Q3G4@1224|Proteobacteria,42X9K@68525|delta/epsilon subdivisions,2YQYY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1631613_2	709032.Sulku_0695	3.04e-60	190.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,42U1F@68525|delta/epsilon subdivisions,2YP4X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	methyltransferase	rsmD	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth95
k59_1219679_1	460265.Mnod_4345	3.2e-49	179.0	COG1216@1|root,COG1216@2|Bacteria,1MZSD@1224|Proteobacteria,2UBCY@28211|Alphaproteobacteria,1JY92@119045|Methylobacteriaceae	28211|Alphaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_1166755_2	1249480.B649_08845	3.43e-24	97.4	COG3064@1|root,COG3064@2|Bacteria	2|Bacteria	M	translation initiation factor activity	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	Peptidase_M56
k59_770552_1	211586.SO_1038	1.51e-09	64.7	COG1492@1|root,COG1492@2|Bacteria,1MUFY@1224|Proteobacteria,1RP8G@1236|Gammaproteobacteria,2QAY3@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,CbiA,GATase_3
k59_770552_2	944547.ABLL_2451	1.45e-19	90.1	COG0745@1|root,COG0745@2|Bacteria,1PGQP@1224|Proteobacteria,43046@68525|delta/epsilon subdivisions,2YRX3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_243218_1	247639.MGP2080_12998	3.47e-68	233.0	COG4774@1|root,COG4774@2|Bacteria,1QXYG@1224|Proteobacteria	1224|Proteobacteria	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_359952_1	880071.Fleli_3222	5.95e-68	226.0	COG1001@1|root,COG1001@2|Bacteria,4NFD9@976|Bacteroidetes,47KX0@768503|Cytophagia	976|Bacteroidetes	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
k59_538609_1	204536.SULAZ_0730	4.12e-107	339.0	COG3696@1|root,COG3696@2|Bacteria	2|Bacteria	P	silver ion transport	czcA	-	-	ko:K07787,ko:K15726	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.2,2.A.6.1.4	-	-	ACR_tran
k59_831074_1	159087.Daro_0291	3.33e-101	303.0	COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,2VH46@28216|Betaproteobacteria,2KVFQ@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the peptidase S11 family	dacC	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
k59_1182669_2	1174684.EBMC1_08576	1.83e-77	248.0	COG5379@1|root,COG5379@2|Bacteria,1MWG8@1224|Proteobacteria,2TQKH@28211|Alphaproteobacteria,2K195@204457|Sphingomonadales	204457|Sphingomonadales	I	S-adenosylmethionine diacylglycerol 3-amino-3-carboxypropyl transferase	-	-	-	ko:K13622	ko00564,map00564	-	R09072	RC00021,RC01091	ko00000,ko00001	-	-	-	DUF3419
k59_831080_2	1537917.JU82_10895	1.98e-39	131.0	2AITQ@1|root,319AS@2|Bacteria,1Q26T@1224|Proteobacteria,42V2V@68525|delta/epsilon subdivisions,2YQFN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	putative NADH-ubiquinone oxidoreductase chain E	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADH-UOR_E
k59_831080_3	1249480.B649_01155	1.9e-54	180.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,42M9G@68525|delta/epsilon subdivisions,2YMSC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
k59_1418031_2	1265845.PWEIH_09608	1.9e-15	77.0	COG1131@1|root,COG1131@2|Bacteria,1TQHS@1239|Firmicutes,4HC34@91061|Bacilli,26N0N@186820|Listeriaceae	91061|Bacilli	V	ABC transporter, ATP-binding protein	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_1299568_1	1304883.KI912532_gene2785	1.09e-142	423.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,2VHSK@28216|Betaproteobacteria,2KV96@206389|Rhodocyclales	206389|Rhodocyclales	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
k59_1710860_1	1249480.B649_05955	2.11e-41	147.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,42M5C@68525|delta/epsilon subdivisions,2YM7M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	lytic murein transglycosylase	mltD	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
k59_1710860_2	1249480.B649_05950	3.62e-160	452.0	COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,42PQF@68525|delta/epsilon subdivisions,2YMTU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
k59_1710860_3	1249480.B649_05945	9.54e-17	75.9	COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,42NIV@68525|delta/epsilon subdivisions,2YN3P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Imidazoleglycerol-phosphate dehydratase	hisB	-	3.1.3.15,4.2.1.19	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013,R03457	RC00017,RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD,PNK3P
k59_889155_1	305700.B447_09023	3.98e-70	217.0	COG0663@1|root,COG0663@2|Bacteria,1MVUI@1224|Proteobacteria,2VH4Y@28216|Betaproteobacteria,2KUST@206389|Rhodocyclales	206389|Rhodocyclales	S	Phenylacetic acid degradation protein PaaY	-	-	-	ko:K02617	-	-	-	-	ko00000	-	-	-	Hexapep
k59_889155_2	159087.Daro_0384	3.31e-17	78.6	COG1414@1|root,COG1414@2|Bacteria,1Q7BI@1224|Proteobacteria,2VKBU@28216|Betaproteobacteria,2KYEM@206389|Rhodocyclales	206389|Rhodocyclales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
k59_66261_1	159087.Daro_4197	8.08e-42	148.0	COG0644@1|root,COG0644@2|Bacteria,1MZVI@1224|Proteobacteria,2VH6J@28216|Betaproteobacteria,2KV83@206389|Rhodocyclales	206389|Rhodocyclales	C	Tryptophan halogenase	-	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
k59_66261_2	159087.Daro_4198	4.12e-119	342.0	COG2913@1|root,COG2913@2|Bacteria,1RDAX@1224|Proteobacteria,2VTWJ@28216|Betaproteobacteria,2KYXQ@206389|Rhodocyclales	206389|Rhodocyclales	J	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1476472_1	1137799.GZ78_12720	2.4e-24	107.0	COG1835@1|root,COG1835@2|Bacteria,1RF4N@1224|Proteobacteria,1S7UV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
k59_1182701_1	1165841.SULAR_00250	2.47e-66	203.0	COG2050@1|root,COG2050@2|Bacteria,1N1PP@1224|Proteobacteria,42TRH@68525|delta/epsilon subdivisions,2YPTG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	thioesterase	-	-	-	ko:K02614	ko00360,map00360	-	R09840	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	4HBT
k59_1182701_2	1165841.SULAR_00245	1.17e-49	162.0	COG0745@1|root,COG0745@2|Bacteria,1Q4KJ@1224|Proteobacteria,42ZD8@68525|delta/epsilon subdivisions,2YRA5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
k59_1242987_1	1502770.JQMG01000001_gene1904	1.34e-148	436.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2VJFM@28216|Betaproteobacteria,2KM7U@206350|Nitrosomonadales	206350|Nitrosomonadales	L	it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction	rep	-	3.6.4.12	ko:K03656	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_300812_1	159087.Daro_0971	1.74e-65	224.0	COG2202@1|root,COG2203@1|root,COG3829@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VJGE@28216|Betaproteobacteria,2KV5M@206389|Rhodocyclales	206389|Rhodocyclales	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3
k59_1593717_1	1168067.JAGP01000001_gene653	3.37e-64	211.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,1RMXY@1236|Gammaproteobacteria,46048@72273|Thiotrichales	72273|Thiotrichales	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
k59_1536194_1	1249480.B649_02400	2.92e-114	333.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,42P56@68525|delta/epsilon subdivisions,2YNV5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
k59_891523_2	243365.CV_2319	8.21e-08	56.2	2DGQC@1|root,2ZWX5@2|Bacteria,1N40Q@1224|Proteobacteria,2VYPG@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_362167_1	317025.Tcr_2139	2.95e-60	197.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,1S5KR@1236|Gammaproteobacteria,462Q0@72273|Thiotrichales	72273|Thiotrichales	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	2.6.1.109	ko:K19715	-	-	R11395	RC00160	ko00000,ko01000,ko01005	-	-	-	DegT_DnrJ_EryC1
k59_185907_1	709032.Sulku_1960	1.06e-102	335.0	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG5000@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,COG5000@2|Bacteria,1RGKE@1224|Proteobacteria	1224|Proteobacteria	T	GAF domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,GAF,GAF_2,HATPase_c,HisKA,HisKA_2,HisKA_3,PAS,PAS_3,PAS_4,PAS_9,Pkinase,STAS,SpoIIE
k59_1832601_1	1537917.JU82_05125	4.65e-30	115.0	COG2199@1|root,COG3706@2|Bacteria,1QV14@1224|Proteobacteria,42NPJ@68525|delta/epsilon subdivisions,2YNH9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_1010482_2	709032.Sulku_1633	2.32e-19	87.0	COG2206@1|root,COG2206@2|Bacteria,1R53C@1224|Proteobacteria,42R7P@68525|delta/epsilon subdivisions,2YPRS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
k59_481963_1	709032.Sulku_0675	8.51e-20	87.4	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,42NGS@68525|delta/epsilon subdivisions,2YMZZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Ribonuclease	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB
k59_1184931_1	1161935.H9D1D6_9CAUD	5.42e-37	137.0	4QFN8@10239|Viruses,4QYWE@35237|dsDNA viruses  no RNA stage,4QS52@28883|Caudovirales,4QP1K@10744|Podoviridae	10744|Podoviridae	S	metal ion binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1538925_1	1537917.JU82_07085	9.24e-79	253.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2YMMU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_833689_1	1208919.CDSE_0127	5.57e-14	70.9	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,2VHG3@28216|Betaproteobacteria,1KPPX@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
k59_833689_2	159087.Daro_0203	7.08e-111	320.0	COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,2VIFV@28216|Betaproteobacteria,2KUW6@206389|Rhodocyclales	206389|Rhodocyclales	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
k59_833689_3	159087.Daro_0202	1.22e-40	145.0	COG1366@1|root,COG1366@2|Bacteria,1R08G@1224|Proteobacteria,2VIGK@28216|Betaproteobacteria,2KVYW@206389|Rhodocyclales	206389|Rhodocyclales	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	-	-	-	-	-	-	-	-	-	STAS_2
k59_1067900_1	1094715.CM001373_gene821	7.47e-07	50.4	COG3287@1|root,COG3287@2|Bacteria,1QUQH@1224|Proteobacteria,1RQSQ@1236|Gammaproteobacteria,1JD4A@118969|Legionellales	118969|Legionellales	S	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
k59_1067900_2	525898.Sdel_0254	4.39e-16	82.0	COG5001@1|root,COG5001@2|Bacteria,1R4H0@1224|Proteobacteria,42Q74@68525|delta/epsilon subdivisions,2YMQI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,EAL,GGDEF,PAS_3,PAS_9
k59_1713224_1	1244531.CIG1485E_1436	1.76e-12	65.9	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,42PQP@68525|delta/epsilon subdivisions,2YNQ7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	abc transporter atp-binding protein	ybbA	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_1832631_1	1165841.SULAR_10369	2.65e-204	605.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,43DMZ@68525|delta/epsilon subdivisions,2YMMS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_1832649_1	709032.Sulku_1587	3.92e-10	58.9	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,42NCJ@68525|delta/epsilon subdivisions,2YMQJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
k59_1832649_2	709032.Sulku_1588	4.92e-60	189.0	COG1472@1|root,COG1472@2|Bacteria,1QUPT@1224|Proteobacteria,42VS9@68525|delta/epsilon subdivisions,2YQD2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Cytochrome c family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365
k59_1713247_1	1249480.B649_01325	5.47e-109	319.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,42P7F@68525|delta/epsilon subdivisions,2YNFY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
k59_658668_1	1232437.KL661988_gene268	5.12e-26	113.0	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,1R91W@1224|Proteobacteria,42PXP@68525|delta/epsilon subdivisions,2WJJX@28221|Deltaproteobacteria,2MJ2Z@213118|Desulfobacterales	28221|Deltaproteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_9
k59_1832653_1	1000565.METUNv1_02798	3.82e-21	91.3	COG0491@1|root,COG0491@2|Bacteria,1MU8Q@1224|Proteobacteria,2VGZG@28216|Betaproteobacteria,2KW5P@206389|Rhodocyclales	206389|Rhodocyclales	S	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	gloB	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	HAGH_C,Lactamase_B
k59_1832653_2	1410619.SRDD_05640	5.51e-12	69.7	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,1RMFZ@1236|Gammaproteobacteria,400IW@613|Serratia	1236|Gammaproteobacteria	M	transglycosylase	mltD	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008932,GO:0008933,GO:0009893,GO:0016020,GO:0016740,GO:0016757,GO:0019222,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043085,GO:0044093,GO:0044464,GO:0048518,GO:0050789,GO:0050790,GO:0051341,GO:0051353,GO:0061783,GO:0065007,GO:0065009	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
k59_1245784_1	929558.SMGD1_0530	7.54e-107	318.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,42MRN@68525|delta/epsilon subdivisions,2YTI6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	GM	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	GDP_Man_Dehyd
k59_1245784_2	556267.HWAG_00577	8.32e-31	119.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,42M4F@68525|delta/epsilon subdivisions,2YMAG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	-	ko:K02474	ko00520,map00520	-	R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_11789_2	1537917.JU82_10780	6.36e-117	338.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,42R4H@68525|delta/epsilon subdivisions,2YNWA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0321	Guanylate_kin
k59_541503_2	1121035.AUCH01000002_gene1672	1.19e-10	61.6	COG0683@1|root,COG0683@2|Bacteria,1MWR8@1224|Proteobacteria,2VHH6@28216|Betaproteobacteria,2KVK6@206389|Rhodocyclales	206389|Rhodocyclales	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
k59_185972_1	118173.KB235914_gene3830	3.25e-30	120.0	COG1132@1|root,COG1132@2|Bacteria,1G13C@1117|Cyanobacteria,1H7SG@1150|Oscillatoriales	1117|Cyanobacteria	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k59_185972_2	666685.R2APBS1_0361	1.88e-17	83.2	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,1RMZ5@1236|Gammaproteobacteria,1X3W9@135614|Xanthomonadales	135614|Xanthomonadales	M	Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A)	lpxL	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
k59_129614_1	998088.B565_3221	9.6e-78	243.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,1RQ49@1236|Gammaproteobacteria,1Y3MR@135624|Aeromonadales	135624|Aeromonadales	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	-	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
k59_302880_1	709032.Sulku_1379	3.06e-79	247.0	COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,42PB4@68525|delta/epsilon subdivisions,2YNJ9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	ko:K15576	ko00910,ko02010,map00910,map02010	M00438	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16.1,3.A.1.16.2	-	-	NMT1_2
k59_891616_1	75379.Tint_1261	2.19e-82	259.0	COG0665@1|root,COG0665@2|Bacteria,1N1TN@1224|Proteobacteria,2VIIF@28216|Betaproteobacteria,1KJCU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	FAD dependent oxidoreductase	thiO	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
k59_891616_2	1996.JOFO01000003_gene6349	1.32e-08	53.5	COG2104@1|root,COG2104@2|Bacteria,2GQKM@201174|Actinobacteria,4EKQA@85012|Streptosporangiales	201174|Actinobacteria	H	ThiS family	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
k59_891616_3	387093.SUN_0529	2e-07	52.0	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,42MNC@68525|delta/epsilon subdivisions,2YMUY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
k59_1772007_1	90814.KL370891_gene1665	9.44e-05	45.1	COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria	1224|Proteobacteria	I	Membrane protein involved in aromatic hydrocarbon degradation	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k59_1772007_2	563040.Saut_2131	1.35e-19	87.8	COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,42NZ4@68525|delta/epsilon subdivisions,2YNNY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	COG2067 Long-chain fatty acid transport protein	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k59_1010618_1	1537917.JU82_04385	8.1e-38	136.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,42M7K@68525|delta/epsilon subdivisions,2YMZY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
k59_1010618_3	1249480.B649_04120	2.59e-31	110.0	COG2104@1|root,COG2104@2|Bacteria,1NG8E@1224|Proteobacteria,42WUA@68525|delta/epsilon subdivisions,2YQSD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	thiamine biosynthesis protein ThiS	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
k59_1421068_1	159087.Daro_0910	1.53e-78	238.0	COG3945@1|root,COG3945@2|Bacteria,1N95V@1224|Proteobacteria,2VVYB@28216|Betaproteobacteria,2KYVZ@206389|Rhodocyclales	206389|Rhodocyclales	S	Hemerythrin HHE cation binding	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
k59_1421068_2	159087.Daro_0909	3.86e-21	88.6	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2VJNG@28216|Betaproteobacteria,2KVMK@206389|Rhodocyclales	206389|Rhodocyclales	E	ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
k59_1596040_1	1123400.KB904749_gene742	2e-174	506.0	COG1982@1|root,COG1982@2|Bacteria,1MWK4@1224|Proteobacteria,1RMVF@1236|Gammaproteobacteria,460CU@72273|Thiotrichales	72273|Thiotrichales	E	Orn/Lys/Arg decarboxylase, C-terminal domain	cadA	-	4.1.1.18,4.1.1.19	ko:K01582,ko:K01584	ko00310,ko00330,ko00960,ko01100,ko01110,map00310,map00330,map00960,map01100,map01110	M00133	R00462,R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C,OKR_DC_1_N
k59_1360465_1	709032.Sulku_1845	9.12e-103	325.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,42MGK@68525|delta/epsilon subdivisions,2YMHU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_1421069_1	395963.Bind_3461	5.1e-16	79.3	COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,2TRGZ@28211|Alphaproteobacteria,3NAGP@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	Carbon-nitrogen hydrolase	-	-	3.5.5.1	ko:K01501,ko:K11206	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
k59_1421069_2	1158760.AQXP01000044_gene202	1.26e-21	102.0	COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,1RNUK@1236|Gammaproteobacteria,1WXQJ@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_2,DUF3971
k59_1832740_1	697282.Mettu_0912	3.18e-65	228.0	COG3210@1|root,COG3210@2|Bacteria,1MXIP@1224|Proteobacteria,1RSAX@1236|Gammaproteobacteria,1XG21@135618|Methylococcales	135618|Methylococcales	U	haemagglutination activity domain	-	-	-	-	-	-	-	-	-	-	-	-	Haemagg_act
k59_11851_1	748247.AZKH_3277	5.23e-70	234.0	COG1639@1|root,COG2199@1|root,COG1639@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2VHDQ@28216|Betaproteobacteria,2KW16@206389|Rhodocyclales	206389|Rhodocyclales	T	response regulator	mmoQ	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HDOD,Response_reg
k59_1479219_2	1249480.B649_09460	1.18e-78	258.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,42KZI@68525|delta/epsilon subdivisions,2YR60@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Domain of unknown function (DUF3458_C) ARM repeats	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,Peptidase_M1
k59_1360488_1	709032.Sulku_0799	0.0	1148.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YM7R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Efflux pump membrane transporter	-	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_302923_1	1502770.JQMG01000001_gene1242	1.39e-28	108.0	COG2267@1|root,COG2267@2|Bacteria,1NYNM@1224|Proteobacteria,2W9K8@28216|Betaproteobacteria,2KNIE@206350|Nitrosomonadales	206350|Nitrosomonadales	I	Thioesterase domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
k59_302923_2	583345.Mmol_0426	1.12e-122	354.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,2VSKZ@28216|Betaproteobacteria,2KNEA@206350|Nitrosomonadales	206350|Nitrosomonadales	O	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase	-	-	5.2.1.8	ko:K03773	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
k59_362337_1	1249480.B649_00360	2.03e-13	67.0	COG3545@1|root,COG3545@2|Bacteria,1MZB5@1224|Proteobacteria,43B8G@68525|delta/epsilon subdivisions,2YT6R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Serine hydrolase	-	-	-	ko:K07002	-	-	-	-	ko00000	-	-	-	Ser_hydrolase
k59_362337_2	709032.Sulku_0042	1.69e-83	254.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,42MHX@68525|delta/epsilon subdivisions,2YMXF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
k59_1245915_1	435908.IDSA_04305	3.05e-05	47.0	COG2199@1|root,COG4251@1|root,COG3706@2|Bacteria,COG4251@2|Bacteria,1R7HC@1224|Proteobacteria,1T2WX@1236|Gammaproteobacteria,2QGSS@267893|Idiomarinaceae	1236|Gammaproteobacteria	T	Phytochrome region	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GGDEF,PAS_2,PHY
k59_1245915_3	395961.Cyan7425_0164	4.67e-15	73.6	COG2110@1|root,COG2110@2|Bacteria,1G5VN@1117|Cyanobacteria,3KHWD@43988|Cyanothece	1117|Cyanobacteria	S	Appr-1-p processing domain	-	-	-	-	-	-	-	-	-	-	-	-	Macro
k59_1185074_1	1537915.JU57_05175	2.62e-21	100.0	COG1404@1|root,COG2304@1|root,COG2931@1|root,COG3210@1|root,COG5625@1|root,COG1404@2|Bacteria,COG2304@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG5625@2|Bacteria,1MU7T@1224|Proteobacteria,42PPF@68525|delta/epsilon subdivisions,2YRRN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1596090_1	273121.WS1395	2.21e-27	102.0	2A433@1|root,30SN2@2|Bacteria,1PBWY@1224|Proteobacteria,42VT4@68525|delta/epsilon subdivisions,2YQB2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1010714_2	1249480.B649_02150	6.42e-35	122.0	COG1539@1|root,COG1539@2|Bacteria,1RHII@1224|Proteobacteria,42V1R@68525|delta/epsilon subdivisions,2YQ8Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	dihydroneopterin aldolase	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
k59_1010714_3	709032.Sulku_0438	3.22e-69	213.0	COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,42QQP@68525|delta/epsilon subdivisions,2YNZZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
k59_1185097_1	1121035.AUCH01000014_gene2483	4.18e-06	50.4	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,2KV7D@206389|Rhodocyclales	206389|Rhodocyclales	NT	Cache_2	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,dCache_2,sCache_2
k59_833907_1	159087.Daro_0711	3.92e-183	532.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,1MU08@1224|Proteobacteria,2VJSM@28216|Betaproteobacteria,2KV1V@206389|Rhodocyclales	206389|Rhodocyclales	P	cation transport ATPase	ccoI	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
k59_1301715_1	1158292.JPOE01000005_gene68	2.52e-08	60.1	COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VJSZ@28216|Betaproteobacteria,1KJ24@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Signal transducing histidine kinase, homodimeric domain	pilL	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k59_265872_1	387093.SUN_1534	8.65e-205	579.0	COG1696@1|root,COG1696@2|Bacteria,1MUXN@1224|Proteobacteria,42MIR@68525|delta/epsilon subdivisions,2YN3N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Alginate O-acetylation protein	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
k59_265873_1	709032.Sulku_0873	7.77e-159	451.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,42M84@68525|delta/epsilon subdivisions,2YN32@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
k59_1385309_2	387093.SUN_0175	1.57e-105	307.0	COG2952@1|root,COG2952@2|Bacteria,1PBRU@1224|Proteobacteria,42MEP@68525|delta/epsilon subdivisions,2YN8A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09804	-	-	-	-	ko00000	-	-	-	DUF507
k59_1385309_3	387093.SUN_0174	3.68e-149	429.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,42M9E@68525|delta/epsilon subdivisions,2YMCM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
k59_1155449_1	709032.Sulku_1273	2.26e-34	130.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,42N30@68525|delta/epsilon subdivisions,2YMCR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the pyruvate kinase family	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK
k59_730602_1	1537917.JU82_04005	8.36e-266	730.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,42MUZ@68525|delta/epsilon subdivisions,2YMR3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_730602_2	709032.Sulku_0366	2.33e-23	95.9	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,42NC2@68525|delta/epsilon subdivisions,2YMTQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
k59_571234_1	709032.Sulku_2474	8.16e-52	173.0	29Y2F@1|root,30JVD@2|Bacteria,1RAWX@1224|Proteobacteria,4300B@68525|delta/epsilon subdivisions,2YRWY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_571234_2	709032.Sulku_2475	1.01e-37	130.0	COG0226@1|root,COG0226@2|Bacteria,1N3EC@1224|Proteobacteria,42XZP@68525|delta/epsilon subdivisions,2YSV9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_625167_1	1121035.AUCH01000008_gene999	1.51e-84	264.0	COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,2VH82@28216|Betaproteobacteria,2KUF7@206389|Rhodocyclales	206389|Rhodocyclales	P	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
k59_571240_1	159087.Daro_2621	2.86e-24	95.9	2E2ZN@1|root,32Y09@2|Bacteria,1NCRB@1224|Proteobacteria,2VWPA@28216|Betaproteobacteria,2KZ8P@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1568001_1	1249480.B649_03465	3.98e-68	226.0	COG1256@1|root,COG1749@1|root,COG1256@2|Bacteria,COG1749@2|Bacteria,1MV2M@1224|Proteobacteria,42PBN@68525|delta/epsilon subdivisions,2YMGR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar hook-associated protein	flgK	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k59_730639_1	1101195.Meth11DRAFT_2329	5.44e-95	278.0	COG2010@1|root,COG2010@2|Bacteria,1QBNV@1224|Proteobacteria,2W7YT@28216|Betaproteobacteria,2KMPU@206350|Nitrosomonadales	206350|Nitrosomonadales	C	PFAM Cytochrome C	-	-	-	ko:K16255	ko00680,ko01120,map00680,map01120	-	-	-	ko00000,ko00001	-	-	-	Cytochrome_CBB3
k59_30692_1	1227453.C444_20916	3.42e-22	100.0	COG0444@1|root,COG4608@1|root,arCOG00181@2157|Archaea,arCOG00184@2157|Archaea,2XSTM@28890|Euryarchaeota,240TG@183963|Halobacteria	183963|Halobacteria	E	COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
k59_914424_2	1537917.JU82_07725	1e-46	151.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,42TPZ@68525|delta/epsilon subdivisions,2YPU9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
k59_211882_1	1500890.JQNL01000001_gene3710	2.52e-36	135.0	COG3001@1|root,COG3001@2|Bacteria,1MVHX@1224|Proteobacteria,1RRC5@1236|Gammaproteobacteria,1X8QK@135614|Xanthomonadales	135614|Xanthomonadales	G	Fructosamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
k59_1275116_2	709032.Sulku_0761	2.47e-70	216.0	COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,42PKF@68525|delta/epsilon subdivisions,2YNC3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	MotA TolQ ExbB proton channel family	tolQ	-	-	-	-	-	-	-	-	-	-	-	MotA_ExbB
k59_1208251_1	159087.Daro_3011	1.19e-09	55.8	COG0346@1|root,COG0346@2|Bacteria,1N116@1224|Proteobacteria,2VRA3@28216|Betaproteobacteria,2KWTU@206389|Rhodocyclales	206389|Rhodocyclales	E	Glyoxalase-like domain	-	-	-	ko:K07032	-	-	-	-	ko00000	-	-	-	Glyoxalase
k59_1208251_2	426114.THI_0213	4.61e-14	65.9	2DR1A@1|root,339RT@2|Bacteria,1NGFB@1224|Proteobacteria,2VXU8@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3096)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3096
k59_1501221_1	90814.KL370891_gene1601	6.94e-49	169.0	COG1577@1|root,COG1577@2|Bacteria,1NF04@1224|Proteobacteria	1224|Proteobacteria	I	mevalonate kinase	-	-	2.7.1.36	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	M00095	R02245	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
k59_1678100_1	563040.Saut_1457	3e-08	57.0	COG0457@1|root,COG0457@2|Bacteria,1N9AG@1224|Proteobacteria,42QUG@68525|delta/epsilon subdivisions,2YP2D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF3137)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3137
k59_730696_1	709032.Sulku_1951	4.5e-88	270.0	COG0642@1|root,COG2205@2|Bacteria,1RK1D@1224|Proteobacteria,42R91@68525|delta/epsilon subdivisions,2YNX3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
k59_730696_2	1537917.JU82_00190	6.64e-55	179.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,42P1N@68525|delta/epsilon subdivisions,2YTRU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
k59_211922_1	1249480.B649_08015	1.1e-92	277.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,42MV7@68525|delta/epsilon subdivisions,2YMFH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
k59_1736697_2	709032.Sulku_0019	1.13e-65	217.0	COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,42RCJ@68525|delta/epsilon subdivisions,2YNX9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG4775 Outer membrane protein protective antigen OMA87	-	-	-	ko:K07278	-	-	-	-	ko00000,ko02000	1.B.33.2.4	-	-	Bac_surface_Ag,POTRA
k59_88902_1	1280950.HJO_07217	7.86e-53	181.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,2TRKK@28211|Alphaproteobacteria,43W4U@69657|Hyphomonadaceae	28211|Alphaproteobacteria	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
k59_1042680_1	1502770.JQMG01000001_gene826	1.65e-26	100.0	2927S@1|root,2ZPSE@2|Bacteria,1NPN8@1224|Proteobacteria,2VZ0K@28216|Betaproteobacteria,2KNBJ@206350|Nitrosomonadales	206350|Nitrosomonadales	S	ATP synthase I chain	-	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATP-synt_I
k59_1042680_2	583345.Mmol_2337	3.68e-66	207.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,2VHR5@28216|Betaproteobacteria,2KKB3@206350|Nitrosomonadales	206350|Nitrosomonadales	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
k59_1678162_2	1249480.B649_05860	5.81e-30	107.0	2AK4P@1|root,31AUI@2|Bacteria,1Q664@1224|Proteobacteria,42X10@68525|delta/epsilon subdivisions,2YQR8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_914526_1	1502770.JQMG01000001_gene2121	5.13e-88	261.0	COG1451@1|root,COG1451@2|Bacteria,1RDJ9@1224|Proteobacteria,2VR4I@28216|Betaproteobacteria,2KMWV@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
k59_800863_1	159087.Daro_0993	5.25e-41	147.0	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,2VKMW@28216|Betaproteobacteria,2KV2G@206389|Rhodocyclales	206389|Rhodocyclales	I	Poly-beta-hydroxybutyrate	-	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	PhaC_N
k59_800863_2	159087.Daro_0994	6.53e-49	162.0	COG0840@1|root,COG0840@2|Bacteria,1RECT@1224|Proteobacteria,2VRNK@28216|Betaproteobacteria,2KWC6@206389|Rhodocyclales	206389|Rhodocyclales	NT	transmembrane signaling receptor activity	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal
k59_1678169_1	717773.Thicy_0558	2.57e-24	105.0	COG4268@1|root,COG4268@2|Bacteria,1N9D3@1224|Proteobacteria,1SCPU@1236|Gammaproteobacteria,463FC@72273|Thiotrichales	72273|Thiotrichales	V	McrBC 5-methylcytosine restriction system component	-	-	-	-	-	-	-	-	-	-	-	-	McrBC
k59_211967_1	1537917.JU82_10555	9.59e-75	243.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,42MP3@68525|delta/epsilon subdivisions,2YMP3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
k59_156463_1	709032.Sulku_2512	5.74e-125	370.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,42MEM@68525|delta/epsilon subdivisions,2YMWQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
k59_211980_1	367737.Abu_1121	9.71e-30	118.0	COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,42MCZ@68525|delta/epsilon subdivisions,2YNV4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	HlyD membrane-fusion protein of T1SS	-	-	-	ko:K12542	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	3.A.1.109.4,8.A.1	-	-	HlyD_3
k59_211980_2	929558.SMGD1_2209	3.99e-09	57.4	COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,42MP9@68525|delta/epsilon subdivisions,2YMN8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Type I secretion system ATPase	-	-	-	ko:K12541	ko02010,map02010	M00330	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.109.3,3.A.1.109.4	-	-	ABC_membrane,ABC_tran
k59_268764_1	653733.Selin_1142	0.000814	42.0	COG2202@1|root,COG2203@1|root,COG5000@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG5000@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.1.1.80,2.7.13.3,2.7.8.41,3.1.1.61	ko:K07716,ko:K08744,ko:K13598,ko:K13924	ko00564,ko01100,ko02020,ko02030,ko04112,map00564,map01100,map02020,map02030,map04112	M00498,M00506,M00511	R02030	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg,SpoIIE
k59_268764_2	1249480.B649_08220	8.13e-45	154.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,42PDR@68525|delta/epsilon subdivisions,2YN5V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	a g-specific adenine glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
k59_1619633_1	265072.Mfla_2583	9.04e-63	212.0	COG1289@1|root,COG1289@2|Bacteria,1MX9H@1224|Proteobacteria,2VK3A@28216|Betaproteobacteria,2KMIG@206350|Nitrosomonadales	206350|Nitrosomonadales	S	PFAM Fusaric acid resistance protein conserved region	-	-	-	-	-	-	-	-	-	-	-	-	FUSC
k59_508411_1	292563.Cyast_0733	7.05e-29	107.0	COG1569@1|root,COG1569@2|Bacteria,1G7HY@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM PilT protein domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
k59_508411_2	1249480.B649_10895	4.44e-54	175.0	COG0602@1|root,COG0602@2|Bacteria,1PDNI@1224|Proteobacteria,42R24@68525|delta/epsilon subdivisions,2YN2N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_12,Fer4_14
k59_444730_1	709032.Sulku_0387	1.22e-91	279.0	29W5U@1|root,30HQY@2|Bacteria,1QUJN@1224|Proteobacteria,42NUV@68525|delta/epsilon subdivisions,2YNFP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1794777_1	717773.Thicy_1482	2.93e-88	283.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,4603G@72273|Thiotrichales	72273|Thiotrichales	L	it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction	rep	-	3.6.4.12	ko:K03656	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_156500_1	709032.Sulku_1511	8.59e-107	335.0	COG2199@1|root,COG2200@1|root,COG3287@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,COG3287@2|Bacteria,1NQKX@1224|Proteobacteria,43DAG@68525|delta/epsilon subdivisions,2YTHK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,FIST,FIST_C,GGDEF,PAS_9
k59_1568178_1	1249480.B649_00905	8.41e-155	452.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,42SPZ@68525|delta/epsilon subdivisions,2YMS1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	fdhF	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_88977_1	1537917.JU82_10995	1.38e-22	94.4	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,42N9Q@68525|delta/epsilon subdivisions,2YMUH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	iIT341.HP0921	Gp_dh_C,Gp_dh_N
k59_88977_2	1537917.JU82_10990	2.72e-74	226.0	COG1057@1|root,COG1057@2|Bacteria,1NG4J@1224|Proteobacteria,42P0F@68525|delta/epsilon subdivisions,2YQ32@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP1337	CTP_transf_like
k59_1093142_2	709032.Sulku_1882	5.26e-121	351.0	COG1090@1|root,COG1090@2|Bacteria,1MUB4@1224|Proteobacteria,42QUU@68525|delta/epsilon subdivisions,2YNXM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Epimerase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
k59_1042790_1	506534.Rhein_0943	1.6e-24	108.0	28HUW@1|root,2Z81F@2|Bacteria,1Q3QA@1224|Proteobacteria,1RPFU@1236|Gammaproteobacteria,1WWUK@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_571391_1	709032.Sulku_0566	1.69e-58	206.0	COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2YMB9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	chemotaxis protein	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k59_1385587_2	1111728.ATYS01000015_gene4732	2.16e-28	109.0	COG4319@1|root,COG4319@2|Bacteria,1RBU6@1224|Proteobacteria,1S33C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	ketosteroid isomerase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
k59_1275346_1	1123518.ARWI01000001_gene568	1.69e-32	116.0	COG0350@1|root,COG0350@2|Bacteria	2|Bacteria	L	methylated-DNA-[protein]-cysteine S-methyltransferase activity	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
k59_1275346_2	317025.Tcr_1958	7.12e-23	97.4	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,1RMY7@1236|Gammaproteobacteria,45ZPY@72273|Thiotrichales	72273|Thiotrichales	E	Glutamate synthase	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
k59_508503_2	1249480.B649_08160	2.96e-230	640.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,42MAH@68525|delta/epsilon subdivisions,2YMZK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
k59_730894_1	709032.Sulku_0999	3.17e-111	325.0	COG1058@1|root,COG1058@2|Bacteria,1MVG6@1224|Proteobacteria,42R50@68525|delta/epsilon subdivisions,2YNX5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
k59_1568224_1	709032.Sulku_0363	4.96e-112	326.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,42MB9@68525|delta/epsilon subdivisions,2YMN0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	IQ	reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_914674_1	1165841.SULAR_03592	4.73e-90	289.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2YRKW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0474 Cation transport ATPase	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
k59_444829_1	572480.Arnit_1741	2.02e-11	69.7	COG3515@1|root,COG3515@2|Bacteria,1RC37@1224|Proteobacteria,43ACE@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ	-	-	-	ko:K11910	-	M00334	-	-	ko00000,ko00002,ko02044	3.A.23.1	-	-	ImpA_N,T6SS_VasJ
k59_30923_1	1537917.JU82_00095	7.76e-127	369.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,42MNJ@68525|delta/epsilon subdivisions,2YMDC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
k59_1155808_1	709032.Sulku_0308	1.71e-42	148.0	COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria,42P5V@68525|delta/epsilon subdivisions,2YNBJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	msrP	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
k59_1568242_1	1249480.B649_08270	2.21e-64	204.0	COG0810@1|root,COG0810@2|Bacteria,1QAAM@1224|Proteobacteria,42X9R@68525|delta/epsilon subdivisions,2YQQ7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	TonB C terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_2
k59_1501483_1	580332.Slit_0154	3.95e-101	308.0	COG3707@1|root,COG3707@2|Bacteria,1MXDV@1224|Proteobacteria,2W9S9@28216|Betaproteobacteria,44WN9@713636|Nitrosomonadales	28216|Betaproteobacteria	T	ANTAR	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR
k59_1501483_2	1454004.AW11_02642	6.67e-25	99.0	2AR1G@1|root,31GAD@2|Bacteria,1MYR6@1224|Proteobacteria,2VTGU@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TerB
k59_30944_1	387093.SUN_2047	4.9e-19	83.6	COG1692@1|root,COG1692@2|Bacteria,1MW12@1224|Proteobacteria,42PCG@68525|delta/epsilon subdivisions,2YN6X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	metallophosphoesterase	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
k59_30944_2	1165841.SULAR_06903	3.41e-64	214.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,42M09@68525|delta/epsilon subdivisions,2YMWR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
k59_508561_2	159087.Daro_0057	6.39e-09	54.7	COG0560@1|root,COG0560@2|Bacteria,1MZPG@1224|Proteobacteria,2VHDT@28216|Betaproteobacteria,2KVYK@206389|Rhodocyclales	206389|Rhodocyclales	E	phosphoserine phosphatase	thrH	-	2.7.1.39,3.1.3.3	ko:K02203	ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00680,map01100,map01110,map01120,map01130,map01230	M00018	R00582,R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD,Hydrolase
k59_978733_1	946483.Cenrod_2629	1.23e-27	110.0	COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,2VH5M@28216|Betaproteobacteria,4AB5K@80864|Comamonadaceae	28216|Betaproteobacteria	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
k59_978733_2	90813.JQMT01000001_gene539	2.94e-58	190.0	COG2890@1|root,COG2890@2|Bacteria,1MX8Q@1224|Proteobacteria,1RPHQ@1236|Gammaproteobacteria,45ZV3@72273|Thiotrichales	72273|Thiotrichales	J	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue	prmB	-	2.1.1.298	ko:K07320	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03009	-	-	-	MTS
k59_1736929_1	1122139.KB907862_gene647	4.2e-99	309.0	COG0380@1|root,COG0561@1|root,COG0380@2|Bacteria,COG0561@2|Bacteria,1MUIY@1224|Proteobacteria,1RNG7@1236|Gammaproteobacteria,1XN6H@135619|Oceanospirillales	135619|Oceanospirillales	G	Glycosyltransferase family 20	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_20,S6PP
k59_444884_1	159087.Daro_0027	4.37e-76	238.0	28JIP@1|root,2Z82C@2|Bacteria,1R5N9@1224|Proteobacteria,2VRZW@28216|Betaproteobacteria,2KWSG@206389|Rhodocyclales	206389|Rhodocyclales	S	S1/P1 Nuclease	-	-	-	-	-	-	-	-	-	-	-	-	S1-P1_nuclease
k59_444884_2	1123393.KB891331_gene2950	4.82e-12	66.2	COG2199@1|root,COG3706@2|Bacteria,1N9PI@1224|Proteobacteria,2VJV4@28216|Betaproteobacteria,1KSIX@119069|Hydrogenophilales	119069|Hydrogenophilales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_1861861_1	1249480.B649_07465	8.16e-126	370.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,42M04@68525|delta/epsilon subdivisions,2YMAR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
k59_321816_1	387093.SUN_0031	1.69e-95	293.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2YMIX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE
k59_321816_2	387093.SUN_0032	2.23e-31	116.0	2BSET@1|root,32MGT@2|Bacteria,1Q39R@1224|Proteobacteria,42WZN@68525|delta/epsilon subdivisions,2YQU4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
k59_1095779_1	631362.Thi970DRAFT_00795	2.31e-64	205.0	arCOG03638@1|root,2Z7NN@2|Bacteria,1R3Y6@1224|Proteobacteria,1RTWY@1236|Gammaproteobacteria,1X2HW@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF1538)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1538
k59_1278571_1	1537917.JU82_11240	2.25e-62	199.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,42M1B@68525|delta/epsilon subdivisions,2YMCC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
k59_1278571_2	1150621.SMUL_1906	3.38e-08	55.1	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,42MUG@68525|delta/epsilon subdivisions,2YMMM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
k59_159243_2	944547.ABLL_0822	1.61e-11	66.2	COG0463@1|root,COG0463@2|Bacteria,1N8QE@1224|Proteobacteria,43BJ3@68525|delta/epsilon subdivisions,2YT90@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_804269_1	1168067.JAGP01000001_gene1282	1.02e-37	129.0	COG0454@1|root,COG0456@2|Bacteria,1N7JM@1224|Proteobacteria,1SDWW@1236|Gammaproteobacteria,462MF@72273|Thiotrichales	72273|Thiotrichales	K	Protein of unknown function (DUF3579)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3579
k59_804269_2	59196.RICGR_0388	5.22e-47	166.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,1RNHU@1236|Gammaproteobacteria,1JCN2@118969|Legionellales	118969|Legionellales	F	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
k59_691724_1	439235.Dalk_3065	1.65e-14	73.2	2E6WH@1|root,331G1@2|Bacteria,1NCI3@1224|Proteobacteria,42V38@68525|delta/epsilon subdivisions,2WRZD@28221|Deltaproteobacteria,2MKW9@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1571515_2	1537917.JU82_09320	2.76e-27	110.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2YMRQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_918356_2	709032.Sulku_1180	3.3e-140	402.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,42N9Q@68525|delta/epsilon subdivisions,2YMUH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	iIT341.HP1346	Gp_dh_C,Gp_dh_N
k59_1326320_1	797209.ZOD2009_04012	0.00015	47.0	COG0656@1|root,arCOG01619@2157|Archaea,2XTJ4@28890|Euryarchaeota,23SMW@183963|Halobacteria	183963|Halobacteria	S	COG0656 Aldo keto reductases, related to diketogulonate reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_353948_1	709032.Sulku_2185	5.92e-143	409.0	COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,42M3V@68525|delta/epsilon subdivisions,2YMJP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0625	GcpE
k59_1351966_1	1123269.NX02_22870	4.02e-12	71.6	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,2K2CT@204457|Sphingomonadales	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
k59_1000070_1	85643.Tmz1t_3596	6.51e-33	123.0	COG1637@1|root,COG3586@1|root,COG1637@2|Bacteria,COG3586@2|Bacteria,1R4TU@1224|Proteobacteria,2VMI3@28216|Betaproteobacteria,2KYDW@206389|Rhodocyclales	206389|Rhodocyclales	L	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1000070_2	395494.Galf_1563	1.79e-62	208.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,2VH8W@28216|Betaproteobacteria,44VG6@713636|Nitrosomonadales	28216|Betaproteobacteria	L	DEAD DEAH box helicase domain protein	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
k59_706239_1	159087.Daro_1787	3.8e-71	227.0	COG1639@1|root,COG1639@2|Bacteria,1RFEZ@1224|Proteobacteria,2VRI2@28216|Betaproteobacteria,2KX6S@206389|Rhodocyclales	206389|Rhodocyclales	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_1234878_1	90813.JQMT01000001_gene1002	4.22e-80	246.0	COG3435@1|root,COG3435@2|Bacteria,1RBES@1224|Proteobacteria,1S33X@1236|Gammaproteobacteria,460P2@72273|Thiotrichales	72273|Thiotrichales	Q	Gentisate 1,2-dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1058452_1	317025.Tcr_1548	3.4e-73	243.0	COG0466@1|root,COG0466@2|Bacteria,1NTR5@1224|Proteobacteria,1RPID@1236|Gammaproteobacteria,461XY@72273|Thiotrichales	72273|Thiotrichales	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_648339_1	1537917.JU82_01245	7.16e-45	152.0	COG3076@1|root,COG3076@2|Bacteria,1N195@1224|Proteobacteria,430TX@68525|delta/epsilon subdivisions,2YS1B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Family of unknown function (DUF695)	-	-	-	-	-	-	-	-	-	-	-	-	DUF695,RraB
k59_648339_2	1537917.JU82_01250	5.99e-27	110.0	2AJGC@1|root,31A2T@2|Bacteria,1Q4TA@1224|Proteobacteria,42ZUH@68525|delta/epsilon subdivisions,2YRV9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1763224_1	317025.Tcr_0008	7.28e-73	245.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,4602H@72273|Thiotrichales	72273|Thiotrichales	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
k59_119524_1	1502770.JQMG01000001_gene1469	1.92e-43	146.0	COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,2VSEQ@28216|Betaproteobacteria,2KMM6@206350|Nitrosomonadales	206350|Nitrosomonadales	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
k59_2813_1	1165841.SULAR_05508	1.62e-128	383.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MHP@68525|delta/epsilon subdivisions,2YN92@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k59_941474_1	76114.ebA1712	1.42e-70	231.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,2VHS3@28216|Betaproteobacteria,2KV81@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
k59_1645709_1	1158150.KB906242_gene220	2.54e-81	260.0	28MSK@1|root,2ZB0X@2|Bacteria,1R7CY@1224|Proteobacteria	1224|Proteobacteria	S	Bacteriophage head to tail connecting protein	-	-	-	-	-	-	-	-	-	-	-	-	Head-tail_con
k59_1822391_1	944547.ABLL_1024	8.15e-37	127.0	COG1051@1|root,COG1051@2|Bacteria,1QUM0@1224|Proteobacteria,42SY6@68525|delta/epsilon subdivisions,2YPEG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	ADP-ribose pyrophosphatase	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
k59_648369_2	709032.Sulku_0076	1.38e-254	701.0	COG0027@1|root,COG0027@2|Bacteria,1N3KA@1224|Proteobacteria,42MYW@68525|delta/epsilon subdivisions,2YN5Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate	purT	-	2.1.2.2	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
k59_648369_3	1249480.B649_00170	6.56e-69	216.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,42M8N@68525|delta/epsilon subdivisions,2YMFN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	hprA	-	1.1.1.29	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	M00346	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
k59_941484_1	1144319.PMI16_04926	4.4e-62	198.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,2VRBV@28216|Betaproteobacteria,478XB@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	ko:K14979	ko02020,map02020	M00663	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
k59_1117288_1	62928.azo0341	7.38e-48	158.0	COG3909@1|root,COG3909@2|Bacteria,1MYH4@1224|Proteobacteria,2VSDJ@28216|Betaproteobacteria,2KWUM@206389|Rhodocyclales	206389|Rhodocyclales	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_2
k59_1117288_2	159087.Daro_1889	2.75e-08	52.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,2VSHQ@28216|Betaproteobacteria,2KWDK@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
k59_1645723_1	644282.Deba_0734	2.2e-30	118.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,42M15@68525|delta/epsilon subdivisions,2WIQN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
k59_1822408_1	709032.Sulku_0982	2.52e-07	50.8	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2YMMT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_1822408_2	1249480.B649_05655	1.4e-108	318.0	COG4786@1|root,COG4786@2|Bacteria,1PZ24@1224|Proteobacteria,42NGI@68525|delta/epsilon subdivisions,2YNFE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar basal body	flgG2	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k59_530929_1	261292.Nit79A3_2654	1.24e-52	167.0	COG2963@1|root,COG2963@2|Bacteria,1N1AA@1224|Proteobacteria,2VSJA@28216|Betaproteobacteria,373QX@32003|Nitrosomonadales	28216|Betaproteobacteria	L	PFAM Transposase IS3 IS911	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
k59_530929_2	380358.XALC_2631	5.27e-177	498.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1RSHU@1236|Gammaproteobacteria,1X9I1@135614|Xanthomonadales	135614|Xanthomonadales	L	transposases go 0004803	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve
k59_941516_1	1172190.M947_09990	7.27e-33	125.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,42MJE@68525|delta/epsilon subdivisions,2YN7F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	actP	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
k59_119571_1	1249480.B649_01510	3.14e-70	214.0	COG1714@1|root,COG1714@2|Bacteria,1N7R6@1224|Proteobacteria,42U2T@68525|delta/epsilon subdivisions,2YPV6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
k59_119571_2	709032.Sulku_0333	5.75e-142	409.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,42MCI@68525|delta/epsilon subdivisions,2YMR4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
k59_1587371_1	709032.Sulku_1756	7.44e-81	262.0	COG2307@1|root,COG2308@1|root,COG2307@2|Bacteria,COG2308@2|Bacteria,1MX5P@1224|Proteobacteria,42NB9@68525|delta/epsilon subdivisions,2YNN4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E,CP_ATPgrasp_2
k59_2876_1	1249480.B649_07475	1.51e-32	121.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,42M46@68525|delta/epsilon subdivisions,2YMYR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
k59_2876_2	709032.Sulku_0935	1.42e-51	172.0	COG0859@1|root,COG0859@2|Bacteria,1N2DA@1224|Proteobacteria,439YU@68525|delta/epsilon subdivisions,2YRNJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COGs COG0859 ADP-heptose LPS heptosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
k59_941523_1	709032.Sulku_0993	3.15e-74	238.0	COG0791@1|root,COG0791@2|Bacteria,1R45H@1224|Proteobacteria,42NS0@68525|delta/epsilon subdivisions,2YN06@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,N_NLPC_P60,Peptidase_M15_4,SH3_6,SH3_7
k59_413036_1	709032.Sulku_1054	4.54e-85	259.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,42N1R@68525|delta/epsilon subdivisions,2YMRZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_764919_1	1537917.JU82_08410	4.86e-42	146.0	COG2899@1|root,COG2899@2|Bacteria,1NURT@1224|Proteobacteria,42MRA@68525|delta/epsilon subdivisions,2YNAM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF475)	-	-	-	ko:K09799	-	-	-	-	ko00000	-	-	-	DUF475
k59_472000_1	929558.SMGD1_0017	4.71e-95	291.0	COG1362@1|root,COG1362@2|Bacteria,1NT1D@1224|Proteobacteria,42MN0@68525|delta/epsilon subdivisions,2YRFV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	M18 family aminopeptidase	-	-	3.4.11.21	ko:K01267	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	Peptidase_M18
k59_472000_2	748247.AZKH_3091	2.39e-41	149.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2VH0Q@28216|Betaproteobacteria,2KUIB@206389|Rhodocyclales	206389|Rhodocyclales	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1176487_1	1249480.B649_00595	8.88e-82	265.0	COG0715@1|root,COG0834@1|root,COG4191@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PNA@68525|delta/epsilon subdivisions,2YTBI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EPT	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,NMT1,SBP_bac_3
k59_295444_1	709032.Sulku_0063	5.76e-40	135.0	COG1547@1|root,COG1547@2|Bacteria,1PD94@1224|Proteobacteria,42WUE@68525|delta/epsilon subdivisions,2YQXY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function (DUF309)	-	-	-	-	-	-	-	-	-	-	-	-	DUF309
k59_295444_2	1249480.B649_00215	3.41e-59	183.0	COG0607@1|root,COG0607@2|Bacteria,1Q1NN@1224|Proteobacteria,42U2F@68525|delta/epsilon subdivisions,2YQ1E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_295444_3	709032.Sulku_0065	3.64e-66	223.0	COG4581@1|root,COG4581@2|Bacteria,1MVD6@1224|Proteobacteria,42PR3@68525|delta/epsilon subdivisions,2YN2Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Mitochondrial degradasome RNA helicase subunit C terminal	-	-	3.6.4.13	ko:K17675	-	-	-	-	ko00000,ko01000,ko03029	-	-	-	Helicase_C,SUV3_C
k59_1528900_1	335543.Sfum_2963	4.16e-30	125.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,42MD4@68525|delta/epsilon subdivisions,2WJ7Z@28221|Deltaproteobacteria,2MR89@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	Helicase associated domain (HA2)  Add an annotation	hrpA	-	3.6.4.13	ko:K03578,ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	AAA_19,DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
k59_237043_1	1249480.B649_03785	2.96e-135	385.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,42PTX@68525|delta/epsilon subdivisions,2YMNS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
k59_941571_1	1165841.SULAR_08392	9.95e-136	392.0	COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,42NI7@68525|delta/epsilon subdivisions,2YMH9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_941571_2	749222.Nitsa_0056	2.79e-07	51.6	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,42M9X@68525|delta/epsilon subdivisions,2YMQ1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
k59_1528909_1	387093.SUN_1098	4.74e-09	55.8	2BEW6@1|root,328MU@2|Bacteria,1QAUA@1224|Proteobacteria,42VY6@68525|delta/epsilon subdivisions,2YQED@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1528909_2	1537917.JU82_05585	9.71e-104	307.0	COG2005@1|root,COG3585@1|root,COG2005@2|Bacteria,COG3585@2|Bacteria,1P9SX@1224|Proteobacteria,42RG9@68525|delta/epsilon subdivisions,2YMVF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Transcriptional regulator, ModE family	modE	-	-	ko:K02019	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,TOBE
k59_824174_1	159087.Daro_1118	2.86e-140	414.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,2KVJ3@206389|Rhodocyclales	206389|Rhodocyclales	JKL	DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation	deaD	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
k59_882686_2	159087.Daro_1300	6.61e-64	207.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,2VHJJ@28216|Betaproteobacteria,2KV4N@206389|Rhodocyclales	206389|Rhodocyclales	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
k59_237057_1	84531.JMTZ01000051_gene922	1.05e-56	195.0	COG4805@1|root,COG4805@2|Bacteria,1R5EP@1224|Proteobacteria,1RRS6@1236|Gammaproteobacteria,1X3WH@135614|Xanthomonadales	135614|Xanthomonadales	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
k59_1235037_1	1249480.B649_07280	9.32e-30	117.0	COG2199@1|root,COG3706@2|Bacteria,1Q5A3@1224|Proteobacteria,430W0@68525|delta/epsilon subdivisions,2YRZB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_1235037_2	1249480.B649_07275	1.51e-61	197.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,42MYJ@68525|delta/epsilon subdivisions,2YN0I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS
k59_589227_1	159087.Daro_1052	1.56e-192	548.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KYB0@206389|Rhodocyclales	206389|Rhodocyclales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_589227_2	159087.Daro_1053	4.11e-16	71.2	COG2608@1|root,COG2608@2|Bacteria,1NGBD@1224|Proteobacteria,2VXV9@28216|Betaproteobacteria,2KXPB@206389|Rhodocyclales	206389|Rhodocyclales	P	Heavy-metal-associated domain	-	-	-	ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
k59_119656_1	1121380.JNIW01000014_gene2412	8.56e-87	271.0	COG1249@1|root,COG1249@2|Bacteria	2|Bacteria	C	cell redox homeostasis	sthA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.6.1.1	ko:K00322	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
k59_531036_1	438753.AZC_3580	1.17e-11	77.4	COG3170@1|root,COG3170@2|Bacteria,1Q45C@1224|Proteobacteria,2U08F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1352134_1	1537917.JU82_09590	1.4e-108	322.0	COG1373@1|root,COG1373@2|Bacteria,1QP8R@1224|Proteobacteria,42SQ9@68525|delta/epsilon subdivisions,2YPG4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	ATPase (AAA	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14
k59_2988_1	1249480.B649_11465	3.51e-62	191.0	COG0640@1|root,COG0640@2|Bacteria,1MZPS@1224|Proteobacteria,4322C@68525|delta/epsilon subdivisions	1224|Proteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
k59_2988_2	1249480.B649_11485	5.57e-24	95.1	2C5EJ@1|root,33CUW@2|Bacteria,1PVYS@1224|Proteobacteria,4327Q@68525|delta/epsilon subdivisions,2YSV7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function VcgC/VcgE (DUF2780)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2780
k59_1469424_1	709032.Sulku_2544	5.76e-141	403.0	COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,42MDF@68525|delta/epsilon subdivisions,2YMNI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Pseudouridine synthase	sfhB	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
k59_177953_1	1249480.B649_08850	2.54e-130	385.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,42MPH@68525|delta/epsilon subdivisions,2YMZ9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	N-acetylmuramoyl-L-alanine amidase	amiA	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
k59_531057_1	709032.Sulku_0835	2.37e-139	420.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2YNQF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0474 Cation transport ATPase	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3,Na_H_Exchanger
k59_531057_2	709032.Sulku_1378	1.03e-77	233.0	COG1959@1|root,COG1959@2|Bacteria,1MZ1C@1224|Proteobacteria,42SPF@68525|delta/epsilon subdivisions	1224|Proteobacteria	K	TIGRFAM transcriptional regulator, Rrf2 family	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
k59_1469428_1	387093.SUN_0188	3.55e-80	239.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,42SD5@68525|delta/epsilon subdivisions,2YP70@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
k59_1293756_1	1537917.JU82_09335	2.35e-54	173.0	COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,42V63@68525|delta/epsilon subdivisions,2YT0N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
k59_1293756_2	1537917.JU82_09340	7.06e-43	145.0	2A1M6@1|root,30PVA@2|Bacteria,1QTJ9@1224|Proteobacteria,42VDW@68525|delta/epsilon subdivisions,2YQIZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
k59_531063_1	563040.Saut_1223	5.5e-32	127.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42MXI@68525|delta/epsilon subdivisions,2YTK8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
k59_61003_1	1537917.JU82_00745	3.87e-21	85.1	2AJR0@1|root,31AD0@2|Bacteria,1Q5D2@1224|Proteobacteria,43120@68525|delta/epsilon subdivisions,2YS7W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1354221_1	1249480.B649_11300	1.64e-47	161.0	2AIAA@1|root,318R4@2|Bacteria,1Q0T4@1224|Proteobacteria,42SFV@68525|delta/epsilon subdivisions,2YPR6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	1.13.11.63	ko:K21817	-	-	-	-	ko00000,ko01000	-	-	-	-
k59_1354221_2	1249480.B649_11305	2.38e-35	133.0	COG3278@1|root,COG3278@2|Bacteria,1QAUQ@1224|Proteobacteria,42P3Q@68525|delta/epsilon subdivisions,2YNBX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the heme-copper respiratory oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	COX1
k59_1531621_1	1263831.F543_22270	5.34e-62	213.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,1RNW3@1236|Gammaproteobacteria,1Y71M@135625|Pasteurellales	135625|Pasteurellales	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
k59_591359_1	1500301.JQMF01000006_gene1773	2.41e-49	180.0	COG5108@1|root,COG5108@2|Bacteria,1PIWB@1224|Proteobacteria,2U1JR@28211|Alphaproteobacteria,4BC0X@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	DNA-directed RNA polymerase N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	RNA_pol,RPOL_N
k59_1706747_1	387093.SUN_0471	2.67e-184	523.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,42MXN@68525|delta/epsilon subdivisions,2YN93@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EH	anthranilate synthase component	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP1282	Anth_synt_I_N,Chorismate_bind
k59_1354247_1	1249480.B649_07595	5.83e-65	213.0	COG1538@1|root,COG1538@2|Bacteria,1QWWG@1224|Proteobacteria,42PH5@68525|delta/epsilon subdivisions,2YMHH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_5899_2	709032.Sulku_2287	3.94e-76	228.0	COG0853@1|root,COG0853@2|Bacteria,1RI1B@1224|Proteobacteria,42SBM@68525|delta/epsilon subdivisions,2YPGH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
k59_5899_3	563040.Saut_0300	9.01e-20	82.0	COG0718@1|root,COG0718@2|Bacteria,1Q3T8@1224|Proteobacteria,42UGW@68525|delta/epsilon subdivisions,2YPUE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	ybaB	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
k59_1002700_1	159087.Daro_2972	7.46e-55	191.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,2VHBJ@28216|Betaproteobacteria,2KUXR@206389|Rhodocyclales	206389|Rhodocyclales	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
k59_1648082_1	1244531.CIG1485E_0064	9.64e-49	166.0	COG0381@1|root,COG0381@2|Bacteria,1MWZN@1224|Proteobacteria,43B4D@68525|delta/epsilon subdivisions,2YMS6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
k59_1648082_2	32024.JMTI01000008_gene1080	4.2e-39	134.0	COG0677@1|root,COG0677@2|Bacteria,1QV0P@1224|Proteobacteria,43BN8@68525|delta/epsilon subdivisions,2YNJZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.336	ko:K02472	ko00520,ko05111,map00520,map05111	-	R03317	RC00291	ko00000,ko00001,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_1471794_1	1249480.B649_10120	1.49e-164	482.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2YMI5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	cation transport ATPase	ccoI	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
k59_651269_1	553385.JEMF01000002_gene2834	2.73e-29	108.0	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,1SCG6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	yidD	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0031224,GO:0031226,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
k59_651269_2	1121004.ATVC01000056_gene631	4.84e-24	100.0	COG0044@1|root,COG0044@2|Bacteria,1PP53@1224|Proteobacteria,2W9F4@28216|Betaproteobacteria,2KTAT@206351|Neisseriales	206351|Neisseriales	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
k59_297305_1	84531.JMTZ01000096_gene709	8.38e-64	213.0	COG4579@1|root,COG4579@2|Bacteria,1MVRB@1224|Proteobacteria,1RMC2@1236|Gammaproteobacteria,1X3M4@135614|Xanthomonadales	135614|Xanthomonadales	F	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation	aceK	GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004721,GO:0005488,GO:0005524,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009987,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0017076,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	2.7.11.5	ko:K00906	-	-	-	-	ko00000,ko01000	-	-	-	AceK
k59_944103_1	158500.BV97_04548	3.68e-50	175.0	COG1231@1|root,COG1231@2|Bacteria,1RA9M@1224|Proteobacteria,2TTDV@28211|Alphaproteobacteria,2K25J@204457|Sphingomonadales	204457|Sphingomonadales	E	Flavin containing amine oxidoreductase	-	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
k59_121890_1	1488328.JMCL01000124_gene2787	1.99e-105	328.0	COG0497@1|root,COG0497@2|Bacteria,1QUWK@1224|Proteobacteria,1RRCE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_13,AAA_21,AAA_23
k59_62829_1	1165841.SULAR_02033	1.36e-72	232.0	2A54K@1|root,30TT8@2|Bacteria,1Q98H@1224|Proteobacteria,4348V@68525|delta/epsilon subdivisions,2YRCN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1648128_1	796940.HMPREF9628_00289	6.04e-20	88.2	COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,248QF@186801|Clostridia,25QJU@186804|Peptostreptococcaceae	186801|Clostridia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
k59_1648128_2	749222.Nitsa_0299	2.38e-48	155.0	COG1145@1|root,COG1145@2|Bacteria,1QUJB@1224|Proteobacteria,42TSI@68525|delta/epsilon subdivisions,2YPU2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Ferredoxin	fdxA	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
k59_1784324_1	243233.MCA2110	3.78e-09	58.9	COG1538@1|root,COG1538@2|Bacteria,1R744@1224|Proteobacteria,1SZYN@1236|Gammaproteobacteria,1XGYJ@135618|Methylococcales	135618|Methylococcales	MU	Outer membrane efflux protein	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
k59_674580_1	159087.Daro_4199	5.06e-37	136.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,2VKW1@28216|Betaproteobacteria,2KVYF@206389|Rhodocyclales	206389|Rhodocyclales	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
k59_1608202_1	1249480.B649_08710	1.73e-113	333.0	COG3034@1|root,COG3034@2|Bacteria,1N2B6@1224|Proteobacteria,42QS4@68525|delta/epsilon subdivisions,2YNYQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	ErfK YbiS YcfS YnhG family protein	pgp2	-	-	-	-	-	-	-	-	-	-	-	YkuD
k59_144597_2	387093.SUN_1078	1.25e-48	164.0	COG1633@1|root,COG1633@2|Bacteria,1Q0JN@1224|Proteobacteria,42S76@68525|delta/epsilon subdivisions,2YP4Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1197061_1	159087.Daro_2878	2.35e-102	303.0	COG0491@1|root,COG0491@2|Bacteria,1MY6G@1224|Proteobacteria,2VIK0@28216|Betaproteobacteria,2KVSE@206389|Rhodocyclales	206389|Rhodocyclales	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_1197061_2	1255043.TVNIR_0579	1.69e-08	53.1	COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,1S3QM@1236|Gammaproteobacteria,1WYBE@135613|Chromatiales	135613|Chromatiales	S	Belongs to the UPF0178 family	-	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
k59_1491490_2	1165841.SULAR_01958	1.09e-28	115.0	COG1233@1|root,COG1233@2|Bacteria,1P0N4@1224|Proteobacteria,42NRZ@68525|delta/epsilon subdivisions,2YMGH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8
k59_1081672_1	566466.NOR53_11	1.98e-33	124.0	COG1309@1|root,COG1309@2|Bacteria,1R7JI@1224|Proteobacteria	1224|Proteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_1081672_2	977880.RALTA_B0377	7.32e-37	134.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VZK0@28216|Betaproteobacteria,1K4Q1@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_433638_1	1537917.JU82_08345	9.82e-55	174.0	COG3018@1|root,COG3018@2|Bacteria,1RGG9@1224|Proteobacteria,42P0S@68525|delta/epsilon subdivisions,2YQJK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	(Lipo)protein	-	-	-	ko:K09860	-	-	-	-	ko00000	-	-	-	LPP20
k59_433638_2	709032.Sulku_2085	1.3e-34	124.0	2BR51@1|root,32K31@2|Bacteria,1Q8HX@1224|Proteobacteria,433KM@68525|delta/epsilon subdivisions,2YSI4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1142703_1	1327982.S0A2L1_9CAUD	6.81e-70	226.0	4QAIJ@10239|Viruses,4QVZ9@35237|dsDNA viruses  no RNA stage,4QPXI@28883|Caudovirales,4QM02@10699|Siphoviridae	10699|Siphoviridae	S	C-5 cytosine-specific DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_904055_1	640081.Dsui_2770	1.95e-70	232.0	COG4953@1|root,COG4953@2|Bacteria,1MUA9@1224|Proteobacteria,2VMGW@28216|Betaproteobacteria,2KVV8@206389|Rhodocyclales	206389|Rhodocyclales	M	Transglycosylase	-	-	2.4.1.129	ko:K05367	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	BiPBP_C,Transgly,Transpeptidase
k59_1197096_1	1537917.JU82_10615	4.56e-95	291.0	COG1032@1|root,COG1032@2|Bacteria,1Q5NG@1224|Proteobacteria,42N2D@68525|delta/epsilon subdivisions,2YNAR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4080,Radical_SAM
k59_144675_1	159087.Daro_3033	3.56e-100	301.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,2VHEB@28216|Betaproteobacteria,2KUN2@206389|Rhodocyclales	206389|Rhodocyclales	E	acetylornithine aminotransferase	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_258563_1	1304883.KI912532_gene2772	6.66e-84	267.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2VMTA@28216|Betaproteobacteria,2M00C@206389|Rhodocyclales	206389|Rhodocyclales	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctM,DctQ
k59_258563_2	159087.Daro_3577	1.43e-33	124.0	COG1638@1|root,COG1638@2|Bacteria,1PMWE@1224|Proteobacteria,2VNJI@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k59_1848462_1	90814.KL370891_gene846	1.68e-109	332.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1SYRX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Protoglobin
k59_144685_1	367737.Abu_1728	9.63e-59	206.0	COG3437@1|root,COG3437@2|Bacteria,1QUN9@1224|Proteobacteria,42PHR@68525|delta/epsilon subdivisions,2YMDI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C,HD,PAS_3,PAS_9,Response_reg
k59_1197130_1	387093.SUN_0587	3.76e-40	146.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,42MYN@68525|delta/epsilon subdivisions,2YMXA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	molybdopterin oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin,Molydop_binding
k59_1197130_2	1165841.SULAR_00175	8.64e-74	227.0	COG1566@1|root,COG1566@2|Bacteria,1QYCU@1224|Proteobacteria,42TB0@68525|delta/epsilon subdivisions,2YPDT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	PFAM secretion protein HlyD family protein	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3
k59_786948_1	929558.SMGD1_2763	3.85e-94	296.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YNJ4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_904137_1	580332.Slit_1860	8.84e-112	327.0	COG1028@1|root,COG1028@2|Bacteria,1MUSQ@1224|Proteobacteria,2VM6G@28216|Betaproteobacteria	28216|Betaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	ko:K13775	ko00281,map00281	-	R08087,R08096,R10125,R10126	RC00080,RC00087	ko00000,ko00001	-	-	-	adh_short
k59_612999_1	1304883.KI912532_gene732	3.94e-76	228.0	COG5341@1|root,COG5341@2|Bacteria,1N1PN@1224|Proteobacteria,2VUW8@28216|Betaproteobacteria,2KWYI@206389|Rhodocyclales	206389|Rhodocyclales	S	NusG domain II	-	-	-	-	-	-	-	-	-	-	-	-	NusG_II
k59_612999_2	159087.Daro_0068	7.21e-20	84.0	COG4769@1|root,COG4769@2|Bacteria,1RJIB@1224|Proteobacteria,2VRM1@28216|Betaproteobacteria,2KWG1@206389|Rhodocyclales	206389|Rhodocyclales	S	Heptaprenyl diphosphate synthase component I	-	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	Hpre_diP_synt_I
k59_847103_1	159087.Daro_4200	9.34e-104	312.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,2VHCJ@28216|Betaproteobacteria,2KVKC@206389|Rhodocyclales	206389|Rhodocyclales	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
k59_1608329_1	1249480.B649_06280	3.37e-117	342.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,42MJ0@68525|delta/epsilon subdivisions,2YMCZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Co Zn Cd efflux system component	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux,ZT_dimer
k59_199244_1	1304883.KI912532_gene545	3.31e-38	137.0	COG2207@1|root,COG2207@2|Bacteria,1R4MG@1224|Proteobacteria,2VISE@28216|Betaproteobacteria,2KVGP@206389|Rhodocyclales	206389|Rhodocyclales	K	Arabinose-binding domain of AraC transcription regulator, N-term	-	-	-	-	-	-	-	-	-	-	-	-	Arabinose_bd,HTH_18
k59_199244_2	522306.CAP2UW1_0492	5.42e-29	114.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,2VH05@28216|Betaproteobacteria,1KQDH@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
k59_786989_1	709032.Sulku_1430	2.9e-79	238.0	COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,42SN2@68525|delta/epsilon subdivisions,2YPEC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase	kdsC	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
k59_722491_1	709032.Sulku_2316	3.22e-169	488.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,42KZC@68525|delta/epsilon subdivisions,2YM82@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
k59_1374155_1	1249480.B649_06585	1.37e-08	54.7	COG0454@1|root,COG0456@2|Bacteria,1Q9FS@1224|Proteobacteria,42YQT@68525|delta/epsilon subdivisions,2YRH5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
k59_1374155_2	1249480.B649_06590	4.8e-126	367.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MSP@68525|delta/epsilon subdivisions,2YNBC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.14	ko:K02594	ko00620,map00620	-	R00271	RC00004,RC00067,RC02754	ko00000,ko00001,ko01000	-	-	-	HMGL-like
k59_1311853_1	595537.Varpa_2058	7.12e-16	77.8	COG0810@1|root,COG0810@2|Bacteria,1MZPX@1224|Proteobacteria,2VM32@28216|Betaproteobacteria,4AD9Q@80864|Comamonadaceae	28216|Betaproteobacteria	M	TIGRFAM TonB family protein	tonB	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
k59_1311853_2	757424.Hsero_0605	3.41e-07	53.1	COG0811@1|root,COG0811@2|Bacteria,1NMPB@1224|Proteobacteria,2VJ4U@28216|Betaproteobacteria,47302@75682|Oxalobacteraceae	28216|Betaproteobacteria	U	Biopolymer transport	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k59_613062_1	1304883.KI912532_gene845	2.68e-114	332.0	COG0500@1|root,COG0500@2|Bacteria,1QVBW@1224|Proteobacteria,2VQY2@28216|Betaproteobacteria,2KW7E@206389|Rhodocyclales	206389|Rhodocyclales	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
k59_144797_1	1132855.KB913035_gene426	6.46e-100	302.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,2KM9J@206350|Nitrosomonadales	206350|Nitrosomonadales	T	TIGRFAM nitrogen regulation protein NR(I)	-	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_1142874_1	76114.ebA833	2.55e-104	325.0	COG0380@1|root,COG0561@1|root,COG0380@2|Bacteria,COG0561@2|Bacteria,1MUIY@1224|Proteobacteria,2W9UN@28216|Betaproteobacteria,2KYW0@206389|Rhodocyclales	206389|Rhodocyclales	G	Glycosyltransferase family 20	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_20
k59_1142889_2	1120973.AQXL01000105_gene2570	1.76e-21	93.6	COG0640@1|root,COG3860@1|root,COG0640@2|Bacteria,COG3860@2|Bacteria,1V1C5@1239|Firmicutes,4HG15@91061|Bacilli,279N9@186823|Alicyclobacillaceae	91061|Bacilli	K	Uncharacterized protein conserved in bacteria (DUF2087)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2087,HTH_20,HTH_5
k59_1142890_1	1537917.JU82_04750	1.96e-193	543.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,42PNF@68525|delta/epsilon subdivisions,2YNCZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	Multicopper oxidase	-	-	1.16.3.3	ko:K22348	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
k59_1437450_1	159087.Daro_1536	9.58e-101	297.0	COG1018@1|root,COG1018@2|Bacteria,1MW37@1224|Proteobacteria,2WGQC@28216|Betaproteobacteria,2KZX1@206389|Rhodocyclales	206389|Rhodocyclales	C	Oxidoreductase FAD-binding domain	-	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	FAD_binding_6,NAD_binding_1
k59_904221_1	159087.Daro_0269	1.5e-12	68.2	COG0454@1|root,COG0456@2|Bacteria,1R8GF@1224|Proteobacteria,2VNUV@28216|Betaproteobacteria	28216|Betaproteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,PilZ
k59_1555063_1	1537917.JU82_00225	3.49e-37	136.0	COG3437@1|root,COG3437@2|Bacteria,1QYD6@1224|Proteobacteria,43CBH@68525|delta/epsilon subdivisions,2YTB6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	cheY-homologous receiver domain	-	-	3.1.1.61,3.5.1.44	ko:K03412,ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	Response_reg
k59_1555063_2	709032.Sulku_1958	1.75e-71	216.0	COG0745@1|root,COG0745@2|Bacteria,1QZ26@1224|Proteobacteria,42SJU@68525|delta/epsilon subdivisions,2YPGY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
k59_1555063_3	1537917.JU82_00215	7.42e-93	273.0	COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,42SWG@68525|delta/epsilon subdivisions,2YPN8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Chemotaxis protein CheW	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
k59_1555063_4	709032.Sulku_1956	4.92e-39	151.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42N03@68525|delta/epsilon subdivisions,2YNMG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	PFAM Methyl-accepting chemotaxis protein (MCP) signaling domain	-	-	-	ko:K03406,ko:K05875	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,MCPsignal
k59_557906_1	870187.Thini_0169	7.79e-93	284.0	COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,1RYJX@1236|Gammaproteobacteria,46213@72273|Thiotrichales	72273|Thiotrichales	G	Ribulose bisphosphate carboxylase large chain, catalytic domain	-	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
k59_1261988_1	59538.XP_005975274.1	2.03e-92	299.0	COG0085@1|root,KOG0214@2759|Eukaryota	2759|Eukaryota	K	DNA-directed 5'-3' RNA polymerase activity	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0030880,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043,ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_965324_1	709032.Sulku_2454	2.36e-108	317.0	COG0791@1|root,COG0791@2|Bacteria,1RBV6@1224|Proteobacteria,42RZU@68525|delta/epsilon subdivisions,2YPA6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_4
k59_373850_1	1537917.JU82_08075	5.23e-110	320.0	COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,1MXYZ@1224|Proteobacteria,42M4E@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Protein of unknown function (DUF1722)	ybgA	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
k59_904265_1	1165841.SULAR_06238	2.06e-23	94.4	COG1587@1|root,COG1587@2|Bacteria,1NMTP@1224|Proteobacteria,42RBA@68525|delta/epsilon subdivisions,2YP0J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Uroporphyrinogen-III synthase	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
k59_904265_2	1165841.SULAR_06233	1.51e-19	86.7	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,42MCI@68525|delta/epsilon subdivisions,2YMR4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
k59_313692_1	709032.Sulku_1124	8.32e-31	117.0	COG1352@1|root,COG1352@2|Bacteria,1MVP3@1224|Proteobacteria,42PR6@68525|delta/epsilon subdivisions,2YNJY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	methyltransferase	cheR	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
k59_313692_2	709032.Sulku_1123	3.59e-66	208.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,42M27@68525|delta/epsilon subdivisions,2YP5K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	protein-glutamate methylesterase	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest
k59_313692_3	525897.Dbac_0632	3.52e-27	111.0	COG3437@1|root,COG4252@1|root,COG3437@2|Bacteria,COG4252@2|Bacteria,1QUNZ@1224|Proteobacteria	1224|Proteobacteria	KT	PFAM CHASE2 domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,SpoIIE
k59_199397_1	305700.B447_20126	2.58e-17	82.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2VQI1@28216|Betaproteobacteria,2KXTQ@206389|Rhodocyclales	206389|Rhodocyclales	T	COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
k59_199397_2	243365.CV_3248	1.59e-29	122.0	COG0642@1|root,COG3437@1|root,COG3829@1|root,COG0642@2|Bacteria,COG3437@2|Bacteria,COG3829@2|Bacteria,1NXDJ@1224|Proteobacteria,2W1GY@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,CHASE,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_7,PAS_8,Response_reg
k59_904269_1	159087.Daro_0254	5.49e-24	97.4	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2VHET@28216|Betaproteobacteria,2KUVN@206389|Rhodocyclales	206389|Rhodocyclales	E	ABC-type branched-chain amino acid transport systems, ATPase component	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
k59_904269_2	159087.Daro_0253	1.78e-119	352.0	COG0683@1|root,COG0683@2|Bacteria,1MV5T@1224|Proteobacteria,2VI33@28216|Betaproteobacteria,2KVMF@206389|Rhodocyclales	206389|Rhodocyclales	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_258760_1	349520.PPE_00444	1.03e-14	79.0	COG0642@1|root,COG2199@1|root,COG2972@1|root,COG2205@2|Bacteria,COG2972@2|Bacteria,COG3706@2|Bacteria,1TRIG@1239|Firmicutes,4HD8X@91061|Bacilli,26QIJ@186822|Paenibacillaceae	91061|Bacilli	T	Histidine kinase	ywpD	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,HATPase_c,HisKA,His_kinase,Response_reg
k59_1311964_1	1165841.SULAR_08582	3.23e-85	261.0	COG0477@1|root,COG2814@2|Bacteria,1MVZI@1224|Proteobacteria,42P57@68525|delta/epsilon subdivisions,2YMGG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EGP	Major facilitator superfamily	-	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1_like
k59_787180_1	1537917.JU82_06190	2.69e-80	239.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,42MND@68525|delta/epsilon subdivisions,2YMH3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	serine acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep
k59_787180_2	709032.Sulku_2550	9.72e-17	77.8	2C2AA@1|root,2ZAYY@2|Bacteria,1RD8I@1224|Proteobacteria,42N13@68525|delta/epsilon subdivisions,2YN8K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	TraT complement resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	TraT
k59_78973_1	709032.Sulku_2027	3.66e-92	279.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,42MIH@68525|delta/epsilon subdivisions,2YRA4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing EAL and modified HD-GYP domains	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_1374318_1	1165841.SULAR_02748	7.02e-235	657.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,42M81@68525|delta/epsilon subdivisions,2YMTF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_496438_1	1190606.AJYG01000047_gene1056	1.29e-49	180.0	COG2984@1|root,COG5001@1|root,COG2984@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XU9M@135623|Vibrionales	135623|Vibrionales	T	Sensory box GGDEF family protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,EAL,GGDEF,PAS_8,PAS_9
k59_1262123_2	1288494.EBAPG3_14180	1.43e-40	138.0	2CFNW@1|root,32S25@2|Bacteria,1NY05@1224|Proteobacteria,2WBKV@28216|Betaproteobacteria,373CK@32003|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_613288_1	159087.Daro_0755	2.33e-89	268.0	COG2063@1|root,COG2063@2|Bacteria,1RDEY@1224|Proteobacteria,2VRIC@28216|Betaproteobacteria,2KWEC@206389|Rhodocyclales	206389|Rhodocyclales	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgH	-	-	ko:K02393	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgH
k59_613288_2	159087.Daro_0754	2.09e-49	164.0	COG4786@1|root,COG4786@2|Bacteria,1MVMA@1224|Proteobacteria,2VH7A@28216|Betaproteobacteria,2KVFS@206389|Rhodocyclales	206389|Rhodocyclales	N	Belongs to the flagella basal body rod proteins family	flgG	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k59_1491772_1	159087.Daro_3942	5.8e-111	330.0	COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,2VIX5@28216|Betaproteobacteria,2KUZ4@206389|Rhodocyclales	206389|Rhodocyclales	M	Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate	mpl	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_1491772_2	159087.Daro_3941	4.59e-21	87.8	COG2413@1|root,COG2413@2|Bacteria,1RFTH@1224|Proteobacteria,2VJC9@28216|Betaproteobacteria,2KUIR@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1851474_2	1537917.JU82_07630	9.33e-31	117.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,42MBA@68525|delta/epsilon subdivisions,2YMBD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_1313708_1	1121296.JONJ01000008_gene462	2.98e-56	201.0	COG0030@1|root,COG0438@1|root,COG1216@1|root,COG0030@2|Bacteria,COG0438@2|Bacteria,COG1216@2|Bacteria,1TQTM@1239|Firmicutes,24A9R@186801|Clostridia,21Z2M@1506553|Lachnoclostridium	186801|Clostridia	M	Glycosyltransferase like family	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_trans_1_4,Glycos_transf_2
k59_1376419_1	1249480.B649_07115	1.01e-84	270.0	COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,42PHY@68525|delta/epsilon subdivisions,2YMBI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG0155 Sulfite reductase, beta subunit (hemoprotein)	-	-	1.7.7.1,1.8.7.1	ko:K00366,ko:K00392	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00531	R00790,R00859,R03600	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
k59_1610559_1	41431.PCC8801_4349	2.01e-06	54.7	COG0642@1|root,COG5001@1|root,COG2205@2|Bacteria,COG5001@2|Bacteria,1G09B@1117|Cyanobacteria,3KGK5@43988|Cyanothece	1117|Cyanobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,HisKA_2,PAS_3,PAS_4,PAS_9,Response_reg
k59_906277_1	1304883.KI912532_gene541	7.93e-245	685.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,2VI0U@28216|Betaproteobacteria,2KV98@206389|Rhodocyclales	206389|Rhodocyclales	I	AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
k59_1084160_1	864051.BurJ1DRAFT_3311	1.71e-72	228.0	COG3302@1|root,COG3302@2|Bacteria,1MWY1@1224|Proteobacteria,2VN4W@28216|Betaproteobacteria,1KKQ5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	DMSO reductase anchor subunit (DmsC)	dmsC	-	-	ko:K21309	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R11487	RC00168	ko00000,ko00001	-	-	-	DmsC
k59_1084162_2	1123326.JFBL01000003_gene1983	4.57e-32	122.0	COG0038@1|root,COG0038@2|Bacteria,1MV4K@1224|Proteobacteria,42N93@68525|delta/epsilon subdivisions,2YMRH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	Voltage_CLC
k59_616241_1	1165841.SULAR_00690	3.84e-147	446.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YNNQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1145757_1	545694.TREPR_0022	7.23e-27	106.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_11,Methyltransf_25
k59_1145757_2	269798.CHU_2765	0.000138	45.1	COG0399@1|root,COG0399@2|Bacteria,4NFQ8@976|Bacteroidetes,47K8X@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	pseC	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
k59_1851516_1	338969.Rfer_3633	1.02e-10	61.2	2C99Z@1|root,2Z9YV@2|Bacteria,1N0B7@1224|Proteobacteria,2W15Y@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3373)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3373
k59_1851516_2	1304883.KI912532_gene862	7.49e-42	140.0	2E66J@1|root,330V5@2|Bacteria,1NEPZ@1224|Proteobacteria,2W4M5@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1145767_1	709032.Sulku_0146	6.44e-93	281.0	COG1533@1|root,COG1533@2|Bacteria,1NWJ9@1224|Proteobacteria,42P30@68525|delta/epsilon subdivisions,2YNT6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	radical SAM domain protein	-	-	4.1.99.14	ko:K03716	-	-	-	-	ko00000,ko01000	-	-	-	-
k59_499089_1	765913.ThidrDRAFT_1203	1.09e-25	104.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RMA9@1236|Gammaproteobacteria,1WXA2@135613|Chromatiales	135613|Chromatiales	T	TIGRFAM Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_3,Response_reg
k59_1376468_1	1537917.JU82_03585	2.16e-81	244.0	COG2824@1|root,COG2824@2|Bacteria,1RGUU@1224|Proteobacteria,42V18@68525|delta/epsilon subdivisions,2YQGA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Zn-ribbon-containing protein involved in phosphonate metabolism	phnA	-	-	ko:K06193	ko01120,map01120	-	-	-	ko00000	-	-	-	PhnA,PhnA_Zn_Ribbon
k59_1376468_2	319224.Sputcn32_3856	2.2e-26	109.0	COG3614@1|root,COG3829@1|root,COG5001@1|root,COG3614@2|Bacteria,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2Q8QJ@267890|Shewanellaceae	1236|Gammaproteobacteria	T	SMART PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GGDEF,MASE1,PAS_9,Response_reg
k59_906320_1	1537917.JU82_01830	1.26e-28	112.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,42MEF@68525|delta/epsilon subdivisions,2YMMY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Aminotransferase	-	-	-	ko:K14261	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_410282_2	1163617.SCD_n00969	1.5e-49	173.0	COG0484@1|root,COG0484@2|Bacteria,1MXM9@1224|Proteobacteria,2VPQ6@28216|Betaproteobacteria	28216|Betaproteobacteria	C	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII
k59_410301_1	709032.Sulku_0299	2.83e-61	199.0	2BQX9@1|root,32JUG@2|Bacteria,1Q2H0@1224|Proteobacteria,42VPF@68525|delta/epsilon subdivisions,2YQMK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_755689_1	159087.Daro_3461	3.85e-98	295.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2VJR5@28216|Betaproteobacteria,2KUCZ@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
k59_755690_1	709032.Sulku_1931	5.42e-153	450.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,42M2T@68525|delta/epsilon subdivisions,2YMF5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	ATP-dependent CLP protease ATP-binding subunit	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_880452_2	1168067.JAGP01000001_gene663	2.43e-41	138.0	COG0278@1|root,COG0278@2|Bacteria,1MZ4V@1224|Proteobacteria,1S640@1236|Gammaproteobacteria,460ZB@72273|Thiotrichales	72273|Thiotrichales	C	Belongs to the glutaredoxin family. Monothiol subfamily	-	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin
k59_755738_1	1565314.OA34_10480	5.18e-06	53.5	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42YK0@68525|delta/epsilon subdivisions,2YRI7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
k59_1818703_1	709032.Sulku_2099	1.03e-51	177.0	COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,42MCZ@68525|delta/epsilon subdivisions,2YMYT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	type I secretion membrane fusion protein, HlyD family	-	-	-	ko:K12542,ko:K16300	-	M00330,M00571	-	-	ko00000,ko00002,ko02000,ko02044	3.A.1.109.4,8.A.1,8.A.1.3.3	-	-	Biotin_lipoyl_2,HlyD,HlyD_3
k59_1818703_2	709032.Sulku_2100	1.68e-05	46.2	COG4618@1|root,COG4618@2|Bacteria,1NTI5@1224|Proteobacteria,43BND@68525|delta/epsilon subdivisions,2YN2R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K16299	ko02010,map02010	M00571	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.110.10	-	-	ABC_membrane,ABC_tran
k59_880539_1	749222.Nitsa_0862	2.63e-65	220.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,42M6W@68525|delta/epsilon subdivisions,2YN2C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	spoT	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT,HD_4,RelA_SpoT,TGS
k59_755811_2	1537917.JU82_00260	1.25e-25	99.4	COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,42R30@68525|delta/epsilon subdivisions,2YNU1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
k59_349953_1	367737.Abu_0527	1.27e-54	174.0	2BMN0@1|root,32G77@2|Bacteria,1Q0X8@1224|Proteobacteria,42SM0@68525|delta/epsilon subdivisions,2YPGW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_112211_1	1089548.KI783301_gene3309	2.41e-36	124.0	2AU0F@1|root,31JKB@2|Bacteria,1V6XX@1239|Firmicutes,4HWBB@91061|Bacilli	91061|Bacilli	S	COG NOG14600 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1818842_1	1249480.B649_07615	1.09e-75	244.0	COG1315@1|root,COG1315@2|Bacteria,1R5P6@1224|Proteobacteria,42MAS@68525|delta/epsilon subdivisions,2YM7Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Flagellar Assembly Protein A	-	-	-	-	-	-	-	-	-	-	-	-	FapA
k59_410565_1	159087.Daro_2389	5.82e-146	423.0	COG0662@1|root,COG0836@1|root,COG0662@2|Bacteria,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,2VI4S@28216|Betaproteobacteria,2KUWY@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the mannose-6-phosphate isomerase type 2 family	algA	-	2.7.7.13,5.3.1.8	ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00362	R00885,R01819	RC00002,RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
k59_410565_2	7739.XP_002591298.1	6.65e-11	62.8	COG0484@1|root,KOG0712@2759|Eukaryota,38CPQ@33154|Opisthokonta,3BCGW@33208|Metazoa,3CS84@33213|Bilateria,481JQ@7711|Chordata	33208|Metazoa	O	regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway	DNAJA4	GO:0000003,GO:0001664,GO:0001671,GO:0001932,GO:0001933,GO:0003674,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0005829,GO:0005856,GO:0006457,GO:0006469,GO:0006810,GO:0006928,GO:0006950,GO:0006974,GO:0006986,GO:0007154,GO:0007165,GO:0007276,GO:0007283,GO:0008047,GO:0008104,GO:0008134,GO:0008150,GO:0009719,GO:0009725,GO:0009755,GO:0009892,GO:0009966,GO:0009968,GO:0009987,GO:0010033,GO:0010563,GO:0010605,GO:0010646,GO:0010648,GO:0010941,GO:0010942,GO:0012505,GO:0014070,GO:0015630,GO:0016020,GO:0019220,GO:0019222,GO:0019899,GO:0019904,GO:0019953,GO:0022414,GO:0023051,GO:0023052,GO:0023057,GO:0030234,GO:0030317,GO:0030518,GO:0030521,GO:0030522,GO:0030544,GO:0030957,GO:0031072,GO:0031323,GO:0031324,GO:0031396,GO:0031397,GO:0031399,GO:0031400,GO:0031625,GO:0031984,GO:0032268,GO:0032269,GO:0032501,GO:0032504,GO:0032781,GO:0032870,GO:0032872,GO:0032873,GO:0032879,GO:0032880,GO:0033036,GO:0033365,GO:0033554,GO:0033673,GO:0033993,GO:0034613,GO:0035966,GO:0040011,GO:0042026,GO:0042175,GO:0042221,GO:0042325,GO:0042326,GO:0042769,GO:0042981,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043085,GO:0043086,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043401,GO:0043405,GO:0043407,GO:0043408,GO:0043409,GO:0043462,GO:0043506,GO:0043508,GO:0043549,GO:0044087,GO:0044092,GO:0044093,GO:0044389,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045859,GO:0045936,GO:0046328,GO:0046329,GO:0048232,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048545,GO:0048583,GO:0048585,GO:0048609,GO:0048870,GO:0050750,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051049,GO:0051082,GO:0051087,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051174,GO:0051179,GO:0051223,GO:0051234,GO:0051246,GO:0051248,GO:0051336,GO:0051338,GO:0051345,GO:0051348,GO:0051606,GO:0051641,GO:0051674,GO:0051704,GO:0051716,GO:0055131,GO:0060255,GO:0060341,GO:0060548,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0070201,GO:0070302,GO:0070303,GO:0070325,GO:0070585,GO:0070727,GO:0070887,GO:0071310,GO:0071383,GO:0071396,GO:0071407,GO:0071495,GO:0071900,GO:0071901,GO:0080090,GO:0080134,GO:0080135,GO:0090083,GO:0090084,GO:0090087,GO:0097722,GO:0098552,GO:0098554,GO:0098562,GO:0098772,GO:0098827,GO:1901998,GO:1902531,GO:1902532,GO:1903320,GO:1903321,GO:1903747,GO:1903748,GO:1903827,GO:1903828,GO:1904950,GO:1905258,GO:1905259,GO:2001233,GO:2001234,GO:2001242,GO:2001243	-	ko:K09502,ko:K09503,ko:K09505	ko04141,map04141	-	-	-	ko00000,ko00001,ko03029,ko03110,ko04131	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
k59_410579_1	1407650.BAUB01000007_gene1490	6.22e-57	189.0	COG1228@1|root,COG1228@2|Bacteria,1G3PN@1117|Cyanobacteria,1H2T7@1129|Synechococcus	1117|Cyanobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
k59_112313_1	1537917.JU82_06725	1.55e-64	207.0	COG0618@1|root,COG0618@2|Bacteria,1RADZ@1224|Proteobacteria,43DQA@68525|delta/epsilon subdivisions,2YT8A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	DHH family	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
k59_112313_2	1537917.JU82_06730	2.29e-58	193.0	COG0739@1|root,COG0739@2|Bacteria,1NESH@1224|Proteobacteria,42MGB@68525|delta/epsilon subdivisions,2YMT7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_1818897_1	709032.Sulku_1923	4.55e-133	385.0	COG0795@1|root,COG0795@2|Bacteria,1PXEK@1224|Proteobacteria,42MVG@68525|delta/epsilon subdivisions,2YN6F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	permease	-	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_350120_1	1509403.GW12_11710	1.22e-26	110.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,1RNPY@1236|Gammaproteobacteria,3NK6N@468|Moraxellaceae	1236|Gammaproteobacteria	O	Peptidase family U32	yegQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
k59_350120_2	400668.Mmwyl1_1525	5.21e-23	89.4	COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,1S8ZV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Ferredoxin	yfhL	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
k59_410782_1	1537917.JU82_10995	3.24e-126	367.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,42N9Q@68525|delta/epsilon subdivisions,2YMUH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	iIT341.HP0921	Gp_dh_C,Gp_dh_N
k59_410797_1	1395587.P364_0104870	1.31e-53	190.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,26QWH@186822|Paenibacillaceae	91061|Bacilli	T	Diguanylate cyclase	-	-	2.7.7.65	ko:K21023	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	EAL,GGDEF,MHYT,PAS,PAS_4,PAS_9,Protoglobin
k59_410797_2	1537917.JU82_08000	1.67e-36	128.0	COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,42QQP@68525|delta/epsilon subdivisions,2YNZZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
k59_112465_1	1165841.SULAR_05148	9.38e-108	324.0	COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,42NTK@68525|delta/epsilon subdivisions,2YNFT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the UPF0061 (SELO) family	-	-	-	-	-	-	-	-	-	-	-	-	UPF0061
k59_756101_1	159087.Daro_1112	3.92e-77	244.0	COG3659@1|root,COG3659@2|Bacteria,1Q8C7@1224|Proteobacteria,2VJFC@28216|Betaproteobacteria,2KURR@206389|Rhodocyclales	206389|Rhodocyclales	M	Carbohydrate-selective porin, OprB family	-	-	-	-	-	-	-	-	-	-	-	-	OprB
k59_112496_1	709032.Sulku_0306	1.09e-101	304.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,42NF0@68525|delta/epsilon subdivisions,2YMRR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3
k59_350388_1	502025.Hoch_4314	2.69e-08	60.8	COG0845@1|root,COG0845@2|Bacteria,1MX8W@1224|Proteobacteria,42SYF@68525|delta/epsilon subdivisions,2WPNQ@28221|Deltaproteobacteria,2YZZ6@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
k59_410913_1	159087.Daro_0008	1.39e-66	228.0	COG0784@1|root,COG2198@1|root,COG5000@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG5000@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,2WGIN@28216|Betaproteobacteria,2KZWN@206389|Rhodocyclales	206389|Rhodocyclales	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_4,PAS_9,Response_reg
k59_1819103_1	443144.GM21_3507	2.39e-94	291.0	COG0438@1|root,COG0438@2|Bacteria,1R6BX@1224|Proteobacteria	1224|Proteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glycos_transf_1
k59_112556_1	395494.Galf_2362	4.74e-123	358.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,2VJ6H@28216|Betaproteobacteria,44VPF@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
k59_112566_1	395494.Galf_2806	5.02e-146	438.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,2VHQ6@28216|Betaproteobacteria,44V7J@713636|Nitrosomonadales	28216|Betaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
k59_54630_1	709032.Sulku_2370	4.85e-90	284.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42P9M@68525|delta/epsilon subdivisions,2YNH7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CZB,HAMP,MCPsignal,dCache_3
k59_1644225_2	709032.Sulku_1546	1.93e-92	275.0	2BV3K@1|root,32QGM@2|Bacteria,1Q4NH@1224|Proteobacteria,42ZI1@68525|delta/epsilon subdivisions,2YRN8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1526957_1	159087.Daro_4035	1.22e-93	280.0	COG4395@1|root,COG4395@2|Bacteria,1NSUG@1224|Proteobacteria,2VNS7@28216|Betaproteobacteria,2KV4Q@206389|Rhodocyclales	206389|Rhodocyclales	S	import inner membrane translocase subunit Tim44	-	-	-	-	-	-	-	-	-	-	-	-	Tim44
k59_1526996_2	1123073.KB899243_gene700	4.08e-104	317.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMIW@1236|Gammaproteobacteria,1X2ZH@135614|Xanthomonadales	135614|Xanthomonadales	J	Involved in the processing of the 5'end of 16S rRNA	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
k59_1703035_2	929558.SMGD1_0606	2.08e-14	72.8	COG2908@1|root,COG2908@2|Bacteria,1Q1QY@1224|Proteobacteria,42STS@68525|delta/epsilon subdivisions,2YP6A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	protein conserved in bacteria	lpxH	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos
k59_1409330_2	748247.AZKH_0682	8.65e-33	125.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,2VI41@28216|Betaproteobacteria,2KUFP@206389|Rhodocyclales	206389|Rhodocyclales	I	Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	clsB	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
k59_1057170_1	709032.Sulku_1905	4.11e-75	239.0	COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,42N4Y@68525|delta/epsilon subdivisions,2YNCE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase,Methyltransf_11,Methyltransf_31
k59_529086_1	929558.SMGD1_0430	2.21e-23	103.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42MV6@68525|delta/epsilon subdivisions	1224|Proteobacteria	NT	chemotaxis protein	cetA	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CZB,HAMP,MCPsignal,NIT
k59_646563_1	709032.Sulku_1317	2.2e-29	115.0	COG0835@1|root,COG0835@2|Bacteria,1QVCF@1224|Proteobacteria,42M0F@68525|delta/epsilon subdivisions,2YNAP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	PFAM CheW domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CheW,dCache_1
k59_646563_2	709032.Sulku_1317	4.36e-106	331.0	COG0835@1|root,COG0835@2|Bacteria,1QVCF@1224|Proteobacteria,42M0F@68525|delta/epsilon subdivisions,2YNAP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	PFAM CheW domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CheW,dCache_1
k59_646567_1	1304883.KI912532_gene1271	1.16e-89	276.0	COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,2VHRH@28216|Betaproteobacteria,2KVTC@206389|Rhodocyclales	206389|Rhodocyclales	C	IG-like fold at C-terminal of FixG, putative oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
k59_1585654_1	1121004.ATVC01000017_gene1865	1.62e-138	430.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,2VHUY@28216|Betaproteobacteria,2KPY3@206351|Neisseriales	28216|Betaproteobacteria	E	glutamate synthase	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_235442_1	1537917.JU82_02870	2.37e-73	229.0	2ANXW@1|root,31DYS@2|Bacteria,1MYQS@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1644298_1	1304883.KI912532_gene2149	5.46e-168	480.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,2VIP7@28216|Betaproteobacteria,2KUJQ@206389|Rhodocyclales	206389|Rhodocyclales	C	Catalyzes the reversible hydration of fumarate to (S)- malate	fumA	-	4.2.1.2	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase,Fumerase_C
k59_59329_1	1514668.JOOA01000002_gene2984	8.81e-15	80.5	COG0642@1|root,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,3WGVD@541000|Ruminococcaceae	186801|Clostridia	T	Response regulator receiver domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HD,HisKA,HisKA_7TM,Hpt,MASE3,PocR,Response_reg,dCache_1
k59_874_1	709032.Sulku_1139	1.92e-117	340.0	COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,42NZV@68525|delta/epsilon subdivisions,2YN88@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	ABC transporter permease	modB	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
k59_1703079_2	1537917.JU82_03320	1.32e-83	252.0	COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,42P58@68525|delta/epsilon subdivisions,2YN3D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	GO:0003674,GO:0005488,GO:0005515,GO:0042802	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
k59_1115902_1	159087.Daro_3881	2.26e-20	87.0	2C8XG@1|root,2Z7PK@2|Bacteria,1RA5I@1224|Proteobacteria,2VQGY@28216|Betaproteobacteria,2KW73@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
k59_1115902_2	159087.Daro_3882	1.8e-105	313.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,2VIWS@28216|Betaproteobacteria,2KU9J@206389|Rhodocyclales	206389|Rhodocyclales	NU	twitching motility protein	-	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_939899_1	159087.Daro_4201	3.92e-58	197.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,2VHIA@28216|Betaproteobacteria,2KUBX@206389|Rhodocyclales	206389|Rhodocyclales	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
k59_1468117_1	1537917.JU82_01150	2.82e-122	365.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2YMMT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_118070_2	709032.Sulku_0681	7.28e-63	203.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,42MJT@68525|delta/epsilon subdivisions,2YMEB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
k59_1292209_2	572480.Arnit_1535	4.69e-20	85.1	COG2337@1|root,COG2337@2|Bacteria,1Q23M@1224|Proteobacteria,42UXQ@68525|delta/epsilon subdivisions,2YPYA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
k59_1057232_2	159087.Daro_3026	9.86e-08	53.1	COG3577@1|root,COG3577@2|Bacteria,1N2PE@1224|Proteobacteria,2VS6Z@28216|Betaproteobacteria,2KWGP@206389|Rhodocyclales	206389|Rhodocyclales	S	gag-polyprotein putative aspartyl protease	-	-	-	ko:K06985	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	gag-asp_proteas
k59_1350795_2	1249480.B649_01820	1.15e-44	161.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YMHP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3
k59_118100_2	709032.Sulku_0471	1.87e-110	321.0	COG1776@1|root,COG1776@2|Bacteria,1N49I@1224|Proteobacteria,42UKN@68525|delta/epsilon subdivisions,2YQBN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	COGs COG1776 Chemotaxis protein CheC inhibitor of MCP methylation	-	-	-	ko:K03410	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheC,CheX
k59_964_2	1123401.JHYQ01000026_gene3243	1.62e-28	106.0	COG5501@1|root,COG5501@2|Bacteria,1N097@1224|Proteobacteria,1SCTJ@1236|Gammaproteobacteria,4619K@72273|Thiotrichales	72273|Thiotrichales	S	PFAM Sulphur oxidation protein SoxZ	-	-	-	ko:K17227	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxZ
k59_1350799_1	709032.Sulku_0756	2.15e-95	280.0	COG0712@1|root,COG0712@2|Bacteria,1RFPY@1224|Proteobacteria,42SKR@68525|delta/epsilon subdivisions,2YPHX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
k59_411656_1	1537917.JU82_01400	9.05e-54	190.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42PGT@68525|delta/epsilon subdivisions,2YNSH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	JM	Nucleotidyl transferase	-	-	2.7.7.71	ko:K15669	ko00540,map00540	-	R09772	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
k59_705139_1	1249480.B649_06395	4.19e-181	518.0	COG1166@1|root,COG1166@2|Bacteria,1MU80@1224|Proteobacteria,42M2B@68525|delta/epsilon subdivisions,2YMP0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	arginine decarboxylase	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0422	Orn_Arg_deC_N
k59_470440_1	1537917.JU82_02085	3.37e-77	252.0	COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,1QUIU@1224|Proteobacteria,42M7I@68525|delta/epsilon subdivisions,2YMX0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG3893 inactivated superfamily I helicase	addB	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
k59_1016_1	583345.Mmol_0564	9.09e-30	116.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,2VMTN@28216|Betaproteobacteria,2KM0U@206350|Nitrosomonadales	206350|Nitrosomonadales	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
k59_1016_2	666681.M301_0569	5.94e-42	151.0	COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,2VIV9@28216|Betaproteobacteria,2KKQY@206350|Nitrosomonadales	206350|Nitrosomonadales	D	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_587756_1	709032.Sulku_2224	4.38e-151	432.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,42MM1@68525|delta/epsilon subdivisions,2YN3A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	8-amino-7-oxononanoate synthase	bioF	-	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_470451_1	1249480.B649_05685	8.65e-12	60.8	COG5336@1|root,COG5336@2|Bacteria,1NHIS@1224|Proteobacteria,42VGZ@68525|delta/epsilon subdivisions,2YQ8C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
k59_470451_2	1249480.B649_05690	7.35e-211	589.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,42MBF@68525|delta/epsilon subdivisions,2YM9C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Glutamate-1-semialdehyde aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_705156_1	159087.Daro_1221	4.05e-155	444.0	COG1305@1|root,COG1305@2|Bacteria,1MY5V@1224|Proteobacteria,2VKGI@28216|Betaproteobacteria,2KW58@206389|Rhodocyclales	206389|Rhodocyclales	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
k59_1820754_1	709032.Sulku_1233	1.44e-195	556.0	COG1166@1|root,COG1166@2|Bacteria,1MU80@1224|Proteobacteria,42M2B@68525|delta/epsilon subdivisions,2YMP0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	arginine decarboxylase	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0422	Orn_Arg_deC_N
k59_998750_1	709032.Sulku_0841	4.37e-91	279.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42NVA@68525|delta/epsilon subdivisions,2YMYW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
k59_1115990_1	1123514.KB905899_gene993	4.62e-73	241.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,1RNAZ@1236|Gammaproteobacteria,460FW@72273|Thiotrichales	72273|Thiotrichales	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
k59_470460_2	1123326.JFBL01000001_gene1371	2.42e-34	130.0	COG0004@1|root,COG2199@1|root,COG0004@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,43D4C@68525|delta/epsilon subdivisions	1224|Proteobacteria	PT	Ammonium Transporter Family	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp,GGDEF,NMT1,SBP_bac_3
k59_294220_1	1304883.KI912532_gene2979	9.43e-166	488.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,2VJ5Q@28216|Betaproteobacteria,2KV41@206389|Rhodocyclales	206389|Rhodocyclales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_763771_1	1165841.SULAR_07123	3.89e-78	242.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,42N2T@68525|delta/epsilon subdivisions,2YNID@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	acid membrane antigen A	amaA	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k59_763771_2	387093.SUN_2094	1.26e-58	186.0	COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,42RGE@68525|delta/epsilon subdivisions,2YT0Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	PFAM response regulator receiver	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_1820792_2	387093.SUN_0435	1.69e-25	101.0	COG2843@1|root,COG2843@2|Bacteria,1RCV8@1224|Proteobacteria,42UIX@68525|delta/epsilon subdivisions,2YRGQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_4
k59_1080213_1	1249480.B649_07460	1.1e-111	333.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,42M28@68525|delta/epsilon subdivisions,2YMFV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
k59_1080213_2	1249480.B649_07455	5.22e-22	95.5	COG1315@1|root,COG1315@2|Bacteria,1R5P6@1224|Proteobacteria,42MAS@68525|delta/epsilon subdivisions,2YM7Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Flagellar Assembly Protein A	-	-	-	-	-	-	-	-	-	-	-	-	FapA
k59_1490282_1	1182553.XP_007747179.1	0.000171	48.9	COG0666@1|root,KOG4177@2759|Eukaryota,38BVK@33154|Opisthokonta,3NW9Q@4751|Fungi,3QJDH@4890|Ascomycota	4751|Fungi	M	ankyrin repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_4,Helo_like_N,NACHT
k59_963462_1	1249480.B649_10060	1.72e-89	284.0	COG1287@1|root,COG1287@2|Bacteria,1R481@1224|Proteobacteria,42MNZ@68525|delta/epsilon subdivisions,2YMU3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Oligosaccharyl transferase, STT3 subunit	pglB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0034645,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046872,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.4.99.18,2.4.99.19	ko:K07151,ko:K17251	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	STT3
k59_372382_1	159087.Daro_3727	8.2e-81	258.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,2VI6C@28216|Betaproteobacteria,2KUFQ@206389|Rhodocyclales	206389|Rhodocyclales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19
k59_197550_1	574966.KB898649_gene78	5.07e-29	110.0	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,1S41P@1236|Gammaproteobacteria,1XJI9@135619|Oceanospirillales	135619|Oceanospirillales	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
k59_197550_2	697282.Mettu_0889	1.63e-78	244.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,1RP4D@1236|Gammaproteobacteria,1XDTI@135618|Methylococcales	135618|Methylococcales	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_1724464_1	709032.Sulku_1851	2.11e-149	427.0	COG2070@1|root,COG2070@2|Bacteria,1N52W@1224|Proteobacteria,42N6F@68525|delta/epsilon subdivisions,2YMD6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	2-nitropropane dioxygenase	npd	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
k59_1724464_2	1249480.B649_08850	1.44e-34	132.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,42MPH@68525|delta/epsilon subdivisions,2YMZ9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	N-acetylmuramoyl-L-alanine amidase	amiA	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
k59_1080238_1	159087.Daro_3589	1.38e-123	359.0	COG0158@1|root,COG0158@2|Bacteria,1MW0E@1224|Proteobacteria,2VIJT@28216|Betaproteobacteria,2KUG8@206389|Rhodocyclales	206389|Rhodocyclales	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1	fbp	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
k59_1026341_1	59538.XP_005977984.1	9.43e-22	94.0	COG0187@1|root,COG1190@1|root,KOG0355@2759|Eukaryota,KOG1885@2759|Eukaryota,39WG1@33154|Opisthokonta,3BNSE@33208|Metazoa	33208|Metazoa	B	DNA gyrase C-terminal domain, beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_1026341_2	1442599.JAAN01000024_gene1958	2.62e-47	160.0	COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,1RMV7@1236|Gammaproteobacteria,1X4AM@135614|Xanthomonadales	135614|Xanthomonadales	H	O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway	ubiG	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23
k59_1141153_1	1123487.KB892863_gene1914	1.72e-61	207.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,2VN53@28216|Betaproteobacteria,2KVZK@206389|Rhodocyclales	206389|Rhodocyclales	I	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
k59_785204_1	1304883.KI912532_gene797	5.81e-58	204.0	COG0642@1|root,COG5000@1|root,COG5002@1|root,COG0642@2|Bacteria,COG5000@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2WGK9@28216|Betaproteobacteria,2KZW1@206389|Rhodocyclales	206389|Rhodocyclales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
k59_197579_1	1537917.JU82_04630	2.17e-49	161.0	COG0712@1|root,COG0712@2|Bacteria,1RFPY@1224|Proteobacteria,42SKR@68525|delta/epsilon subdivisions,2YPHX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
k59_197579_2	709032.Sulku_0757	4.05e-242	673.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,42MVX@68525|delta/epsilon subdivisions,2YMSF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	iIT341.HP1134	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_785212_1	709032.Sulku_2595	4.64e-167	469.0	COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,42MX4@68525|delta/epsilon subdivisions,2YRKU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COG0714 MoxR-like	-	-	-	ko:K04748	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	AAA_5,CbbQ_C
k59_785212_2	1249480.B649_06250	4.36e-182	520.0	COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,42P8Y@68525|delta/epsilon subdivisions,2YRE9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG4548 Nitric oxide reductase activation protein	-	-	-	ko:K02448	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	VWA
k59_1260117_1	159087.Daro_2873	3.57e-125	366.0	COG2070@1|root,COG2070@2|Bacteria,1N52W@1224|Proteobacteria,2VJ45@28216|Betaproteobacteria,2KVWV@206389|Rhodocyclales	206389|Rhodocyclales	S	2-nitropropane dioxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
k59_611191_1	887062.HGR_00085	1.48e-42	140.0	COG2938@1|root,COG2938@2|Bacteria,1N2AS@1224|Proteobacteria,2VVYR@28216|Betaproteobacteria,4AFH3@80864|Comamonadaceae	28216|Betaproteobacteria	S	Flavinator of succinate dehydrogenase	-	-	-	ko:K09159	-	-	-	-	ko00000,ko02048	-	-	-	Sdh5
k59_611191_2	94624.Bpet1823	1.28e-42	144.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,2VIKC@28216|Betaproteobacteria,3T2B6@506|Alcaligenaceae	28216|Betaproteobacteria	C	SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556	sdhB	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_17,Fer4_8
k59_785216_1	159087.Daro_1750	8.9e-98	305.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,2VHTX@28216|Betaproteobacteria,2KV13@206389|Rhodocyclales	206389|Rhodocyclales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_1783094_1	709032.Sulku_0119	1.11e-24	100.0	COG0739@1|root,COG0739@2|Bacteria,1MY2X@1224|Proteobacteria,42U06@68525|delta/epsilon subdivisions,2YP2U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_1610166_1	1249480.B649_04245	8.5e-93	290.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,42MP3@68525|delta/epsilon subdivisions,2YMP3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
k59_435832_1	1274374.CBLK010000072_gene1032	3.51e-13	68.2	COG0451@1|root,COG0451@2|Bacteria,1TQW7@1239|Firmicutes,4HTKC@91061|Bacilli,26V3I@186822|Paenibacillaceae	91061|Bacilli	GM	CDP-glucose 4,6-dehydratase	ddhB	-	4.2.1.45	ko:K01709	ko00520,map00520	-	R02426	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
k59_435832_2	395494.Galf_2850	9.93e-82	247.0	COG1208@1|root,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,2VIQG@28216|Betaproteobacteria,44W79@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Nucleotidyl transferase	rfbF	-	2.7.7.33,2.7.7.71	ko:K00978,ko:K15669	ko00500,ko00520,ko00540,ko01100,map00500,map00520,map00540,map01100	-	R00956,R09772	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
k59_1610196_1	1249480.B649_04995	5.62e-129	374.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2YMY9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_1493260_1	159087.Daro_0049	5.73e-79	247.0	COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,2VHTW@28216|Betaproteobacteria,2KUCA@206389|Rhodocyclales	206389|Rhodocyclales	EGP	drug resistance transporter	-	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1
k59_677262_1	1537917.JU82_06840	5.79e-166	484.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,42MM9@68525|delta/epsilon subdivisions,2YMH2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
k59_905932_2	1123326.JFBL01000023_gene2558	3.83e-23	100.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,42MEM@68525|delta/epsilon subdivisions,2YMWQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	kefB	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
k59_615754_1	298386.PBPRB1754	3.19e-55	199.0	COG1361@1|root,COG2911@1|root,COG2931@1|root,COG1361@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria	1224|Proteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	3.4.24.40	ko:K01406,ko:K20276	ko01503,ko02024,map01503,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Big_3_2,HemolysinCabind,VCBS,VWA_2
k59_1851060_1	397945.Aave_4273	6.39e-54	178.0	COG0639@1|root,COG0639@2|Bacteria,1MUV1@1224|Proteobacteria,2VM0A@28216|Betaproteobacteria,4A9UQ@80864|Comamonadaceae	28216|Betaproteobacteria	T	PFAM metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
k59_1557487_1	562983.HMPREF0433_00325	1.05e-35	138.0	COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4H9Z5@91061|Bacilli,3WERV@539002|Bacillales incertae sedis	91061|Bacilli	C	E3 component of the branched-chain alpha-keto acid dehydrogenase complex	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
k59_1493313_1	1132855.KB913035_gene319	5.17e-37	132.0	2EQAV@1|root,33HX0@2|Bacteria,1NPHM@1224|Proteobacteria,2WHZ1@28216|Betaproteobacteria,2KNVV@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Domain of unknown function (DUF4124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124
k59_1199130_1	1132855.KB913035_gene931	1.46e-78	250.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,2VHHA@28216|Betaproteobacteria,2KMFA@206350|Nitrosomonadales	206350|Nitrosomonadales	L	May be involved in recombinational repair of damaged DNA	-	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
k59_1376151_2	1249480.B649_03515	1.11e-77	238.0	COG1792@1|root,COG1792@2|Bacteria,1QB26@1224|Proteobacteria,42MF4@68525|delta/epsilon subdivisions,2YNT9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Rod shape-determining protein MreC	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
k59_1439978_1	1537917.JU82_02465	2.42e-113	337.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,42MAI@68525|delta/epsilon subdivisions,2YMCW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	iIT341.HP0476	tRNA-synt_1c
k59_1264448_1	387093.SUN_0761	1.78e-29	114.0	COG0803@1|root,COG0803@2|Bacteria,1MVW9@1224|Proteobacteria,42MBX@68525|delta/epsilon subdivisions,2YNF1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0803 ABC-type metal ion transport system, periplasmic component surface adhesin	-	-	-	ko:K02077	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
k59_1264448_2	563040.Saut_0065	3.23e-22	93.2	COG1108@1|root,COG1108@2|Bacteria,1PZT7@1224|Proteobacteria,42R3J@68525|delta/epsilon subdivisions,2YP3H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	ABC 3 transport family	-	-	-	ko:K02075	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC-3
k59_1728073_1	709032.Sulku_1005	4.7e-25	100.0	COG0694@1|root,COG0822@1|root,COG0694@2|Bacteria,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,42MT6@68525|delta/epsilon subdivisions,2YMXY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CO	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins	-	-	-	ko:K13819	-	-	-	-	ko00000	-	-	-	Fer2_BFD,NifU,NifU_N
k59_1439994_1	1537917.JU82_08285	1.31e-93	282.0	COG2956@1|root,COG2956@2|Bacteria,1QUIS@1224|Proteobacteria,42M7G@68525|delta/epsilon subdivisions,2YMKN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_7,TPR_8
k59_1786430_2	1537917.JU82_10935	4.26e-95	294.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2YN0B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
k59_1786432_1	709032.Sulku_1186	1.96e-107	330.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,42N4X@68525|delta/epsilon subdivisions,2YMTD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Belongs to the FtsK SpoIIIE SftA family	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
k59_967982_1	1249480.B649_01880	1.31e-98	301.0	COG2433@1|root,COG2433@2|Bacteria,1QW3W@1224|Proteobacteria,42RB0@68525|delta/epsilon subdivisions,2YNE9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Pfam Transposase IS66	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
k59_260521_2	1121035.AUCH01000001_gene1823	3.05e-33	128.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,2VIB1@28216|Betaproteobacteria,2KUQZ@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	ko:K00372	ko00910,ko01120,map00910,map01120	M00531	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_1610294_2	1537917.JU82_03405	7.34e-116	339.0	COG0242@1|root,COG0242@2|Bacteria,1QNIH@1224|Proteobacteria,42TAD@68525|delta/epsilon subdivisions,2YPKH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	COG0242 N-formylmethionyl-tRNA deformylase	-	-	-	-	-	-	-	-	-	-	-	-	Pep_deformylase
k59_1145410_1	547144.HydHO_0787	7.82e-14	75.5	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	czcC	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
k59_677403_2	640081.Dsui_2195	1.49e-07	52.8	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,2VING@28216|Betaproteobacteria,2KU9B@206389|Rhodocyclales	206389|Rhodocyclales	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
k59_260541_1	525898.Sdel_0979	1.39e-51	181.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YM96@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	cmeF	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_260541_2	1249480.B649_05755	3.19e-12	65.1	COG0845@1|root,COG0845@2|Bacteria,1QE6S@1224|Proteobacteria,42QGG@68525|delta/epsilon subdivisions,2YNSD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	cmeE	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_1786464_1	709032.Sulku_1901	2.92e-99	292.0	COG4508@1|root,COG4508@2|Bacteria,1RAX1@1224|Proteobacteria,42MG5@68525|delta/epsilon subdivisions,2YN7I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM dUTPase	dut	-	-	-	-	-	-	-	-	-	-	-	dUTPase_2
k59_724039_1	1304883.KI912532_gene1505	6.91e-47	151.0	COG2331@1|root,COG2331@2|Bacteria,1N6Q9@1224|Proteobacteria,2VTX5@28216|Betaproteobacteria,2KXAG@206389|Rhodocyclales	206389|Rhodocyclales	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
k59_724039_2	159087.Daro_0635	4.93e-74	226.0	COG2928@1|root,COG2928@2|Bacteria,1MWT5@1224|Proteobacteria,2VH65@28216|Betaproteobacteria,2KV5C@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
k59_146740_1	580332.Slit_2468	1.23e-34	123.0	COG0671@1|root,COG0671@2|Bacteria,1RJ1T@1224|Proteobacteria,2VTYD@28216|Betaproteobacteria	28216|Betaproteobacteria	I	PFAM phosphoesterase, PA-phosphatase related	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
k59_146740_2	159087.Daro_3544	8.04e-09	54.3	COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,2VU5Y@28216|Betaproteobacteria,2KWKX@206389|Rhodocyclales	206389|Rhodocyclales	M	Recycling of diacylglycerol produced during the turnover of membrane phospholipid	-	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
k59_615936_1	261292.Nit79A3_2186	4.16e-08	53.1	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,2VHT5@28216|Betaproteobacteria,372KE@32003|Nitrosomonadales	28216|Betaproteobacteria	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
k59_615936_2	640512.BC1003_1401	5.29e-49	165.0	COG1512@1|root,COG1512@2|Bacteria,1PB41@1224|Proteobacteria,2VMNV@28216|Betaproteobacteria,1K55Q@119060|Burkholderiaceae	28216|Betaproteobacteria	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
k59_560563_2	326298.Suden_2053	1.66e-18	85.1	COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,42NZ4@68525|delta/epsilon subdivisions,2YNNY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	COG2067 Long-chain fatty acid transport protein	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k59_906090_1	1276756.AUEX01000004_gene2488	1.32e-76	240.0	COG0438@1|root,COG0438@2|Bacteria,1MWVX@1224|Proteobacteria,2VV1W@28216|Betaproteobacteria,4AJ0Y@80864|Comamonadaceae	28216|Betaproteobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
k59_1376252_2	1537917.JU82_08040	1.17e-15	75.9	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2YMW4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_1031322_1	709032.Sulku_1861	1.53e-124	372.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,42MUY@68525|delta/epsilon subdivisions,2YMZF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	PFAM peptidase M3A and M3B thimet oligopeptidase F	prlC	-	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
k59_436070_1	709032.Sulku_0219	2.27e-126	379.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1RGCV@1224|Proteobacteria,43CEF@68525|delta/epsilon subdivisions,2YTHA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_1728206_2	1249480.B649_07190	3.98e-45	155.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	CarbopepD_reg_2,TonB_2,TonB_C
k59_23986_1	1304883.KI912532_gene1654	7.22e-18	77.4	COG3113@1|root,COG3113@2|Bacteria,1PJKD@1224|Proteobacteria,2VW6E@28216|Betaproteobacteria,2KXIR@206389|Rhodocyclales	206389|Rhodocyclales	S	STAS domain	-	-	-	ko:K07122	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	STAS_2
k59_23986_2	1304883.KI912532_gene1653	9.22e-106	310.0	COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,2VR85@28216|Betaproteobacteria,2KW7C@206389|Rhodocyclales	206389|Rhodocyclales	Q	ABC-type transport system involved in resistance to organic solvents, auxiliary component	-	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
k59_23986_3	159087.Daro_3399	1.16e-11	62.8	COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,2VQ97@28216|Betaproteobacteria,2KW45@206389|Rhodocyclales	206389|Rhodocyclales	M	VacJ family lipoprotein	vacJ	-	-	ko:K04754	-	-	-	-	ko00000	-	-	-	MlaA
k59_1728236_1	1249480.B649_09790	1.04e-86	262.0	COG0642@1|root,COG0642@2|Bacteria,1QZ1Z@1224|Proteobacteria,42SN7@68525|delta/epsilon subdivisions,2YPK7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
k59_1728236_2	1249480.B649_09785	1.37e-35	124.0	COG0811@1|root,COG0811@2|Bacteria,1RK2P@1224|Proteobacteria,42TPV@68525|delta/epsilon subdivisions,2YPGE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Biopolymer transporter ExbB	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k59_1264643_1	159087.Daro_3872	2.29e-102	323.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
k59_560643_1	1537917.JU82_04695	1.14e-130	377.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,42MKH@68525|delta/epsilon subdivisions,2YMWK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	malonyl coa-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
k59_1376312_1	1121428.DESHY_20176___1	4.7e-97	304.0	COG1148@1|root,COG1908@1|root,COG1148@2|Bacteria,COG1908@2|Bacteria,1UT78@1239|Firmicutes,24A6H@186801|Clostridia,26171@186807|Peptococcaceae	186801|Clostridia	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	ko:K16886	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_9,FlpD,Pyr_redox_2
k59_436145_1	1249480.B649_08755	2.81e-162	469.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2YMIX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	ctsE	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
k59_1376332_1	709032.Sulku_1076	4.18e-122	356.0	COG3228@1|root,COG3228@2|Bacteria,1RAHF@1224|Proteobacteria,42QKQ@68525|delta/epsilon subdivisions,2YMYQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the MtfA family	-	-	-	ko:K09933	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_M90
k59_1313652_1	211586.SO_4150	3.61e-40	146.0	COG0659@1|root,COG0659@2|Bacteria,1MX1U@1224|Proteobacteria,1S567@1236|Gammaproteobacteria,2Q8RW@267890|Shewanellaceae	1236|Gammaproteobacteria	P	PFAM Xanthine uracil vitamin C permease	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	MFS_MOT1
k59_677629_1	2340.JV46_02990	5.17e-45	165.0	COG4262@1|root,COG4262@2|Bacteria,1QUPY@1224|Proteobacteria,1RMJV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
k59_789948_1	709032.Sulku_1029	1.42e-81	252.0	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,42MJ9@68525|delta/epsilon subdivisions,2YNG4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
k59_260697_1	1304883.KI912532_gene1185	2.73e-147	431.0	COG0438@1|root,COG0438@2|Bacteria,1MVEG@1224|Proteobacteria,2VIK3@28216|Betaproteobacteria,2KYEE@206389|Rhodocyclales	206389|Rhodocyclales	M	Domain of unknown function (DUF3492)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3492
k59_260697_2	266264.Rmet_4161	1.63e-119	357.0	COG4267@1|root,COG4267@2|Bacteria,1MUQN@1224|Proteobacteria,2VMET@28216|Betaproteobacteria,1K3XA@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Putative exopolysaccharide Exporter (EPS-E)	ragG	-	-	ko:K21012	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	PelG
k59_1440267_2	929558.SMGD1_0790	2.97e-36	127.0	COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,42T4D@68525|delta/epsilon subdivisions,2YPHE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Low molecular weight phosphotyrosine protein phosphatase	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
k59_968243_1	709032.Sulku_1184	5.66e-103	313.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2YNK5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DEAD box helicase family	dbpA	-	3.6.4.13	ko:K05591	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DEAD,DbpA,Helicase_C
k59_436187_1	1537917.JU82_00255	2.39e-108	325.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,42ND6@68525|delta/epsilon subdivisions,2YN5S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
k59_906210_2	159087.Daro_1404	3.35e-20	90.1	COG2864@1|root,COG2864@2|Bacteria,1NJEJ@1224|Proteobacteria,2VKG8@28216|Betaproteobacteria,2KY24@206389|Rhodocyclales	206389|Rhodocyclales	P	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1518368_1	1121035.AUCH01000003_gene1258	1.29e-119	345.0	COG1584@1|root,COG1584@2|Bacteria,1N3HP@1224|Proteobacteria,2VPSY@28216|Betaproteobacteria,2KVI0@206389|Rhodocyclales	206389|Rhodocyclales	S	GPR1/FUN34/yaaH family	-	-	-	ko:K07034	-	-	-	-	ko00000	-	-	-	Grp1_Fun34_YaaH
k59_1518368_2	159087.Daro_2852	6.45e-08	52.8	COG3409@1|root,COG3409@2|Bacteria,1NEG1@1224|Proteobacteria,2VV5Y@28216|Betaproteobacteria,2KXXE@206389|Rhodocyclales	206389|Rhodocyclales	M	Glycosyl hydrolase family 46	-	-	3.2.1.132	ko:K01233	ko00520,ko01100,map00520,map01100	-	R02833	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_46,PG_binding_1
k59_1466564_1	1158165.KB898872_gene1135	2.18e-30	125.0	COG0642@1|root,COG2202@1|root,COG2203@1|root,COG3829@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,1NRP8@1224|Proteobacteria,1RWY1@1236|Gammaproteobacteria,1X06S@135613|Chromatiales	135613|Chromatiales	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,PAS_9
k59_172087_1	395494.Galf_0449	5.61e-193	555.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,2VKSY@28216|Betaproteobacteria,44V4I@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
k59_1693748_1	1172190.M947_10630	1.91e-15	72.0	COG4786@1|root,COG4786@2|Bacteria,1NC8Z@1224|Proteobacteria,42XCU@68525|delta/epsilon subdivisions,2YQV6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Flagellar hook protein flgE	-	-	-	-	-	-	-	-	-	-	-	-	Flg_bb_rod,Flg_bbr_C
k59_1693748_2	1249480.B649_05600	5.71e-36	133.0	COG0791@1|root,COG0791@2|Bacteria,1R45H@1224|Proteobacteria,42NS0@68525|delta/epsilon subdivisions,2YN06@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,N_NLPC_P60,Peptidase_M15_4,SH3_6,SH3_7
k59_996913_1	1089447.RHAA1_07928	1.92e-08	57.8	COG0042@1|root,COG0042@2|Bacteria,1MUY1@1224|Proteobacteria,1RN28@1236|Gammaproteobacteria,1Y7C1@135625|Pasteurellales	135625|Pasteurellales	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs	dusA	-	-	ko:K05539	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
k59_996913_2	743720.Psefu_0929	6.94e-35	127.0	COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,1RPU9@1236|Gammaproteobacteria,1YW94@136845|Pseudomonas putida group	1236|Gammaproteobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
k59_285653_1	1249480.B649_09090	6.1e-106	313.0	28M05@1|root,2ZAF9@2|Bacteria,1MY5U@1224|Proteobacteria,42MJP@68525|delta/epsilon subdivisions,2YMVI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	General glycosylation pathway protein	pglG	-	-	-	-	-	-	-	-	-	-	-	dCache_1
k59_934788_1	709032.Sulku_0630	5.85e-10	55.1	2EGFD@1|root,33A7D@2|Bacteria,1NH03@1224|Proteobacteria,42WZI@68525|delta/epsilon subdivisions,2YSM9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF1656)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1656
k59_934788_2	709032.Sulku_0629	3.69e-49	174.0	COG1289@1|root,COG1289@2|Bacteria,1MX9H@1224|Proteobacteria,43F33@68525|delta/epsilon subdivisions,2YRBI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Aromatic acid exporter family member 1	-	-	-	-	-	-	-	-	-	-	-	-	FUSC
k59_1340904_1	555778.Hneap_1795	5.24e-92	277.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,1RPV9@1236|Gammaproteobacteria,1WXSR@135613|Chromatiales	135613|Chromatiales	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
k59_1340904_2	555778.Hneap_1796	4.32e-09	57.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,1RQXJ@1236|Gammaproteobacteria,1WWUX@135613|Chromatiales	135613|Chromatiales	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
k59_1693768_1	1165841.SULAR_07645	1.56e-121	359.0	COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1MY1V@1224|Proteobacteria,42P2P@68525|delta/epsilon subdivisions	1224|Proteobacteria	G	phosphotransferase system, EIIB	nagE	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006950,GO:0006974,GO:0008150,GO:0008643,GO:0009401,GO:0009987,GO:0015144,GO:0015764,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0033554,GO:0034219,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071702,GO:0090563,GO:0090586,GO:1901264	2.7.1.193	ko:K02802,ko:K02803,ko:K02804	ko00520,ko02060,map00520,map02060	M00267	R05199	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7	-	iECP_1309.ECP_0691	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
k59_1108688_1	1165841.SULAR_08719	2.29e-149	431.0	COG0045@1|root,COG0045@2|Bacteria,1PYM0@1224|Proteobacteria,42YXJ@68525|delta/epsilon subdivisions,2YR3Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	ATP citrate lyase citrate-binding	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_2,Citrate_bind
k59_1754626_1	709032.Sulku_1307	2.71e-70	231.0	COG2199@1|root,COG2199@2|Bacteria,1RGCV@1224|Proteobacteria,42YPK@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,CHASE8,EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_8,PAS_9
k59_1754630_1	458817.Shal_3918	1.69e-12	70.5	COG1587@1|root,COG1587@2|Bacteria,1MWZD@1224|Proteobacteria,1RM9K@1236|Gammaproteobacteria,2QAPQ@267890|Shewanellaceae	1236|Gammaproteobacteria	H	PFAM Uroporphyrinogen III synthase HEM4	hemD	GO:0003674,GO:0003824,GO:0004852,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	iJN746.PP_0187,iSBO_1134.SBO_3815	HEM4
k59_870366_1	1165841.SULAR_00245	1.37e-86	259.0	COG0745@1|root,COG0745@2|Bacteria,1Q4KJ@1224|Proteobacteria,42ZD8@68525|delta/epsilon subdivisions,2YRA5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
k59_523094_1	717773.Thicy_0253	1.56e-42	154.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,45ZWV@72273|Thiotrichales	72273|Thiotrichales	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_285748_1	709032.Sulku_0949	5.3e-78	251.0	COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42PMU@68525|delta/epsilon subdivisions,2YNHE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4
k59_1400890_1	709032.Sulku_0225	9.08e-135	388.0	COG1242@1|root,COG1242@2|Bacteria,1MUYF@1224|Proteobacteria,42PX9@68525|delta/epsilon subdivisions,2YN2U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Radical SAM protein	-	-	-	ko:K07139	-	-	-	-	ko00000	-	-	-	Radical_SAM,Radical_SAM_C
k59_1108754_1	991905.SL003B_1307	2.42e-115	363.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2TQTG@28211|Alphaproteobacteria,4BTG1@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	H	Vitamin B12 dependent methionine synthase, activation domain	metH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
k59_460657_1	159087.Daro_2465	2.94e-84	273.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,2VHQ6@28216|Betaproteobacteria,2KUZT@206389|Rhodocyclales	206389|Rhodocyclales	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
k59_934940_1	159087.Daro_0956	2.8e-106	314.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,2VHD0@28216|Betaproteobacteria,2KUKP@206389|Rhodocyclales	206389|Rhodocyclales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
k59_934942_1	1537917.JU82_02040	9.96e-111	347.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42M0A@68525|delta/epsilon subdivisions,2YNJ1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	cznA	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
k59_46962_1	709032.Sulku_0525	6.59e-55	178.0	COG0745@1|root,COG0745@2|Bacteria,1R9AZ@1224|Proteobacteria,42NYS@68525|delta/epsilon subdivisions,2YNW2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	response regulator	dccR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_46962_2	709032.Sulku_0524	1.64e-14	72.8	COG5002@1|root,COG5002@2|Bacteria,1QZ29@1224|Proteobacteria,43CEG@68525|delta/epsilon subdivisions,2YTC2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_1400922_2	387093.SUN_2242	6.05e-18	83.2	COG0642@1|root,COG0642@2|Bacteria,1RGPU@1224|Proteobacteria,42RPY@68525|delta/epsilon subdivisions,2YPD9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG0642 Signal transduction histidine kinase	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_1113825_1	387093.SUN_0572	1.36e-37	134.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,42KZJ@68525|delta/epsilon subdivisions,2YMR0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
k59_1113825_2	387093.SUN_0573	4.51e-74	228.0	COG1951@1|root,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,42MC7@68525|delta/epsilon subdivisions,2YN8Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Fumarate hydratase	ttdA	-	4.2.1.2	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
k59_1406396_1	1121035.AUCH01000002_gene1478	2.95e-50	175.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,2VIBW@28216|Betaproteobacteria,2KVF9@206389|Rhodocyclales	206389|Rhodocyclales	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
k59_1113829_1	1384054.N790_07825	4.6e-14	68.9	COG2391@1|root,COG2391@2|Bacteria,1RIWE@1224|Proteobacteria,1S93K@1236|Gammaproteobacteria,1X75A@135614|Xanthomonadales	135614|Xanthomonadales	S	Sulphur transport	-	-	-	-	-	-	-	-	-	-	-	-	Sulf_transp
k59_1113829_2	312153.Pnuc_0788	8.51e-66	206.0	COG2391@1|root,COG2391@2|Bacteria,1N3PQ@1224|Proteobacteria,2VXAQ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
k59_343928_1	1165841.SULAR_09644	6.85e-58	189.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,42MM1@68525|delta/epsilon subdivisions,2YN3A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	8-amino-7-oxononanoate synthase	bioF	-	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_343928_2	1165841.SULAR_09649	1.12e-79	240.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,42SR7@68525|delta/epsilon subdivisions,2YP8T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	nucleotide-binding protein implicated in inhibition of septum formation	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
k59_465807_1	1537917.JU82_02540	1.41e-168	480.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,42M0V@68525|delta/epsilon subdivisions,2YMAY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Glycolate oxidase subunit	glcD	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
k59_750628_1	1123517.JOMR01000001_gene1977	1.65e-59	192.0	COG0106@1|root,COG0107@1|root,COG0106@2|Bacteria,COG0107@2|Bacteria,1MW6S@1224|Proteobacteria,1RN3M@1236|Gammaproteobacteria,45ZZE@72273|Thiotrichales	72273|Thiotrichales	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
k59_1113851_1	387093.SUN_1013	1.1e-102	313.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42NK1@68525|delta/epsilon subdivisions,2YMHN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the AAA ATPase family	ftsH1	-	-	-	-	-	-	-	-	-	-	-	AAA,Peptidase_M41
k59_1406435_1	395494.Galf_1859	3.03e-82	256.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VIF8@28216|Betaproteobacteria,44VHW@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Thiolase, C-terminal domain	fadA	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
k59_1229203_2	1163617.SCD_n00967	2.54e-08	53.9	COG0492@1|root,COG1145@1|root,COG0492@2|Bacteria,COG1145@2|Bacteria	2|Bacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	trxB_2	-	1.18.1.2,1.19.1.1,1.8.1.9	ko:K00384,ko:K21567	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Fer4,Fer4_10,Pyr_redox_3
k59_875339_1	709032.Sulku_0065	2.34e-58	203.0	COG4581@1|root,COG4581@2|Bacteria,1MVD6@1224|Proteobacteria,42PR3@68525|delta/epsilon subdivisions,2YN2Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Mitochondrial degradasome RNA helicase subunit C terminal	-	-	3.6.4.13	ko:K17675	-	-	-	-	ko00000,ko01000,ko03029	-	-	-	Helicase_C,SUV3_C
k59_465862_1	709032.Sulku_1889	5.52e-131	381.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,42M7H@68525|delta/epsilon subdivisions,2YMPK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
k59_405065_1	1249480.B649_11555	7.56e-33	116.0	2AJ5V@1|root,319QG@2|Bacteria,1Q3K7@1224|Proteobacteria,42XFR@68525|delta/epsilon subdivisions,2YQU7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1229242_2	1249480.B649_08135	2.44e-98	290.0	COG0388@1|root,COG0388@2|Bacteria,1QBMA@1224|Proteobacteria,42PD8@68525|delta/epsilon subdivisions,2YMD1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	hydrolase	-	-	3.5.5.1	ko:K01501	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
k59_1642787_1	1249480.B649_00230	5.31e-13	67.8	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,42M0U@68525|delta/epsilon subdivisions,2YNJV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	mechanosensitive ion channel	mscS	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
k59_1642787_3	709032.Sulku_0063	5.53e-47	154.0	COG1547@1|root,COG1547@2|Bacteria,1PD94@1224|Proteobacteria,42WUE@68525|delta/epsilon subdivisions,2YQXY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function (DUF309)	-	-	-	-	-	-	-	-	-	-	-	-	DUF309
k59_1642787_4	709032.Sulku_0064	7.73e-56	175.0	COG0607@1|root,COG0607@2|Bacteria,1Q1NN@1224|Proteobacteria,42U2F@68525|delta/epsilon subdivisions,2YQ1E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1642787_5	1249480.B649_00210	7.44e-132	403.0	COG4581@1|root,COG4581@2|Bacteria,1MVD6@1224|Proteobacteria,42PR3@68525|delta/epsilon subdivisions,2YN2Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Mitochondrial degradasome RNA helicase subunit C terminal	-	-	3.6.4.13	ko:K17675	-	-	-	-	ko00000,ko01000,ko03029	-	-	-	Helicase_C,SUV3_C
k59_1699139_1	1042163.BRLA_c025650	2.88e-45	166.0	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,4HAHU@91061|Bacilli,26Q93@186822|Paenibacillaceae	91061|Bacilli	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	ko:K15662	ko01054,map01054	-	-	-	ko00000,ko00001,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_1346059_1	1249480.B649_05890	2.22e-44	150.0	COG1451@1|root,COG1451@2|Bacteria,1MXZU@1224|Proteobacteria,42V1Y@68525|delta/epsilon subdivisions,2YQDY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	hmm pf01863	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
k59_1346059_2	709032.Sulku_1418	2.11e-75	229.0	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,42MKZ@68525|delta/epsilon subdivisions,2YMGA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
k59_465938_1	1537917.JU82_00095	1.56e-126	368.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,42MNJ@68525|delta/epsilon subdivisions,2YMDC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
k59_1642830_1	159087.Daro_3924	5.36e-61	192.0	COG2518@1|root,COG2518@2|Bacteria,1RD6S@1224|Proteobacteria,2VJX3@28216|Betaproteobacteria,2KUMH@206389|Rhodocyclales	206389|Rhodocyclales	O	protein-L-isoaspartate(D-aspartate) O-methyltransferase	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
k59_1642830_2	159087.Daro_3923	9.39e-33	119.0	COG1309@1|root,COG1309@2|Bacteria,1MVQV@1224|Proteobacteria,2VK6A@28216|Betaproteobacteria,2KW36@206389|Rhodocyclales	206389|Rhodocyclales	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
k59_1642836_1	1123393.KB891332_gene2832	2.54e-32	119.0	COG2068@1|root,COG2068@2|Bacteria,1MW0X@1224|Proteobacteria,2VSIN@28216|Betaproteobacteria,1KRTP@119069|Hydrogenophilales	119069|Hydrogenophilales	S	MobA-like NTP transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3
k59_1642836_2	572477.Alvin_1313	2.73e-11	62.8	2E8DE@1|root,332RW@2|Bacteria,1N96Q@1224|Proteobacteria,1SCDT@1236|Gammaproteobacteria,1X2MS@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1113981_1	1500893.JQNB01000001_gene2563	7.13e-14	72.8	COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,1RMTU@1236|Gammaproteobacteria,1X3UX@135614|Xanthomonadales	135614|Xanthomonadales	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
k59_1346080_1	709032.Sulku_2335	4.58e-61	196.0	COG3907@1|root,COG3907@2|Bacteria,1MY7B@1224|Proteobacteria,42RAC@68525|delta/epsilon subdivisions,2YQ1I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COGs COG3907 PAP2 (acid phosphatase) superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
k59_1642852_1	159087.Daro_3097	6.5e-110	335.0	COG0840@1|root,COG0840@2|Bacteria,1NJXF@1224|Proteobacteria,2VM8I@28216|Betaproteobacteria,2KV4E@206389|Rhodocyclales	206389|Rhodocyclales	NT	Methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
k59_1814270_1	1504672.669783168	7.52e-36	131.0	COG0535@1|root,COG0535@2|Bacteria,1MU07@1224|Proteobacteria,2VKSA@28216|Betaproteobacteria,4AANE@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3641)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3641,Radical_SAM
k59_1814270_2	85643.Tmz1t_1330	4.96e-26	105.0	COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,2VJ59@28216|Betaproteobacteria,2KVX5@206389|Rhodocyclales	206389|Rhodocyclales	E	Bacterial extracellular solute-binding protein	-	-	-	ko:K02055	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	SBP_bac_8
k59_1346096_1	709032.Sulku_1514	3.35e-101	298.0	28I9W@1|root,2Z8CH@2|Bacteria,1QCN6@1224|Proteobacteria,42Z77@68525|delta/epsilon subdivisions,2YRAX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	SIR2-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
k59_1759861_1	1046714.AMRX01000001_gene1837	4.19e-117	342.0	COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,1RMM8@1236|Gammaproteobacteria,464YS@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX	hemF	GO:0003674,GO:0003824,GO:0004109,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016634,GO:0018130,GO:0019438,GO:0030145,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0046983,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b2436,iBWG_1329.BWG_2198,iECDH10B_1368.ECDH10B_2601,iECDH1ME8569_1439.ECDH1ME8569_2370,iETEC_1333.ETEC_2549,iEcDH1_1363.EcDH1_1225,iEcHS_1320.EcHS_A2573,iEcolC_1368.EcolC_1243,iJO1366.b2436,iJR904.b2436,iY75_1357.Y75_RS12760	Coprogen_oxidas
k59_528189_1	743720.Psefu_2689	1.03e-34	137.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1YWRT@136845|Pseudomonas putida group	1236|Gammaproteobacteria	T	Histidine kinase	sagS	-	2.7.13.3	ko:K20973	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Response_reg
k59_1699232_1	709032.Sulku_1495	5.51e-42	145.0	COG2199@1|root,COG2199@2|Bacteria,1Q2N5@1224|Proteobacteria,42VZ7@68525|delta/epsilon subdivisions,2YQIC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG2199 FOG GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_528255_1	1123487.KB892863_gene1862	4.2e-28	113.0	COG0038@1|root,COG0038@2|Bacteria,1MV4K@1224|Proteobacteria,2VHFE@28216|Betaproteobacteria,2KVID@206389|Rhodocyclales	206389|Rhodocyclales	P	Voltage gated chloride channel	-	-	-	-	-	-	-	-	-	-	-	-	Voltage_CLC
k59_528255_2	159087.Daro_3911	2.48e-73	228.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,2VHSA@28216|Betaproteobacteria,2KV15@206389|Rhodocyclales	206389|Rhodocyclales	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
k59_290442_1	1249480.B649_09015	3.59e-34	120.0	2AK8C@1|root,31AYM@2|Bacteria,1Q6J3@1224|Proteobacteria,43398@68525|delta/epsilon subdivisions,2YSRM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_290442_2	1249480.B649_10455	3.12e-48	156.0	28QM5@1|root,2ZD2X@2|Bacteria,1P3YE@1224|Proteobacteria,42WN9@68525|delta/epsilon subdivisions,2YQE1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_290442_3	1537917.JU82_03475	1.19e-50	162.0	COG3323@1|root,COG3323@2|Bacteria,1MZF5@1224|Proteobacteria,42W00@68525|delta/epsilon subdivisions,2YS8D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_290442_4	709032.Sulku_1882	3.13e-146	419.0	COG1090@1|root,COG1090@2|Bacteria,1MUB4@1224|Proteobacteria,42QUU@68525|delta/epsilon subdivisions,2YNXM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Epimerase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
k59_528266_2	298386.PBPRA3277	0.000267	47.0	COG4968@1|root,COG4968@2|Bacteria,1R4X4@1224|Proteobacteria,1T22U@1236|Gammaproteobacteria,1Y2EH@135623|Vibrionales	135623|Vibrionales	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K10925	ko05111,map05111	-	-	-	ko00000,ko00001,ko02044	-	-	-	N_methyl
k59_344201_2	1537917.JU82_05230	3.18e-56	192.0	COG1042@1|root,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,42KZW@68525|delta/epsilon subdivisions,2YN6G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
k59_1699308_1	709032.Sulku_2190	4.37e-130	382.0	COG1866@1|root,COG1866@2|Bacteria,1MWXN@1224|Proteobacteria,42N5Y@68525|delta/epsilon subdivisions,2YN1U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
k59_290453_1	1249480.B649_05270	3.43e-126	385.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2YNQF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0474 Cation transport ATPase	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3,Na_H_Exchanger
k59_1759946_2	1123518.ARWI01000001_gene1345	1.07e-35	134.0	COG0715@1|root,COG0715@2|Bacteria,1NV0U@1224|Proteobacteria,1SNZC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	-
k59_344222_1	387093.SUN_1076	9.74e-91	272.0	COG0847@1|root,COG0847@2|Bacteria,1PDD1@1224|Proteobacteria,42MUX@68525|delta/epsilon subdivisions,2YNB6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG0847 DNA polymerase III epsilon subunit and related 3'-5'	-	-	2.7.7.7	ko:K02342,ko:K10857	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_1114111_3	1249480.B649_00530	3.78e-44	155.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,42MIH@68525|delta/epsilon subdivisions,2YR84@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing EAL and modified HD-GYP domains	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
k59_1523069_1	1537917.JU82_11830	5.01e-83	258.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,42MPS@68525|delta/epsilon subdivisions,2YMSR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	apolipoprotein N-acyltransferase	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
k59_1699344_1	582744.Msip34_1843	1.21e-75	233.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,2VIXG@28216|Betaproteobacteria,2KKRI@206350|Nitrosomonadales	206350|Nitrosomonadales	G	PFAM Inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
k59_405273_1	709032.Sulku_1612	2.41e-51	169.0	29DMK@1|root,300JF@2|Bacteria,1Q6BD@1224|Proteobacteria,432QV@68525|delta/epsilon subdivisions,2YSKF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_939213_1	1537917.JU82_09715	2.24e-150	454.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,42MWW@68525|delta/epsilon subdivisions,2YMMH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_1248509_1	1304883.KI912532_gene46	7.25e-100	293.0	COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,2VSEQ@28216|Betaproteobacteria,2KWC2@206389|Rhodocyclales	206389|Rhodocyclales	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
k59_304883_1	349521.HCH_00794	2.02e-37	143.0	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG2202@1|root,COG5000@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG5000@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1XNGF@135619|Oceanospirillales	135619|Oceanospirillales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_9,Response_reg,dCache_1
k59_1248523_1	305700.B447_18183	5.07e-13	68.9	COG5534@1|root,COG5534@2|Bacteria,1MXQ0@1224|Proteobacteria,2VJHV@28216|Betaproteobacteria,2KZ78@206389|Rhodocyclales	206389|Rhodocyclales	L	Replication initiator protein A	-	-	-	-	-	-	-	-	-	-	-	-	RPA
k59_1248523_3	1268622.AVS7_01546	1.13e-28	108.0	COG1192@1|root,COG1192@2|Bacteria,1MWH3@1224|Proteobacteria,2VMD8@28216|Betaproteobacteria	28216|Betaproteobacteria	D	PFAM Cobyrinic acid a,c-diamide synthase	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
k59_836100_1	640081.Dsui_3490	4.19e-08	55.8	COG4966@1|root,COG4966@2|Bacteria,1RDRS@1224|Proteobacteria,2VRII@28216|Betaproteobacteria,2KX12@206389|Rhodocyclales	206389|Rhodocyclales	NU	Type IV Pilus-assembly protein W	-	-	-	ko:K02672	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl,PilW
k59_836100_2	375286.mma_3356	9.18e-11	63.9	COG4726@1|root,COG4726@2|Bacteria,1N9CE@1224|Proteobacteria,2VWPP@28216|Betaproteobacteria,47556@75682|Oxalobacteraceae	28216|Betaproteobacteria	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1186994_1	159087.Daro_2373	1.33e-14	67.8	COG0236@1|root,COG0236@2|Bacteria,1NEMA@1224|Proteobacteria,2VW0X@28216|Betaproteobacteria,2KXFD@206389|Rhodocyclales	206389|Rhodocyclales	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
k59_1186994_2	1304883.KI912532_gene2555	4.12e-70	223.0	COG0842@1|root,COG0842@2|Bacteria,1R94U@1224|Proteobacteria,2VM36@28216|Betaproteobacteria,2KW7K@206389|Rhodocyclales	206389|Rhodocyclales	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
k59_953781_1	640081.Dsui_0046	1.02e-109	335.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,2VHPQ@28216|Betaproteobacteria,2KV0N@206389|Rhodocyclales	206389|Rhodocyclales	E	Oligopeptidase	prlC	-	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
k59_1541768_1	1249480.B649_11460	1.3e-96	302.0	COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MWDY@1224|Proteobacteria,43BJD@68525|delta/epsilon subdivisions,2YNEB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	2-acylglycerophosphoethanolamine acyltransferase	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase
k59_1187002_1	709032.Sulku_1282	6.53e-39	147.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2YNMM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.6,3.6.3.8	ko:K01535,ko:K01537	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.3.2,3.A.3.3	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
k59_132161_1	583345.Mmol_1143	1.38e-38	134.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,2VJ3S@28216|Betaproteobacteria,2KMAU@206350|Nitrosomonadales	206350|Nitrosomonadales	IQ	TIGRFAM 3-oxoacyl-(acyl-carrier-protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_132161_2	1502770.JQMG01000001_gene2015	1.1e-44	145.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,2VTZH@28216|Betaproteobacteria,2KN5P@206350|Nitrosomonadales	206350|Nitrosomonadales	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
k59_132161_3	1502770.JQMG01000001_gene2016	6.75e-52	174.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,2VI6I@28216|Betaproteobacteria,2KMFU@206350|Nitrosomonadales	206350|Nitrosomonadales	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_1481458_1	1165841.SULAR_06833	6.91e-62	204.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,42NIH@68525|delta/epsilon subdivisions,2YMVT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	FP	Guanosine pentaphosphate phosphohydrolase	gppA	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
k59_1481458_2	387093.SUN_1984	3.56e-22	87.0	COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,42U8W@68525|delta/epsilon subdivisions,2YPVK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Ferredoxin	fdxB	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4
k59_13647_1	1249480.B649_03055	9.24e-29	107.0	COG0652@1|root,COG0652@2|Bacteria,1RENS@1224|Proteobacteria,42RIB@68525|delta/epsilon subdivisions,2YPAC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Pro_isomerase
k59_13647_2	1249480.B649_03060	6.2e-85	251.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,42N4Z@68525|delta/epsilon subdivisions,2YTJ1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07305,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
k59_1598059_1	1304883.KI912532_gene1971	8.39e-137	396.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,2VI86@28216|Betaproteobacteria,2KV0C@206389|Rhodocyclales	206389|Rhodocyclales	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
k59_1598059_2	999541.bgla_1g22840	1.84e-14	67.4	COG1923@1|root,COG1923@2|Bacteria,1MZM1@1224|Proteobacteria,2VTXK@28216|Betaproteobacteria,1K8J4@119060|Burkholderiaceae	28216|Betaproteobacteria	J	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
k59_248241_1	279714.FuraDRAFT_2654	7.93e-50	171.0	COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,2VJP9@28216|Betaproteobacteria,2KU4J@206351|Neisseriales	206351|Neisseriales	H	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway	bioC	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
k59_1187020_1	1042377.AFPJ01000054_gene1689	1.21e-30	109.0	COG3615@1|root,COG3615@2|Bacteria,1QVHF@1224|Proteobacteria,1T2PV@1236|Gammaproteobacteria,46D8A@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Protein of unknown function (DUF3565)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3565
k59_1187020_2	1216976.AX27061_2513	1.88e-06	49.3	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,2VHBD@28216|Betaproteobacteria,3T1QY@506|Alcaligenaceae	28216|Betaproteobacteria	O	Membrane protease subunits, stomatin prohibitin homologs	qmcA	-	-	-	-	-	-	-	-	-	-	-	Band_7,Band_7_C
k59_1303375_2	709032.Sulku_0307	2.48e-62	202.0	COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,42MRJ@68525|delta/epsilon subdivisions,2YMF2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,UPF0004
k59_1248575_1	1218076.BAYB01000002_gene483	2.59e-75	232.0	COG2995@1|root,COG2995@2|Bacteria,1RAQ9@1224|Proteobacteria,2VRNW@28216|Betaproteobacteria,1K7FQ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Paraquat-inducible protein A	-	-	-	ko:K03808	-	-	-	-	ko00000	-	-	-	PqiA
k59_248251_1	709032.Sulku_0033	1.72e-31	114.0	2DQIB@1|root,3371M@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4430)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4430
k59_248251_2	1537917.JU82_00660	1.69e-27	110.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,43BRF@68525|delta/epsilon subdivisions,2YNGV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	TonB dependent receptor	-	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
k59_1656902_1	1298593.TOL_3224	1.86e-09	58.5	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,1RN2E@1236|Gammaproteobacteria,1XHDD@135619|Oceanospirillales	135619|Oceanospirillales	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
k59_1656902_2	1048983.EL17_07475	5.83e-31	110.0	COG4628@1|root,COG4628@2|Bacteria,4NUS1@976|Bacteroidetes,47RWW@768503|Cytophagia	976|Bacteroidetes	S	conserved protein (DUF2132)	-	-	-	-	-	-	-	-	-	-	-	-	VF530
k59_1656902_3	870187.Thini_1700	3.22e-86	274.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,1RNKA@1236|Gammaproteobacteria,45ZNG@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses	nadE	-	6.3.1.5,6.3.5.1	ko:K01916,ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00189,R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
k59_69923_1	1537917.JU82_09120	5e-143	434.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,42MGK@68525|delta/epsilon subdivisions,2YMHU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_714643_1	1537917.JU82_03715	9.1e-217	605.0	COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,42MRJ@68525|delta/epsilon subdivisions,2YMF2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,UPF0004
k59_714643_2	1537917.JU82_03710	1.95e-83	255.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,42NF0@68525|delta/epsilon subdivisions,2YMRR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3
k59_1423900_1	159087.Daro_1850	2.77e-157	462.0	COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,2VH7P@28216|Betaproteobacteria,2KUX1@206389|Rhodocyclales	206389|Rhodocyclales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_1423902_1	1249480.B649_00050	4.82e-95	296.0	COG2199@1|root,COG2200@1|root,COG3620@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,COG3620@2|Bacteria,1MVJY@1224|Proteobacteria,42N7E@68525|delta/epsilon subdivisions,2YNE7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PFAM EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF
k59_1835518_1	1485544.JQKP01000004_gene524	9.46e-45	165.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,44WCD@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S)	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,PAS,PAS_4,PAS_9,SBP_bac_3,dCache_1
k59_484611_1	159087.Daro_3277	6.91e-85	259.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,2VHJF@28216|Betaproteobacteria,2KVHN@206389|Rhodocyclales	206389|Rhodocyclales	F	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
k59_1070422_2	1565314.OA34_06325	9.17e-40	146.0	COG0745@1|root,COG0745@2|Bacteria,1R0RV@1224|Proteobacteria,42SC8@68525|delta/epsilon subdivisions,2YPGT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_304997_1	387093.SUN_1933	7.57e-65	207.0	COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,42N94@68525|delta/epsilon subdivisions,2YMHM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
k59_304997_2	936155.HFELIS_08330	4.8e-12	66.2	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,42MET@68525|delta/epsilon subdivisions,2YMVE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	phosphomannomutase	glmM_1	-	5.4.2.2,5.4.2.8	ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_1835539_1	1537917.JU82_02785	4.58e-46	155.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,42N0M@68525|delta/epsilon subdivisions,2YT9X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules	xerH	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_1835539_2	1249480.B649_05035	9.86e-76	233.0	COG1521@1|root,COG1521@2|Bacteria,1PZXA@1224|Proteobacteria,42RA8@68525|delta/epsilon subdivisions,2YP14@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
k59_1835539_3	1249480.B649_05040	4.48e-81	243.0	COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,42N9N@68525|delta/epsilon subdivisions,2YN1G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
k59_15218_1	1537917.JU82_03100	9.25e-95	301.0	COG4581@1|root,COG4581@2|Bacteria,1MVD6@1224|Proteobacteria,42PR3@68525|delta/epsilon subdivisions,2YN2Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Mitochondrial degradasome RNA helicase subunit C terminal	-	-	3.6.4.13	ko:K17675	-	-	-	-	ko00000,ko01000,ko03029	-	-	-	Helicase_C,SUV3_C
k59_1250660_1	159087.Daro_4157	4.57e-62	211.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,2KUDV@206389|Rhodocyclales	206389|Rhodocyclales	P	COG0474 Cation transport ATPase	-	-	-	-	-	-	-	-	-	-	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
k59_189741_1	768671.ThimaDRAFT_1699	3.94e-66	228.0	COG0642@1|root,COG3614@1|root,COG5002@1|root,COG0642@2|Bacteria,COG3614@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1T1JE@1236|Gammaproteobacteria,1WXBB@135613|Chromatiales	135613|Chromatiales	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,PAS_8,Response_reg
k59_1717117_2	1249480.B649_01845	6.2e-31	119.0	COG2199@1|root,COG3706@2|Bacteria,1MWHH@1224|Proteobacteria,42RQ2@68525|delta/epsilon subdivisions,2YP69@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG2199 FOG GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,GGDEF
k59_1250671_1	709032.Sulku_2203	2.09e-112	325.0	COG0454@1|root,COG0456@2|Bacteria,1N3WW@1224|Proteobacteria,42XJV@68525|delta/epsilon subdivisions,2YRW0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1543917_1	1537917.JU82_10700	1.77e-113	345.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,42M45@68525|delta/epsilon subdivisions,2YNTT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	TPR_1,TPR_2,VWA_2
k59_955830_1	583345.Mmol_2315	3.78e-12	73.9	COG1538@1|root,COG1538@2|Bacteria,1R6S1@1224|Proteobacteria,2VMHP@28216|Betaproteobacteria,2KP5M@206350|Nitrosomonadales	206350|Nitrosomonadales	MU	Outer membrane efflux protein	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
k59_71328_1	1537917.JU82_01760	1.23e-92	276.0	COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,42R9F@68525|delta/epsilon subdivisions,2YNVJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
k59_306899_1	1249480.B649_03480	4.02e-72	238.0	COG1629@1|root,COG4771@2|Bacteria,1RKNG@1224|Proteobacteria	1224|Proteobacteria	P	PFAM TonB-dependent Receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_1717165_1	709032.Sulku_0068	3.28e-99	296.0	COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,42PGR@68525|delta/epsilon subdivisions,2YRIC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PFAM metal-dependent phosphohydrolase HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
k59_1599746_1	1051985.l11_06280	0.000392	41.6	COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,2VRGP@28216|Betaproteobacteria,2KR6Y@206351|Neisseriales	206351|Neisseriales	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
k59_663684_1	575589.HMPREF0018_01050	2.51e-93	285.0	COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,1RMNQ@1236|Gammaproteobacteria,3NIXJ@468|Moraxellaceae	1236|Gammaproteobacteria	E	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls	dapE	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009014,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0032153,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0046872,GO:0046914,GO:0050897,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	iECP_1309.ECP_2485	M20_dimer,Peptidase_M20
k59_486762_1	1249480.B649_01280	1.55e-130	377.0	COG0601@1|root,COG0601@2|Bacteria,1NS80@1224|Proteobacteria,42N5D@68525|delta/epsilon subdivisions,2YMX1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	ABC transporter permease	nikY	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
k59_365810_1	670487.Ocepr_2287	1.3e-15	80.9	COG0714@1|root,COG0714@2|Bacteria,1WKMC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	AAA domain (dynein-related subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
k59_838204_1	944546.ABED_1640	1.65e-70	228.0	COG1696@1|root,COG1696@2|Bacteria,1MUXN@1224|Proteobacteria,42MIR@68525|delta/epsilon subdivisions,2YN3N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Alginate O-acetylation protein	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
k59_1599767_1	1537917.JU82_11095	2.86e-31	120.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2YN6Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DNA mismatch repair MutS family	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_III,MutS_V
k59_1599767_2	944547.ABLL_2314	1.67e-13	75.1	COG0715@1|root,COG0834@1|root,COG4191@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43CE0@68525|delta/epsilon subdivisions,2YTBK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	NMT1,SBP_bac_3
k59_1426086_1	159087.Daro_1513	8.14e-67	203.0	COG0316@1|root,COG0316@2|Bacteria,1MZTE@1224|Proteobacteria,2VUJT@28216|Betaproteobacteria,2KX3G@206389|Rhodocyclales	206389|Rhodocyclales	S	Iron-sulphur cluster biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Fe-S_biosyn
k59_1426086_2	159087.Daro_1514	2.5e-46	156.0	COG0694@1|root,COG0822@1|root,COG0694@2|Bacteria,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,2VJE9@28216|Betaproteobacteria,2KVIQ@206389|Rhodocyclales	206389|Rhodocyclales	CO	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins	-	-	-	ko:K13819	-	-	-	-	ko00000	-	-	-	Fer2_BFD,NifU,NifU_N
k59_1016143_1	1165841.SULAR_00200	0.000162	42.4	COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,42TWY@68525|delta/epsilon subdivisions,2YPX1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
k59_1717223_1	709032.Sulku_2356	6.43e-121	350.0	COG0124@1|root,COG0124@2|Bacteria,1QUJQ@1224|Proteobacteria,42NX2@68525|delta/epsilon subdivisions,2YN2F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	PFAM tRNA synthetase class II (G H P and S)	hisZ	-	-	-	-	-	-	-	-	-	-	-	tRNA-synt_His
k59_134414_1	1120983.KB894573_gene241	3.33e-08	56.6	COG1218@1|root,COG1218@2|Bacteria,1N0GY@1224|Proteobacteria,2TT7B@28211|Alphaproteobacteria,1JNWA@119043|Rhodobiaceae	28211|Alphaproteobacteria	P	Inositol monophosphatase family	cysQ	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
k59_134414_2	1205753.A989_18275	2.34e-25	100.0	COG0494@1|root,COG0494@2|Bacteria,1RCX7@1224|Proteobacteria,1S3ZE@1236|Gammaproteobacteria,1X3RK@135614|Xanthomonadales	135614|Xanthomonadales	L	ADP-ribose diphosphatase	nudE	-	-	ko:K08312	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
k59_838232_1	1249480.B649_01535	1.48e-99	319.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YMHP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF,PAS_9
k59_1717229_2	1249480.B649_01930	4.31e-161	472.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1RGCV@1224|Proteobacteria,43CEF@68525|delta/epsilon subdivisions,2YTC1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_250131_1	159087.Daro_2713	3.46e-122	351.0	COG4181@1|root,COG4181@2|Bacteria,1MXG9@1224|Proteobacteria,2VI54@28216|Betaproteobacteria,2KUMK@206389|Rhodocyclales	206389|Rhodocyclales	Q	ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_776859_2	1304883.KI912532_gene2925	2.68e-59	195.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,2VIY4@28216|Betaproteobacteria,2KVUX@206389|Rhodocyclales	206389|Rhodocyclales	M	COG2148 Sugar transferases involved in lipopolysaccharide synthesis	sthA	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
k59_663772_1	1165841.SULAR_09179	6.91e-113	350.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07648,ko:K07679	ko02020,ko02026,ko05133,map02020,map02026,map05133	M00456,M00477	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	7TMR-DISM_7TM,GAF_2,HATPase_c,HisKA,Hpt,PAS,Response_reg
k59_1658894_1	159087.Daro_1501	7.52e-53	178.0	COG2710@1|root,COG2710@2|Bacteria,1MWAJ@1224|Proteobacteria,2VJ11@28216|Betaproteobacteria,2KVBY@206389|Rhodocyclales	206389|Rhodocyclales	C	Nitrogenase component 1 type Oxidoreductase	-	-	-	ko:K02587	-	-	-	-	ko00000	-	-	-	Oxidored_nitro
k59_1658894_2	159087.Daro_1505	1.26e-91	280.0	COG2710@1|root,COG2710@2|Bacteria,1MWSX@1224|Proteobacteria,2VJNA@28216|Betaproteobacteria,2KV3F@206389|Rhodocyclales	206389|Rhodocyclales	C	Nitrogenase component 1 type Oxidoreductase	-	-	-	ko:K02592	-	-	-	-	ko00000	-	-	-	Oxidored_nitro
k59_189870_1	1249480.B649_05060	2.11e-79	249.0	COG0840@1|root,COG0840@2|Bacteria,1R486@1224|Proteobacteria,42Q5Y@68525|delta/epsilon subdivisions,2YNT8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	CZB,MCPsignal
k59_189870_2	1249480.B649_05065	9.57e-99	288.0	COG3829@1|root,COG3829@2|Bacteria,1RH32@1224|Proteobacteria,42SY8@68525|delta/epsilon subdivisions,2YPGC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	PAS sensor protein	-	-	-	-	-	-	-	-	-	-	-	-	PAS_3
k59_189870_3	1249480.B649_05070	5.05e-59	194.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2YNK5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DEAD box helicase family	dbpA	-	3.6.4.13	ko:K05591	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DEAD,DbpA,Helicase_C
k59_1544074_1	159087.Daro_4140	6.22e-85	261.0	COG1565@1|root,COG1565@2|Bacteria,1N3CJ@1224|Proteobacteria,2VHBE@28216|Betaproteobacteria,2KUAS@206389|Rhodocyclales	206389|Rhodocyclales	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
k59_15377_1	1249480.B649_10610	2.78e-182	520.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2YNUU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	COG2804 Type II secretory pathway ATPase PulE Tfp pilus assembly pathway ATPase PilB	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
k59_955995_1	312309.VF_A0481	5.46e-19	92.8	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	chemotaxis, protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,TarH
k59_425519_1	1172190.M947_03300	2.39e-55	184.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,42N6U@68525|delta/epsilon subdivisions,2YMCX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	lipid a biosynthesis	waaM	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
k59_1544108_1	159087.Daro_1293	2.83e-201	560.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,2VIVV@28216|Betaproteobacteria,2KUD7@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_1599883_2	1304883.KI912532_gene740	2.28e-35	130.0	COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,2VHR0@28216|Betaproteobacteria,2KUNT@206389|Rhodocyclales	206389|Rhodocyclales	T	Domain of unknown function (DUF3391)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3391,HD_5
k59_307045_1	1454004.AW11_01123	1.81e-47	159.0	COG0356@1|root,COG0356@2|Bacteria,1RBEV@1224|Proteobacteria,2WGC1@28216|Betaproteobacteria	28216|Betaproteobacteria	C	it plays a direct role in the translocation of protons across the membrane	-	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
k59_307045_2	1454004.AW11_01122	1.13e-16	73.2	2E70X@1|root,331JP@2|Bacteria,1N81S@1224|Proteobacteria,2W4A4@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
k59_895841_1	1249480.B649_09800	3.74e-63	201.0	COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,42ND2@68525|delta/epsilon subdivisions,2YMQ0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_2
k59_895841_2	1537917.JU82_08375	2.96e-26	106.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,42MET@68525|delta/epsilon subdivisions,2YMVE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	phosphomannomutase	glmM_1	-	5.4.2.2,5.4.2.8	ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_1599884_1	1304883.KI912532_gene111	4.16e-107	314.0	COG0845@1|root,COG0845@2|Bacteria,1MX8W@1224|Proteobacteria,2VJNH@28216|Betaproteobacteria,2KXU5@206389|Rhodocyclales	206389|Rhodocyclales	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
k59_895847_2	1537917.JU82_02050	3.52e-52	177.0	COG1538@1|root,COG1538@2|Bacteria,1Q5X2@1224|Proteobacteria,43200@68525|delta/epsilon subdivisions,2YS78@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_1658990_1	709032.Sulku_1906	1.85e-53	185.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42SS2@68525|delta/epsilon subdivisions,2YRAM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	CZB,MCPsignal
k59_1858465_1	1537917.JU82_04260	1.11e-06	53.9	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2YMW5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,MCPsignal,dCache_2,sCache_2
k59_319351_1	709032.Sulku_0168	8.57e-89	275.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2YMIX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	ctsE	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
k59_505554_1	387093.SUN_0677	1.43e-121	357.0	COG3039@1|root,COG3039@2|Bacteria,1MVDK@1224|Proteobacteria,42TG6@68525|delta/epsilon subdivisions,2YSBE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Transposase domain (DUF772)	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF772
k59_86275_1	387093.SUN_0537	5.69e-96	305.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,42MN5@68525|delta/epsilon subdivisions,2YN0Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	DUF294,GlnD_UR_UTase,HD,NTP_transf_2
k59_568013_2	438753.AZC_3597	7.23e-24	100.0	COG0749@1|root,COG0749@2|Bacteria,1P27P@1224|Proteobacteria,2TVEI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	DNA polymerase family A	-	-	-	-	-	-	-	-	-	-	-	-	DNA_pol_A
k59_911710_1	398527.Bphyt_1881	3.07e-10	63.5	COG5267@1|root,COG5267@2|Bacteria,1MWJK@1224|Proteobacteria,2VIYI@28216|Betaproteobacteria,1KH1C@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
k59_911710_2	1123508.JH636440_gene2395	3.27e-17	82.8	COG4102@1|root,COG4102@2|Bacteria,2IYNP@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
k59_1090007_1	159087.Daro_1222	6.62e-129	378.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,2VH4P@28216|Betaproteobacteria,2KUNN@206389|Rhodocyclales	206389|Rhodocyclales	T	ATPase related to phosphate starvation-inducible protein PhoH	-	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
k59_1675385_1	1249480.B649_06820	4.64e-108	321.0	COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,42QJ2@68525|delta/epsilon subdivisions,2YNBV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COGs COG3864 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
k59_853585_1	1537917.JU82_04420	1.42e-73	227.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,42NEA@68525|delta/epsilon subdivisions,2YN5P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
k59_684823_1	472759.Nhal_1406	2.34e-36	133.0	COG2984@1|root,COG2984@2|Bacteria,1REID@1224|Proteobacteria,1S6J9@1236|Gammaproteobacteria,1WZUK@135613|Chromatiales	135613|Chromatiales	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
k59_728409_1	1249480.B649_06650	3.48e-62	199.0	COG2199@1|root,COG2199@2|Bacteria,1Q4Z5@1224|Proteobacteria,4306K@68525|delta/epsilon subdivisions,2YRSF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	diguanylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_728409_2	1249480.B649_09870	7.71e-32	127.0	COG1629@1|root,COG4771@2|Bacteria,1RKNG@1224|Proteobacteria,43DI3@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	Outer membrane protein beta-barrel family	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_1319491_1	1165841.SULAR_08859	6.82e-26	104.0	COG2046@1|root,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,42NAI@68525|delta/epsilon subdivisions,2YME3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	sulfate adenylyltransferase	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
k59_1319491_2	1165841.SULAR_08854	3.37e-110	325.0	COG2204@1|root,COG2204@2|Bacteria,1QUIV@1224|Proteobacteria,42M4N@68525|delta/epsilon subdivisions,2YMIT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_28533_1	1537917.JU82_11265	7.46e-52	173.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,42NFK@68525|delta/epsilon subdivisions,2YNST@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_1382326_1	1173029.JH980292_gene3536	5.11e-44	159.0	COG5001@1|root,COG5001@2|Bacteria,1G2MB@1117|Cyanobacteria,1H722@1150|Oscillatoriales	1117|Cyanobacteria	T	COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_1616604_1	1123517.JOMR01000001_gene1972	1.67e-111	333.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,1RM7I@1236|Gammaproteobacteria,460AT@72273|Thiotrichales	72273|Thiotrichales	C	Belongs to the heme-copper respiratory oxidase family	-	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
k59_381021_1	1249480.B649_05255	2.98e-62	202.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42QH4@68525|delta/epsilon subdivisions,2YNGA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	JKL	Belongs to the DEAD box helicase family	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
k59_1616616_1	326297.Sama_2951	9.9e-75	236.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,1RPH3@1236|Gammaproteobacteria,2Q9DZ@267890|Shewanellaceae	1236|Gammaproteobacteria	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,Response_reg
k59_505613_1	583345.Mmol_2221	4.25e-24	98.6	COG3170@1|root,COG3170@2|Bacteria,1N3SZ@1224|Proteobacteria,2VU3V@28216|Betaproteobacteria,2KMWK@206350|Nitrosomonadales	206350|Nitrosomonadales	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
k59_505613_2	583345.Mmol_2220	3.59e-78	246.0	COG0144@1|root,COG0144@2|Bacteria,1MV2Q@1224|Proteobacteria,2VI1D@28216|Betaproteobacteria,2KKKZ@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N
k59_1039439_2	1123518.ARWI01000001_gene1345	9.71e-09	57.0	COG0715@1|root,COG0715@2|Bacteria,1NV0U@1224|Proteobacteria,1SNZC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	-
k59_266187_2	317025.Tcr_1091	1.13e-59	193.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,1RM8Z@1236|Gammaproteobacteria,460B4@72273|Thiotrichales	72273|Thiotrichales	O	HflC and HflK could regulate a protease	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
k59_1272013_1	1249480.B649_04905	1.35e-120	351.0	COG3842@1|root,COG3842@2|Bacteria,1RC3N@1224|Proteobacteria,42MSG@68525|delta/epsilon subdivisions,2YMX7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	ATP-binding protein	modC	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran
k59_1272013_2	709032.Sulku_1136	5.65e-13	65.9	COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,42UAA@68525|delta/epsilon subdivisions,2YS1D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	peptidyl-prolyl	-	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
k59_88455_1	1123400.KB904813_gene3039	6.87e-28	107.0	COG4705@1|root,COG4705@2|Bacteria,1MVMJ@1224|Proteobacteria,1S35X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	membrane-anchored protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF347
k59_507737_1	159087.Daro_0222	1.05e-94	295.0	COG0480@1|root,COG0480@2|Bacteria,1MVVY@1224|Proteobacteria,2VKWB@28216|Betaproteobacteria,2KVQ3@206389|Rhodocyclales	206389|Rhodocyclales	J	COG0480 Translation elongation factors (GTPases)	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
k59_570952_1	102125.Xen7305DRAFT_00024850	3.21e-17	86.7	COG1874@1|root,COG1874@2|Bacteria,1GH6K@1117|Cyanobacteria,3VNCP@52604|Pleurocapsales	1117|Cyanobacteria	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1794315_3	1249480.B649_02135	5.08e-260	718.0	COG0642@1|root,COG2205@2|Bacteria,1QUJ5@1224|Proteobacteria,42NJC@68525|delta/epsilon subdivisions,2YMGQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	cosS	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_507741_1	1249480.B649_01765	3.06e-145	419.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,42ME0@68525|delta/epsilon subdivisions,2YMC8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_321012_1	1537917.JU82_00585	1.29e-83	254.0	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,42P86@68525|delta/epsilon subdivisions,2YN53@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	iIT341.HP1418	MurB_C
k59_687492_1	159087.Daro_4043	5.07e-22	93.6	COG0683@1|root,COG0683@2|Bacteria,1MVV2@1224|Proteobacteria,2VJE6@28216|Betaproteobacteria,2KUS7@206389|Rhodocyclales	206389|Rhodocyclales	E	amino acid	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_687492_2	159087.Daro_4042	3.49e-60	190.0	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,2VHY3@28216|Betaproteobacteria,2KVAA@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
k59_1677619_1	1123518.ARWI01000001_gene2205	6.66e-40	145.0	COG1639@1|root,COG1639@2|Bacteria,1R4P9@1224|Proteobacteria,1RRBF@1236|Gammaproteobacteria,463MU@72273|Thiotrichales	1236|Gammaproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_800249_1	1537917.JU82_10705	3.82e-79	247.0	COG0457@1|root,COG0457@2|Bacteria,1MXK4@1224|Proteobacteria,42PK9@68525|delta/epsilon subdivisions,2YNXX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
k59_1619034_1	1165841.SULAR_05948	2.18e-161	473.0	28N8G@1|root,2ZBCV@2|Bacteria,1NMB1@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1207800_1	159087.Daro_1731	3.55e-23	92.0	COG0590@1|root,COG0590@2|Bacteria,1RHM4@1224|Proteobacteria,2VX9D@28216|Betaproteobacteria,2KYW7@206389|Rhodocyclales	206389|Rhodocyclales	FJ	MafB19-like deaminase	-	-	-	-	-	-	-	-	-	-	-	-	dCMP_cyt_deam_1
k59_1207800_2	159087.Daro_1730	1.26e-37	129.0	2FHBX@1|root,34967@2|Bacteria,1P0BQ@1224|Proteobacteria,2W40F@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1207808_1	709032.Sulku_2476	1.37e-53	183.0	COG3437@1|root,COG4191@1|root,COG3437@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43DAR@68525|delta/epsilon subdivisions,2YTHT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HD
k59_1207808_2	709032.Sulku_2475	2.5e-29	107.0	COG0226@1|root,COG0226@2|Bacteria,1N3EC@1224|Proteobacteria,42XZP@68525|delta/epsilon subdivisions,2YSV9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1794357_1	1026882.MAMP_02011	8.92e-05	50.4	COG2199@1|root,COG3706@2|Bacteria,1NC00@1224|Proteobacteria,1S49X@1236|Gammaproteobacteria,462HY@72273|Thiotrichales	72273|Thiotrichales	T	diguanylate cyclase	-	-	2.7.7.65	ko:K13590	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF
k59_1274644_1	1234595.C725_0463	1.69e-89	280.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2TTB9@28211|Alphaproteobacteria,4BT9B@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	Carboxyl transferase domain	MA20_27300	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
k59_321075_2	411901.BACCAC_02078	1.47e-11	65.5	COG2172@1|root,COG2172@2|Bacteria,4NRAA@976|Bacteroidetes,2FTQ6@200643|Bacteroidia,4ARMF@815|Bacteroidaceae	976|Bacteroidetes	T	Histidine kinase-like ATPase domain	rsbW	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
k59_1619078_2	1249480.B649_11350	2.79e-23	92.4	COG2863@1|root,COG2863@2|Bacteria,1PGQN@1224|Proteobacteria,42VXH@68525|delta/epsilon subdivisions,2YSTK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
k59_1861238_1	157783.LK03_15625	3.51e-46	157.0	COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,1RN71@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	ABC transporter, periplasmic molybdate-binding protein	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
k59_1861238_2	717772.THIAE_07950	1.99e-104	308.0	COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,1RRDV@1236|Gammaproteobacteria,461NM@72273|Thiotrichales	72273|Thiotrichales	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
k59_383369_1	1304883.KI912532_gene33	3.76e-174	514.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria,2KUIP@206389|Rhodocyclales	206389|Rhodocyclales	T	Histidine Phosphotransfer domain	-	-	2.7.13.1	ko:K05962	-	-	-	-	ko00000,ko01000	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,Response_reg
k59_1677710_1	1249480.B649_07615	1.53e-16	80.1	COG1315@1|root,COG1315@2|Bacteria,1R5P6@1224|Proteobacteria,42MAS@68525|delta/epsilon subdivisions,2YM7Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Flagellar Assembly Protein A	-	-	-	-	-	-	-	-	-	-	-	-	FapA
k59_1677710_2	1537917.JU82_06825	3.31e-281	779.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MA6@68525|delta/epsilon subdivisions,2YMMG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	COG0841 Cation multidrug efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_730318_1	709032.Sulku_0117	1.28e-100	300.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,42N69@68525|delta/epsilon subdivisions,2YN3J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
k59_1736222_2	90814.KL370891_gene1656	2.51e-34	121.0	COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,1S5WU@1236|Gammaproteobacteria,460ZG@72273|Thiotrichales	72273|Thiotrichales	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
k59_444205_1	395494.Galf_2934	2.87e-111	325.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,2VJBW@28216|Betaproteobacteria,44V00@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
k59_1736229_1	1304883.KI912532_gene2926	6.08e-95	297.0	COG4191@1|root,COG4191@2|Bacteria,1MU55@1224|Proteobacteria,2VIZD@28216|Betaproteobacteria,2KV0R@206389|Rhodocyclales	206389|Rhodocyclales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
k59_1567726_1	573061.Clocel_3945	8.47e-22	97.4	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,2490U@186801|Clostridia,36EG3@31979|Clostridiaceae	186801|Clostridia	Q	TIGRFAM amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_978079_1	1313301.AUGC01000014_gene2485	2.61e-30	116.0	COG0682@1|root,COG0682@2|Bacteria,4NFP7@976|Bacteroidetes	976|Bacteroidetes	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	-	-	-	-	-	-	-	-	-	LGT
k59_730369_1	62928.azo2930	9.49e-124	369.0	COG2414@1|root,COG2414@2|Bacteria,1MWBB@1224|Proteobacteria,2VJ8P@28216|Betaproteobacteria,2KVX2@206389|Rhodocyclales	206389|Rhodocyclales	C	aldehyde ferredoxin oxidoreductase	aorA	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
k59_507932_1	1165841.SULAR_02738	6.12e-24	97.4	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,42MYJ@68525|delta/epsilon subdivisions,2YN0I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS
k59_507932_2	387093.SUN_1199	6.15e-39	139.0	COG0479@1|root,COG0479@2|Bacteria	2|Bacteria	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_88626_1	709032.Sulku_0513	1.61e-62	204.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,42M14@68525|delta/epsilon subdivisions,2YMWB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Biotin carboxylase	pycA	-	6.3.4.14,6.4.1.1,6.4.1.2	ko:K01959,ko:K01961	ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko01230,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212,map01230	M00082,M00173,M00376,M00620	R00344,R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
k59_88626_2	1537917.JU82_11830	4.71e-57	188.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,42MPS@68525|delta/epsilon subdivisions,2YMSR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	apolipoprotein N-acyltransferase	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
k59_571081_1	1249480.B649_03325	2.96e-59	201.0	COG1807@1|root,COG1807@2|Bacteria,1Q901@1224|Proteobacteria,42MGX@68525|delta/epsilon subdivisions,2YNER@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
k59_321207_1	709032.Sulku_2005	2.2e-14	72.0	COG1433@1|root,COG1433@2|Bacteria	2|Bacteria	S	nitrogen fixation	VPA0323	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,Nitro_FeMo-Co,ZT_dimer
k59_444270_1	709032.Sulku_2086	9.02e-102	305.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2YNF8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	flgR	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_1155232_1	709032.Sulku_1482	2.08e-125	375.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42MS0@68525|delta/epsilon subdivisions,2YMTX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_1155236_1	1537917.JU82_03895	2.09e-86	266.0	COG1413@1|root,COG1413@2|Bacteria,1Q1TE@1224|Proteobacteria,42UC8@68525|delta/epsilon subdivisions,2YPXK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_211633_1	159087.Daro_0301	2.68e-70	218.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,2VHEW@28216|Betaproteobacteria,2KUBV@206389|Rhodocyclales	206389|Rhodocyclales	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
k59_1861362_1	159087.Daro_1135	1.76e-133	387.0	COG0477@1|root,COG2814@2|Bacteria,1MV79@1224|Proteobacteria,2VMJE@28216|Betaproteobacteria,2KVTK@206389|Rhodocyclales	206389|Rhodocyclales	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_1619251_1	1249480.B649_04765	3.11e-06	47.8	COG3190@1|root,COG3190@2|Bacteria,1Q1CX@1224|Proteobacteria,42PAU@68525|delta/epsilon subdivisions,2YP0B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1619251_2	1249480.B649_04760	7.62e-65	202.0	COG0790@1|root,COG0790@2|Bacteria	2|Bacteria	S	beta-lactamase activity	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
k59_1619251_3	709032.Sulku_1539	6.46e-13	64.3	2AIYJ@1|root,319GA@2|Bacteria,1Q2NX@1224|Proteobacteria,42W0X@68525|delta/epsilon subdivisions,2YQ6Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_624956_1	1304883.KI912532_gene1079	9.25e-38	130.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,2VR4Y@28216|Betaproteobacteria,2KWH7@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
k59_624956_2	640081.Dsui_0385	2.88e-44	150.0	COG1418@1|root,COG1418@2|Bacteria,1RH6M@1224|Proteobacteria,2VRKW@28216|Betaproteobacteria,2KZQG@206389|Rhodocyclales	206389|Rhodocyclales	S	mRNA catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_624978_1	867845.KI911784_gene2830	1.15e-23	99.8	COG0745@1|root,COG0745@2|Bacteria,2G6H6@200795|Chloroflexi,3752R@32061|Chloroflexia	32061|Chloroflexia	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_444333_1	1123073.KB899244_gene283	7.39e-23	97.4	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,1X55Q@135614|Xanthomonadales	135614|Xanthomonadales	EH	component I	pabB	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
k59_444333_2	1026882.MAMP_02246	7.68e-06	50.8	COG0115@1|root,COG0115@2|Bacteria,1MZAK@1224|Proteobacteria,1RPPG@1236|Gammaproteobacteria,460Q9@72273|Thiotrichales	72273|Thiotrichales	EH	PFAM Aminotransferase, class IV	-	-	4.1.3.38	ko:K02619	ko00790,map00790	-	R05553	RC01843,RC02148	ko00000,ko00001,ko01000	-	-	-	Aminotran_4
k59_914191_2	1114964.L485_18985	1.06e-07	54.7	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2UP6H@28211|Alphaproteobacteria,2JZX5@204457|Sphingomonadales	204457|Sphingomonadales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_1567832_1	709032.Sulku_2486	1.95e-96	290.0	COG1149@1|root,COG1149@2|Bacteria,1R1KA@1224|Proteobacteria,43DAS@68525|delta/epsilon subdivisions,2YTHU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
k59_1567832_2	709032.Sulku_2487	1.69e-112	325.0	COG3381@1|root,COG3381@2|Bacteria,1R97V@1224|Proteobacteria,4306E@68525|delta/epsilon subdivisions,2YRX0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Nitrate reductase delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_del
k59_88708_1	1249480.B649_04790	1.11e-100	297.0	COG1639@1|root,COG1639@2|Bacteria,1RAH3@1224|Proteobacteria,42PRF@68525|delta/epsilon subdivisions,2YNUX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Signal transduction protein	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_571157_1	159087.Daro_4077	1.13e-72	226.0	COG0583@1|root,COG0583@2|Bacteria,1MWY0@1224|Proteobacteria,2VIVF@28216|Betaproteobacteria,2KUNM@206389|Rhodocyclales	206389|Rhodocyclales	K	LysR substrate binding domain	-	-	-	ko:K03566	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
k59_687843_1	159087.Daro_2796	8.39e-85	254.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,2VQTQ@28216|Betaproteobacteria,2KW1F@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
k59_444391_2	1165841.SULAR_06903	1.15e-41	150.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,42M09@68525|delta/epsilon subdivisions,2YMWR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
k59_1501015_1	1537917.JU82_10505	3.18e-97	288.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,42MW0@68525|delta/epsilon subdivisions,2YM9U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
k59_1230509_2	1165841.SULAR_08864	4.9e-81	243.0	COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,42RMF@68525|delta/epsilon subdivisions,2YP6U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	pgpA	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
k59_1523749_1	159087.Daro_2983	2.11e-20	87.0	COG2976@1|root,COG2976@2|Bacteria,1N117@1224|Proteobacteria,2VSHE@28216|Betaproteobacteria,2KWT1@206389|Rhodocyclales	206389|Rhodocyclales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TPR_21
k59_1523749_2	159087.Daro_2982	3.33e-41	147.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,2VHH5@28216|Betaproteobacteria,2KVKZ@206389|Rhodocyclales	206389|Rhodocyclales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamB	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
k59_467190_2	709032.Sulku_0341	7.98e-12	63.5	2BME9@1|root,32FYS@2|Bacteria,1Q6HK@1224|Proteobacteria,4335F@68525|delta/epsilon subdivisions,2YSJQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_467254_1	1101195.Meth11DRAFT_2272	4.93e-24	98.6	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,2VJS2@28216|Betaproteobacteria,2KMH0@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
k59_406233_2	396588.Tgr7_1158	1.25e-124	362.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,1RMHN@1236|Gammaproteobacteria,1WX9V@135613|Chromatiales	135613|Chromatiales	E	TIGRFAM methionine aminopeptidase, type I	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
k59_406233_3	998674.ATTE01000001_gene2269	2.58e-45	153.0	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,1RN0Z@1236|Gammaproteobacteria,45ZU2@72273|Thiotrichales	72273|Thiotrichales	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
k59_232243_1	159087.Daro_0658	6.11e-57	186.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,2VHX4@28216|Betaproteobacteria,2KV65@206389|Rhodocyclales	206389|Rhodocyclales	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
k59_232243_2	1304883.KI912532_gene255	9.67e-09	55.8	COG2198@1|root,COG2206@1|root,COG2198@2|Bacteria,COG2206@2|Bacteria,1RA8P@1224|Proteobacteria,2VNF3@28216|Betaproteobacteria,2KVB7@206389|Rhodocyclales	206389|Rhodocyclales	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_5,Hpt
k59_1700506_1	1537917.JU82_01810	5.33e-132	375.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,42M5X@68525|delta/epsilon subdivisions,2YMCY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
k59_1523842_1	1123354.AUDR01000015_gene322	1.65e-27	110.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,2VHVA@28216|Betaproteobacteria,1KRHJ@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
k59_1523842_2	292415.Tbd_0620	8.28e-88	264.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,2VIQF@28216|Betaproteobacteria,1KRZE@119069|Hydrogenophilales	119069|Hydrogenophilales	M	DAHP synthetase I family	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
k59_1408045_1	1121035.AUCH01000007_gene562	1.03e-05	46.2	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2VJ55@28216|Betaproteobacteria,2KUZP@206389|Rhodocyclales	206389|Rhodocyclales	H	COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase	ilvI	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_1408045_2	159087.Daro_3074	4.75e-102	296.0	COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,2VH1H@28216|Betaproteobacteria,2KV5Y@206389|Rhodocyclales	206389|Rhodocyclales	E	Acetolactate synthase small	ilvH	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_5,ALS_ss_C
k59_1408049_1	1249480.B649_09055	7.91e-46	154.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,42QV4@68525|delta/epsilon subdivisions,2YMTK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
k59_232310_1	1537917.JU82_03295	6.94e-247	684.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,42NDS@68525|delta/epsilon subdivisions,2YN0K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	DNA recombination protein	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
k59_291398_1	1249480.B649_06475	1.53e-103	306.0	COG1639@1|root,COG1639@2|Bacteria,1RAH3@1224|Proteobacteria,42PRF@68525|delta/epsilon subdivisions,2YMRX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Signal transduction protein	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_876678_1	709032.Sulku_0332	9.75e-76	234.0	COG1587@1|root,COG1587@2|Bacteria,1NMTP@1224|Proteobacteria,42T0U@68525|delta/epsilon subdivisions,2YPN4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Uroporphyrinogen-III synthase	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
k59_291405_1	709032.Sulku_1951	4.09e-75	233.0	COG0642@1|root,COG2205@2|Bacteria,1RK1D@1224|Proteobacteria,42R91@68525|delta/epsilon subdivisions,2YNX3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
k59_291417_1	159087.Daro_3572	1.2e-31	114.0	2A515@1|root,2ZRWF@2|Bacteria,1P5VN@1224|Proteobacteria,2W62Q@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_232348_1	90814.KL370891_gene1296	8.07e-08	53.9	COG2928@1|root,COG2928@2|Bacteria,1MWT5@1224|Proteobacteria,1S3MU@1236|Gammaproteobacteria,461RE@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
k59_232348_2	1276756.AUEX01000003_gene662	1.29e-65	217.0	COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,2VHXI@28216|Betaproteobacteria,4AB63@80864|Comamonadaceae	28216|Betaproteobacteria	F	thymidine phosphorylase	-	-	2.4.2.4	ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
k59_291423_2	580332.Slit_0855	3.48e-34	118.0	2E5WI@1|root,330KJ@2|Bacteria,1N6RI@1224|Proteobacteria,2VXJ8@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Nif11 domain	-	-	-	-	-	-	-	-	-	-	-	-	Nif11
k59_752190_1	709032.Sulku_1308	2.36e-86	262.0	28M05@1|root,32SJ0@2|Bacteria,1N115@1224|Proteobacteria,42ZGF@68525|delta/epsilon subdivisions,2YRPD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_109014_1	1502770.JQMG01000001_gene592	4.16e-105	315.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,2VHYE@28216|Betaproteobacteria,2KKT7@206350|Nitrosomonadales	206350|Nitrosomonadales	E	TIGRFAM glutamine synthetase, type I	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k59_876781_1	1537917.JU82_03955	5.23e-26	101.0	COG1192@1|root,COG1192@2|Bacteria,1N5CA@1224|Proteobacteria,42RDX@68525|delta/epsilon subdivisions,2YQN4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	involved in chromosome partitioning	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
k59_1815561_1	1537917.JU82_10040	7.59e-62	202.0	COG3174@1|root,COG3174@2|Bacteria,1NDBI@1224|Proteobacteria,42QBM@68525|delta/epsilon subdivisions,2YNPT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	MgtC family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
k59_1408203_1	709032.Sulku_0143	1.99e-84	274.0	COG0715@1|root,COG0834@1|root,COG4191@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PNA@68525|delta/epsilon subdivisions,2YTBI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EPT	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,NMT1,SBP_bac_3
k59_1815580_1	1537917.JU82_06655	1.37e-42	142.0	COG0177@1|root,COG0177@2|Bacteria,1RAK3@1224|Proteobacteria,42M4V@68525|delta/epsilon subdivisions,2YNKT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	tigr02757	-	-	-	-	-	-	-	-	-	-	-	-	DUF2400
k59_1815580_2	1249480.B649_07340	3.16e-66	219.0	COG5001@1|root,COG5001@2|Bacteria,1R4H0@1224|Proteobacteria	1224|Proteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_291484_1	395494.Galf_1756	9.79e-133	400.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,2VJIJ@28216|Betaproteobacteria,44V61@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
k59_1347513_1	1537917.JU82_10935	1.2e-137	406.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2YN0B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
k59_467572_2	1304883.KI912532_gene2625	2.8e-26	105.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,2VHU7@28216|Betaproteobacteria,2KVCM@206389|Rhodocyclales	206389|Rhodocyclales	NU	twitching motility protein	-	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_876834_1	159087.Daro_3777	8.1e-106	324.0	28J5I@1|root,2Z91C@2|Bacteria,1QVI2@1224|Proteobacteria,2VN9N@28216|Betaproteobacteria,2KV6Q@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF1302)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1302
k59_350558_1	1249480.B649_01935	2.59e-51	168.0	COG0745@1|root,COG0745@2|Bacteria,1QUJR@1224|Proteobacteria,42NQS@68525|delta/epsilon subdivisions,2YN0F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_350575_1	709032.Sulku_2033	4.4e-30	114.0	COG0309@1|root,COG0309@2|Bacteria,1MVCC@1224|Proteobacteria,42M3M@68525|delta/epsilon subdivisions,2YMY3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	hydrogenase expression formation protein	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
k59_350575_2	1537917.JU82_03445	4.9e-55	174.0	COG0375@1|root,COG0375@2|Bacteria,1MZJH@1224|Proteobacteria,42TGG@68525|delta/epsilon subdivisions,2YPWP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
k59_1819257_1	1323663.AROI01000035_gene1398	0.000727	41.6	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,1RNPZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	GO:0000724,GO:0000725,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
k59_1819257_2	1123517.JOMR01000001_gene1299	6.5e-48	162.0	COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,1RP84@1236|Gammaproteobacteria,460FP@72273|Thiotrichales	72273|Thiotrichales	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
k59_756359_1	159087.Daro_2191	1.44e-96	290.0	COG1876@1|root,COG1876@2|Bacteria,1MXWT@1224|Proteobacteria,2VPJ2@28216|Betaproteobacteria,2KX3A@206389|Rhodocyclales	206389|Rhodocyclales	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	ko:K17733	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M15_4
k59_350705_1	1537917.JU82_09400	3.52e-96	299.0	COG0068@1|root,COG0068@2|Bacteria,1Q0S6@1224|Proteobacteria,42SF1@68525|delta/epsilon subdivisions,2YPJ0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	HypF finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HYPF
k59_350736_1	243164.DET0151	9.82e-20	88.2	COG1451@1|root,COG1451@2|Bacteria,2G7C0@200795|Chloroflexi,34CZ9@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
k59_350745_1	1537917.JU82_09590	5.75e-81	250.0	COG1373@1|root,COG1373@2|Bacteria,1QP8R@1224|Proteobacteria,42SQ9@68525|delta/epsilon subdivisions,2YPG4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	ATPase (AAA	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14
k59_350767_1	709032.Sulku_2097	8.32e-20	92.0	COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,42NCS@68525|delta/epsilon subdivisions,2YNUR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	Outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
k59_112855_1	159087.Daro_3748	1.51e-130	383.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VHGR@28216|Betaproteobacteria,2KUI9@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the aldehyde dehydrogenase family	gabD	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_112859_1	159087.Daro_3729	2.07e-95	284.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,2VHK3@28216|Betaproteobacteria,2KUJ6@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
k59_350875_1	983917.RGE_08830	8.05e-43	167.0	COG0642@1|root,COG0784@1|root,COG0834@1|root,COG2198@1|root,COG2461@1|root,COG0784@2|Bacteria,COG0834@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,COG2461@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria,1KJCZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	4HB_MCP_1,HATPase_c,HisKA,Hpt,PAS,PAS_4,PAS_8,PAS_9,Response_reg,SBP_bac_3
k59_112902_1	1537917.JU82_09590	1.69e-57	188.0	COG1373@1|root,COG1373@2|Bacteria,1QP8R@1224|Proteobacteria,42SQ9@68525|delta/epsilon subdivisions,2YPG4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	ATPase (AAA	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14
k59_112902_2	1249480.B649_00735	9.02e-44	147.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,42REG@68525|delta/epsilon subdivisions,2YP63@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
k59_756639_1	1121403.AUCV01000010_gene1405	1.18e-67	219.0	COG0859@1|root,COG0859@2|Bacteria,1PQIG@1224|Proteobacteria,42MUM@68525|delta/epsilon subdivisions,2WPZT@28221|Deltaproteobacteria,2MN6W@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
k59_351060_1	1165841.SULAR_08809	7.85e-38	132.0	COG3637@1|root,COG3637@2|Bacteria,1NC11@1224|Proteobacteria	1224|Proteobacteria	M	COG3637 Opacity protein and related surface antigens	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OmpA_membrane
k59_113269_2	326298.Suden_0476	9.5e-52	174.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,42SE9@68525|delta/epsilon subdivisions,2YPMA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the multicopper oxidase YfiH RL5 family	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
k59_113282_1	1537917.JU82_04980	3.7e-113	337.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,42N4K@68525|delta/epsilon subdivisions,2YMXB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
k59_351378_1	1132855.KB913035_gene293	1.04e-125	367.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,2VI3M@28216|Betaproteobacteria,2KKUY@206350|Nitrosomonadales	206350|Nitrosomonadales	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
k59_757099_1	76114.ebA5333	3.65e-51	182.0	COG4774@1|root,COG4774@2|Bacteria,1MV0X@1224|Proteobacteria,2VIQR@28216|Betaproteobacteria,2KVX3@206389|Rhodocyclales	206389|Rhodocyclales	P	receptor	-	-	-	ko:K16090	-	-	-	-	ko00000,ko02000	1.B.14.1.11	-	-	Plug,TonB_dep_Rec
k59_757140_1	709032.Sulku_0495	2.14e-110	329.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,42M94@68525|delta/epsilon subdivisions,2YMQM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
k59_113464_2	1197906.CAJQ02000023_gene2207	9.15e-30	112.0	COG0279@1|root,COG0279@2|Bacteria,1NVIE@1224|Proteobacteria,2U8QT@28211|Alphaproteobacteria,3JY4C@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
k59_113557_2	640081.Dsui_1869	1.04e-45	149.0	2DNV8@1|root,32ZAX@2|Bacteria,1R3MW@1224|Proteobacteria,2VWAR@28216|Betaproteobacteria,2KWYT@206389|Rhodocyclales	206389|Rhodocyclales	S	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
k59_113557_3	1304883.KI912532_gene2273	1.97e-48	167.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VKB9@28216|Betaproteobacteria,2KVQT@206389|Rhodocyclales	206389|Rhodocyclales	L	helicase superfamily c-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
k59_351853_1	1249480.B649_09055	5.37e-48	159.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,42QV4@68525|delta/epsilon subdivisions,2YMTK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
k59_351853_2	1249480.B649_09060	2.09e-41	141.0	COG0688@1|root,COG0688@2|Bacteria,1P7K4@1224|Proteobacteria,42TG5@68525|delta/epsilon subdivisions,2YQHE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	phosphatidylserine decarboxylase	-	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
k59_757444_1	159087.Daro_4121	2.43e-201	593.0	COG0247@1|root,COG0277@1|root,COG0479@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,COG0479@2|Bacteria,1MU43@1224|Proteobacteria,2VHYU@28216|Betaproteobacteria,2KUWB@206389|Rhodocyclales	206389|Rhodocyclales	C	FAD linked oxidase	-	-	-	-	-	-	-	-	-	-	-	-	CCG,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_8
k59_757444_2	556268.OFAG_01911	2.68e-11	62.4	COG0537@1|root,COG0537@2|Bacteria,1MZVD@1224|Proteobacteria,2VU7S@28216|Betaproteobacteria,474KD@75682|Oxalobacteraceae	28216|Betaproteobacteria	FG	HIT domain	hit	-	-	-	-	-	-	-	-	-	-	-	HIT
k59_351932_1	709032.Sulku_2246	6.21e-78	241.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,42ME1@68525|delta/epsilon subdivisions,2YMI9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
k59_351972_2	709032.Sulku_1423	6.53e-72	221.0	COG0319@1|root,COG0319@2|Bacteria,1Q9G0@1224|Proteobacteria,42SJD@68525|delta/epsilon subdivisions,2YPJA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
k59_351998_1	159087.Daro_3288	4.5e-39	140.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,2VI2T@28216|Betaproteobacteria,2KUAY@206389|Rhodocyclales	206389|Rhodocyclales	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ASL_C,Lyase_1
k59_351998_3	1304883.KI912532_gene3236	9.21e-06	44.7	COG4390@1|root,COG4390@2|Bacteria,1N8RK@1224|Proteobacteria,2VUJW@28216|Betaproteobacteria,2KWNK@206389|Rhodocyclales	206389|Rhodocyclales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2322
k59_757700_1	1131814.JAFO01000001_gene2756	5.79e-09	63.9	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,2TR7W@28211|Alphaproteobacteria,3EY3T@335928|Xanthobacteraceae	28211|Alphaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_114073_1	709032.Sulku_0546	1.98e-133	388.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,42M15@68525|delta/epsilon subdivisions,2YMCI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
k59_114093_1	387093.SUN_1775	6.98e-30	111.0	COG0711@1|root,COG0711@2|Bacteria,1Q9TP@1224|Proteobacteria,42U87@68525|delta/epsilon subdivisions,2YPT1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
k59_114093_2	1165841.SULAR_05728	9.69e-51	164.0	COG0711@1|root,COG0711@2|Bacteria,1Q2G9@1224|Proteobacteria,42VN4@68525|delta/epsilon subdivisions,2YQBE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the ATPase B chain family	atpF'	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
k59_114099_1	1249480.B649_05330	6.8e-121	353.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MKR@68525|delta/epsilon subdivisions,2YN1A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Aminotransferase	aspB	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_757991_2	159087.Daro_0669	2.27e-132	380.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,2VNV2@28216|Betaproteobacteria,2KUPV@206389|Rhodocyclales	206389|Rhodocyclales	C	Cysteine-rich domain	-	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
k59_55842_1	1541959.KQ51_00282	1.39e-70	235.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria	2|Bacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ppsA	-	2.7.9.2,6.5.1.3	ko:K01007,ko:K14415	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PEP-utilizers,PPDK_N
k59_55894_1	1304883.KI912532_gene1721	1.89e-117	346.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,2VHP5@28216|Betaproteobacteria,2KUBF@206389|Rhodocyclales	206389|Rhodocyclales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petB	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
k59_55894_2	1129374.AJE_06191	4.19e-08	54.7	COG2857@1|root,COG2857@2|Bacteria,1QFU2@1224|Proteobacteria,1RN4Y@1236|Gammaproteobacteria,464CG@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Cytochrome C1	petC	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C1
k59_758425_1	1537917.JU82_03130	4.72e-11	68.6	COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,42MPN@68525|delta/epsilon subdivisions,2YMHV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Flagellar basal body protein	-	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bb_rod,Flg_bbr_C
k59_758488_1	583345.Mmol_0433	1.33e-117	355.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,2VHHU@28216|Betaproteobacteria,2KKFW@206350|Nitrosomonadales	206350|Nitrosomonadales	O	Collagenase	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
k59_1835683_1	159087.Daro_2188	7.75e-99	318.0	COG3523@1|root,COG3523@2|Bacteria,1MV3D@1224|Proteobacteria,2VJ0M@28216|Betaproteobacteria,2KV24@206389|Rhodocyclales	206389|Rhodocyclales	S	function. A few members resemble the ImcF protein, which has been proposed to be involved in Vibrio cholerae cell surface reorganisation that results in increased adherence to epithelial cells line and increased conjugation frequency	-	-	-	ko:K11891	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	IcmF-related,IcmF_C,ImcF-related_N
k59_954032_1	709032.Sulku_1277	7.5e-280	784.0	COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,1QTS5@1224|Proteobacteria,42MPY@68525|delta/epsilon subdivisions,2YMV7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	phosphate acetyltransferase	pta	-	2.3.1.8	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,DRTGG,PTA_PTB
k59_484778_1	159087.Daro_0386	1.71e-87	267.0	COG3327@1|root,COG3327@2|Bacteria,1R4IF@1224|Proteobacteria,2VP5N@28216|Betaproteobacteria,2KVFG@206389|Rhodocyclales	206389|Rhodocyclales	K	PaaX family	-	-	-	ko:K02616	-	-	-	-	ko00000,ko03000	-	-	-	PaaX,PaaX_C
k59_1424102_2	1249480.B649_03785	2.09e-45	152.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,42PTX@68525|delta/epsilon subdivisions,2YMNS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
k59_1657105_1	387093.SUN_1616	3.34e-108	335.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,42KZ9@68525|delta/epsilon subdivisions,2YMS4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_893999_1	395494.Galf_1292	5.27e-86	268.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,2W9JS@28216|Betaproteobacteria,44W6R@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Bacterial sugar transferase	-	-	-	ko:K03606	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Bac_transf,CoA_binding_3
k59_423882_1	709032.Sulku_2360	2.96e-141	410.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,42NA4@68525|delta/epsilon subdivisions,2YN8R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EGP	transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
k59_423882_2	1537917.JU82_02170	3.07e-111	323.0	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,42NGT@68525|delta/epsilon subdivisions,2YN0R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
k59_423882_3	1249480.B649_11170	5.9e-58	186.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,42N67@68525|delta/epsilon subdivisions,2YMDK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
k59_1130732_2	1249480.B649_04650	1.19e-22	92.8	COG1338@1|root,COG1338@2|Bacteria,1MVBU@1224|Proteobacteria,42NDZ@68525|delta/epsilon subdivisions,2YMJ1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Plays a role in the flagellum-specific transport system	fliP	-	-	ko:K02419	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliP
k59_714772_2	1229205.BUPH_00643	0.000668	46.2	COG1309@1|root,COG1309@2|Bacteria,1RBT6@1224|Proteobacteria,2VQET@28216|Betaproteobacteria,1KFPA@119060|Burkholderiaceae	28216|Betaproteobacteria	K	regulatory protein TetR	-	-	-	ko:K19736	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_7,TetR_N
k59_544639_1	1165841.SULAR_05903	2.95e-94	276.0	COG3829@1|root,COG3829@2|Bacteria,1RH32@1224|Proteobacteria,42QQM@68525|delta/epsilon subdivisions,2YNZA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	signal transduction sensor histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PAS,PAS_3
k59_423902_1	1163617.SCD_n00156	3.25e-43	147.0	COG0842@1|root,COG0842@2|Bacteria,1N55T@1224|Proteobacteria,2VJ7R@28216|Betaproteobacteria	28216|Betaproteobacteria	V	Transport permease protein	nodJ	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
k59_423902_2	292415.Tbd_0277	5.45e-26	104.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2VI3G@28216|Betaproteobacteria,1KRFG@119069|Hydrogenophilales	119069|Hydrogenophilales	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K09695	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC_tran
k59_1481788_1	1537917.JU82_00725	2.06e-34	127.0	COG3228@1|root,COG3228@2|Bacteria,1RAHF@1224|Proteobacteria,42QKQ@68525|delta/epsilon subdivisions,2YMYQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the MtfA family	-	-	-	ko:K09933	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_M90
k59_1481788_2	572480.Arnit_2867	3e-10	56.2	2AIY2@1|root,319FT@2|Bacteria,1Q2M9@1224|Proteobacteria,42VXT@68525|delta/epsilon subdivisions,2YQDC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
k59_1130783_1	1537917.JU82_07845	9.88e-90	290.0	COG0755@1|root,COG1333@1|root,COG0755@2|Bacteria,COG1333@2|Bacteria,1RG0A@1224|Proteobacteria,42N37@68525|delta/epsilon subdivisions,2YMXW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Cytochrome c biogenesis protein	ccsBA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
k59_1130787_2	190486.XAC0341	1.42e-22	89.7	2E975@1|root,333FP@2|Bacteria,1NEX8@1224|Proteobacteria,1SEYE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1598319_1	666681.M301_0443	7.39e-54	175.0	COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,2VHF8@28216|Betaproteobacteria	28216|Betaproteobacteria	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
k59_1598319_2	666681.M301_0444	8.2e-23	88.2	COG3114@1|root,COG3114@2|Bacteria	2|Bacteria	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmD	GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009898,GO:0015886,GO:0016020,GO:0031224,GO:0031226,GO:0031235,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098552,GO:0098562,GO:1901678	-	ko:K02196	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.107	-	iB21_1397.B21_02084,iBWG_1329.BWG_1971,iE2348C_1286.E2348C_2342,iEC042_1314.EC042_2439,iEC55989_1330.EC55989_2451,iECABU_c1320.ECABU_c25320,iECBD_1354.ECBD_1462,iECB_1328.ECB_02125,iECDH10B_1368.ECDH10B_2355,iECDH1ME8569_1439.ECDH1ME8569_2133,iECD_1391.ECD_02125,iECED1_1282.ECED1_2663,iECH74115_1262.ECH74115_3335,iECIAI1_1343.ECIAI1_2280,iECIAI39_1322.ECIAI39_2336,iECNA114_1301.ECNA114_2290,iECO103_1326.ECO103_2673,iECO111_1330.ECO111_2934,iECO26_1355.ECO26_3124,iECOK1_1307.ECOK1_2432,iECP_1309.ECP_2238,iECS88_1305.ECS88_2345,iECSE_1348.ECSE_2466,iECSF_1327.ECSF_2079,iECSP_1301.ECSP_3077,iECUMN_1333.ECUMN_2533,iECs_1301.ECs3087,iEKO11_1354.EKO11_1558,iETEC_1333.ETEC_2332,iEcDH1_1363.EcDH1_1461,iEcE24377_1341.EcE24377A_2497,iEcHS_1320.EcHS_A2336,iEcSMS35_1347.EcSMS35_2346,iEcolC_1368.EcolC_1452,iJO1366.b2198,iLF82_1304.LF82_0276,iNRG857_1313.NRG857_11155,iSDY_1059.SDY_0880,iSFV_1184.SFV_2274,iSF_1195.SF2282,iSSON_1240.SSON_2256,iS_1188.S2412,iUMN146_1321.UM146_05815,iUMNK88_1353.UMNK88_2745,iUTI89_1310.UTI89_C2476,iY75_1357.Y75_RS11500,iZ_1308.Z3455,ic_1306.c2735	CcmD
k59_1598319_3	666681.M301_0445	3.95e-45	149.0	COG2332@1|root,COG2332@2|Bacteria,1RHN5@1224|Proteobacteria,2VRKZ@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
k59_484873_1	1249480.B649_05725	3.14e-72	223.0	COG2078@1|root,COG2078@2|Bacteria,1RJP4@1224|Proteobacteria,42SBG@68525|delta/epsilon subdivisions,2YP68@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM AMMECR1 domain protein	-	-	-	ko:K09141	-	-	-	-	ko00000	-	-	-	AMMECR1
k59_423931_1	159087.Daro_1123	7.86e-48	161.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,2VI71@28216|Betaproteobacteria,2KVRY@206389|Rhodocyclales	206389|Rhodocyclales	P	Phosphate transporter family	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
k59_423931_3	159087.Daro_1124	2.94e-11	58.5	COG5481@1|root,COG5481@2|Bacteria,1PU51@1224|Proteobacteria,2VXCJ@28216|Betaproteobacteria,2KXHJ@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF465)	-	-	-	-	-	-	-	-	-	-	-	-	DUF465
k59_1424200_1	1249480.B649_04365	4.17e-144	411.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,42N1R@68525|delta/epsilon subdivisions,2YMRZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_132534_2	1218352.B597_018635	7.12e-11	61.6	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,1RNPY@1236|Gammaproteobacteria,1YZZK@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	E	COG0826 Collagenase and related proteases	yegQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
k59_1363110_1	211165.AJLN01000104_gene6547	1.35e-53	195.0	COG3437@1|root,COG3829@1|root,COG5002@1|root,COG3437@2|Bacteria,COG3829@2|Bacteria,COG5002@2|Bacteria,1FZYQ@1117|Cyanobacteria,1JHAP@1189|Stigonemataceae	1117|Cyanobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_8,PAS_9,Response_reg
k59_601189_1	395494.Galf_2382	3.42e-94	279.0	COG4237@1|root,COG4237@2|Bacteria,1NAT8@1224|Proteobacteria,2VJTI@28216|Betaproteobacteria,44W5S@713636|Nitrosomonadales	28216|Betaproteobacteria	C	hydrogenase 4 membrane	hyfE	-	-	ko:K12140	-	-	-	-	ko00000,ko01000	-	-	-	-
k59_1070702_1	159087.Daro_1098	1.34e-127	369.0	COG0697@1|root,COG0697@2|Bacteria,1NEYM@1224|Proteobacteria,2VPAG@28216|Betaproteobacteria,2KW5W@206389|Rhodocyclales	206389|Rhodocyclales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_1303665_1	1123073.KB899244_gene355	3.62e-56	186.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,1RP9Z@1236|Gammaproteobacteria,1X4QY@135614|Xanthomonadales	135614|Xanthomonadales	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k59_1303665_2	1120977.JHUX01000008_gene420	1.36e-55	182.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,1RMEX@1236|Gammaproteobacteria,3NJMY@468|Moraxellaceae	1236|Gammaproteobacteria	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	GO:0000166,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	iPC815.YPO1374	Pyr_redox_2
k59_954163_1	387093.SUN_1255	3.31e-16	77.0	COG0810@1|root,COG0810@2|Bacteria,1MZB7@1224|Proteobacteria,42U57@68525|delta/epsilon subdivisions,2YQ1F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
k59_954163_2	572480.Arnit_2888	1.69e-86	267.0	28M05@1|root,2ZB16@2|Bacteria,1QVZ0@1224|Proteobacteria,43CB8@68525|delta/epsilon subdivisions,2YTAY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1072619_2	883126.HMPREF9710_00804	1.45e-17	82.0	COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,2VIPV@28216|Betaproteobacteria,47455@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1,Thioredoxin_4
k59_307160_1	717772.THIAE_06355	1.07e-21	91.7	COG0852@1|root,COG0852@2|Bacteria,1MX4B@1224|Proteobacteria,1S2ET@1236|Gammaproteobacteria,460NB@72273|Thiotrichales	72273|Thiotrichales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
k59_307160_3	557598.LHK_00527	9.31e-60	186.0	COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,2VSI3@28216|Betaproteobacteria,2KR3H@206351|Neisseriales	206351|Neisseriales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
k59_1776207_1	159087.Daro_0425	1.49e-57	179.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,2VSKJ@28216|Betaproteobacteria,2KWRA@206389|Rhodocyclales	206389|Rhodocyclales	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
k59_1659134_1	159087.Daro_1505	1.86e-104	314.0	COG2710@1|root,COG2710@2|Bacteria,1MWSX@1224|Proteobacteria,2VJNA@28216|Betaproteobacteria,2KV3F@206389|Rhodocyclales	206389|Rhodocyclales	C	Nitrogenase component 1 type Oxidoreductase	-	-	-	ko:K02592	-	-	-	-	ko00000	-	-	-	Oxidored_nitro
k59_307179_1	709032.Sulku_0656	1.48e-142	412.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,42MMB@68525|delta/epsilon subdivisions,2YMVM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
k59_1483667_1	159087.Daro_3330	1.52e-137	427.0	COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,2VH52@28216|Betaproteobacteria,2KUGH@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_2,DUF3971,DUF748
k59_603202_1	1165841.SULAR_08909	2.11e-90	292.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,42MWW@68525|delta/epsilon subdivisions,2YMMH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_487095_1	717231.Flexsi_0766	1.92e-09	62.8	COG0642@1|root,COG0715@1|root,COG0784@1|root,COG2198@1|root,COG2202@1|root,COG3829@1|root,COG0715@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,2GF9Q@200930|Deferribacteres	200930|Deferribacteres	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_4,Response_reg
k59_487095_2	269799.Gmet_1218	1.14e-75	258.0	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42NFR@68525|delta/epsilon subdivisions,2X7KX@28221|Deltaproteobacteria,43T3C@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_4
k59_777095_2	497321.C664_01115	2.05e-55	177.0	2C1PC@1|root,32WR4@2|Bacteria,1N4M7@1224|Proteobacteria,2VYR3@28216|Betaproteobacteria,2KYYT@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_777095_3	580332.Slit_0189	3.38e-40	136.0	COG3423@1|root,COG3423@2|Bacteria,1N8W7@1224|Proteobacteria,2VYWV@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Winged helix-turn-helix DNA-binding	ner	-	-	ko:K07724	-	-	-	-	ko00000,ko03000	-	-	-	HTH_35
k59_1133005_1	583345.Mmol_0217	2.77e-66	208.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,2VI8C@28216|Betaproteobacteria,2KM3C@206350|Nitrosomonadales	206350|Nitrosomonadales	H	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
k59_1133005_2	1132855.KB913035_gene2629	2.75e-08	52.0	COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,2VRPJ@28216|Betaproteobacteria,2KMKT@206350|Nitrosomonadales	206350|Nitrosomonadales	T	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
k59_250390_2	1537917.JU82_06725	1.91e-102	305.0	COG0618@1|root,COG0618@2|Bacteria,1RADZ@1224|Proteobacteria,43DQA@68525|delta/epsilon subdivisions,2YT8A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	DHH family	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
k59_1305150_1	1392838.AWNM01000026_gene4511	1.69e-71	228.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,2VI6I@28216|Betaproteobacteria,3T22E@506|Alcaligenaceae	28216|Betaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817	2.3.1.179	ko:K00646,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_250394_1	709032.Sulku_1787	4.88e-100	293.0	COG0778@1|root,COG0778@2|Bacteria,1N95W@1224|Proteobacteria,42T85@68525|delta/epsilon subdivisions,2YPNS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_250394_2	709032.Sulku_1788	1.61e-18	83.6	COG1979@1|root,COG1979@2|Bacteria,1QUBJ@1224|Proteobacteria,42MPI@68525|delta/epsilon subdivisions,2YMD7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	dehydrogenase	-	-	-	ko:K08325	ko00640,map00640	-	R02528	RC00739	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
k59_546995_2	646529.Desaci_0341	1.36e-13	69.7	COG0607@1|root,COG0607@2|Bacteria,1U0PW@1239|Firmicutes,24RKU@186801|Clostridia,265FQ@186807|Peptococcaceae	186801|Clostridia	P	PFAM Rhodanese-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_896073_1	1303692.SFUL_1543	2.8e-20	95.5	COG1643@1|root,COG1643@2|Bacteria,2GMAW@201174|Actinobacteria	201174|Actinobacteria	L	ATP-dependent helicase HrpB	hrpB	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
k59_603263_2	709032.Sulku_1462	1.35e-128	376.0	COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,43BJP@68525|delta/epsilon subdivisions,2YTA6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
k59_1016615_1	929558.SMGD1_0514	1.31e-33	129.0	COG0673@1|root,COG0673@2|Bacteria,1QFVG@1224|Proteobacteria,42UT6@68525|delta/epsilon subdivisions,2YPS7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
k59_1544421_1	159087.Daro_2801	3.47e-104	328.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2VHCZ@28216|Betaproteobacteria,2KVY2@206389|Rhodocyclales	206389|Rhodocyclales	P	AcrB/AcrD/AcrF family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
k59_1600100_1	1537917.JU82_07850	7.38e-28	108.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,42KZM@68525|delta/epsilon subdivisions,2YMIC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
k59_15637_2	1249480.B649_04825	4.98e-135	414.0	COG0755@1|root,COG1333@1|root,COG0755@2|Bacteria,COG1333@2|Bacteria,1RG0A@1224|Proteobacteria,42N37@68525|delta/epsilon subdivisions,2YMXW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Cytochrome c biogenesis protein	ccsBA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
k59_664162_1	1249480.B649_00550	1.6e-172	483.0	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,42MNC@68525|delta/epsilon subdivisions,2YMUY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
k59_71676_1	1537917.JU82_03120	2.09e-93	283.0	COG0477@1|root,COG2814@2|Bacteria,1MVZI@1224|Proteobacteria,42P57@68525|delta/epsilon subdivisions,2YMGG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EGP	Major facilitator superfamily	-	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1_like
k59_134826_1	1165841.SULAR_04577	3.23e-94	281.0	COG2995@1|root,COG2995@2|Bacteria,1N2QU@1224|Proteobacteria,43BAA@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	paraquat-inducible protein A	pqiA2	-	-	ko:K03808	-	-	-	-	ko00000	-	-	-	PqiA
k59_1305185_1	1304883.KI912532_gene2846	3.91e-12	65.1	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,2VJ6C@28216|Betaproteobacteria,2KUA1@206389|Rhodocyclales	206389|Rhodocyclales	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k59_1189075_1	1537917.JU82_06180	1.04e-68	211.0	COG1846@1|root,COG1846@2|Bacteria,1N75F@1224|Proteobacteria,42VDI@68525|delta/epsilon subdivisions,2YQNX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator, MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR
k59_366177_1	1304883.KI912532_gene1579	6.94e-23	89.0	2ENZW@1|root,33GKQ@2|Bacteria,1NQCD@1224|Proteobacteria,2VXYX@28216|Betaproteobacteria,2KXJX@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_366177_2	159087.Daro_3490	2.67e-45	149.0	COG4701@1|root,COG4701@2|Bacteria,1NHRC@1224|Proteobacteria,2WB0Y@28216|Betaproteobacteria,2KX66@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
k59_71689_1	1355368.JART01000025_gene96	2.4e-10	58.9	COG1396@1|root,COG1396@2|Bacteria,1Q68X@1224|Proteobacteria,432N2@68525|delta/epsilon subdivisions,2YSQF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
k59_1016681_1	583345.Mmol_0289	2.97e-108	335.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,1MUFZ@1224|Proteobacteria,2VHUF@28216|Betaproteobacteria,2KKIF@206350|Nitrosomonadales	206350|Nitrosomonadales	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
k59_1426595_1	395494.Galf_1545	1.13e-18	90.5	COG5000@1|root,COG5001@1|root,COG5000@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4,PAS_9,SBP_bac_3
k59_547090_1	748280.NH8B_3065	2.28e-71	222.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,2VHAQ@28216|Betaproteobacteria,2KPQ6@206351|Neisseriales	206351|Neisseriales	V	Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
k59_1133146_1	1537917.JU82_04810	7.08e-134	391.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,42M2M@68525|delta/epsilon subdivisions,2YMS3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
k59_1544509_1	1121035.AUCH01000003_gene1199	1.35e-26	111.0	2DNAT@1|root,32WH7@2|Bacteria,1N2AT@1224|Proteobacteria,2VV51@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_250493_2	709032.Sulku_2329	8.68e-14	69.7	COG1013@1|root,COG1013@2|Bacteria,1MUY9@1224|Proteobacteria,42MQY@68525|delta/epsilon subdivisions,2YMWJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	pyruvate ferredoxin oxidoreductase	porB	-	1.2.7.1	ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
k59_1544521_2	709032.Sulku_2154	1.08e-59	186.0	COG1981@1|root,COG1981@2|Bacteria,1RHGS@1224|Proteobacteria,42ST2@68525|delta/epsilon subdivisions,2YPG7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	membrane	-	-	-	ko:K08973	-	-	-	-	ko00000	-	-	-	UPF0093
k59_366238_1	367737.Abu_0786	1.16e-57	191.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,42MGU@68525|delta/epsilon subdivisions,2YMB7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
k59_777255_1	1537917.JU82_08305	4.92e-160	459.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,42MK9@68525|delta/epsilon subdivisions,2YNM1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	ATPase related to phosphate starvation-inducible protein PhoH	phoH	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
k59_1860077_1	1268622.AVS7_03340	9.42e-44	157.0	COG3707@1|root,COG3707@2|Bacteria,1MXDV@1224|Proteobacteria,2VKJQ@28216|Betaproteobacteria,4ABVY@80864|Comamonadaceae	28216|Betaproteobacteria	K	ANTAR domain protein	nasR	-	-	-	-	-	-	-	-	-	-	-	ANTAR,NIT
k59_1860081_1	1304883.KI912532_gene131	2.46e-36	124.0	COG1677@1|root,COG1677@2|Bacteria,1N6RZ@1224|Proteobacteria,2VVQF@28216|Betaproteobacteria,2KWVT@206389|Rhodocyclales	206389|Rhodocyclales	N	Flagellar hook-basal body	fliE	-	-	ko:K02408	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliE
k59_1860081_2	159087.Daro_0777	2.08e-20	89.4	COG5581@1|root,COG5581@2|Bacteria,1RFI4@1224|Proteobacteria,2VS7C@28216|Betaproteobacteria,2KWST@206389|Rhodocyclales	206389|Rhodocyclales	M	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility	ycgR	-	-	-	-	-	-	-	-	-	-	-	PilZ,YcgR
k59_1676739_1	395494.Galf_0364	5.72e-117	353.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,2VHI9@28216|Betaproteobacteria,44V8P@713636|Nitrosomonadales	28216|Betaproteobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
k59_1566509_1	1249480.B649_00135	5.2e-81	241.0	2AIZZ@1|root,319I0@2|Bacteria,1Q2U7@1224|Proteobacteria,42W9A@68525|delta/epsilon subdivisions,2YQB5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1735224_1	864073.HFRIS_023561	4.09e-37	139.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,2WGFS@28216|Betaproteobacteria,4723B@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_1735224_2	1121015.N789_11370	9.75e-11	62.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,1RMGD@1236|Gammaproteobacteria,1X3IV@135614|Xanthomonadales	135614|Xanthomonadales	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_506907_1	709032.Sulku_2377	2.42e-114	344.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,42MEI@68525|delta/epsilon subdivisions,2YN3Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Asparagine synthase, glutamine-hydrolyzing	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_443190_1	159087.Daro_0296	3.77e-151	454.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2VHCZ@28216|Betaproteobacteria,2KVY9@206389|Rhodocyclales	206389|Rhodocyclales	P	AcrB/AcrD/AcrF family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
k59_569802_2	573065.Astex_3082	4.65e-41	144.0	COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,2TT67@28211|Alphaproteobacteria,2KFG5@204458|Caulobacterales	204458|Caulobacterales	C	Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
k59_623846_1	159087.Daro_2181	1.18e-143	408.0	COG3455@1|root,COG3455@2|Bacteria,1NMWP@1224|Proteobacteria,2VH4H@28216|Betaproteobacteria,2KWNT@206389|Rhodocyclales	206389|Rhodocyclales	S	Type VI secretion system protein DotU	-	-	-	ko:K11892	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	DotU
k59_1091625_1	1249480.B649_06660	1.97e-95	291.0	COG3511@1|root,COG3511@2|Bacteria,1MWVP@1224|Proteobacteria,43347@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	Phosphoesterase family	plcN	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	DUF756,Phosphoesterase
k59_29594_1	159087.Daro_0167	3.6e-67	209.0	COG5473@1|root,COG5473@2|Bacteria,1N9UJ@1224|Proteobacteria,2VRZ3@28216|Betaproteobacteria,2KX03@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1273589_1	1249480.B649_07295	1.22e-117	341.0	COG2048@1|root,COG2048@2|Bacteria,1RFWK@1224|Proteobacteria,43B86@68525|delta/epsilon subdivisions,2YT6P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Heterodisulfide reductase subunit B	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	CCG
k59_1566567_1	159087.Daro_3806	1.82e-100	305.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VHNV@28216|Betaproteobacteria,2KUXM@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.32,1.2.1.85	ko:K10217	ko00362,ko00380,ko00622,ko01100,ko01120,ko01220,map00362,map00380,map00622,map01100,map01120,map01220	M00038,M00569	R02762,R03889,R05353	RC00218,RC00254	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_1091654_1	159087.Daro_3902	1.15e-103	311.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,2VHK9@28216|Betaproteobacteria,2KUUJ@206389|Rhodocyclales	206389|Rhodocyclales	H	Aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_976994_2	411476.BACOVA_02198	3.87e-38	134.0	COG0545@1|root,COG0545@2|Bacteria,4NDW4@976|Bacteroidetes,2FNCK@200643|Bacteroidia,4AMFU@815|Bacteroidaceae	976|Bacteroidetes	G	Peptidyl-prolyl cis-trans isomerase	fklB	-	5.2.1.8	ko:K03772,ko:K03773	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
k59_320426_1	1537917.JU82_00640	3.81e-102	301.0	COG0575@1|root,COG0575@2|Bacteria,1NDQ6@1224|Proteobacteria,43DJ3@68525|delta/epsilon subdivisions,2YTJ4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
k59_729478_1	159087.Daro_4101	7.04e-92	285.0	COG0457@1|root,COG0745@1|root,COG0457@2|Bacteria,COG0745@2|Bacteria,1NNCT@1224|Proteobacteria,2VK0Z@28216|Betaproteobacteria,2KZXC@206389|Rhodocyclales	206389|Rhodocyclales	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,TPR_16
k59_1860175_1	1537917.JU82_03485	1.3e-45	155.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42Q5V@68525|delta/epsilon subdivisions,2YND0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
k59_1860175_2	1537917.JU82_03490	1.16e-65	207.0	COG3218@1|root,COG3218@2|Bacteria,1NNSH@1224|Proteobacteria,42X3M@68525|delta/epsilon subdivisions,2YQQ8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	transport system auxiliary component	-	-	-	ko:K18480	-	M00669	-	-	ko00000,ko00002,ko02000	3.A.1.27.1	-	-	ABC_trans_aux
k59_1566610_1	1236959.BAMT01000002_gene2123	6.64e-102	302.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,2VI5Q@28216|Betaproteobacteria,2KM9S@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Peptidoglycan polymerase that is essential for cell division	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
k59_623912_1	1207075.PputUW4_03904	1.49e-20	98.6	COG1216@1|root,COG1216@2|Bacteria,1MX5Z@1224|Proteobacteria,1RMDY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Glycosyl transferase, family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_tranf_2_3,Glyco_trans_1_2,Glycos_transf_2,RgpF
k59_854902_1	387093.SUN_0103	4.38e-37	139.0	COG1287@1|root,COG1287@2|Bacteria,1R8YG@1224|Proteobacteria,43BIB@68525|delta/epsilon subdivisions,2YT8Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Oligosaccharide transferase	-	-	2.4.99.18	ko:K07151	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	STT3
k59_854902_2	2880.D7FI43	3.36e-06	56.6	2E273@1|root,2S9FF@2759|Eukaryota	2759|Eukaryota	S	Glycosyl transferase family 2	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006486,GO:0006807,GO:0008150,GO:0008152,GO:0008378,GO:0008417,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016263,GO:0016740,GO:0016757,GO:0016758,GO:0019538,GO:0031127,GO:0034645,GO:0036065,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0048531,GO:0070085,GO:0071704,GO:0140096,GO:0140103,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.4.1.69	ko:K12245	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	Glycos_transf_2
k59_1678371_1	709032.Sulku_1797	3.94e-90	266.0	COG2128@1|root,COG2128@2|Bacteria,1PZ9M@1224|Proteobacteria,42PYF@68525|delta/epsilon subdivisions,2YNK8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
k59_1678371_2	709032.Sulku_1793	9.46e-18	76.3	2CHW3@1|root,32S6N@2|Bacteria,1N0I3@1224|Proteobacteria,42VYX@68525|delta/epsilon subdivisions,2YSCY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Pathogenicity locus	-	-	-	-	-	-	-	-	-	-	-	-	Cdd1
k59_801095_1	1121033.AUCF01000015_gene1505	4.97e-36	141.0	28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,2TVGJ@28211|Alphaproteobacteria,2JPR0@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_156640_1	1537917.JU82_09795	3.42e-130	384.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,42N30@68525|delta/epsilon subdivisions,2YMCR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
k59_508621_1	159087.Daro_3499	5.84e-80	247.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,2VI5Q@28216|Betaproteobacteria,2KUH4@206389|Rhodocyclales	206389|Rhodocyclales	D	Peptidoglycan polymerase that is essential for cell division	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
k59_508621_2	1123236.KB899380_gene2808	6.99e-09	55.8	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,1RMQ3@1236|Gammaproteobacteria,464K0@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0050511,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	iSFV_1184.SFV_0083,iSF_1195.SF0087,iSFxv_1172.SFxv_0091,iS_1188.S0089	Glyco_tran_28_C,Glyco_transf_28
k59_801139_1	159087.Daro_0559	1.07e-105	334.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,2VH3F@28216|Betaproteobacteria,2KUJ2@206389|Rhodocyclales	206389|Rhodocyclales	L	DNA polymerase III alpha subunit	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k59_731034_2	1123514.KB905899_gene861	1.98e-70	217.0	COG0120@1|root,COG0120@2|Bacteria,1MVGR@1224|Proteobacteria,1RNF8@1236|Gammaproteobacteria,4609I@72273|Thiotrichales	72273|Thiotrichales	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
k59_1619859_1	1537917.JU82_11885	1.33e-86	258.0	COG1451@1|root,COG1451@2|Bacteria,1RDJ9@1224|Proteobacteria,42RYN@68525|delta/epsilon subdivisions,2YP3T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Metal-dependent hydrolase	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
k59_1451071_1	709032.Sulku_1185	1.64e-128	389.0	COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,42M43@68525|delta/epsilon subdivisions,2YM8G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the aconitase IPM isomerase family	acnB	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0045333,GO:0046395,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072329,GO:0072350,GO:0097159,GO:1901363,GO:1901575	4.2.1.3,4.2.1.99	ko:K01682	ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173	R01324,R01325,R01900,R04425	RC00497,RC00498,RC00618,RC01153	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_2_N,Aconitase_B_N
k59_688481_1	1249480.B649_08960	3.68e-29	117.0	COG3746@1|root,COG3746@2|Bacteria,1MY3M@1224|Proteobacteria,42NVN@68525|delta/epsilon subdivisions,2YMH8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_444978_1	765910.MARPU_09880	4.73e-36	140.0	COG0745@1|root,COG5002@1|root,COG0745@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1RQ6G@1236|Gammaproteobacteria,1WX95@135613|Chromatiales	135613|Chromatiales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg
k59_268959_1	367737.Abu_0830	3e-78	243.0	COG2200@1|root,COG2200@2|Bacteria,1MVJY@1224|Proteobacteria,42S4U@68525|delta/epsilon subdivisions,2YTK1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	EAL domain protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL
k59_1322778_1	709032.Sulku_2228	1.24e-95	302.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,42M70@68525|delta/epsilon subdivisions,2YMJM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_1861938_1	1163617.SCD_n02017	4.05e-59	198.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2VHKJ@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k59_384092_1	760154.Sulba_1915	4.31e-23	102.0	COG0715@1|root,COG2199@1|root,COG3221@1|root,COG0715@2|Bacteria,COG3221@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,43D09@68525|delta/epsilon subdivisions,2YPBR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	PT	TIGRFAM diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,NMT1,Phosphonate-bd
k59_1322780_1	1165841.SULAR_00710	1.71e-86	284.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2YMRQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_914838_1	1121035.AUCH01000016_gene2224	2.33e-07	48.9	2DTX1@1|root,33N25@2|Bacteria,1NNNE@1224|Proteobacteria,2VYM2@28216|Betaproteobacteria,2KXGV@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF3149)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3149
k59_914838_2	159087.Daro_0770	4.62e-40	145.0	COG1157@1|root,COG1157@2|Bacteria,1MUH6@1224|Proteobacteria,2VHQ5@28216|Betaproteobacteria,2KUH3@206389|Rhodocyclales	206389|Rhodocyclales	NU	ATPase FliI YscN family	fliI	-	3.6.3.14	ko:K02412	ko02040,map02040	-	-	-	ko00000,ko00001,ko01000,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	ATP-synt_ab
k59_31047_1	187272.Mlg_2739	5.59e-60	193.0	COG1126@1|root,COG1126@2|Bacteria,1MWKQ@1224|Proteobacteria,1S5GB@1236|Gammaproteobacteria,1X0RK@135613|Chromatiales	135613|Chromatiales	P	ABC transporter	-	-	3.6.3.55	ko:K06857	ko02010,map02010	M00186	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	ABC_tran
k59_1794957_1	1249480.B649_11445	2.18e-129	377.0	COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,42M5D@68525|delta/epsilon subdivisions,2YN2D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
k59_1385787_1	1195236.CTER_2692	4.64e-24	103.0	2DNBD@1|root,32WKH@2|Bacteria,1VC8D@1239|Firmicutes,24MN0@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1385787_2	1249480.B649_09930	4.42e-77	239.0	COG1216@1|root,COG1216@2|Bacteria,1QV95@1224|Proteobacteria,42QIJ@68525|delta/epsilon subdivisions,2YQ78@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_1155978_1	1165841.SULAR_03772	8.11e-76	248.0	COG1449@1|root,COG1449@2|Bacteria,1Q9WP@1224|Proteobacteria,42M42@68525|delta/epsilon subdivisions,2YMAK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	2.4.1.25	ko:K22451	ko00500,map00500	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH57	-	DUF1925,DUF1926,Glyco_hydro_57
k59_445004_2	697282.Mettu_2107	1.2e-27	103.0	2DNNV@1|root,32YCB@2|Bacteria,1N7IN@1224|Proteobacteria,1S9V9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM CcdB protein	ccdB	-	-	ko:K19163	-	-	-	-	ko00000,ko02048	-	-	-	CcdB
k59_445004_3	1537917.JU82_09445	2.75e-50	166.0	COG0300@1|root,COG0300@2|Bacteria,1PNDU@1224|Proteobacteria,42S4T@68525|delta/epsilon subdivisions,2YPBY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_212249_1	1249480.B649_09355	4.3e-58	190.0	COG3637@1|root,COG3637@2|Bacteria,1RHUP@1224|Proteobacteria,42T5V@68525|delta/epsilon subdivisions,2YTEM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Domain of unknown function (DUF3943)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3943
k59_978886_1	1537917.JU82_07380	3.07e-42	140.0	2AIYJ@1|root,319GA@2|Bacteria,1Q2NX@1224|Proteobacteria,42W0X@68525|delta/epsilon subdivisions,2YQ6Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1322825_1	159087.Daro_0141	5.83e-49	165.0	COG0778@1|root,COG0778@2|Bacteria,1MZN8@1224|Proteobacteria,2VI8R@28216|Betaproteobacteria,2KUIF@206389|Rhodocyclales	206389|Rhodocyclales	C	Cob(II)yrinic acid a,c-diamide reductase	-	-	1.13.11.79	ko:K04719	ko00740,ko01100,map00740,map01100	-	R09083	RC00435,RC02413	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
k59_31116_1	317025.Tcr_1431	1.04e-50	165.0	COG1886@1|root,COG1886@2|Bacteria,1RGWT@1224|Proteobacteria,1S5YE@1236|Gammaproteobacteria,460RD@72273|Thiotrichales	72273|Thiotrichales	N	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation	-	-	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FliMN_C
k59_31116_2	349124.Hhal_0485	6e-17	79.3	COG3190@1|root,COG3190@2|Bacteria,1PQ37@1224|Proteobacteria,1TK5Y@1236|Gammaproteobacteria,1WZNW@135613|Chromatiales	135613|Chromatiales	N	PFAM flagellar biosynthesis protein, FliO	-	-	-	ko:K02418	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliO
k59_31116_3	90813.JQMT01000001_gene1293	9.08e-83	252.0	COG1338@1|root,COG1338@2|Bacteria,1MVBU@1224|Proteobacteria,1RMYH@1236|Gammaproteobacteria,46081@72273|Thiotrichales	72273|Thiotrichales	N	Plays a role in the flagellum-specific transport system	fliP	-	-	ko:K02419	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliP
k59_156782_2	1279019.ARQK01000049_gene68	2.34e-43	149.0	COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,1RP00@1236|Gammaproteobacteria,1WY6R@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
k59_1501758_2	1070319.CAGGBEG34_160003	1.67e-10	60.8	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,2VHVY@28216|Betaproteobacteria,1K30A@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
k59_31161_1	1504981.KO116_3698	5.31e-26	110.0	COG4974@1|root,COG4974@2|Bacteria,1R7M0@1224|Proteobacteria,1RYKU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_1156140_1	1218075.BAYA01000052_gene6861	1.11e-23	97.1	COG3040@1|root,COG3040@2|Bacteria,1RDAI@1224|Proteobacteria,2VRSU@28216|Betaproteobacteria,1K7IJ@119060|Burkholderiaceae	28216|Betaproteobacteria	M	lipocalin	blc	-	-	ko:K03098	-	-	-	-	ko00000,ko04147	-	-	-	Lipocalin_2
k59_1322943_1	709032.Sulku_0463	1.16e-58	191.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,42NBS@68525|delta/epsilon subdivisions,2YMPP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	riboflavin biosynthesis protein	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
k59_1451245_1	1286631.X805_31780	1.37e-55	187.0	COG1620@1|root,COG1620@2|Bacteria,1MV13@1224|Proteobacteria,2VHJN@28216|Betaproteobacteria,1KKGB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	L-lactate permease	lldP	-	-	ko:K00427,ko:K03303	-	-	-	-	ko00000,ko02000	2.A.14,2.A.14.1.1	-	-	Lactate_perm
k59_1451245_2	159087.Daro_1761	1.32e-59	187.0	COG0589@1|root,COG0589@2|Bacteria,1N02E@1224|Proteobacteria,2VU60@28216|Betaproteobacteria,2KX6V@206389|Rhodocyclales	206389|Rhodocyclales	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_801360_1	598659.NAMH_1131	2.83e-111	336.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,42MQD@68525|delta/epsilon subdivisions,2YNHI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0659 Sulfate permease and related	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k59_801360_2	1249480.B649_11395	1.07e-63	196.0	COG1393@1|root,COG1393@2|Bacteria,1MZ4Z@1224|Proteobacteria,42TRM@68525|delta/epsilon subdivisions,2YQ2J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1393 Arsenate reductase and related	-	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
k59_1678635_1	1537917.JU82_06730	4.28e-92	282.0	COG0739@1|root,COG0739@2|Bacteria,1NESH@1224|Proteobacteria,42MGB@68525|delta/epsilon subdivisions,2YMT7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_1322966_1	1249480.B649_02725	6.34e-64	198.0	COG1585@1|root,COG1585@2|Bacteria,1QAJG@1224|Proteobacteria,43AB2@68525|delta/epsilon subdivisions,2YQRB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	OU	Membrane protein implicated in regulation of membrane protease activity	-	-	-	ko:K07340	-	-	-	-	ko00000	-	-	-	NfeD
k59_731287_1	709032.Sulku_0131	2.4e-103	317.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,42PK7@68525|delta/epsilon subdivisions,2YMS5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Amidase	-	-	3.5.1.54	ko:K01457	ko00220,ko00791,ko01100,ko01120,map00220,map00791,map01100,map01120	-	R00005	RC02756	ko00000,ko00001,ko01000	-	-	-	Amidase
k59_1093456_1	1454004.AW11_01529	1.07e-33	129.0	COG0845@1|root,COG5569@1|root,COG0845@2|Bacteria,COG5569@2|Bacteria,1MVAS@1224|Proteobacteria,2VJXV@28216|Betaproteobacteria,1KQYK@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	M	HlyD family secretion protein	cusB	-	-	ko:K07798,ko:K15727	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1,8.A.1.2.1	-	-	CusF_Ec,HlyD_D23
k59_1093456_2	1454004.AW11_01530	1.6e-65	213.0	COG1538@1|root,COG1538@2|Bacteria,1R6S1@1224|Proteobacteria,2VMHP@28216|Betaproteobacteria,1KR2N@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	MU	Outer membrane efflux protein	cusC	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
k59_156868_1	1304883.KI912532_gene1682	3.59e-135	390.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,2VHBG@28216|Betaproteobacteria,2KV9X@206389|Rhodocyclales	206389|Rhodocyclales	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
k59_731295_2	1249480.B649_08855	3.4e-54	179.0	COG2070@1|root,COG2070@2|Bacteria,1N52W@1224|Proteobacteria,42N6F@68525|delta/epsilon subdivisions,2YMD6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	2-nitropropane dioxygenase	npd	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
k59_156870_1	1304883.KI912532_gene1527	4.66e-82	249.0	COG0730@1|root,COG0730@2|Bacteria,1R712@1224|Proteobacteria,2VIJA@28216|Betaproteobacteria,2KV6U@206389|Rhodocyclales	206389|Rhodocyclales	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k59_731307_1	1157708.KB907454_gene3101	3.05e-98	302.0	COG3203@1|root,COG3203@2|Bacteria,1MXEB@1224|Proteobacteria,2VHHF@28216|Betaproteobacteria,4AES6@80864|Comamonadaceae	28216|Betaproteobacteria	M	Protein of unknown function (DUF1302)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1302
k59_801398_3	387093.SUN_0512	1.46e-75	237.0	COG1143@1|root,COG1145@1|root,COG1143@2|Bacteria,COG1145@2|Bacteria,1N7HT@1224|Proteobacteria,42RFF@68525|delta/epsilon subdivisions,2YP9P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
k59_915055_1	1537917.JU82_08060	8.14e-131	381.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,42MDB@68525|delta/epsilon subdivisions,2YMF9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7,Pribosyltran
k59_384283_1	1165841.SULAR_05333	1.25e-32	116.0	COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,42SCQ@68525|delta/epsilon subdivisions,2YPEP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
k59_336603_1	1537917.JU82_03655	9.93e-66	216.0	COG1129@1|root,COG1129@2|Bacteria,1QTT9@1224|Proteobacteria,43BJ5@68525|delta/epsilon subdivisions,2YMNZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	ABC transporter, ATP-binding protein	-	-	-	ko:K13926	-	-	-	-	ko00000	-	-	-	ABC_tran
k59_1339146_1	1197951.I6RT34_9CAUD	3.99e-20	90.5	4QGAG@10239|Viruses,4R0KB@35237|dsDNA viruses  no RNA stage,4QUA4@28883|Caudovirales	28883|Caudovirales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1339146_2	1161935.H9D1H5_9CAUD	3.61e-29	116.0	4QCM5@10239|Viruses,4QVZY@35237|dsDNA viruses  no RNA stage,4QQFH@28883|Caudovirales,4QNDH@10744|Podoviridae	10744|Podoviridae	S	Bacteriophage head to tail connecting protein	-	GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019028,GO:0019058,GO:0019068,GO:0019072,GO:0019073,GO:0032991,GO:0044403,GO:0044419,GO:0044423,GO:0046798,GO:0051704	-	-	-	-	-	-	-	-	-	-	-
k59_225623_1	1183438.GKIL_1048	2.06e-20	84.3	COG0724@1|root,COG0724@2|Bacteria,1G7Q7@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	rbpD	-	-	-	-	-	-	-	-	-	-	-	RRM_1
k59_1222573_1	1165841.SULAR_00820	2.5e-77	239.0	COG1434@1|root,COG1434@2|Bacteria,1MVW8@1224|Proteobacteria,42SRW@68525|delta/epsilon subdivisions,2YPFX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
k59_1171072_1	1540257.JQMW01000009_gene3842	3.61e-55	192.0	COG3227@1|root,COG4733@1|root,COG3227@2|Bacteria,COG4733@2|Bacteria,1TP08@1239|Firmicutes,24CIW@186801|Clostridia,36FGG@31979|Clostridiaceae	186801|Clostridia	E	hmm pf01447	-	-	3.4.24.28,3.4.24.29	ko:K01400,ko:K01401	ko01503,ko05150,map01503,map05150	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	FTP,PPC,PepSY,Peptidase_M4,Peptidase_M4_C
k59_1808524_1	1165841.SULAR_00590	4.34e-95	290.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,42MXF@68525|delta/epsilon subdivisions,2YMJ8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Mur ligase middle domain	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
k59_1584117_1	518766.Rmar_2539	6.6e-93	281.0	COG1180@1|root,COG1180@2|Bacteria,4NJ18@976|Bacteroidetes	976|Bacteroidetes	C	radical SAM domain protein	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
k59_1289077_1	387093.SUN_2278	7.25e-40	134.0	COG0718@1|root,COG0718@2|Bacteria,1Q3T8@1224|Proteobacteria,42UGW@68525|delta/epsilon subdivisions,2YPUE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	ybaB	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
k59_1289077_2	387093.SUN_2277	9.16e-14	67.8	COG0666@1|root,COG0666@2|Bacteria,1Q2UY@1224|Proteobacteria,42WAJ@68525|delta/epsilon subdivisions,2YQKP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_4,Ank_5
k59_995221_1	1122212.AULO01000014_gene1194	1.31e-28	114.0	COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,1RPAJ@1236|Gammaproteobacteria,1XIF6@135619|Oceanospirillales	135619|Oceanospirillales	K	transcriptional regulator	oxyR	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
k59_585445_2	1249480.B649_06835	7.11e-61	189.0	COG1393@1|root,COG1393@2|Bacteria,1MZ7Z@1224|Proteobacteria,42VII@68525|delta/epsilon subdivisions,2YSA0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	ArsC
k59_932655_1	1268622.AVS7_01625	2.31e-65	226.0	COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,2VHY8@28216|Betaproteobacteria,4ABJ6@80864|Comamonadaceae	28216|Betaproteobacteria	NU	Tfp pilus assembly protein tip-associated adhesin PilY1-like protein	pilY1	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC
k59_1635461_1	1537917.JU82_02895	3.44e-141	407.0	COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,42M5D@68525|delta/epsilon subdivisions,2YN2D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
k59_398195_1	159087.Daro_1410	8.55e-73	225.0	COG1433@1|root,COG1433@2|Bacteria,1PW6J@1224|Proteobacteria,2WFJ3@28216|Betaproteobacteria,2KW3D@206389|Rhodocyclales	206389|Rhodocyclales	S	Dinitrogenase iron-molybdenum cofactor, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	DIMCO_N,Nitro_FeMo-Co
k59_398195_2	159087.Daro_1411	1.19e-28	103.0	COG1145@1|root,COG1145@2|Bacteria,1N859@1224|Proteobacteria,2VXWM@28216|Betaproteobacteria,2KZX0@206389|Rhodocyclales	206389|Rhodocyclales	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
k59_458787_1	159087.Daro_0490	3.51e-106	319.0	COG2907@1|root,COG2907@2|Bacteria,1MV4Z@1224|Proteobacteria,2VHCR@28216|Betaproteobacteria,2KVDS@206389|Rhodocyclales	206389|Rhodocyclales	S	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
k59_225646_1	266117.Rxyl_1929	2.84e-90	291.0	COG1067@1|root,COG1067@2|Bacteria,2H2TE@201174|Actinobacteria	201174|Actinobacteria	O	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
k59_815763_1	1537917.JU82_04795	3.82e-109	338.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,42MKB@68525|delta/epsilon subdivisions,2YMIZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
k59_995264_1	883081.HMPREF9698_00012	3.51e-05	48.9	COG3279@1|root,COG3279@2|Bacteria,1V14X@1239|Firmicutes,4HDIC@91061|Bacilli,27G6X@186828|Carnobacteriaceae	91061|Bacilli	T	LytTr DNA-binding domain	lytT	GO:0000156,GO:0000160,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0035556,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007	-	ko:K07705	ko02020,map02020	M00492	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
k59_995264_2	709032.Sulku_1615	4.03e-53	175.0	COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,1MXYZ@1224|Proteobacteria,42M4E@68525|delta/epsilon subdivisions,2YMY0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF1722)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
k59_458822_1	709032.Sulku_0413	1.08e-12	65.1	2AK32@1|root,31AST@2|Bacteria,1Q625@1224|Proteobacteria,4329C@68525|delta/epsilon subdivisions,2YSSW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_458822_2	1249480.B649_04840	5.2e-71	223.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,42KZM@68525|delta/epsilon subdivisions,2YMIC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
k59_1875514_1	1249480.B649_10230	3.32e-13	68.9	COG3303@1|root,COG3303@2|Bacteria,1QUJG@1224|Proteobacteria,42RGW@68525|delta/epsilon subdivisions,2YMPH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
k59_1875514_2	1249480.B649_10225	1.04e-35	121.0	2A4UE@1|root,30TFZ@2|Bacteria,1PDA5@1224|Proteobacteria,42WVN@68525|delta/epsilon subdivisions,2YQRH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1753151_1	1535422.ND16A_3042	3.27e-61	222.0	COG0642@1|root,COG4251@1|root,COG0642@2|Bacteria,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,1T1YP@1236|Gammaproteobacteria,2Q8G3@267889|Colwelliaceae	1236|Gammaproteobacteria	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,CHASE3,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3
k59_932729_1	1537917.JU82_02225	3.26e-104	310.0	2C76X@1|root,2ZM1W@2|Bacteria,1P5JD@1224|Proteobacteria,42P9T@68525|delta/epsilon subdivisions,2YMRC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1584204_1	709032.Sulku_1365	4.36e-103	310.0	COG0665@1|root,COG0665@2|Bacteria,1Q0BQ@1224|Proteobacteria,42RXA@68525|delta/epsilon subdivisions,2YP66@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	COGs COG0665 Glycine D-amino acid oxidase (deaminating)	-	-	2.1.1.61	ko:K15461	-	-	R00601,R08702	RC00003,RC00053,RC00060,RC01483	ko00000,ko01000,ko03016	-	-	-	DAO
k59_1584204_2	1537917.JU82_01295	9.63e-05	43.5	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,42M6A@68525|delta/epsilon subdivisions,2YMN6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA_synt_2f
k59_703624_1	709032.Sulku_0632	5.89e-19	83.6	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,43B2E@68525|delta/epsilon subdivisions,2YN33@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	peptidylprolyl isomerase	peb4	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
k59_640363_1	709032.Sulku_2605	2.55e-147	428.0	2C3QV@1|root,2Z7YP@2|Bacteria,1MXAM@1224|Proteobacteria,42QBG@68525|delta/epsilon subdivisions,2YNTS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
k59_1516615_1	1286106.MPL1_10432	9.16e-52	186.0	COG0715@1|root,COG0834@1|root,COG5001@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,45ZS0@72273|Thiotrichales	72273|Thiotrichales	T	Diguanylate cyclase phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,NMT1,PAS_9,SBP_bac_3
k59_283827_1	944547.ABLL_1461	1.27e-37	135.0	COG0546@1|root,COG0546@2|Bacteria,1NDKE@1224|Proteobacteria,42SW4@68525|delta/epsilon subdivisions,2YPI4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	HAD-superfamily hydrolase, subfamily IA, variant 1	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_1584212_2	643562.Daes_0859	3.53e-16	76.3	COG2105@1|root,COG2105@2|Bacteria,1NIAM@1224|Proteobacteria,43B0U@68525|delta/epsilon subdivisions,2X6EW@28221|Deltaproteobacteria,2MCMX@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Gamma-glutamyl cyclotransferase, AIG2-like	-	-	-	-	-	-	-	-	-	-	-	-	GGACT
k59_1465135_1	1122604.JONR01000017_gene4311	8.88e-13	67.8	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,1S8X2@1236|Gammaproteobacteria,1X6DJ@135614|Xanthomonadales	135614|Xanthomonadales	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
k59_1465135_2	1168067.JAGP01000001_gene2087	1.67e-91	283.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,1RP4V@1236|Gammaproteobacteria,460AE@72273|Thiotrichales	72273|Thiotrichales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_1875543_1	1249480.B649_09870	6.9e-41	154.0	COG1629@1|root,COG4771@2|Bacteria,1RKNG@1224|Proteobacteria,43DI3@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	Outer membrane protein beta-barrel family	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_1222668_1	709032.Sulku_1546	1.53e-21	92.0	2BV3K@1|root,32QGM@2|Bacteria,1Q4NH@1224|Proteobacteria,42ZI1@68525|delta/epsilon subdivisions,2YRN8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1222668_3	709032.Sulku_1544	1.96e-73	222.0	COG1393@1|root,COG1393@2|Bacteria,1MZ7Z@1224|Proteobacteria,42VII@68525|delta/epsilon subdivisions,2YSA0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	ArsC
k59_1875556_1	1502770.JQMG01000001_gene405	2.47e-104	304.0	COG2878@1|root,COG2878@2|Bacteria,1MUWU@1224|Proteobacteria,2VN5I@28216|Betaproteobacteria,2KMT4@206350|Nitrosomonadales	206350|Nitrosomonadales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4_21
k59_461605_2	1165841.SULAR_10329	9.15e-77	229.0	COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,42RDZ@68525|delta/epsilon subdivisions,2YP5I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
k59_643301_1	1276756.AUEX01000012_gene3501	1.96e-78	238.0	COG0406@1|root,COG0406@2|Bacteria,1NPC4@1224|Proteobacteria,2VQTE@28216|Betaproteobacteria,4A9S9@80864|Comamonadaceae	28216|Betaproteobacteria	G	phosphoglycerate mutase	gpmB	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
k59_1342062_1	1249480.B649_05390	1.11e-117	349.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2YNK4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
k59_173450_1	945713.IALB_2549	0.000793	48.1	COG2201@1|root,COG2201@2|Bacteria	2|Bacteria	NT	protein-glutamate methylesterase activity	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
k59_1694887_2	709032.Sulku_2455	1.35e-75	229.0	COG0590@1|root,COG0590@2|Bacteria,1RHM4@1224|Proteobacteria,42SH2@68525|delta/epsilon subdivisions,2YPPH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	FJ	CMP dCMP deaminase	-	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	MafB19-deam,dCMP_cyt_deam_1
k59_1694887_3	1537917.JU82_08905	5.47e-88	278.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2YMW5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,TarH,dCache_2,sCache_2
k59_1519759_1	709032.Sulku_0137	1.77e-64	209.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,42ND6@68525|delta/epsilon subdivisions,2YN5S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
k59_871435_2	709032.Sulku_2207	8.53e-209	584.0	COG5002@1|root,COG5002@2|Bacteria,1QZ29@1224|Proteobacteria,43CEG@68525|delta/epsilon subdivisions,2YTC2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_173471_1	90814.KL370891_gene977	7.69e-66	206.0	COG2824@1|root,COG2824@2|Bacteria,1RGUU@1224|Proteobacteria,1S60W@1236|Gammaproteobacteria,462BF@72273|Thiotrichales	72273|Thiotrichales	P	PhnA Zinc-Ribbon	-	-	-	ko:K06193	ko01120,map01120	-	-	-	ko00000	-	-	-	PhnA,PhnA_Zn_Ribbon
k59_173471_3	62928.azo0266	4.17e-12	64.3	COG3658@1|root,COG3658@2|Bacteria,1RB03@1224|Proteobacteria,2VUDN@28216|Betaproteobacteria,2KWNC@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome b/b6/petB	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
k59_339644_1	1384054.N790_12015	7.59e-17	81.6	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,1RMDU@1236|Gammaproteobacteria,1X3TF@135614|Xanthomonadales	135614|Xanthomonadales	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
k59_339644_2	1123517.JOMR01000001_gene818	1.8e-21	85.5	COG1923@1|root,COG1923@2|Bacteria,1MZM1@1224|Proteobacteria,1S8W0@1236|Gammaproteobacteria,4616D@72273|Thiotrichales	72273|Thiotrichales	J	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
k59_286976_1	1304883.KI912532_gene2054	2.89e-76	243.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2VHM6@28216|Betaproteobacteria,2KV73@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_1519791_1	160488.PP_1799	6.63e-40	141.0	COG1089@1|root,COG1089@2|Bacteria,1MUX0@1224|Proteobacteria,1RMIY@1236|Gammaproteobacteria,1YXD1@136845|Pseudomonas putida group	1236|Gammaproteobacteria	H	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
k59_1519791_2	1121939.L861_02285	1.31e-27	110.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,1RMMN@1236|Gammaproteobacteria,1XHA3@135619|Oceanospirillales	135619|Oceanospirillales	M	COG2148 Sugar transferases involved in lipopolysaccharide synthesis	wcaJ	-	2.7.8.40	ko:K03606,ko:K21303	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01005	-	-	-	Bac_transf,CoA_binding_3
k59_1519824_1	159087.Daro_0986	2.23e-40	142.0	COG0845@1|root,COG0845@2|Bacteria,1MUG6@1224|Proteobacteria,2VH7G@28216|Betaproteobacteria,2KUCC@206389|Rhodocyclales	206389|Rhodocyclales	M	COG0845 Membrane-fusion protein	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
k59_1519824_2	1304883.KI912532_gene1364	1.93e-09	57.0	COG2045@1|root,COG2045@2|Bacteria,1N3KG@1224|Proteobacteria,2VR4U@28216|Betaproteobacteria,2KWE8@206389|Rhodocyclales	206389|Rhodocyclales	H	2-phosphosulpholactate phosphatase	-	-	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
k59_1342166_1	1537917.JU82_06800	1.89e-78	237.0	COG0621@1|root,COG0621@2|Bacteria,1MUCS@1224|Proteobacteria,42MN1@68525|delta/epsilon subdivisions,2YN0D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	MiaB-like tRNA modifying enzyme	yqeV	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,UPF0004
k59_1342166_2	1249480.B649_07315	5.32e-59	199.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42NK1@68525|delta/epsilon subdivisions,2YMHN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the AAA ATPase family	ftsH1	-	-	-	-	-	-	-	-	-	-	-	AAA,Peptidase_M41
k59_1694982_1	159087.Daro_0965	5.59e-136	405.0	COG2202@1|root,COG2703@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2703@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VJGE@28216|Betaproteobacteria,2KUJN@206389|Rhodocyclales	206389|Rhodocyclales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,Hemerythrin,HisKA,PAS_4,PAS_9
k59_1109937_1	1244531.CIG1485E_1315	5.49e-102	308.0	COG1979@1|root,COG1979@2|Bacteria,1QUBJ@1224|Proteobacteria,42MPI@68525|delta/epsilon subdivisions,2YMD7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	dehydrogenase	-	-	-	ko:K08325	ko00640,map00640	-	R02528	RC00739	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
k59_1109940_1	1537917.JU82_08685	8.5e-121	355.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42NES@68525|delta/epsilon subdivisions,2YMT3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Type II secretion system	ctsF	-	-	ko:K02455,ko:K12278	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
k59_746938_1	1249480.B649_08675	1.94e-49	160.0	COG1334@1|root,COG1334@2|Bacteria,1NH9T@1224|Proteobacteria,42X2H@68525|delta/epsilon subdivisions,2YR05@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	FlaG protein	-	-	-	ko:K06603	-	-	-	-	ko00000,ko02035	-	-	-	FlaG
k59_104201_2	1249480.B649_05415	5.17e-63	214.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1144@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1144@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2YMD8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	por	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
k59_287064_1	709032.Sulku_0089	3.43e-28	110.0	COG3174@1|root,COG3174@2|Bacteria,1NDBI@1224|Proteobacteria,42QBM@68525|delta/epsilon subdivisions,2YNPT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	MgtC family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
k59_287064_2	1249480.B649_00115	9.08e-41	138.0	2BSDP@1|root,32MFN@2|Bacteria,1Q399@1224|Proteobacteria,42Y0H@68525|delta/epsilon subdivisions,2YQR2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_287071_1	1249480.B649_01515	1.18e-95	300.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,42N34@68525|delta/epsilon subdivisions,2YMFS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_C
k59_1638840_1	236097.ADG881_3093	9.73e-25	99.4	COG3584@1|root,COG3584@2|Bacteria,1MZPJ@1224|Proteobacteria,1SBH0@1236|Gammaproteobacteria,1XQAG@135619|Oceanospirillales	135619|Oceanospirillales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1109957_2	1317122.ATO12_22825	9e-27	111.0	COG2244@1|root,COG2244@2|Bacteria,4NPBG@976|Bacteroidetes,1I21I@117743|Flavobacteriia	976|Bacteroidetes	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
k59_936113_1	1123504.JQKD01000009_gene2259	0.000183	46.6	COG0583@1|root,COG0583@2|Bacteria,1MVGZ@1224|Proteobacteria,2VMXA@28216|Betaproteobacteria,4ACPC@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_936113_2	1382359.JIAL01000001_gene681	1.96e-25	104.0	COG0520@1|root,COG0520@2|Bacteria,3Y2SC@57723|Acidobacteria,2JKJX@204432|Acidobacteriia	204432|Acidobacteriia	E	Aminotransferase class-V	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
k59_818794_1	709032.Sulku_0146	9.06e-108	319.0	COG1533@1|root,COG1533@2|Bacteria,1NWJ9@1224|Proteobacteria,42P30@68525|delta/epsilon subdivisions,2YNT6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	radical SAM domain protein	-	-	4.1.99.14	ko:K03716	-	-	-	-	ko00000,ko01000	-	-	-	-
k59_173676_2	1537917.JU82_04035	9.37e-136	390.0	COG1639@1|root,COG1639@2|Bacteria,1Q1C5@1224|Proteobacteria,42T98@68525|delta/epsilon subdivisions,2YPNT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_524329_1	1304883.KI912532_gene896	2.66e-130	376.0	COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,2VIBZ@28216|Betaproteobacteria,2KUXF@206389|Rhodocyclales	206389|Rhodocyclales	GM	epimerase dehydratase	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	Epimerase,NAD_binding_10
k59_173721_1	748247.AZKH_p0249	7.04e-63	212.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4
k59_1520043_1	1537917.JU82_01295	1.48e-71	235.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,42M6A@68525|delta/epsilon subdivisions,2YMN6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA_synt_2f
k59_1639005_1	1123517.JOMR01000001_gene1640	9.28e-33	119.0	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,1S46A@1236|Gammaproteobacteria,460JE@72273|Thiotrichales	72273|Thiotrichales	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
k59_1639005_2	247639.MGP2080_15889	1.61e-53	175.0	COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,1RPK3@1236|Gammaproteobacteria,1J5S9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006515,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019538,GO:0030163,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0052689,GO:0071704,GO:0140098,GO:0140101,GO:1901564,GO:1901565,GO:1901575	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
k59_936196_1	85643.Tmz1t_1335	1.66e-43	162.0	COG5001@1|root,COG5002@1|root,COG5001@2|Bacteria,COG5002@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KV9J@206389|Rhodocyclales	206389|Rhodocyclales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_9,dCache_1
k59_1520079_1	159087.Daro_3300	1.54e-97	295.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,2VKZY@28216|Betaproteobacteria,2KVWT@206389|Rhodocyclales	206389|Rhodocyclales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
k59_1520085_1	159087.Daro_3625	1.5e-104	310.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,2VHHG@28216|Betaproteobacteria,2KUIY@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k59_173790_1	709032.Sulku_1266	1.02e-68	218.0	COG1085@1|root,COG1085@2|Bacteria,1MU3E@1224|Proteobacteria,42MP4@68525|delta/epsilon subdivisions,2YNIF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1085 Galactose-1-phosphate uridylyltransferase	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
k59_1639055_1	709032.Sulku_2068	1.48e-48	155.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,42U7E@68525|delta/epsilon subdivisions,2YPT9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
k59_1420382_1	1249480.B649_09220	1.74e-94	295.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,42M2T@68525|delta/epsilon subdivisions,2YMF5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	ATP-dependent CLP protease ATP-binding subunit	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_1420382_2	1249480.B649_09225	5.2e-59	183.0	COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,42TN3@68525|delta/epsilon subdivisions,2YPT8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
k59_421080_1	709032.Sulku_2226	1.53e-111	322.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,42SR7@68525|delta/epsilon subdivisions,2YP8T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	nucleotide-binding protein implicated in inhibition of septum formation	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
k59_1184548_2	1537917.JU82_10905	1.93e-67	224.0	COG1034@1|root,COG1034@2|Bacteria,1RCFT@1224|Proteobacteria,42NK4@68525|delta/epsilon subdivisions,2YNI6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G)	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4_10,Molybdopterin,NADH-G_4Fe-4S_3
k59_302459_1	1537917.JU82_02185	7.24e-146	419.0	COG2374@1|root,COG2374@2|Bacteria,1RCTI@1224|Proteobacteria,42Q2J@68525|delta/epsilon subdivisions,2YNG1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
k59_245415_1	582744.Msip34_1199	2.03e-48	169.0	COG3146@1|root,COG3146@2|Bacteria,1R5A3@1224|Proteobacteria,2VNZT@28216|Betaproteobacteria,2KP30@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Peptidogalycan biosysnthesis/recognition	-	-	-	-	-	-	-	-	-	-	-	-	FemAB_like
k59_421094_1	323850.Shew_1047	5.78e-129	383.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,1RMMD@1236|Gammaproteobacteria,2Q9R1@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	GO:0000166,GO:0001716,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008734,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0015922,GO:0016491,GO:0016638,GO:0016641,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044318,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b2574,iBWG_1329.BWG_2338,iECDH10B_1368.ECDH10B_2742,iECDH1ME8569_1439.ECDH1ME8569_2501,iETEC_1333.ETEC_2787,iEcDH1_1363.EcDH1_1094,iJO1366.b2574,iJR904.b2574,iLF82_1304.LF82_1433,iNRG857_1313.NRG857_12785,iY75_1357.Y75_RS13445,iYL1228.KPN_02899	FAD_binding_2,Succ_DH_flav_C
k59_185466_1	1249480.B649_08795	9.64e-83	257.0	COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,42N7I@68525|delta/epsilon subdivisions,2YMDW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase
k59_540883_1	59538.XP_005975303.1	9.1e-33	130.0	COG1450@1|root,2TBP2@2759|Eukaryota,3AEB9@33154|Opisthokonta,3BWJS@33208|Metazoa	33208|Metazoa	NU	Secretin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Secretin_N_2
k59_1712798_1	522373.Smlt0904	2.02e-170	484.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,1X48A@135614|Xanthomonadales	135614|Xanthomonadales	J	GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
k59_1420437_1	1537917.JU82_00660	5.31e-14	74.3	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,43BRF@68525|delta/epsilon subdivisions,2YNGV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	TonB dependent receptor	-	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
k59_1420437_2	1249480.B649_00325	3.08e-34	122.0	2F21N@1|root,33V0K@2|Bacteria,1NXVJ@1224|Proteobacteria,42SZ2@68525|delta/epsilon subdivisions,2YPN7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	ko:K08993	-	-	-	-	ko00000	-	-	-	-
k59_712737_1	1249480.B649_03870	1.89e-104	305.0	COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,42MAM@68525|delta/epsilon subdivisions,2YT9B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	ABC transporter	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
k59_1832119_1	580332.Slit_0314	9.72e-39	144.0	COG0515@1|root,COG0664@1|root,COG0515@2|Bacteria,COG0664@2|Bacteria,1MV1P@1224|Proteobacteria,2VIE9@28216|Betaproteobacteria	28216|Betaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,cNMP_binding
k59_11428_1	709032.Sulku_1498	3.79e-117	347.0	COG2710@1|root,COG2710@2|Bacteria,1MVY2@1224|Proteobacteria,42MMI@68525|delta/epsilon subdivisions,2YNPZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Nitrogenase protein alpha chain	-	-	1.18.6.1	ko:K02586	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_nitro
k59_481509_1	1165841.SULAR_03327	5.6e-59	194.0	COG1721@1|root,COG1721@2|Bacteria	2|Bacteria	E	protein (some members contain a von Willebrand factor type A (vWA) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k59_481509_2	688245.CtCNB1_3441	3.42e-37	137.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,2VKJJ@28216|Betaproteobacteria,4AAWU@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM ATPase associated with various cellular activities, AAA_3	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_1184605_1	1165841.SULAR_10024	1.13e-38	135.0	COG5456@1|root,COG5456@2|Bacteria	2|Bacteria	P	FixH	-	-	-	-	-	-	-	-	-	-	-	-	FixH,YtkA
k59_1184605_2	1347342.BN863_29030	1e-11	64.7	COG0635@1|root,COG0635@2|Bacteria,4NEY5@976|Bacteroidetes,1HYDQ@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
k59_540950_1	709032.Sulku_0531	5.69e-112	327.0	COG1692@1|root,COG1692@2|Bacteria,1MW12@1224|Proteobacteria,42PCG@68525|delta/epsilon subdivisions,2YN6X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	metallophosphoesterase	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
k59_772512_1	395494.Galf_1824	3.82e-97	293.0	COG1721@1|root,COG1721@2|Bacteria,1R3QD@1224|Proteobacteria,2VN9P@28216|Betaproteobacteria,44WBQ@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k59_1654365_1	929558.SMGD1_1105	1.35e-30	121.0	COG1538@1|root,COG1538@2|Bacteria,1Q5ZE@1224|Proteobacteria,42V2A@68525|delta/epsilon subdivisions,2YQ6A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	COG1538 Outer membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_1420484_1	522306.CAP2UW1_0382	2.21e-89	266.0	COG1881@1|root,COG1881@2|Bacteria,1N0Y4@1224|Proteobacteria,2VJ4C@28216|Betaproteobacteria	28216|Betaproteobacteria	S	phospholipid-binding protein	bbsI	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
k59_1359999_1	1537917.JU82_07245	3.97e-59	197.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42M01@68525|delta/epsilon subdivisions,2YMF7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	ABC transporter	msbA	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
k59_833286_1	709032.Sulku_1569	6.84e-104	309.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,42MNJ@68525|delta/epsilon subdivisions,2YMDC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
k59_1360006_1	1249480.B649_06585	5.42e-26	102.0	COG0454@1|root,COG0456@2|Bacteria,1Q9FS@1224|Proteobacteria,42YQT@68525|delta/epsilon subdivisions,2YRH5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
k59_1360006_3	1249480.B649_06575	3.04e-34	117.0	2EJKX@1|root,33DBU@2|Bacteria,1NMQF@1224|Proteobacteria,42WWP@68525|delta/epsilon subdivisions,2YQW8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Rop-like	-	-	-	-	-	-	-	-	-	-	-	-	Rop-like
k59_1184633_1	637389.Acaty_c1834	3.89e-56	181.0	2DMZH@1|root,32UK7@2|Bacteria,1NX7X@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF3800)	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_712767_1	159087.Daro_3100	9.04e-41	142.0	COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,2VJ8W@28216|Betaproteobacteria,2KV2D@206389|Rhodocyclales	206389|Rhodocyclales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_712767_2	159087.Daro_3101	4.05e-30	117.0	COG2225@1|root,COG2225@2|Bacteria,1MVEV@1224|Proteobacteria,2VJK0@28216|Betaproteobacteria,2KVUU@206389|Rhodocyclales	206389|Rhodocyclales	C	Malate synthase	-	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
k59_833298_1	709032.Sulku_2155	1.46e-90	280.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,42M3N@68525|delta/epsilon subdivisions,2YMQ3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
k59_1771610_2	1537917.JU82_03325	3.91e-69	228.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,42M09@68525|delta/epsilon subdivisions,2YMWR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
k59_1245296_1	159087.Daro_2953	2.56e-112	343.0	COG4772@1|root,COG4772@2|Bacteria,1MUIH@1224|Proteobacteria,2VP66@28216|Betaproteobacteria	28216|Betaproteobacteria	M	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_67858_1	580332.Slit_2423	7.24e-81	261.0	COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,2VHS4@28216|Betaproteobacteria,44W7Y@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
k59_481582_1	1165841.SULAR_03592	7.45e-80	260.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2YRKW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0474 Cation transport ATPase	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
k59_129156_1	1537917.JU82_03405	1.22e-110	325.0	COG0242@1|root,COG0242@2|Bacteria,1QNIH@1224|Proteobacteria,42TAD@68525|delta/epsilon subdivisions,2YPKH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	COG0242 N-formylmethionyl-tRNA deformylase	-	-	-	-	-	-	-	-	-	-	-	-	Pep_deformylase
k59_129156_2	387092.NIS_0325	1.97e-13	64.7	2E91V@1|root,30Y1X@2|Bacteria,1PJX6@1224|Proteobacteria,42XQB@68525|delta/epsilon subdivisions,2YQXZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_481601_1	159087.Daro_0376	7.99e-29	112.0	COG0683@1|root,COG0683@2|Bacteria,1MXR4@1224|Proteobacteria,2VHP9@28216|Betaproteobacteria,2KVKD@206389|Rhodocyclales	206389|Rhodocyclales	E	amino acid	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_481601_2	305700.B447_09058	6.09e-72	227.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VIF8@28216|Betaproteobacteria,2KUTW@206389|Rhodocyclales	206389|Rhodocyclales	I	Belongs to the thiolase family	-	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
k59_894686_1	871963.Desdi_2013	2.04e-17	81.6	COG0477@1|root,COG2814@2|Bacteria,1UY64@1239|Firmicutes,249MW@186801|Clostridia,2615G@186807|Peptococcaceae	186801|Clostridia	EGP	major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_894686_2	1408422.JHYF01000001_gene2736	2.07e-23	99.8	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,247MB@186801|Clostridia,36EY7@31979|Clostridiaceae	186801|Clostridia	KT	Bacterial regulatory protein, Fis family	-	-	-	ko:K06714	-	-	-	-	ko00000,ko03000	-	-	-	HTH_8,PAS,PAS_4,PAS_8,PAS_9,Sigma54_activat
k59_249143_1	1121035.AUCH01000008_gene1046	8.04e-38	129.0	2EQH0@1|root,33I30@2|Bacteria,1NJ7T@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1249649_1	159087.Daro_1048	6.37e-190	535.0	COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,2VJ1F@28216|Betaproteobacteria,2KVK4@206389|Rhodocyclales	206389|Rhodocyclales	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
k59_1657855_1	1116472.MGMO_155c00140	0.000177	44.3	COG2808@1|root,COG2808@2|Bacteria,1N1B9@1224|Proteobacteria,1S5MH@1236|Gammaproteobacteria,1XEGR@135618|Methylococcales	135618|Methylococcales	K	Transcriptional regulator	-	-	-	ko:K07734	-	-	-	-	ko00000,ko03000	-	-	-	FMN_bind_2
k59_1657855_2	41431.PCC8801_3050	3.35e-35	125.0	arCOG08935@1|root,32Z08@2|Bacteria,1GAUH@1117|Cyanobacteria,3KI73@43988|Cyanothece	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1657855_3	1134474.O59_004204	7.58e-16	72.4	COG3759@1|root,COG3759@2|Bacteria,1MZ4F@1224|Proteobacteria,1S90R@1236|Gammaproteobacteria,1FHEW@10|Cellvibrio	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1304)	-	-	-	ko:K08987	-	-	-	-	ko00000	-	-	-	DUF1304
k59_545437_1	1123517.JOMR01000001_gene121	6.72e-134	388.0	COG2267@1|root,COG2267@2|Bacteria,1QUQ9@1224|Proteobacteria,1T20W@1236|Gammaproteobacteria,463VD@72273|Thiotrichales	72273|Thiotrichales	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
k59_545437_2	296591.Bpro_3937	2.83e-11	62.4	COG0607@1|root,COG0640@1|root,COG0607@2|Bacteria,COG0640@2|Bacteria,1R71B@1224|Proteobacteria,2VI9S@28216|Betaproteobacteria,4ACDQ@80864|Comamonadaceae	28216|Betaproteobacteria	K	Bacterial regulatory protein, arsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5,Rhodanese
k59_365011_1	1165841.SULAR_09944	4.06e-156	454.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,42KZC@68525|delta/epsilon subdivisions,2YM82@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
k59_485648_1	96561.Dole_3265	1.79e-38	149.0	COG0784@1|root,COG3829@1|root,COG4191@1|root,COG0784@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2X734@28221|Deltaproteobacteria,2MIC0@213118|Desulfobacterales	28221|Deltaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
k59_1424953_1	202956.BBNL01000045_gene2579	5.96e-28	116.0	COG1596@1|root,COG1596@2|Bacteria,1QN4W@1224|Proteobacteria,1TKJ7@1236|Gammaproteobacteria,3NJ0H@468|Moraxellaceae	1236|Gammaproteobacteria	M	Polysaccharide biosynthesis/export protein	-	-	-	-	-	-	-	-	-	-	-	-	Poly_export,SLBB
k59_133292_1	1537917.JU82_11155	6.61e-33	119.0	2BTHZ@1|root,32NQF@2|Bacteria,1Q3WY@1224|Proteobacteria,42XXM@68525|delta/epsilon subdivisions,2YQUG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1304263_1	983917.RGE_22590	9.18e-46	168.0	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG4191@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2WGMB@28216|Betaproteobacteria,1KPMJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Cache domain	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Reg_prop,Response_reg,Y_Y_Y,dCache_1
k59_1836560_1	1150621.SMUL_0976	3.48e-32	132.0	COG0745@1|root,COG3437@1|root,COG0745@2|Bacteria,COG3437@2|Bacteria,1NWAF@1224|Proteobacteria,43DAK@68525|delta/epsilon subdivisions,2YTHP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,Response_reg
k59_306000_1	709032.Sulku_1928	2.93e-97	300.0	28J7E@1|root,2Z92U@2|Bacteria,1NAE1@1224|Proteobacteria,42P08@68525|delta/epsilon subdivisions,2YNTD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
k59_365047_1	1357423.S5MBP4_9CAUD	5.76e-83	267.0	4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses  no RNA stage,4QRFY@28883|Caudovirales	28883|Caudovirales	S	Ribonucleotide reductase, barrel domain	-	GO:0003674,GO:0003824,GO:0004748,GO:0008150,GO:0008152,GO:0016491,GO:0016725,GO:0016728,GO:0055114,GO:0061731	-	-	-	-	-	-	-	-	-	-	-
k59_188960_1	159087.Daro_2836	9.17e-222	617.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,2VH7C@28216|Betaproteobacteria,2KVIV@206389|Rhodocyclales	206389|Rhodocyclales	M	lipoprotein releasing system, transmembrane protein, LolC E family	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
k59_1836585_1	1165841.SULAR_06793	4.02e-100	305.0	COG0739@1|root,COG0739@2|Bacteria,1NESH@1224|Proteobacteria,42MGB@68525|delta/epsilon subdivisions,2YMT7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_1716366_1	317025.Tcr_1528	9.44e-106	321.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,1RMBG@1236|Gammaproteobacteria,45ZYV@72273|Thiotrichales	72273|Thiotrichales	J	Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control	pcnB	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C
k59_70671_1	1123326.JFBL01000018_gene2366	6.08e-16	82.8	COG0835@1|root,COG0835@2|Bacteria,1QVCF@1224|Proteobacteria,42M0F@68525|delta/epsilon subdivisions,2YNAP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	PFAM CheW domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CheW,dCache_1
k59_601967_1	349521.HCH_02561	1.51e-06	55.1	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,1RNHR@1236|Gammaproteobacteria,1XMX0@135619|Oceanospirillales	135619|Oceanospirillales	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_1249761_1	159087.Daro_0356	3.24e-76	245.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,2VHE8@28216|Betaproteobacteria,2KUCJ@206389|Rhodocyclales	206389|Rhodocyclales	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
k59_1249761_2	1304883.KI912532_gene434	1.75e-14	71.6	COG0596@1|root,COG0596@2|Bacteria,1QTWQ@1224|Proteobacteria,2WGGA@28216|Betaproteobacteria,2KZPS@206389|Rhodocyclales	206389|Rhodocyclales	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
k59_1482563_1	1537917.JU82_02060	7.22e-80	256.0	COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,42P62@68525|delta/epsilon subdivisions,2YNNE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k59_1836618_1	1165841.SULAR_01340	3.77e-42	155.0	COG2203@1|root,COG2203@2|Bacteria	2|Bacteria	T	Gaf domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,GGDEF,HATPase_c,HisKA,HisKA_7TM,PAS_4,PAS_9,Response_reg
k59_1071462_1	1172190.M947_10265	2.38e-84	266.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,42MEQ@68525|delta/epsilon subdivisions,2YMGS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	COG0058 Glucan phosphorylase	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
k59_1657957_1	291112.PAU_00829	7.14e-07	56.6	COG0642@1|root,COG3437@1|root,COG2205@2|Bacteria,COG3437@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	barA	GO:0000155,GO:0000160,GO:0000302,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009636,GO:0009927,GO:0009987,GO:0010033,GO:0010035,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042221,GO:0042493,GO:0042542,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046677,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0070887,GO:0071310,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901700	2.7.13.3	ko:K07678	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF2222,HAMP,HATPase_c,HisKA,Hpt,Response_reg
k59_365096_1	929558.SMGD1_0386	6.58e-36	140.0	COG0840@1|root,COG0840@2|Bacteria,1N5N4@1224|Proteobacteria,42RSG@68525|delta/epsilon subdivisions,2YRU6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
k59_424641_1	1249480.B649_10060	1.4e-129	390.0	COG1287@1|root,COG1287@2|Bacteria,1R481@1224|Proteobacteria,42MNZ@68525|delta/epsilon subdivisions,2YMU3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Oligosaccharyl transferase, STT3 subunit	pglB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0034645,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046872,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.4.99.18,2.4.99.19	ko:K07151,ko:K17251	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	STT3
k59_424641_2	757424.Hsero_4221	3e-05	45.1	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,2VIY4@28216|Betaproteobacteria,475H1@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Bacterial sugar transferase	-	-	-	ko:K13012	-	-	-	-	ko00000,ko01005	-	-	-	Bac_transf
k59_133413_1	1123514.KB905902_gene227	6e-132	387.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,4603T@72273|Thiotrichales	72273|Thiotrichales	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
k59_133413_2	90814.KL370892_gene2298	7.5e-98	293.0	COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,1RMNR@1236|Gammaproteobacteria,4609K@72273|Thiotrichales	72273|Thiotrichales	E	Aminotransferase class-V	-	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
k59_1775180_1	1537917.JU82_02680	7.69e-57	179.0	COG1399@1|root,COG1399@2|Bacteria	2|Bacteria	K	metal-binding, possibly nucleic acid-binding protein	yceD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
k59_1775180_2	709032.Sulku_2159	7.81e-86	253.0	COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,42RIR@68525|delta/epsilon subdivisions,2YP3Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
k59_1071495_1	1123393.KB891316_gene1283	6.5e-49	165.0	29Y2F@1|root,30JVD@2|Bacteria,1RAWX@1224|Proteobacteria,2VSM0@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1363914_1	269799.Gmet_2956	1.06e-30	122.0	COG2202@1|root,COG2203@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42NFR@68525|delta/epsilon subdivisions,2WPBU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,NMT1,PAS_4,PAS_9,PocR,SBP_bac_3,dCache_1
k59_1836684_1	1249480.B649_11640	3.47e-144	421.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,42MEM@68525|delta/epsilon subdivisions,2YMWQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
k59_715367_1	1458275.AZ34_00510	1.33e-10	58.9	COG0711@1|root,COG0711@2|Bacteria,1RHZ0@1224|Proteobacteria,2VRMS@28216|Betaproteobacteria,4ADHJ@80864|Comamonadaceae	28216|Betaproteobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
k59_715367_2	767434.Fraau_0197	3.52e-40	134.0	COG0636@1|root,32S3K@2|Bacteria,1N1NA@1224|Proteobacteria,1S9MD@1236|Gammaproteobacteria,1X7KC@135614|Xanthomonadales	135614|Xanthomonadales	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
k59_715367_3	381666.H16_A3643	1.92e-32	122.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,2VHR5@28216|Betaproteobacteria,1K3JW@119060|Burkholderiaceae	28216|Betaproteobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
k59_133457_1	929558.SMGD1_1483	2.24e-11	60.8	COG2863@1|root,COG2863@2|Bacteria,1PDTH@1224|Proteobacteria,42W2E@68525|delta/epsilon subdivisions,2YQDN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome c553	cccA	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,Cytochrome_CBB3
k59_545628_2	1165841.SULAR_10024	4.44e-19	82.0	COG5456@1|root,COG5456@2|Bacteria	2|Bacteria	P	FixH	-	-	-	-	-	-	-	-	-	-	-	-	FixH,YtkA
k59_776040_3	1230342.CTM_19104	3.97e-25	108.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,36EG9@31979|Clostridiaceae	186801|Clostridia	NT	chemotaxis	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,CHASE3,HAMP,MCPsignal,dCache_1,dCache_3
k59_1482623_1	709032.Sulku_0069	9.03e-94	276.0	COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,42SVZ@68525|delta/epsilon subdivisions,2YPE3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the UPF0234 family	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
k59_1249858_1	1173263.Syn7502_01393	1.12e-86	268.0	COG0732@1|root,COG0732@2|Bacteria,1G5M6@1117|Cyanobacteria	1117|Cyanobacteria	V	Type I restriction modification DNA specificity domain	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
k59_776049_1	1449357.JQLK01000001_gene1476	6.83e-70	218.0	COG1126@1|root,COG1126@2|Bacteria,1WI0Q@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	ABC-type polar amino acid transport system ATPase component	-	-	-	ko:K09972	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3.17,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	ABC_tran
k59_776054_2	1537917.JU82_11475	2.03e-54	184.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,42MW6@68525|delta/epsilon subdivisions,2YNJR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	potassium channel protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans,Ion_trans_2,TrkA_C,TrkA_N
k59_608711_1	1121878.AUGL01000002_gene2219	1.04e-08	65.9	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,1RMS8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	slt	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009274,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	iETEC_1333.ETEC_4747,iPC815.YPO0452	SLT,SLT_L
k59_900860_1	765911.Thivi_0413	7.36e-60	209.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG2203@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1WZVB@135613|Chromatiales	135613|Chromatiales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
k59_1193771_1	717772.THIAE_01755	9.07e-48	173.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,461Z4@72273|Thiotrichales	72273|Thiotrichales	NT	helical bimodular (HBM) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,MCPsignal
k59_608713_1	1537917.JU82_11605	9.67e-49	173.0	COG5001@1|root,COG5001@2|Bacteria,1QV5H@1224|Proteobacteria,42PV8@68525|delta/epsilon subdivisions,2YMZX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,LapD_MoxY_N
k59_1607561_1	1300005.R9RFD0_9CAUD	1.34e-83	266.0	4QF3C@10239|Viruses,4QWIA@35237|dsDNA viruses  no RNA stage,4QU4U@28883|Caudovirales,4QNNQ@10744|Podoviridae	10744|Podoviridae	S	host cell wall	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1080910_1	421072.IO89_13635	1.24e-53	173.0	COG2148@1|root,COG2148@2|Bacteria,4NF29@976|Bacteroidetes,1HWQ3@117743|Flavobacteriia,3HH6Z@358033|Chryseobacterium	976|Bacteroidetes	M	Bacterial sugar transferase	wcgN	-	2.7.8.36	ko:K15915	-	-	R10184	RC00002	ko00000,ko01000	-	-	-	Bac_transf
k59_1080910_2	709032.Sulku_2411	6.8e-41	140.0	COG0110@1|root,COG0110@2|Bacteria,1MZ7U@1224|Proteobacteria,42RVS@68525|delta/epsilon subdivisions,2YP6S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family	pglD	GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.3.1.203	ko:K15913	ko00520,map00520	-	R10099	RC00004,RC00166	ko00000,ko00001,ko01000	-	-	-	Hexapep,Hexapep_2
k59_1553999_2	1249480.B649_07400	6.51e-43	151.0	COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,42MCZ@68525|delta/epsilon subdivisions,2YNV4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	HlyD membrane-fusion protein of T1SS	-	-	-	ko:K12542	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	3.A.1.109.4,8.A.1	-	-	HlyD_3
k59_1260896_1	748247.AZKH_1830	8.52e-64	210.0	COG2308@1|root,COG2308@2|Bacteria,1P9A0@1224|Proteobacteria,2VISX@28216|Betaproteobacteria,2KU66@206389|Rhodocyclales	206389|Rhodocyclales	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_78175_1	1537917.JU82_04440	2.28e-35	132.0	COG1418@1|root,COG1418@2|Bacteria,1P7YA@1224|Proteobacteria,42KZ8@68525|delta/epsilon subdivisions,2YMQS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
k59_1847583_1	1123514.KB905901_gene147	6.41e-26	109.0	COG1538@1|root,COG1538@2|Bacteria,1R4EG@1224|Proteobacteria,1S6EB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_964294_1	1249480.B649_07455	7.57e-55	190.0	COG1315@1|root,COG1315@2|Bacteria,1R5P6@1224|Proteobacteria,42MAS@68525|delta/epsilon subdivisions,2YM7Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Flagellar Assembly Protein A	-	-	-	-	-	-	-	-	-	-	-	-	FapA
k59_964294_2	1249480.B649_07450	9.59e-102	298.0	COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,42RPS@68525|delta/epsilon subdivisions,2YP4Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
k59_313055_1	709032.Sulku_2089	3.22e-108	319.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,42MV9@68525|delta/epsilon subdivisions,2YMPG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
k59_1490928_1	1304883.KI912532_gene1969	3.88e-124	364.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,2VI8D@28216|Betaproteobacteria,2KVNI@206389|Rhodocyclales	206389|Rhodocyclales	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
k59_495464_1	1040989.AWZU01000018_gene2763	2.46e-10	58.9	COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,2UBXV@28211|Alphaproteobacteria,3JWAC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
k59_495464_2	1232410.KI421419_gene2525	4.85e-32	127.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,42N97@68525|delta/epsilon subdivisions,2WKVE@28221|Deltaproteobacteria,43S28@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	CBS domain containing protein	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
k59_1783762_1	1249480.B649_02715	1.94e-45	151.0	COG3012@1|root,COG3012@2|Bacteria,1Q5V3@1224|Proteobacteria,42UFW@68525|delta/epsilon subdivisions,2YPTX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	SEC-C motif	-	-	-	ko:K09858	-	-	-	-	ko00000	-	-	-	SEC-C
k59_1783762_2	1165841.SULAR_09174	2.43e-96	285.0	COG0791@1|root,COG0791@2|Bacteria,1N0EE@1224|Proteobacteria,42V3C@68525|delta/epsilon subdivisions,2YQCX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	NlpC/P60 family	-	-	3.4.17.13	ko:K13694,ko:K13695	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60,SPOR
k59_556875_1	1165841.SULAR_08242	1.44e-118	360.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42MCY@68525|delta/epsilon subdivisions,2YMB3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB1	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
k59_21764_1	709032.Sulku_2092	7.06e-41	154.0	COG1234@1|root,COG2203@1|root,COG2206@1|root,COG3437@1|root,COG1234@2|Bacteria,COG2203@2|Bacteria,COG2206@2|Bacteria,COG3437@2|Bacteria,1MV37@1224|Proteobacteria,42N4N@68525|delta/epsilon subdivisions,2YNBF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	cAMP phosphodiesterases class-II	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HD,HD_5,Lactamase_B_2,PDEase_II
k59_1080973_1	1123401.JHYQ01000022_gene1144	2.86e-36	136.0	COG3211@1|root,COG3211@2|Bacteria,1MU8T@1224|Proteobacteria,1RSM7@1236|Gammaproteobacteria,461T0@72273|Thiotrichales	72273|Thiotrichales	S	Bacterial protein of unknown function (DUF839)	-	-	-	-	-	-	-	-	-	-	-	-	DUF839
k59_1436429_1	1537917.JU82_04925	1.42e-140	402.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,42M2J@68525|delta/epsilon subdivisions,2YN8F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	frdB	-	1.3.5.1,1.3.5.4	ko:K00240,ko:K00245	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0191	Fer2_3,Fer4_8
k59_1373323_1	1249480.B649_07405	2.07e-67	224.0	COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,42MP9@68525|delta/epsilon subdivisions,2YMN8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Type I secretion system ATPase	-	-	-	ko:K12541	ko02010,map02010	M00330	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.109.3,3.A.1.109.4	-	-	ABC_membrane,ABC_tran
k59_257957_1	870187.Thini_4369	2.34e-67	217.0	COG0220@1|root,COG0220@2|Bacteria,1QVWK@1224|Proteobacteria,1S7J8@1236|Gammaproteobacteria,460TB@72273|Thiotrichales	72273|Thiotrichales	J	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
k59_257957_2	717772.THIAE_02945	9.43e-16	77.0	COG1291@1|root,COG1291@2|Bacteria,1R7XA@1224|Proteobacteria,1SY9W@1236|Gammaproteobacteria,4623A@72273|Thiotrichales	72273|Thiotrichales	N	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
k59_846567_2	388051.AUFE01000030_gene5119	1.26e-23	96.3	2C852@1|root,32YB2@2|Bacteria,1RH28@1224|Proteobacteria,2VSQ3@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF4136)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
k59_556914_1	1463900.JOIX01000019_gene63	8.86e-06	53.5	COG2207@1|root,COG2207@2|Bacteria,2GK7C@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
k59_1847668_2	1537917.JU82_11160	1.38e-178	511.0	COG0539@1|root,COG2183@1|root,COG0539@2|Bacteria,COG2183@2|Bacteria,1MVAV@1224|Proteobacteria,42M29@68525|delta/epsilon subdivisions,2YMBM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	ribosomal protein S1	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
k59_495521_2	990073.ATHU01000003_gene1841	2.67e-28	112.0	COG0477@1|root,COG2814@2|Bacteria,1N2NP@1224|Proteobacteria,42PHM@68525|delta/epsilon subdivisions,2YNJI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_1490992_1	1249480.B649_05790	6.19e-83	247.0	2AJSH@1|root,31AEU@2|Bacteria,1Q5GG@1224|Proteobacteria,42QZH@68525|delta/epsilon subdivisions,2YP33@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1490992_2	709032.Sulku_1362	3.97e-43	147.0	COG0791@1|root,COG0791@2|Bacteria,1N0EE@1224|Proteobacteria,42V3C@68525|delta/epsilon subdivisions,2YQCX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	NlpC/P60 family	-	-	3.4.17.13	ko:K13694,ko:K13695	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60,SPOR
k59_556957_1	1537917.JU82_05940	4.47e-103	300.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,42RN6@68525|delta/epsilon subdivisions,2YP9W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
k59_1607686_1	159087.Daro_1820	1.36e-160	462.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VKB9@28216|Betaproteobacteria,2KVQT@206389|Rhodocyclales	206389|Rhodocyclales	L	helicase superfamily c-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
k59_903501_1	1304883.KI912532_gene3078	3.05e-95	291.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,2VI4G@28216|Betaproteobacteria,2KU8G@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
k59_903501_2	159087.Daro_3072	9.55e-120	346.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,2VIME@28216|Betaproteobacteria,2KUY1@206389|Rhodocyclales	206389|Rhodocyclales	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
k59_313133_2	1165841.SULAR_10574	2.28e-52	172.0	COG2107@1|root,COG2107@2|Bacteria,1NYEA@1224|Proteobacteria,42MXB@68525|delta/epsilon subdivisions,2YMNQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
k59_1554176_2	709032.Sulku_0093	1.94e-53	182.0	2DBHN@1|root,2Z9BF@2|Bacteria,1RAC8@1224|Proteobacteria,42ZKH@68525|delta/epsilon subdivisions,2YRRW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_373102_1	1537917.JU82_00855	1.11e-121	358.0	COG0045@1|root,COG0045@2|Bacteria,1PYM0@1224|Proteobacteria,42NR1@68525|delta/epsilon subdivisions,2YMG6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the succinate malate CoA ligase beta subunit family	-	-	2.3.3.8	ko:K15231	ko00020,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00720,map01100,map01110,map01120,map01130,map01200	M00173	R00352	RC00004,RC00067	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Citrate_bind
k59_1373401_1	1249627.D779_0472	2.02e-95	314.0	COG0642@1|root,COG0784@1|root,COG0834@1|root,COG0784@2|Bacteria,COG0834@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1WVYT@135613|Chromatiales	135613|Chromatiales	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3
k59_258021_1	1537917.JU82_07675	5.21e-125	360.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,42MAG@68525|delta/epsilon subdivisions,2YM8T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the TrpC family	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
k59_1491024_2	749222.Nitsa_1257	1.61e-14	69.3	COG3630@1|root,COG3630@2|Bacteria,1NFR4@1224|Proteobacteria,42XNE@68525|delta/epsilon subdivisions,2YQSS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Oxaloacetate decarboxylase, gamma chain	oadG	-	4.1.1.3	ko:K01573	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_gamma
k59_1491024_3	1165841.SULAR_01445	1.95e-07	52.8	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2YNAB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DEAD DEAH box helicase	deaD	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
k59_1373409_1	159087.Daro_2974	4.75e-130	379.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,2VHBR@28216|Betaproteobacteria,2KV2X@206389|Rhodocyclales	206389|Rhodocyclales	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
k59_1607733_1	159087.Daro_1724	3.1e-112	331.0	COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,2VHRF@28216|Betaproteobacteria,2KUDN@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
k59_846635_1	159087.Daro_0866	4.6e-77	260.0	COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,2VHX1@28216|Betaproteobacteria,2KUPN@206389|Rhodocyclales	206389|Rhodocyclales	NU	COG3170 Tfp pilus assembly protein FimV	-	-	-	ko:K08086	-	-	-	-	ko00000	-	-	-	LysM
k59_786261_1	1249480.B649_06600	4.86e-83	270.0	COG2199@1|root,COG2200@1|root,COG3287@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,COG3287@2|Bacteria,1NQKX@1224|Proteobacteria,43DAG@68525|delta/epsilon subdivisions,2YTHK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,FIST,FIST_C,GGDEF,PAS_9
k59_1554231_1	1123400.KB904749_gene742	1.46e-87	278.0	COG1982@1|root,COG1982@2|Bacteria,1MWK4@1224|Proteobacteria,1RMVF@1236|Gammaproteobacteria,460CU@72273|Thiotrichales	72273|Thiotrichales	E	Orn/Lys/Arg decarboxylase, C-terminal domain	cadA	-	4.1.1.18,4.1.1.19	ko:K01582,ko:K01584	ko00310,ko00330,ko00960,ko01100,ko01110,map00310,map00330,map00960,map01100,map01110	M00133	R00462,R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C,OKR_DC_1_N
k59_1554238_1	1165841.SULAR_06223	8.14e-66	221.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,42N34@68525|delta/epsilon subdivisions,2YMFS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_C
k59_1554238_2	387093.SUN_1888	7.77e-15	68.9	COG0484@1|root,COG0484@2|Bacteria,1NDBS@1224|Proteobacteria,42WBN@68525|delta/epsilon subdivisions,2YQK3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
k59_78357_1	76114.ebA3429	2.86e-57	184.0	COG0410@1|root,COG0410@2|Bacteria,1MUR3@1224|Proteobacteria,2VJA0@28216|Betaproteobacteria,2KXQ7@206389|Rhodocyclales	206389|Rhodocyclales	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
k59_78357_2	395495.Lcho_1206	9.99e-10	60.1	COG0411@1|root,COG0411@2|Bacteria,1R6NR@1224|Proteobacteria,2VKT2@28216|Betaproteobacteria	28216|Betaproteobacteria	E	PFAM ABC transporter related	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
k59_1607774_1	159087.Daro_3926	2.94e-37	140.0	COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,2VHG1@28216|Betaproteobacteria,2KUK1@206389|Rhodocyclales	206389|Rhodocyclales	MU	COG1538 Outer membrane protein	tolC	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
k59_612303_1	159087.Daro_0243	5.04e-79	260.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,2VH05@28216|Betaproteobacteria,2KVJX@206389|Rhodocyclales	206389|Rhodocyclales	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
k59_1554257_1	1537917.JU82_04515	7.58e-07	49.7	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,42N81@68525|delta/epsilon subdivisions,2YMAU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
k59_1554257_2	1249480.B649_08695	5.89e-56	181.0	COG0607@1|root,COG4802@1|root,COG0607@2|Bacteria,COG4802@2|Bacteria,1QYD3@1224|Proteobacteria,42PN1@68525|delta/epsilon subdivisions,2YMYE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CP	PFAM Ferredoxin thioredoxin reductase catalytic beta chain	-	-	-	-	-	-	-	-	-	-	-	-	FeThRed_B,Rhodanese
k59_1554267_2	1165841.SULAR_10644	1.27e-66	209.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,42R1W@68525|delta/epsilon subdivisions,2YNZT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Inositol monophosphatase	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
k59_433193_1	1249480.B649_04355	7.61e-88	273.0	COG1944@1|root,COG1944@2|Bacteria,1MV7K@1224|Proteobacteria,42M8K@68525|delta/epsilon subdivisions,2YMZN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	YcaO cyclodehydratase, ATP-ad Mg2+-binding	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	YcaO
k59_1607783_1	1249480.B649_07500	2.16e-73	231.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,42NJ0@68525|delta/epsilon subdivisions,2YM9A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
k59_722055_1	395494.Galf_1942	2.13e-88	264.0	COG4974@1|root,COG4974@2|Bacteria,1R6F9@1224|Proteobacteria,2W3AX@28216|Betaproteobacteria	28216|Betaproteobacteria	L	PFAM integrase family protein	-	-	-	ko:K07357,ko:K07358	-	-	-	-	ko00000	-	-	-	Phage_integrase
k59_903602_1	709032.Sulku_0429	2.96e-46	159.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Beta_helix,Big_2,Flagellin_C,Flagellin_N,VWA,VWA_2
k59_786325_1	1211112.ALJC01000044_gene2194	7.77e-171	487.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,1RMHQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
k59_1196657_1	1454004.AW11_00612	7.79e-84	260.0	COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,2VKX2@28216|Betaproteobacteria	28216|Betaproteobacteria	M	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_1081180_1	1249480.B649_10585	4.5e-78	248.0	COG4972@1|root,COG4972@2|Bacteria,1PZTK@1224|Proteobacteria,42R44@68525|delta/epsilon subdivisions,2YP2H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Pilus assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_144085_1	159087.Daro_3659	5.43e-92	294.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,2VIJ7@28216|Betaproteobacteria,2KVBE@206389|Rhodocyclales	206389|Rhodocyclales	M	Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_C
k59_258136_1	387093.SUN_1276	4.97e-58	194.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,42MNB@68525|delta/epsilon subdivisions,2YMKW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
k59_786374_1	159087.Daro_0138	3.22e-80	246.0	COG0614@1|root,COG0614@2|Bacteria,1MWVF@1224|Proteobacteria,2VJ7T@28216|Betaproteobacteria,2KU8W@206389|Rhodocyclales	206389|Rhodocyclales	P	ABC-type Fe3 -hydroxamate transport system, periplasmic component	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
k59_258151_1	886293.Sinac_5269	7e-06	55.8	COG1538@1|root,COG1538@2|Bacteria,2IZ5D@203682|Planctomycetes	203682|Planctomycetes	MU	outer membrane efflux protein	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
k59_373258_1	709032.Sulku_1186	8.66e-79	260.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,42N4X@68525|delta/epsilon subdivisions,2YMTD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Belongs to the FtsK SpoIIIE SftA family	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
k59_373267_1	666681.M301_2730	2.33e-96	309.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHZQ@28216|Betaproteobacteria,2KM30@206350|Nitrosomonadales	206350|Nitrosomonadales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18303	-	M00642	-	-	ko00000,ko00002,ko01504,ko02000	2.A.6.2.17	-	-	ACR_tran
k59_557210_1	709032.Sulku_0665	4.31e-102	309.0	COG1807@1|root,COG1807@2|Bacteria,1Q901@1224|Proteobacteria,42MGX@68525|delta/epsilon subdivisions,2YNER@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
k59_786415_1	1249480.B649_08285	1.17e-70	214.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,42TII@68525|delta/epsilon subdivisions,2YPWF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
k59_786415_2	709032.Sulku_0761	1.08e-28	107.0	COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,42PKF@68525|delta/epsilon subdivisions,2YNC3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	MotA TolQ ExbB proton channel family	tolQ	-	-	-	-	-	-	-	-	-	-	-	MotA_ExbB
k59_1491182_1	1502770.JQMG01000001_gene448	7e-113	333.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,2VH0S@28216|Betaproteobacteria,2KKNM@206350|Nitrosomonadales	206350|Nitrosomonadales	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
k59_1261313_1	1537917.JU82_01130	1.7e-121	354.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,42M8G@68525|delta/epsilon subdivisions,2YME5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
k59_786446_1	1249480.B649_01780	1.8e-36	128.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,42S1J@68525|delta/epsilon subdivisions,2YT8I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k59_786446_2	326298.Suden_0486	1.58e-52	169.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,42V4I@68525|delta/epsilon subdivisions,2YQ1K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
k59_1491198_1	1034943.BN1094_02147	1.81e-43	157.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,1RNIN@1236|Gammaproteobacteria,1JCBR@118969|Legionellales	118969|Legionellales	D	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
k59_968754_2	1249480.B649_08170	8.07e-106	315.0	COG1546@1|root,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,42MQ4@68525|delta/epsilon subdivisions,2YMUS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA
k59_1313998_1	1165841.SULAR_10199	2.5e-77	237.0	COG1028@1|root,COG1028@2|Bacteria,1RFQT@1224|Proteobacteria,43D9I@68525|delta/epsilon subdivisions,2YP3V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.320	ko:K16216	-	-	-	-	ko00000,ko01000	-	-	-	adh_short
k59_1032028_1	709032.Sulku_2514	3.59e-98	299.0	COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,42MYF@68525|delta/epsilon subdivisions,2YMXD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Single-stranded-DNA-specific exonuclease (RecJ)	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
k59_678129_1	1246459.KB898359_gene2458	6.49e-09	59.7	COG1802@1|root,COG1802@2|Bacteria,1R6HE@1224|Proteobacteria,2U2J8@28211|Alphaproteobacteria,4BBD5@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
k59_925371_1	159087.Daro_2497	3.88e-100	303.0	COG0840@1|root,COG0840@2|Bacteria,1R5W9@1224|Proteobacteria,2VKQP@28216|Betaproteobacteria,2KVCX@206389|Rhodocyclales	206389|Rhodocyclales	NT	Chemoreceptor zinc-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CZB,MCPsignal
k59_40296_1	1165841.SULAR_03752	1.09e-108	331.0	COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,42NYT@68525|delta/epsilon subdivisions,2YNMV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
k59_40296_2	1249480.B649_05390	9.85e-66	214.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2YNK4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
k59_579614_1	1304883.KI912532_gene1582	9.11e-164	483.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,2VHDH@28216|Betaproteobacteria,2KVJC@206389|Rhodocyclales	206389|Rhodocyclales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k59_1333799_1	159087.Daro_3997	9.36e-87	258.0	COG0526@1|root,COG0526@2|Bacteria,1RI3N@1224|Proteobacteria,2VR8D@28216|Betaproteobacteria,2KW3E@206389|Rhodocyclales	206389|Rhodocyclales	CO	Periplasmic protein thiol disulfide oxidoreductase DsbE	ccmG	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	Redoxin
k59_1333799_2	159087.Daro_3996	4.45e-55	188.0	COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,2VHUE@28216|Betaproteobacteria,2KUNW@206389|Rhodocyclales	206389|Rhodocyclales	O	Cytochrome c	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
k59_1164479_2	709032.Sulku_2357	6.74e-96	290.0	COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,42MBH@68525|delta/epsilon subdivisions,2YN1J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
k59_1051651_2	1537917.JU82_05715	6.36e-89	267.0	COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,42MTN@68525|delta/epsilon subdivisions,2YNAJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
k59_925440_2	709032.Sulku_1021	1.2e-128	387.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,42MP3@68525|delta/epsilon subdivisions,2YMP3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
k59_40322_1	1537917.JU82_00175	1.47e-73	230.0	COG0642@1|root,COG2205@2|Bacteria,1RK1D@1224|Proteobacteria,42R91@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_810015_1	1304883.KI912532_gene2980	4.34e-79	248.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,2VJ4R@28216|Betaproteobacteria,2KV5W@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k59_810015_2	196367.JNFG01000029_gene8641	2.15e-09	57.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,2VJ5Q@28216|Betaproteobacteria,1K0UC@119060|Burkholderiaceae	28216|Betaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_1869833_1	396588.Tgr7_3022	4.66e-51	185.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria,1WWH1@135613|Chromatiales	135613|Chromatiales	M	TIGRFAM penicillin-binding protein, 1A	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
k59_1051663_1	1123368.AUIS01000003_gene1787	8.41e-59	202.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria,2NCC6@225057|Acidithiobacillales	1236|Gammaproteobacteria	P	Cation transport ATPase (P-type)	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
k59_1051663_2	1132855.KB913035_gene2095	1.73e-73	231.0	COG0589@1|root,COG0589@2|Bacteria,1PE08@1224|Proteobacteria,2VNHV@28216|Betaproteobacteria,2KP1H@206350|Nitrosomonadales	206350|Nitrosomonadales	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_96952_1	1304883.KI912532_gene2610	1.72e-75	231.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,2VH2K@28216|Betaproteobacteria,2KUH5@206389|Rhodocyclales	206389|Rhodocyclales	J	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
k59_1869842_1	709032.Sulku_0904	5.12e-77	247.0	COG1315@1|root,COG1315@2|Bacteria,1R5P6@1224|Proteobacteria,42MAS@68525|delta/epsilon subdivisions,2YM7Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Flagellar Assembly Protein A	-	-	-	-	-	-	-	-	-	-	-	-	FapA
k59_1164514_1	1537917.JU82_03210	1.7e-21	87.8	2BQTZ@1|root,32JQR@2|Bacteria,1Q2FB@1224|Proteobacteria,431HI@68525|delta/epsilon subdivisions,2YS7I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1164514_2	1537917.JU82_03205	8.82e-73	222.0	2AJNF@1|root,31A9U@2|Bacteria,1Q56P@1224|Proteobacteria,430NW@68525|delta/epsilon subdivisions,2YS38@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_810043_1	1502770.JQMG01000001_gene502	1.28e-45	163.0	COG3614@1|root,COG5001@1|root,COG3614@2|Bacteria,COG5001@2|Bacteria,1R134@1224|Proteobacteria,2WHZ0@28216|Betaproteobacteria	28216|Betaproteobacteria	T	CHASE	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GGDEF
k59_391425_1	709032.Sulku_1959	3.39e-48	172.0	COG3437@1|root,COG3437@2|Bacteria,1QYD6@1224|Proteobacteria,43CBH@68525|delta/epsilon subdivisions,2YTB6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	cheY-homologous receiver domain	-	-	3.1.1.61,3.5.1.44	ko:K03412,ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	Response_reg
k59_516936_1	709032.Sulku_1020	1.33e-170	481.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,42M26@68525|delta/epsilon subdivisions,2YMEG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	polyphosphate kinase	ppk2	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
k59_164351_1	709032.Sulku_1317	1.81e-109	339.0	COG0835@1|root,COG0835@2|Bacteria,1QVCF@1224|Proteobacteria,42M0F@68525|delta/epsilon subdivisions,2YNAP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	PFAM CheW domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CheW,dCache_1
k59_516944_1	1249480.B649_00580	8.98e-161	458.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,42M9X@68525|delta/epsilon subdivisions,2YMQ1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
k59_1051730_2	1249480.B649_06500	7.12e-97	284.0	COG2406@1|root,COG2406@2|Bacteria,1RE25@1224|Proteobacteria,42PJ1@68525|delta/epsilon subdivisions,2YMUJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Ferritin	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
k59_40403_1	1249480.B649_09205	2.97e-98	302.0	28J7E@1|root,2Z92U@2|Bacteria,1NAE1@1224|Proteobacteria,42P08@68525|delta/epsilon subdivisions,2YNTD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
k59_739245_1	749222.Nitsa_1749	4.53e-59	184.0	COG1144@1|root,COG1144@2|Bacteria,1NM08@1224|Proteobacteria,42SV1@68525|delta/epsilon subdivisions,2YPG8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	pyruvate ferredoxin oxidoreductase	porD	-	1.2.7.1	ko:K00171	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_10,Fer4_21
k59_739245_2	387093.SUN_0200	1.19e-109	325.0	COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2YMD8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	porA	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
k59_331384_1	1537917.JU82_05810	1.5e-156	454.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MHP@68525|delta/epsilon subdivisions,2YN92@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k59_391493_1	387093.SUN_0013	2.73e-52	169.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,42RFN@68525|delta/epsilon subdivisions,2YP6C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
k59_391493_2	387092.NIS_0165	1.51e-23	94.7	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,42MFU@68525|delta/epsilon subdivisions,2YMBZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
k59_1690860_1	1249480.B649_02740	2.47e-102	298.0	COG1183@1|root,COG1183@2|Bacteria,1MYK9@1224|Proteobacteria,42RFD@68525|delta/epsilon subdivisions,2YP9Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
k59_702092_1	159087.Daro_3120	5.07e-104	321.0	COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,2VI36@28216|Betaproteobacteria,2KVSH@206389|Rhodocyclales	206389|Rhodocyclales	C	Isocitrate dehydrogenase	icd2	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
k59_335320_1	1537917.JU82_06135	1.66e-101	303.0	COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,42P4E@68525|delta/epsilon subdivisions,2YNAC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs	truD	-	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
k59_1582608_1	1249480.B649_04355	7.97e-89	276.0	COG1944@1|root,COG1944@2|Bacteria,1MV7K@1224|Proteobacteria,42M8K@68525|delta/epsilon subdivisions,2YMZN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	YcaO cyclodehydratase, ATP-ad Mg2+-binding	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	YcaO
k59_1056043_1	1165841.SULAR_03113	5e-123	353.0	COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,42YWZ@68525|delta/epsilon subdivisions,2YRHN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	JM	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)	-	-	2.7.7.99	ko:K00992	ko00520,ko01100,map00520,map01100	-	R11025	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
k59_44118_1	387093.SUN_1837	1.09e-123	364.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,42NIG@68525|delta/epsilon subdivisions,2YMX4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	dfp	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
k59_1874013_2	1537917.JU82_10875	2.59e-87	256.0	COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,42SCR@68525|delta/epsilon subdivisions,2YP9N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
k59_1582621_1	391038.Bphy_3008	1.02e-104	311.0	COG2089@1|root,COG2089@2|Bacteria,1MWG3@1224|Proteobacteria,2VHMH@28216|Betaproteobacteria,1K8JV@119060|Burkholderiaceae	28216|Betaproteobacteria	M	NeuB family	neuB	-	2.5.1.56,2.5.1.97	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	-	R01804,R04435,R09841	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
k59_1287791_1	929558.SMGD1_1016	1.21e-33	118.0	2EHAZ@1|root,33B2U@2|Bacteria,1PA3S@1224|Proteobacteria,42X9M@68525|delta/epsilon subdivisions,2YQVA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_168721_1	556269.ACDQ01000006_gene1670	8.87e-11	62.8	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg,SnoaL_3,dCache_1
k59_168721_2	555778.Hneap_1781	6.88e-05	46.6	2E4TM@1|root,32ZMZ@2|Bacteria,1NAT5@1224|Proteobacteria,1SE3M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_814334_1	1439940.BAY1663_03272	1.52e-47	159.0	COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,1RS6U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	IV02_27905	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_814334_2	159087.Daro_1066	4.47e-22	95.5	COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,2VMRU@28216|Betaproteobacteria,2KUM1@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome C oxidase accessory protein	rdxA	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
k59_168738_1	159087.Daro_0576	2.97e-98	294.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,2VIMV@28216|Betaproteobacteria,2KV2W@206389|Rhodocyclales	206389|Rhodocyclales	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
k59_867583_1	640081.Dsui_2649	1.04e-87	283.0	COG4644@1|root,COG4644@2|Bacteria,1MUIU@1224|Proteobacteria,2VI8A@28216|Betaproteobacteria,2KXCU@206389|Rhodocyclales	206389|Rhodocyclales	L	PFAM transposase Tn3 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_Tn3,DUF4158
k59_168752_2	367737.Abu_0350	1.82e-40	147.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42PMU@68525|delta/epsilon subdivisions,2YNHE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4
k59_1169521_1	1537917.JU82_02070	3.42e-62	192.0	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,42SVI@68525|delta/epsilon subdivisions,2YP80@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
k59_584059_1	709032.Sulku_0642	4.07e-286	813.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,42MWW@68525|delta/epsilon subdivisions,2YMMH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_282227_1	537972.ABQU01000048_gene1021	0.000254	43.5	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,42M1T@68525|delta/epsilon subdivisions,2YMJ5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Cell division protein FtsI penicillin-binding protein	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
k59_1751981_1	1249480.B649_02700	3.46e-146	421.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,42M15@68525|delta/epsilon subdivisions,2YMCI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
k59_867638_1	292.DM42_1353	7.4e-41	145.0	COG0598@1|root,COG0598@2|Bacteria,1MW8W@1224|Proteobacteria,2VH2A@28216|Betaproteobacteria,1K3VH@119060|Burkholderiaceae	28216|Betaproteobacteria	P	PFAM Mg2 transporter protein CorA family protein	-	-	-	ko:K16074	-	-	-	-	ko00000,ko02000	1.A.35.4	-	-	CorA
k59_867638_2	232346.JHQL01000004_gene1591	3.61e-17	77.8	COG0778@1|root,COG0778@2|Bacteria,1MZN8@1224|Proteobacteria,1RPVA@1236|Gammaproteobacteria,1XJ7R@135619|Oceanospirillales	135619|Oceanospirillales	C	Cob(II)yrinic acid a,c-diamide reductase	bluB	-	1.13.11.79	ko:K04719	ko00740,ko01100,map00740,map01100	-	R09083	RC00435,RC02413	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
k59_994029_1	929558.SMGD1_0384	1.09e-72	229.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,42M27@68525|delta/epsilon subdivisions,2YNWH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
k59_335465_1	1163617.SCD_n00826	7.15e-15	76.6	COG0748@1|root,COG0748@2|Bacteria,1RFVC@1224|Proteobacteria,2VS07@28216|Betaproteobacteria	28216|Betaproteobacteria	P	PFAM pyridoxamine 5'-phosphate oxidase-related FMN-binding	-	-	-	ko:K07226	-	-	-	-	ko00000	-	-	-	DUF2470,Putative_PNPOx,Pyrid_oxidase_2
k59_1287904_1	387093.SUN_2158	1.79e-25	95.5	COG0227@1|root,COG0227@2|Bacteria,1PTFN@1224|Proteobacteria,42V1S@68525|delta/epsilon subdivisions,2YQAP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
k59_1287904_2	1165841.SULAR_07335	6.87e-74	231.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,42MW6@68525|delta/epsilon subdivisions,2YN0V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Potassium channel protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
k59_702272_1	720554.Clocl_3383	7.38e-57	199.0	COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,2487T@186801|Clostridia,3WG8U@541000|Ruminococcaceae	186801|Clostridia	L	ATP-dependent helicase deoxyribonuclease subunit B	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
k59_1874152_1	1502770.JQMG01000001_gene1970	1.27e-88	279.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,2VHFQ@28216|Betaproteobacteria,2KM2H@206350|Nitrosomonadales	206350|Nitrosomonadales	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
k59_867664_1	709032.Sulku_1076	8.99e-57	185.0	COG3228@1|root,COG3228@2|Bacteria,1RAHF@1224|Proteobacteria,42QKQ@68525|delta/epsilon subdivisions,2YMYQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the MtfA family	-	-	-	ko:K09933	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_M90
k59_814457_3	1165841.SULAR_09694	1.77e-28	108.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,42PQP@68525|delta/epsilon subdivisions,2YNQ7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	abc transporter atp-binding protein	ybbA	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_1634142_1	709032.Sulku_1189	1.68e-06	50.1	COG3064@1|root,COG3064@2|Bacteria,1MZUF@1224|Proteobacteria,42U5X@68525|delta/epsilon subdivisions,2YQ0H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	SprA-related family	Cj0418c	-	-	-	-	-	-	-	-	-	-	-	SprA-related
k59_1337999_1	1249480.B649_11255	1.43e-87	275.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,42MEI@68525|delta/epsilon subdivisions,2YN3Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Asparagine synthase, glutamine-hydrolyzing	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_1287938_1	1304883.KI912532_gene2576	8.21e-66	214.0	COG3103@1|root,COG3103@2|Bacteria,1MVX1@1224|Proteobacteria,2VKXR@28216|Betaproteobacteria,2KVG6@206389|Rhodocyclales	206389|Rhodocyclales	T	Sh3 type 3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1169641_1	709032.Sulku_1566	1.2e-104	311.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,42MIA@68525|delta/epsilon subdivisions,2YMH1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_639125_1	159087.Daro_3866	2.58e-110	333.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,2VHT1@28216|Betaproteobacteria,2KUXG@206389|Rhodocyclales	206389|Rhodocyclales	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
k59_1874196_1	1123514.KB905899_gene1793	6.61e-43	149.0	COG1179@1|root,COG1179@2|Bacteria,1MWXR@1224|Proteobacteria,1RMT3@1236|Gammaproteobacteria,460GS@72273|Thiotrichales	72273|Thiotrichales	H	ThiF family	-	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
k59_1515271_1	709032.Sulku_0294	9.36e-131	379.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,42MUW@68525|delta/epsilon subdivisions,2YMJW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N
k59_224854_1	631362.Thi970DRAFT_02007	1.32e-48	177.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,1WX2G@135613|Chromatiales	135613|Chromatiales	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
k59_1874227_1	1165841.SULAR_07725	7.95e-71	222.0	COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,42MF9@68525|delta/epsilon subdivisions,2YN3Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0005488,GO:0010181,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0097159,GO:0097367,GO:1901265,GO:1901363	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0663	Chorismate_synt
k59_994129_1	1537917.JU82_00695	2.44e-38	138.0	COG2334@1|root,COG2334@2|Bacteria,1MUKJ@1224|Proteobacteria,42X9G@68525|delta/epsilon subdivisions,2YQEF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	homoserine kinase type II (Protein kinase fold)	-	-	2.7.1.39	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
k59_994129_2	709032.Sulku_0030	3.18e-25	101.0	COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,42R7K@68525|delta/epsilon subdivisions,2YP16@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
k59_1634227_1	1249480.B649_01180	2.02e-92	278.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,42MMX@68525|delta/epsilon subdivisions,2YMNX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
k59_396838_1	159087.Daro_4143	7.01e-119	344.0	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,2VHWH@28216|Betaproteobacteria,2KU6Q@206389|Rhodocyclales	206389|Rhodocyclales	J	Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system	ttcA	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
k59_639190_1	1165841.SULAR_09379	1.37e-60	191.0	2AIWB@1|root,319DT@2|Bacteria,1Q2F3@1224|Proteobacteria,42VJD@68525|delta/epsilon subdivisions,2YQCE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_639190_2	1165841.SULAR_09384	4.46e-21	90.9	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,42M54@68525|delta/epsilon subdivisions,2YNPD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	COG0436 Aspartate tyrosine aromatic aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
k59_743221_1	709032.Sulku_0129	1.91e-105	335.0	COG0439@1|root,COG1984@1|root,COG2049@1|root,COG0439@2|Bacteria,COG1984@2|Bacteria,COG2049@2|Bacteria,1MU4H@1224|Proteobacteria,42P49@68525|delta/epsilon subdivisions,2YNRZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EI	Allophanate hydrolase subunit 1	-	-	6.3.4.6	ko:K01941	ko00220,ko00791,ko01100,map00220,map00791,map01100	-	R00774	RC00378	ko00000,ko00001,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,CT_A_B,CT_C_D
k59_1874273_1	326298.Suden_0751	3.56e-82	264.0	COG0726@1|root,COG1649@1|root,COG0726@2|Bacteria,COG1649@2|Bacteria,1MWR2@1224|Proteobacteria,43AG1@68525|delta/epsilon subdivisions,2YT1V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Hypothetical glycosyl hydrolase family 13	-	-	-	ko:K11931	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000	-	-	-	GHL13,Polysacc_deac_1
k59_1807470_1	709032.Sulku_0755	5.33e-26	100.0	COG0711@1|root,COG0711@2|Bacteria,1Q9TP@1224|Proteobacteria,42U87@68525|delta/epsilon subdivisions,2YPT1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
k59_1807470_2	1537917.JU82_04630	1.61e-84	253.0	COG0712@1|root,COG0712@2|Bacteria,1RFPY@1224|Proteobacteria,42SKR@68525|delta/epsilon subdivisions,2YPHX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
k59_702430_1	675806.VII_000324	1.41e-14	78.6	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1XW20@135623|Vibrionales	135623|Vibrionales	NT	COG0643 Chemotaxis protein histidine kinase and related kinases	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
k59_1241444_1	616991.JPOO01000003_gene2526	1.02e-83	264.0	COG5360@1|root,COG5360@2|Bacteria,4NHMA@976|Bacteroidetes,1I0VS@117743|Flavobacteriia	976|Bacteroidetes	S	Heparinase II/III N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III,Hepar_II_III_N
k59_1768288_1	159087.Daro_4141	4.5e-60	197.0	COG3287@1|root,COG3287@2|Bacteria,1QUQH@1224|Proteobacteria,2VMN2@28216|Betaproteobacteria,2KUGW@206389|Rhodocyclales	206389|Rhodocyclales	S	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
k59_1768288_2	1485544.JQKP01000002_gene1397	1.27e-34	129.0	COG1565@1|root,COG1565@2|Bacteria,1N3CJ@1224|Proteobacteria,2VHBE@28216|Betaproteobacteria,44V36@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
k59_1181451_1	1304883.KI912532_gene246	4.95e-56	182.0	COG0208@1|root,COG0208@2|Bacteria,1QXP8@1224|Proteobacteria,2VNUB@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	-	-	-	-	-	-	-	-	-	-	-	-	AurF
k59_1768293_1	713586.KB900536_gene112	3.91e-149	441.0	COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,1RN9V@1236|Gammaproteobacteria,1WWU3@135613|Chromatiales	135613|Chromatiales	C	UPF0313 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
k59_1768293_2	1123517.JOMR01000001_gene1711	5.56e-47	173.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,461MN@72273|Thiotrichales	72273|Thiotrichales	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal
k59_241992_1	387092.NIS_0514	9.92e-57	197.0	COG3920@1|root,COG3920@2|Bacteria,1MVPJ@1224|Proteobacteria,42PDP@68525|delta/epsilon subdivisions,2YMI8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	two-component sensor histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA_2
k59_947326_1	709032.Sulku_0919	2.11e-30	117.0	COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,42MCR@68525|delta/epsilon subdivisions,2YNV0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EK	PFAM Aminotransferase class I and II	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
k59_947326_2	709032.Sulku_0920	4.08e-158	448.0	COG2207@1|root,COG3449@1|root,COG2207@2|Bacteria,COG3449@2|Bacteria,1MWTF@1224|Proteobacteria,42PYD@68525|delta/epsilon subdivisions,2YN6I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	PFAM Bacterial transcription activator, effector binding domain	-	-	-	ko:K13652	-	-	-	-	ko00000,ko03000	-	-	-	GyrI-like,HTH_18
k59_887878_1	159087.Daro_3980	8.58e-54	180.0	COG0374@1|root,COG0374@2|Bacteria,1R6ND@1224|Proteobacteria,2VQXM@28216|Betaproteobacteria,2KXDB@206389|Rhodocyclales	206389|Rhodocyclales	C	Ni,Fe-hydrogenase I large subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1241512_1	1168034.FH5T_01470	1.56e-92	283.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,2FWYQ@200643|Bacteroidia	976|Bacteroidetes	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Sigma54_activat
k59_125346_1	1537917.JU82_10560	3.98e-56	194.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,42MVQ@68525|delta/epsilon subdivisions,2YMEZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CO	Thiol disulfide interchange protein	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin,Thioredoxin_2,Thioredoxin_7
k59_1416688_1	709032.Sulku_1482	1.34e-81	263.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42MS0@68525|delta/epsilon subdivisions,2YMTX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_1828562_1	159087.Daro_3828	5.39e-160	479.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,2KUC8@206389|Rhodocyclales	206389|Rhodocyclales	V	Protein export membrane protein	-	-	-	ko:K18902	-	M00698	-	-	ko00000,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_1063646_1	983920.Y88_3819	4.59e-21	88.6	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,2TR4J@28211|Alphaproteobacteria,2K0GH@204457|Sphingomonadales	204457|Sphingomonadales	C	Electron transfer flavoprotein	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
k59_1063646_2	159087.Daro_1210	1.31e-93	276.0	COG1309@1|root,COG1309@2|Bacteria,1R59A@1224|Proteobacteria,2VQA0@28216|Betaproteobacteria,2KW5N@206389|Rhodocyclales	206389|Rhodocyclales	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_1298346_1	1249627.D779_1990	2.1e-98	308.0	COG1629@1|root,COG4771@2|Bacteria,1MXY7@1224|Proteobacteria,1RSFW@1236|Gammaproteobacteria,1WX8N@135613|Chromatiales	135613|Chromatiales	P	TonB-dependent Receptor Plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_1356985_1	709032.Sulku_1128	2.46e-38	134.0	COG0483@1|root,COG0483@2|Bacteria,1Q17W@1224|Proteobacteria,42T1U@68525|delta/epsilon subdivisions,2YPGV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Inositol monophosphatase	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
k59_1356985_2	709032.Sulku_1129	1.65e-108	317.0	COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,42MAB@68525|delta/epsilon subdivisions,2YN34@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
k59_1475102_1	515635.Dtur_1473	4.79e-05	47.8	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_1181526_1	1537917.JU82_05785	5.19e-129	378.0	COG3203@1|root,COG3203@2|Bacteria,1QVBP@1224|Proteobacteria,42M72@68525|delta/epsilon subdivisions,2YNNX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	outer membrane porin, OprD family	-	-	-	-	-	-	-	-	-	-	-	-	OprD
k59_1181526_2	709032.Sulku_1833	6.28e-56	175.0	COG3162@1|root,COG3162@2|Bacteria,1MZF3@1224|Proteobacteria,42THN@68525|delta/epsilon subdivisions,2YPTV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF485
k59_1123555_1	709032.Sulku_1405	6.3e-48	172.0	COG2199@1|root,COG3706@2|Bacteria,1NFQH@1224|Proteobacteria,42S2B@68525|delta/epsilon subdivisions,2YPCT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PFAM Type IV pilus assembly PilZ	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_537250_1	1537917.JU82_01275	1.13e-132	386.0	COG0665@1|root,COG0665@2|Bacteria,1Q0BQ@1224|Proteobacteria,42RXA@68525|delta/epsilon subdivisions,2YP66@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	COGs COG0665 Glycine D-amino acid oxidase (deaminating)	-	-	2.1.1.61	ko:K15461	-	-	R00601,R08702	RC00003,RC00053,RC00060,RC01483	ko00000,ko01000,ko03016	-	-	-	DAO
k59_8833_1	1232683.ADIMK_0890	2.03e-25	102.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,1RNQK@1236|Gammaproteobacteria,466CZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	iSBO_1134.SBO_0282,ic_1306.c0493	F420_oxidored,P5CR_dimer
k59_8837_1	1165841.SULAR_09009	1.54e-34	127.0	COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,42MJ1@68525|delta/epsilon subdivisions,2YMZ8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0212	M20_dimer,Peptidase_M20
k59_358969_1	1537917.JU82_04070	3.89e-76	243.0	COG0778@1|root,COG0778@2|Bacteria,1Q0G9@1224|Proteobacteria,42QDE@68525|delta/epsilon subdivisions,2YMPN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_1063702_1	709032.Sulku_0248	2.27e-165	471.0	COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,42M8Q@68525|delta/epsilon subdivisions,2YR92@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	IG-like fold at C-terminal of FixG, putative oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
k59_887983_1	457398.HMPREF0326_01805	1.22e-14	79.3	COG0354@1|root,COG2931@1|root,COG0354@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,42PPF@68525|delta/epsilon subdivisions,2WM3K@28221|Deltaproteobacteria,2MG5Z@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1123601_1	1123367.C666_18125	6.96e-18	79.0	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,2VR7B@28216|Betaproteobacteria,2KW2Z@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
k59_1123601_2	1131553.JIBI01000004_gene358	5.51e-22	97.1	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,2VHAY@28216|Betaproteobacteria,371PW@32003|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM Peptidase M48	yggG_1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_19
k59_299847_1	395494.Galf_0771	3.85e-113	348.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VK3D@28216|Betaproteobacteria	28216|Betaproteobacteria	NT	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal,NIT
k59_1592559_1	709032.Sulku_0908	6.29e-104	313.0	COG1538@1|root,COG1538@2|Bacteria,1QWWG@1224|Proteobacteria,42PH5@68525|delta/epsilon subdivisions,2YMHH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_1828645_1	583345.Mmol_0557	4.05e-81	263.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VJSM@28216|Betaproteobacteria,2KM5C@206350|Nitrosomonadales	206350|Nitrosomonadales	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
k59_359004_1	929558.SMGD1_0680	2.2e-55	199.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,43AX5@68525|delta/epsilon subdivisions,2YT40@29547|Epsilonproteobacteria	1224|Proteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_9,Response_reg
k59_65292_1	709032.Sulku_0136	2.28e-37	129.0	COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,42R30@68525|delta/epsilon subdivisions,2YNU1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
k59_65292_2	1249480.B649_00560	3.47e-35	132.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,42ND6@68525|delta/epsilon subdivisions,2YN5S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
k59_594648_1	1211814.CAPG01000062_gene2955	0.000101	46.2	COG2905@1|root,COG2905@2|Bacteria,1TQFI@1239|Firmicutes,4HCIW@91061|Bacilli,1ZCEI@1386|Bacillus	91061|Bacilli	T	Putative nucleotidyltransferase substrate binding domain	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
k59_888010_1	879310.HMPREF9162_0690	5.37e-82	256.0	COG0535@1|root,COG0535@2|Bacteria,1V15A@1239|Firmicutes,4H5V3@909932|Negativicutes	909932|Negativicutes	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM,SPASM
k59_1298425_1	159087.Daro_2199	5.56e-84	258.0	COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,2VK2D@28216|Betaproteobacteria,2KVRU@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the GcvT family	-	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
k59_1006445_1	709032.Sulku_1739	1.53e-71	238.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2YRKW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0474 Cation transport ATPase	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
k59_888012_1	1537917.JU82_03180	1.99e-173	499.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,42MS8@68525|delta/epsilon subdivisions,2YMUQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
k59_947493_1	159087.Daro_3628	2.29e-43	150.0	COG0158@1|root,COG0158@2|Bacteria,1MW0E@1224|Proteobacteria,2VIJT@28216|Betaproteobacteria,2KVF4@206389|Rhodocyclales	206389|Rhodocyclales	G	Fructose-1-6-bisphosphatase, N-terminal domain	-	-	3.1.3.11,3.1.3.37	ko:K01086,ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R01845,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
k59_947493_2	395495.Lcho_3754	3.31e-74	231.0	COG3954@1|root,COG3954@2|Bacteria,1MWN9@1224|Proteobacteria,2VHZD@28216|Betaproteobacteria,1KIVW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Phosphoribulokinase	cbbP	-	2.7.1.19	ko:K00855	ko00710,ko01100,ko01120,ko01200,map00710,map01100,map01120,map01200	M00165,M00166	R01523	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK
k59_299868_1	159087.Daro_1583	4.47e-123	366.0	28JQB@1|root,2Z9G8@2|Bacteria,1QCH9@1224|Proteobacteria,2VJJF@28216|Betaproteobacteria,2KW13@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1768452_1	56110.Oscil6304_5015	4.68e-25	111.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,1GQAF@1117|Cyanobacteria,1HHSK@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	ko:K11959	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	GAF,HATPase_c,HisKA,PAS_9
k59_654694_2	1463917.JODC01000021_gene9139	6.4e-15	80.1	COG2267@1|root,COG2267@2|Bacteria,2I2GI@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
k59_299877_1	580332.Slit_1874	1.14e-29	114.0	COG0348@1|root,COG0348@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	-	-	-	ko:K02574	-	-	-	-	ko00000	-	-	-	Fer4_10,Fer4_18,Fer4_5,FixG_C
k59_1768457_1	1304883.KI912532_gene3006	6.28e-09	56.2	COG0604@1|root,COG0604@2|Bacteria,1MV3W@1224|Proteobacteria,2VINX@28216|Betaproteobacteria,2KU9K@206389|Rhodocyclales	206389|Rhodocyclales	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
k59_1768457_2	159087.Daro_1201	5.83e-88	261.0	COG0791@1|root,COG0791@2|Bacteria,1N0EE@1224|Proteobacteria,2VSHN@28216|Betaproteobacteria,2KWNA@206389|Rhodocyclales	206389|Rhodocyclales	M	NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
k59_537364_1	159087.Daro_1059	1.11e-81	246.0	28HPC@1|root,2Z7XD@2|Bacteria,1PQBE@1224|Proteobacteria,2W9MZ@28216|Betaproteobacteria,2KZNJ@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of unknown function (DUF4337)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4337
k59_537364_2	159087.Daro_1054	2.74e-13	68.6	COG0709@1|root,COG0709@2|Bacteria,1MWFG@1224|Proteobacteria,2VJSD@28216|Betaproteobacteria,2KUV8@206389|Rhodocyclales	206389|Rhodocyclales	F	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
k59_1592606_1	709032.Sulku_0794	1.4e-84	271.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42UBD@68525|delta/epsilon subdivisions,2YRGP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	7TM diverse intracellular signalling	-	-	-	ko:K20971	ko02025,map02025	-	-	-	ko00000,ko00001,ko01001,ko02022	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c
k59_125505_1	1249480.B649_04705	5.17e-115	366.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2YMRQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_299897_1	1537917.JU82_05280	4.06e-84	253.0	COG1971@1|root,COG1971@2|Bacteria,1NWBY@1224|Proteobacteria,42RE2@68525|delta/epsilon subdivisions,2YPGS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Probably functions as a manganese efflux pump	mntP	-	-	-	-	-	-	-	-	-	-	-	Mntp
k59_1123685_1	709032.Sulku_1561	1.13e-46	156.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,42NJE@68525|delta/epsilon subdivisions,2YM8V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
k59_1123685_2	1537917.JU82_06345	2.64e-72	222.0	COG1994@1|root,COG1994@2|Bacteria,1N531@1224|Proteobacteria,43AZN@68525|delta/epsilon subdivisions,2YP0U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
k59_125508_1	1249480.B649_04645	2.4e-19	86.3	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,42N3K@68525|delta/epsilon subdivisions,2YMK9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3,NTP_transferase
k59_125508_2	1249480.B649_04640	9.96e-93	283.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,42NIG@68525|delta/epsilon subdivisions,2YMX4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	dfp	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
k59_1651234_1	754027.HMPREF9554_02057	2.05e-13	72.0	COG0566@1|root,COG0566@2|Bacteria,2J5HI@203691|Spirochaetes	203691|Spirochaetes	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	-	ko:K03214	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
k59_1651234_2	1046714.AMRX01000006_gene2592	1.01e-41	149.0	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,4642Y@72275|Alteromonadaceae	1236|Gammaproteobacteria	Q	Tripartite ATP-independent periplasmic transporter, DctM component	gtrB	-	-	-	-	-	-	-	-	-	-	-	DctM
k59_418241_1	1249480.B649_05270	5.67e-94	298.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2YNQF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0474 Cation transport ATPase	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3,Na_H_Exchanger
k59_1709819_1	1123517.JOMR01000001_gene1660	3.07e-25	104.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,1RMPV@1236|Gammaproteobacteria,4606X@72273|Thiotrichales	72273|Thiotrichales	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN
k59_242177_1	1537917.JU82_06750	0.0	942.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,42M5Q@68525|delta/epsilon subdivisions,2YM9V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
k59_947556_1	1123393.KB891317_gene2471	3.27e-111	326.0	COG2048@1|root,COG2048@2|Bacteria,1N37J@1224|Proteobacteria,2VV9S@28216|Betaproteobacteria,1KSCV@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Cysteine-rich domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
k59_710509_1	387093.SUN_2065	7.24e-148	437.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,42M2T@68525|delta/epsilon subdivisions,2YMF5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	ATP-dependent CLP protease ATP-binding subunit	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_65354_1	929558.SMGD1_1017	6.05e-70	231.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42MV6@68525|delta/epsilon subdivisions,2YMMC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,NIT
k59_420132_1	279714.FuraDRAFT_2343	0.00051	46.2	COG3133@1|root,COG3133@2|Bacteria,1RA1D@1224|Proteobacteria,2WE8Q@28216|Betaproteobacteria,2KRU3@206351|Neisseriales	206351|Neisseriales	M	Outer membrane lipoprotein	-	-	-	ko:K06077	-	-	-	-	ko00000	-	-	-	Rick_17kDa_Anti
k59_1830880_1	709032.Sulku_2186	1.72e-86	272.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,42MNH@68525|delta/epsilon subdivisions,2YMIP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C
k59_127816_1	1537917.JU82_11095	1.4e-220	637.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2YN6Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DNA mismatch repair MutS family	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_III,MutS_V
k59_301623_1	709032.Sulku_2152	8.62e-66	201.0	COG1544@1|root,COG1544@2|Bacteria,1QNAY@1224|Proteobacteria,430WG@68525|delta/epsilon subdivisions,2YS0N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Sigma 54 modulation protein / S30EA ribosomal protein	-	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
k59_184466_1	1121937.AUHJ01000022_gene1362	4.52e-90	277.0	COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,1RPAN@1236|Gammaproteobacteria,464VS@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluC	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_10553_1	1123518.ARWI01000001_gene346	5.96e-62	206.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,1RMUG@1236|Gammaproteobacteria,45ZNE@72273|Thiotrichales	72273|Thiotrichales	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7,HflK_N
k59_10553_2	717773.Thicy_0514	3.48e-93	284.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,1RM8Z@1236|Gammaproteobacteria,460B4@72273|Thiotrichales	72273|Thiotrichales	O	HflC and HflK could regulate a protease	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
k59_10553_3	1123517.JOMR01000001_gene822	1.32e-107	329.0	COG3705@1|root,COG3705@2|Bacteria,1MWIG@1224|Proteobacteria,1RPRQ@1236|Gammaproteobacteria,4606C@72273|Thiotrichales	72273|Thiotrichales	E	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
k59_10553_4	1168067.JAGP01000001_gene949	2.33e-50	171.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,1RNEW@1236|Gammaproteobacteria,45ZQU@72273|Thiotrichales	72273|Thiotrichales	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
k59_1300544_1	1537917.JU82_02810	9.2e-96	288.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2YMY9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_1594582_1	1304883.KI912532_gene429	1.95e-88	278.0	COG0204@1|root,COG0204@2|Bacteria,1MWDY@1224|Proteobacteria,2VJ4I@28216|Betaproteobacteria,2KV3W@206389|Rhodocyclales	206389|Rhodocyclales	I	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,MFS_1
k59_67017_1	629265.PMA4326_10680	1.63e-29	124.0	COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,1RMZT@1236|Gammaproteobacteria,1Z5G2@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	T	Osmosensitive K+ channel His kinase sensor domain	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA,KdpD,Usp
k59_1537252_1	1537917.JU82_10465	1.06e-82	246.0	COG3585@1|root,COG3585@2|Bacteria	2|Bacteria	H	molybdate ion transport	-	-	3.6.3.29,3.6.3.55	ko:K02017,ko:K06857	ko02010,map02010	M00186,M00189	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.2,3.A.1.6.4,3.A.1.8	-	-	ABC_tran,TOBE
k59_1537252_2	709032.Sulku_1534	1.88e-27	106.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,42SUS@68525|delta/epsilon subdivisions,2YQB0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Sel1-like repeats.	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	NifU,Sel1
k59_712008_1	90813.JQMT01000001_gene1693	2.35e-88	273.0	COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,1RN1Y@1236|Gammaproteobacteria,45ZXR@72273|Thiotrichales	72273|Thiotrichales	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
k59_301662_1	1537917.JU82_05320	7.12e-91	282.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,42N50@68525|delta/epsilon subdivisions,2YN1V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
k59_1860219_1	1165841.SULAR_01325	3.56e-38	132.0	COG3829@1|root,COG3829@2|Bacteria,1RH32@1224|Proteobacteria,42SY8@68525|delta/epsilon subdivisions,2YPGC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	PAS sensor protein	-	-	-	-	-	-	-	-	-	-	-	-	PAS_3
k59_1860219_2	1165841.SULAR_01330	5.68e-42	139.0	2AJF0@1|root,31A1A@2|Bacteria,1Q4MS@1224|Proteobacteria,42ZG6@68525|delta/epsilon subdivisions,2YRPQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1091735_1	1249480.B649_01190	1.48e-82	248.0	COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,42RES@68525|delta/epsilon subdivisions,2YP9Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
k59_799317_1	1182590.BN5_03802	3.78e-81	265.0	COG2801@1|root,COG2801@2|Bacteria,1MVXV@1224|Proteobacteria,1RR5U@1236|Gammaproteobacteria,1YIKS@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	L	Mu DNA-binding domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_Tnp_Mu_1,Mu-transpos_C,rve
k59_154944_1	563040.Saut_2012	1.8e-71	241.0	COG3829@1|root,COG5001@1|root,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YMHP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,PAS_3,PAS_4,PAS_9
k59_977072_1	709032.Sulku_2506	1.02e-78	247.0	COG0803@1|root,COG0803@2|Bacteria,1MVW9@1224|Proteobacteria,42MBX@68525|delta/epsilon subdivisions,2YQ8H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the bacterial solute-binding protein 9 family	-	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
k59_913176_1	1537917.JU82_09855	1.9e-74	234.0	COG0475@1|root,COG0475@2|Bacteria,1R7K4@1224|Proteobacteria,42MF1@68525|delta/epsilon subdivisions,2YM86@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Na H antiporter	kefB_1	-	-	-	-	-	-	-	-	-	-	iIT341.HP1183	Na_H_Exchanger
k59_507026_1	1249480.B649_01915	3.38e-39	138.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	3.1.3.2,3.6.1.27	ko:K09474,ko:K19302	ko00550,ko00740,ko01100,ko02020,map00550,map00740,map01100,map02020	-	R00548,R05627	RC00002,RC00017	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
k59_686582_1	1304883.KI912532_gene775	3.75e-139	405.0	COG0569@1|root,COG0569@2|Bacteria,1MW8R@1224|Proteobacteria,2VIH1@28216|Betaproteobacteria,2KUYB@206389|Rhodocyclales	206389|Rhodocyclales	C	COG0569 K transport systems, NAD-binding component	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
k59_1735380_1	1123487.KB892835_gene3332	3.4e-59	195.0	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,2VJIT@28216|Betaproteobacteria,2KV7B@206389|Rhodocyclales	206389|Rhodocyclales	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19,2.6.1.22	ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_1735380_2	267608.RSc0028	1.51e-38	140.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VHGR@28216|Betaproteobacteria,1K02G@119060|Burkholderiaceae	28216|Betaproteobacteria	C	belongs to the aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_1091791_1	399549.Msed_1619	1.15e-07	55.1	COG0582@1|root,arCOG01241@2157|Archaea,2XPNW@28889|Crenarchaeota	28889|Crenarchaeota	L	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules	xerA	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase,zinc_ribbon_2
k59_570007_1	709032.Sulku_1517	2.74e-134	400.0	COG0008@1|root,COG0064@1|root,COG0008@2|Bacteria,COG0064@2|Bacteria,1MUC8@1224|Proteobacteria,42MAX@68525|delta/epsilon subdivisions,2YNBY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	PFAM tRNA synthetases class I (E and Q), catalytic domain	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	GatB_Yqey,tRNA-synt_1c,tRNA-synt_1c_C
k59_210685_1	1249480.B649_08660	7.18e-18	82.4	COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,42QG6@68525|delta/epsilon subdivisions,2YMUP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	na -driven multidrug efflux	-	-	-	-	-	-	-	-	-	-	-	-	MatE
k59_210685_2	1537917.JU82_04540	1.42e-33	118.0	2BJZK@1|root,32ECD@2|Bacteria,1QDIV@1224|Proteobacteria,433KD@68525|delta/epsilon subdivisions,2YSRX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_210685_3	709032.Sulku_0735	7.96e-58	191.0	COG0477@1|root,COG2814@2|Bacteria,1QRUM@1224|Proteobacteria,42MFJ@68525|delta/epsilon subdivisions,2YMW9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EGP	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_267655_1	999541.bgla_1g36180	4.49e-27	106.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,2VIBS@28216|Betaproteobacteria,1K3GU@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Reversible hydration of carbon dioxide	can	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Pro_CA
k59_267655_2	555778.Hneap_2350	4.21e-24	93.2	COG0607@1|root,32YCZ@2|Bacteria,1N6NN@1224|Proteobacteria	1224|Proteobacteria	P	sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
k59_1566742_1	1165841.SULAR_05713	6.11e-111	332.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,42MVX@68525|delta/epsilon subdivisions,2YMSF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	iIT341.HP1134	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_1154270_1	1348657.M622_15095	1.23e-57	194.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,2VHQI@28216|Betaproteobacteria,2KUHQ@206389|Rhodocyclales	206389|Rhodocyclales	E	aminopeptidase	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
k59_87826_1	159087.Daro_3885	2.37e-95	284.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,2VJD1@28216|Betaproteobacteria,2KUUS@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
k59_507096_2	1537917.JU82_02090	1.74e-81	245.0	COG5456@1|root,COG5456@2|Bacteria,1Q27X@1224|Proteobacteria,42V4G@68525|delta/epsilon subdivisions,2YQE8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	FixH	-	-	-	-	-	-	-	-	-	-	-	-	FixH,YtkA
k59_267677_1	1452718.JBOY01000010_gene3226	6.87e-10	63.5	COG0575@1|root,COG0575@2|Bacteria,1MWSV@1224|Proteobacteria,1RQ6M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Belongs to the CDS family	cdsA	GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iJN746.PP_1596,iSDY_1059.SDY_0191	CTP_transf_1
k59_267677_2	1123517.JOMR01000001_gene1005	2.26e-36	129.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,1RMVX@1236|Gammaproteobacteria,460AI@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
k59_1273796_1	525898.Sdel_0913	2.41e-48	176.0	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2YNJH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	His Kinase A (phospho-acceptor) domain	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	HATPase_c,HisKA,Hpt,PAS_9,Response_reg
k59_1449466_1	1165841.SULAR_04502	1.37e-64	210.0	COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,42NZ4@68525|delta/epsilon subdivisions,2YNNY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	COG2067 Long-chain fatty acid transport protein	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k59_1207048_1	159087.Daro_0470	1.61e-144	421.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,2VUP7@28216|Betaproteobacteria	28216|Betaproteobacteria	T	TIGRFAM Diguanylate cyclase	-	-	2.7.7.65	ko:K13069,ko:K21085	ko02026,map02026	-	R08057	-	ko00000,ko00001,ko01000	-	-	-	CHASE7,GGDEF,HAMP
k59_1793667_1	1537917.JU82_09755	1.55e-92	285.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42P4R@68525|delta/epsilon subdivisions,2YM92@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	DUF3365,MCPsignal
k59_1500054_2	1249480.B649_03450	4.47e-39	131.0	COG3951@1|root,COG3951@2|Bacteria,1Q5W9@1224|Proteobacteria,42UQG@68525|delta/epsilon subdivisions,2YPWJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MNO	Rod binding protein	flgJ	-	-	-	-	-	-	-	-	-	-	-	Rod-binding
k59_686684_1	90813.JQMT01000001_gene1833	5.69e-39	145.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,1RN3V@1236|Gammaproteobacteria,460P1@72273|Thiotrichales	72273|Thiotrichales	FP	Belongs to the GppA Ppx family	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
k59_570087_1	1172190.M947_01625	1.78e-23	103.0	COG0840@1|root,COG0840@2|Bacteria,1R486@1224|Proteobacteria,42Q5Y@68525|delta/epsilon subdivisions,2YNT8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	CZB,MCPsignal
k59_1321268_1	387093.SUN_0826	9.17e-73	224.0	COG0791@1|root,COG0791@2|Bacteria,1N0EE@1224|Proteobacteria,42V3C@68525|delta/epsilon subdivisions,2YQCX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	NlpC/P60 family	-	-	3.4.17.13	ko:K13694,ko:K13695	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60,SPOR
k59_1677002_1	1234364.AMSF01000071_gene1752	2.84e-33	126.0	COG0399@1|root,COG0399@2|Bacteria,1QTGA@1224|Proteobacteria,1S1EX@1236|Gammaproteobacteria,1X5GY@135614|Xanthomonadales	135614|Xanthomonadales	M	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
k59_1677002_2	1123502.AQXD01000003_gene1470	1.07e-31	120.0	COG0010@1|root,COG0010@2|Bacteria,1MY4S@1224|Proteobacteria,1S384@1236|Gammaproteobacteria,1X47S@135614|Xanthomonadales	135614|Xanthomonadales	E	Belongs to the arginase family	-	-	-	-	-	-	-	-	-	-	-	-	Arginase
k59_799507_1	159087.Daro_0190	8.6e-40	139.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,2VICZ@28216|Betaproteobacteria,2KVIC@206389|Rhodocyclales	206389|Rhodocyclales	M	Lipid A biosynthesis acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
k59_799507_2	159087.Daro_0191	6.12e-100	291.0	COG0454@1|root,COG0456@2|Bacteria,1RJDS@1224|Proteobacteria,2VSVF@28216|Betaproteobacteria,2KWMB@206389|Rhodocyclales	206389|Rhodocyclales	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
k59_570119_1	709032.Sulku_0642	5.38e-93	299.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,42MWW@68525|delta/epsilon subdivisions,2YMMH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_729624_1	1249480.B649_02770	4.42e-71	233.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42MCY@68525|delta/epsilon subdivisions,2YMB3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB1	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
k59_1273874_1	187272.Mlg_2675	8.51e-56	196.0	COG2905@1|root,COG5001@1|root,COG2905@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1X0A7@135613|Chromatiales	135613|Chromatiales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF,PAS_9
k59_443474_1	1537917.JU82_05660	1.52e-92	278.0	COG0697@1|root,COG0697@2|Bacteria,1R8RU@1224|Proteobacteria,42SDJ@68525|delta/epsilon subdivisions,2YPDW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_155172_1	709032.Sulku_1478	6.46e-156	461.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,42MMV@68525|delta/epsilon subdivisions,2YMV9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k59_1735509_1	1249480.B649_07810	1.16e-18	78.6	2AQJX@1|root,31FST@2|Bacteria,1QDI5@1224|Proteobacteria,432NI@68525|delta/epsilon subdivisions,2YSH6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_624155_1	709032.Sulku_0548	5.29e-34	120.0	COG3012@1|root,COG3012@2|Bacteria,1Q5V3@1224|Proteobacteria,42UFW@68525|delta/epsilon subdivisions,2YPTX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	SEC-C motif	-	-	-	ko:K09858	-	-	-	-	ko00000	-	-	-	SEC-C
k59_624155_2	1249480.B649_02710	2.26e-24	98.2	COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,42NWH@68525|delta/epsilon subdivisions,2YQPR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
k59_1041359_1	640081.Dsui_0400	1.04e-54	188.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,2VHGF@28216|Betaproteobacteria,2KV01@206389|Rhodocyclales	206389|Rhodocyclales	GM	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
k59_29788_1	159087.Daro_3120	9.41e-111	338.0	COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,2VI36@28216|Betaproteobacteria,2KVSH@206389|Rhodocyclales	206389|Rhodocyclales	C	Isocitrate dehydrogenase	icd2	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
k59_267768_1	1249480.B649_01005	1.99e-153	444.0	2C99Z@1|root,2Z9YV@2|Bacteria,1N0B7@1224|Proteobacteria,42P3M@68525|delta/epsilon subdivisions,2YMWY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF3373)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3373
k59_1273909_1	1249480.B649_08645	4.35e-116	341.0	COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,42MJ1@68525|delta/epsilon subdivisions,2YMZ8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0212	M20_dimer,Peptidase_M20
k59_913344_1	717773.Thicy_1411	1.03e-111	334.0	COG3425@1|root,COG3425@2|Bacteria,1MU4K@1224|Proteobacteria,1S16F@1236|Gammaproteobacteria,461P5@72273|Thiotrichales	72273|Thiotrichales	I	Hydroxymethylglutaryl-coenzyme A synthase N terminal	-	-	2.3.3.10	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	M00088,M00095	R01978	RC00004,RC00503	ko00000,ko00001,ko00002,ko01000	-	-	-	HMG_CoA_synt_C,HMG_CoA_synt_N
k59_1321339_1	709032.Sulku_1534	2.07e-18	82.8	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,42SUS@68525|delta/epsilon subdivisions,2YQB0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Sel1-like repeats.	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	NifU,Sel1
k59_1321339_2	1249480.B649_06785	8.9e-37	127.0	COG1433@1|root,COG1433@2|Bacteria,1Q859@1224|Proteobacteria,433F5@68525|delta/epsilon subdivisions,2YSQK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
k59_210854_1	563040.Saut_0386	4.01e-43	162.0	COG0784@1|root,COG2198@1|root,COG3287@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG3287@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,43BU6@68525|delta/epsilon subdivisions,2YTEC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Two-component sensor histidine kinase response regulator	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C,HATPase_c,HisKA,Response_reg
k59_729672_1	1502770.JQMG01000001_gene176	4.53e-77	239.0	COG0598@1|root,COG0598@2|Bacteria,1MX09@1224|Proteobacteria,2VHCH@28216|Betaproteobacteria,2KKEF@206350|Nitrosomonadales	206350|Nitrosomonadales	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
k59_1207167_1	709032.Sulku_2440	1e-29	116.0	COG3278@1|root,COG3278@2|Bacteria,1QAUQ@1224|Proteobacteria,42P3Q@68525|delta/epsilon subdivisions,2YNBX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the heme-copper respiratory oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	COX1
k59_1207167_2	709032.Sulku_2441	8.87e-67	208.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,43AWP@68525|delta/epsilon subdivisions,2YT3W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	COG1136 ABC-type antimicrobial peptide transport system ATPase component	-	-	-	ko:K02003,ko:K09810	ko02010,map02010	M00255,M00258	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.125	-	-	ABC_tran
k59_624196_1	709032.Sulku_1527	8.98e-44	157.0	COG0249@1|root,COG0249@2|Bacteria,1Q1X0@1224|Proteobacteria,42UKG@68525|delta/epsilon subdivisions,2YQ3M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KLT	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1273931_1	1249480.B649_11695	3.73e-166	474.0	COG1157@1|root,COG1157@2|Bacteria,1MUH6@1224|Proteobacteria,42M0K@68525|delta/epsilon subdivisions,2YMJX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	ATP synthase	fliI	-	3.6.3.14	ko:K02412	ko02040,map02040	-	-	-	ko00000,ko00001,ko01000,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	ATP-synt_ab
k59_1321354_1	709032.Sulku_1309	5.09e-30	117.0	COG0517@1|root,COG2199@1|root,COG0517@2|Bacteria,COG2199@2|Bacteria,1RGCV@1224|Proteobacteria,43DAF@68525|delta/epsilon subdivisions,2YTHJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG2199 FOG GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GGDEF
k59_977331_1	387093.SUN_0623	1.34e-82	271.0	COG0642@1|root,COG0784@1|root,COG2203@1|root,COG0784@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42ZAB@68525|delta/epsilon subdivisions,2YRK0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,Response_reg
k59_155253_1	709032.Sulku_0974	1.21e-107	323.0	COG3206@1|root,COG3206@2|Bacteria,1Q26P@1224|Proteobacteria,42V2K@68525|delta/epsilon subdivisions,2YQ9I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1677096_1	159087.Daro_3757	2.64e-60	193.0	COG0340@1|root,COG0340@2|Bacteria,1MWCC@1224|Proteobacteria,2VNXD@28216|Betaproteobacteria,2KVTP@206389|Rhodocyclales	206389|Rhodocyclales	H	Biotin/lipoate A/B protein ligase family	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB
k59_1677096_2	159087.Daro_3758	5.5e-13	67.8	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,2KV3K@206389|Rhodocyclales	206389|Rhodocyclales	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	ntrC	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_1618444_1	709032.Sulku_1049	9.67e-138	422.0	COG3829@1|root,COG5001@1|root,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YMHP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_9
k59_1618444_2	1537917.JU82_05660	2.43e-99	296.0	COG0697@1|root,COG0697@2|Bacteria,1R8RU@1224|Proteobacteria,42SDJ@68525|delta/epsilon subdivisions,2YPDW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_913392_2	159087.Daro_3945	3.96e-121	350.0	COG2042@1|root,COG3376@2|Bacteria,1MUYH@1224|Proteobacteria,2VJDC@28216|Betaproteobacteria,2KYK1@206389|Rhodocyclales	206389|Rhodocyclales	P	High-affinity nickel-transport protein	-	-	-	ko:K07241	-	-	-	-	ko00000,ko02000	2.A.52.1	-	-	NicO
k59_913394_1	358220.C380_18060	2.62e-114	329.0	2C80Q@1|root,30ICB@2|Bacteria,1N35V@1224|Proteobacteria,2VVGE@28216|Betaproteobacteria,4AHI4@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_855136_1	640081.Dsui_0642	7.59e-119	351.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,2VH57@28216|Betaproteobacteria,2KVI2@206389|Rhodocyclales	206389|Rhodocyclales	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
k59_686853_1	709032.Sulku_2476	8.47e-07	50.1	COG3437@1|root,COG4191@1|root,COG3437@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43DAR@68525|delta/epsilon subdivisions,2YTHT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HD
k59_690451_2	709032.Sulku_1435	3.9e-93	286.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,42N50@68525|delta/epsilon subdivisions,2YN1V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
k59_446894_1	1177181.T9A_00508	3.03e-132	393.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,1RMQI@1236|Gammaproteobacteria,1XHWC@135619|Oceanospirillales	135619|Oceanospirillales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_627743_1	1304883.KI912532_gene351	1.24e-94	281.0	COG0300@1|root,COG0300@2|Bacteria,1R735@1224|Proteobacteria,2VH63@28216|Betaproteobacteria,2KW32@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_510575_1	1168067.JAGP01000001_gene463	5.39e-75	239.0	COG0644@1|root,COG0644@2|Bacteria,1MZVI@1224|Proteobacteria,1RMNS@1236|Gammaproteobacteria,461GV@72273|Thiotrichales	72273|Thiotrichales	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
k59_916930_1	709032.Sulku_0823	6.06e-24	100.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,42MW6@68525|delta/epsilon subdivisions,2YNJR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	potassium channel protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans,Ion_trans_2,TrkA_C,TrkA_N
k59_916930_2	1537917.JU82_11480	1.83e-61	202.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,42M31@68525|delta/epsilon subdivisions,2YMGC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
k59_385670_1	1537917.JU82_01765	1.3e-316	871.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,42M80@68525|delta/epsilon subdivisions,2YMEN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
k59_1157828_1	398578.Daci_0131	2.28e-05	44.7	COG2076@1|root,COG2076@2|Bacteria,1RII5@1224|Proteobacteria,2VSQK@28216|Betaproteobacteria,4AENR@80864|Comamonadaceae	28216|Betaproteobacteria	P	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_214027_1	1123401.JHYQ01000015_gene1406	6.29e-118	343.0	COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,1RN7C@1236|Gammaproteobacteria,45ZUF@72273|Thiotrichales	72273|Thiotrichales	S	PFAM AAA domain (dynein-related subfamily)	-	-	-	ko:K04748	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	AAA_5,CbbQ_C
k59_1452540_1	1165841.SULAR_09469	8.59e-47	165.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2YMHD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA helicase	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_1452540_2	387093.SUN_0385	7.82e-50	167.0	COG0583@1|root,COG0583@2|Bacteria,1R8CE@1224|Proteobacteria,42PKW@68525|delta/epsilon subdivisions,2YNJK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_446938_1	159087.Daro_1996	3.62e-96	301.0	COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,2VJ9A@28216|Betaproteobacteria,2KV3Z@206389|Rhodocyclales	206389|Rhodocyclales	C	UPF0313 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
k59_214033_1	709032.Sulku_1367	8.84e-38	129.0	COG2033@1|root,COG2033@2|Bacteria,1NDWH@1224|Proteobacteria,42RSM@68525|delta/epsilon subdivisions,2YP5S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Desulfoferrodoxin ferrous iron-binding	-	-	1.15.1.2	ko:K05919	-	-	-	-	ko00000,ko01000	-	-	-	Desulfoferrodox
k59_214033_3	1537917.JU82_01305	2.09e-45	152.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,42QXV@68525|delta/epsilon subdivisions,2YNXY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
k59_803145_1	349163.Acry_2034	2.31e-67	221.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,2JPK4@204441|Rhodospirillales	204441|Rhodospirillales	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	ntrC	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_90563_1	159087.Daro_0009	8.18e-56	184.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,2VPGP@28216|Betaproteobacteria,2KU7G@206389|Rhodocyclales	206389|Rhodocyclales	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	rnfF	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
k59_90563_2	159087.Daro_0010	1.9e-23	96.7	COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,2VIZ3@28216|Betaproteobacteria,2KUJJ@206389|Rhodocyclales	206389|Rhodocyclales	H	Belongs to the prokaryotic GSH synthase family	gshB	-	6.3.2.3	ko:K01920	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00497,R10994	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	GSH-S_ATP,GSH-S_N
k59_32909_1	1165841.SULAR_07535	1.5e-110	325.0	COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,42MXH@68525|delta/epsilon subdivisions,2YMN3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	4-hydroxybenzoate	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
k59_1739428_1	887898.HMPREF0551_0315	1.51e-30	122.0	COG0116@1|root,COG0116@2|Bacteria,1MUQM@1224|Proteobacteria,2VHMY@28216|Betaproteobacteria,1K0NW@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Belongs to the methyltransferase superfamily	rlmL	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
k59_118925_1	709032.Sulku_0122	4.02e-60	199.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,42MIH@68525|delta/epsilon subdivisions,2YR84@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing EAL and modified HD-GYP domains	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
k59_530224_2	1249480.B649_05975	2.55e-28	110.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,42QFD@68525|delta/epsilon subdivisions,2YND7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	FP	Ppx GppA	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
k59_1234362_1	1249480.B649_03820	4.41e-114	338.0	COG2308@1|root,COG2308@2|Bacteria,1MUAD@1224|Proteobacteria,42MA8@68525|delta/epsilon subdivisions,2YNA8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
k59_1116621_1	159087.Daro_2179	4e-71	220.0	COG3521@1|root,COG3521@2|Bacteria,1RGNB@1224|Proteobacteria,2VS0J@28216|Betaproteobacteria,2KZ4F@206389|Rhodocyclales	206389|Rhodocyclales	S	Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113	-	-	-	ko:K11906	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS-SciN
k59_1528155_2	709032.Sulku_1664	3.94e-11	66.6	COG4753@1|root,COG4753@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	3.1.3.3,4.6.1.1	ko:K01768,ko:K07315	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	Guanylate_cyc,HATPase_c,HisKA,Pkinase,Response_reg,SpoIIE
k59_177377_1	944547.ABLL_1439	1.15e-52	179.0	COG1294@1|root,COG1294@2|Bacteria,1MURP@1224|Proteobacteria,42NHN@68525|delta/epsilon subdivisions,2YMB6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	cytochrome d ubiquinol oxidase, subunit II	cydB	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
k59_60236_2	1249480.B649_10855	1.25e-94	286.0	COG1426@1|root,COG1426@2|Bacteria,1Q33C@1224|Proteobacteria,42WQB@68525|delta/epsilon subdivisions,2YQFX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_353520_1	1537917.JU82_06750	1.76e-97	307.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,42M5Q@68525|delta/epsilon subdivisions,2YM9V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
k59_940884_1	1232683.ADIMK_1667	1.97e-30	119.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,1RP14@1236|Gammaproteobacteria,464DK@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iECOK1_1307.ECOK1_0652,iECS88_1305.ECS88_0684,iNRG857_1313.NRG857_02925,iPC815.YPO2610	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
k59_294915_1	1537917.JU82_02555	1.75e-174	497.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,42M7X@68525|delta/epsilon subdivisions,2YM91@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	GO:0003674,GO:0005488,GO:0005515,GO:0042802	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
k59_471341_1	709032.Sulku_1916	8.78e-57	184.0	COG1317@1|root,COG1317@2|Bacteria,1NJAJ@1224|Proteobacteria,42P5I@68525|delta/epsilon subdivisions,2YQ57@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar assembly protein FliH	fliH	-	-	ko:K02411	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliH
k59_1116650_1	1120999.JONM01000013_gene2127	2.72e-57	200.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VJMN@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,EAL,GGDEF,HAMP,MASE1,PAS_3,PAS_4,PAS_8,PAS_9
k59_999612_1	159087.Daro_4151	1.4e-09	56.6	COG2137@1|root,COG2137@2|Bacteria,1N6P6@1224|Proteobacteria,2VTYZ@28216|Betaproteobacteria,2KXFY@206389|Rhodocyclales	206389|Rhodocyclales	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
k59_999612_2	1304883.KI912532_gene882	1.45e-95	283.0	COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,2VH29@28216|Betaproteobacteria,2KUNS@206389|Rhodocyclales	206389|Rhodocyclales	S	ABC-type (Unclassified) transport system, ATPase component	-	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
k59_882058_1	159087.Daro_2771	8.46e-64	202.0	COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,2VK6C@28216|Betaproteobacteria,2KXZ1@206389|Rhodocyclales	206389|Rhodocyclales	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_1586734_1	1249480.B649_01170	1.57e-222	635.0	COG1034@1|root,COG1034@2|Bacteria,1RCFT@1224|Proteobacteria,42NK4@68525|delta/epsilon subdivisions,2YNI6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G)	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4_10,Molybdopterin,NADH-G_4Fe-4S_3
k59_294930_1	159087.Daro_3137	4.75e-157	450.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,2VK35@28216|Betaproteobacteria,2KVMP@206389|Rhodocyclales	206389|Rhodocyclales	S	sulfide dehydrogenase	soxF	-	1.8.2.1	ko:K05301	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00528	RC00168	ko00000,ko00001,ko01000	-	-	-	FCSD-flav_bind,Pyr_redox_2,TAT_signal
k59_1821786_1	1538295.JY96_13735	7.19e-46	168.0	COG1629@1|root,COG4771@2|Bacteria,1MW7D@1224|Proteobacteria,2VIV2@28216|Betaproteobacteria,1KMQW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_764461_1	159087.Daro_1283	1.79e-109	324.0	COG2956@1|root,COG2956@2|Bacteria,1MVDP@1224|Proteobacteria,2VH49@28216|Betaproteobacteria,2KU7Z@206389|Rhodocyclales	206389|Rhodocyclales	G	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane	lapB	-	-	ko:K19804	-	-	-	-	ko00000	-	-	-	TPR_16
k59_1468877_1	563040.Saut_0295	3.47e-36	124.0	COG0694@1|root,COG0694@2|Bacteria,1MVQ1@1224|Proteobacteria,42V85@68525|delta/epsilon subdivisions,2YPSA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Nitrogen fixation protein NifU	-	-	-	-	-	-	-	-	-	-	-	-	NifU
k59_1468877_2	1165841.SULAR_07880	9.96e-74	225.0	2AJZN@1|root,31ANZ@2|Bacteria,1Q5WH@1224|Proteobacteria,42UJ4@68525|delta/epsilon subdivisions,2YPXB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1762734_1	709032.Sulku_1745	1.36e-56	182.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,42MAG@68525|delta/epsilon subdivisions,2YM8T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the TrpC family	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
k59_1762734_2	709032.Sulku_1754	1.18e-41	147.0	COG2308@1|root,COG2308@2|Bacteria,1MUAD@1224|Proteobacteria,42MA8@68525|delta/epsilon subdivisions,2YNA8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
k59_1293160_1	1168067.JAGP01000001_gene231	1.31e-50	164.0	COG1586@1|root,COG1586@2|Bacteria,1RH88@1224|Proteobacteria,1S7BA@1236|Gammaproteobacteria,4619B@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine	speH	-	4.1.1.50	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	M00034,M00133	R00178	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_dc
k59_1293160_2	214092.YPO3411	1.62e-37	135.0	COG0421@1|root,COG0421@2|Bacteria,1MVV5@1224|Proteobacteria,1RMUT@1236|Gammaproteobacteria,41D9P@629|Yersinia	1236|Gammaproteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	GO:0003674,GO:0003824,GO:0004766,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0010487,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0043918,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	iECED1_1282.ECED1_0125,iPC815.YPO3411,iSDY_1059.SDY_0028	Spermine_synt_N,Spermine_synth
k59_2186_1	1304883.KI912532_gene1155	2.09e-40	144.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,2VHBB@28216|Betaproteobacteria,2KUR1@206389|Rhodocyclales	206389|Rhodocyclales	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
k59_2186_2	159087.Daro_3852	3.41e-50	164.0	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,2VQ1Z@28216|Betaproteobacteria,2KVRN@206389|Rhodocyclales	206389|Rhodocyclales	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
k59_1058034_2	709032.Sulku_2503	3.65e-70	216.0	COG4106@1|root,COG4106@2|Bacteria,1QZ2S@1224|Proteobacteria,43CEU@68525|delta/epsilon subdivisions,2YTCB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Methyltransferase domain	-	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
k59_823527_1	709032.Sulku_0182	2.41e-126	365.0	COG0492@1|root,COG0492@2|Bacteria,1NDW6@1224|Proteobacteria,42MUD@68525|delta/epsilon subdivisions,2YMV2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	pyridine nucleotide-disulfide oxidoreductase	trxB_2	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	FixS,Pyr_redox_3
k59_236459_1	1537917.JU82_06280	3.63e-130	374.0	COG0426@1|root,COG0426@2|Bacteria,1N2Y0@1224|Proteobacteria,42WJ3@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_764494_1	1165841.SULAR_03722	2.74e-70	229.0	COG0129@1|root,COG0129@2|Bacteria,1MU3T@1224|Proteobacteria,42P5S@68525|delta/epsilon subdivisions,2YNR9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EG	Belongs to the IlvD Edd family	edd	-	4.2.1.12	ko:K01690	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00008	R02036	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
k59_1116722_1	1121448.DGI_0817	1.04e-56	200.0	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WJCX@28221|Deltaproteobacteria,2MH92@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,CHASE,DUF3365,GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_530365_1	1304883.KI912532_gene1330	1.78e-11	63.2	COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,2VIN4@28216|Betaproteobacteria,2KV9H@206389|Rhodocyclales	206389|Rhodocyclales	H	Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX	hemF	GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	-	Coprogen_oxidas
k59_530365_2	216142.LT40_17650	1.58e-27	115.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
k59_471431_1	1249480.B649_09050	3.37e-23	102.0	COG0457@1|root,COG0457@2|Bacteria,1QV15@1224|Proteobacteria,42NKI@68525|delta/epsilon subdivisions,2YMKG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	COG0457 FOG TPR repeat	pflB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_6,TPR_8
k59_1762790_1	1249480.B649_00195	5.72e-95	285.0	COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,42PGR@68525|delta/epsilon subdivisions,2YRIC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PFAM metal-dependent phosphohydrolase HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
k59_294992_1	1249480.B649_05345	5.72e-77	249.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,42WJ0@68525|delta/epsilon subdivisions,2YQJR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	PFAM TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_471457_1	1454004.AW11_01445	7.59e-87	259.0	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,2VQ1Z@28216|Betaproteobacteria,1KQ0W@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
k59_999711_1	1304883.KI912532_gene402	1.03e-125	382.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,2VIAH@28216|Betaproteobacteria,2KU6Z@206389|Rhodocyclales	206389|Rhodocyclales	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
k59_1116763_1	1485544.JQKP01000003_gene130	5.1e-74	232.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,2VHF7@28216|Betaproteobacteria,44V8E@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,S4_2,tRNA-synt_1b
k59_1116763_2	395494.Galf_0360	1.12e-18	84.3	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2VHBS@28216|Betaproteobacteria,44V44@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_823591_1	563040.Saut_0660	3.66e-28	117.0	COG1283@1|root,COG1283@2|Bacteria,1MUDE@1224|Proteobacteria,42PW9@68525|delta/epsilon subdivisions,2YN4S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Na Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans
k59_1116782_1	159087.Daro_3005	1.87e-166	471.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,2VH1F@28216|Betaproteobacteria,2KUMQ@206389|Rhodocyclales	206389|Rhodocyclales	T	response regulator	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
k59_1175945_1	159087.Daro_1214	3.91e-47	169.0	COG3170@1|root,COG3170@2|Bacteria,1RE27@1224|Proteobacteria,2VRNH@28216|Betaproteobacteria,2KW0V@206389|Rhodocyclales	206389|Rhodocyclales	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_941040_1	1249480.B649_07225	1.74e-95	278.0	COG0698@1|root,COG0698@2|Bacteria,1RHBF@1224|Proteobacteria,42SAN@68525|delta/epsilon subdivisions,2YPGI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
k59_941040_2	1249480.B649_07220	2.46e-67	209.0	COG1994@1|root,COG1994@2|Bacteria,1N531@1224|Proteobacteria,43AZN@68525|delta/epsilon subdivisions,2YP0U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
k59_1586860_1	90814.KL370891_gene687	8.04e-39	141.0	COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,1RN0Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	fliC	GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_IN,Flagellin_N
k59_1410337_1	709032.Sulku_1387	1.42e-134	397.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,42PUI@68525|delta/epsilon subdivisions,2YN3E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	PFAM TrkA-N domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2,TrkA_N
k59_705981_1	1123393.KB891316_gene1281	6.72e-187	529.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,1KSTW@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_1468974_1	709032.Sulku_0739	6.39e-88	278.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2YN6Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DNA mismatch repair MutS family	-	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_III,MutS_V
k59_1468974_2	1537917.JU82_04560	3.31e-48	163.0	COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,42MJ1@68525|delta/epsilon subdivisions,2YMZ8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0212	M20_dimer,Peptidase_M20
k59_1175959_1	879212.DespoDRAFT_01505	2.64e-32	117.0	COG2246@1|root,COG2246@2|Bacteria,1NBR4@1224|Proteobacteria,42V1A@68525|delta/epsilon subdivisions,2WS9I@28221|Deltaproteobacteria,2MKWQ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
k59_1645339_1	159087.Daro_0733	6.06e-53	167.0	COG1366@1|root,COG1366@2|Bacteria,1MZ5N@1224|Proteobacteria,2VWS3@28216|Betaproteobacteria,2KX88@206389|Rhodocyclales	206389|Rhodocyclales	T	STAS domain	-	-	-	ko:K20978	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001	-	-	-	STAS_2
k59_1645339_2	159087.Daro_0734	1.07e-91	275.0	COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1N81M@1224|Proteobacteria,2VI4E@28216|Betaproteobacteria,2KVCH@206389|Rhodocyclales	206389|Rhodocyclales	T	Chemotaxis signal transduction protein	-	-	-	ko:K03415	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CheW,Response_reg
k59_999770_1	709032.Sulku_1820	6.1e-67	207.0	COG0741@1|root,COG0741@2|Bacteria,1Q433@1224|Proteobacteria,432ZU@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	Transglycosylase SLT domain	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	SLT
k59_414969_1	202954.BBNK01000023_gene3247	7.02e-43	149.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,1RMR8@1236|Gammaproteobacteria,3NKRW@468|Moraxellaceae	1236|Gammaproteobacteria	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
k59_414969_2	709032.Sulku_1874	1.75e-47	169.0	COG3746@1|root,COG3746@2|Bacteria,1MY3M@1224|Proteobacteria,42NVN@68525|delta/epsilon subdivisions,2YMH8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1706492_2	709032.Sulku_1434	1.66e-153	434.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,42MMS@68525|delta/epsilon subdivisions,2YMA2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	hydrolase, TatD	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
k59_5611_1	190486.XAC3028	1.1e-06	53.5	COG0642@1|root,COG0784@1|root,COG3292@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1X4Y5@135614|Xanthomonadales	135614|Xanthomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Reg_prop,Response_reg,Y_Y_Y
k59_5611_2	159087.Daro_3348	1.19e-19	84.0	2D2K4@1|root,32TD0@2|Bacteria,1MZKF@1224|Proteobacteria,2VUUX@28216|Betaproteobacteria,2KZ3H@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF3124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3124
k59_1295449_2	1537917.JU82_03275	4.68e-90	284.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42MCY@68525|delta/epsilon subdivisions,2YMB3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB1	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
k59_1824993_1	1123355.JHYO01000001_gene3269	1.24e-16	84.3	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
k59_1119790_1	1165841.SULAR_07138	7.27e-73	226.0	COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,42MES@68525|delta/epsilon subdivisions,2YMU9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
k59_591106_1	317025.Tcr_0327	2.18e-63	200.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria,460QZ@72273|Thiotrichales	72273|Thiotrichales	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
k59_1119803_1	1132855.KB913035_gene1920	5.52e-163	474.0	COG0296@1|root,COG0296@2|Bacteria,1MVM7@1224|Proteobacteria,2W14D@28216|Betaproteobacteria,2KM8E@206350|Nitrosomonadales	206350|Nitrosomonadales	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
k59_1295464_1	159087.Daro_2726	4.73e-51	162.0	2B58A@1|root,31Y28@2|Bacteria,1RHG1@1224|Proteobacteria,2WDKE@28216|Betaproteobacteria,2KZ0S@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF2502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2502
k59_1295464_2	159087.Daro_2727	5.87e-21	91.3	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,2VHYF@28216|Betaproteobacteria,2KVIZ@206389|Rhodocyclales	206389|Rhodocyclales	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_826381_1	653733.Selin_0477	1.01e-98	295.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23,HTH_32
k59_884700_1	929558.SMGD1_0680	1.49e-47	174.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,43AX5@68525|delta/epsilon subdivisions,2YT40@29547|Epsilonproteobacteria	1224|Proteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_9,Response_reg
k59_533485_1	709032.Sulku_0706	3.2e-101	304.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,42UPM@68525|delta/epsilon subdivisions,2YRIE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL
k59_121606_1	1095769.CAHF01000006_gene1988	2.6e-116	355.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,2VHUG@28216|Betaproteobacteria	28216|Betaproteobacteria	S	TRAP transporter 4TM 12TM fusion	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k59_62592_2	187272.Mlg_1665	2.72e-64	212.0	COG0547@1|root,COG0547@2|Bacteria,1QJ8Q@1224|Proteobacteria,1RY26@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Glycosyl transferase	ybiB	GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363	-	-	-	-	-	-	-	-	-	-	Glycos_trans_3N,Glycos_transf_3
k59_1354039_1	1485544.JQKP01000002_gene1361	5.04e-72	241.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,44W6J@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Phosphonate-bd
k59_1002434_1	1121035.AUCH01000009_gene805	6.28e-86	259.0	COG2207@1|root,COG3449@1|root,COG2207@2|Bacteria,COG3449@2|Bacteria,1MWTF@1224|Proteobacteria,2VNPZ@28216|Betaproteobacteria,2KXFW@206389|Rhodocyclales	206389|Rhodocyclales	KL	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K13652	-	-	-	-	ko00000,ko03000	-	-	-	GyrI-like,HTH_18
k59_1002435_1	387093.SUN_2425	1.26e-36	136.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,42M20@68525|delta/epsilon subdivisions,2YMDG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
k59_1002435_2	1165841.SULAR_08192	1.34e-59	187.0	COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,42RHA@68525|delta/epsilon subdivisions,2YNX4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
k59_1178439_1	709032.Sulku_1371	9.59e-87	262.0	COG0664@1|root,COG0664@2|Bacteria,1MZZD@1224|Proteobacteria,42QUX@68525|delta/epsilon subdivisions,2YP2C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator	nssR	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
k59_415034_1	398527.Bphyt_1245	2.39e-41	147.0	COG0027@1|root,COG0027@2|Bacteria,1N3KA@1224|Proteobacteria,2VH4M@28216|Betaproteobacteria,1K1VT@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate	purT	-	2.1.2.2	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp,Epimerase
k59_415034_2	981336.F944_02139	0.000115	43.5	COG2703@1|root,COG2703@2|Bacteria,1RI40@1224|Proteobacteria,1S705@1236|Gammaproteobacteria,3NKT1@468|Moraxellaceae	1236|Gammaproteobacteria	P	Hemerythrin HHE cation binding domain	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
k59_474170_1	159087.Daro_1168	4.93e-134	390.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2W3RM@28216|Betaproteobacteria,2KZWY@206389|Rhodocyclales	206389|Rhodocyclales	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_1471545_1	709032.Sulku_2491	4.89e-130	395.0	COG0243@1|root,COG0243@2|Bacteria,1NSXR@1224|Proteobacteria,43BQI@68525|delta/epsilon subdivisions,2YRHF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	ko:K17050	-	-	-	-	ko00000,ko02000	5.A.3.8	-	-	Molybdopterin,Molydop_binding
k59_62614_1	1249480.B649_03030	5.41e-72	228.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,42MMY@68525|delta/epsilon subdivisions,2YMDM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	dihydropteroate synthase	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
k59_1002464_1	159087.Daro_3962	2.63e-69	223.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,2KUEY@206389|Rhodocyclales	206389|Rhodocyclales	T	Bacterial regulatory protein, Fis family	hoxA	-	-	ko:K19641	ko02020,map02020	M00772	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_1002464_2	159087.Daro_3963	1.45e-54	185.0	COG0223@1|root,COG1024@1|root,COG0223@2|Bacteria,COG1024@2|Bacteria,1MWYJ@1224|Proteobacteria,2VK38@28216|Betaproteobacteria,2KVS4@206389|Rhodocyclales	206389|Rhodocyclales	IJ	Formyl transferase, C-terminal domain	-	-	-	ko:K19640	-	-	-	-	ko00000,ko02022	-	-	-	ECH_1,Formyl_trans_C,Formyl_trans_N
k59_1471570_2	1353531.AZNX01000001_gene1619	3.7e-50	167.0	COG1442@1|root,COG1442@2|Bacteria,1QH4S@1224|Proteobacteria,2U9KQ@28211|Alphaproteobacteria,4B9U9@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	glycosyl transferase family 8	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_495820_3	1249480.B649_00595	3.32e-41	151.0	COG0715@1|root,COG0834@1|root,COG4191@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PNA@68525|delta/epsilon subdivisions,2YTBI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EPT	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,NMT1,SBP_bac_3
k59_964763_1	870187.Thini_2468	2.3e-76	250.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,1RNB2@1236|Gammaproteobacteria,45ZT1@72273|Thiotrichales	72273|Thiotrichales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_1261426_1	709032.Sulku_2056	4.36e-101	308.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,42M4S@68525|delta/epsilon subdivisions,2YM8Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	-	-	1.12.5.1	ko:K05922	-	-	-	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
k59_1848086_2	1249480.B649_01215	0.0	948.0	COG0457@1|root,COG0457@2|Bacteria,1QV1A@1224|Proteobacteria,42MIW@68525|delta/epsilon subdivisions,2YMDB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Paralysed flagella protein	pflA	-	-	-	-	-	-	-	-	-	-	-	TPR_21,TPR_6,TPR_8,YfiO
k59_846831_2	1537917.JU82_02925	6.63e-114	337.0	2AIMJ@1|root,3193W@2|Bacteria,1Q1QU@1224|Proteobacteria,42U73@68525|delta/epsilon subdivisions,2YSXF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_612587_1	153948.NAL212_0412	1.49e-55	186.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2VI5U@28216|Betaproteobacteria,3722F@32003|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
k59_612587_2	640081.Dsui_0042	3.53e-28	102.0	2EGD6@1|root,33A4Z@2|Bacteria,1N733@1224|Proteobacteria,2VVS2@28216|Betaproteobacteria,2KX8R@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
k59_612587_3	1097668.BYI23_A015830	7.61e-06	46.2	COG0314@1|root,COG0314@2|Bacteria,1RGUX@1224|Proteobacteria,2VRMG@28216|Betaproteobacteria,1K74K@119060|Burkholderiaceae	28216|Betaproteobacteria	H	PFAM molybdopterin biosynthesis MoaE	moaE	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
k59_78563_1	709032.Sulku_0560	6.01e-116	350.0	COG2199@1|root,COG2200@1|root,COG3620@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,COG3620@2|Bacteria,1MVJY@1224|Proteobacteria,42N7E@68525|delta/epsilon subdivisions,2YNE7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PFAM EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF
k59_1373765_1	1292034.OR37_03649	9.65e-11	68.2	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,2KIWU@204458|Caulobacterales	204458|Caulobacterales	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
k59_1725554_2	640081.Dsui_1316	1.26e-41	142.0	COG2928@1|root,COG2928@2|Bacteria,1MWT5@1224|Proteobacteria,2VH65@28216|Betaproteobacteria,2KV5C@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
k59_144376_1	1123517.JOMR01000001_gene658	2.26e-239	662.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,1RM98@1236|Gammaproteobacteria,4602C@72273|Thiotrichales	72273|Thiotrichales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
k59_144376_2	2340.JV46_20290	1.45e-28	108.0	COG0852@1|root,COG0852@2|Bacteria,1MX4B@1224|Proteobacteria,1S2ET@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
k59_1081447_2	1537917.JU82_11820	6.61e-20	89.0	COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,42N49@68525|delta/epsilon subdivisions,2YND2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA
k59_144392_1	1304883.KI912532_gene1194	2.8e-59	195.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,2VHYE@28216|Betaproteobacteria,2KV8R@206389|Rhodocyclales	206389|Rhodocyclales	E	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k59_144392_2	159087.Daro_3762	2.69e-12	64.3	2BWQ4@1|root,32QZV@2|Bacteria,1MZQ9@1224|Proteobacteria,2VSNR@28216|Betaproteobacteria,2KWKW@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of unknown function (DUF4124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124
k59_1027908_1	990073.ATHU01000001_gene1211	9.6e-27	102.0	COG1051@1|root,COG1051@2|Bacteria,1QUM0@1224|Proteobacteria,42SY6@68525|delta/epsilon subdivisions,2YPEG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	ADP-ribose pyrophosphatase	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
k59_1027908_2	709032.Sulku_1651	3.48e-62	193.0	2EE7S@1|root,3382A@2|Bacteria,1NFK6@1224|Proteobacteria,42XB1@68525|delta/epsilon subdivisions,2YQX5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1027908_4	1537917.JU82_04270	2.24e-15	71.6	COG2983@1|root,COG2983@2|Bacteria,1RHMX@1224|Proteobacteria,42UC9@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Belongs to the UPF0260 family	MA20_15575	-	-	ko:K09160	-	-	-	-	ko00000	-	-	-	CxxCxxCC
k59_198914_2	1419583.V466_04000	4.3e-48	170.0	COG4618@1|root,COG4618@2|Bacteria,1NTI5@1224|Proteobacteria,1T1HR@1236|Gammaproteobacteria,1YRK3@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06148,ko:K12536	ko02010,map02010	M00328	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1,3.A.1.110	-	-	ABC_membrane,ABC_tran
k59_1491338_1	709032.Sulku_2486	2.64e-210	586.0	COG1149@1|root,COG1149@2|Bacteria,1R1KA@1224|Proteobacteria,43DAS@68525|delta/epsilon subdivisions,2YTHU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
k59_674430_1	207559.Dde_0399	5.52e-30	110.0	COG0440@1|root,COG0440@2|Bacteria,1N065@1224|Proteobacteria,42V6V@68525|delta/epsilon subdivisions,2WS7E@28221|Deltaproteobacteria,2MCJI@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM Amino acid-binding ACT	ilvN	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5
k59_674430_2	159087.Daro_2497	1.3e-28	112.0	COG0840@1|root,COG0840@2|Bacteria,1R5W9@1224|Proteobacteria,2VKQP@28216|Betaproteobacteria,2KVCX@206389|Rhodocyclales	206389|Rhodocyclales	NT	Chemoreceptor zinc-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CZB,MCPsignal
k59_1196920_1	159087.Daro_1052	7.51e-159	461.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KYB0@206389|Rhodocyclales	206389|Rhodocyclales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_198931_1	1249480.B649_02960	9.73e-24	92.8	COG1826@1|root,COG1826@2|Bacteria,1NI3F@1224|Proteobacteria,42VD0@68525|delta/epsilon subdivisions,2YQ93@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation	tatB	-	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
k59_198931_2	1249480.B649_02965	5.69e-104	311.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,42NGU@68525|delta/epsilon subdivisions,2YMCD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN2	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k59_1725616_2	1433126.BN938_2438	1.46e-39	144.0	COG3039@1|root,COG3039@2|Bacteria,4NPH8@976|Bacteroidetes,2G2I4@200643|Bacteroidia	976|Bacteroidetes	L	Transposase domain (DUF772)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
k59_557481_1	338969.Rfer_3722	4.5e-78	243.0	COG1705@1|root,COG3951@1|root,COG1705@2|Bacteria,COG3951@2|Bacteria,1MX2W@1224|Proteobacteria,2VH35@28216|Betaproteobacteria,4AA5N@80864|Comamonadaceae	28216|Betaproteobacteria	N	Flagellar rod assembly protein muramidase FlgJ	flgJ	-	-	ko:K02395	-	-	-	-	ko00000,ko02035	-	-	-	Glucosaminidase,Rod-binding
k59_1608106_1	1132855.KB913035_gene258	2.03e-137	427.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,2VHUY@28216|Betaproteobacteria,2KM55@206350|Nitrosomonadales	206350|Nitrosomonadales	E	glutamate synthase, alpha subunit domain protein	-	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_1491382_1	387093.SUN_1079	7.7e-46	155.0	COG0688@1|root,COG0688@2|Bacteria,1MVT4@1224|Proteobacteria,42PAW@68525|delta/epsilon subdivisions,2YNM3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
k59_1491382_2	387093.SUN_1080	3.31e-27	107.0	COG0119@1|root,COG0119@2|Bacteria,1QYY7@1224|Proteobacteria,43CMC@68525|delta/epsilon subdivisions,2YTE6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1608114_1	159087.Daro_2940	5.46e-20	88.2	COG1858@1|root,COG1858@2|Bacteria,1QVCJ@1224|Proteobacteria,2VIIC@28216|Betaproteobacteria,2KY5V@206389|Rhodocyclales	206389|Rhodocyclales	C	cytochrome C peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1608114_2	159087.Daro_2939	2.6e-78	246.0	COG1858@1|root,COG1858@2|Bacteria,1QVCJ@1224|Proteobacteria,2VIF0@28216|Betaproteobacteria,2KXPU@206389|Rhodocyclales	206389|Rhodocyclales	C	cytochrome C peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
k59_22153_1	873513.HMPREF6485_1684	1.31e-29	122.0	COG0304@1|root,COG0304@2|Bacteria,4NFC8@976|Bacteroidetes,2FPUI@200643|Bacteroidia	976|Bacteroidetes	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_846927_1	706587.Desti_3259	6.74e-41	159.0	COG0784@1|root,COG2197@1|root,COG2202@1|root,COG3829@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2197@2|Bacteria,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIU5@28221|Deltaproteobacteria,2MQZQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_199004_1	1123020.AUIE01000005_gene4468	5.76e-18	84.3	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,1YE1C@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	yngI	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
k59_199004_2	398578.Daci_3350	3.12e-64	210.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VHNV@28216|Betaproteobacteria,4AB55@80864|Comamonadaceae	28216|Betaproteobacteria	C	belongs to the aldehyde dehydrogenase family	-	-	1.2.1.39	ko:K00146	ko00360,ko00643,ko01100,ko01120,map00360,map00643,map01100,map01120	-	R02536	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
k59_433523_1	159087.Daro_2396	8.92e-91	273.0	COG0476@1|root,COG0476@2|Bacteria,1QUMS@1224|Proteobacteria,2VN2Y@28216|Betaproteobacteria,2KUIK@206389|Rhodocyclales	206389|Rhodocyclales	H	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2	-	-	-	-	-	-	-	-	-	-	-	-	ThiF
k59_1784292_1	204536.SULAZ_0227	4.97e-57	199.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria	2|Bacteria	T	EAL domain	yliE	GO:0003674,GO:0003824,GO:0008081,GO:0016787,GO:0016788,GO:0042578,GO:0071111	-	-	-	-	-	-	-	-	-	-	CHASE9,EAL,GGDEF,PAS_9,Peripla_BP_3
k59_1261627_1	709032.Sulku_1997	7.22e-103	319.0	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42Z31@68525|delta/epsilon subdivisions,2YRAR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Hpt sensor hybrid histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
k59_78681_1	358220.C380_07340	4.1e-38	143.0	COG0438@1|root,COG0438@2|Bacteria,1R564@1224|Proteobacteria,2VTN6@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Glycosyltransferase, group 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_1667675_1	1537917.JU82_01070	1.08e-18	83.2	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,42MEE@68525|delta/epsilon subdivisions,2YN8Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
k59_1609916_2	235279.HH_1795	1.86e-45	167.0	COG2604@1|root,COG2604@2|Bacteria,1R4P0@1224|Proteobacteria,42NB8@68525|delta/epsilon subdivisions,2YMMI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	hmm pf01973	pseE	-	-	-	-	-	-	-	-	-	-	-	MAF_flag10
k59_1198775_2	1165841.SULAR_08437	4.9e-12	61.2	COG0011@1|root,COG0011@2|Bacteria,1N0UT@1224|Proteobacteria,43B8R@68525|delta/epsilon subdivisions,2YT6Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Thiamine-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
k59_1493004_1	1429851.X548_08195	2.22e-07	52.8	COG1419@1|root,COG1419@2|Bacteria,1MUQW@1224|Proteobacteria,1RMUU@1236|Gammaproteobacteria,1X3K0@135614|Xanthomonadales	135614|Xanthomonadales	N	flagellar	flhF	-	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	SRP54
k59_1493004_2	1123518.ARWI01000001_gene597	7.38e-39	145.0	COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,1RMSM@1236|Gammaproteobacteria,4604H@72273|Thiotrichales	72273|Thiotrichales	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
k59_146381_1	90814.KL370891_gene308	5.51e-126	384.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,1RNR3@1236|Gammaproteobacteria,45ZWF@72273|Thiotrichales	72273|Thiotrichales	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
k59_789156_1	709032.Sulku_1505	1.38e-74	243.0	COG2199@1|root,COG3706@2|Bacteria,1R1K2@1224|Proteobacteria,42YWW@68525|delta/epsilon subdivisions,2YR1I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Double sensory domain of two-component sensor kinase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_3
k59_375320_1	870187.Thini_3910	6.47e-44	145.0	COG3123@1|root,COG3123@2|Bacteria,1MZ8N@1224|Proteobacteria,1T07B@1236|Gammaproteobacteria,463RI@72273|Thiotrichales	72273|Thiotrichales	S	Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions	ppnP	-	-	-	-	-	-	-	-	-	-	-	DUF1255
k59_498198_1	748247.AZKH_2708	4.6e-71	238.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,2KYCC@206389|Rhodocyclales	206389|Rhodocyclales	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.9	ko:K01539	ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978	-	-	-	ko00000,ko00001,ko01000,ko04147	3.A.3.1	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
k59_848398_1	765913.ThidrDRAFT_4228	1.07e-79	252.0	COG0189@1|root,COG0189@2|Bacteria,1NNP5@1224|Proteobacteria,1RRUB@1236|Gammaproteobacteria,1WW74@135613|Chromatiales	135613|Chromatiales	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1850660_1	929558.SMGD1_2241	3.02e-72	225.0	COG1969@1|root,COG1969@2|Bacteria,1MU87@1224|Proteobacteria,42NQ3@68525|delta/epsilon subdivisions,2YMRF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Ni Fe-hydrogenase, b-type cytochrome subunit	hydC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
k59_1264015_1	1095769.CAHF01000006_gene1733	1.9e-97	289.0	COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,2VIZW@28216|Betaproteobacteria,4731K@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	modB	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
k59_676911_1	870187.Thini_2516	2.7e-76	239.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,1RP1T@1236|Gammaproteobacteria,45ZQR@72273|Thiotrichales	72273|Thiotrichales	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
k59_559985_1	1537917.JU82_04980	3.22e-121	356.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,42N4K@68525|delta/epsilon subdivisions,2YMXB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
k59_559991_2	1249480.B649_05785	5.01e-73	228.0	COG0791@1|root,COG0791@2|Bacteria,1N0EE@1224|Proteobacteria,42V3C@68525|delta/epsilon subdivisions,2YQCX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	NlpC/P60 family	-	-	3.4.17.13	ko:K13694,ko:K13695	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60,SPOR
k59_1375874_2	717773.Thicy_0843	2.05e-61	192.0	COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,1RPW7@1236|Gammaproteobacteria,460D8@72273|Thiotrichales	72273|Thiotrichales	J	Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
k59_1609964_1	709032.Sulku_0101	1.13e-101	298.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,42RI5@68525|delta/epsilon subdivisions,2YP6Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0831	CoaE
k59_201405_1	159087.Daro_1946	5.14e-131	389.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,2VMB2@28216|Betaproteobacteria,2KVR7@206389|Rhodocyclales	206389|Rhodocyclales	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_201405_2	159087.Daro_1945	4.94e-36	124.0	COG0236@1|root,COG0236@2|Bacteria	2|Bacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
k59_201405_3	1380390.JIAT01000009_gene509	7.79e-07	50.4	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4CRI8@84995|Rubrobacteria	84995|Rubrobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_3,GGDEF
k59_314822_1	1249480.B649_03860	8.53e-192	542.0	COG4942@1|root,COG4942@2|Bacteria,1QV6K@1224|Proteobacteria,42M9V@68525|delta/epsilon subdivisions,2YMS7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_1786133_2	159087.Daro_0335	6.62e-69	209.0	COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,2VSH0@28216|Betaproteobacteria,2KWNI@206389|Rhodocyclales	206389|Rhodocyclales	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
k59_1439602_1	1537917.JU82_08060	4.03e-214	598.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,42MDB@68525|delta/epsilon subdivisions,2YMF9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7,Pribosyltran
k59_615468_1	1249480.B649_01790	2.46e-46	154.0	COG0047@1|root,COG0047@2|Bacteria,1MU4Y@1224|Proteobacteria,42MNY@68525|delta/epsilon subdivisions,2YMTM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
k59_1083649_1	582744.Msip34_1604	6.72e-91	271.0	COG2135@1|root,COG2135@2|Bacteria,1RFZU@1224|Proteobacteria,2VQDU@28216|Betaproteobacteria,2KN0G@206350|Nitrosomonadales	206350|Nitrosomonadales	S	SOS response associated peptidase (SRAP)	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
k59_1313294_1	765911.Thivi_2664	5.91e-129	379.0	COG3464@1|root,COG3464@2|Bacteria,1R8B7@1224|Proteobacteria,1SHHY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	UPF0236
k59_80462_1	1537917.JU82_01060	8.15e-86	259.0	COG1058@1|root,COG1058@2|Bacteria,1MVG6@1224|Proteobacteria,42R50@68525|delta/epsilon subdivisions,2YNX5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
k59_23690_1	743299.Acife_0566	2.35e-56	185.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,1RMGV@1236|Gammaproteobacteria,2NBQ0@225057|Acidithiobacillales	225057|Acidithiobacillales	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
k59_1786188_1	1249480.B649_07470	3.04e-14	71.6	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42M01@68525|delta/epsilon subdivisions,2YMF7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	ABC transporter	msbA	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
k59_260275_2	1384049.CD29_18710	1.85e-07	52.0	COG0563@1|root,COG0563@2|Bacteria,1V1QU@1239|Firmicutes,4HGI2@91061|Bacilli,3IZPS@400634|Lysinibacillus	91061|Bacilli	F	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_18,SKI
k59_1198907_1	1249480.B649_04975	3.99e-65	203.0	COG1286@1|root,COG1286@2|Bacteria,1NIBK@1224|Proteobacteria,42U0P@68525|delta/epsilon subdivisions,2YPS8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Colicin V production protein	cvpA	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
k59_80466_1	717773.Thicy_0617	1.14e-118	343.0	COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,1RNMK@1236|Gammaproteobacteria,45ZQ2@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
k59_80466_2	1027292.HMPREF9372_1045	9.62e-21	90.5	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,4HAWA@91061|Bacilli,26DRQ@186818|Planococcaceae	91061|Bacilli	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS10700	Aconitase
k59_1786197_1	1123401.JHYQ01000025_gene3312	4.1e-31	125.0	COG1944@1|root,COG1944@2|Bacteria,1MV7K@1224|Proteobacteria,1RN47@1236|Gammaproteobacteria,45ZWA@72273|Thiotrichales	72273|Thiotrichales	O	YcaO cyclodehydratase, ATP-ad Mg2+-binding	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	YcaO
k59_1786197_2	1123400.KB904813_gene3070	7.14e-13	65.9	COG2010@1|root,COG2010@2|Bacteria,1N71Z@1224|Proteobacteria,1SH2C@1236|Gammaproteobacteria,461FB@72273|Thiotrichales	72273|Thiotrichales	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1727829_2	1502770.JQMG01000001_gene373	1.15e-05	47.4	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,2VMSZ@28216|Betaproteobacteria,2KMS6@206350|Nitrosomonadales	206350|Nitrosomonadales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,GGDEF,PAS_9
k59_1375960_1	1249480.B649_02180	2.2e-140	398.0	COG0745@1|root,COG0745@2|Bacteria,1Q456@1224|Proteobacteria,42RZX@68525|delta/epsilon subdivisions,2YP60@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_1375960_2	709032.Sulku_0442	1.61e-160	457.0	COG0840@1|root,COG0840@2|Bacteria,1QZ1R@1224|Proteobacteria,42SSJ@68525|delta/epsilon subdivisions,2YPF5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	transmembrane signaling receptor activity	-	-	-	-	-	-	-	-	-	-	-	-	dCache_3
k59_1439696_1	1249480.B649_03825	4.35e-48	159.0	COG2307@1|root,COG2307@2|Bacteria,1NMSC@1224|Proteobacteria,42V9T@68525|delta/epsilon subdivisions,2YQAK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
k59_1517577_1	1249480.B649_05030	2.27e-44	147.0	COG1917@1|root,COG1917@2|Bacteria,1QTHP@1224|Proteobacteria,42VCM@68525|delta/epsilon subdivisions,2YQD1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	conserved protein, contains double-stranded beta-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2
k59_1517577_2	1537917.JU82_02775	9.82e-48	158.0	COG1521@1|root,COG1521@2|Bacteria,1PZXA@1224|Proteobacteria,42RA8@68525|delta/epsilon subdivisions,2YP14@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
k59_1290003_1	159087.Daro_3987	2.27e-93	276.0	COG1969@1|root,COG1969@2|Bacteria,1MU87@1224|Proteobacteria,2VI8M@28216|Betaproteobacteria,2KV5F@206389|Rhodocyclales	206389|Rhodocyclales	C	Prokaryotic cytochrome b561	-	-	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
k59_1290003_2	1121035.AUCH01000003_gene1255	1.99e-12	65.9	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,2VJ52@28216|Betaproteobacteria,2KV5T@206389|Rhodocyclales	206389|Rhodocyclales	C	Nickel-dependent hydrogenase	-	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
k59_745132_1	159087.Daro_1471	7.81e-51	171.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1MWHZ@1224|Proteobacteria,2VH9M@28216|Betaproteobacteria,2KV6W@206389|Rhodocyclales	206389|Rhodocyclales	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrome_CBB3
k59_745132_2	159087.Daro_1470	3.68e-23	97.8	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,2VHGU@28216|Betaproteobacteria,2KVEH@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
k59_816766_1	1485544.JQKP01000001_gene942	9.37e-25	109.0	COG2132@1|root,COG4733@1|root,COG2132@2|Bacteria,COG4733@2|Bacteria,1R9AF@1224|Proteobacteria,2WF05@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_586468_1	1161935.H9D1G7_9CAUD	3.44e-50	186.0	4QH2I@10239|Viruses,4QWWD@35237|dsDNA viruses  no RNA stage,4QQE9@28883|Caudovirales,4QNFX@10744|Podoviridae	10744|Podoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_522406_1	658086.HMPREF0994_05943	5.66e-12	64.3	COG2020@1|root,COG2020@2|Bacteria,1V3IZ@1239|Firmicutes,24FW3@186801|Clostridia,27NH1@186928|unclassified Lachnospiraceae	186801|Clostridia	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF218,PEMT
k59_522406_2	323848.Nmul_A1561	3.25e-18	82.8	COG3588@1|root,COG3588@2|Bacteria,1MVFK@1224|Proteobacteria,2VMRG@28216|Betaproteobacteria,372J6@32003|Nitrosomonadales	28216|Betaproteobacteria	G	Fructose-bisphosphate aldolase class-I	fbaB	-	4.1.2.13	ko:K01623	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147	-	-	-	Glycolytic
k59_284816_1	1458275.AZ34_06890	3.21e-73	223.0	COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,2VIJC@28216|Betaproteobacteria,4AA66@80864|Comamonadaceae	28216|Betaproteobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
k59_46210_1	717772.THIAE_03680	3.68e-84	263.0	COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,1RNUS@1236|Gammaproteobacteria,45ZUI@72273|Thiotrichales	72273|Thiotrichales	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
k59_1400106_1	1254432.SCE1572_39990	4.9e-05	48.5	29YSD@1|root,30KNG@2|Bacteria,1PRVE@1224|Proteobacteria,4351K@68525|delta/epsilon subdivisions,2X519@28221|Deltaproteobacteria,2YZZ2@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Zn_Tnp_IS91
k59_1636510_1	580332.Slit_2001	2.16e-42	156.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,44V8X@713636|Nitrosomonadales	28216|Betaproteobacteria	V	TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_937568_2	1121097.JCM15093_3133	1.87e-24	96.7	COG1695@1|root,COG1695@2|Bacteria,4NSI4@976|Bacteroidetes,2FTF6@200643|Bacteroidia,4AR21@815|Bacteroidaceae	976|Bacteroidetes	K	transcriptional regulator PadR family	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
k59_820611_1	1165841.SULAR_02743	8.75e-75	238.0	COG0479@1|root,COG0479@2|Bacteria,1QE4T@1224|Proteobacteria,42QE6@68525|delta/epsilon subdivisions,2YM7P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG0479 Succinate dehydrogenase fumarate reductase, Fe-S protein subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_873380_1	1458357.BG58_18255	2.95e-112	327.0	COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,2VP0A@28216|Betaproteobacteria,1K90G@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
k59_463790_1	709032.Sulku_0560	6.69e-64	212.0	COG2199@1|root,COG2200@1|root,COG3620@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,COG3620@2|Bacteria,1MVJY@1224|Proteobacteria,42N7E@68525|delta/epsilon subdivisions,2YNE7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PFAM EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF
k59_748759_1	1537917.JU82_04725	2.85e-49	161.0	COG1739@1|root,COG1739@2|Bacteria,1NFJC@1224|Proteobacteria,42T7W@68525|delta/epsilon subdivisions,2YPM6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	hmm pf01205	-	-	-	-	-	-	-	-	-	-	-	-	DUF1949,UPF0029
k59_748759_2	709032.Sulku_1645	6.42e-13	67.0	COG1651@1|root,COG1651@2|Bacteria,1Q684@1224|Proteobacteria,432K4@68525|delta/epsilon subdivisions,2YSQB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_873402_1	1537917.JU82_03540	2.81e-150	426.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,42M3C@68525|delta/epsilon subdivisions,2YMHJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
k59_1812562_1	1168065.DOK_17680	1.77e-05	46.2	COG2885@1|root,COG2885@2|Bacteria,1R4WG@1224|Proteobacteria,1RZN8@1236|Gammaproteobacteria,1J93K@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Opacity family porin protein	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA,TSP_3
k59_1812562_2	1123517.JOMR01000001_gene342	3.11e-97	301.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1RMWP@1236|Gammaproteobacteria,45ZRU@72273|Thiotrichales	72273|Thiotrichales	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
k59_463818_1	1168067.JAGP01000001_gene1033	2.62e-114	345.0	COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,1RMFY@1236|Gammaproteobacteria,45ZMR@72273|Thiotrichales	72273|Thiotrichales	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
k59_175851_1	1122134.KB893652_gene2429	7.01e-25	94.7	arCOG05874@1|root,2ZJ01@2|Bacteria,1N8VY@1224|Proteobacteria,1SHGZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_748794_1	929558.SMGD1_1442	4.27e-65	206.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,42NEA@68525|delta/epsilon subdivisions,2YN5P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
k59_748794_2	1165841.SULAR_02603	6.69e-22	87.0	2AK6W@1|root,31AX2@2|Bacteria,1Q6DS@1224|Proteobacteria,432YP@68525|delta/epsilon subdivisions,2YSX1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1812589_1	1123517.JOMR01000001_gene904	2.05e-79	252.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPWS@1236|Gammaproteobacteria,45ZW1@72273|Thiotrichales	72273|Thiotrichales	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
k59_526161_1	709032.Sulku_1376	2.54e-144	422.0	COG0515@1|root,COG0631@1|root,COG0515@2|Bacteria,COG0631@2|Bacteria,1MV1P@1224|Proteobacteria,42MVV@68525|delta/epsilon subdivisions,2YNMJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KLT	COG0631 Serine threonine protein phosphatase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PP2C_2,Pkinase
k59_403233_1	159087.Daro_3873	6.27e-177	504.0	COG3287@1|root,COG3287@2|Bacteria,1R825@1224|Proteobacteria,2VPKS@28216|Betaproteobacteria,2KXSM@206389|Rhodocyclales	206389|Rhodocyclales	S	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
k59_1344232_1	1502770.JQMG01000001_gene1353	3.02e-98	290.0	COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,2VQ97@28216|Betaproteobacteria,2KKP8@206350|Nitrosomonadales	206350|Nitrosomonadales	M	MlaA lipoprotein	-	-	-	ko:K04754	-	-	-	-	ko00000	-	-	-	MlaA
k59_937660_1	1357400.HMPREF2086_01622	9.39e-24	106.0	2AGMT@1|root,316V3@2|Bacteria,1PY20@1224|Proteobacteria,42NND@68525|delta/epsilon subdivisions,2YMQB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	pgbB	-	-	-	-	-	-	-	-	-	-	-	PGBA_C,PQQ_2
k59_937660_2	990073.ATHU01000001_gene459	3.83e-17	80.5	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,42N0M@68525|delta/epsilon subdivisions,2YT9X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules	xerH	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_463934_1	387093.SUN_1492	7.13e-66	221.0	COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,42PHY@68525|delta/epsilon subdivisions,2YMBI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG0155 Sulfite reductase, beta subunit (hemoprotein)	-	-	1.7.7.1,1.8.7.1	ko:K00366,ko:K00392	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00531	R00790,R00859,R03600	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
k59_342081_1	1165841.SULAR_07410	1.1e-66	208.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,42MB9@68525|delta/epsilon subdivisions,2YMN0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	IQ	reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_1521640_1	709032.Sulku_0027	3.64e-82	254.0	COG2038@1|root,COG2038@2|Bacteria,1NZFH@1224|Proteobacteria,42NRQ@68525|delta/epsilon subdivisions,2YNQ9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	phosphoribosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DBI_PRT
k59_289020_1	1249480.B649_11215	3.58e-92	277.0	COG0760@1|root,COG0760@2|Bacteria,1N20M@1224|Proteobacteria,42SXW@68525|delta/epsilon subdivisions,2YPHS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase_2,SurA_N,SurA_N_3
k59_1112158_1	273121.WS1957	2.17e-91	278.0	COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,1MVC8@1224|Proteobacteria,42NJR@68525|delta/epsilon subdivisions,2YTAR@29547|Epsilonproteobacteria	68525|delta/epsilon subdivisions	L	HTH-like domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_Tnp_1,rve,rve_3
k59_289057_1	1123518.ARWI01000001_gene425	1.39e-27	109.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,1RQ1J@1236|Gammaproteobacteria,460UF@72273|Thiotrichales	72273|Thiotrichales	K	PFAM Response regulator receiver domain	-	-	-	ko:K07689	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
k59_820874_1	709032.Sulku_0724	4.74e-14	71.6	COG3608@1|root,COG3608@2|Bacteria,1Q5G3@1224|Proteobacteria,42MSH@68525|delta/epsilon subdivisions,2YMTA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	C-terminal domain of metallo-carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M99,Peptidase_M99_C
k59_820874_2	1537917.JU82_08735	8.06e-54	178.0	COG3034@1|root,COG3034@2|Bacteria,1N2B6@1224|Proteobacteria,42QS4@68525|delta/epsilon subdivisions,2YNYQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	ErfK YbiS YcfS YnhG family protein	pgp2	-	-	-	-	-	-	-	-	-	-	-	YkuD
k59_1521683_3	929558.SMGD1_1019	3.22e-60	187.0	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,42REF@68525|delta/epsilon subdivisions,2YP4V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
k59_1112217_1	666685.R2APBS1_2528	1.1e-69	219.0	2A1SN@1|root,30Q1C@2|Bacteria,1NXN6@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1404465_1	709032.Sulku_2168	1.48e-154	437.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,42M0Q@68525|delta/epsilon subdivisions,2YMXU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k59_749013_1	640081.Dsui_2313	4.63e-70	225.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,2VHVA@28216|Betaproteobacteria,2KVHT@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
k59_1812764_1	1121451.DESAM_20950	8.81e-06	48.9	COG1132@1|root,COG1132@2|Bacteria,1MVJD@1224|Proteobacteria,42PP5@68525|delta/epsilon subdivisions,2WMQR@28221|Deltaproteobacteria,2M8D9@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	PFAM ABC transporter related	-	-	-	ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1	-	-	ABC_membrane,ABC_tran
k59_1812764_2	1249480.B649_11260	4.47e-54	177.0	COG0249@1|root,COG0249@2|Bacteria,1Q1X0@1224|Proteobacteria,42UKG@68525|delta/epsilon subdivisions,2YQ3M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KLT	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_229617_1	1249480.B649_07455	4.02e-22	94.7	COG1315@1|root,COG1315@2|Bacteria,1R5P6@1224|Proteobacteria,42MAS@68525|delta/epsilon subdivisions,2YM7Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Flagellar Assembly Protein A	-	-	-	-	-	-	-	-	-	-	-	-	FapA
k59_403417_1	1537917.JU82_11870	2.8e-13	69.3	COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,42N08@68525|delta/epsilon subdivisions,2YMRG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	folylpolyglutamate synthase	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
k59_403417_2	709032.Sulku_0522	3.15e-116	362.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,42N8X@68525|delta/epsilon subdivisions,2YMGZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_1112302_1	1504981.KO116_1086	2.09e-07	52.4	COG2863@1|root,COG2863@2|Bacteria,1NGKI@1224|Proteobacteria,1SI6Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	PFAM Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
k59_820962_1	90813.JQMT01000001_gene54	1.23e-71	233.0	COG3174@1|root,COG3174@2|Bacteria,1RA19@1224|Proteobacteria,1S78D@1236|Gammaproteobacteria,463IM@72273|Thiotrichales	72273|Thiotrichales	S	Domain of unknown function (DUF4010)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010
k59_526411_1	1218074.BAXZ01000031_gene5047	1.65e-27	106.0	COG1028@1|root,COG1028@2|Bacteria,1MWCY@1224|Proteobacteria,2VRP6@28216|Betaproteobacteria,1K616@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_526411_2	392499.Swit_4617	2.17e-25	108.0	COG1232@1|root,COG1232@2|Bacteria,1QTUF@1224|Proteobacteria,2TYFK@28211|Alphaproteobacteria,2K8I8@204457|Sphingomonadales	204457|Sphingomonadales	H	NAD(P)-binding Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8
k59_1404562_2	709032.Sulku_2482	7.82e-121	351.0	28M05@1|root,2ZAF9@2|Bacteria,1MY5U@1224|Proteobacteria,42QPW@68525|delta/epsilon subdivisions,2YP0Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	General glycosylation pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_464152_1	929558.SMGD1_0383	3.21e-63	199.0	COG1413@1|root,COG1413@2|Bacteria,1RIZR@1224|Proteobacteria	1224|Proteobacteria	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
k59_464152_2	929558.SMGD1_0382	4.82e-148	422.0	COG1352@1|root,COG1352@2|Bacteria,1MVP3@1224|Proteobacteria,42SZX@68525|delta/epsilon subdivisions,2YTRV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Methyltransferase, chemotaxis proteins	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR
k59_820992_1	709032.Sulku_0061	3.38e-57	184.0	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,42M0U@68525|delta/epsilon subdivisions,2YNJV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	mechanosensitive ion channel	mscS	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
k59_342287_1	90814.KL370891_gene518	1.16e-100	303.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,1RNCP@1236|Gammaproteobacteria,45ZV4@72273|Thiotrichales	72273|Thiotrichales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
k59_342287_2	1504981.KO116_2270	3.1e-38	132.0	COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,1RP9H@1236|Gammaproteobacteria,1XJ8J@135619|Oceanospirillales	135619|Oceanospirillales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	1.10.2.2	ko:K00411	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,UCR_Fe-S_N
k59_526447_1	935863.AWZR01000001_gene1984	1.07e-09	59.7	COG0457@1|root,COG0745@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0745@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1S5TW@1236|Gammaproteobacteria,1X5PU@135614|Xanthomonadales	135614|Xanthomonadales	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8,Trans_reg_C
k59_1812841_1	709032.Sulku_0529	1.89e-119	361.0	COG0726@1|root,COG1649@1|root,COG0726@2|Bacteria,COG1649@2|Bacteria,1MWR2@1224|Proteobacteria,43AG1@68525|delta/epsilon subdivisions,2YT1V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Hypothetical glycosyl hydrolase family 13	-	-	-	ko:K11931	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000	-	-	-	GHL13,Polysacc_deac_1
k59_1641232_2	159087.Daro_1481	1.35e-54	174.0	2DZDN@1|root,32V7Z@2|Bacteria,1N0Y2@1224|Proteobacteria,2VX1Y@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1758159_1	1249480.B649_05555	5.88e-115	344.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,42NC6@68525|delta/epsilon subdivisions,2YMJV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
k59_821025_1	1163617.SCD_n00510	1.37e-63	196.0	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,2VRQ3@28216|Betaproteobacteria	28216|Betaproteobacteria	J	endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
k59_821025_2	1288494.EBAPG3_8220	3.86e-15	75.1	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,2VHE8@28216|Betaproteobacteria,372I7@32003|Nitrosomonadales	28216|Betaproteobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
k59_1112382_1	1121428.DESHY_150117___1	3.35e-64	204.0	COG1484@1|root,COG1484@2|Bacteria,1TPPI@1239|Firmicutes,24DKZ@186801|Clostridia,266XI@186807|Peptococcaceae	186801|Clostridia	L	PhoH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
k59_342329_1	1537917.JU82_05085	2.14e-46	154.0	COG4123@1|root,COG4123@2|Bacteria,1R0S2@1224|Proteobacteria,42UPG@68525|delta/epsilon subdivisions,2YPXV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,TehB
k59_342329_2	1537917.JU82_05080	3.96e-50	167.0	COG0144@1|root,COG0144@2|Bacteria,1MWPE@1224|Proteobacteria,42P2T@68525|delta/epsilon subdivisions,2YNNR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N
k59_1697429_1	387093.SUN_1075	1.38e-25	103.0	COG2220@1|root,COG2220@2|Bacteria,1MV20@1224|Proteobacteria,42QPP@68525|delta/epsilon subdivisions,2YP9R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
k59_1697429_2	1283284.AZUK01000002_gene2814	6.23e-44	145.0	COG0730@1|root,COG0730@2|Bacteria,1QDQW@1224|Proteobacteria,1SA4B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k59_49598_1	749222.Nitsa_2067	1.56e-32	120.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42PA1@68525|delta/epsilon subdivisions,2YNMR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_1344565_1	1249480.B649_04080	1.29e-80	241.0	COG0221@1|root,COG0221@2|Bacteria,1RA2F@1224|Proteobacteria,42MQB@68525|delta/epsilon subdivisions,2YM8X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
k59_106484_1	865861.AZSU01000008_gene667	3.18e-23	103.0	COG2199@1|root,COG3706@2|Bacteria,1V9Y7@1239|Firmicutes,24A8B@186801|Clostridia,36E8P@31979|Clostridiaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GGDEF,Pkinase,TPR_12,TPR_8
k59_1812898_1	709032.Sulku_1820	6.65e-96	284.0	COG0741@1|root,COG0741@2|Bacteria,1Q433@1224|Proteobacteria,432ZU@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	Transglycosylase SLT domain	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	SLT
k59_1758253_1	709032.Sulku_1361	3.05e-141	405.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,42M0C@68525|delta/epsilon subdivisions,2YM8W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
k59_1641354_1	1249480.B649_00655	2.5e-70	232.0	COG2604@1|root,COG2604@2|Bacteria,1R4P0@1224|Proteobacteria,42NB8@68525|delta/epsilon subdivisions,2YMMI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	hmm pf01973	pseE	-	-	-	-	-	-	-	-	-	-	-	MAF_flag10
k59_403626_1	1197906.CAJQ02000004_gene2994	2.94e-29	128.0	COG2304@1|root,COG2931@1|root,COG2304@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2VFEM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1344633_2	159087.Daro_3726	3.75e-80	245.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,2VI10@28216|Betaproteobacteria,2KVBM@206389|Rhodocyclales	206389|Rhodocyclales	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
k59_464313_1	1165841.SULAR_05948	2.92e-135	406.0	28N8G@1|root,2ZBCV@2|Bacteria,1NMB1@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1812945_1	387093.SUN_1202	7.44e-98	290.0	COG2048@1|root,COG2048@2|Bacteria,1RFWK@1224|Proteobacteria,43B86@68525|delta/epsilon subdivisions,2YT6P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Heterodisulfide reductase subunit B	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	CCG
k59_1838934_1	395494.Galf_2312	5.48e-88	276.0	COG1450@1|root,COG1450@2|Bacteria,1MVNC@1224|Proteobacteria,2VMT1@28216|Betaproteobacteria,44V3S@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	PFAM type II and III secretion system protein	exeD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N_2
k59_957123_1	709032.Sulku_2137	4.47e-84	267.0	COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,42YQC@68525|delta/epsilon subdivisions,2YRKN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k59_957123_2	1537917.JU82_02390	4.97e-09	56.6	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,42Q8J@68525|delta/epsilon subdivisions,2YMVG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	GM	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_2
k59_1252161_2	1537917.JU82_03245	6.74e-17	75.5	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,42SDX@68525|delta/epsilon subdivisions,2YP47@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
k59_604064_1	326298.Suden_1159	1.4e-35	130.0	COG0679@1|root,COG0679@2|Bacteria,1PHSS@1224|Proteobacteria,42M30@68525|delta/epsilon subdivisions,2YN5E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	auxin efflux carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
k59_604064_2	387093.SUN_1333	1.83e-30	108.0	2AJ7M@1|root,319SE@2|Bacteria,1Q3TQ@1224|Proteobacteria,42XTC@68525|delta/epsilon subdivisions,2YQQF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1017651_1	1249480.B649_10845	6.44e-142	409.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,42MEF@68525|delta/epsilon subdivisions,2YMMY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Aminotransferase	-	-	-	ko:K14261	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_1838979_1	159087.Daro_3828	2.46e-16	77.8	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,2KUC8@206389|Rhodocyclales	206389|Rhodocyclales	V	Protein export membrane protein	-	-	-	ko:K18902	-	M00698	-	-	ko00000,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_1838979_2	159087.Daro_3827	9.14e-58	193.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2VISZ@28216|Betaproteobacteria,2KV30@206389|Rhodocyclales	206389|Rhodocyclales	M	Outer membrane efflux protein	-	-	-	ko:K18903	-	M00698	-	-	ko00000,ko00002,ko01504,ko02000	1.B.17.3.3	-	-	OEP
k59_488076_1	946483.Cenrod_0512	2.2e-55	189.0	COG2244@1|root,COG2244@2|Bacteria,1NCUT@1224|Proteobacteria,2W57S@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_716739_1	472759.Nhal_1875	9.89e-21	91.3	COG1026@1|root,COG1026@2|Bacteria,1MVDJ@1224|Proteobacteria,1RYNI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Peptidase, M16	-	-	-	ko:K06972	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M16C_assoc,Peptidase_M16,Peptidase_M16_C
k59_716739_2	342610.Patl_2389	1.19e-23	102.0	COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,1RR50@1236|Gammaproteobacteria,2PZK6@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	protease with the C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
k59_251151_1	1168067.JAGP01000001_gene997	7.66e-39	142.0	COG0850@1|root,COG0850@2|Bacteria,1RHVN@1224|Proteobacteria,1S6K8@1236|Gammaproteobacteria,4612I@72273|Thiotrichales	72273|Thiotrichales	D	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization	minC	-	-	ko:K03610	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinC_C,MinC_N
k59_251151_2	317025.Tcr_1165	8.63e-34	123.0	COG2894@1|root,COG2894@2|Bacteria,1MUEU@1224|Proteobacteria,1RNJ0@1236|Gammaproteobacteria,45ZXI@72273|Thiotrichales	72273|Thiotrichales	D	Belongs to the ParA family	minD	-	-	ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
k59_251152_1	1249480.B649_05845	1.7e-43	147.0	COG4254@1|root,COG4254@2|Bacteria,1N739@1224|Proteobacteria,42VBI@68525|delta/epsilon subdivisions,2YQ2P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
k59_1305669_1	1159870.KB907784_gene2666	4.77e-76	240.0	COG1231@1|root,COG1231@2|Bacteria,1P3D9@1224|Proteobacteria,2VNQ6@28216|Betaproteobacteria,3T6ED@506|Alcaligenaceae	28216|Betaproteobacteria	E	Flavin containing amine oxidoreductase	-	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
k59_896904_1	709032.Sulku_1237	4.51e-45	149.0	COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,42QXP@68525|delta/epsilon subdivisions,2YPJE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
k59_896904_2	1249480.B649_06370	3.03e-104	310.0	COG1261@1|root,COG1261@2|Bacteria,1Q3ZV@1224|Proteobacteria,42Y1K@68525|delta/epsilon subdivisions,2YQRI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Chaperone for flagella basal body P-ring formation	flgA	-	-	ko:K02386	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	ChapFlgA
k59_309646_2	1249480.B649_04740	3.65e-141	407.0	29CAW@1|root,2ZZ9C@2|Bacteria,1Q5FH@1224|Proteobacteria,42Q2S@68525|delta/epsilon subdivisions,2YP18@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1430342_2	1122164.JHWF01000018_gene600	4.78e-07	51.2	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,1RM9M@1236|Gammaproteobacteria,1JD5Q@118969|Legionellales	118969|Legionellales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k59_780393_1	709032.Sulku_1443	8.69e-135	392.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,42N8U@68525|delta/epsilon subdivisions,2YMG9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0026	Citrate_synt
k59_1020775_2	652103.Rpdx1_2959	9.47e-15	72.0	2DTR2@1|root,33MC8@2|Bacteria,1NPT8@1224|Proteobacteria,2UKEK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1779318_1	207954.MED92_04849	1.61e-12	67.4	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XIJY@135619|Oceanospirillales	1236|Gammaproteobacteria	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CZB,EAL,GAF_2,GGDEF,PAS_3,PAS_4,PAS_9,Protoglobin
k59_1779318_2	944547.ABLL_2135	8.93e-11	62.4	COG0715@1|root,COG0834@1|root,COG4191@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG4191@2|Bacteria,1MXA3@1224|Proteobacteria,43AUG@68525|delta/epsilon subdivisions,2YN4Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,NMT1,SBP_bac_3
k59_1779324_1	644801.Psest_1811	3.91e-88	270.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,1RMCS@1236|Gammaproteobacteria,1Z39J@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	spsC	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
k59_668005_1	987059.RBXJA2T_05678	5.63e-54	181.0	COG2327@1|root,COG2327@2|Bacteria,1RBBM@1224|Proteobacteria,2VV5P@28216|Betaproteobacteria,1KNVX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Polysaccharide pyruvyl transferase	-	-	-	ko:K16563	-	-	-	-	ko00000	-	-	-	PS_pyruv_trans
k59_1368533_1	1537917.JU82_04420	3.7e-95	283.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,42NEA@68525|delta/epsilon subdivisions,2YN5P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
k59_959540_1	1165841.SULAR_03642	2.18e-115	354.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,42MPZ@68525|delta/epsilon subdivisions,2YM8C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k59_193167_1	265072.Mfla_0652	1.83e-15	76.3	COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1MUI0@1224|Proteobacteria,2VICS@28216|Betaproteobacteria,2KKMV@206350|Nitrosomonadales	206350|Nitrosomonadales	H	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme	cysG	-	1.3.1.76,2.1.1.107,4.99.1.4	ko:K02302	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03194,R03947	RC00003,RC00871,RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase
k59_193167_2	1434929.X946_3452	8.7e-37	138.0	COG0243@1|root,COG0369@1|root,COG0243@2|Bacteria,COG0369@2|Bacteria,1NS3T@1224|Proteobacteria,2VI9C@28216|Betaproteobacteria,1KFCW@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.8.1.2	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_1,Flavodoxin_1,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NAD_binding_1
k59_1720895_2	1249480.B649_04990	7.68e-55	175.0	COG0735@1|root,COG0735@2|Bacteria,1N0HW@1224|Proteobacteria,43B75@68525|delta/epsilon subdivisions,2YPV3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Belongs to the Fur family	-	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
k59_74233_2	1249480.B649_03160	7.2e-60	187.0	COG1331@1|root,COG1331@2|Bacteria,1N55I@1224|Proteobacteria,42VTZ@68525|delta/epsilon subdivisions,2YQJ6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Highly conserved protein containing a thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH
k59_428916_2	1249480.B649_10795	8.89e-217	605.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,42NKY@68525|delta/epsilon subdivisions,2YN43@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
k59_1430426_1	1249480.B649_00225	5.1e-25	98.6	COG0778@1|root,COG0778@2|Bacteria,1N95W@1224|Proteobacteria,42RYF@68525|delta/epsilon subdivisions,2YP3N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Nitroreductase	frxA	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_1430426_2	1249480.B649_00230	2.51e-43	149.0	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,42M0U@68525|delta/epsilon subdivisions,2YNJV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	mechanosensitive ion channel	mscS	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
k59_606768_1	709032.Sulku_0335	1.43e-73	241.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,42N34@68525|delta/epsilon subdivisions,2YMFS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_C
k59_1192047_1	1165841.SULAR_03048	5.7e-73	233.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2YMN1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DEAD box helicase family	deaD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
k59_899280_2	1537917.JU82_09870	2.78e-119	342.0	2BM55@1|root,32FNN@2|Bacteria,1Q0P6@1224|Proteobacteria,42SB7@68525|delta/epsilon subdivisions,2YPGR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	DNA replication regulator	hobA	-	-	-	-	-	-	-	-	-	-	-	HobA
k59_899280_3	1537917.JU82_09865	5.26e-10	58.2	COG0470@1|root,COG0470@2|Bacteria,1R9U1@1224|Proteobacteria,42R45@68525|delta/epsilon subdivisions,2YPZZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA polymerase III	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
k59_550966_1	1101190.ARWB01000001_gene3664	4.71e-07	50.4	COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,2U76C@28211|Alphaproteobacteria,36YF0@31993|Methylocystaceae	28211|Alphaproteobacteria	E	Shikimate kinase	aroK	GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
k59_550966_2	349521.HCH_06315	6.3e-79	241.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,1RN09@1236|Gammaproteobacteria,1XJ5P@135619|Oceanospirillales	135619|Oceanospirillales	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
k59_1720949_1	1249480.B649_04980	2.81e-40	145.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,43DAE@68525|delta/epsilon subdivisions,2YTHG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG2199 FOG GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_550973_1	709032.Sulku_0603	1.65e-88	263.0	2BM55@1|root,32FNN@2|Bacteria,1Q0P6@1224|Proteobacteria,42SB7@68525|delta/epsilon subdivisions,2YPGR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	DNA replication regulator	hobA	-	-	-	-	-	-	-	-	-	-	-	HobA
k59_193213_1	709032.Sulku_0325	1.64e-47	172.0	COG2198@1|root,COG2198@2|Bacteria,1PCKH@1224|Proteobacteria,42W9Z@68525|delta/epsilon subdivisions,2YQ6K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_899289_1	317025.Tcr_1606	2.97e-70	226.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPN9@1236|Gammaproteobacteria,45ZQM@72273|Thiotrichales	72273|Thiotrichales	S	ABC transporter, ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
k59_780519_1	159087.Daro_2913	1.06e-103	301.0	COG3749@1|root,COG3749@2|Bacteria,1RJR9@1224|Proteobacteria,2VSQB@28216|Betaproteobacteria,2KWPT@206389|Rhodocyclales	206389|Rhodocyclales	S	Bacterial protein of unknown function (DUF934)	-	-	-	-	-	-	-	-	-	-	-	-	DUF934
k59_780519_2	1304883.KI912532_gene2008	4.48e-27	104.0	COG0175@1|root,COG0175@2|Bacteria,1MXUR@1224|Proteobacteria,2VIR0@28216|Betaproteobacteria,2KU98@206389|Rhodocyclales	206389|Rhodocyclales	EH	Reduction of activated sulfate into sulfite	cysH	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
k59_1368597_1	944547.ABLL_0648	1.66e-50	177.0	COG0579@1|root,COG0579@2|Bacteria,1MUCC@1224|Proteobacteria,42M2Q@68525|delta/epsilon subdivisions,2YMYG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Malate quinone- oxidoreductase	mqo	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.1.5.4	ko:K00116	ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00009,M00011	R00360,R00361,R01257	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0086	Mqo
k59_1255169_1	709032.Sulku_2375	2.29e-13	66.6	COG2203@1|root,COG2203@2|Bacteria,1NT6X@1224|Proteobacteria,42XRB@68525|delta/epsilon subdivisions,2YRTW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF
k59_1255169_2	1249480.B649_11245	8.39e-94	276.0	COG2203@1|root,COG2203@2|Bacteria,1R0Y5@1224|Proteobacteria,42NT7@68525|delta/epsilon subdivisions,2YRW5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF
k59_780533_2	159087.Daro_3515	1.47e-55	191.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,2VIB1@28216|Betaproteobacteria,2KUYS@206389|Rhodocyclales	206389|Rhodocyclales	C	nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC	napA	-	-	ko:K02567	ko00910,ko01120,map00910,map01120	M00529,M00530	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_551003_1	1537917.JU82_09360	2.8e-102	298.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_551003_2	929558.SMGD1_2362	1.15e-16	80.1	COG2829@1|root,COG2829@2|Bacteria,1PC8I@1224|Proteobacteria,42R3P@68525|delta/epsilon subdivisions,2YPBM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COGs COG2829 Outer membrane phospholipase A	-	-	3.1.1.32,3.1.1.4	ko:K01058	ko00564,ko00565,ko00590,ko00591,ko00592,ko01100,ko01110,map00564,map00565,map00590,map00591,map00592,map01100,map01110	-	R01315,R01316,R01317,R02053,R02054,R04034,R07064,R07379,R07387,R07859,R07860	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko01000	-	-	-	PLA1
k59_309745_1	641107.CDLVIII_0709	7.61e-65	224.0	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,2490U@186801|Clostridia,36EG3@31979|Clostridiaceae	186801|Clostridia	Q	TIGRFAM amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,NAD_binding_4,PP-binding,Thioesterase
k59_1662738_1	525898.Sdel_1174	1.04e-45	155.0	COG0428@1|root,COG0428@2|Bacteria,1MWEZ@1224|Proteobacteria,42NT2@68525|delta/epsilon subdivisions,2YMWF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Mediates zinc uptake. May also transport other divalent cations	zupT	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
k59_1662738_2	709032.Sulku_0064	2.58e-45	147.0	COG0607@1|root,COG0607@2|Bacteria,1Q1NN@1224|Proteobacteria,42U2F@68525|delta/epsilon subdivisions,2YQ1E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1548305_1	1165841.SULAR_05678	6.54e-61	194.0	COG2078@1|root,COG2078@2|Bacteria,1RJP4@1224|Proteobacteria,42SBG@68525|delta/epsilon subdivisions,2YP68@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM AMMECR1 domain protein	-	-	-	ko:K09141	-	-	-	-	ko00000	-	-	-	AMMECR1
k59_1076252_1	717773.Thicy_0253	9.49e-72	242.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,45ZWV@72273|Thiotrichales	72273|Thiotrichales	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_138675_1	159087.Daro_1228	5.71e-60	190.0	COG2885@1|root,COG2885@2|Bacteria,1N6EM@1224|Proteobacteria,2VM27@28216|Betaproteobacteria,2KW20@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA
k59_1779452_1	1537917.JU82_03460	6.28e-45	150.0	COG0560@1|root,COG0560@2|Bacteria,1MWA3@1224|Proteobacteria,42NIR@68525|delta/epsilon subdivisions,2YNHV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	phosphoserine phosphatase	serB	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD,Hydrolase
k59_1779452_2	709032.Sulku_1885	3.97e-49	159.0	2AK8C@1|root,31AYM@2|Bacteria,1Q6J3@1224|Proteobacteria,43398@68525|delta/epsilon subdivisions,2YSRM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1662783_1	709032.Sulku_2169	2.21e-52	173.0	COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,42N17@68525|delta/epsilon subdivisions,2YMV6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
k59_193306_1	1008459.TASI_0570	1.82e-29	107.0	COG0254@1|root,COG0254@2|Bacteria,1MZ4D@1224|Proteobacteria,2VWI5@28216|Betaproteobacteria,3T487@506|Alcaligenaceae	28216|Betaproteobacteria	J	there appears to be two types of ribosomal proteins L31 in bacterial genomes	rpmE2	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
k59_1548383_1	1249480.B649_03280	1.44e-166	491.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,42MN5@68525|delta/epsilon subdivisions,2YN0Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	DUF294,GlnD_UR_UTase,HD,NTP_transf_2
k59_606913_1	1165841.SULAR_00520	1.52e-18	79.7	COG1846@1|root,COG1846@2|Bacteria,1Q5M6@1224|Proteobacteria,431G7@68525|delta/epsilon subdivisions,2YS5F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_606913_2	1165841.SULAR_00515	1.42e-45	148.0	2C948@1|root,32SAI@2|Bacteria,1MZC2@1224|Proteobacteria,42U40@68525|delta/epsilon subdivisions,2YPYK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Putative mono-oxygenase ydhR	-	-	-	-	-	-	-	-	-	-	-	-	ydhR
k59_1368689_1	1123514.KB905901_gene121	1.69e-32	125.0	COG1752@1|root,COG1752@2|Bacteria,1MUI6@1224|Proteobacteria,1RN0G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
k59_551106_1	159087.Daro_3725	7.4e-64	212.0	COG0699@1|root,COG0699@2|Bacteria,1MXBK@1224|Proteobacteria,2VKA1@28216|Betaproteobacteria,2KUHM@206389|Rhodocyclales	206389|Rhodocyclales	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
k59_138742_1	1304883.KI912532_gene1682	6.19e-73	228.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,2VHBG@28216|Betaproteobacteria,2KV9X@206389|Rhodocyclales	206389|Rhodocyclales	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
k59_138742_2	159087.Daro_3365	5.36e-43	152.0	COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,2VH2B@28216|Betaproteobacteria,2KVS2@206389|Rhodocyclales	206389|Rhodocyclales	V	extrusion protein MatE	norM	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
k59_1548400_1	1537917.JU82_06335	1.09e-88	271.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,42UPM@68525|delta/epsilon subdivisions,2YRIE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL
k59_1779502_1	387093.SUN_1317	1.87e-50	189.0	COG2703@1|root,COG5001@1|root,COG5002@1|root,COG2703@2|Bacteria,COG5001@2|Bacteria,COG5002@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YN16@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	GGDEF EAL family protein	-	-	-	-	-	-	-	-	-	-	-	-	CZB,EAL,GGDEF,Hemerythrin,PAS_4,PAS_9
k59_369077_1	886379.AEWI01000179_gene1529	2.04e-27	107.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_4
k59_1255289_1	929558.SMGD1_2397	9.85e-15	73.2	COG0642@1|root,COG4753@1|root,COG2205@2|Bacteria,COG4753@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	3.1.3.3,4.6.1.1	ko:K01768,ko:K07315	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	EAL,Guanylate_cyc,HATPase_c,HisKA,Pkinase,Response_reg,SpoIIE
k59_1021071_1	709032.Sulku_2531	3.44e-78	239.0	COG2755@1|root,COG2755@2|Bacteria,1RHDZ@1224|Proteobacteria,42SMX@68525|delta/epsilon subdivisions,2YPZI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
k59_1021071_2	1249480.B649_11725	2.21e-16	78.2	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,42NBJ@68525|delta/epsilon subdivisions,2YMTY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Mg chelatase-related protein	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
k59_668250_1	1249480.B649_10875	3.33e-89	266.0	COG1385@1|root,COG1385@2|Bacteria,1QDSD@1224|Proteobacteria,42S1W@68525|delta/epsilon subdivisions,2YP9M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
k59_1021088_1	1249480.B649_06960	1.85e-82	254.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,42M3C@68525|delta/epsilon subdivisions,2YNGF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
k59_959727_1	159087.Daro_3091	2.66e-55	177.0	COG5501@1|root,COG5501@2|Bacteria,1RH4J@1224|Proteobacteria,2VT8I@28216|Betaproteobacteria,2KWNG@206389|Rhodocyclales	206389|Rhodocyclales	S	Sulfur oxidation protein SoxY	soxY	-	-	ko:K17226	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxY
k59_1137041_1	159087.Daro_3483	1.1e-110	321.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,2VIGU@28216|Betaproteobacteria,2KVMH@206389|Rhodocyclales	206389|Rhodocyclales	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
k59_1137041_2	159087.Daro_3484	1.44e-34	120.0	COG2967@1|root,COG2967@2|Bacteria,1MZ2Z@1224|Proteobacteria,2VSPE@28216|Betaproteobacteria,2KWM4@206389|Rhodocyclales	206389|Rhodocyclales	P	protein affecting Mg2 Co2 transport	apaG	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
k59_922170_1	1537917.JU82_09440	3.15e-106	309.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,42SPZ@68525|delta/epsilon subdivisions,2YMS1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	fdhF	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_328431_1	1249480.B649_01510	4.06e-64	198.0	COG1714@1|root,COG1714@2|Bacteria,1N7R6@1224|Proteobacteria,42U2T@68525|delta/epsilon subdivisions,2YPV6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
k59_328431_2	1537917.JU82_03850	2.92e-16	78.2	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,42N34@68525|delta/epsilon subdivisions,2YMFS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_C
k59_1575278_1	1249480.B649_00240	2.24e-23	93.6	COG1714@1|root,COG1714@2|Bacteria,1N7R6@1224|Proteobacteria,42UXC@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
k59_1052220_2	159087.Daro_4198	2.05e-52	171.0	COG2913@1|root,COG2913@2|Bacteria,1RDAX@1224|Proteobacteria,2VTWJ@28216|Betaproteobacteria,2KYXQ@206389|Rhodocyclales	206389|Rhodocyclales	J	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_40801_1	640512.BC1003_4748	3.29e-116	356.0	COG1387@1|root,COG1387@2|Bacteria,1MYXV@1224|Proteobacteria,2VJIQ@28216|Betaproteobacteria,1K4RW@119060|Burkholderiaceae	28216|Betaproteobacteria	L	DNA polymerase	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
k59_1102169_1	709032.Sulku_0786	1.59e-112	348.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,42MKB@68525|delta/epsilon subdivisions,2YMIZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
k59_1803958_1	1249480.B649_09615	1.04e-112	340.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,42M4S@68525|delta/epsilon subdivisions,2YM8Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	-	-	1.12.5.1	ko:K05922	-	-	-	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
k59_1687484_1	375286.mma_0197	8.22e-43	154.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,2VK0Y@28216|Betaproteobacteria,47326@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
k59_1511422_1	709032.Sulku_0954	1.98e-85	263.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,42M3C@68525|delta/epsilon subdivisions,2YMHJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
k59_1334488_1	159087.Daro_3552	1.46e-120	353.0	COG0027@1|root,COG0027@2|Bacteria,1N3KA@1224|Proteobacteria,2VH4M@28216|Betaproteobacteria,2KV39@206389|Rhodocyclales	206389|Rhodocyclales	F	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate	purT	-	2.1.2.2	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp,Epimerase
k59_990436_1	380703.AHA_0178	1.51e-11	60.5	2ES0Z@1|root,33JK1@2|Bacteria,1NHKR@1224|Proteobacteria,1SI94@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	VC0074	-	-	-	-	-	-	-	-	-	-	-	-
k59_990436_2	1537917.JU82_11405	3.06e-78	235.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,42RNC@68525|delta/epsilon subdivisions,2YPBE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL,UPF0547
k59_990436_3	1249480.B649_11410	7.35e-78	246.0	COG3437@1|root,COG4191@1|root,COG3437@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43DAR@68525|delta/epsilon subdivisions,2YTHT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HD
k59_698806_1	1249480.B649_09055	5.16e-39	136.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,42QV4@68525|delta/epsilon subdivisions,2YMTK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
k59_698806_2	1249480.B649_09050	4.26e-76	248.0	COG0457@1|root,COG0457@2|Bacteria,1QV15@1224|Proteobacteria,42NKI@68525|delta/epsilon subdivisions,2YMKG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	COG0457 FOG TPR repeat	pflB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_6,TPR_8
k59_277845_2	857087.Metme_0999	3.06e-72	243.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1RNST@1236|Gammaproteobacteria,1XGZ1@135618|Methylococcales	135618|Methylococcales	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
k59_1579324_1	1445613.JALM01000006_gene584	1.92e-05	45.8	COG0509@1|root,COG0509@2|Bacteria,2IKN2@201174|Actinobacteria,4E4H7@85010|Pseudonocardiales	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
k59_1579324_2	90814.KL370891_gene1318	8.1e-90	271.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RPT8@1236|Gammaproteobacteria,460ZA@72273|Thiotrichales	72273|Thiotrichales	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_1748937_1	1249480.B649_02775	1.6e-132	377.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,42MG4@68525|delta/epsilon subdivisions,2YME4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	response regulator	cprR	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_222057_2	395494.Galf_0085	3.05e-81	253.0	COG2206@1|root,COG2206@2|Bacteria,1R53C@1224|Proteobacteria,2VNCZ@28216|Betaproteobacteria,44W2G@713636|Nitrosomonadales	28216|Betaproteobacteria	T	PFAM metal-dependent phosphohydrolase HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
k59_97591_1	1268072.PSAB_03585	4.54e-59	195.0	COG1250@1|root,COG1250@2|Bacteria,1V111@1239|Firmicutes,4HU3H@91061|Bacilli,271JM@186822|Paenibacillaceae	91061|Bacilli	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
k59_1687601_1	709032.Sulku_0279	5.64e-90	285.0	COG0457@1|root,COG0457@2|Bacteria,1QV1A@1224|Proteobacteria,42MIW@68525|delta/epsilon subdivisions,2YMDB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Paralysed flagella protein	pflA	-	-	-	-	-	-	-	-	-	-	-	TPR_21,TPR_6,TPR_8,YfiO
k59_1334615_1	768670.Calni_1641	8.59e-34	127.0	COG1543@1|root,COG1543@2|Bacteria,2GET7@200930|Deferribacteres	200930|Deferribacteres	G	Domain of unknown function (DUF1957)	-	-	2.4.1.18	ko:K16149	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000	-	GH57	-	DUF1957,Glyco_hydro_57
k59_1511511_1	159087.Daro_0290	1.9e-61	196.0	COG0115@1|root,COG0115@2|Bacteria,1MVAT@1224|Proteobacteria,2VIVK@28216|Betaproteobacteria,2KVN6@206389|Rhodocyclales	206389|Rhodocyclales	EH	Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase	-	-	2.6.1.21	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	-	R01148,R01582,R02459,R02851,R02924,R05053	RC00006,RC00008,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4
k59_1511511_2	159087.Daro_0289	1.75e-44	144.0	COG2921@1|root,COG2921@2|Bacteria,1RGV5@1224|Proteobacteria,2VTY5@28216|Betaproteobacteria,2KWZM@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the UPF0250 family	-	-	-	ko:K09158	-	-	-	-	ko00000	-	-	-	DUF493
k59_635711_1	748247.AZKH_3660	3.21e-14	72.4	COG0642@1|root,COG2205@2|Bacteria,1N1Z2@1224|Proteobacteria,2VPAI@28216|Betaproteobacteria,2KVP3@206389|Rhodocyclales	206389|Rhodocyclales	T	Two-component sensor kinase N-terminal	-	-	2.7.13.3	ko:K07649	ko02020,map02020	M00457	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	2CSK_N,HATPase_c,HisKA
k59_635711_2	1121035.AUCH01000013_gene3172	6.74e-27	108.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,2VMTN@28216|Betaproteobacteria,2KVH2@206389|Rhodocyclales	206389|Rhodocyclales	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	-	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,iPGM_N
k59_990622_2	709032.Sulku_1289	6.25e-153	441.0	COG2710@1|root,COG2710@2|Bacteria,1MWAJ@1224|Proteobacteria,42M5T@68525|delta/epsilon subdivisions,2YNN6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	cofactor biosynthesis protein NifE	-	-	-	ko:K02587	-	-	-	-	ko00000	-	-	-	Oxidored_nitro
k59_40956_1	1249480.B649_03325	1.97e-10	60.5	COG1807@1|root,COG1807@2|Bacteria,1Q901@1224|Proteobacteria,42MGX@68525|delta/epsilon subdivisions,2YNER@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
k59_580450_1	709032.Sulku_0235	1.29e-120	348.0	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,42M3Y@68525|delta/epsilon subdivisions,2YMD5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
k59_222101_2	1165841.SULAR_00135	1.14e-119	363.0	COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,42MY0@68525|delta/epsilon subdivisions,2YMT1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
k59_1052408_2	391615.ABSJ01000030_gene772	1.51e-13	68.2	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,1S8RS@1236|Gammaproteobacteria,1J6H1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Biopolymer transport protein	tolR	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032153,GO:0042221,GO:0042493,GO:0042886,GO:0042891,GO:0043213,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
k59_1394851_1	7460.GB49253-PA	5.41e-70	220.0	COG1208@1|root,KOG1322@2759|Eukaryota,3ANJC@33154|Opisthokonta,3C1B3@33208|Metazoa	33208|Metazoa	M	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
k59_1749028_1	709032.Sulku_1928	1.11e-152	446.0	28J7E@1|root,2Z92U@2|Bacteria,1NAE1@1224|Proteobacteria,42P08@68525|delta/epsilon subdivisions,2YNTD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
k59_810769_1	1249480.B649_03830	2.84e-57	186.0	COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,42QG8@68525|delta/epsilon subdivisions,2YNS2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Succinylglutamate desuccinylase	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
k59_739719_1	1537917.JU82_06640	2.25e-136	403.0	COG0668@1|root,COG0668@2|Bacteria,1PMY3@1224|Proteobacteria,42M4K@68525|delta/epsilon subdivisions,2YMAQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
k59_1218721_1	1537917.JU82_02950	8.35e-126	366.0	COG1140@1|root,COG1140@2|Bacteria,1MW9Q@1224|Proteobacteria,42NWV@68525|delta/epsilon subdivisions,2YMN9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K17051	-	-	-	-	ko00000,ko02000	5.A.3.8	-	-	Fer4_11
k59_1460572_1	159087.Daro_3081	2.49e-86	264.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,2VH9C@28216|Betaproteobacteria,2KVN9@206389|Rhodocyclales	206389|Rhodocyclales	S	Permease YjgP YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_332077_1	1089439.KB902240_gene707	4.46e-27	104.0	COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,1RNJP@1236|Gammaproteobacteria,460M0@72273|Thiotrichales	72273|Thiotrichales	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
k59_332077_2	1123400.KB904754_gene1018	5.74e-67	226.0	COG1333@1|root,COG1333@2|Bacteria,1N6XE@1224|Proteobacteria,1RXXZ@1236|Gammaproteobacteria,46045@72273|Thiotrichales	72273|Thiotrichales	O	Cytochrome c-type biogenesis protein Ccs1 ResB	-	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
k59_454474_1	1165841.SULAR_09634	1.03e-25	101.0	COG3531@1|root,COG3531@2|Bacteria,1RIN9@1224|Proteobacteria,42ZIN@68525|delta/epsilon subdivisions,2YRQ0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Thioredoxin	-	-	-	ko:K07396	-	-	-	-	ko00000	-	-	-	Thioredoxin_5
k59_454474_2	742725.HMPREF9450_01363	6.98e-56	184.0	COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,4NMAJ@976|Bacteroidetes,2FNTE@200643|Bacteroidia	976|Bacteroidetes	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
k59_454474_4	1165841.SULAR_07665	2.44e-73	223.0	COG2190@1|root,COG2190@2|Bacteria,1MWIQ@1224|Proteobacteria	1224|Proteobacteria	G	pts system	crr	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006109,GO:0006793,GO:0006796,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0009401,GO:0009892,GO:0009898,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019222,GO:0019897,GO:0019898,GO:0031234,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045912,GO:0048519,GO:0050789,GO:0051179,GO:0051234,GO:0065007,GO:0071702,GO:0071944,GO:0080090,GO:0098552,GO:0098562	-	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	M00265,M00266,M00268,M00270,M00272,M00303,M00806	R02738,R02780,R04111,R04394,R05132,R08559	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.1	-	e_coli_core.b2417,iAF1260.b2417,iAPECO1_1312.APECO1_4128,iB21_1397.B21_02278,iBWG_1329.BWG_2179,iE2348C_1286.E2348C_2603,iEC042_1314.EC042_2626,iEC55989_1330.EC55989_2707,iECABU_c1320.ECABU_c27380,iECBD_1354.ECBD_1264,iECB_1328.ECB_02317,iECDH10B_1368.ECDH10B_2582,iECDH1ME8569_1439.ECDH1ME8569_2351,iECD_1391.ECD_02317,iECED1_1282.ECED1_2861,iECH74115_1262.ECH74115_3648,iECIAI1_1343.ECIAI1_2475,iECIAI39_1322.ECIAI39_2563,iECNA114_1301.ECNA114_2494,iECO103_1326.ECO103_2936,iECO111_1330.ECO111_3147,iECO26_1355.ECO26_3470,iECOK1_1307.ECOK1_2734,iECS88_1305.ECS88_2607,iECSE_1348.ECSE_2708,iECSF_1327.ECSF_2281,iECSP_1301.ECSP_3365,iECUMN_1333.ECUMN_2739,iECW_1372.ECW_m2646,iEKO11_1354.EKO11_1311,iETEC_1333.ETEC_2530,iEcDH1_1363.EcDH1_1244,iEcE24377_1341.EcE24377A_2704,iEcHS_1320.EcHS_A2552,iEcSMS35_1347.EcSMS35_2572,iEcolC_1368.EcolC_1261,iG2583_1286.G2583_2949,iJO1366.b2417,iJR904.b2417,iLF82_1304.LF82_0357,iNRG857_1313.NRG857_12120,iSFV_1184.SFV_2469,iSF_1195.SF2472,iSFxv_1172.SFxv_2721,iSSON_1240.SSON_2506,iS_1188.S2618,iUMN146_1321.UM146_04535,iUMNK88_1353.UMNK88_3019,iUTI89_1310.UTI89_C2751,iWFL_1372.ECW_m2646,iY75_1357.Y75_RS12665,ic_1306.c2952	PTS_EIIA_1
k59_454474_5	1165841.SULAR_07670	6.79e-80	248.0	COG1820@1|root,COG1820@2|Bacteria,1MW8Y@1224|Proteobacteria,42ZSN@68525|delta/epsilon subdivisions	1224|Proteobacteria	G	Amidohydrolase family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k59_1804168_1	55601.VANGNB10_cI0355	2.83e-32	128.0	COG2199@1|root,COG2199@2|Bacteria,1NV1F@1224|Proteobacteria,1T1UD@1236|Gammaproteobacteria,1Y2EY@135623|Vibrionales	135623|Vibrionales	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_9,dCache_1
k59_864864_1	944547.ABLL_2296	2.58e-24	100.0	COG3660@1|root,COG3660@2|Bacteria,1RC47@1224|Proteobacteria,42R32@68525|delta/epsilon subdivisions,2YNVT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Mitochondrial fission ELM1	-	-	-	ko:K07276	-	-	-	-	ko00000	-	-	-	Mito_fiss_Elm1
k59_864864_2	314254.OA2633_13800	6.03e-10	62.4	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,2TS2H@28211|Alphaproteobacteria,43WBC@69657|Hyphomonadaceae	28211|Alphaproteobacteria	M	COG1560 Lauroyl myristoyl acyltransferase	msbB	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
k59_1804186_1	709032.Sulku_0431	1.9e-85	259.0	COG0287@1|root,COG0287@2|Bacteria,1QTZA@1224|Proteobacteria,42MH0@68525|delta/epsilon subdivisions,2YMHS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
k59_1165347_1	1485544.JQKP01000020_gene69	3.1e-39	141.0	COG2307@1|root,COG2307@2|Bacteria,1MVZK@1224|Proteobacteria,2VIB5@28216|Betaproteobacteria,44WI8@713636|Nitrosomonadales	28216|Betaproteobacteria	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
k59_454524_1	944547.ABLL_1810	2.79e-34	120.0	COG0298@1|root,COG0298@2|Bacteria,1N76Y@1224|Proteobacteria,42X24@68525|delta/epsilon subdivisions,2YPV9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	hydrogenase assembly chaperone HypC	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
k59_454524_2	63737.Npun_R0360	4.34e-08	55.1	COG0409@1|root,COG0409@2|Bacteria,1G0NJ@1117|Cyanobacteria,1HKUA@1161|Nostocales	1117|Cyanobacteria	O	TIGRFAM hydrogenase expression formation protein HypD	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
k59_635804_1	1123393.KB891316_gene1282	2.35e-104	320.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k59_1579491_1	709032.Sulku_1407	6.13e-07	47.8	COG0762@1|root,COG0762@2|Bacteria,1QDB9@1224|Proteobacteria,42VCU@68525|delta/epsilon subdivisions,2YQ8B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
k59_1579491_2	1249480.B649_05815	1.76e-104	313.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,42NHA@68525|delta/epsilon subdivisions,2YMYU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX1	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
k59_1284559_1	1094980.Mpsy_2042	1.13e-08	62.4	arCOG02348@1|root,arCOG07605@1|root,arCOG02348@2157|Archaea,arCOG07605@2157|Archaea,2XX6C@28890|Euryarchaeota,2NAQA@224756|Methanomicrobia	224756|Methanomicrobia	T	His Kinase A (phospho-acceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_517728_1	159087.Daro_3777	7.28e-86	272.0	28J5I@1|root,2Z91C@2|Bacteria,1QVI2@1224|Proteobacteria,2VN9N@28216|Betaproteobacteria,2KV6Q@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF1302)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1302
k59_1394976_1	1537917.JU82_09645	8.21e-72	228.0	COG0535@1|root,COG0535@2|Bacteria,1PHAQ@1224|Proteobacteria,42QIE@68525|delta/epsilon subdivisions,2YNUJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
k59_278166_1	583345.Mmol_0338	5.4e-141	434.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,2VHF3@28216|Betaproteobacteria,2KM9G@206350|Nitrosomonadales	206350|Nitrosomonadales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_1579531_1	1165841.SULAR_09629	5.03e-100	302.0	COG0025@1|root,COG0025@2|Bacteria,1QHRZ@1224|Proteobacteria,42RU2@68525|delta/epsilon subdivisions,2YPAV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0025 NhaP-type Na H and K H	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	GGDEF,Na_H_Exchanger
k59_517743_1	1458275.AZ34_11050	2e-46	154.0	COG0664@1|root,COG0664@2|Bacteria,1R64V@1224|Proteobacteria,2VJXN@28216|Betaproteobacteria,4ACEI@80864|Comamonadaceae	28216|Betaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
k59_517743_2	296591.Bpro_2798	8.51e-27	106.0	COG2823@1|root,COG2823@2|Bacteria,1N42J@1224|Proteobacteria,2VK5B@28216|Betaproteobacteria,4AHC6@80864|Comamonadaceae	28216|Betaproteobacteria	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	BON,Cytidylate_kin2
k59_278178_1	709032.Sulku_0306	1.31e-148	427.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,42NF0@68525|delta/epsilon subdivisions,2YMRR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3
k59_278178_2	709032.Sulku_0307	6.2e-33	124.0	COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,42MRJ@68525|delta/epsilon subdivisions,2YMF2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,UPF0004
k59_1218830_1	1537917.JU82_11560	1.19e-54	182.0	COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,42N49@68525|delta/epsilon subdivisions,2YND2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA
k59_1511739_1	1304883.KI912532_gene325	4.97e-88	277.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,2VH74@28216|Betaproteobacteria,2KVA2@206389|Rhodocyclales	206389|Rhodocyclales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_739837_2	1249480.B649_00450	0.000939	39.3	COG0268@1|root,COG0268@2|Bacteria,1NITA@1224|Proteobacteria,42V4U@68525|delta/epsilon subdivisions,2YPUG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
k59_810928_1	1380380.JIAX01000008_gene1899	1.84e-30	117.0	COG1376@1|root,COG1376@2|Bacteria,1MUAB@1224|Proteobacteria,2TTXM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
k59_1630541_2	1249480.B649_11050	2.08e-90	265.0	COG1144@1|root,COG1144@2|Bacteria,1NM08@1224|Proteobacteria,42SV1@68525|delta/epsilon subdivisions,2YPG8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	pyruvate ferredoxin oxidoreductase	porD	-	1.2.7.1	ko:K00171	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_10,Fer4_21
k59_1052595_1	1537917.JU82_02705	2.33e-92	284.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,42M3N@68525|delta/epsilon subdivisions,2YMQ3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
k59_278198_1	243365.CV_0943	1.64e-91	271.0	COG0852@1|root,COG0852@2|Bacteria,1MX4B@1224|Proteobacteria,2VHHV@28216|Betaproteobacteria,2KPCU@206351|Neisseriales	206351|Neisseriales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
k59_635883_1	1249480.B649_00685	2.16e-64	208.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,Methyltransf_14
k59_1749170_1	1165841.SULAR_03757	7.92e-119	352.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2YNK4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
k59_699100_1	1304883.KI912532_gene2121	5.78e-87	285.0	COG2911@1|root,COG2911@2|Bacteria,1QWGG@1224|Proteobacteria,2WGYX@28216|Betaproteobacteria,2KZX3@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
k59_1395021_1	1537917.JU82_00200	1.69e-37	127.0	2AK43@1|root,31ATX@2|Bacteria,1Q64B@1224|Proteobacteria,432D7@68525|delta/epsilon subdivisions,2YSJA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_990799_1	1165841.SULAR_03732	1.59e-104	315.0	COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,42M0J@68525|delta/epsilon subdivisions,2YNAU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iIT341.HP1101	G6PD_C,G6PD_N
k59_994263_3	1123517.JOMR01000001_gene489	1.1e-31	115.0	COG2363@1|root,COG2363@2|Bacteria,1MZX3@1224|Proteobacteria,1SCNB@1236|Gammaproteobacteria,461E1@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function (DUF423)	-	-	-	-	-	-	-	-	-	-	-	-	DUF423
k59_224961_1	1249480.B649_04430	1.15e-44	155.0	COG0726@1|root,COG0726@2|Bacteria,1PJQG@1224|Proteobacteria,42W09@68525|delta/epsilon subdivisions	1224|Proteobacteria	G	PFAM Polysaccharide deacetylase	nodB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.5.1.104	ko:K14659,ko:K22278	-	M00664	-	-	ko00000,ko00002,ko01000	-	-	-	Polysacc_deac_1
k59_1056469_1	1049564.TevJSym_av00430	1.87e-54	184.0	COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,1RN1Y@1236|Gammaproteobacteria,1J4CI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	hemN	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.98.3	ko:K02495	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R06895	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	iECIAI39_1322.ECIAI39_3134,iZ_1308.Z5403	HemN_C,Radical_SAM
k59_814691_1	1249480.B649_00655	5.52e-54	188.0	COG2604@1|root,COG2604@2|Bacteria,1R4P0@1224|Proteobacteria,42NB8@68525|delta/epsilon subdivisions,2YMMI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	hmm pf01973	pseE	-	-	-	-	-	-	-	-	-	-	-	MAF_flag10
k59_1464153_1	1304883.KI912532_gene3196	1.28e-77	234.0	COG1187@1|root,COG1187@2|Bacteria,1R9VV@1224|Proteobacteria,2VQAQ@28216|Betaproteobacteria,2KW2Q@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.20	ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
k59_1221772_1	709032.Sulku_1310	5.75e-95	292.0	COG1956@1|root,COG3604@1|root,COG1956@2|Bacteria,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,42Y69@68525|delta/epsilon subdivisions,2YNEN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	Transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF_2,HTH_8,Sigma54_activat
k59_1221772_2	326298.Suden_1336	4.03e-16	79.7	COG2199@1|root,COG3706@2|Bacteria,1NC00@1224|Proteobacteria,42NPP@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	diguanylate cyclase	-	-	2.7.7.65	ko:K13590,ko:K21088	ko02026,ko04112,map02026,map04112	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF,PAS_4
k59_931384_1	1249480.B649_09790	3.75e-88	267.0	COG0642@1|root,COG0642@2|Bacteria,1QZ1Z@1224|Proteobacteria,42SN7@68525|delta/epsilon subdivisions,2YPK7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
k59_541091_1	709032.Sulku_0217	6.19e-154	451.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,42SPZ@68525|delta/epsilon subdivisions,2YMS1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	fdhF	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_11538_1	1249480.B649_00095	6.58e-108	315.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42PA1@68525|delta/epsilon subdivisions,2YNMR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_11538_2	1249480.B649_00100	1.5e-53	173.0	COG0704@1|root,COG0704@2|Bacteria,1Q5TJ@1224|Proteobacteria,42STN@68525|delta/epsilon subdivisions,2YPRM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	PhoU family	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
k59_1712956_1	709032.Sulku_0803	1.02e-10	61.6	COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,4302Q@68525|delta/epsilon subdivisions,2YRWT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
k59_1712956_2	709032.Sulku_0796	3.02e-39	137.0	COG2863@1|root,COG2863@2|Bacteria,1NBPD@1224|Proteobacteria,42VXS@68525|delta/epsilon subdivisions,2YQ9N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
k59_361948_1	159087.Daro_1398	2.32e-34	127.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,2VIRD@28216|Betaproteobacteria,2KVEU@206389|Rhodocyclales	206389|Rhodocyclales	E	HMGL-like	-	-	2.3.3.14	ko:K02594	ko00620,map00620	-	R00271	RC00004,RC00067,RC02754	ko00000,ko00001,ko01000	-	-	-	HMGL-like
k59_361948_2	159087.Daro_1397	2.74e-63	199.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,2VMGF@28216|Betaproteobacteria,2KVBQ@206389|Rhodocyclales	206389|Rhodocyclales	E	Bacterial transferase hexapeptide (six repeats)	nifP	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
k59_11553_1	497321.C664_08778	2.58e-18	77.8	COG1396@1|root,COG1396@2|Bacteria,1PWHJ@1224|Proteobacteria,2VXU1@28216|Betaproteobacteria,2KZ8S@206389|Rhodocyclales	206389|Rhodocyclales	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_11553_2	497321.C664_08798	8.52e-23	92.8	28VQ6@1|root,2ZHS5@2|Bacteria,1P4DH@1224|Proteobacteria,2W5JH@28216|Betaproteobacteria,2KZEF@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_185683_2	583345.Mmol_2315	6.83e-06	55.5	COG1538@1|root,COG1538@2|Bacteria,1R6S1@1224|Proteobacteria,2VMHP@28216|Betaproteobacteria,2KP5M@206350|Nitrosomonadales	206350|Nitrosomonadales	MU	Outer membrane efflux protein	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
k59_1301394_1	709032.Sulku_1872	7.68e-78	239.0	COG1686@1|root,COG1686@2|Bacteria,1MWZA@1224|Proteobacteria,43AWC@68525|delta/epsilon subdivisions,2YT3V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
k59_361978_1	159087.Daro_3796	1.1e-59	193.0	2DB9W@1|root,2Z7Z9@2|Bacteria,1MZFV@1224|Proteobacteria,2VHWP@28216|Betaproteobacteria,2KVEW@206389|Rhodocyclales	206389|Rhodocyclales	C	Methane/Phenol/Toluene Hydroxylase	-	-	-	ko:K16243	ko00361,ko00362,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00623,map01100,map01120,map01220	M00548	R03560,R03608,R10042,R10043	RC00046,RC00490	ko00000,ko00001,ko00002	-	-	-	Phenol_Hydrox
k59_361978_2	292.DM42_5001	3.53e-37	127.0	2CJVU@1|root,32S7J@2|Bacteria,1N03Q@1224|Proteobacteria,2VUNQ@28216|Betaproteobacteria,1K9D4@119060|Burkholderiaceae	28216|Betaproteobacteria	C	MmoB/DmpM family	-	-	-	ko:K16244	ko00361,ko00362,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00623,map01100,map01120,map01220	M00548	R03560,R03608,R10042,R10043	RC00046,RC00490	ko00000,ko00001,ko00002	-	-	-	MmoB_DmpM
k59_658352_1	118797.XP_007457193.1	1.18e-24	100.0	COG0197@1|root,KOG3422@2759|Eukaryota,39S31@33154|Opisthokonta,3BPN3@33208|Metazoa,3DD65@33213|Bilateria	33208|Metazoa	J	Ribosomal protein S3, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	KH_2,Ribosomal_S3_C
k59_658352_2	1280952.HJA_11495	2.14e-10	57.8	COG0255@1|root,COG0255@2|Bacteria,1N6PR@1224|Proteobacteria,2UF59@28211|Alphaproteobacteria,43YI6@69657|Hyphomonadaceae	28211|Alphaproteobacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
k59_658352_3	717772.THIAE_00805	2.14e-70	218.0	COG0093@1|root,COG0093@2|Bacteria,1RCWZ@1224|Proteobacteria,1S3Z3@1236|Gammaproteobacteria,460HS@72273|Thiotrichales	72273|Thiotrichales	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
k59_1654513_1	709032.Sulku_1756	7.93e-46	164.0	COG2307@1|root,COG2308@1|root,COG2307@2|Bacteria,COG2308@2|Bacteria,1MX5P@1224|Proteobacteria,42NB9@68525|delta/epsilon subdivisions,2YNN4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E,CP_ATPgrasp_2
k59_1654513_2	1249480.B649_09270	1.65e-27	110.0	COG1305@1|root,COG4196@1|root,COG1305@2|Bacteria,COG4196@2|Bacteria,1MVAG@1224|Proteobacteria,42P26@68525|delta/epsilon subdivisions,2YN89@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Putative amidoligase enzyme (DUF2126)	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,DUF2126,Transglut_core
k59_1360149_1	62928.azo2282	7.57e-63	216.0	COG0835@1|root,COG0835@2|Bacteria,1QVCF@1224|Proteobacteria,2VK5W@28216|Betaproteobacteria,2KVUN@206389|Rhodocyclales	206389|Rhodocyclales	NT	Two component signalling adaptor domain	-	-	-	-	-	-	-	-	-	-	-	-	CheW
k59_1184753_1	709032.Sulku_1357	2.83e-143	425.0	COG0204@1|root,COG0477@1|root,COG0204@2|Bacteria,COG2814@2|Bacteria,1MWDY@1224|Proteobacteria,43BJD@68525|delta/epsilon subdivisions,2YNEB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	2-acylglycerophosphoethanolamine acyltransferase	aas	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
k59_1184753_2	1537917.JU82_01245	1.94e-12	65.5	COG3076@1|root,COG3076@2|Bacteria,1N195@1224|Proteobacteria,430TX@68525|delta/epsilon subdivisions,2YS1B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Family of unknown function (DUF695)	-	-	-	-	-	-	-	-	-	-	-	-	DUF695,RraB
k59_1713013_1	1165841.SULAR_06733	5.53e-96	295.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2YMA3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_772683_1	1121015.N789_08910	6.18e-05	43.9	COG0639@1|root,COG0639@2|Bacteria,1MV10@1224|Proteobacteria,1RPUJ@1236|Gammaproteobacteria,1X3SY@135614|Xanthomonadales	135614|Xanthomonadales	T	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP	apaH	GO:0003674,GO:0003824,GO:0004721,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008138,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564	3.6.1.41	ko:K01525	ko00230,map00230	-	R00125	RC00002	ko00000,ko00001,ko01000	-	-	-	Metallophos
k59_772683_2	159087.Daro_3931	1.27e-105	321.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,2VHVY@28216|Betaproteobacteria,2KVCK@206389|Rhodocyclales	206389|Rhodocyclales	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
k59_598223_1	159450.NH14_29345	7.69e-29	112.0	COG0834@1|root,COG0834@2|Bacteria,1MV5D@1224|Proteobacteria,2VHFS@28216|Betaproteobacteria,1K5X5@119060|Burkholderiaceae	28216|Betaproteobacteria	ET	PFAM extracellular solute-binding protein, family 3	gltI	-	-	ko:K10001	ko02010,ko02020,map02010,map02020	M00230	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.19,3.A.1.3.4	-	-	SBP_bac_3
k59_712871_1	1005995.GTPT_0509	2.78e-18	81.3	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,1RN09@1236|Gammaproteobacteria,4BU1Q@82986|Tatumella	1236|Gammaproteobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_2813,iPC815.YPO0040,iSBO_1134.SBO_3729,iSFV_1184.SFV_3881,iSFxv_1172.SFxv_4016,iUTI89_1310.UTI89_C4193	Guanylate_kin
k59_712871_2	1168067.JAGP01000001_gene2068	4.49e-31	110.0	COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,1SCSR@1236|Gammaproteobacteria,4618M@72273|Thiotrichales	72273|Thiotrichales	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
k59_362008_1	1123511.KB905843_gene1038	1.06e-71	234.0	COG2060@1|root,COG2060@2|Bacteria,1TPDF@1239|Firmicutes,4H2ZD@909932|Negativicutes	909932|Negativicutes	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane	kdpA	-	3.6.3.12	ko:K01546	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpA
k59_1654542_1	159087.Daro_1744	8.02e-47	155.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,2VH8A@28216|Betaproteobacteria,2KVY1@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
k59_1654542_2	1304883.KI912532_gene2605	5.01e-105	306.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,2VIUA@28216|Betaproteobacteria,2KV5P@206389|Rhodocyclales	206389|Rhodocyclales	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
k59_833487_1	1249480.B649_11805	7.32e-101	294.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,42QPX@68525|delta/epsilon subdivisions,2YNW3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
k59_11610_2	889378.Spiaf_0746	4.23e-22	98.2	COG0208@1|root,COG0208@2|Bacteria	2|Bacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdB	-	1.17.4.1	ko:K00526,ko:K03676	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03110,ko03400	-	-	-	ATP-cone,Ribonuc_red_sm
k59_891396_1	1528106.JRJE01000024_gene120	1.3e-07	60.8	COG1216@1|root,COG4261@1|root,COG1216@2|Bacteria,COG4261@2|Bacteria,1MVXJ@1224|Proteobacteria,2U2W1@28211|Alphaproteobacteria,2JQ7Y@204441|Rhodospirillales	204441|Rhodospirillales	M	Bacterial lipid A biosynthesis acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Lip_A_acyltrans
k59_11611_1	159087.Daro_4110	3.17e-49	162.0	COG0711@1|root,COG0711@2|Bacteria,1RHZ0@1224|Proteobacteria,2VRMS@28216|Betaproteobacteria,2KWEK@206389|Rhodocyclales	206389|Rhodocyclales	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
k59_1360191_1	1504672.669787028	2.52e-12	65.9	COG0492@1|root,COG0492@2|Bacteria,1MW14@1224|Proteobacteria,2VGZS@28216|Betaproteobacteria,4AB1B@80864|Comamonadaceae	28216|Betaproteobacteria	C	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	trxB2	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_3
k59_1360191_2	614083.AWQR01000037_gene3463	3.69e-73	219.0	COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,2VSJ0@28216|Betaproteobacteria,4AEDX@80864|Comamonadaceae	28216|Betaproteobacteria	C	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions	fdxA	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	DUF3470,Fer4,Fer4_10,Fer4_4
k59_1420747_1	90813.JQMT01000001_gene618	1.98e-75	252.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,1RMQE@1236|Gammaproteobacteria,45ZQ7@72273|Thiotrichales	72273|Thiotrichales	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HTH_12,OB_RNB,RNB,S1
k59_185760_1	748247.AZKH_3584	8.21e-18	83.6	COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,2VHYV@28216|Betaproteobacteria,2KVRC@206389|Rhodocyclales	206389|Rhodocyclales	H	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysC	-	2.7.1.25,2.7.7.4	ko:K00955	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU
k59_185760_2	709032.Sulku_1062	1.18e-35	125.0	COG1959@1|root,COG1959@2|Bacteria,1N7JE@1224|Proteobacteria,42UAE@68525|delta/epsilon subdivisions,2YPWZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
k59_658429_1	1537917.JU82_00925	4.11e-09	57.8	28NUA@1|root,2ZBSQ@2|Bacteria,1QE31@1224|Proteobacteria,42Z7U@68525|delta/epsilon subdivisions,2YR9R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_658429_2	1537917.JU82_00930	1.68e-82	248.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,42M3X@68525|delta/epsilon subdivisions,2YMCQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
k59_1067718_1	1249480.B649_05935	8.85e-66	205.0	2A2WP@1|root,30RAU@2|Bacteria,1PMAH@1224|Proteobacteria,42Y3T@68525|delta/epsilon subdivisions,2YQRJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	LptC
k59_1010304_1	1123518.ARWI01000001_gene1033	3.52e-56	176.0	COG0091@1|root,COG0091@2|Bacteria,1RH0W@1224|Proteobacteria,1S5XT@1236|Gammaproteobacteria,460UB@72273|Thiotrichales	72273|Thiotrichales	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
k59_712922_1	159087.Daro_3853	3.79e-166	472.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,2VHBB@28216|Betaproteobacteria,2KUR1@206389|Rhodocyclales	206389|Rhodocyclales	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
k59_712922_2	159087.Daro_3855	4.8e-25	96.3	COG3753@1|root,COG3753@2|Bacteria,1N7FF@1224|Proteobacteria,2VVTK@28216|Betaproteobacteria,2KZ92@206389|Rhodocyclales	206389|Rhodocyclales	S	Bacterial protein of unknown function (DUF937)	-	-	-	-	-	-	-	-	-	-	-	-	DUF937
k59_362093_1	159087.Daro_1100	3.82e-111	323.0	COG1309@1|root,COG1309@2|Bacteria,1RA4T@1224|Proteobacteria,2VQJU@28216|Betaproteobacteria,2KW6B@206389|Rhodocyclales	206389|Rhodocyclales	K	Bacterial transcriptional repressor C-terminal	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_13,TetR_N
k59_1713130_1	709032.Sulku_1071	8.66e-92	283.0	COG0702@1|root,COG0702@2|Bacteria,1PDTN@1224|Proteobacteria,42M8X@68525|delta/epsilon subdivisions,2YM7Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
k59_1771842_1	1249480.B649_01135	3.16e-47	163.0	COG0840@1|root,COG0840@2|Bacteria,1R5W9@1224|Proteobacteria,42SRV@68525|delta/epsilon subdivisions,2YR7J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	CZB,MCPsignal
k59_1538820_2	1537917.JU82_06940	5.55e-23	93.2	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,42QRC@68525|delta/epsilon subdivisions,2YNZB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
k59_362100_1	709032.Sulku_0240	2.5e-62	212.0	COG0745@1|root,COG0745@2|Bacteria,1QXJT@1224|Proteobacteria,42V47@68525|delta/epsilon subdivisions,2YQ8S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	RESPONSE REGULATOR receiver	-	-	-	ko:K07288	-	-	-	-	ko00000	-	-	-	-
k59_245777_1	709032.Sulku_1461	1.81e-130	379.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,42M5K@68525|delta/epsilon subdivisions,2YMJ2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
k59_1713144_2	709032.Sulku_0304	9.21e-31	114.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,42RV8@68525|delta/epsilon subdivisions,2YPC0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
k59_11693_1	159087.Daro_4111	2.39e-12	63.9	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,2VSJV@28216|Betaproteobacteria,2KWKN@206389|Rhodocyclales	206389|Rhodocyclales	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
k59_421436_1	159087.Daro_3252	6.72e-31	114.0	COG3161@1|root,COG3161@2|Bacteria,1N8BF@1224|Proteobacteria,2VU5V@28216|Betaproteobacteria,2KXAX@206389|Rhodocyclales	206389|Rhodocyclales	H	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway	ubiC	-	4.1.3.40	ko:K03181	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R01302	RC00491,RC02148	ko00000,ko00001,ko00002,ko01000	-	-	-	Chor_lyase
k59_421436_2	159087.Daro_3253	2.41e-77	232.0	COG1430@1|root,COG1430@2|Bacteria,1MZBJ@1224|Proteobacteria,2VSCK@28216|Betaproteobacteria,2KWQ3@206389|Rhodocyclales	206389|Rhodocyclales	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
k59_951368_1	709032.Sulku_2343	9.7e-75	227.0	COG5456@1|root,COG5456@2|Bacteria	2|Bacteria	P	FixH	-	-	-	-	-	-	-	-	-	-	-	-	FixH,YtkA
k59_951368_2	1249480.B649_11090	2.97e-20	90.1	COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,1QUIU@1224|Proteobacteria,42M7I@68525|delta/epsilon subdivisions,2YMX0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG3893 inactivated superfamily I helicase	addB	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
k59_1538846_1	398578.Daci_4922	7.96e-10	58.9	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,4A9PA@80864|Comamonadaceae	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GAF_2,GGDEF,PAS_4,PAS_8,PAS_9
k59_1713164_1	159087.Daro_2448	5.06e-75	243.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,2VI1P@28216|Betaproteobacteria,2KUVE@206389|Rhodocyclales	206389|Rhodocyclales	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
k59_1713164_2	159087.Daro_2449	2.5e-46	150.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,2VU1D@28216|Betaproteobacteria,2KX1E@206389|Rhodocyclales	206389|Rhodocyclales	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
k59_1420881_1	159087.Daro_3986	1.73e-90	268.0	COG0680@1|root,COG0680@2|Bacteria,1RE1C@1224|Proteobacteria,2VJ4W@28216|Betaproteobacteria,2KWD1@206389|Rhodocyclales	206389|Rhodocyclales	C	Hydrogenase maturation protease	-	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
k59_1420881_2	1485545.JQLW01000005_gene930	5.85e-19	83.2	COG1969@1|root,COG1969@2|Bacteria,1MU87@1224|Proteobacteria	1224|Proteobacteria	C	Ni Fe-hydrogenase, b-type cytochrome subunit	hyaC	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
k59_1713166_1	709032.Sulku_0034	5.71e-32	130.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,43BRF@68525|delta/epsilon subdivisions,2YNRK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	TonB-dependent receptor plug	-	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
k59_1360321_1	1537917.JU82_07385	5.78e-107	322.0	COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,42MQ6@68525|delta/epsilon subdivisions,2YNPN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DNA photolyase family	phrB	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
k59_1716568_1	1454004.AW11_00641	1.57e-77	253.0	COG2204@1|root,COG5001@1|root,COG2204@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_4,PAS_9,Response_reg
k59_662922_1	709032.Sulku_2030	7.03e-93	285.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,42NYV@68525|delta/epsilon subdivisions,2YN1D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	pyridine nucleotide-disulfide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_955124_1	90813.JQMT01000001_gene819	1.1e-117	347.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,1RNCP@1236|Gammaproteobacteria,45ZV4@72273|Thiotrichales	72273|Thiotrichales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
k59_1716574_1	1163617.SCD_n00974	6.51e-81	262.0	COG1729@1|root,COG1729@2|Bacteria,1MZ7N@1224|Proteobacteria,2VNYC@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_955129_1	709032.Sulku_1424	1.06e-45	162.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,42M1S@68525|delta/epsilon subdivisions,2YMEF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	penicillin-binding protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
k59_955129_2	1249480.B649_05915	6.33e-62	194.0	2AJ0Z@1|root,319J3@2|Bacteria,1Q2X3@1224|Proteobacteria,42WDT@68525|delta/epsilon subdivisions,2YQI2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_955129_3	1537917.JU82_09260	1.72e-38	128.0	COG1246@1|root,COG1246@2|Bacteria	2|Bacteria	E	Belongs to the acetyltransferase family. ArgA subfamily	argH	GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,4.3.2.1	ko:K00619,ko:K14681	ko00220,ko00250,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map01100,map01110,map01130,map01210,map01230	M00028,M00029,M00844	R00259,R01086	RC00004,RC00064,RC00445,RC00447	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0946	ASL_C2,Acetyltransf_1,Lyase_1
k59_662938_1	944547.ABLL_2657	1.84e-16	75.1	COG0607@1|root,COG0607@2|Bacteria,1PEYP@1224|Proteobacteria,42WCJ@68525|delta/epsilon subdivisions,2YQA7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_662938_2	709032.Sulku_1191	4.27e-45	152.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,42NY7@68525|delta/epsilon subdivisions,2YNB3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	exodeoxyribonuclease III	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
k59_1482729_1	1249480.B649_08975	1.01e-33	129.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,42MG3@68525|delta/epsilon subdivisions,2YMCB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	ABC-type transport system involved in resistance to organic solvents permease component	iamB	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE,STAS,STAS_2
k59_306278_1	1453503.AU05_16990	3.85e-42	153.0	COG4618@1|root,COG4618@2|Bacteria,1NTI5@1224|Proteobacteria,1T1HR@1236|Gammaproteobacteria,1YCYE@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06148,ko:K12536	ko02010,map02010	M00328	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1,3.A.1.110	-	-	ABC_membrane,ABC_tran
k59_1188109_2	1537917.JU82_07565	6.9e-40	140.0	COG1723@1|root,COG1723@2|Bacteria,1MWYM@1224|Proteobacteria,42URC@68525|delta/epsilon subdivisions,2YPX0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Uncharacterised ACR, YagE family COG1723	-	-	-	-	-	-	-	-	-	-	-	-	DUF155
k59_1071674_2	1249480.B649_00375	2.53e-49	164.0	2A50M@1|root,30TNT@2|Bacteria,1PDM4@1224|Proteobacteria,42QJ6@68525|delta/epsilon subdivisions,2YPYD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	AMIN domain	-	-	-	-	-	-	-	-	-	-	-	-	AMIN
k59_545802_1	1249480.B649_07265	1.87e-39	139.0	COG0688@1|root,COG0688@2|Bacteria,1MVT4@1224|Proteobacteria,42PAW@68525|delta/epsilon subdivisions,2YNM3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
k59_545802_2	709032.Sulku_1572	1.77e-93	282.0	COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,42P4E@68525|delta/epsilon subdivisions,2YNAC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs	truD	-	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
k59_1716601_1	1537917.JU82_07090	8.04e-86	258.0	COG0688@1|root,COG0688@2|Bacteria,1P7K4@1224|Proteobacteria,42TG5@68525|delta/epsilon subdivisions,2YQHE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	phosphatidylserine decarboxylase	-	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
k59_1716602_1	580332.Slit_0673	3.66e-104	316.0	COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,2VHZX@28216|Betaproteobacteria,44V1S@713636|Nitrosomonadales	28216|Betaproteobacteria	J	PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic domain	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
k59_1624794_2	1537917.JU82_06500	2.64e-69	222.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,42MJ7@68525|delta/epsilon subdivisions,2YMWU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	COG0402 Cytosine deaminase and related metal-dependent	orf1	-	3.5.4.40	ko:K20810	ko00130,ko01110,map00130,map01110	-	R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k59_1213535_1	1150621.SMUL_0887	2.82e-27	109.0	COG0008@1|root,COG0064@1|root,COG0008@2|Bacteria,COG0064@2|Bacteria,1MUC8@1224|Proteobacteria,42MAX@68525|delta/epsilon subdivisions,2YNBY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	PFAM tRNA synthetases class I (E and Q), catalytic domain	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	GatB_Yqey,tRNA-synt_1c,tRNA-synt_1c_C
k59_1213535_2	1165841.SULAR_04257	2.63e-89	275.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,42NHA@68525|delta/epsilon subdivisions,2YMYU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX1	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
k59_92727_1	765914.ThisiDRAFT_0378	2.29e-19	92.8	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,1RS25@1236|Gammaproteobacteria,1WXAZ@135613|Chromatiales	135613|Chromatiales	T	EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
k59_1624855_1	1537917.JU82_07105	1.84e-187	527.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,42M7H@68525|delta/epsilon subdivisions,2YMPK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
k59_1328530_2	1249480.B649_09170	4.69e-24	97.8	COG0647@1|root,COG0647@2|Bacteria,1PYVR@1224|Proteobacteria,42NA1@68525|delta/epsilon subdivisions,2YMK0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	HAD-superfamily hydrolase, subfamily IIA	-	-	-	ko:K02566	-	-	-	-	ko00000	-	-	-	Hydrolase_6,Hydrolase_like
k59_1624868_2	227377.CBU_0242	1.96e-47	153.0	COG0185@1|root,COG0185@2|Bacteria,1RGYX@1224|Proteobacteria,1S5VT@1236|Gammaproteobacteria,1JEQJ@118969|Legionellales	118969|Legionellales	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
k59_1682755_1	929558.SMGD1_1018	2.26e-58	198.0	COG2208@1|root,COG4753@1|root,COG2208@2|Bacteria,COG4753@2|Bacteria,1QYCW@1224|Proteobacteria,43CBA@68525|delta/epsilon subdivisions,2YTB1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	Stage II sporulation protein E (SpoIIE)	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,SpoIIE
k59_160646_2	1537917.JU82_10765	3.17e-68	213.0	COG1684@1|root,COG1684@2|Bacteria,1NIF4@1224|Proteobacteria,42NX7@68525|delta/epsilon subdivisions,2YMKE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Flagellar biosynthetic protein fliR	fliR	-	-	ko:K02421	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1
k59_1799089_1	1537917.JU82_02045	2.31e-32	121.0	COG0845@1|root,COG0845@2|Bacteria,1QMYR@1224|Proteobacteria,42WWX@68525|delta/epsilon subdivisions,2YR01@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	RND family efflux transporter, MFP subunit	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
k59_1799089_2	709032.Sulku_2260	4.23e-113	352.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42M0A@68525|delta/epsilon subdivisions,2YNJ1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	cznA	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
k59_92767_1	159087.Daro_2901	2.9e-34	120.0	COG2198@1|root,COG2198@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
k59_92767_2	1304883.KI912532_gene2020	3.3e-43	149.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,2VH1F@28216|Betaproteobacteria,2KUVS@206389|Rhodocyclales	206389|Rhodocyclales	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,Response_reg
k59_1682766_1	1165841.SULAR_07825	7.15e-46	152.0	COG0811@1|root,COG0811@2|Bacteria,1MX5J@1224|Proteobacteria,42NWR@68525|delta/epsilon subdivisions,2YPQJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	MotA TolQ ExbB proton channel	-	-	-	-	-	-	-	-	-	-	-	-	MotA_ExbB
k59_1682766_2	1165841.SULAR_07830	1.14e-67	217.0	COG0811@1|root,COG0811@2|Bacteria,1MX5J@1224|Proteobacteria,42NWR@68525|delta/epsilon subdivisions,2YPQJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k59_449705_1	709032.Sulku_1366	1.36e-86	275.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,42M6A@68525|delta/epsilon subdivisions,2YMN6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA_synt_2f
k59_693696_1	1249480.B649_01400	1.95e-107	326.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,42NF8@68525|delta/epsilon subdivisions,2YMBT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	ATP-dependent DNA helicase	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
k59_1097482_1	395494.Galf_1742	1.15e-72	238.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VH8J@28216|Betaproteobacteria,44VM9@713636|Nitrosomonadales	28216|Betaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copA	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
k59_1328584_1	1537917.JU82_11020	1.72e-72	231.0	COG3203@1|root,COG3203@2|Bacteria	2|Bacteria	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	oprD	-	-	ko:K08720,ko:K18093	ko01501,ko02020,ko05111,map01501,map02020,map05111	M00745	-	-	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	1.B.1.2.1,1.B.25.1.1	-	iJN746.PP_1206	Alginate_exp,BBP2,OprD,Porin_4
k59_1682785_1	1169143.KB911041_gene486	4.04e-09	62.0	COG0500@1|root,COG2226@2|Bacteria,1QTWC@1224|Proteobacteria,2VQ89@28216|Betaproteobacteria,1K213@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k59_1682785_2	243365.CV_1254	3.62e-39	141.0	COG0491@1|root,COG0491@2|Bacteria,1MU8Q@1224|Proteobacteria,2VGZG@28216|Betaproteobacteria,2KQZD@206351|Neisseriales	206351|Neisseriales	S	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	gloB	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	HAGH_C,Lactamase_B
k59_805979_1	709032.Sulku_1640	2.19e-19	84.3	COG3221@1|root,COG3221@2|Bacteria,1R4SK@1224|Proteobacteria,42V0V@68525|delta/epsilon subdivisions,2YS63@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
k59_805979_2	1537917.JU82_04280	5.37e-21	91.3	2AN97@1|root,32J0R@2|Bacteria,1PCA3@1224|Proteobacteria,42T7U@68525|delta/epsilon subdivisions,2YPPF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Flg_hook
k59_1213654_1	1249480.B649_06365	2.01e-66	226.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YNS1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4
k59_1097523_1	159087.Daro_2030	1.97e-137	394.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,2VHYP@28216|Betaproteobacteria,2KVT3@206389|Rhodocyclales	206389|Rhodocyclales	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
k59_1624988_1	709032.Sulku_0416	3.56e-21	87.8	COG1357@1|root,COG1357@2|Bacteria,1N7U9@1224|Proteobacteria,42X3G@68525|delta/epsilon subdivisions,2YQWW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Pentapeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
k59_1624988_2	709032.Sulku_0423	2.03e-62	200.0	COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,42NWB@68525|delta/epsilon subdivisions,2YP3D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
k59_1455611_1	1537917.JU82_00945	2.82e-109	325.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,42N2A@68525|delta/epsilon subdivisions,2YMD3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
k59_1160593_1	159087.Daro_0265	5.93e-19	87.4	COG0642@1|root,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,2VIXT@28216|Betaproteobacteria,2KUH6@206389|Rhodocyclales	206389|Rhodocyclales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2222,HAMP,HATPase_c,HisKA,Response_reg,dCache_1
k59_1160593_2	159087.Daro_0264	7.63e-54	174.0	COG2197@1|root,COG2197@2|Bacteria,1P4TD@1224|Proteobacteria,2VMX4@28216|Betaproteobacteria,2KW82@206389|Rhodocyclales	206389|Rhodocyclales	K	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_217224_1	159087.Daro_1398	2.45e-52	175.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,2VIRD@28216|Betaproteobacteria,2KVEU@206389|Rhodocyclales	206389|Rhodocyclales	E	HMGL-like	-	-	2.3.3.14	ko:K02594	ko00620,map00620	-	R00271	RC00004,RC00067,RC02754	ko00000,ko00001,ko01000	-	-	-	HMGL-like
k59_217224_2	159087.Daro_0514	5.72e-29	109.0	COG2265@1|root,COG2265@2|Bacteria,1QV4X@1224|Proteobacteria,2WGYG@28216|Betaproteobacteria,2KX4K@206389|Rhodocyclales	206389|Rhodocyclales	J	Thiopurine S-methyltransferase (TPMT)	-	-	2.1.1.67	ko:K00569	ko00983,map00983	-	R08236,R08239,R08246	RC00003,RC00980,RC02277	ko00000,ko00001,ko01000	-	-	-	TPMT
k59_1160602_2	1304883.KI912532_gene2355	2.03e-116	350.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,2VHEB@28216|Betaproteobacteria,2KWDX@206389|Rhodocyclales	206389|Rhodocyclales	E	COG0010 Arginase agmatinase formimionoglutamate hydrolase, arginase family	rocD	-	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3,Arginase
k59_1682858_1	1537917.JU82_03760	2.24e-52	181.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,42NF8@68525|delta/epsilon subdivisions,2YMBT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	ATP-dependent DNA helicase	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
k59_1682858_2	709032.Sulku_0316	6.08e-74	234.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,42M74@68525|delta/epsilon subdivisions,2YMI1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Peptidase, M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_859733_1	929558.SMGD1_1738	8.15e-103	305.0	2DUCA@1|root,32UX0@2|Bacteria,1P3VR@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1328695_1	709032.Sulku_1432	3.46e-65	206.0	COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,42PQF@68525|delta/epsilon subdivisions,2YMTU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
k59_1328695_2	1249480.B649_05955	1.76e-45	159.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,42M5C@68525|delta/epsilon subdivisions,2YM7M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	lytic murein transglycosylase	mltD	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
k59_631088_1	1123393.KB891316_gene2055	1.73e-102	320.0	COG4258@1|root,COG4258@2|Bacteria,1MU1E@1224|Proteobacteria,2VHXY@28216|Betaproteobacteria,1KSXD@119069|Hydrogenophilales	119069|Hydrogenophilales	S	MMPL family	-	-	-	-	-	-	-	-	-	-	-	-	MMPL
k59_1047602_1	1249480.B649_03190	3.74e-129	376.0	COG1143@1|root,COG2768@1|root,COG1143@2|Bacteria,COG2768@2|Bacteria,1N7HT@1224|Proteobacteria	1224|Proteobacteria	C	4fe-4s ferredoxin, iron-sulfur binding	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
k59_1047602_2	709032.Sulku_0645	8.85e-41	139.0	COG0169@1|root,COG0169@2|Bacteria,1Q1X7@1224|Proteobacteria,431CA@68525|delta/epsilon subdivisions,2YSA4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	-	-	-	-	-	-	-	-	-	-	-	-	Shikimate_dh_N
k59_327052_2	387093.SUN_1515	6.11e-30	119.0	COG1216@1|root,COG1216@2|Bacteria,1N5RX@1224|Proteobacteria,42SF0@68525|delta/epsilon subdivisions,2YRNI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
k59_160769_1	1537917.JU82_11750	1.42e-88	265.0	COG0806@1|root,COG0806@2|Bacteria,1MYUH@1224|Proteobacteria,42SEN@68525|delta/epsilon subdivisions,2YPH6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
k59_693843_2	378806.STAUR_7615	3.58e-16	80.9	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2YZB5@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II/IV secretion system protein	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
k59_388184_1	1249480.B649_01710	1.96e-51	166.0	COG1040@1|root,COG1040@2|Bacteria,1Q1C2@1224|Proteobacteria,42T93@68525|delta/epsilon subdivisions,2YPEB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	transformation system protein	ctsW	-	-	ko:K02242	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	Pribosyltran
k59_388184_2	709032.Sulku_0375	8.26e-114	342.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,42M3D@68525|delta/epsilon subdivisions,2YMAA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
k59_693851_1	1500301.JQMF01000006_gene1773	5.42e-41	155.0	COG5108@1|root,COG5108@2|Bacteria,1PIWB@1224|Proteobacteria,2U1JR@28211|Alphaproteobacteria,4BC0X@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	DNA-directed RNA polymerase N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	RNA_pol,RPOL_N
k59_1743390_1	159087.Daro_3354	2.52e-95	298.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1MUQV@1224|Proteobacteria,2VJ24@28216|Betaproteobacteria,2KZNZ@206389|Rhodocyclales	206389|Rhodocyclales	T	LapD/MoxY periplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,LapD_MoxY_N
k59_327103_1	387093.SUN_0313	1.05e-32	117.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,42RHG@68525|delta/epsilon subdivisions,2YNVV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	bacterioferritin comigratory protein	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
k59_1047651_1	1537917.JU82_07270	5.1e-172	486.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,42NF2@68525|delta/epsilon subdivisions,2YMGD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
k59_1573492_1	1249480.B649_02860	1.06e-40	135.0	292GE@1|root,2ZQ0K@2|Bacteria,1Q2XF@1224|Proteobacteria,42WEN@68525|delta/epsilon subdivisions,2YQBC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_272847_2	709032.Sulku_2099	3.05e-64	212.0	COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,42MCZ@68525|delta/epsilon subdivisions,2YMYT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	type I secretion membrane fusion protein, HlyD family	-	-	-	ko:K12542,ko:K16300	-	M00330,M00571	-	-	ko00000,ko00002,ko02000,ko02044	3.A.1.109.4,8.A.1,8.A.1.3.3	-	-	Biotin_lipoyl_2,HlyD,HlyD_3
k59_1160693_1	159087.Daro_0979	1.77e-121	364.0	COG1894@1|root,COG1905@1|root,COG1894@2|Bacteria,COG1905@2|Bacteria,1MV8F@1224|Proteobacteria,2VHW2@28216|Betaproteobacteria,2KUYG@206389|Rhodocyclales	206389|Rhodocyclales	C	Respiratory-chain NADH dehydrogenase	hoxF	-	1.12.1.2	ko:K18005	-	-	-	-	ko00000,ko01000	-	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
k59_631178_1	159087.Daro_0887	4.83e-24	94.7	COG3156@1|root,COG3156@2|Bacteria,1QWG1@1224|Proteobacteria,2WGYJ@28216|Betaproteobacteria,2KXFM@206389|Rhodocyclales	206389|Rhodocyclales	U	type II secretion system protein K	-	-	-	ko:K12286	-	-	-	-	ko00000,ko02044	-	-	-	-
k59_631178_2	583345.Mmol_1201	1.9e-23	99.8	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	DUF4214,DUF4347,LRR_5,PD40,Pkinase
k59_513367_1	709032.Sulku_0343	2.82e-65	213.0	COG1413@1|root,COG1413@2|Bacteria,1Q1TE@1224|Proteobacteria,42UC8@68525|delta/epsilon subdivisions,2YPXK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1799332_2	1537917.JU82_10390	2.64e-83	252.0	28I9W@1|root,2Z8CH@2|Bacteria,1QCN6@1224|Proteobacteria,42Z77@68525|delta/epsilon subdivisions,2YRAX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	SIR2-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
k59_988806_1	1449345.JHWC01000005_gene1177	2.16e-53	177.0	COG1817@1|root,COG1817@2|Bacteria,1N644@1224|Proteobacteria,42Q0A@68525|delta/epsilon subdivisions,2YMH5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF354)	-	-	-	ko:K09726	-	-	-	-	ko00000	-	-	-	DUF354
k59_988806_2	537972.ABQU01000064_gene1488	1.5e-10	62.8	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,42MEI@68525|delta/epsilon subdivisions,2YM9T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_452971_1	929558.SMGD1_0680	1.15e-12	72.8	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,43AX5@68525|delta/epsilon subdivisions,2YT40@29547|Epsilonproteobacteria	1224|Proteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_9,Response_reg
k59_1747509_1	709032.Sulku_0395	1.23e-117	350.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2YMB5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	abc transporter atp-binding protein	yheS	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
k59_163613_2	697282.Mettu_3408	1.95e-21	96.3	COG4191@1|root,COG4191@2|Bacteria,1MXRR@1224|Proteobacteria,1RQ1E@1236|Gammaproteobacteria,1XEHP@135618|Methylococcales	135618|Methylococcales	KT	PAS PAC sensor signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS
k59_516212_1	1249480.B649_11140	2.45e-05	44.7	COG2952@1|root,COG2952@2|Bacteria,1PBRU@1224|Proteobacteria,42MEP@68525|delta/epsilon subdivisions,2YN8A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09804	-	-	-	-	ko00000	-	-	-	DUF507
k59_697502_2	1537917.JU82_01610	3.06e-50	160.0	COG1677@1|root,COG1677@2|Bacteria,1NIFD@1224|Proteobacteria,42V59@68525|delta/epsilon subdivisions,2YQF1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Flagellar hook-basal body complex protein FliE	fliE	-	-	ko:K02408	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliE
k59_1459237_1	1537917.JU82_01220	2.04e-31	117.0	COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,42R55@68525|delta/epsilon subdivisions,2YNS0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
k59_453025_1	1502770.JQMG01000001_gene1984	4.37e-57	177.0	COG3450@1|root,COG3450@2|Bacteria,1N8CD@1224|Proteobacteria,2WG9Q@28216|Betaproteobacteria,2KN3D@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Protein of unknown function (DUF861)	-	-	-	ko:K06995	-	-	-	-	ko00000	-	-	-	Cupin_3
k59_1802821_1	1537917.JU82_10825	1.01e-82	248.0	29BMV@1|root,2ZYK6@2|Bacteria,1Q9EE@1224|Proteobacteria,42VEN@68525|delta/epsilon subdivisions,2YQKT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1802821_2	709032.Sulku_0252	1.93e-22	94.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,42MVI@68525|delta/epsilon subdivisions,2YMGY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	aldo keto reductase	tas	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_1686145_1	1000565.METUNv1_03167	1.77e-48	158.0	COG0745@1|root,COG0745@2|Bacteria,1RD7E@1224|Proteobacteria,2VVWD@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Pfam Response regulator receiver	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
k59_1163736_1	1537917.JU82_11150	1.55e-121	361.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,42M1C@68525|delta/epsilon subdivisions,2YMF3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
k59_163679_1	911008.GLAD_00008	9.74e-09	62.8	COG0840@1|root,COG0840@2|Bacteria	2|Bacteria	NT	transmembrane signaling receptor activity	-	-	-	ko:K02067,ko:K03406	ko02010,ko02020,ko02030,map02010,map02020,map02030	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000,ko02035	3.A.1.27	-	-	CZB,MCPsignal,MlaD,Peripla_BP_4,SBP_bac_5
k59_863277_1	1537917.JU82_01685	1.17e-108	316.0	COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,42MZP@68525|delta/epsilon subdivisions,2YMN7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
k59_163682_1	1269813.ATUL01000033_gene78	8.89e-38	138.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1S5IM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_453100_1	1165841.SULAR_02763	1.83e-82	244.0	COG2033@1|root,COG2033@2|Bacteria,1NDWH@1224|Proteobacteria,42RSM@68525|delta/epsilon subdivisions,2YP5S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Desulfoferrodoxin ferrous iron-binding	-	-	1.15.1.2	ko:K05919	-	-	-	-	ko00000,ko01000	-	-	-	Desulfoferrodox
k59_924696_1	159087.Daro_0951	6.54e-94	276.0	COG0852@1|root,COG0852@2|Bacteria,1MX4B@1224|Proteobacteria,2VHHV@28216|Betaproteobacteria,2KUVB@206389|Rhodocyclales	206389|Rhodocyclales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
k59_276363_1	136037.KDR07995	2.62e-19	90.5	COG0471@1|root,KOG1281@2759|Eukaryota,38C60@33154|Opisthokonta,3BBN0@33208|Metazoa,3CTA5@33213|Bilateria,41WJS@6656|Arthropoda,3SIE6@50557|Insecta	33208|Metazoa	P	transporter activity. It is involved in the biological process described with sodium ion transport	SLC13A5	GO:0003674,GO:0005215,GO:0005310,GO:0005342,GO:0005343,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0006820,GO:0006835,GO:0006842,GO:0006848,GO:0006855,GO:0007275,GO:0007568,GO:0008028,GO:0008150,GO:0008152,GO:0008324,GO:0008340,GO:0008509,GO:0008514,GO:0010259,GO:0010883,GO:0010889,GO:0015075,GO:0015077,GO:0015081,GO:0015137,GO:0015141,GO:0015142,GO:0015238,GO:0015291,GO:0015293,GO:0015294,GO:0015318,GO:0015361,GO:0015362,GO:0015370,GO:0015556,GO:0015672,GO:0015711,GO:0015718,GO:0015740,GO:0015744,GO:0015746,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0016323,GO:0017153,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0032501,GO:0032502,GO:0032879,GO:0034220,GO:0035674,GO:0035725,GO:0040008,GO:0040014,GO:0040018,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045927,GO:0046873,GO:0046942,GO:0046943,GO:0048518,GO:0048638,GO:0048639,GO:0048856,GO:0050789,GO:0050793,GO:0050833,GO:0050896,GO:0051094,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0055085,GO:0065007,GO:0065008,GO:0071422,GO:0071702,GO:0071704,GO:0071944,GO:0098590,GO:0098655,GO:0098656,GO:0098660,GO:0098662,GO:1901475,GO:1903825,GO:1905039,GO:1905952	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
k59_276363_2	709032.Sulku_0826	1.74e-47	153.0	COG4627@1|root,COG4627@2|Bacteria,1NHR6@1224|Proteobacteria,42VA4@68525|delta/epsilon subdivisions,2YQEV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Stress responsive A B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
k59_809405_1	1304883.KI912532_gene1758	3.14e-116	346.0	COG3434@1|root,COG3434@2|Bacteria,1RJMI@1224|Proteobacteria,2WFNM@28216|Betaproteobacteria,2KYSF@206389|Rhodocyclales	206389|Rhodocyclales	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_1869287_1	717773.Thicy_0051	6.49e-53	180.0	COG2010@1|root,COG2010@2|Bacteria,1QVK1@1224|Proteobacteria,1RYEK@1236|Gammaproteobacteria,4621F@72273|Thiotrichales	72273|Thiotrichales	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrome_CBB3
k59_1802934_1	929558.SMGD1_0802	1.72e-96	295.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,42M0I@68525|delta/epsilon subdivisions,2YMV0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
k59_184790_1	1536774.H70357_10265	1.13e-65	224.0	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,4HAHU@91061|Bacilli,26Q93@186822|Paenibacillaceae	91061|Bacilli	Q	Non-ribosomal peptide synthetase modules and related proteins	nrsB	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
k59_890424_2	1249480.B649_03450	1.08e-44	146.0	COG3951@1|root,COG3951@2|Bacteria,1Q5W9@1224|Proteobacteria,42UQG@68525|delta/epsilon subdivisions,2YPWJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MNO	Rod binding protein	flgJ	-	-	-	-	-	-	-	-	-	-	-	Rod-binding
k59_10816_1	1094980.Mpsy_2226	5.45e-10	59.7	COG4828@1|root,arCOG03300@2157|Archaea,2Y0K6@28890|Euryarchaeota,2NA5G@224756|Methanomicrobia	224756|Methanomicrobia	S	Protein of unknown function (DUF1622)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1622
k59_10816_2	395494.Galf_2529	5.27e-14	65.9	COG0425@1|root,COG0425@2|Bacteria,1MZA5@1224|Proteobacteria,2VVW5@28216|Betaproteobacteria,44WKX@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	TusA
k59_184798_2	1537917.JU82_02630	4.55e-35	124.0	COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,42SB8@68525|delta/epsilon subdivisions,2YPI9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA	gidB	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
k59_1537597_1	1249480.B649_00615	3.88e-60	197.0	COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1R8DG@1224|Proteobacteria,42NGC@68525|delta/epsilon subdivisions,2YN3X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the ompA family	cadF	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA
k59_890435_1	387093.SUN_0171	6.95e-69	221.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,42NR8@68525|delta/epsilon subdivisions,2YTM9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Peptidase dimerisation domain	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
k59_1183929_1	159087.Daro_2405	1.99e-39	143.0	COG0438@1|root,COG0438@2|Bacteria,1MVIM@1224|Proteobacteria,2VJT7@28216|Betaproteobacteria,2KUCI@206389|Rhodocyclales	206389|Rhodocyclales	M	Glycosyl transferases group 1	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_trans_1_4,Glyco_transf_4
k59_1183929_2	765910.MARPU_05435	3.5e-05	46.6	COG1269@1|root,COG1269@2|Bacteria,1MXZG@1224|Proteobacteria,1RQYZ@1236|Gammaproteobacteria,1WX9D@135613|Chromatiales	135613|Chromatiales	C	eight transmembrane protein EpsH	-	-	-	-	-	-	-	-	-	-	-	-	DUF3485,Exosortase_EpsH
k59_1594907_1	387093.SUN_0605	2.08e-80	252.0	COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,42P1M@68525|delta/epsilon subdivisions,2YN96@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Peptidase M48	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
k59_1066576_1	1537917.JU82_07765	4.41e-148	424.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,42NR0@68525|delta/epsilon subdivisions,2YMUN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
k59_1066576_2	1537917.JU82_07770	3.98e-115	341.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,42MMB@68525|delta/epsilon subdivisions,2YMVM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
k59_244712_1	1537917.JU82_02455	2.41e-118	361.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42P9M@68525|delta/epsilon subdivisions,2YNH7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CZB,HAMP,MCPsignal,dCache_3
k59_10833_1	1537917.JU82_05105	4.38e-88	286.0	COG3164@1|root,COG3164@2|Bacteria,1QUYX@1224|Proteobacteria,43CES@68525|delta/epsilon subdivisions,2YTC9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
k59_1126487_1	1249480.B649_00095	1.72e-11	62.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42PA1@68525|delta/epsilon subdivisions,2YNMR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_1126487_2	1537917.JU82_02980	1.01e-53	183.0	COG0642@1|root,COG2205@2|Bacteria,1QUJ7@1224|Proteobacteria,43BJF@68525|delta/epsilon subdivisions,2YNM7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,sCache_like
k59_480678_1	709032.Sulku_0566	1.65e-64	219.0	COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2YMB9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	chemotaxis protein	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k59_832509_1	1217658.F987_01614	1.39e-06	60.5	2DNY5@1|root,32ZRU@2|Bacteria,1R0G1@1224|Proteobacteria,1S2GW@1236|Gammaproteobacteria,3NNV1@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1126488_1	387093.SUN_1986	3.3e-72	234.0	COG0069@1|root,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2YNFI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	COGs COG0069 Glutamate synthase domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase
k59_1712180_1	1487953.JMKF01000071_gene3390	9.63e-28	120.0	COG4191@1|root,COG4191@2|Bacteria,1G4CY@1117|Cyanobacteria,1HA51@1150|Oscillatoriales	1117|Cyanobacteria	T	PAS PAC sensor signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_9
k59_1009136_1	159087.Daro_1797	1.54e-164	464.0	COG2518@1|root,COG2518@2|Bacteria,1NMMQ@1224|Proteobacteria,2VH3B@28216|Betaproteobacteria,2KVG3@206389|Rhodocyclales	206389|Rhodocyclales	O	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_32
k59_1009136_2	159087.Daro_1796	3.69e-43	154.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,2VHHU@28216|Betaproteobacteria,2KVK7@206389|Rhodocyclales	206389|Rhodocyclales	O	Peptidase U32	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
k59_597285_1	1502770.JQMG01000001_gene1974	5.63e-37	127.0	COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,2VR40@28216|Betaproteobacteria,2KMMX@206350|Nitrosomonadales	206350|Nitrosomonadales	J	binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
k59_597285_2	426114.THI_2447	1.79e-11	63.5	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,2VIKN@28216|Betaproteobacteria,1KJ8B@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
k59_420563_1	709032.Sulku_0432	1.95e-76	249.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2YMW4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_10892_1	387093.SUN_0355	5.2e-52	176.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,42M8P@68525|delta/epsilon subdivisions,2YN6C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	peptidase U32 family	prtC	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
k59_1537703_1	1165841.SULAR_06948	1.35e-120	362.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,42M35@68525|delta/epsilon subdivisions,2YM7I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0354	DXP_synthase_N,Transket_pyr,Transketolase_C
k59_184894_1	469595.CSAG_01733	1.33e-44	162.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,3WWBY@544|Citrobacter	1236|Gammaproteobacteria	T	Homologues of the ligand binding domain of Tar	tar	GO:0001101,GO:0003674,GO:0004888,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006935,GO:0007154,GO:0007165,GO:0007172,GO:0008150,GO:0009593,GO:0009605,GO:0009719,GO:0009893,GO:0009966,GO:0009987,GO:0010033,GO:0010243,GO:0010604,GO:0010646,GO:0016020,GO:0016021,GO:0016043,GO:0019222,GO:0019899,GO:0019900,GO:0019901,GO:0022607,GO:0023051,GO:0023052,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0032101,GO:0032268,GO:0032270,GO:0032991,GO:0034622,GO:0038023,GO:0040011,GO:0040012,GO:0042221,GO:0042330,GO:0042802,GO:0042803,GO:0043200,GO:0043424,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0046983,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0050920,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051259,GO:0051260,GO:0051606,GO:0051716,GO:0060089,GO:0060255,GO:0065003,GO:0065007,GO:0070887,GO:0071229,GO:0071230,GO:0071310,GO:0071417,GO:0071495,GO:0071840,GO:0071944,GO:0080090,GO:0098561,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901873,GO:1901875	-	ko:K03406,ko:K05875	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,TarH
k59_480760_2	584708.Apau_1994	1.31e-13	74.3	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,3TA0Y@508458|Synergistetes	508458|Synergistetes	C	aldehyde oxidase and xanthine dehydrogenase a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
k59_128362_1	317025.Tcr_1924	2.28e-25	109.0	COG0642@1|root,COG2972@1|root,COG3437@1|root,COG3829@1|root,COG2205@2|Bacteria,COG2972@2|Bacteria,COG3437@2|Bacteria,COG3829@2|Bacteria,1NRP8@1224|Proteobacteria,1T3XA@1236|Gammaproteobacteria,461JT@72273|Thiotrichales	72273|Thiotrichales	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
k59_128366_1	1304883.KI912532_gene1424	4.16e-43	148.0	COG1639@1|root,COG1639@2|Bacteria,1N7EN@1224|Proteobacteria,2VQMM@28216|Betaproteobacteria,2KXRB@206389|Rhodocyclales	206389|Rhodocyclales	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_128366_2	159087.Daro_0623	3.13e-41	139.0	COG0517@1|root,COG0517@2|Bacteria,1N0H3@1224|Proteobacteria,2VRN8@28216|Betaproteobacteria,2KX2P@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
k59_597358_1	1304883.KI912532_gene953	6.09e-75	246.0	COG1629@1|root,COG4771@2|Bacteria,1MW7D@1224|Proteobacteria,2VIV2@28216|Betaproteobacteria,2KVXE@206389|Rhodocyclales	206389|Rhodocyclales	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_771924_1	159087.Daro_0187	1.86e-101	303.0	COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,2VHR0@28216|Betaproteobacteria,2KVR2@206389|Rhodocyclales	206389|Rhodocyclales	T	Domain of unknown function (DUF3391)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3391,HD_5
k59_1066743_1	1179778.PMM47T1_26138	7.91e-32	132.0	COG0784@1|root,COG4251@1|root,COG0784@2|Bacteria,COG4251@2|Bacteria,1NC9X@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07678,ko:K20971	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,DUF2222,HATPase_c,HisKA,Hpt,Response_reg
k59_540267_2	1249480.B649_07925	6.09e-32	120.0	COG1686@1|root,COG1686@2|Bacteria,1MWZA@1224|Proteobacteria,43AWC@68525|delta/epsilon subdivisions,2YT3V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
k59_10944_1	709032.Sulku_1444	7.7e-190	539.0	COG0579@1|root,COG0579@2|Bacteria,1MUCC@1224|Proteobacteria,42M2Q@68525|delta/epsilon subdivisions,2YMYG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Malate quinone- oxidoreductase	mqo	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.1.5.4	ko:K00116	ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00009,M00011	R00360,R00361,R01257	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0086	Mqo
k59_10947_1	1537917.JU82_11385	1.34e-71	229.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42NVA@68525|delta/epsilon subdivisions,2YMYW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
k59_420641_1	709032.Sulku_1366	8.56e-103	317.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,42M6A@68525|delta/epsilon subdivisions,2YMN6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA_synt_2f
k59_1066763_1	1038867.AXAY01000035_gene4455	2.52e-11	69.3	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2TQR7@28211|Alphaproteobacteria,3JWY2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
k59_184970_1	702450.CUW_2679	4.39e-16	83.2	COG2199@1|root,COG3706@2|Bacteria,1UIAV@1239|Firmicutes	1239|Firmicutes	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_1244619_1	1537917.JU82_01520	2.33e-121	357.0	COG2710@1|root,COG2710@2|Bacteria,1MWAJ@1224|Proteobacteria,42M5T@68525|delta/epsilon subdivisions,2YNN6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	cofactor biosynthesis protein NifE	-	-	-	ko:K02587	-	-	-	-	ko00000	-	-	-	Oxidored_nitro
k59_1419832_1	709032.Sulku_2120	4.97e-30	116.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,42MZY@68525|delta/epsilon subdivisions,2YTKV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Bacterial sugar transferase	-	-	2.7.8.6	ko:K00996	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	Bac_transf
k59_1419832_2	1123376.AUIU01000016_gene240	2.83e-37	134.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	wbbL	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glyco_transf_7C,Glycos_transf_2
k59_1184109_1	159087.Daro_1483	8.23e-107	310.0	COG0716@1|root,COG0716@2|Bacteria,1MX7F@1224|Proteobacteria,2VS8P@28216|Betaproteobacteria,2KWPE@206389|Rhodocyclales	206389|Rhodocyclales	C	Low-potential electron donor to a number of redox enzymes	-	-	-	ko:K03839	-	-	-	-	ko00000	-	-	-	Flavodoxin_1
k59_1184109_2	159087.Daro_1484	1.18e-37	127.0	2E0R6@1|root,32W9H@2|Bacteria,1N4U9@1224|Proteobacteria,2VXDJ@28216|Betaproteobacteria,2KXEA@206389|Rhodocyclales	206389|Rhodocyclales	S	NifZ domain	-	-	-	ko:K02597	-	-	-	-	ko00000	-	-	-	NifZ
k59_10979_1	1504672.669787359	2.21e-64	211.0	COG2826@1|root,COG2826@2|Bacteria,1MWI0@1224|Proteobacteria,2VSAV@28216|Betaproteobacteria,4AJAN@80864|Comamonadaceae	28216|Betaproteobacteria	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
k59_67437_1	395493.BegalDRAFT_3260	7.16e-107	319.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,1RPBJ@1236|Gammaproteobacteria,45ZY5@72273|Thiotrichales	72273|Thiotrichales	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
k59_128493_1	709032.Sulku_1762	1.27e-132	392.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2YN8I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Abc transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
k59_128493_2	1249480.B649_03755	9.23e-16	75.5	COG2404@1|root,COG2404@2|Bacteria,1NHB1@1224|Proteobacteria,42NB0@68525|delta/epsilon subdivisions,2YMQ4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	phosphohydrolase (DHH superfamily)	-	-	-	ko:K07097	-	-	-	-	ko00000	-	-	-	DHHA1
k59_10999_1	1121035.AUCH01000002_gene1695	3.29e-96	298.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,2VHEV@28216|Betaproteobacteria,2KU76@206389|Rhodocyclales	206389|Rhodocyclales	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_657585_1	1089552.KI911559_gene263	4.15e-39	148.0	COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,2TRJ9@28211|Alphaproteobacteria,2JPJ7@204441|Rhodospirillales	204441|Rhodospirillales	S	L,D-transpeptidase catalytic domain	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
k59_1009375_1	709032.Sulku_0831	2.17e-165	480.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2YMXZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	ABC transporter, ATP-binding protein	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
k59_1712394_1	642492.Clole_1843	4.95e-09	63.9	COG0270@1|root,COG0270@2|Bacteria,1V3W2@1239|Firmicutes,24HK1@186801|Clostridia	186801|Clostridia	L	Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family	-	-	2.1.1.37	ko:K17398	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko03032,ko03036	-	-	-	DNA_methylase
k59_950491_1	1537917.JU82_03750	4.84e-23	95.5	COG1060@1|root,COG1060@2|Bacteria,1MX50@1224|Proteobacteria,42M6U@68525|delta/epsilon subdivisions,2YN4H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnC	-	1.21.98.1	ko:K11784	ko00130,ko01110,map00130,map01110	-	R08588	RC02329	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
k59_950491_2	1537917.JU82_03755	2.6e-112	335.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,42M74@68525|delta/epsilon subdivisions,2YMI1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Peptidase, M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_1066871_1	709032.Sulku_1385	2.18e-160	469.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,42M9Q@68525|delta/epsilon subdivisions,2YNFG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.20.2.1,1.20.9.1,1.7.7.2	ko:K00367,ko:K00372,ko:K08356	ko00910,ko01120,map00910,map01120	M00531	R00791,R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.6	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_1126766_1	159087.Daro_3457	2.21e-71	229.0	COG1024@1|root,COG1024@2|Bacteria,1NYF6@1224|Proteobacteria,2VPXB@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Enoyl-CoA hydratase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1595163_2	1249480.B649_01435	1.76e-21	89.4	2AIWS@1|root,319ED@2|Bacteria,1Q2HE@1224|Proteobacteria,42VQ7@68525|delta/epsilon subdivisions,2YQ77@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_11039_1	395494.Galf_1857	5.8e-88	271.0	COG2308@1|root,COG2308@2|Bacteria,1P9A0@1224|Proteobacteria,2VISX@28216|Betaproteobacteria,44V9V@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_890735_1	1249480.B649_01165	1.69e-118	357.0	COG0493@1|root,COG1894@1|root,COG0493@2|Bacteria,COG1894@2|Bacteria,1MU2H@1224|Proteobacteria,42M6X@68525|delta/epsilon subdivisions,2YM9W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COGs COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase	-	-	1.17.1.10	ko:K15022	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00377	R00134	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_20,NADH_4Fe-4S,Pyr_redox_2
k59_540443_1	1165841.SULAR_01160	4.26e-50	171.0	COG1231@1|root,COG1231@2|Bacteria,1P3D9@1224|Proteobacteria,42PT0@68525|delta/epsilon subdivisions	1224|Proteobacteria	E	PFAM amine oxidase	-	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase,NAD_binding_8
k59_540444_1	358220.C380_18940	3.15e-44	143.0	2E9SN@1|root,32ZFH@2|Bacteria,1N8MD@1224|Proteobacteria,2VW4H@28216|Betaproteobacteria,4AFFC@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3460)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3460
k59_540444_2	358220.C380_18935	1.14e-42	142.0	COG2913@1|root,COG2913@2|Bacteria,1RBY9@1224|Proteobacteria,2VSW7@28216|Betaproteobacteria,4ADQW@80864|Comamonadaceae	28216|Betaproteobacteria	J	(Lipo)protein	-	-	-	-	-	-	-	-	-	-	-	-	SmpA_OmlA
k59_11941_2	159087.Daro_1964	9.69e-91	274.0	COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,2VK57@28216|Betaproteobacteria,2KV84@206389|Rhodocyclales	206389|Rhodocyclales	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroA	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
k59_1246026_1	640081.Dsui_0999	6.08e-115	337.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,2VKJJ@28216|Betaproteobacteria,2KW6R@206389|Rhodocyclales	206389|Rhodocyclales	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_129835_1	709032.Sulku_2087	4.64e-71	222.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,42MDM@68525|delta/epsilon subdivisions,2YMIV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k59_129835_2	1172190.M947_09560	1.44e-26	102.0	COG2862@1|root,COG2862@2|Bacteria,1NFSW@1224|Proteobacteria,43ACB@68525|delta/epsilon subdivisions,2YT0K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Uncharacterized protein family, UPF0114	-	-	-	-	-	-	-	-	-	-	-	-	UPF0114
k59_68287_1	1249480.B649_01535	8.5e-73	243.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YMHP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF,PAS_9
k59_1421270_1	1249480.B649_04160	3.1e-238	661.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,42MG8@68525|delta/epsilon subdivisions,2YMAP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
k59_1421270_2	1537917.JU82_04410	3.75e-19	80.1	2BS84@1|root,32M9E@2|Bacteria,1Q365@1224|Proteobacteria,42WU4@68525|delta/epsilon subdivisions,2YQWK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1010851_1	62928.azo2809	7.3e-23	91.3	COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,2VU9V@28216|Betaproteobacteria,2KWQT@206389|Rhodocyclales	206389|Rhodocyclales	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
k59_1010851_2	159087.Daro_0611	4.77e-83	246.0	COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,2VU3D@28216|Betaproteobacteria,2KWVI@206389|Rhodocyclales	206389|Rhodocyclales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_1010854_1	640512.BC1003_4717	9.56e-109	327.0	COG0641@1|root,COG0641@2|Bacteria,1MX3M@1224|Proteobacteria,2VYFJ@28216|Betaproteobacteria,1K4C2@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Radical SAM superfamily	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
k59_1360626_1	28072.Nos7524_0686	5.94e-47	171.0	COG0367@1|root,COG0367@2|Bacteria,1G3S7@1117|Cyanobacteria,1HRUE@1161|Nostocales	1117|Cyanobacteria	E	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_421769_3	1348114.OM33_21730	9.6e-14	70.9	COG2303@1|root,COG2303@2|Bacteria,1RH5U@1224|Proteobacteria,1S60X@1236|Gammaproteobacteria,2Q2WF@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	E	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_362479_1	1537917.JU82_11175	1.33e-110	341.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2YMAI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k59_1596203_1	1165841.SULAR_09014	1.91e-46	154.0	COG3150@1|root,COG3150@2|Bacteria,1MVJF@1224|Proteobacteria,42SFN@68525|delta/epsilon subdivisions,2YSYM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Uncharacterised protein family (UPF0227)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0227
k59_1596203_2	387093.SUN_0489	3.49e-44	152.0	COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,42MJ1@68525|delta/epsilon subdivisions,2YMZ8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0212	M20_dimer,Peptidase_M20
k59_658983_1	748247.AZKH_3660	6.12e-69	226.0	COG0642@1|root,COG2205@2|Bacteria,1N1Z2@1224|Proteobacteria,2VPAI@28216|Betaproteobacteria,2KVP3@206389|Rhodocyclales	206389|Rhodocyclales	T	Two-component sensor kinase N-terminal	-	-	2.7.13.3	ko:K07649	ko02020,map02020	M00457	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	2CSK_N,HATPase_c,HisKA
k59_658983_2	748247.AZKH_3659	1.15e-79	241.0	COG0745@1|root,COG0745@2|Bacteria,1MY5Y@1224|Proteobacteria,2VI0W@28216|Betaproteobacteria,2M002@206389|Rhodocyclales	206389|Rhodocyclales	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_1246105_1	1073999.BN137_3370	3.26e-09	56.6	COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria,1RRVF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Type I restriction-modification system methyltransferase subunit	hsdM	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
k59_1246105_2	1387312.BAUS01000004_gene1515	1.38e-77	251.0	COG4096@1|root,COG4096@2|Bacteria,1QTS7@1224|Proteobacteria,2VJSS@28216|Betaproteobacteria,2KKMH@206350|Nitrosomonadales	206350|Nitrosomonadales	L	EcoEI R protein C-terminal	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	EcoEI_R_C,HSDR_N_2,Helicase_C,ResIII
k59_773180_1	1537917.JU82_11355	3.86e-103	320.0	COG1629@1|root,COG4771@2|Bacteria,1QZTU@1224|Proteobacteria,43CNU@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1421348_1	580332.Slit_1340	4.24e-84	271.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria	28216|Betaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
k59_1246124_1	1537917.JU82_02865	2.47e-124	377.0	COG4206@1|root,COG4206@2|Bacteria,1QUGQ@1224|Proteobacteria,42PHJ@68525|delta/epsilon subdivisions,2YNKV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_482343_2	159087.Daro_2430	4.3e-43	149.0	COG1073@1|root,COG1073@2|Bacteria,1R61B@1224|Proteobacteria,2VQGB@28216|Betaproteobacteria,2KW2W@206389|Rhodocyclales	206389|Rhodocyclales	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
k59_1010946_1	709032.Sulku_2657	2.37e-119	364.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42MX5@68525|delta/epsilon subdivisions,2YMSQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)	-	-	2.7.7.13,5.4.2.8	ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II
k59_1772253_1	85643.Tmz1t_0251	1.08e-32	115.0	COG3655@1|root,COG3655@2|Bacteria,1PWHW@1224|Proteobacteria,2WC2F@28216|Betaproteobacteria,2KZK3@206389|Rhodocyclales	206389|Rhodocyclales	K	Cro/C1-type HTH DNA-binding domain	-	-	-	ko:K07727	-	-	-	-	ko00000,ko03000	-	-	-	HTH_26
k59_1033527_1	1249480.B649_01095	1.9e-94	285.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42N1P@68525|delta/epsilon subdivisions,2YP3M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	COG0436 Aspartate tyrosine aromatic aminotransferase	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_679493_1	1249480.B649_10365	1.85e-128	376.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,42M7A@68525|delta/epsilon subdivisions,2YNCK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k59_1147617_1	62928.azo0091	3.7e-08	55.1	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VNJW@28216|Betaproteobacteria,2KW08@206389|Rhodocyclales	206389|Rhodocyclales	NT	Methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
k59_1147617_2	998088.B565_0808	7.88e-31	117.0	COG3338@1|root,COG3338@2|Bacteria,1PEA6@1224|Proteobacteria,1RSM9@1236|Gammaproteobacteria,1Y4ZC@135624|Aeromonadales	135624|Aeromonadales	P	Eukaryotic-type carbonic anhydrase	-	-	4.2.1.1	ko:K01674	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Carb_anhydrase
k59_1033556_1	563040.Saut_1424	3.13e-28	109.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,42PKA@68525|delta/epsilon subdivisions,2YP35@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the protein N5-glutamine methyltransferase family	hemK	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
k59_1033556_2	1537917.JU82_11305	6.54e-82	245.0	2FGS9@1|root,348MQ@2|Bacteria,1P3H2@1224|Proteobacteria,42SDS@68525|delta/epsilon subdivisions,2YPE7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF4149
k59_792138_1	1123518.ARWI01000001_gene688	3.7e-157	447.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,1RMHP@1236|Gammaproteobacteria,45ZTK@72273|Thiotrichales	72273|Thiotrichales	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
k59_1853306_1	1121035.AUCH01000002_gene1605	1.8e-23	95.5	COG0664@1|root,COG0664@2|Bacteria,1RDWC@1224|Proteobacteria,2VR67@28216|Betaproteobacteria,2KWRQ@206389|Rhodocyclales	206389|Rhodocyclales	K	helix_turn_helix, cAMP Regulatory protein	-	-	-	ko:K21555	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2
k59_1853306_2	983917.RGE_22830	4.21e-35	122.0	2E63D@1|root,330SG@2|Bacteria,1N4HX@1224|Proteobacteria,2VTX6@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Is required to sustain N(2)-dependent growth in the presence of low levels of carbon monoxide (CO). Probably acts by protecting the N(2) fixation ability of the nitrogenase complex, which is inactivated in the presence of CO	cowN	-	-	ko:K21694	-	-	-	-	ko00000	-	-	-	-
k59_1266672_1	1131553.JIBI01000002_gene1794	1.91e-52	171.0	COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,2VSHV@28216|Betaproteobacteria,3735J@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
k59_25241_1	90814.KL370891_gene1176	1.99e-11	68.2	COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,1RQQV@1236|Gammaproteobacteria,460ES@72273|Thiotrichales	72273|Thiotrichales	MU	type I secretion outer membrane protein, TolC	-	-	-	ko:K12340,ko:K12538	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00328,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,1.B.17.1,2.A.6.2	-	-	OEP
k59_25241_2	1537917.JU82_06040	1.12e-74	237.0	COG1055@1|root,COG1055@2|Bacteria,1MUX4@1224|Proteobacteria,42MHN@68525|delta/epsilon subdivisions,2YMYK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Involved in arsenical resistance. Thought to form the channel of an arsenite pump	arsB	-	-	ko:K03893	-	-	-	-	ko00000,ko02000	2.A.45.1,3.A.4.1	-	-	ArsB
k59_1315541_1	498761.HM1_3146	9.24e-08	50.1	2DER4@1|root,2ZNXD@2|Bacteria,1W32Q@1239|Firmicutes,24UYB@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_618199_1	709032.Sulku_1615	5.71e-99	295.0	COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,1MXYZ@1224|Proteobacteria,42M4E@68525|delta/epsilon subdivisions,2YMY0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF1722)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
k59_1442271_2	1165841.SULAR_07450	1.19e-108	321.0	COG4974@1|root,COG4974@2|Bacteria,1QU6A@1224|Proteobacteria,42RBN@68525|delta/epsilon subdivisions,2YP23@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_1266716_1	709032.Sulku_2491	2.29e-124	380.0	COG0243@1|root,COG0243@2|Bacteria,1NSXR@1224|Proteobacteria,43BQI@68525|delta/epsilon subdivisions,2YRHF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	ko:K17050	-	-	-	-	ko00000,ko02000	5.A.3.8	-	-	Molybdopterin,Molydop_binding
k59_1612015_1	395494.Galf_1970	3.06e-109	346.0	COG2202@1|root,COG3829@1|root,COG5001@1|root,COG2202@2|Bacteria,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,44WC2@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S)	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,MHYT,PAS_9,dCache_2
k59_679590_1	717773.Thicy_0117	2.46e-35	122.0	COG0048@1|root,COG0048@2|Bacteria,1RCWY@1224|Proteobacteria,1S3WB@1236|Gammaproteobacteria,460JT@72273|Thiotrichales	72273|Thiotrichales	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
k59_679590_2	871585.BDGL_000130	9.98e-35	123.0	COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,1RN77@1236|Gammaproteobacteria,3NM4A@468|Moraxellaceae	1236|Gammaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
k59_1788134_1	1537917.JU82_01000	4.9e-140	409.0	COG1956@1|root,COG3604@1|root,COG1956@2|Bacteria,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,42Y69@68525|delta/epsilon subdivisions,2YNEN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	Transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF_2,HTH_8,Sigma54_activat
k59_1033658_1	159087.Daro_3626	6.14e-71	232.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,2VHNX@28216|Betaproteobacteria,2KV91@206389|Rhodocyclales	28216|Betaproteobacteria	H	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	cbbT	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
k59_1494958_1	1249480.B649_08070	1.02e-64	218.0	COG5001@1|root,COG5001@2|Bacteria,1R4H0@1224|Proteobacteria	1224|Proteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_262241_1	1249480.B649_10180	1.08e-115	340.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,42MFM@68525|delta/epsilon subdivisions,2YMJU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
k59_377095_1	709032.Sulku_1845	2.55e-170	505.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,42MGK@68525|delta/epsilon subdivisions,2YMHU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_262243_1	762966.HMPREF9439_00293	3.6e-36	139.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,2VJ9R@28216|Betaproteobacteria,4PQ3P@995019|Sutterellaceae	28216|Betaproteobacteria	P	Citrate transporter	-	-	-	ko:K11106,ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1,2.A.47.3.3	-	-	Na_sulph_symp
k59_1266745_1	1249480.B649_04225	3.62e-51	170.0	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,42PA2@68525|delta/epsilon subdivisions,2YN18@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
k59_1266745_2	1537917.JU82_04480	1.89e-191	537.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42MTX@68525|delta/epsilon subdivisions,2YMJQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.92	ko:K15895	ko00520,map00520	-	R09825	RC00006,RC00781	ko00000,ko00001,ko01000	-	-	-	DegT_DnrJ_EryC1
k59_1612046_1	583345.Mmol_2178	9.59e-65	208.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VKD8@28216|Betaproteobacteria,2KKE1@206350|Nitrosomonadales	206350|Nitrosomonadales	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activ_2
k59_204180_1	1165841.SULAR_09054	2.79e-201	570.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,42M90@68525|delta/epsilon subdivisions,2YMR5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k59_1671497_1	537970.HCAN_0662	1.25e-136	412.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,42MEI@68525|delta/epsilon subdivisions	1224|Proteobacteria	E	asparagine synthase, glutamine-hydrolyzing	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_1494978_1	926550.CLDAP_19490	0.000167	49.3	COG1319@1|root,COG2931@1|root,COG3420@1|root,COG1319@2|Bacteria,COG2931@2|Bacteria,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	FAD_binding_5
k59_1788171_1	662755.CRES_2115	8.08e-07	53.9	COG1414@1|root,COG1414@2|Bacteria,2GM23@201174|Actinobacteria,22K71@1653|Corynebacteriaceae	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
k59_501297_1	580332.Slit_0426	8.81e-54	189.0	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,2VI5J@28216|Betaproteobacteria,44W58@713636|Nitrosomonadales	28216|Betaproteobacteria	M	AsmA family	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA,AsmA_2
k59_850179_1	640081.Dsui_0283	9.61e-38	138.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,2VIW1@28216|Betaproteobacteria,2KUH8@206389|Rhodocyclales	206389|Rhodocyclales	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groEL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_1853450_1	717772.THIAE_05065	3.44e-140	421.0	COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,1RNGY@1236|Gammaproteobacteria,45ZRS@72273|Thiotrichales	72273|Thiotrichales	C	TIGRFAM nitrite reductase NAD(P)H , large subunit	-	-	1.7.1.15	ko:K00362	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2
k59_792333_1	709032.Sulku_2437	2.28e-12	66.2	COG2220@1|root,COG2220@2|Bacteria,1MV20@1224|Proteobacteria,42QPP@68525|delta/epsilon subdivisions,2YP9R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
k59_792333_2	709032.Sulku_2438	4.84e-85	254.0	COG2353@1|root,COG2353@2|Bacteria,1PDM9@1224|Proteobacteria,42TFW@68525|delta/epsilon subdivisions,2YQ0K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
k59_792333_3	1537917.JU82_02250	1.34e-28	111.0	2AIAA@1|root,318R4@2|Bacteria,1Q0T4@1224|Proteobacteria,42SFV@68525|delta/epsilon subdivisions,2YPR6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	1.13.11.63	ko:K21817	-	-	-	-	ko00000,ko01000	-	-	-	-
k59_377143_1	930169.B5T_02380	8.76e-67	215.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,1RN9N@1236|Gammaproteobacteria,1XH3A@135619|Oceanospirillales	135619|Oceanospirillales	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
k59_1033764_1	709032.Sulku_2190	4.28e-118	351.0	COG1866@1|root,COG1866@2|Bacteria,1MWXN@1224|Proteobacteria,42N5Y@68525|delta/epsilon subdivisions,2YN1U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
k59_1853490_1	90814.KL370891_gene846	7.69e-40	145.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1SYRX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Protoglobin
k59_204266_1	709032.Sulku_0098	3.53e-228	629.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,42KZT@68525|delta/epsilon subdivisions,2YMNC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
k59_316476_1	582744.Msip34_1226	5.03e-119	354.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,2VHNG@28216|Betaproteobacteria,2KKEQ@206350|Nitrosomonadales	206350|Nitrosomonadales	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
k59_679726_1	159087.Daro_3894	7.56e-149	431.0	COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,2VITS@28216|Betaproteobacteria,2KUA4@206389|Rhodocyclales	206389|Rhodocyclales	L	Belongs to the DNA photolyase family	phrB	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
k59_909830_1	660470.Theba_0103	1.8e-25	112.0	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria	2|Bacteria	T	Histidine kinase	luxQ	GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0140096,GO:1901564	2.7.13.3	ko:K07678,ko:K07716,ko:K10909	ko02020,ko02024,ko02025,ko02026,ko04112,ko05111,map02020,map02024,map02025,map02026,map04112,map05111	M00475,M00511,M00513	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Hpt,LuxQ-periplasm,PAS_9,Response_reg,dCache_1
k59_1673518_2	1537917.JU82_02965	1.43e-11	63.5	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,42MWK@68525|delta/epsilon subdivisions,2YMIH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
k59_1562539_1	1537917.JU82_07210	2.14e-46	154.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,42PSG@68525|delta/epsilon subdivisions,2YMFJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
k59_1562539_2	1249480.B649_07500	8.2e-50	167.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,42NJ0@68525|delta/epsilon subdivisions,2YM9A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
k59_851854_1	1286171.EAL2_808p07480	1.56e-66	219.0	COG1387@1|root,COG1387@2|Bacteria,1TQ33@1239|Firmicutes,249TZ@186801|Clostridia	186801|Clostridia	E	PHP domain protein	polX	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
k59_851858_1	1537917.JU82_07005	2.13e-98	295.0	COG1536@1|root,COG1536@2|Bacteria,1MV9X@1224|Proteobacteria,42MS3@68525|delta/epsilon subdivisions,2YM90@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar motor switch protein	fliG	GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
k59_1036740_1	709032.Sulku_2036	2.69e-34	126.0	COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,42MMJ@68525|delta/epsilon subdivisions,2YMJ0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KO	Hydrogenase	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
k59_1036740_2	1249480.B649_09520	2.57e-29	109.0	COG2215@1|root,COG2215@2|Bacteria,1Q5AP@1224|Proteobacteria,42R81@68525|delta/epsilon subdivisions,2YP06@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the NiCoT transporter (TC 2.A.52) family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1673552_1	1249480.B649_01565	1.33e-59	194.0	COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,42QJ2@68525|delta/epsilon subdivisions,2YNBV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COGs COG3864 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
k59_1673552_2	709032.Sulku_0346	2.17e-19	86.3	COG0507@1|root,COG0507@2|Bacteria,1QCFP@1224|Proteobacteria,42NH5@68525|delta/epsilon subdivisions,2YMK5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member	-	-	-	-	-	-	-	-	-	-	-	-	Herpes_Helicase,PIF1
k59_1203170_1	1132855.KB913035_gene1916	8.04e-73	228.0	COG1940@1|root,COG1940@2|Bacteria,1MU94@1224|Proteobacteria,2VMGT@28216|Betaproteobacteria,2KKT2@206350|Nitrosomonadales	206350|Nitrosomonadales	GK	PFAM ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
k59_1203170_2	580332.Slit_1455	4.51e-17	80.5	COG0834@1|root,COG2203@1|root,COG5001@1|root,COG0834@2|Bacteria,COG2203@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,44WBU@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Diguanylate cyclase phosphodiesterase with PAS PAC and GAF sensor(S)	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS,PAS_4,PAS_9,SBP_bac_3
k59_1203175_1	1165841.SULAR_03467	3.21e-53	179.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,42MA7@68525|delta/epsilon subdivisions,2YMTP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
k59_1203175_2	1249480.B649_10750	3.15e-12	68.2	COG0387@1|root,COG0387@2|Bacteria,1N1MR@1224|Proteobacteria,42MUQ@68525|delta/epsilon subdivisions,2YMUB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Sodium calcium exchanger membrane	-	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
k59_379092_2	1295642.H839_01406	1.02e-09	64.3	COG0010@1|root,COG0010@2|Bacteria,1V6Y2@1239|Firmicutes,4HHTQ@91061|Bacilli,1WERJ@129337|Geobacillus	91061|Bacilli	E	Arginase family	-	-	-	-	-	-	-	-	-	-	-	-	Arginase
k59_1562650_1	709032.Sulku_0906	3.39e-253	704.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MQ0@68525|delta/epsilon subdivisions,2YN57@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1203223_1	1442598.JABW01000022_gene2028	8.02e-103	307.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,42MWH@68525|delta/epsilon subdivisions,2YMPE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	epimerase dehydratase family	-	-	5.1.3.2,5.1.3.6	ko:K01784,ko:K08679	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R01385,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
k59_565707_1	1304883.KI912532_gene2034	1.19e-45	155.0	COG0042@1|root,COG0042@2|Bacteria,1MUSM@1224|Proteobacteria,2VHWD@28216|Betaproteobacteria,2KVTR@206389|Rhodocyclales	206389|Rhodocyclales	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs	dusC	-	-	ko:K05541	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
k59_565707_2	1304883.KI912532_gene2033	8.45e-57	179.0	COG1569@1|root,COG1569@2|Bacteria,1NASM@1224|Proteobacteria,2VVUB@28216|Betaproteobacteria,2KX9H@206389|Rhodocyclales	206389|Rhodocyclales	S	nucleic acid-binding protein, contains PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
k59_1150291_1	1249480.B649_11065	8.13e-116	345.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42MFK@68525|delta/epsilon subdivisions,2YN87@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Abc transporter	nikZ	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k59_1203263_1	1122236.KB905143_gene182	2.6e-58	194.0	COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,2VIPV@28216|Betaproteobacteria,2KMA4@206350|Nitrosomonadales	206350|Nitrosomonadales	P	) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
k59_1445289_1	1304883.KI912532_gene1717	4.89e-116	347.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,2VIE0@28216|Betaproteobacteria,2KUDK@206389|Rhodocyclales	206389|Rhodocyclales	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_5
k59_503528_1	1165841.SULAR_04317	6.08e-116	340.0	COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,42NEN@68525|delta/epsilon subdivisions,2YN4D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k59_565768_1	1123518.ARWI01000001_gene1995	6.15e-110	349.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,45ZPF@72273|Thiotrichales	72273|Thiotrichales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_973209_1	1172190.M947_08360	3.06e-41	149.0	COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,42M3J@68525|delta/epsilon subdivisions,2YMF8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
k59_84389_1	754477.Q7C_714	7.67e-15	75.9	COG2825@1|root,COG2825@2|Bacteria,1RD8X@1224|Proteobacteria,1RQIE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the skp family	skp	GO:0001530,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0006807,GO:0008104,GO:0008150,GO:0008152,GO:0008289,GO:0009279,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0019867,GO:0022417,GO:0022607,GO:0030288,GO:0030312,GO:0030313,GO:0031647,GO:0031975,GO:0032978,GO:0033036,GO:0034613,GO:0042597,GO:0042802,GO:0043163,GO:0043165,GO:0043170,GO:0044085,GO:0044091,GO:0044238,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0050821,GO:0051082,GO:0051179,GO:0051205,GO:0051234,GO:0051604,GO:0051641,GO:0061024,GO:0061077,GO:0065007,GO:0065008,GO:0070727,GO:0071704,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0097367,GO:1901564	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
k59_1673684_1	1249480.B649_09050	8.33e-82	266.0	COG0457@1|root,COG0457@2|Bacteria,1QV15@1224|Proteobacteria,42NKI@68525|delta/epsilon subdivisions,2YMKG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	COG0457 FOG TPR repeat	pflB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_6,TPR_8
k59_1088002_1	452637.Oter_4633	2.95e-08	61.6	COG0750@1|root,COG0750@2|Bacteria,46S9B@74201|Verrucomicrobia,3K73Q@414999|Opitutae	414999|Opitutae	M	zinc metalloprotease	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
k59_84397_1	709032.Sulku_0055	5.49e-63	207.0	COG3144@1|root,COG3144@2|Bacteria,1PBUJ@1224|Proteobacteria,42VQM@68525|delta/epsilon subdivisions,2YQGT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Flagellar hook-length control protein FliK	-	-	-	-	-	-	-	-	-	-	-	-	Flg_hook
k59_1497007_1	1304883.KI912532_gene2543	5.37e-142	404.0	COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,2VIHE@28216|Betaproteobacteria,2KV9V@206389|Rhodocyclales	206389|Rhodocyclales	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_973229_1	709032.Sulku_0658	2.95e-105	325.0	COG2199@1|root,COG2199@2|Bacteria,1QTZT@1224|Proteobacteria,43E8E@68525|delta/epsilon subdivisions,2YN2B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_379202_1	1123518.ARWI01000001_gene1563	1.48e-52	181.0	COG1168@1|root,COG1168@2|Bacteria,1MY33@1224|Proteobacteria,1RP58@1236|Gammaproteobacteria,460EN@72273|Thiotrichales	72273|Thiotrichales	E	PFAM Aminotransferase class I and II	-	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_910053_1	202954.BBNK01000034_gene3794	1.35e-35	124.0	2A3Q7@1|root,30S7S@2|Bacteria,1NP2K@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_27193_1	1249480.B649_11505	1.1e-30	109.0	COG2921@1|root,COG2921@2|Bacteria,1Q61Q@1224|Proteobacteria,42WSH@68525|delta/epsilon subdivisions,2YQB4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the UPF0250 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF493
k59_1171369_1	555778.Hneap_2222	4.09e-56	197.0	COG2199@1|root,COG2202@1|root,COG3447@1|root,COG3614@1|root,COG2199@2|Bacteria,COG2202@2|Bacteria,COG3447@2|Bacteria,COG3614@2|Bacteria,1NWNJ@1224|Proteobacteria,1T2J6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	PAS sensor protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GAF_2,GGDEF,HATPase_c,HisKA,MASE1,MHYT,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_1222823_2	1095743.HMPREF1054_1956	8.59e-27	102.0	COG5566@1|root,COG5566@2|Bacteria,1RIK6@1224|Proteobacteria,1S2CF@1236|Gammaproteobacteria,1Y910@135625|Pasteurellales	135625|Pasteurellales	S	Mor transcription activator family	-	-	-	-	-	-	-	-	-	-	-	-	Mor
k59_398494_1	1537917.JU82_06625	2e-53	170.0	COG0802@1|root,COG0802@2|Bacteria,1Q97W@1224|Proteobacteria,42TIG@68525|delta/epsilon subdivisions,2YPKI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	ATPase or kinase	tsaE	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
k59_398494_2	1249480.B649_07355	2.78e-92	274.0	COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,42M4J@68525|delta/epsilon subdivisions,2YMZ4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	ABC transporter, ATP-binding protein	lptB	-	-	ko:K01990,ko:K06861	ko02010,map02010	M00254,M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1,3.A.1	-	-	ABC_tran,BCA_ABC_TP_C
k59_1107198_1	1249480.B649_00370	1e-72	221.0	COG2077@1|root,COG2077@2|Bacteria,1RAJ9@1224|Proteobacteria,42RE8@68525|delta/epsilon subdivisions,2YP3Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	tpx	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	Redoxin
k59_585754_1	1158150.KB906242_gene210	8.55e-87	271.0	COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1QWI1@1224|Proteobacteria,1RZ7K@1236|Gammaproteobacteria,1X1UJ@135613|Chromatiales	135613|Chromatiales	L	Toprim-like	-	-	3.6.4.12	ko:K17680	-	-	-	-	ko00000,ko01000,ko03029	-	-	-	DnaB_C
k59_45639_1	1249480.B649_06585	9.66e-127	365.0	COG0454@1|root,COG0456@2|Bacteria,1Q9FS@1224|Proteobacteria,42YQT@68525|delta/epsilon subdivisions,2YRH5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
k59_1289384_1	243233.MCA0138	1.24e-94	289.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,1RMW8@1236|Gammaproteobacteria,1XDX9@135618|Methylococcales	135618|Methylococcales	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
k59_1584463_1	1121937.AUHJ01000009_gene1523	9.58e-05	46.2	COG0726@1|root,COG0726@2|Bacteria,1MWMZ@1224|Proteobacteria,1RREJ@1236|Gammaproteobacteria,4663C@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	xylanase chitin deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3473,Polysacc_deac_1
k59_1584463_2	1537917.JU82_09600	7.81e-41	135.0	2C0BV@1|root,300E8@2|Bacteria,1Q68S@1224|Proteobacteria,432Q2@68525|delta/epsilon subdivisions,2YSMD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_170574_1	1249480.B649_10925	2.44e-92	277.0	2A4YW@1|root,30TKN@2|Bacteria,1PDH4@1224|Proteobacteria,42SHS@68525|delta/epsilon subdivisions,2YPG5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_459082_1	1123392.AQWL01000002_gene2035	3.28e-82	250.0	COG0842@1|root,COG0842@2|Bacteria,1N55T@1224|Proteobacteria,2VJ7R@28216|Betaproteobacteria,1KRKR@119069|Hydrogenophilales	119069|Hydrogenophilales	V	ABC-2 type transporter	-	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
k59_933052_1	1122970.AUHC01000011_gene2678	2.14e-58	196.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,2TSJ5@28211|Alphaproteobacteria,2K3ZY@204457|Sphingomonadales	204457|Sphingomonadales	P	Ring hydroxylating alpha subunit (catalytic domain)	-	-	1.14.15.7	ko:K00499	ko00260,map00260	-	R07409	RC00087	ko00000,ko00001,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
k59_284112_1	265072.Mfla_0995	2.3e-88	266.0	COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,2VIRB@28216|Betaproteobacteria,2KM03@206350|Nitrosomonadales	206350|Nitrosomonadales	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
k59_1584515_1	1249480.B649_11105	2.65e-83	252.0	2AI9D@1|root,318Q0@2|Bacteria,1Q0R3@1224|Proteobacteria,42SDN@68525|delta/epsilon subdivisions,2YP0E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1584515_2	1249480.B649_11100	7.4e-83	248.0	COG5456@1|root,COG5456@2|Bacteria,1Q27X@1224|Proteobacteria,42V4G@68525|delta/epsilon subdivisions,2YQE8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	FixH	-	-	-	-	-	-	-	-	-	-	-	-	FixH,YtkA
k59_1171484_2	717773.Thicy_1118	6.42e-27	104.0	COG0664@1|root,COG0664@2|Bacteria,1NBRS@1224|Proteobacteria,1T0IJ@1236|Gammaproteobacteria,462MB@72273|Thiotrichales	72273|Thiotrichales	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	cNMP_binding
k59_521970_1	1304284.L21TH_0226	5.93e-33	128.0	COG0531@1|root,COG0531@2|Bacteria,1TZQ6@1239|Firmicutes,24EQ1@186801|Clostridia,36UB3@31979|Clostridiaceae	186801|Clostridia	E	Spore germination protein	-	-	-	ko:K06296,ko:K06311	-	-	-	-	ko00000,ko02000	2.A.3.9.3,2.A.3.9.4	-	-	Spore_permease
k59_1339578_1	326298.Suden_1440	7.66e-81	265.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YM96@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	cmeF	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_1107315_1	159087.Daro_3119	1.46e-65	210.0	COG0538@1|root,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,2VHVD@28216|Betaproteobacteria,2KUTI@206389|Rhodocyclales	206389|Rhodocyclales	C	Isocitrate/isopropylmalate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
k59_284186_1	90814.KL370891_gene1053	2.91e-106	335.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,1RN03@1236|Gammaproteobacteria,45ZYT@72273|Thiotrichales	72273|Thiotrichales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_1399638_1	1249480.B649_04795	1.06e-108	338.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2YMQV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_1584610_1	1123517.JOMR01000001_gene823	4.8e-87	269.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,1RNEW@1236|Gammaproteobacteria,45ZQU@72273|Thiotrichales	72273|Thiotrichales	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
k59_459222_1	1249480.B649_09435	6.67e-138	413.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42Z31@68525|delta/epsilon subdivisions,2YRAR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Hpt sensor hybrid histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
k59_1399670_1	1121035.AUCH01000004_gene245	9.87e-80	244.0	COG2169@1|root,COG2169@2|Bacteria,1QTXR@1224|Proteobacteria,2WGQ9@28216|Betaproteobacteria,2KZW4@206389|Rhodocyclales	206389|Rhodocyclales	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
k59_933221_1	1304883.KI912532_gene1916	2.87e-55	180.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,2VIVG@28216|Betaproteobacteria,2KV71@206389|Rhodocyclales	206389|Rhodocyclales	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k59_933221_2	159087.Daro_3033	7.83e-43	150.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,2VHEB@28216|Betaproteobacteria,2KUN2@206389|Rhodocyclales	206389|Rhodocyclales	E	acetylornithine aminotransferase	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_459244_1	1537917.JU82_09860	6.47e-87	267.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,42MMY@68525|delta/epsilon subdivisions,2YMDM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	dihydropteroate synthase	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
k59_1107403_1	1537917.JU82_02805	1.61e-49	160.0	COG1393@1|root,COG1393@2|Bacteria,1QDI7@1224|Proteobacteria,42U8X@68525|delta/epsilon subdivisions,2YPXC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	ArsC
k59_1107403_2	1537917.JU82_02800	2.78e-32	114.0	COG0721@1|root,COG0721@2|Bacteria,1Q61J@1224|Proteobacteria,42VIQ@68525|delta/epsilon subdivisions,2YQAY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
k59_337164_2	709032.Sulku_0325	1.55e-49	172.0	COG2198@1|root,COG2198@2|Bacteria,1PCKH@1224|Proteobacteria,42W9Z@68525|delta/epsilon subdivisions,2YQ6K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1399682_1	1234364.AMSF01000016_gene1508	6.04e-120	353.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,1RP9Z@1236|Gammaproteobacteria,1X4QY@135614|Xanthomonadales	135614|Xanthomonadales	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k59_102129_1	387093.SUN_1915	5.73e-22	95.1	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,42NF8@68525|delta/epsilon subdivisions,2YMBT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	ATP-dependent DNA helicase	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
k59_102129_2	387093.SUN_1916	1.03e-40	145.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,42M74@68525|delta/epsilon subdivisions,2YMI1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Peptidase, M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_585981_1	1249480.B649_00295	9.25e-19	78.2	2BTPW@1|root,32NWY@2|Bacteria,1Q3ZS@1224|Proteobacteria,42Y1G@68525|delta/epsilon subdivisions,2YQR3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Uncharacterized conserved protein (DUF2249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2249
k59_585981_2	1537917.JU82_10055	4.01e-73	222.0	COG3945@1|root,COG3945@2|Bacteria,1N383@1224|Proteobacteria,43CMM@68525|delta/epsilon subdivisions,2YTEH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
k59_1399699_1	449673.BACSTE_00848	8.62e-15	77.0	2ARHX@1|root,31GUA@2|Bacteria,4PK5R@976|Bacteroidetes,2FU29@200643|Bacteroidia,4AVR9@815|Bacteroidaceae	976|Bacteroidetes	S	Bacteriophage abortive infection AbiH	-	-	-	-	-	-	-	-	-	-	-	-	AbiH
k59_1465506_1	1249480.B649_08880	3.62e-73	234.0	28NUA@1|root,2ZBSQ@2|Bacteria,1QE31@1224|Proteobacteria,42Z7U@68525|delta/epsilon subdivisions,2YR9R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1289592_1	929558.SMGD1_0381	2.86e-56	177.0	COG0745@1|root,COG0745@2|Bacteria,1RHDD@1224|Proteobacteria,42SAC@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	PFAM response regulator receiver	cheY34H-1	-	2.7.13.3	ko:K03407,ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	Response_reg
k59_459308_1	709032.Sulku_1561	3.73e-123	355.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,42NJE@68525|delta/epsilon subdivisions,2YM8V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
k59_1289620_1	522772.Dacet_2328	1.12e-57	200.0	COG2199@1|root,COG2200@1|root,COG4564@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,COG4564@2|Bacteria,2GFIK@200930|Deferribacteres	200930|Deferribacteres	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_1339765_1	709032.Sulku_2071	1.8e-114	335.0	COG2899@1|root,COG2899@2|Bacteria,1NURT@1224|Proteobacteria,42MRA@68525|delta/epsilon subdivisions,2YNAM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF475)	-	-	-	ko:K09799	-	-	-	-	ko00000	-	-	-	DUF475
k59_586068_2	536232.CLM_1658	2.29e-19	85.9	COG0740@1|root,COG0740@2|Bacteria,1TR2H@1239|Firmicutes,249NC@186801|Clostridia,36DUJ@31979|Clostridiaceae	186801|Clostridia	OU	Belongs to the peptidase S14 family	-	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
k59_102184_2	929558.SMGD1_1142	8.16e-20	90.9	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,42MIH@68525|delta/epsilon subdivisions,2YR84@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing EAL and modified HD-GYP domains	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
k59_1756123_1	1165841.SULAR_09219	5.73e-136	391.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,42NX0@68525|delta/epsilon subdivisions,2YMHX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Membrane protease subunits	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_48156_2	709032.Sulku_1004	1.66e-75	227.0	COG0347@1|root,COG0347@2|Bacteria	2|Bacteria	K	Belongs to the P(II) protein family	glnB	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
k59_1520356_2	1537917.JU82_06275	9.03e-229	645.0	COG4753@1|root,COG4753@2|Bacteria,1Q8YM@1224|Proteobacteria,42YGW@68525|delta/epsilon subdivisions,2YR37@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_1110398_1	765913.ThidrDRAFT_2128	2.34e-46	162.0	COG1808@1|root,COG1808@2|Bacteria,1NMS3@1224|Proteobacteria,1RRTC@1236|Gammaproteobacteria,1WWHR@135613|Chromatiales	135613|Chromatiales	I	Domain of unknown function (DUF389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
k59_747293_1	666681.M301_0144	3.08e-17	80.9	COG0457@1|root,COG0457@2|Bacteria,1RKBG@1224|Proteobacteria,2VQFW@28216|Betaproteobacteria,2KMV8@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_747293_2	583345.Mmol_0244	4.45e-31	120.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,2KKZR@206350|Nitrosomonadales	206350|Nitrosomonadales	NU	General secretory system II protein E domain protein	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
k59_287466_1	749222.Nitsa_1244	7.57e-46	154.0	COG1853@1|root,COG1853@2|Bacteria,1PD46@1224|Proteobacteria,42T15@68525|delta/epsilon subdivisions,2YPFK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COG1853 Conserved protein domain typically associated with flavoprotein	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
k59_643946_1	159087.Daro_0429	1.58e-82	248.0	COG0745@1|root,COG0745@2|Bacteria,1MY5Y@1224|Proteobacteria,2VI0W@28216|Betaproteobacteria,2KUBI@206389|Rhodocyclales	206389|Rhodocyclales	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K02483,ko:K07774	ko02020,map02020	M00457	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_819114_1	159087.Daro_1427	7.65e-26	105.0	COG0804@1|root,COG0804@2|Bacteria,1MU5P@1224|Proteobacteria,2VJYX@28216|Betaproteobacteria,2KUE8@206389|Rhodocyclales	206389|Rhodocyclales	E	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family	ureC	-	3.5.1.5	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Urease_alpha
k59_819114_2	1121035.AUCH01000023_gene3423	1.13e-92	273.0	COG2371@1|root,COG2371@2|Bacteria,1MZQZ@1224|Proteobacteria,2VMRF@28216|Betaproteobacteria,2KWN7@206389|Rhodocyclales	206389|Rhodocyclales	O	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly	ureE	-	-	ko:K03187	-	-	-	-	ko00000	-	-	-	UreE_C,UreE_N
k59_1342681_1	713587.THITH_12525	1.18e-36	144.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1WVYT@135613|Chromatiales	135613|Chromatiales	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,PAS_4,Response_reg
k59_174146_2	709032.Sulku_0379	1.14e-77	244.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,42NGE@68525|delta/epsilon subdivisions,2YN37@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0471 Di- and tricarboxylate	-	-	-	ko:K03319	-	-	-	-	ko00000	2.A.47	-	-	Na_sulph_symp
k59_340262_1	1218074.BAXZ01000025_gene4546	4.09e-52	177.0	COG4261@1|root,COG4261@2|Bacteria,1MVXJ@1224|Proteobacteria,2VHP0@28216|Betaproteobacteria,1K0GB@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Bacterial lipid A biosynthesis acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Lip_A_acyltrans
k59_104644_2	1249480.B649_00085	1.33e-59	198.0	COG0617@1|root,COG1418@1|root,COG0617@2|Bacteria,COG1418@2|Bacteria,1MU2X@1224|Proteobacteria,42MJJ@68525|delta/epsilon subdivisions,2YMGU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	tRNA nucleotidyltransferase poly(A) polymerase	cca	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
k59_1520455_1	159087.Daro_3107	2.14e-90	287.0	COG3829@1|root,COG4191@1|root,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VI6T@28216|Betaproteobacteria,2KUQP@206389|Rhodocyclales	206389|Rhodocyclales	T	COG2202 FOG PAS PAC domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9
k59_1756231_1	709032.Sulku_0824	4.48e-56	181.0	COG1226@1|root,COG1226@2|Bacteria,1R0RZ@1224|Proteobacteria,42UWU@68525|delta/epsilon subdivisions,2YQ24@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	TrkA-N domain	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	TrkA_C,TrkA_N
k59_1756231_2	709032.Sulku_0823	3.92e-06	48.5	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,42MW6@68525|delta/epsilon subdivisions,2YNJR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	potassium channel protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans,Ion_trans_2,TrkA_C,TrkA_N
k59_1756249_1	709032.Sulku_1737	1.62e-14	71.6	COG2177@1|root,COG2177@2|Bacteria,1R85B@1224|Proteobacteria,42PX3@68525|delta/epsilon subdivisions,2YNQW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Cell division protein FtsX	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	-
k59_1756249_2	1249480.B649_03860	4.94e-65	211.0	COG4942@1|root,COG4942@2|Bacteria,1QV6K@1224|Proteobacteria,42M9V@68525|delta/epsilon subdivisions,2YMS7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_524722_1	395494.Galf_1748	1.83e-143	428.0	COG1629@1|root,COG4771@2|Bacteria,1MW7D@1224|Proteobacteria,2VIV2@28216|Betaproteobacteria,44WKC@713636|Nitrosomonadales	28216|Betaproteobacteria	M	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_819216_2	709032.Sulku_1050	1.36e-55	175.0	2BTNN@1|root,32NVN@2|Bacteria,1PA2W@1224|Proteobacteria,42Y0V@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Phospholipase_D-nuclease N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N
k59_1225896_1	395494.Galf_1704	1.59e-38	139.0	COG0709@1|root,COG0709@2|Bacteria,1MWFG@1224|Proteobacteria,2VJSD@28216|Betaproteobacteria,44VM5@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C,Pyr_redox_2
k59_302235_1	1537917.JU82_00680	1.69e-27	107.0	COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,42R7K@68525|delta/epsilon subdivisions,2YP16@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
k59_302235_2	1537917.JU82_00685	3.01e-128	375.0	COG1797@1|root,COG1797@2|Bacteria,1MV7Z@1224|Proteobacteria,42M8T@68525|delta/epsilon subdivisions	1224|Proteobacteria	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_0470	AAA_26,CbiA,GATase_3
k59_1420096_1	207954.MED92_08126	7.29e-111	348.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,1XIHS@135619|Oceanospirillales	135619|Oceanospirillales	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_1126923_2	709032.Sulku_0127	4.44e-126	363.0	COG3665@1|root,COG3665@2|Bacteria,1N2KR@1224|Proteobacteria,42S17@68525|delta/epsilon subdivisions,2YPCG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function (DUF1989)	-	-	-	ko:K09967	-	-	-	-	ko00000	-	-	-	DUF1989
k59_657766_1	709032.Sulku_2181	2.01e-140	402.0	COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,42MBW@68525|delta/epsilon subdivisions,2YMVQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	ribonuclease BN	rbn	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
k59_361533_3	709032.Sulku_1615	6.65e-27	106.0	COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,1MXYZ@1224|Proteobacteria,42M4E@68525|delta/epsilon subdivisions,2YMY0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF1722)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
k59_1420099_1	159087.Daro_0925	3.69e-193	545.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VIE9@28216|Betaproteobacteria,2KUR5@206389|Rhodocyclales	206389|Rhodocyclales	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,cNMP_binding
k59_772167_1	1123393.KB891316_gene1612	1.4e-41	154.0	COG3637@1|root,COG5338@1|root,COG3637@2|Bacteria,COG5338@2|Bacteria,1PFWT@1224|Proteobacteria	1224|Proteobacteria	M	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	BBP2_2,OMP_b-brl
k59_481125_1	1121267.JHZL01000001_gene623	3.31e-22	97.8	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,42M62@68525|delta/epsilon subdivisions,2YMKY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Capsular polysaccharide ABC transporter, periplasmic polysaccharide-binding protein	kpsD	-	-	-	-	-	-	-	-	-	-	-	Poly_export,SLBB
k59_481125_2	1499680.CCFE01000030_gene3652	1.05e-13	70.9	COG3551@1|root,COG3551@2|Bacteria,1UBTU@1239|Firmicutes,4IN93@91061|Bacilli,1ZN23@1386|Bacillus	91061|Bacilli	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1654032_1	1249480.B649_09470	9.36e-82	253.0	COG0840@1|root,COG0840@2|Bacteria,1PNV4@1224|Proteobacteria,42YFX@68525|delta/epsilon subdivisions,2YRME@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
k59_361541_1	709032.Sulku_2617	1.62e-59	186.0	COG3829@1|root,COG3829@2|Bacteria,1RH32@1224|Proteobacteria,42RWQ@68525|delta/epsilon subdivisions,2YP4B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	PAS domain	-	-	-	ko:K03776	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	PAS_3
k59_361541_2	709032.Sulku_2616	7.46e-25	95.9	COG3062@1|root,COG3062@2|Bacteria,1NGMR@1224|Proteobacteria,42UEZ@68525|delta/epsilon subdivisions,2YPWT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	nitrate reductase	napD	-	-	ko:K02570	-	-	-	-	ko00000	-	-	-	NapD
k59_1009560_2	709032.Sulku_1225	2.98e-56	191.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42MH9@68525|delta/epsilon subdivisions,2YMWG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	COG1459 Type II secretory pathway, component PulF	-	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
k59_11144_1	85643.Tmz1t_2971	2.08e-85	274.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,2VJ61@28216|Betaproteobacteria,2KXRI@206389|Rhodocyclales	206389|Rhodocyclales	S	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_657787_1	1249480.B649_06430	4.39e-34	122.0	COG0745@1|root,COG0745@2|Bacteria,1PFGE@1224|Proteobacteria,42U08@68525|delta/epsilon subdivisions,2YPVW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_657787_2	1249480.B649_06435	5.25e-73	231.0	COG3437@1|root,COG4753@1|root,COG3437@2|Bacteria,COG4753@2|Bacteria,1QUN9@1224|Proteobacteria,42PB6@68525|delta/epsilon subdivisions,2YTKF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,PAS_9,Response_reg
k59_890869_1	1304883.KI912532_gene267	2.34e-75	229.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2VIT4@28216|Betaproteobacteria,2KUNU@206389|Rhodocyclales	206389|Rhodocyclales	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_890869_2	159087.Daro_3568	1.07e-45	160.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,2VIBV@28216|Betaproteobacteria,2KVEJ@206389|Rhodocyclales	206389|Rhodocyclales	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3329,HATPase_c,HisKA,PAS_8
k59_11149_1	387093.SUN_1349	3.34e-94	280.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	enhA_1	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
k59_11149_2	1165841.SULAR_00950	1.54e-09	57.8	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,42MEM@68525|delta/epsilon subdivisions,2YMWQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
k59_302268_1	768706.Desor_4030	4.34e-44	164.0	COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,26021@186807|Peptococcaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_4,PAS_8,PAS_9
k59_1538104_1	395494.Galf_0345	1.26e-83	271.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,2VHDH@28216|Betaproteobacteria,44V1H@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k59_1009595_1	1502770.JQMG01000001_gene1736	2.74e-19	85.9	COG4965@1|root,COG4965@2|Bacteria,1RDNH@1224|Proteobacteria,2VRA2@28216|Betaproteobacteria,2KMPP@206350|Nitrosomonadales	206350|Nitrosomonadales	U	Type II secretion system (T2SS), protein F	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
k59_1009595_2	381666.H16_A0709	9.92e-11	64.3	COG2064@1|root,COG2064@2|Bacteria,1MWAZ@1224|Proteobacteria,2VIA4@28216|Betaproteobacteria,1K07H@119060|Burkholderiaceae	28216|Betaproteobacteria	NU	Type II secretion system	tadC	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
k59_772201_1	159087.Daro_3991	3.57e-33	119.0	COG4133@1|root,COG4133@2|Bacteria,1MZPC@1224|Proteobacteria,2VMGA@28216|Betaproteobacteria,2KW6J@206389|Rhodocyclales	206389|Rhodocyclales	O	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system	ccmA	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
k59_772201_2	159087.Daro_3992	1.05e-83	251.0	COG2386@1|root,COG2386@2|Bacteria,1NJB0@1224|Proteobacteria,2VNPU@28216|Betaproteobacteria,2KW4C@206389|Rhodocyclales	206389|Rhodocyclales	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmB	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
k59_832957_1	1537917.JU82_08525	1e-174	503.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,42MFA@68525|delta/epsilon subdivisions,2YMUE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
k59_540616_1	1163617.SCD_n00463	3.47e-97	309.0	COG2199@1|root,COG2202@1|root,COG3614@1|root,COG2199@2|Bacteria,COG2202@2|Bacteria,COG3614@2|Bacteria,1NWNJ@1224|Proteobacteria,2VN39@28216|Betaproteobacteria	28216|Betaproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GGDEF,PAS_3,PAS_9
k59_1184359_1	1304883.KI912532_gene855	1.08e-20	90.5	COG0304@1|root,COG0304@2|Bacteria,1MV30@1224|Proteobacteria,2VI0P@28216|Betaproteobacteria,2KVGF@206389|Rhodocyclales	206389|Rhodocyclales	IQ	Beta-ketoacyl synthase, C-terminal domain	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_1184359_2	1304883.KI912532_gene854	1.77e-46	150.0	COG0236@1|root,COG0236@2|Bacteria,1N6RU@1224|Proteobacteria,2VWKA@28216|Betaproteobacteria,2KWX4@206389|Rhodocyclales	206389|Rhodocyclales	IQ	Phosphopantetheine attachment site	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
k59_1184359_3	1304883.KI912532_gene853	3.27e-61	194.0	COG4648@1|root,COG4648@2|Bacteria,1RII0@1224|Proteobacteria,2VSMC@28216|Betaproteobacteria,2KX2J@206389|Rhodocyclales	206389|Rhodocyclales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1712600_1	387093.SUN_0537	8.5e-81	261.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,42MN5@68525|delta/epsilon subdivisions,2YN0Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	DUF294,GlnD_UR_UTase,HD,NTP_transf_2
k59_1009626_2	709032.Sulku_2416	1.29e-107	314.0	COG2908@1|root,COG2908@2|Bacteria,1MVKD@1224|Proteobacteria,42N20@68525|delta/epsilon subdivisions,2YN0N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
k59_1712610_1	1249480.B649_00045	1.37e-152	443.0	COG0784@1|root,COG5001@1|root,COG0784@2|Bacteria,COG5001@2|Bacteria,1MUNI@1224|Proteobacteria	1224|Proteobacteria	T	COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3369,EAL,GGDEF,Response_reg
k59_1301109_1	1328313.DS2_05225	8.3e-07	52.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQ86@1236|Gammaproteobacteria,465B4@72275|Alteromonadaceae	1236|Gammaproteobacteria	U	General secretion pathway protein F	gspF	GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
k59_1301109_2	265072.Mfla_1905	8.89e-69	230.0	COG1629@1|root,COG4771@2|Bacteria,1R4PY@1224|Proteobacteria,2VZJH@28216|Betaproteobacteria	28216|Betaproteobacteria	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_597737_1	640081.Dsui_3412	5.92e-45	158.0	COG1639@1|root,COG1639@2|Bacteria,1R4P9@1224|Proteobacteria,2VPPP@28216|Betaproteobacteria,2KVX9@206389|Rhodocyclales	206389|Rhodocyclales	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_712587_1	159087.Daro_0810	5.51e-118	347.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,2VHP5@28216|Betaproteobacteria,2KUBF@206389|Rhodocyclales	206389|Rhodocyclales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petB	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
k59_1712619_1	672.VV93_v1c24460	3.8e-09	59.3	COG0642@1|root,COG0745@1|root,COG2770@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG2770@2|Bacteria,1NRP8@1224|Proteobacteria,1T1Y4@1236|Gammaproteobacteria,1XTDR@135623|Vibrionales	135623|Vibrionales	T	Histidine kinase	chiS	-	-	ko:K19694	-	-	-	-	ko00000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_8,Response_reg
k59_1478414_1	1249480.B649_08170	2.03e-172	488.0	COG1546@1|root,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,42MQ4@68525|delta/epsilon subdivisions,2YMUS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA
k59_302316_2	272134.KB731324_gene6368	4.85e-18	80.1	COG1051@1|root,COG1051@2|Bacteria,1G513@1117|Cyanobacteria,1HAIP@1150|Oscillatoriales	1117|Cyanobacteria	F	Belongs to the Nudix hydrolase family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
k59_128809_1	159087.Daro_0217	0.0	1561.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,2VHUY@28216|Betaproteobacteria,2KUPX@206389|Rhodocyclales	206389|Rhodocyclales	E	glutamate synthase	gls1	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_420945_1	717773.Thicy_0169	3.45e-98	298.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,1RM7X@1236|Gammaproteobacteria,45ZZ1@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
k59_481240_1	485915.Dret_0609	2.35e-104	309.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,42M4P@68525|delta/epsilon subdivisions,2WIKX@28221|Deltaproteobacteria,2M9KK@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Polysaccharide biosynthesis protein	pseB	-	4.2.1.115	ko:K15894	ko00520,map00520	-	R09697	RC02609	ko00000,ko00001,ko01000	-	-	-	Polysacc_synt_2
k59_1831890_1	1249480.B649_00075	3.29e-31	116.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,42MWK@68525|delta/epsilon subdivisions,2YMIH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
k59_361628_1	1304883.KI912532_gene251	1.18e-127	374.0	COG0410@1|root,COG3945@1|root,COG0410@2|Bacteria,COG3945@2|Bacteria,1MVVC@1224|Proteobacteria,2VK1I@28216|Betaproteobacteria,2KZYP@206389|Rhodocyclales	206389|Rhodocyclales	E	Hemerythrin HHE cation binding domain	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,Hemerythrin
k59_245256_1	709032.Sulku_0409	9.51e-51	176.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1NQKX@1224|Proteobacteria,43CB3@68525|delta/epsilon subdivisions,2YTAN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG2200 FOG EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,sCache_2
k59_950787_1	709032.Sulku_1101	1.67e-130	380.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42QMQ@68525|delta/epsilon subdivisions,2YPR1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Protein of unknown function (DUF3365)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,GGDEF
k59_540703_1	29486.NJ56_04065	7.45e-62	192.0	COG1854@1|root,COG1854@2|Bacteria,1MWQF@1224|Proteobacteria,1RMDZ@1236|Gammaproteobacteria,41DBS@629|Yersinia	1236|Gammaproteobacteria	H	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)	luxS	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0007154,GO:0007267,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009116,GO:0009119,GO:0009372,GO:0009987,GO:0010699,GO:0016053,GO:0016829,GO:0016846,GO:0017144,GO:0019284,GO:0019752,GO:0023052,GO:0033353,GO:0034641,GO:0042278,GO:0043094,GO:0043102,GO:0043436,GO:0043768,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046128,GO:0046394,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0051704,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657	4.4.1.21	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	M00609	R01291	RC00069,RC01929	ko00000,ko00001,ko00002,ko01000	-	-	iECIAI39_1322.ECIAI39_2877,iPC815.YPO3300	LuxS
k59_67675_1	1304883.KI912532_gene654	1.62e-91	291.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,2VH4X@28216|Betaproteobacteria,2KUPP@206389|Rhodocyclales	206389|Rhodocyclales	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_1478449_1	709032.Sulku_1573	1.14e-28	110.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,42MYJ@68525|delta/epsilon subdivisions,2YN0I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS
k59_1478449_2	709032.Sulku_1572	5.54e-106	314.0	COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,42P4E@68525|delta/epsilon subdivisions,2YNAC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs	truD	-	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
k59_1127077_1	1249480.B649_08660	3.95e-88	272.0	COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,42QG6@68525|delta/epsilon subdivisions,2YMUP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	na -driven multidrug efflux	-	-	-	-	-	-	-	-	-	-	-	-	MatE
k59_597802_1	44251.PDUR_03235	1.03e-11	66.2	COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,4HAX6@91061|Bacilli,26TFE@186822|Paenibacillaceae	91061|Bacilli	P	Superoxide dismutase	sodF	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	DUF2935,Sod_Fe_C,Sod_Fe_N
k59_1422047_1	1537917.JU82_08750	2.24e-63	202.0	COG0656@1|root,COG0656@2|Bacteria,1PGB3@1224|Proteobacteria,42PPT@68525|delta/epsilon subdivisions,2YN3U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_1655527_1	1537917.JU82_01635	3.67e-112	326.0	COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,42N66@68525|delta/epsilon subdivisions,2YMY7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate	ate	-	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	ATE_C,ATE_N
k59_1655527_2	709032.Sulku_2265	8.46e-97	308.0	COG2199@1|root,COG3221@1|root,COG3437@1|root,COG2199@2|Bacteria,COG3221@2|Bacteria,COG3437@2|Bacteria,1RGCV@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD
k59_1479992_1	1249480.B649_00720	6.14e-38	139.0	COG1345@1|root,COG1345@2|Bacteria,1MUVP@1224|Proteobacteria,42MHW@68525|delta/epsilon subdivisions,2YNJG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	fliD	GO:0001539,GO:0005575,GO:0005576,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_IN,FliD_C,FliD_N
k59_1068870_1	1165841.SULAR_05588	2.66e-70	228.0	COG4942@1|root,COG4942@2|Bacteria,1QV6K@1224|Proteobacteria,42M9V@68525|delta/epsilon subdivisions,2YMS7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_1596766_1	709032.Sulku_1847	3.2e-59	188.0	28WAS@1|root,2ZIB8@2|Bacteria,1NBB7@1224|Proteobacteria,42P2G@68525|delta/epsilon subdivisions,2YNQ5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1011721_2	929558.SMGD1_0386	3.2e-14	75.9	COG0840@1|root,COG0840@2|Bacteria,1N5N4@1224|Proteobacteria,42RSG@68525|delta/epsilon subdivisions,2YRU6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
k59_482949_2	1123392.AQWL01000004_gene2694	4.31e-26	99.4	2ECSY@1|root,336QI@2|Bacteria,1N9AZ@1224|Proteobacteria,2VYWR@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1714059_2	1304883.KI912532_gene2501	1.95e-24	104.0	COG3501@1|root,COG4253@1|root,COG3501@2|Bacteria,COG4253@2|Bacteria,1MU7Q@1224|Proteobacteria,2VJSR@28216|Betaproteobacteria,2M01Y@206389|Rhodocyclales	206389|Rhodocyclales	S	Uncharacterized protein conserved in bacteria (DUF2345)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2345,Phage_GPD,T6SS_Vgr
k59_1540064_2	387093.SUN_2288	5.7e-29	110.0	COG1351@1|root,COG1351@2|Bacteria,1Q73I@1224|Proteobacteria,42N3X@68525|delta/epsilon subdivisions,2YMHF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
k59_1185759_1	1502770.JQMG01000001_gene1639	2.87e-161	460.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,2VI9P@28216|Betaproteobacteria,2KM29@206350|Nitrosomonadales	206350|Nitrosomonadales	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	-	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
k59_186773_1	1249480.B649_08735	2.77e-95	296.0	COG1450@1|root,COG1450@2|Bacteria,1MVNC@1224|Proteobacteria,43BJ2@68525|delta/epsilon subdivisions,2YN49@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Type II and III secretion system protein	ctsD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	STN,Secretin,Secretin_N_2
k59_1302225_1	1537917.JU82_11815	3.67e-39	135.0	COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,42R60@68525|delta/epsilon subdivisions,2YNZM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_1302225_2	1249480.B649_02560	1.13e-31	118.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,42N1R@68525|delta/epsilon subdivisions,2YMRZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_542599_1	1249480.B649_07175	7.51e-95	284.0	COG0697@1|root,COG0697@2|Bacteria,1MZXM@1224|Proteobacteria,42ME7@68525|delta/epsilon subdivisions,2YMBW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EG	membrane	-	-	-	ko:K15270	-	-	-	-	ko00000,ko02000	2.A.7.3.7	-	-	EamA
k59_659767_1	1537917.JU82_04585	1.51e-18	83.6	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,42M40@68525|delta/epsilon subdivisions,2YMGX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
k59_659767_2	709032.Sulku_0749	3.09e-144	410.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,42NEA@68525|delta/epsilon subdivisions,2YN5P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
k59_542602_1	1537917.JU82_08485	1.66e-154	459.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,42M70@68525|delta/epsilon subdivisions,2YMJM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_1302234_1	929558.SMGD1_1107	8.95e-83	271.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42NCZ@68525|delta/epsilon subdivisions,2YNKW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	czcA	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
k59_892440_1	1121035.AUCH01000005_gene160	2.35e-57	201.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KXVB@206389|Rhodocyclales	206389|Rhodocyclales	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4,PAS_9,dCache_1
k59_1128904_1	159087.Daro_2461	3.13e-72	221.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,2VH4T@28216|Betaproteobacteria,2KUMD@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the SUA5 family	yrdC	-	-	-	-	-	-	-	-	-	-	-	Sua5_yciO_yrdC
k59_1128904_2	159087.Daro_2462	1.02e-71	222.0	COG0613@1|root,COG0613@2|Bacteria,1MWIH@1224|Proteobacteria,2VHB2@28216|Betaproteobacteria,2KUXV@206389|Rhodocyclales	206389|Rhodocyclales	S	metal-dependent phosphoesterases (PHP family)	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
k59_303540_1	387093.SUN_1507	8.71e-30	110.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,42M8E@68525|delta/epsilon subdivisions,2YNXC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iIT341.HP0618	ADK
k59_303540_2	1165841.SULAR_04492	5.5e-236	660.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,42NC6@68525|delta/epsilon subdivisions,2YMJV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
k59_1361389_1	379731.PST_3851	2.53e-60	209.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,1RP9N@1236|Gammaproteobacteria,1Z1JU@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
k59_834730_2	1249480.B649_04765	1.61e-84	258.0	COG3190@1|root,COG3190@2|Bacteria,1Q1CX@1224|Proteobacteria,42PAU@68525|delta/epsilon subdivisions,2YP0B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1268017_1	159087.Daro_2786	1.32e-73	224.0	2E3CB@1|root,32YBM@2|Bacteria,1N6WD@1224|Proteobacteria,2VUUB@28216|Betaproteobacteria,2M031@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of unknown function (DUF4154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4154
k59_1268017_2	159087.Daro_2790	3.83e-05	44.7	COG3471@1|root,COG3471@2|Bacteria,1MZA2@1224|Proteobacteria,2VQW2@28216|Betaproteobacteria,2KWKU@206389|Rhodocyclales	206389|Rhodocyclales	S	secreted protein	-	-	-	-	-	-	-	-	-	-	-	-	SIMPL
k59_502163_1	1165841.SULAR_08030	1.08e-87	261.0	COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,42NV2@68525|delta/epsilon subdivisions,2YMFG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	ribosomal protein L3	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
k59_502163_2	1165841.SULAR_08035	4.45e-43	141.0	COG0051@1|root,COG0051@2|Bacteria,1RGWF@1224|Proteobacteria,42SE4@68525|delta/epsilon subdivisions,2YPG9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
k59_971794_1	1537917.JU82_06995	4.38e-21	90.5	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,42NCH@68525|delta/epsilon subdivisions,2YMW7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_1672438_2	1165841.SULAR_04267	1.63e-56	187.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,42N7A@68525|delta/epsilon subdivisions,2YMRE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	lytic murein transglycosylase	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
k59_1035102_1	1249480.B649_05980	2.19e-156	463.0	COG2319@1|root,COG2319@2|Bacteria,1Q4XR@1224|Proteobacteria,42PRP@68525|delta/epsilon subdivisions,2YMZB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	WD40
k59_1561095_4	511437.Lbuc_1535	6.17e-11	63.2	2EGZP@1|root,33ART@2|Bacteria,1VKPB@1239|Firmicutes,4HR69@91061|Bacilli,3F8RA@33958|Lactobacillaceae	91061|Bacilli	S	YopX protein	-	-	-	-	-	-	-	-	-	-	-	-	YopX
k59_502179_1	709032.Sulku_2260	2.88e-169	503.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42M0A@68525|delta/epsilon subdivisions,2YNJ1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	cznA	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
k59_502183_1	159087.Daro_3317	1.92e-100	296.0	COG3622@1|root,COG3622@2|Bacteria,1MV53@1224|Proteobacteria,2VJ19@28216|Betaproteobacteria,2KV78@206389|Rhodocyclales	206389|Rhodocyclales	G	to the hyi family	-	-	5.3.1.22,5.3.1.35	ko:K01816,ko:K22131	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
k59_1672449_1	1123228.AUIH01000004_gene1101	4.71e-49	174.0	COG1752@1|root,COG3772@1|root,COG1752@2|Bacteria,COG3772@2|Bacteria,1R4TX@1224|Proteobacteria,1RP66@1236|Gammaproteobacteria,1XQN9@135619|Oceanospirillales	135619|Oceanospirillales	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
k59_1613050_2	522772.Dacet_1135	9.93e-46	161.0	COG0635@1|root,COG0635@2|Bacteria,2GG8C@200930|Deferribacteres	200930|Deferribacteres	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k59_263211_1	159087.Daro_3703	1.78e-113	335.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,2VI9I@28216|Betaproteobacteria,2KU6U@206389|Rhodocyclales	206389|Rhodocyclales	P	Ammonium Transporter Family	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
k59_263211_2	159087.Daro_3704	1.5e-15	75.1	COG2821@1|root,COG2821@2|Bacteria,1MXD4@1224|Proteobacteria,2VHBF@28216|Betaproteobacteria,2KV14@206389|Rhodocyclales	206389|Rhodocyclales	M	Membrane-bound lytic murein transglycosylase	mltA	-	-	ko:K08304	-	-	-	-	ko00000,ko01000,ko01011	-	GH102	-	3D,MltA
k59_1148964_1	159087.Daro_2801	1.45e-26	107.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2VHCZ@28216|Betaproteobacteria,2KVY2@206389|Rhodocyclales	206389|Rhodocyclales	P	AcrB/AcrD/AcrF family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
k59_1148964_2	159087.Daro_2800	8.69e-43	151.0	COG0845@1|root,COG0845@2|Bacteria,1QN99@1224|Proteobacteria,2VQR3@28216|Betaproteobacteria,2KWDC@206389|Rhodocyclales	206389|Rhodocyclales	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
k59_619385_1	395494.Galf_0629	2.77e-60	199.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,2VITN@28216|Betaproteobacteria,44V0W@713636|Nitrosomonadales	28216|Betaproteobacteria	EGP	Sugar (and other) transporter	yajR	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
k59_83132_1	876044.IMCC3088_1522	1.17e-32	119.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,1RQ38@1236|Gammaproteobacteria,1J4KS@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0000028,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006417,GO:0006446,GO:0006450,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030371,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031554,GO:0031564,GO:0032268,GO:0032269,GO:0032270,GO:0032991,GO:0034248,GO:0034249,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045727,GO:0045903,GO:0045947,GO:0048027,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990145,GO:1990904,GO:2000112,GO:2000113,GO:2001141	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
k59_83132_2	1111732.AZOD01000006_gene45	4.24e-57	179.0	COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,1S3Q2@1236|Gammaproteobacteria,1X6JV@135614|Xanthomonadales	135614|Xanthomonadales	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
k59_564106_1	709032.Sulku_0657	1.56e-42	148.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,42NR0@68525|delta/epsilon subdivisions,2YMUN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
k59_564106_2	709032.Sulku_0658	2.5e-33	127.0	COG2199@1|root,COG2199@2|Bacteria,1QTZT@1224|Proteobacteria,43E8E@68525|delta/epsilon subdivisions,2YN2B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_1086678_1	1286093.C266_13644	1.46e-26	114.0	COG2801@1|root,COG2801@2|Bacteria,1MVXV@1224|Proteobacteria,2VIIE@28216|Betaproteobacteria,1K9Y1@119060|Burkholderiaceae	28216|Betaproteobacteria	L	MuA-transposase repressor protein CI, DNA-binding	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_Tnp_Mu_1,Mu-transpos_C,rve
k59_1789146_1	1304883.KI912532_gene2184	4.67e-96	287.0	COG1639@1|root,COG1639@2|Bacteria,1N7EN@1224|Proteobacteria,2VQMM@28216|Betaproteobacteria,2KXYM@206389|Rhodocyclales	206389|Rhodocyclales	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_793607_1	1537917.JU82_01045	3.91e-18	82.8	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,42NC6@68525|delta/epsilon subdivisions,2YMJV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
k59_908778_1	487316.BBNM01000002_gene1393	1.22e-07	59.7	COG0845@1|root,COG0845@2|Bacteria,1R866@1224|Proteobacteria,1SYE2@1236|Gammaproteobacteria,3NIFF@468|Moraxellaceae	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K18302	-	M00642	-	-	ko00000,ko00002,ko01504,ko02000	2.A.6.2,8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_1316732_1	709032.Sulku_2260	5.99e-181	533.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42M0A@68525|delta/epsilon subdivisions,2YNJ1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	cznA	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
k59_1731075_1	666681.M301_0880	1.31e-104	323.0	COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,2VH9I@28216|Betaproteobacteria,2KNHX@206350|Nitrosomonadales	206350|Nitrosomonadales	P	K+ potassium transporter	-	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
k59_564173_1	1449050.JNLE01000003_gene2164	2.17e-25	110.0	2DP3A@1|root,330CA@2|Bacteria,1UQ9I@1239|Firmicutes,251A7@186801|Clostridia,36SYC@31979|Clostridiaceae	186801|Clostridia	S	Glycine rich protein	-	-	-	-	-	-	-	-	-	-	-	-	Gly_rich
k59_149307_1	159087.Daro_2195	4.25e-27	100.0	COG3215@1|root,COG3215@2|Bacteria,1RGWZ@1224|Proteobacteria,2VT2B@28216|Betaproteobacteria,2KWKJ@206389|Rhodocyclales	206389|Rhodocyclales	NU	pilus assembly protein PilZ	pilZ	-	-	ko:K02676	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilZ
k59_149307_2	795666.MW7_1964	1.35e-11	68.6	COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,2VNED@28216|Betaproteobacteria,1K0JG@119060|Burkholderiaceae	28216|Betaproteobacteria	L	dna polymerase iii	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
k59_1379002_1	709032.Sulku_1995	1.6e-188	531.0	COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,42M87@68525|delta/epsilon subdivisions,2YNA4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	hemN	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
k59_1789201_1	1249480.B649_05800	5.19e-84	269.0	COG0659@1|root,COG0664@1|root,COG0659@2|Bacteria,COG0664@2|Bacteria,1MVWV@1224|Proteobacteria,42MMU@68525|delta/epsilon subdivisions,2YTMR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	STAS domain	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp,cNMP_binding
k59_851034_1	156889.Mmc1_2152	3.63e-40	148.0	COG1355@1|root,COG2078@1|root,COG1355@2|Bacteria,COG2078@2|Bacteria,1MXK5@1224|Proteobacteria,2U13I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
k59_83212_1	224324.aq_598	5.31e-18	81.3	COG3439@1|root,COG3439@2|Bacteria	2|Bacteria	D	Domain of unknown function DUF302	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Beta-lactamase,DUF302
k59_83212_2	709032.Sulku_1765	1.8e-53	167.0	COG5304@1|root,COG5304@2|Bacteria,1N269@1224|Proteobacteria,42VCY@68525|delta/epsilon subdivisions,2YQJ7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	CopG antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	CopG_antitoxin
k59_1086753_2	1249480.B649_10150	8.31e-93	271.0	COG3118@1|root,COG3118@2|Bacteria,1RHUA@1224|Proteobacteria,42S1N@68525|delta/epsilon subdivisions,2YPJI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Thioredoxin	-	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
k59_1088685_2	1217652.F954_00099	5.18e-07	57.4	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,3NJ45@468|Moraxellaceae	1236|Gammaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	5TM-5TMR_LYT,EAL,GAF_2,GGDEF,HAMP,MHYT,PAS,PAS_4,PAS_9,dCache_1
k59_1150976_1	709032.Sulku_2261	1.89e-93	284.0	COG0845@1|root,COG0845@2|Bacteria,1QMYR@1224|Proteobacteria,42WWX@68525|delta/epsilon subdivisions,2YR01@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	RND family efflux transporter, MFP subunit	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
k59_852627_1	443144.GM21_2898	2e-35	138.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,PAS,Response_reg
k59_1204028_1	159087.Daro_1603	3.74e-95	283.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,2VH6I@28216|Betaproteobacteria,2KUN1@206389|Rhodocyclales	206389|Rhodocyclales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
k59_1857026_2	709032.Sulku_0426	3.37e-126	365.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,42NCX@68525|delta/epsilon subdivisions,2YMK8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_1674303_1	1249480.B649_09180	5.26e-08	54.3	COG0795@1|root,COG0795@2|Bacteria,1PXEK@1224|Proteobacteria,42MVG@68525|delta/epsilon subdivisions,2YN6F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	permease	-	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_1674303_2	709032.Sulku_1922	1.33e-91	278.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,42KZH@68525|delta/epsilon subdivisions,2YMZM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
k59_852639_1	395494.Galf_0140	2.74e-86	261.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,2VH7N@28216|Betaproteobacteria,44VA6@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Endonuclease/Exonuclease/phosphatase family	xthA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
k59_852639_2	349521.HCH_00043	2.42e-09	57.4	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,1RMAH@1236|Gammaproteobacteria,1XHC0@135619|Oceanospirillales	135619|Oceanospirillales	E	Oligopeptidase	prlC	-	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
k59_1380982_1	666681.M301_1701	1.93e-51	186.0	COG2202@1|root,COG2203@1|root,COG5000@1|root,COG5001@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG5000@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KMBP@206350|Nitrosomonadales	206350|Nitrosomonadales	T	PFAM EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_9
k59_1088722_1	1232410.KI421418_gene2207	3.37e-72	227.0	COG0451@1|root,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,42MI8@68525|delta/epsilon subdivisions,2WJDT@28221|Deltaproteobacteria,43SIZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
k59_1381002_1	1249480.B649_01225	1.84e-111	326.0	COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,42MXH@68525|delta/epsilon subdivisions,2YMN3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	4-hydroxybenzoate	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
k59_379843_1	1165841.SULAR_09729	6.69e-21	87.0	2ETDC@1|root,33KX5@2|Bacteria,1P8PA@1224|Proteobacteria,42UDD@68525|delta/epsilon subdivisions,2YPXG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF420)	-	-	-	ko:K08976	-	-	-	-	ko00000	-	-	-	DUF420
k59_379843_2	1165841.SULAR_09734	6.48e-77	242.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42N0C@68525|delta/epsilon subdivisions,2YMDS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
k59_973897_1	1537917.JU82_11315	9.15e-63	204.0	COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,42P1M@68525|delta/epsilon subdivisions,2YN96@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Peptidase M48	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
k59_973897_2	1249480.B649_07810	1.56e-13	64.7	2AQJX@1|root,31FST@2|Bacteria,1QDI5@1224|Proteobacteria,432NI@68525|delta/epsilon subdivisions,2YSH6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1446155_2	709032.Sulku_2182	2.52e-66	214.0	COG0658@1|root,COG0658@2|Bacteria,1PY6P@1224|Proteobacteria,42NU2@68525|delta/epsilon subdivisions,2YME0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Competence protein	comE	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence
k59_621209_1	518766.Rmar_0343	1.14e-30	125.0	COG0840@1|root,COG3292@1|root,COG0840@2|Bacteria,COG3292@2|Bacteria,4NK8Q@976|Bacteroidetes	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GerE,HATPase_c,Reg_prop,SpoIIE,Y_Y_Y
k59_1270556_1	1249480.B649_04715	1.77e-100	298.0	COG0483@1|root,COG0483@2|Bacteria,1Q17W@1224|Proteobacteria,42T1U@68525|delta/epsilon subdivisions,2YPGV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Inositol monophosphatase	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
k59_318553_1	1537917.JU82_06335	1.37e-125	368.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,42UPM@68525|delta/epsilon subdivisions,2YRIE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL
k59_910683_2	1168067.JAGP01000001_gene1480	1.24e-45	160.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RNV0@1236|Gammaproteobacteria,4607Z@72273|Thiotrichales	72273|Thiotrichales	NU	type II secretion	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
k59_1446194_2	1297569.MESS2_870011	1.88e-44	160.0	COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,2TSGE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3,TPR_16,TPR_19,TPR_2,TPR_8
k59_910689_1	159087.Daro_2672	5.4e-123	374.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,2VHR1@28216|Betaproteobacteria,2KUJG@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k59_1497646_1	309803.CTN_0420	7.42e-13	65.9	COG0776@1|root,COG0776@2|Bacteria,2GDFH@200918|Thermotogae	200918|Thermotogae	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k59_566691_1	1304883.KI912532_gene1298	9.05e-20	81.3	COG0640@1|root,COG0640@2|Bacteria,1Q9DY@1224|Proteobacteria,2VVWF@28216|Betaproteobacteria,2KXM8@206389|Rhodocyclales	206389|Rhodocyclales	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
k59_566691_2	159087.Daro_3134	2.3e-60	198.0	COG2041@1|root,COG2041@2|Bacteria,1MX9E@1224|Proteobacteria,2VI1T@28216|Betaproteobacteria,2KVXK@206389|Rhodocyclales	206389|Rhodocyclales	S	Mo-co oxidoreductase dimerisation domain	-	-	-	ko:K17225	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	Mo-co_dimer,Oxidored_molyb
k59_1381086_1	1249480.B649_00980	3.01e-47	153.0	COG4875@1|root,COG4875@2|Bacteria,1RFS2@1224|Proteobacteria,43B6N@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Calcium/calmodulin dependent protein kinase II association domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
k59_1381086_2	1249480.B649_00990	2.64e-67	209.0	2BNSM@1|root,32HG6@2|Bacteria,1Q1E8@1224|Proteobacteria,42TDY@68525|delta/epsilon subdivisions,2YPGN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_207521_1	1537917.JU82_01665	1.89e-142	441.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2YMP9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5,RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_1088823_1	709032.Sulku_0325	1.48e-44	161.0	COG2198@1|root,COG2198@2|Bacteria,1PCKH@1224|Proteobacteria,42W9Z@68525|delta/epsilon subdivisions,2YQ6K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_151656_1	522306.CAP2UW1_0505	6.26e-72	228.0	COG0683@1|root,COG0683@2|Bacteria,1MWR8@1224|Proteobacteria,2VHH6@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Extracellular ligand-binding receptor	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
k59_1857169_1	387093.SUN_2041	1.42e-134	409.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,42N8X@68525|delta/epsilon subdivisions,2YMGZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_504411_1	1537917.JU82_07835	2.32e-103	325.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2YMQV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_1088827_1	123214.PERMA_1459	1.19e-25	109.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
k59_1088827_2	1158338.JNLJ01000001_gene950	1.3e-59	199.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
k59_1497669_1	159087.Daro_3936	7.64e-52	173.0	COG1273@1|root,COG1273@2|Bacteria,1QVC4@1224|Proteobacteria,2WGPK@28216|Betaproteobacteria,2KWNJ@206389|Rhodocyclales	206389|Rhodocyclales	S	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3426,zinc_ribbon_4,zinc_ribbon_5
k59_1497669_2	159087.Daro_3935	1.67e-50	167.0	COG0524@1|root,COG0524@2|Bacteria,1PDQE@1224|Proteobacteria,2VHMF@28216|Betaproteobacteria,2KUNE@206389|Rhodocyclales	206389|Rhodocyclales	G	COG0524 Sugar kinases, ribokinase family	pfkB	-	2.7.1.20	ko:K00856	ko00230,ko01100,map00230,map01100	-	R00185	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
k59_1857174_1	279714.FuraDRAFT_0058	6.84e-80	253.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,2VJPX@28216|Betaproteobacteria,2KPRT@206351|Neisseriales	206351|Neisseriales	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
k59_1857183_1	765910.MARPU_00480	9.27e-82	260.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,1RMB9@1236|Gammaproteobacteria,1WWMF@135613|Chromatiales	135613|Chromatiales	O	PFAM Magnesium chelatase, ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
k59_1791134_1	748247.AZKH_2372	9.6e-118	354.0	2C99Z@1|root,2Z9YV@2|Bacteria,1N0B7@1224|Proteobacteria,2W15Y@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3373)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3373
k59_566754_1	1537917.JU82_11570	1.19e-35	131.0	COG0168@1|root,COG0168@2|Bacteria,1N412@1224|Proteobacteria,42MBI@68525|delta/epsilon subdivisions,2YMWN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Potassium uptake protein	ktrB	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
k59_566754_2	161156.JQKW01000014_gene263	2.34e-10	62.0	COG3437@1|root,COG3437@2|Bacteria,2GHIJ@200940|Thermodesulfobacteria	2|Bacteria	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
k59_395727_1	1537917.JU82_01455	1.95e-88	271.0	COG2206@1|root,COG2206@2|Bacteria,1R53C@1224|Proteobacteria,42R7P@68525|delta/epsilon subdivisions,2YPRS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
k59_334794_1	1249480.B649_00290	0.000106	43.9	2DCNX@1|root,2ZESX@2|Bacteria,1QUV9@1224|Proteobacteria,43CMN@68525|delta/epsilon subdivisions,2YTEI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_583364_2	709032.Sulku_1461	1.48e-82	254.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,42M5K@68525|delta/epsilon subdivisions,2YMJ2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
k59_43586_1	1121035.AUCH01000008_gene963	1.58e-130	378.0	COG3876@1|root,COG3876@2|Bacteria,1MX3S@1224|Proteobacteria,2VMMF@28216|Betaproteobacteria,2KV9B@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
k59_1806674_1	1249480.B649_03325	3.09e-60	199.0	COG1807@1|root,COG1807@2|Bacteria,1Q901@1224|Proteobacteria,42MGX@68525|delta/epsilon subdivisions,2YNER@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
k59_813687_1	316067.Geob_3274	1.98e-63	204.0	COG2220@1|root,COG2220@2|Bacteria,1MUY6@1224|Proteobacteria,42Q5T@68525|delta/epsilon subdivisions,2WUTJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
k59_1055416_1	675815.VOA_002011	5.05e-50	180.0	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG5002@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,1SVEC@1236|Gammaproteobacteria,1Y33D@135623|Vibrionales	135623|Vibrionales	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_4,Response_reg
k59_281425_1	1230476.C207_05549	1.01e-19	90.5	COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,2TT84@28211|Alphaproteobacteria,3JTYR@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Belongs to the UPF0061 (SELO) family	MA20_28420	-	-	ko:K08997	-	-	-	-	ko00000	-	-	-	UPF0061
k59_281425_2	1537917.JU82_06820	9.92e-17	79.7	COG1315@1|root,COG1315@2|Bacteria,1R5P6@1224|Proteobacteria,42MAS@68525|delta/epsilon subdivisions,2YM7Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Flagellar Assembly Protein A	-	-	-	-	-	-	-	-	-	-	-	-	FapA
k59_168092_1	1304883.KI912532_gene1424	8.62e-53	174.0	COG1639@1|root,COG1639@2|Bacteria,1N7EN@1224|Proteobacteria,2VQMM@28216|Betaproteobacteria,2KXRB@206389|Rhodocyclales	206389|Rhodocyclales	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_168092_2	159087.Daro_0623	9.62e-83	246.0	COG0517@1|root,COG0517@2|Bacteria,1N0H3@1224|Proteobacteria,2VRN8@28216|Betaproteobacteria,2KX2P@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
k59_168092_3	159087.Daro_0624	6.94e-05	43.9	COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,2VQNZ@28216|Betaproteobacteria,2KUPA@206389|Rhodocyclales	206389|Rhodocyclales	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
k59_281433_2	1249480.B649_06075	1.38e-28	108.0	COG1999@1|root,COG1999@2|Bacteria,1Q4TG@1224|Proteobacteria,42ZV5@68525|delta/epsilon subdivisions,2YRVW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
k59_867102_1	159087.Daro_4037	3.14e-95	296.0	COG0642@1|root,COG0784@1|root,COG3850@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,COG3850@2|Bacteria,1NC9X@1224|Proteobacteria,2WGIN@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K11527,ko:K20973	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_9,Response_reg
k59_1873442_1	1442598.JABW01000008_gene776	1.92e-14	78.6	COG2199@1|root,COG3706@2|Bacteria,1N4XN@1224|Proteobacteria,43ANH@68525|delta/epsilon subdivisions,2YT2C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_1337345_1	358220.C380_05860	3.84e-18	81.3	COG0607@1|root,COG0640@1|root,COG0607@2|Bacteria,COG0640@2|Bacteria,1R71B@1224|Proteobacteria,2VI9S@28216|Betaproteobacteria,4ACDQ@80864|Comamonadaceae	28216|Betaproteobacteria	K	Bacterial regulatory protein, arsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5,Rhodanese
k59_1690373_1	709032.Sulku_2492	1.41e-117	346.0	COG2897@1|root,COG2897@2|Bacteria,1PI99@1224|Proteobacteria,42PX2@68525|delta/epsilon subdivisions,2YNFU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
k59_742379_2	1537917.JU82_06285	4.91e-43	141.0	COG1188@1|root,COG1188@2|Bacteria,1Q5X3@1224|Proteobacteria,42VKA@68525|delta/epsilon subdivisions,2YPZ3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	S4 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	S4
k59_993395_1	228399.appser1_16050	2.26e-23	93.6	COG2077@1|root,COG2077@2|Bacteria,1RAJ9@1224|Proteobacteria,1S263@1236|Gammaproteobacteria,1Y8HC@135625|Pasteurellales	135625|Pasteurellales	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	tpx	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	Redoxin
k59_993395_2	1101195.Meth11DRAFT_0885	2.27e-63	195.0	COG1694@1|root,COG1694@2|Bacteria,1N02D@1224|Proteobacteria,2VU39@28216|Betaproteobacteria,2KMX2@206350|Nitrosomonadales	206350|Nitrosomonadales	S	MazG-like family	-	-	-	-	-	-	-	-	-	-	-	-	MazG-like
k59_1806735_1	1249480.B649_01120	8.04e-98	296.0	COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,42N9J@68525|delta/epsilon subdivisions,2YMC3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Long-chain fatty acid transport protein	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k59_395835_1	272560.BPSL2091	8.58e-43	153.0	COG4102@1|root,COG4102@2|Bacteria,1MX4R@1224|Proteobacteria,2VH8S@28216|Betaproteobacteria,1K2D3@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Twin-arginine translocation pathway signal sequence	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501,TAT_signal
k59_395835_3	243090.RB11947	4.11e-05	48.1	COG3829@1|root,COG3829@2|Bacteria,2J4YU@203682|Planctomycetes	203682|Planctomycetes	K	Bacterial regulatory protein, Fis family	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_8,Sigma54_activat
k59_395835_4	401053.AciPR4_0954	1.91e-10	60.8	COG0138@1|root,COG0138@2|Bacteria,3Y2QI@57723|Acidobacteria,2JHSU@204432|Acidobacteriia	204432|Acidobacteriia	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
k59_1873483_1	1249480.B649_11755	2.38e-90	271.0	COG0388@1|root,COG0388@2|Bacteria,1PZZZ@1224|Proteobacteria,42REP@68525|delta/epsilon subdivisions,2YP77@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
k59_1168799_1	1537917.JU82_09765	1.29e-145	417.0	COG0191@1|root,COG0191@2|Bacteria,1MURX@1224|Proteobacteria,42MK7@68525|delta/epsilon subdivisions,2YMEQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	fructose-bisphosphate aldolase	fbaA	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
k59_1582132_2	497321.C664_17240	9.61e-30	114.0	COG0582@1|root,COG0582@2|Bacteria,1NWGS@1224|Proteobacteria,2VKWM@28216|Betaproteobacteria,2KV9M@206389|Rhodocyclales	206389|Rhodocyclales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
k59_1397533_1	292415.Tbd_2798	6.81e-84	256.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,2VJBW@28216|Betaproteobacteria,1KSC4@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
k59_1397533_2	395494.Galf_2935	5.29e-06	47.8	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,2VHQU@28216|Betaproteobacteria,44V6D@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_742410_1	1304883.KI912532_gene2321	4.88e-81	267.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,2VI7M@28216|Betaproteobacteria,2KVGD@206389|Rhodocyclales	206389|Rhodocyclales	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_583447_1	292415.Tbd_0710	1.69e-36	140.0	28KDQ@1|root,2ZA05@2|Bacteria,1QVCG@1224|Proteobacteria,2VTD9@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1168809_1	945713.IALB_3203	1.4e-24	107.0	COG1752@1|root,COG4775@1|root,COG1752@2|Bacteria,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	plpD	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Bac_surface_Ag,POTRA,Patatin
k59_930197_2	526218.Sterm_0528	3.5e-30	118.0	COG0745@1|root,COG0745@2|Bacteria,379Q8@32066|Fusobacteria	32066|Fusobacteria	K	Psort location Cytoplasmic, score 9.97	irlR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_1287336_1	1454004.AW11_03160	9.75e-37	134.0	COG3608@1|root,COG3608@2|Bacteria,1R784@1224|Proteobacteria,2VPWM@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA
k59_334904_1	1537917.JU82_06010	1.02e-75	229.0	COG2834@1|root,COG2834@2|Bacteria,1PQ15@1224|Proteobacteria,42WEH@68525|delta/epsilon subdivisions,2YPW1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
k59_334904_2	1249480.B649_06280	4.34e-91	275.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,42MJ0@68525|delta/epsilon subdivisions,2YMCZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Co Zn Cd efflux system component	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux,ZT_dimer
k59_1287343_1	709032.Sulku_0930	3.48e-88	261.0	COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,42QQ4@68525|delta/epsilon subdivisions,2YNX7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	iIT341.HP1016	CDP-OH_P_transf
k59_168215_1	159087.Daro_2848	2.21e-34	129.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,2VH1A@28216|Betaproteobacteria,2KVEX@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k59_1337421_1	709032.Sulku_0299	6.2e-58	192.0	2BQX9@1|root,32JUG@2|Bacteria,1Q2H0@1224|Proteobacteria,42VPF@68525|delta/epsilon subdivisions,2YQMK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1463353_1	391615.ABSJ01000055_gene1334	1.41e-102	310.0	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,1RQ8U@1236|Gammaproteobacteria,1J541@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	iEC042_1314.EC042_0998,iECNA114_1301.ECNA114_0940,iECSF_1327.ECSF_0829,iPC815.YPO1390	EPSP_synthase
k59_701692_1	159087.Daro_3393	5.21e-51	172.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,2VHZN@28216|Betaproteobacteria,2KUKJ@206389|Rhodocyclales	206389|Rhodocyclales	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
k59_585202_1	1537917.JU82_06800	5.82e-30	111.0	COG0621@1|root,COG0621@2|Bacteria,1MUCS@1224|Proteobacteria,42MN1@68525|delta/epsilon subdivisions,2YN0D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	MiaB-like tRNA modifying enzyme	yqeV	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,UPF0004
k59_585202_2	1537917.JU82_06795	2.06e-35	134.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42NK1@68525|delta/epsilon subdivisions,2YMHN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the AAA ATPase family	ftsH1	-	-	-	-	-	-	-	-	-	-	-	AAA,Peptidase_M41
k59_640057_1	1249480.B649_09460	2.98e-303	847.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,42KZI@68525|delta/epsilon subdivisions,2YR60@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Domain of unknown function (DUF3458_C) ARM repeats	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,Peptidase_M1
k59_1464870_1	1121377.KB906428_gene1164	1.86e-47	175.0	COG2199@1|root,COG2206@1|root,COG2206@2|Bacteria,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HAMP,HD,HD_5,Response_reg,TPR_12,TPR_7
k59_101610_1	1182590.BN5_01411	1.02e-111	349.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,1RP3T@1236|Gammaproteobacteria,1YEEV@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	G	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008986,GO:0009058,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0019318,GO:0019319,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0071704,GO:1901576	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	iEcE24377_1341.EcE24377A_1919,iYL1228.KPN_02160	PEP-utilizers,PEP-utilizers_C,PPDK_N
k59_521505_2	326298.Suden_0496	1.81e-17	77.0	COG1331@1|root,COG1331@2|Bacteria,1N55I@1224|Proteobacteria	1224|Proteobacteria	O	Peptidyl-prolyl cis-trans	-	-	-	-	-	-	-	-	-	-	-	-	FKBP_C,Thioredox_DsbH,Thioredoxin_7
k59_397957_1	387093.SUN_0089	6.96e-45	157.0	2BT8X@1|root,32NEA@2|Bacteria,1RGSX@1224|Proteobacteria,42S0P@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Predicted periplasmic lipoprotein (DUF2279)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2279
k59_815515_1	1150621.SMUL_2176	1.62e-45	168.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42NXX@68525|delta/epsilon subdivisions,2YP90@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	PFAM Methyl-accepting chemotaxis protein (MCP) signaling domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,MCPsignal
k59_1399066_1	1249480.B649_00680	1.93e-172	486.0	COG0673@1|root,COG0673@2|Bacteria,1QFVG@1224|Proteobacteria,42UT6@68525|delta/epsilon subdivisions,2YPS7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
k59_1583905_1	1165841.SULAR_04137	8.93e-22	88.2	COG0698@1|root,COG0698@2|Bacteria,1RHBF@1224|Proteobacteria,42SAN@68525|delta/epsilon subdivisions,2YPGI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
k59_1583905_2	1172190.M947_10425	8.54e-60	193.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,42N7M@68525|delta/epsilon subdivisions	1224|Proteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_101623_1	1304883.KI912532_gene389	3.23e-50	181.0	COG0642@1|root,COG4191@1|root,COG2205@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2WGMB@28216|Betaproteobacteria,2KYM8@206389|Rhodocyclales	206389|Rhodocyclales	T	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_7,Response_reg,dCache_1
k59_1399071_1	1132855.KB913035_gene224	3.55e-103	305.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,2VIG0@28216|Betaproteobacteria,2KM1A@206350|Nitrosomonadales	206350|Nitrosomonadales	K	Belongs to the ParB family	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
k59_995035_1	1165841.SULAR_00460	7.89e-60	188.0	COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,42QQ4@68525|delta/epsilon subdivisions,2YNX7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	iIT341.HP1016	CDP-OH_P_transf
k59_995035_2	387093.SUN_0806	4.42e-28	113.0	COG4773@1|root,COG4773@2|Bacteria	2|Bacteria	P	Receptor	-	-	-	-	-	-	-	-	-	-	-	-	Campylo_MOMP,OprD
k59_336477_1	709032.Sulku_0703	4.21e-92	289.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,42WJ0@68525|delta/epsilon subdivisions,2YQJR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	PFAM TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_45251_1	485916.Dtox_1224	1.54e-75	239.0	COG1206@1|root,COG1206@2|Bacteria,1TP67@1239|Firmicutes,24971@186801|Clostridia,260G4@186807|Peptococcaceae	186801|Clostridia	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	-	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
k59_521538_1	1537917.JU82_07015	9.51e-112	338.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,42M35@68525|delta/epsilon subdivisions,2YM7I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0354	DXP_synthase_N,Transket_pyr,Transketolase_C
k59_585281_1	709032.Sulku_2286	3.7e-59	189.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,42NPN@68525|delta/epsilon subdivisions,2YMV8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10	ko:K00795	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364	R01658,R02003	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
k59_585281_3	1537917.JU82_01780	4.74e-83	245.0	COG3411@1|root,COG3411@2|Bacteria,1N0XK@1224|Proteobacteria,42SE0@68525|delta/epsilon subdivisions,2YPJM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx
k59_703392_1	929558.SMGD1_1740	3.12e-44	163.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2YNJH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	His Kinase A (phospho-acceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
k59_1288940_1	395495.Lcho_3190	2e-10	67.0	COG1409@1|root,COG1409@2|Bacteria,1R4EJ@1224|Proteobacteria,2VN90@28216|Betaproteobacteria,1KNRS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_585295_1	1165841.SULAR_01618	1.87e-53	174.0	COG0745@1|root,COG0745@2|Bacteria,1R9AZ@1224|Proteobacteria,42NYS@68525|delta/epsilon subdivisions,2YNW2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	response regulator	dccR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_1399115_3	279714.FuraDRAFT_3761	3.26e-12	66.2	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,2VJTH@28216|Betaproteobacteria,2KPDI@206351|Neisseriales	206351|Neisseriales	M	Transporter, small conductance mechanosensitive ion channel MscS family protein	aefA	-	-	-	-	-	-	-	-	-	-	-	MS_channel
k59_585303_1	1249480.B649_06705	2.33e-11	60.8	2E4QW@1|root,32ZJG@2|Bacteria,1N8H1@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF3995)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3995
k59_585303_2	1249480.B649_06710	2.57e-94	278.0	COG1305@1|root,COG1305@2|Bacteria,1RJJ1@1224|Proteobacteria,43B4M@68525|delta/epsilon subdivisions,2YP25@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10,Transglut_core
k59_640157_1	1165841.SULAR_10564	1.13e-127	373.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,42MS9@68525|delta/epsilon subdivisions,2YMBY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
k59_703431_1	1537917.JU82_02090	1.82e-27	104.0	COG5456@1|root,COG5456@2|Bacteria,1Q27X@1224|Proteobacteria,42V4G@68525|delta/epsilon subdivisions,2YQE8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	FixH	-	-	-	-	-	-	-	-	-	-	-	-	FixH,YtkA
k59_703431_2	709032.Sulku_2344	2.73e-133	381.0	2AI9D@1|root,318Q0@2|Bacteria,1Q0R3@1224|Proteobacteria,42SDN@68525|delta/epsilon subdivisions,2YP0E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1875338_1	709032.Sulku_1317	7.78e-64	216.0	COG0835@1|root,COG0835@2|Bacteria,1QVCF@1224|Proteobacteria,42M0F@68525|delta/epsilon subdivisions,2YNAP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	PFAM CheW domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CheW,dCache_1
k59_1339093_1	1537917.JU82_02980	1.07e-114	342.0	COG0642@1|root,COG2205@2|Bacteria,1QUJ7@1224|Proteobacteria,43BJF@68525|delta/epsilon subdivisions,2YNM7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,sCache_like
k59_1288988_1	211586.SO_4657	9.37e-74	253.0	COG3614@1|root,COG3829@1|root,COG5001@1|root,COG3614@2|Bacteria,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2Q8QJ@267890|Shewanellaceae	1236|Gammaproteobacteria	T	SMART PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GGDEF,MASE1,PAS_9,Response_reg
k59_1288988_2	1122194.AUHU01000008_gene3295	3.18e-39	143.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,1RMA3@1236|Gammaproteobacteria,4644I@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
k59_1222508_1	387093.SUN_1950	9.77e-44	147.0	COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,42QX8@68525|delta/epsilon subdivisions,2YP1G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
k59_1875367_1	709032.Sulku_1051	2.26e-116	347.0	COG1944@1|root,COG1944@2|Bacteria,1MV7K@1224|Proteobacteria,42M8K@68525|delta/epsilon subdivisions,2YMZN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	YcaO cyclodehydratase, ATP-ad Mg2+-binding	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	YcaO
k59_1808476_2	1165841.SULAR_09049	1.58e-78	236.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,42MN8@68525|delta/epsilon subdivisions,2YPGX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Belongs to the Fur family	fur	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
k59_1808476_3	1165841.SULAR_09054	1.77e-26	107.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,42M90@68525|delta/epsilon subdivisions,2YMR5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k59_1231564_2	1132855.KB913035_gene662	2.15e-56	184.0	COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,2VJ27@28216|Betaproteobacteria,2KMMS@206350|Nitrosomonadales	206350|Nitrosomonadales	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
k59_291982_1	1537917.JU82_04710	1.86e-97	287.0	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,42MMC@68525|delta/epsilon subdivisions,2YMS8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the TtcA family	ttcA	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
k59_291982_2	1537917.JU82_04715	3.35e-56	179.0	2AYIJ@1|root,31QNB@2|Bacteria,1QN8F@1224|Proteobacteria,42T66@68525|delta/epsilon subdivisions,2YPFG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1348173_1	1537917.JU82_03795	5.97e-62	214.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2YMJS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,NIT,Response_reg
k59_1524455_1	929558.SMGD1_1374	2.52e-97	297.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,42PFM@68525|delta/epsilon subdivisions,2YMCN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_52167_1	593750.Metfor_2886	3.62e-11	67.8	COG0147@1|root,arCOG02014@2157|Archaea,2XU5J@28890|Euryarchaeota,2N9A9@224756|Methanomicrobia	224756|Methanomicrobia	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
k59_589604_2	76114.ebA1223	7.01e-15	75.1	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,2VR66@28216|Betaproteobacteria,2KWCH@206389|Rhodocyclales	206389|Rhodocyclales	U	Type II secretion system (T2SS), protein G	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
k59_1235392_2	1165841.SULAR_04873	1.29e-85	265.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,42M31@68525|delta/epsilon subdivisions,2YMGC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
k59_531480_1	580332.Slit_0877	6.19e-77	236.0	28I9W@1|root,2Z8CH@2|Bacteria,1QCN6@1224|Proteobacteria,2VM9W@28216|Betaproteobacteria	28216|Betaproteobacteria	S	SIR2-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
k59_354503_1	1249480.B649_01565	6.39e-131	380.0	COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,42QJ2@68525|delta/epsilon subdivisions,2YNBV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COGs COG3864 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
k59_354503_2	1249480.B649_01560	1.64e-147	421.0	COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,42QA8@68525|delta/epsilon subdivisions,2YNH6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_3
k59_765284_1	1121116.KB894787_gene87	4.99e-06	53.9	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2VHFJ@28216|Betaproteobacteria,4ACTE@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HCBP_related,HemolysinCabind
k59_531496_1	1150621.SMUL_0547	0.000131	43.9	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2YPJX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
k59_531496_2	709032.Sulku_0122	3.85e-35	132.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,42MIH@68525|delta/epsilon subdivisions,2YR84@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing EAL and modified HD-GYP domains	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
k59_1646229_1	326298.Suden_0553	2.16e-35	130.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,42N75@68525|delta/epsilon subdivisions,2YNFC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Metallophosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
k59_1646229_2	1165841.SULAR_03562	3.23e-41	137.0	COG1550@1|root,COG1550@2|Bacteria,1Q2MJ@1224|Proteobacteria,42VYB@68525|delta/epsilon subdivisions,2YQ9J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
k59_531514_2	1165841.SULAR_09754	9.15e-112	327.0	COG3751@1|root,COG3751@2|Bacteria,1Q4MK@1224|Proteobacteria,42ZFP@68525|delta/epsilon subdivisions,2YRNS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Prolyl 4-hydroxylase alpha subunit homologues.	-	-	-	ko:K07394	-	-	-	-	ko00000	-	-	-	2OG-FeII_Oxy_3
k59_1176983_1	105559.Nwat_0926	1.69e-38	143.0	COG1377@1|root,COG1377@2|Bacteria,1MUWI@1224|Proteobacteria,1RMHA@1236|Gammaproteobacteria,1WW1K@135613|Chromatiales	135613|Chromatiales	N	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhB	-	-	ko:K02401	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_2
k59_824651_1	1485544.JQKP01000005_gene383	4.86e-29	112.0	COG1261@1|root,COG1261@2|Bacteria,1N1SA@1224|Proteobacteria,2VR6V@28216|Betaproteobacteria,44VVV@713636|Nitrosomonadales	28216|Betaproteobacteria	N	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly	flgA	-	-	ko:K02386	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	ChapFlgA
k59_942060_1	1121459.AQXE01000001_gene2751	8.72e-113	336.0	28IR7@1|root,2Z8QR@2|Bacteria,1PBTP@1224|Proteobacteria,42Z7V@68525|delta/epsilon subdivisions,2WTZ3@28221|Deltaproteobacteria,2M8NA@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1823030_1	1172190.M947_00375	4.88e-97	303.0	COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,42MY0@68525|delta/epsilon subdivisions,2YMT1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
k59_3517_2	1524880.A0A076G7R3_9VIRU	4.81e-29	111.0	4QAUS@10239|Viruses	10239|Viruses	S	flavin adenine dinucleotide binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1235454_1	159087.Daro_2452	1.07e-108	337.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,2VK2H@28216|Betaproteobacteria,2KV2V@206389|Rhodocyclales	206389|Rhodocyclales	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N,IF2_assoc
k59_1235454_2	159087.Daro_2451	9.52e-56	175.0	COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,2VR43@28216|Betaproteobacteria,2KWPI@206389|Rhodocyclales	206389|Rhodocyclales	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
k59_295867_2	641491.DND132_2901	3.5e-34	129.0	COG3437@1|root,COG3437@2|Bacteria,1NDRJ@1224|Proteobacteria,42TDX@68525|delta/epsilon subdivisions,2WV2R@28221|Deltaproteobacteria,2M9V2@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
k59_354559_2	1537917.JU82_07210	3.15e-51	167.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,42PSG@68525|delta/epsilon subdivisions,2YMFJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
k59_1177009_1	1132855.KB913035_gene346	6e-76	239.0	COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,2VJ87@28216|Betaproteobacteria,2KKS6@206350|Nitrosomonadales	206350|Nitrosomonadales	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
k59_61380_1	709032.Sulku_0881	4.16e-81	262.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2YMAI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k59_1469796_1	709032.Sulku_1477	1.56e-91	278.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,42MV0@68525|delta/epsilon subdivisions,2YMKF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	ABC-type transport system involved in lipoprotein release permease component	lolC	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_531563_1	317025.Tcr_1142	3.75e-92	295.0	COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,1RNMC@1236|Gammaproteobacteria,45ZS8@72273|Thiotrichales	72273|Thiotrichales	C	Belongs to the aconitase IPM isomerase family	-	-	4.2.1.3,4.2.1.99	ko:K01682	ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173	R01324,R01325,R01900,R04425	RC00497,RC00498,RC00618,RC01153	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_2_N,Aconitase_B_N
k59_1411401_1	1537917.JU82_06765	1.17e-114	335.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,42NBS@68525|delta/epsilon subdivisions,2YMPP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	riboflavin biosynthesis protein	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
k59_295882_1	1537917.JU82_07735	8.58e-62	208.0	COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,42NB2@68525|delta/epsilon subdivisions,2YMVN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
k59_295882_2	1249480.B649_03765	3.1e-30	109.0	COG1959@1|root,COG1959@2|Bacteria,1MZ1C@1224|Proteobacteria,42SJM@68525|delta/epsilon subdivisions,2YPJG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
k59_824698_1	264462.Bd2010	1.37e-20	90.5	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,42MUZ@68525|delta/epsilon subdivisions,2MSU8@213481|Bdellovibrionales,2WJT6@28221|Deltaproteobacteria	213481|Bdellovibrionales	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_824698_2	1123400.KB904791_gene63	1.28e-25	110.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,45ZY0@72273|Thiotrichales	72273|Thiotrichales	EH	Anthranilate synthase component I	-	-	2.6.1.85,4.1.3.27	ko:K01657,ko:K01665	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
k59_1823090_2	709032.Sulku_0881	2.22e-139	417.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2YMAI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k59_649089_1	290398.Csal_3286	3.27e-53	181.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,1RP4V@1236|Gammaproteobacteria,1XHRG@135619|Oceanospirillales	135619|Oceanospirillales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_1000716_1	159087.Daro_1979	6.23e-88	272.0	COG0642@1|root,COG5000@1|root,COG2205@2|Bacteria,COG5000@2|Bacteria,1MUAK@1224|Proteobacteria,2VJ6W@28216|Betaproteobacteria,2KUEB@206389|Rhodocyclales	206389|Rhodocyclales	T	Periplasmic domain of Sensor histidine kinase RisS	-	-	2.7.13.3	ko:K07638	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,RisS_PPD
k59_1000716_2	159087.Daro_1978	1.05e-09	58.5	COG1639@1|root,COG1639@2|Bacteria,1RASR@1224|Proteobacteria,2VR0D@28216|Betaproteobacteria,2KWNY@206389|Rhodocyclales	206389|Rhodocyclales	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_1411419_1	1537917.JU82_06605	6.71e-41	146.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42N0C@68525|delta/epsilon subdivisions,2YMDS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
k59_1411419_2	1120946.AUBF01000006_gene219	0.000357	44.7	COG1683@1|root,COG1683@2|Bacteria,2IJAV@201174|Actinobacteria,4D5YR@85005|Actinomycetales	201174|Actinobacteria	S	Protein of unknown function (DUF523)	-	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	DUF523,PNP_UDP_1
k59_1823098_1	1249480.B649_00105	7.5e-14	69.7	COG0226@1|root,COG0226@2|Bacteria,1MUAZ@1224|Proteobacteria,42NM3@68525|delta/epsilon subdivisions,2YMMK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
k59_1118003_1	1537917.JU82_02225	2.44e-123	360.0	2C76X@1|root,2ZM1W@2|Bacteria,1P5JD@1224|Proteobacteria,42P9T@68525|delta/epsilon subdivisions,2YMRC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_237552_2	709032.Sulku_1751	4.85e-172	485.0	COG3608@1|root,COG3608@2|Bacteria,1RG3Y@1224|Proteobacteria,42R0N@68525|delta/epsilon subdivisions,2YNXP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Desuccinylase aspartoacylase	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
k59_295914_2	1123393.KB891316_gene1791	1.05e-08	55.5	COG3193@1|root,COG3193@2|Bacteria,1RJ3X@1224|Proteobacteria,2WFMV@28216|Betaproteobacteria,1KSR6@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Haem-degrading	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
k59_1823139_1	709032.Sulku_1387	6e-122	363.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,42PUI@68525|delta/epsilon subdivisions,2YN3E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	PFAM TrkA-N domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2,TrkA_N
k59_354641_2	159087.Daro_3210	5.88e-44	147.0	COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,2VITY@28216|Betaproteobacteria,2KV31@206389|Rhodocyclales	206389|Rhodocyclales	U	MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k59_354643_1	1304883.KI912532_gene449	2.51e-90	281.0	COG0745@1|root,COG2208@1|root,COG0745@2|Bacteria,COG2208@2|Bacteria,1N4K5@1224|Proteobacteria,2VKGP@28216|Betaproteobacteria,2KVU6@206389|Rhodocyclales	206389|Rhodocyclales	T	Sigma factor PP2C-like phosphatases	-	-	-	ko:K20977	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	PAS,Response_reg,SpoIIE
k59_354647_1	545694.TREPR_3871	5.92e-06	49.3	COG1708@1|root,COG1708@2|Bacteria,2J96F@203691|Spirochaetes	203691|Spirochaetes	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
k59_472638_1	234267.Acid_1546	1.71e-12	72.4	COG4251@1|root,COG5000@1|root,COG4251@2|Bacteria,COG5000@2|Bacteria,3Y3VG@57723|Acidobacteria	57723|Acidobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,CHASE8,HATPase_c,HisKA,PAS_4
k59_942201_1	640081.Dsui_0771	1.56e-28	108.0	COG1961@1|root,COG1961@2|Bacteria,1R3XB@1224|Proteobacteria,2VI00@28216|Betaproteobacteria,2KWEY@206389|Rhodocyclales	206389|Rhodocyclales	L	Helix-turn-helix domain of resolvase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_7,Resolvase
k59_649189_1	159087.Daro_0131	2.89e-46	154.0	2F8Y9@1|root,341A3@2|Bacteria,1NZBI@1224|Proteobacteria,2W3I6@28216|Betaproteobacteria,2KYYW@206389|Rhodocyclales	206389|Rhodocyclales	S	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
k59_649189_2	1304883.KI912532_gene656	6.72e-81	249.0	COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,2VHU9@28216|Betaproteobacteria,2KVER@206389|Rhodocyclales	206389|Rhodocyclales	E	Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine	metX	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
k59_1646370_1	159087.Daro_3689	1.17e-109	325.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,2VHNC@28216|Betaproteobacteria,2KV1D@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
k59_649190_1	1502770.JQMG01000001_gene491	5.17e-171	487.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,2VH4P@28216|Betaproteobacteria,2KM2C@206350|Nitrosomonadales	206350|Nitrosomonadales	T	PFAM PhoH family protein	-	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
k59_649191_1	1380600.AUYN01000001_gene2269	3.56e-14	79.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,1HXKJ@117743|Flavobacteriia	976|Bacteroidetes	DM	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,GNVR,Wzz
k59_354660_1	1236976.JCM16418_3437	1.18e-34	140.0	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG5002@2|Bacteria,1UII2@1239|Firmicutes,4HGW5@91061|Bacilli,26QEY@186822|Paenibacillaceae	91061|Bacilli	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
k59_589796_2	1249480.B649_00355	1.76e-57	188.0	COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,42NI1@68525|delta/epsilon subdivisions,2YMHQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
k59_1588039_2	1165841.SULAR_06348	1.82e-06	49.3	COG4968@1|root,COG4968@2|Bacteria,1QUIY@1224|Proteobacteria,42S53@68525|delta/epsilon subdivisions,2YPC3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Prepilin-type N-terminal cleavage methylation domain	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
k59_3718_1	159087.Daro_0731	1.77e-67	208.0	COG1871@1|root,COG1871@2|Bacteria,1RDDB@1224|Proteobacteria,2VJ1T@28216|Betaproteobacteria,2KUYV@206389|Rhodocyclales	206389|Rhodocyclales	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	-	-	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
k59_1529614_1	1249480.B649_03950	3.23e-67	209.0	COG3672@1|root,COG3672@2|Bacteria,1RDQS@1224|Proteobacteria,42QWJ@68525|delta/epsilon subdivisions,2YNVX@29547|Epsilonproteobacteria	68525|delta/epsilon subdivisions	S	Bacterial transglutaminase-like cysteine proteinase BTLCP	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C93
k59_1529614_2	1249480.B649_03945	2.1e-21	92.8	COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,42MP9@68525|delta/epsilon subdivisions	1224|Proteobacteria	V	ABC transporter, transmembrane region	rtxB	-	-	ko:K12541	ko02010,map02010	M00330	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.109.3,3.A.1.109.4	-	-	ABC_membrane,ABC_tran,Peptidase_C39
k59_237623_1	159087.Daro_3723	1.92e-52	168.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,2VMQQ@28216|Betaproteobacteria,2KW7T@206389|Rhodocyclales	206389|Rhodocyclales	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
k59_237623_2	159087.Daro_3722	3.94e-40	137.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,2VRD3@28216|Betaproteobacteria,2KWFM@206389|Rhodocyclales	206389|Rhodocyclales	L	methyltransferase	-	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
k59_1529616_1	1132855.KB913035_gene2168	1.54e-94	301.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KNJ1@206350|Nitrosomonadales	206350|Nitrosomonadales	T	PFAM EAL domain protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_9
k59_354674_1	225937.HP15_1239	4.8e-50	181.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,464EF@72275|Alteromonadaceae	1236|Gammaproteobacteria	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	GO:0000166,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016884,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	iECH74115_1262.ECH74115_3792,iECO111_1330.ECO111_3283,iECSP_1301.ECSP_3501,iECs_1301.ECs3423,iG2583_1286.G2583_3088,iJN746.PP_1037,ic_1306.c3080	AIRS_C,GATase_5
k59_1532737_1	1537917.JU82_08265	2.51e-123	360.0	COG0475@1|root,COG0475@2|Bacteria,1QTSD@1224|Proteobacteria,43BNR@68525|delta/epsilon subdivisions,2YT9V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	glutathione-regulated potassium-efflux system protein	kefB	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
k59_1179642_1	637390.AFOH01000061_gene1109	1.47e-40	144.0	COG1451@1|root,COG1451@2|Bacteria,1R8SX@1224|Proteobacteria,1RNX7@1236|Gammaproteobacteria,2NCVV@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
k59_180586_2	563192.HMPREF0179_03457	2.27e-74	243.0	COG0749@1|root,COG0749@2|Bacteria,1P27P@1224|Proteobacteria,42YUP@68525|delta/epsilon subdivisions,2WTS1@28221|Deltaproteobacteria,2MAPB@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	DNA polymerase A domain	-	-	-	-	-	-	-	-	-	-	-	-	DNA_pol_A
k59_122984_1	709032.Sulku_1036	7.53e-132	387.0	COG1032@1|root,COG1032@2|Bacteria,1Q5NG@1224|Proteobacteria,42N2D@68525|delta/epsilon subdivisions,2YNAR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4080,Radical_SAM
k59_240132_1	387092.NIS_0548	2.62e-66	206.0	COG3829@1|root,COG3829@2|Bacteria,1RH32@1224|Proteobacteria,42QQM@68525|delta/epsilon subdivisions,2YNZA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	signal transduction sensor histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PAS,PAS_3
k59_240132_2	387093.SUN_0597	1.01e-57	186.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,42N3Z@68525|delta/epsilon subdivisions,2YMT4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
k59_6956_2	709032.Sulku_2158	1.53e-20	82.8	COG1145@1|root,COG1145@2|Bacteria,1QUJB@1224|Proteobacteria,42TSI@68525|delta/epsilon subdivisions,2YPU2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Ferredoxin	fdxA	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
k59_945182_1	1165841.SULAR_10534	4.39e-76	248.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,42MEI@68525|delta/epsilon subdivisions,2YN3Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Asparagine synthase, glutamine-hydrolyzing	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_1239148_1	497965.Cyan7822_5247	1.94e-17	87.8	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,3KGDE@43988|Cyanothece	1117|Cyanobacteria	T	PAS fold-4 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_475478_1	107635.AZUO01000001_gene1067	3.71e-15	75.9	COG1416@1|root,COG1416@2|Bacteria,1RKXJ@1224|Proteobacteria,2UA5Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	DsrE/DsrF-like family	-	-	-	ko:K09004	-	-	-	-	ko00000	-	-	-	DrsE
k59_1355200_1	1304883.KI912532_gene2479	7.47e-172	494.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,2VHM5@28216|Betaproteobacteria,2KVPJ@206389|Rhodocyclales	206389|Rhodocyclales	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
k59_1003962_1	709032.Sulku_0319	8.79e-58	202.0	COG1361@1|root,COG1361@2|Bacteria,1QVSF@1224|Proteobacteria,42QQ6@68525|delta/epsilon subdivisions,2YTBA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_240162_1	1249480.B649_00245	6.66e-69	226.0	COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,42NGP@68525|delta/epsilon subdivisions,2YN81@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Flagellar hook protein flgE	flgE	GO:0005575,GO:0005623,GO:0009288,GO:0009425,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flagellin_IN,Flg_bb_rod,Flg_bbr_C
k59_945205_1	1249480.B649_09655	8.99e-126	359.0	COG1309@1|root,COG1309@2|Bacteria,1RG05@1224|Proteobacteria,42RA4@68525|delta/epsilon subdivisions,2YNVU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_1766502_1	1165841.SULAR_06553	4.39e-92	278.0	COG3660@1|root,COG3660@2|Bacteria,1RC47@1224|Proteobacteria,42R32@68525|delta/epsilon subdivisions,2YNVT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Mitochondrial fission ELM1	-	-	-	ko:K07276	-	-	-	-	ko00000	-	-	-	Mito_fiss_Elm1
k59_534960_1	709032.Sulku_2442	1.78e-76	238.0	COG0577@1|root,COG0577@2|Bacteria,1QT4V@1224|Proteobacteria,42P7K@68525|delta/epsilon subdivisions,2YNGD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	ABC transporter permease	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
k59_534960_2	1537917.JU82_02230	6.61e-69	211.0	2E8DE@1|root,332RW@2|Bacteria,1N96Q@1224|Proteobacteria,42W98@68525|delta/epsilon subdivisions,2YQFB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1826441_1	709032.Sulku_1739	1.51e-70	236.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2YRKW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0474 Cation transport ATPase	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
k59_708918_1	1304883.KI912532_gene1675	3.14e-151	429.0	COG0121@1|root,COG0121@2|Bacteria,1MU1J@1224|Proteobacteria,2VJP1@28216|Betaproteobacteria,2KVVH@206389|Rhodocyclales	206389|Rhodocyclales	S	glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase_4
k59_1649128_1	1123514.KB905899_gene838	8.41e-82	264.0	COG2199@1|root,COG3706@2|Bacteria,1MWHH@1224|Proteobacteria,1RRU7@1236|Gammaproteobacteria,460V7@72273|Thiotrichales	72273|Thiotrichales	T	7TMR-DISM extracellular 2	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,GGDEF
k59_1532815_1	1304883.KI912532_gene1514	2.36e-113	326.0	COG0494@1|root,COG0494@2|Bacteria,1RDGJ@1224|Proteobacteria,2VIDX@28216|Betaproteobacteria,2KU7I@206389|Rhodocyclales	206389|Rhodocyclales	L	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage	nudH	-	-	ko:K08311	ko03018,map03018	-	R10816	RC00002	ko00000,ko00001,ko01000,ko03019	-	-	-	NUDIX
k59_298177_1	1123514.KB905899_gene838	3.41e-113	347.0	COG2199@1|root,COG3706@2|Bacteria,1MWHH@1224|Proteobacteria,1RRU7@1236|Gammaproteobacteria,460V7@72273|Thiotrichales	72273|Thiotrichales	T	7TMR-DISM extracellular 2	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,GGDEF
k59_1472978_1	1249480.B649_04250	1.31e-96	299.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,42MVQ@68525|delta/epsilon subdivisions,2YMEZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CO	Thiol disulfide interchange protein	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin,Thioredoxin_2,Thioredoxin_7
k59_1707831_1	159087.Daro_2974	1.8e-210	588.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,2VHBR@28216|Betaproteobacteria,2KV2X@206389|Rhodocyclales	206389|Rhodocyclales	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
k59_1609572_2	748247.AZKH_0021	4.33e-29	113.0	COG0687@1|root,COG0687@2|Bacteria,1MU0I@1224|Proteobacteria,2VICQ@28216|Betaproteobacteria,2KUCH@206389|Rhodocyclales	206389|Rhodocyclales	E	Bacterial extracellular solute-binding protein	-	-	-	ko:K02055	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	SBP_bac_8
k59_614789_1	1122185.N792_08575	5.69e-43	152.0	COG0526@1|root,COG0526@2|Bacteria,1RAW3@1224|Proteobacteria,1S43V@1236|Gammaproteobacteria,1XCBM@135614|Xanthomonadales	135614|Xanthomonadales	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	LGT,Redoxin
k59_614789_2	159087.Daro_1445	5.08e-77	237.0	COG2197@1|root,COG2199@1|root,COG2197@2|Bacteria,COG3706@2|Bacteria,1MVNV@1224|Proteobacteria,2VH9E@28216|Betaproteobacteria,2KVF5@206389|Rhodocyclales	206389|Rhodocyclales	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_723418_1	1121448.DGI_2419	1.59e-35	129.0	COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,42SN2@68525|delta/epsilon subdivisions,2WPT4@28221|Deltaproteobacteria,2MBH6@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family	kdsC	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
k59_435139_2	745310.G432_10660	8.74e-75	244.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,2TSW4@28211|Alphaproteobacteria,2K1BG@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
k59_1083175_1	1165841.SULAR_00135	3.26e-137	409.0	COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,42MY0@68525|delta/epsilon subdivisions,2YMT1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
k59_614796_1	1249480.B649_00280	5.21e-38	133.0	2AK2A@1|root,31ARZ@2|Bacteria,1Q60U@1224|Proteobacteria,43274@68525|delta/epsilon subdivisions,2YSGH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_200870_2	709032.Sulku_0234	3.98e-106	320.0	2C99Z@1|root,2Z9YV@2|Bacteria,1N0B7@1224|Proteobacteria,42P3M@68525|delta/epsilon subdivisions,2YMWY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF3373)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3373
k59_1850201_1	1537917.JU82_02455	1.42e-83	268.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42P9M@68525|delta/epsilon subdivisions,2YNH7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CZB,HAMP,MCPsignal,dCache_3
k59_905342_1	387093.SUN_0443	7.39e-103	306.0	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,42MRS@68525|delta/epsilon subdivisions,2YNCB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0330	IlvC,IlvN
k59_848128_1	1537917.JU82_03135	2.51e-67	218.0	COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,42MPN@68525|delta/epsilon subdivisions,2YMHV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Flagellar basal body protein	flgE	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bb_rod,Flg_bbr_C
k59_966972_1	1304883.KI912532_gene601	9.35e-104	306.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,2VICZ@28216|Betaproteobacteria,2KVIC@206389|Rhodocyclales	206389|Rhodocyclales	M	Lipid A biosynthesis acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
k59_200914_1	342113.DM82_4547	1.52e-49	177.0	COG1387@1|root,COG1387@2|Bacteria,1MYXV@1224|Proteobacteria,2VJIQ@28216|Betaproteobacteria,1K4RW@119060|Burkholderiaceae	28216|Betaproteobacteria	L	DNA polymerase	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
k59_676471_1	1165841.SULAR_07013	8.26e-55	177.0	COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,42SQE@68525|delta/epsilon subdivisions,2YPHI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	GO:0003674,GO:0003824,GO:0004141,GO:0016874,GO:0016879,GO:0016882	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
k59_676471_2	1408428.JNJP01000033_gene1548	4.51e-15	70.5	COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,42TN3@68525|delta/epsilon subdivisions,2WQ23@28221|Deltaproteobacteria,2MCM5@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
k59_614858_1	204773.HEAR1468	1.72e-69	224.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2VJME@28216|Betaproteobacteria,473G9@75682|Oxalobacteraceae	28216|Betaproteobacteria	G	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k59_1312948_1	1537917.JU82_11295	1.23e-56	176.0	COG2214@1|root,COG2214@2|Bacteria,1QXNV@1224|Proteobacteria,42X9T@68525|delta/epsilon subdivisions	1224|Proteobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
k59_1144494_1	1165841.SULAR_04167	1.21e-157	454.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,42M2G@68525|delta/epsilon subdivisions,2YMS0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
k59_1144494_2	123214.PERMA_1769	3.45e-09	57.4	COG2703@1|root,COG2703@2|Bacteria,2G48F@200783|Aquificae	200783|Aquificae	P	TIGRFAM hemerythrin-like metal-binding protein	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
k59_1439106_1	159087.Daro_3415	7.25e-72	233.0	COG0642@1|root,COG0642@2|Bacteria,1R49A@1224|Proteobacteria,2VKU5@28216|Betaproteobacteria,2KUK9@206389|Rhodocyclales	206389|Rhodocyclales	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_967005_1	709032.Sulku_1976	5.96e-17	74.7	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42UQ6@68525|delta/epsilon subdivisions,2YQ4Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	PFAM PAS fold-3 domain protein	-	-	-	ko:K03776	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	PAS_3
k59_1609655_1	666681.M301_0058	1.53e-49	161.0	COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,2VR5S@28216|Betaproteobacteria,2KMQS@206350|Nitrosomonadales	206350|Nitrosomonadales	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	-	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
k59_1609655_2	666681.M301_0057	9.22e-35	129.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,2VISB@28216|Betaproteobacteria,2KM9C@206350|Nitrosomonadales	206350|Nitrosomonadales	I	PFAM Carbamoyl-phosphate synthase L chain	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
k59_905381_1	1123518.ARWI01000001_gene1424	1.82e-19	83.6	COG0745@1|root,COG0745@2|Bacteria,1RDNP@1224|Proteobacteria,1S47I@1236|Gammaproteobacteria,460U7@72273|Thiotrichales	72273|Thiotrichales	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
k59_905381_2	317025.Tcr_0747	4.45e-95	285.0	COG1191@1|root,COG1191@2|Bacteria,1MWEU@1224|Proteobacteria,1RMKJ@1236|Gammaproteobacteria,460EM@72273|Thiotrichales	72273|Thiotrichales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes	fliA	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_1439129_1	1123355.JHYO01000003_gene2888	2.9e-20	97.1	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2TWEB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
k59_1492756_1	1249480.B649_07510	2.16e-87	281.0	COG5001@1|root,COG5001@2|Bacteria,1R4H0@1224|Proteobacteria,43CII@68525|delta/epsilon subdivisions,2YTD5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_559579_1	1249480.B649_01125	1.02e-89	277.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2YTAQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
k59_80083_1	1249480.B649_04280	7.07e-102	307.0	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,42MJ9@68525|delta/epsilon subdivisions,2YNG4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
k59_1083245_1	1249480.B649_05580	2.28e-156	443.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,42MEE@68525|delta/epsilon subdivisions,2YN8Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
k59_559580_1	1249480.B649_03275	3.43e-133	394.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,42KZ7@68525|delta/epsilon subdivisions,2YMB1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iIT341.HP1532	GATase_6,SIS
k59_1439155_1	709032.Sulku_1740	6.1e-89	266.0	COG2063@1|root,COG2063@2|Bacteria,1RDEY@1224|Proteobacteria,42MJW@68525|delta/epsilon subdivisions,2YN3R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgH	-	-	ko:K02393	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgH
k59_1727386_1	1122599.AUGR01000013_gene732	2.34e-09	59.3	COG0642@1|root,COG0642@2|Bacteria,1NXDJ@1224|Proteobacteria,1T1YN@1236|Gammaproteobacteria,1XRYP@135619|Oceanospirillales	135619|Oceanospirillales	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
k59_1727386_2	1565314.OA34_06750	4.58e-26	111.0	COG0840@1|root,COG0840@2|Bacteria,1R5W9@1224|Proteobacteria,42PPM@68525|delta/epsilon subdivisions,2YN9B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	methyl-accepting chemotaxis protein	tlpD	-	-	-	-	-	-	-	-	-	-	-	CZB,MCPsignal
k59_200993_1	1304883.KI912532_gene3259	7.58e-117	347.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,2KVA7@206389|Rhodocyclales	206389|Rhodocyclales	L	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k59_1198533_1	709032.Sulku_2179	1.16e-60	194.0	COG2863@1|root,COG2863@2|Bacteria,1Q4WC@1224|Proteobacteria,42NFN@68525|delta/epsilon subdivisions,2YMWE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Plasminogen-binding protein pgbA N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PGBA_N
k59_614974_1	709032.Sulku_2240	4.04e-129	384.0	COG1450@1|root,COG1450@2|Bacteria,1QXWT@1224|Proteobacteria,43CKP@68525|delta/epsilon subdivisions,2YN73@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	COG1450 Type II secretory pathway component PulD	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N_2
k59_967107_1	1249480.B649_08330	4.31e-13	67.0	COG0340@1|root,COG0340@2|Bacteria,1Q1NZ@1224|Proteobacteria,42RQM@68525|delta/epsilon subdivisions,2YP5C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	biotin acetyl-CoA-carboxylase ligase	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_LplA_LipB
k59_967107_2	1537917.JU82_04595	5.97e-160	454.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,42M3E@68525|delta/epsilon subdivisions,2YMQZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
k59_1609722_2	1000565.METUNv1_01766	2.08e-112	342.0	COG5362@1|root,COG5362@2|Bacteria,1N1KT@1224|Proteobacteria,2VJWB@28216|Betaproteobacteria,2KYMG@206389|Rhodocyclales	206389|Rhodocyclales	S	TIGRFAM Phage	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1439232_1	159087.Daro_0732	4.39e-75	236.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,2VI13@28216|Betaproteobacteria,2KUJP@206389|Rhodocyclales	206389|Rhodocyclales	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
k59_1375634_1	709032.Sulku_0325	5.04e-56	194.0	COG2198@1|root,COG2198@2|Bacteria,1PCKH@1224|Proteobacteria,42W9Z@68525|delta/epsilon subdivisions,2YQ6K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_314637_2	1198232.CYCME_0707	6.8e-138	404.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,1RMEJ@1236|Gammaproteobacteria,460BS@72273|Thiotrichales	72273|Thiotrichales	M	Peptidoglycan polymerase that is essential for cell wall elongation	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
k59_80180_1	709032.Sulku_2246	1.19e-120	353.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,42ME1@68525|delta/epsilon subdivisions,2YMI9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
k59_146216_1	525897.Dbac_2258	9.11e-34	118.0	COG2026@1|root,COG2026@2|Bacteria,1MZ76@1224|Proteobacteria,42TVA@68525|delta/epsilon subdivisions,2WRTD@28221|Deltaproteobacteria,2MCXR@213115|Desulfovibrionales	28221|Deltaproteobacteria	DJ	TIGRFAM Addiction module toxin, RelE StbE	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
k59_146216_2	525897.Dbac_2257	3.44e-30	108.0	COG2161@1|root,COG2161@2|Bacteria,1N6YR@1224|Proteobacteria,42TJ9@68525|delta/epsilon subdivisions,2WRWA@28221|Deltaproteobacteria,2MCPH@213115|Desulfovibrionales	28221|Deltaproteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	ko:K18923	-	-	-	-	ko00000,ko02048	-	-	-	PhdYeFM_antitox
k59_788915_1	1249480.B649_07410	3.84e-87	270.0	COG1538@1|root,COG1538@2|Bacteria,1MYX2@1224|Proteobacteria,42MHZ@68525|delta/epsilon subdivisions,2YNGC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	Outer membrane efflux protein	-	-	-	ko:K12543	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	1.B.17,3.A.1.109.4	-	-	OEP,OmpA,TSP_3
k59_967213_1	1123367.C666_00210	1.82e-12	68.6	COG1269@1|root,COG1269@2|Bacteria,1MXZG@1224|Proteobacteria,2VMAH@28216|Betaproteobacteria,2KUGS@206389|Rhodocyclales	206389|Rhodocyclales	C	Protein of unknown function (DUF3485)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3485,Exosortase_EpsH
k59_967213_2	987059.RBXJA2T_05328	2.92e-17	82.8	COG0438@1|root,COG0438@2|Bacteria,1MVIM@1224|Proteobacteria,2VJT7@28216|Betaproteobacteria,1KMBZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Glycosyl transferases group 1	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
k59_1313076_1	1249480.B649_09275	9.52e-90	270.0	COG1234@1|root,COG1234@2|Bacteria	2|Bacteria	L	tRNA 3'-trailer cleavage	-	-	3.1.26.11,3.1.4.17	ko:K00784,ko:K01120	ko00230,ko03013,map00230,map03013	-	R00191,R01234	RC00296	ko00000,ko00001,ko01000,ko03016	-	-	-	GAF,HD_5,Lactamase_B_2,PDEase_II
k59_1609788_1	395494.Galf_0799	2.13e-63	209.0	COG1808@1|root,COG1808@2|Bacteria,1NMS3@1224|Proteobacteria,2VJXX@28216|Betaproteobacteria,44WEB@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Domain of unknown function (DUF389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
k59_1263792_1	709032.Sulku_1416	6.56e-124	360.0	COG0770@1|root,COG0770@2|Bacteria,1Q5GZ@1224|Proteobacteria,42RQ8@68525|delta/epsilon subdivisions,2YP4M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity	-	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	-
k59_559760_1	1123517.JOMR01000001_gene213	1.84e-76	249.0	COG1262@1|root,COG2227@1|root,COG1262@2|Bacteria,COG2227@2|Bacteria,1MUNC@1224|Proteobacteria,1RQI4@1236|Gammaproteobacteria,45ZXU@72273|Thiotrichales	72273|Thiotrichales	NT	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase,Methyltransf_31
k59_676702_1	709032.Sulku_1905	5.2e-57	189.0	COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,42N4Y@68525|delta/epsilon subdivisions,2YNCE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase,Methyltransf_11,Methyltransf_31
k59_1850471_1	358220.C380_01980	2.12e-128	369.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,2VHR5@28216|Betaproteobacteria,4AARU@80864|Comamonadaceae	28216|Betaproteobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
k59_435400_1	441620.Mpop_0564	1.86e-26	114.0	COG1216@1|root,COG1216@2|Bacteria,1MX5Z@1224|Proteobacteria,2U0IP@28211|Alphaproteobacteria,1JRY7@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
k59_435400_2	263358.VAB18032_10750	1.43e-05	50.1	COG1216@1|root,COG1216@2|Bacteria,2I2M3@201174|Actinobacteria,4DB36@85008|Micromonosporales	201174|Actinobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_1375717_1	273121.WS2199	3.47e-21	94.4	COG2604@1|root,COG2604@2|Bacteria,1R4P0@1224|Proteobacteria,42NB8@68525|delta/epsilon subdivisions,2YMMI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	hmm pf01973	pseE	-	-	-	-	-	-	-	-	-	-	-	MAF_flag10
k59_1556905_1	535289.Dtpsy_1461	2.36e-92	302.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2VHCZ@28216|Betaproteobacteria,4AB5C@80864|Comamonadaceae	28216|Betaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07239,ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1,2.A.6.1.2	-	-	ACR_tran
k59_1030492_1	159087.Daro_2984	1.75e-40	144.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,2VIGA@28216|Betaproteobacteria,2KUKY@206389|Rhodocyclales	206389|Rhodocyclales	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
k59_1030492_2	159087.Daro_2983	1.48e-66	207.0	COG2976@1|root,COG2976@2|Bacteria,1N117@1224|Proteobacteria,2VSHE@28216|Betaproteobacteria,2KWT1@206389|Rhodocyclales	206389|Rhodocyclales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TPR_21
k59_1439376_1	709032.Sulku_0003	1.05e-109	337.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,42M7M@68525|delta/epsilon subdivisions,2YMUW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_201213_1	640081.Dsui_0116	3.56e-54	172.0	COG0599@1|root,COG0599@2|Bacteria,1MZ80@1224|Proteobacteria,2VU9A@28216|Betaproteobacteria,2KWSH@206389|Rhodocyclales	206389|Rhodocyclales	O	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
k59_201213_2	1247726.MIM_c34110	1.82e-12	64.7	COG1765@1|root,COG1765@2|Bacteria,1MWPR@1224|Proteobacteria,2VM4K@28216|Betaproteobacteria,3T514@506|Alcaligenaceae	28216|Betaproteobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
k59_967316_1	326298.Suden_0248	3.88e-48	175.0	COG0715@1|root,COG0834@1|root,COG4191@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43CE0@68525|delta/epsilon subdivisions,2YTBK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	NMT1,SBP_bac_3
k59_615197_1	292415.Tbd_2714	7.62e-76	244.0	COG1492@1|root,COG1492@2|Bacteria,1MUFY@1224|Proteobacteria,2VII5@28216|Betaproteobacteria,1KRXE@119069|Hydrogenophilales	119069|Hydrogenophilales	H	AAA domain	-	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_3
k59_1439397_1	709032.Sulku_1757	2.35e-97	312.0	COG1305@1|root,COG4196@1|root,COG1305@2|Bacteria,COG4196@2|Bacteria,1MVAG@1224|Proteobacteria,42P26@68525|delta/epsilon subdivisions,2YN89@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Putative amidoligase enzyme (DUF2126)	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,DUF2126,Transglut_core
k59_1556947_1	1537917.JU82_10810	2.82e-138	402.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,42NGG@68525|delta/epsilon subdivisions,2YN35@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Nucleotidyltransferase DNA polymerase involved in DNA repair	dinP	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
k59_905603_1	640081.Dsui_0076	1.38e-27	107.0	COG1670@1|root,COG1670@2|Bacteria,1PSUT@1224|Proteobacteria,2WA5E@28216|Betaproteobacteria,2KZJA@206389|Rhodocyclales	206389|Rhodocyclales	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
k59_905603_2	1249480.B649_00665	4.17e-60	195.0	COG0037@1|root,COG0037@2|Bacteria,1NKHX@1224|Proteobacteria,42Q26@68525|delta/epsilon subdivisions,2YT3T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	TIGRFAM N-acetyl sugar amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1727613_1	525903.Taci_0269	6.58e-90	272.0	COG0549@1|root,COG0549@2|Bacteria,3TAEJ@508458|Synergistetes	508458|Synergistetes	E	Belongs to the carbamate kinase family	-	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
k59_1263926_1	395493.BegalDRAFT_3105	1.36e-39	152.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,1RM9X@1236|Gammaproteobacteria,45ZTR@72273|Thiotrichales	72273|Thiotrichales	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N,IF2_assoc
k59_723679_1	709032.Sulku_1821	8.51e-83	247.0	2ENFG@1|root,33G2V@2|Bacteria,1NPDC@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
k59_1850621_1	1249480.B649_06355	1.32e-109	326.0	COG0477@1|root,COG2814@2|Bacteria,1MXPM@1224|Proteobacteria,42NXE@68525|delta/epsilon subdivisions,2YTHH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EGP	LacY proton/sugar symporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_1492999_1	1158345.JNLL01000001_gene8	1e-40	138.0	COG2905@1|root,COG2905@2|Bacteria	2|Bacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
k59_1492999_2	1249480.B649_04315	2.86e-38	142.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,42MW3@68525|delta/epsilon subdivisions,2YMT6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
k59_263588_2	159087.Daro_3000	1.84e-100	306.0	COG1807@1|root,COG1807@2|Bacteria,1PUE3@1224|Proteobacteria,2VHPU@28216|Betaproteobacteria,2KUEG@206389|Rhodocyclales	206389|Rhodocyclales	M	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
k59_439341_1	1249480.B649_09790	3.17e-129	374.0	COG0642@1|root,COG0642@2|Bacteria,1QZ1Z@1224|Proteobacteria,42SN7@68525|delta/epsilon subdivisions,2YPK7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
k59_1444187_1	360106.CFF8240_1584	1.45e-52	186.0	COG3914@1|root,COG3914@2|Bacteria,1RM6B@1224|Proteobacteria,42P52@68525|delta/epsilon subdivisions,2YNTE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	O-linked N-acetylglucosamine transferase SPINDLY family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_378369_1	1121403.AUCV01000010_gene1406	3.04e-44	156.0	COG0392@1|root,COG0392@2|Bacteria,1MVZ8@1224|Proteobacteria,42WVD@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
k59_83566_1	709032.Sulku_1056	1.99e-44	149.0	COG0175@1|root,COG0175@2|Bacteria,1MXUR@1224|Proteobacteria,42PUJ@68525|delta/epsilon subdivisions,2YN9G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EH	Reduction of activated sulfate into sulfite	cysH	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
k59_83566_2	709032.Sulku_1057	3.95e-79	242.0	COG0175@1|root,COG0175@2|Bacteria,1MUCZ@1224|Proteobacteria,42NYE@68525|delta/epsilon subdivisions,2YN2H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase	cysD	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
k59_83572_1	563040.Saut_0840	8.67e-16	70.1	2AMTT@1|root,31CQB@2|Bacteria,1Q9FV@1224|Proteobacteria,432P1@68525|delta/epsilon subdivisions,2YSWX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_83572_2	929558.SMGD1_1412	8.33e-68	223.0	COG2010@1|root,COG3391@1|root,COG2010@2|Bacteria,COG3391@2|Bacteria,1N3PN@1224|Proteobacteria,42Q19@68525|delta/epsilon subdivisions,2YNSV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	nitrite reductase	-	-	1.7.2.1,1.7.99.1	ko:K15864	ko00910,ko01120,map00910,map01120	M00529	R00143,R00783,R00785	RC00086,RC02797	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_D1,Cytochrome_CBB3
k59_1035748_1	709032.Sulku_0344	3.33e-170	479.0	COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,42QA8@68525|delta/epsilon subdivisions,2YNH6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_3
k59_1789548_1	1304883.KI912532_gene1889	2.64e-14	67.0	COG4256@1|root,COG4256@2|Bacteria,1Q0N9@1224|Proteobacteria,2W5HJ@28216|Betaproteobacteria,2KZM0@206389|Rhodocyclales	206389|Rhodocyclales	P	Hemin uptake protein hemP	-	-	-	-	-	-	-	-	-	-	-	-	hemP
k59_26492_1	1249480.B649_10570	1.02e-53	177.0	COG4968@1|root,COG4968@2|Bacteria,1R1K8@1224|Proteobacteria,43DAN@68525|delta/epsilon subdivisions,2YTHS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
k59_924479_1	709032.Sulku_1505	2.76e-70	230.0	COG2199@1|root,COG3706@2|Bacteria,1R1K2@1224|Proteobacteria,42YWW@68525|delta/epsilon subdivisions,2YR1I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Double sensory domain of two-component sensor kinase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_3
k59_924479_2	56780.SYN_02218	8.08e-18	84.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2WIU0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
k59_330406_2	1304883.KI912532_gene2354	1.76e-143	421.0	COG2766@1|root,COG2766@2|Bacteria,1MVW7@1224|Proteobacteria,2VI2M@28216|Betaproteobacteria,2KVKE@206389|Rhodocyclales	206389|Rhodocyclales	T	PrkA family serine protein kinase	prkA	-	-	ko:K07180	-	-	-	-	ko00000	-	-	-	AAA_PrkA,PrkA
k59_738410_1	709032.Sulku_0404	3e-26	106.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42NHE@68525|delta/epsilon subdivisions,2YMQ8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
k59_738410_2	1537917.JU82_06875	4.13e-104	303.0	COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,43BC4@68525|delta/epsilon subdivisions,2YMGN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
k59_1628900_1	709032.Sulku_1608	1.23e-178	511.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1R5RS@1224|Proteobacteria,42M3K@68525|delta/epsilon subdivisions,2YN6E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	PFAM biotin lipoyl attachment domain-containing protein	pycB	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
k59_634204_2	1249480.B649_02470	3.24e-56	185.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,42PCH@68525|delta/epsilon subdivisions,2YN62@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	3-deoxy-d-manno-octulosonic-acid transferase	kdtA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	iIT341.HP0957	Glycos_transf_N
k59_1686025_1	1249480.B649_05035	1.67e-94	280.0	COG1521@1|root,COG1521@2|Bacteria,1PZXA@1224|Proteobacteria,42RA8@68525|delta/epsilon subdivisions,2YP14@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
k59_578649_1	709032.Sulku_0841	6.72e-37	135.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42NVA@68525|delta/epsilon subdivisions,2YMYW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
k59_578649_2	1537917.JU82_11380	3.39e-29	114.0	COG1538@1|root,COG1538@2|Bacteria,1QNYC@1224|Proteobacteria,42TDW@68525|delta/epsilon subdivisions,2YPR5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_1628909_1	1249480.B649_02190	1.15e-22	91.3	COG2010@1|root,COG2010@2|Bacteria,1PBN0@1224|Proteobacteria,42RGJ@68525|delta/epsilon subdivisions,2YPBP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome c	-	-	-	ko:K17223	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C
k59_1628909_2	1249480.B649_02185	2.9e-76	238.0	COG5002@1|root,COG5002@2|Bacteria,1QUJ9@1224|Proteobacteria,42MEB@68525|delta/epsilon subdivisions,2YMXI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_863123_1	1249480.B649_02625	3.71e-28	105.0	2E6EV@1|root,3312A@2|Bacteria,1N8Q0@1224|Proteobacteria,42WW1@68525|delta/epsilon subdivisions,2YRZ8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PgaD-like protein	-	-	-	ko:K11937	ko02026,map02026	-	-	-	ko00000,ko00001	-	-	-	PgaD
k59_863123_2	1249480.B649_02630	7.01e-198	556.0	COG1215@1|root,COG1215@2|Bacteria,1MXG7@1224|Proteobacteria,42Q7W@68525|delta/epsilon subdivisions,2YQ1A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Glycosyl transferase family 21	-	-	-	ko:K11936	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.1.1.2,4.D.1.1.3	GT2	-	Glyco_tranf_2_3
k59_809243_2	317025.Tcr_0600	2.37e-19	84.3	COG3793@1|root,COG3793@2|Bacteria,1NWK1@1224|Proteobacteria,1SPRH@1236|Gammaproteobacteria,462G7@72273|Thiotrichales	72273|Thiotrichales	P	PFAM Mo-dependent nitrogenase	-	-	-	-	-	-	-	-	-	-	-	-	TerB
k59_394910_2	159087.Daro_3942	2.5e-144	417.0	COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,2VIX5@28216|Betaproteobacteria,2KUZ4@206389|Rhodocyclales	206389|Rhodocyclales	M	Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate	mpl	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_929207_1	387093.SUN_1956	9.41e-117	348.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MSP@68525|delta/epsilon subdivisions,2YMGI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
k59_394917_1	709032.Sulku_1867	2.48e-142	414.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,42MV4@68525|delta/epsilon subdivisions,2YN13@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
k59_334222_1	1249480.B649_00020	1.6e-86	268.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1RGCV@1224|Proteobacteria,42M47@68525|delta/epsilon subdivisions,2YMRS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	(EAL) domain protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_1336739_1	709032.Sulku_1270	2.78e-103	316.0	COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,42NYT@68525|delta/epsilon subdivisions,2YNMV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
k59_637865_1	1249480.B649_04315	2.45e-150	446.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,42MW3@68525|delta/epsilon subdivisions,2YMT6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
k59_1336749_1	1123518.ARWI01000001_gene1345	6.13e-27	109.0	COG0715@1|root,COG0715@2|Bacteria,1NV0U@1224|Proteobacteria,1SNZC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	-
k59_1336749_2	317025.Tcr_2024	1.29e-50	183.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE8,EAL,GGDEF,PAS_4
k59_1750903_1	395494.Galf_1842	2.97e-82	248.0	COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,2VKZV@28216|Betaproteobacteria,44VNR@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Inhibitor of apoptosis-promoting Bax1	-	-	-	ko:K19416	-	M00742	-	-	ko00000,ko00002,ko02000	1.A.14.2.1	-	-	Bax1-I
k59_1750903_2	1500894.JQNN01000001_gene3511	3.25e-43	156.0	COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,2VH6A@28216|Betaproteobacteria,472U8@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	Likely ribonuclease with RNase H fold.	tex	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
k59_1220530_1	1537917.JU82_11565	4.6e-99	293.0	COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,42R60@68525|delta/epsilon subdivisions,2YNZM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_1104468_1	761193.Runsl_1386	6.29e-67	218.0	COG2234@1|root,COG2234@2|Bacteria,4NE66@976|Bacteroidetes,47MBT@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
k59_1396929_1	1304883.KI912532_gene27	7e-77	233.0	COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,2VIU9@28216|Betaproteobacteria,2KW2K@206389|Rhodocyclales	206389|Rhodocyclales	J	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit	ftsJ	-	2.1.1.166	ko:K02427	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
k59_1396929_2	159087.Daro_0944	1.24e-59	199.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,2VHEV@28216|Betaproteobacteria,2KU76@206389|Rhodocyclales	206389|Rhodocyclales	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_1514115_1	1537917.JU82_11215	1.17e-78	241.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,42M84@68525|delta/epsilon subdivisions,2YN32@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
k59_1514115_2	1537917.JU82_11220	9.52e-18	80.5	COG1651@1|root,COG1651@2|Bacteria,1RFRJ@1224|Proteobacteria,42SPD@68525|delta/epsilon subdivisions,2YP88@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
k59_456632_1	1304883.KI912532_gene700	1.16e-26	107.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,2VHBZ@28216|Betaproteobacteria,2KUYH@206389|Rhodocyclales	206389|Rhodocyclales	M	Catalyzes cross-linking of the peptidoglycan cell wall	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
k59_456632_2	1304883.KI912532_gene699	9.11e-116	332.0	COG2891@1|root,COG2891@2|Bacteria,1RBNF@1224|Proteobacteria,2VQQ3@28216|Betaproteobacteria,2KW9X@206389|Rhodocyclales	206389|Rhodocyclales	M	shape-determining protein	mreD	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
k59_395092_1	713587.THITH_07385	4.52e-50	176.0	COG0457@1|root,COG0457@2|Bacteria,1QXGV@1224|Proteobacteria	1224|Proteobacteria	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
k59_1750972_1	1123326.JFBL01000007_gene625	4.07e-71	232.0	COG0304@1|root,COG0304@2|Bacteria,1N91E@1224|Proteobacteria,42PU1@68525|delta/epsilon subdivisions,2YNTQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_1750972_2	177439.DP1838	1.59e-25	104.0	COG4990@1|root,COG4990@2|Bacteria,1MVC4@1224|Proteobacteria,42QF6@68525|delta/epsilon subdivisions,2WM99@28221|Deltaproteobacteria,2MKVS@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Butirosin biosynthesis protein H, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BtrH_N,DUF4872
k59_1581602_1	998674.ATTE01000001_gene2939	2.26e-88	278.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,1RZYP@1236|Gammaproteobacteria,461UJ@72273|Thiotrichales	72273|Thiotrichales	P	Domain of unknown function DUF21	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
k59_456651_1	1537917.JU82_10575	2.34e-31	119.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,42P35@68525|delta/epsilon subdivisions,2YN2K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	iIT341.HP0867	LpxB
k59_456651_2	1537917.JU82_10570	3.24e-45	150.0	2AHYJ@1|root,318BT@2|Bacteria,1Q04R@1224|Proteobacteria,42RKI@68525|delta/epsilon subdivisions,2YPAQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_701031_1	709032.Sulku_1874	5.58e-85	265.0	COG3746@1|root,COG3746@2|Bacteria,1MY3M@1224|Proteobacteria,42NVN@68525|delta/epsilon subdivisions,2YMH8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_167568_1	1123514.KB905899_gene1439	1.62e-103	313.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,45ZZ6@72273|Thiotrichales	72273|Thiotrichales	T	PFAM response regulator receiver	-	-	-	ko:K10943	ko02020,ko05111,map02020,map05111	M00515	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_395106_1	1249480.B649_05400	5.53e-205	579.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,42MEQ@68525|delta/epsilon subdivisions,2YMGS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	COG0058 Glucan phosphorylase	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
k59_701043_2	56780.SYN_00867	2.29e-56	187.0	COG1215@1|root,COG1215@2|Bacteria,1MWH9@1224|Proteobacteria,42PX0@68525|delta/epsilon subdivisions,2WJUG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	-	-	2.4.1.266	ko:K13693	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	-
k59_1632851_1	159087.Daro_1750	3.32e-65	218.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,2VHTX@28216|Betaproteobacteria,2KV13@206389|Rhodocyclales	206389|Rhodocyclales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_1632851_2	1454004.AW11_01612	9.35e-11	61.6	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,2VHBW@28216|Betaproteobacteria,1KQ8B@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	M	Peptidase family M50	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
k59_334366_1	1249480.B649_09240	4.04e-08	53.1	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,42NMR@68525|delta/epsilon subdivisions,2YN8M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k59_334366_2	709032.Sulku_1934	5.87e-92	273.0	COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,42SQE@68525|delta/epsilon subdivisions,2YPHI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	GO:0003674,GO:0003824,GO:0004141,GO:0016874,GO:0016879,GO:0016882	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
k59_1336880_1	1537917.JU82_09925	1.54e-127	369.0	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,42MRS@68525|delta/epsilon subdivisions,2YNCB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0330	IlvC,IlvN
k59_1168190_1	698761.RTCIAT899_CH17300	1.88e-29	119.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,2TRZU@28211|Alphaproteobacteria,4B9AH@82115|Rhizobiaceae	28211|Alphaproteobacteria	CH	hydroxylase	ubiH	GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016491,GO:0019168,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901576,GO:1901661,GO:1901663	-	ko:K03185	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04989,R08773	RC02670	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
k59_638017_1	40149.OMERI01G20770.1	5.83e-17	80.9	COG0007@1|root,KOG1527@2759|Eukaryota,37KMV@33090|Viridiplantae,3GC67@35493|Streptophyta,3KMHV@4447|Liliopsida,3I5KA@38820|Poales	35493|Streptophyta	H	Belongs to the precorrin methyltransferase family	-	-	2.1.1.107	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03194	RC00003,RC00871	ko00000,ko00001,ko00002,ko01000	-	-	-	TP_methylase
k59_638017_2	76114.ebA888	9.25e-07	51.2	COG2010@1|root,COG2010@2|Bacteria,1N3PN@1224|Proteobacteria,2VHSF@28216|Betaproteobacteria,2KVT2@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome D1 heme domain	nirS	-	1.7.2.1,1.7.99.1	ko:K15864	ko00910,ko01120,map00910,map01120	M00529	R00143,R00783,R00785	RC00086,RC02797	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_D1,Cytochrome_CBB3
k59_1689916_1	1263831.F543_3810	5.17e-70	231.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,1RNS1@1236|Gammaproteobacteria,1Y6QN@135625|Pasteurellales	135625|Pasteurellales	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
k59_1581686_1	1288494.EBAPG3_11230	1.96e-29	116.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,2VV19@28216|Betaproteobacteria,374K7@32003|Nitrosomonadales	28216|Betaproteobacteria	T	Protoglobin	-	-	2.7.7.65	ko:K13590,ko:K21019	ko02025,ko04112,map02025,map04112	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF,Protoglobin
k59_1581705_2	1304883.KI912532_gene1031	3.29e-32	116.0	COG4133@1|root,COG4133@2|Bacteria,1MZPC@1224|Proteobacteria,2VMGA@28216|Betaproteobacteria,2KW6J@206389|Rhodocyclales	206389|Rhodocyclales	O	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system	ccmA	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
k59_701159_1	32024.JMTI01000035_gene861	8.39e-90	276.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2YNF8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	flgR	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_701159_2	1537917.JU82_08330	6.38e-47	159.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,42MDM@68525|delta/epsilon subdivisions,2YMIV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k59_1286891_1	1249480.B649_04145	9.73e-58	185.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,42MG3@68525|delta/epsilon subdivisions,2YMCB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	ABC-type transport system involved in resistance to organic solvents permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
k59_1286891_2	1537917.JU82_04395	6.52e-44	150.0	COG1580@1|root,COG1580@2|Bacteria,1NBUX@1224|Proteobacteria,42RSV@68525|delta/epsilon subdivisions,2YPAW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Controls the rotational direction of flagella during chemotaxis	fliL	-	-	ko:K02415	-	-	-	-	ko00000,ko02035	-	-	-	FliL
k59_1514274_1	387093.SUN_1848	1.77e-38	140.0	COG4244@1|root,COG4244@2|Bacteria,1PJNV@1224|Proteobacteria,42TI9@68525|delta/epsilon subdivisions,2YQ43@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1514278_2	1123073.KB899241_gene1974	2.23e-22	90.5	arCOG05276@1|root,3195F@2|Bacteria,1RHZA@1224|Proteobacteria,1S86B@1236|Gammaproteobacteria,1XATT@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_334475_1	709032.Sulku_0495	4.78e-132	385.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,42M94@68525|delta/epsilon subdivisions,2YMQM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
k59_1337011_1	1097668.BYI23_B006940	4.07e-68	223.0	COG1012@1|root,COG1012@2|Bacteria,1MW72@1224|Proteobacteria,2VIBR@28216|Betaproteobacteria,1K14A@119060|Burkholderiaceae	28216|Betaproteobacteria	C	belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_866848_1	1125973.JNLC01000011_gene614	1.98e-36	136.0	COG2828@1|root,COG2828@2|Bacteria,1MXVV@1224|Proteobacteria,2TQMC@28211|Alphaproteobacteria,3JWVJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	PrpF protein	-	-	5.3.2.8	ko:K16514	ko00362,ko01120,map00362,map01120	-	R07839	RC02426	ko00000,ko00001,ko01000	-	-	-	PrpF
k59_866848_2	748247.AZKH_p0507	1.33e-32	125.0	28P7P@1|root,2ZC1Y@2|Bacteria,1RBDI@1224|Proteobacteria,2W4GK@28216|Betaproteobacteria	1224|Proteobacteria	S	outer membrane porin, OprD family	-	-	-	-	-	-	-	-	-	-	-	-	OprD
k59_519789_1	1286106.MPL1_06532	2.12e-75	238.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,1RN91@1236|Gammaproteobacteria,45ZMJ@72273|Thiotrichales	72273|Thiotrichales	M	Belongs to the EPSP synthase family. MurA subfamily	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
k59_1168372_1	1236542.BALM01000001_gene147	1.87e-38	149.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2Q8P9@267890|Shewanellaceae	1236|Gammaproteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,CHASE4,EAL,GGDEF
k59_1873111_1	267608.RSc1028	6.75e-12	66.2	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,2VH1A@28216|Betaproteobacteria,1K1TR@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k59_1873111_2	395494.Galf_1735	1.47e-27	109.0	COG1232@1|root,COG1232@2|Bacteria,1NQUH@1224|Proteobacteria,2VJV1@28216|Betaproteobacteria,44V02@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Flavin containing amine oxidoreductase	hpnE	-	1.17.8.1	ko:K21677	-	-	-	-	ko00000,ko01000	-	-	-	Amino_oxidase
k59_638155_1	387093.SUN_0416	1.91e-196	566.0	COG1193@1|root,COG1193@2|Bacteria,1QUJI@1224|Proteobacteria,42P7P@68525|delta/epsilon subdivisions,2YMFB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	GO:0000018,GO:0008150,GO:0009892,GO:0010605,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0080090	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
k59_638155_2	387093.SUN_0414	7.94e-25	98.2	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,42M2J@68525|delta/epsilon subdivisions,2YMFW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	frdB	-	1.3.5.4	ko:K00245	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
k59_742041_1	717785.HYPMC_2406	9.58e-25	97.8	COG2983@1|root,COG2983@2|Bacteria,1RHMX@1224|Proteobacteria,2U99S@28211|Alphaproteobacteria,3N6XD@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Belongs to the UPF0260 family	MA20_15575	-	-	ko:K09160	-	-	-	-	ko00000	-	-	-	CxxCxxCC
k59_742041_2	1249480.B649_05280	1.34e-33	120.0	2A97K@1|root,30YCA@2|Bacteria,1Q5FD@1224|Proteobacteria,42QSX@68525|delta/epsilon subdivisions,2YP0T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the UPF0763 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF2603
k59_1397206_1	159087.Daro_0426	9.44e-151	438.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,2VIW1@28216|Betaproteobacteria,2KUH8@206389|Rhodocyclales	206389|Rhodocyclales	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groEL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_1286973_1	159087.Daro_0122	6.16e-121	347.0	COG0461@1|root,COG0461@2|Bacteria,1MW6F@1224|Proteobacteria,2VH9U@28216|Betaproteobacteria,2KUYU@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
k59_395418_1	273121.WS0596	9.53e-70	218.0	COG0847@1|root,COG0847@2|Bacteria,1P0GY@1224|Proteobacteria,42RBT@68525|delta/epsilon subdivisions,2YNWW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	dna polymerase iii	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_929733_1	159087.Daro_3311	2.86e-79	243.0	COG0631@1|root,COG0631@2|Bacteria,1N72S@1224|Proteobacteria,2VK9S@28216|Betaproteobacteria,2KVCJ@206389|Rhodocyclales	206389|Rhodocyclales	T	phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	PP2C_2
k59_281126_1	709032.Sulku_2523	2.83e-120	354.0	COG1157@1|root,COG1157@2|Bacteria,1MUH6@1224|Proteobacteria,42M0K@68525|delta/epsilon subdivisions,2YMJX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	ATP synthase	fliI	-	3.6.3.14	ko:K02412	ko02040,map02040	-	-	-	ko00000,ko00001,ko01000,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	ATP-synt_ab
k59_1104783_1	1249480.B649_06650	1.33e-91	277.0	COG2199@1|root,COG2199@2|Bacteria,1Q4Z5@1224|Proteobacteria,4306K@68525|delta/epsilon subdivisions,2YRSF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	diguanylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_1337076_1	573569.F7308_0781	8.54e-82	256.0	COG3563@1|root,COG3563@2|Bacteria,1MW0T@1224|Proteobacteria,1RPMS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Capsule polysaccharide	-	-	-	ko:K07266	-	-	-	-	ko00000	-	-	-	Capsule_synth
k59_100026_1	28229.ND2E_2794	4.92e-15	79.3	COG2366@1|root,COG2366@2|Bacteria,1QUW6@1224|Proteobacteria,1T23A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	antibiotic biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	DM13
k59_395428_1	1537917.JU82_11825	1.11e-143	417.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,42M14@68525|delta/epsilon subdivisions,2YMWB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Biotin carboxylase	pycA	-	6.3.4.14,6.4.1.1,6.4.1.2	ko:K01959,ko:K01961	ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko01230,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212,map01230	M00082,M00173,M00376,M00620	R00344,R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
k59_167848_1	709032.Sulku_1224	2.23e-126	374.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2YMIX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE
k59_355566_3	159087.Daro_0116	2.06e-95	286.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,2VIR9@28216|Betaproteobacteria,2KUHG@206389|Rhodocyclales	206389|Rhodocyclales	D	Rod shape-determining protein MreB	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
k59_1412552_1	159087.Daro_4052	1.83e-100	294.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,2VSP6@28216|Betaproteobacteria,2KWKV@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the ompA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
k59_1764784_2	1304883.KI912532_gene1231	2.54e-54	170.0	2DNV8@1|root,32ZAX@2|Bacteria,1R3MW@1224|Proteobacteria,2VWAR@28216|Betaproteobacteria,2KWYT@206389|Rhodocyclales	206389|Rhodocyclales	S	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
k59_766145_1	159087.Daro_0105	8.59e-42	140.0	COG1977@1|root,COG1977@2|Bacteria,1PT86@1224|Proteobacteria,2VYZI@28216|Betaproteobacteria,2KZFC@206389|Rhodocyclales	206389|Rhodocyclales	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_766145_2	159087.Daro_0104	7.29e-78	248.0	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,2VH50@28216|Betaproteobacteria,2KV59@206389|Rhodocyclales	206389|Rhodocyclales	I	poly(R)-hydroxyalkanoic acid synthase	-	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,PhaC_N
k59_121138_2	537972.ABQU01000007_gene117	7.41e-28	114.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,42M35@68525|delta/epsilon subdivisions,2YM7I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0354	DXP_synthase_N,Transket_pyr,Transketolase_C
k59_238475_1	159087.Daro_3943	1.45e-113	347.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,2VIYB@28216|Betaproteobacteria,2KV7P@206389|Rhodocyclales	206389|Rhodocyclales	C	Malic enzyme	-	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
k59_1530749_1	709032.Sulku_0718	9.94e-68	213.0	COG0457@1|root,COG0457@2|Bacteria,1Q60C@1224|Proteobacteria,42X29@68525|delta/epsilon subdivisions,2YQQA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Anaphase-promoting complex, cyclosome, subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC3
k59_532858_1	204773.HEAR1386	4.34e-62	203.0	COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,2VJ87@28216|Betaproteobacteria,472QN@75682|Oxalobacteraceae	28216|Betaproteobacteria	U	Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate	dctA	-	-	ko:K11103	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.23.1.3,2.A.23.1.6,2.A.23.1.7	-	-	SDF
k59_1530753_1	666681.M301_2464	1.41e-89	271.0	COG0596@1|root,COG0596@2|Bacteria,1MWW8@1224|Proteobacteria,2VIEF@28216|Betaproteobacteria,2KM4G@206350|Nitrosomonadales	206350|Nitrosomonadales	E	Belongs to the peptidase S33 family	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
k59_1236899_1	709032.Sulku_0655	4.42e-96	290.0	COG0245@1|root,COG1211@1|root,COG0245@2|Bacteria,COG1211@2|Bacteria,1MVHA@1224|Proteobacteria,42MJ6@68525|delta/epsilon subdivisions,2YMEK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF)	ispDF	-	2.7.7.60,4.6.1.12	ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
k59_1824424_1	1172190.M947_05325	2.68e-102	327.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,42NHZ@68525|delta/epsilon subdivisions,2YMTE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	5-methyltetrahydrofolate--homocysteine methyltransferase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
k59_1530782_1	1304883.KI912532_gene201	2.73e-22	88.6	COG2345@1|root,COG2345@2|Bacteria,1N9W3@1224|Proteobacteria,2VWG0@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1530782_2	159087.Daro_1532	0.000126	43.1	COG5490@1|root,COG5490@2|Bacteria,1R4SV@1224|Proteobacteria,2VQP2@28216|Betaproteobacteria,2KW96@206389|Rhodocyclales	206389|Rhodocyclales	S	Phasin protein	-	-	-	-	-	-	-	-	-	-	-	-	Phasin_2
k59_532902_1	709032.Sulku_0629	4.43e-99	308.0	COG1289@1|root,COG1289@2|Bacteria,1MX9H@1224|Proteobacteria,43F33@68525|delta/epsilon subdivisions,2YRBI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Aromatic acid exporter family member 1	-	-	-	-	-	-	-	-	-	-	-	-	FUSC
k59_296735_1	709032.Sulku_1427	5.34e-104	303.0	COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,42RJR@68525|delta/epsilon subdivisions,2YP3U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
k59_296735_2	709032.Sulku_1426	3e-81	242.0	COG1246@1|root,COG1246@2|Bacteria,1RHT7@1224|Proteobacteria,42SGE@68525|delta/epsilon subdivisions,2YPNW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	acetyltransferase	-	-	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
k59_5038_2	1150621.SMUL_3300	2.79e-18	84.3	COG1351@1|root,COG1351@2|Bacteria,1Q73I@1224|Proteobacteria,42N3X@68525|delta/epsilon subdivisions,2YMHF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
k59_238527_1	159087.Daro_2400	7.18e-104	317.0	2DBM3@1|root,2Z9WX@2|Bacteria,1R676@1224|Proteobacteria,2VPUB@28216|Betaproteobacteria,2KWS6@206389|Rhodocyclales	206389|Rhodocyclales	S	TIGRFAM PEP-CTERM system associated protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_296752_1	1437824.BN940_00136	3.4e-91	275.0	COG1091@1|root,COG1091@2|Bacteria,1MUXM@1224|Proteobacteria,2VI50@28216|Betaproteobacteria,3T3JT@506|Alcaligenaceae	28216|Betaproteobacteria	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
k59_1236994_1	159087.Daro_0241	6.16e-107	317.0	COG3221@1|root,COG3221@2|Bacteria,1R4SK@1224|Proteobacteria,2VQN6@28216|Betaproteobacteria,2KW7Y@206389|Rhodocyclales	206389|Rhodocyclales	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
k59_1060061_1	1218074.BAXZ01000015_gene3216	0.00028	42.7	COG0179@1|root,COG0179@2|Bacteria,1MVFA@1224|Proteobacteria,2VHG8@28216|Betaproteobacteria,1K027@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	fumarylacetoacetate (FAA) hydrolase	-	-	3.7.1.20	ko:K16165	ko00350,ko01100,ko01120,map00350,map01100,map01120	-	R01085	RC00326,RC00446	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
k59_532981_1	709032.Sulku_0270	7.48e-184	534.0	COG1034@1|root,COG1034@2|Bacteria,1RCFT@1224|Proteobacteria,42NK4@68525|delta/epsilon subdivisions,2YNI6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G)	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4_10,Molybdopterin,NADH-G_4Fe-4S_3
k59_1824532_1	1165841.SULAR_00620	2.06e-26	109.0	COG4664@1|root,COG4665@1|root,COG4664@2|Bacteria,COG4665@2|Bacteria,1R4MZ@1224|Proteobacteria,42MQU@68525|delta/epsilon subdivisions,2YMC7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	TRAP transporter, DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM,DctQ
k59_1824532_2	563040.Saut_0945	4.16e-52	169.0	COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,42SCS@68525|delta/epsilon subdivisions,2YPIF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	Tripartite ATP-independent periplasmic transporter DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
k59_62246_1	1249480.B649_09690	1.64e-113	327.0	COG3260@1|root,COG3260@2|Bacteria,1QUBE@1224|Proteobacteria,42NH3@68525|delta/epsilon subdivisions,2YMSW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
k59_62246_2	1249480.B649_09685	4.13e-15	69.7	COG0852@1|root,COG0852@2|Bacteria,1Q346@1224|Proteobacteria,42WRC@68525|delta/epsilon subdivisions,2YQIS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Respiratory-chain NADH dehydrogenase, 30 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_30kDa
k59_1295176_1	1249480.B649_06080	6.79e-31	121.0	COG2984@1|root,COG2984@2|Bacteria,1PGQI@1224|Proteobacteria,43496@68525|delta/epsilon subdivisions,2YRIT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	ABC transporter substrate binding protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_650511_1	572477.Alvin_1986	8.47e-83	255.0	COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,1RMKU@1236|Gammaproteobacteria,1WWHV@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
k59_1001983_1	1304883.KI912532_gene2962	1.29e-111	327.0	COG0451@1|root,COG0451@2|Bacteria,1MVE4@1224|Proteobacteria,2VH69@28216|Betaproteobacteria,2KURF@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose	hldD	-	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase
k59_590819_1	1249480.B649_03035	1.18e-134	390.0	COG0475@1|root,COG0475@2|Bacteria,1R7K4@1224|Proteobacteria,42MF1@68525|delta/epsilon subdivisions,2YM86@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Na H antiporter	kefB_1	-	-	-	-	-	-	-	-	-	-	iIT341.HP1183	Na_H_Exchanger
k59_1060108_1	65393.PCC7424_2210	3.47e-05	45.4	COG0696@1|root,COG0696@2|Bacteria,1G1UT@1117|Cyanobacteria,3KHAA@43988|Cyanothece	1117|Cyanobacteria	F	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.yibO	Metalloenzyme,Phosphodiest,iPGM_N
k59_1060108_2	553207.HMPREF0299_5382	1.36e-05	50.8	COG0476@1|root,COG0476@2|Bacteria,2GJB6@201174|Actinobacteria,22JUD@1653|Corynebacteriaceae	201174|Actinobacteria	H	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2	moeB	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
k59_1001992_1	1304883.KI912532_gene1719	1.04e-107	313.0	COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,2VJVJ@28216|Betaproteobacteria,2KV35@206389|Rhodocyclales	206389|Rhodocyclales	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
k59_1178088_1	1537917.JU82_05655	1.52e-153	433.0	COG0433@1|root,COG0433@2|Bacteria,1Q4H7@1224|Proteobacteria,42Z6M@68525|delta/epsilon subdivisions,2YR7W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COG0433 Predicted ATPase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_707643_1	1265503.KB905162_gene3569	2.02e-20	96.7	COG0715@1|root,COG2199@1|root,COG0715@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,NMT1,dCache_1,dCache_3
k59_884370_1	159087.Daro_1954	5.22e-71	230.0	COG0443@1|root,COG0443@2|Bacteria,1MVQI@1224|Proteobacteria,2VHGV@28216|Betaproteobacteria,2KUV2@206389|Rhodocyclales	206389|Rhodocyclales	O	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB	hscA	-	-	ko:K04044	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
k59_884370_2	159087.Daro_1953	8.11e-23	92.0	COG1076@1|root,COG1076@2|Bacteria,1RHZX@1224|Proteobacteria,2VSD5@28216|Betaproteobacteria,2KWCY@206389|Rhodocyclales	206389|Rhodocyclales	O	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA	hscB	-	-	ko:K04082	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	HSCB_C
k59_1471122_1	1304883.KI912532_gene220	6.14e-60	191.0	COG1414@1|root,COG1414@2|Bacteria,1MUNW@1224|Proteobacteria,2VHB6@28216|Betaproteobacteria,2KUMZ@206389|Rhodocyclales	206389|Rhodocyclales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
k59_1471122_2	1211115.ALIQ01000017_gene4570	2.1e-38	137.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,2TR9H@28211|Alphaproteobacteria,3NAK4@45404|Beijerinckiaceae	28211|Alphaproteobacteria	C	Cysteine-rich domain	-	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
k59_1764929_2	1537917.JU82_06820	6.45e-16	77.4	COG1315@1|root,COG1315@2|Bacteria,1R5P6@1224|Proteobacteria,42MAS@68525|delta/epsilon subdivisions,2YM7Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Flagellar Assembly Protein A	-	-	-	-	-	-	-	-	-	-	-	-	FapA
k59_5171_1	709032.Sulku_1002	2.14e-107	325.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,42NC6@68525|delta/epsilon subdivisions,2YMJV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
k59_1002011_1	159087.Daro_0722	4.17e-140	400.0	COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,2VHPX@28216|Betaproteobacteria,2KU78@206389|Rhodocyclales	206389|Rhodocyclales	N	flagellar motor	-	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
k59_1824605_1	1537917.JU82_10065	1.74e-127	380.0	COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,42RCJ@68525|delta/epsilon subdivisions,2YNX9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG4775 Outer membrane protein protective antigen OMA87	-	-	-	ko:K07278	-	-	-	-	ko00000,ko02000	1.B.33.2.4	-	-	Bac_surface_Ag,POTRA
k59_1060131_1	438753.AZC_3598	2.86e-68	226.0	COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1QT52@1224|Proteobacteria,2TVNI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Toprim-like	-	-	3.6.4.12	ko:K17680	-	-	-	-	ko00000,ko01000,ko03029	-	-	-	DnaB_C,Toprim_2
k59_884385_1	1537917.JU82_02015	4.56e-60	193.0	COG3907@1|root,COG3907@2|Bacteria,1MY7B@1224|Proteobacteria,42RAC@68525|delta/epsilon subdivisions,2YQ1I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COGs COG3907 PAP2 (acid phosphatase) superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
k59_5183_2	1249480.B649_08725	2.59e-120	347.0	2AIDI@1|root,31TAR@2|Bacteria,1QR0P@1224|Proteobacteria,42TWA@68525|delta/epsilon subdivisions,2YSYQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PilO
k59_5183_3	709032.Sulku_0723	2.13e-82	259.0	COG4972@1|root,COG4972@2|Bacteria,1QA6M@1224|Proteobacteria,42NDB@68525|delta/epsilon subdivisions,2YMP2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Pilus assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_62301_1	1249480.B649_04235	6.55e-144	417.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,42MXQ@68525|delta/epsilon subdivisions,2YM9P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0098	PALP,Thr_synth_N
k59_1530985_2	159087.Daro_2480	1.33e-98	314.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2VHCZ@28216|Betaproteobacteria,2KUGU@206389|Rhodocyclales	206389|Rhodocyclales	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	cusA	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
k59_296844_1	574966.KB898648_gene802	1.39e-14	83.6	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria	1224|Proteobacteria	NT	Methyl-accepting chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,MCPsignal,dCache_1
k59_707689_1	1168067.JAGP01000001_gene967	4.63e-86	270.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,1RN0R@1236|Gammaproteobacteria,45ZPK@72273|Thiotrichales	72273|Thiotrichales	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
k59_1531003_1	159087.Daro_3125	4.28e-42	149.0	COG0840@1|root,COG0840@2|Bacteria,1RBQH@1224|Proteobacteria,2VNG3@28216|Betaproteobacteria,2KVTI@206389|Rhodocyclales	1224|Proteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
k59_1531003_2	159087.Daro_3121	2.85e-61	204.0	COG4579@1|root,COG4579@2|Bacteria,1MVRB@1224|Proteobacteria,2VJMA@28216|Betaproteobacteria,2KUNY@206389|Rhodocyclales	206389|Rhodocyclales	F	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation	aceK	-	2.7.11.5	ko:K00906	-	-	-	-	ko00000,ko01000	-	-	-	AceK
k59_828861_2	1304883.KI912532_gene517	3.69e-57	183.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2VJM6@28216|Betaproteobacteria,2KVIX@206389|Rhodocyclales	206389|Rhodocyclales	E	branched-chain amino acid	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
k59_1122517_2	1249480.B649_01460	1.15e-36	137.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,42MB1@68525|delta/epsilon subdivisions,2YMVC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
k59_476611_1	1249480.B649_05780	5.65e-106	313.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,42M0C@68525|delta/epsilon subdivisions,2YM8W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
k59_709736_1	709032.Sulku_0442	5.32e-39	140.0	COG0840@1|root,COG0840@2|Bacteria,1QZ1R@1224|Proteobacteria,42SSJ@68525|delta/epsilon subdivisions,2YPF5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	transmembrane signaling receptor activity	-	-	-	-	-	-	-	-	-	-	-	-	dCache_3
k59_709736_2	1537917.JU82_07975	9.54e-127	369.0	COG1377@1|root,COG1377@2|Bacteria,1MUWI@1224|Proteobacteria,42NKR@68525|delta/epsilon subdivisions,2YMU1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhB	-	-	ko:K02401	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_2
k59_1122527_1	717773.Thicy_0833	2.95e-89	281.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,1RPX3@1236|Gammaproteobacteria,461JQ@72273|Thiotrichales	72273|Thiotrichales	F	Belongs to the 5'-nucleotidase family	-	-	-	ko:K17224	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	5_nucleotid_C
k59_358164_1	1537917.JU82_03440	4.26e-19	87.8	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,42NYV@68525|delta/epsilon subdivisions,2YN1D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	pyridine nucleotide-disulfide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_358164_2	1150621.SMUL_1305	1.27e-07	51.6	COG0375@1|root,COG0375@2|Bacteria,1MZJH@1224|Proteobacteria,42TGG@68525|delta/epsilon subdivisions,2YPWP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
k59_593564_2	1165841.SULAR_00360	3.43e-124	373.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,42MPK@68525|delta/epsilon subdivisions,2YMFX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,SurA_N_3
k59_64532_1	159087.Daro_1471	1.3e-135	392.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1MWHZ@1224|Proteobacteria,2VH9M@28216|Betaproteobacteria,2KV6W@206389|Rhodocyclales	206389|Rhodocyclales	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrome_CBB3
k59_1767524_1	709032.Sulku_0904	8.24e-45	161.0	COG1315@1|root,COG1315@2|Bacteria,1R5P6@1224|Proteobacteria,42MAS@68525|delta/epsilon subdivisions,2YM7Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Flagellar Assembly Protein A	-	-	-	-	-	-	-	-	-	-	-	-	FapA
k59_1767524_2	929558.SMGD1_0918	2.38e-06	48.9	COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,42NTK@68525|delta/epsilon subdivisions,2YNFT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the UPF0061 (SELO) family	-	-	-	-	-	-	-	-	-	-	-	-	UPF0061
k59_887008_1	1304883.KI912532_gene2632	1.73e-115	338.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,2VIM9@28216|Betaproteobacteria,2KUG4@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
k59_1474079_1	1537917.JU82_11020	8.74e-50	172.0	COG3203@1|root,COG3203@2|Bacteria	2|Bacteria	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	oprD	-	-	ko:K08720,ko:K18093	ko01501,ko02020,ko05111,map01501,map02020,map05111	M00745	-	-	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	1.B.1.2.1,1.B.25.1.1	-	iJN746.PP_1206	Alginate_exp,BBP2,OprD,Porin_4
k59_1062711_1	159087.Daro_3026	6.67e-25	98.6	COG3577@1|root,COG3577@2|Bacteria,1N2PE@1224|Proteobacteria,2VS6Z@28216|Betaproteobacteria,2KWGP@206389|Rhodocyclales	206389|Rhodocyclales	S	gag-polyprotein putative aspartyl protease	-	-	-	ko:K06985	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	gag-asp_proteas
k59_1062711_2	159087.Daro_3027	8.3e-55	177.0	COG0518@1|root,COG0518@2|Bacteria,1MUDH@1224|Proteobacteria,2VJEI@28216|Betaproteobacteria,2KWJH@206389|Rhodocyclales	206389|Rhodocyclales	F	Glutamine amidotransferase class-I	-	-	-	-	-	-	-	-	-	-	-	-	GATase
k59_241224_1	709032.Sulku_1362	9.2e-72	224.0	COG0791@1|root,COG0791@2|Bacteria,1N0EE@1224|Proteobacteria,42V3C@68525|delta/epsilon subdivisions,2YQCX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	NlpC/P60 family	-	-	3.4.17.13	ko:K13694,ko:K13695	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60,SPOR
k59_181625_1	1249480.B649_02125	1.06e-92	286.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,42NIH@68525|delta/epsilon subdivisions,2YMVT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	FP	Guanosine pentaphosphate phosphohydrolase	gppA	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
k59_946395_1	1249480.B649_06095	2.69e-07	50.8	COG0674@1|root,COG0674@2|Bacteria,1NBSJ@1224|Proteobacteria,42MS1@68525|delta/epsilon subdivisions,2YMD2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Oxidoreductase	oorA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
k59_946395_2	709032.Sulku_1458	4.66e-76	226.0	COG1146@1|root,COG1146@2|Bacteria,1NJJD@1224|Proteobacteria,42TVE@68525|delta/epsilon subdivisions,2YPUN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	2-oxoglutarate acceptor oxidoreductase	oorD	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Fer4_6,Fer4_7
k59_946395_3	709032.Sulku_1459	5.94e-14	66.2	COG2608@1|root,COG2608@2|Bacteria,1N81B@1224|Proteobacteria,42VKI@68525|delta/epsilon subdivisions,2YQD5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Heavy-metal-associated domain	-	-	-	-	-	-	-	-	-	-	-	-	HMA
k59_1180730_1	159087.Daro_1748	2.19e-150	431.0	COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,2VHJY@28216|Betaproteobacteria,2KVYE@206389|Rhodocyclales	206389|Rhodocyclales	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
k59_887069_2	132113.XP_003493944.1	1.37e-19	87.8	COG0343@1|root,KOG3908@2759|Eukaryota,398WW@33154|Opisthokonta,3CD3V@33208|Metazoa,3DDEC@33213|Bilateria	33208|Metazoa	J	tRNA-guanine transglycosylation	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1474143_1	709032.Sulku_1643	5.24e-39	147.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2YMW5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,MCPsignal,dCache_2,sCache_2
k59_1474143_2	326298.Suden_1940	4.25e-32	122.0	COG1352@1|root,COG1352@2|Bacteria,1MVP3@1224|Proteobacteria,42PR6@68525|delta/epsilon subdivisions,2YNJY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	methyltransferase	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR
k59_653687_1	90814.KL370891_gene626	1.35e-38	148.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,45ZUH@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_1240571_1	1537917.JU82_05115	1.93e-159	460.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,42NBJ@68525|delta/epsilon subdivisions,2YMTY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Mg chelatase-related protein	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
k59_1180765_1	709032.Sulku_1464	5.64e-114	347.0	COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,42MY0@68525|delta/epsilon subdivisions,2YMT1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
k59_241262_1	675813.VIB_000221	2.26e-35	136.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,1RMTF@1236|Gammaproteobacteria,1XSUS@135623|Vibrionales	135623|Vibrionales	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
k59_241262_2	1177181.T9A_02986	4.12e-48	160.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,1S60E@1236|Gammaproteobacteria,1XK4C@135619|Oceanospirillales	135619|Oceanospirillales	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
k59_241262_3	1123228.AUIH01000007_gene2577	8.49e-25	109.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XHGD@135619|Oceanospirillales	135619|Oceanospirillales	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_1122627_1	709032.Sulku_2414	7.53e-90	281.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,42MMR@68525|delta/epsilon subdivisions,2YMF0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	GM	Polysaccharide biosynthesis protein	pglF	-	4.2.1.135	ko:K15912	ko00520,map00520	-	-	-	ko00000,ko00001,ko01000	-	-	-	Polysacc_synt_2
k59_1005369_1	583345.Mmol_0667	1.21e-128	399.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,2VHTE@28216|Betaproteobacteria,2KKQX@206350|Nitrosomonadales	206350|Nitrosomonadales	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
k59_1240596_1	159087.Daro_1000	1.44e-77	249.0	COG3284@1|root,COG3284@2|Bacteria,1NRG5@1224|Proteobacteria,2VICI@28216|Betaproteobacteria,2KV0U@206389|Rhodocyclales	206389|Rhodocyclales	K	Transcriptional activator of acetoin glycerol metabolism	-	-	-	ko:K21405	-	-	-	-	ko00000,ko03000	-	-	-	GAF,HTH_8,Sigma54_activat
k59_1240596_2	1382306.JNIM01000001_gene3450	1.12e-06	50.1	COG0466@1|root,COG0466@2|Bacteria,2G5TZ@200795|Chloroflexi	200795|Chloroflexi	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_241283_1	709032.Sulku_1638	2.12e-38	144.0	COG2199@1|root,COG2202@1|root,COG2199@2|Bacteria,COG2202@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42T0Q@68525|delta/epsilon subdivisions,2YR76@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_9
k59_417356_2	709032.Sulku_2550	1.97e-40	141.0	2C2AA@1|root,2ZAYY@2|Bacteria,1RD8I@1224|Proteobacteria,42N13@68525|delta/epsilon subdivisions,2YN8K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	TraT complement resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	TraT
k59_1767618_1	709032.Sulku_0310	4.07e-31	118.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,42N4K@68525|delta/epsilon subdivisions,2YMVY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	HI0933 family	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
k59_1767618_2	709032.Sulku_0309	1.12e-62	197.0	COG2717@1|root,COG2717@2|Bacteria,1RDUP@1224|Proteobacteria,42VZ2@68525|delta/epsilon subdivisions,2YQGP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	PFAM Ferric reductase domain protein transmembrane component domain	-	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
k59_1708891_1	709032.Sulku_1645	8.31e-59	187.0	COG1651@1|root,COG1651@2|Bacteria,1Q684@1224|Proteobacteria,432K4@68525|delta/epsilon subdivisions,2YSQB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1708891_2	1249480.B649_03965	5.19e-33	128.0	COG1033@1|root,COG1033@2|Bacteria	2|Bacteria	S	growth of symbiont in host cell	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_887111_1	1537917.JU82_11190	1.23e-89	266.0	COG0431@1|root,COG0431@2|Bacteria,1RH7F@1224|Proteobacteria,42X6I@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
k59_887111_2	471854.Dfer_0269	8.66e-42	149.0	COG1028@1|root,COG1028@2|Bacteria,4NKYV@976|Bacteroidetes,47P1D@768503|Cytophagia	976|Bacteroidetes	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k59_653739_1	159087.Daro_1037	3.01e-128	371.0	COG0582@1|root,COG0582@2|Bacteria,1MWBN@1224|Proteobacteria,2VK8Q@28216|Betaproteobacteria,2KXFF@206389|Rhodocyclales	206389|Rhodocyclales	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_integrase
k59_887113_1	709032.Sulku_0870	4.46e-173	496.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,42ME5@68525|delta/epsilon subdivisions,2YMKK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
k59_1767625_1	1304872.JAGC01000009_gene174	5.65e-44	167.0	COG0642@1|root,COG1352@1|root,COG1352@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WIR4@28221|Deltaproteobacteria,2M7T3@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	5TM-5TMR_LYT,CheB_methylest,CheR,CheR_N,GAF_2,HATPase_c,HisKA,PAS,PAS_4,Response_reg
k59_1122686_1	1537917.JU82_09450	1.08e-80	247.0	COG2996@1|root,COG2996@2|Bacteria,1MXC3@1224|Proteobacteria,42P2A@68525|delta/epsilon subdivisions,2YMVD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	S1 domain	-	-	-	ko:K00243	-	-	-	-	ko00000	-	-	-	S1_2
k59_124456_2	709032.Sulku_1890	4.44e-24	104.0	COG0457@1|root,COG4783@1|root,COG0457@2|Bacteria,COG4783@2|Bacteria,1QV15@1224|Proteobacteria,42NKI@68525|delta/epsilon subdivisions,2YMKG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	COG0457 FOG TPR repeat	pflB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_6,TPR_8
k59_1240667_1	159087.Daro_0008	8.34e-72	242.0	COG0784@1|root,COG2198@1|root,COG5000@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG5000@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,2WGIN@28216|Betaproteobacteria,2KZWN@206389|Rhodocyclales	206389|Rhodocyclales	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_4,PAS_9,Response_reg
k59_124463_1	1249480.B649_05910	1.76e-129	384.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,42M1S@68525|delta/epsilon subdivisions,2YMEF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	penicillin-binding protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
k59_1415860_2	946483.Cenrod_1892	4.06e-29	115.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,2VH1F@28216|Betaproteobacteria,4AD3Y@80864|Comamonadaceae	28216|Betaproteobacteria	T	Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
k59_1062859_1	709032.Sulku_1392	2.73e-125	385.0	COG0755@1|root,COG1333@1|root,COG0755@2|Bacteria,COG1333@2|Bacteria,1RG0A@1224|Proteobacteria,42N37@68525|delta/epsilon subdivisions,2YMXW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Cytochrome c biogenesis protein	ccsBA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
k59_241345_1	1537917.JU82_03855	1.42e-115	344.0	COG1463@1|root,COG1463@2|Bacteria,1RFFS@1224|Proteobacteria,42P4P@68525|delta/epsilon subdivisions,2YNNZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
k59_1827785_1	159087.Daro_1196	3.14e-78	238.0	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,2VIUV@28216|Betaproteobacteria,2KV37@206389|Rhodocyclales	206389|Rhodocyclales	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
k59_1827785_2	159087.Daro_1195	2.27e-29	110.0	COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,2VJ8E@28216|Betaproteobacteria,2KVBA@206389|Rhodocyclales	206389|Rhodocyclales	O	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate	ate	-	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	ATE_C,ATE_N
k59_241346_1	387093.SUN_1205	6.25e-39	144.0	COG2199@1|root,COG3706@2|Bacteria,1NR1I@1224|Proteobacteria,43AGD@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_1
k59_181757_1	1537917.JU82_00620	5.01e-93	274.0	COG2077@1|root,COG2077@2|Bacteria,1RAJ9@1224|Proteobacteria,42RE8@68525|delta/epsilon subdivisions,2YP3Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	tpx	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	Redoxin
k59_1297697_1	159087.Daro_2860	5.34e-112	332.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,2VIJF@28216|Betaproteobacteria,2KVDB@206389|Rhodocyclales	206389|Rhodocyclales	H	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
k59_768786_2	1266925.JHVX01000009_gene90	3.96e-21	87.8	2DMYE@1|root,32UDK@2|Bacteria,1NNTZ@1224|Proteobacteria,2W3RQ@28216|Betaproteobacteria,37398@32003|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_476866_1	1249480.B649_06085	5.31e-85	253.0	COG1014@1|root,COG1014@2|Bacteria,1R8XG@1224|Proteobacteria,42NPD@68525|delta/epsilon subdivisions,2YMM0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	oxidoreductase	oorC	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
k59_1827807_1	1537917.JU82_00520	7.32e-277	766.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,42M20@68525|delta/epsilon subdivisions,2YMDG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
k59_1827807_2	1249480.B649_00470	9.25e-21	86.3	COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,42RHA@68525|delta/epsilon subdivisions,2YNX4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
k59_1297725_1	387093.SUN_0907	2.08e-118	375.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2YMRQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_476891_1	743299.Acife_1732	8.24e-06	52.8	COG0671@1|root,COG0671@2|Bacteria,1NIPK@1224|Proteobacteria,1T92C@1236|Gammaproteobacteria,2NDT4@225057|Acidithiobacillales	225057|Acidithiobacillales	I	PAP2 superfamily	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
k59_476891_2	1249480.B649_00580	4.69e-23	95.9	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,42M9X@68525|delta/epsilon subdivisions,2YMQ1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
k59_181793_1	1123517.JOMR01000001_gene471	9.69e-12	74.3	COG0840@1|root,COG2972@1|root,COG0840@2|Bacteria,COG2972@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria	1224|Proteobacteria	NT	chemotaxis, protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,CZB,HAMP,MCPsignal,PAS_3,PAS_9,dCache_1
k59_946611_1	587753.EY04_25375	1e-16	84.7	COG1432@1|root,COG1432@2|Bacteria,1MX5C@1224|Proteobacteria,1RSP8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	OST-HTH/LOTUS domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
k59_299239_1	1537915.JU57_05175	8.87e-21	97.4	COG1404@1|root,COG2304@1|root,COG2931@1|root,COG3210@1|root,COG5625@1|root,COG1404@2|Bacteria,COG2304@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG5625@2|Bacteria,1MU7T@1224|Proteobacteria,42PPF@68525|delta/epsilon subdivisions,2YRRN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_124551_1	412597.AEPN01000014_gene2353	2.42e-73	234.0	COG1027@1|root,COG1027@2|Bacteria,1R9JY@1224|Proteobacteria,2TVZD@28211|Alphaproteobacteria,2PU29@265|Paracoccus	28211|Alphaproteobacteria	E	Fumarase C C-terminus	aspA	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1
k59_946619_1	1249480.B649_04825	4.87e-67	228.0	COG0755@1|root,COG1333@1|root,COG0755@2|Bacteria,COG1333@2|Bacteria,1RG0A@1224|Proteobacteria,42N37@68525|delta/epsilon subdivisions,2YMXW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Cytochrome c biogenesis protein	ccsBA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
k59_1767730_1	709032.Sulku_1841	3.11e-110	324.0	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,42NPG@68525|delta/epsilon subdivisions,2YMG4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iIT341.HP1375	Acetyltransf_11,Hexapep
k59_8266_1	305700.B447_01751	8.55e-80	249.0	COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,2VKIS@28216|Betaproteobacteria,2KVRE@206389|Rhodocyclales	206389|Rhodocyclales	S	FAD-dependent pyridine	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
k59_417482_1	159087.Daro_1127	9.71e-149	434.0	COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,2VHHJ@28216|Betaproteobacteria,2KUTN@206389|Rhodocyclales	206389|Rhodocyclales	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
k59_1062945_1	1123514.KB905902_gene229	3.15e-105	315.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RPAB@1236|Gammaproteobacteria,4612S@72273|Thiotrichales	72273|Thiotrichales	C	Cysteine-rich domain	-	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_7,Fer4_8
k59_1062953_1	317025.Tcr_0998	3.54e-28	112.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,1RMU9@1236|Gammaproteobacteria,46021@72273|Thiotrichales	72273|Thiotrichales	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
k59_1062953_2	765910.MARPU_15125	2.05e-16	81.6	COG4137@1|root,COG4137@2|Bacteria,1R3YD@1224|Proteobacteria,1RPUQ@1236|Gammaproteobacteria,1WX1P@135613|Chromatiales	135613|Chromatiales	S	Cytochrome c assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
k59_1534225_1	582744.Msip34_2205	8.46e-125	389.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2VHCZ@28216|Betaproteobacteria,2KMG8@206350|Nitrosomonadales	206350|Nitrosomonadales	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
k59_1767757_1	709032.Sulku_0781	4.5e-08	53.5	COG0457@1|root,COG0457@2|Bacteria,1N9AG@1224|Proteobacteria,42QUG@68525|delta/epsilon subdivisions,2YP2D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF3137)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3137
k59_1767757_2	1249480.B649_08215	7.84e-81	244.0	COG1739@1|root,COG1739@2|Bacteria,1NFJC@1224|Proteobacteria,42T7W@68525|delta/epsilon subdivisions,2YPM6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	hmm pf01205	-	-	-	-	-	-	-	-	-	-	-	-	DUF1949,UPF0029
k59_593876_1	709032.Sulku_0398	5.83e-53	168.0	COG0023@1|root,COG0023@2|Bacteria,1Q2ID@1224|Proteobacteria,42VSB@68525|delta/epsilon subdivisions,2YQ8F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Translation initiation factor SUI1	-	-	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
k59_593876_2	1537917.JU82_05250	2.26e-33	115.0	COG4728@1|root,COG4728@2|Bacteria,1N6NP@1224|Proteobacteria,42WCY@68525|delta/epsilon subdivisions,2YSK3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF1653)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1653
k59_181858_1	387093.SUN_0350	8.47e-93	291.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,43BJ8@68525|delta/epsilon subdivisions,2YMMJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	penicillin-binding protein	pbpA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
k59_768903_1	160488.PP_2293	4.45e-44	159.0	COG5410@1|root,COG5410@2|Bacteria,1N0W2@1224|Proteobacteria,1S03G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_124625_1	765698.Mesci_1031	2.27e-74	236.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,2TT2J@28211|Alphaproteobacteria,43J03@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	Ammonium Transporter	amtB	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
k59_1240827_1	1121935.AQXX01000138_gene3148	0.000393	48.1	COG1330@1|root,COG1330@2|Bacteria,1MWTI@1224|Proteobacteria,1RNT0@1236|Gammaproteobacteria,1XHMF@135619|Oceanospirillales	135619|Oceanospirillales	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity	recC	-	3.1.11.5	ko:K03583	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_V_gamma
k59_184164_1	580332.Slit_1459	2.05e-75	242.0	COG3287@1|root,COG3287@2|Bacteria,1R825@1224|Proteobacteria,2VPKS@28216|Betaproteobacteria,44W6E@713636|Nitrosomonadales	28216|Betaproteobacteria	S	FIST_C	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
k59_1418761_1	1304883.KI912532_gene1793	6.57e-40	151.0	COG0845@1|root,COG0845@2|Bacteria,1QN99@1224|Proteobacteria,2VQR3@28216|Betaproteobacteria,2KWDC@206389|Rhodocyclales	206389|Rhodocyclales	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
k59_301346_1	397945.Aave_2372	5.14e-71	238.0	COG5301@1|root,COG5301@2|Bacteria,1N4CW@1224|Proteobacteria	1224|Proteobacteria	G	cellulose 1,4-beta-cellobiosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Phage_T7_tail
k59_479865_1	709032.Sulku_1240	3.92e-119	356.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,43AD6@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k59_1770212_2	159087.Daro_3779	2.03e-15	75.1	COG4447@1|root,COG4447@2|Bacteria,1R5ZV@1224|Proteobacteria,2VNAP@28216|Betaproteobacteria,2KVGC@206389|Rhodocyclales	206389|Rhodocyclales	S	Photosynthesis system II assembly factor YCF48	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
k59_1243691_1	62928.azo1390	4.2e-34	126.0	COG0226@1|root,COG0226@2|Bacteria,1MUAZ@1224|Proteobacteria,2VIJV@28216|Betaproteobacteria,2KVUC@206389|Rhodocyclales	206389|Rhodocyclales	P	Part of the ABC transporter complex PstSACB involved in phosphate import	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
k59_1243691_2	159087.Daro_3561	2.47e-36	127.0	2E4XE@1|root,32ZRB@2|Bacteria,1N7HI@1224|Proteobacteria,2VVPN@28216|Betaproteobacteria,2KXGK@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1477151_1	1366050.N234_25045	5.73e-162	462.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VJJD@28216|Betaproteobacteria,1K1EB@119060|Burkholderiaceae	28216|Betaproteobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
k59_1065794_1	1537917.JU82_08620	2.81e-13	68.6	COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,42M8J@68525|delta/epsilon subdivisions,2YNGB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member	recD	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2,Viral_helicase1
k59_1065794_2	987059.RBXJA2T_04348	2.35e-31	120.0	COG0784@1|root,COG2198@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,1NC9X@1224|Proteobacteria,2WGIN@28216|Betaproteobacteria,1KPMM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
k59_539381_1	1249480.B649_07405	1.67e-124	375.0	COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,42MP9@68525|delta/epsilon subdivisions,2YMN8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Type I secretion system ATPase	-	-	-	ko:K12541	ko02010,map02010	M00330	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.109.3,3.A.1.109.4	-	-	ABC_membrane,ABC_tran
k59_1652978_1	1249480.B649_03270	2.69e-91	285.0	COG2199@1|root,COG3706@2|Bacteria,1NECV@1224|Proteobacteria,42PZK@68525|delta/epsilon subdivisions,2YT9R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_184216_1	709032.Sulku_1408	4.36e-63	208.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,42N7A@68525|delta/epsilon subdivisions,2YMRE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	lytic murein transglycosylase	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
k59_184216_2	709032.Sulku_1407	1.33e-11	60.5	COG0762@1|root,COG0762@2|Bacteria,1QDB9@1224|Proteobacteria,42VCU@68525|delta/epsilon subdivisions,2YQ8B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
k59_10346_1	2340.JV46_27340	1.32e-51	174.0	COG0679@1|root,COG0679@2|Bacteria,1N1X9@1224|Proteobacteria,1RMV0@1236|Gammaproteobacteria,1J5YV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
k59_184226_1	1408422.JHYF01000006_gene1059	3.12e-85	270.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,36DIS@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	yycG	-	2.7.13.3	ko:K07652	ko02020,map02020	M00459	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_8,PAS_9
k59_1711536_1	929558.SMGD1_0642	1.77e-245	695.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,42MRQ@68525|delta/epsilon subdivisions,2YMJY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1g
k59_1477189_1	159087.Daro_0129	4.8e-82	246.0	COG0500@1|root,COG2226@2|Bacteria,1MVSY@1224|Proteobacteria,2VMPA@28216|Betaproteobacteria,2KV25@206389|Rhodocyclales	206389|Rhodocyclales	Q	Methionine biosynthesis protein MetW	metW	-	-	-	-	-	-	-	-	-	-	-	MetW
k59_1477189_2	1304883.KI912532_gene658	4.63e-93	283.0	COG0477@1|root,COG2814@2|Bacteria,1MUZ8@1224|Proteobacteria,2VI8P@28216|Betaproteobacteria,2KVCT@206389|Rhodocyclales	206389|Rhodocyclales	EGP	Acetyl-coenzyme A transporter 1	ampG	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
k59_1358669_2	360106.CFF8240_1635	1.09e-66	224.0	COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,42MX8@68525|delta/epsilon subdivisions,2YN00@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	flaB	GO:0001539,GO:0005575,GO:0005576,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_IN,Flagellin_N
k59_711795_1	1537917.JU82_09780	1.64e-78	252.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42YH8@68525|delta/epsilon subdivisions,2YRAU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
k59_244065_1	709032.Sulku_1523	1.58e-69	217.0	COG1741@1|root,COG1741@2|Bacteria,1MVSW@1224|Proteobacteria,42T87@68525|delta/epsilon subdivisions,2YMZ0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
k59_1358695_1	1249480.B649_07400	1.88e-90	278.0	COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,42MCZ@68525|delta/epsilon subdivisions,2YNV4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	HlyD membrane-fusion protein of T1SS	-	-	-	ko:K12542	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	3.A.1.109.4,8.A.1	-	-	HlyD_3
k59_1536963_1	360910.BAV2623	1.16e-39	146.0	2DMHN@1|root,32RMC@2|Bacteria,1N2G3@1224|Proteobacteria,2VVUQ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	SGNH hydrolase-like domain, acetyltransferase AlgX	-	-	-	ko:K19295	-	-	-	-	ko00000	-	-	-	ALGX
k59_184270_1	457421.CBFG_05535	6.69e-05	49.7	COG0745@1|root,COG0745@2|Bacteria,1V3FX@1239|Firmicutes,24GC2@186801|Clostridia	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_127586_1	1249480.B649_05655	2.28e-48	161.0	COG4786@1|root,COG4786@2|Bacteria,1PZ24@1224|Proteobacteria,42NGI@68525|delta/epsilon subdivisions,2YNFE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar basal body	flgG2	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k59_127586_2	709032.Sulku_0984	2.75e-129	371.0	COG4786@1|root,COG4786@2|Bacteria,1MVMA@1224|Proteobacteria,42N3R@68525|delta/epsilon subdivisions,2YMWT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Belongs to the flagella basal body rod proteins family	flgG	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k59_656678_1	1408444.JHYC01000004_gene771	1.12e-10	69.7	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,1RPC6@1236|Gammaproteobacteria,1JCE8@118969|Legionellales	118969|Legionellales	L	Belongs to the helicase family. UvrD subfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
k59_419961_1	887327.HMPREF0476_1659	4.35e-08	55.5	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,2VH5Z@28216|Betaproteobacteria,2KPJP@206351|Neisseriales	206351|Neisseriales	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k59_1358720_1	1218084.BBJK01000020_gene2104	1.18e-13	71.6	COG0584@1|root,COG0584@2|Bacteria,1MU8H@1224|Proteobacteria,2VKF6@28216|Betaproteobacteria,1K1M5@119060|Burkholderiaceae	28216|Betaproteobacteria	C	glycerophosphoryl diester phosphodiesterase	ugpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
k59_1358720_2	159087.Daro_3304	3.87e-44	145.0	2EIBB@1|root,33C2R@2|Bacteria,1NETH@1224|Proteobacteria,2VXET@28216|Betaproteobacteria,2KXHM@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1770333_1	1537917.JU82_08725	1.07e-110	333.0	COG4972@1|root,COG4972@2|Bacteria,1QA6M@1224|Proteobacteria,42NDB@68525|delta/epsilon subdivisions,2YMP2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Pilus assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_543469_1	1249480.B649_00385	6.98e-144	415.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,42MS9@68525|delta/epsilon subdivisions,2YMBY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
k59_247537_1	1461694.ATO9_22480	7.35e-37	134.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,2TREV@28211|Alphaproteobacteria,2PC9J@252301|Oceanicola	28211|Alphaproteobacteria	M	UDP binding domain	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_247537_2	273526.SMDB11_0130	2.1e-18	81.6	COG0529@1|root,COG0529@2|Bacteria,1MX0D@1224|Proteobacteria,1RNWT@1236|Gammaproteobacteria,401TU@613|Serratia	1236|Gammaproteobacteria	F	Catalyzes the synthesis of activated sulfate	cysC	GO:0003674,GO:0003824,GO:0004020,GO:0005488,GO:0005515,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0042802,GO:0044237	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b2750,iB21_1397.B21_02565,iBWG_1329.BWG_2486,iEC042_1314.EC042_2944,iEC55989_1330.EC55989_3023,iECBD_1354.ECBD_0974,iECB_1328.ECB_02600,iECDH10B_1368.ECDH10B_2918,iECDH1ME8569_1439.ECDH1ME8569_2660,iECD_1391.ECD_02600,iECH74115_1262.ECH74115_4002,iECIAI1_1343.ECIAI1_2852,iECO111_1330.ECO111_3474,iECO26_1355.ECO26_3819,iECSE_1348.ECSE_3002,iECSP_1301.ECSP_3698,iECUMN_1333.ECUMN_3074,iECW_1372.ECW_m2956,iECs_1301.ECs3604,iEKO11_1354.EKO11_1019,iEcDH1_1363.EcDH1_0938,iEcE24377_1341.EcE24377A_3051,iEcHS_1320.EcHS_A2888,iEcSMS35_1347.EcSMS35_2876,iG2583_1286.G2583_3398,iJO1366.b2750,iJR904.b2750,iSBO_1134.SBO_2770,iSDY_1059.SDY_2949,iSFV_1184.SFV_2748,iSSON_1240.SSON_2898,iUMNK88_1353.UMNK88_3426,iWFL_1372.ECW_m2956,iY75_1357.Y75_RS14315,iZ_1308.Z4058	APS_kinase
k59_483797_1	1249480.B649_00290	8.22e-74	235.0	2DCNX@1|root,2ZESX@2|Bacteria,1QUV9@1224|Proteobacteria,43CMN@68525|delta/epsilon subdivisions,2YTEI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_774393_1	525898.Sdel_1999	2.1e-196	551.0	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,42QTE@68525|delta/epsilon subdivisions,2YR90@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_1656259_2	1537917.JU82_09130	3.37e-79	241.0	28WAS@1|root,2ZIB8@2|Bacteria,1NBB7@1224|Proteobacteria,42P2G@68525|delta/epsilon subdivisions,2YNQ5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_714168_1	90813.JQMT01000001_gene1819	6.08e-79	245.0	COG1469@1|root,COG1469@2|Bacteria,1MV1B@1224|Proteobacteria,1RNDY@1236|Gammaproteobacteria,461J3@72273|Thiotrichales	72273|Thiotrichales	S	Converts GTP to 7,8-dihydroneopterin triphosphate	folE2	-	3.5.4.16	ko:K09007	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GCHY-1
k59_835465_1	159087.Daro_0726	2.01e-63	217.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VI5B@28216|Betaproteobacteria,2KVAE@206389|Rhodocyclales	206389|Rhodocyclales	NT	Signal transducing histidine kinase, homodimeric domain	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
k59_1423054_1	709032.Sulku_1022	1.33e-85	270.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,42MVQ@68525|delta/epsilon subdivisions,2YMEZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CO	Thiol disulfide interchange protein	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin,Thioredoxin_2,Thioredoxin_7
k59_600193_1	1537917.JU82_08420	2.43e-140	410.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2YMA3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_1247804_1	709032.Sulku_2151	9.09e-134	385.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,42MCV@68525|delta/epsilon subdivisions,2YMK7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
k59_835491_2	1249480.B649_05400	1.19e-78	248.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,42MEQ@68525|delta/epsilon subdivisions,2YMGS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	COG0058 Glucan phosphorylase	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
k59_483868_1	159087.Daro_3473	3.33e-88	268.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,2VISR@28216|Betaproteobacteria,2KUDX@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
k59_1129763_1	1537917.JU82_11870	1.99e-106	318.0	COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,42N08@68525|delta/epsilon subdivisions,2YMRG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	folylpolyglutamate synthase	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
k59_1129763_2	1249480.B649_02600	1.6e-21	93.6	COG2199@1|root,COG3706@2|Bacteria,1MXAW@1224|Proteobacteria,42M6B@68525|delta/epsilon subdivisions,2YN3C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_1012862_1	1249480.B649_06315	2.1e-05	45.8	COG1055@1|root,COG1055@2|Bacteria,1MUX4@1224|Proteobacteria,42MHN@68525|delta/epsilon subdivisions,2YMYK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Involved in arsenical resistance. Thought to form the channel of an arsenite pump	arsB	-	-	ko:K03893	-	-	-	-	ko00000,ko02000	2.A.45.1,3.A.4.1	-	-	ArsB
k59_1012862_2	991905.SL003B_1329	1.43e-47	157.0	COG1393@1|root,COG1393@2|Bacteria,1MZ4Z@1224|Proteobacteria,2U70U@28211|Alphaproteobacteria,4BQCK@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	P	ArsC family	arsC	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
k59_543598_2	159087.Daro_3089	1.77e-99	302.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,2VHAY@28216|Betaproteobacteria,2KUIC@206389|Rhodocyclales	206389|Rhodocyclales	S	Peptidase M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_16,TPR_19
k59_1423116_1	1249480.B649_10620	1.49e-38	137.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,42ME1@68525|delta/epsilon subdivisions,2YMI9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
k59_1423116_2	1537917.JU82_01595	6.66e-203	567.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,42MG2@68525|delta/epsilon subdivisions,2YMJH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
k59_1714860_1	709032.Sulku_1100	4.48e-17	82.8	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,42RH7@68525|delta/epsilon subdivisions	1224|Proteobacteria	N	Flagellar motor protein	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
k59_953225_1	1123393.KB891316_gene1211	9.45e-35	124.0	COG1416@1|root,COG1416@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K09004	-	-	-	-	ko00000	-	-	-	DrsE
k59_953225_2	159087.Daro_1972	6.05e-17	80.9	COG3174@1|root,COG3174@2|Bacteria,1NDBI@1224|Proteobacteria,2VJ4P@28216|Betaproteobacteria,2KUDC@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of unknown function (DUF4010)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
k59_1834773_1	1123261.AXDW01000009_gene110	2.23e-83	265.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RMNZ@1236|Gammaproteobacteria,1X34U@135614|Xanthomonadales	135614|Xanthomonadales	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k59_660800_1	1165841.SULAR_08749	6.39e-99	304.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,42KZ7@68525|delta/epsilon subdivisions,2YMB1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iIT341.HP1532	GATase_6,SIS
k59_1834777_1	159087.Daro_3289	3.76e-37	129.0	COG0625@1|root,COG0625@2|Bacteria,1RHSK@1224|Proteobacteria,2VIJ5@28216|Betaproteobacteria,2KVP9@206389|Rhodocyclales	206389|Rhodocyclales	O	Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_N_3
k59_1834777_2	159087.Daro_3288	1.05e-181	514.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,2VI2T@28216|Betaproteobacteria,2KUAY@206389|Rhodocyclales	206389|Rhodocyclales	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ASL_C,Lyase_1
k59_715638_1	1132855.KB913035_gene1950	6.46e-15	72.8	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2VJI3@28216|Betaproteobacteria,2KMBQ@206350|Nitrosomonadales	206350|Nitrosomonadales	E	Belongs to the cysteine synthase cystathionine beta- synthase family	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_715638_2	1121035.AUCH01000002_gene1501	6.45e-19	87.4	COG1639@1|root,COG1639@2|Bacteria,1R4P9@1224|Proteobacteria,2WEED@28216|Betaproteobacteria	28216|Betaproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_1132186_2	709032.Sulku_1468	3.59e-79	241.0	COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,42QPB@68525|delta/epsilon subdivisions,2YNVC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Chemotaxis protein CheY	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_1250291_1	1300005.R9RHD9_9CAUD	1.56e-69	230.0	4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses  no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae	10744|Podoviridae	S	DNA polymerase family A	-	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360	-	-	-	-	-	-	-	-	-	-	-
k59_1364345_1	1537917.JU82_02885	3.12e-31	116.0	COG0810@1|root,COG0810@2|Bacteria,1NFMG@1224|Proteobacteria,42UAW@68525|delta/epsilon subdivisions,2YQER@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
k59_1482930_2	1132855.KB913035_gene2079	2.77e-89	271.0	COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,2VHAR@28216|Betaproteobacteria,2KKJB@206350|Nitrosomonadales	206350|Nitrosomonadales	G	Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides	nagZ	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
k59_1716823_1	159087.Daro_3638	1.65e-99	296.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,2VJJH@28216|Betaproteobacteria,2KUXU@206389|Rhodocyclales	206389|Rhodocyclales	K	Transcriptional regulator	-	-	-	ko:K21703	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k59_1599397_1	1304883.KI912532_gene2397	3.28e-129	376.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,2VH91@28216|Betaproteobacteria,2KUBJ@206389|Rhodocyclales	206389|Rhodocyclales	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
k59_1188338_1	159087.Daro_0556	3.53e-45	151.0	2BJ0W@1|root,32D9G@2|Bacteria,1PWYC@1224|Proteobacteria,2WCGA@28216|Betaproteobacteria,2KZ7D@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1188338_2	159087.Daro_0555	2.83e-82	249.0	COG0784@1|root,COG0784@2|Bacteria,1QWFW@1224|Proteobacteria,2VPCN@28216|Betaproteobacteria,2KVZ3@206389|Rhodocyclales	206389|Rhodocyclales	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
k59_1364353_2	1249480.B649_10570	2.74e-33	124.0	COG4968@1|root,COG4968@2|Bacteria,1R1K8@1224|Proteobacteria,43DAN@68525|delta/epsilon subdivisions,2YTHS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
k59_1015623_1	1249480.B649_02500	8.53e-93	272.0	COG0806@1|root,COG0806@2|Bacteria,1MYUH@1224|Proteobacteria,42SEN@68525|delta/epsilon subdivisions,2YPH6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
k59_1015623_2	1249480.B649_02505	3.32e-25	99.0	COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,42P8R@68525|delta/epsilon subdivisions,2YM7K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
k59_1716850_1	1304883.KI912532_gene3190	3.69e-96	283.0	COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,2VI2Y@28216|Betaproteobacteria,2KUV0@206389|Rhodocyclales	206389|Rhodocyclales	C	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodB	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
k59_602496_1	1123517.JOMR01000001_gene502	1.31e-58	200.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,1RNGW@1236|Gammaproteobacteria,45ZTE@72273|Thiotrichales	72273|Thiotrichales	M	Catalyzes cross-linking of the peptidoglycan cell wall at the division septum	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
k59_71084_1	1249480.B649_02260	1.11e-75	228.0	COG1214@1|root,COG1214@2|Bacteria,1Q1J6@1224|Proteobacteria,42TUF@68525|delta/epsilon subdivisions,2YQ3R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	COG1214 Inactive homolog of metal-dependent proteases	tsaB	-	-	-	-	-	-	-	-	-	-	-	-
k59_1599432_1	709032.Sulku_0605	8.9e-164	465.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,42MMY@68525|delta/epsilon subdivisions,2YMDM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	dihydropteroate synthase	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
k59_663282_1	1355368.JART01000008_gene1692	1.65e-38	136.0	COG1309@1|root,COG1309@2|Bacteria,1R52P@1224|Proteobacteria,42VHH@68525|delta/epsilon subdivisions,2YQ3V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Bacterial transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	TetR,TetR_N
k59_663282_2	498761.HM1_3059	1.72e-06	48.5	COG1826@1|root,COG1826@2|Bacteria	2|Bacteria	U	protein secretion	tatA	GO:0002790,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009977,GO:0009987,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032940,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03116,ko:K03425	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
k59_425126_1	1249480.B649_10410	5.18e-83	266.0	COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,42M8J@68525|delta/epsilon subdivisions,2YNGB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member	recD	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2,Viral_helicase1
k59_1775662_1	587753.EY04_16155	3.99e-78	248.0	COG0531@1|root,COG0531@2|Bacteria,1R4PP@1224|Proteobacteria,1RS90@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
k59_1483025_1	159087.Daro_3322	7.61e-59	199.0	COG0664@1|root,COG0664@2|Bacteria,1R9S2@1224|Proteobacteria,2VP8Y@28216|Betaproteobacteria,2KUHA@206389|Rhodocyclales	206389|Rhodocyclales	K	cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,PilJ,cNMP_binding
k59_1658514_1	1537917.JU82_00535	3.01e-124	365.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,42M6I@68525|delta/epsilon subdivisions,2YMNB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_602574_1	522306.CAP2UW1_2461	0.000118	44.7	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,2VKCK@28216|Betaproteobacteria,1KQVQ@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	M	Biotin-lipoyl like	mdtA_2	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
k59_602574_2	1304883.KI912532_gene1211	3.56e-109	342.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHZQ@28216|Betaproteobacteria,2KUT5@206389|Rhodocyclales	206389|Rhodocyclales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18303	-	M00642	-	-	ko00000,ko00002,ko01504,ko02000	2.A.6.2.17	-	-	ACR_tran
k59_15060_1	1537917.JU82_02085	9.87e-112	346.0	COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,1QUIU@1224|Proteobacteria,42M7I@68525|delta/epsilon subdivisions,2YMX0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG3893 inactivated superfamily I helicase	addB	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
k59_663390_1	269799.Gmet_2460	1.66e-18	88.6	COG3614@1|root,COG4251@1|root,COG3614@2|Bacteria,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_9,Phosphonate-bd,Protoglobin,Response_reg
k59_1837301_1	1209072.ALBT01000067_gene84	1.39e-64	223.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1FGUP@10|Cellvibrio	1236|Gammaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	CZB,DUF4118,EAL,GAF_2,GGDEF,PAS_3,PAS_4,PAS_9,Protoglobin
k59_1072083_1	1165841.SULAR_10239	1.52e-85	264.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,1MY9R@1224|Proteobacteria,42R1V@68525|delta/epsilon subdivisions	1224|Proteobacteria	K	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50,Peptidase_M50B
k59_1250463_1	114615.BRADO0596	6.11e-20	91.3	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,3JSR7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	MA20_09220	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
k59_546261_1	1163617.SCD_n01151	4.26e-89	277.0	28I8B@1|root,2Z8B5@2|Bacteria,1MUNM@1224|Proteobacteria,2VKHA@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Cytochrome c bacterial	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_cB
k59_425213_1	159087.Daro_0608	7.2e-71	229.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,2VJ86@28216|Betaproteobacteria,2KUHV@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
k59_134114_1	387093.SUN_0113	3.18e-117	338.0	COG2932@1|root,COG2932@2|Bacteria,1RIP6@1224|Proteobacteria,42RJG@68525|delta/epsilon subdivisions,2YP8P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	phage repressor	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24,Phage_CI_repr
k59_1543724_1	883126.HMPREF9710_01150	1.24e-92	281.0	COG1639@1|root,COG1639@2|Bacteria,1N7EN@1224|Proteobacteria,2VH2Y@28216|Betaproteobacteria,475J6@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_425220_1	1304885.AUEY01000069_gene1436	7.75e-68	216.0	COG0657@1|root,COG0657@2|Bacteria,1R4AU@1224|Proteobacteria,42XIQ@68525|delta/epsilon subdivisions,2WSR5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
k59_1304782_1	1195246.AGRI_06960	6.19e-57	187.0	COG0780@1|root,COG2904@1|root,COG0780@2|Bacteria,COG2904@2|Bacteria,1MW0M@1224|Proteobacteria,1RNXM@1236|Gammaproteobacteria,4650F@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016651,GO:0016657,GO:0018130,GO:0019438,GO:0033739,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.7.1.13	ko:K06879,ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	iSFV_1184.SFV_2663,iSF_1195.SF2807,iS_1188.S3002	QueF,QueF_N
k59_15097_1	717773.Thicy_0597	4.47e-52	171.0	COG2143@1|root,COG2143@2|Bacteria,1RB3S@1224|Proteobacteria,1S2A7@1236|Gammaproteobacteria,4628I@72273|Thiotrichales	72273|Thiotrichales	O	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_2
k59_1837346_1	1249480.B649_06145	6.33e-102	306.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,42NGG@68525|delta/epsilon subdivisions,2YN35@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Nucleotidyltransferase DNA polymerase involved in DNA repair	dinP	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
k59_1425805_1	159087.Daro_3408	6.33e-115	340.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,2VI1J@28216|Betaproteobacteria,2KU71@206389|Rhodocyclales	206389|Rhodocyclales	NU	type II secretion system protein	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
k59_486516_1	929558.SMGD1_1729	7.11e-80	261.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2YMKB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
k59_134129_1	1537917.JU82_03110	2.6e-125	360.0	COG0778@1|root,COG0778@2|Bacteria,1N95W@1224|Proteobacteria,42RYF@68525|delta/epsilon subdivisions,2YP3N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Nitroreductase	frxA	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_1837351_1	159087.Daro_0972	1.01e-86	281.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KVEE@206389|Rhodocyclales	206389|Rhodocyclales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,Response_reg
k59_663451_1	159087.Daro_0609	2.15e-83	263.0	COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,2VIV9@28216|Betaproteobacteria,2KV1S@206389|Rhodocyclales	206389|Rhodocyclales	D	peptidase, M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_306755_1	1304883.KI912532_gene3102	1.38e-118	359.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,2VH1K@28216|Betaproteobacteria,2KUE7@206389|Rhodocyclales	206389|Rhodocyclales	O	Belongs to the ClpA ClpB family	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_486530_1	1537917.JU82_04350	2.28e-61	205.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,42MYN@68525|delta/epsilon subdivisions,2YMXA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	molybdopterin oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin,Molydop_binding
k59_486530_2	709032.Sulku_1605	1.88e-53	178.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,42MHH@68525|delta/epsilon subdivisions,2YMRT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_776634_2	1208321.D104_15595	2.1e-42	148.0	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,1RNN8@1236|Gammaproteobacteria,1XI2H@135619|Oceanospirillales	135619|Oceanospirillales	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
k59_1072151_1	159087.Daro_1487	3.5e-107	324.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,2VKXT@28216|Betaproteobacteria,2KU7Y@206389|Rhodocyclales	206389|Rhodocyclales	KT	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF_2,HTH_8,Sigma54_activat
k59_1543770_1	1304883.KI912532_gene110	7.3e-151	453.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2VHCZ@28216|Betaproteobacteria,2KUGU@206389|Rhodocyclales	206389|Rhodocyclales	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
k59_1132443_1	1172190.M947_11225	1.97e-34	125.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,42RI5@68525|delta/epsilon subdivisions,2YP6Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0831	CoaE
k59_1132443_2	387093.SUN_2410	7.14e-114	331.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,42MRX@68525|delta/epsilon subdivisions,2YMC6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0566	DAP_epimerase
k59_1015878_1	34506.g1827	6.49e-34	134.0	COG0317@1|root,COG2265@1|root,KOG1157@2759|Eukaryota,KOG2187@2759|Eukaryota	2759|Eukaryota	J	S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity	-	-	2.7.6.5	ko:K00951,ko:K15332	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	HD_4,RelA_SpoT,TGS,TRAM,tRNA_U5-meth_tr
k59_1599602_1	999550.KI421507_gene2007	3.37e-20	91.3	COG2369@1|root,COG2369@2|Bacteria,1R40R@1224|Proteobacteria,2U3XS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	protein, homolog of phage Mu protein gp30	-	-	-	-	-	-	-	-	-	-	-	-	Phage_Mu_F
k59_602705_1	929558.SMGD1_0386	1.57e-40	154.0	COG0840@1|root,COG0840@2|Bacteria,1N5N4@1224|Proteobacteria,42RSG@68525|delta/epsilon subdivisions,2YRU6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
k59_189665_2	1249480.B649_08050	2.12e-54	172.0	2BSRI@1|root,32MUE@2|Bacteria,1Q3E8@1224|Proteobacteria,42X6B@68525|delta/epsilon subdivisions,2YQST@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_249942_1	159087.Daro_1302	4.87e-61	206.0	COG0582@1|root,COG0582@2|Bacteria,1PXUJ@1224|Proteobacteria,2VR8Z@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
k59_1015890_1	709032.Sulku_2360	3.1e-14	71.6	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,42NA4@68525|delta/epsilon subdivisions,2YN8R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EGP	transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
k59_1015890_2	1537917.JU82_02500	1.89e-198	556.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,42M5U@68525|delta/epsilon subdivisions,2YMQH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	molybdopterin biosynthesis	moeA2	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
k59_955708_1	395494.Galf_2448	2.02e-25	95.9	COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,2VSHZ@28216|Betaproteobacteria,44VX7@713636|Nitrosomonadales	28216|Betaproteobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
k59_955708_2	395494.Galf_2449	1.17e-49	158.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,2VU4W@28216|Betaproteobacteria,44VZX@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
k59_365694_1	1249480.B649_08625	3.36e-59	192.0	COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,42N94@68525|delta/epsilon subdivisions,2YMHM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
k59_365694_2	1172562.HCN_0119	7.52e-29	110.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,42PTV@68525|delta/epsilon subdivisions,2YNEP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
k59_1599633_1	1029823.AFIE01000028_gene3231	8.71e-139	413.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNSZ@1236|Gammaproteobacteria,3NIEG@468|Moraxellaceae	1236|Gammaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_189701_1	709032.Sulku_0036	1.12e-105	320.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42Q5F@68525|delta/epsilon subdivisions,2YPMR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	Cache_3-Cache_2,MCPsignal
k59_1132504_1	1537917.JU82_02990	3.47e-18	80.9	COG0704@1|root,COG0704@2|Bacteria,1Q5TJ@1224|Proteobacteria,42STN@68525|delta/epsilon subdivisions,2YPRM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	PhoU family	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
k59_1132504_2	1537917.JU82_02995	4.18e-54	179.0	COG0226@1|root,COG0226@2|Bacteria,1MUAZ@1224|Proteobacteria,42NM3@68525|delta/epsilon subdivisions,2YMMK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
k59_776693_1	1132855.KB913035_gene885	4.54e-36	144.0	COG0642@1|root,COG2203@1|root,COG3829@1|root,COG5002@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria,2KNFH@206350|Nitrosomonadales	206350|Nitrosomonadales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
k59_838068_1	709032.Sulku_2246	5.06e-58	189.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,42ME1@68525|delta/epsilon subdivisions,2YMI9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
k59_838068_3	563040.Saut_0445	3.71e-10	59.7	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42NES@68525|delta/epsilon subdivisions,2YNJ6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	COG1459 Type II secretory pathway, component PulF	-	-	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
k59_602765_1	159087.Daro_0770	3.99e-111	331.0	COG1157@1|root,COG1157@2|Bacteria,1MUH6@1224|Proteobacteria,2VHQ5@28216|Betaproteobacteria,2KUH3@206389|Rhodocyclales	206389|Rhodocyclales	NU	ATPase FliI YscN family	fliI	-	3.6.3.14	ko:K02412	ko02040,map02040	-	-	-	ko00000,ko00001,ko01000,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	ATP-synt_ab
k59_1837473_1	998088.B565_3726	1.58e-67	231.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,1Y3IW@135624|Aeromonadales	135624|Aeromonadales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_1658726_1	1249480.B649_04705	2.47e-86	283.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2YMRQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_249999_1	159087.Daro_0728	7.91e-83	267.0	COG0840@1|root,COG5000@1|root,COG0840@2|Bacteria,COG5000@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,2KU84@206389|Rhodocyclales	206389|Rhodocyclales	T	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,PAS_8
k59_427727_2	748247.AZKH_3349	3.87e-105	308.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,2VJ04@28216|Betaproteobacteria,2KW0Q@206389|Rhodocyclales	206389|Rhodocyclales	E	ATPases associated with a variety of cellular activities	-	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
k59_1429195_2	1249480.B649_03470	4.25e-68	212.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,42MFP@68525|delta/epsilon subdivisions,2YMI2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components	-	-	-	ko:K02034,ko:K12370	ko02010,ko02024,map02010,map02024	M00239,M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
k59_1135657_1	1537917.JU82_10945	2.96e-202	570.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2YNBN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k59_427741_1	1028800.RG540_CH13740	3.42e-74	246.0	COG0749@1|root,COG0749@2|Bacteria,1P27P@1224|Proteobacteria,2TVEI@28211|Alphaproteobacteria,4BIH2@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	DNA polymerase A domain	-	-	-	-	-	-	-	-	-	-	-	-	DNA_pol_A
k59_1191126_1	582402.Hbal_2896	4.62e-10	65.1	COG0842@1|root,COG0842@2|Bacteria,1NRMT@1224|Proteobacteria,2U293@28211|Alphaproteobacteria,43YWP@69657|Hyphomonadaceae	28211|Alphaproteobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
k59_1191126_2	882083.SacmaDRAFT_2728	5.09e-64	212.0	COG1131@1|root,COG1131@2|Bacteria,2IBJD@201174|Actinobacteria,4E1YQ@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC-type multidrug transport system, ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
k59_1191126_3	1203611.KB894543_gene1816	3.48e-20	90.9	COG0236@1|root,COG0304@1|root,COG0236@2|Bacteria,COG0304@2|Bacteria,4NE8K@976|Bacteroidetes,2FMAV@200643|Bacteroidia	976|Bacteroidetes	IQ	Belongs to the beta-ketoacyl-ACP synthases family	fabF2	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_1253891_1	420662.Mpe_A0745	1.98e-37	134.0	COG0583@1|root,COG0583@2|Bacteria,1N3DV@1224|Proteobacteria,2WEAQ@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_1253891_2	762376.AXYL_05873	1.02e-69	223.0	COG0477@1|root,COG2814@2|Bacteria,1MVHG@1224|Proteobacteria,2VHCU@28216|Betaproteobacteria,3T25Q@506|Alcaligenaceae	28216|Betaproteobacteria	EGP	Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_1485872_2	929558.SMGD1_0383	1.25e-39	139.0	COG1413@1|root,COG1413@2|Bacteria,1RIZR@1224|Proteobacteria	1224|Proteobacteria	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
k59_17528_1	305700.B447_03468	2.05e-163	477.0	COG1262@1|root,COG2227@1|root,COG1262@2|Bacteria,COG2227@2|Bacteria,1MUNC@1224|Proteobacteria,2VNKT@28216|Betaproteobacteria,2KVPF@206389|Rhodocyclales	206389|Rhodocyclales	H	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase,Methyltransf_25
k59_1778446_1	1165841.SULAR_05688	7.84e-15	69.3	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,42U00@68525|delta/epsilon subdivisions,2YPZU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	transport protein	tolR	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
k59_1778446_2	387093.SUN_1769	5.6e-65	203.0	COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,42PKF@68525|delta/epsilon subdivisions,2YNC3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	MotA TolQ ExbB proton channel family	tolQ	-	-	-	-	-	-	-	-	-	-	-	MotA_ExbB
k59_898331_1	159087.Daro_4088	1.76e-87	278.0	COG1629@1|root,COG4771@2|Bacteria,1MW7D@1224|Proteobacteria,2VIV2@28216|Betaproteobacteria,2KVXE@206389|Rhodocyclales	206389|Rhodocyclales	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_1429262_1	1430440.MGMSRv2_0986	6.04e-39	134.0	COG0745@1|root,COG0745@2|Bacteria,1RHDD@1224|Proteobacteria,2UA4W@28211|Alphaproteobacteria,2JT2H@204441|Rhodospirillales	204441|Rhodospirillales	KT	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
k59_192270_2	613026.HRAG_01609	1.14e-21	92.4	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,42M0Q@68525|delta/epsilon subdivisions,2YMXU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k59_779354_2	1537917.JU82_00735	9.95e-66	207.0	28M05@1|root,32SJ0@2|Bacteria,1N115@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1191175_2	1355368.JART01000002_gene2274	4.65e-22	94.4	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,42QAG@68525|delta/epsilon subdivisions,2YNQV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,Response_reg
k59_1547089_1	1249480.B649_06795	1.76e-67	209.0	2BV3K@1|root,3187I@2|Bacteria,1PZXK@1224|Proteobacteria,430TM@68525|delta/epsilon subdivisions,2YS1S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1547089_2	1537917.JU82_10475	8.32e-25	94.4	COG2014@1|root,COG2014@2|Bacteria	2|Bacteria	F	Putative heavy-metal chelation	-	-	-	-	-	-	-	-	-	-	-	-	DUF364
k59_1429282_1	1249480.B649_06005	2.37e-36	140.0	COG2202@1|root,COG2461@1|root,COG5001@1|root,COG2202@2|Bacteria,COG2461@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YN16@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	GGDEF EAL family protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_9
k59_368137_1	387093.SUN_0103	4.79e-86	275.0	COG1287@1|root,COG1287@2|Bacteria,1R8YG@1224|Proteobacteria,43BIB@68525|delta/epsilon subdivisions,2YT8Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Oligosaccharide transferase	-	-	2.4.99.18	ko:K07151	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	STT3
k59_137475_1	709032.Sulku_1412	3.79e-26	97.4	2AK4P@1|root,31AUI@2|Bacteria,1Q664@1224|Proteobacteria,42X10@68525|delta/epsilon subdivisions,2YQR8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_137475_2	709032.Sulku_1411	2.51e-112	327.0	COG0158@1|root,COG0158@2|Bacteria,1MW0E@1224|Proteobacteria,42NRA@68525|delta/epsilon subdivisions,2YMJC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1	fbp	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
k59_666906_1	1165841.SULAR_08809	2.78e-10	59.3	COG3637@1|root,COG3637@2|Bacteria,1NC11@1224|Proteobacteria	1224|Proteobacteria	M	COG3637 Opacity protein and related surface antigens	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OmpA_membrane
k59_1135756_1	631362.Thi970DRAFT_03235	4.33e-21	98.2	COG0642@1|root,COG0642@2|Bacteria,1NXDJ@1224|Proteobacteria,1T1YN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	signal transduction histidine kinase	-	-	2.7.13.3	ko:K07678	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_9,Response_reg,dCache_1
k59_427836_1	926569.ANT_02890	2.62e-62	198.0	COG1738@1|root,COG1738@2|Bacteria,2G6BZ@200795|Chloroflexi	200795|Chloroflexi	S	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
k59_841046_1	159087.Daro_1221	2.9e-84	262.0	COG1305@1|root,COG1305@2|Bacteria,1MY5V@1224|Proteobacteria,2VKGI@28216|Betaproteobacteria,2KW58@206389|Rhodocyclales	206389|Rhodocyclales	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
k59_841046_2	159087.Daro_1222	4.58e-64	207.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,2VH4P@28216|Betaproteobacteria,2KUNN@206389|Rhodocyclales	206389|Rhodocyclales	T	ATPase related to phosphate starvation-inducible protein PhoH	-	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
k59_779407_1	709032.Sulku_2263	1.86e-08	52.8	COG5591@1|root,COG5591@2|Bacteria	2|Bacteria	T	Peptidase propeptide and YPEB domain	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_2
k59_779407_2	1249480.B649_09330	8.14e-27	102.0	COG2184@1|root,COG2184@2|Bacteria,1RAVF@1224|Proteobacteria,42TM9@68525|delta/epsilon subdivisions,2YR7H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
k59_1429322_1	1249480.B649_10700	1.03e-133	415.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,43DMZ@68525|delta/epsilon subdivisions,2YMMS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_1840789_1	709032.Sulku_0634	2.31e-41	151.0	COG0739@1|root,COG0739@2|Bacteria,1N19D@1224|Proteobacteria,42SMK@68525|delta/epsilon subdivisions,2YTS0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_605783_1	1537917.JU82_08265	9.16e-119	350.0	COG0475@1|root,COG0475@2|Bacteria,1QTSD@1224|Proteobacteria,43BNR@68525|delta/epsilon subdivisions,2YT9V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	glutathione-regulated potassium-efflux system protein	kefB	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
k59_898416_1	1304883.KI912532_gene2979	2.75e-269	757.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,2VJ5Q@28216|Betaproteobacteria,2KV41@206389|Rhodocyclales	206389|Rhodocyclales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_1485972_1	1249480.B649_09005	4.68e-40	134.0	COG3323@1|root,COG3323@2|Bacteria,1MZF5@1224|Proteobacteria,42W00@68525|delta/epsilon subdivisions,2YS8D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1485972_3	1249480.B649_09015	3.91e-57	179.0	2AK8C@1|root,31AYM@2|Bacteria,1Q6J3@1224|Proteobacteria,43398@68525|delta/epsilon subdivisions,2YSRM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1719756_1	1249480.B649_07735	1.12e-97	300.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,42ME5@68525|delta/epsilon subdivisions,2YMKK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
k59_1191263_1	1537917.JU82_02845	1.43e-55	185.0	COG1271@1|root,COG2010@1|root,COG1271@2|Bacteria,COG2010@2|Bacteria,1RE9S@1224|Proteobacteria,43ANP@68525|delta/epsilon subdivisions,2YT2J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
k59_549879_1	640081.Dsui_0799	1.29e-47	165.0	COG0427@1|root,COG0427@2|Bacteria,1MUGE@1224|Proteobacteria,2VJUB@28216|Betaproteobacteria,2KVMY@206389|Rhodocyclales	206389|Rhodocyclales	C	acetyl-CoA hydrolase	cat1	-	2.8.3.18	ko:K18118	ko00020,ko00620,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00650,map01100,map01110,map01120,map01130,map01200	M00009,M00011	R10343	RC00012,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
k59_1547229_1	1249480.B649_02170	6.48e-116	341.0	COG1377@1|root,COG1377@2|Bacteria,1MUWI@1224|Proteobacteria,42NKR@68525|delta/epsilon subdivisions,2YMU1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhB	-	-	ko:K02401	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_2
k59_779498_1	1441629.PCH70_03890	4.38e-18	83.2	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,1RN4I@1236|Gammaproteobacteria,1Z62Q@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	GO:0000166,GO:0003674,GO:0003824,GO:0003856,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051287,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b3389,iBWG_1329.BWG_3080,iECDH10B_1368.ECDH10B_3564,iECDH1ME8569_1439.ECDH1ME8569_3268,iECNA114_1301.ECNA114_3486,iEcDH1_1363.EcDH1_0324,iJO1366.b3389,iJR904.b3389,iY75_1357.Y75_RS20275	DHQ_synthase
k59_779498_2	1168067.JAGP01000001_gene2062	2.24e-28	108.0	COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,1RPF6@1236|Gammaproteobacteria,460PM@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
k59_605854_1	1249480.B649_04850	2.13e-38	142.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,42MD4@68525|delta/epsilon subdivisions,2YNMI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	PFAM Helicase conserved C-terminal domain	hrpB	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
k59_605854_2	709032.Sulku_1555	7.64e-121	354.0	COG0810@1|root,COG0810@2|Bacteria,1PEYQ@1224|Proteobacteria,42WJI@68525|delta/epsilon subdivisions,2YQ9A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	TonB_2,TonB_C
k59_1719804_1	159087.Daro_0670	2.12e-125	369.0	COG1139@1|root,COG1139@2|Bacteria,1MV6J@1224|Proteobacteria,2VJ3Y@28216|Betaproteobacteria,2KU8D@206389|Rhodocyclales	206389|Rhodocyclales	C	Domain of unknown function (DUF3390)	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
k59_549923_1	159087.Daro_0023	2.33e-41	143.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,2VIVB@28216|Betaproteobacteria,2KUBC@206389|Rhodocyclales	206389|Rhodocyclales	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
k59_549923_2	159087.Daro_0022	1.84e-89	270.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,2VIS2@28216|Betaproteobacteria,2KVNV@206389|Rhodocyclales	206389|Rhodocyclales	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
k59_17662_2	596320.NEIFL0001_0528	5.56e-148	440.0	COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,2VHBQ@28216|Betaproteobacteria,2KPMW@206351|Neisseriales	206351|Neisseriales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_309109_1	1537917.JU82_01405	2.68e-74	234.0	COG2199@1|root,COG3706@2|Bacteria,1NC00@1224|Proteobacteria,43DI1@68525|delta/epsilon subdivisions,2YTIQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	diguanylate cyclase	-	-	2.7.7.65	ko:K13590	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF
k59_1719823_1	575788.VS_II0321	9.49e-74	238.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1XSNZ@135623|Vibrionales	135623|Vibrionales	F	DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k59_1840913_1	697282.Mettu_1938	1.62e-05	45.4	COG2703@1|root,COG2703@2|Bacteria,1PGPP@1224|Proteobacteria,1RX1T@1236|Gammaproteobacteria,1XGPW@135618|Methylococcales	135618|Methylococcales	P	PFAM Haemerythrin HHE cation-binding motif	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
k59_1840913_2	1304883.KI912532_gene2105	4.3e-64	198.0	COG2847@1|root,COG2847@2|Bacteria,1MZ3M@1224|Proteobacteria,2VTY7@28216|Betaproteobacteria,2KWMU@206389|Rhodocyclales	206389|Rhodocyclales	S	Copper chaperone PCu(A)C	-	-	-	ko:K09796	-	-	-	-	ko00000,ko03110	-	-	-	PCuAC
k59_1778632_1	640081.Dsui_2856	1.58e-26	114.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VJA5@28216|Betaproteobacteria,2KVKM@206389|Rhodocyclales	206389|Rhodocyclales	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
k59_958802_1	709032.Sulku_1616	6.82e-95	289.0	COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,42MQ6@68525|delta/epsilon subdivisions,2YNPN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DNA photolyase family	phrB	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
k59_1719840_1	225937.HP15_1553	3.62e-79	240.0	COG3806@1|root,COG3806@2|Bacteria,1R52I@1224|Proteobacteria,1RNI5@1236|Gammaproteobacteria,467KI@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	Anti-ECFsigma factor ChrR	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_7
k59_1429486_2	709032.Sulku_1880	4.06e-43	149.0	COG3218@1|root,COG3218@2|Bacteria,1NNSH@1224|Proteobacteria,42X3M@68525|delta/epsilon subdivisions,2YQQ8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	transport system auxiliary component	-	-	-	ko:K18480	-	M00669	-	-	ko00000,ko00002,ko02000	3.A.1.27.1	-	-	ABC_trans_aux
k59_806717_1	709032.Sulku_0794	2.46e-16	78.2	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42UBD@68525|delta/epsilon subdivisions,2YRGP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	7TM diverse intracellular signalling	-	-	-	ko:K20971	ko02025,map02025	-	-	-	ko00000,ko00001,ko01001,ko02022	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c
k59_806717_2	709032.Sulku_0795	7.36e-77	234.0	COG0476@1|root,COG0476@2|Bacteria,1P1FY@1224|Proteobacteria,42PK6@68525|delta/epsilon subdivisions,2YNCI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	involved in molybdopterin and thiamine biosynthesis family 2	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
k59_921336_1	159087.Daro_4007	2.88e-82	248.0	COG1802@1|root,COG1802@2|Bacteria,1MWG2@1224|Proteobacteria,2VN1E@28216|Betaproteobacteria,2KUEP@206389|Rhodocyclales	206389|Rhodocyclales	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
k59_1329747_1	1249480.B649_05125	1.12e-134	387.0	COG0715@1|root,COG0715@2|Bacteria,1MWUA@1224|Proteobacteria	1224|Proteobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,SBP_bac_3
k59_1329747_2	1249480.B649_05130	5.05e-21	89.0	COG0600@1|root,COG0600@2|Bacteria,1MWS0@1224|Proteobacteria,42NC9@68525|delta/epsilon subdivisions,2YMSM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	ABC transporter permease	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
k59_1626208_1	709032.Sulku_0661	8.54e-155	458.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,42MN5@68525|delta/epsilon subdivisions,2YN0Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	DUF294,GlnD_UR_UTase,HD,NTP_transf_2
k59_1574394_2	292564.Cyagr_1969	6.72e-22	90.9	COG3548@1|root,COG3548@2|Bacteria,1GKP8@1117|Cyanobacteria,22TD7@167375|Cyanobium	1117|Cyanobacteria	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
k59_1214483_1	159087.Daro_3899	1.68e-85	253.0	COG0745@1|root,COG0745@2|Bacteria,1RDYB@1224|Proteobacteria,2VR2Q@28216|Betaproteobacteria,2KWB2@206389|Rhodocyclales	206389|Rhodocyclales	T	cheY-homologous receiver domain	pilG	-	-	ko:K02657	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
k59_1214483_2	159087.Daro_3898	4.12e-57	178.0	COG0745@1|root,COG0745@2|Bacteria,1RI9T@1224|Proteobacteria,2VSSD@28216|Betaproteobacteria,2KWTI@206389|Rhodocyclales	206389|Rhodocyclales	T	response regulator receiver	pilH	-	-	ko:K02658	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
k59_161448_1	159087.Daro_3657	2.62e-48	162.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,2VJN0@28216|Betaproteobacteria,2KV6F@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
k59_161448_2	159087.Daro_3656	2.03e-18	81.6	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,2VH15@28216|Betaproteobacteria,2KUK6@206389|Rhodocyclales	206389|Rhodocyclales	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
k59_694580_1	159087.Daro_0666	1.14e-119	362.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,2VIYB@28216|Betaproteobacteria,2KVTV@206389|Rhodocyclales	206389|Rhodocyclales	C	Malic enzyme	-	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
k59_388749_1	399795.CtesDRAFT_PD0024	3.46e-74	234.0	COG3039@1|root,COG3039@2|Bacteria,1MUVI@1224|Proteobacteria,2VK9J@28216|Betaproteobacteria,4AB5J@80864|Comamonadaceae	28216|Betaproteobacteria	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
k59_1626258_1	871968.DESME_13845	2.5e-18	88.6	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia,260DV@186807|Peptococcaceae	186801|Clostridia	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_1744392_1	1249480.B649_07245	9.57e-115	331.0	COG0586@1|root,COG0586@2|Bacteria,1NBBA@1224|Proteobacteria,42MFR@68525|delta/epsilon subdivisions,2YMZ2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	membrane-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
k59_1626263_1	1537917.JU82_01520	1.01e-153	441.0	COG2710@1|root,COG2710@2|Bacteria,1MWAJ@1224|Proteobacteria,42M5T@68525|delta/epsilon subdivisions,2YNN6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	cofactor biosynthesis protein NifE	-	-	-	ko:K02587	-	-	-	-	ko00000	-	-	-	Oxidored_nitro
k59_388761_1	749222.Nitsa_0619	1.42e-79	251.0	COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,42MPV@68525|delta/epsilon subdivisions,2YNN7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
k59_1626302_1	90813.JQMT01000001_gene177	1.74e-27	110.0	COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,1RSHS@1236|Gammaproteobacteria,460T0@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	GO:0003674,GO:0003824,GO:0004141,GO:0016874,GO:0016879,GO:0016882	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
k59_1626302_2	1439940.BAY1663_04875	1.67e-11	64.3	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,1RSY6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Reversible hydration of carbon dioxide	can	GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008270,GO:0015976,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	iSBO_1134.SBO_0115,iSbBS512_1146.SbBS512_E0119	Pro_CA
k59_273630_1	159087.Daro_1515	6.36e-108	320.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,2VNE4@28216|Betaproteobacteria,2KVVM@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine	nifS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
k59_1329896_1	709032.Sulku_1890	4.26e-88	281.0	COG0457@1|root,COG4783@1|root,COG0457@2|Bacteria,COG4783@2|Bacteria,1QV15@1224|Proteobacteria,42NKI@68525|delta/epsilon subdivisions,2YMKG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	COG0457 FOG TPR repeat	pflB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_6,TPR_8
k59_37041_1	572480.Arnit_2572	8.7e-13	67.4	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,42MWH@68525|delta/epsilon subdivisions,2YMPE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	epimerase dehydratase family	-	-	5.1.3.2,5.1.3.6	ko:K01784,ko:K08679	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R01385,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
k59_37041_2	367737.Abu_0661	5.51e-103	308.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,42M4F@68525|delta/epsilon subdivisions,2YMAG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	-	ko:K02474	ko00520,map00520	-	R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_736411_2	1165841.SULAR_08197	5.87e-114	344.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,42M20@68525|delta/epsilon subdivisions,2YMDG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
k59_1214618_1	497321.C664_09450	4.52e-56	191.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2VHBY@28216|Betaproteobacteria,2KUED@206389|Rhodocyclales	206389|Rhodocyclales	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_1214618_2	1276756.AUEX01000004_gene2489	5.67e-36	132.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,2VIBU@28216|Betaproteobacteria,4AC56@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
k59_388847_2	317025.Tcr_2100	2.29e-36	127.0	2B9KW@1|root,322Z5@2|Bacteria,1RJJB@1224|Proteobacteria,1SAPM@1236|Gammaproteobacteria,461G8@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_93829_1	709032.Sulku_0580	8.48e-144	418.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,42M6T@68525|delta/epsilon subdivisions,2YMJD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
k59_921575_1	553385.JEMF01000105_gene2262	6.47e-54	192.0	COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,1S48Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
k59_93844_1	1323663.AROI01000020_gene710	7.85e-19	84.3	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,1RPSV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k59_93844_2	90814.KL370891_gene1789	8.36e-43	152.0	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,1T03U@1236|Gammaproteobacteria,45ZMM@72273|Thiotrichales	72273|Thiotrichales	F	TIGRFAM dihydroorotase, multifunctional complex type	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
k59_631973_2	709032.Sulku_2242	4.46e-28	115.0	COG0457@1|root,COG0457@2|Bacteria,1Q60C@1224|Proteobacteria,42X29@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Anaphase-promoting complex, cyclosome, subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC3
k59_1214655_1	1173029.JH980292_gene290	1.39e-33	123.0	COG1682@1|root,COG1682@2|Bacteria,1G23R@1117|Cyanobacteria,1H8WK@1150|Oscillatoriales	1117|Cyanobacteria	GM	COG1682 ABC-type polysaccharide polyol phosphate export systems, permease component	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
k59_1391569_1	1165841.SULAR_07300	1.65e-53	186.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,42NN7@68525|delta/epsilon subdivisions,2YMKH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
k59_1391569_2	1165841.SULAR_07295	9.44e-33	126.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,42MFA@68525|delta/epsilon subdivisions,2YMUE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
k59_1507873_1	387093.SUN_1351	2.31e-125	383.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,42N4X@68525|delta/epsilon subdivisions,2YMTD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Belongs to the FtsK SpoIIIE SftA family	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
k59_1803159_2	1249480.B649_06975	7.63e-60	186.0	2E67S@1|root,32Q79@2|Bacteria,1N05A@1224|Proteobacteria,42X30@68525|delta/epsilon subdivisions,2YQVD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Nitrogen fixation protein NifW	-	-	-	ko:K02595	-	-	-	-	ko00000	-	-	-	NifW
k59_1578361_1	1165841.SULAR_08452	9.38e-169	486.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,42M3S@68525|delta/epsilon subdivisions,2YN4P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	GTP-binding protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
k59_163923_1	717774.Marme_2878	3.46e-59	191.0	COG0454@1|root,COG0454@2|Bacteria,1MVVG@1224|Proteobacteria,1RQ5J@1236|Gammaproteobacteria,1XPBK@135619|Oceanospirillales	135619|Oceanospirillales	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k59_1051252_1	387093.SUN_1816	1.29e-122	367.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2YN8I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Abc transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
k59_1629329_1	1249480.B649_05930	3.84e-21	87.8	COG1934@1|root,COG1934@2|Bacteria,1NJS7@1224|Proteobacteria,42SEJ@68525|delta/epsilon subdivisions,2YPFN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Lipopolysaccharide transport periplasmic protein lpta	lptA	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA
k59_1629329_3	709032.Sulku_1430	3.91e-70	214.0	COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,42SN2@68525|delta/epsilon subdivisions,2YPEC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase	kdsC	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
k59_1747922_1	1249480.B649_04845	1.57e-118	340.0	COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,42QZJ@68525|delta/epsilon subdivisions,2YNXZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
k59_96574_1	1502770.JQMG01000001_gene2107	7.01e-113	332.0	COG4783@1|root,COG4783@2|Bacteria,1R84W@1224|Proteobacteria,2VIBK@28216|Betaproteobacteria,2KKQH@206350|Nitrosomonadales	206350|Nitrosomonadales	S	PFAM peptidase M48 Ste24p	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
k59_1333428_1	563040.Saut_1309	3.2e-195	556.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,42M4S@68525|delta/epsilon subdivisions,2YM8Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	-	-	1.12.5.1	ko:K05922	-	-	-	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
k59_1283646_2	395494.Galf_1688	5.74e-86	261.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,2VIVV@28216|Betaproteobacteria,44VC9@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_634724_1	159087.Daro_2402	3.19e-107	319.0	COG0381@1|root,COG0381@2|Bacteria,1QUYI@1224|Proteobacteria,2WFJ1@28216|Betaproteobacteria,2KVGN@206389|Rhodocyclales	206389|Rhodocyclales	G	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	mnaA	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
k59_96628_1	159087.Daro_0981	1.32e-42	142.0	COG1941@1|root,COG1941@2|Bacteria,1NS0E@1224|Proteobacteria,2VJH8@28216|Betaproteobacteria,2KVSW@206389|Rhodocyclales	206389|Rhodocyclales	C	NADH ubiquinone oxidoreductase, 20	hoxY	-	1.12.1.2	ko:K18007	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_q6
k59_96628_2	159087.Daro_0982	6.08e-59	194.0	COG3259@1|root,COG3259@2|Bacteria,1QUQ7@1224|Proteobacteria,2VJT0@28216|Betaproteobacteria,2KVAX@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	hoxH	-	1.12.1.2	ko:K00436	-	-	R00700	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
k59_164006_1	1537917.JU82_01670	1.4e-177	532.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,43DMZ@68525|delta/epsilon subdivisions,2YMMS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_989307_1	1304883.KI912532_gene1267	3.52e-111	330.0	COG2821@1|root,COG2821@2|Bacteria,1MXD4@1224|Proteobacteria,2VHBF@28216|Betaproteobacteria,2KV14@206389|Rhodocyclales	206389|Rhodocyclales	M	Membrane-bound lytic murein transglycosylase	mltA	-	-	ko:K08304	-	-	-	-	ko00000,ko01000,ko01011	-	GH102	-	3D,MltA
k59_516644_1	709032.Sulku_0659	8.48e-113	341.0	COG2199@1|root,COG3706@2|Bacteria,1NECV@1224|Proteobacteria,42PZK@68525|delta/epsilon subdivisions,2YT9R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_516644_2	1249480.B649_03265	1.07e-186	536.0	COG2199@1|root,COG2199@2|Bacteria,1QTZT@1224|Proteobacteria,43E8E@68525|delta/epsilon subdivisions,2YN2B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_164060_1	1165841.SULAR_02328	1.63e-47	164.0	COG0715@1|root,COG0715@2|Bacteria,1NV0U@1224|Proteobacteria,42SS6@68525|delta/epsilon subdivisions,2YPMU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	-
k59_96702_1	1537917.JU82_02460	1.38e-61	197.0	COG0760@1|root,COG0760@2|Bacteria,1N20M@1224|Proteobacteria,42SXW@68525|delta/epsilon subdivisions,2YPHS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase_2,SurA_N,SurA_N_3
k59_925197_1	387093.SUN_2152	2.88e-125	377.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,42NN7@68525|delta/epsilon subdivisions,2YMKH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
k59_453568_1	1249480.B649_04745	3.36e-123	357.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,42N3M@68525|delta/epsilon subdivisions,2YMHR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dusB	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
k59_453568_2	1249480.B649_04760	6.97e-29	107.0	COG0790@1|root,COG0790@2|Bacteria	2|Bacteria	S	beta-lactamase activity	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
k59_516720_1	411684.HPDFL43_01665	6.89e-100	304.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2TRIQ@28211|Alphaproteobacteria,43N46@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
k59_1459726_1	709032.Sulku_1770	2.43e-101	296.0	COG1309@1|root,COG1309@2|Bacteria,1PFKA@1224|Proteobacteria,43DPT@68525|delta/epsilon subdivisions,2YRXX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
k59_1510693_2	1537917.JU82_00560	9.95e-98	287.0	COG0421@1|root,COG0421@2|Bacteria,1PD55@1224|Proteobacteria,42UAB@68525|delta/epsilon subdivisions,2YPTY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synt_N,Spermine_synth
k59_1510693_3	1249480.B649_00435	5.92e-33	119.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,42RI5@68525|delta/epsilon subdivisions,2YP6Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0831	CoaE
k59_516727_1	1165841.SULAR_07460	3.45e-104	312.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,42MQ3@68525|delta/epsilon subdivisions,2YMPC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
k59_634867_1	1304883.KI912532_gene33	1.43e-25	105.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria,2KUIP@206389|Rhodocyclales	206389|Rhodocyclales	T	Histidine Phosphotransfer domain	-	-	2.7.13.1	ko:K05962	-	-	-	-	ko00000,ko01000	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,Response_reg
k59_634867_2	159087.Daro_0936	3.45e-91	272.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,2VJC3@28216|Betaproteobacteria,2KUZX@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
k59_221101_1	395493.BegalDRAFT_0278	1.89e-90	282.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RMTB@1236|Gammaproteobacteria,4600M@72273|Thiotrichales	72273|Thiotrichales	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_1283776_1	159087.Daro_3895	1.09e-96	318.0	COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VJSZ@28216|Betaproteobacteria,2KUBP@206389|Rhodocyclales	206389|Rhodocyclales	KNT	COG0643 Chemotaxis protein histidine kinase and related kinases	pilL	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,HATPase_c,Hpt,Response_reg
k59_96801_1	644968.DFW101_1459	6.65e-23	102.0	COG2199@1|root,COG4753@1|root,COG3706@2|Bacteria,COG4753@2|Bacteria,1R7HC@1224|Proteobacteria,42QQC@68525|delta/epsilon subdivisions,2X5E7@28221|Deltaproteobacteria,2M8TN@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	TIGRFAM Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
k59_96801_2	572480.Arnit_0391	2.14e-07	52.8	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42NFR@68525|delta/epsilon subdivisions,2YMBV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg
k59_863882_1	709032.Sulku_0019	1.97e-78	253.0	COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,42RCJ@68525|delta/epsilon subdivisions,2YNX9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG4775 Outer membrane protein protective antigen OMA87	-	-	-	ko:K07278	-	-	-	-	ko00000,ko02000	1.B.33.2.4	-	-	Bac_surface_Ag,POTRA
k59_1164369_1	159087.Daro_0219	7.09e-13	66.6	COG0640@1|root,COG0640@2|Bacteria,1RBZC@1224|Proteobacteria,2VR13@28216|Betaproteobacteria,2KW3M@206389|Rhodocyclales	206389|Rhodocyclales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1164369_2	338969.Rfer_2215	2.16e-58	195.0	COG2719@1|root,COG2719@2|Bacteria,1MW6U@1224|Proteobacteria,2VHJ7@28216|Betaproteobacteria,4ABG5@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM SpoVR family protein	spoVR2	-	-	ko:K06415	-	-	-	-	ko00000	-	-	-	SpoVR
k59_1803386_1	1249480.B649_05345	8.27e-56	194.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,42WJ0@68525|delta/epsilon subdivisions,2YQJR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	PFAM TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_516773_1	709032.Sulku_0602	8.37e-127	370.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,42NDT@68525|delta/epsilon subdivisions,2YMIS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
k59_1217829_1	1123367.C666_03165	4.15e-56	179.0	COG4704@1|root,COG4704@2|Bacteria,1N6RE@1224|Proteobacteria,2VV4P@28216|Betaproteobacteria,2KZ1B@206389|Rhodocyclales	206389|Rhodocyclales	S	Uncharacterized protein conserved in bacteria (DUF2141)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2141
k59_1869739_1	1249480.B649_07335	1.29e-64	211.0	COG3400@1|root,COG3400@2|Bacteria,1N5T1@1224|Proteobacteria,42M0B@68525|delta/epsilon subdivisions,2YMCG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	domain protein	-	-	-	ko:K09944	-	-	-	-	ko00000	-	-	-	TrkA_C
k59_1869739_2	1537917.JU82_06645	1.2e-20	89.7	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,42MW5@68525|delta/epsilon subdivisions,2YN4M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0283	DHQ_synthase
k59_634938_1	563040.Saut_2104	1.42e-05	46.2	COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,42MIP@68525|delta/epsilon subdivisions,2YMPW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
k59_634938_2	1249480.B649_11665	1.89e-84	251.0	COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,42SIR@68525|delta/epsilon subdivisions,2YP9V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
k59_1217876_1	159087.Daro_0853	1.83e-133	387.0	COG1752@1|root,COG1752@2|Bacteria,1PIHH@1224|Proteobacteria,2VHKX@28216|Betaproteobacteria,2KUYE@206389|Rhodocyclales	206389|Rhodocyclales	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
k59_331212_1	153948.NAL212_0013	1.05e-104	307.0	COG3676@1|root,COG3676@2|Bacteria,1QTF7@1224|Proteobacteria,2VSUV@28216|Betaproteobacteria	28216|Betaproteobacteria	L	ISXO2-like transposase domain	-	-	-	ko:K07488	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS1595
k59_4029_2	709032.Sulku_0118	1.92e-69	215.0	COG3248@1|root,COG3248@2|Bacteria,1RC26@1224|Proteobacteria,42V71@68525|delta/epsilon subdivisions,2YRU5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Nucleoside-specific channel-forming protein, Tsx	-	-	-	-	-	-	-	-	-	-	-	-	Channel_Tsx
k59_61642_1	1249480.B649_01495	3.16e-66	215.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,42M0I@68525|delta/epsilon subdivisions,2YMV0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
k59_61642_2	387093.SUN_1898	5.65e-07	50.4	COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,42KZP@68525|delta/epsilon subdivisions,2YMBP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG1055 Na H antiporter NhaD and related arsenite	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
k59_1001116_1	1121035.AUCH01000009_gene918	0.000199	43.1	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,2VIYT@28216|Betaproteobacteria,2KUQH@206389|Rhodocyclales	206389|Rhodocyclales	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
k59_1001116_2	159087.Daro_3507	1.86e-96	281.0	COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,2VRGP@28216|Betaproteobacteria,2KWNN@206389|Rhodocyclales	206389|Rhodocyclales	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
k59_1059338_2	1537917.JU82_09880	1.36e-93	274.0	COG0494@1|root,COG0494@2|Bacteria,1RDGJ@1224|Proteobacteria,42RGH@68525|delta/epsilon subdivisions,2YP5E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage	nudH	-	-	ko:K08311	ko03018,map03018	-	R10816	RC00002	ko00000,ko00001,ko01000,ko03019	-	-	-	NUDIX
k59_1529916_1	935845.JADQ01000001_gene1163	5.88e-15	75.1	COG0714@1|root,COG0714@2|Bacteria,1TPKR@1239|Firmicutes,4HA0T@91061|Bacilli,26S8N@186822|Paenibacillaceae	91061|Bacilli	S	magnesium chelatase	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_6499_1	1537917.JU82_04350	7.66e-80	254.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,42MYN@68525|delta/epsilon subdivisions,2YMXA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	molybdopterin oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin,Molydop_binding
k59_885526_2	1249480.B649_02380	6.3e-64	196.0	29NSE@1|root,309QF@2|Bacteria,1QT0N@1224|Proteobacteria,42TIY@68525|delta/epsilon subdivisions,2YP79@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_827295_1	387092.NIS_1776	9.05e-42	147.0	COG1522@1|root,COG1522@2|Bacteria,1NVYY@1224|Proteobacteria,43B09@68525|delta/epsilon subdivisions,2YMJI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_827295_2	944547.ABLL_0494	7.97e-07	50.8	COG0007@1|root,COG0007@2|Bacteria,1MUI0@1224|Proteobacteria,42MCB@68525|delta/epsilon subdivisions,2YNRA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme	-	-	2.1.1.107,4.2.1.75	ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	TP_methylase
k59_1238644_1	90814.KL370891_gene1812	1.6e-46	169.0	COG2199@1|root,COG3706@2|Bacteria,1RDI8@1224|Proteobacteria,1S436@1236|Gammaproteobacteria,462K0@72273|Thiotrichales	72273|Thiotrichales	T	Response regulator receiver modulated diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_3
k59_1590207_1	1537917.JU82_00270	1.3e-85	263.0	COG0477@1|root,COG2814@2|Bacteria,1MVKJ@1224|Proteobacteria,43DA9@68525|delta/epsilon subdivisions,2YSK6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_1590207_2	709032.Sulku_1825	7.8e-80	239.0	COG4681@1|root,COG4681@2|Bacteria,1RDR9@1224|Proteobacteria,42QRY@68525|delta/epsilon subdivisions,2YRU2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	YaeQ	-	-	-	-	-	-	-	-	-	-	-	-	YaeQ
k59_885549_1	709032.Sulku_1906	1.23e-55	191.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42SS2@68525|delta/epsilon subdivisions,2YRAM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	CZB,MCPsignal
k59_885549_2	1449345.JHWC01000006_gene946	2.28e-06	49.7	COG3562@1|root,COG3562@2|Bacteria,1MUZT@1224|Proteobacteria,42P5Z@68525|delta/epsilon subdivisions,2YMNP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Capsule polysaccharide biosynthesis protein	kpsS	-	-	ko:K07265	-	-	-	-	ko00000	-	-	-	Capsule_synth
k59_827310_2	1537917.JU82_09710	1.6e-37	131.0	COG3381@1|root,COG3381@2|Bacteria,1N4MX@1224|Proteobacteria,42RVB@68525|delta/epsilon subdivisions,2YP5X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	component of anaerobic	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_del
k59_708578_1	1249480.B649_05400	1.41e-96	299.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,42MEQ@68525|delta/epsilon subdivisions,2YMGS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	COG0058 Glucan phosphorylase	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
k59_1003477_2	709032.Sulku_1160	2.68e-195	551.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,42MXN@68525|delta/epsilon subdivisions,2YN93@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EH	anthranilate synthase component	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP1282	Anth_synt_I_N,Chorismate_bind
k59_415851_1	580332.Slit_0903	6.27e-102	307.0	COG2710@1|root,COG2710@2|Bacteria,1MWAJ@1224|Proteobacteria,2VJ11@28216|Betaproteobacteria,44WB6@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Nitrogenase component 1 type Oxidoreductase	nifE	-	-	ko:K02587	-	-	-	-	ko00000	-	-	-	Oxidored_nitro
k59_944782_1	709032.Sulku_1949	3.27e-154	440.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,42M27@68525|delta/epsilon subdivisions,2YNWH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
k59_1061259_1	1249480.B649_01685	9.6e-73	226.0	COG1639@1|root,COG1639@2|Bacteria,1Q1C5@1224|Proteobacteria,42T98@68525|delta/epsilon subdivisions,2YPNT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_827363_1	1123487.KB892846_gene470	2.09e-22	100.0	COG0745@1|root,COG0745@2|Bacteria,1R52E@1224|Proteobacteria,2VZQH@28216|Betaproteobacteria,2KWDF@206389|Rhodocyclales	206389|Rhodocyclales	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_122593_1	926550.CLDAP_40720	1.72e-30	125.0	COG3497@1|root,COG3497@2|Bacteria,2G7YJ@200795|Chloroflexi	200795|Chloroflexi	S	PFAM tail sheath protein	-	-	-	ko:K06907	-	-	-	-	ko00000	-	-	-	Phage_sheath_1,Phage_sheath_1C
k59_708616_1	159087.Daro_1495	2.02e-108	322.0	COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,2VKUY@28216|Betaproteobacteria,2KVVJ@206389|Rhodocyclales	206389|Rhodocyclales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
k59_122606_1	709032.Sulku_2334	9.41e-112	334.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42MFK@68525|delta/epsilon subdivisions,2YN87@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Abc transporter	nikZ	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k59_708621_1	709032.Sulku_0719	4.18e-86	259.0	COG3267@1|root,COG3267@2|Bacteria,1QUIM@1224|Proteobacteria,42NAC@68525|delta/epsilon subdivisions,2YNHY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	ATPase (AAA	-	-	4.3.3.7	ko:K01714,ko:K12283	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	AAA_22
k59_1532416_1	1537917.JU82_03070	7.5e-39	137.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,42M8N@68525|delta/epsilon subdivisions,2YMFN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	hprA	-	1.1.1.29	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	M00346	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
k59_1532416_2	1537917.JU82_10490	2.36e-37	135.0	COG0810@1|root,COG0810@2|Bacteria,1PEYQ@1224|Proteobacteria,42WJI@68525|delta/epsilon subdivisions,2YQ9A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	TonB_2,TonB_C
k59_1238752_1	159087.Daro_2015	7.84e-112	328.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,2VI2A@28216|Betaproteobacteria,2KUAG@206389|Rhodocyclales	206389|Rhodocyclales	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
k59_1590287_1	360094.PXO_00409	4.83e-18	82.8	COG3358@1|root,COG3358@2|Bacteria,1R9CT@1224|Proteobacteria,1SP2S@1236|Gammaproteobacteria,1X42J@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
k59_1590287_2	580332.Slit_0552	3.16e-14	76.3	COG0840@1|root,COG0840@2|Bacteria,1R5W9@1224|Proteobacteria,2VKQP@28216|Betaproteobacteria,44V12@713636|Nitrosomonadales	28216|Betaproteobacteria	NT	SMART chemotaxis sensory transducer	-	-	-	-	-	-	-	-	-	-	-	-	CZB,MCPsignal
k59_1532425_1	1165841.SULAR_03567	1.03e-132	405.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,42NJD@68525|delta/epsilon subdivisions	1224|Proteobacteria	O	Belongs to the peptidase S16 family	ycbZ	-	3.4.21.53	ko:K01338,ko:K04076,ko:K04770	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA_32,Lon_C
k59_1532433_1	709032.Sulku_1158	4.18e-85	256.0	COG2005@1|root,COG3585@1|root,COG2005@2|Bacteria,COG3585@2|Bacteria,1P9SX@1224|Proteobacteria,42RG9@68525|delta/epsilon subdivisions,2YMVF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Transcriptional regulator, ModE family	modE	-	-	ko:K02019	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,TOBE
k59_1532433_2	1537917.JU82_05590	1.15e-88	263.0	2BEW6@1|root,328MU@2|Bacteria,1QAUA@1224|Proteobacteria,42VY6@68525|delta/epsilon subdivisions,2YQED@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1003580_1	661367.LLO_2005	5.76e-21	94.4	COG0642@1|root,COG5001@1|root,COG2205@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1T4ZK@1236|Gammaproteobacteria,1JE05@118969|Legionellales	118969|Legionellales	T	Sensors of blue-light using FAD	-	-	-	-	-	-	-	-	-	-	-	-	BLUF,GGDEF,PAS_9
k59_534589_1	159087.Daro_0773	8.53e-88	275.0	COG1766@1|root,COG1766@2|Bacteria,1MUQR@1224|Proteobacteria,2VI9M@28216|Betaproteobacteria,2KVMR@206389|Rhodocyclales	206389|Rhodocyclales	N	The M ring may be actively involved in energy transduction	fliF	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
k59_1238791_1	887898.HMPREF0551_0835	1.25e-17	81.6	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,2VHFQ@28216|Betaproteobacteria,1K3H7@119060|Burkholderiaceae	28216|Betaproteobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
k59_1238791_2	1304883.KI912532_gene2457	7.48e-86	263.0	COG1448@1|root,COG1448@2|Bacteria,1MUT0@1224|Proteobacteria,2VHNH@28216|Betaproteobacteria,2KUZF@206389|Rhodocyclales	206389|Rhodocyclales	E	Aminotransferase	tyrB	-	2.6.1.57	ko:K00832	ko00270,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	M00024,M00025,M00034,M00040	R00694,R00734,R01731,R07396,R10845	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_1532446_1	1537917.JU82_03955	5.89e-59	187.0	COG1192@1|root,COG1192@2|Bacteria,1N5CA@1224|Proteobacteria,42RDX@68525|delta/epsilon subdivisions,2YQN4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	involved in chromosome partitioning	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
k59_1532446_3	927658.AJUM01000042_gene1558	7.59e-37	130.0	COG0454@1|root,COG0456@2|Bacteria,4NTGT@976|Bacteroidetes,2FUEM@200643|Bacteroidia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k59_885679_1	159087.Daro_1404	4.56e-151	441.0	COG2864@1|root,COG2864@2|Bacteria,1NJEJ@1224|Proteobacteria,2VKG8@28216|Betaproteobacteria,2KY24@206389|Rhodocyclales	206389|Rhodocyclales	P	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1120992_1	159087.Daro_3858	5.8e-99	293.0	COG2974@1|root,COG2974@2|Bacteria,1MXPR@1224|Proteobacteria,2VHD8@28216|Betaproteobacteria,2KVYJ@206389|Rhodocyclales	206389|Rhodocyclales	L	May be involved in recombination	rdgC	-	-	ko:K03554	-	-	-	-	ko00000,ko03400	-	-	-	RdgC
k59_356956_1	944547.ABLL_1585	9.14e-80	248.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,42MMG@68525|delta/epsilon subdivisions,2YMCT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
k59_297920_1	1232453.BAIF02000131_gene1604	2.65e-61	206.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia,26AM7@186813|unclassified Clostridiales	186801|Clostridia	L	COG COG3344 Retron-type reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
k59_767411_2	326298.Suden_0540	6.71e-08	53.1	29VYJ@1|root,30HGQ@2|Bacteria,1Q33E@1224|Proteobacteria,42WQE@68525|delta/epsilon subdivisions,2YQMM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1296381_1	159087.Daro_1518	5.16e-60	191.0	COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria,2VJSK@28216|Betaproteobacteria,2KVXW@206389|Rhodocyclales	206389|Rhodocyclales	S	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
k59_1296381_2	159087.Daro_1519	7.87e-32	115.0	COG4117@1|root,COG4117@2|Bacteria,1MX97@1224|Proteobacteria,2VJ2X@28216|Betaproteobacteria,2KWGW@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome b/b6/petB	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
k59_1826155_1	1537917.JU82_02185	2.88e-95	286.0	COG2374@1|root,COG2374@2|Bacteria,1RCTI@1224|Proteobacteria,42Q2J@68525|delta/epsilon subdivisions,2YNG1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
k59_1296390_1	159087.Daro_3921	5.29e-152	443.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,2VHS3@28216|Betaproteobacteria,2KV81@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
k59_534671_1	580332.Slit_0883	1.78e-125	370.0	COG2710@1|root,COG2710@2|Bacteria,1MWQ4@1224|Proteobacteria,2VIUM@28216|Betaproteobacteria	28216|Betaproteobacteria	C	This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation	nifK	-	1.18.6.1	ko:K02591	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF3364,Oxidored_nitro
k59_122736_1	550540.Fbal_1465	6.18e-55	189.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,1RMFZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	mltD	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008932,GO:0008933,GO:0009893,GO:0016020,GO:0016740,GO:0016757,GO:0019222,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043085,GO:0044093,GO:0044464,GO:0048518,GO:0050789,GO:0050790,GO:0051341,GO:0051353,GO:0061783,GO:0065007,GO:0065009	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
k59_297946_1	1249480.B649_10700	4.35e-210	619.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,43DMZ@68525|delta/epsilon subdivisions,2YMMS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_1826168_1	1249480.B649_03675	4.82e-65	219.0	COG2319@1|root,COG2319@2|Bacteria,1Q4KY@1224|Proteobacteria,42ZEF@68525|delta/epsilon subdivisions,2YR4A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1296415_1	1502770.JQMG01000001_gene1794	2.79e-95	287.0	COG1821@1|root,COG1821@2|Bacteria,1RBY6@1224|Proteobacteria,2VQ4F@28216|Betaproteobacteria,2KMTW@206350|Nitrosomonadales	206350|Nitrosomonadales	S	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3
k59_1238906_1	317025.Tcr_0823	6.76e-89	282.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,1RMUH@1236|Gammaproteobacteria,45ZUB@72273|Thiotrichales	72273|Thiotrichales	C	NADH-quinone oxidoreductase	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
k59_416052_2	583345.Mmol_1949	4.56e-32	120.0	COG1450@1|root,COG1450@2|Bacteria,1NC06@1224|Proteobacteria,2VR15@28216|Betaproteobacteria,2KMPV@206350|Nitrosomonadales	206350|Nitrosomonadales	NU	Bacterial type II and III secretion system protein	-	-	-	-	-	-	-	-	-	-	-	-	Secretin,Secretin_N
k59_534720_1	709032.Sulku_1633	2.41e-100	304.0	COG2206@1|root,COG2206@2|Bacteria,1R53C@1224|Proteobacteria,42R7P@68525|delta/epsilon subdivisions,2YPRS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
k59_767473_1	2340.JV46_04770	6.38e-15	81.3	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMDS@1236|Gammaproteobacteria,1J4XZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs	rne	-	3.1.26.12	ko:K08300	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
k59_1003744_1	452638.Pnec_1128	1.59e-15	75.5	COG3047@1|root,COG3047@2|Bacteria,1NUZJ@1224|Proteobacteria,2VS6T@28216|Betaproteobacteria,1KFIT@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Outer membrane protein beta-barrel domain	ompW	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	ko:K07275	-	-	-	-	ko00000	-	-	-	OmpW
k59_1296437_2	1537917.JU82_05765	2.32e-74	233.0	COG1636@1|root,COG1636@2|Bacteria,1MUG5@1224|Proteobacteria,42M1E@68525|delta/epsilon subdivisions,2YN69@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queH	-	1.17.99.6	ko:K09765	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF208
k59_1179504_2	159087.Daro_1628	1.14e-08	53.9	COG2862@1|root,COG2862@2|Bacteria,1RANN@1224|Proteobacteria,2VK3P@28216|Betaproteobacteria,2KWFA@206389|Rhodocyclales	206389|Rhodocyclales	S	UPF0114 protein	-	-	-	-	-	-	-	-	-	-	-	-	UPF0114
k59_592282_1	387093.SUN_2000	2.24e-30	121.0	COG0457@1|root,COG0457@2|Bacteria,1MXK4@1224|Proteobacteria,42PK9@68525|delta/epsilon subdivisions,2YNXX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
k59_1355037_2	1537917.JU82_09420	2.48e-143	408.0	COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,42MMJ@68525|delta/epsilon subdivisions,2YMJ0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KO	Hydrogenase	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
k59_1648950_1	1537917.JU82_07070	7.22e-107	311.0	COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,42NRX@68525|delta/epsilon subdivisions,2YMSK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
k59_767503_1	62928.azo2954	3.23e-77	246.0	COG0845@1|root,COG5569@1|root,COG0845@2|Bacteria,COG5569@2|Bacteria,1MVAS@1224|Proteobacteria,2VJXV@28216|Betaproteobacteria,2KVT7@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	CusF_Ec,HlyD_D23
k59_6823_1	159087.Daro_3766	4.81e-25	101.0	COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,2VH6N@28216|Betaproteobacteria,2KUN9@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
k59_6823_2	159087.Daro_3765	1.03e-62	194.0	COG0607@1|root,COG0607@2|Bacteria,1REHH@1224|Proteobacteria,2VR3P@28216|Betaproteobacteria,2KWCV@206389|Rhodocyclales	206389|Rhodocyclales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_1532635_1	582744.Msip34_1464	2.54e-27	117.0	COG3170@1|root,COG3170@2|Bacteria,1Q45C@1224|Proteobacteria,2W196@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1826279_1	395494.Galf_2121	8.46e-87	267.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,2VI9I@28216|Betaproteobacteria,44V4J@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Ammonium Transporter Family	-	-	-	ko:K03320,ko:K06580	-	-	-	-	ko00000,ko02000,ko04090	1.A.11,1.A.11.4	-	-	Ammonium_transp
k59_1826287_1	78245.Xaut_2720	1.87e-71	230.0	COG0247@1|root,COG0247@2|Bacteria,1QV1F@1224|Proteobacteria,2TWHJ@28211|Alphaproteobacteria,3F2D6@335928|Xanthobacteraceae	28211|Alphaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Fer4_17,Fer4_8
k59_1707671_1	1165841.SULAR_01310	7.34e-40	142.0	29CAW@1|root,2ZZ9C@2|Bacteria,1Q5FH@1224|Proteobacteria,42Q2S@68525|delta/epsilon subdivisions,2YQ1W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1707671_2	387093.SUN_1320	1.27e-180	508.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,42N3M@68525|delta/epsilon subdivisions,2YMHR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dusB	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
k59_1355112_1	709032.Sulku_2500	6.81e-77	232.0	COG0352@1|root,COG0352@2|Bacteria,1P3Q4@1224|Proteobacteria,42SIF@68525|delta/epsilon subdivisions,2YPJ7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	thiamine-phosphate diphosphorylase activity	-	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	-
k59_1472830_1	1537917.JU82_08245	1.95e-78	245.0	COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,42MBN@68525|delta/epsilon subdivisions,2YMCS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
k59_1707702_1	358220.C380_19005	2.63e-130	386.0	COG0115@1|root,COG0147@1|root,COG0115@2|Bacteria,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2VHXV@28216|Betaproteobacteria,4ABXZ@80864|Comamonadaceae	28216|Betaproteobacteria	EH	TIGRFAM para-aminobenzoate synthase, subunit I	pabB	-	2.6.1.85,4.1.3.38	ko:K01665,ko:K03342	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4,Chorismate_bind
k59_1472851_1	709032.Sulku_2360	1.99e-123	363.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,42NA4@68525|delta/epsilon subdivisions,2YN8R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EGP	transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
k59_592397_1	159087.Daro_0713	2.05e-172	490.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,2VIWB@28216|Betaproteobacteria,2KVB2@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the heme-copper respiratory oxidase family	-	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
k59_1766440_1	159087.Daro_0840	2.87e-100	297.0	COG1639@1|root,COG1639@2|Bacteria,1R4ZN@1224|Proteobacteria,2VQ1P@28216|Betaproteobacteria,2KVUP@206389|Rhodocyclales	206389|Rhodocyclales	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_767603_1	1123393.KB891316_gene1993	1.32e-58	196.0	COG1009@1|root,COG1009@2|Bacteria,1MW9F@1224|Proteobacteria,2VIC8@28216|Betaproteobacteria,1KSTE@119069|Hydrogenophilales	119069|Hydrogenophilales	C	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
k59_767603_2	1123393.KB891316_gene1994	2.69e-42	144.0	2E08B@1|root,32VW1@2|Bacteria,1N4XX@1224|Proteobacteria,2VUWU@28216|Betaproteobacteria,1KS6U@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_592417_1	402881.Plav_0175	2.3e-62	215.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,1JN93@119043|Rhodobiaceae	28211|Alphaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_1590577_1	159087.Daro_1300	9.49e-110	326.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,2VHJJ@28216|Betaproteobacteria,2KV4N@206389|Rhodocyclales	206389|Rhodocyclales	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
k59_845467_1	563040.Saut_0945	2.6e-14	70.1	COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,42SCS@68525|delta/epsilon subdivisions,2YPIF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	Tripartite ATP-independent periplasmic transporter DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
k59_845467_2	1537917.JU82_06225	1.22e-60	188.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,42MXF@68525|delta/epsilon subdivisions,2YMJ8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Mur ligase middle domain	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
k59_77079_1	1249480.B649_11270	8.53e-94	281.0	28M05@1|root,32SJ0@2|Bacteria,1N115@1224|Proteobacteria,42ZGF@68525|delta/epsilon subdivisions,2YRPD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1489770_1	1123518.ARWI01000001_gene2444	8.24e-55	179.0	COG0035@1|root,COG0035@2|Bacteria,1MV4N@1224|Proteobacteria,1RPBG@1236|Gammaproteobacteria,460PB@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
k59_845489_1	159087.Daro_0270	7.89e-89	273.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,2VH55@28216|Betaproteobacteria,2KV07@206389|Rhodocyclales	206389|Rhodocyclales	E	amino acid	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_20736_1	1249480.B649_01935	2.07e-16	76.3	COG0745@1|root,COG0745@2|Bacteria,1QUJR@1224|Proteobacteria,42NQS@68525|delta/epsilon subdivisions,2YN0F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_20736_2	1537917.JU82_11570	1.95e-23	98.2	COG0168@1|root,COG0168@2|Bacteria,1N412@1224|Proteobacteria,42MBI@68525|delta/epsilon subdivisions,2YMWN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Potassium uptake protein	ktrB	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
k59_256687_1	159087.Daro_3544	6.19e-56	176.0	COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,2VU5Y@28216|Betaproteobacteria,2KWKX@206389|Rhodocyclales	206389|Rhodocyclales	M	Recycling of diacylglycerol produced during the turnover of membrane phospholipid	-	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
k59_256687_2	1304883.KI912532_gene1530	1.45e-06	49.7	2C372@1|root,32RBQ@2|Bacteria,1RKIF@1224|Proteobacteria,2VTCM@28216|Betaproteobacteria,2KXNH@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_555241_1	666681.M301_1657	5.06e-77	254.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,2VH5B@28216|Betaproteobacteria,2KKKX@206350|Nitrosomonadales	206350|Nitrosomonadales	OT	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
k59_256690_1	387093.SUN_0687	3.98e-195	576.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42NCZ@68525|delta/epsilon subdivisions,2YNKW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	czcA	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
k59_1606368_1	709032.Sulku_0454	1.22e-64	206.0	COG0618@1|root,COG0618@2|Bacteria,1RADZ@1224|Proteobacteria,43DQA@68525|delta/epsilon subdivisions,2YT8A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	DHH family	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
k59_196852_1	748247.AZKH_1917	1.13e-124	366.0	COG2828@1|root,COG2828@2|Bacteria,1MXVV@1224|Proteobacteria,2VJAW@28216|Betaproteobacteria	28216|Betaproteobacteria	S	AcnD-accessory protein PrpF	-	-	-	-	-	-	-	-	-	-	-	-	PrpF
k59_1195266_1	1485544.JQKP01000010_gene792	7.93e-33	132.0	COG2199@1|root,COG2202@1|root,COG2199@2|Bacteria,COG2202@2|Bacteria,1NWNJ@1224|Proteobacteria,2WHIC@28216|Betaproteobacteria,44WDC@713636|Nitrosomonadales	28216|Betaproteobacteria	T	SMART GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,sCache_3_2
k59_965953_2	640081.Dsui_3221	5.77e-15	75.5	COG2863@1|root,COG2863@2|Bacteria,1N7W9@1224|Proteobacteria,2WEG6@28216|Betaproteobacteria,2KW5A@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome C oxidase, cbb3-type, subunit III	cc43	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
k59_199989_2	709032.Sulku_2489	1.66e-17	81.3	COG3474@1|root,COG3474@2|Bacteria,1R1KB@1224|Proteobacteria,42Z1J@68525|delta/epsilon subdivisions,2YRH9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome c-552 DMSO reductase-like, heme-binding domain	-	-	-	ko:K17052	-	-	-	-	ko00000,ko02000	5.A.3.8	-	-	Cytochrom_C,EB_dh
k59_1785092_1	666681.M301_0064	8.9e-78	236.0	COG3658@1|root,COG3658@2|Bacteria,1PVDW@1224|Proteobacteria,2VUYT@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome b/b6/petB	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
k59_1785092_2	666681.M301_0065	6.82e-25	96.3	COG1858@1|root,COG1858@2|Bacteria,1QVT1@1224|Proteobacteria,2WGTP@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Domain of unknown function (DUF1924)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1924
k59_1197759_1	1249480.B649_09940	3.71e-161	453.0	COG1216@1|root,COG1216@2|Bacteria,1QU2Q@1224|Proteobacteria,43BK5@68525|delta/epsilon subdivisions,2YN4Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
k59_1374796_1	522306.CAP2UW1_2462	3.34e-82	269.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,1KQ5Y@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	V	MMPL family	bepE_2	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_613858_1	709032.Sulku_2508	8.22e-55	172.0	COG1314@1|root,COG1314@2|Bacteria,1NJ1D@1224|Proteobacteria,42TKW@68525|delta/epsilon subdivisions,2YPUI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Preprotein translocase subunit SecG	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
k59_434458_1	709032.Sulku_1461	8.48e-112	330.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,42M5K@68525|delta/epsilon subdivisions,2YMJ2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
k59_259239_1	387093.SUN_0980	1.52e-121	353.0	COG2301@1|root,COG2301@2|Bacteria,1NUDQ@1224|Proteobacteria,42QUW@68525|delta/epsilon subdivisions,2YNZV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the HpcH HpaI aldolase family	citE	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
k59_1726605_1	572477.Alvin_0213	2.95e-71	234.0	COG1216@1|root,COG1216@2|Bacteria,1MX5Z@1224|Proteobacteria,1RMDY@1236|Gammaproteobacteria,1WX7R@135613|Chromatiales	135613|Chromatiales	J	PFAM Glycosyl transferase family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
k59_259243_1	1537917.JU82_03250	2.22e-84	266.0	COG2199@1|root,COG2200@1|root,COG3620@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,COG3620@2|Bacteria,1MVJY@1224|Proteobacteria,42N7E@68525|delta/epsilon subdivisions,2YNE7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PFAM EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF
k59_1312399_1	159087.Daro_1108	2.7e-99	304.0	COG0210@1|root,COG1074@1|root,COG0210@2|Bacteria,COG1074@2|Bacteria,1MWW6@1224|Proteobacteria,2VM7D@28216|Betaproteobacteria,2KXJK@206389|Rhodocyclales	206389|Rhodocyclales	L	UvrD-like helicase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19,NERD,UvrD_C
k59_434491_1	159087.Daro_2674	3.14e-72	218.0	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,2VRWF@28216|Betaproteobacteria,2KWC3@206389|Rhodocyclales	206389|Rhodocyclales	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
k59_434491_2	1304883.KI912532_gene2632	2.71e-41	145.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,2VIM9@28216|Betaproteobacteria,2KUG4@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
k59_1312414_1	1304883.KI912532_gene1954	7.14e-61	192.0	COG4566@1|root,COG4566@2|Bacteria,1N6WR@1224|Proteobacteria,2VK0C@28216|Betaproteobacteria,2KW5Q@206389|Rhodocyclales	206389|Rhodocyclales	K	response regulator	dctR	-	-	ko:K11712	ko02020,map02020	-	-	-	ko00000,ko00001,ko02022	-	-	-	GerE,Response_reg
k59_1312414_2	159087.Daro_2995	6.53e-52	180.0	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VI6T@28216|Betaproteobacteria,2KUUR@206389|Rhodocyclales	206389|Rhodocyclales	T	Signal transduction histidine kinase	dctS	-	2.7.13.3	ko:K11711	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS
k59_1492181_1	748247.AZKH_3454	3.26e-16	75.5	COG0560@1|root,COG0560@2|Bacteria,1RA1A@1224|Proteobacteria,2VMGV@28216|Betaproteobacteria,2KUMW@206389|Rhodocyclales	206389|Rhodocyclales	E	Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
k59_1492181_2	159087.Daro_3182	1.41e-133	389.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,2VHY5@28216|Betaproteobacteria,2KV46@206389|Rhodocyclales	206389|Rhodocyclales	H	Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control	pcnB	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C
k59_1849447_1	1123393.KB891326_gene120	5.83e-78	255.0	COG0348@1|root,COG3901@1|root,COG0348@2|Bacteria,COG3901@2|Bacteria,1MY5M@1224|Proteobacteria,2VH7V@28216|Betaproteobacteria,1KSED@119069|Hydrogenophilales	119069|Hydrogenophilales	CK	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind,Fer4_5
k59_145471_1	1537917.JU82_03945	2.19e-49	166.0	COG0428@1|root,COG0428@2|Bacteria,1MWEZ@1224|Proteobacteria,42NT2@68525|delta/epsilon subdivisions,2YMWF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Mediates zinc uptake. May also transport other divalent cations	zupT	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
k59_1849450_1	159087.Daro_3488	3.16e-154	458.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,2VHDH@28216|Betaproteobacteria,2KVJC@206389|Rhodocyclales	206389|Rhodocyclales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k59_1849450_2	159087.Daro_3489	1.43e-55	181.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2VKR8@28216|Betaproteobacteria,2KW63@206389|Rhodocyclales	206389|Rhodocyclales	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_1143674_1	1238182.C882_3913	3.22e-15	75.5	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,2TR24@28211|Alphaproteobacteria,2JPV8@204441|Rhodospirillales	204441|Rhodospirillales	C	COG1042 Acyl-CoA synthetase (NDP forming)	yfiQ	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
k59_1143674_2	1121861.KB899911_gene1299	1.87e-15	76.3	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2TRII@28211|Alphaproteobacteria,2JQE7@204441|Rhodospirillales	204441|Rhodospirillales	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
k59_904821_1	765912.Thimo_1387	4.61e-12	67.8	COG4251@1|root,COG4251@2|Bacteria	2|Bacteria	T	photoreceptor activity	-	-	2.7.13.3	ko:K07649,ko:K20971	ko02020,ko02025,map02020,map02025	M00457	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	2CSK_N,HATPase_c,HisKA
k59_904821_2	690597.JH730985_gene778	4.96e-09	59.7	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1YM51@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	T	Response regulator sensory box ggdef domain eal	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
k59_374433_1	1537917.JU82_04070	1.12e-91	284.0	COG0778@1|root,COG0778@2|Bacteria,1Q0G9@1224|Proteobacteria,42QDE@68525|delta/epsilon subdivisions,2YMPN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_558766_1	709032.Sulku_0817	3.11e-44	149.0	COG1189@1|root,COG1189@2|Bacteria,1MWP5@1224|Proteobacteria,42R2J@68525|delta/epsilon subdivisions,2YNYE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Hemolysin	tlyA	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
k59_1312454_1	159087.Daro_0706	2.18e-97	302.0	COG1538@1|root,COG4319@1|root,COG1538@2|Bacteria,COG4319@2|Bacteria,1MYX2@1224|Proteobacteria,2VKDN@28216|Betaproteobacteria,2KUPB@206389|Rhodocyclales	206389|Rhodocyclales	MU	COG1538 Outer membrane protein	-	-	-	ko:K12543	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	1.B.17,3.A.1.109.4	-	-	DUF4440,OEP
k59_1143707_1	1249480.B649_00650	2.07e-64	211.0	COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,42MX8@68525|delta/epsilon subdivisions,2YN00@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	flaB	GO:0001539,GO:0005575,GO:0005576,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_IN,Flagellin_N
k59_1438356_1	879212.DespoDRAFT_02106	1.68e-39	150.0	COG1073@1|root,COG1073@2|Bacteria,1RFNW@1224|Proteobacteria,431KH@68525|delta/epsilon subdivisions,2WWRB@28221|Deltaproteobacteria,2MNVE@213118|Desulfobacterales	28221|Deltaproteobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1029391_1	749222.Nitsa_1017	4.53e-78	236.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,42SDX@68525|delta/epsilon subdivisions,2YP47@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
k59_1609037_1	1537917.JU82_11095	3.01e-163	485.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2YN6Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DNA mismatch repair MutS family	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_III,MutS_V
k59_966144_1	439235.Dalk_0751	1.02e-48	175.0	COG3103@1|root,COG3103@2|Bacteria,1MVX1@1224|Proteobacteria,42PXB@68525|delta/epsilon subdivisions,2WJKN@28221|Deltaproteobacteria,2MJ1J@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Sh3 type 3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1302
k59_787940_1	983328.AFGH01000025_gene48	3.36e-55	187.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42M01@68525|delta/epsilon subdivisions,2YMF7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	ABC transporter	msbA	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
k59_1726720_1	709032.Sulku_0150	8.79e-111	326.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,42M4P@68525|delta/epsilon subdivisions,2YME6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	UDP-N-acetylglucosamine 4,6-dehydratase	pseB	-	4.2.1.115	ko:K15894	ko00520,map00520	-	R09697	RC02609	ko00000,ko00001,ko01000	-	-	-	Polysacc_synt_2
k59_904855_2	709032.Sulku_0700	1.1e-87	276.0	COG1256@1|root,COG1749@1|root,COG1256@2|Bacteria,COG1749@2|Bacteria,1MV2M@1224|Proteobacteria,42PBN@68525|delta/epsilon subdivisions,2YMGR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar hook-associated protein	flgK	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k59_259343_1	1236959.BAMT01000001_gene1647	5.09e-47	159.0	COG1235@1|root,COG1235@2|Bacteria,1MVJH@1224|Proteobacteria,2VKJK@28216|Betaproteobacteria,2KMIB@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Beta-lactamase superfamily domain	-	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
k59_1143761_1	572477.Alvin_0749	1.88e-09	59.7	2EUQ5@1|root,33N5X@2|Bacteria,1NM8H@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1374959_1	1123517.JOMR01000001_gene1862	1.53e-174	498.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,1RNJV@1236|Gammaproteobacteria,45ZXN@72273|Thiotrichales	72273|Thiotrichales	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
k59_1374964_1	709032.Sulku_2429	9.09e-23	97.4	COG0834@1|root,COG2199@1|root,COG2202@1|root,COG3829@1|root,COG0834@2|Bacteria,COG2202@2|Bacteria,COG3706@2|Bacteria,COG3829@2|Bacteria,1R7HC@1224|Proteobacteria,42M3W@68525|delta/epsilon subdivisions,2YMI6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	SMART GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_3,PAS_9
k59_787981_1	709032.Sulku_0740	9.12e-71	223.0	COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,42MJ1@68525|delta/epsilon subdivisions,2YMZ8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0212	M20_dimer,Peptidase_M20
k59_787981_2	709032.Sulku_0739	1.28e-59	201.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2YN6Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DNA mismatch repair MutS family	-	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_III,MutS_V
k59_1785250_1	709032.Sulku_0027	3.54e-55	182.0	COG2038@1|root,COG2038@2|Bacteria,1NZFH@1224|Proteobacteria,42NRQ@68525|delta/epsilon subdivisions,2YNQ9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	phosphoribosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DBI_PRT
k59_1785250_2	1537917.JU82_00705	1.45e-22	90.1	COG2087@1|root,COG2087@2|Bacteria,1RH0A@1224|Proteobacteria,42TUT@68525|delta/epsilon subdivisions,2YQ2Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	PFAM Cobinamide kinase cobinamide phosphate guanyltransferase	cobP	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU
k59_558852_1	243230.DR_A0227	6.49e-07	48.5	COG3232@1|root,COG3232@2|Bacteria	2|Bacteria	E	5-carboxymethyl-2-hydroxymuconate isomerase	hpcD	-	4.1.1.68,5.3.3.10	ko:K01826,ko:K05921	ko00350,ko01120,ko01220,map00350,map01120,map01220	M00533	R04134,R04379,R04380,R04482	RC01085,RC01141,RC01162,RC02669	ko00000,ko00001,ko00002,ko01000	-	-	iECIAI1_1343.ECIAI1_4572,iECO103_1326.ECO103_5133,iEKO11_1354.EKO11_3963,iEcHS_1320.EcHS_A4581,iSBO_1134.SBO_4409,iSbBS512_1146.SbBS512_E4887	CHMI
k59_558852_2	279714.FuraDRAFT_2082	2.43e-73	228.0	COG3971@1|root,COG3971@2|Bacteria,1MVVV@1224|Proteobacteria,2VH5E@28216|Betaproteobacteria,2KRB6@206351|Neisseriales	206351|Neisseriales	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
k59_1555994_1	563040.Saut_1471	5.53e-158	460.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MHP@68525|delta/epsilon subdivisions,2YN92@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k59_1197922_1	1537917.JU82_08475	8.3e-66	204.0	COG0680@1|root,COG0680@2|Bacteria,1N3AS@1224|Proteobacteria,43AZK@68525|delta/epsilon subdivisions,2YP7W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Hydrogenase maturation protease	-	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
k59_1197922_2	1537917.JU82_09400	5.94e-37	139.0	COG0068@1|root,COG0068@2|Bacteria,1Q0S6@1224|Proteobacteria,42SF1@68525|delta/epsilon subdivisions,2YPJ0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	HypF finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HYPF
k59_847734_1	1538295.JY96_03090	1.88e-80	255.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,1KKGI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	nitrogen regulation protein NR(I)	ntrC	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_558869_1	159087.Daro_3252	5.08e-32	117.0	COG3161@1|root,COG3161@2|Bacteria,1N8BF@1224|Proteobacteria,2VU5V@28216|Betaproteobacteria,2KXAX@206389|Rhodocyclales	206389|Rhodocyclales	H	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway	ubiC	-	4.1.3.40	ko:K03181	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R01302	RC00491,RC02148	ko00000,ko00001,ko00002,ko01000	-	-	-	Chor_lyase
k59_558869_2	159087.Daro_3253	4.23e-72	219.0	COG1430@1|root,COG1430@2|Bacteria,1MZBJ@1224|Proteobacteria,2VSCK@28216|Betaproteobacteria,2KWQ3@206389|Rhodocyclales	206389|Rhodocyclales	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
k59_22945_1	717231.Flexsi_0218	5.26e-50	171.0	COG0025@1|root,COG0025@2|Bacteria	2|Bacteria	P	sodium:proton antiporter activity	-	-	3.1.3.16	ko:K06382	-	-	-	-	ko00000,ko01000	-	-	-	Na_H_Exchanger
k59_497188_1	317025.Tcr_0411	2.97e-43	148.0	COG2862@1|root,COG2862@2|Bacteria,1RFUX@1224|Proteobacteria,1S75J@1236|Gammaproteobacteria,462RI@72273|Thiotrichales	72273|Thiotrichales	S	Uncharacterized protein family, UPF0114	-	-	-	-	-	-	-	-	-	-	-	-	UPF0114
k59_497188_2	1123399.AQVE01000006_gene3572	6.09e-30	112.0	COG0494@1|root,COG0494@2|Bacteria,1RCX7@1224|Proteobacteria,1S3ZE@1236|Gammaproteobacteria,460TJ@72273|Thiotrichales	72273|Thiotrichales	L	NUDIX domain	-	-	-	ko:K08312	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
k59_79569_1	1249480.B649_11780	7.6e-126	379.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2YN94@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
k59_1082722_1	159087.Daro_2815	4.35e-99	291.0	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,2VHIS@28216|Betaproteobacteria,2KW1K@206389|Rhodocyclales	206389|Rhodocyclales	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07666	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_966284_1	709032.Sulku_1587	4.67e-05	44.7	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,42NCJ@68525|delta/epsilon subdivisions,2YMQJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
k59_966284_2	292415.Tbd_0055	2.39e-08	57.4	COG1472@1|root,COG1472@2|Bacteria,1QUPT@1224|Proteobacteria,2W3S1@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Protein of unknown function (DUF3365)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365
k59_497192_2	1249480.B649_04990	3.53e-67	206.0	COG0735@1|root,COG0735@2|Bacteria,1N0HW@1224|Proteobacteria,43B75@68525|delta/epsilon subdivisions,2YPV3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Belongs to the Fur family	-	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
k59_614176_1	159087.Daro_0265	4.38e-71	236.0	COG0642@1|root,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,2VIXT@28216|Betaproteobacteria,2KUH6@206389|Rhodocyclales	206389|Rhodocyclales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2222,HAMP,HATPase_c,HisKA,Response_reg,dCache_1
k59_1263006_1	1249480.B649_04625	1.03e-47	162.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,42NYD@68525|delta/epsilon subdivisions,2YNI5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Permease, YjgP YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_1082752_1	697282.Mettu_2944	1.22e-09	60.8	COG1538@1|root,COG1538@2|Bacteria,1MUZZ@1224|Proteobacteria,1RQEP@1236|Gammaproteobacteria,1XENY@135618|Methylococcales	135618|Methylococcales	M	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_1082752_2	1158292.JPOE01000002_gene3649	8.81e-19	83.2	COG1846@1|root,COG1846@2|Bacteria,1N7BV@1224|Proteobacteria,2VU53@28216|Betaproteobacteria,1KM8R@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	marR	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
k59_1438538_1	748658.KB907314_gene133	1.77e-28	112.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,1RMSF@1236|Gammaproteobacteria,1WVW6@135613|Chromatiales	135613|Chromatiales	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
k59_1438538_2	1120977.JHUX01000003_gene594	7.28e-12	67.4	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,1RN4V@1236|Gammaproteobacteria,3NIR2@468|Moraxellaceae	1236|Gammaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamB	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0008152,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0016491,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0055114,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
k59_200329_1	1249480.B649_05835	2.46e-88	285.0	COG4191@1|root,COG4252@1|root,COG4191@2|Bacteria,COG4252@2|Bacteria	2|Bacteria	T	Chase2 domain	-	-	2.7.13.3,4.6.1.1	ko:K01768,ko:K13040,ko:K20971	ko00230,ko02020,ko02025,ko04113,ko04213,map00230,map02020,map02025,map04113,map04213	M00514,M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	7TMR-DISM_7TM,CHASE2,HATPase_c,HD,HD_5,Pkinase
k59_904972_1	933801.Ahos_0301	1.59e-41	147.0	COG1013@1|root,arCOG01599@2157|Archaea,2XPQG@28889|Crenarchaeota	28889|Crenarchaeota	C	TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, beta subunit	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
k59_788123_1	159087.Daro_3064	1.64e-133	381.0	COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,2VHPY@28216|Betaproteobacteria,2KUD3@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
k59_812006_1	666681.M301_2508	1.7e-33	130.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,2VH9R@28216|Betaproteobacteria,2KKVW@206350|Nitrosomonadales	206350|Nitrosomonadales	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
k59_393625_1	159087.Daro_3351	3.37e-15	70.5	COG2198@1|root,COG2198@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	ko:K20976	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Hpt,Response_reg
k59_393625_2	861299.J421_2398	5.49e-06	50.1	COG0745@1|root,COG2199@1|root,COG2203@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG3706@2|Bacteria,1ZT7F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	diguanylate cyclase	-	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,Response_reg
k59_1631628_1	709032.Sulku_2516	1.51e-54	180.0	COG2956@1|root,COG2956@2|Bacteria,1QUIS@1224|Proteobacteria,42M7G@68525|delta/epsilon subdivisions,2YMKN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_7,TPR_8
k59_812022_1	748280.NH8B_1377	7.61e-103	318.0	COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,2VH5H@28216|Betaproteobacteria,2KQCR@206351|Neisseriales	206351|Neisseriales	C	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
k59_1166772_1	1165841.SULAR_05213	9.15e-05	43.9	COG0007@1|root,COG0007@2|Bacteria,1MUI0@1224|Proteobacteria,42MCB@68525|delta/epsilon subdivisions,2YNRA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme	-	-	1.3.1.76,2.1.1.107,4.99.1.4	ko:K02302,ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03194,R03947	RC00003,RC00871,RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_7,Sirohm_synth_M,TP_methylase
k59_1166772_2	1165841.SULAR_09304	9.54e-144	426.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,42M9Q@68525|delta/epsilon subdivisions,2YNFG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.20.2.1,1.20.9.1,1.7.7.2	ko:K00367,ko:K00372,ko:K08356	ko00910,ko01120,map00910,map01120	M00531	R00791,R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.6	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_1461666_1	1537917.JU82_03000	4.87e-64	209.0	COG3203@1|root,COG3203@2|Bacteria,1QZ2N@1224|Proteobacteria,42QVI@68525|delta/epsilon subdivisions,2YP28@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1513067_1	709032.Sulku_0599	3.25e-44	148.0	COG1826@1|root,COG1826@2|Bacteria,1NI3F@1224|Proteobacteria,42VD0@68525|delta/epsilon subdivisions,2YQ93@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation	tatB	-	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
k59_1513067_2	827.JFJK01000002_gene961	3.92e-07	52.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,42NGU@68525|delta/epsilon subdivisions,2YMCD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN2	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k59_333282_1	709032.Sulku_1080	6.01e-14	70.9	COG3021@1|root,COG3021@2|Bacteria,1MVPP@1224|Proteobacteria,42TM7@68525|delta/epsilon subdivisions,2YQ62@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
k59_333282_2	709032.Sulku_1079	1.38e-64	210.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,42PV9@68525|delta/epsilon subdivisions,2YMKD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
k59_393637_1	317025.Tcr_1150	2.92e-35	141.0	COG2202@1|root,COG2203@1|root,COG5001@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,45ZZR@72273|Thiotrichales	72273|Thiotrichales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_9
k59_1285606_1	317025.Tcr_1471	4.36e-37	141.0	COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,1RMWX@1236|Gammaproteobacteria,460RM@72273|Thiotrichales	72273|Thiotrichales	N	Flagellar hook protein FlgE	-	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bb_rod,Flg_bbr_C
k59_1805220_1	216596.RL2081	8.99e-14	68.6	COG3326@1|root,COG3326@2|Bacteria,1NGR5@1224|Proteobacteria,2UJDY@28211|Alphaproteobacteria,4BG1C@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF1294
k59_1513077_1	1249480.B649_01770	1.56e-95	282.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,42QYK@68525|delta/epsilon subdivisions,2YNZ8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	ABC transporter, ATP-binding protein	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran
k59_1688820_1	387093.SUN_1485	9.89e-93	295.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,42MMV@68525|delta/epsilon subdivisions,2YMV9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k59_1053702_2	709032.Sulku_1542	1.01e-27	106.0	297UU@1|root,2ZV1D@2|Bacteria,1MXFE@1224|Proteobacteria,430YU@68525|delta/epsilon subdivisions,2YS1X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_98795_1	697282.Mettu_3502	5.13e-17	82.0	COG3290@1|root,COG3447@1|root,COG3614@1|root,COG3920@1|root,COG3290@2|Bacteria,COG3447@2|Bacteria,COG3614@2|Bacteria,COG3920@2|Bacteria,1PGPR@1224|Proteobacteria,1RX1U@1236|Gammaproteobacteria,1XGJY@135618|Methylococcales	135618|Methylococcales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_2
k59_1750094_1	1249480.B649_03935	9.06e-76	231.0	COG2197@1|root,COG2197@2|Bacteria,1N8MU@1224|Proteobacteria,42U0R@68525|delta/epsilon subdivisions,2YT2Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
k59_1106264_1	90814.KL370891_gene639	5.33e-70	235.0	COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,1RPTP@1236|Gammaproteobacteria,45ZRH@72273|Thiotrichales	72273|Thiotrichales	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
k59_397465_1	1249480.B649_09050	9.43e-171	501.0	COG0457@1|root,COG0457@2|Bacteria,1QV15@1224|Proteobacteria,42NKI@68525|delta/epsilon subdivisions,2YMKG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	COG0457 FOG TPR repeat	pflB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_6,TPR_8
k59_1807952_1	1249480.B649_04410	4.75e-35	132.0	COG1187@1|root,COG1187@2|Bacteria,1QZ1N@1224|Proteobacteria,430HW@68525|delta/epsilon subdivisions,2YS1F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	pseudouridine synthase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1288504_1	1304883.KI912532_gene1612	1.49e-16	73.9	COG0251@1|root,COG0251@2|Bacteria,1MZ5K@1224|Proteobacteria,2VU19@28216|Betaproteobacteria,2KWRZ@206389|Rhodocyclales	206389|Rhodocyclales	J	translation initiation inhibitor, yjgF family	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
k59_1288504_2	159087.Daro_3456	2.2e-37	129.0	COG0226@1|root,COG0226@2|Bacteria,1N0PQ@1224|Proteobacteria,2VUBS@28216|Betaproteobacteria,2M03D@206389|Rhodocyclales	206389|Rhodocyclales	P	Part of the ABC transporter complex PstSACB involved in phosphate import	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1874822_1	1000565.METUNv1_02142	9.51e-37	142.0	COG4254@1|root,COG4254@2|Bacteria,1PGBS@1224|Proteobacteria,2VQEE@28216|Betaproteobacteria,2M02Z@206389|Rhodocyclales	206389|Rhodocyclales	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
k59_1170385_1	709032.Sulku_0377	2.27e-64	212.0	COG0778@1|root,COG0778@2|Bacteria,1Q0G9@1224|Proteobacteria,42QDE@68525|delta/epsilon subdivisions,2YMPN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_1634805_1	1165841.SULAR_00290	2.34e-113	343.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2YMXZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	ABC transporter, ATP-binding protein	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
k59_1691636_1	159087.Daro_0653	2.52e-72	218.0	COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,2VR2M@28216|Betaproteobacteria,2KWB8@206389|Rhodocyclales	206389|Rhodocyclales	C	Required for insertion of 4Fe-4S clusters	erpA	-	-	ko:K15724	-	-	-	-	ko00000	-	-	-	Fe-S_biosyn
k59_1691636_2	1121035.AUCH01000025_gene3296	1.87e-20	85.1	COG1664@1|root,COG1664@2|Bacteria,1MZN0@1224|Proteobacteria,2VTZQ@28216|Betaproteobacteria,2KWWR@206389|Rhodocyclales	206389|Rhodocyclales	M	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
k59_1288531_1	709032.Sulku_0621	2.04e-24	93.6	2BSV5@1|root,32MYQ@2|Bacteria,1Q3GB@1224|Proteobacteria,42XA1@68525|delta/epsilon subdivisions,2YQPY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_584842_1	929558.SMGD1_0379	5.94e-06	46.2	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	cheY40H-4	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
k59_584842_2	338966.Ppro_1729	3.57e-13	76.3	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2WJ5U@28221|Deltaproteobacteria,43S5Y@69541|Desulfuromonadales	28221|Deltaproteobacteria	NT	Signal transducing histidine kinase homodimeric	cheA40H	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
k59_1106329_1	709032.Sulku_1952	4.64e-54	184.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42UQ6@68525|delta/epsilon subdivisions,2YQ4D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	PAS fold	-	-	-	ko:K03776	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	PAS_3
k59_1634830_1	1028800.RG540_CH13650	3.88e-40	136.0	2E0FP@1|root,300A6@2|Bacteria,1PQHQ@1224|Proteobacteria,2V2WQ@28211|Alphaproteobacteria,4BJS5@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	Phage endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	Phage_endo_I
k59_1634830_2	1121459.AQXE01000001_gene2769	1.42e-26	107.0	2AFZH@1|root,3163D@2|Bacteria,1RJUP@1224|Proteobacteria,42ZBP@68525|delta/epsilon subdivisions,2WTYW@28221|Deltaproteobacteria,2MDNE@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1398750_1	1249480.B649_07925	5.92e-21	89.7	COG1686@1|root,COG1686@2|Bacteria,1MWZA@1224|Proteobacteria,43AWC@68525|delta/epsilon subdivisions,2YT3V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
k59_1398750_2	709032.Sulku_1377	3.39e-61	194.0	2BUD7@1|root,32PP4@2|Bacteria,1Q4AN@1224|Proteobacteria,42YRC@68525|delta/epsilon subdivisions,2YR91@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1634840_1	709032.Sulku_0036	1.28e-70	229.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42Q5F@68525|delta/epsilon subdivisions,2YPMR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	Cache_3-Cache_2,MCPsignal
k59_1288560_1	1122604.JONR01000007_gene2768	5.61e-55	186.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,1RN88@1236|Gammaproteobacteria,1X3C1@135614|Xanthomonadales	135614|Xanthomonadales	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_1288560_2	1249627.D779_1233	2.93e-35	135.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,1RMQ3@1236|Gammaproteobacteria,1WWB9@135613|Chromatiales	135613|Chromatiales	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
k59_639763_1	159087.Daro_0182	2.13e-12	63.5	COG3109@1|root,COG3109@2|Bacteria,1PS29@1224|Proteobacteria,2VU30@28216|Betaproteobacteria,2KWZI@206389|Rhodocyclales	206389|Rhodocyclales	T	activator of osmoprotectant transporter ProP	proQ	-	-	ko:K03607	-	-	-	-	ko00000	-	-	-	ProQ
k59_639763_2	1304883.KI912532_gene610	2.09e-81	254.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,2VI3N@28216|Betaproteobacteria,2KU6W@206389|Rhodocyclales	206389|Rhodocyclales	J	ribonuclease, Rne Rng family	cafA	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G
k59_1752623_1	709032.Sulku_0150	2.65e-70	220.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,42M4P@68525|delta/epsilon subdivisions,2YME6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	UDP-N-acetylglucosamine 4,6-dehydratase	pseB	-	4.2.1.115	ko:K15894	ko00520,map00520	-	R09697	RC02609	ko00000,ko00001,ko01000	-	-	-	Polysacc_synt_2
k59_1752623_2	1249480.B649_00710	1.56e-19	86.7	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42MTX@68525|delta/epsilon subdivisions,2YMNH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	pseC	-	2.6.1.92	ko:K15895	ko00520,map00520	-	R09825	RC00006,RC00781	ko00000,ko00001,ko01000	-	-	-	DegT_DnrJ_EryC1
k59_169630_1	1249480.B649_03945	1.57e-81	262.0	COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,42MP9@68525|delta/epsilon subdivisions	1224|Proteobacteria	V	ABC transporter, transmembrane region	rtxB	-	-	ko:K12541	ko02010,map02010	M00330	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.109.3,3.A.1.109.4	-	-	ABC_membrane,ABC_tran,Peptidase_C39
k59_169630_2	1249480.B649_03940	5.14e-46	160.0	COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,42MCZ@68525|delta/epsilon subdivisions,2YNNG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	type I secretion membrane fusion protein, HlyD family	-	-	-	ko:K02022,ko:K12542	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	3.A.1.109.4,8.A.1	-	-	Biotin_lipoyl_2,HlyD_3
k59_1464610_1	666681.M301_0437	4.11e-75	243.0	28PH1@1|root,2ZC7N@2|Bacteria,1RAFS@1224|Proteobacteria,2VSSP@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_994743_2	159087.Daro_3329	2.14e-73	226.0	COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,2VIR4@28216|Betaproteobacteria,2KV3M@206389|Rhodocyclales	206389|Rhodocyclales	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.5.1	ko:K01501,ko:K11206	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
k59_584933_1	1101195.Meth11DRAFT_0506	2.08e-39	152.0	COG0715@1|root,COG5001@1|root,COG0715@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KMBP@206350|Nitrosomonadales	206350|Nitrosomonadales	T	PFAM EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,NMT1,PAS_3,PAS_9
k59_1170502_1	1165841.SULAR_07340	4.25e-94	286.0	COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,42M6S@68525|delta/epsilon subdivisions,2YMJG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
k59_1106414_1	1249480.B649_11765	2.68e-130	376.0	COG0144@1|root,COG0144@2|Bacteria,1MWPE@1224|Proteobacteria,42P2T@68525|delta/epsilon subdivisions,2YNNR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N
k59_703044_1	1000565.METUNv1_03062	9.16e-13	65.1	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,2VQ4N@28216|Betaproteobacteria,2KW47@206389|Rhodocyclales	206389|Rhodocyclales	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
k59_703044_2	1279019.ARQK01000056_gene295	7.86e-31	120.0	COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,1RPMB@1236|Gammaproteobacteria,1WWDN@135613|Chromatiales	135613|Chromatiales	S	PFAM Peptidoglycan-binding lysin domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
k59_458391_1	159087.Daro_3786	5.15e-97	287.0	COG0596@1|root,COG0596@2|Bacteria,1MVTG@1224|Proteobacteria,2VJIF@28216|Betaproteobacteria,2KVPG@206389|Rhodocyclales	206389|Rhodocyclales	S	Alpha/beta hydrolase family	-	-	3.7.1.9	ko:K10216	ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R02604,R05362,R05865	RC00272,RC00753,RC00754,RC00755,RC01337,RC01485	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
k59_458391_2	1121004.ATVC01000014_gene2012	1.44e-18	82.4	COG3971@1|root,COG3971@2|Bacteria,1MVVV@1224|Proteobacteria,2VH5E@28216|Betaproteobacteria,2KRB6@206351|Neisseriales	206351|Neisseriales	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
k59_994757_1	266264.Rmet_4978	4.2e-53	172.0	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,2VHIS@28216|Betaproteobacteria,1K642@119060|Burkholderiaceae	28216|Betaproteobacteria	K	regulator	-	-	-	ko:K02483,ko:K07666	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_994757_2	159087.Daro_2297	2.87e-180	519.0	COG0642@1|root,COG2205@2|Bacteria,1N1Z2@1224|Proteobacteria,2VJBG@28216|Betaproteobacteria,2KYEP@206389|Rhodocyclales	206389|Rhodocyclales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_868272_1	159087.Daro_3843	2.63e-125	377.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,2VIA1@28216|Betaproteobacteria,2KVJT@206389|Rhodocyclales	206389|Rhodocyclales	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	spoT	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
k59_458396_1	709032.Sulku_1762	1.23e-24	102.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2YN8I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Abc transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
k59_458396_2	1537917.JU82_03670	1.23e-122	353.0	COG1187@1|root,COG1187@2|Bacteria,1MU6M@1224|Proteobacteria,42RD2@68525|delta/epsilon subdivisions,2YP0D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	rsuA	-	5.4.99.19	ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_283221_2	1122599.AUGR01000017_gene2934	3.08e-27	113.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XHNA@135619|Oceanospirillales	135619|Oceanospirillales	T	Methyl-accepting chemotaxis	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal,PAS_9
k59_283221_3	709032.Sulku_0692	3.66e-06	46.6	COG2010@1|root,COG2010@2|Bacteria,1QZ1X@1224|Proteobacteria,42WCS@68525|delta/epsilon subdivisions,2YQIG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
k59_283235_1	1249480.B649_05345	7.86e-63	212.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,42WJ0@68525|delta/epsilon subdivisions,2YQJR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	PFAM TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_1583647_1	1249480.B649_00180	1.74e-67	219.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,42M81@68525|delta/epsilon subdivisions,2YMTF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_815294_1	1537917.JU82_02025	1.96e-56	188.0	COG0642@1|root,COG2205@2|Bacteria,1Q179@1224|Proteobacteria,4313A@68525|delta/epsilon subdivisions,2YS9S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07645	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	-
k59_815294_2	1537917.JU82_02030	5.71e-108	316.0	COG0745@1|root,COG0745@2|Bacteria,1N7TJ@1224|Proteobacteria,42TRT@68525|delta/epsilon subdivisions,2YPV7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_815294_3	1537917.JU82_02035	2.9e-43	142.0	2DHUN@1|root,30113@2|Bacteria,1Q6JK@1224|Proteobacteria,433A5@68525|delta/epsilon subdivisions,2YSRK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF3240)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3240
k59_744027_1	1444711.CCJF01000004_gene2304	2.42e-15	77.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	aslA	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
k59_1170614_1	62928.azo1327	1.66e-95	292.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,2VHVU@28216|Betaproteobacteria,2KVJF@206389|Rhodocyclales	206389|Rhodocyclales	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	-	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
k59_1398895_1	1249480.B649_10605	5.76e-62	199.0	COG3267@1|root,COG3267@2|Bacteria,1R16B@1224|Proteobacteria,42SY7@68525|delta/epsilon subdivisions,2YPRP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
k59_1464728_1	1304883.KI912532_gene2128	5.83e-112	335.0	COG0427@1|root,COG0427@2|Bacteria,1MUGE@1224|Proteobacteria,2VJUB@28216|Betaproteobacteria,2KVMY@206389|Rhodocyclales	206389|Rhodocyclales	C	acetyl-CoA hydrolase	cat1	-	2.8.3.18	ko:K18118	ko00020,ko00620,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00650,map01100,map01110,map01120,map01130,map01200	M00009,M00011	R10343	RC00012,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
k59_1875047_1	1249480.B649_08650	2.34e-58	200.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2YN6Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DNA mismatch repair MutS family	-	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_III,MutS_V
k59_1338807_1	709032.Sulku_0764	4.16e-114	337.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2YMQG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
k59_932175_2	1249480.B649_10460	8.89e-32	112.0	2B2IW@1|root,31V40@2|Bacteria,1QSZI@1224|Proteobacteria,4332K@68525|delta/epsilon subdivisions,2YSGU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_225375_1	1288494.EBAPG3_20570	1.49e-37	131.0	COG1926@1|root,COG1926@2|Bacteria,1RAG8@1224|Proteobacteria,2VPNZ@28216|Betaproteobacteria,372RS@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Phosphoribosyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
k59_458473_1	1249480.B649_08735	4e-54	187.0	COG1450@1|root,COG1450@2|Bacteria,1MVNC@1224|Proteobacteria,43BJ2@68525|delta/epsilon subdivisions,2YN49@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Type II and III secretion system protein	ctsD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	STN,Secretin,Secretin_N_2
k59_585084_1	754477.Q7C_2285	2.87e-101	302.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,1RNKK@1236|Gammaproteobacteria,46006@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
k59_994872_1	1165841.SULAR_07805	7.67e-109	344.0	COG1629@1|root,COG1629@2|Bacteria,1MX4K@1224|Proteobacteria,42WVW@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
k59_703196_1	709032.Sulku_1907	3.12e-172	488.0	COG0840@1|root,COG0840@2|Bacteria,1PNV4@1224|Proteobacteria,42YFX@68525|delta/epsilon subdivisions,2YRME@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
k59_1583762_1	387093.SUN_0856	4.43e-93	288.0	COG1001@1|root,COG1001@2|Bacteria,1MVFP@1224|Proteobacteria,42NWX@68525|delta/epsilon subdivisions,2YR28@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Adenine deaminase C-terminal domain	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
k59_101537_1	349520.PPE_04023	4.58e-18	88.6	COG0745@1|root,COG0784@1|root,COG4251@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG4251@2|Bacteria,1UIHJ@1239|Firmicutes,4ISI2@91061|Bacilli,2774Z@186822|Paenibacillaceae	91061|Bacilli	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,GAF_2,HATPase_c,HisKA,His_kinase,Response_reg
k59_1583765_1	864051.BurJ1DRAFT_3327	8.76e-58	196.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,2VM9R@28216|Betaproteobacteria,1KKEG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	NADPH-dependent glutamate synthase beta	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Fer4_21,Fer4_7,Pyr_redox_2,Pyr_redox_3
k59_1583765_2	864051.BurJ1DRAFT_3327	9.37e-23	95.9	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,2VM9R@28216|Betaproteobacteria,1KKEG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	NADPH-dependent glutamate synthase beta	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Fer4_21,Fer4_7,Pyr_redox_2,Pyr_redox_3
k59_1583771_1	1141662.OOA_16644	5.87e-36	131.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,1RMCZ@1236|Gammaproteobacteria,3Z82X@586|Providencia	1236|Gammaproteobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	iSbBS512_1146.SbBS512_E0035	DapB_C,DapB_N
k59_893516_1	748247.AZKH_1916	1.9e-42	147.0	COG0583@1|root,COG0583@2|Bacteria,1MUWX@1224|Proteobacteria,2VHTN@28216|Betaproteobacteria,2KZ07@206389|Rhodocyclales	206389|Rhodocyclales	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_1715186_2	159087.Daro_1798	1.42e-51	163.0	2E1GZ@1|root,32WV7@2|Bacteria,1N2FP@1224|Proteobacteria,2VVNJ@28216|Betaproteobacteria,2KXE0@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1715186_3	159087.Daro_1799	3.63e-39	142.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VHES@28216|Betaproteobacteria,2KU7H@206389|Rhodocyclales	206389|Rhodocyclales	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	-	-	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
k59_1597874_1	1304883.KI912532_gene2239	6.68e-103	312.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VHES@28216|Betaproteobacteria,2KU7H@206389|Rhodocyclales	206389|Rhodocyclales	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	-	-	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
k59_1715187_1	322710.Avin_10590	2.88e-89	278.0	COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,1RMZT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	kdpD	GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006970,GO:0007154,GO:0007165,GO:0008134,GO:0008150,GO:0008152,GO:0009593,GO:0009605,GO:0009628,GO:0009651,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031226,GO:0031668,GO:0033554,GO:0035556,GO:0036211,GO:0042221,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051606,GO:0051716,GO:0065007,GO:0071214,GO:0071470,GO:0071472,GO:0071496,GO:0071704,GO:0071944,GO:0104004,GO:0140096,GO:1901564	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,GAF_3,HATPase_c,HisKA,KdpD,Usp
k59_187839_1	317025.Tcr_0878	1.47e-78	244.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,1RMAW@1236|Gammaproteobacteria,45ZMY@72273|Thiotrichales	72273|Thiotrichales	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
k59_1597877_1	1249480.B649_10585	1.11e-74	239.0	COG4972@1|root,COG4972@2|Bacteria,1PZTK@1224|Proteobacteria,42R44@68525|delta/epsilon subdivisions,2YP2H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Pilus assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1835194_1	1249480.B649_11365	7.13e-85	264.0	COG0517@1|root,COG2199@1|root,COG0517@2|Bacteria,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42SZE@68525|delta/epsilon subdivisions,2YR4N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GGDEF
k59_1189264_1	1249480.B649_05910	1.01e-141	416.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,42M1S@68525|delta/epsilon subdivisions,2YMEF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	penicillin-binding protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
k59_1189264_2	1249480.B649_05915	3.99e-72	220.0	2AJ0Z@1|root,319J3@2|Bacteria,1Q2X3@1224|Proteobacteria,42WDT@68525|delta/epsilon subdivisions,2YQI2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1838332_2	1537917.JU82_02935	2.34e-119	342.0	COG3381@1|root,COG3381@2|Bacteria,1R97V@1224|Proteobacteria,4306E@68525|delta/epsilon subdivisions,2YRX0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Nitrate reductase delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_del
k59_1016924_1	1249480.B649_10700	2.79e-179	537.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,43DMZ@68525|delta/epsilon subdivisions,2YMMS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_1365395_1	709032.Sulku_0638	1.37e-27	103.0	COG1331@1|root,COG1331@2|Bacteria,1N55I@1224|Proteobacteria,42VTZ@68525|delta/epsilon subdivisions,2YQJ6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Highly conserved protein containing a thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH
k59_1365395_2	1249480.B649_03155	8.28e-94	276.0	COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,42RJW@68525|delta/epsilon subdivisions,2YP85@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
k59_664437_1	243233.MCA1543	2.91e-77	246.0	COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,1RNUS@1236|Gammaproteobacteria,1XDIP@135618|Methylococcales	135618|Methylococcales	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
k59_1365403_1	582744.Msip34_0153	1.86e-06	49.7	2ARZT@1|root,31HBY@2|Bacteria,1RM6G@1224|Proteobacteria,2VT5G@28216|Betaproteobacteria,2KMUX@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1365403_2	1026882.MAMP_01851	3.84e-67	209.0	COG2109@1|root,COG2109@2|Bacteria,1MUN6@1224|Proteobacteria,1RMH9@1236|Gammaproteobacteria,460G6@72273|Thiotrichales	72273|Thiotrichales	H	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids	-	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Co_AT_N,CobA_CobO_BtuR
k59_1426834_1	1537917.JU82_06155	1.95e-122	360.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2YMN1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DEAD box helicase family	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k59_190368_1	204536.SULAZ_0730	1.75e-86	283.0	COG3696@1|root,COG3696@2|Bacteria	2|Bacteria	P	silver ion transport	czcA	-	-	ko:K07787,ko:K15726	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.2,2.A.6.1.4	-	-	ACR_tran
k59_547324_2	1537917.JU82_03950	5.97e-88	268.0	COG3642@1|root,COG3642@2|Bacteria,1N9S1@1224|Proteobacteria,43B6J@68525|delta/epsilon subdivisions,2YT65@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Mn2 dependent serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1717783_1	159087.Daro_3117	1.32e-18	80.1	297U7@1|root,2ZV0V@2|Bacteria,1RE3I@1224|Proteobacteria,2VRCN@28216|Betaproteobacteria,2KWER@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1717783_2	159087.Daro_3116	1.28e-86	256.0	COG0566@1|root,COG0566@2|Bacteria,1REIN@1224|Proteobacteria,2VU16@28216|Betaproteobacteria,2KYEV@206389|Rhodocyclales	206389|Rhodocyclales	H	SpoU rRNA Methylase family	-	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
k59_487491_1	159087.Daro_0922	7.18e-51	171.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,2VHEH@28216|Betaproteobacteria,2KUWF@206389|Rhodocyclales	206389|Rhodocyclales	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
k59_716372_1	1537917.JU82_10810	2.71e-82	256.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,42NGG@68525|delta/epsilon subdivisions,2YN35@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Nucleotidyltransferase DNA polymerase involved in DNA repair	dinP	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
k59_547353_1	709032.Sulku_0333	1.03e-171	487.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,42MCI@68525|delta/epsilon subdivisions,2YMR4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
k59_896375_1	1537917.JU82_07385	6.19e-54	182.0	COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,42MQ6@68525|delta/epsilon subdivisions,2YNPN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DNA photolyase family	phrB	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
k59_896375_2	1537917.JU82_05680	2.4e-30	115.0	COG0500@1|root,COG2226@2|Bacteria,1NV27@1224|Proteobacteria,42P39@68525|delta/epsilon subdivisions,2YNRW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
k59_487503_1	1121289.JHVL01000003_gene2240	1.18e-102	314.0	COG0606@1|root,COG0606@2|Bacteria,1TPPB@1239|Firmicutes,248T8@186801|Clostridia,36EFG@31979|Clostridiaceae	186801|Clostridia	O	magnesium chelatase	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
k59_250698_1	1442598.JABW01000003_gene94	4.69e-103	308.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,42M4F@68525|delta/epsilon subdivisions,2YMAG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	-	ko:K02474	ko00520,map00520	-	R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_547363_1	1304883.KI912532_gene1795	2.98e-141	427.0	COG0842@1|root,COG1129@1|root,COG0842@2|Bacteria,COG1129@2|Bacteria,1QTT9@1224|Proteobacteria,2WGGY@28216|Betaproteobacteria,2KVF7@206389|Rhodocyclales	206389|Rhodocyclales	V	ABC-type multidrug transport system, ATPase component	-	-	-	ko:K13926	-	-	-	-	ko00000	-	-	-	ABC2_membrane_3,ABC_tran
k59_1838416_1	1121459.AQXE01000001_gene2774	1.28e-69	242.0	COG5108@1|root,COG5108@2|Bacteria,1PIWB@1224|Proteobacteria,42YXG@68525|delta/epsilon subdivisions,2WU1V@28221|Deltaproteobacteria,2M9ED@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase	-	-	-	-	-	-	-	-	-	-	-	-	RNA_pol,RPOL_N
k59_1600392_1	709032.Sulku_2181	2.08e-49	164.0	COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,42MBW@68525|delta/epsilon subdivisions,2YMVQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	ribonuclease BN	rbn	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
k59_1600392_2	1537917.JU82_02540	4.76e-108	323.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,42M0V@68525|delta/epsilon subdivisions,2YMAY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Glycolate oxidase subunit	glcD	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
k59_487538_1	159087.Daro_3843	2.32e-113	345.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,2VIA1@28216|Betaproteobacteria,2KVJT@206389|Rhodocyclales	206389|Rhodocyclales	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	spoT	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
k59_71920_2	1300005.R9RG79_9CAUD	7.87e-25	103.0	4QEFX@10239|Viruses,4QYYG@35237|dsDNA viruses  no RNA stage,4QRRV@28883|Caudovirales,4QNTK@10744|Podoviridae	10744|Podoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1426925_1	1249480.B649_00970	4.42e-150	426.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42MKX@68525|delta/epsilon subdivisions,2YMGF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
k59_1659580_1	1537917.JU82_05270	1.6e-62	194.0	COG0607@1|root,COG0607@2|Bacteria,1R70B@1224|Proteobacteria,42UX5@68525|delta/epsilon subdivisions,2YPT0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Rhodanese-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_777461_1	1249480.B649_11740	2.64e-57	200.0	COG3164@1|root,COG3164@2|Bacteria,1QUYX@1224|Proteobacteria,43CES@68525|delta/epsilon subdivisions,2YTC9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
k59_1838434_1	387093.SUN_1172	3.26e-14	70.5	COG1028@1|root,COG1028@2|Bacteria,1MUCH@1224|Proteobacteria,42NM9@68525|delta/epsilon subdivisions,2YNQC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_1838434_2	563040.Saut_1098	1.44e-35	134.0	COG0069@1|root,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2YNFI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	COGs COG0069 Glutamate synthase domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase
k59_1717828_1	397945.Aave_2838	3.02e-36	141.0	COG3209@1|root,COG4104@1|root,COG3209@2|Bacteria,COG4104@2|Bacteria,1MVV1@1224|Proteobacteria,2VMJI@28216|Betaproteobacteria,4AJCQ@80864|Comamonadaceae	28216|Betaproteobacteria	M	TIGRFAM YD repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	PAAR_motif,RHS,RHS_repeat
k59_1600405_1	1537917.JU82_10890	2.44e-146	420.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,42M9G@68525|delta/epsilon subdivisions,2YMSC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
k59_1544788_1	1304883.KI912532_gene193	6.5e-191	533.0	COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,2VHGS@28216|Betaproteobacteria,2KUZH@206389|Rhodocyclales	206389|Rhodocyclales	C	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
k59_1544788_2	159087.Daro_0714	1.06e-70	217.0	COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,2VIJ2@28216|Betaproteobacteria,2KVRX@206389|Rhodocyclales	206389|Rhodocyclales	C	COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit	-	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
k59_603622_1	709032.Sulku_1383	5.64e-74	227.0	COG0007@1|root,COG0007@2|Bacteria,1MUI0@1224|Proteobacteria,42MCB@68525|delta/epsilon subdivisions,2YNRA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme	-	-	1.3.1.76,2.1.1.107,4.99.1.4	ko:K02302,ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03194,R03947	RC00003,RC00871,RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_7,Sirohm_synth_M,TP_methylase
k59_603622_2	709032.Sulku_1384	2.28e-73	237.0	COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,42PHY@68525|delta/epsilon subdivisions,2YMBI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG0155 Sulfite reductase, beta subunit (hemoprotein)	-	-	1.7.7.1,1.8.7.1	ko:K00366,ko:K00392	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00531	R00790,R00859,R03600	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
k59_1838453_1	1537917.JU82_05665	1.39e-146	415.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,42N7Q@68525|delta/epsilon subdivisions,2YMD4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulatory protein	yebC	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
k59_190463_1	265072.Mfla_0141	2.84e-65	205.0	COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,2VH29@28216|Betaproteobacteria,2KM1F@206350|Nitrosomonadales	206350|Nitrosomonadales	S	PFAM ABC transporter	-	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
k59_190463_2	557598.LHK_02025	3.2e-11	63.2	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,2VIEV@28216|Betaproteobacteria,2KQ95@206351|Neisseriales	206351|Neisseriales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
k59_1017100_1	709032.Sulku_0408	8.36e-30	112.0	COG0726@1|root,COG0726@2|Bacteria,1RCWD@1224|Proteobacteria,42R0P@68525|delta/epsilon subdivisions,2YPBW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
k59_1017100_2	709032.Sulku_0409	1.44e-27	110.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1NQKX@1224|Proteobacteria,43CB3@68525|delta/epsilon subdivisions,2YTAN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG2200 FOG EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,sCache_2
k59_1838488_1	1249480.B649_09045	5.54e-59	194.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,42M7H@68525|delta/epsilon subdivisions,2YMPK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
k59_1133487_1	1165841.SULAR_05818	1.02e-62	204.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,42MAH@68525|delta/epsilon subdivisions,2YMZK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
k59_1133487_2	1165841.SULAR_05813	1.43e-174	498.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,42M2M@68525|delta/epsilon subdivisions,2YMS3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
k59_15977_1	929558.SMGD1_1185	6.2e-170	509.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,42NHZ@68525|delta/epsilon subdivisions,2YMTE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	5-methyltetrahydrofolate--homocysteine methyltransferase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
k59_426106_1	159087.Daro_4113	2.59e-41	143.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,2VJBW@28216|Betaproteobacteria,2KU85@206389|Rhodocyclales	206389|Rhodocyclales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
k59_135256_1	1397284.AYMN01000002_gene2335	1.83e-39	145.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,1RPPQ@1236|Gammaproteobacteria,3ZZQI@613|Serratia	1236|Gammaproteobacteria	C	cytochrome c peroxidase	yhjA	GO:0000302,GO:0003674,GO:0003824,GO:0004130,GO:0004601,GO:0005488,GO:0006091,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009061,GO:0009636,GO:0009987,GO:0010035,GO:0015980,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017144,GO:0019645,GO:0020037,GO:0022900,GO:0022904,GO:0042221,GO:0042493,GO:0042542,GO:0042743,GO:0044237,GO:0045333,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051716,GO:0055114,GO:0070887,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1990748	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C,Haem_bd
k59_307547_1	709032.Sulku_2229	2.5e-153	444.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MSP@68525|delta/epsilon subdivisions,2YNDA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
k59_1017160_1	767817.Desgi_4346	4.47e-59	194.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24G9G@186801|Clostridia,264B5@186807|Peptococcaceae	186801|Clostridia	M	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
k59_1017160_2	1347368.HG964403_gene4297	5.59e-05	46.2	COG0110@1|root,COG0110@2|Bacteria,1V8CV@1239|Firmicutes,4HJ0P@91061|Bacilli,1ZGBH@1386|Bacillus	91061|Bacilli	GM	COG0110 Acetyltransferase (isoleucine patch superfamily)	epsM	GO:0003674,GO:0003824,GO:0008374,GO:0016740,GO:0016746,GO:0016747	-	ko:K19429	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep
k59_366516_1	1537917.JU82_03795	1.11e-136	417.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2YMJS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,NIT,Response_reg
k59_777548_1	1537917.JU82_09590	6.87e-53	176.0	COG1373@1|root,COG1373@2|Bacteria,1QP8R@1224|Proteobacteria,42SQ9@68525|delta/epsilon subdivisions,2YPG4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	ATPase (AAA	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14
k59_1133552_1	709032.Sulku_2067	5.49e-48	172.0	COG0642@1|root,COG3850@1|root,COG2205@2|Bacteria,COG3850@2|Bacteria,1NRP8@1224|Proteobacteria,42Z1P@68525|delta/epsilon subdivisions,2YRFA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	HAMP domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k59_1776710_1	1249480.B649_06720	1.6e-81	249.0	COG0697@1|root,COG0697@2|Bacteria,1PIFB@1224|Proteobacteria,42QAN@68525|delta/epsilon subdivisions,2YNGI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EG	integral membrane protein (DUF6 domain protein)	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_1427069_2	1249480.B649_09430	1.02e-114	333.0	COG0745@1|root,COG0745@2|Bacteria,1PGAE@1224|Proteobacteria,4348Y@68525|delta/epsilon subdivisions,2YREY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_426158_1	1249480.B649_06650	1.05e-95	286.0	COG2199@1|root,COG2199@2|Bacteria,1Q4Z5@1224|Proteobacteria,4306K@68525|delta/epsilon subdivisions,2YRSF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	diguanylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_250853_1	1537917.JU82_09460	2.03e-61	189.0	COG3123@1|root,COG3123@2|Bacteria,1MZ8N@1224|Proteobacteria,42TQH@68525|delta/epsilon subdivisions,2YPWS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions	ppnP	-	2.4.2.1,2.4.2.2	ko:K09913	ko00230,ko00240,map00230,map00240	-	R01561,R01570,R01863,R01876,R02147,R02296,R02297	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	DUF1255
k59_1838603_1	42256.RradSPS_2498	2.04e-31	133.0	COG2197@1|root,COG2202@1|root,COG4585@1|root,COG2197@2|Bacteria,COG2202@2|Bacteria,COG4585@2|Bacteria,2GIXR@201174|Actinobacteria,4CT8E@84995|Rubrobacteria	84995|Rubrobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA_3,PAS_3,PAS_4,PAS_9,Response_reg
k59_777588_1	292415.Tbd_0727	4.46e-81	254.0	COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,2VHAR@28216|Betaproteobacteria,1KRAB@119069|Hydrogenophilales	119069|Hydrogenophilales	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
k59_716496_1	583345.Mmol_1969	3.26e-105	328.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,2VHDH@28216|Betaproteobacteria,2KKHN@206350|Nitrosomonadales	206350|Nitrosomonadales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k59_547579_1	1537917.JU82_05035	4.12e-269	742.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,42MA0@68525|delta/epsilon subdivisions,2YM88@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
k59_190558_1	1472716.KBK24_0123050	4.6e-27	102.0	COG0347@1|root,COG0347@2|Bacteria,1NEYN@1224|Proteobacteria,2W4J7@28216|Betaproteobacteria,1K9WN@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Belongs to the P(II) protein family	-	-	-	-	-	-	-	-	-	-	-	-	P-II
k59_1017251_1	387093.SUN_0080	2.68e-38	135.0	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,42P86@68525|delta/epsilon subdivisions,2YN53@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	iIT341.HP1418	MurB_C
k59_1017251_3	1165841.SULAR_10589	4.01e-45	150.0	COG3034@1|root,COG3034@2|Bacteria,1MXY6@1224|Proteobacteria,430MD@68525|delta/epsilon subdivisions,2YRZH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
k59_839080_1	882.DVU_0552	4.09e-25	105.0	COG1216@1|root,COG1216@2|Bacteria,1QFBR@1224|Proteobacteria,43EHR@68525|delta/epsilon subdivisions,2WVTA@28221|Deltaproteobacteria,2MEK5@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_1659756_1	709032.Sulku_0316	1.92e-98	299.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,42M74@68525|delta/epsilon subdivisions,2YMI1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Peptidase, M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_1133611_2	159087.Daro_1046	4.36e-44	150.0	COG3439@1|root,COG3439@2|Bacteria,1PTXD@1224|Proteobacteria,2W33D@28216|Betaproteobacteria,2KYYQ@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
k59_1544982_1	1132855.KB913035_gene2500	1.93e-150	461.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,2VHF3@28216|Betaproteobacteria,2KM9G@206350|Nitrosomonadales	206350|Nitrosomonadales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_667147_1	1165841.SULAR_01405	2.52e-37	131.0	COG2908@1|root,COG2908@2|Bacteria,1Q1QY@1224|Proteobacteria,42STS@68525|delta/epsilon subdivisions,2YP6A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	protein conserved in bacteria	lpxH	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos
k59_667147_2	1165841.SULAR_01395	1.3e-65	208.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,42MDN@68525|delta/epsilon subdivisions,2YMPS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k59_17729_1	1454004.AW11_00274	4.02e-105	319.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,2VH7C@28216|Betaproteobacteria,1KQAG@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	M	Lipoprotein-releasing system permease protein	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
k59_17729_2	1031711.RSPO_c02254	1.13e-26	105.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,2VHAQ@28216|Betaproteobacteria,1K0K6@119060|Burkholderiaceae	28216|Betaproteobacteria	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
k59_1191388_1	709032.Sulku_0547	1.1e-31	117.0	COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,42NWH@68525|delta/epsilon subdivisions,2YQPR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
k59_1453738_1	1537917.JU82_01135	2.08e-107	310.0	COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,42R6H@68525|delta/epsilon subdivisions,2YP0H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
k59_34110_1	1165841.SULAR_06768	1.22e-140	423.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,42M5Q@68525|delta/epsilon subdivisions,2YM9V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
k59_1622849_1	1249480.B649_09215	1.99e-30	114.0	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,42QRC@68525|delta/epsilon subdivisions,2YNZB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
k59_1622849_2	1249480.B649_09210	5.2e-78	234.0	2DMP9@1|root,32SV1@2|Bacteria,1N17Y@1224|Proteobacteria,42TQF@68525|delta/epsilon subdivisions,2YQ0W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF3015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3015
k59_804363_1	159087.Daro_2720	4.91e-41	147.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,2VHVU@28216|Betaproteobacteria,2KVJF@206389|Rhodocyclales	206389|Rhodocyclales	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	-	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
k59_1681272_1	1537917.JU82_06750	9.43e-91	292.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,42M5Q@68525|delta/epsilon subdivisions,2YM9V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
k59_804383_1	159087.Daro_3163	6.97e-68	210.0	COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,2VJCP@28216|Betaproteobacteria,2KW05@206389|Rhodocyclales	206389|Rhodocyclales	S	SNARE associated Golgi protein	dedA	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
k59_1326386_1	1354303.M917_2703	6.6e-14	74.7	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RMU1@1236|Gammaproteobacteria,3NJVR@468|Moraxellaceae	1236|Gammaproteobacteria	L	Helicase associated domain (HA2)  Add an annotation	hrpA	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
k59_1326386_2	1168067.JAGP01000001_gene851	7.34e-30	112.0	COG0491@1|root,COG0491@2|Bacteria,1MURA@1224|Proteobacteria,1RN27@1236|Gammaproteobacteria,460KK@72273|Thiotrichales	72273|Thiotrichales	P	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_1571592_2	1365176.N186_02270	1.27e-19	87.8	COG1355@1|root,arCOG01728@2157|Archaea,2XPQS@28889|Crenarchaeota	28889|Crenarchaeota	S	Belongs to the MEMO1 family	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
k59_448150_1	709032.Sulku_0961	1.78e-43	150.0	COG0019@1|root,COG0019@2|Bacteria,1MW3T@1224|Proteobacteria,42MVP@68525|delta/epsilon subdivisions,2YMY4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the Orn Lys Arg decarboxylase class-II family. NspC subfamily	nspC	-	4.1.1.96	ko:K13747	ko00330,ko01100,map00330,map01100	-	R09081,R09082	RC00299	ko00000,ko00001,ko01000	-	-	-	Orn_DAP_Arg_deC
k59_448150_2	1537917.JU82_01200	8.14e-47	166.0	COG3206@1|root,COG3206@2|Bacteria,1Q26P@1224|Proteobacteria,42V2K@68525|delta/epsilon subdivisions,2YQ9I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1045996_1	709032.Sulku_0336	4.01e-32	122.0	COG1463@1|root,COG1463@2|Bacteria,1RFFS@1224|Proteobacteria,42P4P@68525|delta/epsilon subdivisions,2YNNZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
k59_1045996_2	1249480.B649_01515	5.85e-32	124.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,42N34@68525|delta/epsilon subdivisions,2YMFS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_C
k59_1622917_2	159087.Daro_1059	8.98e-51	166.0	28HPC@1|root,2Z7XD@2|Bacteria,1PQBE@1224|Proteobacteria,2W9MZ@28216|Betaproteobacteria,2KZNJ@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of unknown function (DUF4337)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4337
k59_215327_1	1304883.KI912532_gene150	3.73e-74	233.0	COG1705@1|root,COG3951@1|root,COG1705@2|Bacteria,COG3951@2|Bacteria,1MX2W@1224|Proteobacteria,2VH35@28216|Betaproteobacteria,2KW3R@206389|Rhodocyclales	206389|Rhodocyclales	N	Flagellar rod assembly protein muramidase FlgJ	flgJ	-	-	ko:K02395	-	-	-	-	ko00000,ko02035	-	-	-	Glucosaminidase,Rod-binding
k59_1326439_2	1249480.B649_02710	8e-76	233.0	COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,42NWH@68525|delta/epsilon subdivisions,2YQPR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
k59_573542_1	709032.Sulku_0582	1.73e-63	199.0	29VYJ@1|root,30HGQ@2|Bacteria,1Q33E@1224|Proteobacteria,42WQE@68525|delta/epsilon subdivisions,2YQMM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_34208_2	1304883.KI912532_gene2557	2.83e-36	132.0	COG0304@1|root,COG0304@2|Bacteria,1R6NI@1224|Proteobacteria,2VN43@28216|Betaproteobacteria,2KX3P@206389|Rhodocyclales	206389|Rhodocyclales	IQ	Beta-ketoacyl synthase, C-terminal domain	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_918517_2	1158338.JNLJ01000001_gene376	2.58e-10	61.2	arCOG03638@1|root,2Z8W3@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1538)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1538
k59_1797593_1	598659.NAMH_1492	5.16e-11	65.1	COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,42M9R@68525|delta/epsilon subdivisions,2YM9K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	transporter solute receptor, DctP family	-	-	-	ko:K11688	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctP
k59_1797593_2	748247.AZKH_1919	3.29e-109	319.0	COG3090@1|root,COG3090@2|Bacteria,1R3YK@1224|Proteobacteria,2VQMP@28216|Betaproteobacteria,2KVXN@206389|Rhodocyclales	206389|Rhodocyclales	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	ko:K11689	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctQ
k59_1681338_1	1120999.JONM01000005_gene3827	2.85e-93	295.0	COG0643@1|root,COG3850@1|root,COG0643@2|Bacteria,COG3850@2|Bacteria,1MUAG@1224|Proteobacteria,2VJSZ@28216|Betaproteobacteria,2KQ8J@206351|Neisseriales	206351|Neisseriales	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,Hpt
k59_982523_1	90813.JQMT01000001_gene175	1.26e-53	177.0	COG0191@1|root,COG0191@2|Bacteria,1MURX@1224|Proteobacteria,1RQUC@1236|Gammaproteobacteria,45ZXX@72273|Thiotrichales	72273|Thiotrichales	G	Fructose-bisphosphate aldolase, class II, Calvin cycle subtype	-	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
k59_982523_2	903503.MEPCIT_131	5.73e-14	73.6	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Belongs to the pyruvate kinase family	pykA	GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	e_coli_core.b1854,iAF1260.b1854,iB21_1397.B21_01813,iBWG_1329.BWG_1668,iEC042_1314.EC042_2021,iECBD_1354.ECBD_1784,iECB_1328.ECB_01825,iECDH10B_1368.ECDH10B_1995,iECDH1ME8569_1439.ECDH1ME8569_1801,iECD_1391.ECD_01825,iECO103_1326.ECO103_2044,iECO111_1330.ECO111_2362,iECO26_1355.ECO26_2692,iECUMN_1333.ECUMN_2152,iETEC_1333.ETEC_1887,iEcDH1_1363.EcDH1_1786,iEcE24377_1341.EcE24377A_2084,iEcHS_1320.EcHS_A1947,iEcSMS35_1347.EcSMS35_1332,iEcolC_1368.EcolC_1778,iG2583_1286.G2583_2306,iJO1366.b1854,iJR904.b1854,iSBO_1134.SBO_1162,iSSON_1240.SSON_1294,iSbBS512_1146.SbBS512_E2130,iUMNK88_1353.UMNK88_2326,iY75_1357.Y75_RS09740	PK,PK_C
k59_34227_2	387093.SUN_2133	2.27e-108	335.0	COG0305@1|root,COG1372@1|root,COG0305@2|Bacteria,COG1372@2|Bacteria,1MUG9@1224|Proteobacteria,42M7X@68525|delta/epsilon subdivisions,2YM91@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	GO:0003674,GO:0005488,GO:0005515,GO:0042802	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
k59_1797609_2	1249480.B649_07220	2.31e-100	296.0	COG1994@1|root,COG1994@2|Bacteria,1N531@1224|Proteobacteria,43AZN@68525|delta/epsilon subdivisions,2YP0U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
k59_1681373_1	1249480.B649_04670	6.22e-95	295.0	COG2197@1|root,COG4191@1|root,COG2197@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42R06@68525|delta/epsilon subdivisions,2YP00@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9
k59_1622990_1	552811.Dehly_0322	1.2e-33	126.0	COG0732@1|root,COG0732@2|Bacteria,2GB0V@200795|Chloroflexi,34DQ7@301297|Dehalococcoidia	2|Bacteria	L	PFAM restriction modification system DNA specificity domain	hsdS	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
k59_918581_1	1537917.JU82_10790	3.8e-70	225.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,42MTY@68525|delta/epsilon subdivisions,2YMHI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
k59_918581_2	498761.HM1_3059	1.32e-05	45.8	COG1826@1|root,COG1826@2|Bacteria	2|Bacteria	U	protein secretion	tatA	GO:0002790,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009977,GO:0009987,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032940,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03116,ko:K03425	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
k59_691956_1	709032.Sulku_1949	8.3e-108	319.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,42M27@68525|delta/epsilon subdivisions,2YNWH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
k59_1096111_1	1165841.SULAR_05848	2.87e-56	184.0	COG2515@1|root,COG2515@2|Bacteria,1R87T@1224|Proteobacteria,42MPC@68525|delta/epsilon subdivisions,2YN3K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	1-aminocyclopropane-1-carboxylate deaminase	acd	-	3.5.99.7	ko:K01505	ko00270,map00270	-	R00997	RC00419	ko00000,ko00001,ko01000	-	-	-	-
k59_1096111_2	1165841.SULAR_05843	1.79e-32	123.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,42M3R@68525|delta/epsilon subdivisions,2YN91@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
k59_1505035_1	1304883.KI912532_gene498	2.24e-148	447.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2VHCZ@28216|Betaproteobacteria,2KVY9@206389|Rhodocyclales	206389|Rhodocyclales	P	AcrB/AcrD/AcrF family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
k59_1278924_1	1537917.JU82_11475	3.97e-71	230.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,42MW6@68525|delta/epsilon subdivisions,2YNJR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	potassium channel protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans,Ion_trans_2,TrkA_C,TrkA_N
k59_1211973_1	709032.Sulku_1299	6.46e-98	285.0	2DBX8@1|root,2ZBN7@2|Bacteria,1RABM@1224|Proteobacteria,42TEY@68525|delta/epsilon subdivisions,2YPN1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Nitrogen fixation protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF269
k59_1864851_1	713586.KB900536_gene1315	5.57e-92	285.0	COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,1RNFN@1236|Gammaproteobacteria,1WZY2@135613|Chromatiales	135613|Chromatiales	C	Aldehyde dehydrogenase family	-	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_1571787_1	709032.Sulku_2186	1.82e-109	335.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,42MNH@68525|delta/epsilon subdivisions,2YMIP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C
k59_1797726_1	1249480.B649_09275	5.86e-93	278.0	COG1234@1|root,COG1234@2|Bacteria	2|Bacteria	L	tRNA 3'-trailer cleavage	-	-	3.1.26.11,3.1.4.17	ko:K00784,ko:K01120	ko00230,ko03013,map00230,map03013	-	R00191,R01234	RC00296	ko00000,ko00001,ko01000,ko03016	-	-	-	GAF,HD_5,Lactamase_B_2,PDEase_II
k59_804617_1	1249480.B649_01535	4.83e-91	292.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YMHP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF,PAS_9
k59_1681488_1	1304883.KI912532_gene90	6.32e-92	297.0	COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,2VHX1@28216|Betaproteobacteria,2KUPN@206389|Rhodocyclales	206389|Rhodocyclales	NU	COG3170 Tfp pilus assembly protein FimV	-	-	-	ko:K08086	-	-	-	-	ko00000	-	-	-	LysM
k59_1741336_1	511062.GU3_01980	1.41e-17	87.8	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,1RMH1@1236|Gammaproteobacteria,1Y3NC@135624|Aeromonadales	135624|Aeromonadales	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
k59_918755_1	1537917.JU82_08205	1.77e-91	287.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,42N1K@68525|delta/epsilon subdivisions,2YMYX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1g,tRNA_bind
k59_1159330_1	1537917.JU82_05760	1.4e-93	273.0	COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,42SCN@68525|delta/epsilon subdivisions,2YP5R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0019171	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
k59_1159330_2	1537917.JU82_05755	1.45e-12	65.5	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,42NPG@68525|delta/epsilon subdivisions,2YMG4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iIT341.HP1375	Acetyltransf_11,Hexapep
k59_1505135_1	709032.Sulku_2265	1.25e-19	90.9	COG2199@1|root,COG3221@1|root,COG3437@1|root,COG2199@2|Bacteria,COG3221@2|Bacteria,COG3437@2|Bacteria,1RGCV@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD
k59_1797798_1	1165841.SULAR_06958	5.66e-103	307.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,42NCH@68525|delta/epsilon subdivisions,2YMW7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_1389363_1	709032.Sulku_2222	8.74e-146	427.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,43BJ8@68525|delta/epsilon subdivisions,2YMMJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	penicillin-binding protein	pbpA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
k59_325050_1	663321.REG_0255	3.58e-38	144.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,1RMMQ@1236|Gammaproteobacteria,282XJ@191675|unclassified Enterobacteriaceae	1236|Gammaproteobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
k59_1161845_2	709032.Sulku_1775	2.25e-07	51.6	COG1092@1|root,COG1092@2|Bacteria,1PUHQ@1224|Proteobacteria,42Q87@68525|delta/epsilon subdivisions,2YNGM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the methyltransferase superfamily	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
k59_1457297_1	1537917.JU82_00190	3.76e-105	310.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,42P1N@68525|delta/epsilon subdivisions,2YTRU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
k59_1457301_1	305700.B447_19099	3.2e-39	148.0	COG5001@1|root,COG5001@2|Bacteria,1QV5H@1224|Proteobacteria,2WGPI@28216|Betaproteobacteria,2KUI8@206389|Rhodocyclales	206389|Rhodocyclales	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,LapD_MoxY_N
k59_695249_1	709032.Sulku_0357	1.09e-79	251.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42S65@68525|delta/epsilon subdivisions,2YP56@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
k59_37663_1	1132855.KB913035_gene22	1.34e-75	234.0	COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,2VHEU@28216|Betaproteobacteria,2KKRC@206350|Nitrosomonadales	206350|Nitrosomonadales	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
k59_1457306_1	709032.Sulku_0145	5.62e-84	256.0	COG0775@1|root,COG0775@2|Bacteria,1QSEF@1224|Proteobacteria,42X56@68525|delta/epsilon subdivisions,2YQPV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	-	-	-	-	-	-	-	-	-	-	-	-	PNP_UDP_1
k59_1745231_1	859657.RPSI07_2516	2.76e-56	189.0	COG3562@1|root,COG3562@2|Bacteria,1MUZT@1224|Proteobacteria,2VN14@28216|Betaproteobacteria,1K2IM@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Capsule polysaccharide biosynthesis protein	-	-	-	ko:K07265	-	-	-	-	ko00000	-	-	-	Capsule_synth
k59_1281696_1	1235457.C404_28045	3.4e-90	270.0	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,2VHN6@28216|Betaproteobacteria,1K47T@119060|Burkholderiaceae	28216|Betaproteobacteria	L	ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
k59_274210_1	159087.Daro_2848	6.38e-235	654.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,2VH1A@28216|Betaproteobacteria,2KVEX@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k59_1575371_2	1249480.B649_03315	5.14e-15	74.3	COG1060@1|root,COG1060@2|Bacteria,1QN23@1224|Proteobacteria,42M6Z@68525|delta/epsilon subdivisions,2YMA7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate	mqnE	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
k59_218669_1	709032.Sulku_1130	3.71e-83	248.0	COG0352@1|root,COG0352@2|Bacteria,1Q57E@1224|Proteobacteria,42T8S@68525|delta/epsilon subdivisions,2YPQM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Thiamine monophosphate synthase	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
k59_1281738_1	709032.Sulku_1477	5.24e-95	288.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,42MV0@68525|delta/epsilon subdivisions,2YMKF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	ABC-type transport system involved in lipoprotein release permease component	lolC	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_1330713_1	690850.Desaf_1310	4.9e-24	112.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,42NK9@68525|delta/epsilon subdivisions,2WMCQ@28221|Deltaproteobacteria,2MH9G@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
k59_1575415_1	1163617.SCD_n00706	1.65e-70	233.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,2VM4W@28216|Betaproteobacteria	28216|Betaproteobacteria	G	alpha-glucan phosphorylase	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
k59_451206_1	1537917.JU82_08665	5.07e-113	336.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,42M7A@68525|delta/epsilon subdivisions,2YNCK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k59_632490_1	1255043.TVNIR_2416	1.02e-112	362.0	COG0784@1|root,COG2198@1|root,COG2202@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2202@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,1SVEC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_9,Response_reg
k59_632493_1	1121456.ATVA01000015_gene2492	4.13e-29	122.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WJCX@28221|Deltaproteobacteria,2MH92@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,CHASE,DUF3365,GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,PilJ,Response_reg,dCache_1
k59_1575458_1	1249480.B649_09100	2.87e-129	375.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,42N6U@68525|delta/epsilon subdivisions,2YMCX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	lipid a biosynthesis	waaM	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
k59_451246_1	709032.Sulku_1412	1.97e-18	77.4	2AK4P@1|root,31AUI@2|Bacteria,1Q664@1224|Proteobacteria,42X10@68525|delta/epsilon subdivisions,2YQR8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1800763_1	387093.SUN_1579	3.91e-91	284.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,42MW6@68525|delta/epsilon subdivisions,2YNJR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	potassium channel protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans,Ion_trans_2,TrkA_C,TrkA_N
k59_1330773_2	1537917.JU82_02115	2.64e-32	113.0	COG4736@1|root,COG4736@2|Bacteria,1QDIU@1224|Proteobacteria,42V2T@68525|delta/epsilon subdivisions,2YQ9S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	cytochrome c oxidase	ccoQ	-	-	ko:K00407	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixQ
k59_576860_1	159087.Daro_0174	5.37e-118	370.0	COG0110@1|root,COG0663@1|root,COG1020@1|root,COG0110@2|Bacteria,COG0663@2|Bacteria,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,2VHRU@28216|Betaproteobacteria,2KW0H@206389|Rhodocyclales	206389|Rhodocyclales	Q	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Hexapep,PP-binding
k59_695386_1	765911.Thivi_1735	5.84e-31	120.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,1RMYV@1236|Gammaproteobacteria,1WWCI@135613|Chromatiales	135613|Chromatiales	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
k59_695386_2	279714.FuraDRAFT_2838	7.01e-45	148.0	COG3536@1|root,COG3536@2|Bacteria,1MZ5M@1224|Proteobacteria,2VR9K@28216|Betaproteobacteria,2KREN@206351|Neisseriales	206351|Neisseriales	S	Protein of unknown function (DUF971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF971
k59_826706_1	1249480.B649_02825	1.47e-136	417.0	COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2YMB9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	chemotaxis protein	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k59_1295741_1	1249480.B649_03420	1.35e-116	344.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,42MJT@68525|delta/epsilon subdivisions,2YMEB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
k59_1765536_1	159087.Daro_3776	2.32e-119	351.0	2C4IG@1|root,2Z8A1@2|Bacteria,1QTHZ@1224|Proteobacteria,2VN98@28216|Betaproteobacteria,2KVXJ@206389|Rhodocyclales	206389|Rhodocyclales	S	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1329
k59_1237968_1	1537917.JU82_04300	9.32e-88	274.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42MV6@68525|delta/epsilon subdivisions,2YMMC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CHASE3,MCPsignal,NIT
k59_415327_1	1304883.KI912532_gene2379	7.05e-153	433.0	COG1518@1|root,COG1518@2|Bacteria,1MX9W@1224|Proteobacteria,2VNWK@28216|Betaproteobacteria	28216|Betaproteobacteria	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas1	-	-	ko:K15342	-	-	-	-	ko00000,ko02048,ko03400	-	-	-	Cas_Cas1
k59_826746_1	367737.Abu_0831	3.55e-16	77.4	COG3279@1|root,COG3279@2|Bacteria,1MVJI@1224|Proteobacteria,42T4C@68525|delta/epsilon subdivisions,2YPPT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
k59_826746_2	1165841.SULAR_01963	9.51e-33	124.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,42R4U@68525|delta/epsilon subdivisions,2YNY0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
k59_179783_1	159087.Daro_0923	2.53e-25	104.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,2VH14@28216|Betaproteobacteria,2KVAY@206389|Rhodocyclales	206389|Rhodocyclales	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
k59_179783_2	1120999.JONM01000021_gene130	4.19e-38	138.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,2VHEH@28216|Betaproteobacteria,2KPHJ@206351|Neisseriales	206351|Neisseriales	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
k59_826763_1	1537917.JU82_11405	4.06e-14	68.2	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,42RNC@68525|delta/epsilon subdivisions,2YPBE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL,UPF0547
k59_826763_2	709032.Sulku_0839	4.99e-132	385.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,42MAR@68525|delta/epsilon subdivisions,2YMC4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	ABC transporter	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_297383_1	326298.Suden_0916	4.09e-33	134.0	COG0755@1|root,COG1333@1|root,COG0755@2|Bacteria,COG1333@2|Bacteria,1RG0A@1224|Proteobacteria,42N37@68525|delta/epsilon subdivisions,2YMXW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Cytochrome c biogenesis protein	ccsBA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
k59_1531780_1	398527.Bphyt_4150	1.06e-10	65.9	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2VI5V@28216|Betaproteobacteria,1K1DV@119060|Burkholderiaceae	28216|Betaproteobacteria	MU	TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
k59_1531780_2	1449345.JHWC01000008_gene1750	6.68e-42	155.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YM7R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Efflux pump membrane transporter	cmeB	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_415372_1	1537917.JU82_08350	8.02e-70	230.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,42KZ9@68525|delta/epsilon subdivisions,2YMS4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_1354346_1	709032.Sulku_2369	3.7e-19	84.0	COG0760@1|root,COG0760@2|Bacteria,1N20M@1224|Proteobacteria,42SXW@68525|delta/epsilon subdivisions,2YPHS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase_2,SurA_N,SurA_N_3
k59_1354346_2	1537917.JU82_02450	8.66e-310	845.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,42M14@68525|delta/epsilon subdivisions,2YMWB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
k59_1354346_3	1249480.B649_11225	1.2e-70	216.0	COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,42SQQ@68525|delta/epsilon subdivisions,2YPM8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
k59_1354346_4	1249480.B649_11230	1.82e-135	383.0	COG0717@1|root,COG0717@2|Bacteria,1MV2J@1224|Proteobacteria,42MV8@68525|delta/epsilon subdivisions,2YMAE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the dCTP deaminase family	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
k59_651394_1	1304883.KI912532_gene2310	1.32e-84	258.0	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2VK14@28216|Betaproteobacteria,2KVP1@206389|Rhodocyclales	206389|Rhodocyclales	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
k59_415378_1	314282.PCNPT3_12360	1.25e-82	261.0	COG0208@1|root,COG0208@2|Bacteria,1MWUS@1224|Proteobacteria,1RZEX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Ribonucleotide reductase beta	-	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
k59_415378_2	1236976.JCM16418_5017	4.06e-72	241.0	COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,4H9X0@91061|Bacilli	91061|Bacilli	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_red_lgC
k59_533938_1	1249480.B649_09870	3e-23	105.0	COG1629@1|root,COG4771@2|Bacteria,1RKNG@1224|Proteobacteria,43DI3@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	Outer membrane protein beta-barrel family	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_6055_2	709032.Sulku_2499	5.77e-152	429.0	COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,42MWD@68525|delta/epsilon subdivisions,2YMEM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the BI1 family	-	-	-	ko:K19416	-	M00742	-	-	ko00000,ko00002,ko02000	1.A.14.2.1	-	-	Bax1-I
k59_1002880_1	709032.Sulku_2162	2.07e-137	395.0	COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,42NRV@68525|delta/epsilon subdivisions,2YMK2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
k59_1002880_2	1249480.B649_10210	1.29e-137	395.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,42MU6@68525|delta/epsilon subdivisions,2YMMA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iIT341.HP0202	ACP_syn_III,ACP_syn_III_C
k59_885107_1	1172190.M947_01020	2.47e-39	138.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,42NEA@68525|delta/epsilon subdivisions,2YN5P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
k59_885107_3	1280689.AUJC01000008_gene2932	3.69e-32	117.0	COG3339@1|root,COG3339@2|Bacteria,1VAM6@1239|Firmicutes,24KQN@186801|Clostridia,36KET@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
k59_1178832_1	1165841.SULAR_00105	1.83e-76	231.0	COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,42N6H@68525|delta/epsilon subdivisions,2YM7S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
k59_1825475_1	159087.Daro_4134	1.02e-77	239.0	COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,2VIBZ@28216|Betaproteobacteria,2KUXF@206389|Rhodocyclales	206389|Rhodocyclales	GM	epimerase dehydratase	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	Epimerase,NAD_binding_10
k59_1825475_2	1304883.KI912532_gene895	3.9e-87	267.0	COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,2VIN5@28216|Betaproteobacteria,2KUCQ@206389|Rhodocyclales	206389|Rhodocyclales	J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases	cca	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
k59_239331_1	1304883.KI912532_gene2355	4.92e-88	276.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,2VHEB@28216|Betaproteobacteria,2KWDX@206389|Rhodocyclales	206389|Rhodocyclales	E	COG0010 Arginase agmatinase formimionoglutamate hydrolase, arginase family	rocD	-	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3,Arginase
k59_297442_1	929558.SMGD1_1050	1.03e-67	213.0	COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,42MX8@68525|delta/epsilon subdivisions,2YRW9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	-	-	-	-	-	-	-	-	-	-	-	-	Flagellin_C,Flagellin_N
k59_1648262_1	1537917.JU82_10775	4.39e-23	100.0	COG0745@1|root,COG0745@2|Bacteria,1QXJT@1224|Proteobacteria,42V47@68525|delta/epsilon subdivisions,2YQ8S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	RESPONSE REGULATOR receiver	-	-	-	ko:K07288	-	-	-	-	ko00000	-	-	-	-
k59_415424_1	159087.Daro_3492	1.82e-64	204.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,2VHI8@28216|Betaproteobacteria,2KU6A@206389|Rhodocyclales	206389|Rhodocyclales	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxC
k59_415424_2	1304883.KI912532_gene1577	1.86e-34	127.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,2VH0S@28216|Betaproteobacteria,2KV6H@206389|Rhodocyclales	206389|Rhodocyclales	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
k59_474590_1	686340.Metal_2229	1.38e-31	130.0	COG2202@1|root,COG4191@1|root,COG5000@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,COG5000@2|Bacteria,1RCM9@1224|Proteobacteria,1T538@1236|Gammaproteobacteria,1XG6C@135618|Methylococcales	135618|Methylococcales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_3,PAS_4
k59_1648266_1	1249480.B649_05840	4.17e-26	101.0	COG2885@1|root,COG2885@2|Bacteria,1MZKA@1224|Proteobacteria,42U2D@68525|delta/epsilon subdivisions,2YQ5B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
k59_1648266_2	420324.KI911965_gene426	2.78e-19	93.2	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2TRTY@28211|Alphaproteobacteria,1JTBQ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	T	PFAM adenylyl cyclase class-3 4 guanylyl cyclase	cyaD	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
k59_62956_1	1537917.JU82_08035	2.66e-44	153.0	COG2354@1|root,COG2354@2|Bacteria,1MVYU@1224|Proteobacteria,42ND0@68525|delta/epsilon subdivisions,2YP8U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF808)	-	-	-	ko:K09781	-	-	-	-	ko00000	-	-	-	DUF808
k59_62956_2	1249480.B649_02120	3.42e-71	235.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2YMW4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_415447_1	1348657.M622_00310	2.02e-95	290.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,2VHG3@28216|Betaproteobacteria,2KVM8@206389|Rhodocyclales	206389|Rhodocyclales	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
k59_1531905_1	563040.Saut_0660	1.22e-61	207.0	COG1283@1|root,COG1283@2|Bacteria,1MUDE@1224|Proteobacteria,42PW9@68525|delta/epsilon subdivisions,2YN4S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Na Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans
k59_708270_1	1537917.JU82_06840	1.48e-188	544.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,42MM9@68525|delta/epsilon subdivisions,2YMH2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
k59_6127_1	264198.Reut_A2982	1.89e-32	123.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,2VHAP@28216|Betaproteobacteria,1K01P@119060|Burkholderiaceae	28216|Betaproteobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
k59_6127_2	713586.KB900536_gene1377	6.62e-08	56.2	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,1RMGD@1236|Gammaproteobacteria,1WWTC@135613|Chromatiales	135613|Chromatiales	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_944324_1	572477.Alvin_0308	3.08e-14	79.3	COG2199@1|root,COG2202@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,1PGAZ@1224|Proteobacteria,1RWZ6@1236|Gammaproteobacteria,1X0SN@135613|Chromatiales	135613|Chromatiales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_9
k59_651511_1	1537917.JU82_06010	2.03e-84	253.0	COG2834@1|root,COG2834@2|Bacteria,1PQ15@1224|Proteobacteria,42WEH@68525|delta/epsilon subdivisions,2YPW1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
k59_534052_1	42565.FP66_05930	1.31e-79	249.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria,1XHB8@135619|Oceanospirillales	135619|Oceanospirillales	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metZ	-	-	ko:K10764	ko00270,ko00920,ko01100,map00270,map00920,map01100	-	R01288	RC00020,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
k59_1825558_1	326297.Sama_1640	1.25e-93	283.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1S2WF@1236|Gammaproteobacteria,2QA2H@267890|Shewanellaceae	1236|Gammaproteobacteria	C	PFAM iron-containing alcohol dehydrogenase	-	GO:0003674,GO:0003824,GO:0004022,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.1.3.48	ko:K19714	-	-	R11394	RC03427	ko00000,ko01000,ko01005	-	-	-	Fe-ADH
k59_1825558_2	94122.Shewana3_1908	9.98e-30	115.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,1S5KR@1236|Gammaproteobacteria,2QA4J@267890|Shewanellaceae	1236|Gammaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0016051,GO:0043170,GO:0044238,GO:0071704,GO:1901576	2.6.1.109	ko:K19715	-	-	R11395	RC00160	ko00000,ko01000,ko01005	-	-	-	DegT_DnrJ_EryC1
k59_1648323_1	1537917.JU82_06925	9.38e-190	535.0	COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,42MVB@68525|delta/epsilon subdivisions,2YNU4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	O-acetylhomoserine sulfhydrylase	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
k59_1648323_2	929558.SMGD1_0759	2.6e-49	164.0	COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,42SQE@68525|delta/epsilon subdivisions,2YPHI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	GO:0003674,GO:0003824,GO:0004141,GO:0016874,GO:0016879,GO:0016882	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
k59_885207_1	887062.HGR_00240	8.29e-57	180.0	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,2VR65@28216|Betaproteobacteria,4AB7W@80864|Comamonadaceae	28216|Betaproteobacteria	S	transferase hexapeptide	yrdA	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
k59_63007_2	709032.Sulku_1130	7.64e-44	147.0	COG0352@1|root,COG0352@2|Bacteria,1Q57E@1224|Proteobacteria,42T8S@68525|delta/epsilon subdivisions,2YPQM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Thiamine monophosphate synthase	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
k59_1060902_1	1249480.B649_02855	1.95e-278	783.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,42M9S@68525|delta/epsilon subdivisions,2YMAH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the ClpA ClpB family	clpB	-	-	ko:K03694,ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_1060902_2	1537917.JU82_03200	1.57e-129	372.0	COG2733@1|root,COG2733@2|Bacteria,1R4JT@1224|Proteobacteria,42RK1@68525|delta/epsilon subdivisions,2YPBZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1060902_3	1249480.B649_02845	1.28e-87	260.0	2AJNF@1|root,31A9U@2|Bacteria,1Q56P@1224|Proteobacteria,430NW@68525|delta/epsilon subdivisions,2YS38@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1592154_2	709032.Sulku_2008	3.12e-48	164.0	COG0446@1|root,COG0446@2|Bacteria,1QA17@1224|Proteobacteria,42P5E@68525|delta/epsilon subdivisions,2YN01@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Fad-dependent pyridine nucleotide-disulfide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_536825_1	1304883.KI912532_gene1091	3.64e-96	292.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,2VI67@28216|Betaproteobacteria,2KUT0@206389|Rhodocyclales	206389|Rhodocyclales	M	3-Deoxy-D-manno-octulosonic-acid transferase	-	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_1,Glycos_transf_N
k59_64947_2	1165841.SULAR_04282	6.46e-88	266.0	COG0158@1|root,COG0158@2|Bacteria,1MW0E@1224|Proteobacteria,42NRA@68525|delta/epsilon subdivisions,2YMJC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1	fbp	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
k59_1534523_1	522306.CAP2UW1_2223	6.95e-23	105.0	COG0784@1|root,COG5002@1|root,COG0784@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,2WGIN@28216|Betaproteobacteria,1KR9E@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
k59_1534523_2	929558.SMGD1_0387	3.49e-80	239.0	COG3829@1|root,COG3829@2|Bacteria,1RH32@1224|Proteobacteria,42RBS@68525|delta/epsilon subdivisions,2YTD0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	PAS fold	-	-	-	ko:K03776	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	PAS_3
k59_124957_1	56780.SYN_01058	1.17e-81	266.0	COG4206@1|root,COG4206@2|Bacteria,1R8Q7@1224|Proteobacteria,43BPB@68525|delta/epsilon subdivisions,2WKBT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug
k59_594204_1	159087.Daro_0046	1.01e-115	363.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2VHYQ@28216|Betaproteobacteria,2KUFA@206389|Rhodocyclales	206389|Rhodocyclales	H	methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
k59_1298046_1	1537917.JU82_01790	1.3e-48	159.0	2AJZN@1|root,31ANZ@2|Bacteria,1Q5WH@1224|Proteobacteria,42UJ4@68525|delta/epsilon subdivisions,2YPXB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1298046_2	709032.Sulku_2289	2.73e-65	211.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,42NKY@68525|delta/epsilon subdivisions,2YN43@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
k59_1650761_1	760154.Sulba_1889	2.06e-09	58.2	COG1216@1|root,COG1216@2|Bacteria,1QU2Q@1224|Proteobacteria,43BK5@68525|delta/epsilon subdivisions,2YN4Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
k59_1650761_2	1537917.JU82_07440	5.62e-63	200.0	COG0515@1|root,COG0515@2|Bacteria,1R91D@1224|Proteobacteria,42XMS@68525|delta/epsilon subdivisions,2YT4X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KLT	Lipopolysaccharide kinase (Kdo/WaaP) family	-	-	-	-	-	-	-	-	-	-	-	-	Kdo
k59_124983_1	1162668.LFE_0928	2.65e-06	53.9	COG0845@1|root,COG0845@2|Bacteria,3J15F@40117|Nitrospirae	40117|Nitrospirae	M	HlyD family secretion protein	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
k59_124983_2	387093.SUN_0273	2.95e-29	115.0	COG1538@1|root,COG1538@2|Bacteria,1PBTH@1224|Proteobacteria,42R59@68525|delta/epsilon subdivisions,2YP2M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_1416355_1	1249480.B649_05070	1.3e-44	156.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2YNK5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DEAD box helicase family	dbpA	-	3.6.4.13	ko:K05591	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DEAD,DbpA,Helicase_C
k59_1063324_1	1537917.JU82_11565	1.73e-94	281.0	COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,42R60@68525|delta/epsilon subdivisions,2YNZM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_1474772_2	709032.Sulku_1310	1.26e-75	241.0	COG1956@1|root,COG3604@1|root,COG1956@2|Bacteria,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,42Y69@68525|delta/epsilon subdivisions,2YNEN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	Transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF_2,HTH_8,Sigma54_activat
k59_299547_1	387092.NIS_1717	3.86e-84	270.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,42PUI@68525|delta/epsilon subdivisions,2YN3E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	PFAM TrkA-N domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2,TrkA_N
k59_536908_1	90813.JQMT01000001_gene1087	1.77e-107	322.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,1RMAK@1236|Gammaproteobacteria,45ZSN@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
k59_1063349_1	1249480.B649_05825	1.31e-50	175.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,42N7A@68525|delta/epsilon subdivisions,2YMRE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	lytic murein transglycosylase	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
k59_1063349_2	1537917.JU82_08235	3.53e-44	145.0	COG0762@1|root,COG0762@2|Bacteria,1QDB9@1224|Proteobacteria,42VCU@68525|delta/epsilon subdivisions,2YQ8B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
k59_1063349_3	1537917.JU82_08240	7.53e-82	254.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,42NHA@68525|delta/epsilon subdivisions,2YMYU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX1	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
k59_947079_1	1442598.JABW01000001_gene1819	5.94e-67	225.0	COG0715@1|root,COG2199@1|root,COG0715@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42MCD@68525|delta/epsilon subdivisions,2YN6K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	ET	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,NMT1,SBP_bac_3
k59_1650828_1	929558.SMGD1_2071	3.3e-61	205.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42S84@68525|delta/epsilon subdivisions,2YPD4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_8,dCache_3
k59_1416404_1	929556.Solca_2594	2.36e-55	192.0	COG4948@1|root,COG4948@2|Bacteria,4PKP3@976|Bacteroidetes,1IRBT@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyl-hydrolase 97 N-terminal	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	GH97_C,GH97_N,Glyco_hydro_97,Lipase_GDSL_2
k59_65036_1	273121.WS0630	5.9e-30	107.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,42V9M@68525|delta/epsilon subdivisions,2YPX3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
k59_65036_2	1249480.B649_01645	4.19e-64	201.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,42MB9@68525|delta/epsilon subdivisions,2YMN0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	IQ	reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_906320_2	709032.Sulku_2298	6.93e-117	345.0	COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,42MGS@68525|delta/epsilon subdivisions,2YMUK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
k59_616309_1	583345.Mmol_1541	7.3e-105	310.0	COG0714@1|root,COG0714@2|Bacteria,1MUCP@1224|Proteobacteria,2VN99@28216|Betaproteobacteria,2KM2B@206350|Nitrosomonadales	206350|Nitrosomonadales	S	PFAM ATPase associated with various cellular activities, AAA_3	-	-	-	-	-	-	-	-	-	-	-	-	AAA_3
k59_1376475_1	563040.Saut_0847	5.44e-82	273.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YMMN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_790145_1	159087.Daro_3409	1.76e-83	261.0	2CG4C@1|root,2Z8MQ@2|Bacteria,1R6PQ@1224|Proteobacteria,2VHKG@28216|Betaproteobacteria,2KVNU@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_375901_1	1165841.SULAR_08075	3.02e-107	319.0	COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,1MVUS@1224|Proteobacteria,42NB7@68525|delta/epsilon subdivisions,2YMZH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
k59_906350_1	1537917.JU82_08025	1.74e-55	172.0	COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,42U8W@68525|delta/epsilon subdivisions,2YPVK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Ferredoxin	fdxB	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4
k59_1786761_1	1249480.B649_01570	1.39e-181	516.0	COG0507@1|root,COG0507@2|Bacteria,1QCFP@1224|Proteobacteria,42NH5@68525|delta/epsilon subdivisions,2YMK5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member	-	-	-	-	-	-	-	-	-	-	-	-	Herpes_Helicase,PIF1
k59_1670094_1	709032.Sulku_0794	8.28e-103	317.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42UBD@68525|delta/epsilon subdivisions,2YRGP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	7TM diverse intracellular signalling	-	-	-	ko:K20971	ko02025,map02025	-	-	-	ko00000,ko00001,ko01001,ko02022	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c
k59_1440480_1	159087.Daro_1055	8.57e-98	305.0	COG4774@1|root,COG4774@2|Bacteria,1MV0X@1224|Proteobacteria,2VIQR@28216|Betaproteobacteria,2KVX3@206389|Rhodocyclales	206389|Rhodocyclales	P	receptor	-	-	-	ko:K16090	-	-	-	-	ko00000,ko02000	1.B.14.1.11	-	-	Plug,TonB_dep_Rec
k59_147012_1	709032.Sulku_1511	7.12e-116	359.0	COG2199@1|root,COG2200@1|root,COG3287@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,COG3287@2|Bacteria,1NQKX@1224|Proteobacteria,43DAG@68525|delta/epsilon subdivisions,2YTHK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,FIST,FIST_C,GGDEF,PAS_9
k59_616387_1	796620.VIBC2010_09407	2.58e-07	57.4	COG0784@1|root,COG1776@1|root,COG0784@2|Bacteria,COG1776@2|Bacteria,1P5BV@1224|Proteobacteria,1RN5X@1236|Gammaproteobacteria,1XUEQ@135623|Vibrionales	135623|Vibrionales	T	COG0784 FOG CheY-like receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_1084269_1	1249480.B649_08865	5.26e-113	344.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,42M6W@68525|delta/epsilon subdivisions,2YN2C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	spoT	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT,HD_4,RelA_SpoT,TGS
k59_315345_1	1249480.B649_09270	7.28e-133	407.0	COG1305@1|root,COG4196@1|root,COG1305@2|Bacteria,COG4196@2|Bacteria,1MVAG@1224|Proteobacteria,42P26@68525|delta/epsilon subdivisions,2YN89@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Putative amidoligase enzyme (DUF2126)	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,DUF2126,Transglut_core
k59_677892_1	160488.PP_2283	1.21e-41	144.0	2ATMD@1|root,31J5V@2|Bacteria,1RH31@1224|Proteobacteria,1SPN9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Tail tubular protein	-	-	-	-	-	-	-	-	-	-	-	-	Tube
k59_1031775_1	1537917.JU82_10755	6.3e-130	377.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,42NNS@68525|delta/epsilon subdivisions,2YMQW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
k59_1031775_2	1537917.JU82_10760	2.31e-25	99.8	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,42PQP@68525|delta/epsilon subdivisions,2YNQ7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	abc transporter atp-binding protein	ybbA	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_677899_1	1208583.COMX_08680	1.76e-71	242.0	COG1629@1|root,COG4771@2|Bacteria,1MW7D@1224|Proteobacteria,2TS7D@28211|Alphaproteobacteria,2JU6N@204441|Rhodospirillales	204441|Rhodospirillales	P	TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_499243_1	556268.OFAG_01510	2.97e-19	85.9	COG0583@1|root,COG0583@2|Bacteria,1MVHT@1224|Proteobacteria,2VHF0@28216|Betaproteobacteria,472VT@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	LysR substrate binding domain	nhaR	-	-	ko:K03717	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k59_499243_2	768671.ThimaDRAFT_4734	4.41e-39	143.0	COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,1RPSM@1236|Gammaproteobacteria,1WW9T@135613|Chromatiales	135613|Chromatiales	P	PFAM Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
k59_1493716_1	709032.Sulku_2143	1.6e-12	66.2	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,42MBC@68525|delta/epsilon subdivisions,2YMZG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	hldE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
k59_1493716_2	1249480.B649_10095	9.4e-80	240.0	2ANX8@1|root,31DXW@2|Bacteria,1QB8A@1224|Proteobacteria,42WEI@68525|delta/epsilon subdivisions,2YQAD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	YfaZ
k59_81073_1	159087.Daro_0391	1.47e-14	73.6	COG3501@1|root,COG4253@1|root,COG3501@2|Bacteria,COG4253@2|Bacteria,1MU7Q@1224|Proteobacteria,2VJSR@28216|Betaproteobacteria,2M01Y@206389|Rhodocyclales	206389|Rhodocyclales	S	Uncharacterized protein conserved in bacteria (DUF2345)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2345,Phage_GPD,T6SS_Vgr
k59_81073_2	159087.Daro_2185	1.65e-40	143.0	COG3515@1|root,COG3515@2|Bacteria,1MY80@1224|Proteobacteria,2VN8Y@28216|Betaproteobacteria,2KWPV@206389|Rhodocyclales	206389|Rhodocyclales	S	ImpA, N-terminal, type VI secretion system	-	-	-	ko:K11902	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	ImpA_N
k59_81076_1	1537917.JU82_08630	2.99e-32	125.0	COG0715@1|root,COG0834@1|root,COG2199@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42UTN@68525|delta/epsilon subdivisions,2YTHQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EPT	NMT1/THI5 like	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	GGDEF,NMT1,SBP_bac_3
k59_24208_1	1249480.B649_01370	3.71e-96	290.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,42PFG@68525|delta/epsilon subdivisions,2YN2E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1252 NADH dehydrogenase FAD-containing subunit	ndh	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_1376572_1	1249480.B649_07285	8.07e-115	344.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,42M81@68525|delta/epsilon subdivisions,2YMTF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_499275_1	709032.Sulku_1633	2.14e-113	338.0	COG2206@1|root,COG2206@2|Bacteria,1R53C@1224|Proteobacteria,42R7P@68525|delta/epsilon subdivisions,2YPRS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
k59_906431_1	395494.Galf_0573	1.09e-96	284.0	COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,2VQ4W@28216|Betaproteobacteria,44VQK@713636|Nitrosomonadales	28216|Betaproteobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
k59_1786842_1	1165841.SULAR_05998	6.47e-78	239.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,42RTC@68525|delta/epsilon subdivisions,2YP4A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
k59_1786842_2	1165841.SULAR_06003	6.88e-07	49.7	COG2863@1|root,COG2863@2|Bacteria,1PFA2@1224|Proteobacteria,42XJ8@68525|delta/epsilon subdivisions,2YQVM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	cytochrome c class I	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
k59_499289_1	717772.THIAE_07685	3.99e-71	233.0	COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,1RNWD@1236|Gammaproteobacteria,4600N@72273|Thiotrichales	72273|Thiotrichales	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
k59_906436_1	1537917.JU82_09900	6.79e-67	213.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,42MMG@68525|delta/epsilon subdivisions,2YMCT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
k59_260939_1	1502770.JQMG01000001_gene146	1.88e-150	431.0	COG2890@1|root,COG2890@2|Bacteria,1MV12@1224|Proteobacteria,2VJVT@28216|Betaproteobacteria,2KM2Z@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Putative RNA methylase family UPF0020	-	-	-	-	-	-	-	-	-	-	-	-	MTS
k59_1199613_2	1537917.JU82_04395	1.56e-28	110.0	COG1580@1|root,COG1580@2|Bacteria,1NBUX@1224|Proteobacteria,42RSV@68525|delta/epsilon subdivisions,2YPAW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Controls the rotational direction of flagella during chemotaxis	fliL	-	-	ko:K02415	-	-	-	-	ko00000,ko02035	-	-	-	FliL
k59_202391_1	1114959.SZMC14600_11343	1.91e-06	49.3	COG1191@1|root,COG1191@2|Bacteria,2GKBK@201174|Actinobacteria,4DZK1@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	whiG	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_1084333_1	90813.JQMT01000001_gene1374	6.69e-113	340.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,1RMWE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	GO:0003674,GO:0003824,GO:0003852,GO:0003985,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046912,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iSFV_1184.SFV_0066	HMGL-like,LeuA_dimer
k59_1786868_1	159087.Daro_2985	1.4e-122	359.0	COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,2VID7@28216|Betaproteobacteria,2KUBR@206389|Rhodocyclales	206389|Rhodocyclales	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
k59_202431_1	1304883.KI912532_gene1908	2.29e-83	255.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,2VHIP@28216|Betaproteobacteria,2KVAZ@206389|Rhodocyclales	206389|Rhodocyclales	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
k59_1265142_1	1537917.JU82_06795	5.17e-73	236.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42NK1@68525|delta/epsilon subdivisions,2YMHN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the AAA ATPase family	ftsH1	-	-	-	-	-	-	-	-	-	-	-	AAA,Peptidase_M41
k59_678024_1	1392502.JNIO01000008_gene1585	6.09e-32	120.0	COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,4H56U@909932|Negativicutes	909932|Negativicutes	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
k59_1031940_1	709032.Sulku_0641	7.14e-107	314.0	COG3301@1|root,COG3301@2|Bacteria,1QSRQ@1224|Proteobacteria,42PAY@68525|delta/epsilon subdivisions,2YN5Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
k59_315447_1	159087.Daro_0902	1.93e-125	366.0	COG1960@1|root,COG1960@2|Bacteria,1MXMQ@1224|Proteobacteria,2VNPR@28216|Betaproteobacteria,2KYMQ@206389|Rhodocyclales	206389|Rhodocyclales	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.14.14.12	ko:K16047	ko00984,ko01100,ko01120,map00984,map01100,map01120	-	R09819	RC00236	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_2,Acyl-CoA_dh_N
k59_1558256_1	1211114.ALIP01000160_gene1603	1.23e-49	179.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,1RMK0@1236|Gammaproteobacteria,1X3ME@135614|Xanthomonadales	135614|Xanthomonadales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_616609_1	292415.Tbd_2613	1.16e-84	261.0	COG0730@1|root,COG0730@2|Bacteria	2|Bacteria	S	response to heat	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE,Usp
k59_616610_1	640081.Dsui_0799	4.73e-40	145.0	COG0427@1|root,COG0427@2|Bacteria,1MUGE@1224|Proteobacteria,2VJUB@28216|Betaproteobacteria,2KVMY@206389|Rhodocyclales	206389|Rhodocyclales	C	acetyl-CoA hydrolase	cat1	-	2.8.3.18	ko:K18118	ko00020,ko00620,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00650,map01100,map01110,map01120,map01130,map01200	M00009,M00011	R10343	RC00012,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
k59_261038_1	1249480.B649_05730	7.05e-119	347.0	COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,42R55@68525|delta/epsilon subdivisions,2YNS0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
k59_499442_2	1249480.B649_00170	2.53e-57	186.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,42M8N@68525|delta/epsilon subdivisions,2YMFN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	hprA	-	1.1.1.29	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	M00346	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
k59_1199720_1	159087.Daro_3022	2.83e-133	386.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VH4C@28216|Betaproteobacteria,2KVUF@206389|Rhodocyclales	206389|Rhodocyclales	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k59_262655_1	666681.M301_2444	4.14e-114	344.0	COG1807@1|root,COG1807@2|Bacteria,1PUE3@1224|Proteobacteria,2VHPU@28216|Betaproteobacteria,2KMGR@206350|Nitrosomonadales	206350|Nitrosomonadales	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
k59_971148_1	580332.Slit_2909	1.5e-66	210.0	COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,2VHA6@28216|Betaproteobacteria,44VIN@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
k59_1378307_1	1537917.JU82_03925	2.58e-121	364.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42MBE@68525|delta/epsilon subdivisions,2YNGN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	abc transporter atp-binding protein	-	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k59_1730489_1	263820.PTO1214	8.61e-59	196.0	COG0017@1|root,arCOG00406@2157|Archaea,2XTRE@28890|Euryarchaeota,241JY@183967|Thermoplasmata	183967|Thermoplasmata	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.23	ko:K09759	ko00970,map00970	M00360	R03647,R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k59_563292_1	159087.Daro_2824	1.54e-104	321.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,2VHH8@28216|Betaproteobacteria,2KUJF@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
k59_262668_1	358220.C380_15660	3.7e-134	397.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VIP3@28216|Betaproteobacteria,4AARI@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k59_792876_1	159087.Daro_3128	4.02e-111	334.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,2VK5J@28216|Betaproteobacteria,2KX6U@206389|Rhodocyclales	206389|Rhodocyclales	F	5'-nucleotidase, C-terminal domain	-	-	3.1.3.5,3.6.1.45	ko:K01081,ko:K11751,ko:K17224	ko00230,ko00240,ko00760,ko00920,ko01100,ko01110,ko01120,map00230,map00240,map00760,map00920,map01100,map01110,map01120	M00595	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R10151	RC00017,RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	-	-	-	5_nucleotid_C,Metallophos
k59_792876_2	1121035.AUCH01000007_gene467	1.57e-43	146.0	COG2010@1|root,COG2010@2|Bacteria,1P1GY@1224|Proteobacteria,2VP4W@28216|Betaproteobacteria,2KYRD@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome c	-	-	-	ko:K17223	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	-
k59_501676_1	640081.Dsui_0418	2.48e-70	222.0	COG0385@1|root,COG0385@2|Bacteria,1MUMM@1224|Proteobacteria,2VI94@28216|Betaproteobacteria,2KW5I@206389|Rhodocyclales	206389|Rhodocyclales	S	Na -dependent transporter	-	-	-	ko:K14347	-	-	-	-	ko00000,ko02000,ko04147	2.A.93.1	-	-	SBF_like
k59_1148318_1	1537917.JU82_01995	6.76e-123	351.0	COG1014@1|root,COG1014@2|Bacteria,1N12F@1224|Proteobacteria,42NN1@68525|delta/epsilon subdivisions,2YN1Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	pyruvate ferredoxin oxidoreductase	porC	-	1.2.7.1	ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
k59_204727_1	123214.PERMA_1456	1.66e-104	316.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
k59_316744_2	1249480.B649_05405	1.42e-133	389.0	COG2199@1|root,COG3829@1|root,COG3706@2|Bacteria,COG3829@2|Bacteria,1R7HC@1224|Proteobacteria,42YVM@68525|delta/epsilon subdivisions,2YRBE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_9
k59_148617_1	525898.Sdel_1079	1.5e-56	196.0	COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,42M9U@68525|delta/epsilon subdivisions,2YNJP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	RNA binding S1 domain protein	-	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
k59_148617_2	709032.Sulku_1810	1.37e-37	128.0	COG3326@1|root,COG3326@2|Bacteria	2|Bacteria	L	Membrane	ysdA	-	-	-	-	-	-	-	-	-	-	-	CSD,DUF1294
k59_204752_1	159087.Daro_2907	8.4e-105	315.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,2VQUN@28216|Betaproteobacteria,2KWBB@206389|Rhodocyclales	206389|Rhodocyclales	T	signal transduction protein containing EAL and modified HD-GYP domains	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_1442924_1	159087.Daro_0255	1.08e-120	354.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,2VHRJ@28216|Betaproteobacteria,2KUZ8@206389|Rhodocyclales	206389|Rhodocyclales	H	Coenzyme F390 synthetase	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding
k59_1495410_1	709032.Sulku_1071	1.57e-103	314.0	COG0702@1|root,COG0702@2|Bacteria,1PDTN@1224|Proteobacteria,42M8X@68525|delta/epsilon subdivisions,2YM7Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
k59_1086122_1	535289.Dtpsy_1802	9.08e-25	104.0	COG4275@1|root,COG4275@2|Bacteria,1MYDE@1224|Proteobacteria,2VKAX@28216|Betaproteobacteria,4ADUB@80864|Comamonadaceae	28216|Betaproteobacteria	S	Chromate resistance exported protein	chrB	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
k59_1148398_1	1450525.JATV01000006_gene851	2.25e-29	120.0	COG5492@1|root,COG5492@2|Bacteria,4NHPH@976|Bacteroidetes,1HZ96@117743|Flavobacteriia,2NTQH@237|Flavobacterium	976|Bacteroidetes	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_680254_1	582744.Msip34_1203	2.95e-153	441.0	COG0160@1|root,COG0160@2|Bacteria,1QTZ3@1224|Proteobacteria,2VHZE@28216|Betaproteobacteria,2KNKT@206350|Nitrosomonadales	206350|Nitrosomonadales	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
k59_1612553_1	1537917.JU82_09485	1.62e-112	334.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,42MGM@68525|delta/epsilon subdivisions,2YMUV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
k59_971275_1	1408312.JNJS01000001_gene1268	8.52e-25	108.0	COG0642@1|root,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,3NHZ0@46205|Pseudobutyrivibrio	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,MASE3,Reg_prop,Response_reg
k59_262762_1	1121920.AUAU01000014_gene2790	1.96e-21	86.3	2EK70@1|root,33DXD@2|Bacteria,3Y5QD@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_262762_2	1123400.KB904747_gene510	7.87e-09	56.2	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,1RPQ7@1236|Gammaproteobacteria,45ZQK@72273|Thiotrichales	72273|Thiotrichales	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
k59_680275_1	1537917.JU82_10865	1.18e-159	462.0	COG0464@1|root,COG0464@2|Bacteria,1N4ZI@1224|Proteobacteria,42NGJ@68525|delta/epsilon subdivisions,2YMAX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	ATPase (AAA	-	-	-	-	-	-	-	-	-	-	-	-	AAA
k59_501751_1	580332.Slit_0155	7.96e-121	357.0	COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,2VIJH@28216|Betaproteobacteria,44WG4@713636|Nitrosomonadales	28216|Betaproteobacteria	P	NMT1-like family	nasF	-	-	ko:K02051,ko:K15576,ko:K22067	ko00910,ko02010,map00910,map02010	M00188,M00438	-	-	ko00000,ko00001,ko00002,ko02000,ko02022	3.A.1.16,3.A.1.16.1,3.A.1.16.2,3.A.1.17	-	-	NMT1_2
k59_1854032_1	395494.Galf_1821	3.08e-113	334.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2VH4Z@28216|Betaproteobacteria,44V1P@713636|Nitrosomonadales	28216|Betaproteobacteria	E	PFAM aminotransferase class I and II	alaA	-	2.6.1.2,2.6.1.66	ko:K14260	ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230	-	R00258,R01215	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_501758_1	159087.Daro_0665	4.18e-56	189.0	COG1274@1|root,COG1274@2|Bacteria,1MX3C@1224|Proteobacteria,2VINZ@28216|Betaproteobacteria,2KV5X@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
k59_148696_2	1123518.ARWI01000001_gene1266	3.87e-49	162.0	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,1RPB6@1236|Gammaproteobacteria,460M5@72273|Thiotrichales	72273|Thiotrichales	S	Bacterial transferase hexapeptide	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
k59_793040_1	159087.Daro_2112	3.54e-46	154.0	COG2071@1|root,COG2071@2|Bacteria,1MV8E@1224|Proteobacteria,2VMMI@28216|Betaproteobacteria,2KW7J@206389|Rhodocyclales	206389|Rhodocyclales	S	Peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
k59_377594_2	1249480.B649_04090	6.39e-65	216.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1R5RS@1224|Proteobacteria,42M3K@68525|delta/epsilon subdivisions,2YN6E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	PFAM biotin lipoyl attachment domain-containing protein	pycB	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
k59_1086203_1	760192.Halhy_2202	6.84e-40	151.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,4NEK3@976|Bacteroidetes,1IPPB@117747|Sphingobacteriia	976|Bacteroidetes	C	FAD linked oxidases, C-terminal domain	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_8
k59_680356_1	929558.SMGD1_2878	1.79e-07	58.5	COG1376@1|root,COG2931@1|root,COG1376@2|Bacteria,COG2931@2|Bacteria,1PGYM@1224|Proteobacteria,42YEY@68525|delta/epsilon subdivisions,2YRCA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1443077_1	929558.SMGD1_2835	1.51e-54	186.0	COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,42PV5@68525|delta/epsilon subdivisions,2YMVK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
k59_850658_1	1198452.Jab_2c19650	3.61e-45	169.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,2VI2R@28216|Betaproteobacteria,4730W@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	extracellular alpha-helical protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1
k59_1672080_2	1249480.B649_10665	4.84e-55	177.0	COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,42N66@68525|delta/epsilon subdivisions,2YMY7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate	ate	-	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	ATE_C,ATE_N
k59_463380_1	1268237.G114_01479	3.2e-05	45.8	COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,1S3QR@1236|Gammaproteobacteria,1Y4ES@135624|Aeromonadales	135624|Aeromonadales	O	Peptidyl-prolyl cis-trans	slyD	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
k59_463380_2	999141.GME_15550	2.67e-58	187.0	COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,1RNHQ@1236|Gammaproteobacteria,1XHX2@135619|Oceanospirillales	135619|Oceanospirillales	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_463389_1	1537917.JU82_03980	3.34e-10	59.3	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,42MJY@68525|delta/epsilon subdivisions,2YMA5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
k59_463389_2	1537917.JU82_03985	8.43e-193	539.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,42MCP@68525|delta/epsilon subdivisions,2YMQE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
k59_748366_1	709032.Sulku_0949	1.48e-191	547.0	COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42PMU@68525|delta/epsilon subdivisions,2YNHE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4
k59_748366_3	1537917.JU82_06290	8.38e-60	192.0	COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,42NRG@68525|delta/epsilon subdivisions,2YN78@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase,Glycos_trans_3N,Glycos_transf_3
k59_645248_1	1449049.JONW01000010_gene3507	1.26e-09	62.0	COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,2U79T@28211|Alphaproteobacteria,2KGHI@204458|Caulobacterales	204458|Caulobacterales	G	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress	gph	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_645248_3	1401065.HMPREF2130_04615	0.000622	46.2	COG1434@1|root,COG1434@2|Bacteria,1MVW8@1224|Proteobacteria,2VSH4@28216|Betaproteobacteria,3T2TQ@506|Alcaligenaceae	28216|Betaproteobacteria	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
k59_1696678_1	1537917.JU82_07305	4.41e-76	252.0	COG2202@1|root,COG4191@1|root,COG4585@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,COG4585@2|Bacteria,1PFGC@1224|Proteobacteria,42Z6H@68525|delta/epsilon subdivisions,2YRF4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,HATPase_c,PAS_9
k59_1343836_1	990073.ATHU01000001_gene914	4.36e-81	248.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,42M44@68525|delta/epsilon subdivisions,2YMH6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth,NMO
k59_1403811_1	1249480.B649_04295	1.44e-28	108.0	COG0723@1|root,COG0723@2|Bacteria,1MZ7A@1224|Proteobacteria,42N9F@68525|delta/epsilon subdivisions,2YNBZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
k59_1403811_2	1249480.B649_04300	1.1e-62	195.0	2BQ12@1|root,319E3@2|Bacteria,1Q2GE@1224|Proteobacteria,42VNB@68525|delta/epsilon subdivisions,2YQEY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1111665_1	1537917.JU82_04615	3.67e-65	201.0	COG0711@1|root,COG0711@2|Bacteria,1Q2G9@1224|Proteobacteria,42VN4@68525|delta/epsilon subdivisions,2YQBE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the ATPase B chain family	atpF'	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
k59_1111665_2	709032.Sulku_0755	1.95e-84	253.0	COG0711@1|root,COG0711@2|Bacteria,1Q9TP@1224|Proteobacteria,42U87@68525|delta/epsilon subdivisions,2YPT1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
k59_1111686_1	387093.SUN_0787	2.79e-24	103.0	COG0642@1|root,COG0642@2|Bacteria,1QTSX@1224|Proteobacteria,43CMA@68525|delta/epsilon subdivisions,2YRH0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c
k59_748487_1	1537917.JU82_01740	4.52e-165	470.0	COG0387@1|root,COG0387@2|Bacteria,1N1MR@1224|Proteobacteria,42MUQ@68525|delta/epsilon subdivisions,2YMUB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Sodium calcium exchanger membrane	-	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
k59_1403875_2	709032.Sulku_0977	1.15e-47	162.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,42M5Y@68525|delta/epsilon subdivisions,2YMJB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
k59_1640603_1	608534.GCWU000341_01964	1.1e-05	53.1	COG0463@1|root,COG0463@2|Bacteria,1V2EP@1239|Firmicutes,24GAY@186801|Clostridia,2PRNZ@265975|Oribacterium	186801|Clostridia	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_748497_1	1538295.JY96_05440	4.1e-92	293.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,2WGU7@28216|Betaproteobacteria,1KPG2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_525880_3	1537917.JU82_09805	1.47e-113	330.0	2AIM2@1|root,302EJ@2|Bacteria,1Q99E@1224|Proteobacteria,42ZJ9@68525|delta/epsilon subdivisions,2YRN3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_525880_4	1249480.B649_03090	1.96e-93	277.0	2A4ZC@1|root,30TM8@2|Bacteria,1PDIE@1224|Proteobacteria,42X6N@68525|delta/epsilon subdivisions,2YRSB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_525904_2	159087.Daro_0544	9.8e-98	308.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,2VH2J@28216|Betaproteobacteria,2KV8K@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
k59_1757579_1	338969.Rfer_0458	9.94e-94	303.0	COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,4A9PA@80864|Comamonadaceae	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GAF_2,GGDEF,PAS,PAS_4,PAS_9,SBP_bac_3
k59_937464_2	709032.Sulku_2480	4.34e-143	413.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,42N75@68525|delta/epsilon subdivisions,2YNFC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Metallophosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
k59_1757591_1	1165841.SULAR_09614	6.53e-120	355.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,42M7A@68525|delta/epsilon subdivisions,2YNCK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k59_341723_1	1249480.B649_09285	2.97e-67	213.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria	1224|Proteobacteria	T	Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HD,HD_5
k59_341723_2	1249480.B649_09290	1.45e-22	93.6	2CHQX@1|root,33W06@2|Bacteria,1NWMC@1224|Proteobacteria,42V4N@68525|delta/epsilon subdivisions	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_525931_2	877424.ATWC01000019_gene1022	2.93e-12	67.8	COG2206@1|root,COG2206@2|Bacteria,1TR95@1239|Firmicutes,25AZS@186801|Clostridia,27K6D@186928|unclassified Lachnospiraceae	186801|Clostridia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
k59_645499_1	317025.Tcr_1570	1.98e-105	317.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,1RM7N@1236|Gammaproteobacteria,45ZPH@72273|Thiotrichales	72273|Thiotrichales	H	PFAM aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_1404022_2	709032.Sulku_0083	1.45e-42	146.0	COG1639@1|root,COG1639@2|Bacteria,1RAH3@1224|Proteobacteria,42PRF@68525|delta/epsilon subdivisions,2YMRX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Signal transduction protein	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_1227135_1	317025.Tcr_0212	1.97e-09	59.3	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,4603G@72273|Thiotrichales	72273|Thiotrichales	L	it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction	rep	-	3.6.4.12	ko:K03656	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_1227135_2	383407.XOC_0451	6.61e-46	159.0	COG2899@1|root,COG2899@2|Bacteria,1NURT@1224|Proteobacteria,1RQ9S@1236|Gammaproteobacteria,1X5WD@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF475)	-	-	-	ko:K09799	-	-	-	-	ko00000	-	-	-	DUF475
k59_49217_1	1537917.JU82_10965	3e-48	162.0	2AI7Y@1|root,318NF@2|Bacteria,1Q0NR@1224|Proteobacteria,42SAU@68525|delta/epsilon subdivisions,2YPMQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1404076_2	1249480.B649_01035	1.42e-51	177.0	COG0745@1|root,COG0745@2|Bacteria,1QXJT@1224|Proteobacteria,42V47@68525|delta/epsilon subdivisions,2YQ8S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	RESPONSE REGULATOR receiver	-	-	-	ko:K07288	-	-	-	-	ko00000	-	-	-	-
k59_1111919_2	1249480.B649_07260	1.74e-52	170.0	2AJE1@1|root,319ZU@2|Bacteria,1Q4J6@1224|Proteobacteria,42U7R@68525|delta/epsilon subdivisions,2YQ63@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_645591_1	644107.SL1157_1212	1.24e-32	125.0	COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,2TR2Q@28211|Alphaproteobacteria,4NAQT@97050|Ruegeria	28211|Alphaproteobacteria	V	ABC transporter, ATP-binding protein	yadG	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_645591_2	90814.KL370891_gene511	2.46e-92	280.0	COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,1RP0Z@1236|Gammaproteobacteria,46014@72273|Thiotrichales	72273|Thiotrichales	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
k59_526025_1	709032.Sulku_0705	8.64e-85	268.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42MS0@68525|delta/epsilon subdivisions,2YMTX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_1111938_1	580332.Slit_1748	7.81e-85	274.0	COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,2VHHQ@28216|Betaproteobacteria,44VBM@713636|Nitrosomonadales	28216|Betaproteobacteria	Q	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_403115_1	709032.Sulku_0534	3.48e-30	108.0	COG2929@1|root,COG2929@2|Bacteria,1N6QP@1224|Proteobacteria,42VMA@68525|delta/epsilon subdivisions,2YQAI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
k59_288846_1	709032.Sulku_1842	3.7e-51	172.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,42MWJ@68525|delta/epsilon subdivisions,2YM9G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
k59_1349935_2	1121374.KB891589_gene113	1.38e-34	132.0	COG1232@1|root,COG1232@2|Bacteria,1QTUF@1224|Proteobacteria,1SH58@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	NAD(P)-binding Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8
k59_1817865_1	1249480.B649_07945	9.12e-38	142.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K13040,ko:K20971	ko02020,ko02025,map02020,map02025	M00514	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,NMT1,PAS_4,PAS_9,SBP_bac_3
k59_409223_1	709032.Sulku_1035	2.2e-43	145.0	COG2353@1|root,COG2353@2|Bacteria,1N4PP@1224|Proteobacteria,42U5U@68525|delta/epsilon subdivisions,2YQF5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
k59_348592_2	933262.AXAM01000005_gene2537	2.97e-34	125.0	COG1344@1|root,COG1344@2|Bacteria,1MXC4@1224|Proteobacteria,42RME@68525|delta/epsilon subdivisions,2WN9Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	PFAM flagellin domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Flagellin_C,Flagellin_N
k59_409224_1	1123393.KB891333_gene2622	1.7e-55	182.0	COG0672@1|root,COG0672@2|Bacteria,1MX1M@1224|Proteobacteria,2VHEE@28216|Betaproteobacteria,1KRVC@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Iron permease FTR1 family	-	-	-	-	-	-	-	-	-	-	-	-	FTR1
k59_409224_2	748247.AZKH_4488	8.13e-48	155.0	COG4633@1|root,COG4633@2|Bacteria,1N6VB@1224|Proteobacteria,2WHPH@28216|Betaproteobacteria,2KZ5U@206389|Rhodocyclales	206389|Rhodocyclales	S	Cupredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
k59_754794_1	944547.ABLL_2828	3.01e-70	221.0	COG3907@1|root,COG3907@2|Bacteria,1MY7B@1224|Proteobacteria,42RAC@68525|delta/epsilon subdivisions,2YRS3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
k59_409280_1	640081.Dsui_3155	3.28e-115	337.0	COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,2VHPJ@28216|Betaproteobacteria,2KV1X@206389|Rhodocyclales	206389|Rhodocyclales	G	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component	-	-	-	ko:K11688	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctP
k59_53552_1	1537917.JU82_07065	1.5e-127	364.0	COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,42QX8@68525|delta/epsilon subdivisions,2YP1G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
k59_348727_1	1165841.SULAR_02653	2.05e-59	202.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42NK1@68525|delta/epsilon subdivisions,2YMHN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the AAA ATPase family	ftsH1	-	-	-	-	-	-	-	-	-	-	-	AAA,Peptidase_M41
k59_879547_1	1165841.SULAR_03572	2.58e-115	341.0	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,42MSF@68525|delta/epsilon subdivisions,2YNA7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	alanine dehydrogenase	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
k59_293502_1	1537917.JU82_07035	2.61e-142	412.0	COG1168@1|root,COG1168@2|Bacteria,1MY33@1224|Proteobacteria,42M6F@68525|delta/epsilon subdivisions,2YMXE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Aminotransferase, class I	patB	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_348743_2	709032.Sulku_2417	1.13e-14	72.4	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,42N3P@68525|delta/epsilon subdivisions,2YM8F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EG	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
k59_879617_1	598659.NAMH_0970	2.2e-64	213.0	COG2211@1|root,COG2211@2|Bacteria,1MWSH@1224|Proteobacteria	1224|Proteobacteria	G	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	BT1
k59_1526013_1	317025.Tcr_1150	2.76e-74	258.0	COG2202@1|root,COG2203@1|root,COG5001@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,45ZZR@72273|Thiotrichales	72273|Thiotrichales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_9
k59_754990_1	1537917.JU82_09120	1.84e-141	429.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,42MGK@68525|delta/epsilon subdivisions,2YMHU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_1526054_1	497321.C664_19521	1.38e-35	130.0	COG3705@1|root,COG3705@2|Bacteria,1MWIG@1224|Proteobacteria,2VHVX@28216|Betaproteobacteria,2KUII@206389|Rhodocyclales	206389|Rhodocyclales	E	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
k59_1526054_2	159087.Daro_2976	3.71e-31	109.0	COG3242@1|root,COG3242@2|Bacteria,1NG9Q@1224|Proteobacteria,2VXNJ@28216|Betaproteobacteria,2KX7Z@206389|Rhodocyclales	206389|Rhodocyclales	S	protein conserved in bacteria	-	-	-	ko:K09937	-	-	-	-	ko00000	-	-	-	DUF2065
k59_1526054_3	666681.M301_0946	3.6e-18	82.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,2VI9W@28216|Betaproteobacteria,2KM4X@206350|Nitrosomonadales	206350|Nitrosomonadales	O	HflC and HflK could regulate a protease	-	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
k59_879691_1	1537917.JU82_08420	1.37e-91	283.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2YMA3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_879743_1	1249480.B649_01445	1.15e-30	120.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2YMJS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,NIT,Response_reg
k59_409570_1	1249480.B649_07280	1.26e-51	177.0	COG2199@1|root,COG3706@2|Bacteria,1Q5A3@1224|Proteobacteria,430W0@68525|delta/epsilon subdivisions,2YRZB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_879779_1	387092.NIS_1077	2.73e-14	70.5	COG1734@1|root,COG1734@2|Bacteria,1NH80@1224|Proteobacteria,42WPX@68525|delta/epsilon subdivisions,2YQEX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG1734 DnaK suppressor protein	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
k59_879779_2	1249480.B649_05280	1.98e-29	108.0	2A97K@1|root,30YCA@2|Bacteria,1Q5FD@1224|Proteobacteria,42QSX@68525|delta/epsilon subdivisions,2YP0T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the UPF0763 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF2603
k59_349081_1	709032.Sulku_0982	2.39e-29	115.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2YMMT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_349081_2	1537917.JU82_01155	2.59e-75	229.0	COG3852@1|root,COG3852@2|Bacteria,1QAGK@1224|Proteobacteria,42RSW@68525|delta/epsilon subdivisions,2YPDC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_111625_1	929558.SMGD1_2864	1.28e-68	228.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42P4R@68525|delta/epsilon subdivisions,2YM92@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	DUF3365,MCPsignal
k59_1526187_1	1537917.JU82_02125	4.5e-227	633.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,42M5M@68525|delta/epsilon subdivisions,2YMGW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	iIT341.HP0144	COX1
k59_755218_1	1304883.KI912532_gene712	3.55e-96	289.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VHD3@28216|Betaproteobacteria,2KVRR@206389|Rhodocyclales	206389|Rhodocyclales	C	Acyl-CoA dehydrogenase, C-terminal domain	acd	-	1.3.8.4	ko:K00253	ko00280,ko01100,map00280,map01100	M00036	R04095	RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_409761_1	709032.Sulku_1263	1.57e-250	710.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42MX5@68525|delta/epsilon subdivisions,2YMSQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)	-	-	2.7.7.13,5.4.2.8	ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II
k59_755279_1	709032.Sulku_0280	9.17e-70	220.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,42M7V@68525|delta/epsilon subdivisions,2YMKI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
k59_1526248_1	749927.AMED_3565	0.000268	43.9	COG0300@1|root,COG0300@2|Bacteria,2IR2Z@201174|Actinobacteria	201174|Actinobacteria	S	KR domain	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
k59_1526248_2	1537917.JU82_09450	5.58e-135	388.0	COG2996@1|root,COG2996@2|Bacteria,1MXC3@1224|Proteobacteria,42P2A@68525|delta/epsilon subdivisions,2YMVD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	S1 domain	-	-	-	ko:K00243	-	-	-	-	ko00000	-	-	-	S1_2
k59_349223_1	1123399.AQVE01000019_gene1606	1.68e-63	211.0	COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,1RMB0@1236|Gammaproteobacteria,460QF@72273|Thiotrichales	72273|Thiotrichales	H	Mur ligase middle domain	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
k59_1818309_1	765912.Thimo_2579	2.75e-74	238.0	COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,1RMFT@1236|Gammaproteobacteria,1WX2I@135613|Chromatiales	135613|Chromatiales	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
k59_1818309_2	1198232.CYCME_1163	5.15e-09	58.2	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,1RNTY@1236|Gammaproteobacteria,45ZWD@72273|Thiotrichales	72273|Thiotrichales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k59_879970_1	1537917.JU82_08315	6.41e-144	414.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,42M5V@68525|delta/epsilon subdivisions,2YM81@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Cysteine desulfurase	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
k59_1818367_1	1123392.AQWL01000002_gene1933	3.8e-29	118.0	COG1273@1|root,COG1273@2|Bacteria,1QVC4@1224|Proteobacteria,2WGPK@28216|Betaproteobacteria,1KRUV@119069|Hydrogenophilales	119069|Hydrogenophilales	S	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3426,zinc_ribbon_5
k59_1818428_1	1249480.B649_02290	6.4e-105	311.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,42NBS@68525|delta/epsilon subdivisions,2YMPP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	riboflavin biosynthesis protein	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
k59_755476_1	1249480.B649_00265	5.78e-33	125.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,42M3S@68525|delta/epsilon subdivisions,2YN4P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	GTP-binding protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
k59_755476_2	709032.Sulku_0054	5.27e-51	176.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,42M3S@68525|delta/epsilon subdivisions,2YN4P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	GTP-binding protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
k59_755505_1	395494.Galf_1786	3.46e-87	269.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,2VHBW@28216|Betaproteobacteria,44V27@713636|Nitrosomonadales	28216|Betaproteobacteria	M	SMART PDZ DHR GLGF domain protein	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
k59_755505_2	1175306.GWL_16130	7.37e-25	103.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,2VHTX@28216|Betaproteobacteria,472UR@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_1818569_1	1172190.M947_00885	4.19e-38	133.0	2AJ5D@1|root,319PZ@2|Bacteria,1Q3HS@1224|Proteobacteria,42XCD@68525|delta/epsilon subdivisions,2YQQ3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Chemotaxis phosphatase CheX	-	-	-	-	-	-	-	-	-	-	-	-	CheX
k59_1077320_1	709032.Sulku_1062	6.39e-12	62.0	COG1959@1|root,COG1959@2|Bacteria,1N7JE@1224|Proteobacteria,42UAE@68525|delta/epsilon subdivisions,2YPWZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
k59_429972_1	1249480.B649_00210	3.33e-82	268.0	COG4581@1|root,COG4581@2|Bacteria,1MVD6@1224|Proteobacteria,42PR3@68525|delta/epsilon subdivisions,2YN2Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Mitochondrial degradasome RNA helicase subunit C terminal	-	-	3.6.4.13	ko:K17675	-	-	-	-	ko00000,ko01000,ko03029	-	-	-	Helicase_C,SUV3_C
k59_1307957_1	1366050.N234_25040	2.6e-94	292.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VJ5E@28216|Betaproteobacteria,1K0Z0@119060|Burkholderiaceae	28216|Betaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
k59_194310_1	485913.Krac_9178	1.84e-69	224.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_139928_1	1537917.JU82_02040	9.77e-43	155.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42M0A@68525|delta/epsilon subdivisions,2YNJ1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	cznA	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
k59_139928_2	1537917.JU82_02035	1.08e-36	126.0	2DHUN@1|root,30113@2|Bacteria,1Q6JK@1224|Proteobacteria,433A5@68525|delta/epsilon subdivisions,2YSRK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF3240)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3240
k59_1487878_1	709032.Sulku_0109	1.65e-33	115.0	COG0291@1|root,COG0291@2|Bacteria,1QDQ4@1224|Proteobacteria,42VSG@68525|delta/epsilon subdivisions,2YQAA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
k59_1780412_1	1249480.B649_06070	1.68e-110	337.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YNJ4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_1256506_1	1537917.JU82_09490	9.76e-64	197.0	COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,42SRC@68525|delta/epsilon subdivisions,2YP4I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
k59_75162_2	1124991.MU9_2412	5.53e-72	223.0	COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,1RPFE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	FeS assembly ATPase SufC	sufC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	iECH74115_1262.ECH74115_2396,iECIAI1_1343.ECIAI1_1734,iECIAI39_1322.ECIAI39_1376,iECSP_1301.ECSP_2249,iECs_1301.ECs2389,iEcSMS35_1347.EcSMS35_1514,iG2583_1286.G2583_2077,iSFV_1184.SFV_1705,iSFxv_1172.SFxv_1919,iSSON_1240.SSON_1474,iS_1188.S1844,iZ_1308.Z2710	ABC_tran
k59_1193124_1	1537917.JU82_07000	9.43e-64	210.0	COG1766@1|root,COG1766@2|Bacteria,1MUQR@1224|Proteobacteria,42N04@68525|delta/epsilon subdivisions,2YMF6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	The M ring may be actively involved in energy transduction	fliF	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
k59_1193124_2	1249480.B649_09160	1.78e-17	80.5	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,42NCH@68525|delta/epsilon subdivisions,2YMW7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_719401_1	709032.Sulku_1466	4.16e-107	341.0	COG2982@1|root,COG2982@2|Bacteria,1QA6E@1224|Proteobacteria,42NCN@68525|delta/epsilon subdivisions,2YM89@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_1,DUF3971
k59_139972_1	1249480.B649_00465	1.99e-105	322.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,42M20@68525|delta/epsilon subdivisions,2YMDG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
k59_1549634_1	338969.Rfer_3416	2.24e-63	202.0	COG0500@1|root,COG2226@2|Bacteria,1RB4F@1224|Proteobacteria,2VQPA@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
k59_1549634_2	159087.Daro_1487	1e-36	137.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,2VKXT@28216|Betaproteobacteria,2KU7Y@206389|Rhodocyclales	206389|Rhodocyclales	KT	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF_2,HTH_8,Sigma54_activat
k59_254617_1	709032.Sulku_2452	7.12e-94	289.0	COG2199@1|root,COG5000@1|root,COG2199@2|Bacteria,COG5000@2|Bacteria,1RGCV@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_4,PAS_9,Response_reg
k59_1022451_1	159087.Daro_1629	4.11e-140	413.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VIP3@28216|Betaproteobacteria,2KUJV@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k59_1431919_1	1537917.JU82_00595	1.66e-48	161.0	COG2107@1|root,COG2107@2|Bacteria,1NYEA@1224|Proteobacteria,42MXB@68525|delta/epsilon subdivisions,2YMNQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
k59_900379_1	159087.Daro_0020	1.53e-78	243.0	COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,2VIZJ@28216|Betaproteobacteria,2KUKQ@206389|Rhodocyclales	206389|Rhodocyclales	S	protein containing LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
k59_900379_2	1000565.METUNv1_03062	9.71e-36	125.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,2VQ4N@28216|Betaproteobacteria,2KW47@206389|Rhodocyclales	206389|Rhodocyclales	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
k59_1487951_1	159087.Daro_0302	5.18e-164	474.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,2VH5Q@28216|Betaproteobacteria,2KURC@206389|Rhodocyclales	206389|Rhodocyclales	H	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
k59_1549677_1	314285.KT71_05125	7.34e-05	44.7	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,1RN21@1236|Gammaproteobacteria,1JA4S@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle	rsmD	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052913,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
k59_1549677_2	765913.ThidrDRAFT_0118	2.42e-71	235.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,1RN3E@1236|Gammaproteobacteria,1WXE8@135613|Chromatiales	135613|Chromatiales	S	PFAM Peptidase M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_1193191_1	1165841.SULAR_05748	2.3e-14	71.6	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,42M3E@68525|delta/epsilon subdivisions,2YMQZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
k59_1193191_2	387093.SUN_1779	2.1e-67	210.0	COG0340@1|root,COG0340@2|Bacteria,1Q1NZ@1224|Proteobacteria,42RQM@68525|delta/epsilon subdivisions,2YP5C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	biotin acetyl-CoA-carboxylase ligase	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_LplA_LipB
k59_1138178_1	563040.Saut_0263	2.99e-109	320.0	COG0529@1|root,COG0529@2|Bacteria,1R6CM@1224|Proteobacteria,42PPR@68525|delta/epsilon subdivisions,2YTS4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Catalyzes the synthesis of activated sulfate	-	-	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,DUF2061
k59_1193192_1	1537917.JU82_10890	1.59e-111	330.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,42M9G@68525|delta/epsilon subdivisions,2YMSC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
k59_1022513_1	313612.L8106_01952	3.3e-20	94.7	COG4191@1|root,COG4191@2|Bacteria,1G3X5@1117|Cyanobacteria,1HH48@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal Transduction Histidine Kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3
k59_1259794_1	1537917.JU82_10725	7.38e-59	190.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Beta_helix,Big_2,Flagellin_C,Flagellin_N,VWA,VWA_2
k59_1259794_2	1249480.B649_02100	1.7e-30	110.0	29QY9@1|root,30BZ3@2|Bacteria,1QTGR@1224|Proteobacteria,42VBX@68525|delta/epsilon subdivisions,2YQ83@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_494402_1	1537917.JU82_03880	4.69e-46	151.0	2BSN9@1|root,32MQW@2|Bacteria,1Q3CP@1224|Proteobacteria,42X3U@68525|delta/epsilon subdivisions,2YQYI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	AF0941-like	-	-	-	-	-	-	-	-	-	-	-	-	AF0941-like
k59_1372311_1	1249480.B649_03115	8.69e-115	348.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42YH8@68525|delta/epsilon subdivisions,2YRAU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
k59_372166_2	309801.trd_A0412	1.37e-12	69.3	COG1067@1|root,COG1067@2|Bacteria,2G64R@200795|Chloroflexi,27XSI@189775|Thermomicrobia	189775|Thermomicrobia	O	Belongs to the peptidase S16 family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
k59_1079986_1	1453501.JELR01000002_gene565	0.000108	50.8	COG2199@1|root,COG3706@2|Bacteria,1MWHH@1224|Proteobacteria,1RRU7@1236|Gammaproteobacteria,465TD@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	7TMR-DISM extracellular 2	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,GGDEF
k59_1026026_2	76114.ebA1714	7.68e-31	114.0	2AP99@1|root,31EB9@2|Bacteria,1RM04@1224|Proteobacteria,2W2S7@28216|Betaproteobacteria,2KYW1@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1310187_2	1537917.JU82_04995	1.14e-74	224.0	2BS4Z@1|root,32M5X@2|Bacteria,1Q34G@1224|Proteobacteria,42WRS@68525|delta/epsilon subdivisions,2YQC8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_494441_1	266265.Bxe_A3502	2.18e-56	196.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,2VH64@28216|Betaproteobacteria,1K0NI@119060|Burkholderiaceae	28216|Betaproteobacteria	H	receptor	btuB	-	-	ko:K02014,ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.3	-	-	Plug,TonB_dep_Rec
k59_257065_1	1537917.JU82_09915	3.58e-77	237.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,42N10@68525|delta/epsilon subdivisions,2YMIF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	LU	DNA processing protein	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
k59_1666266_1	1304883.KI912532_gene2952	1.72e-103	303.0	COG2834@1|root,COG2834@2|Bacteria,1PXDV@1224|Proteobacteria,2VNNH@28216|Betaproteobacteria,2KWH0@206389|Rhodocyclales	206389|Rhodocyclales	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
k59_1195596_1	1242969.ATCC51562_421	4.01e-12	66.6	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,42MU5@68525|delta/epsilon subdivisions,2YM85@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_N
k59_1195596_2	1165841.SULAR_09479	3.04e-135	390.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,42RGS@68525|delta/epsilon subdivisions,2YNY5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_N
k59_1080027_1	525898.Sdel_1459	3.36e-52	188.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,43BRF@68525|delta/epsilon subdivisions,2YNRK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	TonB-dependent receptor plug	-	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
k59_555745_1	614083.AWQR01000054_gene1931	4.72e-49	177.0	COG0834@1|root,COG5001@1|root,COG0834@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,4A9PA@80864|Comamonadaceae	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,MASE1,NMT1,PAS,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3
k59_555745_2	159087.Daro_3559	1.29e-42	147.0	28X8G@1|root,2ZJ6K@2|Bacteria,1PAW1@1224|Proteobacteria,2W650@28216|Betaproteobacteria,2KZEZ@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_197314_1	537972.ABQU01000064_gene1490	2.94e-82	253.0	COG0673@1|root,COG0673@2|Bacteria,1MUP0@1224|Proteobacteria,42S6C@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	PFAM oxidoreductase domain protein	bplA	-	1.1.1.335	ko:K13020	ko00520,map00520	-	R10140	RC00182	ko00000,ko00001,ko01000,ko01005	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
k59_1259869_1	709032.Sulku_1304	2.64e-49	157.0	COG0633@1|root,COG0633@2|Bacteria,1NJF0@1224|Proteobacteria,42U1V@68525|delta/epsilon subdivisions,2YQ25@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Fer2
k59_1259869_2	990073.ATHU01000001_gene1798	1.52e-54	174.0	COG0633@1|root,COG0633@2|Bacteria,1PSR6@1224|Proteobacteria,42XGK@68525|delta/epsilon subdivisions,2YQWI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Fer2
k59_1259869_3	709032.Sulku_1302	4.4e-23	91.7	COG0760@1|root,COG0760@2|Bacteria,1QUCX@1224|Proteobacteria,42VM2@68525|delta/epsilon subdivisions,2YQCT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	NifZ domain	-	-	-	ko:K02597	-	-	-	-	ko00000	-	-	-	NifZ
k59_1782880_1	1249480.B649_11645	1.16e-27	110.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,42MEU@68525|delta/epsilon subdivisions,2YMUF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
k59_721158_1	1249480.B649_03140	4.94e-74	236.0	COG0739@1|root,COG0739@2|Bacteria,1N19D@1224|Proteobacteria,42SMK@68525|delta/epsilon subdivisions,2YTS0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_784951_1	159087.Daro_0953	1.38e-37	129.0	COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,2VQD9@28216|Betaproteobacteria,2KUI7@206389|Rhodocyclales	206389|Rhodocyclales	C	COG1905 NADH ubiquinone oxidoreductase 24 kD subunit	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
k59_784951_2	159087.Daro_0954	1.06e-70	224.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,2VJJ1@28216|Betaproteobacteria,2KUZS@206389|Rhodocyclales	206389|Rhodocyclales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
k59_1435331_1	1249480.B649_00955	8.32e-85	254.0	2AK36@1|root,31ASY@2|Bacteria,1Q62K@1224|Proteobacteria,42W11@68525|delta/epsilon subdivisions,2YQDG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF2393)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2393
k59_1310266_1	709032.Sulku_1385	9.51e-124	372.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,42M9Q@68525|delta/epsilon subdivisions,2YNFG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.20.2.1,1.20.9.1,1.7.7.2	ko:K00367,ko:K00372,ko:K08356	ko00910,ko01120,map00910,map01120	M00531	R00791,R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.6	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_963294_1	709032.Sulku_1960	1.01e-85	282.0	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG5000@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,COG5000@2|Bacteria,1RGKE@1224|Proteobacteria	1224|Proteobacteria	T	GAF domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,GAF,GAF_2,HATPase_c,HisKA,HisKA_2,HisKA_3,PAS,PAS_3,PAS_4,PAS_9,Pkinase,STAS,SpoIIE
k59_21069_2	90814.KL370891_gene1831	2.86e-38	140.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,1RN5Z@1236|Gammaproteobacteria,461G1@72273|Thiotrichales	72273|Thiotrichales	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k59_1026148_1	1197906.CAJQ02000052_gene4367	6.47e-23	95.1	COG2020@1|root,COG2020@2|Bacteria,1R7G6@1224|Proteobacteria,2VG1Y@28211|Alphaproteobacteria,3K6HR@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
k59_1026148_2	1443665.JACA01000047_gene5302	7.3e-21	93.2	COG0520@1|root,COG0520@2|Bacteria,4NDUB@976|Bacteroidetes,1HWSI@117743|Flavobacteriia,2YGVA@290174|Aquimarina	976|Bacteroidetes	E	Beta-eliminating lyase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
k59_1666330_1	159087.Daro_3926	8.13e-134	390.0	COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,2VHG1@28216|Betaproteobacteria,2KUK1@206389|Rhodocyclales	206389|Rhodocyclales	MU	COG1538 Outer membrane protein	tolC	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
k59_672826_1	1123393.KB891326_gene95	7.91e-124	363.0	COG1409@1|root,COG1409@2|Bacteria,1MV0H@1224|Proteobacteria,2WHIF@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
k59_1435364_2	1249480.B649_02730	1.69e-139	403.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,42NX0@68525|delta/epsilon subdivisions,2YMHX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Membrane protease subunits	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_1846612_1	159087.Daro_0339	2.31e-130	380.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,2VHQH@28216|Betaproteobacteria,2KVBF@206389|Rhodocyclales	206389|Rhodocyclales	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
k59_610975_1	709032.Sulku_2281	3.73e-132	380.0	COG0598@1|root,COG0598@2|Bacteria,1MWMP@1224|Proteobacteria,42KZB@68525|delta/epsilon subdivisions,2YN63@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
k59_142873_1	159087.Daro_0209	5.08e-94	295.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,2VHXF@28216|Betaproteobacteria,2KU7U@206389|Rhodocyclales	206389|Rhodocyclales	M	penicillin-binding protein 1A	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
k59_1724390_1	580332.Slit_2642	2.33e-73	222.0	2CDU4@1|root,348SV@2|Bacteria,1P0YW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_372315_2	1249480.B649_01230	2.08e-15	72.4	2AI7Y@1|root,318NF@2|Bacteria,1Q0NR@1224|Proteobacteria,42SAU@68525|delta/epsilon subdivisions,2YPMQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_845914_1	159087.Daro_3397	4.91e-44	144.0	COG3113@1|root,COG3113@2|Bacteria,1PJKD@1224|Proteobacteria,2VW6E@28216|Betaproteobacteria,2KXIR@206389|Rhodocyclales	206389|Rhodocyclales	S	STAS domain	-	-	-	ko:K07122	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	STAS_2
k59_845914_2	159087.Daro_3396	2.03e-51	168.0	COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,2VI81@28216|Betaproteobacteria,2KVD2@206389|Rhodocyclales	206389|Rhodocyclales	V	ABC-type multidrug transport system, ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_963411_1	387093.SUN_0520	2.82e-111	329.0	COG2046@1|root,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,42NAI@68525|delta/epsilon subdivisions,2YME3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	sulfate adenylyltransferase	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
k59_902689_1	1502770.JQMG01000001_gene2274	1.75e-52	172.0	COG0778@1|root,COG0778@2|Bacteria,1Q0KA@1224|Proteobacteria,2W5F5@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_963420_1	1144319.PMI16_01868	5.04e-05	47.4	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,2VMJI@28216|Betaproteobacteria,475DW@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PAAR_motif,Peptidase_C39,RHS,RHS_repeat
k59_1724428_1	387093.SUN_0361	4.56e-28	111.0	COG1579@1|root,COG1579@2|Bacteria,1R7GT@1224|Proteobacteria,42P3S@68525|delta/epsilon subdivisions,2YMAN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COG1579 Zn-ribbon protein possibly nucleic acid-binding	-	-	3.5.4.16	ko:K07164,ko:K22391	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	zf-RING_7
k59_432355_1	1249480.B649_01010	1.38e-48	160.0	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,42M3Y@68525|delta/epsilon subdivisions,2YMD5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
k59_432355_2	1249480.B649_01005	3.23e-15	75.9	2C99Z@1|root,2Z9YV@2|Bacteria,1N0B7@1224|Proteobacteria,42P3M@68525|delta/epsilon subdivisions,2YMWY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF3373)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3373
k59_1260036_2	1249480.B649_00335	1.47e-46	165.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42Q5F@68525|delta/epsilon subdivisions,2YPMR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	Cache_3-Cache_2,MCPsignal
k59_432362_1	929558.SMGD1_0288	6.16e-54	191.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YMMN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1553152_1	717773.Thicy_0820	5.55e-65	221.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,1RN03@1236|Gammaproteobacteria,45ZYT@72273|Thiotrichales	72273|Thiotrichales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_1310390_1	1236959.BAMT01000006_gene380	9.25e-50	172.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,2VHAY@28216|Betaproteobacteria,2KKM5@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_19
k59_672948_1	1249480.B649_10700	4.74e-175	526.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,43DMZ@68525|delta/epsilon subdivisions,2YMMS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_432365_1	395494.Galf_1136	1.08e-103	323.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,2VJ5Q@28216|Betaproteobacteria,44VGS@713636|Nitrosomonadales	28216|Betaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_167153_1	204773.HEAR0273	0.000471	42.4	COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,2VHAX@28216|Betaproteobacteria,4725E@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	Rhodanese Homology Domain	sseA	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
k59_167153_2	1304883.KI912532_gene3061	2.46e-70	213.0	2CU7M@1|root,32SUS@2|Bacteria,1N1WF@1224|Proteobacteria,2VUS0@28216|Betaproteobacteria,2KWRI@206389|Rhodocyclales	206389|Rhodocyclales	S	SpoIIAA-like	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIAA-like
k59_167153_3	159087.Daro_3057	1.21e-11	63.5	COG0697@1|root,COG0697@2|Bacteria,1MZXM@1224|Proteobacteria,2VK90@28216|Betaproteobacteria,2KW2D@206389|Rhodocyclales	206389|Rhodocyclales	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_1581284_1	709032.Sulku_0710	5.16e-73	253.0	COG0515@1|root,COG2199@1|root,COG2200@1|root,COG2203@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2199@2|Bacteria,COG2200@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,1QYCX@1224|Proteobacteria,43CBC@68525|delta/epsilon subdivisions,2YR81@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_1167740_1	159087.Daro_3048	2.19e-101	302.0	COG2199@1|root,COG3706@2|Bacteria,1R6GI@1224|Proteobacteria,2VM5N@28216|Betaproteobacteria,2KWR2@206389|Rhodocyclales	206389|Rhodocyclales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_394685_1	1121004.ATVC01000070_gene1648	2.97e-53	178.0	COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,2VH4W@28216|Betaproteobacteria,2KQ6V@206351|Neisseriales	206351|Neisseriales	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroG	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
k59_519334_1	709032.Sulku_1385	3.06e-109	333.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,42M9Q@68525|delta/epsilon subdivisions,2YNFG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.20.2.1,1.20.9.1,1.7.7.2	ko:K00367,ko:K00372,ko:K08356	ko00910,ko01120,map00910,map01120	M00531	R00791,R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.6	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_1513881_1	709032.Sulku_1510	2.66e-131	383.0	COG0535@1|root,COG1433@1|root,COG0535@2|Bacteria,COG1433@2|Bacteria,1MWDC@1224|Proteobacteria,42MHB@68525|delta/epsilon subdivisions,2YNUZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Nitrogenase cofactor biosynthesis protein NifB	-	-	-	ko:K02585	-	-	-	-	ko00000	-	-	-	Nitro_FeMo-Co,Radical_SAM
k59_741474_1	177437.HRM2_39790	1.85e-05	52.8	COG2227@1|root,COG2227@2|Bacteria,1QWNW@1224|Proteobacteria,42SSA@68525|delta/epsilon subdivisions,2X74S@28221|Deltaproteobacteria,2MMCM@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
k59_223683_1	563040.Saut_0053	4.7e-20	90.1	COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,42MPV@68525|delta/epsilon subdivisions,2YNN7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
k59_223683_2	563040.Saut_0052	6.3e-69	223.0	COG0569@1|root,COG0569@2|Bacteria,1MW8R@1224|Proteobacteria,42NWZ@68525|delta/epsilon subdivisions,2YNAD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	K transport system, NAD-binding component	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
k59_1581323_1	929558.SMGD1_2155	9.58e-08	56.6	COG3290@1|root,COG4191@1|root,COG3290@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2YTKC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
k59_812892_1	1304883.KI912532_gene2060	6.01e-107	317.0	COG1485@1|root,COG1485@2|Bacteria,1MUUW@1224|Proteobacteria,2VHQX@28216|Betaproteobacteria,2KUMJ@206389|Rhodocyclales	206389|Rhodocyclales	S	AFG1-like ATPase	afg	-	-	ko:K06916	-	-	-	-	ko00000,ko03036	-	-	-	AFG1_ATPase
k59_812892_2	159087.Daro_2854	5.24e-27	105.0	COG4796@1|root,COG4796@2|Bacteria,1RCNA@1224|Proteobacteria,2WGZA@28216|Betaproteobacteria,2KWAH@206389|Rhodocyclales	206389|Rhodocyclales	U	Bacterial type II and III secretion system protein	-	-	-	-	-	-	-	-	-	-	-	-	Secretin
k59_394777_1	926692.AZYG01000011_gene1124	2.62e-44	163.0	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,2490U@186801|Clostridia	186801|Clostridia	Q	Belongs to the ATP-dependent AMP-binding enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,NAD_binding_4,PP-binding
k59_1581376_1	314256.OG2516_06444	1.08e-16	81.6	COG0477@1|root,COG2814@2|Bacteria,1R7DW@1224|Proteobacteria,2U0NT@28211|Alphaproteobacteria,2PFI6@252301|Oceanicola	28211|Alphaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
k59_1581376_2	1165841.SULAR_06663	1.05e-109	329.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42NVA@68525|delta/epsilon subdivisions,2YMYW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
k59_1054626_1	1249480.B649_09495	2.46e-112	338.0	COG0223@1|root,COG1024@1|root,COG0223@2|Bacteria,COG1024@2|Bacteria,1MWYJ@1224|Proteobacteria,42PAJ@68525|delta/epsilon subdivisions,2YNKB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	IJ	Enoyl-CoA hydratase/isomerase	-	-	-	ko:K19640	-	-	-	-	ko00000,ko02022	-	-	-	ECH_1,Formyl_trans_C,Formyl_trans_N
k59_280560_2	1121035.AUCH01000002_gene1460	8.48e-74	228.0	COG2265@1|root,COG2265@2|Bacteria,1QV4X@1224|Proteobacteria,2WGYG@28216|Betaproteobacteria,2KX4K@206389|Rhodocyclales	206389|Rhodocyclales	J	Thiopurine S-methyltransferase (TPMT)	-	-	2.1.1.67	ko:K00569	ko00983,map00983	-	R08236,R08239,R08246	RC00003,RC00980,RC02277	ko00000,ko00001,ko01000	-	-	-	TPMT
k59_223740_1	41431.PCC8801_2391	1.22e-29	117.0	COG1874@1|root,COG1874@2|Bacteria,1G9Y8@1117|Cyanobacteria,3KIZ8@43988|Cyanothece	1117|Cyanobacteria	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_223740_2	1492922.GY26_05970	4.29e-32	124.0	COG3754@1|root,COG5610@1|root,COG3754@2|Bacteria,COG5610@2|Bacteria,1Q4T5@1224|Proteobacteria,1RZ2P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Lipopolysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	RgpF
k59_866510_1	159087.Daro_4059	1.42e-47	164.0	COG4402@1|root,COG4402@2|Bacteria,1MVMM@1224|Proteobacteria,2VZKJ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2330
k59_866510_2	640081.Dsui_3439	8.89e-40	147.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VQDF@28216|Betaproteobacteria,2KY4C@206389|Rhodocyclales	206389|Rhodocyclales	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
k59_1872659_2	159087.Daro_0189	2.5e-49	164.0	COG1560@1|root,COG1560@2|Bacteria,1Q41N@1224|Proteobacteria,2VKN0@28216|Betaproteobacteria,2KUY8@206389|Rhodocyclales	206389|Rhodocyclales	M	acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
k59_280589_1	1111728.ATYS01000015_gene4740	1.69e-44	161.0	COG0318@1|root,COG0318@2|Bacteria,1PH7B@1224|Proteobacteria,1S1KM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
k59_334138_1	1537917.JU82_05785	6.23e-65	211.0	COG3203@1|root,COG3203@2|Bacteria,1QVBP@1224|Proteobacteria,42M72@68525|delta/epsilon subdivisions,2YNNX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	outer membrane porin, OprD family	-	-	-	-	-	-	-	-	-	-	-	-	OprD
k59_1286557_1	76114.ebA6397	5.63e-24	98.2	COG1076@1|root,COG1076@2|Bacteria,1RHZX@1224|Proteobacteria,2VSD5@28216|Betaproteobacteria,2KWCY@206389|Rhodocyclales	206389|Rhodocyclales	O	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA	hscB	-	-	ko:K04082	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	HSCB_C
k59_1872690_1	700508.D174_04570	9.02e-25	101.0	COG0191@1|root,COG0191@2|Bacteria,2GM5P@201174|Actinobacteria,233VE@1762|Mycobacteriaceae	201174|Actinobacteria	G	fructose-bisphosphate aldolase	fba	GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016830,GO:0016832,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
k59_1872690_2	648996.Theam_0179	2.53e-27	110.0	COG0104@1|root,COG0104@2|Bacteria,2G3TB@200783|Aquificae	200783|Aquificae	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
k59_519443_2	1485544.JQKP01000002_gene1384	4.22e-19	85.5	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,2VIEJ@28216|Betaproteobacteria,44V7X@713636|Nitrosomonadales	28216|Betaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
k59_992676_1	709032.Sulku_2242	5.61e-35	132.0	COG0457@1|root,COG0457@2|Bacteria,1Q60C@1224|Proteobacteria,42X29@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Anaphase-promoting complex, cyclosome, subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC3
k59_1806089_1	1249480.B649_05335	2.34e-11	63.9	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42MS0@68525|delta/epsilon subdivisions,2YMTX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_1806089_2	1249480.B649_05340	1.52e-59	189.0	2AJ5J@1|root,319Q6@2|Bacteria,1Q3I6@1224|Proteobacteria,42XD0@68525|delta/epsilon subdivisions,2YR0I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1167954_1	1502770.JQMG01000001_gene665	1.67e-176	493.0	COG4422@1|root,COG4422@2|Bacteria,1MXQI@1224|Proteobacteria,2VJP8@28216|Betaproteobacteria,2KNPA@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Protein of unknown function (DUF5131)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5131
k59_1750864_1	395494.Galf_0343	1.11e-49	162.0	COG4701@1|root,COG4701@2|Bacteria,1N8HR@1224|Proteobacteria,2VW5Y@28216|Betaproteobacteria,44W40@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
k59_1466328_1	1304883.KI912532_gene146	1.74e-80	246.0	COG1684@1|root,COG1684@2|Bacteria,1NIF4@1224|Proteobacteria,2VQ64@28216|Betaproteobacteria,2KW6G@206389|Rhodocyclales	206389|Rhodocyclales	N	Role in flagellar biosynthesis	fliR	-	-	ko:K02421	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1
k59_1693476_1	395494.Galf_2085	8.97e-16	75.9	COG0557@1|root,COG0557@2|Bacteria,1NGSQ@1224|Proteobacteria,2VHMM@28216|Betaproteobacteria,44VP2@713636|Nitrosomonadales	28216|Betaproteobacteria	K	RNB	rnb	-	3.1.13.1	ko:K01147	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNB
k59_1693476_2	267608.RSc3260	1.3e-17	79.7	COG4654@1|root,COG4654@2|Bacteria,1N6UN@1224|Proteobacteria,2VW1Y@28216|Betaproteobacteria,1K982@119060|Burkholderiaceae	28216|Betaproteobacteria	C	cytochrome C	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,Cytochrome_CBB3
k59_1400528_1	292.DM42_6002	4.13e-36	133.0	COG1028@1|root,COG1028@2|Bacteria,1MWCY@1224|Proteobacteria,2VRP6@28216|Betaproteobacteria,1K616@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_460249_1	929558.SMGD1_1574	5.32e-53	187.0	COG0715@1|root,COG0834@1|root,COG2199@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42MCD@68525|delta/epsilon subdivisions,2YN6K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	ET	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,NMT1,SBP_bac_3
k59_1754323_1	1537917.JU82_02940	5.81e-51	163.0	2B1KW@1|root,31U2C@2|Bacteria,1QRVW@1224|Proteobacteria,42WG1@68525|delta/epsilon subdivisions,2YQCP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1518112_1	62928.azo2780	2.9e-91	292.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,2VH6Z@28216|Betaproteobacteria,2KVJ1@206389|Rhodocyclales	206389|Rhodocyclales	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_1518112_2	640081.Dsui_3349	1.75e-20	84.7	2EDQM@1|root,337K9@2|Bacteria,1NCVD@1224|Proteobacteria,2VWUM@28216|Betaproteobacteria,2KXG9@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_996650_1	929558.SMGD1_1210	1.56e-27	111.0	COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,42NZ4@68525|delta/epsilon subdivisions,2YNNY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	COG2067 Long-chain fatty acid transport protein	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k59_1637032_1	709032.Sulku_0836	3.78e-93	301.0	COG2202@1|root,COG2203@1|root,COG3452@1|root,COG5001@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3452@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YMHP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GGDEF,PAS_4,PAS_9
k59_1518118_1	709032.Sulku_1903	7.38e-42	140.0	COG3787@1|root,COG3787@2|Bacteria,1RH76@1224|Proteobacteria,42TS4@68525|delta/epsilon subdivisions,2YPWQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	cofactor binding	Cj1449c	-	-	ko:K09979	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
k59_171832_1	1249480.B649_07410	4.84e-36	134.0	COG1538@1|root,COG1538@2|Bacteria,1MYX2@1224|Proteobacteria,42MHZ@68525|delta/epsilon subdivisions,2YNGC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	Outer membrane efflux protein	-	-	-	ko:K12543	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	1.B.17,3.A.1.109.4	-	-	OEP,OmpA,TSP_3
k59_817285_1	90813.JQMT01000001_gene1298	7.84e-37	132.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,1RN3A@1236|Gammaproteobacteria,45ZSI@72273|Thiotrichales	72273|Thiotrichales	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
k59_817285_2	998674.ATTE01000001_gene2139	3.01e-22	93.6	COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,1RN0C@1236|Gammaproteobacteria,460MV@72273|Thiotrichales	72273|Thiotrichales	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
k59_1693518_2	866889.E1XUA1_9CAUD	1.34e-27	108.0	4QG66@10239|Viruses,4QUJP@28883|Caudovirales	28883|Caudovirales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1693518_3	136084.Q9G0H0_9CAUD	1.82e-24	106.0	4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses  no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae	10744|Podoviridae	S	DNA polymerase family A	-	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360	-	-	-	-	-	-	-	-	-	-	-
k59_338141_1	1123399.AQVE01000010_gene3303	5.65e-15	75.9	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,1RM7U@1236|Gammaproteobacteria,460DK@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
k59_996698_1	472759.Nhal_3799	6.84e-66	208.0	COG0730@1|root,COG0730@2|Bacteria,1R712@1224|Proteobacteria,1S6UI@1236|Gammaproteobacteria,1WXAK@135613|Chromatiales	135613|Chromatiales	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k59_996698_2	156889.Mmc1_1547	4.46e-31	117.0	COG2062@1|root,COG2062@2|Bacteria,1N0FX@1224|Proteobacteria,2UBYD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	phosphohistidine phosphatase, SixA	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
k59_338188_1	1132855.KB913035_gene1686	1.4e-56	182.0	COG0730@1|root,COG0730@2|Bacteria,1MWX2@1224|Proteobacteria,2VMUD@28216|Betaproteobacteria,2KKHR@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k59_338188_2	233412.HD_1030	1.74e-16	77.8	COG0583@1|root,COG0583@2|Bacteria,1MU8N@1224|Proteobacteria,1RN7T@1236|Gammaproteobacteria,1Y73E@135625|Pasteurellales	135625|Pasteurellales	K	Transcriptional regulator	cysB	-	-	ko:K13634	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k59_338194_1	1485544.JQKP01000001_gene953	3.42e-71	231.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,44W5G@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
k59_870115_1	673860.AciM339_1206	2.26e-77	245.0	COG1503@1|root,arCOG01742@2157|Archaea,2XSV5@28890|Euryarchaeota,3F2IF@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA	prf1	-	-	ko:K03265	ko03015,map03015	-	-	-	ko00000,ko00001,ko03012,ko03019	-	-	-	eRF1_1,eRF1_2,eRF1_3
k59_641847_1	1177179.A11A3_02757	4.51e-25	106.0	COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,1RP2Y@1236|Gammaproteobacteria,1XID6@135619|Oceanospirillales	135619|Oceanospirillales	T	Phosphate starvation-inducible protein PhoH	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
k59_1108494_1	1123514.KB905899_gene1539	3.61e-89	275.0	COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,1RMJA@1236|Gammaproteobacteria,4602E@72273|Thiotrichales	72273|Thiotrichales	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
k59_996781_1	666681.M301_0155	7.05e-57	189.0	COG0415@1|root,COG0415@2|Bacteria,1MUKB@1224|Proteobacteria,2VND9@28216|Betaproteobacteria,2KM0Y@206350|Nitrosomonadales	206350|Nitrosomonadales	L	FAD binding domain of DNA photolyase	-	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	FAD_binding_7
k59_996781_2	1502770.JQMG01000001_gene1029	2.39e-109	317.0	COG1704@1|root,COG1704@2|Bacteria,1R9YG@1224|Proteobacteria,2VQ2A@28216|Betaproteobacteria,2KNHA@206350|Nitrosomonadales	206350|Nitrosomonadales	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
k59_338246_1	1249480.B649_03015	3.61e-125	366.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,42NDT@68525|delta/epsilon subdivisions,2YMIS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
k59_1108503_1	1249480.B649_01375	5.08e-114	331.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,42M61@68525|delta/epsilon subdivisions,2YM9D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the KdsA family	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
k59_641871_1	1249480.B649_06750	1.98e-24	94.7	COG1433@1|root,COG1433@2|Bacteria,1N05Z@1224|Proteobacteria,42VFK@68525|delta/epsilon subdivisions,2YQG3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Dinitrogenase iron-molybdenum cofactor biosynthesis protein	-	-	-	ko:K02596	-	-	-	-	ko00000	-	-	-	Nitro_FeMo-Co
k59_641871_2	1537917.JU82_10460	5.76e-84	248.0	COG1145@1|root,COG1145@2|Bacteria,1QZ2K@1224|Proteobacteria,42SFI@68525|delta/epsilon subdivisions,2YPQC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_7
k59_641871_3	1537917.JU82_10465	1.03e-34	122.0	COG3585@1|root,COG3585@2|Bacteria	2|Bacteria	H	molybdate ion transport	-	-	3.6.3.29,3.6.3.55	ko:K02017,ko:K06857	ko02010,map02010	M00186,M00189	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.2,3.A.1.6.4,3.A.1.8	-	-	ABC_tran,TOBE
k59_102969_1	1453503.AU05_12925	5.22e-61	196.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,1RM8I@1236|Gammaproteobacteria,1YDFW@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iJN746.PP_4715	TIM
k59_102969_2	159087.Daro_0948	6.34e-58	182.0	COG1314@1|root,COG1314@2|Bacteria,1N8MF@1224|Proteobacteria,2VU0P@28216|Betaproteobacteria,2KWZZ@206389|Rhodocyclales	206389|Rhodocyclales	U	preprotein translocase	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
k59_1754468_1	118005.AWNK01000015_gene1027	2e-41	157.0	COG2208@1|root,COG3850@1|root,COG2208@2|Bacteria,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	srrB	-	-	ko:K20971	ko02025,map02025	-	-	-	ko00000,ko00001,ko01001,ko02022	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,GAF_2,HAMP,PAS_9,Reg_prop,SpoIIE,TPR_12,TPR_8,Y_Y_Y
k59_934666_2	1249480.B649_08310	6.01e-36	126.0	COG0711@1|root,COG0711@2|Bacteria,1Q9TP@1224|Proteobacteria,42U87@68525|delta/epsilon subdivisions,2YPT1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
k59_1877170_1	1163617.SCD_n01413	5.58e-34	134.0	COG3829@1|root,COG5001@1|root,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,PAS_3,PAS_9,Response_reg
k59_934671_1	709032.Sulku_1911	1.63e-74	242.0	COG5000@1|root,COG5000@2|Bacteria,1NU7E@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,PAS,PAS_10,PAS_9
k59_285563_2	189753.AXAS01000073_gene7661	5.44e-66	225.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,3JV04@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	V	Efflux pump membrane transporter	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_1400725_2	1123487.KB892866_gene1692	5.52e-17	75.9	COG0236@1|root,COG0236@2|Bacteria,1NEMA@1224|Proteobacteria,2VW0X@28216|Betaproteobacteria,2KXFD@206389|Rhodocyclales	206389|Rhodocyclales	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
k59_1400725_3	755732.Fluta_1451	3.05e-16	82.0	COG0842@1|root,COG0842@2|Bacteria,4NGFA@976|Bacteroidetes,1HYPT@117743|Flavobacteriia,2PAFC@246874|Cryomorphaceae	976|Bacteroidetes	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
k59_1108559_1	326298.Suden_0799	4.12e-70	236.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YMMN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1108559_2	709032.Sulku_0867	1.82e-45	150.0	2BT5R@1|root,32NAM@2|Bacteria,1Q3P8@1224|Proteobacteria,42XKB@68525|delta/epsilon subdivisions,2YQR6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_996848_1	665952.HMPREF1015_00723	1.75e-06	51.2	COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,4HGXT@91061|Bacilli,1ZFNI@1386|Bacillus	91061|Bacilli	L	Methyltransferase	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
k59_996848_2	379731.PST_4002	3.68e-59	189.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,1S41J@1236|Gammaproteobacteria,1YZWH@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	GO:0003674,GO:0003824,GO:0004595,GO:0005488,GO:0005515,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iPC815.YPO0053,iSDY_1059.SDY_4064	CTP_transf_like
k59_1877188_1	1121374.KB891575_gene1106	1.37e-06	55.5	COG2304@1|root,COG2304@2|Bacteria,1RIXD@1224|Proteobacteria,1S6EY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
k59_399989_1	709032.Sulku_1396	2.35e-108	337.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,42M4I@68525|delta/epsilon subdivisions,2YMFT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_338324_2	1163407.UU7_11482	1.38e-15	76.6	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,1S8RS@1236|Gammaproteobacteria,1X7NG@135614|Xanthomonadales	135614|Xanthomonadales	U	Biopolymer transport protein	tolR	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
k59_1108571_1	159087.Daro_3557	1.95e-51	167.0	COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,2VIM1@28216|Betaproteobacteria,2KUZU@206389|Rhodocyclales	206389|Rhodocyclales	K	Transcriptional regulatory protein, C terminal	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_1108571_2	159087.Daro_3556	5.07e-53	182.0	COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,2VH9I@28216|Betaproteobacteria,2KUQJ@206389|Rhodocyclales	206389|Rhodocyclales	P	Transport of potassium into the cell	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
k59_1108579_1	75379.Tint_3048	5.31e-33	132.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,1KJ1H@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_46808_1	709032.Sulku_2200	9.35e-174	505.0	COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,42M8J@68525|delta/epsilon subdivisions,2YNGB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member	recD	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2,Viral_helicase1
k59_745739_1	1537917.JU82_00585	4.52e-117	340.0	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,42P86@68525|delta/epsilon subdivisions,2YN53@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	iIT341.HP1418	MurB_C
k59_1246162_1	1249480.B649_06595	2.19e-205	576.0	COG0535@1|root,COG1433@1|root,COG0535@2|Bacteria,COG1433@2|Bacteria,1MWDC@1224|Proteobacteria,42MHB@68525|delta/epsilon subdivisions,2YNUZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Nitrogenase cofactor biosynthesis protein NifB	-	-	-	ko:K02585	-	-	-	-	ko00000	-	-	-	Nitro_FeMo-Co,Radical_SAM
k59_362544_1	879212.DespoDRAFT_00221	2.22e-110	337.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MHP@68525|delta/epsilon subdivisions,2WIQG@28221|Deltaproteobacteria,2MJ8G@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
k59_1010993_2	709032.Sulku_1654	1.31e-35	129.0	COG1076@1|root,COG1076@2|Bacteria,1N8QM@1224|Proteobacteria,43B25@68525|delta/epsilon subdivisions,2YT59@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	DnaJ domain protein	-	-	-	ko:K05801	-	-	-	-	ko00000,ko03110	-	-	-	DnaJ,TerB
k59_1360739_1	1249480.B649_05265	3.64e-137	394.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,42N7U@68525|delta/epsilon subdivisions,2YN72@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	PFAM Radical SAM domain protein	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Radical_SAM
k59_773239_1	1165841.SULAR_07595	1.41e-58	190.0	COG0492@1|root,COG0492@2|Bacteria,1NDW6@1224|Proteobacteria,42MUD@68525|delta/epsilon subdivisions,2YMV2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	pyridine nucleotide-disulfide oxidoreductase	trxB_2	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	FixS,Pyr_redox_3
k59_362582_1	666681.M301_1309	7.98e-75	247.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,2VI2G@28216|Betaproteobacteria,2KM41@206350|Nitrosomonadales	206350|Nitrosomonadales	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	GlnD_UR_UTase,HD,NTP_transf_2
k59_1421476_2	709032.Sulku_1005	1.23e-27	107.0	COG0694@1|root,COG0822@1|root,COG0694@2|Bacteria,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,42MT6@68525|delta/epsilon subdivisions,2YMXY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CO	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins	-	-	-	ko:K13819	-	-	-	-	ko00000	-	-	-	Fer2_BFD,NifU,NifU_N
k59_659160_1	1165841.SULAR_05098	1.5e-14	71.6	COG0731@1|root,COG0731@2|Bacteria,1QG36@1224|Proteobacteria,42M82@68525|delta/epsilon subdivisions,2YN42@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
k59_659160_2	1165841.SULAR_05103	7.21e-134	395.0	COG0232@1|root,COG0232@2|Bacteria	2|Bacteria	F	Belongs to the dGTPase family. Type 2 subfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1360799_1	709032.Sulku_1027	2.52e-24	99.4	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,42P35@68525|delta/epsilon subdivisions,2YN2K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	iIT341.HP0867	LpxB
k59_1360799_2	1249480.B649_04275	2.99e-45	149.0	COG2863@1|root,COG2863@2|Bacteria,1PFA2@1224|Proteobacteria,42XJ8@68525|delta/epsilon subdivisions,2YQVM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	cytochrome c class I	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
k59_659161_1	292415.Tbd_1627	7.91e-38	143.0	COG1344@1|root,COG1344@2|Bacteria,1PJUJ@1224|Proteobacteria,2VM4I@28216|Betaproteobacteria,1KRMX@119069|Hydrogenophilales	119069|Hydrogenophilales	N	Bacterial flagellin N-terminal helical region	-	-	-	ko:K02397	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
k59_773294_2	159087.Daro_1811	1.12e-54	176.0	COG2258@1|root,COG2258@2|Bacteria,1RH4S@1224|Proteobacteria,2VRI3@28216|Betaproteobacteria,2KXIU@206389|Rhodocyclales	206389|Rhodocyclales	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
k59_421926_1	717773.Thicy_0255	1e-47	167.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,1RMJE@1236|Gammaproteobacteria,46079@72273|Thiotrichales	72273|Thiotrichales	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
k59_1068428_1	387093.SUN_1066	1.04e-103	328.0	COG0642@1|root,COG3850@1|root,COG2205@2|Bacteria,COG3850@2|Bacteria,1NRP8@1224|Proteobacteria,42Z1P@68525|delta/epsilon subdivisions,2YRFA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	HAMP domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k59_659182_1	1249480.B649_04225	6.89e-118	345.0	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,42PA2@68525|delta/epsilon subdivisions,2YN18@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
k59_1596375_2	387093.SUN_1516	4.8e-27	110.0	COG0438@1|root,COG0438@2|Bacteria,1N0DG@1224|Proteobacteria,42MJF@68525|delta/epsilon subdivisions,2YMG5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	hmm pf00534	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glycos_transf_1
k59_421934_1	1537917.JU82_02250	1.42e-144	417.0	2AIAA@1|root,318R4@2|Bacteria,1Q0T4@1224|Proteobacteria,42SFV@68525|delta/epsilon subdivisions,2YPR6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	1.13.11.63	ko:K21817	-	-	-	-	ko00000,ko01000	-	-	-	-
k59_1301920_2	709032.Sulku_2479	1.51e-66	206.0	2C5EJ@1|root,33CUW@2|Bacteria,1PVYS@1224|Proteobacteria,4327Q@68525|delta/epsilon subdivisions,2YSV7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function VcgC/VcgE (DUF2780)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2780
k59_773328_1	477184.KYC_19364	5.68e-55	194.0	COG3299@1|root,COG3299@2|Bacteria,1P3E0@1224|Proteobacteria,2VKDQ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J,PA14
k59_421946_1	709032.Sulku_1996	1.36e-155	438.0	COG0745@1|root,COG0745@2|Bacteria,1PGAE@1224|Proteobacteria,4348Y@68525|delta/epsilon subdivisions,2YREY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_421946_2	1537917.JU82_03400	7.46e-29	115.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42Z31@68525|delta/epsilon subdivisions,2YRAR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Hpt sensor hybrid histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
k59_1479599_1	1537917.JU82_09190	1.6e-114	339.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,42MJT@68525|delta/epsilon subdivisions,2YMEB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
k59_1596404_1	1537917.JU82_02515	7.69e-102	303.0	COG2957@1|root,COG2957@2|Bacteria,1MX65@1224|Proteobacteria,42NAS@68525|delta/epsilon subdivisions,2YN3V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the agmatine deiminase family	aguA	-	-	-	-	-	-	-	-	-	-	-	PAD_porph
k59_1185392_1	709032.Sulku_2256	2.05e-30	112.0	COG0179@1|root,COG0179@2|Bacteria,1MVFA@1224|Proteobacteria,42S7E@68525|delta/epsilon subdivisions,2YP7T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	2-keto-4-pentenoate hydratase	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
k59_1185392_2	709032.Sulku_2257	1.06e-64	207.0	COG0642@1|root,COG2205@2|Bacteria,1Q179@1224|Proteobacteria,4313A@68525|delta/epsilon subdivisions,2YS9S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07645	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	-
k59_659241_2	338969.Rfer_0420	1.15e-16	75.1	2DVDD@1|root,32UZ7@2|Bacteria,1NGRW@1224|Proteobacteria,2VY85@28216|Betaproteobacteria,4AEXN@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF2933)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2933
k59_659241_3	159087.Daro_2277	1.9e-79	239.0	COG2020@1|root,COG2020@2|Bacteria,1MUBZ@1224|Proteobacteria,2VJJ4@28216|Betaproteobacteria,2KVCR@206389|Rhodocyclales	206389|Rhodocyclales	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
k59_12174_1	156889.Mmc1_3249	1.27e-165	505.0	COG0841@1|root,COG3087@1|root,COG0841@2|Bacteria,COG3087@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1655227_1	1408164.MOLA814_00220	9.27e-20	87.4	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,2VH3P@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
k59_1655227_2	85643.Tmz1t_1262	1.61e-45	147.0	COG4327@1|root,COG4327@2|Bacteria,1N0TK@1224|Proteobacteria,2VUFA@28216|Betaproteobacteria,2KX0Q@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of unknown function (DUF4212)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4212
k59_12178_1	1537917.JU82_00090	4.1e-73	234.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,42M2G@68525|delta/epsilon subdivisions,2YMS0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
k59_952006_1	709032.Sulku_1832	3.55e-102	311.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,42MJE@68525|delta/epsilon subdivisions,2YN7F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	actP	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
k59_130165_1	653733.Selin_0951	2.1e-104	318.0	COG0702@1|root,COG0702@2|Bacteria	2|Bacteria	GM	epimerase	ybjT	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10,TspO_MBR
k59_130167_1	709032.Sulku_1755	3.88e-32	120.0	COG1305@1|root,COG1305@2|Bacteria,1MVMI@1224|Proteobacteria,42PJK@68525|delta/epsilon subdivisions,2YNSY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Bacterial transglutaminase-like N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
k59_130167_2	709032.Sulku_1756	2.26e-24	102.0	COG2307@1|root,COG2308@1|root,COG2307@2|Bacteria,COG2308@2|Bacteria,1MX5P@1224|Proteobacteria,42NB9@68525|delta/epsilon subdivisions,2YNN4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E,CP_ATPgrasp_2
k59_422004_1	999541.bgla_1g30410	1.43e-58	198.0	COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,2VHBQ@28216|Betaproteobacteria,1K0F8@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_952012_1	387093.SUN_1865	2.75e-38	140.0	arCOG03638@1|root,2Z8W3@2|Bacteria,1N2PH@1224|Proteobacteria,42P6Y@68525|delta/epsilon subdivisions,2YMZI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF1538)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1538
k59_952012_2	387093.SUN_1859	3.2e-67	221.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,42MP3@68525|delta/epsilon subdivisions,2YMP3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
k59_1421650_1	709032.Sulku_1161	1.96e-33	125.0	COG3087@1|root,COG3147@1|root,COG3087@2|Bacteria,COG3147@2|Bacteria,1MYFG@1224|Proteobacteria,42X9Q@68525|delta/epsilon subdivisions	1224|Proteobacteria	D	Sporulation related domain	ftsN	-	-	ko:K03591,ko:K03749	-	-	-	-	ko00000,ko03036	-	-	-	SPOR
k59_482595_1	387093.SUN_0631	3.44e-97	285.0	COG0235@1|root,COG0235@2|Bacteria,1N84G@1224|Proteobacteria,42RVW@68525|delta/epsilon subdivisions,2YP4S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
k59_542150_1	709032.Sulku_0720	3.85e-30	122.0	COG1450@1|root,COG1450@2|Bacteria,1MVNC@1224|Proteobacteria,43BJ2@68525|delta/epsilon subdivisions,2YN49@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Type II and III secretion system protein	ctsD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	STN,Secretin,Secretin_N_2
k59_1713761_1	1249480.B649_02875	7.18e-55	173.0	COG0594@1|root,COG0594@2|Bacteria,1NGQJ@1224|Proteobacteria,42U9K@68525|delta/epsilon subdivisions,2YQ3Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
k59_1423584_1	1304883.KI912532_gene921	3.41e-124	357.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,2VHBM@28216|Betaproteobacteria,2KUUC@206389|Rhodocyclales	206389|Rhodocyclales	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
k59_131949_1	697282.Mettu_1699	8.82e-23	106.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XFYJ@135618|Methylococcales	135618|Methylococcales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GGDEF,PAS_4,PAS_9
k59_1481267_1	948106.AWZT01000074_gene5579	7.36e-111	335.0	COG1463@1|root,COG3008@1|root,COG1463@2|Bacteria,COG3008@2|Bacteria,1MU1T@1224|Proteobacteria,2VJ44@28216|Betaproteobacteria,1K17V@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	MlaD protein	-	-	-	ko:K06192	-	-	-	-	ko00000	-	-	-	MlaD
k59_1303208_1	159087.Daro_1864	2.13e-38	136.0	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2VK14@28216|Betaproteobacteria,2KVP1@206389|Rhodocyclales	206389|Rhodocyclales	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
k59_714489_1	565045.NOR51B_823	2.38e-40	144.0	COG2801@1|root,COG2801@2|Bacteria,1N207@1224|Proteobacteria,1S1FB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_32,LZ_Tnp_IS481,rve,rve_3
k59_774839_1	269799.Gmet_0228	1.01e-31	117.0	COG0428@1|root,COG0428@2|Bacteria,1R76P@1224|Proteobacteria	1224|Proteobacteria	P	Transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
k59_69797_1	1249480.B649_07455	1.7e-60	204.0	COG1315@1|root,COG1315@2|Bacteria,1R5P6@1224|Proteobacteria,42MAS@68525|delta/epsilon subdivisions,2YM7Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Flagellar Assembly Protein A	-	-	-	-	-	-	-	-	-	-	-	-	FapA
k59_544144_1	314345.SPV1_12832	1.35e-27	107.0	COG0834@1|root,COG0834@2|Bacteria,1N3ZN@1224|Proteobacteria	1224|Proteobacteria	ET	COG0840 Methyl-accepting chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	dCache_1
k59_544144_2	94624.Bpet4486	9.31e-11	62.4	2DNXY@1|root,32ZQE@2|Bacteria,1N9C8@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_953640_1	1123368.AUIS01000001_gene1991	9.84e-27	111.0	COG0845@1|root,COG0845@2|Bacteria,1QN99@1224|Proteobacteria,1S0F7@1236|Gammaproteobacteria,2NDZE@225057|Acidithiobacillales	225057|Acidithiobacillales	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
k59_953640_2	864051.BurJ1DRAFT_2141	1.71e-09	58.5	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2VHCZ@28216|Betaproteobacteria,1KJQB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07239,ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1,2.A.6.1.2	-	-	ACR_tran
k59_1013480_1	159087.Daro_2893	3.66e-34	123.0	COG3022@1|root,COG3022@2|Bacteria,1MUAF@1224|Proteobacteria,2VH23@28216|Betaproteobacteria,2KVHY@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the UPF0246 family	-	-	-	ko:K09861	-	-	-	-	ko00000	-	-	-	H2O2_YaaD
k59_69808_1	929558.SMGD1_2122	6.67e-44	160.0	COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42M3W@68525|delta/epsilon subdivisions,2YMI6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	SMART GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GGDEF,PAS_3,PAS_9
k59_893653_1	1231391.AMZF01000013_gene2537	2.36e-14	68.9	COG1132@1|root,COG1132@2|Bacteria,1RDIA@1224|Proteobacteria,2VR6J@28216|Betaproteobacteria,3T4FU@506|Alcaligenaceae	28216|Betaproteobacteria	V	Domain of unknown function (DUF1854)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1854
k59_893653_2	93220.LV28_03610	3.83e-47	168.0	COG0189@1|root,COG0769@1|root,COG0189@2|Bacteria,COG0769@2|Bacteria,1MVN2@1224|Proteobacteria,2WGKZ@28216|Betaproteobacteria,1K6GU@119060|Burkholderiaceae	28216|Betaproteobacteria	HJM	cyanophycin synthetase	cphA2	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	CPSase_L_D2,Mur_ligase_C,Mur_ligase_M,RimK
k59_484435_1	159087.Daro_0451	1.62e-72	227.0	COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,2VI6V@28216|Betaproteobacteria,2KV1J@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
k59_484435_2	1304883.KI912532_gene394	7.1e-51	169.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,2VIFT@28216|Betaproteobacteria,2KUUI@206389|Rhodocyclales	206389|Rhodocyclales	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	sua5	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
k59_1656796_1	1121013.P873_13010	3.72e-21	90.5	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,1RPTA@1236|Gammaproteobacteria,1X30C@135614|Xanthomonadales	135614|Xanthomonadales	M	NAD dependent epimerase dehydratase	-	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase
k59_1656796_2	981327.F925_00642	1.7e-89	275.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,1RMX0@1236|Gammaproteobacteria,3NIGZ@468|Moraxellaceae	1236|Gammaproteobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	wbpO	-	-	ko:K02474	ko00520,map00520	-	R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_1835341_2	709032.Sulku_0461	1.69e-63	194.0	COG0858@1|root,COG0858@2|Bacteria,1Q48R@1224|Proteobacteria,42UQE@68525|delta/epsilon subdivisions,2YPZY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
k59_69845_1	1000565.METUNv1_02454	7.82e-71	234.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2VJ72@28216|Betaproteobacteria,2KVW3@206389|Rhodocyclales	206389|Rhodocyclales	T	CHASE2	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
k59_1481381_1	1249480.B649_09425	2.25e-203	571.0	COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,42M87@68525|delta/epsilon subdivisions,2YNA4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	hemN	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
k59_836049_1	1249480.B649_00045	1.31e-146	427.0	COG0784@1|root,COG5001@1|root,COG0784@2|Bacteria,COG5001@2|Bacteria,1MUNI@1224|Proteobacteria	1224|Proteobacteria	T	COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3369,EAL,GGDEF,Response_reg
k59_836056_1	1168034.FH5T_05560	1.15e-119	353.0	COG3669@1|root,COG3669@2|Bacteria,4NEAP@976|Bacteroidetes,2FM7K@200643|Bacteroidia	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
k59_304856_1	1247726.MIM_c10510	9.98e-29	110.0	COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,2W3M1@28216|Betaproteobacteria	28216|Betaproteobacteria	L	DNA (cytosine-5-)-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_600769_1	1238450.VIBNISOn1_150012	5.27e-18	93.2	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XTC9@135623|Vibrionales	135623|Vibrionales	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
k59_187979_2	1537917.JU82_00885	1.45e-94	286.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,42MN5@68525|delta/epsilon subdivisions,2YN0Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	DUF294,GlnD_UR_UTase,HD,NTP_transf_2
k59_1070296_2	563040.Saut_1428	3.04e-38	140.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,42MAP@68525|delta/epsilon subdivisions,2YNFF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	transporter	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
k59_544263_1	1165841.SULAR_09554	3.52e-96	293.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,42M94@68525|delta/epsilon subdivisions,2YMQM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
k59_1070297_1	563040.Saut_0542	1.68e-40	140.0	2AVG9@1|root,31M8F@2|Bacteria,1QJ39@1224|Proteobacteria,42W1H@68525|delta/epsilon subdivisions,2YQB8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1070297_2	1537917.JU82_09965	8.02e-53	171.0	COG2121@1|root,COG2121@2|Bacteria,1MZID@1224|Proteobacteria,42RJM@68525|delta/epsilon subdivisions,2YP5P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
k59_508094_2	387093.SUN_0191	2.74e-23	89.4	2E91V@1|root,30Y1X@2|Bacteria,1PJX6@1224|Proteobacteria,42XQB@68525|delta/epsilon subdivisions,2YQXZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_687868_1	745411.B3C1_02180	1.28e-22	97.1	COG1757@1|root,COG1757@2|Bacteria,1MY5C@1224|Proteobacteria,1RP6I@1236|Gammaproteobacteria,1J53V@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	C4-dicarboxylate anaerobic carrier	mleN	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
k59_687868_2	1249480.B649_10430	5.46e-16	77.8	COG1757@1|root,COG1757@2|Bacteria,1MY5C@1224|Proteobacteria,42P0P@68525|delta/epsilon subdivisions,2YN3S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Na H antiporter	nhaC	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
k59_978262_1	326298.Suden_1436	3.73e-112	332.0	COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,42MI0@68525|delta/epsilon subdivisions,2YMAS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Small subunit	hydA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.12.5.1	ko:K05927	-	-	-	-	ko00000,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6,TAT_signal
k59_1619361_1	709032.Sulku_0564	1.29e-112	329.0	COG2908@1|root,COG2908@2|Bacteria,1Q1QY@1224|Proteobacteria,42STS@68525|delta/epsilon subdivisions,2YP6A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	protein conserved in bacteria	lpxH	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos
k59_1274964_1	159087.Daro_3407	2.26e-288	797.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,2KUQA@206389|Rhodocyclales	206389|Rhodocyclales	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
k59_625086_1	1304883.KI912532_gene3033	4.83e-100	294.0	COG4660@1|root,COG4660@2|Bacteria,1MW6N@1224|Proteobacteria,2VNWT@28216|Betaproteobacteria,2KU9D@206389|Rhodocyclales	206389|Rhodocyclales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03613	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
k59_1385270_1	1537917.JU82_07430	8.82e-103	309.0	COG3642@1|root,COG3642@2|Bacteria,1NSBH@1224|Proteobacteria,42Q7Z@68525|delta/epsilon subdivisions,2YN3B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	lipopolysaccharide core region biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1861487_1	709032.Sulku_1997	2.22e-68	229.0	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42Z31@68525|delta/epsilon subdivisions,2YRAR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Hpt sensor hybrid histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
k59_1274975_1	1537917.JU82_04320	2.56e-28	103.0	2BR7U@1|root,32K64@2|Bacteria,1Q2P2@1224|Proteobacteria,431JX@68525|delta/epsilon subdivisions,2YSDV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1274975_2	709032.Sulku_1612	5.21e-56	181.0	29DMK@1|root,300JF@2|Bacteria,1Q6BD@1224|Proteobacteria,432QV@68525|delta/epsilon subdivisions,2YSKF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_444451_1	1165841.SULAR_10349	6.42e-150	442.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42M4T@68525|delta/epsilon subdivisions,2YMB2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_1322239_1	639283.Snov_3113	3.14e-42	157.0	COG2989@1|root,COG3170@1|root,COG2989@2|Bacteria,COG3170@2|Bacteria,1MV14@1224|Proteobacteria,2TRJ9@28211|Alphaproteobacteria,3EY0H@335928|Xanthobacteraceae	28211|Alphaproteobacteria	NU	Peptidoglycan-binding domain 1	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
k59_211784_1	1165841.SULAR_08642	1.58e-66	221.0	COG1450@1|root,COG4796@1|root,COG1450@2|Bacteria,COG4796@2|Bacteria,1MUUA@1224|Proteobacteria,42M9I@68525|delta/epsilon subdivisions,2YNRH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	general secretion pathway protein D	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
k59_1385309_1	556267.HWAG_01232	3.73e-13	68.6	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,42KZG@68525|delta/epsilon subdivisions,2YMKQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
k59_979992_1	1537917.JU82_07420	2.72e-12	65.5	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,42MBC@68525|delta/epsilon subdivisions,2YMZG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	hldE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
k59_979992_2	709032.Sulku_2144	1.79e-149	426.0	COG0451@1|root,COG0451@2|Bacteria,1MVE4@1224|Proteobacteria,42MC1@68525|delta/epsilon subdivisions,2YMD0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	ADP-L-glycero-D-manno-heptose-6-epimerase	waaD	-	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase
k59_1323921_1	1304883.KI912532_gene1945	8.2e-74	252.0	COG0517@1|root,COG0642@1|root,COG0784@1|root,COG2198@1|root,COG2202@1|root,COG0517@2|Bacteria,COG0642@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2202@2|Bacteria,1NC9X@1224|Proteobacteria,2WGIN@28216|Betaproteobacteria,2KZWQ@206389|Rhodocyclales	206389|Rhodocyclales	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	CBS,GAF_2,HATPase_c,HisKA,Hpt,PAS_3,Response_reg
k59_322963_1	387093.SUN_1028	4.63e-102	327.0	COG4581@1|root,COG4581@2|Bacteria,1MVD6@1224|Proteobacteria,42PR3@68525|delta/epsilon subdivisions,2YN2Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Mitochondrial degradasome RNA helicase subunit C terminal	-	-	3.6.4.13	ko:K17675	-	-	-	-	ko00000,ko01000,ko03029	-	-	-	Helicase_C,SUV3_C
k59_446137_1	572480.Arnit_1512	4.13e-66	212.0	COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,42MCZ@68525|delta/epsilon subdivisions,2YNNG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	type I secretion membrane fusion protein, HlyD family	-	-	-	ko:K02022,ko:K12542	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	3.A.1.109.4,8.A.1	-	-	Biotin_lipoyl_2,HlyD_3
k59_1323949_1	292415.Tbd_0510	8.44e-26	110.0	COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,2VH52@28216|Betaproteobacteria,1KS47@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Protein of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_2,DUF3971
k59_916014_1	1249480.B649_04325	1.83e-55	190.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,42MXV@68525|delta/epsilon subdivisions,2YRFR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Cyt-b5,POR,POR_N
k59_916014_2	709032.Sulku_1043	7.2e-07	49.7	COG4244@1|root,COG4892@1|root,COG4244@2|Bacteria,COG4892@2|Bacteria	2|Bacteria	S	Cytochrome b5-like Heme/Steroid binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cyt-b5,PSCyt1,PSCyt2,PSD1
k59_1679541_1	709032.Sulku_1830	3.13e-116	350.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,42NAX@68525|delta/epsilon subdivisions,2YN4X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
k59_626856_1	395495.Lcho_2656	3.91e-29	111.0	COG0614@1|root,COG0614@2|Bacteria,1PKNF@1224|Proteobacteria,2VMK5@28216|Betaproteobacteria,1KJ2A@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
k59_213222_1	1120970.AUBZ01000005_gene491	3.84e-151	434.0	COG0208@1|root,COG0208@2|Bacteria,1MWUS@1224|Proteobacteria,1RMJC@1236|Gammaproteobacteria,4649Z@72275|Alteromonadaceae	1236|Gammaproteobacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdB	GO:0003674,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0015949,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990204	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	iAPECO1_1312.APECO1_4325	Ribonuc_red_sm
k59_1795780_1	563040.Saut_1460	3.49e-17	81.3	COG2199@1|root,COG2199@2|Bacteria,1Q2N5@1224|Proteobacteria,42VZ7@68525|delta/epsilon subdivisions,2YQIC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG2199 FOG GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_323044_1	1304883.KI912532_gene1795	8.02e-93	295.0	COG0842@1|root,COG1129@1|root,COG0842@2|Bacteria,COG1129@2|Bacteria,1QTT9@1224|Proteobacteria,2WGGY@28216|Betaproteobacteria,2KVF7@206389|Rhodocyclales	206389|Rhodocyclales	V	ABC-type multidrug transport system, ATPase component	-	-	-	ko:K13926	-	-	-	-	ko00000	-	-	-	ABC2_membrane_3,ABC_tran
k59_1209808_1	944547.ABLL_1709	7.58e-76	241.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,42MAP@68525|delta/epsilon subdivisions,2YNFF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	transporter	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
k59_323063_1	1165841.SULAR_05183	2.01e-118	365.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,42MMV@68525|delta/epsilon subdivisions,2YMV9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k59_1621039_1	929558.SMGD1_1106	3.41e-17	80.5	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,42PKU@68525|delta/epsilon subdivisions,2YPEZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	cation efflux system protein	crdC	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	HlyD_D23,HlyD_D4
k59_1621039_2	563040.Saut_2057	1.06e-59	206.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42NCZ@68525|delta/epsilon subdivisions,2YNKW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	czcA	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
k59_572265_1	709032.Sulku_0796	5.78e-43	146.0	COG2863@1|root,COG2863@2|Bacteria,1NBPD@1224|Proteobacteria,42VXS@68525|delta/epsilon subdivisions,2YQ9N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
k59_1157161_1	1249480.B649_07130	1.55e-68	209.0	COG2010@1|root,COG2010@2|Bacteria,1QZ1X@1224|Proteobacteria,42WCS@68525|delta/epsilon subdivisions,2YQIG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
k59_802454_1	563040.Saut_1223	1.33e-30	124.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42MXI@68525|delta/epsilon subdivisions,2YTK8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
k59_802454_2	903818.KI912268_gene1509	8.17e-22	97.1	COG4206@1|root,COG4206@2|Bacteria	2|Bacteria	H	cobalamin-transporting ATPase activity	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_980171_1	1249480.B649_05680	6.49e-67	208.0	2AIU4@1|root,319B6@2|Bacteria,1Q28N@1224|Proteobacteria,42V6E@68525|delta/epsilon subdivisions,2YQ6D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_856890_1	159087.Daro_1362	1.32e-109	342.0	COG2202@1|root,COG3829@1|root,COG5001@1|root,COG2202@2|Bacteria,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KV9J@206389|Rhodocyclales	206389|Rhodocyclales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,MASE3,PAS,PAS_4,PAS_9
k59_916168_1	709032.Sulku_1114	6.19e-40	142.0	COG2265@1|root,COG2265@2|Bacteria,1MY45@1224|Proteobacteria,43BHX@68525|delta/epsilon subdivisions,2YMEI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA)	trmA	-	2.1.1.35	ko:K00557	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_U5-meth_tr
k59_916168_2	1249480.B649_04660	2.46e-38	142.0	COG3206@1|root,COG3206@2|Bacteria,1Q68V@1224|Proteobacteria,432MZ@68525|delta/epsilon subdivisions,2YSUM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1157178_2	1304883.KI912532_gene1510	8.01e-128	368.0	COG4137@1|root,COG4137@2|Bacteria,1R3YD@1224|Proteobacteria,2VK0H@28216|Betaproteobacteria,2KW12@206389|Rhodocyclales	206389|Rhodocyclales	S	Cytochrome C assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
k59_1738502_1	1121035.AUCH01000001_gene1978	8.87e-19	88.2	COG1305@1|root,COG1305@2|Bacteria,1MWCE@1224|Proteobacteria,2VHZP@28216|Betaproteobacteria,2KV42@206389|Rhodocyclales	206389|Rhodocyclales	E	Domain of unknown function (DUF3488)	-	-	2.3.2.13	ko:K22452	-	-	-	-	ko00000,ko01000	-	-	-	DUF3488,DUF4129,Transglut_core
k59_1863053_1	709032.Sulku_1100	8.39e-87	264.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,42RH7@68525|delta/epsilon subdivisions	1224|Proteobacteria	N	Flagellar motor protein	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
k59_1569496_1	1249480.B649_10255	1.45e-97	286.0	COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,42SB8@68525|delta/epsilon subdivisions,2YPI9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA	gidB	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
k59_1569496_2	1537917.JU82_02625	1.6e-22	88.6	2EHK0@1|root,33BBV@2|Bacteria,1NGIK@1224|Proteobacteria,42WYY@68525|delta/epsilon subdivisions,2YQPD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Prokaryotic metallothionein	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	Metallothio_Pro
k59_1569496_3	709032.Sulku_2173	4.45e-13	64.7	2AK35@1|root,31ASX@2|Bacteria,1Q62J@1224|Proteobacteria,42W2T@68525|delta/epsilon subdivisions,2YQDE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1863054_1	1249480.B649_00030	8.1e-155	454.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria	1224|Proteobacteria	P	Receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_1795854_1	572477.Alvin_1373	1.78e-07	58.2	COG0642@1|root,COG0784@1|root,COG1340@1|root,COG1352@1|root,COG2198@1|root,COG2201@1|root,COG2202@1|root,COG3290@1|root,COG0784@2|Bacteria,COG1340@2|Bacteria,COG1352@2|Bacteria,COG2198@2|Bacteria,COG2201@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3290@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1WXY9@135613|Chromatiales	135613|Chromatiales	T	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	-	-	-	-	-	-	-	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,Hpt,PAS_4,Response_reg
k59_90098_1	990073.ATHU01000001_gene1603	1.21e-66	229.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42MX5@68525|delta/epsilon subdivisions,2YMSQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)	-	-	2.7.7.13,5.4.2.8	ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II
k59_1387029_1	1385515.N791_01665	5.84e-69	219.0	COG1946@1|root,COG1946@2|Bacteria,1MV9R@1224|Proteobacteria,1RPFI@1236|Gammaproteobacteria,1X38E@135614|Xanthomonadales	135614|Xanthomonadales	I	Acyl-CoA thioesterase	tesB	-	-	ko:K10805	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT_3
k59_802492_1	1537917.JU82_02185	7.97e-130	377.0	COG2374@1|root,COG2374@2|Bacteria,1RCTI@1224|Proteobacteria,42Q2J@68525|delta/epsilon subdivisions,2YNG1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
k59_323155_1	1304883.KI912532_gene643	0.000203	43.9	COG0745@1|root,COG4783@1|root,COG0745@2|Bacteria,COG4783@2|Bacteria,1QWFU@1224|Proteobacteria,2WGYB@28216|Betaproteobacteria,2KZWT@206389|Rhodocyclales	206389|Rhodocyclales	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_323155_2	159087.Daro_0144	2.52e-65	212.0	COG1492@1|root,COG1492@2|Bacteria,1MUFY@1224|Proteobacteria,2VII5@28216|Betaproteobacteria,2KUUT@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	CbiA,GATase_3
k59_385199_1	95619.PM1_0221105	4.58e-64	205.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,1RRPI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CE	Tartrate dehydrogenase	yeaU	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003862,GO:0005488,GO:0006082,GO:0006108,GO:0008150,GO:0008152,GO:0009027,GO:0009987,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0019752,GO:0036094,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0046553,GO:0046872,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363	1.1.1.83,1.1.1.93,4.1.1.73	ko:K07246	ko00630,ko00650,map00630,map00650	-	R00215,R01751,R02545,R06180	RC00084,RC00105,RC00594	ko00000,ko00001,ko01000	-	-	iSBO_1134.SBO_1288	Iso_dh
k59_509989_1	1537917.JU82_03770	8.3e-93	303.0	COG1195@1|root,COG5295@1|root,COG1195@2|Bacteria,COG5295@2|Bacteria,1R0Y3@1224|Proteobacteria,42NCY@68525|delta/epsilon subdivisions,2YN22@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_856925_1	1165841.SULAR_06813	2.96e-91	271.0	COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,42QQP@68525|delta/epsilon subdivisions,2YNZZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
k59_1209917_1	997884.HMPREF1068_02841	1.06e-19	93.6	COG0534@1|root,COG0534@2|Bacteria,4NFIR@976|Bacteroidetes,2FMSA@200643|Bacteroidia,4AN4V@815|Bacteroidaceae	976|Bacteroidetes	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
k59_1621140_1	159087.Daro_0527	2.15e-42	152.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,2VHI9@28216|Betaproteobacteria,2KUN3@206389|Rhodocyclales	206389|Rhodocyclales	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_4,Toprim_N,zf-CHC2
k59_1738595_1	1537917.JU82_02910	8.4e-92	275.0	28M05@1|root,2ZAF9@2|Bacteria,1MY5U@1224|Proteobacteria,42QPW@68525|delta/epsilon subdivisions,2YP0Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	General glycosylation pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_269960_1	1249480.B649_09845	2.3e-126	369.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2YNF8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	flgR	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_1503015_1	1249480.B649_11360	2.27e-103	327.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YMHP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF,PAS_4
k59_1863122_2	709032.Sulku_0284	2.2e-62	198.0	COG1434@1|root,COG1434@2|Bacteria,1MVW8@1224|Proteobacteria,42SRW@68525|delta/epsilon subdivisions,2YPFX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
k59_1863127_1	1249480.B649_03255	2.36e-115	341.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,42MMB@68525|delta/epsilon subdivisions,2YMVM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
k59_1503043_1	1537917.JU82_08245	8.9e-80	248.0	COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,42MBN@68525|delta/epsilon subdivisions,2YMCS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
k59_1503044_1	375286.mma_2192	8.75e-28	116.0	2ES6Y@1|root,33JRQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1738680_1	247156.NFA_13060	3.24e-95	312.0	COG2902@1|root,COG2902@2|Bacteria,2GK0C@201174|Actinobacteria,4FVGF@85025|Nocardiaceae	201174|Actinobacteria	E	glutamate dehydrogenase	-	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
k59_510085_1	1304883.KI912532_gene2600	1.64e-101	315.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,2VHTX@28216|Betaproteobacteria,2KV13@206389|Rhodocyclales	206389|Rhodocyclales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_916339_1	1537917.JU82_05620	9.6e-127	370.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,42M0T@68525|delta/epsilon subdivisions,2YMEX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0183	SHMT
k59_446425_1	326298.Suden_0220	3.92e-44	162.0	COG2199@1|root,COG3706@2|Bacteria,1QZ1Q@1224|Proteobacteria,43AM7@68525|delta/epsilon subdivisions,2YR58@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Protein of unknown function (DUF3365)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,GGDEF
k59_323249_1	1249480.B649_04385	1.2e-123	365.0	COG2895@1|root,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,42N3C@68525|delta/epsilon subdivisions,2YNS9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_EFTU
k59_270000_1	709032.Sulku_1983	5.73e-71	220.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,42N5B@68525|delta/epsilon subdivisions,2YMWV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
k59_32350_2	388467.A19Y_4547	5.27e-28	118.0	COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,1G16R@1117|Cyanobacteria,1H85V@1150|Oscillatoriales	1117|Cyanobacteria	C	belongs to the CobB CobQ family	pta	-	2.3.1.8	ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,DRTGG,PTA_PTB
k59_1387174_1	709032.Sulku_1318	2.26e-118	345.0	COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,42R55@68525|delta/epsilon subdivisions,2YNS0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
k59_1094410_1	1537917.JU82_05085	2.32e-103	303.0	COG4123@1|root,COG4123@2|Bacteria,1R0S2@1224|Proteobacteria,42UPG@68525|delta/epsilon subdivisions,2YPXV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,TehB
k59_1094410_2	1249480.B649_11765	2.62e-13	68.9	COG0144@1|root,COG0144@2|Bacteria,1MWPE@1224|Proteobacteria,42P2T@68525|delta/epsilon subdivisions,2YNNR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N
k59_1738716_1	1537917.JU82_10805	3.6e-94	283.0	COG1672@1|root,COG1672@2|Bacteria,1PMVJ@1224|Proteobacteria,42PCP@68525|delta/epsilon subdivisions,2YNZF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM Archaea bacterial proteins of	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	DUF234
k59_916355_1	1168067.JAGP01000001_gene1439	6.35e-155	443.0	COG0158@1|root,COG0158@2|Bacteria,1MW0E@1224|Proteobacteria,1RNFF@1236|Gammaproteobacteria,461SY@72273|Thiotrichales	72273|Thiotrichales	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1	fbp	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
k59_916355_2	1045856.EcWSU1_00427	5.8e-78	236.0	COG0221@1|root,COG0221@2|Bacteria,1RA2F@1224|Proteobacteria,1RPVD@1236|Gammaproteobacteria,3X200@547|Enterobacter	1236|Gammaproteobacteria	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	GO:0000287,GO:0003674,GO:0003824,GO:0004427,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006793,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050355	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	iJN746.PP_0538,iPC815.YPO3521	Pyrophosphatase
k59_385296_2	709032.Sulku_1558	5.17e-85	259.0	COG2301@1|root,COG2301@2|Bacteria,1NUDQ@1224|Proteobacteria,42QUW@68525|delta/epsilon subdivisions,2YNZV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the HpcH HpaI aldolase family	citE	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
k59_1276998_1	159087.Daro_3480	1.6e-100	299.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,2VJ5G@28216|Betaproteobacteria,2KUAX@206389|Rhodocyclales	206389|Rhodocyclales	M	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
k59_1863179_1	159087.Daro_3183	8.19e-30	109.0	COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,2VSE2@28216|Betaproteobacteria,2KWMK@206389|Rhodocyclales	206389|Rhodocyclales	H	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
k59_1863179_2	159087.Daro_3184	2.68e-78	233.0	COG3169@1|root,COG3169@2|Bacteria,1RHBQ@1224|Proteobacteria,2VSWS@28216|Betaproteobacteria,2KWRH@206389|Rhodocyclales	206389|Rhodocyclales	S	protein conserved in bacteria	-	-	-	ko:K09922	-	-	-	-	ko00000	-	-	-	DMT_6
k59_56225_1	1249480.B649_07405	1.35e-86	275.0	COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,42MP9@68525|delta/epsilon subdivisions,2YMN8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Type I secretion system ATPase	-	-	-	ko:K12541	ko02010,map02010	M00330	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.109.3,3.A.1.109.4	-	-	ABC_membrane,ABC_tran
k59_114954_1	1165841.SULAR_09859	1.19e-59	195.0	COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,42MGS@68525|delta/epsilon subdivisions,2YMUK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
k59_114954_2	1165841.SULAR_09864	7.31e-19	85.1	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,42MEF@68525|delta/epsilon subdivisions,2YMMY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Aminotransferase	-	-	-	ko:K14261	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_759072_1	247634.GPB2148_2237	1.5e-13	70.9	28I89@1|root,2Z8B3@2|Bacteria,1R84E@1224|Proteobacteria,1RY7X@1236|Gammaproteobacteria,1JA66@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	EpsG family	-	-	-	-	-	-	-	-	-	-	-	-	EpsG
k59_759072_2	367737.Abu_0678	1.05e-46	166.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,42MEI@68525|delta/epsilon subdivisions,2YND5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	asparagine	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_115336_1	426117.M446_2137	6.5e-19	90.1	COG0457@1|root,COG0457@2|Bacteria,1NA2B@1224|Proteobacteria,2UGJP@28211|Alphaproteobacteria,1JR5K@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	SGNH hydrolase-like domain, acetyltransferase AlgX	-	-	-	-	-	-	-	-	-	-	-	-	ALGX
k59_115509_2	159087.Daro_0100	1.22e-102	306.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VHD3@28216|Betaproteobacteria,2KVRR@206389|Rhodocyclales	206389|Rhodocyclales	C	Acyl-CoA dehydrogenase, C-terminal domain	acd	-	1.3.8.4	ko:K00253	ko00280,ko01100,map00280,map01100	M00036	R04095	RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_759315_1	1408433.JHXV01000020_gene3528	2.64e-128	381.0	COG0422@1|root,COG0422@2|Bacteria,4NFTF@976|Bacteroidetes,1HZ6B@117743|Flavobacteriia,2PBAB@246874|Cryomorphaceae	976|Bacteroidetes	H	ThiC-associated domain	thiC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
k59_115542_1	709032.Sulku_1783	9.21e-99	307.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2YMAM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,Response_reg
k59_56775_1	709032.Sulku_1478	7.11e-107	331.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,42MMV@68525|delta/epsilon subdivisions,2YMV9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k59_759438_1	159087.Daro_0017	4.36e-31	116.0	COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,2VIBJ@28216|Betaproteobacteria,2KVAT@206389|Rhodocyclales	206389|Rhodocyclales	K	Transcriptional regulator	-	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
k59_759438_2	159087.Daro_0016	1.84e-92	274.0	COG1187@1|root,COG1187@2|Bacteria,1MU6M@1224|Proteobacteria,2VIXH@28216|Betaproteobacteria,2KV6A@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the pseudouridine synthase RsuA family	rsuA	-	5.4.99.19	ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_56822_1	1537917.JU82_09780	2.35e-74	241.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42YH8@68525|delta/epsilon subdivisions,2YRAU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
k59_115699_1	159087.Daro_1414	1.14e-192	543.0	COG2710@1|root,COG2710@2|Bacteria,1MVY2@1224|Proteobacteria,2VHMG@28216|Betaproteobacteria,2KVM9@206389|Rhodocyclales	206389|Rhodocyclales	C	Nitrogenase component 1 type Oxidoreductase	-	-	1.18.6.1	ko:K02586	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_nitro
k59_115715_1	497321.C664_04582	9e-16	74.7	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,2VJVA@28216|Betaproteobacteria,2KVMT@206389|Rhodocyclales	206389|Rhodocyclales	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
k59_115715_2	159087.Daro_0383	3.21e-73	225.0	COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,2VI5G@28216|Betaproteobacteria,2KYHZ@206389|Rhodocyclales	206389|Rhodocyclales	I	enoyl-CoA hydratase	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
k59_56928_1	159087.Daro_0939	5.36e-116	360.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,2VI4A@28216|Betaproteobacteria,2KUXH@206389|Rhodocyclales	206389|Rhodocyclales	EF	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_759708_1	1123517.JOMR01000001_gene272	9.67e-34	134.0	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,4608A@72273|Thiotrichales	72273|Thiotrichales	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,PAS_4,Response_reg
k59_759740_1	709032.Sulku_0751	1.11e-44	150.0	COG0340@1|root,COG0340@2|Bacteria,1Q1NZ@1224|Proteobacteria,42RQM@68525|delta/epsilon subdivisions,2YP5C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	biotin acetyl-CoA-carboxylase ligase	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_LplA_LipB
k59_759740_2	1537917.JU82_04605	2.56e-174	487.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,42MTF@68525|delta/epsilon subdivisions,2YMZQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	involved in chromosome partitioning	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
k59_116022_1	159087.Daro_3411	1.01e-37	131.0	2AH03@1|root,3178V@2|Bacteria,1PYIT@1224|Proteobacteria,2WDQZ@28216|Betaproteobacteria,2KZD8@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_57116_1	1254432.SCE1572_37590	5.01e-31	124.0	COG3202@1|root,COG3202@2|Bacteria,1MVP5@1224|Proteobacteria,438CB@68525|delta/epsilon subdivisions,2X3MN@28221|Deltaproteobacteria,2YWIY@29|Myxococcales	28221|Deltaproteobacteria	C	ATP ADP translocase	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	-
k59_759865_1	1304888.ATWF01000001_gene1049	2.1e-16	77.4	2BN8J@1|root,32GW0@2|Bacteria,2GFHQ@200930|Deferribacteres	200930|Deferribacteres	S	LPP20 lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	LPP20
k59_759868_1	1123325.JHUV01000012_gene959	6.59e-101	302.0	COG1087@1|root,COG1087@2|Bacteria,2G3QB@200783|Aquificae	200783|Aquificae	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
k59_61003_2	1442598.JABW01000006_gene687	1.28e-70	218.0	COG0386@1|root,COG0386@2|Bacteria,1RD1R@1224|Proteobacteria,42S35@68525|delta/epsilon subdivisions,2YRQI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Glutathione peroxidase	-	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
k59_61003_3	1249480.B649_04535	2.23e-45	153.0	COG1659@1|root,COG1659@2|Bacteria,1QKHQ@1224|Proteobacteria,42UCA@68525|delta/epsilon subdivisions,2YSD1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Encapsulating protein for peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	Linocin_M18
k59_1000287_1	1485545.JQLW01000005_gene1024	7.84e-09	54.7	2DMKI@1|root,32S70@2|Bacteria,1N1FV@1224|Proteobacteria	1224|Proteobacteria	S	SpoIIAA-like	VVA0543	-	-	-	-	-	-	-	-	-	-	-	SpoIIAA-like
k59_1000287_2	709032.Sulku_1096	1.69e-59	186.0	COG1846@1|root,COG1846@2|Bacteria,1Q5M6@1224|Proteobacteria,431G7@68525|delta/epsilon subdivisions,2YS5F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1058632_1	1165841.SULAR_02428	9.51e-33	120.0	COG4902@1|root,COG4902@2|Bacteria	2|Bacteria	-	-	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	DUF2202
k59_824244_1	1304883.KI912532_gene276	7.74e-124	363.0	COG0548@1|root,COG1246@1|root,COG0548@2|Bacteria,COG1246@2|Bacteria,1MUUP@1224|Proteobacteria,2VGZC@28216|Betaproteobacteria,2KUN4@206389|Rhodocyclales	206389|Rhodocyclales	E	Belongs to the acetyltransferase family. ArgA subfamily	argA	-	2.3.1.1	ko:K14682	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,Acetyltransf_1
k59_472125_1	1249480.B649_11660	3.38e-85	260.0	COG2956@1|root,COG2956@2|Bacteria,1QUIS@1224|Proteobacteria,42M7G@68525|delta/epsilon subdivisions,2YMKN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_7,TPR_8
k59_472125_3	1249480.B649_11650	4.51e-17	79.7	COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,42MYF@68525|delta/epsilon subdivisions,2YMXD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Single-stranded-DNA-specific exonuclease (RecJ)	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
k59_237125_1	675816.VIA_001939	1.33e-33	121.0	COG3806@1|root,COG3806@2|Bacteria,1R52I@1224|Proteobacteria,1RNI5@1236|Gammaproteobacteria,1XVGP@135623|Vibrionales	135623|Vibrionales	T	ChrR Cupin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_7
k59_237125_2	90814.KL370892_gene1953	1.92e-76	234.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,1RMT6@1236|Gammaproteobacteria,460EA@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
k59_941667_1	1249480.B649_05160	7.15e-95	281.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42S2J@68525|delta/epsilon subdivisions	1224|Proteobacteria	V	abc transporter atp-binding protein	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_1352186_2	709032.Sulku_2353	5.43e-20	89.4	COG3334@1|root,COG3334@2|Bacteria,1Q9SM@1224|Proteobacteria,42TJV@68525|delta/epsilon subdivisions,2YPUS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PDP protein	-	-	-	-	-	-	-	-	-	-	-	-	MgtE_N
k59_61035_1	765912.Thimo_1827	4.97e-80	257.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,1RPFB@1236|Gammaproteobacteria,1WW67@135613|Chromatiales	135613|Chromatiales	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
k59_1469466_1	1562701.BBOF01000034_gene1027	0.000229	42.7	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,2VHBM@28216|Betaproteobacteria,1K26W@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
k59_1469466_2	159087.Daro_4118	3.41e-88	259.0	COG3536@1|root,COG3536@2|Bacteria,1MZ5M@1224|Proteobacteria,2VR9K@28216|Betaproteobacteria,2KWB0@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF971
k59_1469466_3	159087.Daro_4119	5.63e-05	44.7	2A8Z1@1|root,30Y2U@2|Bacteria,1PJYG@1224|Proteobacteria,2VJ83@28216|Betaproteobacteria,2KVGT@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_648592_1	1537917.JU82_02565	6.93e-160	465.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,42MNH@68525|delta/epsilon subdivisions,2YMIP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C
k59_472155_1	1165841.SULAR_04798	1.45e-107	330.0	COG0046@1|root,COG0046@2|Bacteria,1MYN4@1224|Proteobacteria,42M08@68525|delta/epsilon subdivisions,2YMHZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
k59_1235130_1	159087.Daro_0744	1.33e-53	174.0	COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,2VNCG@28216|Betaproteobacteria,2KV2Y@206389|Rhodocyclales	206389|Rhodocyclales	N	flagellar motor	motC	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
k59_1235130_2	159087.Daro_0745	1.67e-98	292.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,2VKC4@28216|Betaproteobacteria,2KV6P@206389|Rhodocyclales	206389|Rhodocyclales	N	Flagellar motor protein	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
k59_1293837_1	1500894.JQNN01000001_gene3511	5.51e-107	331.0	COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,2VH6A@28216|Betaproteobacteria,472U8@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	Likely ribonuclease with RNase H fold.	tex	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
k59_1117558_1	268748.Q58N40_BPPRP	4.56e-28	110.0	4QAM2@10239|Viruses,4QV3W@35237|dsDNA viruses  no RNA stage,4QPGK@28883|Caudovirales,4QNW0@10744|Podoviridae	10744|Podoviridae	S	exonuclease activity	-	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360	-	-	-	-	-	-	-	-	-	-	-
k59_824324_1	929558.SMGD1_2812	9.39e-26	108.0	COG1807@1|root,COG1807@2|Bacteria,1P6JE@1224|Proteobacteria,42Z03@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
k59_1587617_1	159087.Daro_0140	2.3e-100	298.0	COG1270@1|root,COG1270@2|Bacteria,1MURM@1224|Proteobacteria,2VIDF@28216|Betaproteobacteria,2KUAV@206389|Rhodocyclales	206389|Rhodocyclales	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	-	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
k59_178040_2	1000565.METUNv1_01524	2.2e-136	396.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2VHJP@28216|Betaproteobacteria,2KV2N@206389|Rhodocyclales	206389|Rhodocyclales	G	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	ko:K11690	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctM
k59_824332_1	985867.AEWF01000001_gene2319	4.94e-14	78.2	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,2TUH6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG0659 Sulfate permease and related transporters (MFS superfamily	sulP	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k59_1235182_1	1249480.B649_09050	5.08e-151	449.0	COG0457@1|root,COG0457@2|Bacteria,1QV15@1224|Proteobacteria,42NKI@68525|delta/epsilon subdivisions,2YMKG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	COG0457 FOG TPR repeat	pflB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_6,TPR_8
k59_706503_1	159087.Daro_1932	7.89e-100	302.0	COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,2VGZY@28216|Betaproteobacteria,2KVJY@206389|Rhodocyclales	206389|Rhodocyclales	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
k59_1117606_1	1249480.B649_07390	1.03e-105	344.0	COG2304@1|root,COG4932@1|root,COG5295@1|root,COG2304@2|Bacteria,COG4932@2|Bacteria,COG5295@2|Bacteria,1QU09@1224|Proteobacteria,43DI2@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,HemolysinCabind,VWA_2
k59_1469561_1	983545.Glaag_0977	2.79e-55	184.0	COG0739@1|root,COG0739@2|Bacteria,1MY2X@1224|Proteobacteria,1RMYN@1236|Gammaproteobacteria,466FY@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_1352300_1	709032.Sulku_1748	2.22e-73	226.0	COG4123@1|root,COG4123@2|Bacteria,1RDSC@1224|Proteobacteria,42RIN@68525|delta/epsilon subdivisions,2YP8V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	MTS
k59_413295_2	1537917.JU82_09305	2.33e-17	76.3	COG0483@1|root,COG0483@2|Bacteria	2|Bacteria	G	inositol monophosphate 1-phosphatase activity	suhB	-	3.1.3.25,3.1.3.7	ko:K01082,ko:K01092	ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070	M00131	R00188,R00508,R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	Inositol_P
k59_531269_1	1123236.KB899378_gene1677	1.14e-07	53.1	COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,1RN1J@1236|Gammaproteobacteria,466F3@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
k59_531269_2	398767.Glov_0561	8.59e-06	50.8	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,42QZ1@68525|delta/epsilon subdivisions,2WKYF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_1587690_1	744980.TRICHSKD4_5691	4.51e-14	70.9	COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,2TSJV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site	rbcL	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
k59_1587690_2	580332.Slit_0986	3.41e-80	238.0	COG4451@1|root,COG4451@2|Bacteria,1R9ZE@1224|Proteobacteria,2VRRB@28216|Betaproteobacteria,44WEJ@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Ribulose bisphosphate carboxylase, small chain	cbbS	-	4.1.1.39	ko:K01602	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_small
k59_1058783_1	1537917.JU82_07430	2.28e-31	120.0	COG3642@1|root,COG3642@2|Bacteria,1NSBH@1224|Proteobacteria,42Q7Z@68525|delta/epsilon subdivisions,2YN3B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	lipopolysaccharide core region biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1058783_2	1537917.JU82_07435	2.94e-28	109.0	COG0859@1|root,COG0859@2|Bacteria,1N5A1@1224|Proteobacteria,42S5Z@68525|delta/epsilon subdivisions,2YP6I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG0859 ADP-heptose LPS heptosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
k59_1822784_1	1123371.ATXH01000002_gene364	6.69e-39	144.0	COG1085@1|root,COG1085@2|Bacteria,2GIAD@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	Galactose-1-phosphate uridyl transferase, C-terminal domain	-	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
k59_941856_1	709032.Sulku_1961	1.74e-18	86.3	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,430EJ@68525|delta/epsilon subdivisions,2YRYU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
k59_354353_1	243233.MCA0979	5.58e-64	207.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,1SZ12@1236|Gammaproteobacteria,1XGAN@135618|Methylococcales	135618|Methylococcales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
k59_3275_1	472759.Nhal_0862	4.16e-58	184.0	COG1765@1|root,COG1765@2|Bacteria,1RCZW@1224|Proteobacteria,1S3XF@1236|Gammaproteobacteria,1WY24@135613|Chromatiales	135613|Chromatiales	O	redox protein, regulator of disulfide bond formation	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
k59_3275_2	1191460.F959_02575	1.89e-08	55.1	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,1RNYH@1236|Gammaproteobacteria,3NJGD@468|Moraxellaceae	1236|Gammaproteobacteria	E	Belongs to the TrpC family	trpC	GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	iJN746.PP_0422	IGPS
k59_1000473_1	1719.CPTC_00923	3.8e-21	91.7	COG1136@1|root,COG1136@2|Bacteria,2GK3I@201174|Actinobacteria,22KC2@1653|Corynebacteriaceae	201174|Actinobacteria	V	ABC transporter, ATP-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_1000473_2	207954.MED92_13823	3.66e-25	105.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1XHW5@135619|Oceanospirillales	135619|Oceanospirillales	T	Chemotaxis protein histidine kinase and related	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,CheY-binding,H-kinase_dim,HATPase_c,Hpt
k59_531313_1	159087.Daro_3948	8.22e-16	73.2	COG2151@1|root,COG2151@2|Bacteria,1MZ9Y@1224|Proteobacteria,2VUA0@28216|Betaproteobacteria,2KWX5@206389|Rhodocyclales	206389|Rhodocyclales	S	Pfam:DUF59	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
k59_3288_1	1117314.PCIT_15590	3.44e-23	104.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,1RMCY@1236|Gammaproteobacteria,2Q1NJ@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019904,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
k59_1529228_1	709032.Sulku_0302	8.57e-116	338.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,42P7F@68525|delta/epsilon subdivisions,2YNFY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
k59_472342_1	1249480.B649_06950	2.06e-48	156.0	COG0347@1|root,COG0347@2|Bacteria	2|Bacteria	K	Belongs to the P(II) protein family	glnB	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
k59_1763645_1	709032.Sulku_0882	3.91e-102	306.0	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,42N01@68525|delta/epsilon subdivisions,2YMG2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
k59_706584_1	1304885.AUEY01000052_gene1549	1.4e-06	50.4	2CCD9@1|root,2ZWK6@2|Bacteria	2|Bacteria	S	YtkA-like	-	-	-	-	-	-	-	-	-	-	-	-	YtkA
k59_472348_1	159087.Daro_2872	1.12e-111	333.0	COG3203@1|root,COG3203@2|Bacteria,1Q1XX@1224|Proteobacteria,2VRRG@28216|Betaproteobacteria,2KVVA@206389|Rhodocyclales	206389|Rhodocyclales	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
k59_1058836_1	1537917.JU82_05490	1.71e-50	162.0	COG1146@1|root,COG1146@2|Bacteria,1NJJD@1224|Proteobacteria,42TVE@68525|delta/epsilon subdivisions,2YPUN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	2-oxoglutarate acceptor oxidoreductase	oorD	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Fer4_6,Fer4_7
k59_1058836_2	387093.SUN_0579	1.02e-71	226.0	COG0674@1|root,COG0674@2|Bacteria,1NBSJ@1224|Proteobacteria,42MS1@68525|delta/epsilon subdivisions,2YMD2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Oxidoreductase	oorA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
k59_1117751_1	709032.Sulku_0217	1.42e-120	363.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,42SPZ@68525|delta/epsilon subdivisions,2YMS1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	fdhF	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_1117751_2	1537917.JU82_08930	8.83e-28	102.0	COG0792@1|root,COG0792@2|Bacteria,1Q27V@1224|Proteobacteria,42V4E@68525|delta/epsilon subdivisions,2YQJM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
k59_547150_1	159087.Daro_2026	2.24e-148	432.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,2VHM5@28216|Betaproteobacteria,2KVPJ@206389|Rhodocyclales	206389|Rhodocyclales	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
k59_425876_1	387093.SUN_0965	3.04e-56	184.0	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,42P2E@68525|delta/epsilon subdivisions,2YNPW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
k59_1483838_1	159087.Daro_1125	7.63e-59	182.0	2E4QE@1|root,32ZIZ@2|Bacteria,1NCEP@1224|Proteobacteria,2VU6H@28216|Betaproteobacteria,2KX56@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1483838_2	159087.Daro_1124	3.32e-21	84.3	COG5481@1|root,COG5481@2|Bacteria,1PU51@1224|Proteobacteria,2VXCJ@28216|Betaproteobacteria,2KXHJ@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF465)	-	-	-	-	-	-	-	-	-	-	-	-	DUF465
k59_190259_1	402777.KB235903_gene1174	4.35e-24	107.0	COG5001@1|root,COG5001@2|Bacteria,1G3BI@1117|Cyanobacteria,1HEEG@1150|Oscillatoriales	1117|Cyanobacteria	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_4
k59_1189182_1	1249480.B649_07510	2.46e-95	300.0	COG5001@1|root,COG5001@2|Bacteria,1R4H0@1224|Proteobacteria,43CII@68525|delta/epsilon subdivisions,2YTD5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_716283_2	1537917.JU82_01925	5.28e-19	85.1	COG0790@1|root,COG0790@2|Bacteria,1NY7Z@1224|Proteobacteria,42T5I@68525|delta/epsilon subdivisions,2YPQ5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COG0790 FOG TPR repeat, SEL1 subfamily	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
k59_1544590_1	709032.Sulku_0946	2.96e-109	321.0	COG1633@1|root,COG1633@2|Bacteria,1Q0JN@1224|Proteobacteria,42S76@68525|delta/epsilon subdivisions,2YP4Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1016821_2	1537917.JU82_02155	3.9e-66	207.0	COG0124@1|root,COG0124@2|Bacteria,1QUJQ@1224|Proteobacteria,42NX2@68525|delta/epsilon subdivisions,2YN2F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	PFAM tRNA synthetase class II (G H P and S)	hisZ	-	-	-	-	-	-	-	-	-	-	-	tRNA-synt_His
k59_1838259_1	90813.JQMT01000001_gene1636	1.72e-90	285.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,4608D@72273|Thiotrichales	72273|Thiotrichales	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
k59_1072904_1	1165841.SULAR_05493	2.34e-55	184.0	COG0477@1|root,COG2814@2|Bacteria,1QRUM@1224|Proteobacteria,42MFJ@68525|delta/epsilon subdivisions,2YMW9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EGP	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_1072904_2	1165841.SULAR_05548	5.18e-14	68.2	COG0221@1|root,COG0221@2|Bacteria,1RA2F@1224|Proteobacteria,42MQB@68525|delta/epsilon subdivisions,2YM8X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
k59_425920_1	1249480.B649_06520	5.76e-52	184.0	COG2199@1|root,COG4191@1|root,COG3706@2|Bacteria,COG4191@2|Bacteria,1QYD2@1224|Proteobacteria,42PVI@68525|delta/epsilon subdivisions,2YNV3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_3,PAS_9
k59_603458_1	1537917.JU82_11865	6.93e-111	336.0	COG2199@1|root,COG3706@2|Bacteria,1MXAW@1224|Proteobacteria,42M6B@68525|delta/epsilon subdivisions,2YN3C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_250599_1	709032.Sulku_0182	9.2e-122	353.0	COG0492@1|root,COG0492@2|Bacteria,1NDW6@1224|Proteobacteria,42MUD@68525|delta/epsilon subdivisions,2YMV2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	pyridine nucleotide-disulfide oxidoreductase	trxB_2	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	FixS,Pyr_redox_3
k59_1251464_1	1165841.SULAR_00085	4.37e-66	216.0	COG1538@1|root,COG1538@2|Bacteria,1QWWG@1224|Proteobacteria,42PH5@68525|delta/epsilon subdivisions,2YMHH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_1717722_2	375286.mma_0064	1.55e-23	96.3	COG1192@1|root,COG1192@2|Bacteria,1N3GB@1224|Proteobacteria,2VSGK@28216|Betaproteobacteria,473WT@75682|Oxalobacteraceae	28216|Betaproteobacteria	D	ATPase MipZ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
k59_1544657_1	1537917.JU82_00940	7.97e-155	456.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,42M6W@68525|delta/epsilon subdivisions,2YN2C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	spoT	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT,HD_4,RelA_SpoT,TGS
k59_135060_2	1123517.JOMR01000001_gene1506	1.79e-37	145.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,1RN9H@1236|Gammaproteobacteria,45ZU0@72273|Thiotrichales	72273|Thiotrichales	M	Catalyzes cross-linking of the peptidoglycan cell wall	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
k59_366347_1	709032.Sulku_0961	2.05e-164	466.0	COG0019@1|root,COG0019@2|Bacteria,1MW3T@1224|Proteobacteria,42MVP@68525|delta/epsilon subdivisions,2YMY4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the Orn Lys Arg decarboxylase class-II family. NspC subfamily	nspC	-	4.1.1.96	ko:K13747	ko00330,ko01100,map00330,map01100	-	R09081,R09082	RC00299	ko00000,ko00001,ko01000	-	-	-	Orn_DAP_Arg_deC
k59_1252904_1	1249480.B649_09665	8.25e-211	595.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,42M4S@68525|delta/epsilon subdivisions,2YM8Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	-	-	1.12.5.1	ko:K05922	-	-	-	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
k59_548669_1	62928.azo2326	3.1e-76	246.0	COG2199@1|root,COG2199@2|Bacteria,1R3XS@1224|Proteobacteria,2VNNY@28216|Betaproteobacteria,2KVXR@206389|Rhodocyclales	206389|Rhodocyclales	T	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HAMP,dCache_1
k59_136397_1	1249480.B649_00735	9.98e-113	325.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,42REG@68525|delta/epsilon subdivisions,2YP63@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
k59_136397_2	1249480.B649_00740	3.05e-37	131.0	COG3637@1|root,COG3637@2|Bacteria,1R3QN@1224|Proteobacteria,42Y1W@68525|delta/epsilon subdivisions,2YQU0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_840054_2	580332.Slit_2303	2.6e-53	176.0	29IJE@1|root,305GN@2|Bacteria,1RGAS@1224|Proteobacteria,2VTQX@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_957778_1	709032.Sulku_1812	5.36e-78	239.0	COG0697@1|root,COG0697@2|Bacteria,1PIFB@1224|Proteobacteria,42QAN@68525|delta/epsilon subdivisions,2YNGI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EG	integral membrane protein (DUF6 domain protein)	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_604755_1	1249480.B649_03245	4e-184	515.0	COG2204@1|root,COG2204@2|Bacteria,1QUIV@1224|Proteobacteria,42M4N@68525|delta/epsilon subdivisions,2YMIT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_426983_2	1370121.AUWS01000008_gene5582	5.69e-11	73.6	2DUBA@1|root,33PSU@2|Bacteria,2IKGT@201174|Actinobacteria	201174|Actinobacteria	S	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
k59_426983_6	1463856.JOHY01000097_gene1736	0.000178	48.1	COG3409@1|root,COG3409@2|Bacteria,2HBCJ@201174|Actinobacteria	201174|Actinobacteria	M	Zinc D-Ala-D-Ala carboxypeptidase	-	-	3.4.17.14	ko:K08640	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	PG_binding_1,Peptidase_M15_3
k59_426983_8	1042163.BRLA_c031420	8.61e-27	112.0	COG1846@1|root,COG1846@2|Bacteria,1UNNM@1239|Firmicutes,4IUIW@91061|Bacilli	91061|Bacilli	K	Conserved phage C-terminus (Phg_2220_C)	-	-	-	-	-	-	-	-	-	-	-	-	Phage_rep_org_N,Phg_2220_C
k59_367365_2	187272.Mlg_0363	6.69e-27	110.0	COG0548@1|root,COG1246@1|root,COG0548@2|Bacteria,COG1246@2|Bacteria,1MUUP@1224|Proteobacteria,1RMV5@1236|Gammaproteobacteria,1WX9B@135613|Chromatiales	135613|Chromatiales	E	Belongs to the acetyltransferase family. ArgA subfamily	argA	-	2.3.1.1	ko:K14682	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,Acetyltransf_1
k59_1485065_1	580332.Slit_2654	1.95e-41	144.0	COG2993@1|root,COG2993@2|Bacteria,1NU9D@1224|Proteobacteria	1224|Proteobacteria	C	Cytochrome C oxidase, mono-heme subunit/FixO	-	-	-	-	-	-	-	-	-	-	-	-	FixO
k59_1485065_2	580332.Slit_2655	9.92e-49	167.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,2VIWB@28216|Betaproteobacteria,44V6A@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM cytochrome c oxidase subunit I	-	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
k59_488817_1	709032.Sulku_2491	1.22e-121	374.0	COG0243@1|root,COG0243@2|Bacteria,1NSXR@1224|Proteobacteria,43BQI@68525|delta/epsilon subdivisions,2YRHF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	ko:K17050	-	-	-	-	ko00000,ko02000	5.A.3.8	-	-	Molybdopterin,Molydop_binding
k59_1018483_1	395494.Galf_2238	6.7e-35	137.0	COG3614@1|root,COG3829@1|root,COG5002@1|root,COG3614@2|Bacteria,COG3829@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2WGSV@28216|Betaproteobacteria	28216|Betaproteobacteria	T	CHASE	-	-	-	-	-	-	-	-	-	-	-	-	CHASE
k59_1134729_1	1304883.KI912532_gene2690	1.77e-70	216.0	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,2VR65@28216|Betaproteobacteria,2KW50@206389|Rhodocyclales	206389|Rhodocyclales	S	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
k59_1839742_1	243159.AFE_1494	5.52e-48	166.0	COG0614@1|root,COG0614@2|Bacteria,1NVK4@1224|Proteobacteria,1RRND@1236|Gammaproteobacteria,2NE40@225057|Acidithiobacillales	225057|Acidithiobacillales	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
k59_191464_1	272562.CA_C2523	1.71e-94	289.0	COG1215@1|root,COG1215@2|Bacteria,1TR2P@1239|Firmicutes,248SW@186801|Clostridia	186801|Clostridia	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18,Glyco_tranf_2_3,Glycos_transf_2,Polysacc_deac_1
k59_1660799_1	1537917.JU82_00850	2.59e-117	352.0	COG0074@1|root,COG0372@1|root,COG0074@2|Bacteria,COG0372@2|Bacteria,1MUGA@1224|Proteobacteria,42NI0@68525|delta/epsilon subdivisions,2YNKI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	ATP citrate synthase	-	-	2.3.3.8	ko:K15230	ko00020,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00720,map01100,map01110,map01120,map01130,map01200	M00173	R00352	RC00004,RC00067	ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt,Ligase_CoA
k59_665892_1	1165841.SULAR_10619	1.36e-124	368.0	COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,42M8Q@68525|delta/epsilon subdivisions,2YMSH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome c oxidase accessory protein	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
k59_72839_1	1249480.B649_08850	1.05e-107	325.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,42MPH@68525|delta/epsilon subdivisions,2YMZ9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	N-acetylmuramoyl-L-alanine amidase	amiA	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
k59_1546118_2	1304883.KI912532_gene1873	4.99e-27	99.8	COG2906@1|root,COG2906@2|Bacteria,1NGGY@1224|Proteobacteria,2VWVZ@28216|Betaproteobacteria,2KX62@206389|Rhodocyclales	206389|Rhodocyclales	P	BFD-like [2Fe-2S] binding domain	bfd	-	-	ko:K02192	-	-	-	-	ko00000	-	-	-	Fer2_BFD
k59_1777689_1	857087.Metme_2402	6.52e-62	213.0	COG2203@1|root,COG3437@1|root,COG5001@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XG5E@135618|Methylococcales	135618|Methylococcales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_4
k59_1718898_1	387093.SUN_1840	9.93e-55	186.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,42NYD@68525|delta/epsilon subdivisions,2YNI5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Permease, YjgP YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_1428322_1	709032.Sulku_0295	4.42e-45	146.0	29H9G@1|root,30470@2|Bacteria,1QR1D@1224|Proteobacteria,42TWI@68525|delta/epsilon subdivisions,2YPSP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_957866_1	1537917.JU82_11775	2.34e-112	328.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,42RGS@68525|delta/epsilon subdivisions,2YNY5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_N
k59_957866_2	1249480.B649_02530	6.67e-11	57.8	COG1551@1|root,COG1551@2|Bacteria,1Q4KC@1224|Proteobacteria,42W0C@68525|delta/epsilon subdivisions,2YQ7K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the CsrA family	csrA	-	-	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03019	-	-	-	CsrA
k59_72863_1	1165841.SULAR_04132	1.36e-90	275.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,42NJE@68525|delta/epsilon subdivisions,2YM8V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
k59_251822_1	1249480.B649_08055	1.14e-116	344.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2YMTZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iIT341.HP0623	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_1601484_1	1304883.KI912532_gene329	6.73e-127	369.0	COG3825@1|root,COG3825@2|Bacteria,1MUAJ@1224|Proteobacteria,2VJ99@28216|Betaproteobacteria,2KUDU@206389|Rhodocyclales	206389|Rhodocyclales	S	Von Willebrand factor A	-	-	-	ko:K09989	-	-	-	-	ko00000	-	-	-	VWA_CoxE
k59_840159_1	1156937.MFUM_970081	2.83e-66	224.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,46SVA@74201|Verrucomicrobia,37FY0@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
k59_840163_1	159087.Daro_2859	2.26e-58	200.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,2VJ0G@28216|Betaproteobacteria,2KVN8@206389|Rhodocyclales	206389|Rhodocyclales	C	Dehydrogenase E1 component	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
k59_840163_2	85643.Tmz1t_2545	4.04e-50	170.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,2VIJF@28216|Betaproteobacteria,2KVDB@206389|Rhodocyclales	206389|Rhodocyclales	H	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
k59_665948_1	709032.Sulku_0119	8.79e-118	341.0	COG0739@1|root,COG0739@2|Bacteria,1MY2X@1224|Proteobacteria,42U06@68525|delta/epsilon subdivisions,2YP2U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_1018575_1	1249480.B649_04345	3.13e-121	350.0	COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,42PC4@68525|delta/epsilon subdivisions,2YP8E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	radicals which are normally produced within the cells and which are toxic to biological systems	sodB	GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
k59_1485164_1	1300005.R9RGE6_9CAUD	8.66e-73	235.0	4QB5I@10239|Viruses,4QWYV@35237|dsDNA viruses  no RNA stage,4QTTK@28883|Caudovirales	28883|Caudovirales	S	ATP-dependent DNA helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1546183_3	929558.SMGD1_1895	4.5e-05	45.1	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,42M9S@68525|delta/epsilon subdivisions,2YMAH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the ClpA ClpB family	clpB	-	-	ko:K03694,ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_1018597_1	1249480.B649_09380	3.04e-61	200.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,42N2T@68525|delta/epsilon subdivisions,2YNID@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	acid membrane antigen A	amaA	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k59_1253065_1	159087.Daro_4016	8.96e-52	172.0	2BCNC@1|root,3268I@2|Bacteria,1NETW@1224|Proteobacteria,2VVQW@28216|Betaproteobacteria,2KZIB@206389|Rhodocyclales	206389|Rhodocyclales	S	Phosphoribosyl-dephospho-CoA transferase MdcG	-	-	2.7.7.66	ko:K13934	-	-	R10706	-	ko00000,ko01000	-	-	-	MdcG
k59_191553_1	709032.Sulku_1739	3.23e-128	392.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2YRKW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0474 Cation transport ATPase	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
k59_897637_1	760117.JN27_23380	1.63e-110	322.0	COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,2VIZW@28216|Betaproteobacteria,4731K@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	modB	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
k59_251862_1	1168034.FH5T_14410	1.27e-108	324.0	COG0621@1|root,COG0621@2|Bacteria,4NZXZ@976|Bacteroidetes,2FX31@200643|Bacteroidia	976|Bacteroidetes	J	TRAM domain	-	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
k59_1366753_1	387093.SUN_1222	2.99e-29	107.0	COG1246@1|root,COG1246@2|Bacteria,1RHT7@1224|Proteobacteria,42SGE@68525|delta/epsilon subdivisions,2YPNW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	acetyltransferase	-	-	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
k59_1366753_2	387093.SUN_1221	4.28e-39	136.0	2AJKY@1|root,31A84@2|Bacteria,1Q53J@1224|Proteobacteria,430GT@68525|delta/epsilon subdivisions,2YRZ0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1366753_3	1165841.SULAR_04417	2.13e-14	72.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,42M1S@68525|delta/epsilon subdivisions,2YMEF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	penicillin-binding protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
k59_308455_2	159087.Daro_3736	6.91e-39	135.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,2VQTQ@28216|Betaproteobacteria,2KW1F@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
k59_717279_2	1249480.B649_01685	4.39e-45	153.0	COG1639@1|root,COG1639@2|Bacteria,1Q1C5@1224|Proteobacteria,42T98@68525|delta/epsilon subdivisions,2YPNT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_367480_1	387093.SUN_0210	9.61e-13	66.6	COG2010@1|root,COG2857@1|root,COG2010@2|Bacteria,COG2857@2|Bacteria,1PX4N@1224|Proteobacteria,42MFF@68525|delta/epsilon subdivisions,2YMBA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	ubiquinol cytochrome c oxidoreductase, cytochrome c1	petC	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	iIT341.HP1538	Cytochrom_C,Cytochrom_C1
k59_367480_2	387093.SUN_0209	2.07e-70	223.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,42MD6@68525|delta/epsilon subdivisions,2YMXT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petB	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
k59_1253094_1	749222.Nitsa_1691	2.14e-24	94.7	2AK1S@1|root,31ARD@2|Bacteria,1Q602@1224|Proteobacteria,43A9Q@68525|delta/epsilon subdivisions,2YQSC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1253094_2	1442598.JABW01000003_gene61	2.75e-58	184.0	COG1854@1|root,COG1854@2|Bacteria,1MWQF@1224|Proteobacteria,42QP7@68525|delta/epsilon subdivisions,2YNWJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)	luxS	-	4.4.1.21	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	M00609	R01291	RC00069,RC01929	ko00000,ko00001,ko00002,ko01000	-	-	-	LuxS
k59_427122_1	709032.Sulku_1394	2.27e-100	317.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2YMQV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_488989_1	1121374.KB891576_gene691	1.12e-26	103.0	COG0782@1|root,COG0782@2|Bacteria,1RAP0@1224|Proteobacteria,1S40Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length	greB	-	-	ko:K04760	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
k59_1615415_1	1239962.C943_03417	7.51e-07	57.0	COG0642@1|root,COG0784@1|root,COG1807@1|root,COG0784@2|Bacteria,COG1807@2|Bacteria,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,HisKA_7TM,Hpt,Response_reg,TPR_12
k59_504448_1	1185653.A1A1_06357	5.79e-11	64.7	COG1120@1|root,COG1865@1|root,COG1120@2|Bacteria,COG1865@2|Bacteria,1TP2Q@1239|Firmicutes,4HA28@91061|Bacilli,26E82@186818|Planococcaceae	91061|Bacilli	HP	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components	yvrA	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran,CbiZ
k59_504448_2	1165841.SULAR_05603	1.2e-29	115.0	COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,42M78@68525|delta/epsilon subdivisions,2YMR1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
k59_566757_1	1249480.B649_05760	1.05e-176	523.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YM96@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	cmeF	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_852763_1	1537917.JU82_00700	7.66e-68	216.0	COG2038@1|root,COG2038@2|Bacteria,1NZFH@1224|Proteobacteria,42NRQ@68525|delta/epsilon subdivisions,2YNQ9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	phosphoribosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DBI_PRT
k59_910775_1	207954.MED92_18233	4.8e-17	85.9	COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,1RPV3@1236|Gammaproteobacteria,1XISX@135619|Oceanospirillales	135619|Oceanospirillales	NU	Tfp pilus assembly protein, tip-associated adhesin PilY1	-	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC
k59_1151157_1	985762.SAGN_09532	2.55e-09	58.9	COG0745@1|root,COG0745@2|Bacteria,1TPU2@1239|Firmicutes,4HD93@91061|Bacilli,4GZ06@90964|Staphylococcaceae	91061|Bacilli	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K02483,ko:K11521	ko02020,map02020	M00465	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_1151157_2	1122212.AULO01000010_gene328	6.17e-06	50.4	COG2931@1|root,COG5276@1|root,COG2931@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,FG-GAP,HemolysinCabind,PPC,Peptidase_S8,TSP_3
k59_1563719_1	926692.AZYG01000085_gene856	3.49e-54	185.0	COG2801@1|root,COG2801@2|Bacteria,1TU21@1239|Firmicutes,249HN@186801|Clostridia,3WA8E@53433|Halanaerobiales	186801|Clostridia	L	Integrase catalytic region	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
k59_566776_1	1123073.KB899245_gene151	5.9e-16	80.9	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,1RQ6B@1236|Gammaproteobacteria,1X47J@135614|Xanthomonadales	135614|Xanthomonadales	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_1088886_1	1276756.AUEX01000035_gene2220	5.24e-123	366.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,2VGZ9@28216|Betaproteobacteria,4A9WD@80864|Comamonadaceae	28216|Betaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
k59_440945_1	1123518.ARWI01000001_gene2400	4.31e-16	78.2	COG3079@1|root,COG3079@2|Bacteria,1N7W0@1224|Proteobacteria,1SCPW@1236|Gammaproteobacteria,4619U@72273|Thiotrichales	72273|Thiotrichales	S	Belongs to the UPF0149 family	-	-	-	ko:K09895	-	-	-	-	ko00000	-	-	-	UPF0149
k59_440945_2	90813.JQMT01000001_gene1354	5.89e-26	106.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RN0W@1236|Gammaproteobacteria,45ZRX@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the peptidase M24B family	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
k59_974041_1	1123392.AQWL01000003_gene141	2.63e-92	281.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,2VJGA@28216|Betaproteobacteria	28216|Betaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	ko:K21834	-	-	-	-	ko00000	-	-	-	CCG,DUF3483,Fer4_8
k59_1733036_1	1537917.JU82_10810	8.11e-85	263.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,42NGG@68525|delta/epsilon subdivisions,2YN35@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Nucleotidyltransferase DNA polymerase involved in DNA repair	dinP	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
k59_910796_1	1232437.KL662050_gene5382	2.69e-71	226.0	COG2267@1|root,COG2267@2|Bacteria,1PWD1@1224|Proteobacteria,43919@68525|delta/epsilon subdivisions,2X46M@28221|Deltaproteobacteria,2MPCU@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
k59_318661_2	709032.Sulku_1503	1.59e-48	155.0	2A433@1|root,30SN2@2|Bacteria,1PBWY@1224|Proteobacteria,42VT4@68525|delta/epsilon subdivisions,2YQB2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1674486_1	159087.Daro_2456	4.94e-12	63.2	COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,2VKIN@28216|Betaproteobacteria,2KW8D@206389|Rhodocyclales	206389|Rhodocyclales	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
k59_1674486_2	159087.Daro_2455	3.32e-53	179.0	COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,2VITB@28216|Betaproteobacteria,2KUDH@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_621368_1	644107.SL1157_3321	5.32e-07	52.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2U5A1@28211|Alphaproteobacteria,4NB9P@97050|Ruegeria	28211|Alphaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_440993_1	1537917.JU82_03910	1.18e-100	303.0	COG0507@1|root,COG0507@2|Bacteria,1QCFP@1224|Proteobacteria,42NH5@68525|delta/epsilon subdivisions,2YMK5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member	-	-	-	-	-	-	-	-	-	-	-	-	Herpes_Helicase,PIF1
k59_1733077_1	159087.Daro_4161	4.24e-46	155.0	COG0647@1|root,COG0647@2|Bacteria,1QGX4@1224|Proteobacteria,2VKI3@28216|Betaproteobacteria,2KW0E@206389|Rhodocyclales	206389|Rhodocyclales	G	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K02566	-	-	-	-	ko00000	-	-	-	Hydrolase_6,Hydrolase_like
k59_1088955_2	1123325.JHUV01000008_gene655	3.18e-180	535.0	COG3696@1|root,COG3696@2|Bacteria	2|Bacteria	P	silver ion transport	czcA	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
k59_1446410_1	1249480.B649_06135	2.11e-78	240.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,42MPA@68525|delta/epsilon subdivisions,2YMKT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
k59_1791237_2	1249480.B649_07925	3.49e-20	87.0	COG1686@1|root,COG1686@2|Bacteria,1MWZA@1224|Proteobacteria,43AWC@68525|delta/epsilon subdivisions,2YT3V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
k59_1791247_1	395494.Galf_0971	4.01e-68	215.0	COG3547@1|root,COG3547@2|Bacteria,1P502@1224|Proteobacteria,2W9QQ@28216|Betaproteobacteria,44WNJ@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_207686_1	748247.AZKH_0561	3.91e-163	475.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,2VJUZ@28216|Betaproteobacteria,2KVFW@206389|Rhodocyclales	206389|Rhodocyclales	EQ	Hydantoinase/oxoprolinase N-terminal region	acxA	-	6.4.1.6	ko:K10855	-	-	-	-	ko00000,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
k59_796154_1	1249480.B649_07335	3.13e-137	400.0	COG3400@1|root,COG3400@2|Bacteria,1N5T1@1224|Proteobacteria,42M0B@68525|delta/epsilon subdivisions,2YMCG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	domain protein	-	-	-	ko:K09944	-	-	-	-	ko00000	-	-	-	TrkA_C
k59_727734_1	709032.Sulku_2321	1.83e-154	436.0	COG4121@1|root,COG4121@2|Bacteria,1Q8T8@1224|Proteobacteria,42RAP@68525|delta/epsilon subdivisions,2YP3B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_30
k59_504592_1	1537917.JU82_07435	2.45e-80	247.0	COG0859@1|root,COG0859@2|Bacteria,1N5A1@1224|Proteobacteria,42S5Z@68525|delta/epsilon subdivisions,2YP6I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG0859 ADP-heptose LPS heptosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
k59_621424_1	929558.SMGD1_0383	2.28e-54	177.0	COG1413@1|root,COG1413@2|Bacteria,1RIZR@1224|Proteobacteria	1224|Proteobacteria	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
k59_1791262_1	159087.Daro_4201	9.06e-138	404.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,2VHIA@28216|Betaproteobacteria,2KUBX@206389|Rhodocyclales	206389|Rhodocyclales	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
k59_1617720_1	1121035.AUCH01000007_gene582	1.81e-124	364.0	COG2224@1|root,COG2224@2|Bacteria,1MWIF@1224|Proteobacteria,2VHWS@28216|Betaproteobacteria,2KUZG@206389|Rhodocyclales	206389|Rhodocyclales	C	Isocitrate lyase	aceA	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	ICL
k59_1383555_1	395494.Galf_2662	4.27e-124	360.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,2VHBP@28216|Betaproteobacteria,44UYZ@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dusB	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
k59_210106_1	62928.azo1392	1.58e-68	215.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,2VH6Y@28216|Betaproteobacteria,2KUHB@206389|Rhodocyclales	206389|Rhodocyclales	P	Phosphate transport system permease	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
k59_1320665_1	1304883.KI912532_gene2566	1.22e-108	325.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,2VHR6@28216|Betaproteobacteria,2KUMA@206389|Rhodocyclales	206389|Rhodocyclales	E	Threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_synth_N
k59_1859767_1	317025.Tcr_0709	2.7e-59	194.0	COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,1RM7R@1236|Gammaproteobacteria,460BA@72273|Thiotrichales	72273|Thiotrichales	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
k59_1859767_2	1234595.C725_2139	1.07e-23	97.8	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,2TR60@28211|Alphaproteobacteria,4BPVW@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
k59_1383568_1	1537917.JU82_04590	1.07e-82	250.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,42NEA@68525|delta/epsilon subdivisions,2YN5P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
k59_1383568_2	1537917.JU82_04595	5.68e-32	119.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,42M3E@68525|delta/epsilon subdivisions,2YMQZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
k59_1617734_1	1298593.TOL_3531	8.54e-94	284.0	COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,1RQ2N@1236|Gammaproteobacteria,1XHTS@135619|Oceanospirillales	135619|Oceanospirillales	E	Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine	metX	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
k59_1206537_1	1165841.SULAR_07545	2.61e-81	250.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,42M7V@68525|delta/epsilon subdivisions,2YMKI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
k59_1566223_1	1121129.KB903359_gene2286	0.00018	49.3	COG0845@1|root,COG0845@2|Bacteria,4NFT4@976|Bacteroidetes,2FN2G@200643|Bacteroidia,22W7Z@171551|Porphyromonadaceae	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
k59_623535_1	387093.SUN_0562	1.57e-64	206.0	COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,42M4G@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005,ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_D23
k59_623535_2	387093.SUN_0564	5.04e-10	58.2	COG0693@1|root,COG0693@2|Bacteria,1N7T2@1224|Proteobacteria,42RGX@68525|delta/epsilon subdivisions,2YPA8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	TIGRFAM DJ-1 family protein	thiJ	-	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
k59_1273263_1	1249480.B649_09455	9.33e-102	306.0	COG0446@1|root,COG0446@2|Bacteria,1QA17@1224|Proteobacteria,42P5E@68525|delta/epsilon subdivisions,2YN01@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Fad-dependent pyridine nucleotide-disulfide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_210171_1	159087.Daro_0485	1.17e-141	418.0	COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,2VH9I@28216|Betaproteobacteria,2KUQJ@206389|Rhodocyclales	206389|Rhodocyclales	P	Transport of potassium into the cell	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
k59_506695_1	160492.XF_2638	1.11e-11	62.8	COG0250@1|root,COG0250@2|Bacteria,1MU14@1224|Proteobacteria,1RMW0@1236|Gammaproteobacteria,1X36J@135614|Xanthomonadales	135614|Xanthomonadales	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
k59_506695_2	90813.JQMT01000001_gene201	1.89e-26	102.0	COG0690@1|root,COG0690@2|Bacteria,1RDI9@1224|Proteobacteria,1S3PA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
k59_1859846_1	1165841.SULAR_07340	1.76e-09	57.4	COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,42M6S@68525|delta/epsilon subdivisions,2YMJG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
k59_1859846_2	1165841.SULAR_07335	1.98e-145	418.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,42MW6@68525|delta/epsilon subdivisions,2YN0V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Potassium channel protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
k59_686176_2	1537917.JU82_10785	1.13e-07	50.4	COG1826@1|root,COG1826@2|Bacteria,1NGDP@1224|Proteobacteria,42VNG@68525|delta/epsilon subdivisions,2YQ9F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
k59_686189_1	709032.Sulku_0642	2.26e-137	420.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,42MWW@68525|delta/epsilon subdivisions,2YMMH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_210232_1	709032.Sulku_1874	4.37e-72	233.0	COG3746@1|root,COG3746@2|Bacteria,1MY3M@1224|Proteobacteria,42NVN@68525|delta/epsilon subdivisions,2YMH8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_798908_2	1537917.JU82_02880	5.18e-94	280.0	COG2836@1|root,COG2836@2|Bacteria,1QZ1V@1224|Proteobacteria,430HB@68525|delta/epsilon subdivisions,2YRZU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	DsbD_2
k59_154554_1	1249480.B649_03465	1.38e-85	271.0	COG1256@1|root,COG1749@1|root,COG1256@2|Bacteria,COG1749@2|Bacteria,1MV2M@1224|Proteobacteria,42PBN@68525|delta/epsilon subdivisions,2YMGR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar hook-associated protein	flgK	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k59_1273364_1	709032.Sulku_0800	3.47e-35	129.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,42PGM@68525|delta/epsilon subdivisions,2YTQ3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
k59_1273364_2	1249480.B649_08095	2.72e-46	152.0	COG1846@1|root,COG1846@2|Bacteria,1NKV4@1224|Proteobacteria,42RNI@68525|delta/epsilon subdivisions	1224|Proteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
k59_1091420_1	709032.Sulku_1858	5.8e-13	66.2	COG2928@1|root,COG2928@2|Bacteria,1PKH9@1224|Proteobacteria,42XVN@68525|delta/epsilon subdivisions,2YQSF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
k59_1091420_2	1249480.B649_08895	5.48e-63	209.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,42MUY@68525|delta/epsilon subdivisions,2YMZF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	PFAM peptidase M3A and M3B thimet oligopeptidase F	prlC	-	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
k59_1383723_1	1249480.B649_06155	1.51e-78	259.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YN16@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	GGDEF EAL family protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,NIT,PAS_3,PAS_9
k59_569604_1	387093.SUN_0633	5.27e-195	573.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YMMN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1206694_1	653733.Selin_1972	1.52e-98	311.0	COG1449@1|root,COG1449@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 57 family	amyA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.4.1.25	ko:K22451	ko00500,map00500	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH57	-	DUF1925,DUF1926,Glyco_hydro_57
k59_443080_1	709032.Sulku_0987	2.43e-102	305.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,42M8G@68525|delta/epsilon subdivisions,2YME5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
k59_443080_2	1537917.JU82_01125	2.82e-51	162.0	29ZJG@1|root,30MJQ@2|Bacteria,1Q1QI@1224|Proteobacteria,42U6T@68525|delta/epsilon subdivisions,2YPWC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1499752_1	292415.Tbd_0652	1.5e-86	281.0	COG0508@1|root,COG1249@1|root,COG0508@2|Bacteria,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VI6G@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Dehydrogenase	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding,Pyr_redox_2,Pyr_redox_dim
k59_912942_1	709032.Sulku_1007	2.51e-188	537.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,42M81@68525|delta/epsilon subdivisions,2YMTF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_267376_1	1537917.JU82_05260	8.48e-106	316.0	COG2199@1|root,COG3706@2|Bacteria,1MWHH@1224|Proteobacteria,42RQ2@68525|delta/epsilon subdivisions,2YP69@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG2199 FOG GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,GGDEF
k59_382295_1	412965.COSY_0346	5.01e-13	67.8	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,1RMDD@1236|Gammaproteobacteria,1J4HD@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Heat shock 70 kDa protein	dnaK	GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
k59_382295_2	1123517.JOMR01000001_gene1298	2.62e-54	177.0	COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,1S5W5@1236|Gammaproteobacteria,460QM@72273|Thiotrichales	72273|Thiotrichales	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
k59_29517_1	709032.Sulku_0655	2.97e-156	447.0	COG0245@1|root,COG1211@1|root,COG0245@2|Bacteria,COG1211@2|Bacteria,1MVHA@1224|Proteobacteria,42MJ6@68525|delta/epsilon subdivisions,2YMEK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF)	ispDF	-	2.7.7.60,4.6.1.12	ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
k59_210373_1	709032.Sulku_1497	2.1e-120	357.0	COG2710@1|root,COG2710@2|Bacteria,1MWQ4@1224|Proteobacteria,42MNG@68525|delta/epsilon subdivisions,2YNM4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation	-	-	1.18.6.1	ko:K02591	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF3364,Oxidored_nitro
k59_623731_1	1538295.JY96_12240	4.33e-81	242.0	COG1513@1|root,COG1513@2|Bacteria,1R9X0@1224|Proteobacteria,2VQ5F@28216|Betaproteobacteria,1KKRQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide	cynS	-	4.2.1.104	ko:K01725	ko00910,map00910	-	R03546,R10079	RC00952	ko00000,ko00001,ko01000	-	-	-	Cyanate_lyase
k59_623731_2	887898.HMPREF0551_0556	1.87e-73	223.0	COG1765@1|root,COG1765@2|Bacteria,1MWPR@1224|Proteobacteria,2VM4K@28216|Betaproteobacteria,1K8BS@119060|Burkholderiaceae	28216|Betaproteobacteria	O	PFAM OsmC family protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
k59_1320908_1	1304888.ATWF01000001_gene562	9.46e-38	144.0	COG2199@1|root,COG2202@1|root,COG3452@1|root,COG3829@1|root,COG2202@2|Bacteria,COG3452@2|Bacteria,COG3706@2|Bacteria,COG3829@2|Bacteria,2GGBB@200930|Deferribacteres	200930|Deferribacteres	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_3
k59_569689_2	583345.Mmol_0539	1.69e-91	271.0	COG2836@1|root,COG2836@2|Bacteria,1PN2Q@1224|Proteobacteria,2VNU4@28216|Betaproteobacteria,2KMZ8@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
k59_1153950_2	472759.Nhal_3166	2.06e-48	158.0	arCOG08935@1|root,32Z08@2|Bacteria,1R3HB@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1091563_1	1123514.KB905899_gene1647	1.03e-37	140.0	COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,1RM8H@1236|Gammaproteobacteria,460N2@72273|Thiotrichales	72273|Thiotrichales	S	Permease YjgP YjgQ	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_210415_1	709032.Sulku_2546	0.0	956.0	COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,42P71@68525|delta/epsilon subdivisions,2YNAA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Phospholipid glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5,Acyltransferase
k59_1566491_1	1415778.JQMM01000001_gene1018	6.76e-25	101.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,1RMKP@1236|Gammaproteobacteria,1J4X5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0031119,GO:0034337,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
k59_1566491_2	1168067.JAGP01000001_gene973	2.57e-20	86.3	COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,1S9AF@1236|Gammaproteobacteria,46168@72273|Thiotrichales	72273|Thiotrichales	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
k59_854805_1	709032.Sulku_1553	7.39e-151	430.0	COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,42VWM@68525|delta/epsilon subdivisions,2YQKK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COG0714 MoxR-like	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
k59_1793436_1	159087.Daro_0561	1.6e-118	352.0	COG0840@1|root,COG0840@2|Bacteria,1NJXF@1224|Proteobacteria,2VM8I@28216|Betaproteobacteria,2KUYK@206389|Rhodocyclales	206389|Rhodocyclales	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal
k59_1639055_2	1537917.JU82_08420	5.5e-38	139.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2YMA3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_1342417_1	522373.Smlt1089	2.34e-45	155.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,1RN8G@1236|Gammaproteobacteria,1X3Y4@135614|Xanthomonadales	135614|Xanthomonadales	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_1342417_2	95619.PM1_0226625	1.84e-48	161.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,1RNPM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	yggS	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
k59_524426_2	159087.Daro_3406	2.32e-43	152.0	COG0457@1|root,COG0457@2|Bacteria,1RKBG@1224|Proteobacteria,2VQFW@28216|Betaproteobacteria,2KWI5@206389|Rhodocyclales	206389|Rhodocyclales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19
k59_1695220_2	709032.Sulku_1991	6.93e-61	194.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,42M2I@68525|delta/epsilon subdivisions,2YMER@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
k59_1639102_1	1336235.JAEG01000004_gene3752	2.93e-68	214.0	296ZZ@1|root,2ZU8H@2|Bacteria,1RED2@1224|Proteobacteria,2U6CK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1342469_1	709032.Sulku_0263	3.16e-35	129.0	COG0840@1|root,COG0840@2|Bacteria,1R5W9@1224|Proteobacteria,42SRV@68525|delta/epsilon subdivisions,2YR7J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	CZB,MCPsignal
k59_1110221_1	1123354.AUDR01000015_gene246	6.54e-66	206.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,2VIUA@28216|Betaproteobacteria,1KRKY@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
k59_818953_1	1249480.B649_00720	4.67e-92	289.0	COG1345@1|root,COG1345@2|Bacteria,1MUVP@1224|Proteobacteria,42MHW@68525|delta/epsilon subdivisions,2YNJG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	fliD	GO:0001539,GO:0005575,GO:0005576,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_IN,FliD_C,FliD_N
k59_1811230_1	1304883.KI912532_gene2362	2.6e-126	380.0	COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,2VJ9A@28216|Betaproteobacteria,2KV3Z@206389|Rhodocyclales	206389|Rhodocyclales	C	UPF0313 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
k59_1639148_1	159087.Daro_2944	2.46e-126	365.0	COG0175@1|root,COG0175@2|Bacteria,1MUCZ@1224|Proteobacteria,2VJH9@28216|Betaproteobacteria,2KUTB@206389|Rhodocyclales	206389|Rhodocyclales	H	COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase and related enzymes	cysD	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
k59_1639154_1	357804.Ping_0949	2.18e-37	145.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2QIXR@267894|Psychromonadaceae	1236|Gammaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,MASE3,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
k59_643790_2	709032.Sulku_1165	2.78e-102	297.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,42MN8@68525|delta/epsilon subdivisions,2YPGX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Belongs to the Fur family	fur	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
k59_1520243_1	1304883.KI912532_gene2151	2.36e-48	169.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VIP3@28216|Betaproteobacteria,2KUJV@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k59_401478_1	1165841.SULAR_05298	7.23e-28	112.0	COG1450@1|root,COG1450@2|Bacteria,1MVNC@1224|Proteobacteria,43BJ2@68525|delta/epsilon subdivisions,2YN49@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Type II and III secretion system protein	ctsD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	STN,Secretin,Secretin_N_2
k59_1756066_1	395494.Galf_1246	4.74e-09	57.4	COG0517@1|root,COG2199@1|root,COG0517@2|Bacteria,COG2199@2|Bacteria,1RGCV@1224|Proteobacteria,2W303@28216|Betaproteobacteria	28216|Betaproteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4
k59_173977_1	1249480.B649_03590	1.1e-187	536.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MHP@68525|delta/epsilon subdivisions,2YN92@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k59_173977_2	709032.Sulku_1829	6.44e-124	355.0	COG0847@1|root,COG0847@2|Bacteria,1P0GY@1224|Proteobacteria,42RBT@68525|delta/epsilon subdivisions,2YNWW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	dna polymerase iii	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_1342575_1	395494.Galf_0072	9.03e-83	266.0	COG0840@1|root,COG0840@2|Bacteria,1MWU2@1224|Proteobacteria,2VNA8@28216|Betaproteobacteria,44WCH@713636|Nitrosomonadales	28216|Betaproteobacteria	NT	SMART chemotaxis sensory transducer	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal
k59_747239_1	1163617.SCD_n00436	2.4e-06	49.3	COG3213@1|root,COG3213@2|Bacteria,1MUJK@1224|Proteobacteria,2VJ75@28216|Betaproteobacteria	28216|Betaproteobacteria	P	PFAM NnrS family protein	-	-	-	ko:K07234	-	-	-	-	ko00000	-	-	-	NnrS
k59_747239_2	292415.Tbd_2175	1.77e-35	122.0	COG4309@1|root,COG4309@2|Bacteria,1N4MS@1224|Proteobacteria,2VU7H@28216|Betaproteobacteria,1KT9I@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Uncharacterized conserved protein (DUF2249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2249
k59_401526_1	709032.Sulku_0270	7.68e-107	330.0	COG1034@1|root,COG1034@2|Bacteria,1RCFT@1224|Proteobacteria,42NK4@68525|delta/epsilon subdivisions,2YNI6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G)	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4_10,Molybdopterin,NADH-G_4Fe-4S_3
k59_229823_1	583345.Mmol_0326	1.7e-86	259.0	COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,2VK46@28216|Betaproteobacteria,2KM0P@206350|Nitrosomonadales	206350|Nitrosomonadales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	1.10.2.2	ko:K00411	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,UCR_Fe-S_N
k59_342499_1	1249480.B649_11315	1.19e-122	359.0	COG0577@1|root,COG0577@2|Bacteria,1QT4V@1224|Proteobacteria,42P7K@68525|delta/epsilon subdivisions,2YNGD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	ABC transporter permease	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
k59_1227825_1	929558.SMGD1_0680	6.25e-91	293.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,43AX5@68525|delta/epsilon subdivisions,2YT40@29547|Epsilonproteobacteria	1224|Proteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_9,Response_reg
k59_464392_1	709032.Sulku_2488	7.7e-47	153.0	2B1KW@1|root,31U2C@2|Bacteria,1QRVW@1224|Proteobacteria,42WG1@68525|delta/epsilon subdivisions,2YQCP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_49708_1	1537917.JU82_11505	3.33e-93	278.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,42MV7@68525|delta/epsilon subdivisions,2YMFH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
k59_1758372_1	243159.AFE_1691	3.02e-104	313.0	COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,1RRMX@1236|Gammaproteobacteria,2NC83@225057|Acidithiobacillales	225057|Acidithiobacillales	H	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site	cbbL	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
k59_749365_1	1249480.B649_00135	2.18e-73	222.0	2AIZZ@1|root,319I0@2|Bacteria,1Q2U7@1224|Proteobacteria,42W9A@68525|delta/epsilon subdivisions,2YQB5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1404921_1	709032.Sulku_2534	1.62e-80	266.0	COG3164@1|root,COG3164@2|Bacteria,1QUYX@1224|Proteobacteria,43CES@68525|delta/epsilon subdivisions,2YTC9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
k59_1641479_1	1165841.SULAR_00120	2.25e-269	770.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2YMA1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
k59_874011_1	159087.Daro_1394	4.27e-61	190.0	COG0760@1|root,COG0760@2|Bacteria,1QUCX@1224|Proteobacteria,2WGPH@28216|Betaproteobacteria,2KWSM@206389|Rhodocyclales	206389|Rhodocyclales	O	NifZ domain	-	-	-	ko:K02597	-	-	-	-	ko00000	-	-	-	NifZ
k59_874011_2	159087.Daro_1395	5.23e-61	188.0	2E67S@1|root,330W8@2|Bacteria,1NA3E@1224|Proteobacteria,2VX71@28216|Betaproteobacteria,2KX7Q@206389|Rhodocyclales	206389|Rhodocyclales	S	May protect the nitrogenase Fe-Mo protein from oxidative damage	nifW	-	-	ko:K02595	-	-	-	-	ko00000	-	-	-	NifW
k59_1758400_1	709032.Sulku_2335	1e-44	154.0	COG3907@1|root,COG3907@2|Bacteria,1MY7B@1224|Proteobacteria,42RAC@68525|delta/epsilon subdivisions,2YQ1I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COGs COG3907 PAP2 (acid phosphatase) superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
k59_1758400_2	572480.Arnit_3134	7.96e-160	467.0	COG2194@1|root,COG2194@2|Bacteria,1MWS7@1224|Proteobacteria,42MI1@68525|delta/epsilon subdivisions,2YMPQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Sulfatase	eptA	-	2.7.8.43	ko:K03760	ko01503,map01503	M00722	R11555,R11556,R11557	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DUF1705,Sulfatase
k59_1227900_1	709032.Sulku_1274	3.31e-54	181.0	COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,42N4P@68525|delta/epsilon subdivisions,2YMDF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
k59_1227900_2	749222.Nitsa_1009	9.5e-29	110.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42Q5V@68525|delta/epsilon subdivisions,2YND0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
k59_1344787_1	1304883.KI912532_gene2631	9.3e-89	283.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,2VHR1@28216|Betaproteobacteria,2KUJG@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k59_1112673_1	1165841.SULAR_01350	5.72e-105	330.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2YMQV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_1813087_1	709032.Sulku_1141	4.15e-104	307.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,42MY7@68525|delta/epsilon subdivisions,2YP09@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the NadC ModD family	modD	-	-	ko:K03813	-	-	-	-	ko00000,ko01000	-	-	-	QRPTase_C,QRPTase_N
k59_229968_1	709032.Sulku_2230	1.4e-30	112.0	COG4969@1|root,COG4969@2|Bacteria,1QZMY@1224|Proteobacteria,42WPI@68525|delta/epsilon subdivisions,2YQFF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
k59_229968_2	709032.Sulku_2231	1.85e-50	162.0	COG4969@1|root,COG4969@2|Bacteria,1QZMZ@1224|Proteobacteria,42U5N@68525|delta/epsilon subdivisions,2YPXN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
k59_526848_1	1249480.B649_06135	6.25e-97	290.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,42MPA@68525|delta/epsilon subdivisions,2YMKT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
k59_821409_1	1280946.HY29_04045	5.52e-38	148.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TXUJ@28211|Alphaproteobacteria,43X61@69657|Hyphomonadaceae	28211|Alphaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,MASE1,PAS_3,Response_reg
k59_1522069_1	563040.Saut_0386	7.05e-34	134.0	COG0784@1|root,COG2198@1|root,COG3287@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG3287@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,43BU6@68525|delta/epsilon subdivisions,2YTEC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Two-component sensor histidine kinase response regulator	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C,HATPase_c,HisKA,Response_reg
k59_874194_1	326298.Suden_0622	1.29e-116	347.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,42M14@68525|delta/epsilon subdivisions,2YMWB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Biotin carboxylase	pycA	-	6.3.4.14,6.4.1.1,6.4.1.2	ko:K01959,ko:K01961	ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko01230,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212,map01230	M00082,M00173,M00376,M00620	R00344,R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
k59_1697905_1	387093.SUN_0633	2.32e-86	281.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YMMN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_526947_1	159087.Daro_0535	8.69e-62	192.0	COG2606@1|root,COG2606@2|Bacteria,1RGX5@1224|Proteobacteria,2VQAY@28216|Betaproteobacteria,2KW2N@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
k59_526947_3	742159.HMPREF0004_4968	3.93e-34	125.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,2VIHD@28216|Betaproteobacteria,3T1RX@506|Alcaligenaceae	28216|Betaproteobacteria	D	recombinase XerD	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_1344971_1	1249480.B649_03165	8.38e-207	579.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,42M3R@68525|delta/epsilon subdivisions,2YN91@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
k59_1641705_3	1280692.AUJL01000044_gene2346	2.34e-82	259.0	COG0553@1|root,COG0553@2|Bacteria,1TP2C@1239|Firmicutes,24DVA@186801|Clostridia,36FNM@31979|Clostridiaceae	186801|Clostridia	L	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,N6_N4_Mtase,SNF2_N
k59_1112850_1	387093.SUN_1706	5.81e-19	81.3	COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,42R6H@68525|delta/epsilon subdivisions,2YP0H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
k59_1112850_2	1165841.SULAR_05473	8.36e-75	233.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,42M8G@68525|delta/epsilon subdivisions,2YME5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
k59_230085_1	671143.DAMO_1641	5.18e-13	73.9	COG0241@1|root,COG0859@1|root,COG0241@2|Bacteria,COG0859@2|Bacteria,2NPK4@2323|unclassified Bacteria	2|Bacteria	E	D,D-heptose 1,7-bisphosphate phosphatase	rfaF	-	2.7.1.167,2.7.7.70,3.1.3.82,3.1.3.83,5.3.1.28	ko:K02841,ko:K02843,ko:K02849,ko:K03271,ko:K03272,ko:K03273	ko00540,ko01100,map00540,map01100	M00064,M00080	R05644,R05645,R05646,R05647,R09768,R09769,R09771	RC00002,RC00017,RC00078,RC00434	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9,Hydrolase_like
k59_49920_1	553217.ENHAE0001_1525	1.21e-46	165.0	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,1RNZE@1236|Gammaproteobacteria,3NIKK@468|Moraxellaceae	1236|Gammaproteobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0042802,GO:0043021,GO:0043022,GO:0043170,GO:0043335,GO:0043412,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0050896,GO:0051083,GO:0061077,GO:0071704,GO:0140096,GO:1901564	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
k59_1758674_2	420662.Mpe_A2265	4.99e-30	107.0	COG1942@1|root,COG1942@2|Bacteria,1N7K1@1224|Proteobacteria,2WAKW@28216|Betaproteobacteria,1KMRV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Tautomerase enzyme	-	-	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase
k59_1758674_3	159087.Daro_3781	5.42e-67	209.0	COG3971@1|root,COG3971@2|Bacteria,1MVVV@1224|Proteobacteria,2VH5Y@28216|Betaproteobacteria,2KUEN@206389|Rhodocyclales	206389|Rhodocyclales	Q	4-Oxalocrotonate decarboxylase	-	-	4.1.1.77	ko:K01617	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R02602,R05374	RC00751,RC02672	ko00000,ko00001,ko00002,ko01000	-	-	-	FAA_hydrolase
k59_230112_1	640081.Dsui_1446	7.96e-125	360.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,2VH1U@28216|Betaproteobacteria,2KUAR@206389|Rhodocyclales	206389|Rhodocyclales	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
k59_230112_2	1304883.KI912532_gene1684	1.06e-21	90.1	COG0861@1|root,COG0861@2|Bacteria,1MXSK@1224|Proteobacteria,2VHZ5@28216|Betaproteobacteria,2KW4M@206389|Rhodocyclales	206389|Rhodocyclales	P	Integral membrane protein TerC family	-	-	-	-	-	-	-	-	-	-	-	-	TerC
k59_874301_1	1121035.AUCH01000007_gene479	3.17e-57	183.0	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,2VKTW@28216|Betaproteobacteria,2KUXZ@206389|Rhodocyclales	206389|Rhodocyclales	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
k59_938286_1	387093.SUN_1068	1.11e-122	368.0	COG5492@1|root,COG5492@2|Bacteria,1QY8X@1224|Proteobacteria,43CAR@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_938286_2	1165841.SULAR_06403	4.09e-42	139.0	COG0225@1|root,COG0225@2|Bacteria	2|Bacteria	O	peptide-methionine (S)-S-oxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
k59_1228219_1	709032.Sulku_1021	5.63e-114	345.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,42MP3@68525|delta/epsilon subdivisions,2YMP3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
k59_1698039_1	1249480.B649_11630	2.49e-131	374.0	COG0461@1|root,COG0461@2|Bacteria,1RIC5@1224|Proteobacteria,42M91@68525|delta/epsilon subdivisions,2YMTS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
k59_1405325_1	1249480.B649_03760	1.59e-101	315.0	COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,42NB2@68525|delta/epsilon subdivisions,2YMVN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
k59_821631_1	443143.GM18_4010	5.05e-36	135.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,42QZV@68525|delta/epsilon subdivisions,2WN5Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
k59_464863_1	1502852.FG94_02569	3.24e-43	149.0	COG1338@1|root,COG1338@2|Bacteria,1MVBU@1224|Proteobacteria,2VIU6@28216|Betaproteobacteria,473JQ@75682|Oxalobacteraceae	28216|Betaproteobacteria	N	Plays a role in the flagellum-specific transport system	fliP	-	-	ko:K02419	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliP
k59_50004_1	887898.HMPREF0551_2041	1.07e-15	76.3	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,2VIGG@28216|Betaproteobacteria,1K1UR@119060|Burkholderiaceae	28216|Betaproteobacteria	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
k59_50004_2	1080067.BAZH01000036_gene1932	4.16e-41	145.0	COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,1RMRZ@1236|Gammaproteobacteria,3WWP0@544|Citrobacter	1236|Gammaproteobacteria	M	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
k59_1228300_1	1249480.B649_01755	2.49e-34	129.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,42MIH@68525|delta/epsilon subdivisions,2YR84@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing EAL and modified HD-GYP domains	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
k59_1228300_2	1249480.B649_01750	1.25e-41	147.0	COG0784@1|root,COG0784@2|Bacteria,1Q9XN@1224|Proteobacteria,42YUB@68525|delta/epsilon subdivisions,2YRFD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_107002_1	136084.Q9G0F7_9CAUD	1.38e-25	112.0	4QH2I@10239|Viruses,4QWWD@35237|dsDNA viruses  no RNA stage,4QQE9@28883|Caudovirales,4QNFX@10744|Podoviridae	10744|Podoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_133497_1	1537917.JU82_07835	6.01e-104	325.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2YMQV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_955031_2	1537917.JU82_06440	2.2e-101	301.0	COG1886@1|root,COG1886@2|Bacteria,1NF4E@1224|Proteobacteria,42R4G@68525|delta/epsilon subdivisions,2YN6N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar motor switch protein	fliY	-	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FliMN_C
k59_955031_4	1537917.JU82_06435	1.91e-66	208.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,42P56@68525|delta/epsilon subdivisions,2YNV5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
k59_1188015_1	1249480.B649_07305	1.7e-116	334.0	COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,42PGH@68525|delta/epsilon subdivisions,2YN8W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Molybdenum cofactor biosynthesis protein	mogA	-	2.7.7.75	ko:K03831	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
k59_1015166_1	666681.M301_0421	7.36e-43	152.0	COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,2VH20@28216|Betaproteobacteria,2KKBD@206350|Nitrosomonadales	206350|Nitrosomonadales	M	PFAM peptidase S13 D-Ala-D-Ala carboxypeptidase C	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
k59_424728_1	1211817.CCAT010000083_gene1518	1.98e-76	238.0	COG0714@1|root,COG0714@2|Bacteria,1TPKR@1239|Firmicutes,248IM@186801|Clostridia,36DXF@31979|Clostridiaceae	186801|Clostridia	S	associated with various cellular activities	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_715402_2	1249480.B649_10095	1.04e-55	180.0	2ANX8@1|root,31DXW@2|Bacteria,1QB8A@1224|Proteobacteria,42WEI@68525|delta/epsilon subdivisions,2YQAD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	YfaZ
k59_70787_1	1249480.B649_07505	4.65e-75	230.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,42PSG@68525|delta/epsilon subdivisions,2YMFJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
k59_70787_2	709032.Sulku_0927	4.53e-153	455.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42MS0@68525|delta/epsilon subdivisions,2YMTX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,dCache_3
k59_545686_2	96561.Dole_2379	3.22e-28	107.0	2E4SV@1|root,32ZM7@2|Bacteria,1N8VN@1224|Proteobacteria,42VKR@68525|delta/epsilon subdivisions,2WS4C@28221|Deltaproteobacteria,2MMAS@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Putative transmembrane protein (PGPGW)	-	-	-	-	-	-	-	-	-	-	-	-	PGPGW
k59_545686_3	1165841.SULAR_01943	2.91e-51	169.0	COG1090@1|root,COG1090@2|Bacteria,1MUB4@1224|Proteobacteria,42QUU@68525|delta/epsilon subdivisions,2YNXM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Epimerase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
k59_776090_1	1165841.SULAR_08682	8.13e-52	167.0	COG0352@1|root,COG0352@2|Bacteria,1P3Q4@1224|Proteobacteria,42SIF@68525|delta/epsilon subdivisions,2YPJ7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	thiamine-phosphate diphosphorylase activity	-	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	-
k59_776090_2	563040.Saut_2134	2.51e-17	79.7	COG4106@1|root,COG4106@2|Bacteria,1QZ2S@1224|Proteobacteria,43CEU@68525|delta/epsilon subdivisions,2YTCB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Methyltransferase domain	-	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
k59_1131828_1	159087.Daro_3896	1.7e-72	241.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VJBX@28216|Betaproteobacteria,2KU9U@206389|Rhodocyclales	206389|Rhodocyclales	NT	Methyl-accepting chemotaxis protein	pilJ	-	-	ko:K02660	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	MCPsignal,PilJ
k59_776099_1	709032.Sulku_1568	3.91e-155	446.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,42M2G@68525|delta/epsilon subdivisions,2YMS0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
k59_133547_1	1304883.KI912532_gene3180	2.88e-90	270.0	COG0664@1|root,COG0664@2|Bacteria,1R5P7@1224|Proteobacteria,2VIQI@28216|Betaproteobacteria,2KVHP@206389|Rhodocyclales	206389|Rhodocyclales	K	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
k59_133547_2	305700.B447_04202	7.54e-35	129.0	COG1252@1|root,COG1252@2|Bacteria,1QUKT@1224|Proteobacteria,2WGU5@28216|Betaproteobacteria	28216|Betaproteobacteria	C	pyridine nucleotide-disulfide oxidoreductase family protein	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_1482683_1	944547.ABLL_2797	1.11e-35	129.0	COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,42QA8@68525|delta/epsilon subdivisions,2YNH6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_3
k59_1482683_2	908937.Prede_0707	1.47e-25	95.1	COG1773@1|root,COG1773@2|Bacteria	2|Bacteria	C	rubredoxin	rubR	-	-	-	-	-	-	-	-	-	-	-	Rubredoxin
k59_1482683_3	1249480.B649_05300	1.09e-10	60.1	COG2227@1|root,COG2227@2|Bacteria,1QYD8@1224|Proteobacteria,43CBI@68525|delta/epsilon subdivisions,2YTHI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Ribosomal RNA adenine dimethylase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
k59_365206_1	929558.SMGD1_0211	6.5e-22	102.0	COG0457@1|root,COG2319@1|root,COG0457@2|Bacteria,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DUF4062,DUF4384,SIR2_2
k59_662888_1	159087.Daro_3460	2.53e-80	241.0	2ACKP@1|root,31273@2|Bacteria,1RDTS@1224|Proteobacteria,2VR4F@28216|Betaproteobacteria,2KYTC@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_662888_2	159087.Daro_3461	1.87e-57	189.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2VJR5@28216|Betaproteobacteria,2KUCZ@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
k59_485937_1	90814.KL370892_gene2229	7.53e-61	197.0	COG3954@1|root,COG3954@2|Bacteria,1MWN9@1224|Proteobacteria,1RMS7@1236|Gammaproteobacteria,461IU@72273|Thiotrichales	72273|Thiotrichales	C	PFAM Phosphoribulokinase uridine kinase	-	-	2.7.1.19	ko:K00855	ko00710,ko01100,ko01120,ko01200,map00710,map01100,map01120,map01200	M00165,M00166	R01523	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK
k59_485937_2	717773.Thicy_0449	6.46e-91	280.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1S0BJ@1236|Gammaproteobacteria,460IC@72273|Thiotrichales	72273|Thiotrichales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_1304464_1	1165096.ARWF01000001_gene2275	1.3e-29	120.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,2VK35@28216|Betaproteobacteria,2KKP3@206350|Nitrosomonadales	206350|Nitrosomonadales	S	PFAM Flavocytochrome c sulphide dehydrogenase, flavin-binding	-	-	-	-	-	-	-	-	-	-	-	-	FCSD-flav_bind,Pyr_redox_2
k59_1425267_1	573061.Clocel_2482	7.91e-33	130.0	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,2490U@186801|Clostridia,36EG3@31979|Clostridiaceae	186801|Clostridia	Q	TIGRFAM amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_249444_1	622637.KE124774_gene3063	3.89e-67	233.0	COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MWDY@1224|Proteobacteria,2TTGI@28211|Alphaproteobacteria,36X8C@31993|Methylocystaceae	28211|Alphaproteobacteria	IQ	Phosphate acyltransferases	aas	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
k59_1839421_1	472759.Nhal_3529	2e-49	161.0	COG0360@1|root,COG0360@2|Bacteria,1RH82@1224|Proteobacteria,1S5VU@1236|Gammaproteobacteria,1WYA2@135613|Chromatiales	135613|Chromatiales	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
k59_1839421_2	999141.GME_05225	4.13e-16	70.5	COG0257@1|root,COG0257@2|Bacteria,1NGBJ@1224|Proteobacteria,1SCR7@1236|Gammaproteobacteria,1XQP8@135619|Oceanospirillales	135619|Oceanospirillales	J	Belongs to the bacterial ribosomal protein bL36 family	-	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
k59_1839421_3	264730.PSPPH_4928	3.5e-11	62.8	COG2807@1|root,COG2807@2|Bacteria,1QU0F@1224|Proteobacteria,1T1JZ@1236|Gammaproteobacteria,1Z4ZA@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	P	Major Facilitator Superfamily	yhjX	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_1018152_1	1121935.AQXX01000086_gene5236	5.03e-47	175.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RN52@1236|Gammaproteobacteria,1XJDW@135619|Oceanospirillales	135619|Oceanospirillales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
k59_897250_1	998088.B565_2133	7.28e-42	146.0	COG0309@1|root,COG0309@2|Bacteria,1MVCC@1224|Proteobacteria,1RQBE@1236|Gammaproteobacteria,1Y53C@135624|Aeromonadales	135624|Aeromonadales	O	Hydrogenase expression formation protein HypE	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
k59_897250_2	709032.Sulku_2640	2.51e-76	233.0	COG0449@1|root,COG0449@2|Bacteria,1RGWX@1224|Proteobacteria,42TA9@68525|delta/epsilon subdivisions,2YRTG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	ORF6N domain	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
k59_1660477_1	717773.Thicy_1472	6.37e-110	330.0	COG1611@1|root,COG1611@2|Bacteria,1MVQJ@1224|Proteobacteria,1RQHX@1236|Gammaproteobacteria,4606N@72273|Thiotrichales	72273|Thiotrichales	S	Domain of unknown function (DUF4478)	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	DUF3412,DUF4478,Lysine_decarbox
k59_1366372_1	1249480.B649_01060	3.76e-70	218.0	COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,42M1Y@68525|delta/epsilon subdivisions,2YMJA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Hydrolase	aguB	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
k59_1366373_1	709032.Sulku_0723	6e-170	487.0	COG4972@1|root,COG4972@2|Bacteria,1QA6M@1224|Proteobacteria,42NDB@68525|delta/epsilon subdivisions,2YMP2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Pilus assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1484826_1	1165841.SULAR_07595	2.32e-116	340.0	COG0492@1|root,COG0492@2|Bacteria,1NDW6@1224|Proteobacteria,42MUD@68525|delta/epsilon subdivisions,2YMV2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	pyridine nucleotide-disulfide oxidoreductase	trxB_2	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	FixS,Pyr_redox_3
k59_548435_1	1268622.AVS7_03320	1.09e-28	114.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VH80@28216|Betaproteobacteria,4AAWF@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
k59_548435_2	573065.Astex_3427	1.56e-09	60.1	COG1028@1|root,COG1028@2|Bacteria,1MU5Y@1224|Proteobacteria,2TRNQ@28211|Alphaproteobacteria,2KFS5@204458|Caulobacterales	204458|Caulobacterales	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	1.1.1.30	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	M00088	R01361	RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short,adh_short_C2
k59_1252678_1	749222.Nitsa_1216	4.9e-87	265.0	COG1636@1|root,COG1636@2|Bacteria,1MUG5@1224|Proteobacteria,42M1E@68525|delta/epsilon subdivisions,2YN69@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queH	-	1.17.99.6	ko:K09765	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF208
k59_1252678_2	1165841.SULAR_03188	2.8e-21	91.7	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,42P35@68525|delta/epsilon subdivisions,2YN2K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	iIT341.HP0867	LpxB
k59_1660509_1	887898.HMPREF0551_0439	9.94e-08	52.8	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2VH4Z@28216|Betaproteobacteria,1K1ES@119060|Burkholderiaceae	28216|Betaproteobacteria	E	PFAM aminotransferase class I and II	alaA	-	2.6.1.2,2.6.1.66	ko:K14260	ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230	-	R00258,R01215	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_1660509_2	1158165.KB898874_gene1830	3.43e-39	143.0	COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,1RPEU@1236|Gammaproteobacteria,1WWHB@135613|Chromatiales	135613|Chromatiales	E	homoserine dehydrogenase	-	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
k59_308177_1	1249480.B649_09615	3.24e-05	44.7	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,42M4S@68525|delta/epsilon subdivisions,2YM8Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	-	-	1.12.5.1	ko:K05922	-	-	-	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
k59_308177_2	709032.Sulku_2052	4.1e-110	326.0	COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,42MI0@68525|delta/epsilon subdivisions,2YMAS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Small subunit	hydA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.12.5.1	ko:K05927	-	-	-	-	ko00000,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6,TAT_signal
k59_1190163_3	1537917.JU82_11505	3.42e-08	53.9	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,42MV7@68525|delta/epsilon subdivisions,2YMFH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
k59_1777420_1	395494.Galf_1396	1.01e-16	78.2	COG3063@1|root,COG3063@2|Bacteria,1MXPC@1224|Proteobacteria,2VNC8@28216|Betaproteobacteria,44VS2@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	TIGRFAM type IV pilus biogenesis stability protein PilW	pilF	-	-	ko:K02656	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	TPR_16,TPR_17,TPR_19,TPR_2,TPR_8
k59_1777420_2	395494.Galf_1395	3.28e-39	140.0	COG1426@1|root,COG1426@2|Bacteria,1N240@1224|Proteobacteria,2VVFV@28216|Betaproteobacteria,44VYD@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Helix-turn-helix domain	-	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
k59_1074010_1	572480.Arnit_1424	2.75e-55	194.0	COG1234@1|root,COG2203@1|root,COG2206@1|root,COG1234@2|Bacteria,COG2203@2|Bacteria,COG2206@2|Bacteria,1MV37@1224|Proteobacteria,42N4N@68525|delta/epsilon subdivisions,2YNBF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	cAMP phosphodiesterases class-II	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HD,HD_5,Lactamase_B_2,PDEase_II
k59_1134455_1	709032.Sulku_2476	4.89e-132	387.0	COG3437@1|root,COG4191@1|root,COG3437@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43DAR@68525|delta/epsilon subdivisions,2YTHT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HD
k59_1839483_1	509191.AEDB02000085_gene2708	7e-78	262.0	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,2490U@186801|Clostridia,3WGCA@541000|Ruminococcaceae	186801|Clostridia	Q	TIGRFAM amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,ketoacyl-synt
k59_136196_1	1304872.JAGC01000009_gene1160	1.04e-65	202.0	COG1733@1|root,COG1733@2|Bacteria,1MZ6N@1224|Proteobacteria,43A7Z@68525|delta/epsilon subdivisions,2X2F6@28221|Deltaproteobacteria,2MFG8@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
k59_136196_2	629265.PMA4326_08935	2.11e-36	131.0	COG0702@1|root,COG0702@2|Bacteria,1MW44@1224|Proteobacteria,1RPD9@1236|Gammaproteobacteria,1Z9PC@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	GM	NmrA-like family	qorB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.6.5.2	ko:K19267	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10,NmrA
k59_1252733_1	296591.Bpro_0678	2.01e-85	272.0	COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,2VH5H@28216|Betaproteobacteria,4A9PE@80864|Comamonadaceae	28216|Betaproteobacteria	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
k59_1718681_1	1249480.B649_09670	1.32e-133	405.0	COG1251@1|root,COG1740@1|root,COG1251@2|Bacteria,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,42PSD@68525|delta/epsilon subdivisions,2YNBA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	hydrogenase (NiFe) small subunit HydA	-	-	1.12.5.1	ko:K05927	-	-	-	-	ko00000,ko01000	-	-	-	Fer2_BFD,NiFe_hyd_SSU_C,Oxidored_q6,Pyr_redox_2
k59_1428057_1	1121405.dsmv_3564	4.37e-87	265.0	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,42MIX@68525|delta/epsilon subdivisions,2WJ5K@28221|Deltaproteobacteria,2MI89@213118|Desulfobacterales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
k59_136247_1	159087.Daro_3660	8.85e-08	52.4	COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,2VHBC@28216|Betaproteobacteria,2KUFJ@206389|Rhodocyclales	206389|Rhodocyclales	S	phosphotransferase related to Ser Thr protein kinases	-	-	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
k59_136247_2	159087.Daro_3661	1.99e-117	339.0	COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,2VJUN@28216|Betaproteobacteria,2KV5Z@206389|Rhodocyclales	206389|Rhodocyclales	JM	Nucleotidyl transferase	-	-	2.7.7.99	ko:K00992	ko00520,ko01100,map00520,map01100	-	R11025	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
k59_426879_1	29581.BW37_04909	6.68e-11	58.9	COG0745@1|root,COG0745@2|Bacteria,1RDNP@1224|Proteobacteria,2VR8X@28216|Betaproteobacteria,474B1@75682|Oxalobacteraceae	28216|Betaproteobacteria	KT	Response regulator receiver domain	cheY	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
k59_426879_2	1304883.KI912532_gene172	9.86e-100	296.0	COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1N81M@1224|Proteobacteria,2VI4E@28216|Betaproteobacteria,2KV3U@206389|Rhodocyclales	206389|Rhodocyclales	T	Chemotaxis signal transduction protein	-	-	-	ko:K03415	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CheW,Response_reg
k59_957643_1	1123514.KB905901_gene115	1.13e-59	200.0	COG0642@1|root,COG0642@2|Bacteria,1QTSX@1224|Proteobacteria,1T1G3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	qseC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.13.3	ko:K07645	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	2CSK_N,HATPase_c,HisKA
k59_839912_1	1165841.SULAR_10564	1.1e-35	131.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,42MS9@68525|delta/epsilon subdivisions,2YMBY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
k59_839912_2	1165841.SULAR_10559	4.79e-26	98.6	2BRG4@1|root,32MA7@2|Bacteria,1Q36H@1224|Proteobacteria,42WUT@68525|delta/epsilon subdivisions,2YQQJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_665676_1	998088.B565_3445	7.18e-76	241.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,1RN2E@1236|Gammaproteobacteria,1Y3RX@135624|Aeromonadales	135624|Aeromonadales	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
k59_665676_2	59538.XP_005967236.1	6.99e-08	53.9	COG0621@1|root,KOG2492@2759|Eukaryota,38E0X@33154|Opisthokonta,3BEN9@33208|Metazoa,3CXYH@33213|Bilateria,485R3@7711|Chordata,4956Z@7742|Vertebrata,3J2G5@40674|Mammalia	59538.XP_005967236.1|-	T	CDK5 regulatory subunit associated protein 1	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_897359_2	1249480.B649_07690	7.15e-27	105.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,42MB0@68525|delta/epsilon subdivisions,2YMC0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
k59_1134539_1	760154.Sulba_0911	6.12e-25	99.4	2AIWS@1|root,319ED@2|Bacteria,1Q2HE@1224|Proteobacteria,42VQ7@68525|delta/epsilon subdivisions,2YQ77@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1252791_2	159087.Daro_4129	6.14e-112	330.0	COG1168@1|root,COG1168@2|Bacteria,1MY33@1224|Proteobacteria,2VHZ6@28216|Betaproteobacteria,2KV85@206389|Rhodocyclales	206389|Rhodocyclales	E	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities	-	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_1545921_1	159087.Daro_1532	1.42e-67	209.0	COG5490@1|root,COG5490@2|Bacteria,1R4SV@1224|Proteobacteria,2VQP2@28216|Betaproteobacteria,2KW96@206389|Rhodocyclales	206389|Rhodocyclales	S	Phasin protein	-	-	-	-	-	-	-	-	-	-	-	-	Phasin_2
k59_665691_1	1168289.AJKI01000040_gene3163	1.03e-41	144.0	COG3926@1|root,COG3926@2|Bacteria,4NRDK@976|Bacteroidetes,2G1MY@200643|Bacteroidia,3XKTR@558415|Marinilabiliaceae	976|Bacteroidetes	S	Predicted Peptidoglycan domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_108,PG_binding_3
k59_1366503_1	709032.Sulku_1586	3.19e-145	413.0	COG2227@1|root,COG2227@2|Bacteria,1NN3B@1224|Proteobacteria,43C3V@68525|delta/epsilon subdivisions,2YTAM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs	cmoB	-	-	ko:K15257	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_9
k59_308266_2	709032.Sulku_2334	2.36e-24	101.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42MFK@68525|delta/epsilon subdivisions,2YN87@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Abc transporter	nikZ	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k59_1134564_1	709032.Sulku_2437	5.58e-63	202.0	COG2220@1|root,COG2220@2|Bacteria,1MV20@1224|Proteobacteria,42QPP@68525|delta/epsilon subdivisions,2YP9R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
k59_1134564_2	709032.Sulku_2434	2.12e-12	65.9	COG0679@1|root,COG0679@2|Bacteria,1PHSS@1224|Proteobacteria,42M30@68525|delta/epsilon subdivisions,2YN5E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	auxin efflux carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
k59_1601296_1	1249480.B649_05075	1e-05	46.6	COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,42M43@68525|delta/epsilon subdivisions,2YM8G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the aconitase IPM isomerase family	acnB	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0045333,GO:0046395,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072329,GO:0072350,GO:0097159,GO:1901363,GO:1901575	4.2.1.3,4.2.1.99	ko:K01682	ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173	R01324,R01325,R01900,R04425	RC00497,RC00498,RC00618,RC01153	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_2_N,Aconitase_B_N
k59_1601296_2	1249480.B649_05070	6.18e-102	311.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2YNK5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DEAD box helicase family	dbpA	-	3.6.4.13	ko:K05591	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DEAD,DbpA,Helicase_C
k59_1074129_1	340177.Cag_1242	1.29e-14	78.6	COG0689@1|root,COG0726@1|root,COG1785@1|root,COG2133@1|root,COG2304@1|root,COG2911@1|root,COG2931@1|root,COG3210@1|root,COG3898@1|root,COG4254@1|root,COG4932@1|root,COG0689@2|Bacteria,COG0726@2|Bacteria,COG1785@2|Bacteria,COG2133@2|Bacteria,COG2304@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3898@2|Bacteria,COG4254@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	rph	GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575	2.7.7.56,3.1.3.1,3.4.24.40,3.6.1.66	ko:K00989,ko:K01077,ko:K01406,ko:K02428,ko:K20276,ko:K21430	ko00230,ko00730,ko00790,ko01100,ko01503,ko02020,ko02024,map00230,map00730,map00790,map01100,map01503,map02020,map02024	M00126	R00426,R00720,R01855,R02100,R02135,R02720,R03531,R04620	RC00002,RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko01002,ko03016,ko04147	-	-	-	RNase_PH,RNase_PH_C
k59_548591_2	1537917.JU82_00825	4.49e-35	123.0	COG0748@1|root,COG0748@2|Bacteria,1REH2@1224|Proteobacteria,42WSK@68525|delta/epsilon subdivisions,2YQ8W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07226	-	-	-	-	ko00000	-	-	-	DUF2470,Putative_PNPOx
k59_1660654_1	1424334.W822_11080	1.39e-16	78.6	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,2VR2R@28216|Betaproteobacteria,3T3VX@506|Alcaligenaceae	28216|Betaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
k59_665740_1	1121013.P873_09840	9.34e-74	234.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,1RQRP@1236|Gammaproteobacteria,1X30D@135614|Xanthomonadales	135614|Xanthomonadales	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
k59_251656_1	1537917.JU82_04345	3.93e-26	103.0	COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1RD7I@1224|Proteobacteria,42SM8@68525|delta/epsilon subdivisions,2YPEY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Response regulator receiver	-	-	-	ko:K03415	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CheW,Response_reg
k59_1718759_2	1249480.B649_08005	4.32e-77	234.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,42NR9@68525|delta/epsilon subdivisions,2YN03@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
k59_266260_1	387093.SUN_1986	3.61e-29	115.0	COG0069@1|root,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2YNFI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	COGs COG0069 Glutamate synthase domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase
k59_853700_1	572547.Amico_0530	1.21e-58	195.0	COG2265@1|root,COG2265@2|Bacteria,3TAEF@508458|Synergistetes	508458|Synergistetes	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_U5-meth_tr
k59_1039576_1	1123248.KB893359_gene1993	1.01e-36	130.0	COG1484@1|root,COG1484@2|Bacteria,4NFE0@976|Bacteroidetes,1IP5Q@117747|Sphingobacteriia	976|Bacteroidetes	L	PFAM IstB-like ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
k59_1039576_2	1121889.AUDM01000045_gene230	3.3e-20	89.7	COG4584@1|root,COG4584@2|Bacteria,4NEY6@976|Bacteroidetes,1HYXS@117743|Flavobacteriia,2NWWZ@237|Flavobacterium	976|Bacteroidetes	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_23,rve
k59_442018_3	1300005.R9RGE0_9CAUD	1.23e-143	432.0	4QGA5@10239|Viruses,4QURD@35237|dsDNA viruses  no RNA stage,4QT9N@28883|Caudovirales,4QP47@10744|Podoviridae	10744|Podoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1498743_1	1165841.SULAR_04267	1.51e-52	181.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,42N7A@68525|delta/epsilon subdivisions,2YMRE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	lytic murein transglycosylase	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
k59_505756_1	983545.Glaag_1951	1.6e-43	155.0	COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,1RPUP@1236|Gammaproteobacteria,465AR@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components	nrtC	-	-	ko:K15576	ko00910,ko02010,map00910,map02010	M00438	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16.1,3.A.1.16.2	-	-	NMT1_2
k59_505756_2	62928.azo0942	1.8e-65	212.0	COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,2VIJH@28216|Betaproteobacteria,2KUJ5@206389|Rhodocyclales	206389|Rhodocyclales	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components	nasF	-	-	ko:K15576	ko00910,ko02010,map00910,map02010	M00438	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16.1,3.A.1.16.2	-	-	NMT1_2,TAT_signal
k59_568241_1	709032.Sulku_1225	9.83e-74	234.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42MH9@68525|delta/epsilon subdivisions,2YMWG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	COG1459 Type II secretory pathway, component PulF	-	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
k59_1858710_1	1168067.JAGP01000001_gene705	9.56e-49	160.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,1RQ7F@1236|Gammaproteobacteria,460JN@72273|Thiotrichales	72273|Thiotrichales	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
k59_797550_1	1121012.AUKX01000098_gene2633	1.93e-107	327.0	COG5421@1|root,COG5421@2|Bacteria,4PAGJ@976|Bacteroidetes,1IAIH@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_208988_1	159087.Daro_2038	1.14e-74	241.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,2VIM4@28216|Betaproteobacteria,2KURJ@206389|Rhodocyclales	206389|Rhodocyclales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH,HHH_5,UVR,UvrC_HhH_N
k59_208988_2	159087.Daro_2039	4.77e-41	139.0	COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,2VQI2@28216|Betaproteobacteria,2KW4F@206389|Rhodocyclales	206389|Rhodocyclales	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
k59_28677_1	765913.ThidrDRAFT_2938	1.14e-10	64.3	COG3338@1|root,COG3338@2|Bacteria,1PEA6@1224|Proteobacteria,1RSM9@1236|Gammaproteobacteria,1WX85@135613|Chromatiales	135613|Chromatiales	P	PFAM carbonic anhydrase	-	-	4.2.1.1	ko:K01674	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Carb_anhydrase
k59_1858743_1	2340.JV46_14180	2.79e-24	107.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1J56I@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	(GGDEF) domain	-	-	3.1.4.52	ko:K21024	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_9,SBP_bac_3
k59_622553_1	159087.Daro_1284	3.05e-113	336.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,2VGZI@28216|Betaproteobacteria,2KUMY@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_381240_1	1123517.JOMR01000001_gene301	3.5e-137	399.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,1RN4I@1236|Gammaproteobacteria,4602Z@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
k59_86552_1	709032.Sulku_1864	3.96e-21	88.6	COG0692@1|root,COG0692@2|Bacteria,1MV80@1224|Proteobacteria,42MYK@68525|delta/epsilon subdivisions,2YMMB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	-	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
k59_86552_2	1537917.JU82_02200	5.9e-77	230.0	COG0789@1|root,COG0789@2|Bacteria,1N948@1224|Proteobacteria,42SGY@68525|delta/epsilon subdivisions,2YPH4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator	hspR	-	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
k59_797623_1	159087.Daro_0855	1.71e-42	147.0	COG0731@1|root,COG0731@2|Bacteria,1QG36@1224|Proteobacteria,2VK7Z@28216|Betaproteobacteria,2KVBZ@206389|Rhodocyclales	206389|Rhodocyclales	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_797623_2	159087.Daro_0856	3.13e-38	129.0	COG2944@1|root,COG2944@2|Bacteria,1N48U@1224|Proteobacteria,2VUHQ@28216|Betaproteobacteria,2KWYQ@206389|Rhodocyclales	206389|Rhodocyclales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
k59_266393_1	1537917.JU82_01185	1.03e-118	347.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,42M5Y@68525|delta/epsilon subdivisions,2YMJB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
k59_1565243_1	1165841.SULAR_09264	5.39e-142	405.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,42MEE@68525|delta/epsilon subdivisions,2YN8Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
k59_1090326_1	1249480.B649_07715	3.66e-139	408.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,42MGF@68525|delta/epsilon subdivisions,2YN0E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the UbiD family	menA	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0396	UbiD
k59_1565259_1	1537917.JU82_09960	3.24e-122	356.0	COG4974@1|root,COG4974@2|Bacteria,1QU6A@1224|Proteobacteria,42RBN@68525|delta/epsilon subdivisions,2YP23@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_975535_1	1165841.SULAR_03652	1.09e-30	117.0	2DKFZ@1|root,309D6@2|Bacteria,1QZK6@1224|Proteobacteria,43CQP@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Domain of unknown function (DUF4382)	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,DUF4382
k59_1792375_1	1249480.B649_11360	1.62e-65	221.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YMHP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF,PAS_4
k59_1792375_3	1537917.JU82_07565	4.22e-133	383.0	COG1723@1|root,COG1723@2|Bacteria,1MWYM@1224|Proteobacteria,42URC@68525|delta/epsilon subdivisions,2YPX0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Uncharacterised ACR, YagE family COG1723	-	-	-	-	-	-	-	-	-	-	-	-	DUF155
k59_209107_1	159087.Daro_0238	4.11e-36	128.0	COG0861@1|root,COG0861@2|Bacteria,1MWC9@1224|Proteobacteria,2VJSY@28216|Betaproteobacteria,2KUK4@206389|Rhodocyclales	206389|Rhodocyclales	P	Integral membrane protein TerC family	-	-	-	-	-	-	-	-	-	-	-	-	TerC
k59_209107_2	1304883.KI912532_gene548	2.92e-60	190.0	2BX6S@1|root,324B7@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1439)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1439
k59_86610_1	1537917.JU82_03250	5.02e-44	156.0	COG2199@1|root,COG2200@1|root,COG3620@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,COG3620@2|Bacteria,1MVJY@1224|Proteobacteria,42N7E@68525|delta/epsilon subdivisions,2YNE7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PFAM EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF
k59_86610_2	1537917.JU82_03255	3.09e-127	363.0	COG1179@1|root,COG1179@2|Bacteria,1MWXR@1224|Proteobacteria,42PHC@68525|delta/epsilon subdivisions,2YNF2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	involved in molybdopterin and thiamine biosynthesis family 1	-	-	-	-	-	-	-	-	-	-	-	-	ThiF
k59_381310_2	1165841.SULAR_07810	1.97e-167	478.0	COG0457@1|root,COG0457@2|Bacteria,1NR72@1224|Proteobacteria	1224|Proteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1734242_1	583345.Mmol_1621	1.96e-36	130.0	2E4XE@1|root,32ZRB@2|Bacteria,1N7HI@1224|Proteobacteria,2VVPN@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1152696_1	1537917.JU82_05680	1.63e-48	164.0	COG0500@1|root,COG2226@2|Bacteria,1NV27@1224|Proteobacteria,42P39@68525|delta/epsilon subdivisions,2YNRW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
k59_86629_1	1165841.SULAR_00860	1.7e-49	164.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,42NTG@68525|delta/epsilon subdivisions,2YNB7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	abc transporter atp-binding protein	iamA	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
k59_86629_2	387093.SUN_1357	4.2e-44	152.0	COG1463@1|root,COG1463@2|Bacteria,1MU4B@1224|Proteobacteria,42RPB@68525|delta/epsilon subdivisions,2YP5G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	ABC-type transport system involved in resistance to organic solvents periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
k59_1272332_1	159087.Daro_3020	2.9e-58	188.0	COG2307@1|root,COG2307@2|Bacteria,1MVZK@1224|Proteobacteria,2VIB5@28216|Betaproteobacteria,2KV8E@206389|Rhodocyclales	206389|Rhodocyclales	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
k59_1272332_2	987059.RBXJA2T_04048	4.41e-35	130.0	COG2308@1|root,COG2308@2|Bacteria,1MUAD@1224|Proteobacteria,2VI55@28216|Betaproteobacteria,1KJ54@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
k59_209153_1	1163617.SCD_n02841	2.27e-21	90.5	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,2VJS2@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
k59_209153_2	580332.Slit_2947	9.11e-32	111.0	COG1942@1|root,COG1942@2|Bacteria,1NC22@1224|Proteobacteria,2VWHU@28216|Betaproteobacteria,44WJF@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Tautomerase enzyme	-	-	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase
k59_209166_1	1120973.AQXL01000112_gene1087	6.24e-09	55.1	COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,4HFQD@91061|Bacilli,2793R@186823|Alicyclobacillaceae	91061|Bacilli	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
k59_209166_2	326297.Sama_0227	1.95e-58	184.0	COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,1S452@1236|Gammaproteobacteria,2QBN5@267890|Shewanellaceae	1236|Gammaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009894,GO:0009987,GO:0010467,GO:0010468,GO:0010608,GO:0015935,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031329,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043487,GO:0043488,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061013,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903311,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
k59_209166_3	314287.GB2207_06203	4.7e-36	125.0	COG0199@1|root,COG0199@2|Bacteria,1MZDT@1224|Proteobacteria,1S62N@1236|Gammaproteobacteria,1J6KB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
k59_505951_2	1249480.B649_00195	3.55e-42	146.0	COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,42PGR@68525|delta/epsilon subdivisions,2YRIC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PFAM metal-dependent phosphohydrolase HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
k59_1448020_1	396595.TK90_1685	2.32e-32	117.0	COG1943@1|root,COG1943@2|Bacteria,1RCWW@1224|Proteobacteria,1S3ZJ@1236|Gammaproteobacteria,1WY9M@135613|Chromatiales	135613|Chromatiales	L	PFAM Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
k59_1448020_2	1198452.Jab_1c23290	2.1e-32	114.0	2DBSM@1|root,30K0E@2|Bacteria,1PX6A@1224|Proteobacteria,2WCP9@28216|Betaproteobacteria,477ZV@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	KTSC domain	-	-	-	-	-	-	-	-	-	-	-	-	KTSC
k59_1675779_1	1249480.B649_00980	3.76e-61	190.0	COG4875@1|root,COG4875@2|Bacteria,1RFS2@1224|Proteobacteria,43B6N@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Calcium/calmodulin dependent protein kinase II association domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
k59_1093832_1	1387312.BAUS01000004_gene1517	7.44e-105	307.0	COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria,2VIP4@28216|Betaproteobacteria,2KKBY@206350|Nitrosomonadales	206350|Nitrosomonadales	V	N-6 DNA Methylase	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
k59_1093832_2	1387312.BAUS01000004_gene1518	9.6e-51	182.0	COG0732@1|root,COG0732@2|Bacteria,1MXVH@1224|Proteobacteria,2VM15@28216|Betaproteobacteria,2KKCH@206350|Nitrosomonadales	206350|Nitrosomonadales	V	Type I restriction modification DNA specificity domain	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
k59_1737832_1	1249627.D779_4113	1.96e-76	255.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,1WVZ3@135613|Chromatiales	135613|Chromatiales	L	DNA polymerase III alpha subunit	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,Intein_splicing,LAGLIDADG_3,PHP,tRNA_anti-codon
k59_1093847_1	709032.Sulku_0276	5.6e-78	249.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2YN0B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
k59_1568998_1	709032.Sulku_0316	4.14e-125	369.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,42M74@68525|delta/epsilon subdivisions,2YMI1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Peptidase, M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_1209379_1	580332.Slit_1347	1.44e-95	288.0	COG1902@1|root,COG1902@2|Bacteria,1MVIX@1224|Proteobacteria,2VH2S@28216|Betaproteobacteria,44V89@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	-	ko:K10680	ko00633,ko01120,map00633,map01120	-	R08014,R08017,R08042	RC00250	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN
k59_509424_1	1249480.B649_00180	1.75e-133	393.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,42M81@68525|delta/epsilon subdivisions,2YMTF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_1276316_1	1304883.KI912532_gene1017	2.82e-133	384.0	COG1703@1|root,COG1703@2|Bacteria,1MVI0@1224|Proteobacteria,2VIRF@28216|Betaproteobacteria,2KVDF@206389|Rhodocyclales	206389|Rhodocyclales	E	periplasmic protein kinase ArgK and related GTPases of G3E family	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
k59_689284_1	1304883.KI912532_gene3253	2.29e-46	152.0	2EIBB@1|root,33C2R@2|Bacteria,1NETH@1224|Proteobacteria,2VXET@28216|Betaproteobacteria,2KXHM@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_689287_1	159087.Daro_0740	5.81e-107	328.0	COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,2VHVC@28216|Betaproteobacteria,2KUWV@206389|Rhodocyclales	206389|Rhodocyclales	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
k59_509448_1	709032.Sulku_1844	2.89e-62	198.0	COG1792@1|root,COG1792@2|Bacteria,1QB26@1224|Proteobacteria,42MF4@68525|delta/epsilon subdivisions,2YNT9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Rod shape-determining protein MreC	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
k59_915644_1	1537915.JU57_13835	6.1e-109	327.0	COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria,42N9K@68525|delta/epsilon subdivisions,2YMIW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	type I restriction-modification system	hsdM	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
k59_157387_1	709032.Sulku_2201	2.55e-55	181.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,42N1I@68525|delta/epsilon subdivisions,2YMA0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome	ccpA	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
k59_1737934_1	1537917.JU82_01665	1.97e-193	578.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2YMP9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5,RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_856612_1	1249480.B649_11640	1.52e-93	289.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,42MEM@68525|delta/epsilon subdivisions,2YMWQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
k59_384789_1	491952.Mar181_2737	3.72e-61	213.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,1RP9N@1236|Gammaproteobacteria,1XHKJ@135619|Oceanospirillales	135619|Oceanospirillales	OT	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
k59_1093929_1	159087.Daro_0326	2.39e-14	68.2	COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,2VQ0A@28216|Betaproteobacteria,2KW4S@206389|Rhodocyclales	206389|Rhodocyclales	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
k59_1093929_2	159087.Daro_0327	5.54e-32	112.0	COG0255@1|root,COG0255@2|Bacteria,1N6PR@1224|Proteobacteria,2VVNT@28216|Betaproteobacteria,2KXD6@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
k59_1093929_3	159087.Daro_0328	1.77e-50	160.0	COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,2VU2G@28216|Betaproteobacteria,2KX1P@206389|Rhodocyclales	206389|Rhodocyclales	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
k59_1323640_1	1501269.EW15_1491	6.79e-58	194.0	COG1192@1|root,COG1192@2|Bacteria,1G47J@1117|Cyanobacteria	1117|Cyanobacteria	D	PFAM CobQ CobB MinD ParA nucleotide binding domain	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	CbiA,Mrr_cat
k59_1156790_1	1123518.ARWI01000001_gene767	2.91e-94	295.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,1RN0F@1236|Gammaproteobacteria,460G5@72273|Thiotrichales	72273|Thiotrichales	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3329,HATPase_c,HisKA,PAS,PAS_8
k59_1156790_2	614083.AWQR01000005_gene1005	1.44e-21	91.3	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2VIT4@28216|Betaproteobacteria,4A9UT@80864|Comamonadaceae	28216|Betaproteobacteria	K	TIGRFAM phosphate regulon transcriptional regulatory protein PhoB	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_1043806_1	159087.Daro_3978	7.27e-118	345.0	COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,2VJKH@28216|Betaproteobacteria,2KUUA@206389|Rhodocyclales	206389|Rhodocyclales	KO	Hydrogenase accessory protein HypB	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
k59_802069_1	932678.THERU_06755	2.09e-13	65.1	COG4327@1|root,COG4327@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4212)	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	DUF4212,SSF
k59_802069_2	1304883.KI912532_gene2161	7.11e-32	113.0	2EJDA@1|root,33D4B@2|Bacteria,1NJG2@1224|Proteobacteria,2VXQP@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1386636_1	1249480.B649_05420	1.46e-101	302.0	COG0167@1|root,COG0167@2|Bacteria,1MXER@1224|Proteobacteria,42QNP@68525|delta/epsilon subdivisions,2YR5C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
k59_1229622_1	1132855.KB913035_gene835	1.22e-110	330.0	COG3225@1|root,COG3225@2|Bacteria,1MUXW@1224|Proteobacteria,2VMDE@28216|Betaproteobacteria,2KM0A@206350|Nitrosomonadales	206350|Nitrosomonadales	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
k59_1406892_1	1249480.B649_10635	3.46e-102	297.0	COG1558@1|root,COG1558@2|Bacteria,1RHI3@1224|Proteobacteria,42TPI@68525|delta/epsilon subdivisions,2YP1Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Belongs to the flagella basal body rod proteins family	flgC	-	-	ko:K02388	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k59_1406892_3	1537917.JU82_01615	1.27e-180	518.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,42M1T@68525|delta/epsilon subdivisions,2YMJ5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Cell division protein FtsI penicillin-binding protein	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
k59_1814501_1	1123517.JOMR01000001_gene62	2.6e-70	221.0	COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,1RMZ1@1236|Gammaproteobacteria,4602J@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
k59_1114266_1	1249480.B649_09005	8.14e-11	59.3	COG3323@1|root,COG3323@2|Bacteria,1MZF5@1224|Proteobacteria,42W00@68525|delta/epsilon subdivisions,2YS8D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1114266_2	1122211.JMLW01000022_gene2538	8.07e-21	90.9	COG0042@1|root,COG0042@2|Bacteria,1MUY1@1224|Proteobacteria,1RN28@1236|Gammaproteobacteria,1XI2R@135619|Oceanospirillales	135619|Oceanospirillales	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs	dusA	-	-	ko:K05539	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
k59_50900_1	159087.Daro_0858	8.1e-121	353.0	COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,2VJA4@28216|Betaproteobacteria,2KUQ4@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
k59_1523172_2	709032.Sulku_1287	1.52e-48	161.0	COG2227@1|root,COG2227@2|Bacteria,1QYD8@1224|Proteobacteria,43CBI@68525|delta/epsilon subdivisions,2YTHI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Ribosomal RNA adenine dimethylase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
k59_1406910_1	743720.Psefu_4179	6.66e-21	94.7	2AK27@1|root,31ARV@2|Bacteria,1REZR@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1346346_1	159087.Daro_3963	2.56e-129	383.0	COG0223@1|root,COG1024@1|root,COG0223@2|Bacteria,COG1024@2|Bacteria,1MWYJ@1224|Proteobacteria,2VK38@28216|Betaproteobacteria,2KVS4@206389|Rhodocyclales	206389|Rhodocyclales	IJ	Formyl transferase, C-terminal domain	-	-	-	ko:K19640	-	-	-	-	ko00000,ko02022	-	-	-	ECH_1,Formyl_trans_C,Formyl_trans_N
k59_1346351_1	1249480.B649_01845	5.82e-83	258.0	COG2199@1|root,COG3706@2|Bacteria,1MWHH@1224|Proteobacteria,42RQ2@68525|delta/epsilon subdivisions,2YP69@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG2199 FOG GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,GGDEF
k59_1760134_1	1158345.JNLL01000001_gene10	1.82e-92	285.0	arCOG03638@1|root,2Z8W3@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1538)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1538
k59_1699507_2	1158338.JNLJ01000001_gene866	2.87e-111	337.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	pglJ	GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.4.1.291	ko:K17248	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
k59_1229656_1	1565314.OA34_05500	1.96e-21	86.7	COG1837@1|root,COG1837@2|Bacteria,1N7IX@1224|Proteobacteria,42VEW@68525|delta/epsilon subdivisions,2YQ7J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	RNA-binding protein	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
k59_1229656_2	1123326.JFBL01000001_gene1505	7.38e-51	168.0	COG0806@1|root,COG0806@2|Bacteria,1MYUH@1224|Proteobacteria,42SEN@68525|delta/epsilon subdivisions,2YPH6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
k59_1229656_3	387093.SUN_0371	5.14e-130	372.0	COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,42P8R@68525|delta/epsilon subdivisions,2YM7K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
k59_1229656_4	749222.Nitsa_1380	2.55e-31	112.0	COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,42TMU@68525|delta/epsilon subdivisions,2YPEI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
k59_1643153_1	640513.Entas_2900	7.05e-13	71.6	COG1538@1|root,COG1538@2|Bacteria,1MUZZ@1224|Proteobacteria,1RQEP@1236|Gammaproteobacteria,3X3AY@547|Enterobacter	1236|Gammaproteobacteria	M	TIGRFAM RND efflux system, outer membrane lipoprotein, NodT	mdtQ	GO:0008150,GO:0042221,GO:0046677,GO:0050896	-	-	-	-	-	-	-	-	-	-	OEP
k59_1699523_1	709032.Sulku_0040	3.44e-104	310.0	COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,42NI1@68525|delta/epsilon subdivisions,2YMHQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
k59_405426_1	356829.BITS_0011	4.64e-15	78.6	COG5002@1|root,COG5002@2|Bacteria,2GJY7@201174|Actinobacteria,4CZIM@85004|Bifidobacteriales	201174|Actinobacteria	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	senX3	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009405,GO:0009987,GO:0016020,GO:0016310,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0051704,GO:0071704,GO:0071944,GO:1901564	2.7.13.3	ko:K07768	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_405426_2	709032.Sulku_1781	5.8e-120	345.0	COG0745@1|root,COG0745@2|Bacteria,1Q1DT@1224|Proteobacteria,42TCX@68525|delta/epsilon subdivisions,2YPPY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_344440_1	1502770.JQMG01000001_gene300	1.65e-112	329.0	COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,2VHZU@28216|Betaproteobacteria,2KM3K@206350|Nitrosomonadales	206350|Nitrosomonadales	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
k59_344483_1	1537917.JU82_10595	4.74e-112	334.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,42Q9B@68525|delta/epsilon subdivisions,2YNKN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.2.3	ko:K17229	ko00920,ko01120,map00920,map01120	-	R09499	-	ko00000,ko00001,ko01000	-	-	-	FCSD-flav_bind,Pyr_redox_2,TAT_signal
k59_875794_1	159087.Daro_3962	1.37e-131	386.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,2KUEY@206389|Rhodocyclales	206389|Rhodocyclales	T	Bacterial regulatory protein, Fis family	hoxA	-	-	ko:K19641	ko02020,map02020	M00772	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_108194_1	1249480.B649_07615	1.87e-108	331.0	COG1315@1|root,COG1315@2|Bacteria,1R5P6@1224|Proteobacteria,42MAS@68525|delta/epsilon subdivisions,2YM7Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Flagellar Assembly Protein A	-	-	-	-	-	-	-	-	-	-	-	-	FapA
k59_1523240_1	1249480.B649_04990	3.14e-45	149.0	COG0735@1|root,COG0735@2|Bacteria,1N0HW@1224|Proteobacteria,43B75@68525|delta/epsilon subdivisions,2YPV3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Belongs to the Fur family	-	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
k59_1523240_2	709032.Sulku_1168	2.62e-215	600.0	COG3200@1|root,COG3200@2|Bacteria,1MUWF@1224|Proteobacteria,42MB5@68525|delta/epsilon subdivisions,2YMRI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	phospho-2-dehydro-3-deoxyheptonate aldolase	aroG	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0134	DAHP_synth_2
k59_1760231_1	387093.SUN_1504	1.33e-46	164.0	COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,42QJ2@68525|delta/epsilon subdivisions,2YNBV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COGs COG3864 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
k59_1346445_2	929558.SMGD1_1008	9.92e-11	66.2	COG2199@1|root,COG3706@2|Bacteria,1QZ1Q@1224|Proteobacteria,43AM7@68525|delta/epsilon subdivisions,2YR58@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Protein of unknown function (DUF3365)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,GGDEF
k59_1760234_1	159087.Daro_3293	1.66e-56	178.0	COG1051@1|root,COG1051@2|Bacteria,1N03W@1224|Proteobacteria,2VRC0@28216|Betaproteobacteria,2KWI7@206389|Rhodocyclales	206389|Rhodocyclales	F	Belongs to the Nudix hydrolase family. NudJ subfamily	nudJ	-	-	-	-	-	-	-	-	-	-	-	NUDIX
k59_1760234_2	159087.Daro_3294	6.53e-55	179.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,2VHR7@28216|Betaproteobacteria,2KUZJ@206389|Rhodocyclales	206389|Rhodocyclales	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
k59_1346449_1	1537917.JU82_02250	4.43e-71	224.0	2AIAA@1|root,318R4@2|Bacteria,1Q0T4@1224|Proteobacteria,42SFV@68525|delta/epsilon subdivisions,2YPR6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	1.13.11.63	ko:K21817	-	-	-	-	ko00000,ko01000	-	-	-	-
k59_290711_1	1537917.JU82_08665	2.73e-187	529.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,42M7A@68525|delta/epsilon subdivisions,2YNCK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k59_108232_2	1128398.Curi_c12920	1.16e-85	258.0	COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,24APG@186801|Clostridia,267UB@186813|unclassified Clostridiales	186801|Clostridia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
k59_231489_1	748247.AZKH_0236	2.33e-82	256.0	COG0438@1|root,COG0438@2|Bacteria,1PGU0@1224|Proteobacteria,2W939@28216|Betaproteobacteria,2KZB9@206389|Rhodocyclales	206389|Rhodocyclales	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
k59_751229_1	864073.HFRIS_003218	3.35e-84	261.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,2VHEH@28216|Betaproteobacteria,472H0@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
k59_466457_1	395494.Galf_1448	5.35e-67	210.0	COG2771@1|root,COG2771@2|Bacteria,1N6UR@1224|Proteobacteria,2WGVQ@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	ko:K18304	ko02024,ko02025,map02024,map02025	M00644,M00769	-	-	ko00000,ko00001,ko00002,ko01504,ko03000	-	-	-	Autoind_bind,GerE
k59_1523296_1	583345.Mmol_0662	1.76e-126	375.0	COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,2VHZX@28216|Betaproteobacteria,2KKQ1@206350|Nitrosomonadales	206350|Nitrosomonadales	J	TIGRFAM glutaminyl-tRNA synthetase	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
k59_1407125_1	709032.Sulku_1954	6.74e-75	245.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2YNQA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
k59_1407133_1	748247.AZKH_0072	3.36e-55	193.0	COG1148@1|root,COG1148@2|Bacteria,1QUQG@1224|Proteobacteria,2VMBE@28216|Betaproteobacteria,2KVUW@206389|Rhodocyclales	206389|Rhodocyclales	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_10
k59_875908_1	1249480.B649_10280	1.41e-86	278.0	COG4206@1|root,COG4206@2|Bacteria,1QUPS@1224|Proteobacteria,43CID@68525|delta/epsilon subdivisions,2YTCZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_1523314_1	709032.Sulku_2476	6.73e-90	278.0	COG3437@1|root,COG4191@1|root,COG3437@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43DAR@68525|delta/epsilon subdivisions,2YTHT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HD
k59_290769_2	709032.Sulku_1570	1.2e-37	132.0	2AJE1@1|root,319ZU@2|Bacteria,1Q4J6@1224|Proteobacteria,42U7R@68525|delta/epsilon subdivisions,2YQ63@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1346570_1	159087.Daro_3190	3.87e-79	236.0	COG2010@1|root,COG2010@2|Bacteria,1RDSI@1224|Proteobacteria,2VQ50@28216|Betaproteobacteria,2KW5Y@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome c	norC	-	-	ko:K02305	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002	3.D.4.10	-	-	Cytochrom_C
k59_1643359_1	1249480.B649_01035	1.54e-56	192.0	COG0745@1|root,COG0745@2|Bacteria,1QXJT@1224|Proteobacteria,42V47@68525|delta/epsilon subdivisions,2YQ8S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	RESPONSE REGULATOR receiver	-	-	-	ko:K07288	-	-	-	-	ko00000	-	-	-	-
k59_875960_1	709032.Sulku_1589	1.23e-100	306.0	COG1418@1|root,COG1418@2|Bacteria,1P7YA@1224|Proteobacteria,42KZ8@68525|delta/epsilon subdivisions,2YMQS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
k59_875963_1	666681.M301_0446	5.14e-89	280.0	COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,2VHUE@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Cytochrome c-type biogenesis protein CcmF	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
k59_1114533_1	709032.Sulku_2472	2.21e-71	221.0	COG2836@1|root,COG2836@2|Bacteria,1QZ1V@1224|Proteobacteria,430HB@68525|delta/epsilon subdivisions,2YRZU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	DsbD_2
k59_1114535_1	1144325.PMI22_03564	3.49e-29	112.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,1RM8I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
k59_1114535_2	522306.CAP2UW1_3749	6.51e-14	71.6	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,2VI3U@28216|Betaproteobacteria,1KPVC@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_1643425_1	159087.Daro_1936	1.76e-110	332.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,1MVU6@1224|Proteobacteria,2VH37@28216|Betaproteobacteria,2KUE9@206389|Rhodocyclales	206389|Rhodocyclales	C	Electron transfer flavoprotein-ubiquinone oxidoreductase	-	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO,NAD_binding_8
k59_1346653_1	1304883.KI912532_gene1954	2.41e-30	112.0	COG4566@1|root,COG4566@2|Bacteria,1N6WR@1224|Proteobacteria,2VK0C@28216|Betaproteobacteria,2KW5Q@206389|Rhodocyclales	206389|Rhodocyclales	K	response regulator	dctR	-	-	ko:K11712	ko02020,map02020	-	-	-	ko00000,ko00001,ko02022	-	-	-	GerE,Response_reg
k59_108418_1	1537917.JU82_03225	3.76e-102	318.0	COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2YMB9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	chemotaxis protein	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k59_1230017_1	1537917.JU82_03450	4.3e-111	324.0	COG0309@1|root,COG0309@2|Bacteria,1MVCC@1224|Proteobacteria,42M3M@68525|delta/epsilon subdivisions,2YMY3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	hydrogenase expression formation protein	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
k59_1814859_1	1262449.CP6013_1170	5.16e-30	120.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,36E1W@31979|Clostridiaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,PAS_3,PocR,dCache_1
k59_876064_1	43989.cce_0797	1.56e-80	246.0	COG0259@1|root,COG0259@2|Bacteria,1G0HC@1117|Cyanobacteria,3KHWH@43988|Cyanothece	1117|Cyanobacteria	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
k59_876078_1	709032.Sulku_1154	4.52e-24	99.8	COG4773@1|root,COG4773@2|Bacteria,1R8BS@1224|Proteobacteria,42M7T@68525|delta/epsilon subdivisions,2YS9H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	PFAM outer membrane porin	-	-	-	-	-	-	-	-	-	-	-	-	OprD
k59_876078_2	1537917.JU82_05550	6.6e-88	265.0	COG2265@1|root,COG2265@2|Bacteria,1QVA5@1224|Proteobacteria,42RWE@68525|delta/epsilon subdivisions,2YP9J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
k59_231721_1	1249480.B649_08650	2.11e-87	276.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2YN6Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DNA mismatch repair MutS family	-	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_III,MutS_V
k59_1114655_2	575540.Isop_0491	1.56e-47	169.0	COG1331@1|root,COG1331@2|Bacteria,2IX0N@203682|Planctomycetes	203682|Planctomycetes	O	COG1331 Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
k59_405803_1	387093.SUN_1373	7.76e-11	62.0	COG0535@1|root,COG0535@2|Bacteria,1N2I6@1224|Proteobacteria,42P9K@68525|delta/epsilon subdivisions,2YNK6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
k59_876137_1	159087.Daro_0968	4.33e-124	357.0	COG1100@1|root,COG1100@2|Bacteria,1RCJJ@1224|Proteobacteria,2VIVX@28216|Betaproteobacteria,2KY1T@206389|Rhodocyclales	206389|Rhodocyclales	S	ADP-ribosylation factor family	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf
k59_1760590_1	1249480.B649_06005	1.15e-65	221.0	COG2202@1|root,COG2461@1|root,COG5001@1|root,COG2202@2|Bacteria,COG2461@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YN16@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	GGDEF EAL family protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_9
k59_1814950_2	1165841.SULAR_02813	3.29e-65	207.0	COG0108@1|root,COG0108@2|Bacteria,1MU8P@1224|Proteobacteria,42N1C@68525|delta/epsilon subdivisions,2YMUA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
k59_1114715_1	1249480.B649_02250	1.28e-43	153.0	COG0739@1|root,COG0739@2|Bacteria,1NESH@1224|Proteobacteria,42MGB@68525|delta/epsilon subdivisions,2YMT7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_1292720_1	159087.Daro_0244	5.38e-88	287.0	COG0642@1|root,COG0784@1|root,COG3829@1|root,COG4564@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,COG4564@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,DUF4118,GAF,GAF_2,HATPase_c,HisKA,Hpt,NMT1,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,SBP_bac_3
k59_823054_1	1158146.KB907121_gene1192	6.44e-108	330.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,1RMH1@1236|Gammaproteobacteria,1WWKE@135613|Chromatiales	135613|Chromatiales	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
k59_353205_1	1454004.AW11_00612	1.12e-19	87.8	COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,2VKX2@28216|Betaproteobacteria	28216|Betaproteobacteria	M	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_353205_2	1454004.AW11_00611	4.02e-70	225.0	COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,2VP40@28216|Betaproteobacteria	28216|Betaproteobacteria	M	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_470917_1	598659.NAMH_0038	2.77e-13	68.6	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,42NPG@68525|delta/epsilon subdivisions,2YMG4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iIT341.HP1375	Acetyltransf_11,Hexapep
k59_1634_1	1485544.JQKP01000005_gene358	3.23e-26	103.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,2VI78@28216|Betaproteobacteria,44UZC@713636|Nitrosomonadales	28216|Betaproteobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
k59_1634_2	717773.Thicy_0623	1.28e-76	240.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,1RP4D@1236|Gammaproteobacteria,4601W@72273|Thiotrichales	72273|Thiotrichales	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_529817_1	1537917.JU82_10795	2.45e-134	384.0	COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,42M1Y@68525|delta/epsilon subdivisions,2YMJA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Hydrolase	aguB	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
k59_529817_2	1537917.JU82_10800	5.73e-43	146.0	COG2214@1|root,COG2214@2|Bacteria,1QV0K@1224|Proteobacteria,42RGB@68525|delta/epsilon subdivisions	1224|Proteobacteria	O	DnaJ domain protein	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ
k59_1351236_1	709032.Sulku_0780	8.63e-76	246.0	COG4191@1|root,COG4191@2|Bacteria,1PGQH@1224|Proteobacteria,42RWG@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	7TMR-DISM extracellular 2	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM
k59_588201_2	709032.Sulku_1038	4.01e-21	92.0	COG1477@1|root,COG1477@2|Bacteria	2|Bacteria	H	protein flavinylation	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
k59_1234054_1	1249480.B649_01515	1.87e-130	390.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,42N34@68525|delta/epsilon subdivisions,2YMFS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_C
k59_1695_1	1121035.AUCH01000006_gene613	1.36e-44	164.0	COG0642@1|root,COG2202@1|root,COG4251@1|root,COG0642@2|Bacteria,COG2202@2|Bacteria,COG4251@2|Bacteria,1NWNJ@1224|Proteobacteria,2WHQD@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,Response_reg
k59_1116378_1	317025.Tcr_0402	1.43e-33	122.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,1RMAU@1236|Gammaproteobacteria,45ZTM@72273|Thiotrichales	72273|Thiotrichales	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
k59_353257_1	1121035.AUCH01000018_gene2799	6.48e-95	282.0	COG1373@1|root,COG1373@2|Bacteria,1R4HK@1224|Proteobacteria,2VMYI@28216|Betaproteobacteria	28216|Betaproteobacteria	S	ATPase (AAA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1670318_2	709032.Sulku_0139	3.37e-128	372.0	COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,42NI7@68525|delta/epsilon subdivisions,2YMH9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_24319_1	562981.HMPREF0428_01811	4.18e-76	260.0	COG5412@1|root,COG5412@2|Bacteria,1TQDE@1239|Firmicutes,4HHW1@91061|Bacilli	91061|Bacilli	S	phage tail tape measure protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1610878_1	395494.Galf_1296	5.94e-16	74.7	COG2020@1|root,COG2020@2|Bacteria,1RDC4@1224|Proteobacteria,2WFGW@28216|Betaproteobacteria	28216|Betaproteobacteria	O	isoprenylcysteine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
k59_1032061_1	204773.HEAR1597	8.38e-35	133.0	COG1538@1|root,COG1538@2|Bacteria,1NEZC@1224|Proteobacteria,2VIMD@28216|Betaproteobacteria,473YX@75682|Oxalobacteraceae	28216|Betaproteobacteria	MU	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	czcC	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
k59_1314037_1	1165841.SULAR_04502	1.69e-53	181.0	COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,42NZ4@68525|delta/epsilon subdivisions,2YNNY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	COG2067 Long-chain fatty acid transport protein	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k59_1493885_1	1165841.SULAR_09374	1.64e-155	446.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2YMTZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iIT341.HP0623	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_1032083_1	1249480.B649_04315	3.43e-94	296.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,42MW3@68525|delta/epsilon subdivisions,2YMT6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
k59_1146180_1	90813.JQMT01000001_gene1793	1.99e-26	112.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,45ZPF@72273|Thiotrichales	72273|Thiotrichales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1146196_1	159087.Daro_2036	2.84e-100	301.0	COG4394@1|root,COG4394@2|Bacteria,1MYVF@1224|Proteobacteria,2VHIB@28216|Betaproteobacteria,2KU6H@206389|Rhodocyclales	206389|Rhodocyclales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2331
k59_1032126_3	1537917.JU82_08575	3.68e-33	117.0	28QM5@1|root,2ZD2X@2|Bacteria,1P3YE@1224|Proteobacteria,42WN9@68525|delta/epsilon subdivisions,2YQE1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_561324_1	709032.Sulku_0129	2.65e-106	337.0	COG0439@1|root,COG1984@1|root,COG2049@1|root,COG0439@2|Bacteria,COG1984@2|Bacteria,COG2049@2|Bacteria,1MU4H@1224|Proteobacteria,42P49@68525|delta/epsilon subdivisions,2YNRZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EI	Allophanate hydrolase subunit 1	-	-	6.3.4.6	ko:K01941	ko00220,ko00791,ko01100,map00220,map00791,map01100	-	R00774	RC00378	ko00000,ko00001,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,CT_A_B,CT_C_D
k59_315542_1	1165841.SULAR_09084	1.08e-83	251.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,42MG4@68525|delta/epsilon subdivisions,2YME4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	response regulator	racR	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_315542_2	1165841.SULAR_09089	3.81e-22	94.7	COG0642@1|root,COG2205@2|Bacteria,1QZF7@1224|Proteobacteria,43CIH@68525|delta/epsilon subdivisions,2YTD3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase-like ATPases	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c
k59_1728820_1	1122951.ATUE01000006_gene1501	2.48e-114	345.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,1RN5R@1236|Gammaproteobacteria,3NJJ4@468|Moraxellaceae	1236|Gammaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0043906,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iUTI89_1310.UTI89_C0210	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
k59_1728820_2	717772.THIAE_06985	7.33e-44	155.0	COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,1RPVJ@1236|Gammaproteobacteria,460J2@72273|Thiotrichales	72273|Thiotrichales	F	Belongs to the dGTPase family. Type 2 subfamily	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
k59_906648_1	563040.Saut_1306	7.32e-32	118.0	COG2215@1|root,COG2215@2|Bacteria,1Q5AP@1224|Proteobacteria,42R81@68525|delta/epsilon subdivisions,2YP06@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the NiCoT transporter (TC 2.A.52) family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_906648_2	563040.Saut_1310	6.6e-84	272.0	COG1251@1|root,COG1740@1|root,COG1251@2|Bacteria,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,42PSD@68525|delta/epsilon subdivisions,2YNBA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	hydrogenase (NiFe) small subunit HydA	-	-	1.12.5.1	ko:K05927	-	-	-	-	ko00000,ko01000	-	-	-	Fer2_BFD,NiFe_hyd_SSU_C,Oxidored_q6,Pyr_redox_2
k59_1084514_2	1033739.CAEU01000018_gene2307	2.07e-08	57.8	COG0756@1|root,COG0756@2|Bacteria,1V6HX@1239|Firmicutes,4HIZ3@91061|Bacilli,26HIQ@186818|Planococcaceae	91061|Bacilli	F	dUTPase	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
k59_1084514_6	1218352.B597_019395	1.68e-14	72.8	COG3728@1|root,COG3728@2|Bacteria,1N73T@1224|Proteobacteria,1SDUM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Terminase small subunit	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_2
k59_678243_1	709032.Sulku_0244	1.06e-95	287.0	COG1344@1|root,COG1344@2|Bacteria,1P7ZB@1224|Proteobacteria,42QS1@68525|delta/epsilon subdivisions,2YNAV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	flaC	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
k59_906656_1	1537917.JU82_06900	3.56e-76	249.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,42NHZ@68525|delta/epsilon subdivisions,2YMTE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	5-methyltetrahydrofolate--homocysteine methyltransferase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
k59_1314135_1	709032.Sulku_1154	6.96e-56	189.0	COG4773@1|root,COG4773@2|Bacteria,1R8BS@1224|Proteobacteria,42M7T@68525|delta/epsilon subdivisions,2YS9H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	PFAM outer membrane porin	-	-	-	-	-	-	-	-	-	-	-	-	OprD
k59_561363_1	1499680.CCFE01000025_gene3235	1.36e-09	60.5	COG1396@1|root,COG1396@2|Bacteria,1UYX5@1239|Firmicutes,4HF70@91061|Bacilli,1ZD6X@1386|Bacillus	91061|Bacilli	K	Helix-turn-helix domain	-	-	-	ko:K20342,ko:K20391	ko02024,map02024	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_19,HTH_3
k59_81293_1	159087.Daro_0938	4.39e-116	342.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,2VH9Q@28216|Betaproteobacteria,2KUWH@206389|Rhodocyclales	206389|Rhodocyclales	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
k59_261161_1	1345695.CLSA_c38280	1.99e-10	68.6	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,24EYC@186801|Clostridia,36GXX@31979|Clostridiaceae	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
k59_436750_1	1537917.JU82_07845	1.66e-128	395.0	COG0755@1|root,COG1333@1|root,COG0755@2|Bacteria,COG1333@2|Bacteria,1RG0A@1224|Proteobacteria,42N37@68525|delta/epsilon subdivisions,2YMXW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Cytochrome c biogenesis protein	ccsBA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
k59_1558477_1	1249480.B649_08845	3.56e-53	176.0	COG3064@1|root,COG3064@2|Bacteria	2|Bacteria	M	translation initiation factor activity	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	Peptidase_M56
k59_1610990_1	871585.BDGL_003001	3.04e-76	244.0	COG1123@1|root,COG1123@2|Bacteria,1R0HJ@1224|Proteobacteria,1STCK@1236|Gammaproteobacteria,3NQHX@468|Moraxellaceae	1236|Gammaproteobacteria	P	Protein of unknown function (DUF4435)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21,DUF4435
k59_968956_1	438753.AZC_3598	1.41e-12	67.0	COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1QT52@1224|Proteobacteria,2TVNI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Toprim-like	-	-	3.6.4.12	ko:K17680	-	-	-	-	ko00000,ko01000,ko03029	-	-	-	DnaB_C,Toprim_2
k59_561404_1	709032.Sulku_1155	1.22e-116	339.0	COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,42QWE@68525|delta/epsilon subdivisions,2YNG3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	ABC transporter, periplasmic molybdate-binding protein	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
k59_561404_2	709032.Sulku_0450	4.91e-16	78.2	COG4773@1|root,COG4773@2|Bacteria,1QZ1U@1224|Proteobacteria,42PHE@68525|delta/epsilon subdivisions,2YN5J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Receptor	-	-	-	-	-	-	-	-	-	-	-	-	OprD
k59_1146304_1	1123517.JOMR01000001_gene699	1.06e-60	213.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RPIP@1236|Gammaproteobacteria,46225@72273|Thiotrichales	72273|Thiotrichales	S	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_147307_1	1249480.B649_10240	1.64e-69	218.0	COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,42N17@68525|delta/epsilon subdivisions,2YMV6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
k59_724532_1	159087.Daro_1078	1.13e-96	282.0	COG2050@1|root,COG2050@2|Bacteria,1RBPE@1224|Proteobacteria,2VQZE@28216|Betaproteobacteria,2KW2S@206389|Rhodocyclales	206389|Rhodocyclales	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
k59_616847_1	857087.Metme_1535	4.05e-12	64.7	COG0115@1|root,COG0115@2|Bacteria,1MVAT@1224|Proteobacteria,1RPU0@1236|Gammaproteobacteria,1XE1X@135618|Methylococcales	135618|Methylococcales	EH	PFAM Aminotransferase, class IV	-	-	2.6.1.21	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	-	R01148,R01582,R02459,R02851,R02924,R05053	RC00006,RC00008,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4
k59_616847_2	1266925.JHVX01000014_gene1575	1.73e-39	142.0	COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,2VH46@28216|Betaproteobacteria,3721U@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Belongs to the peptidase S11 family	dacC	-	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
k59_1314212_1	159087.Daro_3725	1.37e-118	357.0	COG0699@1|root,COG0699@2|Bacteria,1MXBK@1224|Proteobacteria,2VKA1@28216|Betaproteobacteria,2KUHM@206389|Rhodocyclales	206389|Rhodocyclales	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
k59_1728907_1	1165841.SULAR_02683	9.59e-108	318.0	2BVW3@1|root,2Z7TB@2|Bacteria,1MY60@1224|Proteobacteria,42QE2@68525|delta/epsilon subdivisions,2YNKM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	5'-nucleotidase	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5-nucleotidase
k59_968990_1	56780.SYN_02290	1.17e-67	223.0	COG3941@1|root,COG3941@2|Bacteria,1RC0N@1224|Proteobacteria	1224|Proteobacteria	S	tape measure	-	-	-	-	-	-	-	-	-	-	-	-	PhageMin_Tail
k59_1376864_1	1235788.C802_03641	4.72e-28	117.0	COG0612@1|root,COG0612@2|Bacteria,4NFY0@976|Bacteroidetes,2FMCE@200643|Bacteroidia,4ANGJ@815|Bacteroidaceae	976|Bacteroidetes	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_724546_1	159087.Daro_1739	1.95e-152	452.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,2VI2G@28216|Betaproteobacteria,2KV4M@206389|Rhodocyclales	206389|Rhodocyclales	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,GlnD_UR_UTase,HD,NTP_transf_2
k59_202779_1	1304883.KI912532_gene1073	5.17e-89	274.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VJGE@28216|Betaproteobacteria,2KV0D@206389|Rhodocyclales	206389|Rhodocyclales	T	His Kinase A (phosphoacceptor) domain	hoxJ	-	2.7.13.3	ko:K19661	ko02020,map02020	M00772	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_4
k59_1494024_1	1165841.SULAR_07770	1.64e-79	253.0	COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,42P71@68525|delta/epsilon subdivisions,2YNAA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Phospholipid glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5,Acyltransferase
k59_147331_1	1165841.SULAR_09214	2.05e-65	203.0	COG1585@1|root,COG1585@2|Bacteria,1QAJG@1224|Proteobacteria,43AB2@68525|delta/epsilon subdivisions,2YQRB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	OU	Membrane protein implicated in regulation of membrane protease activity	-	-	-	ko:K07340	-	-	-	-	ko00000	-	-	-	NfeD
k59_147331_2	1165841.SULAR_09219	2.61e-07	51.2	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,42NX0@68525|delta/epsilon subdivisions,2YMHX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Membrane protease subunits	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_1787158_1	709032.Sulku_0788	1.17e-204	574.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,42MAH@68525|delta/epsilon subdivisions,2YMZK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
k59_1787158_2	1537917.JU82_04810	2.07e-35	131.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,42M2M@68525|delta/epsilon subdivisions,2YMS3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
k59_202789_2	72019.SARC_03659T0	1.79e-07	50.8	COG0432@1|root,KOG3267@2759|Eukaryota,38FBH@33154|Opisthokonta	33154|Opisthokonta	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
k59_24453_1	1249480.B649_05220	2.43e-130	382.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42N0C@68525|delta/epsilon subdivisions,2YMDS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the aldehyde dehydrogenase family	aldB	-	-	ko:K00138	ko00010,ko00620,ko01100,ko01110,ko01120,map00010,map00620,map01100,map01110,map01120	-	R00711	RC00047	ko00000,ko00001,ko01000	-	-	-	Aldedh
k59_202801_1	1249480.B649_07595	9.99e-46	161.0	COG1538@1|root,COG1538@2|Bacteria,1QWWG@1224|Proteobacteria,42PH5@68525|delta/epsilon subdivisions,2YMHH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_969042_1	1453501.JELR01000001_gene2933	7.03e-24	99.8	COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,1RMSQ@1236|Gammaproteobacteria,4641J@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	COG3118 Thioredoxin domain-containing protein	ybbN	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0008150,GO:0008152,GO:0009987,GO:0015035,GO:0015036,GO:0016491,GO:0016667,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0061077	-	ko:K03671,ko:K05838	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
k59_969042_2	998674.ATTE01000001_gene2814	0.000529	44.3	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,1RNW3@1236|Gammaproteobacteria,45ZW4@72273|Thiotrichales	72273|Thiotrichales	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
k59_1265527_1	159087.Daro_0787	3.89e-89	279.0	COG2199@1|root,COG3706@2|Bacteria,1MXAW@1224|Proteobacteria,2VK79@28216|Betaproteobacteria,2KUEF@206389|Rhodocyclales	206389|Rhodocyclales	T	GGDEF domain	-	-	2.7.7.65	ko:K13590	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF
k59_1314284_1	709032.Sulku_1956	1.7e-80	255.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42N03@68525|delta/epsilon subdivisions,2YNMG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	PFAM Methyl-accepting chemotaxis protein (MCP) signaling domain	-	-	-	ko:K03406,ko:K05875	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,MCPsignal
k59_1199939_1	1279017.AQYJ01000029_gene3823	1.79e-54	185.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,1RN93@1236|Gammaproteobacteria,464G4@72275|Alteromonadaceae	1236|Gammaproteobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ASL_C,Lyase_1
k59_678414_1	1437824.BN940_02271	1.62e-64	209.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,2VIS0@28216|Betaproteobacteria,3T35Z@506|Alcaligenaceae	28216|Betaproteobacteria	S	Peptidase dimerisation domain	-	-	3.5.1.32	ko:K01451	ko00360,map00360	-	R01424	RC00096,RC00162	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
k59_261276_1	159087.Daro_0638	2.38e-159	455.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,2VHPE@28216|Betaproteobacteria,2KUZY@206389|Rhodocyclales	206389|Rhodocyclales	U	type II secretion system protein	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
k59_1314307_1	1166016.W5S_3458	1.16e-50	170.0	COG0730@1|root,COG0730@2|Bacteria,1MVA4@1224|Proteobacteria,1RS8K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	TauE
k59_1314309_1	1304883.KI912532_gene1288	6.93e-92	281.0	COG0840@1|root,COG0840@2|Bacteria,1R5W9@1224|Proteobacteria,2VKQP@28216|Betaproteobacteria,2KUE3@206389|Rhodocyclales	206389|Rhodocyclales	NT	Methyl-accepting chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	CZB,MCPsignal
k59_499831_1	395494.Galf_1879	2.79e-45	167.0	COG3850@1|root,COG5001@1|root,COG3850@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_3,PAS_4,PAS_9,SBP_bac_3,dCache_1
k59_1852208_2	1123514.KB905899_gene1387	2.47e-26	102.0	COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,1S5X6@1236|Gammaproteobacteria,460RV@72273|Thiotrichales	72273|Thiotrichales	T	Low molecular weight phosphotyrosine protein phosphatase	yfkJ	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
k59_1558645_1	929506.CbC4_0508	2.66e-77	243.0	COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,2491V@186801|Clostridia,36ECU@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	czcD	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
k59_678457_1	709032.Sulku_0635	3.39e-97	297.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42P4R@68525|delta/epsilon subdivisions,2YM92@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	DUF3365,MCPsignal
k59_617009_1	1537917.JU82_08305	2.7e-174	496.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,42MK9@68525|delta/epsilon subdivisions,2YNM1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	ATPase related to phosphate starvation-inducible protein PhoH	phoH	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
k59_1146506_2	709032.Sulku_0318	4.44e-37	128.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,42SJW@68525|delta/epsilon subdivisions,2YNXS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	sigma 54 modulation protein ribosomal protein S30EA	raiA	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
k59_617035_1	709032.Sulku_1959	2.73e-96	293.0	COG3437@1|root,COG3437@2|Bacteria,1QYD6@1224|Proteobacteria,43CBH@68525|delta/epsilon subdivisions,2YTB6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	cheY-homologous receiver domain	-	-	3.1.1.61,3.5.1.44	ko:K03412,ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	Response_reg
k59_499925_1	247634.GPB2148_315	4.88e-11	68.6	COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,1RQW0@1236|Gammaproteobacteria,1J885@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
k59_1729070_1	395494.Galf_0809	3.23e-107	319.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,2VI6I@28216|Betaproteobacteria,44V9T@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817	2.3.1.179	ko:K00646,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_561658_1	929558.SMGD1_0382	3.02e-11	62.8	COG1352@1|root,COG1352@2|Bacteria,1MVP3@1224|Proteobacteria,42SZX@68525|delta/epsilon subdivisions,2YTRV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Methyltransferase, chemotaxis proteins	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR
k59_1036176_1	1121035.AUCH01000005_gene167	6.52e-21	84.3	COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,2VU2J@28216|Betaproteobacteria,2KWWG@206389|Rhodocyclales	206389|Rhodocyclales	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	grxC	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
k59_1036176_2	159087.Daro_0611	2.98e-76	229.0	COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,2VU3D@28216|Betaproteobacteria,2KWVI@206389|Rhodocyclales	206389|Rhodocyclales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_1202730_1	326298.Suden_1744	3.47e-18	80.5	2AVG9@1|root,31M8F@2|Bacteria,1QJ39@1224|Proteobacteria,42W1H@68525|delta/epsilon subdivisions,2YQB8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1087445_1	1537917.JU82_07250	6.02e-108	323.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,42M04@68525|delta/epsilon subdivisions,2YMAR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
k59_1087445_2	1537917.JU82_07245	1.24e-33	128.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42M01@68525|delta/epsilon subdivisions,2YMF7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	ABC transporter	msbA	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
k59_1036199_1	358220.C380_16060	1.16e-117	358.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,2VIAU@28216|Betaproteobacteria,4AARJ@80864|Comamonadaceae	28216|Betaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_1379728_1	709032.Sulku_1273	2.34e-58	194.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,42N30@68525|delta/epsilon subdivisions,2YMCR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the pyruvate kinase family	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK
k59_1379728_2	709032.Sulku_1274	3.01e-48	164.0	COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,42N4P@68525|delta/epsilon subdivisions,2YMDF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
k59_503017_1	381764.Fnod_1277	1.14e-14	83.2	COG0642@1|root,COG3829@1|root,COG2205@2|Bacteria,COG3829@2|Bacteria,2GCUP@200918|Thermotogae	200918|Thermotogae	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,HisKA_7TM,Hpt,PAS_4,PAS_9,Response_reg
k59_503017_2	929558.SMGD1_0375	3.7e-85	257.0	COG1192@1|root,COG1192@2|Bacteria,1R7XC@1224|Proteobacteria	1224|Proteobacteria	D	NUBPL iron-transfer P-loop NTPase	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
k59_1562128_1	1123326.JFBL01000002_gene1587	1.45e-61	210.0	COG3437@1|root,COG4564@1|root,COG3437@2|Bacteria,COG4564@2|Bacteria,1QUN9@1224|Proteobacteria,42PB6@68525|delta/epsilon subdivisions,2YTKF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,PAS_9,Response_reg
k59_83901_1	1537917.JU82_10615	3.42e-184	523.0	COG1032@1|root,COG1032@2|Bacteria,1Q5NG@1224|Proteobacteria,42N2D@68525|delta/epsilon subdivisions,2YNAR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4080,Radical_SAM
k59_760255_1	709032.Sulku_0810	5e-20	84.7	COG2161@1|root,COG2161@2|Bacteria	2|Bacteria	D	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
k59_760255_2	709032.Sulku_0811	1.66e-18	79.3	COG3668@1|root,COG3668@2|Bacteria,1N2I9@1224|Proteobacteria,42W6G@68525|delta/epsilon subdivisions,2YQDJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
k59_57425_1	1132855.KB913035_gene584	3.35e-64	207.0	COG1208@1|root,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,2VNAZ@28216|Betaproteobacteria,2KKFN@206350|Nitrosomonadales	206350|Nitrosomonadales	JM	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
k59_760376_1	159087.Daro_0402	1.9e-82	263.0	COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MWDY@1224|Proteobacteria,2VK7T@28216|Betaproteobacteria,2KUKS@206389|Rhodocyclales	206389|Rhodocyclales	IQ	Phosphate acyltransferases	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase
k59_116566_1	990073.ATHU01000001_gene1036	9.5e-93	286.0	COG2244@1|root,COG2244@2|Bacteria,1R9XE@1224|Proteobacteria,42X85@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Polysaccharide biosynthesis protein	-	-	-	ko:K03328	-	-	-	-	ko00000	2.A.66.2	-	-	Polysacc_synt,Polysacc_synt_C
k59_116596_1	768671.ThimaDRAFT_0992	5.11e-11	62.0	COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,1S3PG@1236|Gammaproteobacteria,1WWUP@135613|Chromatiales	135613|Chromatiales	V	PFAM N-acetylmuramoyl-L-alanine amidase family 2	-	-	3.5.1.28	ko:K03806	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	Amidase_2
k59_116596_2	159087.Daro_0662	4.15e-55	184.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,2KUM4@206389|Rhodocyclales	206389|Rhodocyclales	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	pilR	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_116621_1	709032.Sulku_1214	7.03e-33	121.0	2BSET@1|root,32MGT@2|Bacteria,1Q39R@1224|Proteobacteria,42WZN@68525|delta/epsilon subdivisions,2YQU4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
k59_760469_1	871968.DESME_08415	3.5e-63	209.0	COG1322@1|root,COG1322@2|Bacteria,1TPWI@1239|Firmicutes,24CA4@186801|Clostridia,26006@186807|Peptococcaceae	186801|Clostridia	S	PFAM RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
k59_116754_2	1172190.M947_09490	2.58e-29	107.0	COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,42TWY@68525|delta/epsilon subdivisions,2YPX1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
k59_760750_1	159087.Daro_0962	3.42e-141	411.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,2VHWX@28216|Betaproteobacteria,2KUBM@206389|Rhodocyclales	206389|Rhodocyclales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k59_760934_1	223926.28807858	6.48e-51	173.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,1RPQ7@1236|Gammaproteobacteria,1XSBF@135623|Vibrionales	135623|Vibrionales	I	Glycerol-3-phosphate dehydrogenase	gpsA	GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
k59_57954_1	1355374.JARU01000004_gene1676	2.33e-43	152.0	COG0745@1|root,COG0745@2|Bacteria,1QUJR@1224|Proteobacteria,42NQS@68525|delta/epsilon subdivisions,2YP2K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_58156_1	522306.CAP2UW1_0588	2.72e-33	122.0	COG2823@1|root,COG2823@2|Bacteria,1MUZ2@1224|Proteobacteria,2VQIS@28216|Betaproteobacteria,1KQ4B@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	General function prediction only	-	-	-	-	-	-	-	-	-	-	-	-	BON
k59_58156_2	1304883.KI912532_gene345	4.83e-83	248.0	COG0279@1|root,COG0279@2|Bacteria,1NJ8X@1224|Proteobacteria,2VN12@28216|Betaproteobacteria,2KVWJ@206389|Rhodocyclales	206389|Rhodocyclales	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
k59_761574_1	1537917.JU82_03225	2.99e-46	164.0	COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2YMB9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	chemotaxis protein	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k59_761864_1	395494.Galf_1644	5.53e-24	101.0	COG1882@1|root,COG1882@2|Bacteria,1MWBF@1224|Proteobacteria	1224|Proteobacteria	C	Formate acetyltransferase	-	-	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
k59_58508_1	1336249.JADW01000002_gene4316	8.84e-06	50.1	COG3030@1|root,COG3030@2|Bacteria,1MZJJ@1224|Proteobacteria,2UF72@28211|Alphaproteobacteria,4BCF8@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein affecting phage T7 exclusion by the F plasmid	fxsA	-	-	ko:K07113	-	-	-	-	ko00000	-	-	-	FxsA
k59_58508_2	666681.M301_0061	4.19e-16	80.1	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,2VI8I@28216|Betaproteobacteria,2KKIB@206350|Nitrosomonadales	206350|Nitrosomonadales	CO	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_2,Thioredoxin_7
k59_58542_1	159087.Daro_3625	1.75e-32	121.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,2VHHG@28216|Betaproteobacteria,2KUIY@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k59_58542_2	159087.Daro_3626	1.79e-54	186.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,2VHNX@28216|Betaproteobacteria,2KV91@206389|Rhodocyclales	28216|Betaproteobacteria	H	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	cbbT	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
k59_762004_1	1380763.BG53_01815	4.03e-37	142.0	COG0438@1|root,COG0438@2|Bacteria,1TQ8U@1239|Firmicutes,4HBRW@91061|Bacilli,26REH@186822|Paenibacillaceae	91061|Bacilli	M	Domain of unknown function (DUF3492)	-	-	2.4.1.52	ko:K00712,ko:K21011	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT4	-	DUF3492,Glyco_trans_A_1,Glycos_transf_1
k59_762379_1	159087.Daro_0526	9.94e-78	251.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,2VH74@28216|Betaproteobacteria,2KVA2@206389|Rhodocyclales	206389|Rhodocyclales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_762436_1	709032.Sulku_2072	3.05e-15	72.4	COG3751@1|root,COG3751@2|Bacteria,1Q4MK@1224|Proteobacteria,42ZFP@68525|delta/epsilon subdivisions,2YRNS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Prolyl 4-hydroxylase alpha subunit homologues.	-	-	-	ko:K07394	-	-	-	-	ko00000	-	-	-	2OG-FeII_Oxy_3
k59_762436_2	1537917.JU82_08400	3.14e-72	218.0	COG0848@1|root,COG0848@2|Bacteria,1N9DN@1224|Proteobacteria,42V0H@68525|delta/epsilon subdivisions,2YQ7R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	biopolymer transport protein	exbD	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
k59_762857_1	709032.Sulku_0831	1.61e-55	189.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2YMXZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	ABC transporter, ATP-binding protein	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
k59_762923_1	159087.Daro_3366	4.14e-108	322.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,2VI46@28216|Betaproteobacteria,2KVJW@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
k59_763150_1	709032.Sulku_0646	4.44e-06	46.6	2994D@1|root,2ZW7V@2|Bacteria,1Q2D1@1224|Proteobacteria,42VGB@68525|delta/epsilon subdivisions,2YQM6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_763150_2	709032.Sulku_0647	2.29e-113	342.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42S84@68525|delta/epsilon subdivisions,2YPD4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_3
k59_529433_2	1132855.KB913035_gene601	6.55e-37	129.0	COG1905@1|root,COG1905@2|Bacteria,1RHBU@1224|Proteobacteria,2VSVZ@28216|Betaproteobacteria,2KMRQ@206350|Nitrosomonadales	206350|Nitrosomonadales	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	-	-	-	ko:K00127	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	2Fe-2S_thioredx
k59_529437_1	1304883.KI912532_gene844	6.95e-87	266.0	28HWK@1|root,2Z82H@2|Bacteria,1MVDT@1224|Proteobacteria,2VM8W@28216|Betaproteobacteria,2KV5A@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF1615)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1615
k59_1233742_1	314345.SPV1_00240	2.69e-38	142.0	COG0438@1|root,COG0438@2|Bacteria,1N0DG@1224|Proteobacteria	1224|Proteobacteria	M	Glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
k59_1762033_1	387093.SUN_1735	6.87e-23	102.0	COG1215@1|root,COG1216@1|root,COG1215@2|Bacteria,COG1216@2|Bacteria,1MZSD@1224|Proteobacteria,42Q1D@68525|delta/epsilon subdivisions,2YNN5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Glycosyltransferase like family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
k59_529455_1	1537917.JU82_09315	9.34e-121	356.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42MGY@68525|delta/epsilon subdivisions,2YN2P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Glutamate synthase	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2,Pyr_redox_3
k59_1527402_1	748247.AZKH_4037	2.29e-110	326.0	COG3005@1|root,COG3005@2|Bacteria,1MV9J@1224|Proteobacteria,2WFG5@28216|Betaproteobacteria,2M048@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome c3	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
k59_1116106_1	159087.Daro_3400	1.59e-19	82.4	COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,2VRKR@28216|Betaproteobacteria,2KWBN@206389|Rhodocyclales	206389|Rhodocyclales	Q	ABC-type transport system involved in resistance to organic solvents, periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
k59_1116106_2	159087.Daro_3401	7.38e-87	261.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,2VI5T@28216|Betaproteobacteria,2KUIX@206389|Rhodocyclales	206389|Rhodocyclales	Q	COG0767 ABC-type transport system involved in resistance to organic solvents, permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
k59_1644547_1	159087.Daro_2782	6.22e-180	506.0	COG2207@1|root,COG2207@2|Bacteria,1R81X@1224|Proteobacteria,2VPTC@28216|Betaproteobacteria,2KXZE@206389|Rhodocyclales	206389|Rhodocyclales	K	AraC-binding-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding_2,HTH_18
k59_1233763_1	1370122.JHXQ01000019_gene200	3.24e-46	170.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2TQR7@28211|Alphaproteobacteria,4BAAU@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Sensory methylation accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,PAS_3,PAS_4,PAS_9
k59_1762047_2	1537917.JU82_01365	9.86e-17	81.3	COG1940@1|root,COG1940@2|Bacteria,1MU94@1224|Proteobacteria,42S50@68525|delta/epsilon subdivisions,2YP7Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	GK	COGs COG1940 Transcriptional regulator sugar kinase	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
k59_587922_1	159087.Daro_2398	2.33e-93	289.0	COG3206@1|root,COG3206@2|Bacteria,1MVBX@1224|Proteobacteria,2VMDA@28216|Betaproteobacteria,2KUAM@206389|Rhodocyclales	206389|Rhodocyclales	M	Polysaccharide chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
k59_587922_2	1304883.KI912532_gene2906	0.000536	42.0	COG0489@1|root,COG0489@2|Bacteria,1MVI9@1224|Proteobacteria,2VJEB@28216|Betaproteobacteria,2KUMI@206389|Rhodocyclales	206389|Rhodocyclales	D	COG0489 ATPases involved in chromosome partitioning	-	-	2.7.10.1	ko:K08252	-	-	-	-	ko00000,ko01000	-	-	-	AAA_31
k59_59638_1	709032.Sulku_2169	4.73e-128	369.0	COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,42N17@68525|delta/epsilon subdivisions,2YMV6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
k59_1175118_1	1249480.B649_06005	1.79e-100	315.0	COG2202@1|root,COG2461@1|root,COG5001@1|root,COG2202@2|Bacteria,COG2461@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YN16@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	GGDEF EAL family protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_9
k59_352995_1	159087.Daro_0934	2.59e-80	239.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,2VR52@28216|Betaproteobacteria,2KWB1@206389|Rhodocyclales	206389|Rhodocyclales	K	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
k59_352995_2	159087.Daro_0935	9.99e-22	88.2	COG2913@1|root,COG2913@2|Bacteria,1N6YW@1224|Proteobacteria,2VRC6@28216|Betaproteobacteria,2KX54@206389|Rhodocyclales	206389|Rhodocyclales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamE	-	-	ko:K06186	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	SmpA_OmlA
k59_1820989_1	159087.Daro_3346	9.24e-39	131.0	COG4654@1|root,COG4654@2|Bacteria,1N6UN@1224|Proteobacteria,2VW1Y@28216|Betaproteobacteria	28216|Betaproteobacteria	C	PFAM Cytochrome c, class I	cyt	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C
k59_1820989_2	159087.Daro_3344	3.67e-23	97.4	COG0845@1|root,COG0845@2|Bacteria,1NQZ0@1224|Proteobacteria,2VJAC@28216|Betaproteobacteria,2KUKR@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
k59_1301_1	709032.Sulku_0753	3.91e-143	409.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,42M8S@68525|delta/epsilon subdivisions,2YNN2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
k59_529509_1	159087.Daro_2739	3.99e-49	161.0	2E94J@1|root,333DE@2|Bacteria,1N7Q9@1224|Proteobacteria,2VXHD@28216|Betaproteobacteria,2KYZW@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_353005_1	553385.JEMF01000030_gene2524	3.48e-111	331.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,1RNZZ@1236|Gammaproteobacteria,1XIE0@135619|Oceanospirillales	135619|Oceanospirillales	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
k59_294392_1	709032.Sulku_0145	8.47e-65	206.0	COG0775@1|root,COG0775@2|Bacteria,1QSEF@1224|Proteobacteria,42X56@68525|delta/epsilon subdivisions,2YQPV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	-	-	-	-	-	-	-	-	-	-	-	-	PNP_UDP_1
k59_1586057_1	640081.Dsui_2765	7.45e-59	189.0	COG1285@1|root,COG1285@2|Bacteria,1MURJ@1224|Proteobacteria,2WFS8@28216|Betaproteobacteria,2KZVJ@206389|Rhodocyclales	206389|Rhodocyclales	S	MgtC family	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
k59_1468355_1	349124.Hhal_0311	1.1e-45	167.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	HATPase_c,HisKA,Reg_prop,Response_reg,Y_Y_Y
k59_1703426_1	1163617.SCD_n00481	8.95e-89	279.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,2VHE1@28216|Betaproteobacteria	28216|Betaproteobacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
k59_118391_1	1442598.JABW01000006_gene672	1.72e-56	187.0	COG0671@1|root,COG0671@2|Bacteria,1QV0A@1224|Proteobacteria,43BVB@68525|delta/epsilon subdivisions,2YTA9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Acid phosphatase homologues	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
k59_470705_1	1249480.B649_09260	1.33e-45	154.0	COG1305@1|root,COG1305@2|Bacteria,1MVMI@1224|Proteobacteria,42PJK@68525|delta/epsilon subdivisions,2YNSY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Bacterial transglutaminase-like N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
k59_470705_2	709032.Sulku_1756	4.08e-73	241.0	COG2307@1|root,COG2308@1|root,COG2307@2|Bacteria,COG2308@2|Bacteria,1MX5P@1224|Proteobacteria,42NB9@68525|delta/epsilon subdivisions,2YNN4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E,CP_ATPgrasp_2
k59_1409614_1	159087.Daro_0866	1e-48	179.0	COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,2VHX1@28216|Betaproteobacteria,2KUPN@206389|Rhodocyclales	206389|Rhodocyclales	NU	COG3170 Tfp pilus assembly protein FimV	-	-	-	ko:K08086	-	-	-	-	ko00000	-	-	-	LysM
k59_1644632_1	749222.Nitsa_0709	2.99e-13	68.6	COG0569@1|root,COG0569@2|Bacteria,1QZMU@1224|Proteobacteria,43EBB@68525|delta/epsilon subdivisions,2YTDK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	TrkA-N domain	-	-	-	-	-	-	-	-	-	-	-	-	TrkA_C,TrkA_N
k59_1644632_2	1165841.SULAR_04863	1.49e-91	275.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,42NQB@68525|delta/epsilon subdivisions,2YMSA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	iIT341.HP0961	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
k59_1175202_1	358220.C380_03475	1.82e-16	76.3	COG0765@1|root,COG0765@2|Bacteria,1MUVX@1224|Proteobacteria,2VJ8A@28216|Betaproteobacteria,4ACFJ@80864|Comamonadaceae	28216|Betaproteobacteria	P	polar amino acid ABC transporter, inner membrane subunit	gltJ	-	-	ko:K02029,ko:K10003	ko02010,ko02020,map02010,map02020	M00230,M00236	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.19,3.A.1.3.4	-	-	BPD_transp_1
k59_1175202_2	1276756.AUEX01000016_gene1913	4.83e-81	244.0	COG0765@1|root,COG0765@2|Bacteria,1MV3I@1224|Proteobacteria,2VIQB@28216|Betaproteobacteria,4AAVP@80864|Comamonadaceae	28216|Betaproteobacteria	P	polar amino acid ABC transporter, inner membrane subunit	gltK	-	-	ko:K10002	ko02010,ko02020,map02010,map02020	M00230	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.19,3.A.1.3.4	-	-	BPD_transp_1
k59_470741_1	317025.Tcr_0182	6.17e-100	298.0	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,1RN2H@1236|Gammaproteobacteria,45ZYE@72273|Thiotrichales	72273|Thiotrichales	D	Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system	ttcA	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
k59_118429_1	159087.Daro_2936	1.32e-96	305.0	COG2010@1|root,COG2010@2|Bacteria,1R58S@1224|Proteobacteria,2VJWF@28216|Betaproteobacteria,2KY3E@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1233902_1	443143.GM18_0106	0.000142	51.6	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,42R8H@68525|delta/epsilon subdivisions,2WMWF@28221|Deltaproteobacteria,43T80@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	PEGA,Plug,TonB_dep_Rec
k59_647134_1	159087.Daro_0544	7.43e-55	189.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,2VH2J@28216|Betaproteobacteria,2KV8K@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
k59_647137_1	159087.Daro_0473	9.52e-126	384.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2VIJE@28216|Betaproteobacteria,2KUQF@206389|Rhodocyclales	206389|Rhodocyclales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	-
k59_1527586_1	1454004.AW11_00611	5.44e-107	322.0	COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,2VP40@28216|Betaproteobacteria	28216|Betaproteobacteria	M	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_1527586_2	1454004.AW11_00612	1.07e-06	50.1	COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,2VKX2@28216|Betaproteobacteria	28216|Betaproteobacteria	M	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_1292597_1	159087.Daro_3457	5.19e-46	160.0	COG1024@1|root,COG1024@2|Bacteria,1NYF6@1224|Proteobacteria,2VPXB@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Enoyl-CoA hydratase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1292597_2	987059.RBXJA2T_18834	4.42e-36	133.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,2VH1F@28216|Betaproteobacteria,1KKWQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	metal-dependent phosphohydrolase HD sub domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
k59_764003_1	1163407.UU7_03162	2.72e-09	55.8	COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,1S3YC@1236|Gammaproteobacteria,1X63W@135614|Xanthomonadales	135614|Xanthomonadales	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
k59_764003_2	948565.AFFP02000007_gene369	7.16e-24	99.8	COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,1RNHQ@1236|Gammaproteobacteria,1Y6Z6@135625|Pasteurellales	135625|Pasteurellales	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	dnaQ	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_764009_1	1163617.SCD_n02480	3.39e-10	60.5	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,2VGZP@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
k59_764009_2	323848.Nmul_A2488	1.55e-35	131.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,2VH0S@28216|Betaproteobacteria,372PE@32003|Nitrosomonadales	28216|Betaproteobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
k59_1468422_1	159087.Daro_4143	2.88e-130	374.0	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,2VHWH@28216|Betaproteobacteria,2KU6Q@206389|Rhodocyclales	206389|Rhodocyclales	J	Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system	ttcA	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
k59_294500_1	387093.SUN_0187	1.05e-70	238.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,42NKH@68525|delta/epsilon subdivisions,2YMVS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the helicase family. UvrD subfamily	addA	-	3.1.11.5	ko:K03582	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C
k59_1703514_1	946483.Cenrod_2395	5.09e-21	95.5	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2VJ72@28216|Betaproteobacteria,4ABWU@80864|Comamonadaceae	28216|Betaproteobacteria	T	Adenylate cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
k59_1644695_1	1123514.KB905899_gene1717	7.05e-27	107.0	COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,1RNTF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	N	With MotB forms the ion channels that couple flagellar rotation to proton sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine	motA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
k59_1644695_2	1168067.JAGP01000001_gene321	1.58e-19	82.8	COG2608@1|root,COG2608@2|Bacteria,1N81B@1224|Proteobacteria,1SD0H@1236|Gammaproteobacteria,46190@72273|Thiotrichales	72273|Thiotrichales	P	Heavy-metal-associated domain	-	-	-	ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
k59_1644695_3	1123053.AUDG01000044_gene2058	4.57e-10	57.8	COG2200@1|root,COG2200@2|Bacteria,1N299@1224|Proteobacteria	1224|Proteobacteria	T	EAL domain	yfgF	GO:0000302,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008081,GO:0008150,GO:0009628,GO:0009636,GO:0009987,GO:0010035,GO:0016020,GO:0016021,GO:0016787,GO:0016788,GO:0031224,GO:0033554,GO:0034059,GO:0034599,GO:0034614,GO:0035690,GO:0036293,GO:0036294,GO:0042221,GO:0042493,GO:0042542,GO:0042578,GO:0043900,GO:0044425,GO:0044464,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070301,GO:0070482,GO:0070887,GO:0071111,GO:0071236,GO:0071453,GO:0071454,GO:0071944,GO:0097237,GO:1900190,GO:1901700,GO:1901701	-	-	-	-	-	-	-	-	-	-	EAL,MASE1
k59_1233938_2	243231.GSU0618	6.02e-15	74.7	COG3303@1|root,COG3303@2|Bacteria,1RG2D@1224|Proteobacteria	1224|Proteobacteria	P	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
k59_412020_1	709032.Sulku_0305	3.31e-93	294.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2YMNT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_412020_2	1249480.B649_01335	7.6e-15	71.6	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,42RV8@68525|delta/epsilon subdivisions,2YPC0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
k59_781456_1	1537917.JU82_05300	8.33e-27	103.0	COG2928@1|root,COG2928@2|Bacteria,1PKH9@1224|Proteobacteria,42XVN@68525|delta/epsilon subdivisions,2YQSF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
k59_781456_2	1249480.B649_08895	7.27e-79	253.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,42MUY@68525|delta/epsilon subdivisions,2YMZF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	PFAM peptidase M3A and M3B thimet oligopeptidase F	prlC	-	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
k59_1549227_1	159087.Daro_2874	1.45e-99	300.0	COG3213@1|root,COG3213@2|Bacteria,1MUJK@1224|Proteobacteria,2VJ75@28216|Betaproteobacteria,2KV9W@206389|Rhodocyclales	206389|Rhodocyclales	P	NnrS protein	-	-	-	ko:K07234	-	-	-	-	ko00000	-	-	-	NnrS
k59_1663550_2	640081.Dsui_0506	9.47e-10	59.7	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,EAL,GAF_2,GGDEF,PAS_3,PAS_4
k59_1603936_1	1537917.JU82_06250	1.63e-120	358.0	COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,42N0P@68525|delta/epsilon subdivisions,2YN14@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	UPF0313 protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,Radical_SAM_N
k59_1842902_1	709032.Sulku_0568	5.82e-47	163.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,42M1K@68525|delta/epsilon subdivisions,2YMKR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the peptidase M24B family	pepQ	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
k59_1842902_2	1537917.JU82_03220	3.4e-24	94.7	COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,42S69@68525|delta/epsilon subdivisions,2YP0K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	cheW	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
k59_1077085_1	259536.Psyc_0479	1.29e-12	72.4	COG0582@1|root,COG0582@2|Bacteria,1MVZB@1224|Proteobacteria,1RP4Y@1236|Gammaproteobacteria,3NK6F@468|Moraxellaceae	1236|Gammaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K14059	-	-	-	-	ko00000	-	-	-	Arm-DNA-bind_2,Phage_integrase
k59_1549271_1	159087.Daro_3979	7.85e-56	175.0	COG0375@1|root,COG0375@2|Bacteria,1MZJH@1224|Proteobacteria,2VUFZ@28216|Betaproteobacteria,2KX2G@206389|Rhodocyclales	206389|Rhodocyclales	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
k59_1549271_2	159087.Daro_3980	4.3e-40	141.0	COG0374@1|root,COG0374@2|Bacteria,1R6ND@1224|Proteobacteria,2VQXM@28216|Betaproteobacteria,2KXDB@206389|Rhodocyclales	206389|Rhodocyclales	C	Ni,Fe-hydrogenase I large subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_74945_1	159087.Daro_3558	1e-104	320.0	COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,2VH62@28216|Betaproteobacteria,2KV3X@206389|Rhodocyclales	206389|Rhodocyclales	T	Domain of unknown function (DUF4118)	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,GAF_3,HATPase_c,HisKA
k59_194074_1	1537917.JU82_00675	1.75e-102	303.0	COG1120@1|root,COG1120@2|Bacteria,1PFA0@1224|Proteobacteria,42UVB@68525|delta/epsilon subdivisions,2YPUB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	HP	COGs COG1120 ABC-type cobalamin Fe3 -siderophores transport systems ATPase components	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
k59_194074_2	1537917.JU82_00670	1.59e-15	74.3	COG0614@1|root,COG0614@2|Bacteria,1MWVF@1224|Proteobacteria,42SMM@68525|delta/epsilon subdivisions,2YPJY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
k59_18981_1	1249480.B649_08750	8.35e-88	261.0	COG1619@1|root,COG1619@2|Bacteria,1Q23R@1224|Proteobacteria,42UXX@68525|delta/epsilon subdivisions,2YPD5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	proteins homologs of microcin C7 resistance protein MccF	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1431537_1	1165841.SULAR_08322	4.98e-55	176.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,42QSI@68525|delta/epsilon subdivisions,2YNXJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	protein-L-isoaspartate O-methyltransferase	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
k59_1431537_2	1165841.SULAR_08282	3.79e-55	181.0	2AHSQ@1|root,31858@2|Bacteria,1PZUK@1224|Proteobacteria,42XTR@68525|delta/epsilon subdivisions,2YQVH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3972
k59_1487672_1	1249480.B649_01200	6.19e-130	385.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2YN0B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
k59_900125_1	1304883.KI912532_gene2092	2.86e-46	153.0	COG0526@1|root,COG0526@2|Bacteria,1MZ5J@1224|Proteobacteria,2VU93@28216|Betaproteobacteria,2KWJG@206389|Rhodocyclales	206389|Rhodocyclales	O	COG0526 Thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
k59_900125_2	159087.Daro_1562	9.76e-63	199.0	COG1668@1|root,COG1668@2|Bacteria,1QWGC@1224|Proteobacteria,2WGYV@28216|Betaproteobacteria,2KZQ1@206389|Rhodocyclales	206389|Rhodocyclales	CP	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
k59_74967_1	1537917.JU82_05970	1.02e-46	154.0	2AJ46@1|root,319NN@2|Bacteria,1Q3CI@1224|Proteobacteria,42X3N@68525|delta/epsilon subdivisions,2YQT6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	LTXXQ,Metal_resist
k59_74967_2	709032.Sulku_1468	5.7e-78	236.0	COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,42QPB@68525|delta/epsilon subdivisions,2YNVC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Chemotaxis protein CheY	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_1487687_1	749222.Nitsa_0408	1.54e-19	92.4	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42NFR@68525|delta/epsilon subdivisions,2YMNU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS,PAS_3,PAS_9
k59_1192906_1	1158182.KB905022_gene1133	1.39e-06	51.2	COG2199@1|root,COG3706@2|Bacteria,1R895@1224|Proteobacteria,1RSDW@1236|Gammaproteobacteria,1X0Q1@135613|Chromatiales	135613|Chromatiales	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GGDEF,PAS,PAS_4
k59_1192906_2	159087.Daro_1596	4.4e-60	187.0	COG2197@1|root,COG2197@2|Bacteria,1MZVM@1224|Proteobacteria,2VUT0@28216|Betaproteobacteria,2KX16@206389|Rhodocyclales	206389|Rhodocyclales	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
k59_194117_1	1123326.JFBL01000001_gene1377	2.78e-43	160.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42TH4@68525|delta/epsilon subdivisions,2YRFX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_3
k59_1307848_1	1304883.KI912532_gene2460	1.66e-251	712.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,2VIE5@28216|Betaproteobacteria,2KV38@206389|Rhodocyclales	206389|Rhodocyclales	J	Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs	rne	-	3.1.26.12	ko:K08300	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
k59_1309611_3	1537917.JU82_09210	3.23e-33	127.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,42NGS@68525|delta/epsilon subdivisions,2YMZZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Ribonuclease	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB
k59_431600_1	1229205.BUPH_04703	2.62e-12	67.8	COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,2VHS4@28216|Betaproteobacteria,1K2HP@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide	hypF2	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
k59_431600_2	1537917.JU82_09400	4.43e-59	199.0	COG0068@1|root,COG0068@2|Bacteria,1Q0S6@1224|Proteobacteria,42SF1@68525|delta/epsilon subdivisions,2YPJ0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	HypF finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HYPF
k59_1259003_2	1537917.JU82_05940	5.74e-67	207.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,42RN6@68525|delta/epsilon subdivisions,2YP9W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
k59_554902_1	857087.Metme_1197	5.86e-44	158.0	COG0472@1|root,COG0472@2|Bacteria,1MWYW@1224|Proteobacteria,1RNAP@1236|Gammaproteobacteria,1XF34@135618|Methylococcales	135618|Methylococcales	M	PFAM Glycosyl transferase family 4	-	-	-	ko:K13007	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
k59_493748_1	205914.HS_0456	2.68e-33	130.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,1RN3R@1236|Gammaproteobacteria,1Y71A@135625|Pasteurellales	135625|Pasteurellales	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
k59_1259009_1	717772.THIAE_03760	4.45e-22	89.7	COG0720@1|root,COG0720@2|Bacteria,1RI4P@1224|Proteobacteria,1S3T6@1236|Gammaproteobacteria,46112@72273|Thiotrichales	72273|Thiotrichales	H	queuosine biosynthesis protein QueD	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
k59_1259009_2	317025.Tcr_1391	8.28e-14	72.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,1RN90@1236|Gammaproteobacteria,460AW@72273|Thiotrichales	72273|Thiotrichales	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
k59_1845695_1	1123517.JOMR01000001_gene670	1.17e-17	81.6	2E62S@1|root,330RV@2|Bacteria,1N7P9@1224|Proteobacteria,1SHBI@1236|Gammaproteobacteria,461I4@72273|Thiotrichales	72273|Thiotrichales	S	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
k59_1434418_1	509191.AEDB02000067_gene921	3.26e-77	259.0	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,2490U@186801|Clostridia,3WGCA@541000|Ruminococcaceae	186801|Clostridia	Q	TIGRFAM amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,ketoacyl-synt
k59_196532_1	1249480.B649_10310	9.62e-91	277.0	COG0658@1|root,COG0658@2|Bacteria,1PY6P@1224|Proteobacteria,42NU2@68525|delta/epsilon subdivisions,2YME0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Competence protein	comE	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence
k59_610080_1	1537917.JU82_06810	1.7e-75	248.0	COG0835@1|root,COG0835@2|Bacteria,1QVCF@1224|Proteobacteria,42M0F@68525|delta/epsilon subdivisions,2YNAP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	PFAM CheW domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CheW,dCache_1
k59_671933_1	1537917.JU82_08620	1.42e-99	311.0	COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,42M8J@68525|delta/epsilon subdivisions,2YNGB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member	recD	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2,Viral_helicase1
k59_671937_1	93220.LV28_04715	7.83e-75	242.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,2VH45@28216|Betaproteobacteria,1K2AT@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Sulfate permease family	sulP	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k59_196561_1	929558.SMGD1_0313	2.8e-11	62.0	2A51M@1|root,30TPZ@2|Bacteria,1Q07Y@1224|Proteobacteria,42RR3@68525|delta/epsilon subdivisions,2YP94@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1552140_1	1537917.JU82_04015	1.02e-10	61.6	COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,42MQQ@68525|delta/epsilon subdivisions,2YNAG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	dna polymerase iii	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_1552140_2	709032.Sulku_0368	8.63e-112	324.0	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,42QQ3@68525|delta/epsilon subdivisions,2YNYX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
k59_493803_1	1005999.GLGR_3548	3.23e-116	347.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,1S087@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
k59_901993_1	913865.DOT_4269	1.98e-81	250.0	COG5464@1|root,COG5464@2|Bacteria	2|Bacteria	S	double-stranded DNA endodeoxyribonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
k59_610134_1	653733.Selin_0203	3.69e-66	224.0	COG0058@1|root,COG0058@2|Bacteria	2|Bacteria	G	glycogen phosphorylase activity	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
k59_1079342_1	159087.Daro_0209	7.52e-99	309.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,2VHXF@28216|Betaproteobacteria,2KU7U@206389|Rhodocyclales	206389|Rhodocyclales	M	penicillin-binding protein 1A	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
k59_784144_1	1565314.OA34_08215	7.24e-90	278.0	COG0662@1|root,COG0836@1|root,COG0662@2|Bacteria,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,42MDP@68525|delta/epsilon subdivisions,2YMW3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	GM	Belongs to the mannose-6-phosphate isomerase type 2 family	manC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
k59_1723749_1	159087.Daro_0919	4.46e-75	239.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,2VHN4@28216|Betaproteobacteria,2KUCB@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
k59_1140174_1	1321782.HMPREF1986_02694	2.36e-05	46.6	COG3326@1|root,COG3326@2|Bacteria,1VEJY@1239|Firmicutes,24QJW@186801|Clostridia,2PSN8@265975|Oribacterium	186801|Clostridia	S	Protein of unknown function (DUF1294)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1294
k59_1140174_2	1537917.JU82_03965	2.52e-73	222.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2YPJX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
k59_671998_1	709032.Sulku_2182	4.84e-91	277.0	COG0658@1|root,COG0658@2|Bacteria,1PY6P@1224|Proteobacteria,42NU2@68525|delta/epsilon subdivisions,2YME0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Competence protein	comE	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence
k59_142044_1	1382356.JQMP01000003_gene1423	3.52e-27	114.0	COG1316@1|root,COG1316@2|Bacteria,2G6PZ@200795|Chloroflexi,27XRZ@189775|Thermomicrobia	189775|Thermomicrobia	K	cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
k59_1309705_1	642492.Clole_1077	2.25e-19	86.3	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia	186801|Clostridia	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
k59_555019_1	1121035.AUCH01000007_gene579	6.2e-23	97.4	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,2VH1K@28216|Betaproteobacteria,2KUE7@206389|Rhodocyclales	206389|Rhodocyclales	O	Belongs to the ClpA ClpB family	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_555019_2	159087.Daro_3096	6.03e-107	309.0	COG0684@1|root,COG0684@2|Bacteria,1RH18@1224|Proteobacteria,2VR2C@28216|Betaproteobacteria,2KW8N@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions	-	-	-	ko:K02553	-	-	-	-	ko00000,ko03019	-	-	-	RraA-like
k59_1371722_1	159087.Daro_1631	7.12e-97	307.0	COG0591@1|root,COG0642@1|root,COG0591@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,2VKRS@28216|Betaproteobacteria,2KUB6@206389|Rhodocyclales	206389|Rhodocyclales	ET	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_1434542_2	1322246.BN4_11317	9.15e-07	52.8	COG2703@1|root,COG2703@2|Bacteria,1N8CP@1224|Proteobacteria,42NR3@68525|delta/epsilon subdivisions,2X0UH@28221|Deltaproteobacteria,2MDFR@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM Hemerythrin HHE cation binding domain protein	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
k59_1371738_1	1288494.EBAPG3_25000	3.4e-60	209.0	COG0642@1|root,COG0784@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria,374RC@32003|Nitrosomonadales	28216|Betaproteobacteria	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HAMP,HATPase_c,HisKA,Hpt,MHYT,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
k59_610191_1	1537917.JU82_03795	2.92e-89	292.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2YMJS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,NIT,Response_reg
k59_1489649_1	709032.Sulku_1000	9.72e-114	328.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,42M8E@68525|delta/epsilon subdivisions,2YPCE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
k59_431716_2	1537917.JU82_06370	9.92e-17	78.6	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,42M94@68525|delta/epsilon subdivisions,2YMQM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
k59_1259158_1	425400.LS65_00685	8.12e-09	57.8	COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,42MPN@68525|delta/epsilon subdivisions,2YMHV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Flagellar basal body protein	flgE	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bb_rod,Flg_bbr_C
k59_1259158_2	1537917.JU82_03140	1.9e-54	176.0	COG1843@1|root,COG1843@2|Bacteria,1PQS2@1224|Proteobacteria,42TAQ@68525|delta/epsilon subdivisions,2YPFZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Required for flagellar hook formation. May act as a scaffolding protein	flgD	-	-	ko:K02389	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgD,FlgD_ig
k59_555064_1	273121.WS1445	6.09e-54	191.0	COG3513@1|root,COG3513@2|Bacteria,1MVT9@1224|Proteobacteria,42NWE@68525|delta/epsilon subdivisions,2YMX9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer	cas9	-	-	ko:K09952	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH_4
k59_1259168_2	1249480.B649_07150	9.9e-41	141.0	COG1076@1|root,COG1076@2|Bacteria,1N270@1224|Proteobacteria,42STV@68525|delta/epsilon subdivisions,2YPJ5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	DnaJ domain protein	-	-	-	ko:K05801	-	-	-	-	ko00000,ko03110	-	-	-	DnaJ,TerB
k59_610216_1	1304883.KI912532_gene1867	4.71e-27	99.8	COG2608@1|root,COG2608@2|Bacteria,1NGBD@1224|Proteobacteria,2VXV9@28216|Betaproteobacteria,2KXPB@206389|Rhodocyclales	206389|Rhodocyclales	P	Heavy-metal-associated domain	-	-	-	ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
k59_610216_2	159087.Daro_1052	2.41e-49	172.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KYB0@206389|Rhodocyclales	206389|Rhodocyclales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_1723808_1	204536.SULAZ_0730	2.64e-29	117.0	COG3696@1|root,COG3696@2|Bacteria	2|Bacteria	P	silver ion transport	czcA	-	-	ko:K07787,ko:K15726	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.2,2.A.6.1.4	-	-	ACR_tran
k59_1723808_2	470.IX87_20165	1.42e-13	70.9	COG0745@1|root,COG0745@2|Bacteria,1MVQT@1224|Proteobacteria,1RNSY@1236|Gammaproteobacteria,3NKVZ@468|Moraxellaceae	1236|Gammaproteobacteria	KT	Transcriptional regulatory protein, C terminal	-	-	-	ko:K18144	ko01501,map01501	M00649,M00655	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_1845863_1	1177179.A11A3_13685	5.46e-49	163.0	COG0431@1|root,COG0431@2|Bacteria,1RAFI@1224|Proteobacteria,1RYNR@1236|Gammaproteobacteria,1XMHW@135619|Oceanospirillales	135619|Oceanospirillales	S	Chromate reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
k59_142134_1	1150469.RSPPHO_01651	6.88e-62	215.0	COG0642@1|root,COG3829@1|root,COG5002@1|root,COG0642@2|Bacteria,COG3829@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2TZDS@28211|Alphaproteobacteria,2JZ03@204441|Rhodospirillales	204441|Rhodospirillales	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,Response_reg
k59_1259203_1	709032.Sulku_0082	1.11e-88	265.0	COG2836@1|root,COG2836@2|Bacteria,1RIGJ@1224|Proteobacteria,42Q44@68525|delta/epsilon subdivisions,2YNTJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
k59_311996_1	887062.HGR_11650	8.59e-103	312.0	COG1492@1|root,COG1492@2|Bacteria,1MUFY@1224|Proteobacteria,2VII5@28216|Betaproteobacteria,4AC9X@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,CbiA,GATase_3
k59_1665806_1	522306.CAP2UW1_0825	1.01e-126	371.0	COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,2VJF4@28216|Betaproteobacteria	28216|Betaproteobacteria	H	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site	cbbM	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
k59_610269_1	1255043.TVNIR_2980	1.51e-61	201.0	COG3329@1|root,COG3329@2|Bacteria,1N85P@1224|Proteobacteria,1RRX7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	permease	-	-	-	ko:K07086	-	-	-	-	ko00000	-	-	-	Sbt_1
k59_1782406_2	709032.Sulku_0046	7.65e-63	203.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,42MS9@68525|delta/epsilon subdivisions,2YMBY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
k59_1195186_2	1249480.B649_08130	2.06e-37	140.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42UBD@68525|delta/epsilon subdivisions,2YRGP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	7TM diverse intracellular signalling	-	-	-	ko:K20971	ko02025,map02025	-	-	-	ko00000,ko00001,ko01001,ko02022	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c
k59_1606293_1	159087.Daro_1735	3.13e-12	65.1	COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,2VH00@28216|Betaproteobacteria,2KUS0@206389|Rhodocyclales	206389|Rhodocyclales	M	UTP-glucose-1-phosphate uridylyltransferase	epsT	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
k59_1606293_2	159087.Daro_1736	1.32e-117	337.0	COG0634@1|root,COG0634@2|Bacteria,1NRT8@1224|Proteobacteria,2VRM9@28216|Betaproteobacteria,2KVMU@206389|Rhodocyclales	206389|Rhodocyclales	F	phosphoribosyltransferase	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
k59_555161_1	1537917.JU82_05100	2.13e-130	376.0	COG0208@1|root,COG0208@2|Bacteria,1MWUS@1224|Proteobacteria,42ME8@68525|delta/epsilon subdivisions,2YN4W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdB	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
k59_555161_2	709032.Sulku_2534	5.84e-49	175.0	COG3164@1|root,COG3164@2|Bacteria,1QUYX@1224|Proteobacteria,43CES@68525|delta/epsilon subdivisions,2YTC9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
k59_1309805_1	1249480.B649_04160	1.43e-220	615.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,42MG8@68525|delta/epsilon subdivisions,2YMAP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
k59_1665840_1	159087.Daro_1044	4.61e-89	284.0	COG4772@1|root,COG4772@2|Bacteria,1MUIH@1224|Proteobacteria,2VKC9@28216|Betaproteobacteria,2KVU2@206389|Rhodocyclales	206389|Rhodocyclales	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_1845955_1	1304883.KI912532_gene2931	3.27e-36	129.0	COG0265@1|root,COG0265@2|Bacteria,1R9ZV@1224|Proteobacteria,2VQ55@28216|Betaproteobacteria,2KW3P@206389|Rhodocyclales	206389|Rhodocyclales	O	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
k59_1782448_1	1123517.JOMR01000001_gene1888	2.25e-61	212.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,1RMK0@1236|Gammaproteobacteria,46008@72273|Thiotrichales	72273|Thiotrichales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_20718_1	1249480.B649_10450	6.78e-41	136.0	COG2863@1|root,COG2863@2|Bacteria,1PG8Y@1224|Proteobacteria,42VJJ@68525|delta/epsilon subdivisions,2YQGV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
k59_20718_2	1537917.JU82_08590	2.75e-52	176.0	COG5002@1|root,COG5002@2|Bacteria,1QZ29@1224|Proteobacteria,43CEG@68525|delta/epsilon subdivisions,2YTC2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_672205_1	1492737.FEM08_17280	3.57e-72	238.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,1HZAM@117743|Flavobacteriia,2NYPF@237|Flavobacterium	976|Bacteroidetes	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
k59_1845975_1	156889.Mmc1_3492	5.12e-19	84.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,2TRWR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
k59_1845975_2	203122.Sde_2698	1.72e-97	298.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,1RMYV@1236|Gammaproteobacteria,464C4@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
k59_1723901_1	1502770.JQMG01000001_gene604	5.59e-22	89.7	COG3168@1|root,COG3168@2|Bacteria,1RI6V@1224|Proteobacteria,2VSVR@28216|Betaproteobacteria,2KMV4@206350|Nitrosomonadales	206350|Nitrosomonadales	NU	PFAM Pilus assembly protein PilP	-	-	-	ko:K02665	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilP
k59_1723901_2	666681.M301_2564	4.53e-44	159.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,2VHY4@28216|Betaproteobacteria,2KKNT@206350|Nitrosomonadales	206350|Nitrosomonadales	U	type II and III secretion system protein	-	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
k59_1875141_1	296591.Bpro_2750	4.97e-76	234.0	COG1024@1|root,COG1024@2|Bacteria,1MXBB@1224|Proteobacteria,2VNFE@28216|Betaproteobacteria,4ABZE@80864|Comamonadaceae	28216|Betaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
k59_868431_1	709032.Sulku_0307	9.68e-117	345.0	COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,42MRJ@68525|delta/epsilon subdivisions,2YMF2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,UPF0004
k59_744158_1	1304883.KI912532_gene752	4.8e-26	97.1	COG2960@1|root,COG2960@2|Bacteria,1N7AH@1224|Proteobacteria,2VVR4@28216|Betaproteobacteria,2KX84@206389|Rhodocyclales	206389|Rhodocyclales	S	Membrane fusogenic activity	-	-	-	ko:K09806	-	-	-	-	ko00000	-	-	-	BMFP
k59_744158_2	159087.Daro_0052	1.33e-22	93.6	2DQY9@1|root,339CR@2|Bacteria,1NR8Y@1224|Proteobacteria,2VNF6@28216|Betaproteobacteria,2KWEJ@206389|Rhodocyclales	206389|Rhodocyclales	S	Bacterial protein of unknown function (Gcw_chp)	-	-	-	-	-	-	-	-	-	-	-	-	Gcw_chp
k59_336381_1	626887.J057_21605	3.52e-64	214.0	COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,1RNCS@1236|Gammaproteobacteria,4650M@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Uncharacterized ACR, YdiU/UPF0061 family	-	-	-	-	-	-	-	-	-	-	-	-	UPF0061
k59_45175_1	358220.C380_02335	8.49e-128	374.0	COG2223@1|root,COG2223@2|Bacteria,1MU27@1224|Proteobacteria,2VI5E@28216|Betaproteobacteria,4ABQV@80864|Comamonadaceae	28216|Betaproteobacteria	P	nitrite transporter	narK	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1
k59_283445_1	709032.Sulku_2147	8.54e-115	353.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2YMI5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	cation transport ATPase	ccoI	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
k59_1288831_1	326298.Suden_1687	1.1e-145	416.0	COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,42NIA@68525|delta/epsilon subdivisions,2YR33@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	HJ	Belongs to the RimK family	rimK	-	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK
k59_1288831_2	929558.SMGD1_1458	1.41e-71	218.0	COG4067@1|root,COG4067@2|Bacteria,1RGX8@1224|Proteobacteria,42U6Y@68525|delta/epsilon subdivisions,2YRSZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Putative ATP-dependant zinc protease	-	-	-	-	-	-	-	-	-	-	-	-	Zn_protease
k59_1288831_3	929558.SMGD1_1847	8.42e-105	313.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria	1224|Proteobacteria	H	polyphosphate kinase	-	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
k59_1691934_2	296591.Bpro_3939	2.79e-41	141.0	COG1077@1|root,COG1077@2|Bacteria,1RK8H@1224|Proteobacteria,2VT45@28216|Betaproteobacteria,4AESU@80864|Comamonadaceae	28216|Betaproteobacteria	D	MreB/Mbl protein	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
k59_1288836_1	1249480.B649_02780	1.94e-62	204.0	COG0642@1|root,COG0642@2|Bacteria,1N5IQ@1224|Proteobacteria,42M9P@68525|delta/epsilon subdivisions,2YN0U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	cprS	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
k59_45195_1	709032.Sulku_0636	5.77e-42	140.0	COG0662@1|root,COG0662@2|Bacteria,1QUHG@1224|Proteobacteria,43BPC@68525|delta/epsilon subdivisions,2YQZE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	PFAM Cupin 2 conserved barrel domain protein	-	-	-	ko:K11312	-	-	-	-	ko00000	-	-	-	Cupin_2
k59_402055_2	159087.Daro_3000	2.86e-57	192.0	COG1807@1|root,COG1807@2|Bacteria,1PUE3@1224|Proteobacteria,2VHPU@28216|Betaproteobacteria,2KUEG@206389|Rhodocyclales	206389|Rhodocyclales	M	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
k59_1811657_2	709032.Sulku_2151	3.07e-68	214.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,42MCV@68525|delta/epsilon subdivisions,2YMK7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
k59_462650_1	1121035.AUCH01000002_gene1672	1.08e-74	235.0	COG0683@1|root,COG0683@2|Bacteria,1MWR8@1224|Proteobacteria,2VHH6@28216|Betaproteobacteria,2KVK6@206389|Rhodocyclales	206389|Rhodocyclales	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
k59_174601_1	1137268.AZXF01000013_gene1524	0.000111	45.8	COG0303@1|root,COG0303@2|Bacteria,2GJC3@201174|Actinobacteria,4EHQA@85012|Streptosporangiales	201174|Actinobacteria	H	MoeA C-terminal region (domain IV)	moeA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0071944,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657	2.10.1.1,2.7.7.9	ko:K00963,ko:K03750	ko00040,ko00052,ko00500,ko00520,ko00790,ko01100,ko01130,map00040,map00052,map00500,map00520,map00790,map01100,map01130	M00129,M00361,M00362,M00549	R00289,R09735	RC00002,RC03462	ko00000,ko00001,ko00002,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
k59_174607_1	1249480.B649_04315	1.99e-123	375.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,42MW3@68525|delta/epsilon subdivisions,2YMT6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
k59_747728_2	563040.Saut_1799	2.06e-15	78.6	COG2165@1|root,COG2165@2|Bacteria,1QUIZ@1224|Proteobacteria,43BJB@68525|delta/epsilon subdivisions,2YTBR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_936829_1	556267.HWAG_00306	8.68e-35	129.0	28HSZ@1|root,2Z7ZZ@2|Bacteria,1PKZD@1224|Proteobacteria,42ZWZ@68525|delta/epsilon subdivisions,2YRUX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_525107_1	159087.Daro_0618	1.06e-51	172.0	COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,2VHZZ@28216|Betaproteobacteria,2KUW8@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
k59_1403046_1	269799.Gmet_2163	1.1e-52	189.0	COG2132@1|root,COG5263@1|root,COG2132@2|Bacteria,COG5263@2|Bacteria,1R9AF@1224|Proteobacteria,42YQG@68525|delta/epsilon subdivisions,2WTP2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Multicopper oxidase	ompB	-	-	-	-	-	-	-	-	-	-	-	ASH,Cu-oxidase_2
k59_525114_1	709032.Sulku_1439	8.85e-48	163.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,42MKY@68525|delta/epsilon subdivisions,2YMUR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
k59_525114_2	1249480.B649_05980	1.02e-58	200.0	COG2319@1|root,COG2319@2|Bacteria,1Q4XR@1224|Proteobacteria,42PRP@68525|delta/epsilon subdivisions,2YMZB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	WD40
k59_936838_1	1122599.AUGR01000001_gene403	5.46e-58	186.0	COG4567@1|root,COG4567@2|Bacteria,1RD7J@1224|Proteobacteria,1S3PE@1236|Gammaproteobacteria,1XJHE@135619|Oceanospirillales	135619|Oceanospirillales	T	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain	-	-	-	ko:K15012	ko02020,map02020	M00523	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg
k59_936838_2	1122212.AULO01000007_gene2467	8.15e-14	74.3	COG4191@1|root,COG4191@2|Bacteria,1MWR3@1224|Proteobacteria,1RMH4@1236|Gammaproteobacteria,1XH8P@135619|Oceanospirillales	135619|Oceanospirillales	T	Histidine kinase	-	-	2.7.13.3	ko:K15011	ko02020,map02020	M00523	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c
k59_1226282_1	709032.Sulku_1021	1.9e-118	356.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,42MP3@68525|delta/epsilon subdivisions,2YMP3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
k59_174687_1	742727.HMPREF9447_03931	1.13e-36	137.0	COG1143@1|root,COG1143@2|Bacteria,4NUKI@976|Bacteroidetes,2FNG5@200643|Bacteroidia,4AQ0K@815|Bacteroidaceae	976|Bacteroidetes	C	4Fe-4S dicluster domain	asrA	-	-	-	-	-	-	-	-	-	-	-	Fer4_22
k59_644577_1	387093.SUN_0320	5.97e-148	427.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,42MG2@68525|delta/epsilon subdivisions,2YMJH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
k59_288089_2	1539298.JO41_10290	3.65e-07	55.1	COG0566@1|root,COG0566@2|Bacteria,2J5HI@203691|Spirochaetes	203691|Spirochaetes	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	-	ko:K03214	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
k59_819665_1	90813.JQMT01000001_gene1919	5.55e-29	111.0	COG5456@1|root,COG5456@2|Bacteria,1RFTY@1224|Proteobacteria,1S4W0@1236|Gammaproteobacteria,461B6@72273|Thiotrichales	72273|Thiotrichales	P	FixH	-	-	-	-	-	-	-	-	-	-	-	-	FixH
k59_1696005_1	1249480.B649_10600	3.49e-56	189.0	COG1450@1|root,COG1450@2|Bacteria,1QXWT@1224|Proteobacteria,43CKP@68525|delta/epsilon subdivisions,2YN73@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	COG1450 Type II secretory pathway component PulD	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N_2
k59_1343190_1	509191.AEDB02000021_gene3098	2.2e-09	60.5	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,3WHUP@541000|Ruminococcaceae	186801|Clostridia	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Thioredoxin
k59_1110972_1	1304883.KI912532_gene2353	7.53e-103	309.0	COG2718@1|root,COG2718@2|Bacteria,1MWQM@1224|Proteobacteria,2VJE2@28216|Betaproteobacteria,2KV9U@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the UPF0229 family	-	-	-	ko:K09786	-	-	-	-	ko00000	-	-	-	DUF444
k59_174713_1	1249480.B649_01315	4.95e-09	55.5	COG3166@1|root,COG3166@2|Bacteria,1Q1VC@1224|Proteobacteria,42UGS@68525|delta/epsilon subdivisions,2YPY1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	PFAM Fimbrial assembly family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_174713_2	1537917.JU82_09955	2.55e-68	220.0	2BQX9@1|root,32JUG@2|Bacteria,1Q2H0@1224|Proteobacteria,42VPF@68525|delta/epsilon subdivisions,2YQMK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_819683_1	658612.MD26_03980	2.74e-39	150.0	COG0243@1|root,COG0369@1|root,COG0243@2|Bacteria,COG0369@2|Bacteria,1NS3T@1224|Proteobacteria,1RMWN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Catalytic subunit of the nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC. Essential function for nitrate assimilation and may have a role in anaerobic metabolism	narB	-	1.8.1.2	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_1,Flavodoxin_1,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NAD_binding_1
k59_1110981_1	1537917.JU82_03250	1.21e-190	545.0	COG2199@1|root,COG2200@1|root,COG3620@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,COG3620@2|Bacteria,1MVJY@1224|Proteobacteria,42N7E@68525|delta/epsilon subdivisions,2YNE7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PFAM EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF
k59_174725_1	1249480.B649_10375	2.97e-38	135.0	2C2VD@1|root,338G0@2|Bacteria,1P3HX@1224|Proteobacteria,42NM6@68525|delta/epsilon subdivisions,2YM9Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_174725_2	1249480.B649_10370	7.81e-106	310.0	COG1387@1|root,COG1387@2|Bacteria,1RCEG@1224|Proteobacteria,42MIM@68525|delta/epsilon subdivisions,2YMFF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	histidinol phosphate phosphatase	hisJ	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP,PHP_C
k59_340845_2	709032.Sulku_1962	3.47e-148	433.0	COG2199@1|root,COG2202@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42M3W@68525|delta/epsilon subdivisions,2YMI6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	SMART GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GGDEF,PAS_3,PAS_9
k59_340845_3	709032.Sulku_1962	1.42e-80	254.0	COG2199@1|root,COG2202@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42M3W@68525|delta/epsilon subdivisions,2YMI6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	SMART GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GGDEF,PAS_3,PAS_9
k59_105183_1	1249480.B649_02835	2.24e-56	187.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,42M1K@68525|delta/epsilon subdivisions,2YMKR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the peptidase M24B family	pepQ	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
k59_1639928_1	709032.Sulku_1223	2.84e-24	100.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,42M9I@68525|delta/epsilon subdivisions,2YNRH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	general secretion pathway protein D	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
k59_1639928_2	709032.Sulku_1223	7.03e-70	226.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,42M9I@68525|delta/epsilon subdivisions,2YNRH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	general secretion pathway protein D	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
k59_819710_1	395494.Galf_1193	2.15e-81	249.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,2VHYP@28216|Betaproteobacteria,44VDI@713636|Nitrosomonadales	28216|Betaproteobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
k59_644641_2	1249480.B649_10370	9.27e-09	55.1	COG1387@1|root,COG1387@2|Bacteria,1RCEG@1224|Proteobacteria,42MIM@68525|delta/epsilon subdivisions,2YMFF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	histidinol phosphate phosphatase	hisJ	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP,PHP_C
k59_1403154_1	272134.KB731325_gene532	1.87e-56	193.0	COG4584@1|root,COG4584@2|Bacteria,1G3MH@1117|Cyanobacteria,1HEGV@1150|Oscillatoriales	1117|Cyanobacteria	L	PFAM Integrase, catalytic core	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_174768_1	709032.Sulku_0806	2.33e-153	440.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2YMTZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iIT341.HP0623	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_174779_1	1537917.JU82_08040	6.52e-91	288.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2YMW4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_819749_1	1279019.ARQK01000047_gene1036	9.36e-45	162.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,1WWE0@135613|Chromatiales	135613|Chromatiales	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
k59_1226396_1	205918.Psyr_3088	2.45e-57	192.0	COG0438@1|root,COG0438@2|Bacteria,1NJ19@1224|Proteobacteria,1RQ2I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Gkycosyl transferase family 4 group	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_3,Glycos_transf_1
k59_288203_1	709032.Sulku_0613	1.9e-39	146.0	2AJ4C@1|root,319NV@2|Bacteria,1Q3D8@1224|Proteobacteria,431S6@68525|delta/epsilon subdivisions,2YS5U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_174833_2	580332.Slit_0335	2.51e-21	87.4	arCOG05276@1|root,3195F@2|Bacteria,1RHZA@1224|Proteobacteria,2VSYY@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_174833_3	1249480.B649_04515	2.08e-79	236.0	COG2768@1|root,COG2768@2|Bacteria,1R1K0@1224|Proteobacteria,43DAC@68525|delta/epsilon subdivisions,2YTHE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_7,Fer4_9
k59_402336_2	1219031.BBJR01000038_gene3046	1.4e-30	117.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,2VH7U@28216|Betaproteobacteria,4A9S3@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
k59_462954_1	709032.Sulku_1915	1.03e-64	213.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,42M35@68525|delta/epsilon subdivisions,2YM7I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0354	DXP_synthase_N,Transket_pyr,Transketolase_C
k59_402340_1	1123255.JHYS01000007_gene1664	5.06e-72	224.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2VM4B@28216|Betaproteobacteria,4AIYR@80864|Comamonadaceae	28216|Betaproteobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_402340_2	1123255.JHYS01000007_gene1665	5.35e-30	114.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,2VIDW@28216|Betaproteobacteria,4ABK5@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_1403245_1	1249480.B649_05605	7.79e-119	342.0	COG2932@1|root,COG2932@2|Bacteria,1RIP6@1224|Proteobacteria,42RJG@68525|delta/epsilon subdivisions,2YP8P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	phage repressor	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24,Phage_CI_repr
k59_288248_2	1298593.TOL_0020	3.02e-10	60.1	COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,1RMYI@1236|Gammaproteobacteria,1XHG1@135619|Oceanospirillales	135619|Oceanospirillales	J	glycyl-tRNA synthetase alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
k59_1696155_1	1249480.B649_08720	1.11e-117	350.0	COG4972@1|root,COG4972@2|Bacteria,1QA6M@1224|Proteobacteria,42NDB@68525|delta/epsilon subdivisions,2YMP2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Pilus assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_747952_1	932213.SPM24T3_00890	1.57e-71	238.0	COG1262@1|root,COG2227@1|root,COG1262@2|Bacteria,COG2227@2|Bacteria,1MUNC@1224|Proteobacteria,1RQI4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	methyltransferase	sumf2	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase,Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25,Methyltransf_31
k59_288252_1	1249480.B649_03325	1.1e-34	129.0	COG1807@1|root,COG1807@2|Bacteria,1Q901@1224|Proteobacteria,42MGX@68525|delta/epsilon subdivisions,2YNER@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
k59_288252_3	1249480.B649_03315	2.48e-87	265.0	COG1060@1|root,COG1060@2|Bacteria,1QN23@1224|Proteobacteria,42M6Z@68525|delta/epsilon subdivisions,2YMA7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate	mqnE	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
k59_228739_1	1537917.JU82_00460	1.33e-126	367.0	COG0739@1|root,COG0739@2|Bacteria,1MY2X@1224|Proteobacteria,42U06@68525|delta/epsilon subdivisions,2YP2U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_228739_2	709032.Sulku_0118	3.96e-22	91.3	COG3248@1|root,COG3248@2|Bacteria,1RC26@1224|Proteobacteria,42V71@68525|delta/epsilon subdivisions,2YRU5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Nucleoside-specific channel-forming protein, Tsx	-	-	-	-	-	-	-	-	-	-	-	-	Channel_Tsx
k59_1226492_1	1249480.B649_00870	2.15e-16	80.5	COG0790@1|root,COG0790@2|Bacteria	2|Bacteria	S	beta-lactamase activity	exoR	-	-	ko:K07126,ko:K19292	-	-	-	-	ko00000	-	-	-	Sel1
k59_105341_1	1537917.JU82_07640	6.61e-189	533.0	COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,42M78@68525|delta/epsilon subdivisions,2YMR1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
k59_1811911_1	709032.Sulku_2308	2.43e-129	368.0	COG0720@1|root,COG0720@2|Bacteria,1R62M@1224|Proteobacteria,42R4Z@68525|delta/epsilon subdivisions,2YNZW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	synthase	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
k59_402410_1	580332.Slit_2223	5.79e-76	246.0	COG1305@1|root,COG1305@2|Bacteria,1MWCE@1224|Proteobacteria,2VHZP@28216|Betaproteobacteria,44WEH@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Domain of unknown function (DUF3488)	-	-	2.3.2.13	ko:K22452	-	-	-	-	ko00000,ko01000	-	-	-	DUF3488,DUF4129,Transglut_core
k59_174936_1	709032.Sulku_2370	2.49e-21	92.8	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42P9M@68525|delta/epsilon subdivisions,2YNH7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CZB,HAMP,MCPsignal,dCache_3
k59_937050_2	1537917.JU82_01745	7.2e-103	310.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,42MA7@68525|delta/epsilon subdivisions,2YMTP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
k59_288346_1	709032.Sulku_0766	9.01e-52	172.0	COG1729@1|root,COG1729@2|Bacteria,1NG81@1224|Proteobacteria,42R1Z@68525|delta/epsilon subdivisions,2YNY7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	repeat protein	ybgF	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_6
k59_937056_1	326298.Suden_0125	3.19e-53	177.0	COG4589@1|root,COG4589@2|Bacteria,1R34Q@1224|Proteobacteria,42QTH@68525|delta/epsilon subdivisions,2YNUH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
k59_937056_2	1165841.SULAR_10294	3.4e-61	199.0	COG1293@1|root,COG1293@2|Bacteria,1P028@1224|Proteobacteria,42MKF@68525|delta/epsilon subdivisions,2YN21@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Fibronectin fibrinogen-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
k59_48791_1	929558.SMGD1_2026	4.31e-57	194.0	COG1403@1|root,COG2227@1|root,COG1403@2|Bacteria,COG2227@2|Bacteria,1QWNW@1224|Proteobacteria,42SSA@68525|delta/epsilon subdivisions,2YSU0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1226551_1	1537917.JU82_01440	4.08e-49	161.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,42M4X@68525|delta/epsilon subdivisions,2YMCF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
k59_1226551_2	1249480.B649_05320	2.12e-56	179.0	29668@1|root,2ZTGD@2|Bacteria,1Q60I@1224|Proteobacteria,4326Q@68525|delta/epsilon subdivisions,2YSIU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_525406_1	1165841.SULAR_04402	9.53e-18	79.3	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,42MKZ@68525|delta/epsilon subdivisions,2YMGA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
k59_525406_2	1165841.SULAR_04407	5.23e-57	181.0	COG0319@1|root,COG0319@2|Bacteria,1Q9G0@1224|Proteobacteria,42SJD@68525|delta/epsilon subdivisions,2YPJA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
k59_525406_3	1165841.SULAR_04412	8.37e-32	119.0	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,42Q58@68525|delta/epsilon subdivisions,2YNDQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	K -dependent Na Ca exchanger	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
k59_937090_1	748247.AZKH_3347	1.29e-25	100.0	COG0765@1|root,COG0765@2|Bacteria,1MX2Y@1224|Proteobacteria,2VNP0@28216|Betaproteobacteria,2KVPD@206389|Rhodocyclales	206389|Rhodocyclales	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
k59_1539179_1	1249480.B649_10180	4.63e-94	283.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,42MFM@68525|delta/epsilon subdivisions,2YMJU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
k59_658884_1	929558.SMGD1_0384	2.56e-85	262.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,42M27@68525|delta/epsilon subdivisions,2YNWH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
k59_1479313_1	580332.Slit_2272	9.93e-37	129.0	COG3751@1|root,COG3751@2|Bacteria,1RD3H@1224|Proteobacteria,2VV8V@28216|Betaproteobacteria,44W5D@713636|Nitrosomonadales	28216|Betaproteobacteria	O	SMART Prolyl 4-hydroxylase alpha subunit	-	-	-	ko:K07394	-	-	-	-	ko00000	-	-	-	2OG-FeII_Oxy_3
k59_1479313_2	395494.Galf_1702	1.41e-57	183.0	COG3143@1|root,COG3143@2|Bacteria	2|Bacteria	NT	archaeal or bacterial-type flagellum-dependent cell motility	cheZ	GO:0001539,GO:0003674,GO:0003824,GO:0004721,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006928,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0032991,GO:0036211,GO:0040011,GO:0042578,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071704,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0097588,GO:0098561,GO:0140096,GO:1901564	-	ko:K03414	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheZ
k59_1654925_1	670292.JH26_04945	1.98e-09	53.5	COG3311@1|root,COG3311@2|Bacteria,1QA5W@1224|Proteobacteria,2V2MD@28211|Alphaproteobacteria,1JYPQ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	K	Prophage CP4-57 regulatory protein (AlpA)	-	-	-	-	-	-	-	-	-	-	-	-	Phage_AlpA
k59_1596145_2	1249480.B649_10505	1.04e-29	112.0	COG4784@1|root,COG4784@2|Bacteria,1QX39@1224|Proteobacteria,43DAM@68525|delta/epsilon subdivisions,2YTHR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
k59_598686_1	709032.Sulku_1471	6.7e-75	228.0	COG3658@1|root,COG3658@2|Bacteria,1N28F@1224|Proteobacteria,42RSP@68525|delta/epsilon subdivisions,2YPDS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Dihaem cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	DHC
k59_598686_2	709032.Sulku_1470	1.86e-05	45.4	COG3658@1|root,COG3658@2|Bacteria,1REFV@1224|Proteobacteria,42Q0G@68525|delta/epsilon subdivisions,2YN98@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	DHC,Ni_hydr_CYTB
k59_773098_3	1198452.Jab_2c23560	3.12e-25	103.0	COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,2VIFC@28216|Betaproteobacteria,472KY@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF1732)	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
k59_129810_1	1249480.B649_03840	4.98e-155	453.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42PTS@68525|delta/epsilon subdivisions,2YNBM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_11941_1	1192124.LIG30_4804	6.36e-21	86.3	COG0346@1|root,COG0346@2|Bacteria,1N25V@1224|Proteobacteria,2VY9T@28216|Betaproteobacteria,1K8X1@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
k59_69529_1	1249480.B649_01165	2.41e-128	382.0	COG0493@1|root,COG1894@1|root,COG0493@2|Bacteria,COG1894@2|Bacteria,1MU2H@1224|Proteobacteria,42M6X@68525|delta/epsilon subdivisions,2YM9W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COGs COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase	-	-	1.17.1.10	ko:K15022	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00377	R00134	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_20,NADH_4Fe-4S,Pyr_redox_2
k59_774512_1	709032.Sulku_0455	6.58e-123	362.0	COG0739@1|root,COG0739@2|Bacteria,1NESH@1224|Proteobacteria,42MGB@68525|delta/epsilon subdivisions,2YMT7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_1834802_1	1537917.JU82_06750	1.32e-103	323.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,42M5Q@68525|delta/epsilon subdivisions,2YM9V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
k59_69540_1	1165841.SULAR_10419	6.29e-44	145.0	COG0023@1|root,COG0023@2|Bacteria,1Q2ID@1224|Proteobacteria,42VSB@68525|delta/epsilon subdivisions,2YQ8F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Translation initiation factor SUI1	-	-	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
k59_69540_2	1165841.SULAR_10424	2.16e-43	152.0	COG0778@1|root,COG0778@2|Bacteria,1Q0G9@1224|Proteobacteria,42MWR@68525|delta/epsilon subdivisions,2YNCN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	TIGRFAM SagB-type dehydrogenase domain	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_953266_1	1177181.T9A_01157	8.4e-30	117.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RY35@1236|Gammaproteobacteria,1XNQ7@135619|Oceanospirillales	135619|Oceanospirillales	E	Aminotransferase	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_1012990_1	159087.Daro_1816	1.88e-100	293.0	COG2864@1|root,COG2864@2|Bacteria,1MXFQ@1224|Proteobacteria,2VKTA@28216|Betaproteobacteria,2KVZW@206389|Rhodocyclales	206389|Rhodocyclales	C	Prokaryotic cytochrome b561	-	-	-	ko:K00127	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
k59_1012990_2	159087.Daro_1817	1.4e-21	90.9	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,2VHPC@28216|Betaproteobacteria,2KVE1@206389|Rhodocyclales	206389|Rhodocyclales	C	Formate dehydrogenase N, transmembrane	-	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Fer4_11,Form-deh_trans
k59_953286_1	640081.Dsui_1056	2.1e-52	171.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,2VR8K@28216|Betaproteobacteria,2KW4Z@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
k59_953286_2	1304883.KI912532_gene1263	3.79e-106	310.0	COG4582@1|root,COG4582@2|Bacteria,1MW69@1224|Proteobacteria,2VIIG@28216|Betaproteobacteria,2KUR3@206389|Rhodocyclales	206389|Rhodocyclales	D	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity	zapD	-	-	ko:K18778	-	-	-	-	ko00000,ko03036	-	-	-	ZapD
k59_1714944_1	292415.Tbd_0612	1.05e-124	370.0	COG1944@1|root,COG1944@2|Bacteria,1MV7K@1224|Proteobacteria,2VHZY@28216|Betaproteobacteria	28216|Betaproteobacteria	O	YcaO cyclodehydratase, ATP-ad Mg2+-binding	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	YcaO
k59_131627_1	159087.Daro_1575	1.51e-156	459.0	COG4263@1|root,COG4263@2|Bacteria,1MVIH@1224|Proteobacteria,2VM8J@28216|Betaproteobacteria,2KVNJ@206389|Rhodocyclales	206389|Rhodocyclales	C	nitrous oxide reductase	-	-	1.7.2.4	ko:K00376	ko00910,ko01120,map00910,map01120	M00529	R02804	RC02861	ko00000,ko00001,ko00002,ko01000	-	-	-	Cupredoxin_1
k59_1247987_1	90814.KL370891_gene1167	9.16e-84	258.0	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,1RNXK@1236|Gammaproteobacteria,460AG@72273|Thiotrichales	72273|Thiotrichales	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
k59_1247992_1	1123487.KB892846_gene457	3.76e-44	158.0	COG1879@1|root,COG1879@2|Bacteria,1MUJU@1224|Proteobacteria,2VJED@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
k59_835653_1	1249480.B649_01605	2.59e-54	171.0	2BR0I@1|root,32JXY@2|Bacteria,1Q8HJ@1224|Proteobacteria,433K7@68525|delta/epsilon subdivisions,2YSTW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_69591_1	1165841.SULAR_09784	7.38e-22	92.0	COG5285@1|root,COG5285@2|Bacteria,1RC3C@1224|Proteobacteria,42R8R@68525|delta/epsilon subdivisions,2YNW8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG5285 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin	-	-	1.14.11.18	ko:K00477	ko04146,map04146	-	-	-	ko00000,ko00001,ko01000	-	-	-	PhyH
k59_69591_2	387093.SUN_0231	3.13e-48	156.0	COG0792@1|root,COG0792@2|Bacteria,1Q27V@1224|Proteobacteria,42V4E@68525|delta/epsilon subdivisions,2YQJM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
k59_1656456_1	749222.Nitsa_1028	8.55e-45	151.0	COG0735@1|root,COG0735@2|Bacteria,1N0HW@1224|Proteobacteria,42SQX@68525|delta/epsilon subdivisions,2YPH9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Belongs to the Fur family	perR	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
k59_1656456_2	1165841.SULAR_00440	1.66e-07	51.2	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,42PSG@68525|delta/epsilon subdivisions,2YMFJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
k59_423213_1	717772.THIAE_03745	5.61e-85	261.0	COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,1RMAA@1236|Gammaproteobacteria,45ZQT@72273|Thiotrichales	72273|Thiotrichales	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	-	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
k59_1186652_2	1537917.JU82_00135	2.21e-95	283.0	COG1262@1|root,COG1262@2|Bacteria,1R6GS@1224|Proteobacteria,42XMH@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Protein of unknown function (DUF1566)	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,DUF1566
k59_660960_2	156889.Mmc1_3716	6.44e-05	47.0	COG5501@1|root,COG5501@2|Bacteria,1RH4J@1224|Proteobacteria,2U72E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	sulfur oxidation protein soxY	-	-	-	ko:K17226	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxY
k59_1248038_1	401053.AciPR4_3237	5.37e-26	97.8	COG0051@1|root,COG0051@2|Bacteria,3Y4V5@57723|Acidobacteria,2JJAS@204432|Acidobacteriia	204432|Acidobacteriia	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
k59_1248038_2	1089548.KI783301_gene3350	9.17e-49	161.0	COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,4HAEN@91061|Bacilli,3WDZS@539002|Bacillales incertae sedis	91061|Bacilli	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	GO:0008150,GO:0009893,GO:0010468,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0044087,GO:0044089,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090070,GO:2000232,GO:2000234	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
k59_953370_1	1089552.KI911559_gene1459	2.21e-14	67.8	COG0278@1|root,COG0278@2|Bacteria,1MZ4V@1224|Proteobacteria,2U9QB@28211|Alphaproteobacteria,2JSSH@204441|Rhodospirillales	204441|Rhodospirillales	O	Belongs to the glutaredoxin family. Monothiol subfamily	-	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin
k59_953370_2	159087.Daro_3682	3.19e-60	187.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	XK27_07670	-	-	ko:K07397,ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	OsmC
k59_1423354_1	583345.Mmol_1705	9.88e-231	664.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,2VI4A@28216|Betaproteobacteria,2KKQ5@206350|Nitrosomonadales	206350|Nitrosomonadales	EF	PFAM Carbamoyl-phosphate synthase L chain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_1773732_1	1537917.JU82_09710	3.72e-119	343.0	COG3381@1|root,COG3381@2|Bacteria,1N4MX@1224|Proteobacteria,42RVB@68525|delta/epsilon subdivisions,2YP5X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	component of anaerobic	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_del
k59_1773732_2	709032.Sulku_0644	4.24e-156	450.0	COG1143@1|root,COG2768@1|root,COG1143@2|Bacteria,COG2768@2|Bacteria,1N7HT@1224|Proteobacteria	1224|Proteobacteria	C	4fe-4s ferredoxin, iron-sulfur binding	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
k59_1773732_3	709032.Sulku_0645	5.22e-74	224.0	COG0169@1|root,COG0169@2|Bacteria,1Q1X7@1224|Proteobacteria,431CA@68525|delta/epsilon subdivisions,2YSA4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	-	-	-	-	-	-	-	-	-	-	-	-	Shikimate_dh_N
k59_1773732_4	1249480.B649_03200	5.67e-94	276.0	2994D@1|root,2ZW7V@2|Bacteria,1Q2D1@1224|Proteobacteria,42VGB@68525|delta/epsilon subdivisions,2YQM6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1481067_1	159087.Daro_3842	1.81e-20	89.0	COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,2VH1D@28216|Betaproteobacteria,2KVKS@206389|Rhodocyclales	206389|Rhodocyclales	C	D-amino acid dehydrogenase	dadA	-	1.4.5.1	ko:K00285	ko00360,map00360	-	R01374,R09493	RC00006,RC00025	ko00000,ko00001,ko01000	-	-	-	DAO
k59_1481067_2	159087.Daro_3843	9.67e-111	338.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,2VIA1@28216|Betaproteobacteria,2KVJT@206389|Rhodocyclales	206389|Rhodocyclales	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	spoT	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
k59_247831_1	1537917.JU82_00890	4.95e-187	526.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,42MFM@68525|delta/epsilon subdivisions,2YMJU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
k59_1715035_1	1249480.B649_01130	7.08e-154	446.0	COG0464@1|root,COG0464@2|Bacteria,1N4ZI@1224|Proteobacteria,42NGJ@68525|delta/epsilon subdivisions,2YMAX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	ATPase (AAA	-	-	-	-	-	-	-	-	-	-	-	-	AAA
k59_714358_1	1002804.HBZC1_15390	2.19e-08	55.1	COG2236@1|root,COG2236@2|Bacteria,1Q1HY@1224|Proteobacteria,42TR4@68525|delta/epsilon subdivisions,2YP9B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	phosphoribosyltransferase	gpt	-	2.4.2.22	ko:K00769	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01229,R02142	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
k59_1541335_2	1125863.JAFN01000001_gene366	4.38e-53	178.0	COG0768@1|root,COG0768@2|Bacteria,1R7A0@1224|Proteobacteria,42MJC@68525|delta/epsilon subdivisions,2WJZ2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	penicillin-binding protein	pbp4	-	-	-	-	-	-	-	-	-	-	-	Transpeptidase
k59_1248125_1	396588.Tgr7_1262	1.68e-103	308.0	COG1176@1|root,COG1176@2|Bacteria,1MVGM@1224|Proteobacteria,1RNNZ@1236|Gammaproteobacteria,1WW3Y@135613|Chromatiales	135613|Chromatiales	E	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K11071,ko:K11075	ko02010,map02010	M00299,M00300	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1,3.A.1.11.2	-	-	BPD_transp_1
k59_484148_2	1249480.B649_07395	5.78e-79	241.0	COG2197@1|root,COG2197@2|Bacteria,1MXI3@1224|Proteobacteria,42WHD@68525|delta/epsilon subdivisions,2YQ36@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
k59_484148_3	1249480.B649_07400	1.48e-116	346.0	COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,42MCZ@68525|delta/epsilon subdivisions,2YNV4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	HlyD membrane-fusion protein of T1SS	-	-	-	ko:K12542	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	3.A.1.109.4,8.A.1	-	-	HlyD_3
k59_1423420_1	1122604.JONR01000020_gene486	2.18e-07	55.5	COG0745@1|root,COG0745@2|Bacteria,1RDYB@1224|Proteobacteria,1S4CZ@1236|Gammaproteobacteria,1X6HP@135614|Xanthomonadales	135614|Xanthomonadales	KT	response regulator	pilG	-	-	ko:K02657	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
k59_774688_1	522306.CAP2UW1_3121	3.85e-43	142.0	2B58A@1|root,31Y28@2|Bacteria,1RHG1@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF2502)	ypeC	-	-	-	-	-	-	-	-	-	-	-	DUF2502
k59_953438_1	246195.DNO_0446	2.23e-24	95.1	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,1SCKA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	RNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
k59_953438_2	675806.VII_003069	1.63e-72	231.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,1RN44@1236|Gammaproteobacteria,1XTHQ@135623|Vibrionales	135623|Vibrionales	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
k59_1423429_1	1537917.JU82_06750	4.03e-115	358.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,42M5Q@68525|delta/epsilon subdivisions,2YM9V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
k59_1656573_1	666681.M301_1078	1.27e-46	152.0	28WCY@1|root,2ZID9@2|Bacteria,1P4TY@1224|Proteobacteria,2W7ZQ@28216|Betaproteobacteria,2KN05@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1656573_2	666681.M301_1079	9.78e-26	103.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,2VI9P@28216|Betaproteobacteria,2KM29@206350|Nitrosomonadales	206350|Nitrosomonadales	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	-	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
k59_835789_1	880073.Calab_2707	3.77e-11	68.9	COG3852@1|root,COG4191@1|root,COG5002@1|root,COG3852@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria,2NS4C@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_247891_1	1537917.JU82_02020	3.69e-141	413.0	COG2194@1|root,COG2194@2|Bacteria,1MWS7@1224|Proteobacteria,42MI1@68525|delta/epsilon subdivisions,2YMPQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Sulfatase	eptA	-	2.7.8.43	ko:K03760	ko01503,map01503	M00722	R11555,R11556,R11557	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DUF1705,Sulfatase
k59_1186741_1	748247.AZKH_1436	2.2e-84	264.0	COG2227@1|root,COG2227@2|Bacteria,1MZEB@1224|Proteobacteria,2WGS6@28216|Betaproteobacteria,2KXMB@206389|Rhodocyclales	206389|Rhodocyclales	H	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_14,Methyltransf_23
k59_893453_1	292415.Tbd_0928	1.62e-15	75.5	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,2VQF1@28216|Betaproteobacteria,1KTIC@119069|Hydrogenophilales	119069|Hydrogenophilales	L	HTH-like domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
k59_1423446_1	159087.Daro_1759	1.56e-104	327.0	COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,2VI9F@28216|Betaproteobacteria,2KUMU@206389|Rhodocyclales	206389|Rhodocyclales	H	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
k59_1656597_1	159087.Daro_1900	1.11e-116	347.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VI4Q@28216|Betaproteobacteria,2KVHE@206389|Rhodocyclales	206389|Rhodocyclales	O	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
k59_1013295_1	436114.SYO3AOP1_1542	2.14e-101	312.0	COG4147@1|root,COG4147@2|Bacteria	2|Bacteria	S	glycolate transport	actP	GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006846,GO:0006847,GO:0006855,GO:0008028,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015103,GO:0015123,GO:0015238,GO:0015318,GO:0015654,GO:0015698,GO:0015710,GO:0015711,GO:0015718,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035433,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098656,GO:1903825,GO:1905039	-	ko:K03307,ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21,2.A.21.7	-	iB21_1397.B21_03899,iECBD_1354.ECBD_3965,iECD_1391.ECD_03939	SSF
k59_1186768_1	709032.Sulku_0705	1.69e-63	214.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42MS0@68525|delta/epsilon subdivisions,2YMTX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_714420_1	1537917.JU82_08300	2.72e-91	276.0	COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,42MF9@68525|delta/epsilon subdivisions,2YN3Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0005488,GO:0010181,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0097159,GO:0097367,GO:1901265,GO:1901363	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0663	Chorismate_synt
k59_131861_1	1121396.KB893090_gene194	2.75e-37	140.0	COG0664@1|root,COG1752@1|root,COG0664@2|Bacteria,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,42RSN@68525|delta/epsilon subdivisions,2WNDI@28221|Deltaproteobacteria,2MPUY@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin,cNMP_binding
k59_13424_1	709032.Sulku_1126	5.45e-118	373.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2YMRQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_1013330_1	1537917.JU82_08495	1.51e-29	109.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,42SR7@68525|delta/epsilon subdivisions,2YP8T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	nucleotide-binding protein implicated in inhibition of septum formation	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
k59_1013330_2	709032.Sulku_2225	4.83e-70	218.0	COG4784@1|root,COG4784@2|Bacteria,1QX39@1224|Proteobacteria,43DAM@68525|delta/epsilon subdivisions,2YTHR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
k59_187814_1	572477.Alvin_2671	3.65e-19	89.4	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,1T1G7@1236|Gammaproteobacteria,1WX1Q@135613|Chromatiales	135613|Chromatiales	KT	Fis Family	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
k59_187814_2	1189612.A33Q_2380	8.13e-13	69.7	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,47U6P@768503|Cytophagia	976|Bacteroidetes	T	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,SnoaL_3
k59_774758_1	709032.Sulku_1305	3.65e-61	200.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,42M3C@68525|delta/epsilon subdivisions,2YNGF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
k59_774758_2	998088.B565_0666	6.27e-43	143.0	COG1359@1|root,COG1359@2|Bacteria,1RH7B@1224|Proteobacteria,1S6UJ@1236|Gammaproteobacteria,1Y5Q9@135624|Aeromonadales	135624|Aeromonadales	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
k59_1161976_1	159087.Daro_1321	5.09e-127	372.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,2VH5S@28216|Betaproteobacteria,2KVN3@206389|Rhodocyclales	206389|Rhodocyclales	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
k59_1215288_1	709032.Sulku_1783	2.57e-49	173.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2YMAM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,Response_reg
k59_1215288_2	709032.Sulku_1782	5.9e-44	147.0	COG1999@1|root,COG1999@2|Bacteria,1QSGU@1224|Proteobacteria,431T6@68525|delta/epsilon subdivisions,2YS7S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
k59_576902_2	159087.Daro_3871	1.08e-69	213.0	COG3439@1|root,COG3439@2|Bacteria,1RHPD@1224|Proteobacteria,2VV5X@28216|Betaproteobacteria,2KX7Y@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
k59_576902_3	159087.Daro_3870	2.37e-27	109.0	COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,1MV6M@1224|Proteobacteria,2VIEC@28216|Betaproteobacteria,2KUEK@206389|Rhodocyclales	206389|Rhodocyclales	KL	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SWIM
k59_861365_1	387093.SUN_0587	7.28e-80	259.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,42MYN@68525|delta/epsilon subdivisions,2YMXA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	molybdopterin oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin,Molydop_binding
k59_218778_1	1249480.B649_07355	4.86e-95	281.0	COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,42M4J@68525|delta/epsilon subdivisions,2YMZ4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	ABC transporter, ATP-binding protein	lptB	-	-	ko:K01990,ko:K06861	ko02010,map02010	M00254,M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1,3.A.1	-	-	ABC_tran,BCA_ABC_TP_C
k59_1800826_1	1249480.B649_05260	3.12e-150	442.0	COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,42M9U@68525|delta/epsilon subdivisions,2YNJP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	RNA binding S1 domain protein	-	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
k59_37873_1	395494.Galf_1329	8.7e-35	125.0	COG0421@1|root,COG0421@2|Bacteria,1QUUH@1224|Proteobacteria	1224|Proteobacteria	E	cog0421, spermidine synthase	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
k59_576919_2	1249480.B649_09835	9.72e-59	185.0	COG3018@1|root,COG3018@2|Bacteria,1RGG9@1224|Proteobacteria,42P0S@68525|delta/epsilon subdivisions,2YQJK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	(Lipo)protein	-	-	-	ko:K09860	-	-	-	-	ko00000	-	-	-	LPP20
k59_1800833_1	709032.Sulku_1836	1.53e-118	348.0	COG0642@1|root,COG0642@2|Bacteria,1QZ2C@1224|Proteobacteria,42QBR@68525|delta/epsilon subdivisions,2YNQB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_2,sCache_2
k59_922470_1	1249480.B649_05385	7.97e-99	301.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2YR9K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	-	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
k59_1099108_1	1121459.AQXE01000001_gene2745	7.04e-28	116.0	COG3170@1|root,COG3170@2|Bacteria,1Q45C@1224|Proteobacteria,42Z4T@68525|delta/epsilon subdivisions,2WTRW@28221|Deltaproteobacteria,2MA4T@213115|Desulfovibrionales	28221|Deltaproteobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1684423_1	159087.Daro_1774	2.06e-90	277.0	COG1593@1|root,COG1593@2|Bacteria,1MUQE@1224|Proteobacteria,2VHK0@28216|Betaproteobacteria,2KUE4@206389|Rhodocyclales	206389|Rhodocyclales	G	Malonyl-CoA decarboxylase N-terminal domain	-	-	4.1.1.9	ko:K01578	ko00410,ko00640,ko01100,ko04146,ko04152,map00410,map00640,map01100,map04146,map04152	-	R00233	RC00040	ko00000,ko00001,ko01000	-	-	-	MCD,MCD_N
k59_1508517_1	929558.SMGD1_2841	7.03e-99	296.0	COG1397@1|root,COG1397@2|Bacteria,1PUW9@1224|Proteobacteria,42Z7N@68525|delta/epsilon subdivisions,2YR1W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
k59_389373_1	387093.SUN_0856	4.77e-52	181.0	COG1001@1|root,COG1001@2|Bacteria,1MVFP@1224|Proteobacteria,42NWX@68525|delta/epsilon subdivisions,2YR28@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Adenine deaminase C-terminal domain	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
k59_1684444_2	404589.Anae109_4259	2.18e-07	54.7	COG0810@1|root,COG0810@2|Bacteria,1N94H@1224|Proteobacteria,42V43@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
k59_1330909_1	1249480.B649_04195	9.61e-108	317.0	COG2227@1|root,COG2227@2|Bacteria,1NN3B@1224|Proteobacteria,43C3V@68525|delta/epsilon subdivisions,2YTAM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs	cmoB	-	-	ko:K15257	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_9
k59_737025_1	1249480.B649_03675	1.81e-58	201.0	COG2319@1|root,COG2319@2|Bacteria,1Q4KY@1224|Proteobacteria,42ZEF@68525|delta/epsilon subdivisions,2YR4A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_514683_3	1537917.JU82_04665	1.28e-16	79.0	COG0810@1|root,COG0810@2|Bacteria,1QAAM@1224|Proteobacteria,42X9R@68525|delta/epsilon subdivisions,2YQQ7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	TonB C terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_2
k59_389405_1	1132855.KB913035_gene395	1.36e-08	55.5	COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,2VH7F@28216|Betaproteobacteria,2KKHQ@206350|Nitrosomonadales	206350|Nitrosomonadales	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
k59_389405_2	225849.swp_4029	1.23e-38	138.0	COG1278@1|root,COG1463@1|root,COG1278@2|Bacteria,COG1463@2|Bacteria,1RHH6@1224|Proteobacteria,1S74Q@1236|Gammaproteobacteria,2QBT4@267890|Shewanellaceae	1236|Gammaproteobacteria	Q	Protein of unknown function (DUF3465)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3465
k59_576985_1	1165841.SULAR_06848	3.51e-54	187.0	COG0457@1|root,COG0457@2|Bacteria,1MXK4@1224|Proteobacteria,42PK9@68525|delta/epsilon subdivisions,2YNXX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
k59_577005_1	709032.Sulku_1038	1.59e-66	207.0	COG1477@1|root,COG1477@2|Bacteria	2|Bacteria	H	protein flavinylation	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
k59_922581_1	323261.Noc_1697	3.2e-45	164.0	COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,1RR7X@1236|Gammaproteobacteria,1WW9A@135613|Chromatiales	135613|Chromatiales	G	PFAM carbohydrate kinase	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
k59_861495_1	395494.Galf_2123	1.67e-92	284.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,2VHWX@28216|Betaproteobacteria,44VEU@713636|Nitrosomonadales	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k59_162164_1	1537917.JU82_08665	1.41e-40	145.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,42M7A@68525|delta/epsilon subdivisions,2YNCK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k59_162164_2	1249480.B649_10360	3.88e-24	94.7	COG4969@1|root,COG4969@2|Bacteria,1QZMY@1224|Proteobacteria,42WPI@68525|delta/epsilon subdivisions,2YQFF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
k59_1745616_1	326297.Sama_2543	9.73e-54	184.0	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,2QDMN@267890|Shewanellaceae	1236|Gammaproteobacteria	Q	Tripartite ATP-independent periplasmic transporter, DctM component	gtrB	-	-	-	-	-	-	-	-	-	-	-	DctM
k59_389441_1	1249480.B649_01055	1.69e-84	256.0	COG1344@1|root,COG1344@2|Bacteria,1P7ZB@1224|Proteobacteria,42QS1@68525|delta/epsilon subdivisions,2YNAV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	flaC	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
k59_1049248_3	709032.Sulku_1221	1.67e-54	177.0	2A4Y3@1|root,30TJW@2|Bacteria,1PDG3@1224|Proteobacteria,42X3Z@68525|delta/epsilon subdivisions,2YQTE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_695618_1	709032.Sulku_1639	3.45e-52	186.0	COG0784@1|root,COG2198@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,43BU6@68525|delta/epsilon subdivisions,2YTGC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_9,Response_reg
k59_922639_1	709032.Sulku_2236	2.97e-16	74.3	COG2165@1|root,COG2165@2|Bacteria,1PTBM@1224|Proteobacteria,42XHE@68525|delta/epsilon subdivisions,2YQVZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
k59_922639_2	1249480.B649_10575	3.42e-44	149.0	2AJ1F@1|root,319JK@2|Bacteria,1Q2YN@1224|Proteobacteria,42WGN@68525|delta/epsilon subdivisions,2YQK8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_451453_1	709032.Sulku_1357	2.92e-103	315.0	COG0204@1|root,COG0477@1|root,COG0204@2|Bacteria,COG2814@2|Bacteria,1MWDY@1224|Proteobacteria,43BJD@68525|delta/epsilon subdivisions,2YNEB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	2-acylglycerophosphoethanolamine acyltransferase	aas	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
k59_1162189_1	1537917.JU82_02040	1.63e-120	374.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42M0A@68525|delta/epsilon subdivisions,2YNJ1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	cznA	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
k59_632732_2	709032.Sulku_1757	9.76e-76	251.0	COG1305@1|root,COG4196@1|root,COG1305@2|Bacteria,COG4196@2|Bacteria,1MVAG@1224|Proteobacteria,42P26@68525|delta/epsilon subdivisions,2YN89@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Putative amidoligase enzyme (DUF2126)	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,DUF2126,Transglut_core
k59_922658_2	1249480.B649_11415	1.49e-17	79.3	2CCD9@1|root,32NJ2@2|Bacteria,1Q3UE@1224|Proteobacteria,42XU5@68525|delta/epsilon subdivisions,2YQSW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	YtkA-like	-	-	-	-	-	-	-	-	-	-	-	-	YtkA
k59_861546_1	1537915.JU57_09545	6.23e-120	373.0	COG1234@1|root,COG2203@1|root,COG2206@1|root,COG3437@1|root,COG1234@2|Bacteria,COG2203@2|Bacteria,COG2206@2|Bacteria,COG3437@2|Bacteria,1MV37@1224|Proteobacteria,42N4N@68525|delta/epsilon subdivisions,2YNBF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	cAMP phosphodiesterases class-II	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HD,HD_5,Lactamase_B_2,PDEase_II
k59_1162197_1	1304883.KI912532_gene1717	1.35e-37	140.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,2VIE0@28216|Betaproteobacteria,2KUDK@206389|Rhodocyclales	206389|Rhodocyclales	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_5
k59_1162197_2	983917.RGE_32990	5.51e-18	77.4	COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,2VSJ2@28216|Betaproteobacteria,1KM4W@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	ybaB	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
k59_987057_1	1182590.BN5_00204	3.68e-93	287.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,1RMA3@1236|Gammaproteobacteria,1YE80@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
k59_579789_1	159087.Daro_0275	7.74e-57	184.0	COG0850@1|root,COG0850@2|Bacteria,1RHVN@1224|Proteobacteria,2VNVN@28216|Betaproteobacteria,2KWD0@206389|Rhodocyclales	206389|Rhodocyclales	D	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization	minC	-	-	ko:K03610	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinC_C,MinC_N
k59_579789_2	762376.AXYL_00977	5.93e-12	64.3	COG2894@1|root,COG2894@2|Bacteria,1MUEU@1224|Proteobacteria,2VJFP@28216|Betaproteobacteria,3T1M0@506|Alcaligenaceae	28216|Betaproteobacteria	D	Belongs to the ParA family	minD	-	-	ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
k59_1283966_1	709032.Sulku_1075	3.34e-25	95.5	2BPZI@1|root,32ITJ@2|Bacteria,1PBV9@1224|Proteobacteria,42VR5@68525|delta/epsilon subdivisions,2YQJA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1283966_2	1537917.JU82_04980	9.79e-89	271.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,42N4K@68525|delta/epsilon subdivisions,2YMXB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
k59_864159_1	159087.Daro_0030	4.76e-74	242.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,2VIDI@28216|Betaproteobacteria,2KV2P@206389|Rhodocyclales	206389|Rhodocyclales	T	Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k59_1101734_1	1165841.SULAR_05813	9.19e-48	164.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,42M2M@68525|delta/epsilon subdivisions,2YMS3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
k59_1334024_1	717772.THIAE_07685	4.89e-63	211.0	COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,1RNWD@1236|Gammaproteobacteria,4600N@72273|Thiotrichales	72273|Thiotrichales	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
k59_1051820_1	709032.Sulku_0921	1.66e-213	622.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2YMA1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
k59_1629839_1	709032.Sulku_2469	1.44e-66	222.0	COG4206@1|root,COG4206@2|Bacteria,1QUGQ@1224|Proteobacteria,42PHJ@68525|delta/epsilon subdivisions,2YNKV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_1334040_2	1167006.UWK_03301	3.37e-65	205.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,42PYJ@68525|delta/epsilon subdivisions,2WKHY@28221|Deltaproteobacteria,2MJ28@213118|Desulfobacterales	28221|Deltaproteobacteria	V	PFAM ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_221527_1	153948.NAL212_0275	4.4e-77	243.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,2VI3A@28216|Betaproteobacteria,371YV@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
k59_221527_2	317025.Tcr_1628	1.23e-81	256.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RP7E@1236|Gammaproteobacteria,45ZRF@72273|Thiotrichales	72273|Thiotrichales	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
k59_739328_1	1355368.JART01000027_gene330	1.81e-53	183.0	COG3174@1|root,COG3174@2|Bacteria,1RA19@1224|Proteobacteria,42PB8@68525|delta/epsilon subdivisions,2YNQN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function (DUF4010)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010
k59_739328_2	398767.Glov_0188	7.74e-27	104.0	296ZZ@1|root,2ZU8H@2|Bacteria,1RED2@1224|Proteobacteria,42RDU@68525|delta/epsilon subdivisions,2WPHV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_579915_1	1249480.B649_03830	5.77e-82	250.0	COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,42QG8@68525|delta/epsilon subdivisions,2YNS2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Succinylglutamate desuccinylase	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
k59_579915_2	1249480.B649_03825	5.57e-69	216.0	COG2307@1|root,COG2307@2|Bacteria,1NMSC@1224|Proteobacteria,42V9T@68525|delta/epsilon subdivisions,2YQAK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
k59_1334071_1	709032.Sulku_1019	4.6e-151	436.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,42MXQ@68525|delta/epsilon subdivisions,2YM9P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0098	PALP,Thr_synth_N
k59_1334078_1	709032.Sulku_0938	1.59e-96	293.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,42M28@68525|delta/epsilon subdivisions,2YMFV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
k59_453993_1	1249480.B649_11215	3.92e-106	313.0	COG0760@1|root,COG0760@2|Bacteria,1N20M@1224|Proteobacteria,42SXW@68525|delta/epsilon subdivisions,2YPHS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase_2,SurA_N,SurA_N_3
k59_1101837_1	159087.Daro_0608	1.45e-119	355.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,2VJ86@28216|Betaproteobacteria,2KUHV@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
k59_864304_1	1537917.JU82_10620	3.05e-102	318.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,42MW3@68525|delta/epsilon subdivisions,2YMT6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
k59_1218244_1	1249480.B649_08660	4.51e-147	427.0	COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,42QG6@68525|delta/epsilon subdivisions,2YMUP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	na -driven multidrug efflux	-	-	-	-	-	-	-	-	-	-	-	-	MatE
k59_1394460_1	1537917.JU82_04535	6.97e-31	118.0	COG0477@1|root,COG2814@2|Bacteria,1QRUM@1224|Proteobacteria,42MFJ@68525|delta/epsilon subdivisions,2YMW9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EGP	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_1394460_2	1249480.B649_08675	4.58e-24	94.7	COG1334@1|root,COG1334@2|Bacteria,1NH9T@1224|Proteobacteria,42X2H@68525|delta/epsilon subdivisions,2YR05@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	FlaG protein	-	-	-	ko:K06603	-	-	-	-	ko00000,ko02035	-	-	-	FlaG
k59_925771_1	1249480.B649_00995	4.01e-97	295.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42N0C@68525|delta/epsilon subdivisions,2YMDS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
k59_1748577_1	1537917.JU82_06925	1e-101	305.0	COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,42MVB@68525|delta/epsilon subdivisions,2YNU4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	O-acetylhomoserine sulfhydrylase	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
k59_164586_1	583345.Mmol_0722	4.69e-155	445.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,2VIWB@28216|Betaproteobacteria,2KKTV@206350|Nitrosomonadales	206350|Nitrosomonadales	C	TIGRFAM cytochrome c oxidase, cbb3-type, subunit I	-	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
k59_810309_1	1537917.JU82_08460	1.05e-121	358.0	COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,42MI0@68525|delta/epsilon subdivisions,2YMAS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Small subunit	hydA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.12.5.1	ko:K05927	-	-	-	-	ko00000,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6,TAT_signal
k59_1164796_1	159087.Daro_3689	2.81e-130	379.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,2VHNC@28216|Betaproteobacteria,2KV1D@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
k59_277489_1	1242864.D187_007102	1.12e-05	55.1	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria	1224|Proteobacteria	P	Receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_1460168_2	159087.Daro_2670	3.27e-73	220.0	COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,2VSDF@28216|Betaproteobacteria,2KWMH@206389|Rhodocyclales	206389|Rhodocyclales	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
k59_1687237_2	1537917.JU82_03900	1.17e-87	265.0	COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,42QA8@68525|delta/epsilon subdivisions,2YNH6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_3
k59_1164824_1	1249480.B649_10355	1.13e-77	234.0	COG4969@1|root,COG4969@2|Bacteria,1QZMZ@1224|Proteobacteria,42U5N@68525|delta/epsilon subdivisions,2YPXN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
k59_40613_1	1249480.B649_04850	3.05e-118	364.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,42MD4@68525|delta/epsilon subdivisions,2YNMI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	PFAM Helicase conserved C-terminal domain	hrpB	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
k59_1218318_1	1537917.JU82_11465	1.53e-117	343.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,42NQB@68525|delta/epsilon subdivisions,2YMSA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	iIT341.HP0961	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
k59_1218318_2	709032.Sulku_0824	3.8e-65	204.0	COG1226@1|root,COG1226@2|Bacteria,1R0RZ@1224|Proteobacteria,42UWU@68525|delta/epsilon subdivisions,2YQ24@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	TrkA-N domain	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	TrkA_C,TrkA_N
k59_1101933_1	1249480.B649_05075	6.09e-113	348.0	COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,42M43@68525|delta/epsilon subdivisions,2YM8G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the aconitase IPM isomerase family	acnB	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0045333,GO:0046395,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072329,GO:0072350,GO:0097159,GO:1901363,GO:1901575	4.2.1.3,4.2.1.99	ko:K01682	ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173	R01324,R01325,R01900,R04425	RC00497,RC00498,RC00618,RC01153	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_2_N,Aconitase_B_N
k59_303877_1	857087.Metme_4243	4.76e-05	44.3	28K33@1|root,2Z9SC@2|Bacteria,1Q1U9@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_303877_2	312284.A20C1_09279	6.12e-24	103.0	COG0673@1|root,COG0673@2|Bacteria,2GK0F@201174|Actinobacteria,3UWQM@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	dehydrogenases and related proteins	-	-	1.1.1.361	ko:K18652	-	-	-	-	ko00000,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
k59_247185_1	1537917.JU82_01235	2.6e-62	192.0	COG0818@1|root,COG0818@2|Bacteria,1Q5TS@1224|Proteobacteria,42SZA@68525|delta/epsilon subdivisions,2YSYV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Recycling of diacylglycerol produced during the turnover of membrane phospholipid	-	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
k59_303880_2	159087.Daro_2862	2.63e-62	196.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,2VIKC@28216|Betaproteobacteria,2KUNB@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_17
k59_1247322_1	1304883.KI912532_gene284	5.8e-110	324.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,2VHHG@28216|Betaproteobacteria,2KUIY@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k59_1302537_1	1217718.ALOU01000040_gene127	1.79e-65	212.0	COG1089@1|root,COG1089@2|Bacteria,1MUX0@1224|Proteobacteria,2VIBX@28216|Betaproteobacteria,1K0D3@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
k59_1302537_2	296591.Bpro_3995	3.12e-41	148.0	COG2244@1|root,COG2244@2|Bacteria,1MXWW@1224|Proteobacteria,2VNZP@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Pfam Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3
k59_1129324_1	1316932.MHH_c23490	3.53e-11	66.2	COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,1RPYF@1236|Gammaproteobacteria,1Y6XT@135625|Pasteurellales	135625|Pasteurellales	P	High-affinity zinc uptake system membrane protein ZnuB	znuB	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0010035,GO:0010038,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0071944	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
k59_1714459_1	1249480.B649_07410	4.46e-115	343.0	COG1538@1|root,COG1538@2|Bacteria,1MYX2@1224|Proteobacteria,42MHZ@68525|delta/epsilon subdivisions,2YNGC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	Outer membrane efflux protein	-	-	-	ko:K12543	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	1.B.17,3.A.1.109.4	-	-	OEP,OmpA,TSP_3
k59_69221_1	709032.Sulku_0659	5.66e-105	320.0	COG2199@1|root,COG3706@2|Bacteria,1NECV@1224|Proteobacteria,42PZK@68525|delta/epsilon subdivisions,2YT9R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_69221_2	1249480.B649_03275	2.16e-76	244.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,42KZ7@68525|delta/epsilon subdivisions,2YMB1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iIT341.HP1532	GATase_6,SIS
k59_1834284_1	351348.Maqu_2513	2.86e-12	65.5	COG1028@1|root,COG1028@2|Bacteria,1MUAY@1224|Proteobacteria,1S1XJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k59_952808_1	1042377.AFPJ01000038_gene1106	1.97e-07	52.8	COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,1S62H@1236|Gammaproteobacteria,4679N@72275|Alteromonadaceae	1236|Gammaproteobacteria	U	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA	secB	GO:0002790,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006605,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0034613,GO:0042886,GO:0043952,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051082,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0072321	-	ko:K03071	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03110	3.A.5	-	-	SecB
k59_952808_2	90813.JQMT01000001_gene1904	3.54e-24	94.0	COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,1SCA2@1236|Gammaproteobacteria,4614I@72273|Thiotrichales	72273|Thiotrichales	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	-	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
k59_422732_1	1249480.B649_04165	2e-116	338.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,42N3Z@68525|delta/epsilon subdivisions,2YMT4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
k59_1186209_1	240015.ACP_0622	9.91e-31	115.0	COG1137@1|root,COG1137@2|Bacteria,3Y2MC@57723|Acidobacteria,2JHPV@204432|Acidobacteriia	204432|Acidobacteriia	S	ABC transporter	-	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
k59_1186209_2	1347368.HG964403_gene4365	1.37e-10	62.4	COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,4HFX9@91061|Bacilli,1ZFW8@1386|Bacillus	91061|Bacilli	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
k59_835156_1	1165841.SULAR_01360	4.46e-123	383.0	COG0755@1|root,COG1333@1|root,COG0755@2|Bacteria,COG1333@2|Bacteria,1RG0A@1224|Proteobacteria,42N37@68525|delta/epsilon subdivisions,2YMXW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Cytochrome c biogenesis protein	ccsBA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
k59_12851_1	709032.Sulku_1387	2.15e-80	255.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,42PUI@68525|delta/epsilon subdivisions,2YN3E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	PFAM TrkA-N domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2,TrkA_N
k59_1540638_2	709032.Sulku_1418	3.84e-118	340.0	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,42MKZ@68525|delta/epsilon subdivisions,2YMGA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
k59_952850_1	1304883.KI912532_gene223	1.22e-120	360.0	COG1274@1|root,COG1274@2|Bacteria,1MX3C@1224|Proteobacteria,2VINZ@28216|Betaproteobacteria,2KV5X@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
k59_422761_1	1523503.JPMY01000007_gene361	2.45e-25	107.0	COG3156@1|root,COG3156@2|Bacteria,1RBNV@1224|Proteobacteria,1S5US@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	COG3156 Type II secretory pathway, component PulK	xcpX	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
k59_69275_1	749222.Nitsa_0960	8.48e-62	213.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2YNMM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.6,3.6.3.8	ko:K01535,ko:K01537	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.3.2,3.A.3.3	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
k59_1361846_2	1249480.B649_02245	4.81e-37	134.0	COG0618@1|root,COG0618@2|Bacteria,1RADZ@1224|Proteobacteria,43DQA@68525|delta/epsilon subdivisions,2YT8A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	DHH family	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
k59_483558_1	1165841.SULAR_00505	3.5e-143	419.0	COG0348@1|root,COG0348@2|Bacteria,1N605@1224|Proteobacteria,42XAR@68525|delta/epsilon subdivisions,2YR2P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CP	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
k59_12906_1	159087.Daro_2935	3.51e-200	566.0	COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,2VHA5@28216|Betaproteobacteria,2KUIN@206389|Rhodocyclales	206389|Rhodocyclales	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
k59_835256_1	1249480.B649_07280	7.16e-36	132.0	COG2199@1|root,COG3706@2|Bacteria,1Q5A3@1224|Proteobacteria,430W0@68525|delta/epsilon subdivisions,2YRZB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_363479_1	709032.Sulku_0137	2.15e-28	113.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,42ND6@68525|delta/epsilon subdivisions,2YN5S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
k59_363479_2	709032.Sulku_0138	2e-188	528.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,42M0M@68525|delta/epsilon subdivisions,2YMCK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the SIS family. GutQ KpsF subfamily	kpsF	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
k59_363479_3	709032.Sulku_0139	5.38e-31	116.0	COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,42NI7@68525|delta/epsilon subdivisions,2YMH9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_1835835_2	572480.Arnit_1014	2.52e-61	204.0	COG2759@1|root,COG2759@2|Bacteria,1MUR8@1224|Proteobacteria,42MKE@68525|delta/epsilon subdivisions,2YN6Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
k59_1598365_1	697282.Mettu_2084	1.35e-22	93.6	COG5616@1|root,COG5616@2|Bacteria,1NSKC@1224|Proteobacteria,1T49A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1598365_2	640081.Dsui_0644	2.82e-58	196.0	COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,2VGZE@28216|Betaproteobacteria,2KV0T@206389|Rhodocyclales	206389|Rhodocyclales	IQ	AMP-binding enzyme	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
k59_1424253_1	709032.Sulku_2450	8.43e-81	266.0	COG0517@1|root,COG2202@1|root,COG5001@1|root,COG0517@2|Bacteria,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YMHP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF,PAS_4
k59_661916_1	1249480.B649_02725	1.31e-24	96.3	COG1585@1|root,COG1585@2|Bacteria,1QAJG@1224|Proteobacteria,43AB2@68525|delta/epsilon subdivisions,2YQRB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	OU	Membrane protein implicated in regulation of membrane protease activity	-	-	-	ko:K07340	-	-	-	-	ko00000	-	-	-	NfeD
k59_661916_2	1537917.JU82_03300	8.79e-72	218.0	COG3012@1|root,COG3012@2|Bacteria,1Q5V3@1224|Proteobacteria,42UFW@68525|delta/epsilon subdivisions,2YPTX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	SEC-C motif	-	-	-	ko:K09858	-	-	-	-	ko00000	-	-	-	SEC-C
k59_775328_1	387093.SUN_1678	6.75e-50	173.0	COG4972@1|root,COG4972@2|Bacteria,1QA6M@1224|Proteobacteria,42NDB@68525|delta/epsilon subdivisions,2YMP2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Pilus assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_775328_2	387093.SUN_1679	2.2e-126	366.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,42MUR@68525|delta/epsilon subdivisions,2YMG3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
k59_1363160_1	1249480.B649_05020	9.66e-116	337.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,42N0M@68525|delta/epsilon subdivisions,2YT9X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules	xerH	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_1363160_2	1249480.B649_05015	3.22e-78	241.0	2AGMT@1|root,316V3@2|Bacteria,1PY20@1224|Proteobacteria,42NND@68525|delta/epsilon subdivisions,2YMQB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	pgbB	-	-	-	-	-	-	-	-	-	-	-	PGBA_C,PQQ_2
k59_13963_1	583345.Mmol_1333	8.31e-93	285.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2VP8B@28216|Betaproteobacteria,2KM89@206350|Nitrosomonadales	206350|Nitrosomonadales	EH	Anthranilate synthase component I	-	-	2.6.1.85	ko:K01665	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
k59_894139_2	1249480.B649_09065	6.97e-85	268.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2YMMU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_1774501_1	709032.Sulku_0758	2.43e-105	310.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,42N8B@68525|delta/epsilon subdivisions,2YMRV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
k59_248614_2	1249480.B649_09260	9.5e-05	46.6	COG1305@1|root,COG1305@2|Bacteria,1MVMI@1224|Proteobacteria,42PJK@68525|delta/epsilon subdivisions,2YNSY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Bacterial transglutaminase-like N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
k59_13989_1	159087.Daro_1802	1.66e-51	176.0	COG0642@1|root,COG3850@1|root,COG2205@2|Bacteria,COG3850@2|Bacteria,1N58A@1224|Proteobacteria,2VHVP@28216|Betaproteobacteria,2KUT7@206389|Rhodocyclales	206389|Rhodocyclales	T	Histidine kinase	yfhK	-	2.7.13.3	ko:K07711	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
k59_424021_1	196162.Noca_4181	9.8e-10	62.4	COG1089@1|root,COG1089@2|Bacteria,2GNMA@201174|Actinobacteria,4DPK0@85009|Propionibacteriales	201174|Actinobacteria	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
k59_1542262_1	944547.ABLL_1400	2.45e-41	157.0	COG2202@1|root,COG4191@1|root,COG5001@1|root,COG5002@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,COG5001@2|Bacteria,COG5002@2|Bacteria,1MU2C@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GGDEF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9
k59_1774524_1	709032.Sulku_2262	1.55e-43	157.0	COG1538@1|root,COG1538@2|Bacteria,1Q5X2@1224|Proteobacteria,43200@68525|delta/epsilon subdivisions,2YS78@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_485006_1	1304883.KI912532_gene821	1.06e-114	337.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,2VH9B@28216|Betaproteobacteria,2KV12@206389|Rhodocyclales	206389|Rhodocyclales	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
k59_485006_2	1304883.KI912532_gene820	5.39e-05	44.3	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,2VI8N@28216|Betaproteobacteria,2KUE2@206389|Rhodocyclales	206389|Rhodocyclales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_1303729_2	266117.Rxyl_1929	3.69e-94	301.0	COG1067@1|root,COG1067@2|Bacteria,2H2TE@201174|Actinobacteria	201174|Actinobacteria	O	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
k59_775368_2	326298.Suden_0647	8.41e-80	246.0	2C2AA@1|root,2ZAYY@2|Bacteria,1RD8I@1224|Proteobacteria,42N13@68525|delta/epsilon subdivisions,2YN8K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	TraT complement resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	TraT
k59_1774540_1	1165841.SULAR_09324	3.54e-93	285.0	2C3QV@1|root,2Z7YP@2|Bacteria,1MXAM@1224|Proteobacteria,42QBG@68525|delta/epsilon subdivisions,2YNTS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
k59_1363243_1	1165096.ARWF01000001_gene1636	7.37e-66	203.0	COG1795@1|root,COG1795@2|Bacteria,1MWYS@1224|Proteobacteria,2VNIQ@28216|Betaproteobacteria,2KKMJ@206350|Nitrosomonadales	206350|Nitrosomonadales	S	PFAM Formaldehyde-activating enzyme (Fae)	-	-	-	-	-	-	-	-	-	-	-	-	Fae
k59_1014281_1	159087.Daro_0603	4.42e-40	142.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,2VJ4F@28216|Betaproteobacteria,2KUDA@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
k59_1014281_2	1121035.AUCH01000005_gene155	1.58e-37	132.0	COG0406@1|root,COG0406@2|Bacteria,1NPC4@1224|Proteobacteria,2VQTE@28216|Betaproteobacteria,2KWHE@206389|Rhodocyclales	206389|Rhodocyclales	G	Belongs to the phosphoglycerate mutase family	gpmB	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
k59_662032_1	709032.Sulku_0321	2.23e-34	126.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
k59_424092_1	709032.Sulku_2336	9.74e-22	95.9	COG2194@1|root,COG2194@2|Bacteria,1MWS7@1224|Proteobacteria,42MI1@68525|delta/epsilon subdivisions,2YMPQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Sulfatase	eptA	-	2.7.8.43	ko:K03760	ko01503,map01503	M00722	R11555,R11556,R11557	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DUF1705,Sulfatase
k59_1542360_1	305700.B447_09128	1.71e-106	315.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,2VHHG@28216|Betaproteobacteria,2KUIY@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k59_601380_1	760154.Sulba_1561	2.12e-16	74.3	2BQTV@1|root,32JQM@2|Bacteria,1PDND@1224|Proteobacteria,42XBT@68525|delta/epsilon subdivisions,2YQFS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_364618_1	1537917.JU82_10885	1.35e-148	421.0	COG0852@1|root,COG0852@2|Bacteria,1MX4B@1224|Proteobacteria,42NAR@68525|delta/epsilon subdivisions,2YN6R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
k59_836686_1	583345.Mmol_0719	5e-44	150.0	COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,2VHGS@28216|Betaproteobacteria,2KMD1@206350|Nitrosomonadales	206350|Nitrosomonadales	C	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex	-	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
k59_836686_2	583345.Mmol_0720	7.56e-22	85.1	COG4736@1|root,COG4736@2|Bacteria	2|Bacteria	O	Cbb3-type cytochrome oxidase	ccoQ	-	-	ko:K00407	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixQ
k59_836686_3	740709.A10D4_02142	3e-16	76.3	COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,1RPU6@1236|Gammaproteobacteria,2QFA9@267893|Idiomarinaceae	1236|Gammaproteobacteria	C	Cytochrome C oxidase, mono-heme subunit/FixO	ccoO	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
k59_424128_1	1537917.JU82_02630	4.73e-64	199.0	COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,42SB8@68525|delta/epsilon subdivisions,2YPI9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA	gidB	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
k59_894275_1	1120999.JONM01000005_gene3908	5.47e-92	287.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,2VI5B@28216|Betaproteobacteria,2KU4G@206351|Neisseriales	206351|Neisseriales	NT	Chemotaxis protein CheA	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
k59_70276_1	1249480.B649_09905	4.46e-118	345.0	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,42MFN@68525|delta/epsilon subdivisions,2YNDN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
k59_70276_2	1227268.HMPREF1552_00835	4.19e-07	50.8	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	rgpB	-	-	ko:K12997	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT2	-	Glycos_transf_2
k59_775456_1	1537917.JU82_10860	5.85e-14	69.7	COG0648@1|root,COG0648@2|Bacteria,1MX4Y@1224|Proteobacteria,42MYE@68525|delta/epsilon subdivisions,2YMF4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
k59_775456_2	1249480.B649_01120	1.44e-67	217.0	COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,42N9J@68525|delta/epsilon subdivisions,2YMC3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Long-chain fatty acid transport protein	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k59_305488_1	1537917.JU82_03735	1.85e-120	348.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,42M61@68525|delta/epsilon subdivisions,2YM9D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the KdsA family	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
k59_188518_1	709032.Sulku_0516	2.28e-178	510.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,42M6V@68525|delta/epsilon subdivisions,2YM9I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k59_954381_1	305900.GV64_16415	1.59e-39	145.0	COG1305@1|root,COG1305@2|Bacteria,1MVV3@1224|Proteobacteria,1RRIA@1236|Gammaproteobacteria,1XI8H@135619|Oceanospirillales	135619|Oceanospirillales	E	7 transmembrane helices usually fused to an inactive transglutaminase	-	-	-	-	-	-	-	-	-	-	-	-	7TM_transglut,Transglut_i_TM
k59_1860979_1	1249480.B649_03675	9.83e-61	208.0	COG2319@1|root,COG2319@2|Bacteria,1Q4KY@1224|Proteobacteria,42ZEF@68525|delta/epsilon subdivisions,2YR4A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1154849_1	555778.Hneap_1395	3.01e-71	225.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,1TJ1K@1236|Gammaproteobacteria,1WXNM@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_1154849_2	412597.AEPN01000015_gene1227	2.06e-11	67.8	COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,2TQWS@28211|Alphaproteobacteria,2PUFG@265|Paracoccus	28211|Alphaproteobacteria	E	Homoserine dehydrogenase	hom	GO:0003674,GO:0003824,GO:0004412,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
k59_268184_1	709032.Sulku_0798	7.57e-72	231.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,42NKZ@68525|delta/epsilon subdivisions,2YMT9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	RND efflux system, outer membrane lipoprotein	cmeC	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
k59_155737_1	948106.AWZT01000092_gene529	3.65e-09	62.8	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria,1KIH6@119060|Burkholderiaceae	28216|Betaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_9,Response_reg
k59_268193_1	1537917.JU82_03055	3.89e-160	464.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,42MDZ@68525|delta/epsilon subdivisions,2YMJR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaGprimase_HBD,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
k59_624561_1	1357423.S5MBP4_9CAUD	3.86e-82	264.0	4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses  no RNA stage,4QRFY@28883|Caudovirales	28883|Caudovirales	S	Ribonucleotide reductase, barrel domain	-	GO:0003674,GO:0003824,GO:0004748,GO:0008150,GO:0008152,GO:0016491,GO:0016725,GO:0016728,GO:0055114,GO:0061731	-	-	-	-	-	-	-	-	-	-	-
k59_268199_1	1125718.HMPREF1318_0917	1.1e-12	73.2	29Y73@1|root,30K0P@2|Bacteria,2HJIM@201174|Actinobacteria,4D3N4@85005|Actinomycetales	201174|Actinobacteria	S	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_4
k59_730093_1	944547.ABLL_2625	5.55e-44	157.0	COG0577@1|root,COG0577@2|Bacteria,1P00G@1224|Proteobacteria,42P0D@68525|delta/epsilon subdivisions,2YMKU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	ABC transporter permease	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
k59_383208_1	1249480.B649_00045	2.2e-89	279.0	COG0784@1|root,COG5001@1|root,COG0784@2|Bacteria,COG5001@2|Bacteria,1MUNI@1224|Proteobacteria	1224|Proteobacteria	T	COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3369,EAL,GGDEF,Response_reg
k59_624596_1	159087.Daro_3532	4.49e-64	199.0	COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,2VR6F@28216|Betaproteobacteria,2KWMZ@206389|Rhodocyclales	206389|Rhodocyclales	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
k59_88393_2	1249480.B649_03565	1.25e-09	58.5	COG3203@1|root,COG3203@2|Bacteria,1R1K3@1224|Proteobacteria,43DCJ@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	outer membrane porin, OprD family	-	-	-	-	-	-	-	-	-	-	-	-	OprD
k59_443986_1	1304883.KI912532_gene1024	5.56e-24	94.7	COG3088@1|root,COG3088@2|Bacteria,1MZZ5@1224|Proteobacteria,2VU7C@28216|Betaproteobacteria,2KX2W@206389|Rhodocyclales	206389|Rhodocyclales	P	subunit of a heme lyase	-	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
k59_443986_2	1304883.KI912532_gene1023	3.95e-36	130.0	COG4235@1|root,COG4235@2|Bacteria,1MY4J@1224|Proteobacteria,2VQ05@28216|Betaproteobacteria,2KW83@206389|Rhodocyclales	206389|Rhodocyclales	O	Cytochrome c-type biogenesis protein	-	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	TPR_16
k59_624599_1	748247.AZKH_0562	8.17e-43	154.0	COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,2VI9T@28216|Betaproteobacteria,2KVW2@206389|Rhodocyclales	206389|Rhodocyclales	EQ	Hydantoinase B/oxoprolinase	acxB	-	6.4.1.6	ko:K10854	-	-	-	-	ko00000,ko01000	-	-	-	Hydantoinase_B
k59_624599_2	159087.Daro_1020	2.36e-124	353.0	COG4647@1|root,COG4647@2|Bacteria,1N485@1224|Proteobacteria,2VK8X@28216|Betaproteobacteria,2KUTV@206389|Rhodocyclales	206389|Rhodocyclales	Q	Acetone carboxylase gamma subunit	acxC	-	6.4.1.6	ko:K10856	-	-	-	-	ko00000,ko01000	-	-	-	Acetone_carb_G
k59_977829_1	1537917.JU82_07750	4.75e-186	533.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,42KZ7@68525|delta/epsilon subdivisions,2YMB1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iIT341.HP1532	GATase_6,SIS
k59_855510_2	1249480.B649_01845	2.08e-65	211.0	COG2199@1|root,COG3706@2|Bacteria,1MWHH@1224|Proteobacteria,42RQ2@68525|delta/epsilon subdivisions,2YP69@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG2199 FOG GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,GGDEF
k59_570892_1	709032.Sulku_1162	2.9e-120	344.0	COG4951@1|root,COG4951@2|Bacteria,1PC94@1224|Proteobacteria,42NUB@68525|delta/epsilon subdivisions,2YMWW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Domain of unknown function (DUF1882)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1882
k59_570892_2	1249480.B649_04950	2.28e-18	84.0	COG3087@1|root,COG3147@1|root,COG3087@2|Bacteria,COG3147@2|Bacteria,1MYFG@1224|Proteobacteria,42X9Q@68525|delta/epsilon subdivisions,2YQPX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Sporulation related domain	-	-	-	ko:K03749	-	-	-	-	ko00000	-	-	-	SPOR
k59_1677572_2	709032.Sulku_2255	8.53e-122	351.0	COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,42N66@68525|delta/epsilon subdivisions,2YMY7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate	ate	-	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	ATE_C,ATE_N
k59_211402_1	1165841.SULAR_01763	2.06e-142	405.0	COG1432@1|root,COG1432@2|Bacteria,1MX5C@1224|Proteobacteria,42QHV@68525|delta/epsilon subdivisions,2YNYV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
k59_507727_1	580332.Slit_1666	2.02e-20	98.6	COG2203@1|root,COG4191@1|root,COG5001@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,PAS,PAS_4,PAS_9,SBP_bac_3
k59_730172_1	709032.Sulku_2336	1.03e-122	365.0	COG2194@1|root,COG2194@2|Bacteria,1MWS7@1224|Proteobacteria,42MI1@68525|delta/epsilon subdivisions,2YMPQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Sulfatase	eptA	-	2.7.8.43	ko:K03760	ko01503,map01503	M00722	R11555,R11556,R11557	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DUF1705,Sulfatase
k59_1500641_1	1458275.AZ34_14905	6.56e-22	90.1	COG3663@1|root,COG3663@2|Bacteria,1REPV@1224|Proteobacteria,2VRAT@28216|Betaproteobacteria,4AE11@80864|Comamonadaceae	28216|Betaproteobacteria	L	G T U mismatch-specific DNA glycosylase	mug	-	3.2.2.28	ko:K03649	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
k59_1325224_2	1537917.JU82_06970	8.81e-26	100.0	COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,42RGU@68525|delta/epsilon subdivisions,2YP7I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
k59_572847_1	1485544.JQKP01000012_gene2122	5.67e-114	333.0	COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,2VHC6@28216|Betaproteobacteria,44VC7@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Delta-aminolevulinic acid dehydratase	hemB	GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
k59_447206_1	387093.SUN_1039	7.28e-82	252.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,42M1K@68525|delta/epsilon subdivisions,2YMKR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the peptidase M24B family	pepQ	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
k59_857472_1	1537917.JU82_01685	2.04e-126	362.0	COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,42MZP@68525|delta/epsilon subdivisions,2YMN7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
k59_385952_1	709032.Sulku_0511	8.35e-39	133.0	COG0115@1|root,COG0115@2|Bacteria,1N3ZD@1224|Proteobacteria,42TNN@68525|delta/epsilon subdivisions,2YPU5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EH	Branched-chain amino acid aminotransferase	-	-	4.1.3.38	ko:K02619	ko00790,map00790	-	R05553	RC01843,RC02148	ko00000,ko00001,ko01000	-	-	-	Aminotran_4
k59_1210860_1	1249480.B649_05120	9.49e-26	98.2	COG2010@1|root,COG2010@2|Bacteria,1RH1S@1224|Proteobacteria	1224|Proteobacteria	C	COG2010 Cytochrome c, mono- and diheme variants	exaB	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
k59_1210860_2	1249480.B649_05125	3.97e-30	114.0	COG0715@1|root,COG0715@2|Bacteria,1MWUA@1224|Proteobacteria	1224|Proteobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,SBP_bac_3
k59_1158167_2	1249480.B649_03480	1.89e-30	120.0	COG1629@1|root,COG4771@2|Bacteria,1RKNG@1224|Proteobacteria	1224|Proteobacteria	P	PFAM TonB-dependent Receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_1210861_1	498211.CJA_2005	4.54e-108	323.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,1RN9N@1236|Gammaproteobacteria,1FH5H@10|Cellvibrio	1236|Gammaproteobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051301,GO:0051704,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
k59_1452874_1	1132855.KB913035_gene1523	8.18e-24	99.8	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,2VM67@28216|Betaproteobacteria,2KMG5@206350|Nitrosomonadales	206350|Nitrosomonadales	Q	Multicopper oxidase	-	-	1.16.3.3	ko:K22348	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_2,Cu-oxidase_3
k59_1452874_2	582744.Msip34_0399	3e-44	157.0	COG1538@1|root,COG1538@2|Bacteria,1MWB0@1224|Proteobacteria,2VIIW@28216|Betaproteobacteria,2KM59@206350|Nitrosomonadales	206350|Nitrosomonadales	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_1863908_1	159087.Daro_3422	3.58e-99	291.0	COG5490@1|root,COG5490@2|Bacteria,1R4SV@1224|Proteobacteria,2VQP2@28216|Betaproteobacteria,2KW96@206389|Rhodocyclales	206389|Rhodocyclales	S	Phasin protein	-	-	-	-	-	-	-	-	-	-	-	-	Phasin_2
k59_690873_1	1537917.JU82_11195	8.72e-98	285.0	COG1765@1|root,COG1765@2|Bacteria,1NKRY@1224|Proteobacteria,42UP7@68525|delta/epsilon subdivisions,2YQ0P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	redox protein regulator of disulfide bond formation	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
k59_1796723_1	709032.Sulku_0290	2.27e-51	169.0	COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,42MA4@68525|delta/epsilon subdivisions,2YM9Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901576	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_1796723_2	709032.Sulku_0289	4.17e-78	238.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,42MIF@68525|delta/epsilon subdivisions,2YNW4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
k59_510979_1	395494.Galf_0400	7.69e-117	367.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,2VH3F@28216|Betaproteobacteria,44VF6@713636|Nitrosomonadales	28216|Betaproteobacteria	L	TIGRFAM DNA polymerase III, alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k59_1680570_1	399795.CtesDRAFT_PD1876	2.47e-32	125.0	COG3562@1|root,COG3562@2|Bacteria,1MUZT@1224|Proteobacteria,2VN14@28216|Betaproteobacteria,4ADMQ@80864|Comamonadaceae	28216|Betaproteobacteria	M	Capsule polysaccharide biosynthesis protein	-	-	-	ko:K07265	-	-	-	-	ko00000	-	-	-	Capsule_synth
k59_1452941_1	159087.Daro_3930	8.39e-148	421.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,2VI0M@28216|Betaproteobacteria,2KUD6@206389|Rhodocyclales	206389|Rhodocyclales	M	epimerase dehydratase	-	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase
k59_1622083_1	709032.Sulku_0644	6.3e-75	236.0	COG1143@1|root,COG2768@1|root,COG1143@2|Bacteria,COG2768@2|Bacteria,1N7HT@1224|Proteobacteria	1224|Proteobacteria	C	4fe-4s ferredoxin, iron-sulfur binding	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
k59_1622083_2	1537917.JU82_09710	1.01e-10	60.1	COG3381@1|root,COG3381@2|Bacteria,1N4MX@1224|Proteobacteria,42RVB@68525|delta/epsilon subdivisions,2YP5X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	component of anaerobic	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_del
k59_733436_1	522306.CAP2UW1_1629	4.21e-118	363.0	COG2204@1|root,COG5001@1|root,COG2204@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_4,PAS_9,Response_reg
k59_1045193_1	1537917.JU82_08515	4.96e-138	407.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,43BJ8@68525|delta/epsilon subdivisions,2YMMJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	penicillin-binding protein	pbpA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
k59_803555_1	1249480.B649_08640	4.36e-30	109.0	COG1331@1|root,COG1331@2|Bacteria,1QZ2A@1224|Proteobacteria,42VGW@68525|delta/epsilon subdivisions,2YQEQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH,Thioredoxin_7
k59_1452965_1	709032.Sulku_2546	2.7e-65	214.0	COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,42P71@68525|delta/epsilon subdivisions,2YNAA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Phospholipid glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5,Acyltransferase
k59_1570771_1	709032.Sulku_1893	4.14e-106	324.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2YMMU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_1325439_1	580332.Slit_0806	3.29e-34	126.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,2VNE4@28216|Betaproteobacteria,44WC3@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Beta-eliminating lyase	nifS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5,Rhodanese
k59_1325439_2	1485544.JQKP01000001_gene987	8.18e-54	176.0	COG0694@1|root,COG0822@1|root,COG0694@2|Bacteria,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,2VJE9@28216|Betaproteobacteria,44W7X@713636|Nitrosomonadales	28216|Betaproteobacteria	CO	NifU-like domain	-	-	-	ko:K13819	-	-	-	-	ko00000	-	-	-	Fer2_BFD,NifU,NifU_N
k59_1045215_1	709032.Sulku_2414	1.57e-149	440.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,42MMR@68525|delta/epsilon subdivisions,2YMF0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	GM	Polysaccharide biosynthesis protein	pglF	-	4.2.1.135	ko:K15912	ko00520,map00520	-	-	-	ko00000,ko00001,ko01000	-	-	-	Polysacc_synt_2
k59_1504113_2	1537917.JU82_09375	5.12e-37	137.0	COG3206@1|root,COG3206@2|Bacteria,1Q68V@1224|Proteobacteria,432MZ@68525|delta/epsilon subdivisions,2YSUM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_981547_2	709032.Sulku_1380	3.5e-83	251.0	COG0600@1|root,COG0600@2|Bacteria,1MU6Q@1224|Proteobacteria,42Q2R@68525|delta/epsilon subdivisions,2YNDK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0600 ABC-type nitrate sulfonate bicarbonate transport system permease component	-	-	-	ko:K15577	ko00910,ko02010,map00910,map02010	M00438	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16.1,3.A.1.16.2	-	-	BPD_transp_1
k59_1796835_1	709032.Sulku_0427	6.05e-108	317.0	COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,42PJB@68525|delta/epsilon subdivisions,2YNGQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k59_33434_1	1163617.SCD_n00430	2.71e-58	189.0	COG0826@1|root,COG0826@2|Bacteria,1MWFW@1224|Proteobacteria,2VISF@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Peptidase U32	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_U32
k59_447448_1	1224746.B932_1734	1.09e-69	221.0	COG4694@1|root,COG4694@2|Bacteria,1QWHA@1224|Proteobacteria,2TXW8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_447448_2	1458427.BAWN01000032_gene1778	1.78e-33	127.0	COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria,2VHBK@28216|Betaproteobacteria,4AC6V@80864|Comamonadaceae	28216|Betaproteobacteria	V	type I restriction-modification system	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
k59_733549_1	709032.Sulku_1871	3.12e-43	145.0	COG3663@1|root,COG3663@2|Bacteria,1REPV@1224|Proteobacteria,42SIJ@68525|delta/epsilon subdivisions,2YPP8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	G T U mismatch-specific DNA glycosylase	mug	-	-	-	-	-	-	-	-	-	-	-	UDG
k59_733549_2	709032.Sulku_1872	1.56e-122	355.0	COG1686@1|root,COG1686@2|Bacteria,1MWZA@1224|Proteobacteria,43AWC@68525|delta/epsilon subdivisions,2YT3V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
k59_1278019_1	159087.Daro_2097	1.37e-49	166.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,2VMHD@28216|Betaproteobacteria,2M04C@206389|Rhodocyclales	206389|Rhodocyclales	C	4Fe-4S single cluster domain	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
k59_691056_1	709032.Sulku_0033	3.63e-31	112.0	2DQIB@1|root,3371M@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4430)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4430
k59_691056_2	1178482.BJB45_14355	4.14e-14	73.9	COG0614@1|root,COG0614@2|Bacteria,1MWVF@1224|Proteobacteria,1RMV8@1236|Gammaproteobacteria,1XJ2T@135619|Oceanospirillales	135619|Oceanospirillales	P	COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
k59_386122_1	1537917.JU82_11000	1.01e-209	585.0	COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,42N4P@68525|delta/epsilon subdivisions,2YMDF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
k59_386122_2	1249480.B649_01250	2.28e-114	336.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,42N9Q@68525|delta/epsilon subdivisions,2YMUH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	iIT341.HP0921	Gp_dh_C,Gp_dh_N
k59_270780_1	709032.Sulku_0490	1.1e-18	82.0	COG1432@1|root,COG1432@2|Bacteria,1MX5C@1224|Proteobacteria,42QHV@68525|delta/epsilon subdivisions,2YNYV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
k59_270780_2	1249480.B649_02460	4.45e-49	164.0	COG0327@1|root,COG0327@2|Bacteria,1MVUN@1224|Proteobacteria,42MHJ@68525|delta/epsilon subdivisions,2YMM1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	dinuclear metal center protein, YbgI	-	-	3.5.4.16	ko:K22391	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	NIF3
k59_386147_1	317025.Tcr_1905	1.01e-171	495.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,1RMU8@1236|Gammaproteobacteria,45ZRR@72273|Thiotrichales	72273|Thiotrichales	G	Phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	5.4.2.2,5.4.2.8	ko:K01840,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_90950_1	387093.SUN_0637	4.99e-90	280.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,42ME5@68525|delta/epsilon subdivisions,2YMKK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
k59_1325621_1	1537917.JU82_02720	0.000126	42.0	COG1544@1|root,COG1544@2|Bacteria,1QNAY@1224|Proteobacteria,430WG@68525|delta/epsilon subdivisions,2YS0N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Sigma 54 modulation protein / S30EA ribosomal protein	-	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
k59_1325621_2	709032.Sulku_2153	8.24e-84	249.0	COG3118@1|root,COG3118@2|Bacteria,1RHUA@1224|Proteobacteria,42S1N@68525|delta/epsilon subdivisions,2YPJI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Thioredoxin	-	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
k59_1325621_3	709032.Sulku_2154	1.31e-20	84.7	COG1981@1|root,COG1981@2|Bacteria,1RHGS@1224|Proteobacteria,42ST2@68525|delta/epsilon subdivisions,2YPG7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	membrane	-	-	-	ko:K08973	-	-	-	-	ko00000	-	-	-	UPF0093
k59_511172_1	1167006.UWK_01948	1.05e-96	297.0	COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,42KZP@68525|delta/epsilon subdivisions,2WKSV@28221|Deltaproteobacteria,2MHUQ@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Na H antiporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,PAS
k59_1570960_1	358220.C380_20860	2.25e-67	211.0	COG1360@1|root,COG1360@2|Bacteria,1MW1Y@1224|Proteobacteria,2VHMJ@28216|Betaproteobacteria,4AAE3@80864|Comamonadaceae	28216|Betaproteobacteria	N	PFAM OmpA MotB domain protein	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
k59_1570960_2	1268622.AVS7_03666	5.42e-19	80.1	COG0745@1|root,COG0745@2|Bacteria,1RDNP@1224|Proteobacteria,2VR8X@28216|Betaproteobacteria,4ADYF@80864|Comamonadaceae	28216|Betaproteobacteria	T	response regulator, receiver	cheY	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
k59_1864138_1	1249480.B649_03560	3.38e-130	372.0	COG0745@1|root,COG0745@2|Bacteria,1Q5DC@1224|Proteobacteria,42R42@68525|delta/epsilon subdivisions,2YNXG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_90978_1	1041159.AZUW01000017_gene2141	4.92e-05	47.8	2C8PG@1|root,32RMK@2|Bacteria,1N0UQ@1224|Proteobacteria,2U011@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_857704_1	1286106.MPL1_10432	1.21e-46	174.0	COG0715@1|root,COG0834@1|root,COG5001@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,45ZS0@72273|Thiotrichales	72273|Thiotrichales	T	Diguanylate cyclase phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,NMT1,PAS_9,SBP_bac_3
k59_511211_1	90813.JQMT01000001_gene950	1.04e-33	123.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,1RMHZ@1236|Gammaproteobacteria,460E3@72273|Thiotrichales	72273|Thiotrichales	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
k59_511211_2	1411123.JQNH01000001_gene1385	8.77e-06	50.1	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,2TQXZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
k59_214695_1	1249480.B649_09290	1.38e-81	253.0	2CHQX@1|root,33W06@2|Bacteria,1NWMC@1224|Proteobacteria,42V4N@68525|delta/epsilon subdivisions	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_628590_1	1165841.SULAR_06468	7.38e-161	460.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,42MNB@68525|delta/epsilon subdivisions,2YMKW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
k59_1740271_1	929558.SMGD1_1412	1.11e-82	261.0	COG2010@1|root,COG3391@1|root,COG2010@2|Bacteria,COG3391@2|Bacteria,1N3PN@1224|Proteobacteria,42Q19@68525|delta/epsilon subdivisions,2YNSV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	nitrite reductase	-	-	1.7.2.1,1.7.99.1	ko:K15864	ko00910,ko01120,map00910,map01120	M00529	R00143,R00783,R00785	RC00086,RC02797	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_D1,Cytochrome_CBB3
k59_324294_1	1304883.KI912532_gene2316	4.2e-58	190.0	COG2354@1|root,COG2354@2|Bacteria,1MVYU@1224|Proteobacteria,2VHTU@28216|Betaproteobacteria,2KVKV@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF808)	-	-	-	ko:K09781	-	-	-	-	ko00000	-	-	-	DUF808
k59_324294_2	1304883.KI912532_gene2317	3.56e-26	104.0	COG3064@1|root,COG3064@2|Bacteria,1R56Q@1224|Proteobacteria,2VHQR@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1412040_2	583345.Mmol_0582	3.38e-62	210.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,2VH2J@28216|Betaproteobacteria,2KKE0@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
k59_765788_1	709032.Sulku_1185	3.32e-173	507.0	COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,42M43@68525|delta/epsilon subdivisions,2YM8G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the aconitase IPM isomerase family	acnB	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0045333,GO:0046395,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072329,GO:0072350,GO:0097159,GO:1901363,GO:1901575	4.2.1.3,4.2.1.99	ko:K01682	ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173	R01324,R01325,R01900,R04425	RC00497,RC00498,RC00618,RC01153	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_2_N,Aconitase_B_N
k59_532304_1	159087.Daro_3035	3.41e-44	144.0	COG0268@1|root,COG0268@2|Bacteria,1MZ94@1224|Proteobacteria,2VTYY@28216|Betaproteobacteria,2KWZ9@206389|Rhodocyclales	206389|Rhodocyclales	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
k59_590247_1	1537917.JU82_07735	1.06e-182	529.0	COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,42NB2@68525|delta/epsilon subdivisions,2YMVN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
k59_765792_1	159087.Daro_1177	1.23e-87	270.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,2VI8Z@28216|Betaproteobacteria,2KW53@206389|Rhodocyclales	206389|Rhodocyclales	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
k59_473164_1	1249480.B649_00245	6.83e-61	205.0	COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,42NGP@68525|delta/epsilon subdivisions,2YN81@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Flagellar hook protein flgE	flgE	GO:0005575,GO:0005623,GO:0009288,GO:0009425,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flagellin_IN,Flg_bb_rod,Flg_bbr_C
k59_1530189_1	159087.Daro_0958	7.59e-39	134.0	COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,2VJ4G@28216|Betaproteobacteria,2KW5Z@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
k59_1530189_2	159087.Daro_0959	5.85e-56	175.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,2VSDV@28216|Betaproteobacteria,2KWQG@206389|Rhodocyclales	206389|Rhodocyclales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
k59_1530189_3	159087.Daro_0960	1.97e-116	352.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,2VJ2J@28216|Betaproteobacteria,2KUJW@206389|Rhodocyclales	206389|Rhodocyclales	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
k59_1353126_1	1537917.JU82_04360	1.04e-101	303.0	COG1565@1|root,COG1565@2|Bacteria,1QNDB@1224|Proteobacteria,42MQ8@68525|delta/epsilon subdivisions,2YNBU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
k59_355151_1	563040.Saut_1435	5.87e-25	100.0	COG1472@1|root,COG1472@2|Bacteria,1QUPT@1224|Proteobacteria,42VS9@68525|delta/epsilon subdivisions,2YQD2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Cytochrome c family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365
k59_355151_2	1249480.B649_04185	5.94e-89	262.0	2DQ0J@1|root,3348C@2|Bacteria,1NBQ2@1224|Proteobacteria,42UFN@68525|delta/epsilon subdivisions,2YPUT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Chemoreceptor zinc-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CZB
k59_1412065_1	1249480.B649_07695	6.89e-71	214.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,42SEH@68525|delta/epsilon subdivisions,2YPE2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	FG	Hit family	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
k59_653245_2	1249480.B649_06590	4.1e-84	258.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MSP@68525|delta/epsilon subdivisions,2YNBC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.14	ko:K02594	ko00620,map00620	-	R00271	RC00004,RC00067,RC02754	ko00000,ko00001,ko01000	-	-	-	HMGL-like
k59_1062295_1	387093.SUN_2049	2.31e-112	331.0	COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,42NRV@68525|delta/epsilon subdivisions,2YMK2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
k59_1649819_1	159087.Daro_1000	2.16e-97	301.0	COG3284@1|root,COG3284@2|Bacteria,1NRG5@1224|Proteobacteria,2VICI@28216|Betaproteobacteria,2KV0U@206389|Rhodocyclales	206389|Rhodocyclales	K	Transcriptional activator of acetoin glycerol metabolism	-	-	-	ko:K21405	-	-	-	-	ko00000,ko03000	-	-	-	GAF,HTH_8,Sigma54_activat
k59_416955_1	1123393.KB891316_gene2051	3.48e-181	517.0	COG0318@1|root,COG0318@2|Bacteria,1MXPB@1224|Proteobacteria,2VJ3A@28216|Betaproteobacteria,1KS7J@119069|Hydrogenophilales	119069|Hydrogenophilales	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
k59_416955_2	159087.Daro_4172	1.43e-68	216.0	COG4648@1|root,COG4648@2|Bacteria,1RII0@1224|Proteobacteria,2VSMC@28216|Betaproteobacteria,2KX2J@206389|Rhodocyclales	206389|Rhodocyclales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_709499_1	159087.Daro_0010	1.46e-61	197.0	COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,2VIZ3@28216|Betaproteobacteria,2KUJJ@206389|Rhodocyclales	206389|Rhodocyclales	H	Belongs to the prokaryotic GSH synthase family	gshB	-	6.3.2.3	ko:K01920	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00497,R10994	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	GSH-S_ATP,GSH-S_N
k59_1533591_1	1537917.JU82_08920	5.92e-91	279.0	COG1808@1|root,COG1808@2|Bacteria,1NMS3@1224|Proteobacteria,42PXT@68525|delta/epsilon subdivisions,2YNR0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Domain of unknown function (DUF389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
k59_593248_1	1249480.B649_10825	6.33e-84	248.0	COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,42R43@68525|delta/epsilon subdivisions,2YP73@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
k59_593248_2	1249480.B649_10830	2.56e-13	65.1	COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,42RE3@68525|delta/epsilon subdivisions,2YP8H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
k59_886700_1	1537917.JU82_07460	1.4e-35	130.0	COG0859@1|root,COG0859@2|Bacteria,1NTHI@1224|Proteobacteria	1224|Proteobacteria	M	lipopolysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
k59_886700_2	1249480.B649_09935	4.09e-19	86.3	COG0438@1|root,COG0438@2|Bacteria,1QFQQ@1224|Proteobacteria,42Q8D@68525|delta/epsilon subdivisions,2YMC5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Glycosyl transferases group 1	pglH1	-	2.4.1.292	ko:K17249	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
k59_653275_1	1537917.JU82_09915	1.69e-60	194.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,42N10@68525|delta/epsilon subdivisions,2YMIF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	LU	DNA processing protein	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
k59_653275_2	709032.Sulku_0595	7.19e-58	180.0	COG2010@1|root,COG2010@2|Bacteria,1NJ3U@1224|Proteobacteria,42W80@68525|delta/epsilon subdivisions,2YQGQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	cytochrome C oxidoreductase subunit B	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_593257_1	1249480.B649_07380	3.31e-59	200.0	COG5001@1|root,COG5001@2|Bacteria,1QV5H@1224|Proteobacteria,42PV8@68525|delta/epsilon subdivisions,2YMZX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,LapD_MoxY_N
k59_1004934_1	929558.SMGD1_2619	3.84e-57	197.0	COG2206@1|root,COG3437@1|root,COG2206@2|Bacteria,COG3437@2|Bacteria,1QUN9@1224|Proteobacteria	1224|Proteobacteria	T	Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	-	-	-	-	-	-	-	-	-	PAS,PAS_9,Response_reg
k59_653297_2	159087.Daro_3954	9.54e-34	132.0	COG2199@1|root,COG2703@1|root,COG5000@1|root,COG2199@2|Bacteria,COG2703@2|Bacteria,COG5000@2|Bacteria,1RGCV@1224|Proteobacteria,2VQEF@28216|Betaproteobacteria	28216|Betaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_4,dCache_1
k59_181334_1	1537917.JU82_09840	1.9e-153	445.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,42MYT@68525|delta/epsilon subdivisions,2YMKP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	phosphate transporter	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
k59_1708538_1	1537917.JU82_01665	9.15e-122	384.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2YMP9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5,RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_1473792_1	1537917.JU82_02770	2.72e-48	159.0	COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,42N9N@68525|delta/epsilon subdivisions,2YN1G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
k59_1473792_2	1537917.JU82_02760	1.77e-161	457.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,42N9Q@68525|delta/epsilon subdivisions,2YMUH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	iIT341.HP1346	Gp_dh_C,Gp_dh_N
k59_593322_1	929558.SMGD1_0414	3.73e-123	367.0	COG1944@1|root,COG1944@2|Bacteria,1MV7K@1224|Proteobacteria,42M8K@68525|delta/epsilon subdivisions,2YMZN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	YcaO cyclodehydratase, ATP-ad Mg2+-binding	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	YcaO
k59_1473816_1	550540.Fbal_1991	2.34e-99	311.0	COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,1RPG4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
k59_1355983_1	1537917.JU82_02320	9.71e-59	203.0	COG1287@1|root,COG1287@2|Bacteria,1R8YG@1224|Proteobacteria,43BIB@68525|delta/epsilon subdivisions,2YT8Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Oligosaccharide transferase	-	-	2.4.99.18	ko:K07151	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	STT3
k59_476408_1	557598.LHK_02813	3.47e-40	141.0	COG0250@1|root,COG0250@2|Bacteria,1N01W@1224|Proteobacteria,2VS8U@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components	rfaH	-	-	ko:K05785	-	-	-	-	ko00000,ko03000	-	-	-	NusG
k59_1297371_1	709032.Sulku_0835	4.41e-100	315.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2YNQF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0474 Cation transport ATPase	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3,Na_H_Exchanger
k59_1708613_1	709032.Sulku_1848	1.08e-56	186.0	COG0754@1|root,COG0754@2|Bacteria,1MW6V@1224|Proteobacteria,42N3V@68525|delta/epsilon subdivisions,2YMBJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Glutathionylspermidine synthase	gss	-	-	-	-	-	-	-	-	-	-	-	GSP_synth
k59_1122320_1	159087.Daro_0096	1.83e-116	342.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VHT0@28216|Betaproteobacteria,2KVJQ@206389|Rhodocyclales	206389|Rhodocyclales	C	COG1960 Acyl-CoA dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_417083_2	649638.Trad_1799	7.38e-25	104.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1WI6E@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
k59_1767360_1	159087.Daro_4133	3.3e-74	244.0	COG1570@1|root,COG1570@2|Bacteria,1QWH2@1224|Proteobacteria,2WGZR@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Protein of unknown function (DUF1631)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1631
k59_1062500_1	159087.Daro_0713	2.85e-62	204.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,2VIWB@28216|Betaproteobacteria,2KVB2@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the heme-copper respiratory oxidase family	-	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
k59_1122365_1	1000565.METUNv1_02453	4.46e-45	152.0	COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria,2VJ1K@28216|Betaproteobacteria,2KUV6@206389|Rhodocyclales	206389|Rhodocyclales	T	(FHA) domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
k59_1122365_2	159087.Daro_3360	3.11e-50	167.0	COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,2VM6F@28216|Betaproteobacteria,2KUQG@206389|Rhodocyclales	206389|Rhodocyclales	T	Serine/threonine phosphatases, family 2C, catalytic domain	pppL	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
k59_476475_1	105425.BBPL01000053_gene5680	1.4e-42	151.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,2I1PB@201174|Actinobacteria,2NMZI@228398|Streptacidiphilus	201174|Actinobacteria	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_417124_1	1249480.B649_04975	1.35e-54	175.0	COG1286@1|root,COG1286@2|Bacteria,1NIBK@1224|Proteobacteria,42U0P@68525|delta/epsilon subdivisions,2YPS8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Colicin V production protein	cvpA	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
k59_417124_2	1249480.B649_04980	8.55e-106	315.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,43DAE@68525|delta/epsilon subdivisions,2YTHG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG2199 FOG GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_1650005_1	159087.Daro_1399	4.04e-56	194.0	COG4585@1|root,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,2WEET@28216|Betaproteobacteria,2KVP7@206389|Rhodocyclales	206389|Rhodocyclales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS,dCache_1
k59_709647_2	709032.Sulku_2374	4.98e-44	144.0	COG2841@1|root,COG2841@2|Bacteria,1NGDM@1224|Proteobacteria,42V3Q@68525|delta/epsilon subdivisions,2YQ8Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF465)	-	-	-	ko:K09794	-	-	-	-	ko00000	-	-	-	DUF465
k59_709647_3	1537917.JU82_02430	6.45e-20	84.0	COG2203@1|root,COG2203@2|Bacteria,1NT6X@1224|Proteobacteria,42XRB@68525|delta/epsilon subdivisions,2YRTW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF
k59_7944_1	1434325.AZQN01000001_gene502	7.41e-26	120.0	COG0745@1|root,COG0784@1|root,COG4251@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG4251@2|Bacteria,4NFBM@976|Bacteroidetes,47JRF@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
k59_1062521_1	159087.Daro_3125	1.1e-42	151.0	COG0840@1|root,COG0840@2|Bacteria,1RBQH@1224|Proteobacteria,2VNG3@28216|Betaproteobacteria,2KVTI@206389|Rhodocyclales	1224|Proteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
k59_1062521_2	640081.Dsui_2937	4.21e-58	191.0	COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,2VIDR@28216|Betaproteobacteria,2KURP@206389|Rhodocyclales	206389|Rhodocyclales	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
k59_476503_2	745718.JADT01000003_gene2251	1.03e-09	66.2	COG2356@1|root,COG3227@1|root,COG3291@1|root,COG2356@2|Bacteria,COG3227@2|Bacteria,COG3291@2|Bacteria,4NF8H@976|Bacteroidetes,1IJ61@117743|Flavobacteriia	976|Bacteroidetes	E	Thermolysin metallopeptidase, catalytic domain	-	-	3.4.24.28	ko:K01400	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF5011,FTP,Inhibitor_I69,MAM,Peptidase_C10,Peptidase_M14,Peptidase_M4,Peptidase_M43,Peptidase_M4_C,Reprolysin_4,fn3
k59_358072_1	1537917.JU82_11275	2.79e-95	290.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,42MFC@68525|delta/epsilon subdivisions,2YMN5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iIT341.HP0976	AAA_26,Aminotran_3
k59_64464_1	159087.Daro_0735	1.25e-64	205.0	COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1N81M@1224|Proteobacteria,2VI4E@28216|Betaproteobacteria,2KV3U@206389|Rhodocyclales	206389|Rhodocyclales	T	Chemotaxis signal transduction protein	-	-	-	ko:K03415	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CheW,Response_reg
k59_64464_2	640081.Dsui_1717	2.55e-48	163.0	COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1N81M@1224|Proteobacteria,2VI4E@28216|Betaproteobacteria,2KVCH@206389|Rhodocyclales	206389|Rhodocyclales	T	Chemotaxis signal transduction protein	-	-	-	ko:K03415	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CheW,Response_reg
k59_1180601_1	62928.azo3017	3.35e-10	60.1	COG3203@1|root,COG3203@2|Bacteria,1MWUN@1224|Proteobacteria,2VN8D@28216|Betaproteobacteria,2KUJ1@206389|Rhodocyclales	206389|Rhodocyclales	M	Outer membrane protein (Porin)	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
k59_1708693_1	709032.Sulku_2090	2.83e-144	415.0	COG0731@1|root,COG0731@2|Bacteria,1QG36@1224|Proteobacteria,42M82@68525|delta/epsilon subdivisions,2YN42@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
k59_417159_1	709032.Sulku_0608	1.08e-20	89.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,42SCV@68525|delta/epsilon subdivisions,2YPRK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar motor	motB	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
k59_417159_2	1537917.JU82_09840	1.4e-126	374.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,42MYT@68525|delta/epsilon subdivisions,2YMKP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	phosphate transporter	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
k59_181493_2	87626.PTD2_09264	2.75e-06	49.7	COG2199@1|root,COG3292@1|root,COG3292@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RQCR@1236|Gammaproteobacteria,2PZG0@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	T	periplasmic ligand-binding sensor domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Reg_prop,Y_Y_Y
k59_1180614_1	159087.Daro_3208	3.76e-24	98.6	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,2VHPG@28216|Betaproteobacteria,2KU8U@206389|Rhodocyclales	206389|Rhodocyclales	F	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
k59_1180614_2	159087.Daro_3207	1.88e-34	117.0	COG2835@1|root,COG2835@2|Bacteria,1N6Y2@1224|Proteobacteria,2VW58@28216|Betaproteobacteria,2KXCI@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the UPF0434 family	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
k59_1180614_3	1304883.KI912532_gene3184	4.76e-51	167.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,2VINM@28216|Betaproteobacteria,2KU7X@206389|Rhodocyclales	206389|Rhodocyclales	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
k59_64479_1	1537917.JU82_01885	1.13e-140	403.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,42NBV@68525|delta/epsilon subdivisions,2YM8U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
k59_1533832_1	1172190.M947_00885	3.57e-10	59.3	2AJ5D@1|root,319PZ@2|Bacteria,1Q3HS@1224|Proteobacteria,42XCD@68525|delta/epsilon subdivisions,2YQQ3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Chemotaxis phosphatase CheX	-	-	-	-	-	-	-	-	-	-	-	-	CheX
k59_1533832_2	1537917.JU82_07810	1.19e-57	181.0	COG1886@1|root,COG1886@2|Bacteria,1NNYT@1224|Proteobacteria,42U38@68525|delta/epsilon subdivisions,2YPTT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar motor switch protein	fliN	-	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FliMN_C
k59_536052_1	709032.Sulku_2254	5.19e-125	363.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,42MKD@68525|delta/epsilon subdivisions,2YMRD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k59_1827503_2	387093.SUN_1179	9.6e-67	214.0	COG4948@1|root,COG4948@2|Bacteria,1MU8R@1224|Proteobacteria,43BF8@68525|delta/epsilon subdivisions,2YT83@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
k59_124177_1	159087.Daro_3426	2.81e-109	347.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,2VI3R@28216|Betaproteobacteria,2KUB1@206389|Rhodocyclales	206389|Rhodocyclales	L	Helicase associated domain (HA2)  Add an annotation	hrpA	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
k59_828806_1	1537917.JU82_06845	4.65e-72	219.0	COG0622@1|root,COG0622@2|Bacteria,1NPH4@1224|Proteobacteria,42TB8@68525|delta/epsilon subdivisions,2YPHV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Phosphoesterase	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
k59_828806_2	1537917.JU82_06850	1.33e-179	502.0	COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,42NGR@68525|delta/epsilon subdivisions,2YMH4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
k59_1297486_1	395494.Galf_1307	3.75e-86	280.0	COG0642@1|root,COG0784@1|root,COG3850@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG3850@2|Bacteria,1NRP8@1224|Proteobacteria,2VJVN@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE5,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
k59_768554_1	396595.TK90_1447	1.09e-07	58.5	COG1345@1|root,COG1345@2|Bacteria,1MUVP@1224|Proteobacteria,1RS2S@1236|Gammaproteobacteria,1WYTJ@135613|Chromatiales	135613|Chromatiales	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	-	-	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_IN,FliD_C,FliD_N
k59_886936_1	709032.Sulku_1866	4.02e-61	196.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,42NBY@68525|delta/epsilon subdivisions,2YMSY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Co-chaperone-curved DNA binding protein A	cbpA	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
k59_64492_1	1165841.SULAR_04768	4.64e-41	147.0	COG0472@1|root,COG0472@2|Bacteria,1MWYW@1224|Proteobacteria,42QFA@68525|delta/epsilon subdivisions,2YTPJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
k59_64492_2	709032.Sulku_0132	4.8e-50	169.0	COG4773@1|root,COG4773@2|Bacteria,1QZMX@1224|Proteobacteria,42SA0@68525|delta/epsilon subdivisions,2YPCD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_886938_1	709032.Sulku_1269	4.35e-63	206.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2YNK4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
k59_886938_2	1249480.B649_05385	1.51e-41	149.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2YR9K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	-	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
k59_1297494_1	640081.Dsui_2770	3.42e-141	422.0	COG4953@1|root,COG4953@2|Bacteria,1MUA9@1224|Proteobacteria,2VMGW@28216|Betaproteobacteria,2KVV8@206389|Rhodocyclales	206389|Rhodocyclales	M	Transglycosylase	-	-	2.4.1.129	ko:K05367	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	BiPBP_C,Transgly,Transpeptidase
k59_1827539_1	314256.OG2516_18905	5.98e-33	129.0	COG0500@1|root,COG4122@1|root,COG0500@2|Bacteria,COG4122@2|Bacteria,1PF46@1224|Proteobacteria,2VB4G@28211|Alphaproteobacteria,2PFSR@252301|Oceanicola	28211|Alphaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
k59_536092_1	1279038.KB907356_gene2004	8.24e-55	199.0	COG0642@1|root,COG4251@1|root,COG0642@2|Bacteria,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,2TZS6@28211|Alphaproteobacteria,2JZ5S@204441|Rhodospirillales	204441|Rhodospirillales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
k59_241155_1	709032.Sulku_0065	7.83e-51	178.0	COG4581@1|root,COG4581@2|Bacteria,1MVD6@1224|Proteobacteria,42PR3@68525|delta/epsilon subdivisions,2YN2Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Mitochondrial degradasome RNA helicase subunit C terminal	-	-	3.6.4.13	ko:K17675	-	-	-	-	ko00000,ko01000,ko03029	-	-	-	Helicase_C,SUV3_C
k59_241155_2	1249480.B649_00210	2.73e-43	156.0	COG4581@1|root,COG4581@2|Bacteria,1MVD6@1224|Proteobacteria,42PR3@68525|delta/epsilon subdivisions,2YN2Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Mitochondrial degradasome RNA helicase subunit C terminal	-	-	3.6.4.13	ko:K17675	-	-	-	-	ko00000,ko01000,ko03029	-	-	-	Helicase_C,SUV3_C
k59_124224_1	1282876.BAOK01000001_gene3656	1.51e-20	96.7	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,4BSU4@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	Q	Cadherin repeats.	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
k59_619763_1	929558.SMGD1_1726	1.08e-63	216.0	COG0457@1|root,COG0457@2|Bacteria,1MWHE@1224|Proteobacteria,42S1C@68525|delta/epsilon subdivisions,2YNIM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF560,TPR_16
k59_1149389_1	709032.Sulku_2165	1.2e-313	862.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2YMN1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DEAD box helicase family	deaD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
k59_1149389_2	1537917.JU82_02665	5.52e-66	202.0	COG0537@1|root,COG0537@2|Bacteria,1MZVD@1224|Proteobacteria,42TMC@68525|delta/epsilon subdivisions,2YPSJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	FG	(HIT) family	-	-	-	-	-	-	-	-	-	-	-	-	HIT
k59_263588_1	948106.AWZT01000005_gene4429	2.33e-07	50.8	COG1949@1|root,COG1949@2|Bacteria,1R9WX@1224|Proteobacteria,2VIA2@28216|Betaproteobacteria,1K394@119060|Burkholderiaceae	28216|Betaproteobacteria	L	3'-to-5' exoribonuclease specific for small oligoribonucleotides	orn	-	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
k59_853891_1	1094980.Mpsy_1301	4.42e-49	174.0	COG1796@1|root,arCOG00305@2157|Archaea,2XT14@28890|Euryarchaeota,2N90T@224756|Methanomicrobia	224756|Methanomicrobia	L	Helix-hairpin-helix domain	polX	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5,HHH_8,PHP
k59_568501_1	1249480.B649_05010	3.59e-80	244.0	COG4649@1|root,COG4649@2|Bacteria,1Q2HI@1224|Proteobacteria,42VQJ@68525|delta/epsilon subdivisions,2YQ7B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TPR_21
k59_568501_2	1249480.B649_05015	1.28e-17	81.3	2AGMT@1|root,316V3@2|Bacteria,1PY20@1224|Proteobacteria,42NND@68525|delta/epsilon subdivisions,2YMQB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	pgbB	-	-	-	-	-	-	-	-	-	-	-	PGBA_C,PQQ_2
k59_1617002_1	929558.SMGD1_1977	5.81e-65	219.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1RGCV@1224|Proteobacteria,43CEF@68525|delta/epsilon subdivisions,2YTC1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_153533_1	1355374.JARU01000003_gene1157	5.47e-39	150.0	COG5001@1|root,COG5001@2|Bacteria,1R4H0@1224|Proteobacteria,42Q74@68525|delta/epsilon subdivisions,2YMQI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,EAL,GGDEF,PAS_3,PAS_9
k59_622737_1	583345.Mmol_2147	2.4e-107	330.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,2VHY4@28216|Betaproteobacteria,2KKNT@206350|Nitrosomonadales	206350|Nitrosomonadales	U	type II and III secretion system protein	-	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
k59_685286_1	159087.Daro_0154	1.12e-51	177.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2VHAN@28216|Betaproteobacteria,2KUTR@206389|Rhodocyclales	206389|Rhodocyclales	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	msbA	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
k59_685286_2	159087.Daro_0153	7.52e-75	235.0	COG0438@1|root,COG0438@2|Bacteria,1NE3V@1224|Proteobacteria,2VJET@28216|Betaproteobacteria,2KUQ5@206389|Rhodocyclales	206389|Rhodocyclales	M	Glycosyl transferases group 1	-	-	-	ko:K02844	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
k59_1565399_1	1537917.JU82_07905	3.91e-32	114.0	COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,42UF8@68525|delta/epsilon subdivisions,2YPGM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	chain release factor	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
k59_1565399_2	1537917.JU82_00735	2.6e-63	202.0	28M05@1|root,32SJ0@2|Bacteria,1N115@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1272425_1	709032.Sulku_0366	1.12e-86	262.0	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,42NC2@68525|delta/epsilon subdivisions,2YMTQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
k59_1272425_2	1537917.JU82_04015	1.36e-22	94.0	COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,42MQQ@68525|delta/epsilon subdivisions,2YNAG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	dna polymerase iii	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_381411_1	159087.Daro_0598	6.37e-117	342.0	COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,2VH1J@28216|Betaproteobacteria,2KURQ@206389|Rhodocyclales	206389|Rhodocyclales	C	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k59_209254_2	396588.Tgr7_0508	1.2e-34	123.0	COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,1S3QR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Peptidyl-prolyl cis-trans	slyD	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006464,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010467,GO:0016151,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0022417,GO:0031647,GO:0035821,GO:0036211,GO:0042026,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043963,GO:0044003,GO:0044068,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0044501,GO:0046872,GO:0046914,GO:0050821,GO:0050896,GO:0050897,GO:0051082,GO:0051604,GO:0051701,GO:0051704,GO:0051817,GO:0052027,GO:0052250,GO:0065007,GO:0065008,GO:0071704,GO:0140096,GO:1901564	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
k59_1565410_1	420662.Mpe_A0110	1.27e-46	166.0	COG0038@1|root,COG0038@2|Bacteria,1MV4K@1224|Proteobacteria,2VHFE@28216|Betaproteobacteria,1KKGE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Voltage gated chloride channel	clcA	-	-	-	-	-	-	-	-	-	-	-	Voltage_CLC
k59_1858970_1	631362.Thi970DRAFT_03542	1.5e-97	295.0	COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,1T1GA@1236|Gammaproteobacteria,1WWQR@135613|Chromatiales	135613|Chromatiales	E	PFAM Cys Met metabolism	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
k59_1090501_1	709032.Sulku_0933	2.44e-120	353.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42N0H@68525|delta/epsilon subdivisions,2YMMP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the peptidase M16 family	pqqL	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_1498985_1	709032.Sulku_0375	4.92e-178	510.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,42M3D@68525|delta/epsilon subdivisions,2YMAA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
k59_853925_1	279714.FuraDRAFT_0720	5.13e-07	57.0	COG0739@1|root,COG3061@1|root,COG0739@2|Bacteria,COG3061@2|Bacteria,1MVTF@1224|Proteobacteria,2VHBS@28216|Betaproteobacteria,2KQNX@206351|Neisseriales	206351|Neisseriales	M	Peptidase, M23 family	-	-	-	-	-	-	-	-	-	-	-	-	OapA,Peptidase_M23
k59_1792522_1	1463825.JNXC01000003_gene4022	6.54e-07	52.4	COG0745@1|root,COG0745@2|Bacteria,2GKJK@201174|Actinobacteria,4DYT4@85010|Pseudonocardiales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_728755_1	1249480.B649_11340	1.26e-14	78.6	COG2885@1|root,COG2885@2|Bacteria,1QW22@1224|Proteobacteria,42NCQ@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	OmpA MotB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,OmpA
k59_1039911_1	1535422.ND16A_2625	2.86e-95	294.0	COG2010@1|root,COG3391@1|root,COG2010@2|Bacteria,COG3391@2|Bacteria,1PYK3@1224|Proteobacteria,1RR3N@1236|Gammaproteobacteria,2Q81G@267889|Colwelliaceae	1236|Gammaproteobacteria	C	Cytochrome D1 heme domain	nirN	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1,Cytochrome_CBB3
k59_1792527_1	743974.MBO_00645	1.04e-71	232.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,1RMP2@1236|Gammaproteobacteria,3NJMA@468|Moraxellaceae	1236|Gammaproteobacteria	EG	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
k59_1272468_1	470.IX87_14905	9.26e-28	113.0	COG0472@1|root,COG0472@2|Bacteria,1MWYW@1224|Proteobacteria,1RNAP@1236|Gammaproteobacteria,3NM0E@468|Moraxellaceae	1236|Gammaproteobacteria	M	Glycosyl transferase family 4	wbpL	-	-	ko:K13007	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
k59_1319970_1	1249480.B649_08745	9.23e-68	215.0	COG0457@1|root,COG0457@2|Bacteria,1Q60C@1224|Proteobacteria,42X29@68525|delta/epsilon subdivisions,2YQQA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Anaphase-promoting complex, cyclosome, subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC3
k59_1272505_1	709032.Sulku_0933	8.83e-216	602.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42N0H@68525|delta/epsilon subdivisions,2YMMP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the peptidase M16 family	pqqL	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_1272510_1	709032.Sulku_1895	1.81e-73	221.0	COG2199@1|root,COG3706@2|Bacteria,1N0N3@1224|Proteobacteria,43E7J@68525|delta/epsilon subdivisions,2YTC4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Chemotaxis protein cheY	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
k59_1272510_2	1249480.B649_09070	1.13e-56	183.0	COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,42NSS@68525|delta/epsilon subdivisions,2YNZK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
k59_685380_1	1537917.JU82_11795	1.22e-187	523.0	COG0583@1|root,COG0583@2|Bacteria,1R8CE@1224|Proteobacteria,42PKW@68525|delta/epsilon subdivisions,2YNJK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_797984_1	522306.CAP2UW1_2295	3.1e-52	179.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VJGE@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	hoxJ	-	2.7.13.3	ko:K19661	ko02020,map02020	M00772	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9,cNMP_binding
k59_1205885_1	1122211.JMLW01000001_gene2332	6.98e-34	132.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,1RMIX@1236|Gammaproteobacteria,1XH5P@135619|Oceanospirillales	135619|Oceanospirillales	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
k59_1859075_1	1249480.B649_06425	6.89e-92	293.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2YRKW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0474 Cation transport ATPase	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
k59_1090605_1	1537917.JU82_04145	5.63e-37	127.0	2BTXE@1|root,32P5J@2|Bacteria,1Q8QR@1224|Proteobacteria,431VI@68525|delta/epsilon subdivisions,2YS9R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1090605_2	709032.Sulku_2500	1.84e-73	223.0	COG0352@1|root,COG0352@2|Bacteria,1P3Q4@1224|Proteobacteria,42SIF@68525|delta/epsilon subdivisions,2YPJ7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	thiamine-phosphate diphosphorylase activity	-	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	-
k59_1499079_1	929506.CbC4_0113	2.01e-60	204.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,36E1W@31979|Clostridiaceae	186801|Clostridia	T	Diguanylate cyclase	nifL	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HisKA_7TM,PAS_9
k59_86834_1	1509405.GV67_00200	2.27e-39	145.0	COG2828@1|root,COG2828@2|Bacteria,1MXVV@1224|Proteobacteria,2TQMC@28211|Alphaproteobacteria,4B9H9@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	PrpF protein	-	-	5.3.2.8	ko:K16514	ko00362,ko01120,map00362,map01120	-	R07839	RC02426	ko00000,ko00001,ko01000	-	-	-	PrpF
k59_86834_2	338969.Rfer_3481	2.47e-15	75.5	COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,2VM8V@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k59_1448227_2	767434.Fraau_2716	7.63e-43	151.0	COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,1RSKV@1236|Gammaproteobacteria,1X40S@135614|Xanthomonadales	135614|Xanthomonadales	GM	NAD(P)H-binding	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	Epimerase,NAD_binding_10
k59_266679_1	1123252.ATZF01000009_gene644	4.27e-108	325.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,4H9U4@91061|Bacilli,27B75@186824|Thermoactinomycetaceae	91061|Bacilli	O	ClpX C4-type zinc finger	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
k59_266679_2	743974.MBO_08631	4.04e-111	323.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,1RNR6@1236|Gammaproteobacteria,3NIST@468|Moraxellaceae	1236|Gammaproteobacteria	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	GO:0000502,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009314,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0010498,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017171,GO:0019538,GO:0019899,GO:0030163,GO:0031597,GO:0032991,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051117,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
k59_1859140_1	709032.Sulku_0003	1.37e-161	473.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,42M7M@68525|delta/epsilon subdivisions,2YMUW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_1617187_1	709032.Sulku_0766	4.47e-54	179.0	COG1729@1|root,COG1729@2|Bacteria,1NG81@1224|Proteobacteria,42R1Z@68525|delta/epsilon subdivisions,2YNY7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	repeat protein	ybgF	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_6
k59_622944_1	345073.VC395_0248	3.12e-25	112.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMV2@1236|Gammaproteobacteria,1XSAN@135623|Vibrionales	135623|Vibrionales	T	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,sCache_2
k59_568753_1	159087.Daro_0567	7.25e-188	533.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,2VIAX@28216|Betaproteobacteria,2KVU3@206389|Rhodocyclales	1224|Proteobacteria	C	COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M)	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k59_1448272_1	1123371.ATXH01000007_gene541	1.01e-49	176.0	COG0119@1|root,COG0119@2|Bacteria,2GHCY@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	HMGL-like,dCache_1
k59_1090709_1	525898.Sdel_1998	4.36e-99	294.0	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,42QX7@68525|delta/epsilon subdivisions,2YRDE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	PFAM IstB domain protein ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
k59_1153079_1	709032.Sulku_1562	3.58e-119	344.0	COG1994@1|root,COG1994@2|Bacteria,1N531@1224|Proteobacteria,43AZN@68525|delta/epsilon subdivisions,2YP0U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
k59_266741_1	1158345.JNLL01000001_gene10	1.2e-79	251.0	arCOG03638@1|root,2Z8W3@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1538)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1538
k59_1272665_1	159087.Daro_1577	7.67e-90	266.0	COG1999@1|root,COG1999@2|Bacteria,1RHJ8@1224|Proteobacteria,2VSDI@28216|Betaproteobacteria,2KYY4@206389|Rhodocyclales	206389|Rhodocyclales	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
k59_1272665_2	159087.Daro_1578	5.7e-49	159.0	COG2847@1|root,COG2847@2|Bacteria,1MZ3M@1224|Proteobacteria,2VTY7@28216|Betaproteobacteria,2KWMU@206389|Rhodocyclales	206389|Rhodocyclales	S	Copper chaperone PCu(A)C	-	-	-	ko:K09796	-	-	-	-	ko00000,ko03110	-	-	-	PCuAC
k59_1383046_1	1249480.B649_01450	6.57e-76	243.0	COG2198@1|root,COG2198@2|Bacteria,1PCKH@1224|Proteobacteria,42W9Z@68525|delta/epsilon subdivisions,2YQ6K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_976015_1	1165841.SULAR_09399	6.57e-148	438.0	COG1262@1|root,COG1352@1|root,COG1262@2|Bacteria,COG1352@2|Bacteria,1MUNC@1224|Proteobacteria,42N4Y@68525|delta/epsilon subdivisions,2YNCE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase,Methyltransf_11,Methyltransf_31
k59_1792735_1	1132855.KB913035_gene1168	1.29e-168	482.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,2VHJ9@28216|Betaproteobacteria,2KKXM@206350|Nitrosomonadales	206350|Nitrosomonadales	S	PFAM peptidase U62 modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
k59_153841_1	159087.Daro_2777	1.47e-29	116.0	COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1NR1S@1224|Proteobacteria,2W0HM@28216|Betaproteobacteria,2KY6D@206389|Rhodocyclales	206389|Rhodocyclales	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.8	ko:K04090	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR,TPP_enzyme_C
k59_153841_2	159087.Daro_2778	1.95e-57	189.0	COG4638@1|root,COG4638@2|Bacteria,1N6MJ@1224|Proteobacteria,2VJ0B@28216|Betaproteobacteria,2KWQ2@206389|Rhodocyclales	206389|Rhodocyclales	C	Hydroxylase large component of 1,2-dioxygenase protein complex, involved in aromatic compounds degradation	-	-	1.14.12.10	ko:K05549	ko00362,ko00364,ko00622,ko01100,ko01120,ko01220,map00362,map00364,map00622,map01100,map01120,map01220	M00551	R05290,R05291,R05428,R05621,R05622,R05665,R08100,R08101,R08108,R08109,R08110	RC00270,RC01378,RC01450,RC01910	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
k59_976047_2	159087.Daro_3792	2.95e-114	335.0	COG2871@1|root,COG2871@2|Bacteria,1QTUV@1224|Proteobacteria,2VIBG@28216|Betaproteobacteria,2KUW1@206389|Rhodocyclales	206389|Rhodocyclales	C	COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases	-	-	-	ko:K16246	ko00361,ko00362,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00623,map01100,map01120,map01220	M00548	R03560,R03608,R10042,R10043	RC00046,RC00490	ko00000,ko00001,ko00002	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
k59_685597_1	159087.Daro_2490	6.86e-85	268.0	COG0715@1|root,COG4191@1|root,COG0715@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VMN8@28216|Betaproteobacteria,2KUPQ@206389|Rhodocyclales	206389|Rhodocyclales	T	Histidine kinase	-	-	2.7.13.3	ko:K13040	ko02020,map02020	M00514	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Phosphonate-bd
k59_266810_1	1537917.JU82_09210	1.42e-130	389.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,42NGS@68525|delta/epsilon subdivisions,2YMZZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Ribonuclease	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB
k59_1448417_1	709032.Sulku_1467	3.3e-77	243.0	COG0642@1|root,COG5000@1|root,COG0642@2|Bacteria,COG5000@2|Bacteria,1N5IQ@1224|Proteobacteria,42N7Z@68525|delta/epsilon subdivisions,2YN64@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
k59_1617328_1	1123514.KB905899_gene1053	1.29e-62	199.0	COG2860@1|root,COG2860@2|Bacteria,1RHQN@1224|Proteobacteria,1S5YY@1236|Gammaproteobacteria,4610T@72273|Thiotrichales	72273|Thiotrichales	S	UPF0126 domain	-	-	-	-	-	-	-	-	-	-	-	-	UPF0126
k59_506277_1	90814.KL370892_gene2336	3.29e-91	300.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,45ZPF@72273|Thiotrichales	72273|Thiotrichales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1153209_1	1249480.B649_00160	2.41e-30	107.0	COG0828@1|root,COG0828@2|Bacteria,1Q61C@1224|Proteobacteria,42VSR@68525|delta/epsilon subdivisions,2YQAH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
k59_1792816_1	709032.Sulku_1825	7.18e-97	283.0	COG4681@1|root,COG4681@2|Bacteria,1RDR9@1224|Proteobacteria,42QRY@68525|delta/epsilon subdivisions,2YRU2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	YaeQ	-	-	-	-	-	-	-	-	-	-	-	-	YaeQ
k59_1448444_1	1165841.SULAR_10264	1.22e-96	291.0	COG0027@1|root,COG0027@2|Bacteria,1N3KA@1224|Proteobacteria,42MYW@68525|delta/epsilon subdivisions,2YN5Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate	purT	-	2.1.2.2	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
k59_1090847_1	709032.Sulku_1480	3.15e-48	172.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,42WJ0@68525|delta/epsilon subdivisions,2YQJR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	PFAM TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_153950_1	929558.SMGD1_1985	4.61e-40	140.0	COG1032@1|root,COG1032@2|Bacteria,1P9J0@1224|Proteobacteria,42MWG@68525|delta/epsilon subdivisions,2YP0Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k59_1620138_1	1003200.AXXA_26150	1.33e-52	179.0	28KSV@1|root,2ZAA5@2|Bacteria,1R8PW@1224|Proteobacteria,2VMYF@28216|Betaproteobacteria,3T32M@506|Alcaligenaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_156924_1	1163617.SCD_n01558	2.42e-05	43.9	COG2345@1|root,COG2345@2|Bacteria,1N9W3@1224|Proteobacteria,2VWG0@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_156924_2	1304883.KI912532_gene325	3.97e-60	201.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,2VH74@28216|Betaproteobacteria,2KVA2@206389|Rhodocyclales	206389|Rhodocyclales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_1156270_1	1249480.B649_02215	1.63e-62	206.0	COG4773@1|root,COG4773@2|Bacteria,1QZ1U@1224|Proteobacteria,42PHE@68525|delta/epsilon subdivisions,2YN5J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Receptor	-	-	-	-	-	-	-	-	-	-	-	-	OprD
k59_1620155_1	159087.Daro_0219	2.92e-97	288.0	COG0640@1|root,COG0640@2|Bacteria,1RBZC@1224|Proteobacteria,2VR13@28216|Betaproteobacteria,2KW3M@206389|Rhodocyclales	206389|Rhodocyclales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1737360_1	580332.Slit_1666	2.09e-44	166.0	COG2203@1|root,COG4191@1|root,COG5001@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,PAS,PAS_4,PAS_9,SBP_bac_3
k59_829995_1	159087.Daro_3371	2.81e-180	508.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VJ9G@28216|Betaproteobacteria,2KV5H@206389|Rhodocyclales	206389|Rhodocyclales	O	Belongs to the peptidase S1C family	-	-	-	ko:K04691,ko:K04772	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
k59_710529_1	1120999.JONM01000002_gene667	1.38e-76	238.0	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,2VIWA@28216|Betaproteobacteria,2KTTP@206351|Neisseriales	206351|Neisseriales	M	Mechanosensitive ion channel	-	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel
k59_125552_1	582744.Msip34_1972	4.66e-44	157.0	COG1463@1|root,COG3008@1|root,COG1463@2|Bacteria,COG3008@2|Bacteria,1MU1T@1224|Proteobacteria,2VJ44@28216|Betaproteobacteria,2KKG1@206350|Nitrosomonadales	206350|Nitrosomonadales	Q	MlaD protein	-	-	-	ko:K06192	-	-	-	-	ko00000	-	-	-	MlaD
k59_125552_2	1500893.JQNB01000001_gene3055	1.14e-21	88.6	COG2995@1|root,COG2995@2|Bacteria,1MWG1@1224|Proteobacteria,1S2AT@1236|Gammaproteobacteria,1XCMC@135614|Xanthomonadales	135614|Xanthomonadales	S	Paraquat-inducible protein A	-	-	-	-	-	-	-	-	-	-	-	-	PqiA
k59_594752_1	159087.Daro_3907	2.04e-65	208.0	COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,2VHHC@28216|Betaproteobacteria,2KUFF@206389|Rhodocyclales	206389|Rhodocyclales	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
k59_1651280_1	1123517.JOMR01000001_gene921	1.22e-64	214.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,1RNMI@1236|Gammaproteobacteria,45ZZ8@72273|Thiotrichales	72273|Thiotrichales	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
k59_654787_1	1249480.B649_07290	7.89e-130	375.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,42M2J@68525|delta/epsilon subdivisions,2YN8F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	frdB	-	1.3.5.1,1.3.5.4	ko:K00240,ko:K00245	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0191	Fer2_3,Fer4_8
k59_125561_1	709032.Sulku_0647	3.08e-104	319.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42S84@68525|delta/epsilon subdivisions,2YPD4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_3
k59_1709865_1	709032.Sulku_2438	5.41e-75	229.0	COG2353@1|root,COG2353@2|Bacteria,1PDM9@1224|Proteobacteria,42TFW@68525|delta/epsilon subdivisions,2YQ0K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
k59_1709865_2	387093.SUN_1075	8.5e-08	54.7	COG2220@1|root,COG2220@2|Bacteria,1MV20@1224|Proteobacteria,42QPP@68525|delta/epsilon subdivisions,2YP9R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
k59_710545_1	317025.Tcr_1547	3.42e-77	234.0	COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,1RMZM@1236|Gammaproteobacteria,460MB@72273|Thiotrichales	72273|Thiotrichales	H	TIGRFAM molybdenum cofactor synthesis	-	-	2.7.7.75	ko:K03831	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
k59_8980_1	159087.Daro_1602	1.04e-24	102.0	COG0515@1|root,COG1639@1|root,COG2203@1|root,COG0515@2|Bacteria,COG1639@2|Bacteria,COG2203@2|Bacteria,1NJC4@1224|Proteobacteria,2VHRZ@28216|Betaproteobacteria,2KUM0@206389|Rhodocyclales	206389|Rhodocyclales	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HDOD,Pkinase
k59_8980_2	159087.Daro_1601	2.28e-67	207.0	2DRAF@1|root,33AYA@2|Bacteria,1NGMJ@1224|Proteobacteria,2VXTM@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3293)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3293
k59_1475338_2	1279017.AQYJ01000029_gene3546	7.96e-15	68.6	2DNYP@1|root,32ZTI@2|Bacteria,1N747@1224|Proteobacteria,1SCCQ@1236|Gammaproteobacteria,46CA9@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
k59_537476_1	944546.ABED_1446	3.32e-76	256.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42PTS@68525|delta/epsilon subdivisions,2YNBM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_1535116_1	1348657.M622_02610	7.67e-98	298.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VI4Q@28216|Betaproteobacteria,2KVHE@206389|Rhodocyclales	206389|Rhodocyclales	O	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
k59_537490_1	1249480.B649_05370	4.01e-16	76.6	COG1449@1|root,COG1449@2|Bacteria,1P2YJ@1224|Proteobacteria,42N8E@68525|delta/epsilon subdivisions,2YNF0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
k59_537490_2	1249480.B649_05365	9.65e-175	511.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42MX5@68525|delta/epsilon subdivisions,2YMSQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)	-	-	2.7.7.13,5.4.2.8	ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II
k59_1768579_2	649747.HMPREF0083_00279	1.83e-13	73.2	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,4HAHU@91061|Bacilli,26Q93@186822|Paenibacillaceae	91061|Bacilli	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	ko:K16123,ko:K16124	ko01054,map01054	-	-	-	ko00000,ko00001,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_1063912_1	159087.Daro_0313	5.53e-142	438.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,2VIF3@28216|Betaproteobacteria,2KUZA@206389|Rhodocyclales	206389|Rhodocyclales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_1063914_1	1537917.JU82_11050	1.06e-129	384.0	COG1166@1|root,COG1166@2|Bacteria,1MU80@1224|Proteobacteria,42M2B@68525|delta/epsilon subdivisions,2YMP0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	arginine decarboxylase	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0422	Orn_Arg_deC_N
k59_1592722_1	269482.Bcep1808_2318	5.51e-16	75.1	COG5319@1|root,COG5319@2|Bacteria,1MZN2@1224|Proteobacteria,2VSCN@28216|Betaproteobacteria,1K73W@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1178)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1178
k59_594828_1	243924.LT42_08875	2.48e-32	126.0	COG0642@1|root,COG0642@2|Bacteria,1MURQ@1224|Proteobacteria,1RP9C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	fleS	-	2.7.13.3	ko:K10942	ko02020,ko05111,map02020,map05111	M00515	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_8
k59_182702_1	378806.STAUR_8186	1.57e-51	183.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,43BBS@68525|delta/epsilon subdivisions,2X6QY@28221|Deltaproteobacteria,2YU79@29|Myxococcales	28221|Deltaproteobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
k59_359170_1	379731.PST_2955	5e-94	308.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RMU1@1236|Gammaproteobacteria,1Z0SB@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	L	COG1643 HrpA-like helicases	hrpA	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
k59_1651389_1	354242.CJJ81176_1332	1.6e-42	147.0	COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,42QX8@68525|delta/epsilon subdivisions,2YP1G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH2	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
k59_1651389_2	332101.JIBU02000013_gene1277	3.91e-33	124.0	COG0037@1|root,COG0037@2|Bacteria,1V1S0@1239|Firmicutes,24BSC@186801|Clostridia,36GC2@31979|Clostridiaceae	186801|Clostridia	D	tRNA processing	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1535189_1	522306.CAP2UW1_2297	3.15e-65	221.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,2VHJV@28216|Betaproteobacteria,1KPP0@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	D	DNA segregation ATPase FtsK SpoIIIE	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
k59_947729_1	1249480.B649_03965	1.03e-35	139.0	COG1033@1|root,COG1033@2|Bacteria	2|Bacteria	S	growth of symbiont in host cell	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_359205_1	1502770.JQMG01000001_gene392	5.15e-63	212.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,2VH1K@28216|Betaproteobacteria,2KKYH@206350|Nitrosomonadales	206350|Nitrosomonadales	O	TIGRFAM ATP-dependent Clp protease ATP-binding subunit clpA	-	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_359205_2	1502770.JQMG01000001_gene393	2.17e-06	48.5	COG2860@1|root,COG2860@2|Bacteria,1RHQN@1224|Proteobacteria,2VQ70@28216|Betaproteobacteria	28216|Betaproteobacteria	S	UPF0126 domain	-	-	-	-	-	-	-	-	-	-	-	-	UPF0126
k59_359211_1	1249480.B649_11010	5.29e-106	307.0	COG1854@1|root,COG1854@2|Bacteria,1MWQF@1224|Proteobacteria,42QP7@68525|delta/epsilon subdivisions,2YNWJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)	luxS	-	4.4.1.21	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	M00609	R01291	RC00069,RC01929	ko00000,ko00001,ko00002,ko01000	-	-	-	LuxS
k59_359211_2	709032.Sulku_2323	1.03e-50	162.0	2AK1R@1|root,31ARC@2|Bacteria,1Q601@1224|Proteobacteria,42WMW@68525|delta/epsilon subdivisions,2YQ7M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1768665_1	1123517.JOMR01000001_gene1781	1.34e-85	265.0	COG0859@1|root,COG0859@2|Bacteria,1QRJF@1224|Proteobacteria,1RUK1@1236|Gammaproteobacteria,46258@72273|Thiotrichales	72273|Thiotrichales	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
k59_1828921_1	709032.Sulku_2337	1.11e-85	271.0	COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,42P62@68525|delta/epsilon subdivisions,2YNNE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k59_537611_1	1007105.PT7_0009	2.72e-39	140.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,2VHAP@28216|Betaproteobacteria,3T2IH@506|Alcaligenaceae	28216|Betaproteobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
k59_537611_2	159087.Daro_3500	2.14e-96	293.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,2VHJ1@28216|Betaproteobacteria,2KU87@206389|Rhodocyclales	206389|Rhodocyclales	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
k59_9095_1	596154.Alide2_3179	4.53e-73	226.0	COG1179@1|root,COG1179@2|Bacteria,1MWXR@1224|Proteobacteria,2VJPP@28216|Betaproteobacteria,4AAIJ@80864|Comamonadaceae	28216|Betaproteobacteria	H	PFAM UBA THIF-type NAD FAD binding protein	moeB	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
k59_9095_2	1217718.ALOU01000069_gene4772	1.42e-14	72.8	COG2391@1|root,COG2391@2|Bacteria,1MXSE@1224|Proteobacteria,2VKGG@28216|Betaproteobacteria,1K5NZ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
k59_1828931_1	1231391.AMZF01000006_gene2725	8.5e-51	176.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,2VN0V@28216|Betaproteobacteria,3T1JG@506|Alcaligenaceae	28216|Betaproteobacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	cls	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
k59_478136_1	159087.Daro_0602	4.64e-137	390.0	COG0406@1|root,COG0406@2|Bacteria,1NPC4@1224|Proteobacteria,2VQTE@28216|Betaproteobacteria,2KWHE@206389|Rhodocyclales	206389|Rhodocyclales	G	Belongs to the phosphoglycerate mutase family	gpmB	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
k59_1181845_1	1537917.JU82_04565	1.05e-49	160.0	COG1331@1|root,COG1331@2|Bacteria,1QZ2A@1224|Proteobacteria,42VGW@68525|delta/epsilon subdivisions,2YQEQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH,Thioredoxin_7
k59_710662_1	1537915.JU57_06725	1.19e-08	55.1	COG0517@1|root,COG1208@1|root,COG0517@2|Bacteria,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42MX5@68525|delta/epsilon subdivisions,2YMSQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)	ptmE	-	-	-	-	-	-	-	-	-	-	-	CBS,NTP_transferase
k59_710662_2	32024.JMTI01000035_gene898	7.12e-52	172.0	COG0535@1|root,COG0535@2|Bacteria,1PDXU@1224|Proteobacteria,42NVS@68525|delta/epsilon subdivisions,2YNBB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
k59_182803_1	159087.Daro_0282	1.68e-82	253.0	COG0116@1|root,COG0116@2|Bacteria,1MUQM@1224|Proteobacteria,2VHMY@28216|Betaproteobacteria,2KV05@206389|Rhodocyclales	206389|Rhodocyclales	L	Belongs to the methyltransferase superfamily	-	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
k59_359256_1	1249480.B649_09820	1.79e-88	272.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,42MFT@68525|delta/epsilon subdivisions,2YN9H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Ammonium Transporter	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
k59_888309_1	159087.Daro_4195	1.07e-108	318.0	COG3713@1|root,COG3713@2|Bacteria,1R5JE@1224|Proteobacteria,2VKVW@28216|Betaproteobacteria,2KVV9@206389|Rhodocyclales	206389|Rhodocyclales	M	MltA-interacting protein MipA	-	-	-	-	-	-	-	-	-	-	-	-	MipA
k59_769881_1	395494.Galf_2253	7.19e-111	336.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,2VHEV@28216|Betaproteobacteria,44VHK@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_654997_1	395494.Galf_1874	1.41e-16	73.2	COG2827@1|root,COG2827@2|Bacteria,1N6PA@1224|Proteobacteria,2VWG2@28216|Betaproteobacteria,44W37@713636|Nitrosomonadales	28216|Betaproteobacteria	L	PFAM Excinuclease ABC C subunit domain protein	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
k59_654997_2	395494.Galf_1615	4.67e-173	492.0	COG5001@1|root,COG5001@2|Bacteria,1PJIX@1224|Proteobacteria,2W80Q@28216|Betaproteobacteria,44WA0@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_1828985_2	522306.CAP2UW1_0456	9.77e-09	60.5	2E7QE@1|root,3325V@2|Bacteria,1NESB@1224|Proteobacteria,2VXE0@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1592876_2	563040.Saut_0264	2.19e-92	274.0	COG0529@1|root,COG0529@2|Bacteria,1MX0D@1224|Proteobacteria,42RMI@68525|delta/epsilon subdivisions,2YT53@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
k59_1006780_1	1177154.Y5S_02263	3.25e-18	84.7	COG4965@1|root,COG4965@2|Bacteria,1MUXK@1224|Proteobacteria,1S1QN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Flp pilus assembly protein TadB	tadB	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
k59_1006780_2	1280953.HOC_17289	1.7e-14	73.9	COG4962@1|root,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,2TRNT@28211|Alphaproteobacteria,43WK4@69657|Hyphomonadaceae	28211|Alphaproteobacteria	U	pilus assembly protein, ATPase CpaF	cpaF	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
k59_769898_1	1537917.JU82_04015	8.37e-52	170.0	COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,42MQQ@68525|delta/epsilon subdivisions,2YNAG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	dna polymerase iii	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_655030_1	1121438.JNJA01000003_gene2929	2.04e-25	104.0	COG0033@1|root,COG3357@1|root,COG0033@2|Bacteria,COG3357@2|Bacteria,1MU5S@1224|Proteobacteria,42M9F@68525|delta/epsilon subdivisions,2WJNB@28221|Deltaproteobacteria,2M8DQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	pgm	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_655030_2	614083.AWQR01000022_gene102	1.16e-42	145.0	COG3305@1|root,COG3305@2|Bacteria,1RKBI@1224|Proteobacteria,2VWK7@28216|Betaproteobacteria,4AI0S@80864|Comamonadaceae	28216|Betaproteobacteria	S	Predicted membrane protein (DUF2127)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2127
k59_769917_1	1123326.JFBL01000013_gene379	9.92e-52	179.0	COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,42MX8@68525|delta/epsilon subdivisions,2YN00@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	flaB	GO:0001539,GO:0005575,GO:0005576,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_IN,Flagellin_N
k59_1124049_3	268748.Q58N56_BPPRP	2.25e-12	65.5	4QD0J@10239|Viruses,4R0A5@35237|dsDNA viruses  no RNA stage,4QSK9@28883|Caudovirales,4QNR4@10744|Podoviridae	10744|Podoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1242063_1	760117.JN27_21915	6.24e-81	253.0	COG1493@1|root,COG1493@2|Bacteria,1QWDD@1224|Proteobacteria,2WH4H@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1535353_1	159087.Daro_0056	2.97e-138	394.0	COG0788@1|root,COG0788@2|Bacteria,1MVCF@1224|Proteobacteria,2VIXE@28216|Betaproteobacteria,2KVJ6@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_N
k59_1357402_1	1282876.BAOK01000001_gene3550	1.85e-18	85.5	COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,2TUIC@28211|Alphaproteobacteria,4BS7P@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	P	ATPases associated with a variety of cellular activities	cmpD_1	-	-	ko:K02049,ko:K15578	ko00910,ko02010,map00910,map02010	M00188,M00438	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.16,3.A.1.16.1,3.A.1.17	-	-	ABC_tran
k59_1357402_2	1198232.CYCME_1501	1.79e-103	310.0	COG0600@1|root,COG0600@2|Bacteria,1MU6Q@1224|Proteobacteria,1RPP1@1236|Gammaproteobacteria,4600G@72273|Thiotrichales	72273|Thiotrichales	P	transporter, permease	-	-	-	ko:K15577	ko00910,ko02010,map00910,map02010	M00438	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16.1,3.A.1.16.2	-	-	BPD_transp_1
k59_1477785_1	1249480.B649_06280	4.64e-102	304.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,42MJ0@68525|delta/epsilon subdivisions,2YMCZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Co Zn Cd efflux system component	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux,ZT_dimer
k59_1359190_1	172088.AUGA01000006_gene8211	1.42e-45	167.0	COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MWDY@1224|Proteobacteria,2TTGI@28211|Alphaproteobacteria,3JU7A@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IQ	Phosphate acyltransferases	aas	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
k59_1244351_1	546264.NEIFLAOT_02523	6.43e-95	291.0	COG0332@1|root,COG0332@2|Bacteria,1NAGY@1224|Proteobacteria,2VK97@28216|Betaproteobacteria,2KPY7@206351|Neisseriales	206351|Neisseriales	I	3-oxoacyl-(Acyl carrier protein) synthase III	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III_C
k59_1244351_2	493475.GARC_0108	3.71e-18	82.0	2CE7N@1|root,30Q80@2|Bacteria,1MZ6U@1224|Proteobacteria,1S9FI@1236|Gammaproteobacteria,46B5T@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1244351_3	743720.Psefu_0437	4.81e-84	259.0	COG4990@1|root,COG4990@2|Bacteria,1MVC4@1224|Proteobacteria,1RRWD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4872)	-	-	-	-	-	-	-	-	-	-	-	-	BtrH_N,DUF4872
k59_1126384_1	1304883.KI912532_gene2018	4.8e-07	48.1	COG2350@1|root,COG2350@2|Bacteria,1MZ9Z@1224|Proteobacteria,2VUM7@28216|Betaproteobacteria,2KWK7@206389|Rhodocyclales	206389|Rhodocyclales	S	YCII-related domain	-	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
k59_1126384_2	159087.Daro_2903	9.88e-116	334.0	COG2917@1|root,COG2917@2|Bacteria,1NWIZ@1224|Proteobacteria,2VRHB@28216|Betaproteobacteria,2KVFB@206389|Rhodocyclales	206389|Rhodocyclales	D	probably involved in intracellular septation	ispZ	-	-	ko:K06190	-	-	-	-	ko00000	-	-	-	IspA
k59_1537552_1	1537917.JU82_09175	3.16e-18	78.2	2B10Q@1|root,319PM@2|Bacteria,1Q3G4@1224|Proteobacteria,42X9K@68525|delta/epsilon subdivisions,2YQYY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1537552_2	709032.Sulku_0684	1.62e-88	265.0	COG0847@1|root,COG0847@2|Bacteria,1RGGD@1224|Proteobacteria,42ZIP@68525|delta/epsilon subdivisions,2YRQP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG0847 DNA polymerase III epsilon subunit and related 3'-5'	-	-	2.7.7.7	ko:K02342,ko:K10857	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_890401_1	1288494.EBAPG3_23650	5.47e-62	208.0	COG1523@1|root,COG1523@2|Bacteria,1R7FD@1224|Proteobacteria,2WCZK@28216|Betaproteobacteria,373W8@32003|Nitrosomonadales	28216|Betaproteobacteria	G	Alpha amylase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
k59_1009050_2	56780.SYN_02290	5.17e-05	50.4	COG3941@1|root,COG3941@2|Bacteria,1RC0N@1224|Proteobacteria	1224|Proteobacteria	S	tape measure	-	-	-	-	-	-	-	-	-	-	-	-	PhageMin_Tail
k59_1712121_1	562970.Btus_1230	8.11e-43	159.0	COG3211@1|root,COG3211@2|Bacteria,1UYPE@1239|Firmicutes,4HCRC@91061|Bacilli,278TS@186823|Alicyclobacillaceae	91061|Bacilli	S	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	Cu_amine_oxidN1,DUF839
k59_1537573_1	1537917.JU82_03055	1.3e-70	228.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,42MDZ@68525|delta/epsilon subdivisions,2YMJR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaGprimase_HBD,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
k59_1009062_1	159087.Daro_3778	1.21e-207	595.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,2VJ61@28216|Betaproteobacteria,2KUQ8@206389|Rhodocyclales	206389|Rhodocyclales	S	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_244678_1	1249480.B649_00860	6.83e-21	83.2	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,42TRU@68525|delta/epsilon subdivisions,2YPS3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
k59_244678_2	709032.Sulku_0210	8.14e-116	335.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,42MM5@68525|delta/epsilon subdivisions,2YM98@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
k59_10809_1	1168067.JAGP01000001_gene143	2.04e-186	535.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,1RMJB@1236|Gammaproteobacteria,45ZNP@72273|Thiotrichales	72273|Thiotrichales	T	GTP-binding protein TypA	-	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
k59_723207_1	85643.Tmz1t_3631	4.94e-114	335.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,2VJ1W@28216|Betaproteobacteria,2KUD2@206389|Rhodocyclales	206389|Rhodocyclales	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
k59_723207_2	159087.Daro_3732	4.1e-112	323.0	COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,2VKKJ@28216|Betaproteobacteria,2KVUE@206389|Rhodocyclales	206389|Rhodocyclales	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
k59_614394_1	998088.B565_0866	1.81e-84	258.0	COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,1RMFG@1236|Gammaproteobacteria,1Y3H9@135624|Aeromonadales	135624|Aeromonadales	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
k59_614394_2	1298608.JCM18900_1535	7.91e-23	95.5	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,3NJVZ@468|Moraxellaceae	1236|Gammaproteobacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysM	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.47	ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	iECP_1309.ECP_2444	PALP
k59_1144066_1	398767.Glov_0187	2.42e-48	167.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the peptidase S1C family	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
k59_314327_1	387093.SUN_1148	2.11e-55	191.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,42NAX@68525|delta/epsilon subdivisions,2YN4X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
k59_374735_1	1227739.Hsw_0669	3.21e-08	62.8	COG4775@1|root,COG4775@2|Bacteria,4NF38@976|Bacteroidetes,47KMS@768503|Cytophagia	976|Bacteroidetes	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_788288_1	395494.Galf_2569	6.3e-72	229.0	COG3287@1|root,COG3287@2|Bacteria,1QUQH@1224|Proteobacteria,2VMN2@28216|Betaproteobacteria,44WBJ@713636|Nitrosomonadales	28216|Betaproteobacteria	S	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
k59_1029787_1	1537917.JU82_11220	1.17e-81	249.0	COG1651@1|root,COG1651@2|Bacteria,1RFRJ@1224|Proteobacteria,42SPD@68525|delta/epsilon subdivisions,2YP88@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
k59_1029787_2	1249480.B649_07730	7.59e-41	139.0	COG3030@1|root,COG3030@2|Bacteria,1N2HX@1224|Proteobacteria,42TXA@68525|delta/epsilon subdivisions,2YQ5J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	FxsA cytoplasmic membrane protein	-	-	2.3.3.13	ko:K01649,ko:K07113	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	FxsA
k59_434874_1	1537917.JU82_11060	7.71e-47	155.0	COG0125@1|root,COG0125@2|Bacteria,1R98D@1224|Proteobacteria,43B5Z@68525|delta/epsilon subdivisions,2YP5N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
k59_966563_2	1348657.M622_00225	1.08e-27	117.0	COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,2VPB3@28216|Betaproteobacteria,2KVVY@206389|Rhodocyclales	206389|Rhodocyclales	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_4,TPR_8
k59_23128_1	827.JFJK01000009_gene1378	1.42e-76	229.0	COG0048@1|root,COG0048@2|Bacteria,1RCWY@1224|Proteobacteria,42RDQ@68525|delta/epsilon subdivisions,2YP65@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
k59_23128_2	387093.SUN_0132	1.5e-06	49.3	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2YMP9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5,RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_1609360_1	1249480.B649_10430	7.65e-90	276.0	COG1757@1|root,COG1757@2|Bacteria,1MY5C@1224|Proteobacteria,42P0P@68525|delta/epsilon subdivisions,2YN3S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Na H antiporter	nhaC	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
k59_559211_1	709032.Sulku_0089	1.54e-82	256.0	COG3174@1|root,COG3174@2|Bacteria,1NDBI@1224|Proteobacteria,42QBM@68525|delta/epsilon subdivisions,2YNPT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	MgtC family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
k59_966620_1	1249480.B649_02890	8.29e-124	358.0	COG1847@1|root,COG1847@2|Bacteria,1RB1P@1224|Proteobacteria,42QYV@68525|delta/epsilon subdivisions,2YNW5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Jag_N	-	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N
k59_966620_2	709032.Sulku_0580	1.04e-34	129.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,42M6T@68525|delta/epsilon subdivisions,2YMJD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
k59_1198217_1	709032.Sulku_2050	1.81e-107	313.0	COG1969@1|root,COG1969@2|Bacteria,1MU87@1224|Proteobacteria,42NQ3@68525|delta/epsilon subdivisions,2YMRF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Ni Fe-hydrogenase, b-type cytochrome subunit	-	-	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
k59_259630_1	159087.Daro_1763	2.31e-115	355.0	COG0247@1|root,COG0277@1|root,COG1145@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,COG1145@2|Bacteria,1MU6Y@1224|Proteobacteria,2VHCG@28216|Betaproteobacteria,2KVGQ@206389|Rhodocyclales	206389|Rhodocyclales	C	FAD linked oxidases, C-terminal domain	-	-	-	ko:K18930	-	-	-	-	ko00000	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_7
k59_1492523_2	580332.Slit_0886	3.24e-75	230.0	COG1433@1|root,COG1433@2|Bacteria,1PW6J@1224|Proteobacteria,2WFJ3@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Pfam Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	DIMCO_N,Nitro_FeMo-Co
k59_145874_1	709032.Sulku_1987	5.61e-80	247.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,42N2T@68525|delta/epsilon subdivisions,2YNID@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	acid membrane antigen A	amaA	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k59_314384_1	709032.Sulku_1117	1.26e-76	247.0	COG2197@1|root,COG4191@1|root,COG2197@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42R06@68525|delta/epsilon subdivisions,2YP00@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9
k59_966651_1	1169144.KB910984_gene3849	1.3e-46	167.0	COG3227@1|root,COG3227@2|Bacteria,1TP08@1239|Firmicutes,4H9S6@91061|Bacilli,1ZCEP@1386|Bacillus	91061|Bacilli	E	Peptidase M4	npr	GO:0005575,GO:0005576	3.4.24.28	ko:K01400	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	FTP,PepSY,Peptidase_M4,Peptidase_M4_C
k59_1375309_2	944546.ABED_0555	7.69e-34	121.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria	1224|Proteobacteria	NT	Methyl-accepting chemotaxis protein	-	-	-	ko:K03406,ko:K03776	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	PAS_3
k59_676217_1	1249480.B649_05800	4.72e-104	325.0	COG0659@1|root,COG0664@1|root,COG0659@2|Bacteria,COG0664@2|Bacteria,1MVWV@1224|Proteobacteria,42MMU@68525|delta/epsilon subdivisions,2YTMR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	STAS domain	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp,cNMP_binding
k59_145891_1	411490.ANACAC_03634	3.45e-50	179.0	COG0072@1|root,COG0072@2|Bacteria,1TP98@1239|Firmicutes,248BJ@186801|Clostridia	186801|Clostridia	J	phenylalanyl-tRNA synthetase (beta subunit)	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA-synt_2d,tRNA_bind
k59_314395_2	1132855.KB913035_gene1643	4.24e-92	285.0	COG0579@1|root,COG0579@2|Bacteria,1MUCC@1224|Proteobacteria,2VHAA@28216|Betaproteobacteria,2KKZS@206350|Nitrosomonadales	206350|Nitrosomonadales	C	malate quinone oxidoreductase	mqo	-	1.1.5.4	ko:K00116	ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00009,M00011	R00360,R00361,R01257	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Mqo
k59_1785568_1	716928.AJQT01000024_gene3238	1.46e-105	318.0	COG1027@1|root,COG1027@2|Bacteria,1R9JY@1224|Proteobacteria,2TVZD@28211|Alphaproteobacteria,4BCBC@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Aspartate ammonia-lyase	aspA	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1
k59_1609436_1	159087.Daro_0483	5.02e-61	189.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,2VR2Z@28216|Betaproteobacteria,2KWHT@206389|Rhodocyclales	206389|Rhodocyclales	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
k59_1438879_1	1249627.D779_1985	4.04e-62	211.0	COG4774@1|root,COG4774@2|Bacteria,1QU2Y@1224|Proteobacteria,1T1NS@1236|Gammaproteobacteria,1WZRX@135613|Chromatiales	1236|Gammaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_1029951_1	709032.Sulku_0080	1.18e-183	514.0	COG0301@1|root,COG0301@2|Bacteria,1N1R1@1224|Proteobacteria,42MQ9@68525|delta/epsilon subdivisions,2YTBB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Arginosuccinate synthase	-	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	Arginosuc_synth,ThiI,tRNA_Me_trans
k59_559319_1	305700.B447_04227	3.16e-79	244.0	COG0535@1|root,COG0535@2|Bacteria,1MU07@1224|Proteobacteria,2VKSA@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3641)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3641,Fer4_12,Radical_SAM
k59_1263386_1	640081.Dsui_0412	1.54e-75	233.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2VKRD@28216|Betaproteobacteria,2M00Y@206389|Rhodocyclales	206389|Rhodocyclales	P	ABC-type dipeptide oligopeptide nickel transport	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
k59_1263386_2	640081.Dsui_0413	2.73e-10	60.1	COG1173@1|root,COG1173@2|Bacteria,1MW3R@1224|Proteobacteria,2WEQ6@28216|Betaproteobacteria,2KZVD@206389|Rhodocyclales	206389|Rhodocyclales	P	ABC-type dipeptide oligopeptide nickel transport	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
k59_1556471_2	159087.Daro_3537	6.28e-154	434.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,2VNAX@28216|Betaproteobacteria,2KVVS@206389|Rhodocyclales	206389|Rhodocyclales	I	Acyltransferase	nlaB	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k59_1492602_1	1165841.SULAR_05578	1.07e-22	89.0	COG1758@1|root,COG1758@2|Bacteria,1Q28G@1224|Proteobacteria,42V5Z@68525|delta/epsilon subdivisions,2YQDH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
k59_1492602_2	1165841.SULAR_05583	1.64e-135	387.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,42M3X@68525|delta/epsilon subdivisions,2YMCQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
k59_435045_1	1537917.JU82_02320	3.96e-05	44.7	COG1287@1|root,COG1287@2|Bacteria,1R8YG@1224|Proteobacteria,43BIB@68525|delta/epsilon subdivisions,2YT8Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Oligosaccharide transferase	-	-	2.4.99.18	ko:K07151	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	STT3
k59_435045_2	709032.Sulku_2414	2.58e-44	160.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,42MMR@68525|delta/epsilon subdivisions,2YMF0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	GM	Polysaccharide biosynthesis protein	pglF	-	4.2.1.135	ko:K15912	ko00520,map00520	-	-	-	ko00000,ko00001,ko01000	-	-	-	Polysacc_synt_2
k59_1263427_1	1132855.KB913035_gene2120	1.53e-37	128.0	COG1393@1|root,COG1393@2|Bacteria,1MZ6S@1224|Proteobacteria,2VUB7@28216|Betaproteobacteria,2KMXQ@206350|Nitrosomonadales	206350|Nitrosomonadales	P	Belongs to the ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	ArsC
k59_1263427_2	1502770.JQMG01000001_gene141	3.77e-50	169.0	COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,2VHRF@28216|Betaproteobacteria,2KMC3@206350|Nitrosomonadales	206350|Nitrosomonadales	E	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
k59_1312848_1	1537917.JU82_05020	5.38e-68	221.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1RGCV@1224|Proteobacteria,42M47@68525|delta/epsilon subdivisions,2YMRS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	(EAL) domain protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_1263431_1	666681.M301_2191	1.55e-47	157.0	COG1525@1|root,COG1525@2|Bacteria,1N145@1224|Proteobacteria,2VUA6@28216|Betaproteobacteria,2KN3G@206350|Nitrosomonadales	206350|Nitrosomonadales	L	Staphylococcal nuclease homologues	-	-	-	-	-	-	-	-	-	-	-	-	SNase
k59_374898_2	1249480.B649_03840	8.14e-113	343.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42PTS@68525|delta/epsilon subdivisions,2YNBM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_723379_1	159087.Daro_2368	2.42e-77	241.0	COG0332@1|root,COG0332@2|Bacteria,1NAGY@1224|Proteobacteria,2VK97@28216|Betaproteobacteria,2KV2E@206389|Rhodocyclales	206389|Rhodocyclales	I	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III_C
k59_723379_2	1304883.KI912532_gene2552	8.83e-11	58.5	2CE7N@1|root,30Q80@2|Bacteria,1MZ6U@1224|Proteobacteria,2VSFG@28216|Betaproteobacteria,2KWUH@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_23274_1	1265502.KB905940_gene2986	1.73e-46	164.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,2VHBA@28216|Betaproteobacteria,4A9VS@80864|Comamonadaceae	28216|Betaproteobacteria	S	CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
k59_559430_1	1304885.AUEY01000003_gene474	3.55e-17	87.0	COG0515@1|root,COG0642@1|root,COG3899@1|root,COG5002@1|root,COG0515@2|Bacteria,COG0642@2|Bacteria,COG3899@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,42NK9@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Response regulator receiver	-	-	2.7.13.3	ko:K07678	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	AAA_16,GAF,HAMP,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_8,PAS_9,Pkinase,Response_reg,SBP_bac_3
k59_1785677_1	387093.SUN_1903	5.23e-14	76.6	COG2198@1|root,COG2198@2|Bacteria	2|Bacteria	T	Histidine kinase	rcsD	GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009927,GO:0009987,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0031224,GO:0031226,GO:0035556,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0071704,GO:0071944,GO:0140096,GO:1901564	2.7.13.3	ko:K07676,ko:K10715,ko:K20976	ko02020,ko02024,ko02025,ko02026,map02020,map02024,map02025,map02026	M00474,M00517,M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Hpt,RcsD_ABL,Response_reg
k59_497687_1	709032.Sulku_1282	2.36e-70	235.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2YNMM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.6,3.6.3.8	ko:K01535,ko:K01537	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.3.2,3.A.3.3	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
k59_559436_1	709032.Sulku_2413	6.83e-71	234.0	COG1287@1|root,COG1287@2|Bacteria,1R481@1224|Proteobacteria,42MNZ@68525|delta/epsilon subdivisions,2YMU3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Oligosaccharyl transferase, STT3 subunit	pglB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0034645,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046872,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.4.99.18,2.4.99.19	ko:K07151,ko:K17251	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	STT3
k59_79971_1	491205.JARQ01000006_gene2864	9.06e-77	235.0	COG0693@1|root,COG0693@2|Bacteria,4NFQE@976|Bacteroidetes,1IHB5@117743|Flavobacteriia,3ZTTI@59732|Chryseobacterium	976|Bacteroidetes	S	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
k59_614752_1	358220.C380_23675	2.03e-78	246.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,2VHHS@28216|Betaproteobacteria,4AAUW@80864|Comamonadaceae	28216|Betaproteobacteria	M	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3,SurA_N
k59_614752_2	358220.C380_23675	1.03e-14	72.8	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,2VHHS@28216|Betaproteobacteria,4AAUW@80864|Comamonadaceae	28216|Betaproteobacteria	M	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3,SurA_N
k59_1033327_1	1249480.B649_06140	4.82e-84	274.0	COG2982@1|root,COG2982@2|Bacteria,1QA6E@1224|Proteobacteria,42NCN@68525|delta/epsilon subdivisions,2YM89@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_1,DUF3971
k59_1033327_2	877424.ATWC01000058_gene2235	2.34e-07	52.4	COG2200@1|root,COG2200@2|Bacteria,1TS8B@1239|Firmicutes,24EZ4@186801|Clostridia,27JIK@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_4,PAS_9
k59_1559506_1	709032.Sulku_0147	7.43e-95	283.0	COG0300@1|root,COG0300@2|Bacteria,1RAFB@1224|Proteobacteria,42RPR@68525|delta/epsilon subdivisions,2YPAJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_725179_1	1452718.JBOY01000015_gene814	7.21e-71	231.0	COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,1RMFY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113,GO:2000765,GO:2000766	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
k59_1787903_1	1121447.JONL01000001_gene1076	1.73e-48	177.0	COG0834@1|root,COG2199@1|root,COG0834@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42MCD@68525|delta/epsilon subdivisions,2X5DF@28221|Deltaproteobacteria,2MG1M@213115|Desulfovibrionales	28221|Deltaproteobacteria	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,NMT1,SBP_bac_3
k59_1559532_1	709032.Sulku_0383	2.83e-34	118.0	COG3093@1|root,COG3093@2|Bacteria,1N76J@1224|Proteobacteria,42U2H@68525|delta/epsilon subdivisions,2YQJH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	XRE family	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
k59_1559532_2	709032.Sulku_0382	4.5e-56	176.0	COG3549@1|root,COG3549@2|Bacteria,1MZKX@1224|Proteobacteria,42VG7@68525|delta/epsilon subdivisions,2YQNI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COGs COG3549 Plasmid maintenance system killer protein	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
k59_1729814_1	709032.Sulku_0167	8.31e-35	128.0	COG1459@1|root,COG1459@2|Bacteria	2|Bacteria	U	protein transport across the cell outer membrane	-	-	-	ko:K02455,ko:K12510	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
k59_1729814_2	709032.Sulku_0168	2.17e-152	441.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2YMIX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	ctsE	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
k59_1315323_1	243231.GSU0792	2.32e-60	196.0	COG3332@1|root,COG3332@2|Bacteria,1RDBS@1224|Proteobacteria,42QS8@68525|delta/epsilon subdivisions,2WMV7@28221|Deltaproteobacteria,43SGZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Transport and Golgi organisation 2	-	-	-	-	-	-	-	-	-	-	-	-	TANGO2
k59_1853124_1	709032.Sulku_2316	2.53e-114	345.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,42KZC@68525|delta/epsilon subdivisions,2YM82@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
k59_376908_1	709032.Sulku_0532	6.81e-104	305.0	COG2231@1|root,COG2231@2|Bacteria,1RDJ8@1224|Proteobacteria,42QYA@68525|delta/epsilon subdivisions,2YP2S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	endonuclease III	magIII	-	-	ko:K07457	-	-	-	-	ko00000	-	-	-	HhH-GPD
k59_1377673_1	709032.Sulku_1742	1.12e-85	272.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42PTS@68525|delta/epsilon subdivisions,2YNBM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_1266497_1	1176165.CAJD01000011_gene585	1.59e-10	66.6	COG0500@1|root,COG2226@2|Bacteria,2GKFZ@201174|Actinobacteria,4F8D0@85019|Brevibacteriaceae	201174|Actinobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044424,GO:0044464,GO:0071944	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
k59_562503_1	870187.Thini_4255	7.45e-93	284.0	COG3350@1|root,COG3350@2|Bacteria,1MWWK@1224|Proteobacteria,1S10I@1236|Gammaproteobacteria,4621E@72273|Thiotrichales	72273|Thiotrichales	S	YHS domain	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_Hydrox,YHS
k59_562503_2	497321.C664_16410	4.63e-16	71.2	2BXCC@1|root,32VH7@2|Bacteria,1N1P7@1224|Proteobacteria,2WCYY@28216|Betaproteobacteria,2KZ42@206389|Rhodocyclales	206389|Rhodocyclales	C	Toluene-4-monooxygenase system protein B (TmoB)	-	-	1.14.13.236	ko:K15761	ko00623,ko01100,ko01120,ko01220,map00623,map01100,map01120,map01220	M00538	R02550,R03562,R05666	RC00269,RC00490	ko00000,ko00001,ko00002,ko01000	-	-	-	TmoB
k59_907553_1	1150621.SMUL_0993	2.98e-52	172.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,42M98@68525|delta/epsilon subdivisions,2YPXH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
k59_500982_1	1132855.KB913035_gene1282	7.21e-71	239.0	COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VJSZ@28216|Betaproteobacteria,2KKGJ@206350|Nitrosomonadales	206350|Nitrosomonadales	T	response regulator receiver	-	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,HATPase_c,Hpt,Response_reg
k59_1671309_1	558884.JRGM01000190_gene1	1.94e-25	107.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria	1224|Proteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HCBP_related,HemolysinCabind
k59_1377715_1	377629.TERTU_4161	5.9e-96	298.0	COG0515@1|root,COG0631@1|root,COG0515@2|Bacteria,COG0631@2|Bacteria,1MV1P@1224|Proteobacteria,1RNQN@1236|Gammaproteobacteria,2PN9G@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	T	Lipopolysaccharide kinase (Kdo/WaaP) family	-	-	3.1.3.16	ko:K01090,ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2,Pkinase
k59_1147535_1	1132855.KB913035_gene885	1.71e-69	239.0	COG0642@1|root,COG2203@1|root,COG3829@1|root,COG5002@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria,2KNFH@206350|Nitrosomonadales	206350|Nitrosomonadales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
k59_82100_1	62928.azo1390	1.93e-111	329.0	COG0226@1|root,COG0226@2|Bacteria,1MUAZ@1224|Proteobacteria,2VIJV@28216|Betaproteobacteria,2KVUC@206389|Rhodocyclales	206389|Rhodocyclales	P	Part of the ABC transporter complex PstSACB involved in phosphate import	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
k59_618052_1	1537917.JU82_08305	2.13e-108	325.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,42MK9@68525|delta/epsilon subdivisions,2YNM1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	ATPase related to phosphate starvation-inducible protein PhoH	phoH	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
k59_618067_1	553218.CAMRE0001_1179	1.05e-40	144.0	COG3043@1|root,COG3043@2|Bacteria,1NAZB@1224|Proteobacteria,42SN1@68525|delta/epsilon subdivisions,2YPF9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB	napB	-	-	ko:K02568	ko00910,ko01120,map00910,map01120	M00529,M00530	R00798	RC02812	ko00000,ko00001,ko00002	-	-	-	NapB
k59_1315421_1	640081.Dsui_2250	8.79e-82	255.0	COG2206@1|root,COG3437@1|root,COG2206@2|Bacteria,COG3437@2|Bacteria,1R53C@1224|Proteobacteria,2VNCZ@28216|Betaproteobacteria,2KW0J@206389|Rhodocyclales	206389|Rhodocyclales	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
k59_725268_1	1304883.KI912532_gene857	1.02e-38	136.0	COG0671@1|root,COG0671@2|Bacteria,1RFUF@1224|Proteobacteria,2VRMF@28216|Betaproteobacteria,2KWEU@206389|Rhodocyclales	206389|Rhodocyclales	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2,PAP2_3
k59_1200778_1	1123514.KB905899_gene1763	7e-52	187.0	COG0840@1|root,COG5001@1|root,COG0840@2|Bacteria,COG5001@2|Bacteria,1QX3B@1224|Proteobacteria,1T35M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_1266596_1	159087.Daro_2176	1.77e-121	359.0	COG3517@1|root,COG3517@2|Bacteria,1MU5C@1224|Proteobacteria,2VKCP@28216|Betaproteobacteria,2KUA6@206389|Rhodocyclales	206389|Rhodocyclales	S	This family consists of a number of uncharacterised bacterial proteins. The function of this family is	-	-	-	ko:K11900	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	VipB
k59_1033511_1	1157490.EL26_15635	6.46e-65	218.0	COG3290@1|root,COG3829@1|root,COG3290@2|Bacteria,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HADT@91061|Bacilli,27813@186823|Alicyclobacillaceae	91061|Bacilli	KT	Sigma-54 interaction domain	bkdR	-	-	-	-	-	-	-	-	-	-	-	DapB_N,HTH_8,PAS,Sigma54_activat
k59_1513292_1	709032.Sulku_1054	5.32e-33	122.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,42N1R@68525|delta/epsilon subdivisions,2YMRZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_1513292_2	1442598.JABW01000026_gene1195	3.47e-40	133.0	COG3205@1|root,COG3205@2|Bacteria,1NA8W@1224|Proteobacteria,42W08@68525|delta/epsilon subdivisions,2YQND@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Predicted membrane protein (DUF2061)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2061
k59_928150_1	159087.Daro_3075	1.86e-177	507.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2VJ55@28216|Betaproteobacteria,2KUZP@206389|Rhodocyclales	206389|Rhodocyclales	H	COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase	ilvI	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_393858_1	1304883.KI912532_gene448	8.5e-144	422.0	COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,2WGG3@28216|Betaproteobacteria,2KV1E@206389|Rhodocyclales	206389|Rhodocyclales	O	COG5265 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k59_1053905_1	709032.Sulku_0658	5.15e-152	442.0	COG2199@1|root,COG2199@2|Bacteria,1QTZT@1224|Proteobacteria,43E8E@68525|delta/epsilon subdivisions,2YN2B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_700240_1	159087.Daro_4119	1.04e-54	185.0	2A8Z1@1|root,30Y2U@2|Bacteria,1PJYG@1224|Proteobacteria,2VJ83@28216|Betaproteobacteria,2KVGT@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_700241_1	1537917.JU82_11055	6.44e-86	264.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,42MG0@68525|delta/epsilon subdivisions,2YMII@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
k59_700241_2	1537917.JU82_11050	3.98e-08	53.5	COG1166@1|root,COG1166@2|Bacteria,1MU80@1224|Proteobacteria,42M2B@68525|delta/epsilon subdivisions,2YMP0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	arginine decarboxylase	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0422	Orn_Arg_deC_N
k59_393920_1	395493.BegalDRAFT_1840	2.25e-72	226.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,1RM8I@1236|Gammaproteobacteria,4608G@72273|Thiotrichales	72273|Thiotrichales	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
k59_991992_2	1249480.B649_10710	1.12e-98	288.0	COG0244@1|root,COG0244@2|Bacteria,1RB0Y@1224|Proteobacteria,43B5K@68525|delta/epsilon subdivisions,2YPHB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
k59_1103754_1	1304883.KI912532_gene3029	4.02e-71	218.0	COG2878@1|root,COG2878@2|Bacteria,1MUWU@1224|Proteobacteria,2VN5I@28216|Betaproteobacteria,2KVNK@206389|Rhodocyclales	206389|Rhodocyclales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4_21
k59_1103754_2	1304883.KI912532_gene3030	6.11e-29	114.0	COG4656@1|root,COG4656@2|Bacteria,1PJVF@1224|Proteobacteria,2VM4P@28216|Betaproteobacteria,2KUV4@206389|Rhodocyclales	206389|Rhodocyclales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,Fer4_17,RnfC_N,SLBB
k59_1631940_1	349521.HCH_05790	2.41e-05	47.0	COG0748@1|root,COG0748@2|Bacteria,1REH2@1224|Proteobacteria,1T0AC@1236|Gammaproteobacteria,1XKUH@135619|Oceanospirillales	135619|Oceanospirillales	P	Pfam:Pyridox_oxidase	-	-	-	ko:K07226	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
k59_928290_1	946483.Cenrod_1152	2.63e-40	153.0	COG2202@1|root,COG4251@1|root,COG5001@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,4AD7J@80864|Comamonadaceae	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	CZB,EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
k59_1167142_1	946483.Cenrod_2588	3.4e-35	139.0	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1NC9X@1224|Proteobacteria,2WGIN@28216|Betaproteobacteria,4AJX3@80864|Comamonadaceae	28216|Betaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,PAS_4,Response_reg
k59_812345_1	335283.Neut_1545	1.9e-117	347.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,2VHF7@28216|Betaproteobacteria,3723P@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,S4_2,tRNA-synt_1b
k59_1461944_1	1172190.M947_10265	3.11e-94	292.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,42MEQ@68525|delta/epsilon subdivisions,2YMGS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	COG0058 Glucan phosphorylase	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
k59_1461944_2	944481.JAFP01000001_gene971	4.93e-10	61.2	COG1940@1|root,COG1940@2|Bacteria,1MU94@1224|Proteobacteria,42S50@68525|delta/epsilon subdivisions,2X5NZ@28221|Deltaproteobacteria,2M78F@213113|Desulfurellales	28221|Deltaproteobacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
k59_1167158_1	188350.Q8H9S6_9CAUD	1.54e-13	73.9	4QGE6@10239|Viruses	10239|Viruses	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_637222_1	159087.Daro_1226	3.24e-108	317.0	COG0546@1|root,COG0546@2|Bacteria,1RCXJ@1224|Proteobacteria,2VS13@28216|Betaproteobacteria,2KWJQ@206389|Rhodocyclales	206389|Rhodocyclales	S	HAD-hyrolase-like	-	-	3.1.3.105	ko:K22292	ko00520,map00520	-	R11785	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_1805525_1	709032.Sulku_0380	5.91e-53	170.0	COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,42TM2@68525|delta/epsilon subdivisions,2YPMC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
k59_455944_1	1249480.B649_00540	4.06e-96	292.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,42PEH@68525|delta/epsilon subdivisions,2YTDD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	-Amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
k59_866072_1	1123054.KB907753_gene2595	0.000205	44.7	COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,1RMF9@1236|Gammaproteobacteria,1WZPM@135613|Chromatiales	135613|Chromatiales	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_333612_1	387093.SUN_0109	2.13e-48	160.0	COG1427@1|root,COG1427@2|Bacteria,1RCS0@1224|Proteobacteria,42MJZ@68525|delta/epsilon subdivisions,2YN8T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
k59_333612_2	1165841.SULAR_10464	1.57e-50	172.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,42MAI@68525|delta/epsilon subdivisions,2YMCW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	iIT341.HP0476	tRNA-synt_1c
k59_928384_1	1537917.JU82_01960	7.1e-102	307.0	COG3347@1|root,COG3347@2|Bacteria,1QVWU@1224|Proteobacteria,43CKY@68525|delta/epsilon subdivisions,2YNA2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	IQ	PFAM Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
k59_928384_2	1537917.JU82_01965	6.1e-17	73.9	COG1359@1|root,COG1359@2|Bacteria,1NGPW@1224|Proteobacteria,42UUW@68525|delta/epsilon subdivisions,2YQ5Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
k59_518944_1	387093.SUN_1046	2.62e-93	290.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,42M3D@68525|delta/epsilon subdivisions,2YMAA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
k59_1219998_1	709032.Sulku_0529	1.92e-108	332.0	COG0726@1|root,COG1649@1|root,COG0726@2|Bacteria,COG1649@2|Bacteria,1MWR2@1224|Proteobacteria,43AG1@68525|delta/epsilon subdivisions,2YT1V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Hypothetical glycosyl hydrolase family 13	-	-	-	ko:K11931	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000	-	-	-	GHL13,Polysacc_deac_1
k59_1103848_1	1249480.B649_04795	4.16e-97	307.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2YMQV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_1103853_1	709032.Sulku_2257	1.16e-91	280.0	COG0642@1|root,COG2205@2|Bacteria,1Q179@1224|Proteobacteria,4313A@68525|delta/epsilon subdivisions,2YS9S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07645	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	-
k59_394125_1	1123393.KB891317_gene2318	1.57e-38	135.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,2VKD4@28216|Betaproteobacteria,1KS0Z@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Multi-copper polyphenol oxidoreductase laccase	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
k59_394125_2	339670.Bamb_1731	1.28e-25	104.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,2VIFF@28216|Betaproteobacteria,1JZYN@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_333659_1	709032.Sulku_0623	2.07e-159	466.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42YH8@68525|delta/epsilon subdivisions,2YRAU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
k59_741091_1	640081.Dsui_0638	7.76e-115	332.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,2VHIC@28216|Betaproteobacteria,2KUY5@206389|Rhodocyclales	206389|Rhodocyclales	E	ABC-type polar amino acid transport system, ATPase component	-	-	-	ko:K10004	ko02010,ko02020,map02010,map02020	M00230	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3.19,3.A.1.3.4	-	-	ABC_tran
k59_1750401_1	709032.Sulku_1515	2.19e-120	345.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,42MFU@68525|delta/epsilon subdivisions,2YMBZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	-	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
k59_456038_1	1537917.JU82_07280	2.6e-93	282.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,42MXF@68525|delta/epsilon subdivisions,2YMJ8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Mur ligase middle domain	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
k59_280044_1	756272.Plabr_1192	1.25e-103	315.0	COG0056@1|root,COG0056@2|Bacteria,2IXN5@203682|Planctomycetes	203682|Planctomycetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_42507_1	1249480.B649_07430	2.58e-72	219.0	COG0537@1|root,COG0537@2|Bacteria,1RHYQ@1224|Proteobacteria,42SEG@68525|delta/epsilon subdivisions,2YNWN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	FG	HIT family	-	-	-	-	-	-	-	-	-	-	-	-	HIT
k59_42507_2	223926.28805750	3.84e-05	45.8	COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1N6EM@1224|Proteobacteria,1SBXG@1236|Gammaproteobacteria,1XU00@135623|Vibrionales	135623|Vibrionales	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA,OmpA_membrane
k59_741138_1	1304883.KI912532_gene3068	2.18e-46	164.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,2VHXG@28216|Betaproteobacteria,2KUSZ@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
k59_741138_2	159087.Daro_3062	9.91e-74	227.0	COG1469@1|root,COG1469@2|Bacteria,1MV1B@1224|Proteobacteria,2VIC9@28216|Betaproteobacteria,2KV79@206389|Rhodocyclales	206389|Rhodocyclales	S	Converts GTP to 7,8-dihydroneopterin triphosphate	folE2	-	3.5.4.16	ko:K09007	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GCHY-1
k59_1872227_1	1249480.B649_09935	1.22e-71	227.0	COG0438@1|root,COG0438@2|Bacteria,1QFQQ@1224|Proteobacteria,42Q8D@68525|delta/epsilon subdivisions,2YMC5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Glycosyl transferases group 1	pglH1	-	2.4.1.292	ko:K17249	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
k59_1750459_1	1249480.B649_02780	1.29e-67	219.0	COG0642@1|root,COG0642@2|Bacteria,1N5IQ@1224|Proteobacteria,42M9P@68525|delta/epsilon subdivisions,2YN0U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	cprS	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
k59_1872234_1	1304883.KI912532_gene1287	5.55e-124	376.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KV1U@206389|Rhodocyclales	206389|Rhodocyclales	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_9,Protoglobin
k59_42538_1	153948.NAL212_2521	8.29e-46	149.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,2VSKJ@28216|Betaproteobacteria,373D1@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
k59_42538_2	395494.Galf_2637	1.64e-49	167.0	COG2070@1|root,COG2070@2|Bacteria,1N52W@1224|Proteobacteria,2VJ45@28216|Betaproteobacteria,44VCF@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Nitronate monooxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
k59_928575_1	709032.Sulku_1894	8.61e-144	410.0	COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,42NSS@68525|delta/epsilon subdivisions,2YNZK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
k59_1220101_1	338969.Rfer_2881	7.17e-52	181.0	COG5492@1|root,COG5492@2|Bacteria,1QY8X@1224|Proteobacteria,2VJ6A@28216|Betaproteobacteria	28216|Betaproteobacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_456111_1	1167006.UWK_02147	8.88e-07	54.3	COG1835@1|root,COG1835@2|Bacteria,1PHRK@1224|Proteobacteria,43AB1@68525|delta/epsilon subdivisions,2X164@28221|Deltaproteobacteria,2MNZN@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
k59_456111_2	1249480.B649_11725	2.37e-52	178.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,42NBJ@68525|delta/epsilon subdivisions,2YMTY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Mg chelatase-related protein	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
k59_1750485_1	1249480.B649_01175	2.72e-79	259.0	COG1034@1|root,COG1034@2|Bacteria,1RCFT@1224|Proteobacteria,42NK4@68525|delta/epsilon subdivisions,2YNI6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G)	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4,Fer4_7,NADH-G_4Fe-4S_3
k59_928599_1	159087.Daro_2338	7.9e-104	313.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,2VH9X@28216|Betaproteobacteria,2KVFJ@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
k59_928605_1	1178482.BJB45_18845	2.67e-12	72.0	COG1361@1|root,COG2304@1|root,COG2373@1|root,COG2931@1|root,COG3210@1|root,COG1361@2|Bacteria,COG2304@2|Bacteria,COG2373@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	ko:K11005	-	-	-	-	ko00000,ko02000,ko02042	1.C.11	-	-	Big_3_2,Cadherin_3,Calx-beta,DUF5011,He_PIG,HemolysinCabind,OmpA_membrane,PPC,RTX,RTX_C,TSP_3,VWA_2,fn3
k59_1167421_1	709032.Sulku_2495	3.61e-204	569.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,42NR0@68525|delta/epsilon subdivisions,2YRAH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	ParA
k59_741202_1	709032.Sulku_0932	3.79e-95	283.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,42M0X@68525|delta/epsilon subdivisions,2YN2X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
k59_741202_2	709032.Sulku_0933	2.05e-17	80.9	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42N0H@68525|delta/epsilon subdivisions,2YMMP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the peptidase M16 family	pqqL	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_1632206_1	1235457.C404_14915	9.64e-106	320.0	COG2433@1|root,COG2433@2|Bacteria,1RJ1Q@1224|Proteobacteria,2VKSJ@28216|Betaproteobacteria,1KG5R@119060|Burkholderiaceae	28216|Betaproteobacteria	S	transposase IS66	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
k59_1462164_1	1537917.JU82_08040	1.93e-95	300.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2YMW4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_812589_1	1165841.SULAR_07770	1.27e-36	136.0	COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,42P71@68525|delta/epsilon subdivisions,2YNAA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Phospholipid glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5,Acyltransferase
k59_812589_2	387093.SUN_2266	4.43e-232	654.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,42MV3@68525|delta/epsilon subdivisions,2YNP4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
k59_1396484_1	1537917.JU82_04050	9.15e-108	320.0	COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,42M6S@68525|delta/epsilon subdivisions,2YMJG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
k59_1584245_1	709032.Sulku_0128	1.42e-112	325.0	COG3665@1|root,COG3665@2|Bacteria,1N9DM@1224|Proteobacteria,42QUI@68525|delta/epsilon subdivisions,2YP0W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function (DUF1989)	-	-	-	ko:K09967	-	-	-	-	ko00000	-	-	-	DUF1989
k59_1107045_1	1537917.JU82_10960	2.43e-50	167.0	COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,42MXH@68525|delta/epsilon subdivisions,2YMN3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	4-hydroxybenzoate	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
k59_1107045_2	1249480.B649_01220	7.91e-07	50.1	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,42M7V@68525|delta/epsilon subdivisions,2YMKI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
k59_585589_1	580332.Slit_1031	3.49e-87	263.0	COG0730@1|root,COG0730@2|Bacteria,1MWX2@1224|Proteobacteria,2VMUD@28216|Betaproteobacteria,44VN0@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k59_1339357_1	563040.Saut_2032	1.81e-95	291.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,42N75@68525|delta/epsilon subdivisions,2YNFC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Metallophosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
k59_932853_1	1007105.PT7_1629	2.52e-24	100.0	COG1073@1|root,COG1073@2|Bacteria,1N03B@1224|Proteobacteria,2VV1P@28216|Betaproteobacteria,3T6X2@506|Alcaligenaceae	28216|Betaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4
k59_932853_2	1206777.B195_22175	2.76e-23	92.4	COG4125@1|root,COG4125@2|Bacteria,1RHF1@1224|Proteobacteria,1SD2W@1236|Gammaproteobacteria,1Z8C4@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	S	Chlorhexidine efflux transporter	-	-	-	-	-	-	-	-	-	-	-	-	BTP
k59_1753243_2	709032.Sulku_2315	1.21e-98	294.0	2A4YW@1|root,30TKN@2|Bacteria,1PDH4@1224|Proteobacteria,42SHS@68525|delta/epsilon subdivisions,2YPG5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1289266_1	395963.Bind_0965	2.65e-68	233.0	COG1629@1|root,COG4771@2|Bacteria,1MW7D@1224|Proteobacteria,2TS7D@28211|Alphaproteobacteria,3NC2D@45404|Beijerinckiaceae	28211|Alphaproteobacteria	P	TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_1399428_2	709032.Sulku_0597	2.02e-38	136.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,42MMG@68525|delta/epsilon subdivisions,2YMCT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
k59_1339391_1	1304883.KI912532_gene446	3.01e-113	336.0	COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,2VHI3@28216|Betaproteobacteria,2KV76@206389|Rhodocyclales	206389|Rhodocyclales	I	Long-chain fatty acid transport protein	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k59_1339391_2	1123367.C666_05255	2.07e-26	100.0	COG1607@1|root,COG1607@2|Bacteria,1MZAZ@1224|Proteobacteria,2VR9M@28216|Betaproteobacteria,2KX58@206389|Rhodocyclales	206389|Rhodocyclales	I	Thioesterase superfamily	-	-	-	ko:K10806	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT
k59_1875674_1	709032.Sulku_1448	1.17e-126	372.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,42MIH@68525|delta/epsilon subdivisions,2YRAS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
k59_640504_1	1537917.JU82_07390	2.18e-35	122.0	COG3272@1|root,COG3272@2|Bacteria	2|Bacteria	L	Protein of unknown function (DUF1722)	ybgA	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
k59_640504_2	709032.Sulku_1616	2.1e-38	140.0	COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,42MQ6@68525|delta/epsilon subdivisions,2YNPN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DNA photolyase family	phrB	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
k59_585688_1	90814.KL370892_gene2250	1.08e-24	103.0	COG0755@1|root,COG0755@2|Bacteria,1RG6M@1224|Proteobacteria,1RX07@1236|Gammaproteobacteria,45ZPJ@72273|Thiotrichales	72273|Thiotrichales	O	PFAM Cytochrome c assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
k59_585688_2	870187.Thini_3152	2.28e-25	107.0	COG1333@1|root,COG1333@2|Bacteria,1N6XE@1224|Proteobacteria,1RXXZ@1236|Gammaproteobacteria,46045@72273|Thiotrichales	72273|Thiotrichales	O	Cytochrome c-type biogenesis protein Ccs1 ResB	-	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
k59_101938_1	1120999.JONM01000034_gene3994	1.65e-58	189.0	COG1028@1|root,COG1028@2|Bacteria,1MWZE@1224|Proteobacteria,2VJFB@28216|Betaproteobacteria	28216|Betaproteobacteria	IQ	Short-chain dehydrogenase reductase (SDR)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
k59_458995_1	709032.Sulku_0289	2.52e-97	288.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,42MIF@68525|delta/epsilon subdivisions,2YNW4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
k59_1875708_1	580332.Slit_0906	6.74e-47	155.0	COG3086@1|root,COG3086@2|Bacteria,1NMXY@1224|Proteobacteria,2W88E@28216|Betaproteobacteria,44WJ3@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Positive regulator of sigma(E), RseC/MucC	-	-	-	ko:K03803	-	-	-	-	ko00000,ko03021	-	-	-	RseC_MucC
k59_1875708_2	580332.Slit_0907	2.38e-45	149.0	2DBX8@1|root,2ZBN7@2|Bacteria,1RABM@1224|Proteobacteria,2VQYS@28216|Betaproteobacteria,44WBZ@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function, DUF269	-	-	-	-	-	-	-	-	-	-	-	-	DUF269
k59_1339435_1	159087.Daro_1289	4.51e-89	263.0	COG0221@1|root,COG0221@2|Bacteria,1RA2F@1224|Proteobacteria,2VQC0@28216|Betaproteobacteria,2KW7D@206389|Rhodocyclales	206389|Rhodocyclales	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
k59_1339435_2	1304883.KI912532_gene2960	4.29e-19	83.6	COG3298@1|root,COG3298@2|Bacteria,1MVZJ@1224|Proteobacteria,2VISP@28216|Betaproteobacteria,2KV43@206389|Rhodocyclales	206389|Rhodocyclales	L	3'-5' exonuclease related to the exonuclease domain of PolB	-	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
k59_1242115_1	709032.Sulku_2352	2.27e-102	298.0	COG2952@1|root,COG2952@2|Bacteria,1PBRU@1224|Proteobacteria,42MEP@68525|delta/epsilon subdivisions,2YN8A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09804	-	-	-	-	ko00000	-	-	-	DUF507
k59_300202_1	1537917.JU82_08635	1.94e-97	291.0	COG1578@1|root,COG1578@2|Bacteria,1RI11@1224|Proteobacteria,42RA1@68525|delta/epsilon subdivisions,2YNYT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function DUF89	-	-	-	ko:K09116	-	-	-	-	ko00000	-	-	-	DUF89
k59_1475671_1	1225184.ALXE01000021_gene2640	3.75e-35	133.0	COG2265@1|root,COG2265@2|Bacteria,1N8DN@1224|Proteobacteria,1RMX4@1236|Gammaproteobacteria,3VXW9@53335|Pantoea	1236|Gammaproteobacteria	H	Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA	rlmC	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.189	ko:K03212	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	tRNA_U5-meth_tr
k59_595098_1	709032.Sulku_0879	2.28e-40	135.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,42SEH@68525|delta/epsilon subdivisions,2YPE2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	FG	Hit family	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
k59_595098_2	1537917.JU82_11180	8.73e-87	263.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,42MB0@68525|delta/epsilon subdivisions,2YMC0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
k59_1592998_1	1304883.KI912532_gene3229	2.76e-111	338.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,2VHKD@28216|Betaproteobacteria,2KV11@206389|Rhodocyclales	206389|Rhodocyclales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD-TM1,SecD_SecF,Sec_GG
k59_1592998_2	159087.Daro_3281	3.53e-63	201.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,2VHZG@28216|Betaproteobacteria,2KVVV@206389|Rhodocyclales	206389|Rhodocyclales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k59_710780_2	1249480.B649_08190	5.02e-101	296.0	COG1704@1|root,COG1704@2|Bacteria,1N0DU@1224|Proteobacteria,43B6Y@68525|delta/epsilon subdivisions,2YPB4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
k59_948009_1	1173027.Mic7113_6246	7.1e-37	142.0	COG0642@1|root,COG2203@1|root,COG3829@1|root,COG4191@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1G09B@1117|Cyanobacteria,1H7M6@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,PAS_4
k59_300239_1	709032.Sulku_1449	9.28e-42	139.0	COG0640@1|root,COG0640@2|Bacteria,1Q99U@1224|Proteobacteria,42ZT4@68525|delta/epsilon subdivisions,2YRS2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
k59_1417319_1	709032.Sulku_1588	3.26e-58	187.0	COG1472@1|root,COG1472@2|Bacteria,1QUPT@1224|Proteobacteria,42VS9@68525|delta/epsilon subdivisions,2YQD2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Cytochrome c family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365
k59_1417319_2	1249480.B649_04185	2.34e-23	93.2	2DQ0J@1|root,3348C@2|Bacteria,1NBQ2@1224|Proteobacteria,42UFN@68525|delta/epsilon subdivisions,2YPUT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Chemoreceptor zinc-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CZB
k59_770016_1	709032.Sulku_1604	1.66e-38	137.0	COG1565@1|root,COG1565@2|Bacteria,1QNDB@1224|Proteobacteria,42MQ8@68525|delta/epsilon subdivisions,2YNBU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
k59_770016_3	1249480.B649_04120	4.81e-36	122.0	COG2104@1|root,COG2104@2|Bacteria,1NG8E@1224|Proteobacteria,42WUA@68525|delta/epsilon subdivisions,2YQSD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	thiamine biosynthesis protein ThiS	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
k59_888487_1	509191.AEDB02000023_gene3574	1.96e-43	156.0	COG1106@1|root,COG1106@2|Bacteria,1TSBY@1239|Firmicutes,249DS@186801|Clostridia,3WJY3@541000|Ruminococcaceae	186801|Clostridia	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K06926	-	-	-	-	ko00000	-	-	-	AAA_21
k59_1417320_1	387093.SUN_0215	3.88e-115	333.0	COG0720@1|root,COG0720@2|Bacteria,1R62M@1224|Proteobacteria,42R4Z@68525|delta/epsilon subdivisions,2YNZW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	synthase	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
k59_125978_1	159087.Daro_0886	9.52e-56	184.0	COG2165@1|root,COG2165@2|Bacteria,1RHHG@1224|Proteobacteria,2VT5N@28216|Betaproteobacteria,2KWMN@206389|Rhodocyclales	206389|Rhodocyclales	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K12285	-	-	-	-	ko00000,ko02044	-	-	-	N_methyl
k59_710792_1	709032.Sulku_0435	1.63e-81	254.0	COG0642@1|root,COG2205@2|Bacteria,1QUJ5@1224|Proteobacteria,42NJC@68525|delta/epsilon subdivisions,2YMGQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	cosS	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_300241_1	1537917.JU82_08050	8.73e-208	576.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,42MHR@68525|delta/epsilon subdivisions,2YN1K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_300241_2	563040.Saut_1814	5.43e-54	174.0	2AIG0@1|root,318XK@2|Bacteria,1Q14Q@1224|Proteobacteria,42SW7@68525|delta/epsilon subdivisions,2YPQ3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_300241_3	1537917.JU82_08045	2.72e-30	108.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,42TPU@68525|delta/epsilon subdivisions,2YPES@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the thioredoxin family	trx2	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
k59_182980_1	62928.azo2850	3.12e-38	142.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,2VHKK@28216|Betaproteobacteria,2KW0D@206389|Rhodocyclales	206389|Rhodocyclales	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
k59_1710231_1	1235793.C809_01827	0.000137	50.4	COG0745@1|root,COG0745@2|Bacteria,1TYPK@1239|Firmicutes,247Y9@186801|Clostridia,27JCM@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_1006943_1	1121116.KB894766_gene364	2.45e-25	105.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,2VHJ1@28216|Betaproteobacteria,4AAXV@80864|Comamonadaceae	28216|Betaproteobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
k59_1006943_2	1304883.KI912532_gene1571	2.91e-15	79.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,2VI5Q@28216|Betaproteobacteria,2KUH4@206389|Rhodocyclales	206389|Rhodocyclales	D	Peptidoglycan polymerase that is essential for cell division	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
k59_1357509_1	1454004.AW11_03962	1.56e-36	138.0	COG4928@1|root,COG4928@2|Bacteria,1MWRP@1224|Proteobacteria,2VUGS@28216|Betaproteobacteria,1KQT8@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	KAP family P-loop domain	-	-	-	-	-	-	-	-	-	-	-	-	KAP_NTPase
k59_183003_1	709032.Sulku_0726	7.94e-42	144.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,42MUR@68525|delta/epsilon subdivisions,2YMG3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
k59_183003_2	709032.Sulku_0727	7.51e-55	184.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,42M48@68525|delta/epsilon subdivisions,2YMM2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
k59_770055_1	709032.Sulku_0800	4.41e-110	328.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,42PGM@68525|delta/epsilon subdivisions,2YTQ3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
k59_359436_1	1121035.AUCH01000003_gene1241	9.93e-106	317.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,2VISB@28216|Betaproteobacteria,2KVNS@206389|Rhodocyclales	206389|Rhodocyclales	I	Biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
k59_1357521_1	1442598.JABW01000002_gene1692	1.26e-47	159.0	COG1351@1|root,COG1351@2|Bacteria,1Q73I@1224|Proteobacteria,42S3A@68525|delta/epsilon subdivisions	1224|Proteobacteria	H	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
k59_1006981_1	1165096.ARWF01000001_gene1423	1.49e-08	54.7	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VNYV@28216|Betaproteobacteria,2KMCT@206350|Nitrosomonadales	206350|Nitrosomonadales	T	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_1006981_2	717774.Marme_1026	6.72e-31	118.0	COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,1RNUB@1236|Gammaproteobacteria,1XH2C@135619|Oceanospirillales	135619|Oceanospirillales	M	mechanosensitive ion channel	-	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
k59_1242265_2	98439.AJLL01000097_gene2023	4.38e-29	120.0	COG0642@1|root,COG0745@1|root,COG2114@1|root,COG2203@1|root,COG3437@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3437@2|Bacteria,1G0F6@1117|Cyanobacteria	1117|Cyanobacteria	T	PFAM Adenylate and Guanylate cyclase catalytic domain	cyaC	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	GAF,Guanylate_cyc,HATPase_c,HisKA,Response_reg
k59_478446_1	1249480.B649_00285	3.23e-137	400.0	COG3174@1|root,COG3174@2|Bacteria,1NDBI@1224|Proteobacteria,42QBM@68525|delta/epsilon subdivisions,2YNPT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	MgtC family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
k59_478446_2	90814.KL370891_gene1383	2.3e-64	222.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,4609X@72273|Thiotrichales	72273|Thiotrichales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4
k59_1710297_1	1537917.JU82_04920	1.01e-84	266.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,42M81@68525|delta/epsilon subdivisions,2YMTF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_830482_1	1304883.KI912532_gene179	4.62e-96	303.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,2KU84@206389|Rhodocyclales	206389|Rhodocyclales	T	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,PAS_8
k59_1064388_1	857087.Metme_3422	6.69e-61	198.0	COG0600@1|root,COG0600@2|Bacteria,1MU6Q@1224|Proteobacteria,1RPP1@1236|Gammaproteobacteria,1XE8H@135618|Methylococcales	135618|Methylococcales	P	PFAM Binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K15577	ko00910,ko02010,map00910,map02010	M00438	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16.1,3.A.1.16.2	-	-	BPD_transp_1
k59_1064388_2	1120970.AUBZ01000019_gene3563	1.25e-29	116.0	COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,1RPUP@1236|Gammaproteobacteria,465AR@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components	nrtC	-	-	ko:K15576	ko00910,ko02010,map00910,map02010	M00438	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16.1,3.A.1.16.2	-	-	NMT1_2
k59_478500_1	1123053.AUDG01000017_gene3344	2.88e-75	246.0	COG3540@1|root,COG3540@2|Bacteria,1MWAF@1224|Proteobacteria,1RNY4@1236|Gammaproteobacteria,1X132@135613|Chromatiales	135613|Chromatiales	P	PhoD-like phosphatase, N-terminal domain	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD,PhoD_N
k59_1535600_1	640081.Dsui_0872	5.24e-67	211.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,2VI74@28216|Betaproteobacteria,2KV3I@206389|Rhodocyclales	206389|Rhodocyclales	L	Endonuclease/Exonuclease/phosphatase family	xthA2	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
k59_1064422_1	709032.Sulku_0059	9.82e-87	258.0	COG1714@1|root,COG1714@2|Bacteria,1N2TA@1224|Proteobacteria	1224|Proteobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
k59_1064422_2	1249480.B649_00235	1.34e-153	439.0	COG0477@1|root,COG2814@2|Bacteria,1MVZI@1224|Proteobacteria,42P57@68525|delta/epsilon subdivisions,2YMGG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EGP	Major facilitator superfamily	-	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1_like
k59_183092_1	1304883.KI912532_gene1371	4.56e-117	349.0	COG0840@1|root,COG0840@2|Bacteria,1NJXF@1224|Proteobacteria,2VM8I@28216|Betaproteobacteria,2KUYK@206389|Rhodocyclales	206389|Rhodocyclales	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal
k59_1475874_1	929558.SMGD1_0386	3.65e-106	326.0	COG0840@1|root,COG0840@2|Bacteria,1N5N4@1224|Proteobacteria,42RSG@68525|delta/epsilon subdivisions,2YRU6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
k59_1475875_1	1537917.JU82_06275	8.03e-80	253.0	COG4753@1|root,COG4753@2|Bacteria,1Q8YM@1224|Proteobacteria,42YGW@68525|delta/epsilon subdivisions,2YR37@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_1124347_1	709032.Sulku_0493	2.27e-59	194.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,42PCH@68525|delta/epsilon subdivisions,2YN62@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	3-deoxy-d-manno-octulosonic-acid transferase	kdtA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	iIT341.HP0957	Glycos_transf_N
k59_1242352_1	1123518.ARWI01000001_gene2408	2.86e-84	257.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,1RNH9@1236|Gammaproteobacteria,4600W@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
k59_1769040_1	1097668.BYI23_B004710	3.1e-18	82.8	2DZ82@1|root,32V6V@2|Bacteria,1N3UK@1224|Proteobacteria,2VY68@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_595314_1	317025.Tcr_1957	3.36e-79	263.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,45ZWV@72273|Thiotrichales	72273|Thiotrichales	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_1124354_1	159087.Daro_2998	1.38e-134	390.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,2VJ2E@28216|Betaproteobacteria,2KVBW@206389|Rhodocyclales	206389|Rhodocyclales	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
k59_1124354_2	159087.Daro_2997	1.4e-72	218.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,2VSHX@28216|Betaproteobacteria,2KWAV@206389|Rhodocyclales	206389|Rhodocyclales	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
k59_1242366_1	709032.Sulku_2087	4.47e-104	309.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,42MDM@68525|delta/epsilon subdivisions,2YMIV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k59_1299055_1	1249480.B649_10570	2.44e-54	182.0	COG4968@1|root,COG4968@2|Bacteria,1R1K8@1224|Proteobacteria,43DAN@68525|delta/epsilon subdivisions,2YTHS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
k59_1242369_2	944547.ABLL_0830	6.69e-59	188.0	COG0586@1|root,COG0586@2|Bacteria,1NBBA@1224|Proteobacteria,42MFR@68525|delta/epsilon subdivisions,2YMZ2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	membrane-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
k59_9429_1	159087.Daro_3933	1.97e-67	212.0	COG0204@1|root,COG0204@2|Bacteria,1N2DG@1224|Proteobacteria,2VSJD@28216|Betaproteobacteria,2KW55@206389|Rhodocyclales	206389|Rhodocyclales	I	acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k59_1124382_1	305900.GV64_12460	1.06e-06	50.8	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,1RMEI@1236|Gammaproteobacteria,1XH9W@135619|Oceanospirillales	135619|Oceanospirillales	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
k59_1124382_2	1123517.JOMR01000001_gene1082	6.1e-117	352.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,1RND6@1236|Gammaproteobacteria,45ZVZ@72273|Thiotrichales	72273|Thiotrichales	P	inner membrane component	-	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
k59_1710400_1	273121.WS1709	9.1e-29	106.0	COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,42QW5@68525|delta/epsilon subdivisions,2YNWG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
k59_1710400_2	1408442.JADE01000006_gene288	3.72e-18	77.0	COG0255@1|root,COG0255@2|Bacteria,1Q5ZI@1224|Proteobacteria,42VCR@68525|delta/epsilon subdivisions,2YQ6C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
k59_770189_1	709032.Sulku_1318	7.5e-10	60.1	COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,42R55@68525|delta/epsilon subdivisions,2YNS0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
k59_770189_2	749222.Nitsa_0149	2.7e-57	185.0	COG2078@1|root,COG2078@2|Bacteria,1RJP4@1224|Proteobacteria,42SBG@68525|delta/epsilon subdivisions,2YP68@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM AMMECR1 domain protein	-	-	-	ko:K09141	-	-	-	-	ko00000	-	-	-	AMMECR1
k59_595353_1	1278073.MYSTI_00210	7.29e-18	87.8	COG0457@1|root,COG0741@1|root,COG0457@2|Bacteria,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,42N7A@68525|delta/epsilon subdivisions,2WPM9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	transglycosylase	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16,TPR_6,TPR_8
k59_890744_1	159087.Daro_0507	5.96e-39	133.0	2CJFN@1|root,32ZIB@2|Bacteria,1N7QI@1224|Proteobacteria,2VX2C@28216|Betaproteobacteria,2KX8A@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_890744_2	159087.Daro_0508	8.05e-32	118.0	28P0I@1|root,2ZBX5@2|Bacteria,1RB8U@1224|Proteobacteria,2VQ6K@28216|Betaproteobacteria,2KW9E@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF3025)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3025
k59_832808_1	709032.Sulku_1664	2.26e-81	257.0	COG4753@1|root,COG4753@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	3.1.3.3,4.6.1.1	ko:K01768,ko:K07315	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	Guanylate_cyc,HATPase_c,HisKA,Pkinase,Response_reg,SpoIIE
k59_67510_1	1209072.ALBT01000009_gene3062	4.87e-23	112.0	COG2133@1|root,COG3210@1|root,COG2133@2|Bacteria,COG3210@2|Bacteria,1R4VM@1224|Proteobacteria,1RQVY@1236|Gammaproteobacteria,1FH0J@10|Cellvibrio	1236|Gammaproteobacteria	GU	pyrroloquinoline quinone binding	mshQ	-	-	ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	Bactofilin,Laminin_G_3,PA14
k59_11064_2	1249480.B649_00600	1.67e-101	306.0	COG0642@1|root,COG2205@2|Bacteria,1N9SU@1224|Proteobacteria,43BZY@68525|delta/epsilon subdivisions,2YTEZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c
k59_657676_1	887898.HMPREF0551_0056	1.09e-34	135.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,2VHGF@28216|Betaproteobacteria,1K3BJ@119060|Burkholderiaceae	28216|Betaproteobacteria	GM	Polysaccharide biosynthesis protein CapD	capD	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
k59_1009482_1	709032.Sulku_0381	0.0	1030.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2YMRM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
k59_1009482_2	1537917.JU82_04905	1.33e-33	119.0	COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,42TM2@68525|delta/epsilon subdivisions,2YPMC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
k59_832853_1	709032.Sulku_1266	1.62e-48	166.0	COG1085@1|root,COG1085@2|Bacteria,1MU3E@1224|Proteobacteria,42MP4@68525|delta/epsilon subdivisions,2YNIF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1085 Galactose-1-phosphate uridylyltransferase	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
k59_1478279_1	159087.Daro_3347	7.18e-112	330.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,2WEJI@28216|Betaproteobacteria,2KUP5@206389|Rhodocyclales	206389|Rhodocyclales	P	Ion channel	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_N
k59_1301038_2	1537917.JU82_03800	3.32e-52	179.0	COG2198@1|root,COG2198@2|Bacteria,1PCKH@1224|Proteobacteria,42W9Z@68525|delta/epsilon subdivisions,2YQ6K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1538029_1	1502770.JQMG01000001_gene192	2.31e-31	109.0	2DDM5@1|root,2ZII8@2|Bacteria,1P40F@1224|Proteobacteria,2W552@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_245115_1	387093.SUN_2229	1.06e-163	466.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,42M9G@68525|delta/epsilon subdivisions,2YMSC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
k59_245115_2	1165841.SULAR_07610	9.55e-15	72.0	COG0852@1|root,COG0852@2|Bacteria,1MX4B@1224|Proteobacteria,42NAR@68525|delta/epsilon subdivisions,2YN6R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
k59_1654004_2	580332.Slit_2473	1.61e-74	225.0	COG1765@1|root,COG1765@2|Bacteria,1RCZW@1224|Proteobacteria,2VR62@28216|Betaproteobacteria,44VTK@713636|Nitrosomonadales	28216|Betaproteobacteria	O	OsmC-like protein	yhfA	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
k59_1831743_2	886293.Sinac_3931	5.61e-06	48.1	COG0028@1|root,COG0028@2|Bacteria,2IXMU@203682|Planctomycetes	2|Bacteria	H	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	ilvB2	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_420837_1	1537917.JU82_08735	1.49e-65	209.0	COG3034@1|root,COG3034@2|Bacteria,1N2B6@1224|Proteobacteria,42QS4@68525|delta/epsilon subdivisions,2YNYQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	ErfK YbiS YcfS YnhG family protein	pgp2	-	-	-	-	-	-	-	-	-	-	-	YkuD
k59_420837_2	709032.Sulku_0724	8.78e-164	469.0	COG3608@1|root,COG3608@2|Bacteria,1Q5G3@1224|Proteobacteria,42MSH@68525|delta/epsilon subdivisions,2YMTA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	C-terminal domain of metallo-carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M99,Peptidase_M99_C
k59_540544_1	717773.Thicy_0857	1.37e-108	320.0	COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,1RNMW@1236|Gammaproteobacteria,45ZWH@72273|Thiotrichales	72273|Thiotrichales	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_1726255_2	1249480.B649_04235	2.15e-97	296.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,42MXQ@68525|delta/epsilon subdivisions,2YM9P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0098	PALP,Thr_synth_N
k59_1608638_1	159087.Daro_2180	3.96e-124	365.0	COG3522@1|root,COG3522@2|Bacteria,1MXKE@1224|Proteobacteria,2VHVK@28216|Betaproteobacteria,2KXAP@206389|Rhodocyclales	206389|Rhodocyclales	S	Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE	-	-	-	ko:K11893	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_VasE
k59_1784814_1	929506.CbC4_2372	2.39e-121	359.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia,36F7Z@31979|Clostridiaceae	186801|Clostridia	L	Reverse transcriptase	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1
k59_1437806_2	709032.Sulku_1317	6.32e-42	152.0	COG0835@1|root,COG0835@2|Bacteria,1QVCF@1224|Proteobacteria,42M0F@68525|delta/epsilon subdivisions,2YNAP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	PFAM CheW domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CheW,dCache_1
k59_1608651_1	709032.Sulku_0994	6.55e-43	142.0	COG1558@1|root,COG1558@2|Bacteria,1R09B@1224|Proteobacteria	1224|Proteobacteria	N	Flagellar basal body rod FlgEFG protein C-terminal	-	-	-	ko:K02388	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k59_847390_2	159087.Daro_3057	8.87e-27	104.0	COG0697@1|root,COG0697@2|Bacteria,1MZXM@1224|Proteobacteria,2VK90@28216|Betaproteobacteria,2KW2D@206389|Rhodocyclales	206389|Rhodocyclales	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_1437851_1	1049564.TevJSym_ab00430	1.56e-43	155.0	COG0642@1|root,COG2205@2|Bacteria,1QV1H@1224|Proteobacteria,1T5JC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_722762_1	709032.Sulku_2026	1.87e-114	352.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,42KZI@68525|delta/epsilon subdivisions,2YR60@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Domain of unknown function (DUF3458_C) ARM repeats	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,Peptidase_M1
k59_22627_1	159087.Daro_0824	6.67e-45	147.0	COG3905@1|root,COG3905@2|Bacteria,1N7SQ@1224|Proteobacteria,2VVRJ@28216|Betaproteobacteria,2KZAU@206389|Rhodocyclales	206389|Rhodocyclales	K	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_22627_2	159087.Daro_0823	8.32e-09	52.8	COG3668@1|root,COG3668@2|Bacteria,1N016@1224|Proteobacteria,2VVYK@28216|Betaproteobacteria,2KXJT@206389|Rhodocyclales	206389|Rhodocyclales	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
k59_496638_1	267608.RSp1160	2.88e-17	81.3	COG3678@1|root,COG3678@2|Bacteria,1N6PJ@1224|Proteobacteria,2VW8V@28216|Betaproteobacteria,1K7WA@119060|Burkholderiaceae	28216|Betaproteobacteria	NPTU	Heavy-metal resistance	-	-	-	-	-	-	-	-	-	-	-	-	LTXXQ,Metal_resist
k59_613526_1	760154.Sulba_0785	1.08e-68	226.0	COG0840@1|root,COG0840@2|Bacteria,1R9QI@1224|Proteobacteria,42P3E@68525|delta/epsilon subdivisions,2YMG0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Methyl-accepting chemotaxis protein (MCP) signaling domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
k59_145157_2	1304883.KI912532_gene1878	1.16e-73	225.0	COG1418@1|root,COG1418@2|Bacteria,1RB2W@1224|Proteobacteria,2VMZ0@28216|Betaproteobacteria,2KXBW@206389|Rhodocyclales	206389|Rhodocyclales	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
k59_374120_1	1249480.B649_00650	2.43e-91	283.0	COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,42MX8@68525|delta/epsilon subdivisions,2YN00@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	flaB	GO:0001539,GO:0005575,GO:0005576,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_IN,Flagellin_N
k59_1437937_1	1249480.B649_01515	2.62e-107	331.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,42N34@68525|delta/epsilon subdivisions,2YMFS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_C
k59_965707_1	497321.C664_14564	2.11e-82	266.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,2VJ54@28216|Betaproteobacteria,2KV7W@206389|Rhodocyclales	206389|Rhodocyclales	O	Belongs to the peptidase S16 family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
k59_259046_2	94122.Shewana3_1792	9.72e-09	59.3	COG1669@1|root,COG2445@1|root,COG1669@2|Bacteria,COG2445@2|Bacteria,1RJB6@1224|Proteobacteria,1S7H3@1236|Gammaproteobacteria,2QDKT@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
k59_787517_1	595494.Tola_0216	0.000127	45.4	COG3322@1|root,COG5001@1|root,COG3322@2|Bacteria,COG5001@2|Bacteria,1R8U0@1224|Proteobacteria,1RSBQ@1236|Gammaproteobacteria,1Y58S@135624|Aeromonadales	135624|Aeromonadales	T	CHASE4 domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,EAL,GGDEF
k59_787517_2	159087.Daro_0688	4.96e-62	201.0	COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,2VIPV@28216|Betaproteobacteria,2KZEB@206389|Rhodocyclales	206389|Rhodocyclales	P	) H( ) antiporter that extrudes sodium in exchange for external protons	-	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
k59_1143329_1	555778.Hneap_0177	2.63e-14	72.8	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,1RMKQ@1236|Gammaproteobacteria,1WXCF@135613|Chromatiales	135613|Chromatiales	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	-	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
k59_145204_1	1537917.JU82_02150	7.98e-192	538.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,42M9E@68525|delta/epsilon subdivisions,2YMCM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
k59_1028973_1	159087.Daro_3628	6.91e-94	284.0	COG0158@1|root,COG0158@2|Bacteria,1MW0E@1224|Proteobacteria,2VIJT@28216|Betaproteobacteria,2KVF4@206389|Rhodocyclales	206389|Rhodocyclales	G	Fructose-1-6-bisphosphatase, N-terminal domain	-	-	3.1.3.11,3.1.3.37	ko:K01086,ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R01845,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
k59_965756_2	159087.Daro_1465	8.04e-86	257.0	COG3346@1|root,COG3346@2|Bacteria,1MZUH@1224|Proteobacteria,2VSAZ@28216|Betaproteobacteria,2KWKA@206389|Rhodocyclales	206389|Rhodocyclales	S	SURF1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	SURF1
k59_1555577_1	1249480.B649_08165	8.38e-188	546.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,42MKB@68525|delta/epsilon subdivisions,2YMIZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
k59_1849171_1	549.BW31_03626	9.73e-22	97.4	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,3VZIW@53335|Pantoea	1236|Gammaproteobacteria	NT	chemotaxis	tsr	-	-	ko:K03406,ko:K05874,ko:K05875,ko:K05876	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,TarH
k59_1849171_2	1430440.MGMSRv2_3834	1.67e-08	55.5	COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,2TRPX@28211|Alphaproteobacteria,2JPKV@204441|Rhodospirillales	204441|Rhodospirillales	P	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
k59_965784_1	709032.Sulku_2532	2.21e-31	119.0	COG2855@1|root,COG2855@2|Bacteria,1MVIP@1224|Proteobacteria,42P59@68525|delta/epsilon subdivisions,2YMPJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the UPF0324 family	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
k59_1726450_1	1198114.AciX9_2386	1.43e-16	80.9	COG0322@1|root,COG0322@2|Bacteria,3Y2Y7@57723|Acidobacteria,2JI6E@204432|Acidobacteriia	204432|Acidobacteriia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
k59_1726450_2	1122951.ATUE01000007_gene614	4.88e-22	96.3	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,1RNGV@1236|Gammaproteobacteria,3NIZV@468|Moraxellaceae	1236|Gammaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009628,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH,HHH_2,HHH_5,UVR,UvrC_HhH_N
k59_558472_1	159087.Daro_2399	1.36e-55	182.0	COG0489@1|root,COG0489@2|Bacteria,1MVI9@1224|Proteobacteria,2VJEB@28216|Betaproteobacteria,2KUMI@206389|Rhodocyclales	206389|Rhodocyclales	D	COG0489 ATPases involved in chromosome partitioning	-	-	2.7.10.1	ko:K08252	-	-	-	-	ko00000,ko01000	-	-	-	AAA_31
k59_1374661_1	1005058.UMN179_00544	2.76e-105	318.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,1RMU9@1236|Gammaproteobacteria,1Y7IZ@135625|Pasteurellales	135625|Pasteurellales	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
k59_199860_1	159087.Daro_0003	2.32e-105	327.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,2VI8N@28216|Betaproteobacteria,2KUE2@206389|Rhodocyclales	206389|Rhodocyclales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_1849221_1	1165841.SULAR_06763	5.52e-52	166.0	COG0858@1|root,COG0858@2|Bacteria,1Q48R@1224|Proteobacteria,42UQE@68525|delta/epsilon subdivisions,2YPZY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
k59_1849221_2	1165841.SULAR_06768	3.03e-51	179.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,42M5Q@68525|delta/epsilon subdivisions,2YM9V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
k59_1143439_1	709032.Sulku_1936	2.61e-102	305.0	COG0147@1|root,COG0147@2|Bacteria,1R5Y8@1224|Proteobacteria,42P2B@68525|delta/epsilon subdivisions,2YMFR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EH	component I	pabB	-	2.6.1.85	ko:K01665	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	Chorismate_bind
k59_675479_1	159087.Daro_3741	3.3e-87	259.0	COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,2VSP2@28216|Betaproteobacteria,2KW78@206389|Rhodocyclales	206389|Rhodocyclales	I	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	pgpA	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
k59_675479_2	1123487.KB892834_gene2605	8.77e-18	77.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,2VUBZ@28216|Betaproteobacteria,2KWWM@206389|Rhodocyclales	206389|Rhodocyclales	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
k59_313980_1	709032.Sulku_0674	1e-154	440.0	COG1466@1|root,COG1466@2|Bacteria,1RHE9@1224|Proteobacteria,42RI9@68525|delta/epsilon subdivisions,2YP40@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA polymerase III	-	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
k59_787657_1	709032.Sulku_1606	1.54e-25	103.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,42MYN@68525|delta/epsilon subdivisions,2YMXA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	molybdopterin oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin,Molydop_binding
k59_787657_2	709032.Sulku_1607	4.82e-60	192.0	COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1RD7I@1224|Proteobacteria,42SM8@68525|delta/epsilon subdivisions,2YPEY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Response regulator receiver	-	-	-	ko:K03415	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CheW,Response_reg
k59_496837_2	1537917.JU82_05750	1.44e-205	574.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,42MWJ@68525|delta/epsilon subdivisions,2YM9G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
k59_787670_1	709032.Sulku_0801	4.84e-40	137.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	ohrR	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
k59_787670_2	1249480.B649_08100	4.08e-13	69.7	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,42PGM@68525|delta/epsilon subdivisions,2YTQ3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
k59_199921_1	1537917.JU82_08620	2.16e-90	286.0	COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,42M8J@68525|delta/epsilon subdivisions,2YNGB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member	recD	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2,Viral_helicase1
k59_145319_1	1304883.KI912532_gene3092	9.43e-129	391.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,2VH5Z@28216|Betaproteobacteria,2KVPX@206389|Rhodocyclales	206389|Rhodocyclales	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k59_613763_1	387093.SUN_1043	2.78e-96	289.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,42MZR@68525|delta/epsilon subdivisions,2YN0Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
k59_1726513_1	159087.Daro_0112	2.03e-156	446.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,2VH8Q@28216|Betaproteobacteria,2KURV@206389|Rhodocyclales	206389|Rhodocyclales	M	Peptidoglycan polymerase that is essential for cell wall elongation	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
k59_374293_1	292415.Tbd_2613	2.62e-34	127.0	COG0730@1|root,COG0730@2|Bacteria	2|Bacteria	S	response to heat	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE,Usp
k59_374293_3	631362.Thi970DRAFT_01625	1.26e-13	70.5	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,1WXY0@135613|Chromatiales	135613|Chromatiales	P	Sulfate transporter antisigma-factor antagonist STAS	-	-	-	-	-	-	-	-	-	-	-	-	STAS,Sulfate_transp
k59_1197735_1	159087.Daro_1427	3.19e-109	330.0	COG0804@1|root,COG0804@2|Bacteria,1MU5P@1224|Proteobacteria,2VJYX@28216|Betaproteobacteria,2KUE8@206389|Rhodocyclales	206389|Rhodocyclales	E	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family	ureC	-	3.5.1.5	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Urease_alpha
k59_1608905_2	1123034.JMKP01000008_gene486	2.31e-14	72.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,1RNZZ@1236|Gammaproteobacteria,3NJMQ@468|Moraxellaceae	1236|Gammaproteobacteria	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	iECSF_1327.ECSF_2340	AIRS,AIRS_C
k59_315736_1	1249480.B649_08265	6.73e-73	232.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2YMQG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
k59_1787295_1	709032.Sulku_0129	3.43e-126	392.0	COG0439@1|root,COG1984@1|root,COG2049@1|root,COG0439@2|Bacteria,COG1984@2|Bacteria,COG2049@2|Bacteria,1MU4H@1224|Proteobacteria,42P49@68525|delta/epsilon subdivisions,2YNRZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EI	Allophanate hydrolase subunit 1	-	-	6.3.4.6	ko:K01941	ko00220,ko00791,ko01100,map00220,map00791,map01100	-	R00774	RC00378	ko00000,ko00001,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,CT_A_B,CT_C_D
k59_1084743_1	1132855.KB913035_gene245	1.21e-56	195.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,2VINT@28216|Betaproteobacteria,2KKNP@206350|Nitrosomonadales	206350|Nitrosomonadales	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C
k59_1084743_2	666681.M301_2772	6.48e-28	111.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,2VHT1@28216|Betaproteobacteria,2KM4P@206350|Nitrosomonadales	206350|Nitrosomonadales	J	TIGRFAM arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
k59_1032502_1	1537917.JU82_11165	1.36e-35	128.0	COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,42MJK@68525|delta/epsilon subdivisions,2YMV3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0400	LYTB
k59_202986_1	1249480.B649_08015	1.72e-96	287.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,42MV7@68525|delta/epsilon subdivisions,2YMFH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
k59_1084746_1	944546.ABED_2063	2.8e-10	66.6	COG2604@1|root,COG2604@2|Bacteria,1Q4PY@1224|Proteobacteria,42X2A@68525|delta/epsilon subdivisions,2YTNQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function DUF115	-	-	-	-	-	-	-	-	-	-	-	-	MAF_flag10
k59_1852324_1	1537917.JU82_01665	6.42e-183	550.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2YMP9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5,RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_617099_1	159087.Daro_0552	5.61e-24	98.2	COG0583@1|root,COG0583@2|Bacteria,1MZTA@1224|Proteobacteria,2VJTZ@28216|Betaproteobacteria,2KW57@206389|Rhodocyclales	206389|Rhodocyclales	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_617099_2	159087.Daro_0553	2.88e-56	180.0	COG1741@1|root,COG1741@2|Bacteria,1MVSW@1224|Proteobacteria,2VHPA@28216|Betaproteobacteria,2KW94@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
k59_1670643_1	1042377.AFPJ01000042_gene1076	1.24e-39	151.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,1RNW3@1236|Gammaproteobacteria,464F1@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0000018,GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008301,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030554,GO:0030983,GO:0031323,GO:0032136,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	iECW_1372.ECW_m2935,iWFL_1372.ECW_m2935	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
k59_561694_1	1047013.AQSP01000089_gene1181	2.01e-45	167.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	cyaJ	-	4.6.1.1	ko:K01768,ko:K02483	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	Guanylate_cyc,HTH_18,TPR_16,TPR_19,TPR_2,TPR_8
k59_1377052_2	1537917.JU82_07000	4.93e-86	270.0	COG1766@1|root,COG1766@2|Bacteria,1MUQR@1224|Proteobacteria,42N04@68525|delta/epsilon subdivisions,2YMF6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	The M ring may be actively involved in energy transduction	fliF	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
k59_849428_1	404380.Gbem_1615	1.24e-121	367.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,42MEI@68525|delta/epsilon subdivisions,2WJEG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_1314497_1	1279009.ADICEAN_03943	4.5e-15	80.5	COG1572@1|root,COG3121@1|root,COG3291@1|root,COG1572@2|Bacteria,COG3121@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.4.24.3	ko:K01387,ko:K07346	-	-	-	-	ko00000,ko01000,ko01002,ko02035,ko02042,ko02044,ko03110	-	-	-	ASH,Alpha_L_fucos,CHU_C,Calx-beta,DUF4091,F5_F8_type_C,G5,PKD,PPC,Peptidase_M9,Peptidase_M9_N,Trypsin_2,YSIRK_signal
k59_1314500_1	1249480.B649_08070	8.82e-87	278.0	COG5001@1|root,COG5001@2|Bacteria,1R4H0@1224|Proteobacteria	1224|Proteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_81549_1	709032.Sulku_2023	6.41e-52	166.0	COG4654@1|root,COG4654@2|Bacteria,1R1K5@1224|Proteobacteria,42WVZ@68525|delta/epsilon subdivisions,2YQRY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
k59_81549_2	1249480.B649_09460	2.01e-76	251.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,42KZI@68525|delta/epsilon subdivisions,2YR60@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Domain of unknown function (DUF3458_C) ARM repeats	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,Peptidase_M1
k59_1611253_1	709032.Sulku_0709	1.83e-40	138.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,42T4I@68525|delta/epsilon subdivisions,2YPMM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the UPF0312 family	Cj0420	-	-	-	-	-	-	-	-	-	-	-	YceI
k59_1611253_2	709032.Sulku_0708	2.85e-18	80.5	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,42N5N@68525|delta/epsilon subdivisions,2YMVJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
k59_1314530_1	1165841.SULAR_07770	4.34e-125	373.0	COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,42P71@68525|delta/epsilon subdivisions,2YNAA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Phospholipid glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5,Acyltransferase
k59_906953_1	596153.Alide_0761	1.7e-70	235.0	COG2931@1|root,COG2931@2|Bacteria,1N1NQ@1224|Proteobacteria,2WHZF@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1611259_1	384676.PSEEN1497	1.27e-13	73.6	COG2244@1|root,COG2244@2|Bacteria,1R6ME@1224|Proteobacteria,1SGR4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
k59_1611259_2	999541.bgla_1g20330	3.93e-15	75.9	COG0438@1|root,COG0438@2|Bacteria,1MVA7@1224|Proteobacteria,2VM0Z@28216|Betaproteobacteria,1K0MP@119060|Burkholderiaceae	28216|Betaproteobacteria	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_1146660_1	709032.Sulku_0525	4.29e-57	184.0	COG0745@1|root,COG0745@2|Bacteria,1R9AZ@1224|Proteobacteria,42NYS@68525|delta/epsilon subdivisions,2YNW2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	response regulator	dccR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_500077_1	1249480.B649_10290	1.32e-129	377.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42MNF@68525|delta/epsilon subdivisions,2YMW2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_678650_1	1537917.JU82_08385	2.48e-39	136.0	COG0745@1|root,COG0745@2|Bacteria,1N7TJ@1224|Proteobacteria,42SSI@68525|delta/epsilon subdivisions,2YPE6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_500087_1	159087.Daro_0825	5.55e-45	155.0	COG2223@1|root,COG2223@2|Bacteria,1MU27@1224|Proteobacteria,2VI6Q@28216|Betaproteobacteria,2KUW4@206389|Rhodocyclales	206389|Rhodocyclales	P	MFS/sugar transport protein	narK	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1
k59_500087_2	159087.Daro_0817	1.06e-44	145.0	COG2146@1|root,COG2146@2|Bacteria,1N03R@1224|Proteobacteria,2VSP4@28216|Betaproteobacteria,2KX2K@206389|Rhodocyclales	206389|Rhodocyclales	P	Rieske-like [2Fe-2S] domain	-	-	1.7.1.15	ko:K00363	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,Rieske_2
k59_332740_2	1249480.B649_06880	9.9e-09	56.2	COG2309@1|root,COG2309@2|Bacteria,1R4I5@1224|Proteobacteria	1224|Proteobacteria	E	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1804742_1	1046724.KB889955_gene2500	3.75e-27	120.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,466AG@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,PAS,PAS_3,PAS_4,PAS_8,PAS_9
k59_165776_1	1249480.B649_03270	7.84e-103	315.0	COG2199@1|root,COG3706@2|Bacteria,1NECV@1224|Proteobacteria,42PZK@68525|delta/epsilon subdivisions,2YT9R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_927224_1	395494.Galf_1098	6.9e-115	339.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	4.1.99.22	ko:K03639,ko:K15045	ko00790,ko01100,ko04122,ko05164,map00790,map01100,map04122,map05164	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
k59_1871187_2	1458863.A0A088C4Z8_9CAUD	1.07e-19	82.8	4QDFX@10239|Viruses,4QYNB@35237|dsDNA viruses  no RNA stage,4QU7E@28883|Caudovirales,4QJCR@10662|Myoviridae	10662|Myoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_278848_1	1165841.SULAR_06893	1.14e-32	118.0	2BTJ1@1|root,32NRK@2|Bacteria,1Q3XC@1224|Proteobacteria,42RS4@68525|delta/epsilon subdivisions,2YPVI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Lipopolysaccharide-assembly	-	-	-	-	-	-	-	-	-	-	-	-	LptE
k59_278848_2	1165841.SULAR_06898	3.98e-63	213.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,42MRQ@68525|delta/epsilon subdivisions,2YMJY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1g
k59_455110_1	1457393.AZ09_07330	1.13e-90	293.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,2TR4E@28211|Alphaproteobacteria,2JQC9@204441|Rhodospirillales	204441|Rhodospirillales	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_1804751_1	349124.Hhal_1682	4.14e-141	415.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,1RMT8@1236|Gammaproteobacteria,1WXCW@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
k59_1749614_1	387093.SUN_1583	4.82e-118	343.0	COG0177@1|root,COG0177@2|Bacteria,1RAK3@1224|Proteobacteria,42M4V@68525|delta/epsilon subdivisions,2YNKT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	tigr02757	-	-	-	-	-	-	-	-	-	-	-	-	DUF2400
k59_1580075_1	159087.Daro_0933	2.05e-58	186.0	COG2119@1|root,COG2119@2|Bacteria,1RDDV@1224|Proteobacteria,2VQ6X@28216|Betaproteobacteria	28216|Betaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
k59_1580075_2	159087.Daro_0934	5.57e-63	195.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,2VR52@28216|Betaproteobacteria,2KWB1@206389|Rhodocyclales	206389|Rhodocyclales	K	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
k59_1461220_1	929558.SMGD1_1598	1.37e-56	191.0	COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,42PIT@68525|delta/epsilon subdivisions,2YTJQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
k59_991313_2	1217718.ALOU01000078_gene3495	2.09e-101	304.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,2VH4G@28216|Betaproteobacteria,1K00C@119060|Burkholderiaceae	28216|Betaproteobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
k59_1804778_1	326298.Suden_0772	2.19e-14	68.2	COG2608@1|root,COG2608@2|Bacteria,1N81B@1224|Proteobacteria,42VKI@68525|delta/epsilon subdivisions,2YQD5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Heavy-metal-associated domain	-	-	-	-	-	-	-	-	-	-	-	-	HMA
k59_1804778_2	387093.SUN_0578	5.12e-40	134.0	COG1146@1|root,COG1146@2|Bacteria,1NJJD@1224|Proteobacteria,42TVE@68525|delta/epsilon subdivisions,2YPUN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	2-oxoglutarate acceptor oxidoreductase	oorD	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Fer4_6,Fer4_7
k59_865409_1	1249480.B649_00725	7.2e-126	363.0	COG1639@1|root,COG1639@2|Bacteria,1RAH3@1224|Proteobacteria,42PRF@68525|delta/epsilon subdivisions,2YMRX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Signal transduction protein	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_1285149_1	755732.Fluta_0940	3.19e-23	99.8	COG0415@1|root,COG0415@2|Bacteria,4NEDW@976|Bacteroidetes,1HXRR@117743|Flavobacteriia,2PABB@246874|Cryomorphaceae	976|Bacteroidetes	L	PFAM FAD binding domain of DNA photolyase	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
k59_1285149_2	572477.Alvin_0413	1.57e-15	72.0	COG0851@1|root,COG0851@2|Bacteria,1N6QD@1224|Proteobacteria,1SC8W@1236|Gammaproteobacteria,1WZ7H@135613|Chromatiales	135613|Chromatiales	D	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell	minE	-	-	ko:K03608	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinE
k59_1166220_1	159087.Daro_3753	1.46e-70	214.0	COG3766@1|root,COG3766@2|Bacteria,1N14W@1224|Proteobacteria,2VUJZ@28216|Betaproteobacteria,2KZND@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of Unknown Function (DUF350)	-	-	-	ko:K08989	-	-	-	-	ko00000	-	-	-	DUF350
k59_1166220_2	1304883.KI912532_gene1221	6.18e-31	116.0	COG4260@1|root,COG4260@2|Bacteria,1MXTD@1224|Proteobacteria,2VJ2P@28216|Betaproteobacteria,2KVXV@206389|Rhodocyclales	206389|Rhodocyclales	S	Short C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,SHOCT
k59_991361_1	1304883.KI912532_gene407	3.97e-08	52.0	COG2062@1|root,COG2062@2|Bacteria,1RIVH@1224|Proteobacteria,2VSSQ@28216|Betaproteobacteria,2KWCC@206389|Rhodocyclales	206389|Rhodocyclales	T	phosphohistidine phosphatase, SixA	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
k59_991361_2	223283.PSPTO_1515	1.13e-65	208.0	COG0742@1|root,COG0742@2|Bacteria,1MX8Z@1224|Proteobacteria,1RMIB@1236|Gammaproteobacteria,1Z5HI@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	J	Specifically methylates the guanosine in position 1516 of 16S rRNA	rsmJ	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036308,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.242	ko:K15984	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SAM_MT
k59_1053226_1	1537917.JU82_06980	1.27e-111	330.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,42KZH@68525|delta/epsilon subdivisions,2YMZM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
k59_1804826_1	1165841.SULAR_06823	7.51e-124	357.0	COG0745@1|root,COG0745@2|Bacteria,1N7TJ@1224|Proteobacteria,42MTC@68525|delta/epsilon subdivisions,2YMSX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	cosR	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_1285197_2	1537917.JU82_07005	5.62e-214	594.0	COG1536@1|root,COG1536@2|Bacteria,1MV9X@1224|Proteobacteria,42MS3@68525|delta/epsilon subdivisions,2YM90@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar motor switch protein	fliG	GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
k59_1285197_3	709032.Sulku_1916	8.19e-113	331.0	COG1317@1|root,COG1317@2|Bacteria,1NJAJ@1224|Proteobacteria,42P5I@68525|delta/epsilon subdivisions,2YQ57@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar assembly protein FliH	fliH	-	-	ko:K02411	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliH
k59_1395613_1	395494.Galf_0206	4.42e-35	128.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,2VHDR@28216|Betaproteobacteria,44VK7@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
k59_740388_1	1123326.JFBL01000013_gene378	2.34e-107	330.0	COG2604@1|root,COG2604@2|Bacteria,1R4P0@1224|Proteobacteria,42NB8@68525|delta/epsilon subdivisions,2YMMI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	hmm pf01973	pseE	-	-	-	-	-	-	-	-	-	-	-	MAF_flag10
k59_811590_1	436114.SYO3AOP1_1613	1.09e-28	116.0	COG0845@1|root,COG0845@2|Bacteria,2G4EM@200783|Aquificae	200783|Aquificae	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
k59_1512559_1	935836.JAEL01000019_gene886	4.63e-50	174.0	COG0726@1|root,COG0726@2|Bacteria,1V4PK@1239|Firmicutes,4HIZ2@91061|Bacilli,1ZRFH@1386|Bacillus	91061|Bacilli	G	Domain of unknown function (DUF4309)	pgdA	GO:0005575,GO:0016020	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	DUF4309,Polysacc_deac_1
k59_699660_1	1249480.B649_04480	1.88e-95	291.0	COG4191@1|root,COG4191@2|Bacteria,1Q4FH@1224|Proteobacteria,42Z34@68525|delta/epsilon subdivisions,2YRGT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
k59_1461305_1	1249480.B649_01640	1.47e-258	716.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,42N6C@68525|delta/epsilon subdivisions,2YMY6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
k59_1871315_1	1249480.B649_10585	3.3e-102	310.0	COG4972@1|root,COG4972@2|Bacteria,1PZTK@1224|Proteobacteria,42R44@68525|delta/epsilon subdivisions,2YP2H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Pilus assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_740398_1	1485544.JQKP01000001_gene1203	2.06e-62	197.0	COG3637@1|root,COG3637@2|Bacteria,1NIE3@1224|Proteobacteria,2VXMU@28216|Betaproteobacteria,44WMS@713636|Nitrosomonadales	28216|Betaproteobacteria	M	OmpA-like transmembrane domain	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA_membrane
k59_279004_1	1424334.W822_15810	1.2e-97	300.0	COG0477@1|root,COG0477@2|Bacteria,1MXZ3@1224|Proteobacteria,2VH3E@28216|Betaproteobacteria,3T1HK@506|Alcaligenaceae	28216|Betaproteobacteria	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
k59_1219384_1	1537917.JU82_04065	1.04e-49	164.0	COG1040@1|root,COG1040@2|Bacteria,1Q1C2@1224|Proteobacteria,42T93@68525|delta/epsilon subdivisions,2YPEB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	transformation system protein	ctsW	-	-	ko:K02242	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	Pribosyltran
k59_699687_2	395494.Galf_2091	1.27e-41	146.0	COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,2VHHC@28216|Betaproteobacteria,44V22@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004764,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0055114,GO:0061458,GO:0071704,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
k59_636543_1	572480.Arnit_1440	1.5e-55	176.0	COG2010@1|root,COG2010@2|Bacteria,1NKKK@1224|Proteobacteria,42UAC@68525|delta/epsilon subdivisions,2YRSI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
k59_636543_2	1537917.JU82_00575	1.42e-117	349.0	COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,42M8Q@68525|delta/epsilon subdivisions,2YMSH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome c oxidase accessory protein	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
k59_927434_2	1249480.B649_07285	1.57e-93	288.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,42M81@68525|delta/epsilon subdivisions,2YMTF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_279037_1	1304883.KI912532_gene2032	5.79e-107	314.0	COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,2VKE2@28216|Betaproteobacteria,2KVZC@206389|Rhodocyclales	206389|Rhodocyclales	C	NiFe/NiFeSe hydrogenase small subunit C-terminal	-	-	1.12.99.6	ko:K06282	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6
k59_279037_2	159087.Daro_2889	7.53e-39	140.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,2VKZS@28216|Betaproteobacteria,2KUS6@206389|Rhodocyclales	206389|Rhodocyclales	C	Nickel-dependent hydrogenase	-	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
k59_927442_1	1304883.KI912532_gene297	5.72e-146	422.0	COG2358@1|root,COG2358@2|Bacteria,1PNJV@1224|Proteobacteria,2VI8H@28216|Betaproteobacteria,2KVEI@206389|Rhodocyclales	206389|Rhodocyclales	S	NMT1-like family	-	-	-	-	-	-	-	-	-	-	-	-	NMT1_3
k59_1688478_1	1249480.B649_05055	7.77e-50	169.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,42MNB@68525|delta/epsilon subdivisions,2YMKW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
k59_1688478_2	1201288.M900_2243	1.2e-14	76.3	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42P9M@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	chemotaxis	trg_2	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CZB,MCPsignal,dCache_3
k59_636559_1	1537917.JU82_05210	3.34e-112	325.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,42M8A@68525|delta/epsilon subdivisions,2YN5T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the SAICAR synthetase family	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
k59_165962_1	62928.azo2254	3.44e-58	198.0	COG3203@1|root,COG3203@2|Bacteria,1MXEB@1224|Proteobacteria,2VPRW@28216|Betaproteobacteria,2KY1Z@206389|Rhodocyclales	206389|Rhodocyclales	M	Protein of unknown function (DUF1302)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1302
k59_1461352_2	1158338.JNLJ01000001_gene948	2.96e-67	213.0	COG3005@1|root,COG3005@2|Bacteria,2G4ZS@200783|Aquificae	200783|Aquificae	C	NapC/NirT cytochrome c family, N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT
k59_165963_1	443143.GM18_2110	4.77e-54	187.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42MI5@68525|delta/epsilon subdivisions,2WITQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	3-hydroxyacyl-CoA dehydrogenase	-	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1,ECH_2
k59_165963_2	1232410.KI421417_gene2724	2.55e-28	110.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42M0D@68525|delta/epsilon subdivisions,2WK8T@28221|Deltaproteobacteria,43TNY@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Thiolase, C-terminal domain	-	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
k59_43437_1	159087.Daro_3798	2.27e-158	459.0	COG1719@1|root,COG3829@1|root,COG1719@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,2VIKD@28216|Betaproteobacteria,2KUEW@206389|Rhodocyclales	206389|Rhodocyclales	K	Fis family transcriptional regulator	poxR	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat,V4R,XylR_N
k59_1806522_1	709032.Sulku_0842	1.69e-46	164.0	COG1538@1|root,COG1538@2|Bacteria,1QNYC@1224|Proteobacteria,42TDW@68525|delta/epsilon subdivisions,2YPR5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_701363_1	709032.Sulku_1771	9.46e-65	211.0	COG1538@1|root,COG1538@2|Bacteria,1Q1P6@1224|Proteobacteria,42U3E@68525|delta/epsilon subdivisions,2YPSR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_1463056_1	745411.B3C1_12904	3.42e-57	187.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,1RMAE@1236|Gammaproteobacteria,1J5FQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008690,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019294,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046394,GO:0046400,GO:0046401,GO:0046872,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iAF1260.b0918,iB21_1397.B21_00929,iBWG_1329.BWG_0770,iECBD_1354.ECBD_2677,iECB_1328.ECB_00922,iECDH10B_1368.ECDH10B_0988,iECDH1ME8569_1439.ECDH1ME8569_0869,iECD_1391.ECD_00922,iETEC_1333.ETEC_0986,iEcDH1_1363.EcDH1_2725,iEcHS_1320.EcHS_A1025,iEcolC_1368.EcolC_2678,iJO1366.b0918,iJR904.b0918,iPC815.YPO1400,iUMNK88_1353.UMNK88_1071,iY75_1357.Y75_RS04770	CTP_transf_3
k59_742197_1	1121035.AUCH01000006_gene731	3.07e-37	131.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,2VHIC@28216|Betaproteobacteria,2KUY5@206389|Rhodocyclales	206389|Rhodocyclales	E	ABC-type polar amino acid transport system, ATPase component	-	-	-	ko:K10004	ko02010,ko02020,map02010,map02020	M00230	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3.19,3.A.1.3.4	-	-	ABC_tran
k59_742197_2	85643.Tmz1t_1333	5.11e-119	352.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,2VIZ7@28216|Betaproteobacteria,2KUWM@206389|Rhodocyclales	206389|Rhodocyclales	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
k59_1220887_1	452662.SJA_C1-11990	2.34e-66	214.0	2DB9W@1|root,2Z7Z9@2|Bacteria,1MZFV@1224|Proteobacteria,2TU3Q@28211|Alphaproteobacteria,2K8Z9@204457|Sphingomonadales	204457|Sphingomonadales	C	Methane/Phenol/Toluene Hydroxylase	-	-	-	ko:K16243	ko00361,ko00362,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00623,map01100,map01120,map01220	M00548	R03560,R03608,R10042,R10043	RC00046,RC00490	ko00000,ko00001,ko00002	-	-	-	Phenol_Hydrox
k59_1806558_1	1304883.KI912532_gene1807	8.77e-126	377.0	COG3284@1|root,COG3284@2|Bacteria,1NRG5@1224|Proteobacteria,2VICI@28216|Betaproteobacteria,2KV0U@206389|Rhodocyclales	206389|Rhodocyclales	K	Transcriptional activator of acetoin glycerol metabolism	-	-	-	ko:K21405	-	-	-	-	ko00000,ko03000	-	-	-	GAF,HTH_8,Sigma54_activat
k59_1397363_1	1249480.B649_11130	1.35e-199	561.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,42M5M@68525|delta/epsilon subdivisions,2YMGW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	iIT341.HP0144	COX1
k59_1751315_1	324602.Caur_2550	0.000108	48.5	COG3391@1|root,COG4745@1|root,COG3391@2|Bacteria,COG4745@2|Bacteria,2G5PE@200795|Chloroflexi,3757B@32061|Chloroflexia	32061|Chloroflexia	O	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL,PMT_2
k59_742235_1	159087.Daro_3004	5.24e-65	205.0	COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,2VINY@28216|Betaproteobacteria,2KVI6@206389|Rhodocyclales	206389|Rhodocyclales	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
k59_742235_2	159087.Daro_3005	1.27e-23	97.4	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,2VH1F@28216|Betaproteobacteria,2KUMQ@206389|Rhodocyclales	206389|Rhodocyclales	T	response regulator	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
k59_1055312_1	1537917.JU82_05105	7.91e-263	758.0	COG3164@1|root,COG3164@2|Bacteria,1QUYX@1224|Proteobacteria,43CES@68525|delta/epsilon subdivisions,2YTC9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
k59_813599_1	1004149.AFOE01000025_gene3218	1.08e-95	295.0	COG1190@1|root,COG1190@2|Bacteria,4NDZN@976|Bacteroidetes,1HXY4@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DUF4332,tRNA-synt_2,tRNA_anti-codon
k59_583280_1	640081.Dsui_2420	4.79e-16	77.4	COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,2VJ9A@28216|Betaproteobacteria,2KV3Z@206389|Rhodocyclales	206389|Rhodocyclales	C	UPF0313 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
k59_1397391_1	1249480.B649_01135	4.3e-29	114.0	COG0840@1|root,COG0840@2|Bacteria,1R5W9@1224|Proteobacteria,42SRV@68525|delta/epsilon subdivisions,2YR7J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	CZB,MCPsignal
k59_1397391_2	1537917.JU82_10865	1.62e-47	166.0	COG0464@1|root,COG0464@2|Bacteria,1N4ZI@1224|Proteobacteria,42NGJ@68525|delta/epsilon subdivisions,2YMAX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	ATPase (AAA	-	-	-	-	-	-	-	-	-	-	-	-	AAA
k59_1806602_1	865937.Gilli_0225	3.45e-19	91.7	28IBA@1|root,2Z8DT@2|Bacteria,4NI27@976|Bacteroidetes,1HZGB@117743|Flavobacteriia,2P79M@244698|Gillisia	976|Bacteroidetes	-	-	-	-	-	ko:K21012	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	PelG
k59_1055326_1	1387312.BAUS01000007_gene2229	5.25e-21	94.4	COG3271@1|root,COG3271@2|Bacteria,1RA3D@1224|Proteobacteria,2VQ1F@28216|Betaproteobacteria,2KNM1@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
k59_1463130_1	1502770.JQMG01000001_gene198	5.93e-71	216.0	COG0848@1|root,COG0848@2|Bacteria,1N0ZA@1224|Proteobacteria,2VUF4@28216|Betaproteobacteria,2KMSH@206350|Nitrosomonadales	206350|Nitrosomonadales	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
k59_583297_2	313606.M23134_07938	1.8e-18	84.3	COG1528@1|root,COG1528@2|Bacteria,4NGS7@976|Bacteroidetes,47Q0N@768503|Cytophagia	976|Bacteroidetes	P	Iron-storage protein	ftnA	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
k59_1633288_1	563040.Saut_0477	3.7e-10	62.0	COG1940@1|root,COG1940@2|Bacteria,1MU94@1224|Proteobacteria,42S50@68525|delta/epsilon subdivisions,2YP7Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	GK	COGs COG1940 Transcriptional regulator sugar kinase	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
k59_1633288_2	1537917.JU82_01370	6.54e-99	304.0	COG1543@1|root,COG1543@2|Bacteria,1R5SN@1224|Proteobacteria,42PSX@68525|delta/epsilon subdivisions	1224|Proteobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	2.4.1.18	ko:K16149	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000	-	GH57	-	DUF1957,Glyco_hydro_57
k59_1168639_2	1249480.B649_04975	5.02e-10	58.9	COG1286@1|root,COG1286@2|Bacteria,1NIBK@1224|Proteobacteria,42U0P@68525|delta/epsilon subdivisions,2YPS8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Colicin V production protein	cvpA	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
k59_1397405_1	749222.Nitsa_1481	7.4e-19	83.6	COG2863@1|root,COG2863@2|Bacteria,1PDTH@1224|Proteobacteria,42W2E@68525|delta/epsilon subdivisions,2YQDN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome c553	cccA	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C
k59_742281_1	1249480.B649_03465	2.47e-80	258.0	COG1256@1|root,COG1749@1|root,COG1256@2|Bacteria,COG1749@2|Bacteria,1MV2M@1224|Proteobacteria,42PBN@68525|delta/epsilon subdivisions,2YMGR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar hook-associated protein	flgK	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k59_813654_1	159087.Daro_2380	1.82e-31	117.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,2VHSU@28216|Betaproteobacteria,2KVHJ@206389|Rhodocyclales	206389|Rhodocyclales	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
k59_813654_2	640081.Dsui_2900	8.95e-47	163.0	COG0069@1|root,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,2VKQG@28216|Betaproteobacteria,2KWTH@206389|Rhodocyclales	206389|Rhodocyclales	E	Conserved region in glutamate synthase	-	-	2.1.1.21	ko:K22083	ko00680,ko01120,map00680,map01120	-	R01586	RC00554	ko00000,ko00001,ko01000	-	-	-	Glu_synthase
k59_552855_1	159087.Daro_2811	2.88e-35	138.0	COG0642@1|root,COG0784@1|root,COG2203@1|root,COG0784@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,Response_reg
k59_900638_1	366602.Caul_0959	3.88e-27	102.0	COG3162@1|root,COG3162@2|Bacteria,1MZF3@1224|Proteobacteria,2UFJ7@28211|Alphaproteobacteria,2KJG9@204458|Caulobacterales	204458|Caulobacterales	S	Protein of unknown function, DUF485	-	-	-	-	-	-	-	-	-	-	-	-	DUF485
k59_1370093_1	326298.Suden_1873	1.67e-35	127.0	2AJSF@1|root,30P8S@2|Bacteria,1PCR0@1224|Proteobacteria,42WCR@68525|delta/epsilon subdivisions,2YSXN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF2393)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2393
k59_1370093_2	1249480.B649_00955	1.92e-61	193.0	2AK36@1|root,31ASY@2|Bacteria,1Q62K@1224|Proteobacteria,42W11@68525|delta/epsilon subdivisions,2YQDG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF2393)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2393
k59_1193512_1	1537917.JU82_04265	4.31e-62	202.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,42QAG@68525|delta/epsilon subdivisions,2YNQV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,Response_reg
k59_1308323_2	1537917.JU82_04565	5.57e-50	160.0	COG1331@1|root,COG1331@2|Bacteria,1QZ2A@1224|Proteobacteria,42VGW@68525|delta/epsilon subdivisions,2YQEQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH,Thioredoxin_7
k59_1138501_1	709032.Sulku_0759	2.51e-186	528.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,42KZA@68525|delta/epsilon subdivisions,2YMA9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
k59_1260486_1	159087.Daro_0816	1.6e-109	337.0	COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,2VIEA@28216|Betaproteobacteria,2KUS5@206389|Rhodocyclales	206389|Rhodocyclales	C	nitrite reductase NAD(P)H	nirB	-	1.7.1.15	ko:K00362	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2
k59_785636_1	159087.Daro_3291	4.61e-111	327.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,2VJRR@28216|Betaproteobacteria,2KVQU@206389|Rhodocyclales	206389|Rhodocyclales	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
k59_77887_1	755732.Fluta_1673	5.77e-06	54.7	COG2911@1|root,COG3266@1|root,COG2911@2|Bacteria,COG3266@2|Bacteria,4PKFD@976|Bacteroidetes,1IKC5@117743|Flavobacteriia	976|Bacteroidetes	S	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
k59_257609_1	443598.AUFA01000020_gene3124	2.15e-19	87.8	COG1477@1|root,COG1477@2|Bacteria,1RIPS@1224|Proteobacteria,2V46K@28211|Alphaproteobacteria,3JT81@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
k59_257609_2	859657.RPSI07_2740	2.9e-51	169.0	COG4659@1|root,COG4659@2|Bacteria,1RFGW@1224|Proteobacteria,2VTI7@28216|Betaproteobacteria,1K7BS@119060|Burkholderiaceae	28216|Betaproteobacteria	C	PFAM FMN-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
k59_257609_3	426114.THI_1806	0.000135	43.1	28KDQ@1|root,2ZA05@2|Bacteria,1QVCG@1224|Proteobacteria,2VTD9@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_846272_2	572480.Arnit_2546	6.91e-37	139.0	COG1132@1|root,COG1132@2|Bacteria,1MVJD@1224|Proteobacteria,42PP5@68525|delta/epsilon subdivisions,2YN5G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	ABC transporter ATP-binding	pglK	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0006810,GO:0006869,GO:0008150,GO:0008152,GO:0008643,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015772,GO:0015920,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0022804,GO:0022857,GO:0022884,GO:0033036,GO:0034040,GO:0034645,GO:0036211,GO:0042623,GO:0042626,GO:0043170,GO:0043412,GO:0043413,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0051179,GO:0051234,GO:0055085,GO:0070085,GO:0071702,GO:0071704,GO:1901135,GO:1901137,GO:1901264,GO:1901505,GO:1901564,GO:1901566,GO:1901576	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k59_198012_1	946483.Cenrod_1796	1.37e-45	167.0	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria,4AA9F@80864|Comamonadaceae	28216|Betaproteobacteria	T	Histidine kinase	-	-	2.7.13.1	ko:K05962	-	-	-	-	ko00000,ko01000	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg
k59_1310803_1	536232.CLM_0373	1.66e-69	239.0	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,2490U@186801|Clostridia,36EG3@31979|Clostridiaceae	186801|Clostridia	Q	TIGRFAM amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_1196157_1	749222.Nitsa_1103	3.53e-96	302.0	COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,42M8I@68525|delta/epsilon subdivisions,2YN4J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	metE	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_1,Meth_synt_2
k59_1666849_1	1123487.KB892841_gene4303	1.04e-06	55.5	28JQB@1|root,2Z9G8@2|Bacteria,1QCH9@1224|Proteobacteria,2VJJF@28216|Betaproteobacteria,2KW13@206389|Rhodocyclales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_673466_1	1249480.B649_08795	7.46e-72	229.0	COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,42N7I@68525|delta/epsilon subdivisions,2YMDW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase
k59_198038_1	159087.Daro_3896	2.43e-33	127.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VJBX@28216|Betaproteobacteria,2KU9U@206389|Rhodocyclales	206389|Rhodocyclales	NT	Methyl-accepting chemotaxis protein	pilJ	-	-	ko:K02660	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	MCPsignal,PilJ
k59_198038_2	1304883.KI912532_gene1115	2.6e-39	146.0	COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VJSZ@28216|Betaproteobacteria,2KUBP@206389|Rhodocyclales	206389|Rhodocyclales	KNT	COG0643 Chemotaxis protein histidine kinase and related kinases	pilL	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,HATPase_c,Hpt,Response_reg
k59_1026872_1	1249480.B649_09460	4.53e-93	297.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,42KZI@68525|delta/epsilon subdivisions,2YR60@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Domain of unknown function (DUF3458_C) ARM repeats	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,Peptidase_M1
k59_673476_1	159087.Daro_0666	2.63e-178	517.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,2VIYB@28216|Betaproteobacteria,2KVTV@206389|Rhodocyclales	206389|Rhodocyclales	C	Malic enzyme	-	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
k59_1141640_1	392499.Swit_0505	2.02e-10	67.4	COG4206@1|root,COG4206@2|Bacteria,1QVV2@1224|Proteobacteria	2|Bacteria	H	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_785728_1	1537917.JU82_10955	1.6e-70	221.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,42M7V@68525|delta/epsilon subdivisions,2YMKI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
k59_312859_1	159087.Daro_3021	1.58e-126	372.0	COG2308@1|root,COG2308@2|Bacteria,1MUAD@1224|Proteobacteria,2VI55@28216|Betaproteobacteria,2KV17@206389|Rhodocyclales	206389|Rhodocyclales	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
k59_1080691_1	159087.Daro_0257	1.3e-30	117.0	COG1804@1|root,COG1804@2|Bacteria,1MW1H@1224|Proteobacteria,2VJJQ@28216|Betaproteobacteria,2KVW7@206389|Rhodocyclales	206389|Rhodocyclales	C	CoA-transferase family III	-	-	5.1.99.4	ko:K01796	ko00120,ko01100,ko04146,map00120,map01100,map04146	M00104	R08734,R08739	RC02345	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
k59_1080691_2	159087.Daro_1418	1.96e-14	73.2	28I9W@1|root,2Z8CH@2|Bacteria,1QCN6@1224|Proteobacteria,2VM9W@28216|Betaproteobacteria,2KV5B@206389|Rhodocyclales	206389|Rhodocyclales	S	SIR2-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
k59_372771_1	1317122.ATO12_18115	5.16e-16	77.4	COG1216@1|root,COG1216@2|Bacteria,4PMDQ@976|Bacteroidetes,1IKM4@117743|Flavobacteriia	976|Bacteroidetes	S	Glycosyl transferase family 2	-	-	-	ko:K13670	-	-	-	-	ko00000,ko01000	-	GT2	-	Glycos_transf_2
k59_1260622_1	709032.Sulku_0739	3.05e-80	263.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2YN6Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DNA mismatch repair MutS family	-	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_III,MutS_V
k59_1553735_1	614083.AWQR01000021_gene232	4.48e-28	118.0	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2WGK9@28216|Betaproteobacteria,4AK42@80864|Comamonadaceae	28216|Betaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,HAMP,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,Response_reg
k59_1080695_1	1249480.B649_02255	1.14e-118	344.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,42MVM@68525|delta/epsilon subdivisions,2YMMR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxC
k59_312870_1	1123518.ARWI01000001_gene577	4.22e-19	92.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,1RM9A@1236|Gammaproteobacteria,4604W@72273|Thiotrichales	72273|Thiotrichales	D	cell division protein	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
k59_903192_1	1132855.KB913035_gene2615	9.71e-122	351.0	COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,2VI1U@28216|Betaproteobacteria,2KKRE@206350|Nitrosomonadales	206350|Nitrosomonadales	H	PFAM UBA THIF-type NAD FAD binding protein	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
k59_143557_1	1100720.ALKN01000045_gene164	4.35e-25	110.0	COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,2VH0V@28216|Betaproteobacteria,4AAZJ@80864|Comamonadaceae	28216|Betaproteobacteria	KL	Helicase c2	dinG	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,ResIII
k59_1553772_1	1033734.CAET01000048_gene1718	2.48e-05	47.8	COG0664@1|root,COG0664@2|Bacteria,1U9VC@1239|Firmicutes,4HBWK@91061|Bacilli,1ZBJG@1386|Bacillus	91061|Bacilli	T	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
k59_1553772_2	1249480.B649_07060	3.14e-24	94.4	COG1959@1|root,COG1959@2|Bacteria,1MZ1C@1224|Proteobacteria,42SPF@68525|delta/epsilon subdivisions	1224|Proteobacteria	K	TIGRFAM transcriptional regulator, Rrf2 family	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
k59_257735_1	1123514.KB905899_gene1910	2.15e-20	88.6	COG2836@1|root,COG2836@2|Bacteria,1RIGJ@1224|Proteobacteria,1S5V1@1236|Gammaproteobacteria,460UR@72273|Thiotrichales	72273|Thiotrichales	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
k59_257735_2	273526.SMDB11_4583	8.74e-27	106.0	COG3709@1|root,COG3709@2|Bacteria,1RGXZ@1224|Proteobacteria,1S3VA@1236|Gammaproteobacteria,3ZZMD@613|Serratia	1236|Gammaproteobacteria	F	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)	phnN	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006015,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019200,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019634,GO:0019637,GO:0019674,GO:0019693,GO:0033863,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046391,GO:0046483,GO:0046496,GO:0046835,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.23	ko:K05774	ko00030,map00030	-	R06836	RC00002	ko00000,ko00001,ko01000	-	-	iAF1260.b4094,iB21_1397.B21_03926,iBWG_1329.BWG_3809,iECBD_1354.ECBD_3936,iECB_1328.ECB_03966,iECDH10B_1368.ECDH10B_4285,iECDH1ME8569_1439.ECDH1ME8569_3953,iECD_1391.ECD_03966,iEKO11_1354.EKO11_4224,iEcDH1_1363.EcDH1_3897,iEcolC_1368.EcolC_3932,iJO1366.b4094,iSSON_1240.SSON_4270,iUMNK88_1353.UMNK88_4960,iY75_1357.Y75_RS21315	AAA_18,Guanylate_kin
k59_1847361_1	1249480.B649_05840	4.26e-67	210.0	COG2885@1|root,COG2885@2|Bacteria,1MZKA@1224|Proteobacteria,42U2D@68525|delta/epsilon subdivisions,2YQ5B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
k59_1847361_2	641491.DND132_0567	1.53e-16	84.3	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2WIUS@28221|Deltaproteobacteria,2M92Z@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	SMART Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
k59_1373086_1	1537917.JU82_05945	1.71e-52	165.0	COG0238@1|root,COG0238@2|Bacteria,1MZ8U@1224|Proteobacteria,42VJQ@68525|delta/epsilon subdivisions,2YPHN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
k59_257755_2	709032.Sulku_0084	1.24e-64	199.0	2AIZZ@1|root,319I0@2|Bacteria,1Q2U7@1224|Proteobacteria,42W9A@68525|delta/epsilon subdivisions,2YQB5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1373091_2	1249480.B649_08780	2.47e-62	194.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
k59_257760_1	580332.Slit_0176	5.14e-138	401.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,2VH57@28216|Betaproteobacteria,44UYB@713636|Nitrosomonadales	28216|Betaproteobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0000097,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0036094,GO:0036293,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0055086,GO:0070482,GO:0071268,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
k59_198172_1	709032.Sulku_0052	4.51e-117	347.0	COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,42M8Q@68525|delta/epsilon subdivisions,2YMSH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome c oxidase accessory protein	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
k59_198172_2	1537917.JU82_00580	2.49e-89	267.0	COG1961@1|root,COG1961@2|Bacteria,1Q5XK@1224|Proteobacteria,42TRW@68525|delta/epsilon subdivisions,2YQ0Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	PFAM Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_7,Resolvase
k59_257764_1	159087.Daro_2801	6.96e-72	239.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2VHCZ@28216|Betaproteobacteria,2KVY2@206389|Rhodocyclales	206389|Rhodocyclales	P	AcrB/AcrD/AcrF family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
k59_257764_2	159087.Daro_2801	9.22e-44	158.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2VHCZ@28216|Betaproteobacteria,2KVY2@206389|Rhodocyclales	206389|Rhodocyclales	P	AcrB/AcrD/AcrF family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
k59_673619_1	1537917.JU82_03925	8.21e-97	298.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42MBE@68525|delta/epsilon subdivisions,2YNGN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	abc transporter atp-binding protein	-	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k59_143629_1	709032.Sulku_0791	9.66e-60	193.0	COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,42N1M@68525|delta/epsilon subdivisions,2YN3T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metXA	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
k59_143629_2	1537917.JU82_04815	5.03e-52	175.0	COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,43DRR@68525|delta/epsilon subdivisions,2YMSV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	o-acetylhomoserine	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
k59_556650_1	1537917.JU82_00225	9.32e-44	154.0	COG3437@1|root,COG3437@2|Bacteria,1QYD6@1224|Proteobacteria,43CBH@68525|delta/epsilon subdivisions,2YTB6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	cheY-homologous receiver domain	-	-	3.1.1.61,3.5.1.44	ko:K03412,ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	Response_reg
k59_1553854_1	1537917.JU82_02080	8.04e-71	235.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,42NKH@68525|delta/epsilon subdivisions,2YMVS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the helicase family. UvrD subfamily	addA	-	3.1.11.5	ko:K03582	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C
k59_1553854_2	1249480.B649_11090	5.01e-65	219.0	COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,1QUIU@1224|Proteobacteria,42M7I@68525|delta/epsilon subdivisions,2YMX0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG3893 inactivated superfamily I helicase	addB	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
k59_1260745_1	1304883.KI912532_gene300	1.21e-111	340.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2VH4I@28216|Betaproteobacteria,2KV7T@206389|Rhodocyclales	206389|Rhodocyclales	L	DNA helicase	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_556671_1	709032.Sulku_0856	2.15e-123	357.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,42PKA@68525|delta/epsilon subdivisions,2YP35@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the protein N5-glutamine methyltransferase family	hemK	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
k59_556671_2	1537917.JU82_11315	4.72e-28	110.0	COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,42P1M@68525|delta/epsilon subdivisions,2YN96@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Peptidase M48	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
k59_432903_1	159087.Daro_1867	2.62e-18	83.2	COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,2VHBQ@28216|Betaproteobacteria,2KUY6@206389|Rhodocyclales	206389|Rhodocyclales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_846419_1	709032.Sulku_0500	1.97e-75	226.0	COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,42TMU@68525|delta/epsilon subdivisions,2YPEI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
k59_1667010_1	159087.Daro_3620	1.79e-82	260.0	2CC4B@1|root,3267W@2|Bacteria,1RJP5@1224|Proteobacteria,2VU2U@28216|Betaproteobacteria,2KZ3X@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1553894_1	1249480.B649_10290	1.92e-180	509.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42MNF@68525|delta/epsilon subdivisions,2YMW2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_432924_1	387093.SUN_1147	8.99e-113	339.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,42MJE@68525|delta/epsilon subdivisions,2YN7F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	actP	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
k59_785944_1	159087.Daro_0578	1.76e-184	532.0	COG1982@1|root,COG1982@2|Bacteria,1MWK4@1224|Proteobacteria,2VIJQ@28216|Betaproteobacteria,2KV3G@206389|Rhodocyclales	206389|Rhodocyclales	E	COG1982 Arginine lysine ornithine decarboxylases	adiA	-	4.1.1.19	ko:K01584	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C,OKR_DC_1_N
k59_372905_1	709032.Sulku_0014	1.05e-115	345.0	COG3203@1|root,COG3203@2|Bacteria,1QZ2N@1224|Proteobacteria,42QVI@68525|delta/epsilon subdivisions,2YP28@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_673705_1	748247.AZKH_4039	1.77e-99	294.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,2WEB3@28216|Betaproteobacteria,2KZYX@206389|Rhodocyclales	206389|Rhodocyclales	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_1260819_2	709032.Sulku_1412	3.49e-26	97.4	2AK4P@1|root,31AUI@2|Bacteria,1Q664@1224|Proteobacteria,42X10@68525|delta/epsilon subdivisions,2YQR8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1260819_3	1537917.JU82_08205	3.34e-53	182.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,42N1K@68525|delta/epsilon subdivisions,2YMYX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1g,tRNA_bind
k59_372923_1	1336245.JAGO01000013_gene1575	4.15e-63	207.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,1RN65@1236|Gammaproteobacteria,1XHMA@135619|Oceanospirillales	135619|Oceanospirillales	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
k59_1847507_1	1249480.B649_06480	1.41e-161	466.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42PMU@68525|delta/epsilon subdivisions,2YNHE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4
k59_1373211_1	69279.BG36_20870	3.76e-78	253.0	COG3170@1|root,COG3170@2|Bacteria,1QVEE@1224|Proteobacteria,2TWDG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	NU	Phage P22-like portal protein	-	-	-	-	-	-	-	-	-	-	-	-	P22_portal
k59_1847516_1	1120999.JONM01000026_gene1542	6.41e-37	142.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KQ7Y@206351|Neisseriales	206351|Neisseriales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,EAL,GAF,GGDEF,PAS_3,dCache_1
k59_556791_1	264198.Reut_A2365	4.19e-06	47.8	COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,2VHG5@28216|Betaproteobacteria,1KFH3@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_int_SAM_3,Phage_integrase
k59_200825_1	709032.Sulku_2067	7.11e-79	256.0	COG0642@1|root,COG3850@1|root,COG2205@2|Bacteria,COG3850@2|Bacteria,1NRP8@1224|Proteobacteria,42Z1P@68525|delta/epsilon subdivisions,2YRFA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	HAMP domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k59_614763_1	582744.Msip34_2630	1.1e-43	149.0	2AQI0@1|root,31FQP@2|Bacteria,1RI31@1224|Proteobacteria,2VUDX@28216|Betaproteobacteria,2KMU0@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_614763_2	1502770.JQMG01000001_gene875	1.89e-70	216.0	COG1335@1|root,COG1335@2|Bacteria,1MU5N@1224|Proteobacteria,2VUBT@28216|Betaproteobacteria,2KMRA@206350|Nitrosomonadales	206350|Nitrosomonadales	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
k59_497717_1	1415755.JQLV01000001_gene2003	6.07e-32	118.0	COG1949@1|root,COG1949@2|Bacteria,1R9WX@1224|Proteobacteria,1S217@1236|Gammaproteobacteria,1XJ7F@135619|Oceanospirillales	135619|Oceanospirillales	L	3'-to-5' exoribonuclease specific for small oligoribonucleotides	orn	-	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
k59_259794_1	387093.SUN_0965	5.73e-75	233.0	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,42P2E@68525|delta/epsilon subdivisions,2YNPW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
k59_676404_1	234267.Acid_2243	2.59e-49	173.0	COG0028@1|root,COG0028@2|Bacteria,3Y3TV@57723|Acidobacteria	57723|Acidobacteria	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_676404_2	1121013.P873_02700	4.88e-10	59.3	COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,1S6D0@1236|Gammaproteobacteria,1X6HQ@135614|Xanthomonadales	135614|Xanthomonadales	S	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate	kdsC	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
k59_1609572_1	1123487.KB892835_gene3329	4.91e-11	63.2	COG1176@1|root,COG1176@2|Bacteria,1MU1Y@1224|Proteobacteria,2VK8I@28216|Betaproteobacteria,2KUGN@206389|Rhodocyclales	206389|Rhodocyclales	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02054	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
k59_919443_1	159087.Daro_1968	6.54e-94	279.0	COG0412@1|root,COG0412@2|Bacteria,1QVEZ@1224|Proteobacteria,2VWXD@28216|Betaproteobacteria,2KXMU@206389|Rhodocyclales	206389|Rhodocyclales	Q	Dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1327565_1	1249480.B649_07775	1.93e-134	393.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2YM8S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
k59_919456_1	159087.Daro_1415	4.45e-74	229.0	COG1348@1|root,COG1348@2|Bacteria,1MVTE@1224|Proteobacteria,2VIK4@28216|Betaproteobacteria,2KUME@206389|Rhodocyclales	206389|Rhodocyclales	P	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein	nifH	-	1.18.6.1	ko:K02588	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_NifH
k59_692924_1	159087.Daro_3759	1.4e-94	285.0	COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,2VJN7@28216|Betaproteobacteria,2KUZZ@206389|Rhodocyclales	206389|Rhodocyclales	T	Signal transduction histidine kinase, nitrogen specific	ntrB	-	2.7.13.3	ko:K07708	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4
k59_1212792_1	1537917.JU82_03325	5.65e-63	208.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,42M09@68525|delta/epsilon subdivisions,2YMWR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
k59_1327589_1	1249480.B649_09145	4.49e-67	210.0	COG1317@1|root,COG1317@2|Bacteria,1NJAJ@1224|Proteobacteria,42P5I@68525|delta/epsilon subdivisions,2YQ57@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar assembly protein FliH	fliH	-	-	ko:K02411	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliH
k59_1279722_1	1163617.SCD_n02043	4.1e-110	323.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,2VR34@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Reversible hydration of carbon dioxide	cynT	GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008150,GO:0008270,GO:0015976,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0046872,GO:0046914	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
k59_1572584_1	709032.Sulku_0432	4.44e-99	309.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2YMW4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_1742289_1	1249480.B649_04850	6.74e-119	364.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,42MD4@68525|delta/epsilon subdivisions,2YNMI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	PFAM Helicase conserved C-terminal domain	hrpB	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
k59_1572603_1	709032.Sulku_2414	8.67e-26	106.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,42MMR@68525|delta/epsilon subdivisions,2YMF0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	GM	Polysaccharide biosynthesis protein	pglF	-	4.2.1.135	ko:K15912	ko00520,map00520	-	-	-	ko00000,ko00001,ko01000	-	-	-	Polysacc_synt_2
k59_1572603_2	1537917.JU82_02320	5.14e-38	141.0	COG1287@1|root,COG1287@2|Bacteria,1R8YG@1224|Proteobacteria,43BIB@68525|delta/epsilon subdivisions,2YT8Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Oligosaccharide transferase	-	-	2.4.99.18	ko:K07151	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	STT3
k59_1624004_1	381764.Fnod_1277	1.72e-12	73.6	COG0642@1|root,COG3829@1|root,COG2205@2|Bacteria,COG3829@2|Bacteria,2GCUP@200918|Thermotogae	200918|Thermotogae	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,HisKA_7TM,Hpt,PAS_4,PAS_9,Response_reg
k59_858993_1	709032.Sulku_0712	3.84e-120	367.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,42MPZ@68525|delta/epsilon subdivisions,2YM8C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k59_1096860_1	1123401.JHYQ01000009_gene2236	1.08e-32	122.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,1RQYC@1236|Gammaproteobacteria,460NX@72273|Thiotrichales	72273|Thiotrichales	I	Acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k59_1096860_2	390235.PputW619_0078	5.73e-47	158.0	COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,1S3UD@1236|Gammaproteobacteria,1YXJJ@136845|Pseudomonas putida group	1236|Gammaproteobacteria	E	D,D-heptose 1,7-bisphosphate phosphatase	gmhB	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iJN746.PP_0059	Hydrolase_like
k59_1096862_1	159087.Daro_0525	3e-28	103.0	COG2345@1|root,COG2345@2|Bacteria,1N9W3@1224|Proteobacteria,2VWG0@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_35222_1	754476.Q7A_1027	9.51e-74	234.0	COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,1RNVF@1236|Gammaproteobacteria,45ZZ3@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
k59_35222_2	1316927.ATKI01000011_gene1414	2.52e-34	130.0	COG0352@1|root,COG0494@1|root,COG0352@2|Bacteria,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,1RS3S@1236|Gammaproteobacteria,1YPEM@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	HL	NUDIX domain	mutT	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008413,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017110,GO:0030145,GO:0033554,GO:0034641,GO:0035539,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044715,GO:0044716,GO:0046483,GO:0046872,GO:0046914,GO:0047429,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	iE2348C_1286.E2348C_0104,iSDY_1059.SDY_0129	NUDIX,NUDIX_4,TMP-TENI
k59_1798493_1	694427.Palpr_1347	2.39e-50	169.0	2AINN@1|root,31954@2|Bacteria,4P6MS@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
k59_272085_1	387093.SUN_1263	3.71e-87	267.0	COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,42YUF@68525|delta/epsilon subdivisions,2YR9U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs	-	-	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
k59_160167_1	1165841.SULAR_00060	3.27e-42	154.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2YMAI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k59_160167_2	1165841.SULAR_00065	3.08e-48	161.0	COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,42MJK@68525|delta/epsilon subdivisions,2YMV3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0400	LYTB
k59_1624048_2	1565314.OA34_02895	4.44e-09	58.2	COG0679@1|root,COG0679@2|Bacteria,1N5NC@1224|Proteobacteria,42PYE@68525|delta/epsilon subdivisions,2YMUI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM Auxin Efflux Carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
k59_983719_1	709032.Sulku_1063	1.74e-31	124.0	COG0513@1|root,COG0513@2|Bacteria	2|Bacteria	L	helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	CpcD,DbpA
k59_326025_2	1249480.B649_01535	1.8e-57	202.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YMHP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF,PAS_9
k59_1624070_1	709032.Sulku_0516	4.15e-116	348.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,42M6V@68525|delta/epsilon subdivisions,2YM9I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k59_272098_1	194867.ALBQ01000005_gene1726	7.6e-06	49.7	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2TQR7@28211|Alphaproteobacteria,2K0WT@204457|Sphingomonadales	204457|Sphingomonadales	NT	Single cache domain 3	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,MCPsignal,sCache_3_3
k59_272098_2	1231391.AMZF01000006_gene2693	4.32e-145	437.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2VHBY@28216|Betaproteobacteria,3T1P5@506|Alcaligenaceae	28216|Betaproteobacteria	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_1506044_2	1348114.OM33_00255	6.44e-08	55.1	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2Q173@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	T	COG2199 FOG GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_220036_1	1537917.JU82_06895	4.7e-88	282.0	COG0715@1|root,COG0834@1|root,COG4191@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PNA@68525|delta/epsilon subdivisions,2YTBI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EPT	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,NMT1,SBP_bac_3
k59_1802260_2	196367.JNFG01000200_gene3052	8.37e-103	305.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,2VI4J@28216|Betaproteobacteria,1JZYI@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
k59_163261_1	1123367.C666_06600	2.09e-97	295.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,2VI46@28216|Betaproteobacteria,2KVJW@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	paaK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
k59_163261_2	159087.Daro_0373	6.05e-94	275.0	COG2050@1|root,COG2050@2|Bacteria,1RH35@1224|Proteobacteria,2VRC2@28216|Betaproteobacteria,2KWSU@206389|Rhodocyclales	206389|Rhodocyclales	Q	phenylacetic acid degradation protein	paaI	-	-	ko:K02614	ko00360,map00360	-	R09840	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	4HBT
k59_163261_3	159087.Daro_0372	2.05e-16	77.8	COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2VK75@28216|Betaproteobacteria,2KVQR@206389|Rhodocyclales	206389|Rhodocyclales	I	3-hydroxyacyl-CoA dehydrogenase	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
k59_1216670_1	1537917.JU82_10785	1.61e-28	104.0	COG1826@1|root,COG1826@2|Bacteria,1NGDP@1224|Proteobacteria,42VNG@68525|delta/epsilon subdivisions,2YQ9F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
k59_1216670_2	1249480.B649_01050	1.5e-57	192.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,42MTY@68525|delta/epsilon subdivisions,2YMHI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
k59_1163260_1	709032.Sulku_2313	1.08e-136	395.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,42MD6@68525|delta/epsilon subdivisions,2YMXT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petB	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
k59_1747117_1	1537917.JU82_10560	2.29e-95	295.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,42MVQ@68525|delta/epsilon subdivisions,2YMEZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CO	Thiol disulfide interchange protein	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin,Thioredoxin_2,Thioredoxin_7
k59_924125_1	1537917.JU82_02310	3.3e-144	415.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42MJD@68525|delta/epsilon subdivisions,2YMVU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	pglE	-	2.6.1.34	ko:K15910	ko00520,map00520	-	-	-	ko00000,ko00001,ko01000	-	-	-	DegT_DnrJ_EryC1
k59_275847_1	1249627.D779_3943	4.63e-30	122.0	COG3316@1|root,COG3316@2|Bacteria,1QE29@1224|Proteobacteria,1T5ZZ@1236|Gammaproteobacteria,1X2WN@135613|Chromatiales	135613|Chromatiales	L	Transposase IS66 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66
k59_862786_1	1249480.B649_07410	1.74e-128	379.0	COG1538@1|root,COG1538@2|Bacteria,1MYX2@1224|Proteobacteria,42MHZ@68525|delta/epsilon subdivisions,2YNGC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	Outer membrane efflux protein	-	-	-	ko:K12543	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	1.B.17,3.A.1.109.4	-	-	OEP,OmpA,TSP_3
k59_1458874_1	1249480.B649_00045	2.48e-91	283.0	COG0784@1|root,COG5001@1|root,COG0784@2|Bacteria,COG5001@2|Bacteria,1MUNI@1224|Proteobacteria	1224|Proteobacteria	T	COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3369,EAL,GGDEF,Response_reg
k59_697107_1	1249480.B649_09360	9.34e-136	387.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,42N5B@68525|delta/epsilon subdivisions,2YMWV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
k59_809009_1	387092.NIS_1666	4.76e-09	58.2	COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,42NI1@68525|delta/epsilon subdivisions,2YMHQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
k59_809009_2	1355368.JART01000001_gene833	2.1e-52	172.0	COG3545@1|root,COG3545@2|Bacteria,1RDB7@1224|Proteobacteria,42RXC@68525|delta/epsilon subdivisions,2YP4P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	esterase of the alpha beta hydrolase fold	-	-	-	ko:K07002	-	-	-	-	ko00000	-	-	-	Ser_hydrolase
k59_809009_3	1537917.JU82_00625	1.57e-16	77.8	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,42MHX@68525|delta/epsilon subdivisions,2YMXF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
k59_1685793_2	187272.Mlg_1322	6.55e-05	48.9	COG1028@1|root,COG1028@2|Bacteria,1MW4W@1224|Proteobacteria,1RRSA@1236|Gammaproteobacteria,1WXS6@135613|Chromatiales	135613|Chromatiales	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_578361_1	1537917.JU82_03275	5.9e-156	457.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42MCY@68525|delta/epsilon subdivisions,2YMB3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB1	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
k59_633970_1	709032.Sulku_1522	3.58e-28	109.0	COG2199@1|root,COG2199@2|Bacteria,1Q4Z5@1224|Proteobacteria,4306K@68525|delta/epsilon subdivisions,2YRSF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	diguanylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_633970_2	1249480.B649_06645	5.69e-166	471.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,42M5V@68525|delta/epsilon subdivisions,2YM81@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Cysteine desulfurase	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
k59_809020_2	999541.bgla_1g17000	4.5e-21	92.4	COG3511@1|root,COG3511@2|Bacteria,1MVNS@1224|Proteobacteria,2VMDC@28216|Betaproteobacteria,1KGU4@119060|Burkholderiaceae	28216|Betaproteobacteria	M	acid phosphatase	acpA	-	-	-	-	-	-	-	-	-	-	-	Phosphoesterase
k59_924246_1	1123248.KB893326_gene1313	2.16e-25	110.0	COG0642@1|root,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,1IQ4P@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
k59_634017_1	709032.Sulku_0894	1.07e-106	333.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2YN6Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DNA mismatch repair MutS family	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_III,MutS_V
k59_988643_2	1537917.JU82_03990	3.17e-70	225.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,42N6C@68525|delta/epsilon subdivisions,2YMY6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
k59_452775_1	1249480.B649_05430	3.33e-35	134.0	COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,1QTS5@1224|Proteobacteria,42MPY@68525|delta/epsilon subdivisions,2YMV7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	phosphate acetyltransferase	pta	-	2.3.1.8	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,DRTGG,PTA_PTB
k59_1577618_1	1537917.JU82_06005	3.27e-115	354.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,42MMV@68525|delta/epsilon subdivisions,2YMV9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k59_1868971_2	709032.Sulku_0603	3.05e-103	300.0	2BM55@1|root,32FNN@2|Bacteria,1Q0P6@1224|Proteobacteria,42SB7@68525|delta/epsilon subdivisions,2YPGR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	DNA replication regulator	hobA	-	-	-	-	-	-	-	-	-	-	-	HobA
k59_738278_2	1234595.C725_1320	4.13e-05	50.8	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TS6B@28211|Alphaproteobacteria,4BPB3@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	O	Trypsin	htrA2	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030163,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051603,GO:0061077,GO:0070011,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564,GO:1901565,GO:1901575	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
k59_1332698_1	1123393.KB891329_gene1049	7e-61	204.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,2VJ9H@28216|Betaproteobacteria,1KSQ9@119069|Hydrogenophilales	119069|Hydrogenophilales	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
k59_578467_1	1537917.JU82_05290	2.23e-76	232.0	COG0726@1|root,COG0726@2|Bacteria,1RCWD@1224|Proteobacteria,42R0P@68525|delta/epsilon subdivisions,2YPBW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
k59_1685888_1	709032.Sulku_0635	1.52e-70	228.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42P4R@68525|delta/epsilon subdivisions,2YM92@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	DUF3365,MCPsignal
k59_1577656_1	1304883.KI912532_gene122	8.63e-102	315.0	COG2199@1|root,COG3706@2|Bacteria,1MXAW@1224|Proteobacteria,2VK79@28216|Betaproteobacteria,2KUEF@206389|Rhodocyclales	206389|Rhodocyclales	T	GGDEF domain	-	-	2.7.7.65	ko:K13590	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF
k59_330286_1	543728.Vapar_4182	1.43e-37	144.0	COG1256@1|root,COG1749@1|root,COG1256@2|Bacteria,COG1749@2|Bacteria,1MV2M@1224|Proteobacteria,2VH02@28216|Betaproteobacteria,4ABDS@80864|Comamonadaceae	28216|Betaproteobacteria	N	Belongs to the flagella basal body rod proteins family	flgK	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k59_1332733_2	1249480.B649_05250	5.02e-30	108.0	COG3326@1|root,COG3326@2|Bacteria,1N6YM@1224|Proteobacteria,42TQY@68525|delta/epsilon subdivisions	1224|Proteobacteria	K	Protein of unknown function (DUF1294)	-	-	-	-	-	-	-	-	-	-	-	-	CSD,DUF1294
k59_1393424_1	709032.Sulku_2232	1.5e-64	221.0	COG1195@1|root,COG3210@1|root,COG1195@2|Bacteria,COG3210@2|Bacteria,1R4VM@1224|Proteobacteria,43CFZ@68525|delta/epsilon subdivisions	1224|Proteobacteria	U	amine dehydrogenase activity	mshQ	-	-	ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	Bactofilin,Laminin_G_3,PA14
k59_96017_1	59196.RICGR_1080	2.78e-123	394.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,1JD5C@118969|Legionellales	118969|Legionellales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_1216949_1	709032.Sulku_0106	2.23e-24	95.5	COG0597@1|root,COG0597@2|Bacteria,1Q1GU@1224|Proteobacteria,42TMD@68525|delta/epsilon subdivisions,2YPZS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
k59_1216949_2	1537917.JU82_00535	1.83e-117	347.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,42M6I@68525|delta/epsilon subdivisions,2YMNB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_1332776_1	1537917.JU82_01740	1.24e-155	445.0	COG0387@1|root,COG0387@2|Bacteria,1N1MR@1224|Proteobacteria,42MUQ@68525|delta/epsilon subdivisions,2YMUB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Sodium calcium exchanger membrane	-	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
k59_1332776_2	944547.ABLL_2147	6.33e-43	148.0	COG0598@1|root,COG0598@2|Bacteria,1MWMP@1224|Proteobacteria,42KZB@68525|delta/epsilon subdivisions,2YN63@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
k59_1628838_2	1249480.B649_05320	8.33e-100	292.0	29668@1|root,2ZTGD@2|Bacteria,1Q60I@1224|Proteobacteria,4326Q@68525|delta/epsilon subdivisions,2YSIU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1577754_1	1132855.KB913035_gene258	5.01e-111	354.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,2VHUY@28216|Betaproteobacteria,2KM55@206350|Nitrosomonadales	206350|Nitrosomonadales	E	glutamate synthase, alpha subunit domain protein	-	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_276122_1	1123326.JFBL01000002_gene1644	1.99e-49	165.0	COG0352@1|root,COG0352@2|Bacteria,1Q57E@1224|Proteobacteria,42T8S@68525|delta/epsilon subdivisions,2YPQM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Thiamine monophosphate synthase	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
k59_39548_1	1085623.GNIT_3238	2.33e-40	143.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,1RMJJ@1236|Gammaproteobacteria,465VY@72275|Alteromonadaceae	1236|Gammaproteobacteria	KT	Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
k59_1577775_1	709032.Sulku_0927	2.44e-108	332.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42MS0@68525|delta/epsilon subdivisions,2YMTX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,dCache_3
k59_390621_1	1304883.KI912532_gene404	8.68e-83	262.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VI6G@28216|Betaproteobacteria,2KUBK@206389|Rhodocyclales	206389|Rhodocyclales	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	lpd	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
k59_390621_2	1304883.KI912532_gene403	1.24e-152	442.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,2VIHA@28216|Betaproteobacteria,2KV9Z@206389|Rhodocyclales	206389|Rhodocyclales	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceF	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
k59_634182_1	1537917.JU82_11875	2.58e-128	393.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,42N8X@68525|delta/epsilon subdivisions,2YMGZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_39562_1	709032.Sulku_0245	2.67e-89	268.0	COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,42M1Y@68525|delta/epsilon subdivisions,2YMJA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Hydrolase	aguB	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
k59_39562_2	709032.Sulku_0244	5.66e-33	121.0	COG1344@1|root,COG1344@2|Bacteria,1P7ZB@1224|Proteobacteria,42QS1@68525|delta/epsilon subdivisions,2YNAV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	flaC	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
k59_1792975_1	1249480.B649_02120	2.71e-138	413.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2YMW4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_569161_2	159087.Daro_2906	1.19e-87	264.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,2VJZP@28216|Betaproteobacteria,2KVE7@206389|Rhodocyclales	206389|Rhodocyclales	M	peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3
k59_854336_1	709032.Sulku_1005	1.66e-109	323.0	COG0694@1|root,COG0822@1|root,COG0694@2|Bacteria,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,42MT6@68525|delta/epsilon subdivisions,2YMXY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CO	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins	-	-	-	ko:K13819	-	-	-	-	ko00000	-	-	-	Fer2_BFD,NifU,NifU_N
k59_1091035_1	1249480.B649_03045	8.85e-97	288.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,42SCV@68525|delta/epsilon subdivisions,2YPRK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar motor	motB	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
k59_854339_1	159087.Daro_0834	9.8e-76	231.0	COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,2VMXI@28216|Betaproteobacteria,2KWA5@206389|Rhodocyclales	206389|Rhodocyclales	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
k59_854339_2	159087.Daro_0833	7.97e-45	160.0	COG3850@1|root,COG3850@2|Bacteria,1MWZT@1224|Proteobacteria,2VIFM@28216|Betaproteobacteria,2KV4T@206389|Rhodocyclales	206389|Rhodocyclales	T	Type IV pili methyl-accepting chemotaxis transducer N-term	-	-	2.7.13.3	ko:K07673	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HAMP,HATPase_c,HisKA_3,PilJ
k59_1320474_1	1249480.B649_05240	1.12e-60	204.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,42NU9@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding	iorB	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,TAT_signal
k59_1320474_2	1249480.B649_05235	9.03e-62	197.0	COG1975@1|root,COG1975@2|Bacteria,1MXKU@1224|Proteobacteria,42QUY@68525|delta/epsilon subdivisions,2YSUC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	XdhC and CoxI family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
k59_506460_1	1249480.B649_05775	1.61e-82	250.0	COG0546@1|root,COG0546@2|Bacteria,1NDKE@1224|Proteobacteria,42SW4@68525|delta/epsilon subdivisions,2YPI4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	HAD-superfamily hydrolase, subfamily IA, variant 1	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_1676288_1	709032.Sulku_2057	1.26e-115	355.0	COG1251@1|root,COG1740@1|root,COG1251@2|Bacteria,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,42PSD@68525|delta/epsilon subdivisions,2YNBA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	hydrogenase (NiFe) small subunit HydA	-	-	1.12.5.1	ko:K05927	-	-	-	-	ko00000,ko01000	-	-	-	Fer2_BFD,NiFe_hyd_SSU_C,Oxidored_q6,Pyr_redox_2
k59_798534_1	159087.Daro_2452	6.19e-42	158.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,2VK2H@28216|Betaproteobacteria,2KV2V@206389|Rhodocyclales	206389|Rhodocyclales	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N,IF2_assoc
k59_506464_1	1249480.B649_05335	1.19e-116	353.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42MS0@68525|delta/epsilon subdivisions,2YMTX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_267030_1	1355368.JART01000002_gene2277	3.79e-60	204.0	COG3437@1|root,COG3437@2|Bacteria,1QUN9@1224|Proteobacteria,42PB6@68525|delta/epsilon subdivisions,2YR9Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,PAS_9
k59_1617550_1	1249480.B649_11065	7.92e-24	99.4	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42MFK@68525|delta/epsilon subdivisions,2YN87@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Abc transporter	nikZ	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k59_1617550_2	1537917.JU82_02000	1.99e-86	259.0	COG0546@1|root,COG0546@2|Bacteria,1RBMZ@1224|Proteobacteria,42RG3@68525|delta/epsilon subdivisions,2YP44@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Hydrolase	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_1566014_1	159087.Daro_1223	2.59e-25	97.4	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,2VR4P@28216|Betaproteobacteria,2KWEZ@206389|Rhodocyclales	206389|Rhodocyclales	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
k59_1566014_2	159087.Daro_1224	3.58e-152	448.0	COG4166@1|root,COG4166@2|Bacteria,1R87R@1224|Proteobacteria,2VKFJ@28216|Betaproteobacteria,2KU6I@206389|Rhodocyclales	206389|Rhodocyclales	E	extracellular solute-binding protein	oppA	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
k59_1206343_1	159087.Daro_2872	5.9e-26	105.0	COG3203@1|root,COG3203@2|Bacteria,1Q1XX@1224|Proteobacteria,2VRRG@28216|Betaproteobacteria,2KVVA@206389|Rhodocyclales	206389|Rhodocyclales	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
k59_1206343_2	159087.Daro_2871	1.25e-79	238.0	COG0226@1|root,COG0226@2|Bacteria,1N7RX@1224|Proteobacteria,2VW7C@28216|Betaproteobacteria,2KX95@206389|Rhodocyclales	206389|Rhodocyclales	P	ABC-type phosphate transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1734834_1	709032.Sulku_1168	4.28e-148	426.0	COG3200@1|root,COG3200@2|Bacteria,1MUWF@1224|Proteobacteria,42MB5@68525|delta/epsilon subdivisions,2YMRI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	phospho-2-dehydro-3-deoxyheptonate aldolase	aroG	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0134	DAHP_synth_2
k59_506495_1	159087.Daro_4156	9.94e-59	191.0	COG5652@1|root,COG5652@2|Bacteria,1PJUW@1224|Proteobacteria,2VHEZ@28216|Betaproteobacteria,2KW9S@206389|Rhodocyclales	206389|Rhodocyclales	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
k59_506495_2	1304883.KI912532_gene872	1.95e-55	192.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,2KUDV@206389|Rhodocyclales	206389|Rhodocyclales	P	COG0474 Cation transport ATPase	-	-	-	-	-	-	-	-	-	-	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
k59_1383405_1	709032.Sulku_2612	1.7e-68	214.0	COG0348@1|root,COG0348@2|Bacteria,1MWR5@1224|Proteobacteria,42NMJ@68525|delta/epsilon subdivisions,2YMIN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Ferredoxin-type protein, NapH MauN family	napH	-	-	ko:K02574	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_10,Fer4_5,Fer4_6
k59_1383405_2	709032.Sulku_2611	6.07e-52	170.0	COG0437@1|root,COG0437@2|Bacteria,1N9WY@1224|Proteobacteria,42MXM@68525|delta/epsilon subdivisions,2YMAD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	TIGRFAM MauM NapG family ferredoxin-type protein	napG	-	-	ko:K02573	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_4,Fer4_7
k59_1040521_1	709032.Sulku_2546	5.35e-160	464.0	COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,42P71@68525|delta/epsilon subdivisions,2YNAA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Phospholipid glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5,Acyltransferase
k59_442804_1	1249480.B649_11795	6.33e-73	227.0	COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,42MDF@68525|delta/epsilon subdivisions,2YMNI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Pseudouridine synthase	sfhB	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
k59_1793050_1	1304883.KI912532_gene612	1.13e-96	293.0	COG1835@1|root,COG1835@2|Bacteria,1NSVZ@1224|Proteobacteria,2VKZ5@28216|Betaproteobacteria,2KW1B@206389|Rhodocyclales	206389|Rhodocyclales	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
k59_1320555_1	159087.Daro_3755	3.9e-32	124.0	COG2206@1|root,COG2206@2|Bacteria,1R3VR@1224|Proteobacteria,2VMY5@28216|Betaproteobacteria,2KVPZ@206389|Rhodocyclales	206389|Rhodocyclales	T	Domain of unknown function (DUF3391)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3391,HD_5
k59_1383436_1	1509403.GW12_21490	2.69e-37	131.0	COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,1RMK9@1236|Gammaproteobacteria,3NJ2J@468|Moraxellaceae	1236|Gammaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
k59_1383436_2	743720.Psefu_0641	3.88e-63	200.0	COG0088@1|root,COG0088@2|Bacteria,1MXPF@1224|Proteobacteria,1RNNK@1236|Gammaproteobacteria,1YWQQ@136845|Pseudomonas putida group	1236|Gammaproteobacteria	J	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome	rplD	GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003700,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008428,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030234,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032069,GO:0032074,GO:0032268,GO:0032269,GO:0032991,GO:0032993,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0065003,GO:0065007,GO:0065009,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:0098772,GO:0140110,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990904,GO:2000112,GO:2000113,GO:2001141	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
k59_29274_1	1286631.X805_41460	2.44e-12	68.2	COG2974@1|root,COG2974@2|Bacteria,1MXPR@1224|Proteobacteria,2VHD8@28216|Betaproteobacteria,1KJ5F@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	May be involved in recombination	rdgC	-	-	ko:K03554	-	-	-	-	ko00000,ko03400	-	-	-	RdgC
k59_209991_1	1304883.KI912532_gene90	3.15e-49	180.0	COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,2VHX1@28216|Betaproteobacteria,2KUPN@206389|Rhodocyclales	206389|Rhodocyclales	NU	COG3170 Tfp pilus assembly protein FimV	-	-	-	ko:K08086	-	-	-	-	ko00000	-	-	-	LysM
k59_506536_1	583345.Mmol_0215	1.69e-169	492.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,2VI1P@28216|Betaproteobacteria,2KMDT@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
k59_1566096_1	583345.Mmol_0382	2.54e-113	328.0	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,2VKTW@28216|Betaproteobacteria,2KKTE@206350|Nitrosomonadales	206350|Nitrosomonadales	L	TIGRFAM DNA repair protein RadC	-	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
k59_1566096_2	663610.JQKO01000009_gene488	3.7e-05	47.0	COG3174@1|root,COG3174@2|Bacteria,1NDBI@1224|Proteobacteria,2U0C9@28211|Alphaproteobacteria,3NAPD@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4010)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
k59_210005_1	572477.Alvin_2790	2.27e-43	146.0	COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,1RPA9@1236|Gammaproteobacteria,1WVVY@135613|Chromatiales	135613|Chromatiales	E	imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
k59_210005_2	90814.KL370891_gene88	3.96e-44	156.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,1RM7I@1236|Gammaproteobacteria,460AT@72273|Thiotrichales	72273|Thiotrichales	C	Belongs to the heme-copper respiratory oxidase family	-	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
k59_976465_1	717772.THIAE_01755	9.81e-40	150.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,461Z4@72273|Thiotrichales	72273|Thiotrichales	NT	helical bimodular (HBM) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,MCPsignal
k59_569323_1	435908.IDSA_02730	7.18e-18	80.9	COG0847@1|root,COG0847@2|Bacteria,1MUPK@1224|Proteobacteria,1RMMH@1236|Gammaproteobacteria,2QF6W@267893|Idiomarinaceae	1236|Gammaproteobacteria	L	Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis	rnt	GO:0000287,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0031123,GO:0034470,GO:0034641,GO:0034660,GO:0042780,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360	-	ko:K03683	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_T
k59_569323_2	1429851.X548_12920	1.57e-34	124.0	COG0537@1|root,COG0537@2|Bacteria,1MZVD@1224|Proteobacteria,1S9D9@1236|Gammaproteobacteria,1X77M@135614|Xanthomonadales	135614|Xanthomonadales	FG	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases	-	-	-	-	-	-	-	-	-	-	-	-	HIT
k59_569323_3	159087.Daro_3127	9e-47	159.0	COG0607@1|root,COG0607@2|Bacteria,1RDYR@1224|Proteobacteria,2VRSF@28216|Betaproteobacteria,2KXAZ@206389|Rhodocyclales	206389|Rhodocyclales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_1040592_1	509191.AEDB02000021_gene3120	1.42e-54	196.0	COG4251@1|root,COG5002@1|root,COG4251@2|Bacteria,COG5002@2|Bacteria,1VRP7@1239|Firmicutes,24YHW@186801|Clostridia,3WGBY@541000|Ruminococcaceae	186801|Clostridia	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_320136_2	1249480.B649_06650	1.57e-46	158.0	COG2199@1|root,COG2199@2|Bacteria,1Q4Z5@1224|Proteobacteria,4306K@68525|delta/epsilon subdivisions,2YRSF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	diguanylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_1448810_1	709032.Sulku_2447	2.48e-93	285.0	COG2885@1|root,COG2885@2|Bacteria,1QW22@1224|Proteobacteria,42NCQ@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	OmpA MotB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,OmpA
k59_1566133_1	709032.Sulku_1768	3.28e-127	364.0	COG0564@1|root,COG0564@2|Bacteria,1RDAG@1224|Proteobacteria,42SR2@68525|delta/epsilon subdivisions	1224|Proteobacteria	J	Pseudouridine synthase	Z012_05060	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23,5.4.99.24,5.4.99.28,5.4.99.29	ko:K06177,ko:K06179,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
k59_1040611_1	709032.Sulku_1265	1.93e-36	135.0	COG1449@1|root,COG1449@2|Bacteria,1Q9WP@1224|Proteobacteria,42M42@68525|delta/epsilon subdivisions,2YMAK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	2.4.1.25	ko:K22451	ko00500,map00500	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH57	-	DUF1925,DUF1926,Glyco_hydro_57
k59_1040611_2	709032.Sulku_1264	3.53e-48	169.0	COG1449@1|root,COG1449@2|Bacteria,1P2YJ@1224|Proteobacteria,42N8E@68525|delta/epsilon subdivisions,2YNF0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
k59_729184_1	159087.Daro_3010	9.95e-195	572.0	COG1305@1|root,COG4196@1|root,COG1305@2|Bacteria,COG4196@2|Bacteria,1MVAG@1224|Proteobacteria,2VKKZ@28216|Betaproteobacteria,2KV93@206389|Rhodocyclales	206389|Rhodocyclales	E	Putative amidoligase enzyme (DUF2126)	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,DUF2126,Transglut_core
k59_912744_1	604331.AUHY01000026_gene582	1.35e-11	67.4	COG1233@1|root,COG1233@2|Bacteria,1WIVY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
k59_912744_2	1537917.JU82_08090	7.9e-19	84.3	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,42M0C@68525|delta/epsilon subdivisions,2YM8W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
k59_1273182_1	1304883.KI912532_gene1760	7.49e-151	429.0	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,2VHS0@28216|Betaproteobacteria,2KUDJ@206389|Rhodocyclales	206389|Rhodocyclales	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
k59_569369_1	1249480.B649_07680	4.31e-13	67.8	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,42N01@68525|delta/epsilon subdivisions,2YMG2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
k59_569369_2	1537917.JU82_11165	1.48e-159	451.0	COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,42MJK@68525|delta/epsilon subdivisions,2YMV3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0400	LYTB
k59_1320642_1	1537917.JU82_07280	3.88e-39	140.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,42MXF@68525|delta/epsilon subdivisions,2YMJ8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Mur ligase middle domain	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
k59_1320642_2	709032.Sulku_0942	1.87e-42	145.0	COG0596@1|root,COG0596@2|Bacteria,1NH3R@1224|Proteobacteria,42R8Q@68525|delta/epsilon subdivisions,2YNWT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
k59_1153625_1	387093.SUN_0526	2.45e-159	463.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,42MMB@68525|delta/epsilon subdivisions,2YMVM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
k59_1448843_1	497321.C664_13434	2.2e-85	263.0	COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,2VKIS@28216|Betaproteobacteria,2KVRE@206389|Rhodocyclales	206389|Rhodocyclales	S	FAD-dependent pyridine	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
k59_1320647_1	1537917.JU82_03055	2.9e-47	167.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,42MDZ@68525|delta/epsilon subdivisions,2YMJR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaGprimase_HBD,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
k59_686065_2	1123399.AQVE01000009_gene3076	5.74e-10	62.8	COG2976@1|root,COG2976@2|Bacteria,1N117@1224|Proteobacteria,1S95P@1236|Gammaproteobacteria,46192@72273|Thiotrichales	72273|Thiotrichales	S	Tetratricopeptide repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_21
k59_154388_1	159087.Daro_0145	2.23e-98	298.0	COG0745@1|root,COG4783@1|root,COG0745@2|Bacteria,COG4783@2|Bacteria,1QWFU@1224|Proteobacteria,2WGYB@28216|Betaproteobacteria,2KZWT@206389|Rhodocyclales	206389|Rhodocyclales	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_1320653_1	709032.Sulku_1005	4.66e-122	355.0	COG0694@1|root,COG0822@1|root,COG0694@2|Bacteria,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,42MT6@68525|delta/epsilon subdivisions,2YMXY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CO	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins	-	-	-	ko:K13819	-	-	-	-	ko00000	-	-	-	Fer2_BFD,NifU,NifU_N
k59_732607_1	1304883.KI912532_gene2320	5.58e-51	171.0	COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,2VK57@28216|Betaproteobacteria,2KV84@206389|Rhodocyclales	206389|Rhodocyclales	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroA	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
k59_732607_2	159087.Daro_1965	1.14e-37	140.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,2VI7M@28216|Betaproteobacteria,2KVGD@206389|Rhodocyclales	206389|Rhodocyclales	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_1569764_1	666681.M301_0184	1.37e-57	178.0	COG2924@1|root,COG2924@2|Bacteria,1MZ2V@1224|Proteobacteria,2VTYU@28216|Betaproteobacteria,2KN0U@206350|Nitrosomonadales	206350|Nitrosomonadales	CO	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Iron_traffic
k59_1569764_2	583345.Mmol_2199	1.12e-29	109.0	COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,2VU5Y@28216|Betaproteobacteria,2KMXB@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Recycling of diacylglycerol produced during the turnover of membrane phospholipid	-	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
k59_90255_1	1249480.B649_00005	7.59e-67	215.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,42MA0@68525|delta/epsilon subdivisions,2YM88@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
k59_980476_1	1249480.B649_00340	1.66e-14	72.0	COG1293@1|root,COG1293@2|Bacteria,1R54S@1224|Proteobacteria,42MYG@68525|delta/epsilon subdivisions,2YT8X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	RNA-binding protein homologous to eukaryotic snRNP	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
k59_980476_2	1249480.B649_00335	2.43e-192	547.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42Q5F@68525|delta/epsilon subdivisions,2YPMR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	Cache_3-Cache_2,MCPsignal
k59_446534_1	1249480.B649_10615	1.29e-96	293.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42NES@68525|delta/epsilon subdivisions,2YNJ6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	COG1459 Type II secretory pathway, component PulF	-	-	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
k59_32490_1	1123517.JOMR01000001_gene829	1.92e-31	119.0	COG0484@1|root,COG0484@2|Bacteria,1NQPP@1224|Proteobacteria,1SMXQ@1236|Gammaproteobacteria,46250@72273|Thiotrichales	72273|Thiotrichales	O	DnaJ molecular chaperone homology domain	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
k59_32490_2	575788.VS_1073	8.47e-31	112.0	COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,1S8Z7@1236|Gammaproteobacteria,1XXDA@135623|Vibrionales	135623|Vibrionales	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
k59_213683_1	395494.Galf_2166	2.65e-70	225.0	COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,2VI1Y@28216|Betaproteobacteria,44VFZ@713636|Nitrosomonadales	28216|Betaproteobacteria	O	CAAX prenyl protease N-terminal, five membrane helices	htpX_2	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
k59_1157512_1	1123392.AQWL01000002_gene1772	1.83e-23	90.9	COG2010@1|root,COG2010@2|Bacteria,1N73U@1224|Proteobacteria,2VTXS@28216|Betaproteobacteria,1KTE6@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K19344	-	-	-	-	ko00000	-	-	-	Cytochrome_CBB3
k59_1157512_2	159087.Daro_3270	4.13e-57	187.0	COG3391@1|root,COG3391@2|Bacteria,1QD5Q@1224|Proteobacteria,2VH1W@28216|Betaproteobacteria,2KVXA@206389|Rhodocyclales	206389|Rhodocyclales	S	cytochrome d1 heme	nirF	-	-	ko:K19345	-	-	-	-	ko00000	-	-	-	Cytochrom_D1
k59_1157518_1	868131.MSWAN_2217	6.84e-49	164.0	COG0596@1|root,arCOG01648@2157|Archaea,2XVXV@28890|Euryarchaeota,23PSC@183925|Methanobacteria	183925|Methanobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
k59_213737_1	1304883.KI912532_gene2638	2.15e-73	233.0	COG2404@1|root,COG2404@2|Bacteria,1MXEH@1224|Proteobacteria,2VKWK@28216|Betaproteobacteria,2KX23@206389|Rhodocyclales	206389|Rhodocyclales	S	Phosphoesterase DHHA1	-	-	-	-	-	-	-	-	-	-	-	-	DHHA1
k59_690188_1	1168034.FH5T_12545	1.65e-36	132.0	COG2815@1|root,COG2815@2|Bacteria,4NSUI@976|Bacteroidetes,2FPS4@200643|Bacteroidia	976|Bacteroidetes	S	PASTA domain protein	spk1	-	2.7.11.1,6.3.2.4	ko:K01921,ko:K08884,ko:K12132	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01001,ko01011	-	-	-	PASTA
k59_1324575_1	1537917.JU82_05240	2.07e-129	381.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2YMB5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	abc transporter atp-binding protein	yheS	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
k59_1863379_1	1121035.AUCH01000021_gene2730	2.36e-56	197.0	COG0835@1|root,COG0835@2|Bacteria,1QVCF@1224|Proteobacteria,2VK5W@28216|Betaproteobacteria,2KVUN@206389|Rhodocyclales	206389|Rhodocyclales	NT	Two component signalling adaptor domain	-	-	-	-	-	-	-	-	-	-	-	-	CheW
k59_1621445_1	1249480.B649_01820	3.81e-81	262.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YMHP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3
k59_270189_1	709032.Sulku_0600	8.41e-185	521.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,42NGU@68525|delta/epsilon subdivisions,2YMCD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN2	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k59_32607_1	1537917.JU82_04495	9.31e-88	270.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,42M48@68525|delta/epsilon subdivisions,2YMM2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
k59_1131334_1	1304883.KI912532_gene1017	2e-93	281.0	COG1703@1|root,COG1703@2|Bacteria,1MVI0@1224|Proteobacteria,2VIRF@28216|Betaproteobacteria,2KVDF@206389|Rhodocyclales	206389|Rhodocyclales	E	periplasmic protein kinase ArgK and related GTPases of G3E family	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
k59_1657656_1	1165841.SULAR_07655	4.54e-40	144.0	COG0642@1|root,COG0642@2|Bacteria,1RGPU@1224|Proteobacteria,42RPY@68525|delta/epsilon subdivisions,2YPD9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG0642 Signal transduction histidine kinase	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_1424689_1	1537917.JU82_01240	4.96e-99	305.0	COG0204@1|root,COG0477@1|root,COG0204@2|Bacteria,COG2814@2|Bacteria,1MWDY@1224|Proteobacteria,43BJD@68525|delta/epsilon subdivisions,2YNEB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	2-acylglycerophosphoethanolamine acyltransferase	aas	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
k59_1187670_1	1249480.B649_09645	1.07e-85	266.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,42NDE@68525|delta/epsilon subdivisions,2YMNM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Hydrogenase, large subunit	hupL	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
k59_1304055_1	1121035.AUCH01000021_gene2730	3.81e-74	247.0	COG0835@1|root,COG0835@2|Bacteria,1QVCF@1224|Proteobacteria,2VK5W@28216|Betaproteobacteria,2KVUN@206389|Rhodocyclales	206389|Rhodocyclales	NT	Two component signalling adaptor domain	-	-	-	-	-	-	-	-	-	-	-	-	CheW
k59_1598713_1	1121035.AUCH01000003_gene1219	2.28e-77	263.0	COG0642@1|root,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,2VIXT@28216|Betaproteobacteria,2KUH6@206389|Rhodocyclales	206389|Rhodocyclales	T	Histidine kinase	-	-	2.7.13.3	ko:K20975	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Response_reg
k59_70447_1	709032.Sulku_2085	4.01e-19	82.8	2BR51@1|root,32K31@2|Bacteria,1Q8HX@1224|Proteobacteria,433KM@68525|delta/epsilon subdivisions,2YSI4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_836973_1	1249480.B649_09290	6.94e-34	125.0	2CHQX@1|root,33W06@2|Bacteria,1NWMC@1224|Proteobacteria,42V4N@68525|delta/epsilon subdivisions	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_485410_1	159087.Daro_3904	2.65e-83	268.0	COG0659@1|root,COG0664@1|root,COG0659@2|Bacteria,COG0664@2|Bacteria,1MVWV@1224|Proteobacteria,2VN25@28216|Betaproteobacteria,2KXUF@206389|Rhodocyclales	206389|Rhodocyclales	P	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp,cNMP_binding
k59_545215_1	159087.Daro_0716	2.74e-95	284.0	COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,2VHGS@28216|Betaproteobacteria,2KUZH@206389|Rhodocyclales	206389|Rhodocyclales	C	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
k59_662389_1	159087.Daro_1467	6.11e-110	322.0	COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,2VJAP@28216|Betaproteobacteria,2KVIW@206389|Rhodocyclales	206389|Rhodocyclales	C	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3	-	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
k59_1542702_1	1249480.B649_05060	2.7e-38	141.0	COG0840@1|root,COG0840@2|Bacteria,1R486@1224|Proteobacteria,42Q5Y@68525|delta/epsilon subdivisions,2YNT8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	CZB,MCPsignal
k59_1304096_1	331678.Cphamn1_1252	5.34e-54	174.0	COG3335@1|root,COG3335@2|Bacteria	2|Bacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
k59_485466_1	76114.ebA2143	3.47e-20	90.5	COG3203@1|root,COG3203@2|Bacteria,1RB94@1224|Proteobacteria,2VQW4@28216|Betaproteobacteria,2M006@206389|Rhodocyclales	206389|Rhodocyclales	M	Gram-negative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
k59_954690_1	159087.Daro_0598	3.97e-115	338.0	COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,2VH1J@28216|Betaproteobacteria,2KURQ@206389|Rhodocyclales	206389|Rhodocyclales	C	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k59_954690_2	1304883.KI912532_gene1401	2.79e-12	63.2	COG0783@1|root,COG0783@2|Bacteria,1RAC5@1224|Proteobacteria,2VHJI@28216|Betaproteobacteria,2KW76@206389|Rhodocyclales	206389|Rhodocyclales	P	Belongs to the Dps family	-	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
k59_1836353_1	1249480.B649_08110	3.89e-131	386.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,42NKZ@68525|delta/epsilon subdivisions,2YMT9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	RND efflux system, outer membrane lipoprotein	cmeC	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
k59_1657721_1	1537917.JU82_07000	2.28e-149	436.0	COG1766@1|root,COG1766@2|Bacteria,1MUQR@1224|Proteobacteria,42N04@68525|delta/epsilon subdivisions,2YMF6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	The M ring may be actively involved in energy transduction	fliF	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
k59_1187723_1	1304883.KI912532_gene730	7.28e-93	281.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,2VIS0@28216|Betaproteobacteria,2KUN7@206389|Rhodocyclales	206389|Rhodocyclales	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
k59_954702_1	709032.Sulku_1277	1.65e-37	140.0	COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,1QTS5@1224|Proteobacteria,42MPY@68525|delta/epsilon subdivisions,2YMV7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	phosphate acetyltransferase	pta	-	2.3.1.8	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,DRTGG,PTA_PTB
k59_1598773_1	159087.Daro_1972	3.48e-61	202.0	COG3174@1|root,COG3174@2|Bacteria,1NDBI@1224|Proteobacteria,2VJ4P@28216|Betaproteobacteria,2KUDC@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of unknown function (DUF4010)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
k59_1304125_1	326298.Suden_0867	1.36e-08	54.7	COG1765@1|root,COG1765@2|Bacteria,1NKRY@1224|Proteobacteria,42UP7@68525|delta/epsilon subdivisions,2YQ0P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	redox protein regulator of disulfide bond formation	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
k59_1304125_2	1380391.JIAS01000006_gene2532	7.96e-16	81.3	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,2TRWK@28211|Alphaproteobacteria,2JQVC@204441|Rhodospirillales	204441|Rhodospirillales	P	Acts as a magnesium transporter	-	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
k59_188810_2	709032.Sulku_1573	2.99e-59	191.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,42MYJ@68525|delta/epsilon subdivisions,2YN0I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS
k59_1598787_1	1165841.SULAR_07018	1.04e-77	239.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,42NMR@68525|delta/epsilon subdivisions,2YN8M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k59_1249548_1	118005.AWNK01000012_gene35	1.79e-28	117.0	COG2206@1|root,COG2206@2|Bacteria	2|Bacteria	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
k59_1424818_1	717773.Thicy_0760	3.75e-79	254.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,1RNGV@1236|Gammaproteobacteria,45ZPV@72273|Thiotrichales	72273|Thiotrichales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
k59_601765_1	159087.Daro_3993	2.8e-160	450.0	COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,2VHF8@28216|Betaproteobacteria,2KV1K@206389|Rhodocyclales	206389|Rhodocyclales	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
k59_601765_2	159087.Daro_3992	2.11e-52	170.0	COG2386@1|root,COG2386@2|Bacteria,1NJB0@1224|Proteobacteria,2VNPU@28216|Betaproteobacteria,2KW4C@206389|Rhodocyclales	206389|Rhodocyclales	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmB	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
k59_70534_2	709032.Sulku_1240	4.72e-38	140.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,43AD6@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k59_249094_1	156889.Mmc1_0232	2.69e-30	134.0	COG0784@1|root,COG3447@1|root,COG4191@1|root,COG5002@1|root,COG0784@2|Bacteria,COG3447@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
k59_1657786_1	709032.Sulku_0715	1.63e-97	295.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42NES@68525|delta/epsilon subdivisions,2YMT3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Type II secretion system	ctsF	-	-	ko:K02455,ko:K12278	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
k59_1598836_1	1249480.B649_04850	1.32e-69	233.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,42MD4@68525|delta/epsilon subdivisions,2YNMI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	PFAM Helicase conserved C-terminal domain	hrpB	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
k59_70560_1	1123518.ARWI01000001_gene2032	4.57e-46	162.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RNV0@1236|Gammaproteobacteria,4607Z@72273|Thiotrichales	72273|Thiotrichales	NU	type II secretion	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
k59_1249612_1	1249480.B649_11210	6.01e-128	375.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,42MAI@68525|delta/epsilon subdivisions,2YMCW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	iIT341.HP0476	tRNA-synt_1c
k59_601821_1	236097.ADG881_1071	2.44e-91	283.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,1RN7V@1236|Gammaproteobacteria,1XHR4@135619|Oceanospirillales	135619|Oceanospirillales	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
k59_1716269_1	1198232.CYCME_0174	7.71e-51	170.0	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,1RQZP@1236|Gammaproteobacteria,4602G@72273|Thiotrichales	72273|Thiotrichales	M	mechanosensitive ion channel	-	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
k59_1017695_1	1249480.B649_00610	1.89e-65	202.0	COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,43BC4@68525|delta/epsilon subdivisions,2YMGN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
k59_426465_2	391735.Veis_5024	1.17e-71	232.0	COG3704@1|root,COG3704@2|Bacteria,1PZBS@1224|Proteobacteria,2WC79@28216|Betaproteobacteria,4AIY1@80864|Comamonadaceae	28216|Betaproteobacteria	U	PFAM TrbL VirB6 plasmid conjugal transfer protein	-	-	-	ko:K03201	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	TrbL
k59_1545386_1	709032.Sulku_2476	7.58e-97	297.0	COG3437@1|root,COG4191@1|root,COG3437@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43DAR@68525|delta/epsilon subdivisions,2YTHT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HD
k59_777944_1	159087.Daro_4176	1.15e-60	191.0	COG2834@1|root,COG2834@2|Bacteria,1RHYN@1224|Proteobacteria,2VSXY@28216|Betaproteobacteria,2KWSE@206389|Rhodocyclales	206389|Rhodocyclales	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	LolA
k59_777944_2	159087.Daro_4177	1.06e-44	160.0	COG4258@1|root,COG4258@2|Bacteria,1MU1E@1224|Proteobacteria,2VHXY@28216|Betaproteobacteria,2KVVT@206389|Rhodocyclales	206389|Rhodocyclales	S	MMPL family	-	-	-	-	-	-	-	-	-	-	-	-	MMPL
k59_1134023_2	709032.Sulku_2336	2.99e-46	163.0	COG2194@1|root,COG2194@2|Bacteria,1MWS7@1224|Proteobacteria,42MI1@68525|delta/epsilon subdivisions,2YMPQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Sulfatase	eptA	-	2.7.8.43	ko:K03760	ko01503,map01503	M00722	R11555,R11556,R11557	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DUF1705,Sulfatase
k59_1600871_2	709032.Sulku_1816	1.7e-103	301.0	COG1881@1|root,COG1881@2|Bacteria,1N0Y4@1224|Proteobacteria,42RJP@68525|delta/epsilon subdivisions,2YP82@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COG1881 Phospholipid-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
k59_1600871_3	1537917.JU82_08560	5.11e-63	199.0	COG1741@1|root,COG1741@2|Bacteria,1MVSW@1224|Proteobacteria,42T87@68525|delta/epsilon subdivisions,2YMZ0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
k59_665184_1	1537917.JU82_02225	1.2e-93	284.0	2C76X@1|root,2ZM1W@2|Bacteria,1P5JD@1224|Proteobacteria,42P9T@68525|delta/epsilon subdivisions,2YMRC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_548042_2	1537917.JU82_01625	8.79e-161	454.0	COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,42N3J@68525|delta/epsilon subdivisions,2YMKA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
k59_548042_3	709032.Sulku_2254	1.47e-182	513.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,42MKD@68525|delta/epsilon subdivisions,2YMRD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k59_366863_1	1537917.JU82_09120	1.03e-146	443.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,42MGK@68525|delta/epsilon subdivisions,2YMHU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_548043_2	305900.GV64_18870	1.01e-05	47.0	COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,1SC8A@1236|Gammaproteobacteria,1XM4S@135619|Oceanospirillales	135619|Oceanospirillales	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
k59_366864_2	1249480.B649_03485	5.59e-14	69.3	COG3176@1|root,COG3176@2|Bacteria,1R1JY@1224|Proteobacteria,43DAB@68525|delta/epsilon subdivisions,2YSQN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5
k59_1252302_1	159087.Daro_0316	2.18e-41	150.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,2VI3Q@28216|Betaproteobacteria,2KUP0@206389|Rhodocyclales	206389|Rhodocyclales	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_896965_1	159087.Daro_0482	2.78e-51	173.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,2VITN@28216|Betaproteobacteria,2KUZ2@206389|Rhodocyclales	206389|Rhodocyclales	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
k59_1718348_1	1316936.K678_10681	1.77e-22	103.0	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2TZDS@28211|Alphaproteobacteria,2JZ03@204441|Rhodospirillales	204441|Rhodospirillales	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_9,Response_reg
k59_1134072_1	1167006.UWK_00511	4.2e-28	116.0	COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,1QTS5@1224|Proteobacteria,42MPY@68525|delta/epsilon subdivisions,2WJ2V@28221|Deltaproteobacteria,2MJGM@213118|Desulfobacterales	28221|Deltaproteobacteria	C	belongs to the CobB CobQ family	pta	-	2.3.1.8	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1035	AAA_26,DRTGG,PTA_PTB
k59_135802_1	1123518.ARWI01000001_gene2258	1.29e-152	439.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,1RMUD@1236|Gammaproteobacteria,45ZSD@72273|Thiotrichales	72273|Thiotrichales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
k59_665231_1	1537917.JU82_00725	1.21e-19	88.2	COG3228@1|root,COG3228@2|Bacteria,1RAHF@1224|Proteobacteria,42QKQ@68525|delta/epsilon subdivisions,2YMYQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the MtfA family	-	-	-	ko:K09933	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_M90
k59_665231_2	1249480.B649_00030	1.63e-23	98.6	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria	1224|Proteobacteria	P	Receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_135813_1	395494.Galf_1726	6.93e-132	379.0	COG2171@1|root,COG2171@2|Bacteria,1MU0Y@1224|Proteobacteria,2VHUX@28216|Betaproteobacteria,44VFW@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Belongs to the transferase hexapeptide repeat family	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
k59_190973_1	1304883.KI912532_gene934	4.4e-108	328.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,2VIGG@28216|Betaproteobacteria,2KUAA@206389|Rhodocyclales	206389|Rhodocyclales	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
k59_1073721_1	522306.CAP2UW1_3144	2.14e-35	124.0	2E80B@1|root,332EM@2|Bacteria,1N7PZ@1224|Proteobacteria,2VVZX@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1073721_2	857087.Metme_1146	6.44e-30	115.0	COG4782@1|root,COG4782@2|Bacteria,1MXVC@1224|Proteobacteria,1RYK7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Alpha/beta hydrolase of unknown function (DUF900)	-	-	-	-	-	-	-	-	-	-	-	-	DUF900
k59_307964_1	1123518.ARWI01000001_gene1163	6.83e-61	209.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,1RNZ2@1236|Gammaproteobacteria,4608B@72273|Thiotrichales	72273|Thiotrichales	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
k59_1545540_1	1157708.KB907450_gene5539	6.86e-48	169.0	COG1797@1|root,COG1797@2|Bacteria,1MV7Z@1224|Proteobacteria,2VI93@28216|Betaproteobacteria,4AA2D@80864|Comamonadaceae	28216|Betaproteobacteria	H	Cobyrinic acid ac-diamide synthase	cobB	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	CbiA,GATase_3
k59_665319_1	709032.Sulku_1746	4.97e-152	439.0	COG0457@1|root,COG0457@2|Bacteria,1Q55C@1224|Proteobacteria,42RCA@68525|delta/epsilon subdivisions,2YND3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	PPR
k59_251297_1	159087.Daro_3687	9.99e-14	69.7	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,2VJKV@28216|Betaproteobacteria,2KV7M@206389|Rhodocyclales	206389|Rhodocyclales	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k59_251297_2	159087.Daro_3684	8.71e-116	337.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,2VP72@28216|Betaproteobacteria,2KW1H@206389|Rhodocyclales	206389|Rhodocyclales	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
k59_716857_1	159087.Daro_3405	1.21e-210	597.0	COG1450@1|root,COG1450@2|Bacteria,1MVNC@1224|Proteobacteria,2VMT1@28216|Betaproteobacteria,2KUZ5@206389|Rhodocyclales	206389|Rhodocyclales	NU	Type II and III secretion system protein	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N_2
k59_1366150_1	1537917.JU82_09715	6.71e-108	339.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,42MWW@68525|delta/epsilon subdivisions,2YMMH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_716858_1	159087.Daro_0878	2.57e-146	421.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,2KVW1@206389|Rhodocyclales	206389|Rhodocyclales	JKL	DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k59_366961_1	159087.Daro_3747	1.37e-29	110.0	COG0791@1|root,COG0791@2|Bacteria,1RJ3U@1224|Proteobacteria,2VSD3@28216|Betaproteobacteria,2KWTG@206389|Rhodocyclales	206389|Rhodocyclales	M	NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
k59_366961_2	999541.bgla_2g04900	4.03e-16	78.6	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VHGR@28216|Betaproteobacteria,1K02G@119060|Burkholderiaceae	28216|Betaproteobacteria	C	belongs to the aldehyde dehydrogenase family	gabD	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_778069_1	1502770.JQMG01000001_gene728	1.18e-120	347.0	COG0461@1|root,COG0461@2|Bacteria,1MW6F@1224|Proteobacteria,2VH9U@28216|Betaproteobacteria,2KM5T@206350|Nitrosomonadales	206350|Nitrosomonadales	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
k59_665337_1	159087.Daro_3383	9.2e-104	310.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,2VHFU@28216|Betaproteobacteria,2KV26@206389|Rhodocyclales	206389|Rhodocyclales	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_135911_1	326298.Suden_1432	4.85e-67	222.0	COG0068@1|root,COG0068@2|Bacteria,1NS2D@1224|Proteobacteria,42RUP@68525|delta/epsilon subdivisions,2YP7H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide	hydE	-	-	-	-	-	-	-	-	-	-	-	-
k59_426619_1	748247.AZKH_3346	1.39e-92	278.0	COG0834@1|root,COG0834@2|Bacteria,1MVT6@1224|Proteobacteria,2VH1B@28216|Betaproteobacteria,2KV7S@206389|Rhodocyclales	206389|Rhodocyclales	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
k59_1427746_1	1177154.Y5S_01806	2.05e-36	137.0	COG0380@1|root,COG0561@1|root,COG0380@2|Bacteria,COG0561@2|Bacteria,1MUIY@1224|Proteobacteria,1RNG7@1236|Gammaproteobacteria,1XN6H@135619|Oceanospirillales	135619|Oceanospirillales	G	Glycosyltransferase family 20	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_20,S6PP
k59_1134205_1	159087.Daro_0711	3.61e-81	263.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,1MU08@1224|Proteobacteria,2VJSM@28216|Betaproteobacteria,2KV1V@206389|Rhodocyclales	206389|Rhodocyclales	P	cation transport ATPase	ccoI	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
k59_488313_1	497964.CfE428DRAFT_4957	1.21e-34	135.0	COG4191@1|root,COG4191@2|Bacteria,46TN7@74201|Verrucomicrobia	74201|Verrucomicrobia	T	SMART PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg
k59_161023_1	1537917.JU82_11280	7.5e-134	395.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,42MPK@68525|delta/epsilon subdivisions,2YMFX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,SurA_N_3
k59_806315_1	946483.Cenrod_0093	5.9e-42	138.0	COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,2VU1B@28216|Betaproteobacteria,4AEX1@80864|Comamonadaceae	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
k59_806315_2	1538295.JY96_17400	3.48e-29	104.0	COG0267@1|root,COG0267@2|Bacteria,1N6QV@1224|Proteobacteria,2VVW8@28216|Betaproteobacteria,1KMIZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
k59_1799535_1	663321.REG_1909	1.08e-13	69.7	COG0283@1|root,COG0283@2|Bacteria,1MUUD@1224|Proteobacteria,1RNKT@1236|Gammaproteobacteria,282QS@191675|unclassified Enterobacteriaceae	1236|Gammaproteobacteria	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0015939,GO:0015940,GO:0015949,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iPC815.YPO1391,iSDY_1059.SDY_2348	Cytidylate_kin
k59_1799535_2	1207076.ALAT01000099_gene2497	4.92e-65	219.0	COG0128@1|root,COG0287@1|root,COG0128@2|Bacteria,COG0287@2|Bacteria,1MWMK@1224|Proteobacteria,1RQ8U@1236|Gammaproteobacteria,1Z1RM@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	1.3.1.12,1.3.1.43,2.5.1.19	ko:K00210,ko:K00220,ko:K00800	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00022,M00025,M00040	R00732,R01728,R03460	RC00125,RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase,PDH
k59_1160884_1	1123326.JFBL01000013_gene317	9.75e-26	110.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,42MIH@68525|delta/epsilon subdivisions,2YRAS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
k59_513559_1	519989.ECTPHS_00480	7.51e-39	146.0	COG0305@1|root,COG1372@1|root,COG0305@2|Bacteria,COG1372@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,1WW1X@135613|Chromatiales	135613|Chromatiales	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	-	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3
k59_513559_2	1453501.JELR01000002_gene883	1.1e-44	150.0	COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,1S3WS@1236|Gammaproteobacteria,466HW@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
k59_273118_1	1173025.GEI7407_3053	4.25e-27	115.0	COG2199@1|root,COG4252@1|root,COG2199@2|Bacteria,COG4252@2|Bacteria,1G17N@1117|Cyanobacteria,1H85X@1150|Oscillatoriales	1117|Cyanobacteria	T	Diguanylate cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,GGDEF,PAS,PAS_4
k59_1280853_1	1249480.B649_04950	3.76e-38	139.0	COG3087@1|root,COG3147@1|root,COG3087@2|Bacteria,COG3147@2|Bacteria,1MYFG@1224|Proteobacteria,42X9Q@68525|delta/epsilon subdivisions,2YQPX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Sporulation related domain	-	-	-	ko:K03749	-	-	-	-	ko00000	-	-	-	SPOR
k59_1280853_2	1537917.JU82_05600	4.6e-81	254.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,42MXN@68525|delta/epsilon subdivisions,2YN93@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EH	anthranilate synthase component	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP1282	Anth_synt_I_N,Chorismate_bind
k59_736011_1	653948.CCA23580	3.77e-14	73.2	COG0564@1|root,KOG1919@2759|Eukaryota	2759|Eukaryota	J	pseudouridine synthase activity	-	-	-	-	-	-	-	-	-	-	-	-	PseudoU_synth_2
k59_736011_2	1121035.AUCH01000006_gene713	1.51e-90	280.0	COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,2VHA8@28216|Betaproteobacteria,2KUVM@206389|Rhodocyclales	206389|Rhodocyclales	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
k59_1280854_1	1249480.B649_00575	1.67e-80	239.0	COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,42TJK@68525|delta/epsilon subdivisions,2YQ4A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
k59_1214059_1	859657.RPSI07_mp0460	1.2e-15	79.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,2VN6Q@28216|Betaproteobacteria,1K38J@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	cusB	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
k59_1214059_2	401053.AciPR4_2130	4.99e-13	70.9	COG1538@1|root,COG1538@2|Bacteria,3Y66Y@57723|Acidobacteria,2JKJ4@204432|Acidobacteriia	204432|Acidobacteriia	MU	Outer membrane efflux protein	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
k59_631434_2	159087.Daro_3538	2.15e-20	87.0	COG1451@1|root,COG1451@2|Bacteria,1MXZU@1224|Proteobacteria,2VNC5@28216|Betaproteobacteria,2KWES@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
k59_388417_1	709032.Sulku_2534	1.85e-39	148.0	COG3164@1|root,COG3164@2|Bacteria,1QUYX@1224|Proteobacteria,43CES@68525|delta/epsilon subdivisions,2YTC9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
k59_388417_2	709032.Sulku_2532	1.18e-150	433.0	COG2855@1|root,COG2855@2|Bacteria,1MVIP@1224|Proteobacteria,42P59@68525|delta/epsilon subdivisions,2YMPJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the UPF0324 family	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
k59_1625619_1	1165841.SULAR_03862	1.02e-62	207.0	COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,42YPF@68525|delta/epsilon subdivisions,2YRMB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Uncharacterized ACR, YdiU/UPF0061 family	-	-	-	-	-	-	-	-	-	-	-	-	UPF0061
k59_920832_1	709032.Sulku_0131	3.85e-81	256.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,42PK7@68525|delta/epsilon subdivisions,2YMS5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Amidase	-	-	3.5.1.54	ko:K01457	ko00220,ko00791,ko01100,ko01120,map00220,map00791,map01100,map01120	-	R00005	RC02756	ko00000,ko00001,ko01000	-	-	-	Amidase
k59_1329246_1	1165841.SULAR_07203	4.39e-59	191.0	COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,42MBW@68525|delta/epsilon subdivisions,2YMVQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	ribonuclease BN	rbn	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
k59_985242_1	1249480.B649_07315	5.62e-47	165.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42NK1@68525|delta/epsilon subdivisions,2YMHN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the AAA ATPase family	ftsH1	-	-	-	-	-	-	-	-	-	-	-	AAA,Peptidase_M41
k59_985242_2	1249480.B649_07320	1.02e-19	87.8	COG0621@1|root,COG0621@2|Bacteria,1MUCS@1224|Proteobacteria,42MN1@68525|delta/epsilon subdivisions,2YN0D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	MiaB-like tRNA modifying enzyme	yqeV	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,UPF0004
k59_1625692_1	159087.Daro_0202	1.46e-45	162.0	COG1366@1|root,COG1366@2|Bacteria,1R08G@1224|Proteobacteria,2VIGK@28216|Betaproteobacteria,2KVYW@206389|Rhodocyclales	206389|Rhodocyclales	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	-	-	-	-	-	-	-	-	-	STAS_2
k59_1573937_1	1502770.JQMG01000001_gene1351	5.3e-08	52.8	COG3028@1|root,COG3028@2|Bacteria,1MZ4R@1224|Proteobacteria,2VSGZ@28216|Betaproteobacteria,2KMRU@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Belongs to the UPF0307 family	-	-	-	ko:K09889	-	-	-	-	ko00000,ko03009	-	-	-	DUF615
k59_1573937_2	1502770.JQMG01000001_gene1352	8.32e-59	194.0	COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,2VHJ4@28216|Betaproteobacteria,2KKFE@206350|Nitrosomonadales	206350|Nitrosomonadales	S	PFAM peptidase U62 modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
k59_1625713_1	709032.Sulku_0529	2.48e-156	457.0	COG0726@1|root,COG1649@1|root,COG0726@2|Bacteria,COG1649@2|Bacteria,1MWR2@1224|Proteobacteria,43AG1@68525|delta/epsilon subdivisions,2YT1V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Hypothetical glycosyl hydrolase family 13	-	-	-	ko:K11931	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000	-	-	-	GHL13,Polysacc_deac_1
k59_36530_1	266264.Rmet_4702	8.14e-113	337.0	COG2132@1|root,COG2132@2|Bacteria,1R89G@1224|Proteobacteria,2VH5I@28216|Betaproteobacteria,1K2NB@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_3
k59_217677_1	177439.DPPB05	1.46e-232	648.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,42RS8@68525|delta/epsilon subdivisions,2X5QK@28221|Deltaproteobacteria,2MMIZ@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
k59_93355_1	946483.Cenrod_0851	9.01e-35	136.0	COG2703@1|root,COG5001@1|root,COG2703@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,4AD7J@80864|Comamonadaceae	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	CZB,EAL,GAF,GAF_2,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_631515_1	1304883.KI912532_gene1703	2.49e-107	312.0	COG0235@1|root,COG0235@2|Bacteria,1MW7B@1224|Proteobacteria,2VQBC@28216|Betaproteobacteria,2KW2V@206389|Rhodocyclales	206389|Rhodocyclales	G	Class II aldolase adducin family protein	fucA	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
k59_1214165_1	159087.Daro_2832	1.49e-80	260.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,2VHKP@28216|Betaproteobacteria,2KVQM@206389|Rhodocyclales	206389|Rhodocyclales	S	DNA internalization-related competence protein ComEC Rec2	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
k59_1507421_1	1537917.JU82_06975	1.15e-53	179.0	COG0795@1|root,COG0795@2|Bacteria,1PXEK@1224|Proteobacteria,42MVG@68525|delta/epsilon subdivisions,2YN6F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	permease	-	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_1743974_1	1537917.JU82_09775	8.34e-137	405.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	mmoS	-	-	ko:K20972	ko02025,map02025	-	-	-	ko00000,ko00001,ko01001,ko02022	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,CHASE5,HATPase_c,HisKA,Hpt,Response_reg
k59_1280957_1	1537917.JU82_08405	5.76e-127	364.0	COG3751@1|root,COG3751@2|Bacteria,1Q4MK@1224|Proteobacteria,42ZFP@68525|delta/epsilon subdivisions,2YRNS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Prolyl 4-hydroxylase alpha subunit homologues.	-	-	-	ko:K07394	-	-	-	-	ko00000	-	-	-	2OG-FeII_Oxy_3
k59_273280_1	519989.ECTPHS_04708	9.15e-80	252.0	COG1157@1|root,COG1157@2|Bacteria,1MUH6@1224|Proteobacteria,1RM9W@1236|Gammaproteobacteria,1WVYU@135613|Chromatiales	135613|Chromatiales	N	ATPase FliI YscN family	-	-	3.6.3.14	ko:K02412	ko02040,map02040	-	-	-	ko00000,ko00001,ko01000,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	ATP-synt_ab
k59_1048131_1	709032.Sulku_2066	1.33e-109	320.0	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,43ADP@68525|delta/epsilon subdivisions,2YT26@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_1214237_1	709032.Sulku_1959	7.84e-60	197.0	COG3437@1|root,COG3437@2|Bacteria,1QYD6@1224|Proteobacteria,43CBH@68525|delta/epsilon subdivisions,2YTB6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	cheY-homologous receiver domain	-	-	3.1.1.61,3.5.1.44	ko:K03412,ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	Response_reg
k59_1214237_2	1227352.C173_25441	5.04e-12	66.6	COG0745@1|root,COG0784@1|root,COG5002@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG5002@2|Bacteria,1UIHJ@1239|Firmicutes,4ISI2@91061|Bacilli,2774Z@186822|Paenibacillaceae	91061|Bacilli	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,GAF_2,HATPase_c,HisKA,His_kinase,Response_reg
k59_93438_1	159087.Daro_2440	2.43e-87	268.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,2VJ7A@28216|Betaproteobacteria,2KUVI@206389|Rhodocyclales	206389|Rhodocyclales	M	UDP binding domain	-	-	-	ko:K02474	ko00520,map00520	-	R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_1098108_1	402626.Rpic_1475	1.35e-58	190.0	COG0834@1|root,COG0834@2|Bacteria,1MV5D@1224|Proteobacteria,2VHFS@28216|Betaproteobacteria,1K5X5@119060|Burkholderiaceae	28216|Betaproteobacteria	ET	PFAM extracellular solute-binding protein, family 3	gltI	-	-	ko:K10001	ko02010,ko02020,map02010,map02020	M00230	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.19,3.A.1.3.4	-	-	SBP_bac_3
k59_93447_1	1274524.BSONL12_06073	2.48e-48	170.0	COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4H9YP@91061|Bacilli,1ZB0Z@1386|Bacillus	91061|Bacilli	KL	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
k59_806535_1	159087.Daro_3159	4.8e-27	107.0	COG0144@1|root,COG0144@2|Bacteria,1MV2Q@1224|Proteobacteria,2VI1D@28216|Betaproteobacteria,2KUND@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N
k59_806535_2	159087.Daro_3160	5.93e-78	241.0	COG3087@1|root,COG3087@2|Bacteria,1RCA5@1224|Proteobacteria,2VTK8@28216|Betaproteobacteria,2KWEX@206389|Rhodocyclales	206389|Rhodocyclales	D	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
k59_1048164_1	580332.Slit_2919	1.17e-24	93.6	COG3313@1|root,COG3313@2|Bacteria,1Q968@1224|Proteobacteria,2WCHA@28216|Betaproteobacteria,44W3E@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF1289)	-	-	-	ko:K06938	-	-	-	-	ko00000	-	-	-	DUF1289
k59_1162858_1	387093.SUN_0131	0.0	1472.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,43DMZ@68525|delta/epsilon subdivisions,2YMMS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_1162858_2	1165841.SULAR_10364	5.4e-119	376.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2YMP9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5,RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_696487_1	159087.Daro_1758	5.3e-67	209.0	COG1806@1|root,COG1806@2|Bacteria,1MUHU@1224|Proteobacteria,2VI4R@28216|Betaproteobacteria,2KVFV@206389|Rhodocyclales	206389|Rhodocyclales	F	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation	-	-	2.7.11.33,2.7.4.28	ko:K09773	-	-	-	-	ko00000,ko01000	-	-	-	Kinase-PPPase
k59_329607_1	1537917.JU82_09875	1.21e-78	244.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,42NDT@68525|delta/epsilon subdivisions,2YMIS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
k59_1509312_1	159087.Daro_3838	1.05e-91	275.0	COG0348@1|root,COG0348@2|Bacteria,1MWR5@1224|Proteobacteria,2VJYI@28216|Betaproteobacteria,2KUNK@206389|Rhodocyclales	206389|Rhodocyclales	C	4Fe-4S binding domain	napH	-	-	ko:K02574	-	-	-	-	ko00000	-	-	-	Fer4_5,Fer4_6
k59_1099976_1	944547.ABLL_1134	7.47e-23	95.1	COG0177@1|root,COG0177@2|Bacteria,1RAK3@1224|Proteobacteria,42M4V@68525|delta/epsilon subdivisions,2YNKT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	tigr02757	-	-	-	-	-	-	-	-	-	-	-	-	DUF2400
k59_1099976_2	1249480.B649_07350	1.29e-46	160.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,42M3C@68525|delta/epsilon subdivisions,2YMHJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
k59_1868476_1	945713.IALB_2115	2.11e-115	337.0	COG0207@1|root,COG0207@2|Bacteria	2|Bacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	GO:0000287,GO:0003674,GO:0003824,GO:0004799,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009125,GO:0009129,GO:0009130,GO:0009131,GO:0009157,GO:0009159,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009178,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009314,GO:0009394,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0032259,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042083,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046073,GO:0046078,GO:0046079,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b2827,iAPECO1_1312.APECO1_3678,iBWG_1329.BWG_2562,iE2348C_1286.E2348C_3096,iEC042_1314.EC042_3024,iEC55989_1330.EC55989_3103,iECABU_c1320.ECABU_c31240,iECDH10B_1368.ECDH10B_2997,iECDH1ME8569_1439.ECDH1ME8569_2734,iECED1_1282.ECED1_3283,iECH74115_1262.ECH74115_4093,iECIAI1_1343.ECIAI1_2935,iECIAI39_1322.ECIAI39_3246,iECNA114_1301.ECNA114_2885,iECO103_1326.ECO103_3386,iECO111_1330.ECO111_3555,iECO26_1355.ECO26_3899,iECOK1_1307.ECOK1_3231,iECP_1309.ECP_2840,iECS88_1305.ECS88_3122,iECSE_1348.ECSE_3084,iECSF_1327.ECSF_2642,iECSP_1301.ECSP_3779,iECUMN_1333.ECUMN_3154,iECW_1372.ECW_m3069,iECs_1301.ECs3684,iEKO11_1354.EKO11_0914,iETEC_1333.ETEC_3014,iEcDH1_1363.EcDH1_0864,iEcE24377_1341.EcE24377A_3147,iEcSMS35_1347.EcSMS35_2974,iG2583_1286.G2583_3481,iJO1366.b2827,iJR904.b2827,iLF82_1304.LF82_2267,iNRG857_1313.NRG857_13965,iSSON_1240.SSON_2984,iUMN146_1321.UM146_02290,iUMNK88_1353.UMNK88_3511,iUTI89_1310.UTI89_C3229,iWFL_1372.ECW_m3069,iY75_1357.Y75_RS14705,iYL1228.KPN_03236,iZ_1308.Z4144,ic_1306.c3422	Thymidylat_synt
k59_1331961_1	709032.Sulku_2198	1.91e-51	179.0	COG0715@1|root,COG0834@1|root,COG2199@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42UTN@68525|delta/epsilon subdivisions,2YTHQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EPT	NMT1/THI5 like	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	GGDEF,NMT1,SBP_bac_3
k59_577815_1	748247.AZKH_1536	2.53e-103	303.0	COG5424@1|root,COG5424@2|Bacteria,1MW7G@1224|Proteobacteria,2VI0X@28216|Betaproteobacteria,2KUDW@206389|Rhodocyclales	206389|Rhodocyclales	H	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ	pqqC	-	1.3.3.11	ko:K06137	-	-	-	-	ko00000,ko01000	-	-	-	TENA_THI-4
k59_577815_2	983917.RGE_40520	2.61e-26	104.0	COG1235@1|root,COG1235@2|Bacteria,1MWI5@1224|Proteobacteria,2VJUF@28216|Betaproteobacteria,1KKAC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	May be involved in the transport of PQQ or its precursor to the periplasm	pqqB	-	-	ko:K06136	-	-	-	-	ko00000	-	-	-	Lactamase_B_2
k59_1801841_1	1123325.JHUV01000012_gene1069	3.68e-35	137.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,2G3MB@200783|Aquificae	200783|Aquificae	M	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II	-	-	2.7.7.13,5.4.2.8	ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II
k59_275387_1	545695.TREAZ_1514	9.74e-51	172.0	COG3039@1|root,COG3039@2|Bacteria,2J8QG@203691|Spirochaetes	203691|Spirochaetes	L	hmm pf01609	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
k59_1162913_1	1249480.B649_07935	3.34e-172	497.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2YMXZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	ABC transporter, ATP-binding protein	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
k59_452227_2	709032.Sulku_0821	4.07e-55	177.0	COG0352@1|root,COG0352@2|Bacteria,1NMR6@1224|Proteobacteria,42TSZ@68525|delta/epsilon subdivisions,2YPHK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Thiamine monophosphate synthase	-	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
k59_1216323_2	1165841.SULAR_06608	8.8e-41	142.0	COG2191@1|root,COG2191@2|Bacteria,1RD60@1224|Proteobacteria,42SP8@68525|delta/epsilon subdivisions,2YPEF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Formylmethanofuran dehydrogenase, subunit e	-	-	-	-	-	-	-	-	-	-	-	-	FmdE
k59_1100039_1	572480.Arnit_2297	2.65e-49	165.0	COG2207@1|root,COG3449@1|root,COG2207@2|Bacteria,COG3449@2|Bacteria,1MWTF@1224|Proteobacteria,42PYD@68525|delta/epsilon subdivisions,2YN6I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	PFAM Bacterial transcription activator, effector binding domain	-	-	-	ko:K13652	-	-	-	-	ko00000,ko03000	-	-	-	GyrI-like,HTH_18
k59_1458485_1	748247.AZKH_p0622	3.56e-58	182.0	COG2346@1|root,COG2346@2|Bacteria,1N005@1224|Proteobacteria,2VUPJ@28216|Betaproteobacteria,2KZHR@206389|Rhodocyclales	206389|Rhodocyclales	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
k59_1458485_2	713586.KB900536_gene1967	2.58e-24	99.8	COG1846@1|root,COG1846@2|Bacteria,1MZS9@1224|Proteobacteria,1SBPM@1236|Gammaproteobacteria,1X16P@135613|Chromatiales	135613|Chromatiales	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
k59_329697_1	159087.Daro_0164	5.35e-44	149.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,2VK4I@28216|Betaproteobacteria,2KUFM@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
k59_329697_2	159087.Daro_0163	1.02e-63	214.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2VJ57@28216|Betaproteobacteria,2KUC6@206389|Rhodocyclales	206389|Rhodocyclales	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_162994_1	207559.Dde_0210	5.3e-34	131.0	COG0492@1|root,COG0526@1|root,COG0492@2|Bacteria,COG0526@2|Bacteria,1MV15@1224|Proteobacteria,43BCX@68525|delta/epsilon subdivisions,2X6RV@28221|Deltaproteobacteria,2MH5Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Thioredoxin domain	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Thioredoxin_3
k59_163032_1	387093.SUN_1886	1.75e-118	363.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,42MTZ@68525|delta/epsilon subdivisions,2YMPF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
k59_1458551_1	1435356.Y013_25425	3.67e-08	54.7	COG0745@1|root,COG0745@2|Bacteria,2GJ2N@201174|Actinobacteria,4FUQS@85025|Nocardiaceae	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	kdpE	GO:0008150,GO:0040007	-	ko:K02483,ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_1458551_2	1123261.AXDW01000010_gene451	2.63e-71	232.0	COG1132@1|root,COG1132@2|Bacteria,1MXC2@1224|Proteobacteria,1RZQR@1236|Gammaproteobacteria,1XCEP@135614|Xanthomonadales	135614|Xanthomonadales	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_tran
k59_1577003_2	563040.Saut_0557	4.33e-93	280.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,42MHF@68525|delta/epsilon subdivisions,2YN0G@29547|Epsilonproteobacteria	68525|delta/epsilon subdivisions	C	E1 component alpha subunit	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
k59_1458556_2	1165841.SULAR_09669	7.7e-20	87.8	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,42ME1@68525|delta/epsilon subdivisions,2YMI9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
k59_163066_1	1537917.JU82_08395	2.84e-25	97.4	COG0811@1|root,COG0811@2|Bacteria,1RK2P@1224|Proteobacteria,42TPV@68525|delta/epsilon subdivisions,2YPGE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Biopolymer transporter ExbB	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k59_163066_2	1537917.JU82_08390	7.87e-86	260.0	COG0642@1|root,COG0642@2|Bacteria,1QZ1Z@1224|Proteobacteria,42SN7@68525|delta/epsilon subdivisions,2YPK7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
k59_219809_1	589865.DaAHT2_2434	9.59e-27	114.0	COG2199@1|root,COG2203@1|root,COG2206@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,42QQI@68525|delta/epsilon subdivisions,2X706@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM Metal-dependent phosphohydrolase, HD	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD,dCache_2
k59_1332149_1	550540.Fbal_3608	4.17e-10	61.2	2DNBN@1|root,32WN2@2|Bacteria,1N5BF@1224|Proteobacteria,1S7CH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3313)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3313
k59_1868614_1	1485544.JQKP01000001_gene942	2.81e-79	265.0	COG2132@1|root,COG4733@1|root,COG2132@2|Bacteria,COG4733@2|Bacteria,1R9AF@1224|Proteobacteria,2WF05@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_696718_2	709032.Sulku_1036	8.92e-27	110.0	COG1032@1|root,COG1032@2|Bacteria,1Q5NG@1224|Proteobacteria,42N2D@68525|delta/epsilon subdivisions,2YNAR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4080,Radical_SAM
k59_923792_1	1120998.AUFC01000051_gene568	1.04e-08	53.9	2DQE0@1|root,33689@2|Bacteria,1VH8J@1239|Firmicutes,24WJ6@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1685474_1	580340.Tlie_0664	3.36e-07	48.5	COG1841@1|root,COG1841@2|Bacteria,3TBK5@508458|Synergistetes	508458|Synergistetes	J	Ribosomal protein L30	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
k59_1685474_2	717773.Thicy_0139	3.47e-66	206.0	COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,1RNEV@1236|Gammaproteobacteria,460ID@72273|Thiotrichales	72273|Thiotrichales	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
k59_1685474_3	859657.RPSI07_0495	5.52e-20	83.2	COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,2VSH0@28216|Betaproteobacteria,1K7WM@119060|Burkholderiaceae	28216|Betaproteobacteria	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
k59_1393036_1	159087.Daro_3335	2.55e-102	305.0	COG0182@1|root,COG0182@2|Bacteria,1MUPM@1224|Proteobacteria,2VI2X@28216|Betaproteobacteria,2KVMX@206389|Rhodocyclales	206389|Rhodocyclales	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
k59_1802040_1	1537917.JU82_05115	4.53e-73	233.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,42NBJ@68525|delta/epsilon subdivisions,2YMTY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Mg chelatase-related protein	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
k59_1050260_1	387093.SUN_0591	5.42e-37	135.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,42MHH@68525|delta/epsilon subdivisions,2YMRT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_64173_2	1168067.JAGP01000001_gene1930	7.24e-77	244.0	COG2759@1|root,COG2759@2|Bacteria,1MUR8@1224|Proteobacteria,1RME6@1236|Gammaproteobacteria,46012@72273|Thiotrichales	72273|Thiotrichales	F	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
k59_1533449_1	1249480.B649_03240	7.11e-160	456.0	COG2046@1|root,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,42NAI@68525|delta/epsilon subdivisions,2YME3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	sulfate adenylyltransferase	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
k59_476155_1	1100720.ALKN01000033_gene740	1.42e-65	211.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,2VI9I@28216|Betaproteobacteria,4AB1H@80864|Comamonadaceae	28216|Betaproteobacteria	P	ammonium transporter	-	-	-	ko:K03320,ko:K06580	-	-	-	-	ko00000,ko02000,ko04090	1.A.11,1.A.11.4	-	-	Ammonium_transp
k59_476155_2	1219077.VAZ01S_031_00080	1.35e-26	107.0	COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,1RMNQ@1236|Gammaproteobacteria,1XTY6@135623|Vibrionales	135623|Vibrionales	E	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls	dapE	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009014,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
k59_64174_1	1449065.JMLL01000013_gene2756	5.88e-24	105.0	COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,2TSP0@28211|Alphaproteobacteria,43NZG@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	M	HlyD membrane-fusion protein of T1SS	-	-	-	ko:K02022	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD,HlyD_3
k59_1591235_1	1278309.KB907105_gene1517	1.95e-45	164.0	COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XH59@135619|Oceanospirillales	1236|Gammaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9
k59_593103_1	387093.SUN_1796	1.32e-125	382.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,42MKB@68525|delta/epsilon subdivisions,2YMIZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
k59_1004747_1	709032.Sulku_0725	1.17e-52	176.0	COG3034@1|root,COG3034@2|Bacteria,1N2B6@1224|Proteobacteria,42QS4@68525|delta/epsilon subdivisions,2YNYQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	ErfK YbiS YcfS YnhG family protein	pgp2	-	-	-	-	-	-	-	-	-	-	-	YkuD
k59_1004747_2	1249480.B649_08705	2.31e-09	56.6	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,42MUR@68525|delta/epsilon subdivisions,2YMG3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
k59_1180287_1	637910.ROD_11451	1.72e-13	69.7	COG0583@1|root,COG0583@2|Bacteria,1MU4C@1224|Proteobacteria,1RY6W@1236|Gammaproteobacteria,3WXQI@544|Citrobacter	1236|Gammaproteobacteria	K	LysR substrate binding domain	ttdR	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_1180287_2	1304883.KI912532_gene3108	6.67e-27	108.0	COG2225@1|root,COG2225@2|Bacteria,1MVEV@1224|Proteobacteria,2VJK0@28216|Betaproteobacteria,2KVUU@206389|Rhodocyclales	206389|Rhodocyclales	C	Malate synthase	-	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
k59_1827133_1	159087.Daro_1225	2.32e-105	315.0	2C7MP@1|root,2Z7Q4@2|Bacteria,1NHK1@1224|Proteobacteria,2VPW1@28216|Betaproteobacteria,2KV1A@206389|Rhodocyclales	206389|Rhodocyclales	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_32
k59_123788_2	1249480.B649_08130	3.86e-35	134.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42UBD@68525|delta/epsilon subdivisions,2YRGP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	7TM diverse intracellular signalling	-	-	-	ko:K20971	ko02025,map02025	-	-	-	ko00000,ko00001,ko01001,ko02022	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c
k59_1591282_1	1123517.JOMR01000001_gene1456	1.58e-47	174.0	COG4564@1|root,COG5001@1|root,COG4564@2|Bacteria,COG5001@2|Bacteria,1R4H0@1224|Proteobacteria,1RS9G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,dCache_1
k59_593163_1	1165841.SULAR_05313	1.07e-95	293.0	COG4972@1|root,COG4972@2|Bacteria,1QA6M@1224|Proteobacteria,42NDB@68525|delta/epsilon subdivisions,2YMP2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Pilus assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1062238_1	159087.Daro_1607	6.95e-22	87.0	2E3TT@1|root,32YR7@2|Bacteria,1N9R9@1224|Proteobacteria,2VXTK@28216|Betaproteobacteria,2M02X@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1062238_2	159087.Daro_1608	1.12e-66	219.0	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,2VH50@28216|Betaproteobacteria,2KUWX@206389|Rhodocyclales	206389|Rhodocyclales	I	Poly(R)-hydroxyalkanoic acid synthase, class I	-	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	PhaC_N
k59_1122109_1	1165841.SULAR_03777	2.3e-61	209.0	COG1449@1|root,COG1449@2|Bacteria,1P2YJ@1224|Proteobacteria,42N8E@68525|delta/epsilon subdivisions,2YNF0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
k59_945940_1	436717.AOLE_14915	4.58e-27	111.0	COG4733@1|root,COG4733@2|Bacteria,1QVD7@1224|Proteobacteria,1SI9S@1236|Gammaproteobacteria,3NMSC@468|Moraxellaceae	1236|Gammaproteobacteria	S	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage-tail_3,fn3
k59_1708437_1	1537917.JU82_08205	6.22e-67	221.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,42N1K@68525|delta/epsilon subdivisions,2YMYX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1g,tRNA_bind
k59_1708437_2	1537917.JU82_08200	6.51e-112	329.0	COG0770@1|root,COG0770@2|Bacteria,1Q5GZ@1224|Proteobacteria,42RQ8@68525|delta/epsilon subdivisions,2YP4M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity	-	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	-
k59_1004832_1	1165841.SULAR_09769	1.31e-143	409.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,42N84@68525|delta/epsilon subdivisions,2YM7V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0510	DapB_C,DapB_N
k59_1004832_2	387093.SUN_0234	2.8e-47	160.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,42MHR@68525|delta/epsilon subdivisions,2YN1K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_181252_2	159087.Daro_1608	3.31e-117	352.0	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,2VH50@28216|Betaproteobacteria,2KUWX@206389|Rhodocyclales	206389|Rhodocyclales	I	Poly(R)-hydroxyalkanoic acid synthase, class I	-	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	PhaC_N
k59_357858_1	153948.NAL212_1671	8.06e-64	214.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VI5B@28216|Betaproteobacteria,372QZ@32003|Nitrosomonadales	28216|Betaproteobacteria	NT	Histidine kinase	cheA	GO:0003674,GO:0005488,GO:0005515,GO:0019904	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,CheY-binding,H-kinase_dim,HATPase_c,Hpt
k59_123850_2	1165841.SULAR_00300	1.4e-25	102.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,42PKA@68525|delta/epsilon subdivisions,2YP35@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the protein N5-glutamine methyltransferase family	hemK	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
k59_828527_1	1249627.D779_0071	1.18e-84	263.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,1RP7U@1236|Gammaproteobacteria,1WX4J@135613|Chromatiales	135613|Chromatiales	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
k59_1240060_1	1165841.SULAR_06448	4.37e-112	344.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2YMI5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	cation transport ATPase	ccoI	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
k59_240848_1	1537917.JU82_07415	8.98e-46	155.0	COG0451@1|root,COG0451@2|Bacteria,1MVE4@1224|Proteobacteria,42MC1@68525|delta/epsilon subdivisions,2YMD0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	ADP-L-glycero-D-manno-heptose-6-epimerase	waaD	-	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase
k59_240848_2	709032.Sulku_2145	4.02e-32	113.0	COG2863@1|root,COG2863@2|Bacteria,1PDTH@1224|Proteobacteria,42W2E@68525|delta/epsilon subdivisions,2YQDN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome c553	cccA	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,Cytochrome_CBB3
k59_1062285_1	397945.Aave_3829	1.77e-112	339.0	COG2223@1|root,COG2223@2|Bacteria,1MWC7@1224|Proteobacteria,2WHGT@28216|Betaproteobacteria,4AD5I@80864|Comamonadaceae	28216|Betaproteobacteria	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_1827232_1	1537917.JU82_02305	5.28e-35	134.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,42MMR@68525|delta/epsilon subdivisions,2YMF0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	GM	Polysaccharide biosynthesis protein	pglF	-	4.2.1.135	ko:K15912	ko00520,map00520	-	-	-	ko00000,ko00001,ko01000	-	-	-	Polysacc_synt_2
k59_1827232_2	362418.IW19_06570	3.57e-10	62.4	COG0399@1|root,COG0399@2|Bacteria,4NFAI@976|Bacteroidetes,1HX99@117743|Flavobacteriia,2NTTM@237|Flavobacterium	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	pglE	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
k59_653245_1	709032.Sulku_1510	2.12e-26	106.0	COG0535@1|root,COG1433@1|root,COG0535@2|Bacteria,COG1433@2|Bacteria,1MWDC@1224|Proteobacteria,42MHB@68525|delta/epsilon subdivisions,2YNUZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Nitrogenase cofactor biosynthesis protein NifB	-	-	-	ko:K02585	-	-	-	-	ko00000	-	-	-	Nitro_FeMo-Co,Radical_SAM
k59_243040_1	1123326.JFBL01000002_gene1587	1.08e-106	332.0	COG3437@1|root,COG4564@1|root,COG3437@2|Bacteria,COG4564@2|Bacteria,1QUN9@1224|Proteobacteria,42PB6@68525|delta/epsilon subdivisions,2YTKF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,PAS_9,Response_reg
k59_243040_2	1122165.AUHS01000005_gene1708	4.98e-32	123.0	COG2199@1|root,COG3706@2|Bacteria,1MXAW@1224|Proteobacteria,1RZ41@1236|Gammaproteobacteria,1JD3Q@118969|Legionellales	1236|Gammaproteobacteria	FT	diguanylate cyclase	-	-	2.7.7.65	ko:K13590	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000	-	-	-	GAF,GGDEF,PAS_4,Reg_prop,Y_Y_Y
k59_1535943_1	159087.Daro_3715	1.33e-78	250.0	COG1231@1|root,COG1231@2|Bacteria,1QWEG@1224|Proteobacteria,2WGZI@28216|Betaproteobacteria,2KU7M@206389|Rhodocyclales	206389|Rhodocyclales	E	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8
k59_1710670_2	709032.Sulku_2261	8.44e-143	413.0	COG0845@1|root,COG0845@2|Bacteria,1QMYR@1224|Proteobacteria,42WWX@68525|delta/epsilon subdivisions,2YR01@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	RND family efflux transporter, MFP subunit	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
k59_9663_1	1454004.AW11_02048	1.19e-36	138.0	COG2959@1|root,COG2959@2|Bacteria,1MY3A@1224|Proteobacteria,2VMG1@28216|Betaproteobacteria	28216|Betaproteobacteria	H	enzyme of heme biosynthesis	hemX	-	2.1.1.107,4.2.1.75	ko:K02496,ko:K13543	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,HemX
k59_9663_2	305700.B447_21282	1.84e-09	58.5	COG3071@1|root,COG3071@2|Bacteria,1MU7A@1224|Proteobacteria,2VK6P@28216|Betaproteobacteria,2KVAI@206389|Rhodocyclales	206389|Rhodocyclales	H	enzyme of heme biosynthesis	hemY	-	-	ko:K02498	-	-	-	-	ko00000	-	-	-	HemY_N
k59_1007438_2	159087.Daro_4169	4.47e-40	133.0	COG0236@1|root,COG0236@2|Bacteria,1NFPT@1224|Proteobacteria,2VX2W@28216|Betaproteobacteria,2KXAB@206389|Rhodocyclales	206389|Rhodocyclales	IQ	Phosphopantetheine attachment site	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
k59_830902_1	1112209.AHVZ01000037_gene2791	1.09e-63	218.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,1RMMQ@1236|Gammaproteobacteria,3NJA4@468|Moraxellaceae	1236|Gammaproteobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
k59_243054_1	1249480.B649_06075	1.34e-15	74.3	COG1999@1|root,COG1999@2|Bacteria,1Q4TG@1224|Proteobacteria,42ZV5@68525|delta/epsilon subdivisions,2YRVW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
k59_243054_2	387093.SUN_0581	1.92e-69	214.0	COG1014@1|root,COG1014@2|Bacteria,1R8XG@1224|Proteobacteria,42NPD@68525|delta/epsilon subdivisions,2YMM0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	oxidoreductase	oorC	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
k59_1357923_1	1537917.JU82_06405	4.54e-151	444.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,42NN7@68525|delta/epsilon subdivisions,2YMKH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
k59_1593490_1	709032.Sulku_0939	7.2e-125	375.0	COG1315@1|root,COG1315@2|Bacteria,1R5P6@1224|Proteobacteria,42MAS@68525|delta/epsilon subdivisions,2YM7Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Flagellar Assembly Protein A	-	-	-	-	-	-	-	-	-	-	-	-	FapA
k59_1829674_1	118163.Ple7327_0788	1.76e-48	177.0	COG1716@1|root,COG2202@1|root,COG2203@1|root,COG5001@1|root,COG1716@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,3VII1@52604|Pleurocapsales	1117|Cyanobacteria	T	Diguanylate cyclase (GGDEF)	-	-	-	-	-	-	-	-	-	-	-	-	EAL,FHA,GAF,GGDEF,PAS,PAS_9
k59_1064842_1	90814.KL370891_gene846	1.33e-60	201.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1SYRX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Protoglobin
k59_888983_1	944546.ABED_1902	4.6e-47	155.0	2DWBF@1|root,33ZFM@2|Bacteria,1NY3M@1224|Proteobacteria,42TCY@68525|delta/epsilon subdivisions,2YPPU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1593498_1	580332.Slit_1054	2.92e-95	300.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VKYE@28216|Betaproteobacteria,44W7M@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_1124743_1	1249480.B649_11740	1.61e-70	238.0	COG3164@1|root,COG3164@2|Bacteria,1QUYX@1224|Proteobacteria,43CES@68525|delta/epsilon subdivisions,2YTC9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
k59_1417860_1	709032.Sulku_1586	2.06e-84	256.0	COG2227@1|root,COG2227@2|Bacteria,1NN3B@1224|Proteobacteria,43C3V@68525|delta/epsilon subdivisions,2YTAM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs	cmoB	-	-	ko:K15257	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_9
k59_1535990_1	1123514.KB905899_gene1224	6.83e-21	100.0	COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,1RQR7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	protein conserved in bacteria	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
k59_66127_1	709032.Sulku_2228	1.02e-40	148.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,42M70@68525|delta/epsilon subdivisions,2YMJM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_538474_1	598659.NAMH_0290	7.8e-61	197.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,42MNA@68525|delta/epsilon subdivisions,2YMK1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	OU	signal peptide peptidase SppA, 36K type	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
k59_830955_1	666681.M301_2552	3.31e-34	126.0	COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,2VJN7@28216|Betaproteobacteria,2KKW6@206350|Nitrosomonadales	206350|Nitrosomonadales	T	PFAM ATP-binding region ATPase domain protein	-	-	2.7.13.3	ko:K07708	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4
k59_830955_2	1502770.JQMG01000001_gene595	4.99e-125	367.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,2KM9J@206350|Nitrosomonadales	206350|Nitrosomonadales	T	TIGRFAM nitrogen regulation protein NR(I)	-	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_1182546_1	1565314.OA34_03405	1.81e-36	141.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2YN7R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Cache_2	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,dCache_2,sCache_2
k59_1242794_1	1123517.JOMR01000001_gene866	9.26e-101	296.0	COG0717@1|root,COG0717@2|Bacteria,1MV2J@1224|Proteobacteria,1RMCD@1236|Gammaproteobacteria,460AM@72273|Thiotrichales	72273|Thiotrichales	F	Belongs to the dCTP deaminase family	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	Intein_splicing,dUTPase
k59_1242794_2	1220582.RRU01S_25_01310	8.15e-12	65.1	COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,2TRY6@28211|Alphaproteobacteria,4B8H9@82115|Rhizobiaceae	28211|Alphaproteobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	GO:0003674,GO:0003824,GO:0004644,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N,YjbR
k59_243120_1	709032.Sulku_2474	1.12e-52	177.0	29Y2F@1|root,30JVD@2|Bacteria,1RAWX@1224|Proteobacteria,4300B@68525|delta/epsilon subdivisions,2YRWY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_300686_1	96561.Dole_1179	6.98e-32	120.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,42PSG@68525|delta/epsilon subdivisions,2WKYN@28221|Deltaproteobacteria,2MJ9P@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	yggS	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
k59_770495_1	1537917.JU82_10775	1.48e-13	71.2	COG0745@1|root,COG0745@2|Bacteria,1QXJT@1224|Proteobacteria,42V47@68525|delta/epsilon subdivisions,2YQ8S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	RESPONSE REGULATOR receiver	-	-	-	ko:K07288	-	-	-	-	ko00000	-	-	-	-
k59_770495_3	1537917.JU82_10785	1.61e-34	119.0	COG1826@1|root,COG1826@2|Bacteria,1NGDP@1224|Proteobacteria,42VNG@68525|delta/epsilon subdivisions,2YQ9F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
k59_1007533_2	1249480.B649_01475	7.31e-49	167.0	COG1883@1|root,COG1883@2|Bacteria,1MV0G@1224|Proteobacteria,42MH1@68525|delta/epsilon subdivisions,2YNK3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1883 Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit	-	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
k59_419154_2	1537917.JU82_09165	5.64e-206	575.0	COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,42MAU@68525|delta/epsilon subdivisions,2YMBU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgI	-	-	ko:K02394	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgI
k59_419154_3	1537917.JU82_09170	2.81e-77	234.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,42U1F@68525|delta/epsilon subdivisions,2YP4X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	methyltransferase	rsmD	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth95
k59_1652233_1	159087.Daro_1624	2.3e-106	322.0	COG0598@1|root,COG0598@2|Bacteria,1R7FC@1224|Proteobacteria,2VKBA@28216|Betaproteobacteria,2KUWR@206389|Rhodocyclales	206389|Rhodocyclales	P	Magnesium transport protein CorA	-	-	-	-	-	-	-	-	-	-	-	-	CorA
k59_300715_1	626418.bglu_1g26950	1.47e-48	159.0	COG3794@1|root,COG3794@2|Bacteria,1RH5A@1224|Proteobacteria,2VSEN@28216|Betaproteobacteria,1K851@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Domain of unknown function (DUF4399)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4399
k59_1358012_1	159087.Daro_2387	1.16e-93	283.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2VH4Z@28216|Betaproteobacteria,2KV70@206389|Rhodocyclales	206389|Rhodocyclales	E	Aminotransferase	-	-	2.6.1.2,2.6.1.66	ko:K14260	ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230	-	R00258,R01215	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_9759_2	367737.Abu_0564	2.83e-28	112.0	COG0475@1|root,COG0475@2|Bacteria,1N2RV@1224|Proteobacteria,43B2N@68525|delta/epsilon subdivisions,2YT5E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
k59_300716_1	159087.Daro_3649	2.75e-60	192.0	COG0664@1|root,COG0664@2|Bacteria,1R6BV@1224|Proteobacteria,2VN3A@28216|Betaproteobacteria,2KVAG@206389|Rhodocyclales	206389|Rhodocyclales	K	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	nnr	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
k59_1124846_1	1123514.KB905903_gene373	7.69e-92	286.0	COG1760@1|root,COG1760@2|Bacteria,1MUZN@1224|Proteobacteria,1RMJZ@1236|Gammaproteobacteria,460AX@72273|Thiotrichales	72273|Thiotrichales	E	Serine dehydratase beta chain	-	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha,SDH_beta
k59_1124846_2	545264.KB898754_gene1815	2.69e-18	84.3	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1WWSC@135613|Chromatiales	135613|Chromatiales	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_655800_1	1249480.B649_09845	1.83e-87	268.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2YNF8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	flgR	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_479041_2	1249480.B649_00380	5.92e-45	147.0	2BRG4@1|root,32MA7@2|Bacteria,1Q36H@1224|Proteobacteria,42WUT@68525|delta/epsilon subdivisions,2YQQJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_479041_3	1249480.B649_00375	2.72e-20	86.3	2A50M@1|root,30TNT@2|Bacteria,1PDM4@1224|Proteobacteria,42QJ6@68525|delta/epsilon subdivisions,2YPYD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	AMIN domain	-	-	-	-	-	-	-	-	-	-	-	-	AMIN
k59_243193_1	1249480.B649_02565	2.42e-102	308.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,42M14@68525|delta/epsilon subdivisions,2YMWB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Biotin carboxylase	pycA	-	6.3.4.14,6.4.1.1,6.4.1.2	ko:K01959,ko:K01961	ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko01230,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212,map01230	M00082,M00173,M00376,M00620	R00344,R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
k59_479047_2	1537917.JU82_09295	1.8e-11	61.6	COG0352@1|root,COG0352@2|Bacteria,1Q57E@1224|Proteobacteria,42T8S@68525|delta/epsilon subdivisions,2YPQM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Thiamine monophosphate synthase	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
k59_595778_2	1172190.M947_03965	3.45e-28	110.0	COG0045@1|root,COG0045@2|Bacteria,1PYM0@1224|Proteobacteria,42YXJ@68525|delta/epsilon subdivisions,2YR3Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	ATP citrate lyase citrate-binding	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_2,Citrate_bind
k59_479053_1	596151.DesfrDRAFT_0929	3.28e-13	73.9	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,42PWE@68525|delta/epsilon subdivisions,2X5DI@28221|Deltaproteobacteria,2MGPW@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
k59_1299526_1	1249480.B649_00260	1.08e-46	169.0	COG3144@1|root,COG3144@2|Bacteria,1PBUJ@1224|Proteobacteria,42VQM@68525|delta/epsilon subdivisions,2YQGT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Flagellar hook-length control protein FliK	-	-	-	-	-	-	-	-	-	-	-	-	Flg_hook
k59_1316084_1	159087.Daro_0267	3.97e-77	256.0	COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2VJGC@28216|Betaproteobacteria,2KUJ8@206389|Rhodocyclales	206389|Rhodocyclales	C	COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits	-	-	1.2.7.8	ko:K04090	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR,TPP_enzyme_C
k59_908134_1	511145.b2329	7.5e-43	149.0	COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,1RMQS@1236|Gammaproteobacteria,3XNA3@561|Escherichia	1236|Gammaproteobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	iE2348C_1286.E2348C_2469,iEC55989_1330.EC55989_2573,iECO103_1326.ECO103_2794,iECO111_1330.ECO111_3077,iECO26_1355.ECO26_3317,iECSE_1348.ECSE_2638,iECW_1372.ECW_m2518,iEKO11_1354.EKO11_1436,iSSON_1240.SSON_2387,iUMNK88_1353.UMNK88_2882,iWFL_1372.ECW_m2518	Chorismate_synt
k59_908134_2	314278.NB231_00910	5.77e-14	73.2	COG0477@1|root,COG2814@2|Bacteria,1MVZI@1224|Proteobacteria,1RPBT@1236|Gammaproteobacteria,1WWHF@135613|Chromatiales	135613|Chromatiales	EGP	Major facilitator superfamily	-	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1_like
k59_1378254_1	1537917.JU82_05800	1.35e-91	286.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,42NAX@68525|delta/epsilon subdivisions,2YN4X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
k59_1853819_1	1537917.JU82_00545	3.31e-216	600.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,42NA3@68525|delta/epsilon subdivisions,2YMD9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k59_563220_1	1249480.B649_04855	4.58e-86	264.0	COG1306@1|root,COG1306@2|Bacteria,1MWBY@1224|Proteobacteria,42NSR@68525|delta/epsilon subdivisions,2YP0V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Putative glycosyl hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4015
k59_1671860_1	1537917.JU82_09115	1.37e-97	289.0	COG1792@1|root,COG1792@2|Bacteria,1QB26@1224|Proteobacteria,42MF4@68525|delta/epsilon subdivisions,2YNT9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Rod shape-determining protein MreC	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
k59_1034181_1	159087.Daro_3044	2.2e-88	260.0	COG1047@1|root,COG1047@2|Bacteria,1RHD1@1224|Proteobacteria,2VRJ4@28216|Betaproteobacteria,2KX0N@206389|Rhodocyclales	206389|Rhodocyclales	O	Peptidyl-prolyl cis-trans	fkpB	-	5.2.1.8	ko:K03774	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
k59_1034181_2	381666.H16_A3047	1.22e-05	46.2	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,2VSEP@28216|Betaproteobacteria,1K1IQ@119060|Burkholderiaceae	28216|Betaproteobacteria	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
k59_680080_1	929558.SMGD1_2812	2.67e-46	164.0	COG1807@1|root,COG1807@2|Bacteria,1P6JE@1224|Proteobacteria,42Z03@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
k59_1788513_1	316274.Haur_1307	6.03e-50	170.0	COG2003@1|root,COG2003@2|Bacteria,2G6BK@200795|Chloroflexi,375AQ@32061|Chloroflexia	32061|Chloroflexia	L	PFAM DNA repair protein RadC	-	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
k59_204644_1	1121035.AUCH01000013_gene3170	5.15e-42	147.0	COG1639@1|root,COG1639@2|Bacteria,1N7EN@1224|Proteobacteria,2VH2Y@28216|Betaproteobacteria,2KW33@206389|Rhodocyclales	206389|Rhodocyclales	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_1086020_1	709032.Sulku_2026	2.86e-56	196.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,42KZI@68525|delta/epsilon subdivisions,2YR60@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Domain of unknown function (DUF3458_C) ARM repeats	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,Peptidase_M1
k59_148529_2	709032.Sulku_1667	3.15e-38	138.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42NFY@68525|delta/epsilon subdivisions,2YRBR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS,PAS_3
k59_438387_1	1249480.B649_05590	1.79e-180	509.0	COG2171@1|root,COG2171@2|Bacteria,1MYKK@1224|Proteobacteria,42MHI@68525|delta/epsilon subdivisions,2YMU8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep_2,THDPS_M,THDPS_N
k59_792830_1	709032.Sulku_1179	8.27e-31	114.0	COG3134@1|root,COG3134@2|Bacteria,1PRQN@1224|Proteobacteria,42TTY@68525|delta/epsilon subdivisions,2YPV8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	17 kDa surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Rick_17kDa_Anti
k59_1674852_1	395494.Galf_1644	2.13e-83	272.0	COG1882@1|root,COG1882@2|Bacteria,1MWBF@1224|Proteobacteria	1224|Proteobacteria	C	Formate acetyltransferase	-	-	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
k59_1271240_1	1286093.C266_13444	1.57e-90	271.0	COG1994@1|root,COG1994@2|Bacteria,1PM1Q@1224|Proteobacteria,2VM3E@28216|Betaproteobacteria,1K6NE@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1791550_1	159087.Daro_1420	1.13e-61	190.0	COG2703@1|root,COG2703@2|Bacteria,1MZJ3@1224|Proteobacteria,2VVGT@28216|Betaproteobacteria,2KZ1F@206389|Rhodocyclales	206389|Rhodocyclales	P	PFAM Hemerythrin HHE cation binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1791550_2	62928.azo1131	1.69e-17	80.1	297UU@1|root,2ZV1D@2|Bacteria,1MXFE@1224|Proteobacteria,2VIEE@28216|Betaproteobacteria,2KWQQ@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_265628_1	1249480.B649_09235	4.22e-35	126.0	COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,42SQE@68525|delta/epsilon subdivisions,2YPHI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	GO:0003674,GO:0003824,GO:0004141,GO:0016874,GO:0016879,GO:0016882	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
k59_265628_2	1537917.JU82_06915	8.77e-145	412.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,42NMR@68525|delta/epsilon subdivisions,2YN8M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k59_1089358_1	159087.Daro_4120	2.39e-14	69.3	COG0537@1|root,COG0537@2|Bacteria,1MZVD@1224|Proteobacteria,2VU7S@28216|Betaproteobacteria,2KWXK@206389|Rhodocyclales	206389|Rhodocyclales	FG	Histidine triad (HIT)	-	-	-	-	-	-	-	-	-	-	-	-	HIT
k59_1089358_2	159087.Daro_4119	4.81e-174	499.0	2A8Z1@1|root,30Y2U@2|Bacteria,1PJYG@1224|Proteobacteria,2VJ83@28216|Betaproteobacteria,2KVGT@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_504963_1	1537917.JU82_00195	5.67e-116	357.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2YNQA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
k59_504963_2	1537917.JU82_00200	1.85e-38	130.0	2AK43@1|root,31ATX@2|Bacteria,1Q64B@1224|Proteobacteria,432D7@68525|delta/epsilon subdivisions,2YSJA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_504963_3	709032.Sulku_1956	1.77e-73	239.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42N03@68525|delta/epsilon subdivisions,2YNMG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	PFAM Methyl-accepting chemotaxis protein (MCP) signaling domain	-	-	-	ko:K03406,ko:K05875	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,MCPsignal
k59_1318952_1	159087.Daro_4201	3.85e-113	342.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,2VHIA@28216|Betaproteobacteria,2KUBX@206389|Rhodocyclales	206389|Rhodocyclales	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
k59_1151646_1	749222.Nitsa_0708	8.86e-27	110.0	COG0490@1|root,COG1226@1|root,COG0490@2|Bacteria,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,42MW6@68525|delta/epsilon subdivisions,2YNJR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	potassium channel protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans,Ion_trans_2,TrkA_C,TrkA_N
k59_1151646_2	1165841.SULAR_04873	2.73e-193	547.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,42M31@68525|delta/epsilon subdivisions,2YMGC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
k59_1674881_1	1537917.JU82_08405	4.35e-87	262.0	COG3751@1|root,COG3751@2|Bacteria,1Q4MK@1224|Proteobacteria,42ZFP@68525|delta/epsilon subdivisions,2YRNS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Prolyl 4-hydroxylase alpha subunit homologues.	-	-	-	ko:K07394	-	-	-	-	ko00000	-	-	-	2OG-FeII_Oxy_3
k59_796588_1	1236541.BALL01000002_gene383	1.59e-46	163.0	28M05@1|root,2ZAF9@2|Bacteria,1MY5U@1224|Proteobacteria,1RRFF@1236|Gammaproteobacteria,2QAXX@267890|Shewanellaceae	1236|Gammaproteobacteria	S	General glycosylation pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_796588_2	981327.F925_01148	8.44e-26	104.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,1RMAY@1236|Gammaproteobacteria,3NJAC@468|Moraxellaceae	1236|Gammaproteobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	iB21_1397.B21_00243,iECBD_1354.ECBD_3376,iECB_1328.ECB_00240,iECD_1391.ECD_00240,iYL1228.KPN_00280	Aldedh
k59_441375_1	1537917.JU82_01190	2.55e-100	297.0	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,42NZY@68525|delta/epsilon subdivisions,2YMSS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	-	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
k59_796603_1	159087.Daro_0847	2.96e-101	303.0	COG3317@1|root,COG3317@2|Bacteria,1N670@1224|Proteobacteria,2VHS5@28216|Betaproteobacteria,2KUM7@206389|Rhodocyclales	206389|Rhodocyclales	M	(Lipo)protein	nlpB	-	-	ko:K07287	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	Lipoprotein_18
k59_974572_1	317025.Tcr_0750	1.35e-42	160.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,4608D@72273|Thiotrichales	72273|Thiotrichales	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k59_1271328_1	1537917.JU82_00515	3.98e-96	282.0	COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,42RHA@68525|delta/epsilon subdivisions,2YNX4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
k59_1791611_1	1165841.SULAR_06638	2.6e-107	315.0	COG0681@1|root,COG0681@2|Bacteria,1QENE@1224|Proteobacteria,42ZRJ@68525|delta/epsilon subdivisions,2YRPB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Peptidase S24-like	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
k59_1733473_1	1249480.B649_08730	1.88e-55	178.0	2BSDA@1|root,32MF9@2|Bacteria,1Q395@1224|Proteobacteria,42WZ0@68525|delta/epsilon subdivisions,2YQT3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1733473_2	1249480.B649_08735	1.03e-46	163.0	COG1450@1|root,COG1450@2|Bacteria,1MVNC@1224|Proteobacteria,43BJ2@68525|delta/epsilon subdivisions,2YN49@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Type II and III secretion system protein	ctsD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	STN,Secretin,Secretin_N_2
k59_208149_1	159087.Daro_0325	4.05e-71	221.0	COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,2VHQN@28216|Betaproteobacteria,2KVIT@206389|Rhodocyclales	206389|Rhodocyclales	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
k59_208149_2	159087.Daro_0326	2.53e-26	99.4	COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,2VQ0A@28216|Betaproteobacteria,2KW4S@206389|Rhodocyclales	206389|Rhodocyclales	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
k59_28172_1	1268239.PALB_25050	4.11e-27	111.0	COG1575@1|root,COG1575@2|Bacteria,1QGM9@1224|Proteobacteria,1TE24@1236|Gammaproteobacteria,2Q2FK@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	H	UbiA prenyltransferase family	-	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
k59_1564358_1	666681.M301_1350	3.91e-113	329.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,2VHCT@28216|Betaproteobacteria,2KKZF@206350|Nitrosomonadales	206350|Nitrosomonadales	L	TIGRFAM hydrolase, TatD family	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
k59_911268_1	1249480.B649_03205	7.4e-28	116.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42S84@68525|delta/epsilon subdivisions,2YPD4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_8,dCache_3
k59_1204825_2	944560.HMPREF9058_2084	1.05e-25	106.0	COG0745@1|root,COG0745@2|Bacteria,2GMG9@201174|Actinobacteria,4D469@85005|Actinomycetales	201174|Actinobacteria	KT	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_974624_1	159087.Daro_1738	1.74e-126	363.0	COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,2VJQQ@28216|Betaproteobacteria,2KV4J@206389|Rhodocyclales	206389|Rhodocyclales	F	Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage	-	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
k59_1319054_1	522306.CAP2UW1_0965	1.82e-42	154.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,2VH19@28216|Betaproteobacteria,1KPPK@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
k59_28186_1	1121035.AUCH01000003_gene1150	2.68e-37	126.0	COG1826@1|root,COG1826@2|Bacteria,1N6S4@1224|Proteobacteria,2VVT6@28216|Betaproteobacteria,2KX8N@206389|Rhodocyclales	206389|Rhodocyclales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
k59_28186_2	159087.Daro_3376	2.38e-34	119.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,2VSMS@28216|Betaproteobacteria,2KWJU@206389|Rhodocyclales	206389|Rhodocyclales	FG	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
k59_1674973_1	1165841.SULAR_09324	4.7e-95	290.0	2C3QV@1|root,2Z7YP@2|Bacteria,1MXAM@1224|Proteobacteria,42QBG@68525|delta/epsilon subdivisions,2YNTS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
k59_319031_1	1537917.JU82_06415	1.37e-85	257.0	COG2860@1|root,COG2860@2|Bacteria,1RHQN@1224|Proteobacteria,42R47@68525|delta/epsilon subdivisions,2YP8Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	UPF0126
k59_28195_1	159087.Daro_3637	1.61e-141	409.0	COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,2VJF4@28216|Betaproteobacteria,2KV1C@206389|Rhodocyclales	206389|Rhodocyclales	H	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site	rbcL	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
k59_28200_2	1537917.JU82_03795	3.94e-53	186.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2YMJS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,NIT,Response_reg
k59_1564409_1	1165841.SULAR_02033	1.24e-55	187.0	2A54K@1|root,30TT8@2|Bacteria,1Q98H@1224|Proteobacteria,4348V@68525|delta/epsilon subdivisions,2YRCN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_152464_1	749222.Nitsa_1229	2.85e-35	120.0	2EA3G@1|root,333F6@2|Bacteria,1NBRP@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4177)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4177
k59_85870_1	416269.APL_0148	2.52e-132	396.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,1RMPV@1236|Gammaproteobacteria,1Y7PP@135625|Pasteurellales	135625|Pasteurellales	F	Ribonucleotide reductase, alpha subunit	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC
k59_85870_2	979533.F1D0U3_9CAUD	1.07e-12	65.5	4QAM4@10239|Viruses,4QWEA@35237|dsDNA viruses  no RNA stage,4QPGM@28883|Caudovirales,4QNJD@10744|Podoviridae	10744|Podoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_85870_3	1121439.dsat_1925	2.29e-29	110.0	2EPDH@1|root,33H03@2|Bacteria,1NKYC@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1038834_1	84531.JMTZ01000002_gene774	1.66e-86	271.0	COG1018@1|root,COG3576@1|root,COG1018@2|Bacteria,COG3576@2|Bacteria,1MU6E@1224|Proteobacteria,1RNA4@1236|Gammaproteobacteria,1X5Y3@135614|Xanthomonadales	135614|Xanthomonadales	C	2Fe-2S iron-sulfur cluster binding domain	pobB	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,FA_desaturase,Fer2,NAD_binding_1
k59_1038834_2	1122599.AUGR01000002_gene3632	6.7e-24	94.7	COG2128@1|root,COG2128@2|Bacteria,1PHJA@1224|Proteobacteria,1SWYB@1236|Gammaproteobacteria,1XQ9B@135619|Oceanospirillales	135619|Oceanospirillales	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
k59_1038842_1	1537917.JU82_06155	4.05e-141	408.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2YMN1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DEAD box helicase family	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k59_684328_1	1449080.JQMV01000003_gene535	8.34e-06	50.4	COG2050@1|root,COG2050@2|Bacteria,1WK1X@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
k59_1675035_1	604331.AUHY01000013_gene2603	2.12e-35	132.0	COG0579@1|root,COG0579@2|Bacteria,1WMNW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	FAD dependent oxidoreductase	-	-	-	ko:K15736	-	-	-	-	ko00000,ko01000	-	-	-	DAO
k59_1733574_2	1249480.B649_06940	2.01e-64	206.0	COG0667@1|root,COG0667@2|Bacteria,1RK6Z@1224|Proteobacteria,42QDH@68525|delta/epsilon subdivisions,2YNCD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_1675044_1	709032.Sulku_1990	1.77e-124	363.0	COG0642@1|root,COG0642@2|Bacteria,1QUJK@1224|Proteobacteria,42PPA@68525|delta/epsilon subdivisions,2YMW6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
k59_1271478_1	709032.Sulku_0835	4.59e-94	299.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2YNQF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0474 Cation transport ATPase	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3,Na_H_Exchanger
k59_1204934_2	1249480.B649_01545	5.6e-28	107.0	COG0847@1|root,COG0847@2|Bacteria,1PDD1@1224|Proteobacteria,42MUX@68525|delta/epsilon subdivisions,2YNB6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG0847 DNA polymerase III epsilon subunit and related 3'-5'	-	-	2.7.7.7	ko:K02342,ko:K10857	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_796811_1	1537917.JU82_00775	2.4e-88	264.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,42N5B@68525|delta/epsilon subdivisions,2YMWV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
k59_796811_2	1537917.JU82_00780	7.95e-53	168.0	COG2198@1|root,COG2198@2|Bacteria,1Q0HI@1224|Proteobacteria,42S4B@68525|delta/epsilon subdivisions,2YP8X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	Hpt
k59_1858035_1	709032.Sulku_1906	4.97e-84	267.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42SS2@68525|delta/epsilon subdivisions,2YRAM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	CZB,MCPsignal
k59_1733599_1	709032.Sulku_0943	2.75e-151	437.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,42MXF@68525|delta/epsilon subdivisions,2YMJ8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Mur ligase middle domain	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
k59_1733604_1	1502770.JQMG01000001_gene784	3.62e-63	205.0	COG2821@1|root,COG2821@2|Bacteria,1MXD4@1224|Proteobacteria,2VHBF@28216|Betaproteobacteria,2KM9X@206350|Nitrosomonadales	206350|Nitrosomonadales	M	MltA specific insert domain	-	-	-	ko:K08304	-	-	-	-	ko00000,ko01000,ko01011	-	GH102	-	3D,MltA
k59_1733604_2	1049564.TevJSym_cl00010	2.25e-34	129.0	COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,1RNDE@1236|Gammaproteobacteria,1J5GM@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1,Thioredoxin_4
k59_1319167_1	269796.Rru_A0243	4.34e-49	172.0	COG0144@1|root,COG0144@2|Bacteria,1MV2Q@1224|Proteobacteria,2TS6U@28211|Alphaproteobacteria,2JQD2@204441|Rhodospirillales	204441|Rhodospirillales	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N
k59_1675073_1	1249480.B649_01475	1.49e-104	316.0	COG1883@1|root,COG1883@2|Bacteria,1MV0G@1224|Proteobacteria,42MH1@68525|delta/epsilon subdivisions,2YNK3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1883 Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit	-	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
k59_1675073_2	1249480.B649_01470	5.8e-26	98.2	COG3630@1|root,COG3630@2|Bacteria	2|Bacteria	C	sodium ion export across plasma membrane	oadG	GO:0003674,GO:0003824,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008948,GO:0015672,GO:0016829,GO:0016830,GO:0016831,GO:0030001,GO:0051179,GO:0051234	4.1.1.3	ko:K01573	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_gamma
k59_1089621_1	159087.Daro_0213	1.17e-18	80.9	COG3168@1|root,COG3168@2|Bacteria,1RI6V@1224|Proteobacteria,2VSVR@28216|Betaproteobacteria,2KWK4@206389|Rhodocyclales	206389|Rhodocyclales	NU	pilus assembly protein PilP	pilP	-	-	ko:K02665	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilP
k59_1089621_2	159087.Daro_0212	5.73e-83	250.0	COG3167@1|root,COG3167@2|Bacteria,1RBGW@1224|Proteobacteria,2VH68@28216|Betaproteobacteria,2KW2A@206389|Rhodocyclales	206389|Rhodocyclales	NU	Pilus assembly protein PilO	pilO	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
k59_1791759_1	1537917.JU82_08010	1.84e-81	246.0	COG2885@1|root,COG2885@2|Bacteria,1MYBP@1224|Proteobacteria,42PIF@68525|delta/epsilon subdivisions,2YQ6W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,OmpA,Rick_17kDa_Anti
k59_1271530_2	159087.Daro_2175	2.8e-90	266.0	COG3157@1|root,COG3157@2|Bacteria,1R3V8@1224|Proteobacteria,2VP81@28216|Betaproteobacteria,2KXK1@206389|Rhodocyclales	206389|Rhodocyclales	S	Type VI secretion system effector, Hcp	-	-	-	ko:K11903	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	T6SS_HCP
k59_1204981_1	1249480.B649_02725	7.8e-50	162.0	COG1585@1|root,COG1585@2|Bacteria,1QAJG@1224|Proteobacteria,43AB2@68525|delta/epsilon subdivisions,2YQRB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	OU	Membrane protein implicated in regulation of membrane protease activity	-	-	-	ko:K07340	-	-	-	-	ko00000	-	-	-	NfeD
k59_265866_1	1537917.JU82_03505	3.53e-72	228.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,42MG3@68525|delta/epsilon subdivisions,2YMCB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	ABC-type transport system involved in resistance to organic solvents permease component	iamB	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE,STAS,STAS_2
k59_1151937_1	709032.Sulku_0547	2.55e-109	319.0	COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,42NWH@68525|delta/epsilon subdivisions,2YQPR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
k59_684440_1	159087.Daro_3662	5.07e-190	535.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,2VHQI@28216|Betaproteobacteria,2KUHQ@206389|Rhodocyclales	206389|Rhodocyclales	E	aminopeptidase	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
k59_417892_1	1537917.JU82_01045	1.81e-07	51.6	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,42NC6@68525|delta/epsilon subdivisions,2YMJV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
k59_417892_2	1249480.B649_05560	2.64e-105	307.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,42M8E@68525|delta/epsilon subdivisions,2YNXC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iIT341.HP0618	ADK
k59_417892_3	709032.Sulku_1000	5.92e-116	334.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,42M8E@68525|delta/epsilon subdivisions,2YPCE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
k59_594308_2	1249480.B649_05600	4.72e-106	320.0	COG0791@1|root,COG0791@2|Bacteria,1R45H@1224|Proteobacteria,42NS0@68525|delta/epsilon subdivisions,2YN06@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,N_NLPC_P60,Peptidase_M15_4,SH3_6,SH3_7
k59_1709438_1	563040.Saut_0151	3.53e-34	122.0	2EG4M@1|root,308R5@2|Bacteria,1QSJZ@1224|Proteobacteria,432VN@68525|delta/epsilon subdivisions,2YSQV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_65046_1	123214.PERMA_1839	1.34e-64	219.0	COG3303@1|root,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
k59_477469_1	269797.Mbar_A0034	6.5e-59	192.0	COG1089@1|root,arCOG01373@2157|Archaea,2XUVY@28890|Euryarchaeota,2N9AM@224756|Methanomicrobia	224756|Methanomicrobia	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
k59_1534656_2	709032.Sulku_1133	4.76e-89	271.0	29CAW@1|root,2ZZ9C@2|Bacteria,1Q5FH@1224|Proteobacteria,42Q2S@68525|delta/epsilon subdivisions,2YP18@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1181314_1	1537917.JU82_03415	5.98e-115	342.0	COG0446@1|root,COG0446@2|Bacteria,1PWV7@1224|Proteobacteria,42QCM@68525|delta/epsilon subdivisions,2YND4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COGs COG1252 NADH dehydrogenase FAD-containing subunit	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_1592294_1	1132855.KB913035_gene857	4.91e-07	50.1	COG0347@1|root,COG0347@2|Bacteria,1N32M@1224|Proteobacteria,2VUEY@28216|Betaproteobacteria,2KMXR@206350|Nitrosomonadales	206350|Nitrosomonadales	K	Belongs to the P(II) protein family	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
k59_1592294_2	1094755.MCO_00144	4.85e-27	113.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,2TQUZ@28211|Alphaproteobacteria,48TBE@772|Bartonellaceae	28211|Alphaproteobacteria	O	C-terminal, D2-small domain, of ClpB protein	clpA	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_417921_2	1537917.JU82_03985	1.19e-138	399.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,42MCP@68525|delta/epsilon subdivisions,2YMQE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
k59_594340_1	1165841.SULAR_06258	4.33e-114	345.0	COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,42N42@68525|delta/epsilon subdivisions,2YMNR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
k59_65061_1	709032.Sulku_1538	1.78e-38	131.0	2AJUV@1|root,31AHI@2|Bacteria,1Q5NQ@1224|Proteobacteria,431IN@68525|delta/epsilon subdivisions,2YSBH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_65061_2	1249480.B649_06795	1.95e-59	187.0	2BV3K@1|root,3187I@2|Bacteria,1PZXK@1224|Proteobacteria,430TM@68525|delta/epsilon subdivisions,2YS1S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1650891_1	1500890.JQNL01000001_gene1290	3.24e-20	95.1	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RMS3@1236|Gammaproteobacteria,1X3RQ@135614|Xanthomonadales	135614|Xanthomonadales	CH	hydroxylase	ubiH	-	-	ko:K03185	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04989,R08773	RC02670	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
k59_299621_1	1249480.B649_04475	3.26e-80	247.0	COG1672@1|root,COG1672@2|Bacteria,1PZGT@1224|Proteobacteria,42QN9@68525|delta/epsilon subdivisions,2YNKC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Archaea bacterial proteins of unknown function	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	DUF234
k59_241861_1	1537917.JU82_04350	2.31e-68	223.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,42MYN@68525|delta/epsilon subdivisions,2YMXA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	molybdopterin oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin,Molydop_binding
k59_769326_1	159087.Daro_0316	3.76e-135	401.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,2VI3Q@28216|Betaproteobacteria,2KUP0@206389|Rhodocyclales	206389|Rhodocyclales	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_417935_1	62928.azo1457	1.25e-35	133.0	COG0840@1|root,COG0840@2|Bacteria,1NJXF@1224|Proteobacteria,2VM8I@28216|Betaproteobacteria,2KUYK@206389|Rhodocyclales	206389|Rhodocyclales	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
k59_417935_2	1454004.AW11_00484	6.68e-09	55.8	COG4446@1|root,COG4446@2|Bacteria,1N7IZ@1224|Proteobacteria,2VSQW@28216|Betaproteobacteria,1KQVE@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF1499)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1499
k59_1356807_1	159087.Daro_4201	5.92e-14	70.5	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,2VHIA@28216|Betaproteobacteria,2KUBX@206389|Rhodocyclales	206389|Rhodocyclales	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
k59_1356807_2	545264.KB898744_gene2267	4.1e-13	67.0	COG0594@1|root,COG0594@2|Bacteria,1MZQE@1224|Proteobacteria,1S90M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031974,GO:0031981,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
k59_1123318_1	572477.Alvin_0389	9.74e-200	568.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,1RM92@1236|Gammaproteobacteria,1WWJ8@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
k59_1474891_1	395494.Galf_0315	1.29e-68	223.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2VHAN@28216|Betaproteobacteria,44V3U@713636|Nitrosomonadales	28216|Betaproteobacteria	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	msbA	-	-	ko:K02021,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21	-	-	ABC_membrane,ABC_tran
k59_829618_1	159087.Daro_3667	8.48e-71	227.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,2VJPX@28216|Betaproteobacteria,2KUUV@206389|Rhodocyclales	206389|Rhodocyclales	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
k59_829618_2	159087.Daro_3666	1.07e-44	145.0	COG2901@1|root,COG2901@2|Bacteria,1N7MJ@1224|Proteobacteria,2VVQK@28216|Betaproteobacteria,2KX0P@206389|Rhodocyclales	206389|Rhodocyclales	KL	Belongs to the transcriptional regulatory Fis family	-	-	-	ko:K03557	ko05111,map05111	-	-	-	ko00000,ko00001,ko03000,ko03036,ko03400	-	-	-	HTH_8
k59_829618_3	159087.Daro_3665	3.66e-34	125.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,2VHBP@28216|Betaproteobacteria,2KUU1@206389|Rhodocyclales	206389|Rhodocyclales	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dusB	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
k59_1416502_1	1249480.B649_05995	4.36e-122	358.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,42N8U@68525|delta/epsilon subdivisions,2YMG9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0026	Citrate_synt
k59_594380_1	1112274.KI911560_gene2242	3.22e-27	103.0	2EP1T@1|root,33GNN@2|Bacteria,1NJTG@1224|Proteobacteria,2VYI0@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_710290_1	1249480.B649_10290	1.34e-51	173.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42MNF@68525|delta/epsilon subdivisions,2YMW2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_710290_2	709032.Sulku_2177	2.34e-23	94.0	COG0494@1|root,COG0494@2|Bacteria,1QSQG@1224|Proteobacteria,42RR5@68525|delta/epsilon subdivisions,2YP9Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Nudix domain	-	-	3.6.1.45	ko:K08077	-	-	-	-	ko00000,ko01000	-	-	-	NUDIX
k59_477550_1	1537917.JU82_02080	1.27e-79	263.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,42NKH@68525|delta/epsilon subdivisions,2YMVS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the helicase family. UvrD subfamily	addA	-	3.1.11.5	ko:K03582	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C
k59_65097_1	1537917.JU82_08195	6.67e-85	255.0	COG1451@1|root,COG1451@2|Bacteria,1MXZU@1224|Proteobacteria,42V1Y@68525|delta/epsilon subdivisions,2YQDY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	hmm pf01863	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
k59_1768215_1	709032.Sulku_2435	3.69e-46	150.0	2E63D@1|root,32SZ8@2|Bacteria,1N3BN@1224|Proteobacteria,42WAA@68525|delta/epsilon subdivisions,2YQCN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Is required to sustain N(2)-dependent growth in the presence of low levels of carbon monoxide (CO). Probably acts by protecting the N(2) fixation ability of the nitrogenase complex, which is inactivated in the presence of CO	cowN	-	-	ko:K21694	-	-	-	-	ko00000	-	-	-	-
k59_1768215_2	1249480.B649_11290	3.59e-66	210.0	COG2220@1|root,COG2220@2|Bacteria,1MV20@1224|Proteobacteria,42QPP@68525|delta/epsilon subdivisions,2YP9R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
k59_299659_1	1537917.JU82_01580	3.29e-48	157.0	COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,42RRU@68525|delta/epsilon subdivisions,2YP7A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	acetolactate synthase	ilvH	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
k59_299659_2	1537917.JU82_01575	4.31e-77	244.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,42M1X@68525|delta/epsilon subdivisions,2YMQ9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	acetolactate synthase	ilvI	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_887783_1	1249480.B649_00030	5.64e-93	290.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria	1224|Proteobacteria	P	Receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_654434_1	1249480.B649_02850	2.49e-106	311.0	COG2733@1|root,COG2733@2|Bacteria,1R4JT@1224|Proteobacteria,42RK1@68525|delta/epsilon subdivisions,2YPBZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_537061_1	62928.azo0499	2.69e-12	66.6	COG0834@1|root,COG0834@2|Bacteria,1MWDK@1224|Proteobacteria,2VIQA@28216|Betaproteobacteria,2KX8J@206389|Rhodocyclales	206389|Rhodocyclales	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_3
k59_537061_2	1266925.JHVX01000002_gene742	1.55e-13	69.7	COG2191@1|root,COG2191@2|Bacteria,1RD60@1224|Proteobacteria,2VR8B@28216|Betaproteobacteria,371NU@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Formylmethanofuran dehydrogenase, subunit e	-	-	-	-	-	-	-	-	-	-	-	-	FmdE
k59_1241382_1	387093.SUN_0805	2.5e-116	353.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42MCY@68525|delta/epsilon subdivisions,2YMB3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB1	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
k59_477571_1	1537917.JU82_01670	9.97e-104	332.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,43DMZ@68525|delta/epsilon subdivisions,2YMMS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_1356861_1	1244528.CFT03427_0921	0.000288	48.1	COG2982@1|root,COG3164@1|root,COG2982@2|Bacteria,COG3164@2|Bacteria,1QA6E@1224|Proteobacteria,42NCN@68525|delta/epsilon subdivisions,2YM89@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_1,DUF3971
k59_1356861_2	1249480.B649_06135	3.17e-82	252.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,42MPA@68525|delta/epsilon subdivisions,2YMKT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
k59_417996_1	1134912.AJTV01000014_gene238	1.5e-20	95.5	COG1752@1|root,COG1752@2|Bacteria,1MUI6@1224|Proteobacteria,2U3P9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
k59_299685_1	1172190.M947_09270	3.41e-43	148.0	COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,42MJK@68525|delta/epsilon subdivisions,2YMV3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0400	LYTB
k59_299685_2	709032.Sulku_0884	2.13e-164	473.0	COG0539@1|root,COG2183@1|root,COG0539@2|Bacteria,COG2183@2|Bacteria,1MVAV@1224|Proteobacteria,42M29@68525|delta/epsilon subdivisions,2YMBM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	ribosomal protein S1	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
k59_1592385_1	1249480.B649_00865	2.91e-69	214.0	COG0035@1|root,COG0035@2|Bacteria,1MV4N@1224|Proteobacteria,42NNR@68525|delta/epsilon subdivisions,2YMH0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
k59_1650994_1	709032.Sulku_2284	5.27e-72	222.0	COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,42R9F@68525|delta/epsilon subdivisions,2YNVJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
k59_1534781_1	749222.Nitsa_0960	1.6e-125	385.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2YNMM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.6,3.6.3.8	ko:K01535,ko:K01537	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.3.2,3.A.3.3	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
k59_1592401_1	1249480.B649_11735	7.44e-35	128.0	COG2855@1|root,COG2855@2|Bacteria,1MVIP@1224|Proteobacteria,42P59@68525|delta/epsilon subdivisions,2YMPJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the UPF0324 family	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
k59_1592401_2	709032.Sulku_2534	3.16e-25	105.0	COG3164@1|root,COG3164@2|Bacteria,1QUYX@1224|Proteobacteria,43CES@68525|delta/epsilon subdivisions,2YTC9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
k59_1065425_1	666681.M301_2375	3.67e-98	304.0	COG3064@1|root,COG4656@1|root,COG3064@2|Bacteria,COG4656@2|Bacteria,1PJVF@1224|Proteobacteria,2VM4P@28216|Betaproteobacteria,2KNEK@206350|Nitrosomonadales	206350|Nitrosomonadales	CM	Part of a membrane complex involved in electron transport	-	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,Fer4_8,RnfC_N,SLBB
k59_889493_1	159087.Daro_0770	6.39e-33	125.0	COG1157@1|root,COG1157@2|Bacteria,1MUH6@1224|Proteobacteria,2VHQ5@28216|Betaproteobacteria,2KUH3@206389|Rhodocyclales	206389|Rhodocyclales	NU	ATPase FliI YscN family	fliI	-	3.6.3.14	ko:K02412	ko02040,map02040	-	-	-	ko00000,ko00001,ko01000,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	ATP-synt_ab
k59_889493_2	159087.Daro_0771	4.26e-43	147.0	COG1317@1|root,COG1317@2|Bacteria,1NMQE@1224|Proteobacteria,2VSQ0@28216|Betaproteobacteria,2KWS2@206389|Rhodocyclales	206389|Rhodocyclales	N	Flagellar assembly protein FliH	-	-	-	ko:K02411	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliH
k59_10096_2	159087.Daro_0213	1.95e-114	329.0	COG3168@1|root,COG3168@2|Bacteria,1RI6V@1224|Proteobacteria,2VSVR@28216|Betaproteobacteria,2KWK4@206389|Rhodocyclales	206389|Rhodocyclales	NU	pilus assembly protein PilP	pilP	-	-	ko:K02665	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilP
k59_10096_3	159087.Daro_0212	2.07e-35	126.0	COG3167@1|root,COG3167@2|Bacteria,1RBGW@1224|Proteobacteria,2VH68@28216|Betaproteobacteria,2KW2A@206389|Rhodocyclales	206389|Rhodocyclales	NU	Pilus assembly protein PilO	pilO	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
k59_419588_1	709032.Sulku_2593	5.24e-135	392.0	COG3256@1|root,COG3256@2|Bacteria,1MVT1@1224|Proteobacteria,42NBM@68525|delta/epsilon subdivisions,2YMKZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Nitric oxide reductase	norZ	-	1.7.2.5	ko:K04561	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002,ko01000	3.D.4.10	-	-	COX1
k59_1243360_1	159087.Daro_0512	2.17e-94	276.0	COG1522@1|root,COG1522@2|Bacteria,1MX7R@1224|Proteobacteria,2VQ1S@28216|Betaproteobacteria,2KW4D@206389|Rhodocyclales	206389|Rhodocyclales	K	transcriptional	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24
k59_596212_1	1249480.B649_11195	2.04e-29	105.0	COG1977@1|root,COG1977@2|Bacteria,1Q2EI@1224|Proteobacteria,42VIE@68525|delta/epsilon subdivisions,2YQ69@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	molybdopterin converting factor	moaD	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
k59_596212_2	1537917.JU82_02485	8.64e-107	313.0	COG1427@1|root,COG1427@2|Bacteria,1RCS0@1224|Proteobacteria,42MJZ@68525|delta/epsilon subdivisions,2YN8T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
k59_1418459_1	709032.Sulku_1352	7.81e-282	770.0	COG1748@1|root,COG1748@2|Bacteria,1NIU2@1224|Proteobacteria,42MHS@68525|delta/epsilon subdivisions,2YM99@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Saccharopine dehydrogenase	LYS1	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
k59_831449_1	1265507.KB899636_gene1506	3.38e-08	55.1	COG4968@1|root,COG4968@2|Bacteria,1R4X4@1224|Proteobacteria,1T22U@1236|Gammaproteobacteria,1Y5K3@135624|Aeromonadales	135624|Aeromonadales	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K10925	ko05111,map05111	-	-	-	ko00000,ko00001,ko02044	-	-	-	N_methyl
k59_831449_2	1101195.Meth11DRAFT_0623	6.15e-31	114.0	COG2165@1|root,COG2165@2|Bacteria,1N7HN@1224|Proteobacteria,2VV9M@28216|Betaproteobacteria,2KNGV@206350|Nitrosomonadales	206350|Nitrosomonadales	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K10924	ko05111,map05111	-	-	-	ko00000,ko00001,ko02044	-	-	-	N_methyl
k59_66531_1	709032.Sulku_0596	1.47e-255	703.0	COG2041@1|root,COG2041@2|Bacteria,1MX9E@1224|Proteobacteria,42QKD@68525|delta/epsilon subdivisions,2YNHF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Sulfite dehydrogenase (Cytochrome) subunit SorA apoprotein	sorA	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Mo-co_dimer,Oxidored_molyb
k59_1418466_1	709032.Sulku_2491	6.37e-125	382.0	COG0243@1|root,COG0243@2|Bacteria,1NSXR@1224|Proteobacteria,43BQI@68525|delta/epsilon subdivisions,2YRHF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	ko:K17050	-	-	-	-	ko00000,ko02000	5.A.3.8	-	-	Molybdopterin,Molydop_binding
k59_1243383_2	1537917.JU82_04570	1.72e-71	216.0	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,42TSD@68525|delta/epsilon subdivisions,2YPGD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
k59_243680_1	1165841.SULAR_03772	7.92e-37	140.0	COG1449@1|root,COG1449@2|Bacteria,1Q9WP@1224|Proteobacteria,42M42@68525|delta/epsilon subdivisions,2YMAK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	2.4.1.25	ko:K22451	ko00500,map00500	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH57	-	DUF1925,DUF1926,Glyco_hydro_57
k59_243680_2	563040.Saut_0475	0.00019	43.1	COG1085@1|root,COG1085@2|Bacteria,1MU3E@1224|Proteobacteria,42MP4@68525|delta/epsilon subdivisions,2YNIF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1085 Galactose-1-phosphate uridylyltransferase	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
k59_127186_1	1249480.B649_06155	2.43e-54	193.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YN16@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	GGDEF EAL family protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,NIT,PAS_3,PAS_9
k59_419626_1	709032.Sulku_0739	4.19e-61	209.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2YN6Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DNA mismatch repair MutS family	-	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_III,MutS_V
k59_1299958_1	709032.Sulku_0386	4.38e-42	142.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,42S1J@68525|delta/epsilon subdivisions,2YT8I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k59_1299958_2	709032.Sulku_0387	7.31e-105	312.0	29W5U@1|root,30HQY@2|Bacteria,1QUJN@1224|Proteobacteria,42NUV@68525|delta/epsilon subdivisions,2YNFP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_183974_1	1304883.KI912532_gene1717	7.32e-72	231.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,2VIE0@28216|Betaproteobacteria,2KUDK@206389|Rhodocyclales	206389|Rhodocyclales	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_5
k59_1243419_1	1163730.FFONT_0771	5.16e-38	143.0	COG0423@1|root,arCOG00405@2157|Archaea,2XPSF@28889|Crenarchaeota	28889|Crenarchaeota	J	PFAM tRNA synthetase, class II (G, H, P and S)	glyS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
k59_1065508_1	460265.Mnod_0281	4.51e-29	120.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2U3XH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF839,HemolysinCabind
k59_831510_1	1158294.JOMI01000002_gene3136	9.95e-32	122.0	COG1496@1|root,COG1496@2|Bacteria,4NM9H@976|Bacteroidetes,2FN7X@200643|Bacteroidia	976|Bacteroidetes	S	Belongs to the multicopper oxidase YfiH RL5 family	-	GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0046983,GO:0055114	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
k59_1358429_1	1121434.AULY01000006_gene271	1.05e-15	77.8	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,43BSG@68525|delta/epsilon subdivisions,2WTKV@28221|Deltaproteobacteria,2MGYE@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
k59_66571_1	522306.CAP2UW1_0521	3.66e-30	124.0	COG0840@1|root,COG2703@1|root,COG4564@1|root,COG0840@2|Bacteria,COG2703@2|Bacteria,COG4564@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria	28216|Betaproteobacteria	NT	chemotaxis	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	Hemerythrin,MCPsignal,dCache_2
k59_360334_1	387093.SUN_0064	2.18e-36	124.0	COG0268@1|root,COG0268@2|Bacteria,1NITA@1224|Proteobacteria,42V4U@68525|delta/epsilon subdivisions,2YPUG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
k59_360334_2	1165841.SULAR_10664	3.78e-54	179.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,42NA3@68525|delta/epsilon subdivisions,2YMD9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k59_656316_1	1206732.BAGD01000277_gene6275	6.08e-23	95.5	COG0022@1|root,COG0022@2|Bacteria,2GKFE@201174|Actinobacteria,4FVDH@85025|Nocardiaceae	201174|Actinobacteria	C	Dehydrogenase	-	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
k59_656316_2	1121861.KB899911_gene1300	3.2e-36	133.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2TRW0@28211|Alphaproteobacteria,2JV13@204441|Rhodospirillales	204441|Rhodospirillales	C	Dehydrogenase E1 component	-	-	-	-	-	-	-	-	-	-	-	-	E1_dh
k59_949238_1	1562701.BBOF01000081_gene249	3.88e-40	150.0	28MS5@1|root,2ZB0J@2|Bacteria,1PTV9@1224|Proteobacteria,2VMIH@28216|Betaproteobacteria,1KD2P@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1446728_1	1249480.B649_06600	2.04e-104	329.0	COG2199@1|root,COG2200@1|root,COG3287@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,COG3287@2|Bacteria,1NQKX@1224|Proteobacteria,43DAG@68525|delta/epsilon subdivisions,2YTHK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,FIST,FIST_C,GGDEF,PAS_9
k59_1151507_1	1249480.B649_03140	5.79e-87	269.0	COG0739@1|root,COG0739@2|Bacteria,1N19D@1224|Proteobacteria,42SMK@68525|delta/epsilon subdivisions,2YTS0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_504840_2	709032.Sulku_1131	3.29e-92	271.0	COG1576@1|root,COG1576@2|Bacteria,1N7WB@1224|Proteobacteria,42V41@68525|delta/epsilon subdivisions,2YP43@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
k59_28033_1	1304883.KI912532_gene1075	1.34e-19	89.0	COG4772@1|root,COG4772@2|Bacteria,1QVCH@1224|Proteobacteria,2WGQ6@28216|Betaproteobacteria,2KVN0@206389|Rhodocyclales	206389|Rhodocyclales	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_28033_2	1249480.B649_01930	1.42e-14	72.4	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1RGCV@1224|Proteobacteria,43CEF@68525|delta/epsilon subdivisions,2YTC1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_1674786_1	522306.CAP2UW1_2723	1.01e-43	149.0	29V5H@1|root,30GJ5@2|Bacteria,1PHC8@1224|Proteobacteria,2VRT9@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3617)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3617
k59_1674786_2	640081.Dsui_1956	1.62e-05	46.2	COG0607@1|root,COG0607@2|Bacteria,1N5D7@1224|Proteobacteria,2VVDJ@28216|Betaproteobacteria,2KXM3@206389|Rhodocyclales	206389|Rhodocyclales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_1857658_1	709032.Sulku_0161	2.36e-18	85.1	COG0154@1|root,COG0154@2|Bacteria,1MWRI@1224|Proteobacteria,42SYU@68525|delta/epsilon subdivisions,2YR2Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
k59_1857658_2	1249480.B649_00665	1.09e-85	261.0	COG0037@1|root,COG0037@2|Bacteria,1NKHX@1224|Proteobacteria,42Q26@68525|delta/epsilon subdivisions,2YT3T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	TIGRFAM N-acetyl sugar amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1089272_1	709032.Sulku_0549	3.5e-22	98.2	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,42NDS@68525|delta/epsilon subdivisions,2YN0K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	DNA recombination protein	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
k59_1446760_1	159087.Daro_3531	2.55e-47	164.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,2VH1I@28216|Betaproteobacteria,2KUSA@206389|Rhodocyclales	206389|Rhodocyclales	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
k59_1446760_2	159087.Daro_3530	1.07e-53	176.0	COG4535@1|root,COG4535@2|Bacteria,1QTU8@1224|Proteobacteria,2VIU8@28216|Betaproteobacteria,2KV4Z@206389|Rhodocyclales	206389|Rhodocyclales	P	Mg2 and Co2 transporter CorC	-	-	-	ko:K06189	-	-	-	-	ko00000,ko02000	9.A.40.1.2	-	-	CBS,CorC_HlyC
k59_974428_1	758.BBIX01000009_gene2167	7.35e-15	79.7	COG4104@1|root,COG4104@2|Bacteria,1N6WE@1224|Proteobacteria,1RR6E@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Uncharacterized alpha/beta hydrolase domain (DUF2235)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2235,PAAR_motif
k59_1564155_2	709032.Sulku_1880	1.18e-46	156.0	COG3218@1|root,COG3218@2|Bacteria,1NNSH@1224|Proteobacteria,42X3M@68525|delta/epsilon subdivisions,2YQQ8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	transport system auxiliary component	-	-	-	ko:K18480	-	M00669	-	-	ko00000,ko00002,ko02000	3.A.1.27.1	-	-	ABC_trans_aux
k59_207989_1	796620.VIBC2010_03170	3.33e-27	112.0	COG2199@1|root,COG2204@1|root,COG2204@2|Bacteria,COG3706@2|Bacteria,1MXBG@1224|Proteobacteria,1RNJA@1236|Gammaproteobacteria,1XSJA@135623|Vibrionales	135623|Vibrionales	T	COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
k59_1733361_1	1249480.B649_03985	3.24e-22	95.9	2AN97@1|root,32J0R@2|Bacteria,1PCA3@1224|Proteobacteria,42T7U@68525|delta/epsilon subdivisions,2YPPF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Flg_hook
k59_1733361_2	1249480.B649_03990	5.58e-87	265.0	COG2230@1|root,COG2230@2|Bacteria	2|Bacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	DUF938,Methyltransf_23,Methyltransf_25,Methyltransf_31
k59_1564173_1	709032.Sulku_0635	2.92e-167	482.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42P4R@68525|delta/epsilon subdivisions,2YM92@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	DUF3365,MCPsignal
k59_85646_1	666681.M301_1662	1.19e-92	290.0	COG2202@1|root,COG3852@1|root,COG4191@1|root,COG2202@2|Bacteria,COG3852@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VI6T@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_9
k59_684073_1	1537917.JU82_10810	5.85e-33	125.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,42NGG@68525|delta/epsilon subdivisions,2YN35@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Nucleotidyltransferase DNA polymerase involved in DNA repair	dinP	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
k59_684073_2	1537917.JU82_10805	7.55e-36	130.0	COG1672@1|root,COG1672@2|Bacteria,1PMVJ@1224|Proteobacteria,42PCP@68525|delta/epsilon subdivisions,2YNZF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM Archaea bacterial proteins of	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	DUF234
k59_85672_1	1249480.B649_07290	9.83e-178	498.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,42M2J@68525|delta/epsilon subdivisions,2YN8F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	frdB	-	1.3.5.1,1.3.5.4	ko:K00240,ko:K00245	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0191	Fer2_3,Fer4_8
k59_380400_1	279714.FuraDRAFT_3761	1.24e-18	85.9	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,2VJTH@28216|Betaproteobacteria,2KPDI@206351|Neisseriales	206351|Neisseriales	M	Transporter, small conductance mechanosensitive ion channel MscS family protein	aefA	-	-	-	-	-	-	-	-	-	-	-	MS_channel
k59_380400_2	946483.Cenrod_0165	1.48e-15	73.6	COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,2VSE7@28216|Betaproteobacteria,4AEIH@80864|Comamonadaceae	28216|Betaproteobacteria	J	PFAM Class I peptide chain release factor	yaeJ	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
k59_1674845_1	1537917.JU82_02650	2.93e-94	286.0	COG3303@1|root,COG3303@2|Bacteria,1QUJG@1224|Proteobacteria,42RGW@68525|delta/epsilon subdivisions,2YMPH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
k59_796521_1	387093.SUN_0007	2.13e-31	119.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,42M5V@68525|delta/epsilon subdivisions,2YM81@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Cysteine desulfurase	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
k59_796521_2	1165841.SULAR_08502	4.3e-197	550.0	COG0694@1|root,COG0822@1|root,COG0694@2|Bacteria,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,42MT6@68525|delta/epsilon subdivisions,2YMXY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CO	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins	iscU	-	-	ko:K13819	-	-	-	-	ko00000	-	-	-	Fer2_BFD,NifU,NifU_N
k59_684090_1	159087.Daro_3735	2.39e-60	199.0	COG4262@1|root,COG4262@2|Bacteria,1QTYC@1224|Proteobacteria,2VK9Z@28216|Betaproteobacteria,2KVY0@206389|Rhodocyclales	206389|Rhodocyclales	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
k59_684090_2	159087.Daro_3734	3.48e-34	129.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,PAS_3,PAS_4,PAS_9,dCache_1
k59_686853_2	1249480.B649_11405	4.71e-39	135.0	COG0226@1|root,COG0226@2|Bacteria,1N19C@1224|Proteobacteria,42VP7@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	COG0226 ABC-type phosphate transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	PBP_like_2
k59_686853_3	1249480.B649_11400	2.03e-27	108.0	29Y2F@1|root,30JVD@2|Bacteria,1RAWX@1224|Proteobacteria,4300B@68525|delta/epsilon subdivisions,2YRWY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_729728_1	398767.Glov_1549	1.77e-38	147.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,42NK9@68525|delta/epsilon subdivisions,2WJUY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_9,Response_reg
k59_1274001_1	1249480.B649_04630	1.51e-119	346.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,42S2A@68525|delta/epsilon subdivisions,2YP5V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NOU	Peptidase A24	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
k59_1618475_1	358220.C380_06160	4.65e-96	281.0	COG4454@1|root,COG4454@2|Bacteria,1R91G@1224|Proteobacteria,2VSS8@28216|Betaproteobacteria,4AESG@80864|Comamonadaceae	28216|Betaproteobacteria	P	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
k59_267857_1	349965.yinte0001_13410	3.33e-63	219.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,1RM9A@1236|Gammaproteobacteria,41F34@629|Yersinia	1236|Gammaproteobacteria	D	cell division protein	ftsK	GO:0000920,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006950,GO:0006970,GO:0007059,GO:0008094,GO:0008150,GO:0009628,GO:0009651,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0015616,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033676,GO:0042221,GO:0042623,GO:0042802,GO:0043085,GO:0043565,GO:0044093,GO:0044425,GO:0044459,GO:0044464,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051301,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070887,GO:0071236,GO:0071944,GO:0080090,GO:0097159,GO:0140097,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
k59_913432_1	90814.KL370891_gene1879	1.07e-32	120.0	2EQTE@1|root,33ID4@2|Bacteria,1RKB7@1224|Proteobacteria,1S6DN@1236|Gammaproteobacteria,462RN@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_913432_2	717772.THIAE_01670	5.88e-57	189.0	COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,1RPGM@1236|Gammaproteobacteria,460YR@72273|Thiotrichales	72273|Thiotrichales	IQ	FolM Alternative dihydrofolate reductase 1	-	-	1.5.1.3,1.5.1.50	ko:K13938	ko00670,ko00790,ko01100,map00670,map00790,map01100	-	R00936,R00939,R11019	RC00109,RC03327	ko00000,ko00001,ko01000	-	-	-	adh_short,adh_short_C2
k59_799705_1	709032.Sulku_0886	1.57e-122	363.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,42M1C@68525|delta/epsilon subdivisions,2YMF3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
k59_799715_1	709032.Sulku_0943	3.26e-150	434.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,42MXF@68525|delta/epsilon subdivisions,2YMJ8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Mur ligase middle domain	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
k59_1092122_1	1249480.B649_08290	6.62e-148	426.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,42KZA@68525|delta/epsilon subdivisions,2YMA9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
k59_267924_1	1537917.JU82_04540	3.91e-40	134.0	2BJZK@1|root,32ECD@2|Bacteria,1QDIV@1224|Proteobacteria,433KD@68525|delta/epsilon subdivisions,2YSRX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_267924_2	1537917.JU82_04535	4.12e-42	149.0	COG0477@1|root,COG2814@2|Bacteria,1QRUM@1224|Proteobacteria,42MFJ@68525|delta/epsilon subdivisions,2YMW9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EGP	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_913493_1	395019.Bmul_6262	1.17e-12	73.6	COG4974@1|root,COG4974@2|Bacteria,1PZTE@1224|Proteobacteria,2VMKS@28216|Betaproteobacteria,1KG4G@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3701,Phage_integrase
k59_729820_1	159087.Daro_4048	3.35e-90	285.0	COG5001@1|root,COG5002@1|root,COG5001@2|Bacteria,COG5002@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KV9J@206389|Rhodocyclales	206389|Rhodocyclales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_4,PAS_9
k59_1677213_1	62928.azo2446	1.53e-116	350.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,2VIKD@28216|Betaproteobacteria,2KUEW@206389|Rhodocyclales	206389|Rhodocyclales	K	Fis family transcriptional regulator	poxR	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat,V4R,XylR_N
k59_507366_1	1537917.JU82_06725	2.29e-97	291.0	COG0618@1|root,COG0618@2|Bacteria,1RADZ@1224|Proteobacteria,43DQA@68525|delta/epsilon subdivisions,2YT8A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	DHH family	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
k59_1041633_1	876269.ARWA01000001_gene157	2.79e-20	91.7	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2TQQM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	response regulator containing a CheY-like receiver domain and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Reg_prop,dCache_1
k59_1384503_1	709032.Sulku_0881	4.55e-119	363.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2YMAI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k59_211062_1	1165841.SULAR_02813	3.67e-57	188.0	COG0108@1|root,COG0108@2|Bacteria,1MU8P@1224|Proteobacteria,42N1C@68525|delta/epsilon subdivisions,2YMUA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
k59_267972_1	1304883.KI912532_gene1697	1.15e-07	49.3	COG0607@1|root,32YCZ@2|Bacteria,1N6NN@1224|Proteobacteria,2VVV9@28216|Betaproteobacteria,2KX5R@206389|Rhodocyclales	206389|Rhodocyclales	P	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
k59_1041652_1	314345.SPV1_10019	1.41e-29	121.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_4
k59_913545_1	159087.Daro_1501	1.24e-250	693.0	COG2710@1|root,COG2710@2|Bacteria,1MWAJ@1224|Proteobacteria,2VJ11@28216|Betaproteobacteria,2KVBY@206389|Rhodocyclales	206389|Rhodocyclales	C	Nitrogenase component 1 type Oxidoreductase	-	-	-	ko:K02587	-	-	-	-	ko00000	-	-	-	Oxidored_nitro
k59_211086_1	709032.Sulku_0723	5.48e-67	218.0	COG4972@1|root,COG4972@2|Bacteria,1QA6M@1224|Proteobacteria,42NDB@68525|delta/epsilon subdivisions,2YMP2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Pilus assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_211086_2	709032.Sulku_0722	7.37e-54	174.0	2AIDI@1|root,31TAR@2|Bacteria,1QR0P@1224|Proteobacteria,42TWA@68525|delta/epsilon subdivisions,2YSYQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PilO
k59_687054_1	1249480.B649_04825	6.2e-83	272.0	COG0755@1|root,COG1333@1|root,COG0755@2|Bacteria,COG1333@2|Bacteria,1RG0A@1224|Proteobacteria,42N37@68525|delta/epsilon subdivisions,2YMXW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Cytochrome c biogenesis protein	ccsBA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
k59_570505_1	1304883.KI912532_gene308	1.12e-43	145.0	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,2VU5R@28216|Betaproteobacteria,2KWK1@206389|Rhodocyclales	206389|Rhodocyclales	L	COG0350 Methylated DNA-protein cysteine methyltransferase	-	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
k59_570505_2	159087.Daro_0537	2.95e-59	191.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,2VIHD@28216|Betaproteobacteria,2KUYI@206389|Rhodocyclales	206389|Rhodocyclales	D	recombinase XerD	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_155520_1	1537917.JU82_04475	1.84e-102	303.0	COG0171@1|root,COG0171@2|Bacteria,1MU9U@1224|Proteobacteria,42N86@68525|delta/epsilon subdivisions,2YNG2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source	nadE	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
k59_687075_1	1249480.B649_03965	1.45e-186	540.0	COG1033@1|root,COG1033@2|Bacteria	2|Bacteria	S	growth of symbiont in host cell	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_1735780_1	1229172.JQFA01000002_gene3998	2.56e-46	171.0	COG2199@1|root,COG2202@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,1FZWU@1117|Cyanobacteria,1H8MG@1150|Oscillatoriales	1117|Cyanobacteria	T	GGDEF domain'	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,GAF_2,GGDEF,PAS_3,PAS_4,PAS_8,PAS_9
k59_320775_1	373994.Riv7116_6565	5.37e-49	167.0	COG0668@1|root,COG0668@2|Bacteria,1G06A@1117|Cyanobacteria,1HS0E@1161|Nostocales	1117|Cyanobacteria	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
k59_913585_1	317025.Tcr_1957	1.38e-96	316.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,45ZWV@72273|Thiotrichales	72273|Thiotrichales	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_1794020_1	1517681.HW45_21685	9.7e-31	124.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,1RNYW@1236|Gammaproteobacteria,1XT9K@135623|Vibrionales	135623|Vibrionales	OU	signal peptide peptidase	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
k59_1860804_1	159087.Daro_3718	2.81e-106	316.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,2VHK7@28216|Betaproteobacteria,2KVC3@206389|Rhodocyclales	206389|Rhodocyclales	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
k59_1567240_1	1304883.KI912532_gene2786	3.43e-45	154.0	COG0697@1|root,COG0697@2|Bacteria,1MWSU@1224|Proteobacteria,2VHP3@28216|Betaproteobacteria,2KUCN@206389|Rhodocyclales	206389|Rhodocyclales	EG	Solute carrier family 35	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_1567240_2	159087.Daro_2829	1.25e-51	170.0	COG3228@1|root,COG3228@2|Bacteria,1RAHF@1224|Proteobacteria,2VJTJ@28216|Betaproteobacteria,2KVI8@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the MtfA family	-	-	-	ko:K09933	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_M90
k59_383024_1	1537917.JU82_02540	1.71e-197	555.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,42M0V@68525|delta/epsilon subdivisions,2YMAY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Glycolate oxidase subunit	glcD	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
k59_977616_1	159087.Daro_4108	6.81e-68	211.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,2VHR5@28216|Betaproteobacteria,2KVA0@206389|Rhodocyclales	206389|Rhodocyclales	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
k59_977616_2	159087.Daro_4107	4.96e-24	93.6	COG3312@1|root,COG3312@2|Bacteria	2|Bacteria	C	ATP synthase I chain	atpI	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0044769,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	iSSON_1240.SSON_3880	ATP-synt_I
k59_1567262_2	1537917.JU82_02085	1.13e-31	122.0	COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,1QUIU@1224|Proteobacteria,42M7I@68525|delta/epsilon subdivisions,2YMX0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG3893 inactivated superfamily I helicase	addB	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
k59_977627_1	1537917.JU82_03860	2.05e-56	181.0	COG1926@1|root,COG1926@2|Bacteria,1RAG8@1224|Proteobacteria,42N60@68525|delta/epsilon subdivisions,2YMCU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	phosphoribosyltransferase	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
k59_977627_2	1537917.JU82_03855	1.13e-31	120.0	COG1463@1|root,COG1463@2|Bacteria,1RFFS@1224|Proteobacteria,42P4P@68525|delta/epsilon subdivisions,2YNNZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
k59_1449978_1	272560.BPSL2429	6.17e-68	221.0	COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,2VI4M@28216|Betaproteobacteria,1K0ZU@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
k59_268083_1	395494.Galf_2224	1.35e-37	129.0	COG2197@1|root,COG2197@2|Bacteria,1N7EG@1224|Proteobacteria	1224|Proteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_268083_2	1537917.JU82_01455	9.58e-40	145.0	COG2206@1|root,COG2206@2|Bacteria,1R53C@1224|Proteobacteria,42R7P@68525|delta/epsilon subdivisions,2YPRS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
k59_1735851_2	317025.Tcr_0042	1.52e-41	144.0	28M4C@1|root,2ZAIA@2|Bacteria,1R67D@1224|Proteobacteria,1RQQQ@1236|Gammaproteobacteria,460BT@72273|Thiotrichales	72273|Thiotrichales	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
k59_1274361_1	580332.Slit_0202	1.52e-54	172.0	2C2BQ@1|root,32VU6@2|Bacteria,1N1M0@1224|Proteobacteria,2VUD4@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
k59_211241_1	1249480.B649_03350	6.38e-88	261.0	COG0454@1|root,COG0456@2|Bacteria,1NPCX@1224|Proteobacteria,42ZWJ@68525|delta/epsilon subdivisions,2YRWX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_7
k59_1450079_1	1249480.B649_00255	2.37e-73	226.0	COG1843@1|root,COG1843@2|Bacteria,1PQS2@1224|Proteobacteria,42TAQ@68525|delta/epsilon subdivisions,2YPFZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Required for flagellar hook formation. May act as a scaffolding protein	flgD	-	-	ko:K02389	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgD,FlgD_ig
k59_1450079_2	1249480.B649_00250	1.42e-124	369.0	COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,42MPN@68525|delta/epsilon subdivisions,2YMHV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Flagellar basal body protein	flgE	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bb_rod,Flg_bbr_C
k59_687259_2	1118060.CAGZ01000025_gene862	1.25e-14	80.9	COG2265@1|root,COG2265@2|Bacteria,2GIR3@201174|Actinobacteria,4CUDT@84998|Coriobacteriia	84998|Coriobacteriia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
k59_913728_1	159087.Daro_1767	1.15e-120	348.0	COG2186@1|root,COG2186@2|Bacteria,1MUP9@1224|Proteobacteria,2VQ0Q@28216|Betaproteobacteria,2KW6U@206389|Rhodocyclales	206389|Rhodocyclales	K	COG2186 Transcriptional regulators	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
k59_1057311_1	1165841.SULAR_07208	2.84e-102	311.0	COG0658@1|root,COG0658@2|Bacteria,1PY6P@1224|Proteobacteria,42NU2@68525|delta/epsilon subdivisions,2YME0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Competence protein	comE	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence
k59_1644451_1	583345.Mmol_1880	2.61e-34	120.0	COG4391@1|root,COG4391@2|Bacteria,1N7QM@1224|Proteobacteria,2VVV6@28216|Betaproteobacteria,2KNBC@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Zinc-finger domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-CHCC
k59_1644451_2	909663.KI867150_gene710	1.27e-06	50.4	COG1872@1|root,COG1872@2|Bacteria,1MZ4E@1224|Proteobacteria,42VE5@68525|delta/epsilon subdivisions,2WR8T@28221|Deltaproteobacteria,2MQQD@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	DUF167	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
k59_1644454_2	709032.Sulku_1582	3.18e-32	115.0	COG2827@1|root,COG2827@2|Bacteria,1N6PA@1224|Proteobacteria,42VGM@68525|delta/epsilon subdivisions,2YQ7S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	endonuclease containing a URI domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
k59_822678_1	1279019.ARQK01000054_gene203	3.34e-89	286.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,1RPCB@1236|Gammaproteobacteria,1WWYF@135613|Chromatiales	135613|Chromatiales	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_822684_1	1304883.KI912532_gene238	2.11e-123	357.0	COG3396@1|root,COG3396@2|Bacteria,1MVQ7@1224|Proteobacteria,2VHQZ@28216|Betaproteobacteria,2KUW7@206389|Rhodocyclales	206389|Rhodocyclales	S	Phenylacetate-CoA oxygenase subunit PaaA	paaA	-	1.14.13.149	ko:K02609	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
k59_470514_1	1537917.JU82_03170	2.28e-81	254.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,42M6T@68525|delta/epsilon subdivisions,2YMJD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
k59_470546_1	1537917.JU82_02235	7.27e-103	307.0	COG0577@1|root,COG0577@2|Bacteria,1QT4V@1224|Proteobacteria,42P7K@68525|delta/epsilon subdivisions,2YNGD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	ABC transporter permease	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
k59_646882_1	1125863.JAFN01000001_gene1781	1.76e-74	240.0	COG1148@1|root,COG1148@2|Bacteria,1QUMN@1224|Proteobacteria,43BMA@68525|delta/epsilon subdivisions,2X6ZG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	hdrA	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Fer4_7,FlpD,Pyr_redox_2
k59_176797_1	1123371.ATXH01000035_gene2003	7.02e-06	55.8	COG1207@1|root,COG1344@1|root,COG1207@2|Bacteria,COG1344@2|Bacteria,2GH5Q@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	-	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_IN,Flagellin_N
k59_118254_1	536233.CLO_0161	1.53e-50	167.0	COG0110@1|root,COG0110@2|Bacteria,1TT21@1239|Firmicutes,24CCH@186801|Clostridia,36UQH@31979|Clostridiaceae	186801|Clostridia	S	Hexapeptide repeat of succinyl-transferase	wbpD	-	2.3.1.201	ko:K13018	ko00520,map00520	-	R10100	RC00004,RC00166	ko00000,ko00001,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2
k59_118254_2	1548151.LS70_03145	1.27e-05	48.1	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42M4C@68525|delta/epsilon subdivisions	1224|Proteobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
k59_822734_1	1387312.BAUS01000012_gene2078	3.71e-134	399.0	COG1132@1|root,COG1132@2|Bacteria,1N1Z8@1224|Proteobacteria	1224|Proteobacteria	V	COG1132 ABC-type multidrug transport system, ATPase and permease components	msbA	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k59_1233717_1	1249480.B649_00205	3.81e-137	395.0	COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,42UBK@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	SMART Metal-dependent phosphohydrolase, HD region	-	-	-	-	-	-	-	-	-	-	-	-	DUF3391,HD,HD_5
k59_118263_2	709032.Sulku_0525	1.07e-71	221.0	COG0745@1|root,COG0745@2|Bacteria,1R9AZ@1224|Proteobacteria,42NYS@68525|delta/epsilon subdivisions,2YNW2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	response regulator	dccR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_1527362_1	96561.Dole_2158	1.54e-33	125.0	COG0583@1|root,COG1910@1|root,COG0583@2|Bacteria,COG1910@2|Bacteria,1MWVU@1224|Proteobacteria,42PMQ@68525|delta/epsilon subdivisions,2WKB8@28221|Deltaproteobacteria,2MIF9@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Transcriptional regulator, LysR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_1527362_2	515635.Dtur_1383	3.25e-06	48.5	COG0209@1|root,COG0209@2|Bacteria	2|Bacteria	F	ribonucleoside-diphosphate reductase activity	nrdZ	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
k59_1468275_1	1249480.B649_01450	2.57e-08	62.0	COG2198@1|root,COG2198@2|Bacteria,1PCKH@1224|Proteobacteria,42W9Z@68525|delta/epsilon subdivisions,2YQ6K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1207_1	439235.Dalk_0841	6.34e-57	190.0	COG0859@1|root,COG0859@2|Bacteria,1PQIG@1224|Proteobacteria,42MUM@68525|delta/epsilon subdivisions,2WPZT@28221|Deltaproteobacteria,2MN6W@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
k59_646909_1	1502770.JQMG01000001_gene953	5.65e-24	95.5	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,2VQ1Z@28216|Betaproteobacteria,2KKVM@206350|Nitrosomonadales	206350|Nitrosomonadales	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
k59_646909_2	666681.M301_0081	1.14e-61	195.0	COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,2VIGI@28216|Betaproteobacteria,2KKE3@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
k59_998877_1	159087.Daro_1661	3.98e-12	64.7	COG0745@1|root,COG4753@1|root,COG0745@2|Bacteria,COG4753@2|Bacteria,1RETP@1224|Proteobacteria,2WGYY@28216|Betaproteobacteria	28216|Betaproteobacteria	KT	Response regulator receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
k59_998877_2	506534.Rhein_3777	3.71e-56	187.0	COG0730@1|root,COG0730@2|Bacteria,1QRFH@1224|Proteobacteria,1RRFY@1236|Gammaproteobacteria,1X0ZA@135613|Chromatiales	135613|Chromatiales	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
k59_529433_1	1132855.KB913035_gene600	1.56e-46	158.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,2VHW4@28216|Betaproteobacteria,2KM1Z@206350|Nitrosomonadales	206350|Nitrosomonadales	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
k59_649520_2	709032.Sulku_0388	3.35e-143	405.0	COG0047@1|root,COG0047@2|Bacteria,1MU4Y@1224|Proteobacteria,42MNY@68525|delta/epsilon subdivisions,2YMTM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
k59_649520_3	709032.Sulku_0389	5.83e-41	135.0	COG1828@1|root,COG1828@2|Bacteria,1N83G@1224|Proteobacteria,42V3S@68525|delta/epsilon subdivisions,2YQ9B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
k59_649520_4	709032.Sulku_0390	7.05e-66	205.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,42M8A@68525|delta/epsilon subdivisions,2YN5T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the SAICAR synthetase family	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
k59_1705437_1	717772.THIAE_10260	2.86e-71	224.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,1RNJK@1236|Gammaproteobacteria,45ZNV@72273|Thiotrichales	72273|Thiotrichales	D	PFAM CobQ CobB MinD ParA nucleotide binding domain	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,MipZ
k59_1646647_1	998088.B565_0189	1.18e-100	298.0	COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,1RN0P@1236|Gammaproteobacteria,1Y465@135624|Aeromonadales	135624|Aeromonadales	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
k59_178587_1	709032.Sulku_0182	1.65e-129	374.0	COG0492@1|root,COG0492@2|Bacteria,1NDW6@1224|Proteobacteria,42MUD@68525|delta/epsilon subdivisions,2YMV2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	pyridine nucleotide-disulfide oxidoreductase	trxB_2	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	FixS,Pyr_redox_3
k59_1705447_1	583345.Mmol_0508	3.37e-66	205.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2VQ3Z@28216|Betaproteobacteria,2KMU4@206350|Nitrosomonadales	206350|Nitrosomonadales	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
k59_1705447_2	583345.Mmol_0511	1.17e-09	57.8	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,2VHN4@28216|Betaproteobacteria,2KM9D@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
k59_61670_1	159087.Daro_1234	9.47e-09	55.1	COG0287@1|root,COG0287@2|Bacteria,1QTZA@1224|Proteobacteria,2VIS1@28216|Betaproteobacteria,2KU90@206389|Rhodocyclales	206389|Rhodocyclales	E	Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
k59_61670_2	159087.Daro_1235	2.77e-79	243.0	COG1793@1|root,COG1793@2|Bacteria,1MUW3@1224|Proteobacteria,2VI3P@28216|Betaproteobacteria,2KUKX@206389|Rhodocyclales	206389|Rhodocyclales	L	DNA ligase	dnaL	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_M,DNA_ligase_OB_2
k59_1001157_1	709032.Sulku_0132	3.39e-97	294.0	COG4773@1|root,COG4773@2|Bacteria,1QZMX@1224|Proteobacteria,42SA0@68525|delta/epsilon subdivisions,2YPCD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_825108_1	709032.Sulku_1319	1.99e-52	170.0	COG2078@1|root,COG2078@2|Bacteria,1RJP4@1224|Proteobacteria,42SBG@68525|delta/epsilon subdivisions,2YP68@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM AMMECR1 domain protein	-	-	-	ko:K09141	-	-	-	-	ko00000	-	-	-	AMMECR1
k59_4097_1	1249480.B649_05330	5.54e-52	174.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MKR@68525|delta/epsilon subdivisions,2YN1A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Aminotransferase	aspB	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_4097_2	1249480.B649_05335	8.58e-23	97.4	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42MS0@68525|delta/epsilon subdivisions,2YMTX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_1177358_1	159087.Daro_0031	1.57e-188	532.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VKD8@28216|Betaproteobacteria,2KV57@206389|Rhodocyclales	206389|Rhodocyclales	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activ_2
k59_1470235_1	159087.Daro_3796	7.74e-61	196.0	2DB9W@1|root,2Z7Z9@2|Bacteria,1MZFV@1224|Proteobacteria,2VHWP@28216|Betaproteobacteria,2KVEW@206389|Rhodocyclales	206389|Rhodocyclales	C	Methane/Phenol/Toluene Hydroxylase	-	-	-	ko:K16243	ko00361,ko00362,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00623,map01100,map01120,map01220	M00548	R03560,R03608,R10042,R10043	RC00046,RC00490	ko00000,ko00001,ko00002	-	-	-	Phenol_Hydrox
k59_1470235_2	62928.azo2444	2.35e-19	82.0	2C44J@1|root,33BV7@2|Bacteria,1NGP7@1224|Proteobacteria,2VXRT@28216|Betaproteobacteria,2KZ6E@206389|Rhodocyclales	206389|Rhodocyclales	S	Phenol hydroxylase subunit	-	-	-	ko:K16249	ko00361,ko00362,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00623,map01100,map01120,map01220	M00548	R03560,R03608,R10042,R10043	RC00046,RC00490	ko00000,ko00001,ko00002	-	-	-	Phenol_hyd_sub
k59_296199_1	36080.S2KBA8	1.33e-20	92.0	COG0531@1|root,KOG1286@2759|Eukaryota,38BM3@33154|Opisthokonta,3Q1PD@4751|Fungi,1GVEK@112252|Fungi incertae sedis	4751|Fungi	E	Mortierella verticillata NRRL 6337	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
k59_296199_2	395493.BegalDRAFT_0456	1.09e-12	70.1	COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,1S99V@1236|Gammaproteobacteria,4610E@72273|Thiotrichales	72273|Thiotrichales	K	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
k59_1118458_1	983920.Y88_1141	1.33e-07	55.1	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2TWBJ@28211|Alphaproteobacteria,2KEEC@204457|Sphingomonadales	204457|Sphingomonadales	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Hpt,MASE1,PAS_3,PAS_4,Response_reg
k59_1118458_2	159087.Daro_3308	4.72e-97	309.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VK78@28216|Betaproteobacteria,2KVI5@206389|Rhodocyclales	206389|Rhodocyclales	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k59_1001179_1	159087.Daro_1404	5.35e-142	418.0	COG2864@1|root,COG2864@2|Bacteria,1NJEJ@1224|Proteobacteria,2VKG8@28216|Betaproteobacteria,2KY24@206389|Rhodocyclales	206389|Rhodocyclales	P	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_825136_1	1218074.BAXZ01000012_gene2815	1.24e-15	82.8	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1K0RA@119060|Burkholderiaceae	28216|Betaproteobacteria	T	GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,dCache_1
k59_1823624_1	760154.Sulba_1097	1.51e-15	74.3	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,42SCV@68525|delta/epsilon subdivisions,2YPRK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar motor	motB	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
k59_1530003_1	420662.Mpe_A0976	1.8e-60	198.0	COG2379@1|root,COG2379@2|Bacteria,1MVIK@1224|Proteobacteria,2VHXK@28216|Betaproteobacteria,1KIZG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	MOFRL family	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
k59_1530003_2	1120999.JONM01000034_gene3986	3.84e-26	105.0	COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,2VH5M@28216|Betaproteobacteria,2KPRQ@206351|Neisseriales	206351|Neisseriales	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
k59_1059401_1	1168549.I6RSN8_9CAUD	4.79e-18	82.4	4QECQ@10239|Viruses,4QXZ6@35237|dsDNA viruses  no RNA stage,4QQHZ@28883|Caudovirales,4QMMZ@10699|Siphoviridae	10699|Siphoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1352974_1	1123354.AUDR01000017_gene112	2.04e-32	130.0	COG0144@1|root,COG0144@2|Bacteria,1MV2Q@1224|Proteobacteria,2VI1D@28216|Betaproteobacteria,1KRDH@119069|Hydrogenophilales	119069|Hydrogenophilales	J	16S rRNA methyltransferase RsmB/F	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N
k59_1352974_2	1236542.BALM01000024_gene2833	8.12e-11	62.4	COG0044@1|root,COG0044@2|Bacteria,1MW10@1224|Proteobacteria,1RMQC@1236|Gammaproteobacteria,2QB5A@267890|Shewanellaceae	1236|Gammaproteobacteria	F	Amidohydrolase family	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
k59_1588334_1	159087.Daro_2189	4.99e-111	334.0	COG0304@1|root,COG0304@2|Bacteria,1N4Y1@1224|Proteobacteria,2VU11@28216|Betaproteobacteria,2KXPZ@206389|Rhodocyclales	206389|Rhodocyclales	IQ	beta-ketoacyl-acyl-carrier-protein synthase II activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_61715_1	1537917.JU82_01405	1.15e-41	147.0	COG2199@1|root,COG3706@2|Bacteria,1NC00@1224|Proteobacteria,43DI1@68525|delta/epsilon subdivisions,2YTIQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	diguanylate cyclase	-	-	2.7.7.65	ko:K13590	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF
k59_1470290_1	709032.Sulku_1447	1.02e-189	535.0	COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,42KZP@68525|delta/epsilon subdivisions,2YMBP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG1055 Na H antiporter NhaD and related arsenite	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
k59_1118506_1	1537917.JU82_01510	6.28e-90	268.0	COG2227@1|root,COG2227@2|Bacteria,1QYD8@1224|Proteobacteria,43CBI@68525|delta/epsilon subdivisions,2YTHI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Ribosomal RNA adenine dimethylase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
k59_473028_1	159087.Daro_0260	1.54e-81	249.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,2VHBD@28216|Betaproteobacteria,2KVKQ@206389|Rhodocyclales	206389|Rhodocyclales	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_1823665_1	709032.Sulku_1182	2.24e-65	214.0	COG0840@1|root,COG0840@2|Bacteria,1R486@1224|Proteobacteria,42Q5Y@68525|delta/epsilon subdivisions,2YNT8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	CZB,MCPsignal
k59_942624_1	159087.Daro_0039	3.17e-06	46.2	2A4S0@1|root,30TDE@2|Bacteria,1PD67@1224|Proteobacteria,2W9FW@28216|Betaproteobacteria,2KXIG@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of unknown function (DUF1840)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1840
k59_942624_2	159087.Daro_0040	3.61e-42	157.0	COG0784@1|root,COG2198@1|root,COG3829@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG3829@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,2WGIN@28216|Betaproteobacteria,2KZWN@206389|Rhodocyclales	206389|Rhodocyclales	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_4,PAS_9,Response_reg
k59_532165_1	929558.SMGD1_2620	1.09e-56	184.0	COG3150@1|root,COG3150@2|Bacteria,1MVJF@1224|Proteobacteria,42TC2@68525|delta/epsilon subdivisions,2YPKS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Uncharacterised protein family (UPF0227)	-	-	-	ko:K07000	-	-	-	-	ko00000	-	-	-	UPF0227
k59_473039_2	709032.Sulku_0567	7.82e-52	166.0	COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,42S69@68525|delta/epsilon subdivisions,2YP0K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	cheW	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
k59_590144_1	1249480.B649_02820	1.56e-81	249.0	COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1N81M@1224|Proteobacteria,42M00@68525|delta/epsilon subdivisions,2YMF1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	chemotaxis protein	cheV	-	-	ko:K03415	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CheW,Response_reg
k59_355032_1	326298.Suden_1417	5.96e-47	166.0	COG0438@1|root,COG0438@2|Bacteria,1MY5T@1224|Proteobacteria,42NYR@68525|delta/epsilon subdivisions,2YNJT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
k59_414006_1	709032.Sulku_0566	1.47e-139	417.0	COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2YMB9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	chemotaxis protein	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k59_1118541_1	187272.Mlg_0279	3.51e-54	184.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,1RNQ8@1236|Gammaproteobacteria,1WX0A@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
k59_1470324_1	1537917.JU82_02865	1.28e-66	222.0	COG4206@1|root,COG4206@2|Bacteria,1QUGQ@1224|Proteobacteria,42PHJ@68525|delta/epsilon subdivisions,2YNKV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_296259_2	395494.Galf_0463	3.78e-77	243.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,2VH8D@28216|Betaproteobacteria,44UZ0@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Peptidase M16 inactive domain	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_1118546_1	159087.Daro_1591	9.81e-108	317.0	COG1075@1|root,COG1075@2|Bacteria,1R75P@1224|Proteobacteria,2VU4P@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PGAP1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,PGAP1
k59_1530081_1	159087.Daro_3879	2.59e-91	286.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2VJFM@28216|Betaproteobacteria,2KUF0@206389|Rhodocyclales	206389|Rhodocyclales	L	it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction	rep	-	3.6.4.12	ko:K03656	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_649699_2	367737.Abu_0443	6.24e-45	153.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,42R1W@68525|delta/epsilon subdivisions,2YNZT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Inositol monophosphatase	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
k59_1764299_1	159087.Daro_0233	1.03e-106	322.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,2VMTN@28216|Betaproteobacteria,2KVH2@206389|Rhodocyclales	206389|Rhodocyclales	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	-	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,iPGM_N
k59_473093_1	709032.Sulku_2052	7.34e-115	339.0	COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,42MI0@68525|delta/epsilon subdivisions,2YMAS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Small subunit	hydA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.12.5.1	ko:K05927	-	-	-	-	ko00000,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6,TAT_signal
k59_649729_1	317025.Tcr_0362	1.45e-88	266.0	COG0692@1|root,COG0692@2|Bacteria,1MV80@1224|Proteobacteria,1RPDH@1236|Gammaproteobacteria,460F0@72273|Thiotrichales	72273|Thiotrichales	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	-	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
k59_178714_1	159087.Daro_2516	1.07e-13	69.3	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,2VIK8@28216|Betaproteobacteria,2KVWI@206389|Rhodocyclales	206389|Rhodocyclales	BQ	COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
k59_178714_2	1304883.KI912532_gene2200	4.15e-139	402.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,2VINP@28216|Betaproteobacteria,2KUEA@206389|Rhodocyclales	206389|Rhodocyclales	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
k59_1588428_1	709032.Sulku_1182	5.55e-122	360.0	COG0840@1|root,COG0840@2|Bacteria,1R486@1224|Proteobacteria,42Q5Y@68525|delta/epsilon subdivisions,2YNT8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	CZB,MCPsignal
k59_649749_1	1537917.JU82_10060	1.17e-96	306.0	COG2911@1|root,COG2911@2|Bacteria,1PBYT@1224|Proteobacteria,42T65@68525|delta/epsilon subdivisions,2YPPD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
k59_1236225_1	522306.CAP2UW1_4536	4.52e-74	247.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2VHCZ@28216|Betaproteobacteria,1KQHT@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07239,ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1,2.A.6.1.2	-	-	ACR_tran
k59_1001345_1	709032.Sulku_1784	1.36e-162	466.0	COG2199@1|root,COG3437@1|root,COG3437@2|Bacteria,COG3706@2|Bacteria,1MUB8@1224|Proteobacteria,42PWE@68525|delta/epsilon subdivisions,2YRAF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,PAS_9,Response_reg
k59_942739_1	1249480.B649_00310	5.72e-79	251.0	COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,42RCJ@68525|delta/epsilon subdivisions,2YNX9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG4775 Outer membrane protein protective antigen OMA87	-	-	-	ko:K07278	-	-	-	-	ko00000,ko02000	1.B.33.2.4	-	-	Bac_surface_Ag,POTRA
k59_532297_1	367737.Abu_0739	1.58e-39	146.0	COG2199@1|root,COG3829@1|root,COG3706@2|Bacteria,COG3829@2|Bacteria,1R7HC@1224|Proteobacteria,42YVM@68525|delta/epsilon subdivisions,2YRBE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_9
k59_1412040_1	582744.Msip34_0573	1.21e-06	49.7	COG2980@1|root,COG2980@2|Bacteria,1N13K@1224|Proteobacteria,2VU54@28216|Betaproteobacteria,2KMX8@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane	lptE	-	-	ko:K03643	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptE
k59_1851416_2	1537917.JU82_11250	4.48e-40	134.0	2AIYH@1|root,31ARU@2|Bacteria,1Q60N@1224|Proteobacteria,42WN0@68525|delta/epsilon subdivisions,2YQ8T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function (DUF2018)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2018
k59_1851416_3	1249480.B649_07750	3.38e-58	183.0	2BT5R@1|root,32NAM@2|Bacteria,1Q3P8@1224|Proteobacteria,42XKB@68525|delta/epsilon subdivisions,2YQR6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1440279_1	1304883.KI912532_gene1539	1.31e-157	462.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,2VICG@28216|Betaproteobacteria,2KUWE@206389|Rhodocyclales	206389|Rhodocyclales	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
k59_616163_1	1249480.B649_10380	4.35e-96	290.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,42M8P@68525|delta/epsilon subdivisions,2YN6C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	peptidase U32 family	prtC	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
k59_24068_2	1410625.JHWK01000002_gene531	2.01e-10	66.6	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,27I9U@186928|unclassified Lachnospiraceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,MASE3,Response_reg
k59_1610515_1	1172190.M947_07505	3.9e-96	293.0	COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,42MDI@68525|delta/epsilon subdivisions,2YMJJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	malic enzyme	mez	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
k59_1610515_2	709032.Sulku_0917	3.52e-22	89.4	COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,42SI7@68525|delta/epsilon subdivisions,2YP7Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the UPF0178 family	-	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
k59_616171_1	1304883.KI912532_gene749	1.6e-110	331.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,2VJ8B@28216|Betaproteobacteria,2KVBV@206389|Rhodocyclales	206389|Rhodocyclales	P	Ammonium Transporter	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
k59_1786657_1	1537917.JU82_11475	1.63e-49	171.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,42MW6@68525|delta/epsilon subdivisions,2YNJR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	potassium channel protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans,Ion_trans_2,TrkA_C,TrkA_N
k59_1786657_2	709032.Sulku_0824	3.1e-28	108.0	COG1226@1|root,COG1226@2|Bacteria,1R0RZ@1224|Proteobacteria,42UWU@68525|delta/epsilon subdivisions,2YQ24@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	TrkA-N domain	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	TrkA_C,TrkA_N
k59_1851474_1	1249480.B649_03890	3.79e-145	417.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,42MQT@68525|delta/epsilon subdivisions,2YMQ6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Belongs to the SEDS family	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
k59_1086753_3	709032.Sulku_2152	1.07e-09	55.5	COG1544@1|root,COG1544@2|Bacteria,1QNAY@1224|Proteobacteria,430WG@68525|delta/epsilon subdivisions,2YS0N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Sigma 54 modulation protein / S30EA ribosomal protein	-	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
k59_726215_1	709032.Sulku_1834	2.32e-143	417.0	COG3203@1|root,COG3203@2|Bacteria,1QVBP@1224|Proteobacteria,42M72@68525|delta/epsilon subdivisions,2YNNX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	outer membrane porin, OprD family	-	-	-	-	-	-	-	-	-	-	-	-	OprD
k59_1035259_1	709032.Sulku_2026	8.85e-05	44.3	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,42KZI@68525|delta/epsilon subdivisions,2YR60@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Domain of unknown function (DUF3458_C) ARM repeats	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,Peptidase_M1
k59_1035259_2	1537917.JU82_03415	5.19e-51	173.0	COG0446@1|root,COG0446@2|Bacteria,1PWV7@1224|Proteobacteria,42QCM@68525|delta/epsilon subdivisions,2YND4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COGs COG1252 NADH dehydrogenase FAD-containing subunit	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_1672537_1	1537917.JU82_02000	3.12e-24	97.1	COG0546@1|root,COG0546@2|Bacteria,1RBMZ@1224|Proteobacteria,42RG3@68525|delta/epsilon subdivisions,2YP44@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Hydrolase	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_1789203_1	765911.Thivi_2826	0.000612	44.7	COG1058@1|root,COG1058@2|Bacteria,1MVG6@1224|Proteobacteria,1SZRM@1236|Gammaproteobacteria,1WWZE@135613|Chromatiales	135613|Chromatiales	S	Molybdopterin binding	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
k59_1789203_2	395019.Bmul_2658	4.11e-30	114.0	COG0783@1|root,COG0783@2|Bacteria,1RAC5@1224|Proteobacteria,2VHJI@28216|Betaproteobacteria,1K08S@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Belongs to the Dps family	dps	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
k59_1789203_3	641147.HMPREF9021_00376	3.41e-86	260.0	COG0678@1|root,COG0695@1|root,COG0678@2|Bacteria,COG0695@2|Bacteria,1MU0H@1224|Proteobacteria,2VKP5@28216|Betaproteobacteria,2KPQ1@206351|Neisseriales	206351|Neisseriales	O	Glutaredoxin-family domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin,Redoxin
k59_149370_2	387092.NIS_0273	1.14e-39	144.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,42M27@68525|delta/epsilon subdivisions,2YNWH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
k59_1495968_1	517417.Cpar_1078	2.29e-68	218.0	COG3258@1|root,COG3258@2|Bacteria,1FESA@1090|Chlorobi	1090|Chlorobi	C	C-type monoheme cytochrome, which is part of the SoxAX cytochrome complex involved in sulfur oxidation. The SoxAX complex catalyzes the formation of a heterodisulfide bond between the conserved cysteine residue on a sulfur carrier SoxYZ complex subunit SoxY and thiosulfate or other inorganic sulfur substrates. This leads to the liberation of two electrons, which may be transferred from the SoxAX complex to another cytochrome c and which then may be used for reductive CO(2) fixation	-	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005623,GO:0006091,GO:0006464,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0016667,GO:0016669,GO:0018192,GO:0018193,GO:0018198,GO:0018307,GO:0019417,GO:0019538,GO:0020037,GO:0022900,GO:0032991,GO:0036211,GO:0042597,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046872,GO:0046906,GO:0046914,GO:0046982,GO:0046983,GO:0048037,GO:0055114,GO:0070069,GO:0071704,GO:0097159,GO:0098822,GO:1901363,GO:1901564	-	ko:K17222	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	-
k59_1495968_2	1279038.KB907343_gene2480	1.29e-29	110.0	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,2TU1S@28211|Alphaproteobacteria,2JRQP@204441|Rhodospirillales	204441|Rhodospirillales	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
k59_1443802_1	1249480.B649_09120	1.6e-85	265.0	COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,42N4Y@68525|delta/epsilon subdivisions,2YNCE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase,Methyltransf_11,Methyltransf_31
k59_83249_1	1380355.JNIJ01000010_gene1443	1.07e-168	480.0	COG4663@1|root,COG4663@2|Bacteria,1MUXI@1224|Proteobacteria,2TQVW@28211|Alphaproteobacteria,3JWB9@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP,TAT_signal
k59_149391_1	1249480.B649_05210	1.18e-120	346.0	COG0745@1|root,COG0745@2|Bacteria,1Q5DC@1224|Proteobacteria,42R42@68525|delta/epsilon subdivisions,2YNXG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_681093_1	709032.Sulku_0129	3.12e-86	282.0	COG0439@1|root,COG1984@1|root,COG2049@1|root,COG0439@2|Bacteria,COG1984@2|Bacteria,COG2049@2|Bacteria,1MU4H@1224|Proteobacteria,42P49@68525|delta/epsilon subdivisions,2YNRZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EI	Allophanate hydrolase subunit 1	-	-	6.3.4.6	ko:K01941	ko00220,ko00791,ko01100,map00220,map00791,map01100	-	R00774	RC00378	ko00000,ko00001,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,CT_A_B,CT_C_D
k59_1672592_1	1249480.B649_05740	3.37e-16	72.8	COG0818@1|root,COG0818@2|Bacteria,1Q5TS@1224|Proteobacteria,42SZA@68525|delta/epsilon subdivisions,2YSYV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Recycling of diacylglycerol produced during the turnover of membrane phospholipid	-	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
k59_1672592_2	709032.Sulku_1357	2.67e-142	421.0	COG0204@1|root,COG0477@1|root,COG0204@2|Bacteria,COG2814@2|Bacteria,1MWDY@1224|Proteobacteria,43BJD@68525|delta/epsilon subdivisions,2YNEB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	2-acylglycerophosphoethanolamine acyltransferase	aas	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
k59_1443842_1	1355368.JART01000019_gene1030	1.3e-09	56.2	COG3668@1|root,COG3668@2|Bacteria,1PZJG@1224|Proteobacteria,42Y3N@68525|delta/epsilon subdivisions,2YQTP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
k59_1443842_3	1249480.B649_00505	6.18e-15	72.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,42M44@68525|delta/epsilon subdivisions,2YMH6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth,NMO
k59_149423_1	675816.VIA_000065	7.66e-86	265.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,1RP95@1236|Gammaproteobacteria,1XT0A@135623|Vibrionales	135623|Vibrionales	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
k59_1613236_1	709032.Sulku_1848	4.54e-42	148.0	COG0754@1|root,COG0754@2|Bacteria,1MW6V@1224|Proteobacteria,42N3V@68525|delta/epsilon subdivisions,2YMBJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Glutathionylspermidine synthase	gss	-	-	-	-	-	-	-	-	-	-	-	GSP_synth
k59_1613236_2	1537917.JU82_09130	2.69e-45	152.0	28WAS@1|root,2ZIB8@2|Bacteria,1NBB7@1224|Proteobacteria,42P2G@68525|delta/epsilon subdivisions,2YNQ5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1316860_1	1387312.BAUS01000012_gene2081	4.24e-34	134.0	COG4625@1|root,COG4625@2|Bacteria,1R9VZ@1224|Proteobacteria,2WEH9@28216|Betaproteobacteria	28216|Betaproteobacteria	U	Autotransporter beta-domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,ESPR
k59_1316860_2	579405.Dd703_1884	8.22e-08	55.5	COG1073@1|root,COG1073@2|Bacteria,1R8S6@1224|Proteobacteria,1S4WS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	FSH1,Lipase_3
k59_26285_1	1537917.JU82_10900	1.12e-103	318.0	COG0493@1|root,COG1894@1|root,COG0493@2|Bacteria,COG1894@2|Bacteria,1MU2H@1224|Proteobacteria,42M6X@68525|delta/epsilon subdivisions,2YM9W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COGs COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase	-	-	1.17.1.10	ko:K15022	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00377	R00134	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_20,NADH_4Fe-4S,Pyr_redox_2
k59_263384_1	387093.SUN_0164	5.04e-11	60.1	COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,42RJW@68525|delta/epsilon subdivisions,2YP85@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
k59_263384_2	387093.SUN_0163	1.63e-36	124.0	2AJEY@1|root,31A0Z@2|Bacteria,1Q4KX@1224|Proteobacteria,4325F@68525|delta/epsilon subdivisions,2YSRD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_851110_1	880070.Cycma_0162	5.72e-115	340.0	COG0673@1|root,COG0673@2|Bacteria,4NH96@976|Bacteroidetes,47M0H@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
k59_1149187_1	1249480.B649_08995	2.31e-130	376.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42Q5V@68525|delta/epsilon subdivisions,2YND0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
k59_1854924_1	1128427.KB904821_gene510	1.04e-18	90.9	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1G40D@1117|Cyanobacteria,1H9NF@1150|Oscillatoriales	1117|Cyanobacteria	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
k59_1035429_1	1249480.B649_11260	7.8e-74	231.0	COG0249@1|root,COG0249@2|Bacteria,1Q1X0@1224|Proteobacteria,42UKG@68525|delta/epsilon subdivisions,2YQ3M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KLT	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1035429_2	1165841.SULAR_02953	1e-28	115.0	COG1283@1|root,COG1283@2|Bacteria,1MUDE@1224|Proteobacteria,42PW9@68525|delta/epsilon subdivisions,2YN4S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Na Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans
k59_1035430_2	90814.KL370891_gene1420	1.54e-109	331.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,1RMYA@1236|Gammaproteobacteria,4604I@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,Pribosyltran
k59_378200_1	159087.Daro_1827	1.24e-12	68.2	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,2KU97@206389|Rhodocyclales	206389|Rhodocyclales	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_205601_1	1121035.AUCH01000006_gene729	1.11e-44	150.0	COG0765@1|root,COG0765@2|Bacteria,1MUVX@1224|Proteobacteria,2VJ8A@28216|Betaproteobacteria,2KVZV@206389|Rhodocyclales	206389|Rhodocyclales	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10003	ko02010,ko02020,map02010,map02020	M00230	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.19,3.A.1.3.4	-	-	BPD_transp_1
k59_205601_2	1124983.PFLCHA0_c21450	1.18e-49	167.0	COG0252@1|root,COG0252@2|Bacteria,1MWIR@1224|Proteobacteria,1RNPN@1236|Gammaproteobacteria,1YNZY@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	EJ	Belongs to the asparaginase 1 family	ansB	GO:0003674,GO:0003824,GO:0004067,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006530,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009066,GO:0009068,GO:0009987,GO:0016043,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0022607,GO:0030288,GO:0030313,GO:0031975,GO:0032787,GO:0034641,GO:0042597,GO:0042802,GO:0043436,GO:0043603,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:0072329,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	3.5.1.1,3.5.1.38	ko:K01424,ko:K05597	ko00220,ko00250,ko00460,ko00471,ko01100,ko01110,ko02020,map00220,map00250,map00460,map00471,map01100,map01110,map02020	-	R00256,R00485,R01579	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
k59_502441_1	983917.RGE_00720	1.11e-35	131.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,2VHI1@28216|Betaproteobacteria,1KJQ6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
k59_26318_1	1537917.JU82_10595	2.37e-28	117.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,42Q9B@68525|delta/epsilon subdivisions,2YNKN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.2.3	ko:K17229	ko00920,ko01120,map00920,map01120	-	R09499	-	ko00000,ko00001,ko01000	-	-	-	FCSD-flav_bind,Pyr_redox_2,TAT_signal
k59_726312_1	1537917.JU82_10020	7.18e-162	459.0	COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,42P1T@68525|delta/epsilon subdivisions,2YMMQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the dGTPase family. Type 2 subfamily	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
k59_1854947_1	317025.Tcr_1002	9.49e-44	153.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,1RNPT@1236|Gammaproteobacteria,46028@72273|Thiotrichales	72273|Thiotrichales	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceF	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
k59_1854947_2	1168067.JAGP01000001_gene1219	2.06e-77	251.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,45ZSE@72273|Thiotrichales	72273|Thiotrichales	C	dihydrolipoamide dehydrogenase	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
k59_1496068_1	1304883.KI912532_gene1619	1.28e-20	89.7	COG0827@1|root,COG0827@2|Bacteria,1QP3Z@1224|Proteobacteria,2VI9V@28216|Betaproteobacteria,2KVWP@206389|Rhodocyclales	206389|Rhodocyclales	L	Eco57I restriction-modification methylase	-	-	2.1.1.72	ko:K07317	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Eco57I
k59_1496068_2	159087.Daro_3450	4.35e-71	220.0	COG0284@1|root,COG0284@2|Bacteria,1MWH5@1224|Proteobacteria,2VHAB@28216|Betaproteobacteria,2KUGT@206389|Rhodocyclales	206389|Rhodocyclales	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
k59_1561428_1	1070319.CAGGBEG34_230023	4.49e-83	255.0	COG1834@1|root,COG1834@2|Bacteria,1R545@1224|Proteobacteria,2VTWQ@28216|Betaproteobacteria,1KB7W@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf
k59_149527_3	1249480.B649_05650	7.79e-08	52.4	COG4786@1|root,COG4786@2|Bacteria,1MVMA@1224|Proteobacteria,42N3R@68525|delta/epsilon subdivisions,2YMWT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Belongs to the flagella basal body rod proteins family	flgG	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k59_1086926_1	1165841.SULAR_06288	4.36e-71	228.0	COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,42KZP@68525|delta/epsilon subdivisions,2YMBP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG1055 Na H antiporter NhaD and related arsenite	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
k59_619617_2	1249480.B649_00135	1.99e-69	212.0	2AIZZ@1|root,319I0@2|Bacteria,1Q2U7@1224|Proteobacteria,42W9A@68525|delta/epsilon subdivisions,2YQB5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1496077_1	1132855.KB913035_gene2507	3.46e-234	647.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,2VH5D@28216|Betaproteobacteria,2KKR0@206350|Nitrosomonadales	206350|Nitrosomonadales	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
k59_1443976_2	709032.Sulku_1661	2.68e-65	201.0	COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,42SWG@68525|delta/epsilon subdivisions,2YPN8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Chemotaxis protein CheW	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
k59_317339_1	709032.Sulku_2226	1.8e-51	166.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,42SR7@68525|delta/epsilon subdivisions,2YP8T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	nucleotide-binding protein implicated in inhibition of septum formation	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
k59_317339_2	709032.Sulku_2227	5.41e-67	207.0	COG5615@1|root,COG5615@2|Bacteria,1Q1AZ@1224|Proteobacteria,42T6C@68525|delta/epsilon subdivisions,2YPN6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_378254_1	1121456.ATVA01000011_gene1796	1.81e-18	89.4	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,42MIH@68525|delta/epsilon subdivisions,2WK3V@28221|Deltaproteobacteria,2M97X@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Metal-dependent hydrolase HDOD	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
k59_1086970_2	1537917.JU82_08720	3.99e-112	325.0	2AIDI@1|root,31TAR@2|Bacteria,1QR0P@1224|Proteobacteria,42TWA@68525|delta/epsilon subdivisions,2YSYQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PilO
k59_1035545_1	1249480.B649_10630	2.5e-36	125.0	COG1815@1|root,COG1815@2|Bacteria,1PSBA@1224|Proteobacteria,42VSQ@68525|delta/epsilon subdivisions,2YPMD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body	-	-	-	ko:K02387	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod
k59_1613407_1	1244869.H261_18452	8.06e-80	250.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2TVTA@28211|Alphaproteobacteria,2JR9T@204441|Rhodospirillales	204441|Rhodospirillales	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
k59_1855054_1	709032.Sulku_0842	7.45e-37	136.0	COG1538@1|root,COG1538@2|Bacteria,1QNYC@1224|Proteobacteria,42TDW@68525|delta/epsilon subdivisions,2YPR5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_1855054_2	1249480.B649_07900	2.44e-32	125.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42NVA@68525|delta/epsilon subdivisions,2YMYW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
k59_378281_1	861299.J421_1629	4.47e-16	82.8	COG2866@1|root,COG2866@2|Bacteria,1ZSMP@142182|Gemmatimonadetes	2|Bacteria	E	Zinc carboxypeptidase	-	-	-	ko:K14054	-	-	-	-	ko00000	-	-	-	AstE_AspA,Peptidase_M14
k59_564517_1	709032.Sulku_1098	2.76e-42	142.0	COG2214@1|root,COG2214@2|Bacteria,1RCRR@1224|Proteobacteria	1224|Proteobacteria	O	PFAM heat shock protein DnaJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
k59_564517_2	709032.Sulku_1097	3.27e-21	85.1	2C948@1|root,32SAI@2|Bacteria,1MZC2@1224|Proteobacteria,42U40@68525|delta/epsilon subdivisions,2YPYK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Putative mono-oxygenase ydhR	-	-	-	-	-	-	-	-	-	-	-	-	ydhR
k59_263515_1	979533.F1D0U7_9CAUD	2.91e-81	253.0	4QFIC@10239|Viruses,4QXG2@35237|dsDNA viruses  no RNA stage,4QTVA@28883|Caudovirales,4QNVH@10744|Podoviridae	10744|Podoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1087015_1	748280.NH8B_1878	4.31e-84	266.0	COG3540@1|root,COG3540@2|Bacteria,1MXG8@1224|Proteobacteria,2VP3C@28216|Betaproteobacteria,2KTHU@206351|Neisseriales	206351|Neisseriales	P	PhoD-like phosphatase	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD
k59_1496151_2	387093.SUN_0307	9.28e-38	130.0	29EHP@1|root,301FM@2|Bacteria,1Q6TI@1224|Proteobacteria,433SJ@68525|delta/epsilon subdivisions,2YSVK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1496153_1	709032.Sulku_2063	1.04e-89	282.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2YNUN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit	-	-	-	ko:K14086	-	-	-	-	ko00000	-	-	-	Proton_antipo_M,Proton_antipo_N
k59_1035636_1	1485544.JQKP01000001_gene1324	1.87e-73	231.0	2C60N@1|root,33S2Z@2|Bacteria,1NSI8@1224|Proteobacteria,2W0QW@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1561585_1	864563.HMPREF9166_2253	3.08e-22	104.0	COG1541@1|root,COG1541@2|Bacteria,1V5FH@1239|Firmicutes	1239|Firmicutes	H	coenzyme F390 synthetase	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding
k59_1496164_1	204536.SULAZ_0730	1.51e-62	215.0	COG3696@1|root,COG3696@2|Bacteria	2|Bacteria	P	silver ion transport	czcA	-	-	ko:K07787,ko:K15726	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.2,2.A.6.1.4	-	-	ACR_tran
k59_726406_1	1122138.AQUZ01000012_gene5981	3.14e-33	128.0	COG1089@1|root,COG1089@2|Bacteria,2GNMA@201174|Actinobacteria,4DPK0@85009|Propionibacteriales	201174|Actinobacteria	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
k59_1855124_1	1249480.B649_02370	4.09e-86	266.0	COG1419@1|root,COG1419@2|Bacteria,1MUQW@1224|Proteobacteria,42NBF@68525|delta/epsilon subdivisions,2YN28@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar biosynthesis	flhF	-	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	SRP54
k59_794039_1	1249480.B649_06820	5.92e-81	250.0	COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,42QJ2@68525|delta/epsilon subdivisions,2YNBV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COGs COG3864 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
k59_794039_2	709032.Sulku_1541	3.72e-141	404.0	COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,42QA8@68525|delta/epsilon subdivisions,2YNH6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_3
k59_619759_1	1249480.B649_11680	8.38e-90	278.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,42MK9@68525|delta/epsilon subdivisions,2YNM1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	ATPase related to phosphate starvation-inducible protein PhoH	phoH	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
k59_1731394_1	1249480.B649_03265	4.59e-71	231.0	COG2199@1|root,COG2199@2|Bacteria,1QTZT@1224|Proteobacteria,43E8E@68525|delta/epsilon subdivisions,2YN2B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_1410631_2	317025.Tcr_0611	2.22e-74	237.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,1RMWE@1236|Gammaproteobacteria,4609G@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
k59_588989_1	857087.Metme_4569	5.37e-39	132.0	2F8FM@1|root,340UB@2|Bacteria,1NXU1@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1351917_1	159087.Daro_3353	7.85e-55	177.0	COG3672@1|root,COG3672@2|Bacteria,1RDQS@1224|Proteobacteria,2VR6A@28216|Betaproteobacteria,2KWI6@206389|Rhodocyclales	206389|Rhodocyclales	S	Bacterial transglutaminase-like cysteine proteinase BTLCP	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C93
k59_1351917_2	159087.Daro_3354	1.76e-34	130.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1MUQV@1224|Proteobacteria,2VJ24@28216|Betaproteobacteria,2KZNZ@206389|Rhodocyclales	206389|Rhodocyclales	T	LapD/MoxY periplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,LapD_MoxY_N
k59_353901_1	1537917.JU82_05240	1.11e-279	771.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2YMB5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	abc transporter atp-binding protein	yheS	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
k59_473857_1	317025.Tcr_0455	1.2e-117	369.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,45ZPF@72273|Thiotrichales	72273|Thiotrichales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1589097_1	709032.Sulku_0959	5.98e-114	341.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42Z0P@68525|delta/epsilon subdivisions,2YR4F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG0513 Superfamily II DNA and RNA	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k59_533128_1	358220.C380_20075	8.56e-79	246.0	COG0183@1|root,COG0183@2|Bacteria,1MU8C@1224|Proteobacteria,2VNHE@28216|Betaproteobacteria,4AH7I@80864|Comamonadaceae	28216|Betaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k59_473861_1	416591.Tlet_0943	1.78e-11	69.3	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	DUF5122,SBBP
k59_707700_1	204536.SULAZ_0730	1.17e-76	254.0	COG3696@1|root,COG3696@2|Bacteria	2|Bacteria	P	silver ion transport	czcA	-	-	ko:K07787,ko:K15726	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.2,2.A.6.1.4	-	-	ACR_tran
k59_533133_1	1537917.JU82_05935	3.16e-45	148.0	COG0360@1|root,COG0360@2|Bacteria,1RH82@1224|Proteobacteria,42TJR@68525|delta/epsilon subdivisions,2YPZ0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
k59_1764992_1	1537917.JU82_11155	3e-58	185.0	2BTHZ@1|root,32NQF@2|Bacteria,1Q3WY@1224|Proteobacteria,42XXM@68525|delta/epsilon subdivisions,2YQUG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1764992_2	1537917.JU82_11150	4.48e-69	223.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,42M1C@68525|delta/epsilon subdivisions,2YMF3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
k59_826088_1	598659.NAMH_1014	1.42e-23	94.0	COG3162@1|root,COG3162@2|Bacteria,1MZF3@1224|Proteobacteria,42THN@68525|delta/epsilon subdivisions,2YPTV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF485
k59_826088_2	159087.Daro_0228	1.1e-29	115.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,1MVU6@1224|Proteobacteria,2VH37@28216|Betaproteobacteria,2KUE9@206389|Rhodocyclales	206389|Rhodocyclales	C	Electron transfer flavoprotein-ubiquinone oxidoreductase	-	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO,NAD_binding_8
k59_1647568_1	709032.Sulku_1313	3.25e-86	265.0	COG0778@1|root,COG0778@2|Bacteria,1Q0G9@1224|Proteobacteria,42MWR@68525|delta/epsilon subdivisions,2YNCN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	TIGRFAM SagB-type dehydrogenase domain	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_590912_1	709032.Sulku_1667	5.9e-14	80.1	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42NFY@68525|delta/epsilon subdivisions,2YRBR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS,PAS_3
k59_533190_1	1132855.KB913035_gene892	1.47e-107	319.0	COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,2VNGX@28216|Betaproteobacteria,2KMF3@206350|Nitrosomonadales	206350|Nitrosomonadales	D	Part of the ABC transporter FtsEX involved in cellular division	-	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	-
k59_590932_2	425104.Ssed_1154	2.74e-07	51.2	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1SAEA@1236|Gammaproteobacteria,2QCK3@267890|Shewanellaceae	1236|Gammaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_1353820_2	1537917.JU82_08285	3.75e-73	229.0	COG2956@1|root,COG2956@2|Bacteria,1QUIS@1224|Proteobacteria,42M7G@68525|delta/epsilon subdivisions,2YMKN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_7,TPR_8
k59_1589144_2	1161935.H9D1H5_9CAUD	1.05e-169	498.0	4QCM5@10239|Viruses,4QVZY@35237|dsDNA viruses  no RNA stage,4QQFH@28883|Caudovirales,4QNDH@10744|Podoviridae	10744|Podoviridae	S	Bacteriophage head to tail connecting protein	-	GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019028,GO:0019058,GO:0019068,GO:0019072,GO:0019073,GO:0032991,GO:0044403,GO:0044419,GO:0044423,GO:0046798,GO:0051704	-	-	-	-	-	-	-	-	-	-	-
k59_590938_1	640081.Dsui_0635	4.69e-129	372.0	COG0834@1|root,COG0834@2|Bacteria,1MV5D@1224|Proteobacteria,2VHFS@28216|Betaproteobacteria,2KUID@206389|Rhodocyclales	206389|Rhodocyclales	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	ko:K10001	ko02010,ko02020,map02010,map02020	M00230	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.19,3.A.1.3.4	-	-	SBP_bac_3
k59_590938_2	640081.Dsui_0636	1.78e-61	196.0	COG0765@1|root,COG0765@2|Bacteria,1MUVX@1224|Proteobacteria,2VJ8A@28216|Betaproteobacteria,2KVZV@206389|Rhodocyclales	206389|Rhodocyclales	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10003	ko02010,ko02020,map02010,map02020	M00230	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.19,3.A.1.3.4	-	-	BPD_transp_1
k59_179332_1	1123514.KB905899_gene723	4.11e-39	140.0	COG0446@1|root,COG0446@2|Bacteria,1QA17@1224|Proteobacteria,1RSA6@1236|Gammaproteobacteria,45ZTC@72273|Thiotrichales	72273|Thiotrichales	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_179332_2	579405.Dd703_2307	6.13e-08	55.8	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RQFI@1236|Gammaproteobacteria,2JDTT@204037|Dickeya	1236|Gammaproteobacteria	NT	SMART chemotaxis sensory transducer	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,TarH
k59_5392_1	709032.Sulku_1314	7.54e-63	203.0	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,42MSF@68525|delta/epsilon subdivisions,2YNA7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	alanine dehydrogenase	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
k59_121434_1	1249480.B649_08100	1.55e-195	549.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,42PGM@68525|delta/epsilon subdivisions,2YTQ3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
k59_121434_2	709032.Sulku_0799	9.44e-35	131.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YM7R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Efflux pump membrane transporter	-	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_1295331_1	159087.Daro_4025	8.32e-60	191.0	COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,2VKXN@28216|Betaproteobacteria,2KUI2@206389|Rhodocyclales	206389|Rhodocyclales	S	membrane transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	TauE
k59_1295331_2	159087.Daro_4024	3.47e-48	160.0	COG1802@1|root,COG1802@2|Bacteria,1R90Y@1224|Proteobacteria,2VKEN@28216|Betaproteobacteria,2KZVA@206389|Rhodocyclales	206389|Rhodocyclales	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
k59_533263_1	1249480.B649_05085	8.29e-126	380.0	COG1344@1|root,COG1344@2|Bacteria,1N1QF@1224|Proteobacteria,42PDD@68525|delta/epsilon subdivisions,2YMYD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	flgL	-	-	ko:K02397	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
k59_1706379_1	709032.Sulku_1839	5.85e-84	263.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,42MEM@68525|delta/epsilon subdivisions,2YMWQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
k59_533273_1	1304883.KI912532_gene573	5.55e-53	185.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,2VHUY@28216|Betaproteobacteria,2KUPX@206389|Rhodocyclales	206389|Rhodocyclales	E	glutamate synthase	gls1	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_533273_2	1502770.JQMG01000001_gene794	1.91e-31	120.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,2VIHR@28216|Betaproteobacteria,2KKRV@206350|Nitrosomonadales	206350|Nitrosomonadales	E	TIGRFAM glutamate synthase, NADH NADPH, small subunit	-	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
k59_1295344_2	582744.Msip34_1203	2.53e-84	262.0	COG0160@1|root,COG0160@2|Bacteria,1QTZ3@1224|Proteobacteria,2VHZE@28216|Betaproteobacteria,2KNKT@206350|Nitrosomonadales	206350|Nitrosomonadales	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
k59_238771_1	159087.Daro_0579	2.76e-42	141.0	COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,2VSH8@28216|Betaproteobacteria,2KWQ1@206389|Rhodocyclales	206389|Rhodocyclales	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	dfrA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
k59_238771_2	1304883.KI912532_gene1385	4.55e-97	299.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,2VHR9@28216|Betaproteobacteria,2KU7B@206389|Rhodocyclales	206389|Rhodocyclales	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
k59_590983_1	666681.M301_2745	1.06e-34	126.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,2VHSA@28216|Betaproteobacteria,2KM3M@206350|Nitrosomonadales	206350|Nitrosomonadales	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
k59_590983_3	469595.CSAG_02241	2.46e-21	91.3	COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,1RMM8@1236|Gammaproteobacteria,3WVB3@544|Citrobacter	1236|Gammaproteobacteria	H	Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX	hemF	GO:0003674,GO:0003824,GO:0004109,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016634,GO:0018130,GO:0019438,GO:0030145,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0046983,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b2436,iBWG_1329.BWG_2198,iECDH10B_1368.ECDH10B_2601,iECDH1ME8569_1439.ECDH1ME8569_2370,iETEC_1333.ETEC_2549,iEcDH1_1363.EcDH1_1225,iEcHS_1320.EcHS_A2573,iEcolC_1368.EcolC_1243,iJO1366.b2436,iJR904.b2436,iY75_1357.Y75_RS12760	Coprogen_oxidas
k59_650795_1	1249480.B649_01175	1.06e-99	313.0	COG1034@1|root,COG1034@2|Bacteria,1RCFT@1224|Proteobacteria,42NK4@68525|delta/epsilon subdivisions,2YNI6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G)	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4,Fer4_7,NADH-G_4Fe-4S_3
k59_1002242_1	1537917.JU82_02990	3.42e-80	243.0	COG0704@1|root,COG0704@2|Bacteria,1Q5TJ@1224|Proteobacteria,42STN@68525|delta/epsilon subdivisions,2YPRM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	PhoU family	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
k59_1178290_1	159087.Daro_3538	5.58e-87	261.0	COG1451@1|root,COG1451@2|Bacteria,1MXZU@1224|Proteobacteria,2VNC5@28216|Betaproteobacteria,2KWES@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
k59_1589221_1	159087.Daro_1302	9.25e-99	303.0	COG0582@1|root,COG0582@2|Bacteria,1PXUJ@1224|Proteobacteria,2VR8Z@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
k59_1412959_1	709032.Sulku_2307	4.71e-192	541.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,42MZZ@68525|delta/epsilon subdivisions,2YMM3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	molybdopterin biosynthesis	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
k59_1765121_1	1397528.Q671_17270	8.3e-71	228.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,1RN5S@1236|Gammaproteobacteria,1XI7M@135619|Oceanospirillales	135619|Oceanospirillales	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
k59_121475_1	1537917.JU82_00145	1.54e-44	157.0	COG0840@1|root,COG0840@2|Bacteria,1PNV4@1224|Proteobacteria,42YFX@68525|delta/epsilon subdivisions,2YRME@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
k59_121475_2	1537917.JU82_00150	9.84e-25	95.9	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42UQ6@68525|delta/epsilon subdivisions,2YQ4Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	PFAM PAS fold-3 domain protein	-	-	-	ko:K03776	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	PAS_3
k59_591007_1	1385517.N800_14075	5e-11	64.7	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,1X4J8@135614|Xanthomonadales	135614|Xanthomonadales	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_296976_1	159087.Daro_3805	1.18e-21	90.9	COG0346@1|root,COG0346@2|Bacteria,1MUWY@1224|Proteobacteria,2VKV3@28216|Betaproteobacteria,2KVH4@206389|Rhodocyclales	206389|Rhodocyclales	E	Catechol 2,3-dioxygenase, LapB	-	-	1.13.11.2	ko:K00446	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
k59_296976_2	322710.Avin_30750	4.81e-88	266.0	2DB9W@1|root,2Z7Z9@2|Bacteria,1MZFV@1224|Proteobacteria,1RRZT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Methane/Phenol/Toluene Hydroxylase	mphL	GO:0003674,GO:0003824,GO:0004497,GO:0006725,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016491,GO:0016705,GO:0016709,GO:0018662,GO:0018958,GO:0018959,GO:0019336,GO:0019439,GO:0044237,GO:0044248,GO:0046191,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616	-	ko:K16243	ko00361,ko00362,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00623,map01100,map01120,map01220	M00548	R03560,R03608,R10042,R10043	RC00046,RC00490	ko00000,ko00001,ko00002	-	-	-	Phenol_Hydrox
k59_414905_1	983917.RGE_23260	7.59e-10	67.0	COG0642@1|root,COG0784@1|root,COG2197@1|root,COG2198@1|root,COG2202@1|root,COG0784@2|Bacteria,COG2197@2|Bacteria,COG2198@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria,1KJCZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
k59_884585_1	1454004.AW11_01516	7.82e-101	315.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VH8J@28216|Betaproteobacteria,1KQA1@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	P	YHS domain	silP	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
k59_1765133_1	709032.Sulku_1127	7.64e-116	343.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42MGY@68525|delta/epsilon subdivisions,2YN2P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Glutamate synthase	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2,Pyr_redox_3
k59_943683_2	1304883.KI912532_gene69	8.13e-61	194.0	COG3149@1|root,COG3149@2|Bacteria,1R36I@1224|Proteobacteria,2WIFT@28216|Betaproteobacteria,2KZQZ@206389|Rhodocyclales	206389|Rhodocyclales	U	Type II secretion system (T2SS), protein M	-	-	-	ko:K12280	-	-	-	-	ko00000,ko02044	-	-	-	T2SSM
k59_1353921_1	583345.Mmol_1496	6.7e-34	128.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,2VIWS@28216|Betaproteobacteria,2KNIN@206350|Nitrosomonadales	206350|Nitrosomonadales	NU	Type II/IV secretion system protein	-	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_414916_1	420324.KI911970_gene1460	1.54e-26	115.0	COG5301@1|root,COG5301@2|Bacteria,1N4CW@1224|Proteobacteria,2TYJK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Phage T7 tail fibre protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_T7_tail
k59_1647721_1	1249480.B649_01685	1.72e-139	400.0	COG1639@1|root,COG1639@2|Bacteria,1Q1C5@1224|Proteobacteria,42T98@68525|delta/epsilon subdivisions,2YPNT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_1824898_1	159087.Daro_0312	2.58e-139	430.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,2VHF3@28216|Betaproteobacteria,2KV0Q@206389|Rhodocyclales	206389|Rhodocyclales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_1824898_2	159087.Daro_0311	1.09e-54	174.0	COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,2VSG7@28216|Betaproteobacteria,2KWTF@206389|Rhodocyclales	206389|Rhodocyclales	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
k59_1824900_1	159087.Daro_1934	1.51e-79	266.0	COG0784@1|root,COG3290@1|root,COG5002@1|root,COG0784@2|Bacteria,COG3290@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,2WGIN@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K20974	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_4,PAS_7,PAS_9,Response_reg,dCache_1
k59_1647727_1	1249480.B649_10410	2.62e-139	416.0	COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,42M8J@68525|delta/epsilon subdivisions,2YNGB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member	recD	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2,Viral_helicase1
k59_62503_1	1121035.AUCH01000001_gene1956	1.08e-28	119.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2WGK9@28216|Betaproteobacteria,2KY2U@206389|Rhodocyclales	206389|Rhodocyclales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
k59_5531_1	1537917.JU82_07940	1.31e-93	279.0	COG3258@1|root,COG3258@2|Bacteria,1MXB0@1224|Proteobacteria,42MIC@68525|delta/epsilon subdivisions,2YN8V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Thiosulfate-oxidizing multienzyme system protein SoxA	-	-	-	ko:K17222	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	-
k59_297009_1	395494.Galf_1596	1.37e-104	305.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,2VH4T@28216|Betaproteobacteria,44VHQ@713636|Nitrosomonadales	28216|Betaproteobacteria	J	TIGRFAM Sua5 YciO YrdC YwlC family protein	yciO	-	-	-	-	-	-	-	-	-	-	-	Sua5_yciO_yrdC
k59_591048_1	1249480.B649_06300	1.93e-07	52.4	2AJ5W@1|root,319QH@2|Bacteria,1Q3KI@1224|Proteobacteria,42XGD@68525|delta/epsilon subdivisions,2YQUZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_591048_2	1537917.JU82_11380	1.04e-63	209.0	COG1538@1|root,COG1538@2|Bacteria,1QNYC@1224|Proteobacteria,42TDW@68525|delta/epsilon subdivisions,2YPR5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_943716_1	159087.Daro_0657	1.46e-123	360.0	COG2198@1|root,COG2206@1|root,COG2198@2|Bacteria,COG2206@2|Bacteria,1RA8P@1224|Proteobacteria,2VNF3@28216|Betaproteobacteria,2KVB7@206389|Rhodocyclales	206389|Rhodocyclales	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_5,Hpt
k59_355980_1	1537917.JU82_11090	5.23e-48	155.0	COG0167@1|root,COG0167@2|Bacteria	2|Bacteria	F	dihydroorotate dehydrogenase activity	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
k59_1706463_1	1249480.B649_08165	7.65e-96	304.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,42MKB@68525|delta/epsilon subdivisions,2YMIZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
k59_1647748_1	159087.Daro_2832	1.71e-33	129.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,2VHKP@28216|Betaproteobacteria,2KVQM@206389|Rhodocyclales	206389|Rhodocyclales	S	DNA internalization-related competence protein ComEC Rec2	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
k59_1647748_2	1123367.C666_17470	1.41e-19	83.2	COG3216@1|root,COG3216@2|Bacteria,1RGV6@1224|Proteobacteria,2VSHR@28216|Betaproteobacteria,2KW1R@206389|Rhodocyclales	206389|Rhodocyclales	S	protein conserved in bacteria	-	-	-	ko:K09928	-	-	-	-	ko00000	-	-	-	DUF2062
k59_414947_1	1537917.JU82_09320	4.36e-117	370.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2YMRQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_1765170_1	998088.B565_2390	1e-65	220.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,1RMIQ@1236|Gammaproteobacteria,1Y3MP@135624|Aeromonadales	135624|Aeromonadales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD-TM1,SecD_SecF,Sec_GG
k59_1824943_1	159087.Daro_2349	6.29e-22	88.6	COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,2VQA2@28216|Betaproteobacteria,2KW5U@206389|Rhodocyclales	206389|Rhodocyclales	O	FKBP-type peptidyl-prolyl cis-trans	slyD	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
k59_1824943_2	159087.Daro_2362	9.71e-94	275.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,2VRCR@28216|Betaproteobacteria,2KW89@206389|Rhodocyclales	206389|Rhodocyclales	O	Bacterial protein of unknown function (DUF899)	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
k59_1824943_3	159087.Daro_2363	3.11e-31	110.0	COG2919@1|root,COG2919@2|Bacteria,1N7AA@1224|Proteobacteria,2VVQJ@28216|Betaproteobacteria,2KX4Q@206389|Rhodocyclales	206389|Rhodocyclales	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	ftsB	-	-	ko:K05589	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
k59_238859_1	1537917.JU82_06370	3.11e-98	298.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,42M94@68525|delta/epsilon subdivisions,2YMQM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
k59_1237508_1	1168067.JAGP01000001_gene720	4.19e-100	298.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,1RMHI@1236|Gammaproteobacteria,460EY@72273|Thiotrichales	72273|Thiotrichales	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
k59_1237508_2	1122201.AUAZ01000003_gene2007	1.7e-104	321.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,1RPFB@1236|Gammaproteobacteria,465YM@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0006950,GO:0006970,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009268,GO:0009409,GO:0009628,GO:0009651,GO:0009987,GO:0010467,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0042802,GO:0043021,GO:0043023,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0050896,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
k59_533414_2	387093.SUN_2277	5.75e-49	161.0	COG0666@1|root,COG0666@2|Bacteria,1Q2UY@1224|Proteobacteria,42WAJ@68525|delta/epsilon subdivisions,2YQKP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_4,Ank_5
k59_1824967_1	1249480.B649_01725	1.14e-178	509.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,42NGE@68525|delta/epsilon subdivisions,2YN37@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0471 Di- and tricarboxylate	-	-	-	ko:K03319	-	-	-	-	ko00000	2.A.47	-	-	Na_sulph_symp
k59_1824967_2	1249480.B649_01720	5.91e-30	118.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	CBM_3,CBM_X2,Cadherin_3,Cohesin
k59_1548887_1	1537917.JU82_04945	5.51e-122	359.0	COG1944@1|root,COG1944@2|Bacteria,1MV7K@1224|Proteobacteria,42M8K@68525|delta/epsilon subdivisions,2YMZN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	YcaO cyclodehydratase, ATP-ad Mg2+-binding	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	YcaO
k59_1779876_1	159087.Daro_3776	6.56e-98	296.0	2C4IG@1|root,2Z8A1@2|Bacteria,1QTHZ@1224|Proteobacteria,2VN98@28216|Betaproteobacteria,2KVXJ@206389|Rhodocyclales	206389|Rhodocyclales	S	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1329
k59_139255_1	649754.HMPREF0281_01205	1.47e-12	67.8	COG0127@1|root,COG0127@2|Bacteria,2GM2B@201174|Actinobacteria,22JQF@1653|Corynebacteriaceae	201174|Actinobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
k59_1137472_1	1537917.JU82_05055	2.33e-91	278.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,42MYS@68525|delta/epsilon subdivisions,2YMZ5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
k59_1842578_1	1249480.B649_11640	9.95e-110	332.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,42MEM@68525|delta/epsilon subdivisions,2YMWQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
k59_193767_2	1537917.JU82_06955	0.000199	43.1	COG0176@1|root,COG0176@2|Bacteria,1N9G3@1224|Proteobacteria,42MCK@68525|delta/epsilon subdivisions,2YMRY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
k59_1551219_1	1249480.B649_10625	1.09e-127	374.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,42MG2@68525|delta/epsilon subdivisions,2YMJH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
k59_195740_1	1537917.JU82_09295	5.5e-43	145.0	COG0352@1|root,COG0352@2|Bacteria,1Q57E@1224|Proteobacteria,42T8S@68525|delta/epsilon subdivisions,2YPQM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Thiamine monophosphate synthase	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
k59_1370985_1	159087.Daro_1451	2.87e-43	151.0	COG0426@1|root,COG0426@2|Bacteria,1NDXY@1224|Proteobacteria,2VKXD@28216|Betaproteobacteria,2KW04@206389|Rhodocyclales	206389|Rhodocyclales	C	Metallo-beta-lactamase superfamily	-	-	1.6.3.4	ko:K22405	-	-	-	-	ko00000,ko01000	-	-	-	Flavodoxin_1,Lactamase_B
k59_1370985_2	159087.Daro_1452	4.02e-89	263.0	COG1393@1|root,COG1393@2|Bacteria,1MZ7Z@1224|Proteobacteria,2VT4B@28216|Betaproteobacteria,2KX0K@206389|Rhodocyclales	206389|Rhodocyclales	P	ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	ArsC
k59_1370985_3	159087.Daro_1453	1.46e-62	191.0	COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,2VW4D@28216|Betaproteobacteria,2KX5U@206389|Rhodocyclales	206389|Rhodocyclales	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
k59_1370985_4	159087.Daro_1454	6.83e-66	213.0	COG0535@1|root,COG1433@1|root,COG0535@2|Bacteria,COG1433@2|Bacteria,1MWDC@1224|Proteobacteria,2VJBQ@28216|Betaproteobacteria,2KV00@206389|Rhodocyclales	206389|Rhodocyclales	C	Dinitrogenase iron-molybdenum cofactor	-	-	-	ko:K02585	-	-	-	-	ko00000	-	-	-	Nitro_FeMo-Co,Radical_SAM
k59_1258169_1	159087.Daro_0634	1.24e-139	409.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,2VHKQ@28216|Betaproteobacteria,2KV0F@206389|Rhodocyclales	206389|Rhodocyclales	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
k59_1258169_2	159087.Daro_0635	1.03e-83	251.0	COG2928@1|root,COG2928@2|Bacteria,1MWT5@1224|Proteobacteria,2VH65@28216|Betaproteobacteria,2KV5C@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
k59_1489002_1	1168067.JAGP01000001_gene1630	3.19e-236	662.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,1RP81@1236|Gammaproteobacteria,45ZX7@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
k59_1489002_2	717773.Thicy_0454	4.03e-84	262.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,1RMT8@1236|Gammaproteobacteria,45ZZA@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
k59_671107_1	90813.JQMT01000001_gene2033	2.8e-31	117.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,1RMAE@1236|Gammaproteobacteria,461M1@72273|Thiotrichales	72273|Thiotrichales	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	-	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
k59_671107_2	566466.NOR53_2217	7.64e-34	125.0	COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,1RPTB@1236|Gammaproteobacteria,1J54F@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Catabolite gene activator and regulatory subunit of cAMP-dependent protein	anr	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	Crp,HTH_Crp_2,cNMP_binding
k59_1433572_1	1172190.M947_08360	7.63e-69	223.0	COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,42M3J@68525|delta/epsilon subdivisions,2YMF8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
k59_1078656_1	1165841.SULAR_00830	1.11e-100	300.0	COG0679@1|root,COG0679@2|Bacteria,1N5NC@1224|Proteobacteria,42PYE@68525|delta/epsilon subdivisions,2YMUI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM Auxin Efflux Carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
k59_493097_1	1249480.B649_03445	4.21e-08	53.9	COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,42MAU@68525|delta/epsilon subdivisions,2YMBU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgI	-	-	ko:K02394	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgI
k59_493097_2	1537917.JU82_09170	3.36e-71	218.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,42U1F@68525|delta/epsilon subdivisions,2YP4X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	methyltransferase	rsmD	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth95
k59_76320_1	1123514.KB905902_gene227	1.56e-158	456.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,4603T@72273|Thiotrichales	72273|Thiotrichales	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
k59_76320_2	1123514.KB905902_gene228	4.22e-119	349.0	COG0277@1|root,COG0277@2|Bacteria,1MVYV@1224|Proteobacteria,1RN4G@1236|Gammaproteobacteria,462E0@72273|Thiotrichales	72273|Thiotrichales	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_4
k59_783315_1	929558.SMGD1_2679	1.06e-100	311.0	COG0726@1|root,COG1649@1|root,COG0726@2|Bacteria,COG1649@2|Bacteria,1MWR2@1224|Proteobacteria,43AG1@68525|delta/epsilon subdivisions,2YT1V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Hypothetical glycosyl hydrolase family 13	-	-	-	ko:K11931	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000	-	-	-	GHL13,Polysacc_deac_1
k59_1844919_1	1304883.KI912532_gene2153	2.92e-24	100.0	COG0591@1|root,COG0642@1|root,COG0591@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,2VKRS@28216|Betaproteobacteria,2KUB6@206389|Rhodocyclales	206389|Rhodocyclales	ET	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_1844919_2	62928.azo2411	4.61e-58	182.0	COG0745@1|root,COG0745@2|Bacteria,1RHCU@1224|Proteobacteria,2VT7U@28216|Betaproteobacteria,2KWBT@206389|Rhodocyclales	206389|Rhodocyclales	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_1489040_1	1537917.JU82_07440	1.35e-53	174.0	COG0515@1|root,COG0515@2|Bacteria,1R91D@1224|Proteobacteria,42XMS@68525|delta/epsilon subdivisions,2YT4X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KLT	Lipopolysaccharide kinase (Kdo/WaaP) family	-	-	-	-	-	-	-	-	-	-	-	-	Kdo
k59_1489040_2	1537917.JU82_07435	2.62e-57	186.0	COG0859@1|root,COG0859@2|Bacteria,1N5A1@1224|Proteobacteria,42S5Z@68525|delta/epsilon subdivisions,2YP6I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG0859 ADP-heptose LPS heptosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
k59_1781690_1	879212.DespoDRAFT_00219	1.4e-108	321.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,42MBM@68525|delta/epsilon subdivisions,2WJKG@28221|Deltaproteobacteria,2MMK7@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Transketolase, pyrimidine binding domain	pdhB	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2753	Transket_pyr,Transketolase_C
k59_1194419_1	159087.Daro_1542	1.82e-72	241.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KV5K@206389|Rhodocyclales	206389|Rhodocyclales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,dCache_1
k59_1194419_2	159087.Daro_1543	1.7e-25	100.0	COG1309@1|root,COG1309@2|Bacteria,1RDIM@1224|Proteobacteria,2VJQ5@28216|Betaproteobacteria,2KV0G@206389|Rhodocyclales	206389|Rhodocyclales	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_1139458_1	1537917.JU82_03990	9.6e-166	475.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,42N6C@68525|delta/epsilon subdivisions,2YMY6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
k59_141330_1	709032.Sulku_1740	2.59e-18	81.6	COG2063@1|root,COG2063@2|Bacteria,1RDEY@1224|Proteobacteria,42MJW@68525|delta/epsilon subdivisions,2YN3R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgH	-	-	ko:K02393	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgH
k59_141330_2	1537917.JU82_07665	6.86e-78	234.0	COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,42SH8@68525|delta/epsilon subdivisions,2YPDX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	GatB Yqey family protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
k59_493142_1	326298.Suden_1949	1.95e-36	130.0	2ESN2@1|root,33K6N@2|Bacteria,1P1DC@1224|Proteobacteria,4303W@68525|delta/epsilon subdivisions,2YRUC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_493142_2	1045855.DSC_08335	1.95e-09	59.3	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,1RMDA@1236|Gammaproteobacteria,1X3EU@135614|Xanthomonadales	135614|Xanthomonadales	M	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_1078700_1	1249480.B649_00020	6.62e-114	339.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1RGCV@1224|Proteobacteria,42M47@68525|delta/epsilon subdivisions,2YMRS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	(EAL) domain protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_431133_1	395494.Galf_2659	3.76e-92	280.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,2VH9J@28216|Betaproteobacteria,44V8B@713636|Nitrosomonadales	28216|Betaproteobacteria	F	PFAM Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
k59_1551356_1	159087.Daro_1851	2.17e-85	275.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,2KYCC@206389|Rhodocyclales	206389|Rhodocyclales	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.9	ko:K01539	ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978	-	-	-	ko00000,ko00001,ko01000,ko04147	3.A.3.1	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
k59_671206_1	387093.SUN_1578	1.52e-56	184.0	COG0490@1|root,COG1226@1|root,COG0490@2|Bacteria,COG1226@2|Bacteria,1QZ28@1224|Proteobacteria,42SQ1@68525|delta/epsilon subdivisions,2YTC0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	TrkA-N domain	-	-	-	-	-	-	-	-	-	-	-	-	TrkA_N
k59_671206_2	326298.Suden_1332	9.76e-16	81.6	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,42MW6@68525|delta/epsilon subdivisions,2YNJR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	potassium channel protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans,Ion_trans_2,TrkA_C,TrkA_N
k59_1309151_1	305700.B447_08938	1.19e-39	138.0	COG0637@1|root,COG0637@2|Bacteria,1QTWD@1224|Proteobacteria,2VNTW@28216|Betaproteobacteria,2KW3U@206389|Rhodocyclales	206389|Rhodocyclales	S	Pyrimidine 5''-nucleotidase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
k59_1309151_2	159087.Daro_0629	1.86e-89	269.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,2VIIY@28216|Betaproteobacteria,2KVGB@206389|Rhodocyclales	206389|Rhodocyclales	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
k59_371043_2	1537917.JU82_08055	4.66e-82	248.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,42N84@68525|delta/epsilon subdivisions,2YM7V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0510	DapB_C,DapB_N
k59_141348_1	1249480.B649_11255	2.38e-130	386.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,42MEI@68525|delta/epsilon subdivisions,2YN3Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Asparagine synthase, glutamine-hydrolyzing	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_961819_1	159087.Daro_2793	8.37e-48	159.0	COG3384@1|root,COG3384@2|Bacteria,1MXJZ@1224|Proteobacteria,2VIC3@28216|Betaproteobacteria,2KVN7@206389|Rhodocyclales	206389|Rhodocyclales	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	ygiD	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
k59_961819_2	159087.Daro_2792	1.24e-38	136.0	COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,2VK4X@28216|Betaproteobacteria,2KVET@206389|Rhodocyclales	206389|Rhodocyclales	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_1665162_1	1537917.JU82_08930	2.05e-19	82.0	COG0792@1|root,COG0792@2|Bacteria,1Q27V@1224|Proteobacteria,42V4E@68525|delta/epsilon subdivisions,2YQJM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
k59_1723227_1	713586.KB900536_gene442	2.24e-104	314.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,1RMUI@1236|Gammaproteobacteria,1WWD4@135613|Chromatiales	135613|Chromatiales	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
k59_255886_1	1249480.B649_03145	1.34e-95	294.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42P4R@68525|delta/epsilon subdivisions,2YM92@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	DUF3365,MCPsignal
k59_1194488_1	1488328.JMCL01000113_gene3381	1.18e-05	50.4	COG2199@1|root,COG3706@2|Bacteria,1RCJQ@1224|Proteobacteria,1RQUA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_671273_2	709032.Sulku_1923	6.93e-48	164.0	COG0795@1|root,COG0795@2|Bacteria,1PXEK@1224|Proteobacteria,42MVG@68525|delta/epsilon subdivisions,2YN6F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	permease	-	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_1139523_1	709032.Sulku_0305	2.06e-292	815.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2YMNT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_1605611_1	290398.Csal_2023	1.38e-11	68.6	COG0835@1|root,COG0835@2|Bacteria,1RD1W@1224|Proteobacteria,1S26J@1236|Gammaproteobacteria,1XKDU@135619|Oceanospirillales	135619|Oceanospirillales	NT	Chemotaxis signal transduction protein	cheW	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
k59_493214_1	159087.Daro_2679	3.05e-48	163.0	COG2404@1|root,COG2404@2|Bacteria,1MXEH@1224|Proteobacteria,2VKWK@28216|Betaproteobacteria,2KX23@206389|Rhodocyclales	206389|Rhodocyclales	S	Phosphoesterase DHHA1	-	-	-	-	-	-	-	-	-	-	-	-	DHHA1
k59_493214_2	452638.Pnec_1134	4.12e-14	67.0	COG2900@1|root,COG2900@2|Bacteria,1NGFM@1224|Proteobacteria,2VW0H@28216|Betaproteobacteria,1KB5Z@119060|Burkholderiaceae	28216|Betaproteobacteria	S	SlyX family	slyX	-	-	ko:K03745	-	-	-	-	ko00000	-	-	-	SlyX
k59_1194508_1	709032.Sulku_0670	9.55e-81	253.0	COG0265@1|root,COG0750@1|root,COG0265@2|Bacteria,COG0750@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2YMQT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
k59_371102_1	983917.RGE_16920	5.5e-38	136.0	COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,2VJTA@28216|Betaproteobacteria,1KKEX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	fliC	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_IN,Flagellin_N
k59_961904_2	694440.JOMF01000009_gene737	5.56e-14	69.3	arCOG05710@1|root,arCOG05710@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1605640_2	1537917.JU82_02655	3.77e-13	63.2	2A4UE@1|root,30TFZ@2|Bacteria,1PDA5@1224|Proteobacteria,42WVN@68525|delta/epsilon subdivisions,2YQRH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_255947_1	1123517.JOMR01000001_gene1258	1.43e-47	163.0	COG0688@1|root,COG0688@2|Bacteria,1MVT4@1224|Proteobacteria,1RN1U@1236|Gammaproteobacteria,460DD@72273|Thiotrichales	72273|Thiotrichales	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
k59_1665235_1	1276756.AUEX01000029_gene2176	2.07e-81	246.0	COG0066@1|root,COG0066@2|Bacteria,1R6KV@1224|Proteobacteria,2VNV8@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD2	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
k59_961926_1	159087.Daro_1851	6.81e-83	269.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,2KYCC@206389|Rhodocyclales	206389|Rhodocyclales	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.9	ko:K01539	ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978	-	-	-	ko00000,ko00001,ko01000,ko04147	3.A.3.1	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
k59_783508_2	1537917.JU82_10935	7.85e-76	246.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2YN0B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
k59_1489176_1	709032.Sulku_0181	3.5e-32	115.0	COG2078@1|root,COG2078@2|Bacteria,1Q5PY@1224|Proteobacteria,431KR@68525|delta/epsilon subdivisions,2YSE9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	AMMECR1	-	-	-	ko:K09141	-	-	-	-	ko00000	-	-	-	AMMECR1
k59_1489176_2	1537917.JU82_06850	2.84e-45	153.0	COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,42NGR@68525|delta/epsilon subdivisions,2YMH4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
k59_196010_1	709032.Sulku_0178	5.05e-109	335.0	COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,1MUFZ@1224|Proteobacteria,42MM9@68525|delta/epsilon subdivisions,2YMH2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
k59_961948_1	502025.Hoch_3144	1.35e-29	114.0	COG0395@1|root,COG0395@2|Bacteria,1N4I0@1224|Proteobacteria,42S2T@68525|delta/epsilon subdivisions,2WNIH@28221|Deltaproteobacteria,2YTVZ@29|Myxococcales	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	thuG	-	-	ko:K02026,ko:K10238	ko02010,map02010	M00204,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.17	-	-	BPD_transp_1
k59_961948_2	1479237.JMLY01000001_gene218	3.81e-15	74.3	COG1175@1|root,COG1175@2|Bacteria,1MWB7@1224|Proteobacteria,1RZC6@1236|Gammaproteobacteria,46DHU@72275|Alteromonadaceae	1236|Gammaproteobacteria	U	Binding-protein-dependent transport system inner membrane component	thuF	-	-	ko:K02025,ko:K10237	ko02010,map02010	M00204,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.17	-	-	BPD_transp_1
k59_1024549_1	96561.Dole_2088	3.62e-19	85.5	COG1403@1|root,COG1403@2|Bacteria,1PAQC@1224|Proteobacteria	1224|Proteobacteria	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_2
k59_1024549_2	1111732.AZOD01000001_gene1693	5.4e-14	73.9	COG0732@1|root,COG0732@2|Bacteria,1RHRY@1224|Proteobacteria,1S6NB@1236|Gammaproteobacteria,1XAAD@135614|Xanthomonadales	135614|Xanthomonadales	V	Type I restriction modification DNA specificity domain	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
k59_609568_1	709032.Sulku_2378	1.36e-121	356.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,42MFM@68525|delta/epsilon subdivisions,2YMJU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
k59_783550_1	709032.Sulku_1452	6.12e-104	321.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YNJ4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_1258490_1	1000565.METUNv1_00238	1.66e-10	57.8	2EHWE@1|root,33BMZ@2|Bacteria,1NGH4@1224|Proteobacteria,2VY0S@28216|Betaproteobacteria,2KXKQ@206389|Rhodocyclales	206389|Rhodocyclales	S	Putative motility protein	-	-	-	-	-	-	-	-	-	-	-	-	YjfB_motility
k59_1258490_2	159087.Daro_4137	6.04e-51	167.0	COG2267@1|root,COG2267@2|Bacteria,1QVBZ@1224|Proteobacteria,2VNI1@28216|Betaproteobacteria,2KUFT@206389|Rhodocyclales	206389|Rhodocyclales	I	Alpha beta hydrolase	-	-	1.11.1.10	ko:K00433	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_6
k59_783557_1	1232683.ADIMK_3919	1.96e-53	181.0	COG0457@1|root,COG0457@2|Bacteria,1N01S@1224|Proteobacteria	1224|Proteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1024601_1	159087.Daro_0559	2.29e-103	329.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,2VH3F@28216|Betaproteobacteria,2KUJ2@206389|Rhodocyclales	206389|Rhodocyclales	L	DNA polymerase III alpha subunit	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k59_783568_3	1537917.JU82_00495	2.45e-132	377.0	COG1351@1|root,COG1351@2|Bacteria,1Q73I@1224|Proteobacteria,42N3X@68525|delta/epsilon subdivisions,2YMHF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
k59_196066_1	1304883.KI912532_gene416	3.13e-73	240.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,2KUPC@206389|Rhodocyclales	206389|Rhodocyclales	T	COG2202 FOG PAS PAC domain	-	-	-	ko:K03776	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,PAS_3,TarH
k59_76520_1	1249480.B649_00050	8.69e-85	267.0	COG2199@1|root,COG2200@1|root,COG3620@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,COG3620@2|Bacteria,1MVJY@1224|Proteobacteria,42N7E@68525|delta/epsilon subdivisions,2YNE7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PFAM EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF
k59_1024613_1	929558.SMGD1_0421	1.35e-05	46.2	COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,42QRU@68525|delta/epsilon subdivisions,2YMXG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	ABC transporter	-	-	-	ko:K15555,ko:K15578	ko00910,ko00920,ko02010,map00910,map00920,map02010	M00436,M00438	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.16.1,3.A.1.17.2	-	-	ABC_tran
k59_1024613_2	317025.Tcr_0040	1.19e-78	236.0	COG1513@1|root,COG1513@2|Bacteria,1R9X0@1224|Proteobacteria,1S40B@1236|Gammaproteobacteria,460XE@72273|Thiotrichales	72273|Thiotrichales	P	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide	cynS	-	4.2.1.104	ko:K01725	ko00910,map00910	-	R03546,R10079	RC00952	ko00000,ko00001,ko01000	-	-	-	Cyanate_lyase
k59_312559_1	159087.Daro_0765	6.54e-07	48.9	COG1886@1|root,COG1886@2|Bacteria,1RGWT@1224|Proteobacteria,2VSZ7@28216|Betaproteobacteria,2KWB5@206389|Rhodocyclales	206389|Rhodocyclales	N	Flagellar motor switch	fliN	-	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FliMN_C
k59_312559_2	159087.Daro_0766	7.31e-98	293.0	COG1868@1|root,COG1868@2|Bacteria,1MX01@1224|Proteobacteria,2VI0A@28216|Betaproteobacteria,2KV75@206389|Rhodocyclales	206389|Rhodocyclales	N	flagellar motor switch protein	fliM	-	-	ko:K02416	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliM,FliMN_C
k59_197598_1	159087.Daro_3783	1.75e-47	159.0	COG4569@1|root,COG4569@2|Bacteria,1MV23@1224|Proteobacteria,2VMVU@28216|Betaproteobacteria,2KV1Q@206389|Rhodocyclales	206389|Rhodocyclales	Q	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds	-	-	1.2.1.10,1.2.1.87	ko:K18366	ko00362,ko00620,ko00621,ko00622,ko00650,ko01100,ko01120,ko01220,map00362,map00620,map00621,map00622,map00650,map01100,map01120,map01220	M00569	R00228,R01172,R09097	RC00004,RC00184,RC01195	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	AcetDehyd-dimer,Semialdhyde_dh
k59_197598_2	159087.Daro_3784	3.8e-91	272.0	COG1028@1|root,COG1028@2|Bacteria,1MUWC@1224|Proteobacteria,2VK5Z@28216|Betaproteobacteria,2KV3T@206389|Rhodocyclales	206389|Rhodocyclales	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k59_1666518_1	159087.Daro_0960	8.95e-142	419.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,2VJ2J@28216|Betaproteobacteria,2KUJW@206389|Rhodocyclales	206389|Rhodocyclales	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
k59_1724525_1	1537917.JU82_10820	3.98e-142	407.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,42MVI@68525|delta/epsilon subdivisions,2YMGY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	aldo keto reductase	tas	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_1080299_1	1165841.SULAR_01563	2.38e-173	497.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42Z0P@68525|delta/epsilon subdivisions,2YR4F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG0513 Superfamily II DNA and RNA	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k59_1080299_2	387093.SUN_1466	9.4e-20	82.8	2A8RF@1|root,30XU4@2|Bacteria,1PJNS@1224|Proteobacteria,42XNT@68525|delta/epsilon subdivisions,2YQP1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1798152_1	1165841.SULAR_08187	2.72e-165	490.0	COG0249@1|root,COG1403@1|root,COG0249@2|Bacteria,COG1403@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2YN6Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DNA mismatch repair MutS family	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_III,MutS_V
k59_1212440_1	879212.DespoDRAFT_00215	2.37e-136	402.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,42N8Y@68525|delta/epsilon subdivisions,2WIR7@28221|Deltaproteobacteria,2MHP6@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Pyridine nucleotide-disulphide oxidoreductase, FAD NAD(P)-binding domain, pyridine nucleotide-disulfide oxidoreductase dimerization region, FAD-dependent pyridine nucleotide-disulfide oxidoreductase	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
k59_734845_1	1304883.KI912532_gene1681	3.05e-124	366.0	COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,2VH2B@28216|Betaproteobacteria,2KVS2@206389|Rhodocyclales	206389|Rhodocyclales	V	extrusion protein MatE	norM	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
k59_1279425_1	159087.Daro_1028	1.94e-92	291.0	COG4206@1|root,COG4206@2|Bacteria,1QUWU@1224|Proteobacteria,2WGQG@28216|Betaproteobacteria,2KV16@206389|Rhodocyclales	206389|Rhodocyclales	H	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_1681858_1	387093.SUN_2275	2.53e-150	433.0	COG3746@1|root,COG3746@2|Bacteria,1MV8P@1224|Proteobacteria,42VG8@68525|delta/epsilon subdivisions,2YR2X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Putative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_5
k59_1505560_1	944547.ABLL_1976	4.02e-198	553.0	COG0119@1|root,COG0119@2|Bacteria,1MVQG@1224|Proteobacteria,42WDS@68525|delta/epsilon subdivisions,2YRMK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds	-	-	4.1.3.39	ko:K01666	ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220	M00545,M00569	R00750	RC00307,RC00371	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
k59_1684595_2	383372.Rcas_4419	1.28e-28	118.0	COG0178@1|root,COG0178@2|Bacteria,2G60U@200795|Chloroflexi,3751P@32061|Chloroflexia	32061|Chloroflexia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_577101_2	159087.Daro_0732	6.25e-45	154.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,2VI13@28216|Betaproteobacteria,2KUJP@206389|Rhodocyclales	206389|Rhodocyclales	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
k59_1801044_1	1442598.JABW01000030_gene1395	1.53e-15	82.4	COG4191@1|root,COG5001@1|root,COG5002@1|root,COG4191@2|Bacteria,COG5001@2|Bacteria,COG5002@2|Bacteria,1MU2C@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GGDEF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9
k59_1049316_1	929558.SMGD1_2864	1.12e-48	173.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42P4R@68525|delta/epsilon subdivisions,2YM92@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	DUF3365,MCPsignal
k59_861577_1	290402.Cbei_1632	1.54e-32	127.0	COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,1TPHP@1239|Firmicutes,249MR@186801|Clostridia,36FKT@31979|Clostridiaceae	186801|Clostridia	KL	Belongs to the N(4) N(6)-methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase,ParBc
k59_389521_1	1537917.JU82_10465	2.14e-74	225.0	COG3585@1|root,COG3585@2|Bacteria	2|Bacteria	H	molybdate ion transport	-	-	3.6.3.29,3.6.3.55	ko:K02017,ko:K06857	ko02010,map02010	M00186,M00189	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.2,3.A.1.6.4,3.A.1.8	-	-	ABC_tran,TOBE
k59_328900_1	709032.Sulku_2497	8.23e-114	333.0	COG3439@1|root,COG3439@2|Bacteria,1PWY7@1224|Proteobacteria,42Y9J@68525|delta/epsilon subdivisions,2YRF7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1331150_1	709032.Sulku_0605	1.1e-89	274.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,42MMY@68525|delta/epsilon subdivisions,2YMDM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	dihydropteroate synthase	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
k59_1867934_1	358220.C380_07670	1.79e-121	353.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,2VHD0@28216|Betaproteobacteria,4A9M0@80864|Comamonadaceae	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
k59_1627495_1	1089551.KE386572_gene835	1.23e-27	118.0	COG2202@1|root,COG2203@1|root,COG3437@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3437@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,4BP62@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_38116_1	709032.Sulku_0655	1.17e-95	289.0	COG0245@1|root,COG1211@1|root,COG0245@2|Bacteria,COG1211@2|Bacteria,1MVHA@1224|Proteobacteria,42MJ6@68525|delta/epsilon subdivisions,2YMEK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF)	ispDF	-	2.7.7.60,4.6.1.12	ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
k59_1215574_1	1249480.B649_03515	4.51e-95	283.0	COG1792@1|root,COG1792@2|Bacteria,1QB26@1224|Proteobacteria,42MF4@68525|delta/epsilon subdivisions,2YNT9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Rod shape-determining protein MreC	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
k59_219027_1	1249480.B649_08165	1.47e-122	374.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,42MKB@68525|delta/epsilon subdivisions,2YMIZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
k59_1215579_1	1249480.B649_06650	1.77e-20	88.6	COG2199@1|root,COG2199@2|Bacteria,1Q4Z5@1224|Proteobacteria,4306K@68525|delta/epsilon subdivisions,2YRSF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	diguanylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_1684655_1	1249480.B649_08220	1.65e-107	320.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,42PDR@68525|delta/epsilon subdivisions,2YN5V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	a g-specific adenine glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
k59_1684655_2	1537917.JU82_04715	3.51e-51	166.0	2AYIJ@1|root,31QNB@2|Bacteria,1QN8F@1224|Proteobacteria,42T66@68525|delta/epsilon subdivisions,2YPFG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1684655_3	1537917.JU82_04710	1.87e-05	45.4	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,42MMC@68525|delta/epsilon subdivisions,2YMS8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the TtcA family	ttcA	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
k59_1049384_1	709032.Sulku_0394	2.57e-72	237.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YMHP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3
k59_1801125_1	1249480.B649_02430	3.44e-14	70.9	COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,42MBJ@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
k59_1162301_1	983328.AFGH01000001_gene1444	3.23e-25	97.1	COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,42QW5@68525|delta/epsilon subdivisions,2YNWG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
k59_1162301_2	387093.SUN_2329	1.09e-24	93.6	COG0255@1|root,COG0255@2|Bacteria,1Q5ZI@1224|Proteobacteria,42VCR@68525|delta/epsilon subdivisions,2YQ6C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
k59_1162301_3	387093.SUN_2330	2.33e-48	154.0	COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,42TNS@68525|delta/epsilon subdivisions,2YPV2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
k59_1162301_4	395019.Bmul_0259	2.72e-13	66.2	COG0093@1|root,COG0093@2|Bacteria,1RCWZ@1224|Proteobacteria,2VR2N@28216|Betaproteobacteria,1K6YJ@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
k59_162304_2	159087.Daro_3685	7.91e-66	209.0	COG3221@1|root,COG3221@2|Bacteria,1R4SK@1224|Proteobacteria,2VQN6@28216|Betaproteobacteria,2KW7Y@206389|Rhodocyclales	206389|Rhodocyclales	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
k59_274688_1	395494.Galf_2887	3.27e-202	597.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,44V8X@713636|Nitrosomonadales	28216|Betaproteobacteria	V	TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_38174_1	929558.SMGD1_1196	3.71e-40	152.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1MWRF@1224|Proteobacteria,42UA0@68525|delta/epsilon subdivisions	1224|Proteobacteria	U	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,PD40,TPR_10,TPR_12,TPR_16,TPR_7,TPR_8
k59_695799_2	1249480.B649_08685	8.11e-24	93.2	29KSI@1|root,307PY@2|Bacteria,1PX63@1224|Proteobacteria,433IG@68525|delta/epsilon subdivisions,2YSQ0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1331223_2	387093.SUN_1041	3.31e-124	364.0	COG1419@1|root,COG1419@2|Bacteria,1MUQW@1224|Proteobacteria,42NBF@68525|delta/epsilon subdivisions,2YN28@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar biosynthesis	flhF	-	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	SRP54
k59_695801_1	159087.Daro_3382	9.49e-111	320.0	COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,2VI59@28216|Betaproteobacteria,2KV7E@206389|Rhodocyclales	206389|Rhodocyclales	E	imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
k59_1575990_1	709032.Sulku_0540	8.74e-56	175.0	COG1917@1|root,COG1917@2|Bacteria,1N2JS@1224|Proteobacteria,42TP9@68525|delta/epsilon subdivisions,2YQ4J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
k59_1575990_2	1249480.B649_02685	1.77e-45	146.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2YPX8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Cold-shock protein	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k59_1575990_3	392500.Swoo_3507	7.54e-36	136.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2Q8P9@267890|Shewanellaceae	1236|Gammaproteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	5TM-5TMR_LYT,EAL,GGDEF,PAS,PAS_3,PAS_9,dCache_1
k59_987215_1	1249480.B649_11615	2.28e-07	51.6	COG0803@1|root,COG0803@2|Bacteria,1MVW9@1224|Proteobacteria,42MBX@68525|delta/epsilon subdivisions,2YQ8H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the bacterial solute-binding protein 9 family	-	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
k59_987215_2	1249480.B649_11610	5.53e-79	241.0	COG1121@1|root,COG1121@2|Bacteria,1MUDW@1224|Proteobacteria,42NI8@68525|delta/epsilon subdivisions,2YMKV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	ABC transporter	-	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
k59_1215660_1	159087.Daro_2187	1.39e-81	250.0	COG3913@1|root,COG3913@2|Bacteria,1P1K2@1224|Proteobacteria,2VI4H@28216|Betaproteobacteria,2KXIJ@206389|Rhodocyclales	206389|Rhodocyclales	S	Uncharacterized protein conserved in bacteria (DUF2094)	-	-	-	ko:K11890	ko02025,map02025	-	-	-	ko00000,ko00001,ko02044	-	-	-	DUF2094
k59_1099410_1	983917.RGE_11780	3.07e-11	62.8	COG2863@1|root,COG2863@2|Bacteria,1N7W9@1224|Proteobacteria,2VWKS@28216|Betaproteobacteria,1KMK0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	PFAM Cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
k59_1331264_1	40492.XP_007308200.1	2.66e-05	54.3	2CNC5@1|root,2QV54@2759|Eukaryota,39S8X@33154|Opisthokonta,3NW2N@4751|Fungi,3V4CT@5204|Basidiomycota,22567@155619|Agaricomycetes,3H0EZ@355688|Agaricomycetes incertae sedis	4751|Fungi	G	Pectate lyase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectate_lyase_3
k59_1508813_2	1537917.JU82_10450	7.06e-82	243.0	COG1145@1|root,COG1145@2|Bacteria,1Q4YJ@1224|Proteobacteria,4305G@68525|delta/epsilon subdivisions,2YRVT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_7
k59_1508813_3	1537917.JU82_10455	1.35e-78	234.0	COG1433@1|root,COG1433@2|Bacteria,1N05Z@1224|Proteobacteria,42VFK@68525|delta/epsilon subdivisions,2YQG3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Dinitrogenase iron-molybdenum cofactor biosynthesis protein	-	-	-	ko:K02596	-	-	-	-	ko00000	-	-	-	Nitro_FeMo-Co
k59_1282098_3	1172190.M947_03605	3.47e-51	164.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,42MB9@68525|delta/epsilon subdivisions,2YMN0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	IQ	reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_1282098_4	1165841.SULAR_10424	5.49e-63	204.0	COG0778@1|root,COG0778@2|Bacteria,1Q0G9@1224|Proteobacteria,42MWR@68525|delta/epsilon subdivisions,2YNCN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	TIGRFAM SagB-type dehydrogenase domain	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_922873_1	1249480.B649_00175	1.76e-68	216.0	COG0679@1|root,COG0679@2|Bacteria,1N5NC@1224|Proteobacteria,42PYE@68525|delta/epsilon subdivisions,2YMUI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM Auxin Efflux Carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
k59_1282106_1	1304883.KI912532_gene382	6.28e-66	224.0	COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,1QU90@1224|Proteobacteria,2VHNR@28216|Betaproteobacteria	28216|Betaproteobacteria	L	RecB family exonuclease	-	-	3.1.11.5	ko:K01144	-	-	-	-	ko00000,ko01000	-	-	-	PDDEXK_1
k59_1627625_2	709032.Sulku_1463	4.25e-19	84.3	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,42KZJ@68525|delta/epsilon subdivisions,2YMR0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
k59_219150_1	666681.M301_2410	3.57e-93	275.0	COG1309@1|root,COG1309@2|Bacteria,1MWF7@1224|Proteobacteria,2VQ4C@28216|Betaproteobacteria,2KKDC@206350|Nitrosomonadales	206350|Nitrosomonadales	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K05501	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	TetR_N
k59_1684777_1	709032.Sulku_1890	4.88e-61	206.0	COG0457@1|root,COG4783@1|root,COG0457@2|Bacteria,COG4783@2|Bacteria,1QV15@1224|Proteobacteria,42NKI@68525|delta/epsilon subdivisions,2YMKG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	COG0457 FOG TPR repeat	pflB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_6,TPR_8
k59_1684777_2	709032.Sulku_1891	2.8e-78	238.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,42QV4@68525|delta/epsilon subdivisions,2YMTK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
k59_329058_1	717772.THIAE_03180	7.03e-20	88.2	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,45ZQ6@72273|Thiotrichales	72273|Thiotrichales	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_329058_2	557598.LHK_00569	1.18e-37	127.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,2VTZH@28216|Betaproteobacteria,2KRK5@206351|Neisseriales	206351|Neisseriales	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
k59_329058_3	1304883.KI912532_gene2471	8.77e-91	271.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,2VJ3S@28216|Betaproteobacteria,2KUFK@206389|Rhodocyclales	206389|Rhodocyclales	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_219158_1	709032.Sulku_0374	1.4e-207	575.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,42MI2@68525|delta/epsilon subdivisions,2YMPY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
k59_1457905_1	1249480.B649_06535	1.06e-108	325.0	COG2710@1|root,COG2710@2|Bacteria,1MVY2@1224|Proteobacteria,42MMI@68525|delta/epsilon subdivisions,2YNPZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Nitrogenase protein alpha chain	-	-	1.18.6.1	ko:K02586	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_nitro
k59_1392378_1	709032.Sulku_1505	6.13e-84	269.0	COG2199@1|root,COG3706@2|Bacteria,1R1K2@1224|Proteobacteria,42YWW@68525|delta/epsilon subdivisions,2YR1I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Double sensory domain of two-component sensor kinase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_3
k59_807975_1	1249480.B649_11660	1.24e-93	283.0	COG2956@1|root,COG2956@2|Bacteria,1QUIS@1224|Proteobacteria,42M7G@68525|delta/epsilon subdivisions,2YMKN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_7,TPR_8
k59_1331350_1	709032.Sulku_1542	1.64e-33	121.0	297UU@1|root,2ZV1D@2|Bacteria,1MXFE@1224|Proteobacteria,430YU@68525|delta/epsilon subdivisions,2YS1X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1331350_2	944547.ABLL_1972	2.21e-12	65.5	2E3B5@1|root,32YAP@2|Bacteria,1N7KQ@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF2721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2721
k59_1627659_1	1537917.JU82_11355	1.64e-55	191.0	COG1629@1|root,COG4771@2|Bacteria,1QZTU@1224|Proteobacteria,43CNU@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1627659_2	709032.Sulku_0854	3.09e-28	102.0	2AQJX@1|root,31FST@2|Bacteria,1QDI5@1224|Proteobacteria,432NI@68525|delta/epsilon subdivisions,2YSH6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1627659_3	1249480.B649_07805	2.23e-132	386.0	COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,42P1M@68525|delta/epsilon subdivisions,2YN96@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Peptidase M48	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
k59_162426_1	159087.Daro_2524	1.16e-103	304.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,2VIND@28216|Betaproteobacteria,2KU8F@206389|Rhodocyclales	206389|Rhodocyclales	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
k59_922959_1	626887.J057_01589	9.87e-32	123.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,464EF@72275|Alteromonadaceae	1236|Gammaproteobacteria	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	GO:0000166,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016884,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	iECH74115_1262.ECH74115_3792,iECO111_1330.ECO111_3283,iECSP_1301.ECSP_3501,iECs_1301.ECs3423,iG2583_1286.G2583_3088,iJN746.PP_1037,ic_1306.c3080	AIRS_C,GATase_5
k59_922959_2	1123514.KB905899_gene1898	4.15e-81	259.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,1RPX3@1236|Gammaproteobacteria,461JQ@72273|Thiotrichales	72273|Thiotrichales	F	Belongs to the 5'-nucleotidase family	-	-	-	ko:K17224	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	5_nucleotid_C
k59_1049542_1	1537917.JU82_04345	4.82e-151	430.0	COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1RD7I@1224|Proteobacteria,42SM8@68525|delta/epsilon subdivisions,2YPEY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Response regulator receiver	-	-	-	ko:K03415	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CheW,Response_reg
k59_1801312_1	537013.CLOSTMETH_00578	1.18e-10	65.1	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,2480T@186801|Clostridia,3WGQU@541000|Ruminococcaceae	186801|Clostridia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1,5.1.1.18	ko:K01775,ko:K18348	ko00473,ko01100,ko01502,ko02020,map00473,map01100,map01502,map02020	M00652	R00401	RC00285	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	-	-	-	Acyl_transf_3,Ala_racemase_C,Ala_racemase_N
k59_1801312_2	95619.PM1_0204660	4.56e-15	74.3	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
k59_861830_2	1123355.JHYO01000008_gene2574	1.86e-12	65.5	COG0235@1|root,COG0235@2|Bacteria,1MW7B@1224|Proteobacteria,2U1NG@28211|Alphaproteobacteria,36Y7M@31993|Methylocystaceae	28211|Alphaproteobacteria	G	Class II Aldolase and Adducin N-terminal domain	fucA	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
k59_515049_1	1537917.JU82_02320	3.53e-57	196.0	COG1287@1|root,COG1287@2|Bacteria,1R8YG@1224|Proteobacteria,43BIB@68525|delta/epsilon subdivisions,2YT8Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Oligosaccharide transferase	-	-	2.4.99.18	ko:K07151	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	STT3
k59_515049_2	1536770.R50345_24415	3.29e-21	94.0	COG0451@1|root,COG0451@2|Bacteria,1V1S9@1239|Firmicutes,4HDRB@91061|Bacilli,26V3F@186822|Paenibacillaceae	91061|Bacilli	GM	NAD-dependent epimerase	cap5N	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,RmlD_sub_bind
k59_162471_1	709032.Sulku_0751	5.89e-110	320.0	COG0340@1|root,COG0340@2|Bacteria,1Q1NZ@1224|Proteobacteria,42RQM@68525|delta/epsilon subdivisions,2YP5C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	biotin acetyl-CoA-carboxylase ligase	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_LplA_LipB
k59_219237_1	488538.SAR116_2062	1.28e-26	107.0	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,2TQNR@28211|Alphaproteobacteria,4BPBH@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k59_219237_2	316055.RPE_0097	1.2e-24	100.0	COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,2U4QB@28211|Alphaproteobacteria,3JRDA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
k59_278231_1	343509.SG2024	1.04e-24	98.2	COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,1S96Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yqgF	GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
k59_278231_2	491952.Mar181_3067	5.86e-12	64.7	COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,1S3YV@1236|Gammaproteobacteria,1XJXU@135619|Oceanospirillales	135619|Oceanospirillales	K	Belongs to the UPF0301 (AlgH) family	algH	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
k59_165265_1	1249480.B649_07705	4.67e-191	539.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,42M7Y@68525|delta/epsilon subdivisions,2YMTB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	argininosuccinate lyase	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
k59_165300_2	1249480.B649_06385	4.82e-103	301.0	COG0125@1|root,COG0125@2|Bacteria,1R98D@1224|Proteobacteria,43B5Z@68525|delta/epsilon subdivisions,2YP5N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
k59_699161_1	1116375.VEJY3_08880	4.72e-81	247.0	28PY0@1|root,2ZCHU@2|Bacteria,1RH7X@1224|Proteobacteria,1SP5R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_414485_1	159087.Daro_4175	4.33e-113	330.0	COG4261@1|root,COG4261@2|Bacteria,1MVXJ@1224|Proteobacteria,2VHP0@28216|Betaproteobacteria,2KUNV@206389|Rhodocyclales	206389|Rhodocyclales	S	Bacterial lipid A biosynthesis acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Lip_A_acyltrans
k59_1060902_4	1249480.B649_02840	5.73e-72	219.0	2BQTZ@1|root,32JQR@2|Bacteria,1Q2FB@1224|Proteobacteria,431HI@68525|delta/epsilon subdivisions,2YS7I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1060902_5	1249480.B649_02835	1.93e-156	450.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,42M1K@68525|delta/epsilon subdivisions,2YMKR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the peptidase M24B family	pepQ	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
k59_591654_2	882.DVU_1762	1.25e-66	206.0	COG3304@1|root,COG3304@2|Bacteria,1RA96@1224|Proteobacteria,42SE2@68525|delta/epsilon subdivisions,2WPSP@28221|Deltaproteobacteria,2MBBG@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Inner membrane component domain	-	-	-	-	-	-	-	-	-	-	-	-	YccF
k59_591654_3	522373.Smlt0200	4.21e-31	114.0	COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,1S3PI@1236|Gammaproteobacteria,1X643@135614|Xanthomonadales	135614|Xanthomonadales	J	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
k59_1120449_1	396588.Tgr7_0199	9.56e-58	202.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,1RQ8B@1236|Gammaproteobacteria,1WXE6@135613|Chromatiales	135613|Chromatiales	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,PAS_8
k59_297520_2	709032.Sulku_2478	8.38e-79	245.0	COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,42M5D@68525|delta/epsilon subdivisions,2YN2D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
k59_1648346_1	1537917.JU82_00930	1.57e-36	129.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,42M3X@68525|delta/epsilon subdivisions,2YMCQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
k59_1648346_2	709032.Sulku_1854	1.32e-33	116.0	COG1758@1|root,COG1758@2|Bacteria	2|Bacteria	K	DNA-directed 5'-3' RNA polymerase activity	rpoZ	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
k59_1589901_1	1165841.SULAR_05758	9.08e-37	133.0	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,42M40@68525|delta/epsilon subdivisions,2YMGX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
k59_944404_1	159087.Daro_2103	4.21e-33	119.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,2VJJE@28216|Betaproteobacteria,2KUZD@206389|Rhodocyclales	206389|Rhodocyclales	N	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
k59_944404_2	159087.Daro_2102	1.39e-46	166.0	COG0811@1|root,COG0811@2|Bacteria,1QVBX@1224|Proteobacteria,2WGPD@28216|Betaproteobacteria,2KV1P@206389|Rhodocyclales	206389|Rhodocyclales	U	Domain of unknown function (DUF802)	-	-	-	-	-	-	-	-	-	-	-	-	DUF802
k59_6202_1	1537917.JU82_05055	2.35e-219	611.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,42MYS@68525|delta/epsilon subdivisions,2YMZ5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
k59_1531997_1	709032.Sulku_0862	4.47e-98	299.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,42MPK@68525|delta/epsilon subdivisions,2YMFX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,SurA_N_3
k59_1003105_1	1121374.KB891585_gene2428	0.000483	43.9	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,1RN6Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009380,GO:0009628,GO:0032991,GO:0042802,GO:0044424,GO:0044464,GO:0050896,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
k59_767018_1	709032.Sulku_0330	7.98e-103	309.0	COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,42KZP@68525|delta/epsilon subdivisions,2YMBP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG1055 Na H antiporter NhaD and related arsenite	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
k59_591723_1	1165841.SULAR_06838	2.26e-77	252.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2YMW4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_1120531_1	614083.AWQR01000033_gene2871	1.9e-59	207.0	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria,4AA9F@80864|Comamonadaceae	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_4,PAS_9,Response_reg
k59_1060973_1	583345.Mmol_0197	1.56e-104	313.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,2VIJF@28216|Betaproteobacteria,2KM12@206350|Nitrosomonadales	206350|Nitrosomonadales	C	Belongs to the citrate synthase family	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
k59_6257_1	709032.Sulku_2067	3e-56	194.0	COG0642@1|root,COG3850@1|root,COG2205@2|Bacteria,COG3850@2|Bacteria,1NRP8@1224|Proteobacteria,42Z1P@68525|delta/epsilon subdivisions,2YRFA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	HAMP domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k59_1707104_1	159087.Daro_2188	5.89e-110	348.0	COG3523@1|root,COG3523@2|Bacteria,1MV3D@1224|Proteobacteria,2VJ0M@28216|Betaproteobacteria,2KV24@206389|Rhodocyclales	206389|Rhodocyclales	S	function. A few members resemble the ImcF protein, which has been proposed to be involved in Vibrio cholerae cell surface reorganisation that results in increased adherence to epithelial cells line and increased conjugation frequency	-	-	-	ko:K11891	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	IcmF-related,IcmF_C,ImcF-related_N
k59_474752_1	1537917.JU82_09900	1.12e-13	70.1	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,42MMG@68525|delta/epsilon subdivisions,2YMCT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
k59_474752_2	1537917.JU82_09895	3.27e-161	454.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,42MM7@68525|delta/epsilon subdivisions,2YM87@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
k59_827045_1	717773.Thicy_1332	1.65e-122	360.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,1RNV6@1236|Gammaproteobacteria,45ZZ4@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
k59_1707113_1	1005048.CFU_0210	2.72e-70	236.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,2VJ61@28216|Betaproteobacteria,473R8@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_1120573_1	159087.Daro_0662	3.52e-110	329.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,2KUM4@206389|Rhodocyclales	206389|Rhodocyclales	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	pilR	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_827065_1	387093.SUN_0065	4.6e-111	331.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,42M6I@68525|delta/epsilon subdivisions,2YMNB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_180031_1	1249480.B649_08765	1.66e-217	616.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42N29@68525|delta/epsilon subdivisions,2YMFM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA helicase	rep	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_1120581_1	709032.Sulku_2195	1.14e-91	270.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,42QTK@68525|delta/epsilon subdivisions,2YNW0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
k59_1120581_2	1537917.JU82_08640	6.18e-53	169.0	2AHPN@1|root,3181V@2|Bacteria,1PZNU@1224|Proteobacteria,42QWU@68525|delta/epsilon subdivisions,2YMYS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF3972)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3972
k59_1532097_1	667632.KB890183_gene967	1.49e-71	224.0	COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,2VJ8E@28216|Betaproteobacteria,1K1F9@119060|Burkholderiaceae	28216|Betaproteobacteria	O	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate	ate	-	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	ATE_C,ATE_N
k59_1238393_1	1537917.JU82_11355	1.99e-212	613.0	COG1629@1|root,COG4771@2|Bacteria,1QZTU@1224|Proteobacteria,43CNU@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_239542_1	710393.HSUHS1_0927	1.33e-15	74.7	2CCD9@1|root,32NJ2@2|Bacteria,1Q3UE@1224|Proteobacteria,42XU5@68525|delta/epsilon subdivisions,2YQSW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	YtkA-like	-	-	-	-	-	-	-	-	-	-	-	-	YtkA
k59_1003198_1	159087.Daro_3649	6.16e-86	257.0	COG0664@1|root,COG0664@2|Bacteria,1R6BV@1224|Proteobacteria,2VN3A@28216|Betaproteobacteria,2KVAG@206389|Rhodocyclales	206389|Rhodocyclales	K	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	nnr	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
k59_944518_1	1249480.B649_08675	5.43e-22	90.1	COG1334@1|root,COG1334@2|Bacteria,1NH9T@1224|Proteobacteria,42X2H@68525|delta/epsilon subdivisions,2YR05@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	FlaG protein	-	-	-	ko:K06603	-	-	-	-	ko00000,ko02035	-	-	-	FlaG
k59_944518_2	177439.DP2720	3.34e-27	102.0	COG2827@1|root,COG2827@2|Bacteria,1N6PA@1224|Proteobacteria,42VGM@68525|delta/epsilon subdivisions,2WRJ4@28221|Deltaproteobacteria,2MQ0F@213118|Desulfobacterales	28221|Deltaproteobacteria	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
k59_944518_3	709032.Sulku_1077	1.96e-47	157.0	COG1514@1|root,COG1514@2|Bacteria,1Q2AV@1224|Proteobacteria,42VB6@68525|delta/epsilon subdivisions,2YQIV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	2'-5' RNA ligase	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
k59_1825758_1	159087.Daro_1133	3.86e-46	155.0	2CD15@1|root,32RWT@2|Bacteria,1N50G@1224|Proteobacteria,2W21P@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1120610_1	709032.Sulku_1439	3.05e-226	629.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,42MKY@68525|delta/epsilon subdivisions,2YMUR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
k59_1120610_2	1537917.JU82_05870	6.59e-16	72.4	COG1832@1|root,COG1832@2|Bacteria,1N03D@1224|Proteobacteria,42TZA@68525|delta/epsilon subdivisions,2YPC1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	CoA-binding protein	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
k59_944544_2	1122619.KB892303_gene881	3.13e-27	108.0	COG1373@1|root,COG1373@2|Bacteria,1R65E@1224|Proteobacteria	1224|Proteobacteria	S	ATPase (AAA)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14
k59_122319_1	159087.Daro_0874	9.55e-10	57.8	COG3147@1|root,COG3147@2|Bacteria,1R7IV@1224|Proteobacteria,2VPE1@28216|Betaproteobacteria,2KWXH@206389|Rhodocyclales	206389|Rhodocyclales	S	Sporulation related domain	-	-	-	ko:K03749	-	-	-	-	ko00000	-	-	-	SPOR
k59_122319_2	159087.Daro_0873	6.41e-83	258.0	COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,2VI0H@28216|Betaproteobacteria,2KV9G@206389|Rhodocyclales	206389|Rhodocyclales	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
k59_1532153_1	1479237.JMLY01000001_gene3051	3.15e-96	293.0	COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,1RN46@1236|Gammaproteobacteria,4644Z@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016782,GO:0018193,GO:0018197,GO:0018198,GO:0018339,GO:0019538,GO:0035596,GO:0035599,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901564	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
k59_1003256_1	1537917.JU82_08315	6.95e-143	411.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,42M5V@68525|delta/epsilon subdivisions,2YM81@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Cysteine desulfurase	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
k59_885394_1	1198452.Jab_2c01460	3.47e-80	249.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,2VHGK@28216|Betaproteobacteria,473T5@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
k59_1120642_1	1304883.KI912532_gene615	6.89e-64	206.0	COG1819@1|root,COG1819@2|Bacteria,1MVJM@1224|Proteobacteria,2VME8@28216|Betaproteobacteria,2KXTJ@206389|Rhodocyclales	206389|Rhodocyclales	CG	glycosyl	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1120642_2	159087.Daro_0172	1e-119	344.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,2VQC3@28216|Betaproteobacteria,2KWAG@206389|Rhodocyclales	206389|Rhodocyclales	D	Maf-like protein	-	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
k59_1413901_1	709032.Sulku_2312	5.64e-180	504.0	COG2857@1|root,COG2857@2|Bacteria,1PX4N@1224|Proteobacteria,42MFF@68525|delta/epsilon subdivisions,2YMBA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	ubiquinol cytochrome c oxidoreductase, cytochrome c1	petC	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	iIT341.HP1538	Cytochrom_C,Cytochrom_C1
k59_1061088_1	1411685.U062_01879	1.41e-08	62.0	COG5276@1|root,COG5276@2|Bacteria,1R8AF@1224|Proteobacteria,1S8X1@1236|Gammaproteobacteria,1JC20@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1296107_1	709032.Sulku_2491	1.73e-149	447.0	COG0243@1|root,COG0243@2|Bacteria,1NSXR@1224|Proteobacteria,43BQI@68525|delta/epsilon subdivisions,2YRHF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	ko:K17050	-	-	-	-	ko00000,ko02000	5.A.3.8	-	-	Molybdopterin,Molydop_binding
k59_708483_1	857087.Metme_1300	2.33e-32	130.0	COG3203@1|root,COG3203@2|Bacteria,1PNUI@1224|Proteobacteria,1TBPE@1236|Gammaproteobacteria,1XGP0@135618|Methylococcales	135618|Methylococcales	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1120701_1	387093.SUN_1696	1.31e-32	123.0	COG0457@1|root,COG4783@1|root,COG0457@2|Bacteria,COG4783@2|Bacteria,1Q55C@1224|Proteobacteria,42RCA@68525|delta/epsilon subdivisions,2YND3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	PPR
k59_1120701_2	1165841.SULAR_05413	1.88e-29	111.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,42MAG@68525|delta/epsilon subdivisions,2YM8T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the TrpC family	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
k59_63200_1	1249480.B649_01675	8.26e-119	342.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,42NC0@68525|delta/epsilon subdivisions,2YMP8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP1386	Ribul_P_3_epim
k59_885446_1	926569.ANT_25290	5.68e-63	217.0	COG0653@1|root,COG0653@2|Bacteria,2G603@200795|Chloroflexi	200795|Chloroflexi	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k59_1061121_1	159087.Daro_1016	1.96e-105	327.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,2VHXF@28216|Betaproteobacteria,2KU7U@206389|Rhodocyclales	206389|Rhodocyclales	M	penicillin-binding protein 1A	mcrA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
k59_1590122_1	1150621.SMUL_0080	1.66e-48	176.0	COG0715@1|root,COG0834@1|root,COG2199@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG2199@2|Bacteria,1RGCV@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	yeaI	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0032879,GO:0040012,GO:0040013,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051270,GO:0051271,GO:0065007,GO:0071944,GO:1902021,GO:1902201,GO:2000145,GO:2000146	2.7.7.65	ko:K20959	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_853	CHASE,EAL,GGDEF,MASE4,NMT1,PAS,PAS_3
k59_1413974_1	159087.Daro_0342	1.81e-76	228.0	COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,2VR2K@28216|Betaproteobacteria,2KWBI@206389|Rhodocyclales	206389|Rhodocyclales	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
k59_944657_1	713586.KB900536_gene1315	9.79e-31	119.0	COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,1RNFN@1236|Gammaproteobacteria,1WZY2@135613|Chromatiales	135613|Chromatiales	C	Aldehyde dehydrogenase family	-	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_944657_2	76114.ebA4615	1.42e-89	275.0	COG2379@1|root,COG2379@2|Bacteria,1MVIK@1224|Proteobacteria,2VHXK@28216|Betaproteobacteria,2KV3N@206389|Rhodocyclales	206389|Rhodocyclales	G	MOFRL family	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
k59_1296170_1	1122173.AXVL01000004_gene887	2.72e-10	63.2	COG4185@1|root,COG4185@2|Bacteria,37BI6@32066|Fusobacteria	32066|Fusobacteria	S	Zeta toxin	-	-	-	-	-	-	-	-	-	-	-	-	Zeta_toxin
k59_708514_1	749222.Nitsa_0304	2.6e-38	136.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,42MU6@68525|delta/epsilon subdivisions,2YMMA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iIT341.HP0202	ACP_syn_III,ACP_syn_III_C
k59_708514_2	1165841.SULAR_06908	3.81e-66	207.0	COG1692@1|root,COG1692@2|Bacteria,1MW12@1224|Proteobacteria,42PCG@68525|delta/epsilon subdivisions,2YN6X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	metallophosphoesterase	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
k59_6453_1	709032.Sulku_1164	2.56e-143	416.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,42M90@68525|delta/epsilon subdivisions,2YMR5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k59_6453_2	1249480.B649_04960	8.56e-102	305.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,42M0T@68525|delta/epsilon subdivisions,2YMEX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0183	SHMT
k59_239683_1	525898.Sdel_0959	3.7e-24	96.7	2EFB2@1|root,33941@2|Bacteria,1NPZU@1224|Proteobacteria,42VDZ@68525|delta/epsilon subdivisions,2YRYR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_239683_2	709032.Sulku_1511	4.76e-49	173.0	COG2199@1|root,COG2200@1|root,COG3287@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,COG3287@2|Bacteria,1NQKX@1224|Proteobacteria,43DAG@68525|delta/epsilon subdivisions,2YTHK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,FIST,FIST_C,GGDEF,PAS_9
k59_1825910_1	709032.Sulku_2489	7.55e-148	426.0	COG3474@1|root,COG3474@2|Bacteria,1R1KB@1224|Proteobacteria,42Z1J@68525|delta/epsilon subdivisions,2YRH9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome c-552 DMSO reductase-like, heme-binding domain	-	-	-	ko:K17052	-	-	-	-	ko00000,ko02000	5.A.3.8	-	-	Cytochrom_C,EB_dh
k59_1590172_1	1123393.KB891326_gene95	3e-100	301.0	COG1409@1|root,COG1409@2|Bacteria,1MV0H@1224|Proteobacteria,2WHIF@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
k59_767222_1	1249480.B649_07390	2.32e-52	187.0	COG2304@1|root,COG4932@1|root,COG5295@1|root,COG2304@2|Bacteria,COG4932@2|Bacteria,COG5295@2|Bacteria,1QU09@1224|Proteobacteria,43DI2@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,HemolysinCabind,VWA_2
k59_1238608_1	159087.Daro_0782	4.21e-12	67.8	COG1345@1|root,COG1345@2|Bacteria,1MUVP@1224|Proteobacteria,2VHMK@28216|Betaproteobacteria,2KUJB@206389|Rhodocyclales	206389|Rhodocyclales	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	-	-	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_IN,FliD_C,FliD_N
k59_1238608_2	983545.Glaag_1250	8.23e-09	56.2	COG1334@1|root,COG1334@2|Bacteria,1NH9T@1224|Proteobacteria,1SH7I@1236|Gammaproteobacteria,468X0@72275|Alteromonadaceae	1236|Gammaproteobacteria	N	flagellar protein FlaG	flaG	-	-	ko:K06603	-	-	-	-	ko00000,ko02035	-	-	-	FlaG
k59_1590177_1	709032.Sulku_2222	9.89e-98	303.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,43BJ8@68525|delta/epsilon subdivisions,2YMMJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	penicillin-binding protein	pbpA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
k59_1532294_1	1121035.AUCH01000005_gene50	3.45e-97	303.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,2VICG@28216|Betaproteobacteria,2KUWE@206389|Rhodocyclales	206389|Rhodocyclales	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
k59_415804_2	159087.Daro_2736	4.47e-130	374.0	COG2961@1|root,COG2961@2|Bacteria,1MWGA@1224|Proteobacteria,2VHM4@28216|Betaproteobacteria,2KUB4@206389|Rhodocyclales	206389|Rhodocyclales	J	Specifically methylates the adenine in position 2030 of 23S rRNA	rlmJ	-	2.1.1.266	ko:K07115	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RsmJ
k59_651904_1	717773.Thicy_0872	1.7e-89	282.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RMNZ@1236|Gammaproteobacteria,45ZSH@72273|Thiotrichales	72273|Thiotrichales	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k59_1005627_1	1523503.JPMY01000004_gene1641	7.41e-11	69.3	COG2199@1|root,COG3706@2|Bacteria,1MWHH@1224|Proteobacteria,1RRU7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,GGDEF
k59_8305_1	709032.Sulku_2034	2.13e-87	266.0	COG0409@1|root,COG0409@2|Bacteria,1MU1F@1224|Proteobacteria,42M6R@68525|delta/epsilon subdivisions,2YMQU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the HypD family	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
k59_8305_2	1249480.B649_03380	5.93e-40	134.0	arCOG07672@1|root,3290Q@2|Bacteria,1NJHB@1224|Proteobacteria,432QX@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Domain of unknown function (DUF4258)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4258
k59_8305_3	1121115.AXVN01000006_gene2175	1.63e-11	61.2	arCOG06833@1|root,32SGF@2|Bacteria,1U5WJ@1239|Firmicutes,25K3K@186801|Clostridia,3Y0UZ@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_887303_1	1249480.B649_01120	2.48e-56	186.0	COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,42N9J@68525|delta/epsilon subdivisions,2YMC3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Long-chain fatty acid transport protein	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k59_1430328_2	1182590.BN5_00023	2.79e-20	90.5	COG0144@1|root,COG0144@2|Bacteria,1MWPE@1224|Proteobacteria,1RN8X@1236|Gammaproteobacteria,1YE4T@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
k59_1548144_1	1537917.JU82_05125	1.72e-45	156.0	COG2199@1|root,COG3706@2|Bacteria,1QV14@1224|Proteobacteria,42NPJ@68525|delta/epsilon subdivisions,2YNH9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_1548144_2	1249480.B649_11720	2.43e-41	140.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,42RFN@68525|delta/epsilon subdivisions,2YP6C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
k59_553244_1	709032.Sulku_0967	0.000155	45.1	COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1N81M@1224|Proteobacteria,42TBG@68525|delta/epsilon subdivisions,2YPER@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	chemotaxis signal transduction protein	-	-	-	ko:K03415	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CheW,Response_reg
k59_553244_2	709032.Sulku_0968	7.13e-33	121.0	COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,4304D@68525|delta/epsilon subdivisions,2YRUQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	COGs COG0835 Chemotaxis signal transduction protein	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
k59_670333_1	159087.Daro_2448	3.39e-82	264.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,2VI1P@28216|Betaproteobacteria,2KUVE@206389|Rhodocyclales	206389|Rhodocyclales	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
k59_1781088_1	1249480.B649_04280	6.4e-97	294.0	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,42MJ9@68525|delta/epsilon subdivisions,2YNG4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
k59_900882_1	1208918.CDEE_0352	2.33e-09	57.8	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,2VHNX@28216|Betaproteobacteria,1KPTM@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
k59_900882_2	1304883.KI912532_gene284	2.02e-105	311.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,2VHHG@28216|Betaproteobacteria,2KUIY@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k59_311043_1	159087.Daro_0966	3.13e-87	278.0	COG2804@1|root,COG3437@1|root,COG2804@2|Bacteria,COG3437@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,2KVIS@206389|Rhodocyclales	206389|Rhodocyclales	NU	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Response_reg,T2SSE,T2SSE_N
k59_1078056_2	387093.SUN_0965	1.81e-81	250.0	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,42P2E@68525|delta/epsilon subdivisions,2YNPW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
k59_608756_1	748280.NH8B_2800	1.47e-96	284.0	COG0582@1|root,COG0582@2|Bacteria,1P1R9@1224|Proteobacteria,2VJ48@28216|Betaproteobacteria	28216|Betaproteobacteria	L	PFAM integrase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
k59_19672_1	1121035.AUCH01000007_gene460	1.29e-35	136.0	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria,2KVXP@206389|Rhodocyclales	206389|Rhodocyclales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,PAS_7,PAS_9,Response_reg
k59_19672_2	159087.Daro_0550	1.11e-27	105.0	COG1192@1|root,COG1192@2|Bacteria,1QBJX@1224|Proteobacteria,2VJNI@28216|Betaproteobacteria,2KVZM@206389|Rhodocyclales	206389|Rhodocyclales	D	ATPase MipZ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	CbiA
k59_1370437_1	1249480.B649_05060	4.3e-16	78.2	COG0840@1|root,COG0840@2|Bacteria,1R486@1224|Proteobacteria,42Q5Y@68525|delta/epsilon subdivisions,2YNT8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	CZB,MCPsignal
k59_75826_1	1548151.LS70_07595	1.66e-21	92.4	COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1R8DG@1224|Proteobacteria,42NGC@68525|delta/epsilon subdivisions,2YN3X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the ompA family	cadF	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA
k59_1023461_1	1249480.B649_10250	6.41e-137	409.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Histidine kinase A domain protein	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3,dCache_1
k59_255267_1	1537917.JU82_02235	1.2e-96	292.0	COG0577@1|root,COG0577@2|Bacteria,1QT4V@1224|Proteobacteria,42P7K@68525|delta/epsilon subdivisions,2YNGD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	ABC transporter permease	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
k59_1844207_2	709032.Sulku_1287	1.38e-33	121.0	COG2227@1|root,COG2227@2|Bacteria,1QYD8@1224|Proteobacteria,43CBI@68525|delta/epsilon subdivisions,2YTHI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Ribosomal RNA adenine dimethylase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
k59_1488576_1	322710.Avin_11940	6.7e-21	92.4	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,1RN7F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluD	GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432	PseudoU_synth_2,S4
k59_1432863_1	288000.BBta_5731	4.71e-40	149.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2TSN5@28211|Alphaproteobacteria,3JUXZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	4Fe-4S dicluster domain	MA20_43170	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8
k59_1308627_2	709032.Sulku_0097	5.9e-76	228.0	COG2010@1|root,COG2010@2|Bacteria,1NKKK@1224|Proteobacteria,42UAC@68525|delta/epsilon subdivisions,2YRSI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
k59_75850_1	1304883.KI912532_gene1214	3.22e-103	310.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,2KV3K@206389|Rhodocyclales	206389|Rhodocyclales	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	ntrC	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_900931_1	1165841.SULAR_02808	2.53e-80	259.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MHP@68525|delta/epsilon subdivisions,2YN92@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k59_1844215_1	1249480.B649_06365	2.17e-215	619.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YNS1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4
k59_1844215_2	1537917.JU82_11080	2.06e-28	104.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Thioredoxin
k59_1432869_1	1537917.JU82_06215	4.63e-84	256.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,42N1C@68525|delta/epsilon subdivisions,2YMUA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
k59_140731_1	1537917.JU82_09400	2.79e-53	185.0	COG0068@1|root,COG0068@2|Bacteria,1Q0S6@1224|Proteobacteria,42SF1@68525|delta/epsilon subdivisions,2YPJ0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	HypF finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HYPF
k59_19710_1	1537917.JU82_01000	8.9e-51	174.0	COG1956@1|root,COG3604@1|root,COG1956@2|Bacteria,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,42Y69@68525|delta/epsilon subdivisions,2YNEN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	Transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF_2,HTH_8,Sigma54_activat
k59_1488598_1	1537917.JU82_04795	5.88e-45	161.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,42MKB@68525|delta/epsilon subdivisions,2YMIZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
k59_140750_1	1278971.AOGF01000017_gene790	3.66e-09	54.3	COG1977@1|root,COG1977@2|Bacteria,1N0IE@1224|Proteobacteria,1S8S1@1236|Gammaproteobacteria,1Y91N@135625|Pasteurellales	135625|Pasteurellales	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
k59_140750_2	59538.XP_005974329.1	3.3e-39	135.0	COG0314@1|root,KOG3307@2759|Eukaryota	2759|Eukaryota	H	molybdopterin synthase activity	cnxH	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
k59_719948_2	1195246.AGRI_15290	1.86e-32	116.0	COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,1S8W3@1236|Gammaproteobacteria,467TU@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
k59_719948_3	1122197.ATWI01000008_gene3101	5.63e-06	46.6	COG1576@1|root,COG1576@2|Bacteria,1R9Z2@1224|Proteobacteria,1S1ZY@1236|Gammaproteobacteria,466GK@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046983,GO:0070037,GO:0070038,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
k59_608831_1	1249480.B649_00035	2.91e-73	236.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42N6Y@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE5,GAF,HATPase_c,HisKA,PAS_4,Response_reg,dCache_2,sCache_2
k59_1844251_1	159087.Daro_0577	9.08e-44	146.0	COG0717@1|root,COG0717@2|Bacteria,1MV2J@1224|Proteobacteria,2VIJ0@28216|Betaproteobacteria,2KU9E@206389|Rhodocyclales	206389|Rhodocyclales	F	Belongs to the dCTP deaminase family	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
k59_1193889_1	1537917.JU82_11480	3.21e-138	402.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,42M31@68525|delta/epsilon subdivisions,2YMGC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
k59_75887_1	1249480.B649_09220	1.72e-143	426.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,42M2T@68525|delta/epsilon subdivisions,2YMF5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	ATP-dependent CLP protease ATP-binding subunit	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_553423_1	1537917.JU82_08090	4.91e-120	352.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,42M0C@68525|delta/epsilon subdivisions,2YM8W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
k59_1844278_1	1249480.B649_08245	6.83e-103	303.0	COG2204@1|root,COG2204@2|Bacteria,1QASN@1224|Proteobacteria,42RV2@68525|delta/epsilon subdivisions,2YP76@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activ_2,Sigma54_activat
k59_19735_1	159087.Daro_1937	6.41e-23	90.5	COG0824@1|root,COG0824@2|Bacteria,1RGZN@1224|Proteobacteria,2WEH8@28216|Betaproteobacteria,2KWT4@206389|Rhodocyclales	206389|Rhodocyclales	S	Thioesterase superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT_2
k59_19735_2	159087.Daro_1938	2.77e-115	341.0	COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,2VI7B@28216|Betaproteobacteria,2KVNM@206389|Rhodocyclales	206389|Rhodocyclales	F	Belongs to the dGTPase family. Type 2 subfamily	dgt1	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
k59_1432943_1	1157708.KB907454_gene3100	7.66e-74	236.0	28H52@1|root,2Z7HQ@2|Bacteria,1MXTF@1224|Proteobacteria,2VJJ3@28216|Betaproteobacteria,4AAA4@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1329)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1329
k59_255345_1	383407.XOC_3864	2.67e-31	125.0	COG3754@1|root,COG3754@2|Bacteria,1MYA9@1224|Proteobacteria,1SFJJ@1236|Gammaproteobacteria,1XCTI@135614|Xanthomonadales	135614|Xanthomonadales	H	Rhamnan synthesis protein F	-	-	-	-	-	-	-	-	-	-	-	-	RgpF
k59_1193923_1	697282.Mettu_0993	9.79e-46	159.0	COG3385@1|root,COG3385@2|Bacteria,1NIWM@1224|Proteobacteria,1S5FT@1236|Gammaproteobacteria,1XFX0@135618|Methylococcales	135618|Methylococcales	L	PFAM Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
k59_1078185_1	387093.SUN_2101	1.84e-105	319.0	COG3581@1|root,COG3581@2|Bacteria,1R7UD@1224|Proteobacteria,42W9G@68525|delta/epsilon subdivisions,2YRJ6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	4 iron, 4 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1078185_2	317025.Tcr_0084	6.66e-19	83.6	COG2227@1|root,COG2227@2|Bacteria,1MY0S@1224|Proteobacteria,1RP69@1236|Gammaproteobacteria,460C4@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs	cmoM	-	-	ko:K06219	-	-	-	-	ko00000	-	-	-	Methyltransf_11
k59_195245_1	1217713.F993_03225	1.5e-85	263.0	COG4603@1|root,COG4603@2|Bacteria,1MX6V@1224|Proteobacteria,1RS4S@1236|Gammaproteobacteria,3NMIR@468|Moraxellaceae	1236|Gammaproteobacteria	S	Branched-chain amino acid transport system / permease component	IV02_22040	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
k59_311141_1	1249480.B649_01215	1.28e-108	340.0	COG0457@1|root,COG0457@2|Bacteria,1QV1A@1224|Proteobacteria,42MIW@68525|delta/epsilon subdivisions,2YMDB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Paralysed flagella protein	pflA	-	-	-	-	-	-	-	-	-	-	-	TPR_21,TPR_6,TPR_8,YfiO
k59_1844331_1	1165841.SULAR_06668	4.34e-103	303.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,42P96@68525|delta/epsilon subdivisions,2YTJM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	abc transporter atp-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_1722765_1	1191523.MROS_1375	6.91e-06	50.1	COG0778@1|root,COG0778@2|Bacteria	2|Bacteria	C	coenzyme F420-1:gamma-L-glutamate ligase activity	tdsD	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_961349_1	1537917.JU82_01980	1.06e-129	374.0	COG1013@1|root,COG1013@2|Bacteria,1MUY9@1224|Proteobacteria,42MQY@68525|delta/epsilon subdivisions,2YMWJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	pyruvate ferredoxin oxidoreductase	porB	-	1.2.7.1	ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
k59_75939_1	709032.Sulku_1408	2.38e-88	275.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,42N7A@68525|delta/epsilon subdivisions,2YMRE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	lytic murein transglycosylase	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
k59_961358_1	1249480.B649_05980	9.09e-69	228.0	COG2319@1|root,COG2319@2|Bacteria,1Q4XR@1224|Proteobacteria,42PRP@68525|delta/epsilon subdivisions,2YMZB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	WD40
k59_311174_1	396588.Tgr7_1722	3.21e-32	122.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RP0W@1236|Gammaproteobacteria,1WWIR@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_311174_2	1249480.B649_07770	2.94e-113	339.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,42MPK@68525|delta/epsilon subdivisions,2YMFX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,SurA_N_3
k59_901060_2	1249627.D779_0697	2.81e-30	120.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG4251@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG4251@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1WXVG@135613|Chromatiales	135613|Chromatiales	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_4,Response_reg
k59_1722807_1	709032.Sulku_0608	1.43e-76	238.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,42SCV@68525|delta/epsilon subdivisions,2YPRK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar motor	motB	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
k59_1781297_1	1123517.JOMR01000001_gene1721	4.69e-128	375.0	COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,1RNKP@1236|Gammaproteobacteria,45ZWZ@72273|Thiotrichales	72273|Thiotrichales	O	PFAM Peptidase family M48	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
k59_1781297_2	870187.Thini_1279	1.57e-73	231.0	COG1893@1|root,COG1893@2|Bacteria,1R60C@1224|Proteobacteria,1RZQZ@1236|Gammaproteobacteria,460EC@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1023706_1	1565314.OA34_03185	6.42e-12	69.7	COG5000@1|root,COG5000@2|Bacteria,1NU7E@1224|Proteobacteria,43D06@68525|delta/epsilon subdivisions,2YTIH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	ABC transporter substrate binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,HATPase_c,PAS_4
k59_844141_1	511062.GU3_14675	7.71e-63	194.0	2BB53@1|root,324MI@2|Bacteria,1RM5X@1224|Proteobacteria,1SB2D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_844141_2	631362.Thi970DRAFT_02843	1.91e-09	58.9	COG3562@1|root,COG3562@2|Bacteria,1MUZT@1224|Proteobacteria,1RRSW@1236|Gammaproteobacteria,1WX45@135613|Chromatiales	135613|Chromatiales	M	PFAM Capsule polysaccharide biosynthesis	-	-	-	ko:K07265	-	-	-	-	ko00000	-	-	-	Capsule_synth
k59_1488714_1	709032.Sulku_0563	1.01e-84	258.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,42MDN@68525|delta/epsilon subdivisions,2YMPS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k59_1488714_2	1537917.JU82_03235	2.52e-116	339.0	COG2908@1|root,COG2908@2|Bacteria,1Q1QY@1224|Proteobacteria,42STS@68525|delta/epsilon subdivisions,2YP6A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	protein conserved in bacteria	lpxH	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos
k59_370696_1	709032.Sulku_1836	4.19e-143	413.0	COG0642@1|root,COG0642@2|Bacteria,1QZ2C@1224|Proteobacteria,42QBR@68525|delta/epsilon subdivisions,2YNQB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_2,sCache_2
k59_1023726_1	748247.AZKH_1926	1.7e-32	123.0	COG1053@1|root,COG1053@2|Bacteria,1MX5A@1224|Proteobacteria,2VN6P@28216|Betaproteobacteria,2KZIA@206389|Rhodocyclales	206389|Rhodocyclales	C	FAD dependent oxidoreductase	-	-	-	ko:K13796	-	-	-	-	ko00000	-	-	-	FAD_binding_2
k59_1023726_2	1007105.PT7_2323	8.3e-22	94.7	COG0583@1|root,COG0583@2|Bacteria,1MXR1@1224|Proteobacteria,2VKNP@28216|Betaproteobacteria,3T2HC@506|Alcaligenaceae	28216|Betaproteobacteria	K	LysR substrate binding domain	-	-	-	ko:K13794	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k59_370700_1	159087.Daro_2438	5.66e-175	498.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,2KUUN@206389|Rhodocyclales	206389|Rhodocyclales	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_608975_1	1123401.JHYQ01000005_gene179	7.29e-166	490.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,45ZTI@72273|Thiotrichales	72273|Thiotrichales	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_1844440_1	292415.Tbd_0893	6.99e-95	290.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,2VH1A@28216|Betaproteobacteria,1KRCI@119069|Hydrogenophilales	119069|Hydrogenophilales	J	tRNA synthetases class II (D, K and N)	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k59_844178_2	1537917.JU82_05680	2.93e-05	46.2	COG0500@1|root,COG2226@2|Bacteria,1NV27@1224|Proteobacteria,42P39@68525|delta/epsilon subdivisions,2YNRW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
k59_1371962_1	1537917.JU82_00990	2.41e-20	90.1	COG0778@1|root,COG0778@2|Bacteria,1Q0G9@1224|Proteobacteria,42MWR@68525|delta/epsilon subdivisions,2YNCN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	TIGRFAM SagB-type dehydrogenase domain	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_1371962_2	1249480.B649_06895	2.6e-43	151.0	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,42MSF@68525|delta/epsilon subdivisions,2YNA7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	alanine dehydrogenase	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
k59_1606376_1	1537917.JU82_05135	4.91e-123	362.0	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,42MBB@68525|delta/epsilon subdivisions,2YMFZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
k59_1025567_1	1249480.B649_09200	2.6e-71	223.0	COG0176@1|root,COG0176@2|Bacteria,1N9G3@1224|Proteobacteria,42MCK@68525|delta/epsilon subdivisions,2YMRY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
k59_1723958_1	159087.Daro_3763	7.96e-235	652.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,2VHYE@28216|Betaproteobacteria,2KV8R@206389|Rhodocyclales	206389|Rhodocyclales	E	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k59_1606384_2	709032.Sulku_1787	2.46e-120	346.0	COG0778@1|root,COG0778@2|Bacteria,1N95W@1224|Proteobacteria,42T85@68525|delta/epsilon subdivisions,2YPNS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_1606384_3	1249480.B649_10955	1.74e-34	120.0	COG1733@1|root,COG1733@2|Bacteria,1MZ6G@1224|Proteobacteria,42V7W@68525|delta/epsilon subdivisions,2YQAJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
k59_610412_1	709032.Sulku_1592	5.18e-08	53.1	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,42N3Z@68525|delta/epsilon subdivisions,2YMT4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
k59_610412_2	1249480.B649_04170	1.53e-110	320.0	COG0526@1|root,COG0526@2|Bacteria,1RKKW@1224|Proteobacteria,42SHJ@68525|delta/epsilon subdivisions,2YPQV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CO	Thioredoxin-like	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin,Thioredoxin,Thioredoxin_8
k59_94934_2	709032.Sulku_2256	5.02e-100	293.0	COG0179@1|root,COG0179@2|Bacteria,1MVFA@1224|Proteobacteria,42S7E@68525|delta/epsilon subdivisions,2YP7T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	2-keto-4-pentenoate hydratase	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
k59_1099581_1	498742.BSPA14S_0419	1.3e-27	112.0	COG2199@1|root,COG3706@2|Bacteria,2J7V5@203691|Spirochaetes	203691|Spirochaetes	T	response	rrp-1	-	-	ko:K18444	ko02020,map02020	M00662	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GGDEF,Hpt,Response_reg
k59_219265_1	709032.Sulku_0394	2.37e-74	243.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YMHP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3
k59_219265_2	1249480.B649_01825	1.03e-53	181.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2YMB5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	abc transporter atp-binding protein	yheS	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
k59_696042_1	411154.GFO_1789	2.88e-16	83.2	COG2244@1|root,COG2244@2|Bacteria,4NEVQ@976|Bacteroidetes,1HYFW@117743|Flavobacteriia	976|Bacteroidetes	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
k59_696050_1	159087.Daro_1989	7.27e-77	252.0	COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,2VHHQ@28216|Betaproteobacteria,2KU7T@206389|Rhodocyclales	206389|Rhodocyclales	Q	ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
k59_577437_1	425104.Ssed_2865	3.79e-93	310.0	COG0642@1|root,COG0834@1|root,COG5002@1|root,COG0642@2|Bacteria,COG0834@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,2QACP@267890|Shewanellaceae	1236|Gammaproteobacteria	T	histidine kinase A domain protein	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	CHASE,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,SBP_bac_3,dCache_1
k59_1331507_1	1249480.B649_02810	4.83e-115	337.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,42MDN@68525|delta/epsilon subdivisions,2YMPS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k59_1576293_1	1294143.H681_23520	7.5e-12	64.7	COG1585@1|root,COG1585@2|Bacteria,1N241@1224|Proteobacteria,1S5W4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	OU	Membrane protein implicated in regulation of membrane protease activity	ybbJ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07340	-	-	-	-	ko00000	-	-	-	NfeD
k59_162535_1	1249480.B649_02930	1.63e-65	212.0	COG2861@1|root,COG2861@2|Bacteria,1N3JP@1224|Proteobacteria,42RJN@68525|delta/epsilon subdivisions,2YP6V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Divergent polysaccharide deacetylase	-	-	-	ko:K09798	-	-	-	-	ko00000	-	-	-	Polysacc_deac_2
k59_219299_1	1121335.Clst_1721	1.12e-21	99.0	COG0840@1|root,COG0840@2|Bacteria,1UZ0J@1239|Firmicutes,24F2H@186801|Clostridia	186801|Clostridia	NT	Chemotaxis	pilJ	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
k59_1392510_1	264730.PSPPH_0282	2.61e-31	116.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,1RME5@1236|Gammaproteobacteria,1Z5VE@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	E	amino acid ABC transporter, ATP-binding protein	glnQ_2	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
k59_1392510_2	85643.Tmz1t_1342	3.72e-35	129.0	COG4266@1|root,COG4266@2|Bacteria,1MXJK@1224|Proteobacteria,2VKRI@28216|Betaproteobacteria,2KUB5@206389|Rhodocyclales	206389|Rhodocyclales	F	Belongs to the allantoicase family	alc	-	3.5.3.4	ko:K01477	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R02422	RC00379,RC00712	ko00000,ko00001,ko00002,ko01000	-	-	-	Allantoicase
k59_329235_1	1499967.BAYZ01000174_gene5832	1.76e-37	147.0	COG3437@1|root,COG4191@1|root,COG5000@1|root,COG3437@2|Bacteria,COG4191@2|Bacteria,COG5000@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	pleD	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464	2.7.7.65,4.6.1.1	ko:K01768,ko:K02488,ko:K17763	ko00230,ko02020,ko02025,ko04112,ko04113,ko04213,map00230,map02020,map02025,map04112,map04113,map04213	M00511,M00695	R00089,R00434,R08057	RC00295	ko00000,ko00001,ko00002,ko01000,ko02022,ko03021	-	-	-	GGDEF,HAMP,HATPase_c,HisKA,HisKA_3,PAS,PAS_4,PAS_9,Response_reg
k59_1099627_1	1123035.ARLA01000023_gene1132	1.56e-37	139.0	COG0715@1|root,COG0715@2|Bacteria,4PFJS@976|Bacteroidetes,1ID8Q@117743|Flavobacteriia,4C2S8@83612|Psychroflexus	976|Bacteroidetes	P	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
k59_696094_1	1562701.BBOF01000081_gene253	4.36e-108	321.0	28NGF@1|root,2Z9HT@2|Bacteria,1R9QF@1224|Proteobacteria,2VPSU@28216|Betaproteobacteria,1KD23@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_515144_1	1304883.KI912532_gene2121	1.01e-114	361.0	COG2911@1|root,COG2911@2|Bacteria,1QWGG@1224|Proteobacteria,2WGYX@28216|Betaproteobacteria,2KZX3@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
k59_1801449_1	159087.Daro_0339	8.45e-119	350.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,2VHQH@28216|Betaproteobacteria,2KVBF@206389|Rhodocyclales	206389|Rhodocyclales	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
k59_38483_1	1165841.SULAR_10549	5.56e-71	226.0	COG0475@1|root,COG0475@2|Bacteria,1RFKE@1224|Proteobacteria,43B2P@68525|delta/epsilon subdivisions,2YT5F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Sodium hydrogen exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
k59_1331562_1	1249480.B649_09795	2.78e-61	194.0	COG0745@1|root,COG0745@2|Bacteria,1N7TJ@1224|Proteobacteria,42SSI@68525|delta/epsilon subdivisions,2YPE6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_1331562_2	709032.Sulku_2075	6.8e-63	201.0	COG0642@1|root,COG0642@2|Bacteria,1QZ1Z@1224|Proteobacteria,42SN7@68525|delta/epsilon subdivisions,2YPK7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
k59_1684990_1	1304883.KI912532_gene3079	5.6e-97	286.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,2VIME@28216|Betaproteobacteria,2KUY1@206389|Rhodocyclales	206389|Rhodocyclales	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
k59_1685003_1	641107.CDLVIII_0710	9.24e-71	241.0	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,2490U@186801|Clostridia,36EG3@31979|Clostridiaceae	186801|Clostridia	Q	TIGRFAM amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,NAD_binding_4,PP-binding,Thioesterase
k59_1801492_1	159087.Daro_2176	3.84e-98	299.0	COG3517@1|root,COG3517@2|Bacteria,1MU5C@1224|Proteobacteria,2VKCP@28216|Betaproteobacteria,2KUA6@206389|Rhodocyclales	206389|Rhodocyclales	S	This family consists of a number of uncharacterised bacterial proteins. The function of this family is	-	-	-	ko:K11900	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	VipB
k59_275035_1	1045856.EcWSU1_00560	9.76e-07	53.5	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,3X10Q@547|Enterobacter	1236|Gammaproteobacteria	NT	chemotaxis	tsr	GO:0001101,GO:0001932,GO:0003674,GO:0004888,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006928,GO:0006935,GO:0007154,GO:0007165,GO:0007172,GO:0008104,GO:0008150,GO:0009593,GO:0009605,GO:0009719,GO:0009966,GO:0009987,GO:0010033,GO:0010243,GO:0010646,GO:0016020,GO:0016021,GO:0016043,GO:0019220,GO:0019222,GO:0019899,GO:0019900,GO:0019901,GO:0022607,GO:0023051,GO:0023052,GO:0031224,GO:0031226,GO:0031323,GO:0031399,GO:0032101,GO:0032110,GO:0032268,GO:0032879,GO:0032991,GO:0033036,GO:0034613,GO:0034622,GO:0038023,GO:0040011,GO:0040012,GO:0042221,GO:0042325,GO:0042330,GO:0042802,GO:0042803,GO:0043113,GO:0043200,GO:0043424,GO:0043549,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045859,GO:0046983,GO:0048583,GO:0048870,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0050920,GO:0051171,GO:0051174,GO:0051179,GO:0051246,GO:0051259,GO:0051260,GO:0051270,GO:0051338,GO:0051606,GO:0051641,GO:0051668,GO:0051674,GO:0051716,GO:0060089,GO:0060255,GO:0065003,GO:0065007,GO:0065009,GO:0070727,GO:0070887,GO:0071229,GO:0071230,GO:0071310,GO:0071417,GO:0071495,GO:0071840,GO:0071944,GO:0072657,GO:0080090,GO:0098561,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902021,GO:2000145	-	ko:K03406,ko:K05874,ko:K05875,ko:K05876,ko:K05877	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,TarH
k59_1627877_1	709032.Sulku_1616	1.51e-75	239.0	COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,42MQ6@68525|delta/epsilon subdivisions,2YNPN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DNA photolyase family	phrB	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
k59_1162653_1	1249480.B649_04820	1.42e-109	326.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,42NM8@68525|delta/epsilon subdivisions,2YNFK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
k59_162642_1	90814.KL370891_gene113	6.29e-85	259.0	COG0730@1|root,COG0730@2|Bacteria,1MVBS@1224|Proteobacteria,1S62V@1236|Gammaproteobacteria,463IN@72273|Thiotrichales	72273|Thiotrichales	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k59_162642_2	1499499.EV06_1811	1.4e-05	45.1	COG0268@1|root,COG0268@2|Bacteria,1G7PV@1117|Cyanobacteria,1MN31@1212|Prochloraceae	1117|Cyanobacteria	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
k59_737532_1	640081.Dsui_0417	1.11e-131	389.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2VH8Z@28216|Betaproteobacteria,2KZRQ@206389|Rhodocyclales	206389|Rhodocyclales	H	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
k59_862059_1	1297570.MESS4_340114	8.92e-07	50.8	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,2TRZZ@28211|Alphaproteobacteria,43I3N@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	H	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
k59_862059_2	1415754.JQMK01000002_gene2508	1.71e-49	170.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,1RM7N@1236|Gammaproteobacteria,463YV@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	Glutamate-1-semialdehyde aminotransferase	hemL	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016853,GO:0016866,GO:0016869,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042286,GO:0042440,GO:0042802,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iUMNK88_1353.UMNK88_158	Aminotran_3
k59_1801553_1	563040.Saut_0094	1.56e-63	213.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,42PIU@68525|delta/epsilon subdivisions,2YNAZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_1216046_1	1249480.B649_06445	2.98e-45	166.0	COG3290@1|root,COG3614@1|root,COG4191@1|root,COG3290@2|Bacteria,COG3614@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42R1U@68525|delta/epsilon subdivisions,2YNX6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,PAS_9
k59_1162715_1	1537917.JU82_03870	1.53e-31	112.0	COG0636@1|root,COG0636@2|Bacteria,1NAIE@1224|Proteobacteria,42VAI@68525|delta/epsilon subdivisions,2YPYI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
k59_1162715_2	1537917.JU82_03865	1.96e-256	720.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,42MTZ@68525|delta/epsilon subdivisions,2YMPF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
k59_451997_1	1165841.SULAR_01345	9.77e-97	306.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,42M4I@68525|delta/epsilon subdivisions,2YMFT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_1801622_1	709032.Sulku_1960	1.61e-92	301.0	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG5000@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,COG5000@2|Bacteria,1RGKE@1224|Proteobacteria	1224|Proteobacteria	T	GAF domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,GAF,GAF_2,HATPase_c,HisKA,HisKA_2,HisKA_3,PAS,PAS_3,PAS_4,PAS_9,Pkinase,STAS,SpoIIE
k59_1576562_1	1537917.JU82_03570	4.3e-84	252.0	COG1192@1|root,COG1192@2|Bacteria,1NGVZ@1224|Proteobacteria,42VBJ@68525|delta/epsilon subdivisions	1224|Proteobacteria	D	Involved in chromosome partitioning	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	-
k59_808335_1	1132855.KB913035_gene573	1.27e-34	123.0	COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,2VQ10@28216|Betaproteobacteria,2KMN9@206350|Nitrosomonadales	206350|Nitrosomonadales	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
k59_808335_2	583345.Mmol_2068	2.25e-58	182.0	COG1539@1|root,COG1539@2|Bacteria,1MZ8Z@1224|Proteobacteria,2VUVV@28216|Betaproteobacteria,2KMXM@206350|Nitrosomonadales	206350|Nitrosomonadales	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	-	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
k59_633290_1	159087.Daro_0269	4.15e-158	452.0	COG0454@1|root,COG0456@2|Bacteria,1R8GF@1224|Proteobacteria,2VNUV@28216|Betaproteobacteria	28216|Betaproteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,PilZ
k59_452030_1	1537917.JU82_09350	7.51e-120	353.0	COG0840@1|root,COG0840@2|Bacteria,1R5W9@1224|Proteobacteria,42PPM@68525|delta/epsilon subdivisions,2YN9B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	methyl-accepting chemotaxis protein	tlpD	-	-	-	-	-	-	-	-	-	-	-	CZB,MCPsignal
k59_1801645_1	159087.Daro_1034	3.23e-71	219.0	COG2761@1|root,COG2761@2|Bacteria,1NXUB@1224|Proteobacteria,2VNUN@28216|Betaproteobacteria,2KWSZ@206389|Rhodocyclales	206389|Rhodocyclales	Q	DSBA Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
k59_862152_1	1165841.SULAR_10389	5.03e-30	109.0	COG0080@1|root,COG0080@2|Bacteria,1RA2M@1224|Proteobacteria,42RE7@68525|delta/epsilon subdivisions,2YNWY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
k59_862152_2	1165841.SULAR_10384	4.7e-132	378.0	COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,42MZP@68525|delta/epsilon subdivisions,2YMN7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
k59_1282472_1	306264.CUP0215	6.85e-68	221.0	COG0579@1|root,COG0579@2|Bacteria,1MUCC@1224|Proteobacteria,42M2Q@68525|delta/epsilon subdivisions,2YMYG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Malate quinone- oxidoreductase	mqo	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.1.5.4	ko:K00116	ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00009,M00011	R00360,R00361,R01257	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0086	Mqo
k59_577679_2	1167006.UWK_01462	7.2e-122	355.0	COG2084@1|root,COG2084@2|Bacteria,1PHRJ@1224|Proteobacteria,4348T@68525|delta/epsilon subdivisions,2X9TJ@28221|Deltaproteobacteria,2MNX7@213118|Desulfobacterales	28221|Deltaproteobacteria	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
k59_1392721_1	387093.SUN_1362	1.29e-103	310.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MKR@68525|delta/epsilon subdivisions,2YN1A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Aminotransferase	aspB	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_577680_2	1249480.B649_02125	6.59e-120	357.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,42NIH@68525|delta/epsilon subdivisions,2YMVT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	FP	Guanosine pentaphosphate phosphohydrolase	gppA	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
k59_329492_1	1249480.B649_07200	1.87e-127	369.0	COG2301@1|root,COG2301@2|Bacteria,1NUDQ@1224|Proteobacteria,42QUW@68525|delta/epsilon subdivisions,2YNZV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the HpcH HpaI aldolase family	citE	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
k59_1049925_1	198628.Dda3937_02500	5.13e-49	165.0	COG1876@1|root,COG1876@2|Bacteria,1N2IC@1224|Proteobacteria,1S0DU@1236|Gammaproteobacteria,2JCRJ@204037|Dickeya	1236|Gammaproteobacteria	M	PFAM peptidase M15B and M15C DD-carboxypeptidase VanY endolysin	vanY	-	-	-	-	-	-	-	-	-	-	-	VanY
k59_38717_1	760154.Sulba_0654	2.24e-90	287.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,42MTZ@68525|delta/epsilon subdivisions,2YMPF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
k59_1628057_1	298386.PBPRB1444	4.53e-06	50.4	COG1100@1|root,COG1100@2|Bacteria,1N5QS@1224|Proteobacteria,1RRJ1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_24
k59_1331841_1	709032.Sulku_1926	5.43e-133	386.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2YMC1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_1099883_1	1249480.B649_01750	1.75e-87	268.0	COG0784@1|root,COG0784@2|Bacteria,1Q9XN@1224|Proteobacteria,42YUB@68525|delta/epsilon subdivisions,2YRFD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_808416_1	265072.Mfla_1760	1.13e-81	269.0	COG0835@1|root,COG0835@2|Bacteria,1QVCF@1224|Proteobacteria,2VK5W@28216|Betaproteobacteria,2KKVY@206350|Nitrosomonadales	206350|Nitrosomonadales	NT	Two component signalling adaptor domain	-	-	-	-	-	-	-	-	-	-	-	-	CheW
k59_219591_1	765952.PUV_25190	0.0004	49.3	COG1538@1|root,COG1538@2|Bacteria,2JGS2@204428|Chlamydiae	204428|Chlamydiae	MU	Outer membrane efflux protein	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
k59_1868413_1	1123517.JOMR01000001_gene260	2.58e-58	201.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,45ZQ4@72273|Thiotrichales	72273|Thiotrichales	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
k59_737680_1	1249480.B649_05035	2.74e-25	99.0	COG1521@1|root,COG1521@2|Bacteria,1PZXA@1224|Proteobacteria,42RA8@68525|delta/epsilon subdivisions,2YP14@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
k59_275294_1	326298.Suden_1054	1.63e-102	303.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,42MD3@68525|delta/epsilon subdivisions,2YMMW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Oxidoreductase	oorB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
k59_1685244_1	709032.Sulku_2514	2e-171	492.0	COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,42MYF@68525|delta/epsilon subdivisions,2YMXD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Single-stranded-DNA-specific exonuclease (RecJ)	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
k59_1628097_1	159087.Daro_3292	9e-53	171.0	2CDCV@1|root,308Y1@2|Bacteria,1N74F@1224|Proteobacteria,2VSMP@28216|Betaproteobacteria,2KWQ8@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1628097_2	1304883.KI912532_gene3243	9.71e-51	163.0	COG1051@1|root,COG1051@2|Bacteria,1N03W@1224|Proteobacteria,2VRC0@28216|Betaproteobacteria,2KWI7@206389|Rhodocyclales	206389|Rhodocyclales	F	Belongs to the Nudix hydrolase family. NudJ subfamily	nudJ	-	-	-	-	-	-	-	-	-	-	-	NUDIX
k59_1216209_1	395494.Galf_2814	1.07e-94	290.0	COG1696@1|root,COG1696@2|Bacteria,1MUXN@1224|Proteobacteria,2VISD@28216|Betaproteobacteria,44VAU@713636|Nitrosomonadales	28216|Betaproteobacteria	M	PFAM membrane bound O-acyl transferase MBOAT family protein	pacA	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
k59_633402_1	159087.Daro_3006	1.55e-82	273.0	COG0517@1|root,COG0642@1|root,COG0784@1|root,COG2198@1|root,COG2202@1|root,COG2203@1|root,COG0517@2|Bacteria,COG0642@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,1NC9X@1224|Proteobacteria,2WGIN@28216|Betaproteobacteria,2KZWQ@206389|Rhodocyclales	206389|Rhodocyclales	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	CBS,GAF_2,HATPase_c,HisKA,Hpt,PAS_3,Response_reg
k59_1049996_1	1123401.JHYQ01000012_gene2827	4.85e-10	60.1	COG0594@1|root,COG0594@2|Bacteria,1MZQE@1224|Proteobacteria,1S90M@1236|Gammaproteobacteria,4630Y@72273|Thiotrichales	72273|Thiotrichales	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
k59_1049996_2	396588.Tgr7_3318	4.19e-08	58.9	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,1RMH1@1236|Gammaproteobacteria,1WWKE@135613|Chromatiales	135613|Chromatiales	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
k59_1458384_1	1305836.AXVE01000006_gene429	2.74e-22	100.0	2DBIB@1|root,2Z9FB@2|Bacteria,1UZJY@1239|Firmicutes,4IRFR@91061|Bacilli,26EQ0@186818|Planococcaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_392795_2	748247.AZKH_p0005	1.76e-09	55.8	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,2VV67@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
k59_1630956_1	1121035.AUCH01000021_gene2730	2.22e-58	205.0	COG0835@1|root,COG0835@2|Bacteria,1QVCF@1224|Proteobacteria,2VK5W@28216|Betaproteobacteria,2KVUN@206389|Rhodocyclales	206389|Rhodocyclales	NT	Two component signalling adaptor domain	-	-	-	-	-	-	-	-	-	-	-	-	CheW
k59_1749480_2	887062.HGR_09099	4.12e-05	43.9	COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,2VUC6@28216|Betaproteobacteria,4AEBZ@80864|Comamonadaceae	28216|Betaproteobacteria	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
k59_1461054_1	1123517.JOMR01000001_gene482	2.38e-87	268.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,1RN8M@1236|Gammaproteobacteria,45ZU5@72273|Thiotrichales	72273|Thiotrichales	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
k59_1579916_2	1249480.B649_03235	2.42e-35	124.0	COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,42RMF@68525|delta/epsilon subdivisions,2YPMK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	pgpA	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
k59_332619_1	709032.Sulku_2380	2.58e-99	293.0	COG1861@1|root,COG1861@2|Bacteria,1RG42@1224|Proteobacteria,42SUK@68525|delta/epsilon subdivisions,2YRW4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Cytidylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_3
k59_332619_2	709032.Sulku_2381	1.85e-21	90.1	COG0535@1|root,COG0535@2|Bacteria,1PEYS@1224|Proteobacteria,42SNS@68525|delta/epsilon subdivisions,2YQGZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
k59_581044_1	159087.Daro_3546	1.57e-63	196.0	COG0664@1|root,COG0664@2|Bacteria,1N6WV@1224|Proteobacteria,2VWSV@28216|Betaproteobacteria,2KZBU@206389|Rhodocyclales	206389|Rhodocyclales	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
k59_278717_1	1504981.KO116_0354	3.06e-18	78.6	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,1S9NV@1236|Gammaproteobacteria,1XKES@135619|Oceanospirillales	135619|Oceanospirillales	U	Preprotein translocase subunit YajC	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
k59_278717_2	159087.Daro_3280	3.19e-56	191.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,2VHKD@28216|Betaproteobacteria,2KV11@206389|Rhodocyclales	206389|Rhodocyclales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD-TM1,SecD_SecF,Sec_GG
k59_1219181_1	709032.Sulku_1216	1.92e-50	167.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02246,ko:K02247,ko:K02456,ko:K02457,ko:K02458,ko:K10924	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
k59_1579965_1	709032.Sulku_0661	1.63e-104	325.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,42MN5@68525|delta/epsilon subdivisions,2YN0Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	DUF294,GlnD_UR_UTase,HD,NTP_transf_2
k59_392877_1	700598.Niako_2302	4.68e-56	196.0	COG3383@1|root,COG3383@2|Bacteria,4PKV4@976|Bacteroidetes,1IX2V@117747|Sphingobacteriia	976|Bacteroidetes	C	TIGRFAM formate dehydrogenase, alpha subunit, archaeal-type	hndD	-	1.12.1.3,1.17.1.9	ko:K00123,ko:K18332	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
k59_1871114_1	563040.Saut_1116	3.02e-45	156.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,42M5K@68525|delta/epsilon subdivisions,2YMJ2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
k59_1871114_2	326298.Suden_1051	1.16e-185	518.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,42M2W@68525|delta/epsilon subdivisions,2YMZR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
k59_1631055_1	325777.GW15_0203195	3.49e-34	135.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,1X50J@135614|Xanthomonadales	135614|Xanthomonadales	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_1461143_1	1249480.B649_06240	4.34e-64	197.0	COG1959@1|root,COG1959@2|Bacteria,1PC6Q@1224|Proteobacteria,42VG6@68525|delta/epsilon subdivisions,2YQBX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
k59_1461143_2	1026882.MAMP_02749	1.5e-05	49.3	COG3448@1|root,COG3448@2|Bacteria,1MXJG@1224|Proteobacteria,1RYFC@1236|Gammaproteobacteria,460S7@72273|Thiotrichales	72273|Thiotrichales	T	HPP family	-	-	-	-	-	-	-	-	-	-	-	-	HPP
k59_1285069_1	929558.SMGD1_0378	1.91e-49	178.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2YMB9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	chemotaxis protein	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
k59_1631081_1	709032.Sulku_2542	2.74e-152	449.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2YN94@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
k59_242890_2	317025.Tcr_0614	4.37e-118	345.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,1RNME@1236|Gammaproteobacteria,46025@72273|Thiotrichales	72273|Thiotrichales	G	Inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
k59_242890_3	317025.Tcr_0615	3.04e-27	107.0	COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,1RPD3@1236|Gammaproteobacteria,460FF@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	-	2.1.1.200	ko:K02533,ko:K15396	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
k59_1769195_1	1304883.KI912532_gene1826	4.73e-160	463.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2VHVH@28216|Betaproteobacteria,2KUHI@206389|Rhodocyclales	206389|Rhodocyclales	G	PQQ-like domain	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ
k59_1357773_1	1165841.SULAR_07810	1.34e-28	112.0	COG0457@1|root,COG0457@2|Bacteria,1NR72@1224|Proteobacteria	1224|Proteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1357773_2	1165841.SULAR_07815	2.17e-88	264.0	COG0810@1|root,COG0810@2|Bacteria,1NDQZ@1224|Proteobacteria,42VIY@68525|delta/epsilon subdivisions	1224|Proteobacteria	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	tonB2	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
k59_1710532_1	159087.Daro_2727	1.08e-83	269.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,2VHYF@28216|Betaproteobacteria,2KVIZ@206389|Rhodocyclales	206389|Rhodocyclales	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_1651989_1	1537917.JU82_02635	2.17e-93	275.0	COG0807@1|root,COG0807@2|Bacteria,1MWZR@1224|Proteobacteria,42N2Q@68525|delta/epsilon subdivisions,2YM8K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate	ribA	-	3.5.4.25	ko:K01497	ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024	M00125	R00425	RC00293,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydro2
k59_1299229_1	159087.Daro_1465	4.24e-95	282.0	COG3346@1|root,COG3346@2|Bacteria,1MZUH@1224|Proteobacteria,2VSAZ@28216|Betaproteobacteria,2KWKA@206389|Rhodocyclales	206389|Rhodocyclales	S	SURF1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	SURF1
k59_1299229_2	159087.Daro_1464	3.61e-50	166.0	COG1999@1|root,COG1999@2|Bacteria,1N6R6@1224|Proteobacteria,2VXI0@28216|Betaproteobacteria,2KZS1@206389|Rhodocyclales	206389|Rhodocyclales	S	signal sequence binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_655518_1	1163407.UU7_15730	7.7e-34	122.0	COG0500@1|root,COG0500@2|Bacteria,1RDHE@1224|Proteobacteria,1S3U0@1236|Gammaproteobacteria,1X6QC@135614|Xanthomonadales	135614|Xanthomonadales	Q	Protein of unknown function (DUF938)	-	-	-	-	-	-	-	-	-	-	-	-	DUF938
k59_1417689_1	709032.Sulku_1952	3.08e-79	254.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42UQ6@68525|delta/epsilon subdivisions,2YQ4D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	PAS fold	-	-	-	ko:K03776	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	PAS_3
k59_595503_1	1537917.JU82_10775	6.79e-29	117.0	COG0745@1|root,COG0745@2|Bacteria,1QXJT@1224|Proteobacteria,42V47@68525|delta/epsilon subdivisions,2YQ8S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	RESPONSE REGULATOR receiver	-	-	-	ko:K07288	-	-	-	-	ko00000	-	-	-	-
k59_1299247_1	1537917.JU82_01170	2.81e-70	215.0	2AIU4@1|root,319B6@2|Bacteria,1Q28N@1224|Proteobacteria,42V6E@68525|delta/epsilon subdivisions,2YQ6D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1299247_2	1249480.B649_05665	1.2e-35	127.0	COG3852@1|root,COG3852@2|Bacteria,1QAGK@1224|Proteobacteria,42RSW@68525|delta/epsilon subdivisions,2YPDC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_242935_1	387093.SUN_0223	5.26e-19	87.8	COG1426@1|root,COG1426@2|Bacteria	2|Bacteria	S	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_538280_1	1537917.JU82_09720	1.31e-120	350.0	COG3301@1|root,COG3301@2|Bacteria,1QSRQ@1224|Proteobacteria,42PAY@68525|delta/epsilon subdivisions,2YN5Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
k59_770341_1	159087.Daro_0061	3.41e-100	308.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VHGH@28216|Betaproteobacteria,2KUY0@206389|Rhodocyclales	206389|Rhodocyclales	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	yheS	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
k59_183296_1	1537917.JU82_04385	7.68e-124	363.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,42M7K@68525|delta/epsilon subdivisions,2YMZY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
k59_418984_2	159087.Daro_0871	1.91e-46	155.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,2VI78@28216|Betaproteobacteria,2KV5S@206389|Rhodocyclales	206389|Rhodocyclales	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
k59_242962_1	1123054.KB907706_gene2264	1.81e-33	132.0	COG1283@1|root,COG1283@2|Bacteria,1MUDE@1224|Proteobacteria,1RNMM@1236|Gammaproteobacteria,1WXUR@135613|Chromatiales	135613|Chromatiales	P	PFAM Na Picotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
k59_1710593_1	261292.Nit79A3_0829	4.68e-31	109.0	COG0291@1|root,COG0291@2|Bacteria,1N6V4@1224|Proteobacteria,2VVS9@28216|Betaproteobacteria,373NU@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
k59_1710593_2	395494.Galf_1113	4.93e-67	204.0	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,2VRWF@28216|Betaproteobacteria,44VWN@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
k59_1417733_1	90813.JQMT01000001_gene2096	2.66e-39	143.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,1RNHP@1236|Gammaproteobacteria,45ZN6@72273|Thiotrichales	72273|Thiotrichales	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
k59_1417733_2	95619.PM1_0228995	3.22e-13	70.9	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,1RMNP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	GO:0003674,GO:0003824,GO:0003887,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0022616,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
k59_1242632_1	1249480.B649_07350	1.43e-145	420.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,42M3C@68525|delta/epsilon subdivisions,2YMHJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
k59_242971_1	1249480.B649_02825	2.99e-32	131.0	COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2YMB9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	chemotaxis protein	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k59_1710600_2	426114.THI_1806	1.41e-85	260.0	28KDQ@1|root,2ZA05@2|Bacteria,1QVCG@1224|Proteobacteria,2VTD9@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_888882_1	1537917.JU82_08515	7.8e-202	574.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,43BJ8@68525|delta/epsilon subdivisions,2YMMJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	penicillin-binding protein	pbpA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
k59_419013_1	709032.Sulku_0958	8.1e-132	382.0	COG1306@1|root,COG1306@2|Bacteria,1MWBY@1224|Proteobacteria,42NSR@68525|delta/epsilon subdivisions,2YP0V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Putative glycosyl hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4015
k59_1476156_1	159087.Daro_3837	1.04e-67	212.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,2VI91@28216|Betaproteobacteria,2KUT2@206389|Rhodocyclales	206389|Rhodocyclales	K	RNA polymerase sigma	rpoH	-	-	ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r4
k59_1124638_1	640081.Dsui_2681	9.91e-73	229.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,2VIBP@28216|Betaproteobacteria,2KUHP@206389|Rhodocyclales	206389|Rhodocyclales	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
k59_1124638_2	1304883.KI912532_gene2596	4.8e-70	217.0	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,2VHDG@28216|Betaproteobacteria,2KV6X@206389|Rhodocyclales	206389|Rhodocyclales	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
k59_1593417_1	1249480.B649_11255	3.81e-81	258.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,42MEI@68525|delta/epsilon subdivisions,2YN3Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Asparagine synthase, glutamine-hydrolyzing	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_595576_1	709032.Sulku_2439	6.53e-67	213.0	2AIAA@1|root,318R4@2|Bacteria,1Q0T4@1224|Proteobacteria,42SFV@68525|delta/epsilon subdivisions,2YPR6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	1.13.11.63	ko:K21817	-	-	-	-	ko00000,ko01000	-	-	-	-
k59_1829606_1	159087.Daro_3353	1.32e-116	338.0	COG3672@1|root,COG3672@2|Bacteria,1RDQS@1224|Proteobacteria,2VR6A@28216|Betaproteobacteria,2KWI6@206389|Rhodocyclales	206389|Rhodocyclales	S	Bacterial transglutaminase-like cysteine proteinase BTLCP	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C93
k59_66057_1	709032.Sulku_0472	3.77e-85	266.0	COG2199@1|root,COG3829@1|root,COG3706@2|Bacteria,COG3829@2|Bacteria,1NAG0@1224|Proteobacteria,42T7C@68525|delta/epsilon subdivisions,2YR5V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_9
k59_300586_1	1249480.B649_10895	1.26e-112	327.0	COG0602@1|root,COG0602@2|Bacteria,1PDNI@1224|Proteobacteria,42R24@68525|delta/epsilon subdivisions,2YN2N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_12,Fer4_14
k59_770402_1	1537917.JU82_00190	1.58e-65	207.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,42P1N@68525|delta/epsilon subdivisions,2YTRU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
k59_770402_2	709032.Sulku_1952	3.07e-135	404.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42UQ6@68525|delta/epsilon subdivisions,2YQ4D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	PAS fold	-	-	-	ko:K03776	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	PAS_3
k59_183366_1	580332.Slit_0662	2.84e-64	206.0	COG1902@1|root,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,2VHDY@28216|Betaproteobacteria,44VQV@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	1.3.1.34	ko:K00219	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_FMN
k59_183366_2	159087.Daro_0360	3.89e-40	132.0	COG1942@1|root,COG1942@2|Bacteria,1N6WW@1224|Proteobacteria,2VWV3@28216|Betaproteobacteria,2KXBJ@206389|Rhodocyclales	206389|Rhodocyclales	S	Tautomerase enzyme	-	-	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase
k59_66064_1	1249480.B649_06520	1.49e-121	371.0	COG2199@1|root,COG4191@1|root,COG3706@2|Bacteria,COG4191@2|Bacteria,1QYD2@1224|Proteobacteria,42PVI@68525|delta/epsilon subdivisions,2YNV3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_3,PAS_9
k59_538386_2	1192124.LIG30_1195	4.03e-78	234.0	COG0394@1|root,COG0394@2|Bacteria,1MWYQ@1224|Proteobacteria,2VPZB@28216|Betaproteobacteria,1JZRG@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Low molecular weight phosphotyrosine protein phosphatase	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
k59_655638_2	1249480.B649_09015	8.18e-51	163.0	2AK8C@1|root,31AYM@2|Bacteria,1Q6J3@1224|Proteobacteria,43398@68525|delta/epsilon subdivisions,2YSRM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_655638_3	1537917.JU82_03470	1.97e-64	197.0	28QM5@1|root,319KE@2|Bacteria,1Q3DZ@1224|Proteobacteria,42X5X@68525|delta/epsilon subdivisions,2YQT9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
k59_655638_4	97096.XP_007789949.1	2.94e-11	60.5	COG3323@1|root,2S6WE@2759|Eukaryota,3A4TP@33154|Opisthokonta,3P44F@4751|Fungi,3QWB9@4890|Ascomycota,21AR2@147550|Sordariomycetes	4751|Fungi	S	Structural toxin protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_595614_1	573061.Clocel_2482	4.17e-63	218.0	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,2490U@186801|Clostridia,36EG3@31979|Clostridiaceae	186801|Clostridia	Q	TIGRFAM amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_420980_1	1165841.SULAR_07680	4.25e-59	197.0	COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,42N9J@68525|delta/epsilon subdivisions,2YMC3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Long-chain fatty acid transport protein	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k59_185322_1	387093.SUN_0412	6.62e-84	254.0	COG2009@1|root,2ZBTX@2|Bacteria,1RB22@1224|Proteobacteria,42NAY@68525|delta/epsilon subdivisions,2YMAV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	fumarate reductase	frdC	-	-	ko:K00246	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
k59_712623_1	1537917.JU82_00480	2.13e-130	373.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,42M44@68525|delta/epsilon subdivisions,2YMH6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth,NMO
k59_1712676_2	221988.MS0658	1.05e-64	201.0	COG0615@1|root,COG0615@2|Bacteria,1RAJP@1224|Proteobacteria,1S65A@1236|Gammaproteobacteria,1Y9MD@135625|Pasteurellales	135625|Pasteurellales	IM	Cytidylyltransferase-like	-	-	2.7.7.39	ko:K00980	ko00564,map00564	-	R00856	RC00002	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like
k59_1712676_3	1537915.JU57_06695	1.78e-13	69.7	COG0318@1|root,COG0318@2|Bacteria,1R3S7@1224|Proteobacteria,42PB1@68525|delta/epsilon subdivisions,2YN6Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
k59_1245042_1	709032.Sulku_0009	6.05e-88	273.0	COG0617@1|root,COG1418@1|root,COG0617@2|Bacteria,COG1418@2|Bacteria,1MU2X@1224|Proteobacteria,42MJJ@68525|delta/epsilon subdivisions,2YMGU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	tRNA nucleotidyltransferase poly(A) polymerase	cca	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
k59_597831_1	485913.Krac_7657	1.85e-08	58.9	COG0477@1|root,COG0477@2|Bacteria,2GA6R@200795|Chloroflexi	200795|Chloroflexi	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
k59_597831_2	748247.AZKH_1928	1.33e-38	138.0	COG0111@1|root,COG0111@2|Bacteria,1MW0R@1224|Proteobacteria,2VHIZ@28216|Betaproteobacteria	28216|Betaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
k59_1831952_1	439235.Dalk_4886	2.34e-06	55.8	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,42QB7@68525|delta/epsilon subdivisions,2WM6Y@28221|Deltaproteobacteria,2MHYS@213118|Desulfobacterales	28221|Deltaproteobacteria	T	metal-dependent phosphohydrolase HD region	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
k59_1831952_2	159087.Daro_1454	1.7e-16	77.8	COG0535@1|root,COG1433@1|root,COG0535@2|Bacteria,COG1433@2|Bacteria,1MWDC@1224|Proteobacteria,2VJBQ@28216|Betaproteobacteria,2KV00@206389|Rhodocyclales	206389|Rhodocyclales	C	Dinitrogenase iron-molybdenum cofactor	-	-	-	ko:K02585	-	-	-	-	ko00000	-	-	-	Nitro_FeMo-Co,Radical_SAM
k59_128886_1	1121035.AUCH01000004_gene403	2.88e-97	306.0	COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,2VJ9A@28216|Betaproteobacteria,2KV3Z@206389|Rhodocyclales	206389|Rhodocyclales	C	UPF0313 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
k59_245308_1	1249480.B649_00345	5.73e-37	127.0	2ANKR@1|root,31DJY@2|Bacteria,1QAVT@1224|Proteobacteria,42VKM@68525|delta/epsilon subdivisions,2YQB6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_245308_2	1537917.JU82_00650	1.34e-69	222.0	COG1293@1|root,COG1293@2|Bacteria,1R54S@1224|Proteobacteria,42MYG@68525|delta/epsilon subdivisions,2YT8X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	RNA-binding protein homologous to eukaryotic snRNP	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
k59_128889_1	709032.Sulku_0230	5.33e-158	447.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42MKX@68525|delta/epsilon subdivisions,2YMGF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
k59_128889_2	709032.Sulku_0229	7.18e-20	87.4	COG0330@1|root,COG0330@2|Bacteria,1N5JY@1224|Proteobacteria,42MNX@68525|delta/epsilon subdivisions,2YME9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	COG0330 Membrane protease subunits stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_1595454_1	62977.ACIAD0822	5.9e-61	204.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,1RP7U@1236|Gammaproteobacteria,3NIRM@468|Moraxellaceae	1236|Gammaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
k59_1712703_1	1249480.B649_05980	2.37e-69	229.0	COG2319@1|root,COG2319@2|Bacteria,1Q4XR@1224|Proteobacteria,42PRP@68525|delta/epsilon subdivisions,2YMZB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	WD40
k59_421022_1	709032.Sulku_2474	6.56e-110	326.0	29Y2F@1|root,30JVD@2|Bacteria,1RAWX@1224|Proteobacteria,4300B@68525|delta/epsilon subdivisions,2YRWY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1771445_1	1537917.JU82_04875	8.77e-158	449.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,42M54@68525|delta/epsilon subdivisions,2YNPD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	COG0436 Aspartate tyrosine aromatic aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
k59_1245084_1	404380.Gbem_4009	3.75e-15	76.6	COG2703@1|root,COG2703@2|Bacteria,1RI40@1224|Proteobacteria	1224|Proteobacteria	P	Oxygen-binding protein. May be involved in a storage mechanism or for delivery to oxygen-requiring enzymes. The oxygen- binding site contains two iron atoms	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
k59_421023_1	1249480.B649_06585	5.24e-40	139.0	COG0454@1|root,COG0456@2|Bacteria,1Q9FS@1224|Proteobacteria,42YQT@68525|delta/epsilon subdivisions,2YRH5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
k59_421023_3	1537917.JU82_05400	9.97e-28	101.0	2EJKX@1|root,33DBU@2|Bacteria,1NMQF@1224|Proteobacteria,42WWP@68525|delta/epsilon subdivisions,2YQW8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Rop-like	-	-	-	-	-	-	-	-	-	-	-	-	Rop-like
k59_950873_2	68194.JNXR01000004_gene4498	4.64e-25	105.0	COG1012@1|root,COG1012@2|Bacteria,2GT45@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	pcd	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_1831984_2	1123236.KB899387_gene1946	2.15e-24	105.0	COG3106@1|root,COG3106@2|Bacteria,1MX6E@1224|Proteobacteria,1RQ05@1236|Gammaproteobacteria,464CF@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	YcjX-like family, DUF463	ycjX	-	-	ko:K06918	-	-	-	-	ko00000	-	-	-	DUF463
k59_772358_1	1304883.KI912532_gene1121	1.88e-104	313.0	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,2VH1E@28216|Betaproteobacteria,2KUQS@206389|Rhodocyclales	206389|Rhodocyclales	F	COG0044 Dihydroorotase and related cyclic amidohydrolases	pyrX	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
k59_540787_1	709032.Sulku_2231	3.34e-26	99.8	COG4969@1|root,COG4969@2|Bacteria,1QZMZ@1224|Proteobacteria,42U5N@68525|delta/epsilon subdivisions,2YPXN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
k59_540787_2	709032.Sulku_2190	2.42e-74	236.0	COG1866@1|root,COG1866@2|Bacteria,1MWXN@1224|Proteobacteria,42N5Y@68525|delta/epsilon subdivisions,2YN1U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
k59_1009791_1	387093.SUN_0132	4.84e-112	357.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2YMP9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5,RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_1127158_1	1537917.JU82_09550	6.78e-138	393.0	COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,42N5W@68525|delta/epsilon subdivisions,2YN05@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
k59_1420329_1	747.DR93_657	5.94e-08	55.1	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,1Y6WZ@135625|Pasteurellales	135625|Pasteurellales	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_1420329_3	1120999.JONM01000001_gene1101	5.77e-59	190.0	COG1974@1|root,COG1974@2|Bacteria,1MZFA@1224|Proteobacteria,2VU86@28216|Betaproteobacteria,2KS0A@206351|Neisseriales	206351|Neisseriales	L	Belongs to the peptidase S24 family	-	-	-	ko:K03503	-	-	-	-	ko00000,ko01000,ko01002,ko03400	-	-	-	Peptidase_S24
k59_1478531_1	1216007.AOPM01000102_gene740	1.33e-25	110.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,1RNBR@1236|Gammaproteobacteria,2Q00P@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	COG1519 3-deoxy-D-manno-octulosonic-acid transferase	kdtA	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	iECNA114_1301.ECNA114_3778,iUMNK88_1353.UMNK88_4417	Glycos_transf_1,Glycos_transf_N
k59_1067280_1	545694.TREPR_2916	1.1e-31	129.0	COG0642@1|root,COG0642@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K20974	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GGDEF,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3,SnoaL_3,dCache_1
k59_1420335_1	697281.Mahau_0820	6.35e-14	73.6	COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,42EXA@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
k59_1420335_2	1150621.SMUL_1483	7.4e-107	329.0	COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,1QTS5@1224|Proteobacteria,42MPY@68525|delta/epsilon subdivisions,2YMV7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	phosphate acetyltransferase	pta	-	2.3.1.8	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,DRTGG,PTA_PTB
k59_1538312_1	159087.Daro_3066	1.33e-50	160.0	COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,2VTYP@28216|Betaproteobacteria,2KWWW@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
k59_1538312_2	159087.Daro_3065	5.19e-107	309.0	COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,2VQ0H@28216|Betaproteobacteria,2KWFJ@206389|Rhodocyclales	206389|Rhodocyclales	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
k59_689395_1	1249480.B649_01935	1.31e-65	209.0	COG0745@1|root,COG0745@2|Bacteria,1QUJR@1224|Proteobacteria,42NQS@68525|delta/epsilon subdivisions,2YN0F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_31780_1	1123228.AUIH01000006_gene2178	1.64e-30	124.0	COG2199@1|root,COG3706@2|Bacteria,1MWHH@1224|Proteobacteria,1RRU7@1236|Gammaproteobacteria,1XJZV@135619|Oceanospirillales	135619|Oceanospirillales	T	7TMR-DISM extracellular 2	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,GGDEF
k59_1156819_1	317025.Tcr_1965	2.81e-21	92.4	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,1RM7I@1236|Gammaproteobacteria,460AT@72273|Thiotrichales	72273|Thiotrichales	C	Belongs to the heme-copper respiratory oxidase family	-	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
k59_1156819_2	717773.Thicy_1534	6.29e-73	227.0	COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,1RPU6@1236|Gammaproteobacteria,460P4@72273|Thiotrichales	72273|Thiotrichales	C	TIGRFAM cytochrome c oxidase, cbb3-type, subunit II	-	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
k59_509566_2	398527.Bphyt_4765	1.08e-41	156.0	COG0586@1|root,COG0671@1|root,COG0586@2|Bacteria,COG0671@2|Bacteria,1R0F3@1224|Proteobacteria,2VTF9@28216|Betaproteobacteria,1K0XB@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Phosphoesterase PA-phosphatase related	yabI_1	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	LssY_C,PAP2,SNARE_assoc
k59_1451785_2	1128427.KB904821_gene4061	9.01e-24	100.0	COG2199@1|root,COG3706@2|Bacteria,1G7R7@1117|Cyanobacteria,1HC6K@1150|Oscillatoriales	1117|Cyanobacteria	T	COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,SBP_bac_3
k59_1276476_1	1249480.B649_01680	1.16e-61	202.0	COG1776@1|root,COG1776@2|Bacteria,1RICK@1224|Proteobacteria,42NMU@68525|delta/epsilon subdivisions,2YMV4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Chemotaxis phosphatase CheX	-	-	-	-	-	-	-	-	-	-	-	-	CheX
k59_1276476_2	1537917.JU82_04035	1.19e-45	155.0	COG1639@1|root,COG1639@2|Bacteria,1Q1C5@1224|Proteobacteria,42T98@68525|delta/epsilon subdivisions,2YPNT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_1862750_1	1537917.JU82_00600	1.99e-235	649.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,42M69@68525|delta/epsilon subdivisions,2YN4V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
k59_1679348_1	1249480.B649_01445	3.21e-52	187.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2YMJS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,NIT,Response_reg
k59_689446_1	1304883.KI912532_gene797	9.65e-75	251.0	COG0642@1|root,COG5000@1|root,COG5002@1|root,COG0642@2|Bacteria,COG5000@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2WGK9@28216|Betaproteobacteria,2KZW1@206389|Rhodocyclales	206389|Rhodocyclales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
k59_445961_1	1123517.JOMR01000001_gene1146	2.27e-58	197.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,1RNES@1236|Gammaproteobacteria,460C3@72273|Thiotrichales	72273|Thiotrichales	E	PFAM Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k59_213035_1	1249480.B649_01765	9.83e-39	139.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,42ME0@68525|delta/epsilon subdivisions,2YMC8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_213035_2	1249480.B649_01750	2.39e-21	91.7	COG0784@1|root,COG0784@2|Bacteria,1Q9XN@1224|Proteobacteria,42YUB@68525|delta/epsilon subdivisions,2YRFD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_915835_1	177439.DP0091	1.1e-18	89.7	COG0477@1|root,COG2814@2|Bacteria,1R518@1224|Proteobacteria,43B4F@68525|delta/epsilon subdivisions,2WIQ4@28221|Deltaproteobacteria,2MIEM@213118|Desulfobacterales	28221|Deltaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_1323775_1	563040.Saut_0192	1.04e-74	237.0	COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,42M3J@68525|delta/epsilon subdivisions,2YMF8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
k59_1738133_1	1537917.JU82_01670	4.28e-102	327.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,43DMZ@68525|delta/epsilon subdivisions,2YMMS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_1862809_1	555778.Hneap_0683	5.88e-75	237.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,1RN3R@1236|Gammaproteobacteria,1WW94@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
k59_1451843_2	1304883.KI912532_gene3032	1.89e-73	225.0	COG4659@1|root,COG4659@2|Bacteria,1RDEP@1224|Proteobacteria,2VS39@28216|Betaproteobacteria,2KVKH@206389|Rhodocyclales	206389|Rhodocyclales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
k59_1386760_1	1537917.JU82_09450	3.22e-17	79.0	COG2996@1|root,COG2996@2|Bacteria,1MXC3@1224|Proteobacteria,42P2A@68525|delta/epsilon subdivisions,2YMVD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	S1 domain	-	-	-	ko:K00243	-	-	-	-	ko00000	-	-	-	S1_2
k59_572122_1	709032.Sulku_0120	1.52e-137	397.0	COG0715@1|root,COG0715@2|Bacteria,1NV0U@1224|Proteobacteria,42SS6@68525|delta/epsilon subdivisions,2YPMU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	-
k59_915888_1	159087.Daro_1312	5.99e-42	142.0	COG1961@1|root,COG1961@2|Bacteria,1R3XB@1224|Proteobacteria,2VI00@28216|Betaproteobacteria,2KWEY@206389|Rhodocyclales	206389|Rhodocyclales	L	Helix-turn-helix domain of resolvase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_7,Resolvase
k59_1620836_1	1288494.EBAPG3_10750	1.88e-10	58.9	COG0494@1|root,COG0494@2|Bacteria,1RH6N@1224|Proteobacteria,2VR3U@28216|Betaproteobacteria,3738S@32003|Nitrosomonadales	28216|Betaproteobacteria	L	Nudix hydrolase	ntpA	-	3.6.1.67	ko:K08310	ko00790,map00790	M00126	R04638	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
k59_1620836_2	580332.Slit_0984	4.33e-60	195.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,2W91H@28216|Betaproteobacteria,44W89@713636|Nitrosomonadales	28216|Betaproteobacteria	K	LysR substrate binding domain	-	-	-	ko:K21703	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k59_31908_1	1537917.JU82_11825	1.82e-110	330.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,42M14@68525|delta/epsilon subdivisions,2YMWB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Biotin carboxylase	pycA	-	6.3.4.14,6.4.1.1,6.4.1.2	ko:K01959,ko:K01961	ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko01230,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212,map01230	M00082,M00173,M00376,M00620	R00344,R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
k59_1679451_1	1123073.KB899241_gene3506	8.5e-15	73.9	COG5379@1|root,COG5379@2|Bacteria,1MWG8@1224|Proteobacteria,1RZEP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	S-adenosylmethionine diacylglycerol 3-amino-3-carboxypropyl transferase	-	-	-	ko:K13622	ko00564,map00564	-	R09072	RC00021,RC01091	ko00000,ko00001	-	-	-	DUF3419
k59_1043996_1	1537917.JU82_07955	2e-20	85.5	COG2010@1|root,COG2010@2|Bacteria,1PBN0@1224|Proteobacteria,42RGJ@68525|delta/epsilon subdivisions,2YPBP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome c	-	-	-	ko:K17223	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C
k59_1043996_2	1537917.JU82_07950	2.62e-53	171.0	COG5501@1|root,COG5501@2|Bacteria,1RH4J@1224|Proteobacteria,42TET@68525|delta/epsilon subdivisions,2YPK6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Sulfur oxidation protein SoxY	-	-	-	ko:K17226	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxY
k59_626755_2	1537917.JU82_03275	4.96e-138	411.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42MCY@68525|delta/epsilon subdivisions,2YMB3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB1	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
k59_1795698_1	709032.Sulku_1920	1.26e-119	349.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,42MGN@68525|delta/epsilon subdivisions,2YNAN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Chorismate mutase prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
k59_1044005_1	1355368.JART01000001_gene684	1.34e-08	58.2	COG2199@1|root,COG3829@1|root,COG4191@1|root,COG3706@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43DDD@68525|delta/epsilon subdivisions,2YTIA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_8,dCache_1
k59_1044005_2	1112274.KI911560_gene779	1.8e-32	131.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KKBQ@206350|Nitrosomonadales	206350|Nitrosomonadales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,SBP_bac_3
k59_1044009_1	1304883.KI912532_gene1710	2.14e-98	310.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,2VH5B@28216|Betaproteobacteria,2KVC4@206389|Rhodocyclales	206389|Rhodocyclales	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
k59_1094142_1	159087.Daro_3547	4.29e-103	308.0	COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,2VN6W@28216|Betaproteobacteria,2KVGJ@206389|Rhodocyclales	206389|Rhodocyclales	M	Glycosyltransferase Family 4	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_1212470_1	1249480.B649_09380	1.09e-159	455.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,42N2T@68525|delta/epsilon subdivisions,2YNID@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	acid membrane antigen A	amaA	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k59_1279454_1	1537917.JU82_11260	3.63e-93	280.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,42N5Q@68525|delta/epsilon subdivisions,2YMRK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
k59_1279466_1	709032.Sulku_0799	2.2e-129	396.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YM7R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Efflux pump membrane transporter	-	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_1327287_1	159087.Daro_3728	3.59e-29	109.0	COG3017@1|root,COG3017@2|Bacteria,1N5H9@1224|Proteobacteria,2VUJP@28216|Betaproteobacteria,2KX7X@206389|Rhodocyclales	206389|Rhodocyclales	M	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein	lolB	-	-	ko:K02494	-	-	-	-	ko00000	-	-	-	LolB
k59_1327287_2	243365.CV_4059	1.24e-36	132.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,2VHK3@28216|Betaproteobacteria,2KQFN@206351|Neisseriales	206351|Neisseriales	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
k59_1159755_1	159087.Daro_2854	1.3e-15	74.3	COG4796@1|root,COG4796@2|Bacteria,1RCNA@1224|Proteobacteria,2WGZA@28216|Betaproteobacteria,2KWAH@206389|Rhodocyclales	206389|Rhodocyclales	U	Bacterial type II and III secretion system protein	-	-	-	-	-	-	-	-	-	-	-	-	Secretin
k59_1159755_2	159087.Daro_2852	3.89e-51	171.0	COG3409@1|root,COG3409@2|Bacteria,1NEG1@1224|Proteobacteria,2VV5Y@28216|Betaproteobacteria,2KXXE@206389|Rhodocyclales	206389|Rhodocyclales	M	Glycosyl hydrolase family 46	-	-	3.2.1.132	ko:K01233	ko00520,ko01100,map00520,map01100	-	R02833	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_46,PG_binding_1
k59_1046676_1	1304883.KI912532_gene2410	1.01e-51	175.0	COG3522@1|root,COG3522@2|Bacteria,1MXKE@1224|Proteobacteria,2VHVK@28216|Betaproteobacteria,2KXAP@206389|Rhodocyclales	206389|Rhodocyclales	S	Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE	-	-	-	ko:K11893	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_VasE
k59_1046676_2	159087.Daro_2179	1.15e-50	164.0	COG3521@1|root,COG3521@2|Bacteria,1RGNB@1224|Proteobacteria,2VS0J@28216|Betaproteobacteria,2KZ4F@206389|Rhodocyclales	206389|Rhodocyclales	S	Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113	-	-	-	ko:K11906	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS-SciN
k59_1212529_2	709032.Sulku_2067	9.62e-124	375.0	COG0642@1|root,COG3850@1|root,COG2205@2|Bacteria,COG3850@2|Bacteria,1NRP8@1224|Proteobacteria,42Z1P@68525|delta/epsilon subdivisions,2YRFA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	HAMP domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k59_1505638_1	159087.Daro_3343	6.23e-76	251.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VI3F@28216|Betaproteobacteria,2KUP6@206389|Rhodocyclales	206389|Rhodocyclales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1505638_2	1100721.ALKO01000017_gene1681	4.44e-39	140.0	COG0446@1|root,COG0446@2|Bacteria,1PP77@1224|Proteobacteria,2W9FF@28216|Betaproteobacteria,4AA7E@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_1389803_1	709032.Sulku_1555	6.54e-35	130.0	COG0810@1|root,COG0810@2|Bacteria,1PEYQ@1224|Proteobacteria,42WJI@68525|delta/epsilon subdivisions,2YQ9A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	TonB_2,TonB_C
k59_1389803_3	1537917.JU82_10480	4.91e-55	175.0	2AJUV@1|root,31AHI@2|Bacteria,1Q5NQ@1224|Proteobacteria,431IN@68525|delta/epsilon subdivisions,2YSBH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_983390_1	1304883.KI912532_gene2332	1.2e-116	337.0	COG1211@1|root,COG1211@2|Bacteria,1MY3B@1224|Proteobacteria,2VMD6@28216|Betaproteobacteria,2KVUZ@206389|Rhodocyclales	206389|Rhodocyclales	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
k59_1389829_1	354242.CJJ81176_1304	4.53e-14	72.0	COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,42MDI@68525|delta/epsilon subdivisions,2YMJJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	malic enzyme	mez	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
k59_1389829_2	1165841.SULAR_08889	1.02e-55	177.0	2994D@1|root,2ZW7V@2|Bacteria,1Q2D1@1224|Proteobacteria,42VGB@68525|delta/epsilon subdivisions,2YQM6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_387353_1	1038922.PflQ2_2568	4.19e-19	93.2	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1YT3J@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GAF_2,GGDEF,PAS,PAS_9
k59_1742033_1	1537917.JU82_11270	5.91e-127	362.0	COG0235@1|root,COG0235@2|Bacteria,1N84G@1224|Proteobacteria,42RVW@68525|delta/epsilon subdivisions,2YP4S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
k59_1742033_2	1537917.JU82_11265	1.07e-133	386.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,42NFK@68525|delta/epsilon subdivisions,2YNST@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_1798278_1	1321778.HMPREF1982_02910	9.7e-11	60.8	COG2119@1|root,COG2119@2|Bacteria,1UFX2@1239|Firmicutes,24DHF@186801|Clostridia,26BBG@186813|unclassified Clostridiales	186801|Clostridia	S	Uncharacterized protein family UPF0016	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
k59_1159808_1	316407.85676312	4.41e-36	130.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,1S1FS@1236|Gammaproteobacteria,3XRKA@561|Escherichia	1236|Gammaproteobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstA	GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0010921,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0019220,GO:0019222,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0031323,GO:0033554,GO:0034220,GO:0035303,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051174,GO:0051179,GO:0051234,GO:0051336,GO:0051716,GO:0055085,GO:0065007,GO:0065009,GO:0071944,GO:0098656,GO:0098660,GO:0098661	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	iZ_1308.Z5217	BPD_transp_1
k59_1159808_2	1123261.AXDW01000004_gene2774	8.73e-31	116.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,1RNUF@1236|Gammaproteobacteria,1X3QF@135614|Xanthomonadales	135614|Xanthomonadales	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
k59_387355_1	1165841.SULAR_08844	4.36e-118	348.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,42NR0@68525|delta/epsilon subdivisions,2YMUN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
k59_805154_1	717773.Thicy_1178	3.09e-54	186.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,1RMXX@1236|Gammaproteobacteria,45ZSQ@72273|Thiotrichales	72273|Thiotrichales	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
k59_805154_2	1121033.AUCF01000008_gene5662	2.72e-12	62.4	2EGD6@1|root,33A4Z@2|Bacteria,1N733@1224|Proteobacteria,2UG8Q@28211|Alphaproteobacteria,2JURB@204441|Rhodospirillales	204441|Rhodospirillales	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
k59_805154_3	1123517.JOMR01000001_gene45	3.66e-32	123.0	COG2265@1|root,COG2265@2|Bacteria,1MY45@1224|Proteobacteria,1RN2B@1236|Gammaproteobacteria,461Q2@72273|Thiotrichales	72273|Thiotrichales	J	Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA)	trmA	-	2.1.1.35	ko:K00557	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_U5-meth_tr
k59_1572424_1	1121422.AUMW01000006_gene684	3.71e-81	248.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,2484X@186801|Clostridia,261P1@186807|Peptococcaceae	186801|Clostridia	K	PFAM Response regulator receiver domain	-	-	-	ko:K07775	ko02020,map02020	M00458	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_983465_1	1300005.R9RH76_9CAUD	1.08e-66	211.0	4QGM6@10239|Viruses,4QYNV@35237|dsDNA viruses  no RNA stage,4QRH4@28883|Caudovirales,4QP0P@10744|Podoviridae	10744|Podoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_983471_1	159087.Daro_0757	5.52e-43	149.0	COG1705@1|root,COG3951@1|root,COG1705@2|Bacteria,COG3951@2|Bacteria,1MX2W@1224|Proteobacteria,2VH35@28216|Betaproteobacteria,2KW3R@206389|Rhodocyclales	206389|Rhodocyclales	N	Flagellar rod assembly protein muramidase FlgJ	flgJ	-	-	ko:K02395	-	-	-	-	ko00000,ko02035	-	-	-	Glucosaminidase,Rod-binding
k59_1279599_1	709032.Sulku_1436	1.2e-139	399.0	COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,42MP8@68525|delta/epsilon subdivisions,2YNDC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
k59_325778_1	1249480.B649_02375	2.06e-124	360.0	COG0455@1|root,COG0455@2|Bacteria,1R8IW@1224|Proteobacteria,42PF7@68525|delta/epsilon subdivisions,2YM9X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Belongs to the ParA family	flhG	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	AAA_31,ParA
k59_1682029_1	1132855.KB913035_gene885	2.4e-41	156.0	COG0642@1|root,COG2203@1|root,COG3829@1|root,COG5002@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria,2KNFH@206350|Nitrosomonadales	206350|Nitrosomonadales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
k59_271949_1	1249480.B649_03700	3.19e-84	270.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2YMM8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	cation transport ATPase	copA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
k59_1623857_1	709032.Sulku_1762	7.83e-143	419.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2YN8I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Abc transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
k59_387443_1	1249480.B649_10600	5.01e-41	148.0	COG1450@1|root,COG1450@2|Bacteria,1QXWT@1224|Proteobacteria,43CKP@68525|delta/epsilon subdivisions,2YN73@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	COG1450 Type II secretory pathway component PulD	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N_2
k59_387443_2	709032.Sulku_2241	9.01e-24	97.1	COG3267@1|root,COG3267@2|Bacteria,1R16B@1224|Proteobacteria,42SY7@68525|delta/epsilon subdivisions,2YPRP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
k59_1742164_1	1249480.B649_11065	1.42e-93	287.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42MFK@68525|delta/epsilon subdivisions,2YN87@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Abc transporter	nikZ	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k59_1572521_1	522306.CAP2UW1_3367	1.32e-97	303.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,GGDEF,dCache_2
k59_919413_1	387093.SUN_0010	1.44e-100	300.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,42PDR@68525|delta/epsilon subdivisions,2YN5V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	a g-specific adenine glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
k59_325843_1	709032.Sulku_1002	1.89e-76	243.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,42NC6@68525|delta/epsilon subdivisions,2YMJV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
k59_858907_1	1123367.C666_04070	4.5e-13	69.3	COG1414@1|root,COG1414@2|Bacteria,1NMZV@1224|Proteobacteria,2VYEZ@28216|Betaproteobacteria,2KYSE@206389|Rhodocyclales	206389|Rhodocyclales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1623906_1	580332.Slit_0462	9.79e-83	262.0	COG0477@1|root,COG0477@2|Bacteria,1QUAG@1224|Proteobacteria,2WHA4@28216|Betaproteobacteria	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	ko:K08227	-	-	-	-	ko00000,ko02000	2.A.1.42	-	-	MFS_1
k59_1623906_2	1385521.N803_08165	2.22e-18	85.1	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2GM5Q@201174|Actinobacteria,4FEMU@85021|Intrasporangiaceae	201174|Actinobacteria	E	MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
k59_216256_2	709032.Sulku_1767	2.71e-162	458.0	COG2214@1|root,COG2214@2|Bacteria	2|Bacteria	O	Heat shock protein DnaJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
k59_216256_3	929558.SMGD1_1852	2.33e-10	59.7	COG1187@1|root,COG1187@2|Bacteria,1MU6M@1224|Proteobacteria,42RD2@68525|delta/epsilon subdivisions,2YP0D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	rsuA	-	5.4.99.19	ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_35143_1	1537917.JU82_04615	2.58e-50	163.0	COG0711@1|root,COG0711@2|Bacteria,1Q2G9@1224|Proteobacteria,42VN4@68525|delta/epsilon subdivisions,2YQBE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the ATPase B chain family	atpF'	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
k59_1096803_1	392500.Swoo_4576	1.22e-25	110.0	COG5184@1|root,COG5184@2|Bacteria,1QUGV@1224|Proteobacteria,1T1YH@1236|Gammaproteobacteria,2QB15@267890|Shewanellaceae	1236|Gammaproteobacteria	DZ	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_857136_1	709032.Sulku_1956	5.67e-60	202.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42N03@68525|delta/epsilon subdivisions,2YNMG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	PFAM Methyl-accepting chemotaxis protein (MCP) signaling domain	-	-	-	ko:K03406,ko:K05875	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,MCPsignal
k59_980663_1	1249480.B649_00035	1.68e-126	375.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42N6Y@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE5,GAF,HATPase_c,HisKA,PAS_4,Response_reg,dCache_2,sCache_2
k59_323491_2	709032.Sulku_0684	9.94e-122	352.0	COG0847@1|root,COG0847@2|Bacteria,1RGGD@1224|Proteobacteria,42ZIP@68525|delta/epsilon subdivisions,2YRQP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG0847 DNA polymerase III epsilon subunit and related 3'-5'	-	-	2.7.7.7	ko:K02342,ko:K10857	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_323494_1	357804.Ping_0949	3.76e-36	139.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2QIXR@267894|Psychromonadaceae	1236|Gammaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,MASE3,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
k59_90401_1	1537917.JU82_04585	7.06e-23	95.1	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,42M40@68525|delta/epsilon subdivisions,2YMGX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
k59_90401_2	563040.Saut_0764	3.45e-40	134.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,42THK@68525|delta/epsilon subdivisions,2YQ0A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
k59_510374_1	159087.Daro_3381	2.46e-130	373.0	COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,2VJPI@28216|Betaproteobacteria,2KUCS@206389|Rhodocyclales	206389|Rhodocyclales	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
k59_1503398_1	709032.Sulku_1524	3.34e-09	57.8	COG0659@1|root,COG0664@1|root,COG0659@2|Bacteria,COG0664@2|Bacteria,1MVWV@1224|Proteobacteria,42MMU@68525|delta/epsilon subdivisions,2YTMR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	STAS domain	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp,cNMP_binding
k59_1503398_2	387092.NIS_1777	1.5e-31	117.0	COG1648@1|root,COG1648@2|Bacteria,1RB3H@1224|Proteobacteria,42QT2@68525|delta/epsilon subdivisions,2YP97@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	COG1648 Siroheme synthase (precorrin-2 oxidase ferrochelatase domain)	-	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_7,Sirohm_synth_M
k59_1680038_1	748247.AZKH_1917	1.05e-27	110.0	COG2828@1|root,COG2828@2|Bacteria,1MXVV@1224|Proteobacteria,2VJAW@28216|Betaproteobacteria	28216|Betaproteobacteria	S	AcnD-accessory protein PrpF	-	-	-	-	-	-	-	-	-	-	-	-	PrpF
k59_802899_2	56780.SYN_02290	2.46e-30	122.0	COG3941@1|root,COG3941@2|Bacteria,1RC0N@1224|Proteobacteria	1224|Proteobacteria	S	tape measure	-	-	-	-	-	-	-	-	-	-	-	-	PhageMin_Tail
k59_802905_1	159087.Daro_0664	9.63e-47	160.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2VI01@28216|Betaproteobacteria,2KU9I@206389|Rhodocyclales	206389|Rhodocyclales	E	Aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
k59_158168_1	709032.Sulku_1126	4.53e-117	370.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2YMRQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_1387496_1	709032.Sulku_2358	7.16e-12	64.3	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,42N67@68525|delta/epsilon subdivisions,2YMDK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
k59_1387496_2	709032.Sulku_2359	4.58e-115	333.0	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,42NGT@68525|delta/epsilon subdivisions,2YN0R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
k59_1739117_1	159087.Daro_0343	6.28e-59	183.0	COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,2VR8I@28216|Betaproteobacteria,2KW6N@206389|Rhodocyclales	206389|Rhodocyclales	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
k59_1739117_3	338969.Rfer_4221	1.89e-15	68.6	COG0257@1|root,COG0257@2|Bacteria,1NGEI@1224|Proteobacteria,2VXPQ@28216|Betaproteobacteria,4AFV9@80864|Comamonadaceae	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
k59_1387514_1	159087.Daro_1205	6.69e-122	361.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,2VI1K@28216|Betaproteobacteria,2KUQ9@206389|Rhodocyclales	206389|Rhodocyclales	FP	Exopolyphosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
k59_1739132_1	1249480.B649_09945	7e-79	241.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
k59_1570084_1	1244083.CSUNSWCD_1909	7.46e-19	78.2	COG1328@1|root,COG1328@2|Bacteria,1N8MB@1224|Proteobacteria,42V5U@68525|delta/epsilon subdivisions,2YQAB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Anaerobic ribonucleoside-triphosphate reductase	nrdD2	-	-	-	-	-	-	-	-	-	-	-	NRDD
k59_1570084_2	1249480.B649_06210	2.1e-38	130.0	COG2863@1|root,COG2863@2|Bacteria,1NFMX@1224|Proteobacteria,42VGD@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	cytochrome	cyf	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,Cytochrome_CBB3
k59_1452390_1	1537917.JU82_10860	6.35e-179	500.0	COG0648@1|root,COG0648@2|Bacteria,1MX4Y@1224|Proteobacteria,42MYE@68525|delta/epsilon subdivisions,2YMF4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
k59_1503476_1	305700.B447_13159	1.16e-83	261.0	COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,2VKVT@28216|Betaproteobacteria,2M03J@206389|Rhodocyclales	206389|Rhodocyclales	I	COG2067 Long-chain fatty acid transport protein	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k59_627617_1	159087.Daro_0124	2.16e-46	150.0	COG4575@1|root,COG4575@2|Bacteria,1N6X7@1224|Proteobacteria,2WFR8@28216|Betaproteobacteria,2KX05@206389|Rhodocyclales	206389|Rhodocyclales	S	Bacterial protein of unknown function (DUF883)	-	-	-	-	-	-	-	-	-	-	-	-	DUF883
k59_627617_2	159087.Daro_0123	1.13e-132	379.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,2VI74@28216|Betaproteobacteria,2KV3I@206389|Rhodocyclales	206389|Rhodocyclales	L	Endonuclease/Exonuclease/phosphatase family	xthA2	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
k59_213891_1	709032.Sulku_1379	2.67e-82	256.0	COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,42PB4@68525|delta/epsilon subdivisions,2YNJ9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	ko:K15576	ko00910,ko02010,map00910,map02010	M00438	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16.1,3.A.1.16.2	-	-	NMT1_2
k59_1621579_1	472759.Nhal_3928	6.63e-28	110.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,1RM7Q@1236|Gammaproteobacteria,1WXFU@135613|Chromatiales	135613|Chromatiales	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k59_1621579_2	1217718.ALOU01000062_gene454	1.03e-24	101.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,2VP72@28216|Betaproteobacteria,1K3M1@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
k59_1094724_1	398580.Dshi_0789	8.67e-13	74.3	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,2TRC5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)	kefC	-	-	ko:K03455,ko:K11745,ko:K11747	-	-	-	-	ko00000,ko02000	2.A.37,2.A.37.1.1,2.A.37.1.2	-	-	Na_H_Exchanger,TrkA_N
k59_1863523_1	1070319.CAGGBEG34_330021	1.03e-13	66.2	COG3093@1|root,COG3093@2|Bacteria,1N76J@1224|Proteobacteria,2VVD3@28216|Betaproteobacteria,1KFQD@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
k59_1680139_2	709032.Sulku_0137	2.08e-144	421.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,42ND6@68525|delta/epsilon subdivisions,2YN5S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
k59_1452443_1	709032.Sulku_0003	3.21e-159	467.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,42M7M@68525|delta/epsilon subdivisions,2YMUW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_1739257_2	1537917.JU82_01275	1.67e-18	85.1	COG0665@1|root,COG0665@2|Bacteria,1Q0BQ@1224|Proteobacteria,42RXA@68525|delta/epsilon subdivisions,2YP66@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	COGs COG0665 Glycine D-amino acid oxidase (deaminating)	-	-	2.1.1.61	ko:K15461	-	-	R00601,R08702	RC00003,RC00053,RC00060,RC01483	ko00000,ko01000,ko03016	-	-	-	DAO
k59_916863_1	1249480.B649_08860	9.03e-99	297.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,42N2A@68525|delta/epsilon subdivisions,2YMD3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
k59_1044725_1	159087.Daro_0459	9.68e-123	379.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,2KUIU@206389|Rhodocyclales	206389|Rhodocyclales	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1739273_2	1537917.JU82_09730	1.36e-65	211.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,42M3R@68525|delta/epsilon subdivisions,2YN91@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
k59_627693_2	1249480.B649_02375	7.69e-38	134.0	COG0455@1|root,COG0455@2|Bacteria,1R8IW@1224|Proteobacteria,42PF7@68525|delta/epsilon subdivisions,2YM9X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Belongs to the ParA family	flhG	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	AAA_31,ParA
k59_270324_1	709032.Sulku_2173	4.85e-40	135.0	2AK35@1|root,31ASX@2|Bacteria,1Q62J@1224|Proteobacteria,42W2T@68525|delta/epsilon subdivisions,2YQDE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_32806_1	1537917.JU82_00925	2.11e-101	307.0	28NUA@1|root,2ZBSQ@2|Bacteria,1QE31@1224|Proteobacteria,42Z7U@68525|delta/epsilon subdivisions,2YR9R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_732981_1	1537917.JU82_05105	1.6e-51	183.0	COG3164@1|root,COG3164@2|Bacteria,1QUYX@1224|Proteobacteria,43CES@68525|delta/epsilon subdivisions,2YTC9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
k59_510540_1	1537917.JU82_11315	4.5e-103	308.0	COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,42P1M@68525|delta/epsilon subdivisions,2YN96@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Peptidase M48	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
k59_213971_1	1537917.JU82_11875	1.78e-86	280.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,42N8X@68525|delta/epsilon subdivisions,2YMGZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_1570199_1	1167006.UWK_03288	4.48e-108	332.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,42M9Q@68525|delta/epsilon subdivisions,2WKKT@28221|Deltaproteobacteria,2MPSR@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	ko:K02567	ko00910,ko01120,map00910,map01120	M00529,M00530	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
k59_90523_1	709032.Sulku_2216	1.23e-110	320.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,42RV5@68525|delta/epsilon subdivisions,2YP89@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
k59_270338_1	1304883.KI912532_gene2060	5.52e-109	323.0	COG1485@1|root,COG1485@2|Bacteria,1MUUW@1224|Proteobacteria,2VHQX@28216|Betaproteobacteria,2KUMJ@206389|Rhodocyclales	206389|Rhodocyclales	S	AFG1-like ATPase	afg	-	-	ko:K06916	-	-	-	-	ko00000,ko03036	-	-	-	AFG1_ATPase
k59_733005_1	1500897.JQNA01000001_gene6352	6.15e-05	44.3	COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,2VH28@28216|Betaproteobacteria,1K1WX@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Molybdenum cofactor synthesis domain protein	mogA	-	2.7.7.75	ko:K03831	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
k59_733005_2	159087.Daro_0596	2.29e-73	224.0	COG3028@1|root,COG3028@2|Bacteria,1MZ4R@1224|Proteobacteria,2VSGZ@28216|Betaproteobacteria,2KWJZ@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the UPF0307 family	-	-	-	ko:K09889	-	-	-	-	ko00000,ko03009	-	-	-	DUF615
k59_1048164_2	994573.T472_0200030	6.52e-08	53.5	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,249KK@186801|Clostridia,36EFN@31979|Clostridiaceae	186801|Clostridia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
k59_1574131_1	159087.Daro_1203	1.58e-108	323.0	COG2199@1|root,COG3706@2|Bacteria,1R59V@1224|Proteobacteria,2VN7N@28216|Betaproteobacteria,2KUR6@206389|Rhodocyclales	206389|Rhodocyclales	T	COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
k59_1098129_1	387093.SUN_1625	2.67e-82	255.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,PQQ_2,SBBP
k59_806541_1	159087.Daro_1785	7.53e-59	190.0	COG1161@1|root,COG1161@2|Bacteria,1MV5H@1224|Proteobacteria,2VHAG@28216|Betaproteobacteria,2KVMC@206389|Rhodocyclales	206389|Rhodocyclales	S	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity	-	-	-	ko:K14540	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1
k59_1391244_1	387093.SUN_0280	2.65e-114	338.0	COG0842@1|root,COG0842@2|Bacteria,1NG32@1224|Proteobacteria,43APA@68525|delta/epsilon subdivisions,2YT2R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_3
k59_1866922_2	709032.Sulku_1444	3.35e-43	153.0	COG0579@1|root,COG0579@2|Bacteria,1MUCC@1224|Proteobacteria,42M2Q@68525|delta/epsilon subdivisions,2YMYG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Malate quinone- oxidoreductase	mqo	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.1.5.4	ko:K00116	ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00009,M00011	R00360,R00361,R01257	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0086	Mqo
k59_1625952_2	159087.Daro_3512	2e-52	166.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,2VU4V@28216|Betaproteobacteria,2KXFI@206389|Rhodocyclales	206389|Rhodocyclales	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k59_1625952_3	159087.Daro_3513	7.82e-102	298.0	COG3005@1|root,COG3005@2|Bacteria,1MWV2@1224|Proteobacteria,2VMSB@28216|Betaproteobacteria,2KV5G@206389|Rhodocyclales	206389|Rhodocyclales	C	cytochrome c-type protein	-	-	-	ko:K02569	-	-	-	-	ko00000	-	-	-	Cytochrom_NNT
k59_1391273_1	563040.Saut_1560	9.36e-36	133.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
k59_921125_1	748247.AZKH_1530	3.19e-36	135.0	COG0642@1|root,COG2205@2|Bacteria,1QV1H@1224|Proteobacteria,2WGTQ@28216|Betaproteobacteria,2KVWB@206389|Rhodocyclales	206389|Rhodocyclales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_921125_2	748247.AZKH_1529	3.08e-42	144.0	COG0745@1|root,COG0745@2|Bacteria,1RA00@1224|Proteobacteria,2VRNX@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Response regulators consisting of a CheY-like receiver domain and a	colR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_1161144_1	159087.Daro_0708	2.96e-111	334.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,2VHTQ@28216|Betaproteobacteria,2KVHB@206389|Rhodocyclales	206389|Rhodocyclales	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
k59_1391294_1	1537917.JU82_00660	5.74e-136	405.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,43BRF@68525|delta/epsilon subdivisions,2YNGV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	TonB dependent receptor	-	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
k59_513788_1	29581.BW37_03998	2.01e-20	95.1	COG0457@1|root,COG0457@2|Bacteria,1RKBG@1224|Proteobacteria,2VQFW@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_8
k59_513788_2	1123517.JOMR01000001_gene886	9.57e-09	57.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,460A8@72273|Thiotrichales	72273|Thiotrichales	NU	Secretion system protein	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
k59_985549_1	1249480.B649_10400	5.75e-123	374.0	COG0715@1|root,COG0834@1|root,COG2199@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42UTN@68525|delta/epsilon subdivisions,2YTHQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EPT	NMT1/THI5 like	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	GGDEF,NMT1,SBP_bac_3
k59_1574224_1	159087.Daro_0682	8.41e-119	352.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,2VHQS@28216|Betaproteobacteria,2KVUJ@206389|Rhodocyclales	206389|Rhodocyclales	K	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_4,Sigma54_activat
k59_694427_1	1049564.TevJSym_au00570	2.15e-12	65.5	COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,1S6B5@1236|Gammaproteobacteria,1J64J@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	smrA	-	-	-	-	-	-	-	-	-	-	-	Smr
k59_694427_2	439235.Dalk_5177	6.95e-25	111.0	COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,42MYF@68525|delta/epsilon subdivisions,2WJE3@28221|Deltaproteobacteria,2MI4M@213118|Desulfobacterales	28221|Deltaproteobacteria	L	TIGRFAM single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
k59_1391304_1	1249480.B649_01625	4.75e-54	189.0	COG2203@1|root,COG2206@1|root,COG3829@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,COG3829@2|Bacteria,1RAQS@1224|Proteobacteria,42QQI@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	PFAM Metal-dependent phosphohydrolase, HD	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,GAF_2,HD,HD_5,PAS,PAS_4,PAS_8,PAS_9,Response_reg,sCache_2
k59_1799862_1	159087.Daro_1154	7.95e-55	182.0	COG4398@1|root,COG4398@2|Bacteria,1RBRR@1224|Proteobacteria,2VQ7K@28216|Betaproteobacteria,2KWHA@206389|Rhodocyclales	206389|Rhodocyclales	S	FIST_C	-	-	-	-	-	-	-	-	-	-	-	-	FIST_C
k59_1799862_2	159087.Daro_1153	9.65e-15	69.3	2AFCJ@1|root,315C6@2|Bacteria,1RH66@1224|Proteobacteria,2VSTN@28216|Betaproteobacteria,2KWN8@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of unknown function (DUF1841)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1841
k59_1456445_1	1537917.JU82_01785	1.29e-212	594.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,42NKY@68525|delta/epsilon subdivisions,2YN43@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
k59_921235_1	1249480.B649_05660	1.03e-95	297.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2YMMT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_1626124_1	1249480.B649_04390	1.35e-88	276.0	COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,42Q77@68525|delta/epsilon subdivisions,2YMR9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Sulfite reductase beta subunit (hemoprotein)	-	-	1.8.7.1	ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00859,R03600	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr,TusA
k59_1626124_2	1205683.CAKR01000014_gene148	1.97e-06	48.9	COG2895@1|root,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,1RME4@1236|Gammaproteobacteria,41F5S@629|Yersinia	1236|Gammaproteobacteria	H	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0004779,GO:0004781,GO:0005488,GO:0005525,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0070566,GO:0097159,GO:0097367,GO:1901265,GO:1901363	2.7.7.4	ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	iECO103_1326.ECO103_3293	GTP_EFTU
k59_1799912_1	1249480.B649_02255	9.32e-125	361.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,42MVM@68525|delta/epsilon subdivisions,2YMMR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxC
k59_1799919_1	1479235.KK366039_gene1054	3.16e-45	155.0	COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,1RNPS@1236|Gammaproteobacteria,1XJNB@135619|Oceanospirillales	135619|Oceanospirillales	M	(Lipo)protein	vacJ	-	-	ko:K04754	-	-	-	-	ko00000	-	-	-	MlaA
k59_1329701_1	1295642.H839_11214	2.3e-88	281.0	COG3211@1|root,COG3211@2|Bacteria,1UYPE@1239|Firmicutes,4HCRC@91061|Bacilli,1WHE1@129337|Geobacillus	91061|Bacilli	S	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
k59_161413_1	387093.SUN_0974	2.49e-07	53.5	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,42NGE@68525|delta/epsilon subdivisions,2YN37@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0471 Di- and tricarboxylate	-	-	-	ko:K03319	-	-	-	-	ko00000	2.A.47	-	-	Na_sulph_symp
k59_1214449_2	935567.JAES01000030_gene2856	6.74e-08	56.6	COG1399@1|root,COG1399@2|Bacteria	2|Bacteria	K	metal-binding, possibly nucleic acid-binding protein	yceD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
k59_1214449_3	1089439.KB902242_gene1109	0.000201	40.4	COG0333@1|root,COG0333@2|Bacteria,1N6RF@1224|Proteobacteria,1SC9G@1236|Gammaproteobacteria,46158@72273|Thiotrichales	72273|Thiotrichales	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
k59_1048356_1	1165841.SULAR_01583	7.97e-28	104.0	2AYIJ@1|root,319EA@2|Bacteria,1Q2GZ@1224|Proteobacteria,42VPA@68525|delta/epsilon subdivisions,2YQB9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1048356_2	749222.Nitsa_1250	3.01e-29	107.0	COG1254@1|root,COG1254@2|Bacteria,1Q88S@1224|Proteobacteria,42WDB@68525|delta/epsilon subdivisions,2YQCS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the acylphosphatase family	-	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
k59_1048356_3	1165841.SULAR_01593	1.19e-35	120.0	2AKC8@1|root,31B36@2|Bacteria,1Q6TQ@1224|Proteobacteria,433T1@68525|delta/epsilon subdivisions,2YSPZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_480288_1	709032.Sulku_1311	1.48e-67	208.0	COG2077@1|root,COG2077@2|Bacteria,1Q5WV@1224|Proteobacteria,431ZJ@68525|delta/epsilon subdivisions,2YSAN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	AhpC/TSA family	-	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	Redoxin
k59_480288_2	1249480.B649_06905	5.18e-41	138.0	COG0666@1|root,COG0666@2|Bacteria,1Q4NQ@1224|Proteobacteria,42VS5@68525|delta/epsilon subdivisions,2YQIE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_4
k59_1419237_1	159087.Daro_2188	4.8e-83	273.0	COG3523@1|root,COG3523@2|Bacteria,1MV3D@1224|Proteobacteria,2VJ0M@28216|Betaproteobacteria,2KV24@206389|Rhodocyclales	206389|Rhodocyclales	S	function. A few members resemble the ImcF protein, which has been proposed to be involved in Vibrio cholerae cell surface reorganisation that results in increased adherence to epithelial cells line and increased conjugation frequency	-	-	-	ko:K11891	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	IcmF-related,IcmF_C,ImcF-related_N
k59_656976_1	1537915.JU57_01850	7.36e-40	140.0	COG2968@1|root,COG2968@2|Bacteria	2|Bacteria	S	cellular response to heat	-	-	-	ko:K07221,ko:K09807	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	OMP_b-brl,SIMPL
k59_1300575_2	1537917.JU82_04310	1.3e-91	271.0	COG0741@1|root,COG0741@2|Bacteria,1Q5W3@1224|Proteobacteria,431XB@68525|delta/epsilon subdivisions,2YSCH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	lytic transglycosylase activity	-	-	-	-	-	-	-	-	-	-	-	-	SLT
k59_1300575_3	709032.Sulku_1612	3.91e-62	197.0	29DMK@1|root,300JF@2|Bacteria,1Q6BD@1224|Proteobacteria,432QV@68525|delta/epsilon subdivisions,2YSKF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1300575_4	1537917.JU82_04320	4.59e-50	160.0	2BR7U@1|root,32K64@2|Bacteria,1Q2P2@1224|Proteobacteria,431JX@68525|delta/epsilon subdivisions,2YSDV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1419250_1	1537917.JU82_03225	4.95e-104	323.0	COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2YMB9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	chemotaxis protein	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k59_596923_1	375286.mma_3355	1.65e-15	82.8	COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,2VHY8@28216|Betaproteobacteria,472QP@75682|Oxalobacteraceae	28216|Betaproteobacteria	NU	Neisseria PilC beta-propeller domain	pilY1	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC
k59_1066237_1	1165841.SULAR_02698	3.65e-52	182.0	COG4907@1|root,COG4907@2|Bacteria,1MXPY@1224|Proteobacteria,42MA5@68525|delta/epsilon subdivisions,2YRC9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
k59_890165_1	929558.SMGD1_2124	2.33e-29	122.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,42N78@68525|delta/epsilon subdivisions,2YMYH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
k59_1066254_1	1385517.N800_12310	6.88e-89	274.0	COG2829@1|root,COG2829@2|Bacteria,1PC8I@1224|Proteobacteria,1RMJH@1236|Gammaproteobacteria,1X44M@135614|Xanthomonadales	135614|Xanthomonadales	M	phospholipase	pldA	-	3.1.1.32,3.1.1.4	ko:K01058	ko00564,ko00565,ko00590,ko00591,ko00592,ko01100,ko01110,map00564,map00565,map00590,map00591,map00592,map01100,map01110	-	R01315,R01316,R01317,R02053,R02054,R04034,R07064,R07379,R07387,R07859,R07860	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko01000	-	-	-	PLA1
k59_890180_2	1196322.A370_00805	8.52e-09	60.1	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TSK4@1239|Firmicutes,24DXH@186801|Clostridia,36R74@31979|Clostridiaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC,Response_reg
k59_596943_1	929558.SMGD1_1774	5.19e-22	100.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Histidine kinase A domain protein	rpfC	-	2.7.13.3	ko:K10715	ko02020,ko02024,map02020,map02024	M00517	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CHASE8,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_9,Response_reg
k59_1711909_1	1537917.JU82_02995	2.04e-187	525.0	COG0226@1|root,COG0226@2|Bacteria,1MUAZ@1224|Proteobacteria,42NM3@68525|delta/epsilon subdivisions,2YMMK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
k59_771561_1	1304883.KI912532_gene71	9.15e-35	127.0	COG4972@1|root,COG4972@2|Bacteria,1N0HS@1224|Proteobacteria,2VQYY@28216|Betaproteobacteria,2KWGV@206389|Rhodocyclales	206389|Rhodocyclales	NU	Pilus assembly protein	-	-	-	ko:K12279	-	-	-	-	ko00000,ko02044	-	-	-	-
k59_771561_2	159087.Daro_0888	1.38e-11	66.2	COG3210@1|root,COG3391@1|root,COG3210@2|Bacteria,COG3391@2|Bacteria,1R4VM@1224|Proteobacteria,2VPC1@28216|Betaproteobacteria,2KWIJ@206389|Rhodocyclales	206389|Rhodocyclales	U	domain, Protein	-	-	-	ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	-
k59_1066269_1	1003200.AXXA_21935	3.09e-69	234.0	COG1629@1|root,COG4771@2|Bacteria,1R4PY@1224|Proteobacteria,2VZJH@28216|Betaproteobacteria	28216|Betaproteobacteria	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_480353_1	709032.Sulku_1474	5.63e-106	325.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YMHP@29547|Epsilonproteobacteria	68525|delta/epsilon subdivisions	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_9,dCache_2
k59_360936_1	1123393.KB891316_gene1285	2.67e-36	131.0	2CJ6B@1|root,32S9B@2|Bacteria,1N2I4@1224|Proteobacteria,2VV7N@28216|Betaproteobacteria,1KTHT@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Thermostable hemolysin	-	-	-	-	-	-	-	-	-	-	-	-	T_hemolysin
k59_1419303_1	1249480.B649_11100	9.18e-78	236.0	COG5456@1|root,COG5456@2|Bacteria,1Q27X@1224|Proteobacteria,42V4G@68525|delta/epsilon subdivisions,2YQE8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	FixH	-	-	-	-	-	-	-	-	-	-	-	-	FixH,YtkA
k59_480363_1	713586.KB900536_gene2072	1.91e-10	64.3	COG4972@1|root,COG4972@2|Bacteria,1N0HS@1224|Proteobacteria,1SAQC@1236|Gammaproteobacteria,1X1R6@135613|Chromatiales	135613|Chromatiales	NU	Pilus assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_184588_1	159087.Daro_3778	3.47e-219	625.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,2VJ61@28216|Betaproteobacteria,2KUQ8@206389|Rhodocyclales	206389|Rhodocyclales	S	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_1594685_2	580332.Slit_0076	1.16e-27	102.0	COG3369@1|root,COG3369@2|Bacteria,1N6QZ@1224|Proteobacteria,2VWV2@28216|Betaproteobacteria	28216|Betaproteobacteria	S	SMART zinc finger, CDGSH-type domain protein	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
k59_1594686_1	709032.Sulku_0243	5.56e-116	346.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,42MTY@68525|delta/epsilon subdivisions,2YMHI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
k59_1066302_1	709032.Sulku_1408	2.26e-106	323.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,42N7A@68525|delta/epsilon subdivisions,2YMRE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	lytic murein transglycosylase	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
k59_1244186_1	1249480.B649_10700	1.08e-137	425.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,43DMZ@68525|delta/epsilon subdivisions,2YMMS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_420286_1	1249480.B649_00745	8.06e-99	296.0	COG1373@1|root,COG1373@2|Bacteria,1QP8R@1224|Proteobacteria,42SQ9@68525|delta/epsilon subdivisions,2YPG4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	ATPase (AAA	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14
k59_128004_2	1537917.JU82_09325	1.24e-38	134.0	COG1381@1|root,COG1381@2|Bacteria,1QAJR@1224|Proteobacteria,42NUJ@68525|delta/epsilon subdivisions,2YPCX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	RecO N terminal	-	-	-	-	-	-	-	-	-	-	-	-	RecO_N_2
k59_1183730_1	709032.Sulku_0874	1.05e-77	249.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,42MGF@68525|delta/epsilon subdivisions,2YN0E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the UbiD family	menA	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0396	UbiD
k59_1183730_2	1249480.B649_07710	1.13e-59	185.0	28QM5@1|root,319KE@2|Bacteria,1Q3DZ@1224|Proteobacteria,42X5X@68525|delta/epsilon subdivisions,2YQT9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_771606_1	1297742.A176_05134	3.88e-09	60.5	COG1589@1|root,COG1589@2|Bacteria,1RDX7@1224|Proteobacteria,42VCZ@68525|delta/epsilon subdivisions,2WRVM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Essential cell division protein	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
k59_771606_2	351348.Maqu_2450	6.15e-31	118.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,1RMTM@1236|Gammaproteobacteria,4659J@72275|Alteromonadaceae	1236|Gammaproteobacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
k59_539881_2	159087.Daro_1846	1.84e-35	124.0	COG1580@1|root,COG1580@2|Bacteria,1PX2B@1224|Proteobacteria,2VYSY@28216|Betaproteobacteria,2KZID@206389|Rhodocyclales	206389|Rhodocyclales	N	Controls the rotational direction of flagella during chemotaxis	-	-	-	ko:K02415	-	-	-	-	ko00000,ko02035	-	-	-	FliL
k59_1359072_1	941824.TCEL_00606	3.38e-101	302.0	COG2309@1|root,COG2309@2|Bacteria,1TP65@1239|Firmicutes,24AR8@186801|Clostridia,36E9B@31979|Clostridiaceae	186801|Clostridia	E	aminopeptidase	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
k59_1711975_1	709032.Sulku_0921	4.3e-99	316.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2YMA1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
k59_1711975_2	1537917.JU82_06160	2.83e-26	100.0	COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,42SI7@68525|delta/epsilon subdivisions,2YP7Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the UPF0178 family	-	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
k59_1244218_2	1249480.B649_00605	2.84e-22	91.3	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,42MG4@68525|delta/epsilon subdivisions,2YME4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	response regulator	ompR	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_184634_1	314285.KT71_06409	1.16e-29	129.0	COG0642@1|root,COG0642@2|Bacteria,1NXDJ@1224|Proteobacteria,1SJMI@1236|Gammaproteobacteria,1J8U5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
k59_1594742_1	563040.Saut_1187	1.41e-34	127.0	2BVW3@1|root,2Z7TB@2|Bacteria,1MY60@1224|Proteobacteria,42QE2@68525|delta/epsilon subdivisions,2YNKM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	5'-nucleotidase	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5-nucleotidase
k59_1594742_2	929712.KI912613_gene3576	3.81e-18	82.0	COG0454@1|root,COG0456@2|Bacteria,2GJJZ@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
k59_420344_1	709032.Sulku_1960	2.49e-84	281.0	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG5000@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,COG5000@2|Bacteria,1RGKE@1224|Proteobacteria	1224|Proteobacteria	T	GAF domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,GAF,GAF_2,HATPase_c,HisKA,HisKA_2,HisKA_3,PAS,PAS_3,PAS_4,PAS_9,Pkinase,STAS,SpoIIE
k59_1300679_1	1537917.JU82_01250	4.52e-91	283.0	2AJGC@1|root,31A2T@2|Bacteria,1Q4TA@1224|Proteobacteria,42ZUH@68525|delta/epsilon subdivisions,2YRV9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1126297_1	709032.Sulku_0529	8.92e-115	348.0	COG0726@1|root,COG1649@1|root,COG0726@2|Bacteria,COG1649@2|Bacteria,1MWR2@1224|Proteobacteria,43AG1@68525|delta/epsilon subdivisions,2YT1V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Hypothetical glycosyl hydrolase family 13	-	-	-	ko:K11931	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000	-	-	-	GHL13,Polysacc_deac_1
k59_1712034_2	1537917.JU82_11465	6.27e-46	155.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,42NQB@68525|delta/epsilon subdivisions,2YMSA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	iIT341.HP0961	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
k59_420370_2	709032.Sulku_1044	1.9e-103	317.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,42MXV@68525|delta/epsilon subdivisions,2YRFR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Cyt-b5,POR,POR_N
k59_1594784_1	1249480.B649_09495	2.79e-23	98.6	COG0223@1|root,COG1024@1|root,COG0223@2|Bacteria,COG1024@2|Bacteria,1MWYJ@1224|Proteobacteria,42PAJ@68525|delta/epsilon subdivisions,2YNKB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	IJ	Enoyl-CoA hydratase/isomerase	-	-	-	ko:K19640	-	-	-	-	ko00000,ko02022	-	-	-	ECH_1,Formyl_trans_C,Formyl_trans_N
k59_1594784_2	1249480.B649_09490	1.94e-70	213.0	COG0375@1|root,COG0375@2|Bacteria,1MZJH@1224|Proteobacteria,42TGG@68525|delta/epsilon subdivisions,2YPWP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
k59_244579_1	1165841.SULAR_04302	1.85e-121	364.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,42N1K@68525|delta/epsilon subdivisions,2YMYX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1g,tRNA_bind
k59_1419466_2	159087.Daro_1221	6.87e-23	98.6	COG1305@1|root,COG1305@2|Bacteria,1MY5V@1224|Proteobacteria,2VKGI@28216|Betaproteobacteria,2KW58@206389|Rhodocyclales	206389|Rhodocyclales	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
k59_1244311_2	326298.Suden_0410	1.41e-07	53.9	COG2165@1|root,COG2165@2|Bacteria,1QUIZ@1224|Proteobacteria,43BJB@68525|delta/epsilon subdivisions,2YTBR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_539998_1	159087.Daro_1635	1.27e-171	497.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,2VHE1@28216|Betaproteobacteria,2KVCU@206389|Rhodocyclales	206389|Rhodocyclales	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
k59_1831197_2	709032.Sulku_1735	2.02e-39	140.0	COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,42M78@68525|delta/epsilon subdivisions,2YMR1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
k59_184731_1	1537917.JU82_02865	1.98e-127	385.0	COG4206@1|root,COG4206@2|Bacteria,1QUGQ@1224|Proteobacteria,42PHJ@68525|delta/epsilon subdivisions,2YNKV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_67213_1	395494.Galf_1630	1.79e-89	280.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,1RH0R@1224|Proteobacteria,2VRQD@28216|Betaproteobacteria	28216|Betaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
k59_540017_1	159087.Daro_0350	2.36e-27	110.0	COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,2VHI3@28216|Betaproteobacteria,2KV76@206389|Rhodocyclales	206389|Rhodocyclales	I	Long-chain fatty acid transport protein	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k59_540017_2	477184.KYC_27127	4.33e-14	71.6	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2VH0Y@28216|Betaproteobacteria,3T2Z0@506|Alcaligenaceae	28216|Betaproteobacteria	I	enoyl-CoA hydratase	fadJ	-	1.1.1.157,1.1.1.35,4.2.1.17,5.1.2.3	ko:K00074,ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R01976,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R05576,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
k59_1713761_2	709032.Sulku_0577	3.1e-64	196.0	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,42VNC@68525|delta/epsilon subdivisions,2YQ9K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	-	-	-	-	-	-	-	-	-	Haemolytic
k59_68526_1	1249480.B649_00290	6.1e-71	228.0	2DCNX@1|root,2ZESX@2|Bacteria,1QUV9@1224|Proteobacteria,43CMN@68525|delta/epsilon subdivisions,2YTEI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_422025_1	709032.Sulku_1405	7.14e-44	161.0	COG2199@1|root,COG3706@2|Bacteria,1NFQH@1224|Proteobacteria,42S2B@68525|delta/epsilon subdivisions,2YPCT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PFAM Type IV pilus assembly PilZ	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1301986_1	709032.Sulku_0131	5.69e-70	227.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,42PK7@68525|delta/epsilon subdivisions,2YMS5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Amidase	-	-	3.5.1.54	ko:K01457	ko00220,ko00791,ko01100,ko01120,map00220,map00791,map01100,map01120	-	R00005	RC02756	ko00000,ko00001,ko01000	-	-	-	Amidase
k59_1360963_2	709032.Sulku_0391	1.57e-118	350.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,42MHD@68525|delta/epsilon subdivisions,2YN9P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
k59_1421682_1	1249480.B649_07400	2.74e-76	241.0	COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,42MCZ@68525|delta/epsilon subdivisions,2YNV4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	HlyD membrane-fusion protein of T1SS	-	-	-	ko:K12542	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	3.A.1.109.4,8.A.1	-	-	HlyD_3
k59_952055_1	1454004.AW11_00426	1.46e-25	99.8	COG0835@1|root,COG0835@2|Bacteria,1N07Q@1224|Proteobacteria,2VU6N@28216|Betaproteobacteria	28216|Betaproteobacteria	NT	PFAM CheW domain protein	pilI	-	-	ko:K02659	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	CheW
k59_952055_2	159087.Daro_3896	5.2e-28	113.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VJBX@28216|Betaproteobacteria,2KU9U@206389|Rhodocyclales	206389|Rhodocyclales	NT	Methyl-accepting chemotaxis protein	pilJ	-	-	ko:K02660	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	MCPsignal,PilJ
k59_542206_1	1132855.KB913035_gene2129	8.51e-67	209.0	COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,2VKE7@28216|Betaproteobacteria,2KKSY@206350|Nitrosomonadales	206350|Nitrosomonadales	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
k59_542206_2	1132855.KB913035_gene2128	2.89e-52	168.0	COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,2VKIN@28216|Betaproteobacteria,2KKY9@206350|Nitrosomonadales	206350|Nitrosomonadales	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
k59_68549_1	159087.Daro_0661	1.74e-120	359.0	COG4191@1|root,COG4191@2|Bacteria,1QU7R@1224|Proteobacteria,2VICU@28216|Betaproteobacteria,2KUXS@206389|Rhodocyclales	206389|Rhodocyclales	T	signal transduction histidine kinase	pilS	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS_8
k59_1185480_2	1291050.JAGE01000001_gene2906	4.35e-46	154.0	COG0270@1|root,COG0270@2|Bacteria,1VE3G@1239|Firmicutes,24NU5@186801|Clostridia	186801|Clostridia	L	DNA (cytosine-5-)-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1539712_1	204773.HEAR1467	1.35e-36	132.0	COG3090@1|root,COG3090@2|Bacteria,1MVKS@1224|Proteobacteria,2VRBP@28216|Betaproteobacteria,474DP@75682|Oxalobacteraceae	28216|Betaproteobacteria	G	TRAP-type C4-dicarboxylate transport system, small permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
k59_659391_1	709032.Sulku_0183	2.46e-53	169.0	2AK71@1|root,31AX6@2|Bacteria,1Q6EC@1224|Proteobacteria,432ZM@68525|delta/epsilon subdivisions,2YSGS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_659391_2	709032.Sulku_0182	3.44e-12	65.1	COG0492@1|root,COG0492@2|Bacteria,1NDW6@1224|Proteobacteria,42MUD@68525|delta/epsilon subdivisions,2YMV2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	pyridine nucleotide-disulfide oxidoreductase	trxB_2	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	FixS,Pyr_redox_3
k59_1246509_1	159087.Daro_4098	3.85e-79	259.0	COG0411@1|root,COG0559@1|root,COG4177@1|root,COG0411@2|Bacteria,COG0559@2|Bacteria,COG4177@2|Bacteria,1MUTY@1224|Proteobacteria,2VH2P@28216|Betaproteobacteria,2KUY7@206389|Rhodocyclales	206389|Rhodocyclales	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
k59_1713818_1	387093.SUN_2453	1.8e-203	573.0	COG3316@1|root,COG3328@1|root,COG3316@2|Bacteria,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,42S30@68525|delta/epsilon subdivisions,2YQEA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
k59_362787_1	1304883.KI912532_gene1780	8.87e-26	99.4	COG2453@1|root,COG2453@2|Bacteria,1NK9T@1224|Proteobacteria,2VYU2@28216|Betaproteobacteria	28216|Betaproteobacteria	T	phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_362787_2	159087.Daro_0975	1.44e-154	444.0	COG0280@1|root,COG2030@1|root,COG0280@2|Bacteria,COG2030@2|Bacteria,1MWPK@1224|Proteobacteria,2WGKC@28216|Betaproteobacteria,2KV8I@206389|Rhodocyclales	206389|Rhodocyclales	CI	Bifunctional enoyl-CoA hydratase phosphate acetyltransferase	pta	-	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydratas,PTA_PTB
k59_1361039_1	395494.Galf_2312	3.76e-38	141.0	COG1450@1|root,COG1450@2|Bacteria,1MVNC@1224|Proteobacteria,2VMT1@28216|Betaproteobacteria,44V3S@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	PFAM type II and III secretion system protein	exeD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N_2
k59_1479756_1	247490.KSU1_D0867	1.54e-17	87.0	COG2203@1|root,COG3829@1|root,COG4251@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria,2J2DQ@203682|Planctomycetes	203682|Planctomycetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,dCache_1
k59_12267_1	709032.Sulku_0319	9.97e-21	99.0	COG1361@1|root,COG1361@2|Bacteria,1QVSF@1224|Proteobacteria,42QQ6@68525|delta/epsilon subdivisions,2YTBA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1655339_1	159087.Daro_0199	3.37e-54	177.0	COG0803@1|root,COG0803@2|Bacteria,1MVW9@1224|Proteobacteria,2VHKN@28216|Betaproteobacteria,2KVG9@206389|Rhodocyclales	206389|Rhodocyclales	P	Belongs to the bacterial solute-binding protein 9 family	-	-	-	ko:K02077	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
k59_1655339_2	1304883.KI912532_gene590	1.93e-83	250.0	COG0488@1|root,COG0488@2|Bacteria,1RJA9@1224|Proteobacteria,2VXIF@28216|Betaproteobacteria,2KX6H@206389|Rhodocyclales	206389|Rhodocyclales	S	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
k59_733087_1	1537917.JU82_11855	3.94e-87	279.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,42MRQ@68525|delta/epsilon subdivisions,2YMJY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1g
k59_917010_1	1249627.D779_0446	2.05e-119	367.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,1WXPB@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_32930_1	411684.HPDFL43_02864	5.66e-25	110.0	COG2304@1|root,COG2911@1|root,COG2931@1|root,COG2304@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,43I5T@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase,Cadherin,DUF4214,HCBP_related,HemolysinCabind,Metallophos
k59_690546_1	1165841.SULAR_07795	6.2e-162	468.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,42MYT@68525|delta/epsilon subdivisions,2YMKP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	phosphate transporter	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
k59_1210593_1	709032.Sulku_1836	9.26e-40	144.0	COG0642@1|root,COG0642@2|Bacteria,1QZ2C@1224|Proteobacteria,42QBR@68525|delta/epsilon subdivisions,2YNQB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_2,sCache_2
k59_1094883_2	1172190.M947_02910	2.82e-24	101.0	COG1168@1|root,COG1168@2|Bacteria,1MY33@1224|Proteobacteria,42M6F@68525|delta/epsilon subdivisions,2YMXE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Aminotransferase, class I	patB	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_917028_1	1163617.SCD_n01422	2.07e-38	145.0	COG0845@1|root,COG0845@2|Bacteria,1MV1R@1224|Proteobacteria,2VHJC@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23
k59_917028_2	1537917.JU82_10685	9.01e-118	348.0	COG0577@1|root,COG0577@2|Bacteria,1MVSU@1224|Proteobacteria,42NKX@68525|delta/epsilon subdivisions,2YNKS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	ABC transporter permease	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_1324987_1	709032.Sulku_0942	1.29e-95	285.0	COG0596@1|root,COG0596@2|Bacteria,1NH3R@1224|Proteobacteria,42R8Q@68525|delta/epsilon subdivisions,2YNWT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
k59_803201_1	232721.Ajs_3714	8.24e-18	82.8	COG2203@1|root,COG2203@2|Bacteria,1PP8V@1224|Proteobacteria,2VKHH@28216|Betaproteobacteria,4ACU3@80864|Comamonadaceae	28216|Betaproteobacteria	T	Pfam:Pyridox_oxidase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	GAF_2,Putative_PNPOx
k59_803201_2	159087.Daro_3700	4.12e-33	123.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2VIIQ@28216|Betaproteobacteria,2KYDV@206389|Rhodocyclales	206389|Rhodocyclales	C	Dehydrogenase E1 component	-	-	1.2.4.1	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
k59_917036_1	85643.Tmz1t_3990	3.23e-99	304.0	COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,2VIFW@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Pfam Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
k59_627877_1	983917.RGE_15030	5.84e-08	60.8	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,2VH64@28216|Betaproteobacteria,1KJFR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	outer membrane cobalamin receptor	btuB	-	-	ko:K02014,ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.3	-	-	Plug,TonB_dep_Rec
k59_1044872_1	159087.Daro_2876	5.8e-105	308.0	COG0688@1|root,COG0688@2|Bacteria,1MVT4@1224|Proteobacteria,2VJCQ@28216|Betaproteobacteria,2KUHW@206389|Rhodocyclales	206389|Rhodocyclales	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
k59_1277603_2	1177179.A11A3_13415	8.51e-28	110.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,1RP0Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	phosphate transporter	pitA	GO:0000041,GO:0003674,GO:0005215,GO:0005315,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006817,GO:0006820,GO:0006829,GO:0008150,GO:0008324,GO:0008509,GO:0015075,GO:0015077,GO:0015078,GO:0015103,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015654,GO:0015672,GO:0015698,GO:0015710,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098656,GO:0098660,GO:0098661,GO:0098662,GO:1902600	-	ko:K03306,ko:K16322	-	-	-	-	ko00000,ko02000	2.A.20,2.A.20.1	-	iECABU_c1320.ECABU_c33930,iECO111_1330.ECO111_4301,iPC815.YPO3967	PHO4
k59_510693_1	709032.Sulku_1920	5.55e-110	324.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,42MGN@68525|delta/epsilon subdivisions,2YNAN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Chorismate mutase prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
k59_690595_1	709032.Sulku_1839	1.16e-93	289.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,42MEM@68525|delta/epsilon subdivisions,2YMWQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
k59_627910_1	748247.AZKH_0020	2e-103	309.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2VHEJ@28216|Betaproteobacteria,2KW0A@206389|Rhodocyclales	206389|Rhodocyclales	E	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.29,3.6.3.30	ko:K02010,ko:K02017,ko:K02052	ko02010,ko02024,map02010,map02024	M00189,M00190,M00193	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10,3.A.1.11,3.A.1.8	-	-	ABC_tran,TOBE_2
k59_447048_1	1168067.JAGP01000001_gene1061	2.81e-64	204.0	COG2917@1|root,COG2917@2|Bacteria,1NWIZ@1224|Proteobacteria,1RQAB@1236|Gammaproteobacteria,460TE@72273|Thiotrichales	72273|Thiotrichales	D	probably involved in intracellular septation	ispZ	-	-	ko:K06190	-	-	-	-	ko00000	-	-	-	IspA
k59_1570402_1	1132855.KB913035_gene878	1.83e-21	85.1	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,2VU4I@28216|Betaproteobacteria,2KN2T@206350|Nitrosomonadales	206350|Nitrosomonadales	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	-	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
k59_1570402_2	666681.M301_1260	1.93e-40	133.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2VVTG@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Cold shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k59_1739559_1	1218075.BAYA01000010_gene3249	9.16e-29	117.0	COG5000@1|root,COG5001@1|root,COG5000@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1K0RA@119060|Burkholderiaceae	28216|Betaproteobacteria	T	GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GAF,GAF_2,GGDEF,HAMP,PAS_4,PAS_9,Response_reg
k59_510724_1	159087.Daro_1022	8.27e-39	132.0	COG4654@1|root,COG4654@2|Bacteria,1N457@1224|Proteobacteria,2VVMH@28216|Betaproteobacteria,2KX9J@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome c	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C
k59_510724_2	159087.Daro_1023	7.49e-73	234.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2VHVH@28216|Betaproteobacteria,2KUHI@206389|Rhodocyclales	206389|Rhodocyclales	G	PQQ-like domain	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ
k59_1621821_1	1565314.OA34_07870	5.06e-51	172.0	COG3842@1|root,COG3842@2|Bacteria,1RC3N@1224|Proteobacteria,42MSG@68525|delta/epsilon subdivisions,2YMX7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	ATP-binding protein	modC	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran
k59_917110_1	159087.Daro_1493	3.55e-52	168.0	COG2878@1|root,COG2878@2|Bacteria,1MUWU@1224|Proteobacteria,2WEHC@28216|Betaproteobacteria,2M040@206389|Rhodocyclales	206389|Rhodocyclales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4
k59_917110_2	159087.Daro_1492	3.31e-63	197.0	COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,2VPVY@28216|Betaproteobacteria,2KY8D@206389|Rhodocyclales	206389|Rhodocyclales	U	Part of a membrane complex involved in electron transport	-	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
k59_1739574_1	1249480.B649_01180	9.02e-134	385.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,42MMX@68525|delta/epsilon subdivisions,2YMNX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
k59_1157987_1	1165841.SULAR_07490	3.1e-39	139.0	COG0799@1|root,COG1057@1|root,COG0799@2|Bacteria,COG1057@2|Bacteria,1NG4J@1224|Proteobacteria,42P0F@68525|delta/epsilon subdivisions,2YMQR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like,RsfS
k59_1157987_2	1165841.SULAR_07485	2.11e-95	287.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,42N9Q@68525|delta/epsilon subdivisions,2YMUH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k59_1739598_1	511.JT27_05540	1.82e-60	200.0	2AJB7@1|root,319WD@2|Bacteria,1R527@1224|Proteobacteria	1224|Proteobacteria	S	FRG	-	-	-	-	-	-	-	-	-	-	-	-	DUF3387,FRG
k59_981167_1	1249480.B649_02710	1.37e-127	367.0	COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,42NWH@68525|delta/epsilon subdivisions,2YQPR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
k59_214212_1	497321.C664_19566	2.38e-12	65.9	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,2VIGA@28216|Betaproteobacteria,2KUKY@206389|Rhodocyclales	206389|Rhodocyclales	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
k59_214212_2	159087.Daro_2985	1.75e-112	332.0	COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,2VID7@28216|Betaproteobacteria,2KUBR@206389|Rhodocyclales	206389|Rhodocyclales	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
k59_1863763_1	1249480.B649_05790	5.18e-69	210.0	2AJSH@1|root,31AEU@2|Bacteria,1Q5GG@1224|Proteobacteria,42QZH@68525|delta/epsilon subdivisions,2YP33@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1863763_2	1249480.B649_05795	1.39e-49	167.0	COG0665@1|root,COG0665@2|Bacteria,1Q0BQ@1224|Proteobacteria,42RXA@68525|delta/epsilon subdivisions,2YP66@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	COGs COG0665 Glycine D-amino acid oxidase (deaminating)	-	-	2.1.1.61	ko:K15461	-	-	R00601,R08702	RC00003,RC00053,RC00060,RC01483	ko00000,ko01000,ko03016	-	-	-	DAO
k59_1680374_1	1278307.KB906969_gene2267	7.9e-08	57.8	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,1RN5T@1236|Gammaproteobacteria,2QHXW@267894|Psychromonadaceae	1236|Gammaproteobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008773,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019538,GO:0019752,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0070569,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,GlnD_UR_UTase,HD,NTP_transf_2
k59_1680374_2	2340.JV46_18780	7.36e-36	126.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	gloA	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase
k59_158475_1	426114.THI_2039	1.87e-132	399.0	COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,2VJJW@28216|Betaproteobacteria,1KK32@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Von Willebrand factor type A	cbbO2	-	-	ko:K02448	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	VWA,VWA_2
k59_510779_1	709032.Sulku_1759	3.95e-48	156.0	COG1959@1|root,COG1959@2|Bacteria,1MZ1C@1224|Proteobacteria,42SJM@68525|delta/epsilon subdivisions,2YPJG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
k59_1277695_1	1537917.JU82_09195	1.29e-185	534.0	COG0046@1|root,COG0046@2|Bacteria,1MYN4@1224|Proteobacteria,42M08@68525|delta/epsilon subdivisions,2YMHZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
k59_733227_1	709032.Sulku_0179	1.06e-104	304.0	COG0622@1|root,COG0622@2|Bacteria,1NPH4@1224|Proteobacteria,42TB8@68525|delta/epsilon subdivisions,2YPHV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Phosphoesterase	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
k59_385836_2	1249480.B649_09080	5.14e-69	213.0	COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,42NRX@68525|delta/epsilon subdivisions,2YMSK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
k59_1739661_1	1537917.JU82_00115	5.35e-97	288.0	COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,42M4G@68525|delta/epsilon subdivisions,2YN1Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
k59_1570505_1	1249480.B649_01625	7.82e-100	308.0	COG2203@1|root,COG2206@1|root,COG3829@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,COG3829@2|Bacteria,1RAQS@1224|Proteobacteria,42QQI@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	PFAM Metal-dependent phosphohydrolase, HD	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,GAF_2,HD,HD_5,PAS,PAS_4,PAS_8,PAS_9,Response_reg,sCache_2
k59_33112_1	1304883.KI912532_gene329	5.81e-86	263.0	COG3825@1|root,COG3825@2|Bacteria,1MUAJ@1224|Proteobacteria,2VJ99@28216|Betaproteobacteria,2KUDU@206389|Rhodocyclales	206389|Rhodocyclales	S	Von Willebrand factor A	-	-	-	ko:K09989	-	-	-	-	ko00000	-	-	-	VWA_CoxE
k59_33112_2	1040983.AXAE01000015_gene1235	7.25e-07	49.7	COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,2TRI8@28211|Alphaproteobacteria,43H2I@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	ATPase (AAA	MA20_01295	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
k59_158507_1	1537917.JU82_03100	2.29e-68	230.0	COG4581@1|root,COG4581@2|Bacteria,1MVD6@1224|Proteobacteria,42PR3@68525|delta/epsilon subdivisions,2YN2Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Mitochondrial degradasome RNA helicase subunit C terminal	-	-	3.6.4.13	ko:K17675	-	-	-	-	ko00000,ko01000,ko03029	-	-	-	Helicase_C,SUV3_C
k59_1621904_1	159087.Daro_3968	4.48e-49	162.0	COG1773@1|root,COG1773@2|Bacteria,1N813@1224|Proteobacteria,2VVKP@28216|Betaproteobacteria,2KWW9@206389|Rhodocyclales	206389|Rhodocyclales	C	[NiFe]-hydrogenase assembly, chaperone, HybE	-	-	-	-	-	-	-	-	-	-	-	-	NiFe-hyd_HybE
k59_1387970_1	159087.Daro_2275	6.99e-30	112.0	COG3350@1|root,COG3350@2|Bacteria,1Q0ZJ@1224|Proteobacteria,2W5XC@28216|Betaproteobacteria	28216|Betaproteobacteria	S	YHS domain	-	-	-	-	-	-	-	-	-	-	-	-	YHS
k59_1570544_2	1249480.B649_09440	2.17e-76	236.0	COG0242@1|root,COG0242@2|Bacteria,1QNIH@1224|Proteobacteria,42TAD@68525|delta/epsilon subdivisions,2YPKH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	COG0242 N-formylmethionyl-tRNA deformylase	-	-	-	-	-	-	-	-	-	-	-	-	Pep_deformylase
k59_803375_1	1165841.SULAR_06303	1.11e-152	444.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,42MB1@68525|delta/epsilon subdivisions,2YMVC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
k59_572840_1	1249480.B649_03510	1e-128	395.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,42MGK@68525|delta/epsilon subdivisions,2YMHU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_1621927_1	1158146.KB907128_gene1840	4.57e-44	155.0	COG0614@1|root,COG0614@2|Bacteria	2|Bacteria	P	abc-type fe3 -hydroxamate transport system, periplasmic component	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
k59_1621927_2	1122197.ATWI01000010_gene973	2.61e-62	196.0	COG0778@1|root,COG0778@2|Bacteria,1MZN8@1224|Proteobacteria,1RPVA@1236|Gammaproteobacteria,46944@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	COG0778 Nitroreductase	bluB	-	1.13.11.79	ko:K04719	ko00740,ko01100,map00740,map01100	-	R09083	RC00435,RC02413	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
k59_1277760_1	709032.Sulku_2074	4.86e-38	130.0	COG0811@1|root,COG0811@2|Bacteria,1RK2P@1224|Proteobacteria,42TPV@68525|delta/epsilon subdivisions,2YPGE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Biopolymer transporter ExbB	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k59_1277760_2	1249480.B649_09790	9.47e-88	265.0	COG0642@1|root,COG0642@2|Bacteria,1QZ1Z@1224|Proteobacteria,42SN7@68525|delta/epsilon subdivisions,2YPK7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
k59_1325224_1	1249480.B649_09180	2.02e-36	133.0	COG0795@1|root,COG0795@2|Bacteria,1PXEK@1224|Proteobacteria,42MVG@68525|delta/epsilon subdivisions,2YN6F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	permease	-	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_1507078_1	1123514.KB905899_gene1375	1.03e-111	332.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,45ZQ6@72273|Thiotrichales	72273|Thiotrichales	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_1743484_2	1537917.JU82_02785	2.28e-47	159.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,42N0M@68525|delta/epsilon subdivisions,2YT9X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules	xerH	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_1683010_1	1256908.HMPREF0373_00503	1.21e-13	75.9	COG0642@1|root,COG0784@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,1TSDF@1239|Firmicutes,250SJ@186801|Clostridia,25ZJN@186806|Eubacteriaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
k59_984881_1	1537917.JU82_09340	4.06e-36	127.0	2A1M6@1|root,30PVA@2|Bacteria,1QTJ9@1224|Proteobacteria,42VDW@68525|delta/epsilon subdivisions,2YQIZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
k59_388251_1	387093.SUN_1391	5.78e-14	77.4	COG5002@1|root,COG5002@2|Bacteria,1QZ29@1224|Proteobacteria,43CEG@68525|delta/epsilon subdivisions,2YTC2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_1799360_1	1165841.SULAR_03183	1.97e-61	203.0	COG1757@1|root,COG1757@2|Bacteria,1MY5C@1224|Proteobacteria,42P0P@68525|delta/epsilon subdivisions,2YN3S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Na H antiporter	nhaC	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
k59_1455814_2	1144343.PMI41_03345	0.000882	41.6	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,43NY2@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	Q	PFAM Hemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
k59_693958_1	159087.Daro_2991	2.52e-169	482.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2VHJP@28216|Betaproteobacteria,2KV2N@206389|Rhodocyclales	206389|Rhodocyclales	G	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	ko:K11690	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctM
k59_513431_1	477184.KYC_19364	9.74e-88	285.0	COG3299@1|root,COG3299@2|Bacteria,1P3E0@1224|Proteobacteria,2VKDQ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J,PA14
k59_217438_1	1249480.B649_09975	1.77e-150	440.0	COG0028@1|root,COG0028@2|Bacteria,1MYUS@1224|Proteobacteria,42QE8@68525|delta/epsilon subdivisions,2YNKA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_1280748_1	159087.Daro_2828	2.69e-77	237.0	COG0697@1|root,COG0697@2|Bacteria,1MWSU@1224|Proteobacteria,2VHP3@28216|Betaproteobacteria,2KUCN@206389|Rhodocyclales	206389|Rhodocyclales	EG	Solute carrier family 35	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_1280748_2	1304883.KI912532_gene2785	8.9e-32	124.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,2VHSK@28216|Betaproteobacteria,2KV96@206389|Rhodocyclales	206389|Rhodocyclales	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
k59_1507191_1	1249480.B649_07905	6.31e-50	164.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,42P96@68525|delta/epsilon subdivisions,2YTJM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	abc transporter atp-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_1507191_2	326298.Suden_2041	1.53e-58	194.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42NVA@68525|delta/epsilon subdivisions,2YMYW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
k59_93114_1	1449345.JHWC01000005_gene1149	6.84e-56	193.0	COG2604@1|root,COG2604@2|Bacteria,1R4P0@1224|Proteobacteria,42NB8@68525|delta/epsilon subdivisions,2YMMI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	hmm pf01973	pseE	-	-	-	-	-	-	-	-	-	-	-	MAF_flag10
k59_735928_1	395494.Galf_0628	1.6e-92	278.0	COG1639@1|root,COG1639@2|Bacteria	2|Bacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_806254_1	563040.Saut_1428	1.4e-57	193.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,42MAP@68525|delta/epsilon subdivisions,2YNFF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	transporter	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
k59_160965_1	929558.SMGD1_1719	1.27e-05	54.3	COG0745@1|root,COG0745@2|Bacteria,1QXJT@1224|Proteobacteria,42V47@68525|delta/epsilon subdivisions,2YQ8S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	RESPONSE REGULATOR receiver	-	-	-	ko:K07288	-	-	-	-	ko00000	-	-	-	-
k59_160965_2	387093.SUN_2210	6.82e-109	317.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,42R4H@68525|delta/epsilon subdivisions,2YNWA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0321	Guanylate_kin
k59_694043_1	572480.Arnit_2737	1.12e-29	121.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,ABC_sub_bind,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,SBP_bac_3,dCache_2,dCache_3
k59_1213958_1	653733.Selin_1142	6.08e-39	150.0	COG2202@1|root,COG2203@1|root,COG5000@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG5000@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.1.1.80,2.7.13.3,2.7.8.41,3.1.1.61	ko:K07716,ko:K08744,ko:K13598,ko:K13924	ko00564,ko01100,ko02020,ko02030,ko04112,map00564,map01100,map02020,map02030,map04112	M00498,M00506,M00511	R02030	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg,SpoIIE
k59_1160830_1	387093.SUN_2046	1.87e-67	225.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,42M09@68525|delta/epsilon subdivisions,2YMWR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
k59_450055_1	709032.Sulku_0482	1.62e-36	131.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,42MZR@68525|delta/epsilon subdivisions,2YN0Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
k59_450055_2	929558.SMGD1_2198	2.25e-24	99.8	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,42P56@68525|delta/epsilon subdivisions,2YNV5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
k59_273051_2	709032.Sulku_1760	9.47e-56	192.0	COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,42NB2@68525|delta/epsilon subdivisions,2YMVN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
k59_1743692_1	709032.Sulku_2204	2.66e-108	325.0	COG1757@1|root,COG1757@2|Bacteria,1MY5C@1224|Proteobacteria,42P0P@68525|delta/epsilon subdivisions,2YN3S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Na H antiporter	nhaC	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
k59_1160860_1	1123368.AUIS01000024_gene943	5.34e-64	220.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,2NCGG@225057|Acidithiobacillales	225057|Acidithiobacillales	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1683170_1	387093.SUN_0609	1.23e-48	159.0	COG3663@1|root,COG3663@2|Bacteria,1REPV@1224|Proteobacteria,42SIJ@68525|delta/epsilon subdivisions,2YPP8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	G T U mismatch-specific DNA glycosylase	mug	-	-	-	-	-	-	-	-	-	-	-	UDG
k59_1683170_2	387093.SUN_0610	5.54e-81	247.0	COG0639@1|root,COG0639@2|Bacteria,1MV10@1224|Proteobacteria,42T30@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP	apaH	GO:0003674,GO:0003824,GO:0004551,GO:0004721,GO:0006139,GO:0006464,GO:0006470,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008138,GO:0008150,GO:0008152,GO:0008796,GO:0008803,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0015949,GO:0016311,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0019538,GO:0034641,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0140096,GO:1901360,GO:1901564	3.6.1.41	ko:K01525	ko00230,map00230	-	R00125	RC00002	ko00000,ko00001,ko01000	-	-	iECIAI39_1322.ECIAI39_0052,iEcSMS35_1347.EcSMS35_0053,iSDY_1059.SDY_0074	Metallophos
k59_1455990_1	90814.KL370891_gene1675	1.34e-111	336.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,1RMWS@1236|Gammaproteobacteria,46009@72273|Thiotrichales	72273|Thiotrichales	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
k59_985108_1	1165841.SULAR_00445	8.55e-65	209.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,42NJ0@68525|delta/epsilon subdivisions,2YM9A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
k59_1706591_1	159087.Daro_3751	1.76e-74	243.0	COG1656@1|root,COG1656@2|Bacteria,1QWEF@1224|Proteobacteria,2WGZK@28216|Betaproteobacteria,2KW1W@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of unknown function (DUF4178)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4178
k59_591186_1	1454004.AW11_01529	1.86e-72	233.0	COG0845@1|root,COG5569@1|root,COG0845@2|Bacteria,COG5569@2|Bacteria,1MVAS@1224|Proteobacteria,2VJXV@28216|Betaproteobacteria,1KQYK@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	M	HlyD family secretion protein	cusB	-	-	ko:K07798,ko:K15727	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1,8.A.1.2.1	-	-	CusF_Ec,HlyD_D23
k59_1706593_1	1132855.KB913035_gene636	9.12e-110	325.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,2VGZP@28216|Betaproteobacteria,2KKH3@206350|Nitrosomonadales	206350|Nitrosomonadales	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
k59_1589426_1	709032.Sulku_1956	1.36e-63	212.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42N03@68525|delta/epsilon subdivisions,2YNMG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	PFAM Methyl-accepting chemotaxis protein (MCP) signaling domain	-	-	-	ko:K03406,ko:K05875	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,MCPsignal
k59_1002490_1	709032.Sulku_0252	1.22e-11	63.9	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,42MVI@68525|delta/epsilon subdivisions,2YMGY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	aldo keto reductase	tas	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_1002490_2	1537917.JU82_10825	2.19e-72	222.0	29BMV@1|root,2ZYK6@2|Bacteria,1Q9EE@1224|Proteobacteria,42VEN@68525|delta/epsilon subdivisions,2YQKT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1825097_1	1249480.B649_03270	1.39e-11	70.5	COG2199@1|root,COG3706@2|Bacteria,1NECV@1224|Proteobacteria,42PZK@68525|delta/epsilon subdivisions,2YT9R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_5727_1	1537917.JU82_01240	1.33e-97	303.0	COG0204@1|root,COG0477@1|root,COG0204@2|Bacteria,COG2814@2|Bacteria,1MWDY@1224|Proteobacteria,43BJD@68525|delta/epsilon subdivisions,2YNEB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	2-acylglycerophosphoethanolamine acyltransferase	aas	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
k59_884773_1	1249480.B649_10755	1.35e-77	246.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,42MA7@68525|delta/epsilon subdivisions,2YMTP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
k59_884773_2	1249480.B649_10760	1.24e-28	110.0	COG0535@1|root,COG0535@2|Bacteria,1N2I6@1224|Proteobacteria,42P9K@68525|delta/epsilon subdivisions,2YNK6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
k59_5729_1	580332.Slit_1638	1.87e-07	52.4	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,2VIBP@28216|Betaproteobacteria,44VEA@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
k59_5729_2	765913.ThidrDRAFT_3526	3.58e-50	166.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,1RQ4B@1236|Gammaproteobacteria,1WYG2@135613|Chromatiales	135613|Chromatiales	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
k59_1060529_1	1442598.JABW01000002_gene1667	2.6e-67	219.0	COG3547@1|root,COG3547@2|Bacteria,1NCHY@1224|Proteobacteria,42TM4@68525|delta/epsilon subdivisions,2YNU9@29547|Epsilonproteobacteria	68525|delta/epsilon subdivisions	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_707989_1	1537917.JU82_02205	1.16e-97	287.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,42NBY@68525|delta/epsilon subdivisions,2YMSY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Co-chaperone-curved DNA binding protein A	cbpA	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
k59_474265_1	709032.Sulku_0499	4.62e-91	271.0	COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,42P8R@68525|delta/epsilon subdivisions,2YM7K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
k59_415130_1	1132855.KB913035_gene839	2.94e-138	403.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,2VJ07@28216|Betaproteobacteria,2KKPI@206350|Nitrosomonadales	206350|Nitrosomonadales	H	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
k59_884817_1	709032.Sulku_1274	1.67e-119	352.0	COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,42N4P@68525|delta/epsilon subdivisions,2YMDF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
k59_239040_2	1172190.M947_05945	1.02e-20	84.0	2AIVC@1|root,32MS0@2|Bacteria,1Q3D2@1224|Proteobacteria,42X4G@68525|delta/epsilon subdivisions,2YQTS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Family of unknown function (DUF4006)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4006
k59_239040_3	1537917.JU82_02095	7.72e-118	342.0	2AI9D@1|root,318Q0@2|Bacteria,1Q0R3@1224|Proteobacteria,42SDN@68525|delta/epsilon subdivisions,2YP0E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1237756_1	1385935.N836_16225	2.35e-70	217.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_12,Methyltransf_23,Methyltransf_25,Methyltransf_31
k59_1647954_1	1500306.JQLA01000012_gene2800	2.83e-05	52.8	COG1807@1|root,COG1807@2|Bacteria,1P6JE@1224|Proteobacteria,2TV39@28211|Alphaproteobacteria,4BDNZ@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,GtrA,PMT_2
k59_1765369_1	709032.Sulku_2305	2.93e-100	295.0	COG1385@1|root,COG1385@2|Bacteria,1QDSD@1224|Proteobacteria,42S1W@68525|delta/epsilon subdivisions,2YP9M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
k59_1295595_2	1537917.JU82_04690	4.38e-61	194.0	COG2204@1|root,COG2204@2|Bacteria,1QASN@1224|Proteobacteria,42RV2@68525|delta/epsilon subdivisions,2YP76@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activ_2,Sigma54_activat
k59_1706662_1	279714.FuraDRAFT_2086	3.43e-159	450.0	COG3384@1|root,COG3384@2|Bacteria,1MWNC@1224|Proteobacteria,2VK29@28216|Betaproteobacteria,2KSNQ@206351|Neisseriales	206351|Neisseriales	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	LigB
k59_1825177_1	1249480.B649_05850	1.74e-10	58.5	COG1763@1|root,COG1763@2|Bacteria,1RD3Q@1224|Proteobacteria,42RZK@68525|delta/epsilon subdivisions,2YPCQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	molybdopterin-guanine dinucleotide biosynthesis protein	mobB	-	-	ko:K03753	-	-	-	-	ko00000	-	-	-	MobB
k59_1825177_2	1249480.B649_05855	1.31e-95	284.0	COG0158@1|root,COG0158@2|Bacteria,1MW0E@1224|Proteobacteria,42NRA@68525|delta/epsilon subdivisions,2YMJC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1	fbp	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
k59_826546_2	1304883.KI912532_gene617	4.67e-60	187.0	COG1576@1|root,COG1576@2|Bacteria,1R9Z2@1224|Proteobacteria,2VQ2M@28216|Betaproteobacteria,2KWIS@206389|Rhodocyclales	206389|Rhodocyclales	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
k59_239053_1	123214.PERMA_1653	4.88e-54	192.0	COG5001@1|root,COG5001@2|Bacteria	2|Bacteria	T	cyclic-guanylate-specific phosphodiesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	EAL,FIST,FIST_C,GGDEF
k59_62709_1	159087.Daro_3934	9.82e-168	469.0	COG3176@1|root,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,2VH4B@28216|Betaproteobacteria,2KU7J@206389|Rhodocyclales	206389|Rhodocyclales	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5
k59_1237785_1	32057.KB217478_gene597	9.48e-11	62.8	2DBXS@1|root,2ZBR1@2|Bacteria,1G9A8@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_651155_2	1537917.JU82_11290	7.29e-179	505.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,42MHK@68525|delta/epsilon subdivisions,2YMEV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
k59_474306_1	553178.CAPGI0001_2104	3.02e-05	45.4	COG0463@1|root,COG0463@2|Bacteria,4NK1T@976|Bacteroidetes,1HZ1Q@117743|Flavobacteriia,1ETFH@1016|Capnocytophaga	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_474306_2	946483.Cenrod_0502	6.37e-19	90.9	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2VHBY@28216|Betaproteobacteria,4A9JC@80864|Comamonadaceae	28216|Betaproteobacteria	E	Asparagine synthase, glutamine-hydrolyzing	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_943987_1	1249480.B649_07410	9.95e-122	361.0	COG1538@1|root,COG1538@2|Bacteria,1MYX2@1224|Proteobacteria,42MHZ@68525|delta/epsilon subdivisions,2YNGC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	Outer membrane efflux protein	-	-	-	ko:K12543	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	1.B.17,3.A.1.109.4	-	-	OEP,OmpA,TSP_3
k59_1706691_1	159087.Daro_0215	2.89e-35	124.0	COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,2VRDN@28216|Betaproteobacteria,2KWHZ@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
k59_1706691_2	159087.Daro_0214	5.18e-27	108.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,2VHY4@28216|Betaproteobacteria,2KUHK@206389|Rhodocyclales	206389|Rhodocyclales	U	Type 4 fimbrial biogenesis protein	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
k59_356210_1	1165841.SULAR_01988	4.76e-102	304.0	COG0167@1|root,COG0167@2|Bacteria,1MXER@1224|Proteobacteria,42QNP@68525|delta/epsilon subdivisions,2YR5C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
k59_1002617_1	1537917.JU82_01455	3.35e-76	239.0	COG2206@1|root,COG2206@2|Bacteria,1R53C@1224|Proteobacteria,42R7P@68525|delta/epsilon subdivisions,2YPRS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
k59_826582_1	1249480.B649_03115	5.52e-125	374.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42YH8@68525|delta/epsilon subdivisions,2YRAU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
k59_766683_1	1249480.B649_10415	1.16e-59	193.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,42N1I@68525|delta/epsilon subdivisions,2YMA0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome	ccpA	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
k59_651199_1	1304883.KI912532_gene495	1.27e-57	181.0	COG0346@1|root,COG0346@2|Bacteria,1RA9H@1224|Proteobacteria,2VQ0D@28216|Betaproteobacteria,2KVY3@206389|Rhodocyclales	206389|Rhodocyclales	E	Lactoylglutathione lyase	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase_4
k59_651199_2	977880.RALTA_A2459	2.01e-43	149.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,2VHEW@28216|Betaproteobacteria,1K2AG@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
k59_1237836_1	159087.Daro_0960	2.34e-81	259.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,2VJ2J@28216|Betaproteobacteria,2KUJW@206389|Rhodocyclales	206389|Rhodocyclales	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
k59_1237836_2	159087.Daro_0961	5.93e-42	149.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,2VIAX@28216|Betaproteobacteria,2KVU3@206389|Rhodocyclales	206389|Rhodocyclales	C	COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M)	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
k59_179670_3	1304883.KI912532_gene1150	1.49e-37	134.0	COG2974@1|root,COG2974@2|Bacteria,1MXPR@1224|Proteobacteria,2VHD8@28216|Betaproteobacteria,2KVYJ@206389|Rhodocyclales	206389|Rhodocyclales	L	May be involved in recombination	rdgC	-	-	ko:K03554	-	-	-	-	ko00000,ko03400	-	-	-	RdgC
k59_768082_1	1288494.EBAPG3_25110	1.41e-38	132.0	COG0517@1|root,COG0517@2|Bacteria,1QTXQ@1224|Proteobacteria,2VWDB@28216|Betaproteobacteria,3734T@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
k59_1708252_1	387093.SUN_0600	1.66e-87	271.0	COG1418@1|root,COG1418@2|Bacteria,1P7YA@1224|Proteobacteria,42KZ8@68525|delta/epsilon subdivisions,2YMQS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
k59_1708252_2	1249480.B649_03055	1.53e-62	196.0	COG0652@1|root,COG0652@2|Bacteria,1RENS@1224|Proteobacteria,42RIB@68525|delta/epsilon subdivisions,2YPAC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Pro_isomerase
k59_828299_1	159087.Daro_3734	6.53e-103	314.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,PAS_3,PAS_4,PAS_9,dCache_1
k59_1533331_1	1537917.JU82_00175	6.3e-39	137.0	COG0642@1|root,COG2205@2|Bacteria,1RK1D@1224|Proteobacteria,42R91@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_1533331_2	709032.Sulku_1950	5.2e-51	164.0	COG1871@1|root,COG1871@2|Bacteria,1RDDB@1224|Proteobacteria,43AIB@68525|delta/epsilon subdivisions,2YSY8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	-	-	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
k59_1591128_1	1249480.B649_10400	1.83e-114	350.0	COG0715@1|root,COG0834@1|root,COG2199@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42UTN@68525|delta/epsilon subdivisions,2YTHQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EPT	NMT1/THI5 like	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	GGDEF,NMT1,SBP_bac_3
k59_1533350_1	159087.Daro_3198	9.42e-29	109.0	COG0664@1|root,COG0664@2|Bacteria,1R5P7@1224|Proteobacteria,2VIQI@28216|Betaproteobacteria,2KVHP@206389|Rhodocyclales	206389|Rhodocyclales	K	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
k59_1708273_1	1122164.JHWF01000011_gene2474	3.73e-09	58.5	COG0037@1|root,COG0037@2|Bacteria,1NKHX@1224|Proteobacteria,1SZDS@1236|Gammaproteobacteria,1JGN0@118969|Legionellales	118969|Legionellales	D	ATPase of the PP-loop superfamily implicated in cell cycle control	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1708273_2	1150621.SMUL_2462	5.9e-36	129.0	COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,42QX8@68525|delta/epsilon subdivisions,2YP1G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
k59_945779_1	1304883.KI912532_gene2125	1.25e-101	300.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,2VH6I@28216|Betaproteobacteria,2KUN1@206389|Rhodocyclales	206389|Rhodocyclales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
k59_7536_2	709032.Sulku_0255	3.66e-100	300.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42N1P@68525|delta/epsilon subdivisions,2YP3M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	COG0436 Aspartate tyrosine aromatic aminotransferase	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_416778_1	159087.Daro_4137	3.19e-49	163.0	COG2267@1|root,COG2267@2|Bacteria,1QVBZ@1224|Proteobacteria,2VNI1@28216|Betaproteobacteria,2KUFT@206389|Rhodocyclales	206389|Rhodocyclales	I	Alpha beta hydrolase	-	-	1.11.1.10	ko:K00433	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_6
k59_416778_2	159087.Daro_4136	5.7e-34	117.0	2AF9M@1|root,3158S@2|Bacteria,1PVA1@1224|Proteobacteria,2WB6F@28216|Betaproteobacteria,2KXN8@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
k59_416778_3	159087.Daro_4135	2.48e-23	97.8	COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,2VIN5@28216|Betaproteobacteria,2KUCQ@206389|Rhodocyclales	206389|Rhodocyclales	J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases	cca	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
k59_1297083_1	1165841.SULAR_07685	2.35e-86	261.0	COG0648@1|root,COG0648@2|Bacteria,1MX4Y@1224|Proteobacteria,42MYE@68525|delta/epsilon subdivisions,2YMF4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
k59_1004651_1	159087.Daro_3617	1.53e-97	290.0	COG4249@1|root,COG4249@2|Bacteria,1RC3Z@1224|Proteobacteria,2VQVC@28216|Betaproteobacteria,2KXTP@206389|Rhodocyclales	206389|Rhodocyclales	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
k59_1473524_1	159087.Daro_1212	3.36e-57	186.0	COG2025@1|root,COG2025@2|Bacteria,1MUFI@1224|Proteobacteria,2VI6W@28216|Betaproteobacteria,2KUDQ@206389|Rhodocyclales	206389|Rhodocyclales	C	Electron transfer flavoprotein alpha subunit	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
k59_1473524_2	1121004.ATVC01000006_gene1307	1.29e-11	63.2	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,2VHXJ@28216|Betaproteobacteria,2KQFU@206351|Neisseriales	206351|Neisseriales	C	electron transfer flavoprotein	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
k59_1767011_1	1122139.KB907874_gene2659	3.63e-13	69.7	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,1RM7Q@1236|Gammaproteobacteria,1XHU3@135619|Oceanospirillales	135619|Oceanospirillales	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k59_1767011_2	498211.CJA_0651	2.01e-58	197.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,1RNQ8@1236|Gammaproteobacteria,1FGG5@10|Cellvibrio	1236|Gammaproteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008883,GO:0009058,GO:0009064,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	iECNA114_1301.ECNA114_1375,iECSF_1327.ECSF_1186,iUTI89_1310.UTI89_C1404	GlutR_N,GlutR_dimer,Shikimate_DH
k59_1533391_1	709032.Sulku_2327	8.44e-46	160.0	COG1070@1|root,COG1070@2|Bacteria,1MWS5@1224|Proteobacteria,43CSA@68525|delta/epsilon subdivisions,2YNV8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	COG1070 Sugar (pentulose and hexulose)	-	-	2.7.1.189	ko:K11216	ko02024,map02024	-	R11183	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
k59_1533391_2	1249480.B649_11020	8.24e-62	189.0	COG1359@1|root,COG1359@2|Bacteria,1NGPW@1224|Proteobacteria,42UUW@68525|delta/epsilon subdivisions,2YQ5Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
k59_593041_1	317936.Nos7107_2342	6.43e-35	126.0	COG0748@1|root,COG0748@2|Bacteria,1G7II@1117|Cyanobacteria	1117|Cyanobacteria	P	Heme iron utilization protein	-	-	-	ko:K07226	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
k59_593041_2	1165841.SULAR_09509	1.17e-53	171.0	COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,42SJ8@68525|delta/epsilon subdivisions,2YNWU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
k59_593049_1	159087.Daro_0706	5.25e-65	217.0	COG1538@1|root,COG4319@1|root,COG1538@2|Bacteria,COG4319@2|Bacteria,1MYX2@1224|Proteobacteria,2VKDN@28216|Betaproteobacteria,2KUPB@206389|Rhodocyclales	206389|Rhodocyclales	MU	COG1538 Outer membrane protein	-	-	-	ko:K12543	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	1.B.17,3.A.1.109.4	-	-	DUF4440,OEP
k59_240705_1	1127692.HMPREF9075_02000	2.14e-11	63.9	COG0399@1|root,COG0399@2|Bacteria,4NFAI@976|Bacteroidetes,1HX99@117743|Flavobacteriia,1ERYW@1016|Capnocytophaga	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
k59_240705_2	1307761.L21SP2_3150	4.38e-39	137.0	COG0110@1|root,COG0110@2|Bacteria,2JAQ3@203691|Spirochaetes	203691|Spirochaetes	S	maltose O-acetyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_945828_1	1304883.KI912532_gene1871	2.61e-90	276.0	COG3490@1|root,COG3490@2|Bacteria,1NNS5@1224|Proteobacteria,2VK39@28216|Betaproteobacteria,2KY8J@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF1513)	-	-	-	ko:K09947	-	-	-	-	ko00000	-	-	-	DUF1513
k59_7586_1	1537917.JU82_01910	6.12e-95	285.0	2A4YW@1|root,30TKN@2|Bacteria,1PDH4@1224|Proteobacteria,42SHS@68525|delta/epsilon subdivisions,2YPG5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_123692_1	1323663.AROI01000002_gene1148	3.62e-38	139.0	COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,1RNCK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k59_123692_2	999141.GME_14510	6.27e-66	214.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,1RN7Z@1236|Gammaproteobacteria,1XHSK@135619|Oceanospirillales	135619|Oceanospirillales	J	SAM-dependent	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
k59_1062130_1	1165841.SULAR_03502	1.32e-44	157.0	COG0526@1|root,COG0526@2|Bacteria,1R0XY@1224|Proteobacteria,43D37@68525|delta/epsilon subdivisions,2YTFX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CO	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
k59_1473565_1	159087.Daro_1609	5.75e-62	195.0	COG1028@1|root,COG1028@2|Bacteria,1MUEV@1224|Proteobacteria,2VH8R@28216|Betaproteobacteria,2KVKX@206389|Rhodocyclales	206389|Rhodocyclales	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	1.1.1.36	ko:K00023	ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200	M00373	R01779,R01977	RC00103,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short,adh_short_C2
k59_1473565_2	159087.Daro_1610	4.45e-67	208.0	COG1028@1|root,COG1028@2|Bacteria,1MUEV@1224|Proteobacteria,2VH8R@28216|Betaproteobacteria,2KVXS@206389|Rhodocyclales	206389|Rhodocyclales	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	1.1.1.36	ko:K00023	ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200	M00373	R01779,R01977	RC00103,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short,adh_short_C2
k59_1415163_1	1165841.SULAR_09699	3.65e-86	265.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,42NNS@68525|delta/epsilon subdivisions,2YMQW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
k59_1533431_1	159087.Daro_0683	6.07e-154	443.0	COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,2VPFR@28216|Betaproteobacteria,2KXRJ@206389|Rhodocyclales	206389|Rhodocyclales	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
k59_1708350_1	1145276.T479_05650	1e-07	55.5	COG2199@1|root,COG2199@2|Bacteria,1TR65@1239|Firmicutes,4HBA6@91061|Bacilli,3IVYA@400634|Lysinibacillus	91061|Bacilli	T	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_1
k59_945854_1	946483.Cenrod_2399	3.01e-44	162.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,4AD7J@80864|Comamonadaceae	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	CZB,EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
k59_945854_2	697282.Mettu_1938	2.2e-29	109.0	COG2703@1|root,COG2703@2|Bacteria,1PGPP@1224|Proteobacteria,1RX1T@1236|Gammaproteobacteria,1XGPW@135618|Methylococcales	135618|Methylococcales	P	PFAM Haemerythrin HHE cation-binding motif	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
k59_1415174_1	1000565.METUNv1_03558	3.37e-81	268.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2VHYQ@28216|Betaproteobacteria,2KUFA@206389|Rhodocyclales	206389|Rhodocyclales	H	methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
k59_1415177_2	1537917.JU82_11815	8.42e-24	96.3	COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,42R60@68525|delta/epsilon subdivisions,2YNZM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_1439696_2	1249480.B649_03820	8.89e-55	183.0	COG2308@1|root,COG2308@2|Bacteria,1MUAD@1224|Proteobacteria,42MA8@68525|delta/epsilon subdivisions,2YNA8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
k59_1786209_2	326298.Suden_2012	4.92e-05	49.7	COG0845@1|root,COG0845@2|Bacteria,1QMYR@1224|Proteobacteria,42WWX@68525|delta/epsilon subdivisions,2YR01@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	RND family efflux transporter, MFP subunit	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
k59_1493143_1	709032.Sulku_0409	1.01e-114	347.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1NQKX@1224|Proteobacteria,43CB3@68525|delta/epsilon subdivisions,2YTAN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG2200 FOG EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,sCache_2
k59_201549_1	572477.Alvin_1110	1.45e-65	221.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,1RNHV@1236|Gammaproteobacteria,1WXN2@135613|Chromatiales	135613|Chromatiales	M	Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)	-	-	2.4.1.129,3.4.16.4	ko:K05365	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase,UB2H
k59_314893_1	159087.Daro_0938	3.95e-114	336.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,2VH9Q@28216|Betaproteobacteria,2KUWH@206389|Rhodocyclales	206389|Rhodocyclales	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
k59_905808_1	313596.RB2501_04490	8.31e-25	103.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,4NKQV@976|Bacteroidetes,1HYSN@117743|Flavobacteriia	976|Bacteroidetes	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_905808_2	313596.RB2501_04495	1.24e-43	157.0	COG2267@1|root,COG4249@1|root,COG2267@2|Bacteria,COG4249@2|Bacteria,4NK0J@976|Bacteroidetes,1I11C@117743|Flavobacteriia	976|Bacteroidetes	I	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF676,Peptidase_C14
k59_905809_1	1535422.ND16A_2884	5.45e-31	113.0	COG2128@1|root,COG2128@2|Bacteria,1RASD@1224|Proteobacteria,1S391@1236|Gammaproteobacteria,2Q7N7@267889|Colwelliaceae	1236|Gammaproteobacteria	O	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
k59_1264198_1	1537917.JU82_01635	1.59e-94	280.0	COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,42N66@68525|delta/epsilon subdivisions,2YMY7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate	ate	-	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	ATE_C,ATE_N
k59_1264198_2	1249480.B649_10660	4.96e-33	123.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,42MKD@68525|delta/epsilon subdivisions,2YMRD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k59_146528_2	1537917.JU82_08920	2.08e-18	84.3	COG1808@1|root,COG1808@2|Bacteria,1NMS3@1224|Proteobacteria,42PXT@68525|delta/epsilon subdivisions,2YNR0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Domain of unknown function (DUF389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
k59_1727873_1	1165841.SULAR_10414	7.25e-07	49.7	COG3022@1|root,COG3022@2|Bacteria,1Q5IV@1224|Proteobacteria,42QYB@68525|delta/epsilon subdivisions,2YNY3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the UPF0246 family	-	-	-	ko:K09861	-	-	-	-	ko00000	-	-	-	H2O2_YaaD
k59_1264225_1	709032.Sulku_1894	2.56e-46	156.0	COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,42NSS@68525|delta/epsilon subdivisions,2YNZK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
k59_560209_1	1537917.JU82_09795	2.17e-127	376.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,42N30@68525|delta/epsilon subdivisions,2YMCR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
k59_1439781_1	709032.Sulku_0753	8.49e-88	265.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,42M8S@68525|delta/epsilon subdivisions,2YNN2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
k59_1493197_1	103690.17130377	2.93e-05	47.0	COG1450@1|root,COG1450@2|Bacteria,1G1WE@1117|Cyanobacteria,1HK9H@1161|Nostocales	1117|Cyanobacteria	NU	Type II and III secretion system protein	gspD	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
k59_1493197_2	387093.SUN_1674	3.88e-73	226.0	COG2842@1|root,COG2842@2|Bacteria,1QWU9@1224|Proteobacteria,43BVJ@68525|delta/epsilon subdivisions,2YTAG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	ATPases associated with a variety of cellular activities	ctsP	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_22
k59_1030971_1	387093.SUN_0456	1.43e-158	454.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,42NDT@68525|delta/epsilon subdivisions,2YMIS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
k59_1030971_2	1165841.SULAR_09149	2.35e-35	124.0	COG0494@1|root,COG0494@2|Bacteria,1RDGJ@1224|Proteobacteria,42RGH@68525|delta/epsilon subdivisions,2YP5E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage	nudH	-	-	ko:K08311	ko03018,map03018	-	R10816	RC00002	ko00000,ko00001,ko01000,ko03019	-	-	-	NUDIX
k59_1610141_2	709032.Sulku_0479	1.2e-165	469.0	COG1868@1|root,COG1868@2|Bacteria,1MX01@1224|Proteobacteria,42N2Y@68525|delta/epsilon subdivisions,2YMHG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar motor switch protein	fliM	-	-	ko:K02416	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliM,FliMN_C
k59_1669618_1	709032.Sulku_0608	5.91e-95	286.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,42SCV@68525|delta/epsilon subdivisions,2YPRK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar motor	motB	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
k59_1850968_2	159087.Daro_3939	1.89e-65	202.0	COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,2VR5S@28216|Betaproteobacteria,2KWBJ@206389|Rhodocyclales	206389|Rhodocyclales	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
k59_615676_2	502025.Hoch_5411	9.93e-08	54.3	COG0647@1|root,COG0647@2|Bacteria	2|Bacteria	G	UMP catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_6,Hydrolase_like
k59_201659_1	159087.Daro_1385	6.34e-31	109.0	2BY27@1|root,2ZWNS@2|Bacteria,1P58N@1224|Proteobacteria,2W6DQ@28216|Betaproteobacteria,2KZI3@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_201659_2	96561.Dole_2127	4.66e-15	75.1	COG4191@1|root,COG4191@2|Bacteria,1R95R@1224|Proteobacteria,42PEG@68525|delta/epsilon subdivisions,2WM8J@28221|Deltaproteobacteria,2MMRZ@213118|Desulfobacterales	28221|Deltaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k59_1730149_1	1304883.KI912532_gene92	4.37e-147	420.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,2VH2M@28216|Betaproteobacteria,2KUDP@206389|Rhodocyclales	206389|Rhodocyclales	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
k59_1788247_1	979533.F1D0V1_9CAUD	9.4e-127	378.0	4QGAG@10239|Viruses,4R0KB@35237|dsDNA viruses  no RNA stage,4QUA4@28883|Caudovirales,4QNFP@10744|Podoviridae	10744|Podoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1559965_1	709032.Sulku_0119	3.19e-61	196.0	COG0739@1|root,COG0739@2|Bacteria,1MY2X@1224|Proteobacteria,42U06@68525|delta/epsilon subdivisions,2YP2U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_204296_1	1249480.B649_02405	1.96e-164	465.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,42MZR@68525|delta/epsilon subdivisions,2YN0Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
k59_970722_2	929558.SMGD1_1855	3.16e-34	127.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,42M7H@68525|delta/epsilon subdivisions,2YMPK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
k59_1559972_1	709032.Sulku_1179	1.02e-36	131.0	COG3134@1|root,COG3134@2|Bacteria,1PRQN@1224|Proteobacteria,42TTY@68525|delta/epsilon subdivisions,2YPV8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	17 kDa surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Rick_17kDa_Anti
k59_438100_2	1537917.JU82_10880	1.34e-48	158.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,42MDJ@68525|delta/epsilon subdivisions,2YMUT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
k59_970736_1	159087.Daro_3008	9.58e-103	304.0	COG1305@1|root,COG1305@2|Bacteria,1MVMI@1224|Proteobacteria,2VH3S@28216|Betaproteobacteria,2KUAT@206389|Rhodocyclales	206389|Rhodocyclales	E	Bacterial transglutaminase-like N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
k59_1315785_1	709032.Sulku_2170	5.11e-95	280.0	COG0807@1|root,COG0807@2|Bacteria,1MWZR@1224|Proteobacteria,42N2Q@68525|delta/epsilon subdivisions,2YM8K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate	ribA	-	3.5.4.25	ko:K01497	ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024	M00125	R00425	RC00293,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydro2
k59_1853541_1	497321.C664_17145	1.66e-49	176.0	COG0683@1|root,COG1638@1|root,COG0683@2|Bacteria,COG1638@2|Bacteria,1MX94@1224|Proteobacteria,2VHQ4@28216|Betaproteobacteria	28216|Betaproteobacteria	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_1853541_2	1249480.B649_06355	7.2e-74	233.0	COG0477@1|root,COG2814@2|Bacteria,1MXPM@1224|Proteobacteria,42NXE@68525|delta/epsilon subdivisions,2YTHH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EGP	LacY proton/sugar symporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_907891_2	387093.SUN_1074	2.39e-34	122.0	2E8DE@1|root,332RW@2|Bacteria,1N96Q@1224|Proteobacteria,42W98@68525|delta/epsilon subdivisions,2YQFB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1559999_1	159087.Daro_3896	7.29e-106	327.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VJBX@28216|Betaproteobacteria,2KU9U@206389|Rhodocyclales	206389|Rhodocyclales	NT	Methyl-accepting chemotaxis protein	pilJ	-	-	ko:K02660	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	MCPsignal,PilJ
k59_148351_1	420662.Mpe_A0761	2.75e-39	145.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,2VP3I@28216|Betaproteobacteria,1KMPD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
k59_1315844_1	1537917.JU82_09140	8.77e-101	298.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,42MFP@68525|delta/epsilon subdivisions,2YMI2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components	-	-	-	ko:K02034,ko:K12370	ko02010,ko02024,map02010,map02024	M00239,M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
k59_148354_1	396588.Tgr7_0004	1.49e-44	162.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,1RNB2@1236|Gammaproteobacteria,1WVZ4@135613|Chromatiales	135613|Chromatiales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_148354_2	90814.KL370892_gene2229	1.15e-24	100.0	COG3954@1|root,COG3954@2|Bacteria,1MWN9@1224|Proteobacteria,1RMS7@1236|Gammaproteobacteria,461IU@72273|Thiotrichales	72273|Thiotrichales	C	PFAM Phosphoribulokinase uridine kinase	-	-	2.7.1.19	ko:K00855	ko00710,ko01100,ko01120,ko01200,map00710,map01100,map01120,map01200	M00165,M00166	R01523	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK
k59_1853611_1	1300005.R9RFC9_9CAUD	2.24e-85	264.0	4QGGR@10239|Viruses,4QZHR@35237|dsDNA viruses  no RNA stage,4QUGZ@28883|Caudovirales,4QNY3@10744|Podoviridae	10744|Podoviridae	S	viral capsid	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_679858_1	1165841.SULAR_06958	2e-30	116.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,42NCH@68525|delta/epsilon subdivisions,2YMW7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_679858_3	387093.SUN_2055	1.48e-64	213.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,42M35@68525|delta/epsilon subdivisions,2YM7I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0354	DXP_synthase_N,Transket_pyr,Transketolase_C
k59_316553_1	709032.Sulku_0409	6.31e-89	280.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1NQKX@1224|Proteobacteria,43CB3@68525|delta/epsilon subdivisions,2YTAN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG2200 FOG EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,sCache_2
k59_563011_1	317025.Tcr_1851	2.2e-12	69.3	COG2199@1|root,COG3290@1|root,COG3290@2|Bacteria,COG3706@2|Bacteria,1NAG0@1224|Proteobacteria,1RPKX@1236|Gammaproteobacteria,463M4@72273|Thiotrichales	72273|Thiotrichales	T	Double sensory domain of two-component sensor kinase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_3
k59_1853625_1	373903.Hore_18820	1.39e-49	174.0	COG0614@1|root,COG1807@1|root,COG0614@2|Bacteria,COG1807@2|Bacteria,1UF6C@1239|Firmicutes,254QF@186801|Clostridia	186801|Clostridia	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
k59_204420_2	1537917.JU82_06955	7.28e-34	125.0	COG0176@1|root,COG0176@2|Bacteria,1N9G3@1224|Proteobacteria,42MCK@68525|delta/epsilon subdivisions,2YMRY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
k59_438212_1	709032.Sulku_0620	2.18e-59	189.0	COG4976@1|root,COG4976@2|Bacteria,1R1JX@1224|Proteobacteria,43DAA@68525|delta/epsilon subdivisions,2YTHB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM)	cmoA	-	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_25
k59_204457_2	1249480.B649_08765	1.07e-32	125.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42N29@68525|delta/epsilon subdivisions,2YMFM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA helicase	rep	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_204457_3	709032.Sulku_0715	1.03e-40	144.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42NES@68525|delta/epsilon subdivisions,2YMT3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Type II secretion system	ctsF	-	-	ko:K02455,ko:K12278	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
k59_1612290_1	159087.Daro_2397	1.85e-109	317.0	COG1596@1|root,COG1596@2|Bacteria,1RFBH@1224|Proteobacteria,2VKB3@28216|Betaproteobacteria,2KVHI@206389|Rhodocyclales	206389|Rhodocyclales	M	COG1596 Periplasmic protein involved in polysaccharide export	wza	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export
k59_1612290_2	1304883.KI912532_gene2905	1.16e-10	60.8	COG3206@1|root,COG3206@2|Bacteria,1MVBX@1224|Proteobacteria,2VMDA@28216|Betaproteobacteria,2KUAM@206389|Rhodocyclales	206389|Rhodocyclales	M	Polysaccharide chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
k59_1853677_1	709032.Sulku_2369	1.42e-104	308.0	COG0760@1|root,COG0760@2|Bacteria,1N20M@1224|Proteobacteria,42SXW@68525|delta/epsilon subdivisions,2YPHS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase_2,SurA_N,SurA_N_3
k59_1267061_1	159087.Daro_3426	5.29e-114	360.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,2VI3R@28216|Betaproteobacteria,2KUB1@206389|Rhodocyclales	206389|Rhodocyclales	L	Helicase associated domain (HA2)  Add an annotation	hrpA	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
k59_1034025_2	1267534.KB906754_gene3182	1.68e-33	116.0	COG1278@1|root,COG1278@2|Bacteria,3Y57X@57723|Acidobacteria	57723|Acidobacteria	K	Cold shock protein domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k59_204487_1	1120999.JONM01000034_gene3996	3.96e-32	122.0	COG0644@1|root,COG0644@2|Bacteria,1MZVI@1224|Proteobacteria,2VH6J@28216|Betaproteobacteria,2KPKS@206351|Neisseriales	206351|Neisseriales	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
k59_1853698_1	1173264.KI913949_gene3377	7.08e-64	205.0	COG0676@1|root,COG0676@2|Bacteria,1G41U@1117|Cyanobacteria,1HA9U@1150|Oscillatoriales	1117|Cyanobacteria	G	PFAM Aldose 1-epimerase	-	-	5.1.3.15	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	-	R02739	RC00563	ko00000,ko00001,ko01000	-	-	-	Aldose_epim
k59_679971_1	709032.Sulku_0862	9.85e-101	310.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,42MPK@68525|delta/epsilon subdivisions,2YMFX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,SurA_N_3
k59_1034063_3	1249480.B649_10460	7.75e-11	57.8	2B2IW@1|root,31V40@2|Bacteria,1QSZI@1224|Proteobacteria,4332K@68525|delta/epsilon subdivisions,2YSGU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1267103_1	1168067.JAGP01000001_gene1903	5.52e-79	246.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,45ZXJ@72273|Thiotrichales	72273|Thiotrichales	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	2.3.1.179,2.3.1.41	ko:K00647,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_679977_1	55601.VANGNB10_cI1794c	2.55e-09	63.9	COG0834@1|root,COG2199@1|root,COG0834@2|Bacteria,COG2199@2|Bacteria,1NS3W@1224|Proteobacteria,1SKY3@1236|Gammaproteobacteria,1XSPX@135623|Vibrionales	135623|Vibrionales	ET	Bacterial extracellular solute-binding proteins, family 3	-	-	2.7.7.65	ko:K20957	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF,SBP_bac_3
k59_438285_2	159087.Daro_4099	9.46e-60	190.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2VJNG@28216|Betaproteobacteria,2KVMK@206389|Rhodocyclales	206389|Rhodocyclales	E	ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
k59_792700_1	1123326.JFBL01000013_gene378	5.3e-63	212.0	COG2604@1|root,COG2604@2|Bacteria,1R4P0@1224|Proteobacteria,42NB8@68525|delta/epsilon subdivisions,2YMMI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	hmm pf01973	pseE	-	-	-	-	-	-	-	-	-	-	-	MAF_flag10
k59_1378199_1	1537917.JU82_08485	5.17e-112	345.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,42M70@68525|delta/epsilon subdivisions,2YMJM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_1442705_1	1144343.PMI41_04982	1.93e-100	310.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TTRU@28211|Alphaproteobacteria,43J0J@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	K	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_262564_2	1249480.B649_00380	5.28e-46	149.0	2BRG4@1|root,32MA7@2|Bacteria,1Q36H@1224|Proteobacteria,42WUT@68525|delta/epsilon subdivisions,2YQQJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_262564_3	1249480.B649_00375	2.44e-27	105.0	2A50M@1|root,30TNT@2|Bacteria,1PDM4@1224|Proteobacteria,42QJ6@68525|delta/epsilon subdivisions,2YPYD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	AMIN domain	-	-	-	-	-	-	-	-	-	-	-	-	AMIN
k59_501580_1	709032.Sulku_0858	1.71e-121	350.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,42NTG@68525|delta/epsilon subdivisions,2YNB7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	abc transporter atp-binding protein	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
k59_501580_2	709032.Sulku_0857	1.55e-11	62.0	2FGS9@1|root,348MQ@2|Bacteria,1P3H2@1224|Proteobacteria,42SDS@68525|delta/epsilon subdivisions,2YPE7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF4149
k59_971038_1	1537917.JU82_06165	1.11e-77	232.0	COG2050@1|root,COG2050@2|Bacteria,1RK46@1224|Proteobacteria,42UJU@68525|delta/epsilon subdivisions,2YT62@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
k59_971038_2	709032.Sulku_0919	3.73e-19	86.3	COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,42MCR@68525|delta/epsilon subdivisions,2YNV0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EK	PFAM Aminotransferase class I and II	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
k59_971042_1	1448139.AI20_06125	5.4e-29	119.0	COG0715@1|root,COG2199@1|root,COG0715@2|Bacteria,COG2199@2|Bacteria,1RGCV@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	yeaI	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0032879,GO:0040012,GO:0040013,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051270,GO:0051271,GO:0065007,GO:0071944,GO:1902021,GO:1902201,GO:2000145,GO:2000146	2.7.7.65	ko:K20959,ko:K21021	ko02025,ko05111,map02025,map05111	-	-	-	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_853	CHASE,EAL,GGDEF,MASE4,NMT1,PAS_3,PAS_4
k59_563202_2	159087.Daro_3920	2.38e-08	55.1	COG3678@1|root,COG3678@2|Bacteria,1N6PJ@1224|Proteobacteria,2VW8V@28216|Betaproteobacteria,2KX8F@206389|Rhodocyclales	206389|Rhodocyclales	NPTU	Heavy-metal resistance	-	-	-	-	-	-	-	-	-	-	-	-	LTXXQ
k59_1034161_1	1249480.B649_08110	9e-98	300.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,42NKZ@68525|delta/epsilon subdivisions,2YMT9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	RND efflux system, outer membrane lipoprotein	cmeC	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
k59_1442768_1	1537917.JU82_07175	2.09e-115	360.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2YMA1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
k59_1812945_2	1165841.SULAR_02753	2.1e-54	179.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,42M2J@68525|delta/epsilon subdivisions,2YN8F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	frdB	-	1.3.5.1,1.3.5.4	ko:K00240,ko:K00245	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0191	Fer2_3,Fer4_8
k59_1641369_1	1265505.ATUG01000001_gene3010	2.6e-18	88.6	COG3156@1|root,COG3156@2|Bacteria,1PZ6I@1224|Proteobacteria,42Q46@68525|delta/epsilon subdivisions,2WM8B@28221|Deltaproteobacteria,2MI8C@213118|Desulfobacterales	28221|Deltaproteobacteria	U	General secretion pathway protein K	-	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
k59_526611_1	387093.SUN_1241	6.6e-17	79.0	COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,42RT7@68525|delta/epsilon subdivisions,2YRF9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
k59_526611_2	387093.SUN_0385	1.51e-06	50.4	COG0583@1|root,COG0583@2|Bacteria,1R8CE@1224|Proteobacteria,42PKW@68525|delta/epsilon subdivisions,2YNJK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_1232431_2	159087.Daro_2748	7.97e-41	146.0	COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,2VI8B@28216|Betaproteobacteria,2KVFH@206389|Rhodocyclales	206389|Rhodocyclales	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	-	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
k59_753696_1	1163617.SCD_n00968	5.58e-56	184.0	COG0492@1|root,COG0492@2|Bacteria,1R12A@1224|Proteobacteria,2WHYF@28216|Betaproteobacteria	28216|Betaproteobacteria	O	ferredoxin-NADP+ reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1702249_1	1304883.KI912532_gene730	1.38e-183	517.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,2VIS0@28216|Betaproteobacteria,2KUN7@206389|Rhodocyclales	206389|Rhodocyclales	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
k59_1702249_2	159087.Daro_0070	7.72e-77	237.0	COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,2VIH5@28216|Betaproteobacteria,2KUWU@206389|Rhodocyclales	206389|Rhodocyclales	S	Displays ATPase and GTPase activities	-	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
k59_292578_1	1173024.KI912148_gene4897	5.27e-23	103.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1JK4Q@1189|Stigonemataceae	1117|Cyanobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
k59_52718_1	159087.Daro_0876	1.54e-135	395.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,2VJM1@28216|Betaproteobacteria,2KUPY@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,Pribosyltran
k59_407971_1	709032.Sulku_1126	1.84e-185	557.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2YMRQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_1525034_2	1537917.JU82_04405	1.2e-135	387.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,43ADI@68525|delta/epsilon subdivisions,2YT1T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
k59_1232469_1	90814.KL370891_gene506	6.53e-70	221.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,1RM9H@1236|Gammaproteobacteria,460AA@72273|Thiotrichales	72273|Thiotrichales	Q	ABC transporter permease	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
k59_753801_1	1249480.B649_10475	2.67e-66	218.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,42MFA@68525|delta/epsilon subdivisions,2YMUE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
k59_753801_3	1249480.B649_10460	1.85e-32	114.0	2B2IW@1|root,31V40@2|Bacteria,1QSZI@1224|Proteobacteria,4332K@68525|delta/epsilon subdivisions,2YSGU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_753801_4	563040.Saut_0762	3.06e-18	80.5	28QM5@1|root,3192M@2|Bacteria,1Q1JK@1224|Proteobacteria,42TV6@68525|delta/epsilon subdivisions,2YPT2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_52804_1	1537917.JU82_00270	1.28e-112	335.0	COG0477@1|root,COG2814@2|Bacteria,1MVKJ@1224|Proteobacteria,43DA9@68525|delta/epsilon subdivisions,2YSK6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_1349069_1	395494.Galf_1115	7.74e-14	70.5	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,2VHR1@28216|Betaproteobacteria,44V1R@713636|Nitrosomonadales	28216|Betaproteobacteria	J	B3/4 domain	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k59_1349069_2	395494.Galf_1116	2.79e-63	194.0	COG0776@1|root,COG0776@2|Bacteria,1RH5Z@1224|Proteobacteria,2VT12@28216|Betaproteobacteria,44VWJ@713636|Nitrosomonadales	28216|Betaproteobacteria	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himA	-	-	ko:K04764	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k59_292696_1	525898.Sdel_1999	5.1e-45	155.0	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,42QTE@68525|delta/epsilon subdivisions,2YR90@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_1525147_2	1165841.SULAR_07173	1.62e-169	480.0	COG2957@1|root,COG2957@2|Bacteria,1MX65@1224|Proteobacteria,42NAS@68525|delta/epsilon subdivisions,2YN3V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the agmatine deiminase family	aguA	-	-	-	-	-	-	-	-	-	-	-	PAD_porph
k59_292701_1	1540257.JQMW01000011_gene2209	9.93e-80	241.0	COG4720@1|root,COG4720@2|Bacteria,1V1E7@1239|Firmicutes,25CJR@186801|Clostridia,36WX9@31979|Clostridiaceae	186801|Clostridia	S	ECF-type riboflavin transporter, S component	-	-	-	-	-	-	-	-	-	-	-	-	ECF-ribofla_trS
k59_753873_2	709032.Sulku_1739	1.75e-45	164.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2YRKW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0474 Cation transport ATPase	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
k59_1349197_1	709032.Sulku_1657	9.8e-79	249.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,430C9@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	TIGRFAM Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Hemerythrin,NIT,PilJ
k59_234162_1	1537917.JU82_08465	1.87e-122	364.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,42M4S@68525|delta/epsilon subdivisions,2YM8Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	-	-	1.12.5.1	ko:K05922	-	-	-	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
k59_408341_2	749222.Nitsa_0695	2.76e-37	129.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,42QTK@68525|delta/epsilon subdivisions,2YNW0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
k59_878566_1	1249480.B649_02390	1.65e-153	437.0	COG1868@1|root,COG1868@2|Bacteria,1MX01@1224|Proteobacteria,42N2Y@68525|delta/epsilon subdivisions,2YMHG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar motor switch protein	fliM	-	-	ko:K02416	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliM,FliMN_C
k59_1525276_1	1249480.B649_00740	7.24e-93	278.0	COG3637@1|root,COG3637@2|Bacteria,1R3QN@1224|Proteobacteria,42Y1W@68525|delta/epsilon subdivisions,2YQU0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_408387_2	159087.Daro_0309	3.55e-37	130.0	COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,2VHDK@28216|Betaproteobacteria,2KUA3@206389|Rhodocyclales	206389|Rhodocyclales	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
k59_408392_1	911045.PSE_2510	7.29e-101	309.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,2TRTQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
k59_408403_1	1110702.G8GIT1_9CAUD	2.37e-27	111.0	4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses  no RNA stage,4QRFY@28883|Caudovirales,4QI6A@10662|Myoviridae	10662|Myoviridae	S	Ribonucleotide reductase, barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1817369_2	1304883.KI912532_gene742	4.26e-106	317.0	COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,2VHR0@28216|Betaproteobacteria,2KUNT@206389|Rhodocyclales	206389|Rhodocyclales	T	Domain of unknown function (DUF3391)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3391,HD_5
k59_754226_1	709032.Sulku_0750	2.46e-91	275.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,42M3E@68525|delta/epsilon subdivisions,2YMQZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
k59_293002_1	159087.Daro_3709	8.51e-94	279.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,2VR8K@28216|Betaproteobacteria,2KW4Z@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
k59_293006_1	159087.Daro_0882	8.57e-34	122.0	COG2165@1|root,COG2165@2|Bacteria,1N7HN@1224|Proteobacteria,2VVYH@28216|Betaproteobacteria,2KZAM@206389|Rhodocyclales	206389|Rhodocyclales	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K10924	ko05111,map05111	-	-	-	ko00000,ko00001,ko02044	-	-	-	N_methyl
k59_1349501_1	366394.Smed_1897	2.76e-15	73.9	COG3728@1|root,COG3728@2|Bacteria,1QSWQ@1224|Proteobacteria,2V1KG@28211|Alphaproteobacteria,4BK5S@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	DNA packaging	-	-	-	ko:K07474	-	-	-	-	ko00000	-	-	-	-
k59_408689_1	1249480.B649_10410	6.78e-90	285.0	COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,42M8J@68525|delta/epsilon subdivisions,2YNGB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member	recD	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2,Viral_helicase1
k59_408689_2	1537917.JU82_08615	8.32e-26	103.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,42N1I@68525|delta/epsilon subdivisions,2YMA0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome	ccpA	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
k59_754399_1	492774.JQMB01000004_gene2075	5.66e-63	195.0	COG2259@1|root,COG2259@2|Bacteria,1RHKP@1224|Proteobacteria,2VG5B@28211|Alphaproteobacteria,4BNGS@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	DoxX	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
k59_1349602_1	1415778.JQMM01000001_gene1863	7.1e-07	56.6	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RX2N@1236|Gammaproteobacteria,1JAEN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_3
k59_53240_1	583345.Mmol_2279	1.04e-91	277.0	COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,2VHM8@28216|Betaproteobacteria,2KM0H@206350|Nitrosomonadales	206350|Nitrosomonadales	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
k59_1349652_1	546268.NEISUBOT_05443	4.96e-21	99.8	COG0340@1|root,COG1521@1|root,COG0340@2|Bacteria,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,2VK1G@28216|Betaproteobacteria,2KQC6@206351|Neisseriales	206351|Neisseriales	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33,6.3.4.15	ko:K01947,ko:K03525	ko00770,ko00780,ko01100,map00770,map00780,map01100	M00120	R01074,R02971,R03018,R04391,R05145	RC00002,RC00017,RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko00002,ko01000	-	-	-	BPL_C,BPL_LplA_LipB,Pan_kinase
k59_234631_1	717772.THIAE_01235	2.72e-175	507.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,460E6@72273|Thiotrichales	72273|Thiotrichales	E	Asparagine synthase, glutamine-hydrolyzing	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_293161_1	563040.Saut_1288	5.6e-76	237.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,42RTC@68525|delta/epsilon subdivisions,2YP4A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
k59_293161_2	1249480.B649_04625	4.82e-103	308.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,42NYD@68525|delta/epsilon subdivisions,2YNI5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Permease, YjgP YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_293193_4	765914.ThisiDRAFT_1458	7.63e-45	154.0	COG1238@1|root,COG1238@2|Bacteria,1MWED@1224|Proteobacteria,1RPT7@1236|Gammaproteobacteria,1WY8B@135613|Chromatiales	135613|Chromatiales	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
k59_293193_5	1541065.JRFE01000014_gene1496	1.28e-24	101.0	COG2518@1|root,COG2518@2|Bacteria,1G5KC@1117|Cyanobacteria,3VKZF@52604|Pleurocapsales	1117|Cyanobacteria	O	Ribosomal RNA adenine dimethylase	pcm	GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
k59_293194_2	487316.BBNM01000005_gene174	3.77e-44	154.0	COG4641@1|root,COG4641@2|Bacteria,1RD4C@1224|Proteobacteria,1RYDA@1236|Gammaproteobacteria,3NKBK@468|Moraxellaceae	1236|Gammaproteobacteria	S	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
k59_1349710_1	1123401.JHYQ01000006_gene70	8.78e-58	204.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,4602D@72273|Thiotrichales	72273|Thiotrichales	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k59_348327_1	159087.Daro_3068	1.17e-93	280.0	COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,2VJNM@28216|Betaproteobacteria,2KVY8@206389|Rhodocyclales	206389|Rhodocyclales	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Rrf2,Virul_fac_BrkB
k59_348327_2	159087.Daro_3067	0.000482	42.0	2C2C7@1|root,2Z85G@2|Bacteria,1PD07@1224|Proteobacteria,2VSM7@28216|Betaproteobacteria,2KWS4@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_408983_1	159087.Daro_0231	6.24e-16	76.6	COG1219@1|root,COG1219@2|Bacteria,1R8FT@1224|Proteobacteria,2VM85@28216|Betaproteobacteria,2KV8F@206389|Rhodocyclales	206389|Rhodocyclales	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small
k59_408983_3	159087.Daro_0276	6.17e-13	66.6	COG2894@1|root,COG2894@2|Bacteria,1MUEU@1224|Proteobacteria,2VJFP@28216|Betaproteobacteria,2KV0W@206389|Rhodocyclales	206389|Rhodocyclales	D	Belongs to the ParA family	minD	-	-	ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
k59_754606_1	159087.Daro_1376	5.25e-60	209.0	COG0582@1|root,COG0582@2|Bacteria,1NJY0@1224|Proteobacteria,2W1V6@28216|Betaproteobacteria,2KYDJ@206389|Rhodocyclales	206389|Rhodocyclales	L	viral genome integration into host DNA	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_348362_1	159087.Daro_1487	2.22e-175	501.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,2VKXT@28216|Betaproteobacteria,2KU7Y@206389|Rhodocyclales	206389|Rhodocyclales	KT	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF_2,HTH_8,Sigma54_activat
k59_754609_1	929558.SMGD1_0378	2.17e-34	137.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2YMB9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	chemotaxis protein	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
k59_53388_1	76114.ebA2143	7.35e-20	92.4	COG3203@1|root,COG3203@2|Bacteria,1RB94@1224|Proteobacteria,2VQW4@28216|Betaproteobacteria,2M006@206389|Rhodocyclales	206389|Rhodocyclales	M	Gram-negative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
k59_754650_1	709032.Sulku_0821	1.6e-62	195.0	COG0352@1|root,COG0352@2|Bacteria,1NMR6@1224|Proteobacteria,42TSZ@68525|delta/epsilon subdivisions,2YPHK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Thiamine monophosphate synthase	-	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
k59_754650_2	1537917.JU82_11480	1.34e-106	319.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,42M31@68525|delta/epsilon subdivisions,2YMGC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
k59_111178_1	1537917.JU82_09795	9.41e-99	300.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,42N30@68525|delta/epsilon subdivisions,2YMCR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
k59_293319_1	159087.Daro_3895	4.43e-31	126.0	COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VJSZ@28216|Betaproteobacteria,2KUBP@206389|Rhodocyclales	206389|Rhodocyclales	KNT	COG0643 Chemotaxis protein histidine kinase and related kinases	pilL	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,HATPase_c,Hpt,Response_reg
k59_879291_1	709032.Sulku_0925	1.51e-19	86.7	COG1362@1|root,COG1362@2|Bacteria,1NT1D@1224|Proteobacteria,42MN0@68525|delta/epsilon subdivisions,2YRFV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	M18 family aminopeptidase	-	-	3.4.11.21	ko:K01267	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	Peptidase_M18
k59_879291_2	1537917.JU82_07175	1.14e-92	300.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2YMA1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
k59_53449_2	709032.Sulku_1645	2.52e-34	125.0	COG1651@1|root,COG1651@2|Bacteria,1Q684@1224|Proteobacteria,432K4@68525|delta/epsilon subdivisions,2YSQB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_348486_1	1172190.M947_08135	1.97e-15	77.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42NFR@68525|delta/epsilon subdivisions,2YMNU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_3,PAS_9
k59_348486_2	326298.Suden_0106	4.7e-16	79.3	COG3829@1|root,COG5001@1|root,COG3829@2|Bacteria,COG5001@2|Bacteria,1R4H0@1224|Proteobacteria	1224|Proteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,NIT,PAS_9
k59_53454_1	1249480.B649_11390	6.99e-91	286.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2YMW5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,TarH,dCache_2,sCache_2
k59_409165_1	717773.Thicy_1193	3.15e-75	245.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,1RMPV@1236|Gammaproteobacteria,4606X@72273|Thiotrichales	72273|Thiotrichales	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN
k59_348548_1	1165841.SULAR_04893	1.35e-105	308.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,42NR9@68525|delta/epsilon subdivisions,2YN03@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
k59_1293519_1	1165841.SULAR_00860	3.95e-87	262.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,42NTG@68525|delta/epsilon subdivisions,2YNB7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	abc transporter atp-binding protein	iamA	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
k59_1293519_2	1165841.SULAR_00855	6.93e-139	402.0	COG0767@1|root,COG3113@1|root,COG0767@2|Bacteria,COG3113@2|Bacteria,1MVPN@1224|Proteobacteria,42MG3@68525|delta/epsilon subdivisions,2YMCB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	ABC-type transport system involved in resistance to organic solvents permease component	iamB	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE,STAS,STAS_2
k59_1704433_1	1304883.KI912532_gene2	2.73e-10	60.5	COG1639@1|root,COG1639@2|Bacteria,1R4P9@1224|Proteobacteria,2VPPP@28216|Betaproteobacteria,2KVX9@206389|Rhodocyclales	206389|Rhodocyclales	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_1704433_2	159087.Daro_3311	1.38e-76	234.0	COG0631@1|root,COG0631@2|Bacteria,1N72S@1224|Proteobacteria,2VK9S@28216|Betaproteobacteria,2KVCJ@206389|Rhodocyclales	206389|Rhodocyclales	T	phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	PP2C_2
k59_648257_1	1249480.B649_09140	1.83e-109	331.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,42M35@68525|delta/epsilon subdivisions,2YM7I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0354	DXP_synthase_N,Transket_pyr,Transketolase_C
k59_1000035_1	1165841.SULAR_04668	8.77e-46	157.0	COG1596@1|root,COG1596@2|Bacteria	2|Bacteria	M	polysaccharide export	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
k59_1469238_1	1537917.JU82_02905	6.5e-73	223.0	COG0746@1|root,COG0746@2|Bacteria,1NEIC@1224|Proteobacteria,42SCE@68525|delta/epsilon subdivisions,2YPMS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
k59_60732_1	709032.Sulku_2342	3.1e-90	286.0	COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,1QUIU@1224|Proteobacteria,42M7I@68525|delta/epsilon subdivisions,2YMX0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG3893 inactivated superfamily I helicase	addB	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
k59_1469248_1	317025.Tcr_1851	4.31e-11	64.3	COG2199@1|root,COG3290@1|root,COG3290@2|Bacteria,COG3706@2|Bacteria,1NAG0@1224|Proteobacteria,1RPKX@1236|Gammaproteobacteria,463M4@72273|Thiotrichales	72273|Thiotrichales	T	Double sensory domain of two-component sensor kinase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_3
k59_253689_1	1089552.KI911559_gene272	1.5e-11	68.2	COG4665@1|root,COG4665@2|Bacteria,1RG47@1224|Proteobacteria,2VG07@28211|Alphaproteobacteria,2JYQJ@204441|Rhodospirillales	204441|Rhodospirillales	Q	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
k59_193389_2	1249480.B649_09855	6.02e-101	295.0	COG2862@1|root,COG2862@2|Bacteria,1NFSW@1224|Proteobacteria,43ACB@68525|delta/epsilon subdivisions,2YT0K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Uncharacterized protein family, UPF0114	-	-	-	-	-	-	-	-	-	-	-	-	UPF0114
k59_1842121_1	90814.KL370891_gene1500	1.72e-65	214.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,1RMSF@1236|Gammaproteobacteria,4604V@72273|Thiotrichales	72273|Thiotrichales	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
k59_429232_1	887898.HMPREF0551_1358	9.09e-38	142.0	COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria,2VJGZ@28216|Betaproteobacteria,1JZZ7@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Lytic murein transglycosylase B	mltB	-	-	ko:K08305	-	-	-	-	ko00000,ko01000,ko01011	-	GH103	-	SLT_2
k59_369123_1	439235.Dalk_5003	4.37e-55	182.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42Q40@68525|delta/epsilon subdivisions,2WKJ7@28221|Deltaproteobacteria,2MK6F@213118|Desulfobacterales	28221|Deltaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_74413_1	1249480.B649_07715	9.13e-127	377.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,42MGF@68525|delta/epsilon subdivisions,2YN0E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the UbiD family	menA	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0396	UbiD
k59_1548491_2	1117319.PSPO_01575	6.16e-45	153.0	COG2801@1|root,COG2801@2|Bacteria,1MZ45@1224|Proteobacteria,1RSNX@1236|Gammaproteobacteria,2Q00G@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	L	COG2801 Transposase and inactivated derivatives	ylbG	-	-	-	-	-	-	-	-	-	-	-	HTH_29,rve,rve_2,rve_3
k59_1548491_3	520709.F985_04056	1.47e-13	68.6	COG2801@1|root,COG2801@2|Bacteria,1MWNX@1224|Proteobacteria,1RW9F@1236|Gammaproteobacteria,3NJTA@468|Moraxellaceae	1236|Gammaproteobacteria	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_23,HTH_28,HTH_32,rve,rve_3
k59_1024613_3	1168067.JAGP01000001_gene1367	1.7e-29	117.0	COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,1RNGY@1236|Gammaproteobacteria,45ZRS@72273|Thiotrichales	72273|Thiotrichales	C	TIGRFAM nitrite reductase NAD(P)H , large subunit	-	-	1.7.1.15	ko:K00362	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2
k59_493351_1	387092.NIS_1099	6.11e-52	179.0	COG0477@1|root,COG2814@2|Bacteria,1N2NP@1224|Proteobacteria,42PHM@68525|delta/epsilon subdivisions,2YNJI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_1605751_2	709032.Sulku_1882	9.16e-31	116.0	COG1090@1|root,COG1090@2|Bacteria,1MUB4@1224|Proteobacteria,42QUU@68525|delta/epsilon subdivisions,2YNXM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Epimerase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
k59_1723370_1	159087.Daro_1023	2.93e-99	305.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2VHVH@28216|Betaproteobacteria,2KUHI@206389|Rhodocyclales	206389|Rhodocyclales	G	PQQ-like domain	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ
k59_311629_1	929558.SMGD1_1897	2.09e-75	250.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42MS0@68525|delta/epsilon subdivisions,2YMTX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,dCache_3
k59_1433931_1	1304883.KI912532_gene1684	2.8e-82	248.0	COG0861@1|root,COG0861@2|Bacteria,1MXSK@1224|Proteobacteria,2VHZ5@28216|Betaproteobacteria,2KW4M@206389|Rhodocyclales	206389|Rhodocyclales	P	Integral membrane protein TerC family	-	-	-	-	-	-	-	-	-	-	-	-	TerC
k59_1433931_2	159087.Daro_3361	5.85e-50	166.0	COG2423@1|root,COG2423@2|Bacteria,1N3EI@1224|Proteobacteria,2WFNY@28216|Betaproteobacteria,2KVWM@206389|Rhodocyclales	206389|Rhodocyclales	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
k59_671472_1	1165841.SULAR_09634	4.93e-50	165.0	COG3531@1|root,COG3531@2|Bacteria,1RIN9@1224|Proteobacteria,42ZIN@68525|delta/epsilon subdivisions,2YRQ0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Thioredoxin	-	-	-	ko:K07396	-	-	-	-	ko00000	-	-	-	Thioredoxin_5
k59_671472_2	387093.SUN_0563	1.19e-18	83.6	COG0492@1|root,COG0492@2|Bacteria,1NDW6@1224|Proteobacteria,42MUD@68525|delta/epsilon subdivisions,2YMV2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	pyridine nucleotide-disulfide oxidoreductase	trxB_2	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	FixS,Pyr_redox_3
k59_371210_1	709032.Sulku_1126	4.14e-101	325.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2YMRQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_1845256_2	709032.Sulku_0817	9.54e-95	281.0	COG1189@1|root,COG1189@2|Bacteria,1MWP5@1224|Proteobacteria,42R2J@68525|delta/epsilon subdivisions,2YNYE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Hemolysin	tlyA	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
k59_1309352_1	34506.g3042	3.36e-86	278.0	COG4770@1|root,KOG0238@2759|Eukaryota,38B7N@33154|Opisthokonta,3B9PR@33208|Metazoa,3D08X@33213|Bilateria,40C9Z@6231|Nematoda,1KXZF@119089|Chromadorea,40WC1@6236|Rhabditida	33208|Metazoa	C	propionyl-CoA carboxylase activity	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
k59_76580_1	1163617.SCD_n02722	8.18e-09	55.5	COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,2VHAX@28216|Betaproteobacteria	28216|Betaproteobacteria	P	sulfurtransferase	sseA	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
k59_76580_2	1123392.AQWL01000005_gene3232	6.01e-50	160.0	COG2920@1|root,COG2920@2|Bacteria,1N2HP@1224|Proteobacteria,2VVGF@28216|Betaproteobacteria,1KT6M@119069|Hydrogenophilales	119069|Hydrogenophilales	P	DsrC like protein	-	-	-	-	-	-	-	-	-	-	-	-	DsrC
k59_431342_1	709032.Sulku_0959	2.62e-79	248.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42Z0P@68525|delta/epsilon subdivisions,2YR4F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG0513 Superfamily II DNA and RNA	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k59_554495_2	159087.Daro_3328	1.31e-133	391.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,2VHJ9@28216|Betaproteobacteria,2KUU8@206389|Rhodocyclales	206389|Rhodocyclales	S	modulator of DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
k59_962112_1	378806.STAUR_4342	6.06e-64	205.0	COG1175@1|root,COG1175@2|Bacteria,1MWB7@1224|Proteobacteria,42SSV@68525|delta/epsilon subdivisions,2WP8Z@28221|Deltaproteobacteria,2YUSJ@29|Myxococcales	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	thuF	-	-	ko:K02025,ko:K10237	ko02010,map02010	M00204,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.17	-	-	BPD_transp_1
k59_962112_2	1190603.AJYD01000015_gene947	0.000134	43.9	COG1653@1|root,COG1653@2|Bacteria,1MX9J@1224|Proteobacteria,1RPYT@1236|Gammaproteobacteria,1XUUS@135623|Vibrionales	135623|Vibrionales	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10236	ko02010,map02010	M00204	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.17	-	-	SBP_bac_1
k59_493453_2	749222.Nitsa_1420	2.2e-38	139.0	COG0662@1|root,COG0836@1|root,COG0662@2|Bacteria,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,42MDP@68525|delta/epsilon subdivisions,2YMW3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	GM	Belongs to the mannose-6-phosphate isomerase type 2 family	manC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
k59_1665390_1	414684.RC1_3320	2.55e-37	145.0	28HPK@1|root,2Z7XJ@2|Bacteria,1NBHR@1224|Proteobacteria,2TT3N@28211|Alphaproteobacteria,2JQ8P@204441|Rhodospirillales	204441|Rhodospirillales	S	Bacteriophage head to tail connecting protein	-	-	-	-	-	-	-	-	-	-	-	-	Head-tail_con
k59_493468_1	765912.Thimo_2227	2.87e-33	122.0	COG1192@1|root,COG1192@2|Bacteria,1MWRE@1224|Proteobacteria,1RMZN@1236|Gammaproteobacteria,1WWIN@135613|Chromatiales	135613|Chromatiales	D	PFAM Cobyrinic acid a,c-diamide synthase	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
k59_196214_1	667632.KB890187_gene3158	1.96e-24	102.0	COG3515@1|root,COG3515@2|Bacteria,1MY80@1224|Proteobacteria,2VN8Y@28216|Betaproteobacteria,1K3AK@119060|Burkholderiaceae	28216|Betaproteobacteria	S	TIGRFAM type VI secretion-associated protein, ImpA family	impA	-	-	ko:K11902	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	ImpA_N
k59_196214_2	883126.HMPREF9710_05203	2.7e-06	53.1	COG3210@1|root,COG3501@1|root,COG3210@2|Bacteria,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,2VJDF@28216|Betaproteobacteria,475MH@75682|Oxalobacteraceae	28216|Betaproteobacteria	U	Phage late control gene D protein (GPD)	-	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	Gp5_C,Phage_GPD
k59_1309405_1	1218074.BAXZ01000006_gene1702	7.02e-61	209.0	28HIF@1|root,2Z7TX@2|Bacteria,1MY24@1224|Proteobacteria,2VM3H@28216|Betaproteobacteria,1K5U9@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Bacteriophage replication gene A protein (GPA)	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPA
k59_493481_1	387093.SUN_1891	1.2e-117	347.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,42MCI@68525|delta/epsilon subdivisions,2YMR4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
k59_196233_1	159087.Daro_0998	3.06e-60	200.0	COG3278@1|root,COG3278@2|Bacteria,1P8T0@1224|Proteobacteria,2VNAW@28216|Betaproteobacteria,2KU91@206389|Rhodocyclales	206389|Rhodocyclales	O	Belongs to the heme-copper respiratory oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_196233_2	1304883.KI912532_gene1806	2.65e-09	54.7	COG3094@1|root,COG3094@2|Bacteria,1MZN6@1224|Proteobacteria,2VUWN@28216|Betaproteobacteria,2KWZ1@206389|Rhodocyclales	206389|Rhodocyclales	S	Invasion gene expression up-regulator SirB	sirB	-	-	-	-	-	-	-	-	-	-	-	SirB
k59_196236_1	1249480.B649_02250	2.44e-197	556.0	COG0739@1|root,COG0739@2|Bacteria,1NESH@1224|Proteobacteria,42MGB@68525|delta/epsilon subdivisions,2YMT7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_1139850_1	1304883.KI912532_gene395	3.77e-146	419.0	COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,2VI6V@28216|Betaproteobacteria,2KV1J@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
k59_493522_1	944547.ABLL_0811	2.22e-93	278.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,42ZBD@68525|delta/epsilon subdivisions,2YREI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	-	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
k59_671640_1	395494.Galf_2887	2.76e-120	376.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,44V8X@713636|Nitrosomonadales	28216|Betaproteobacteria	V	TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_671646_1	709032.Sulku_1108	8.42e-29	112.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,42NYD@68525|delta/epsilon subdivisions,2YNI5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Permease, YjgP YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_671646_2	1537917.JU82_11690	3.93e-104	307.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,42RTC@68525|delta/epsilon subdivisions,2YP4A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
k59_493541_1	323261.Noc_1174	1.55e-15	73.6	COG2878@1|root,COG2878@2|Bacteria,1MUWU@1224|Proteobacteria,1RNSJ@1236|Gammaproteobacteria,1WY08@135613|Chromatiales	135613|Chromatiales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4_21
k59_671666_2	709032.Sulku_0212	2.99e-11	62.4	COG0790@1|root,COG0790@2|Bacteria	2|Bacteria	S	beta-lactamase activity	-	-	3.1.1.32,3.1.1.4	ko:K01058,ko:K07126,ko:K12543	ko00564,ko00565,ko00590,ko00591,ko00592,ko01100,ko01110,map00564,map00565,map00590,map00591,map00592,map01100,map01110	M00330	R01315,R01316,R01317,R02053,R02054,R04034,R07064,R07379,R07387,R07859,R07860	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko00002,ko01000,ko02000,ko02044	1.B.17,3.A.1.109.4	-	-	Sel1
k59_1551836_1	90814.KL370891_gene630	6.23e-106	315.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,1RNDC@1236|Gammaproteobacteria,4606B@72273|Thiotrichales	72273|Thiotrichales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
k59_141744_1	497321.C664_08713	2.96e-43	145.0	COG0286@1|root,COG0286@2|Bacteria,1NN38@1224|Proteobacteria,2VNIU@28216|Betaproteobacteria	28216|Betaproteobacteria	V	site-specific DNA-methyltransferase (adenine-specific) activity	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
k59_141744_2	497321.C664_08708	1.2e-52	179.0	COG0286@1|root,COG0286@2|Bacteria,1PC7K@1224|Proteobacteria,2VN7I@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Eco57I restriction-modification methylase	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Eco57I
k59_196316_3	159087.Daro_1506	4.87e-15	70.9	COG1433@1|root,COG1433@2|Bacteria,1RD9P@1224|Proteobacteria,2VUUQ@28216|Betaproteobacteria,2KX3E@206389|Rhodocyclales	206389|Rhodocyclales	S	Dinitrogenase iron-molybdenum cofactor	-	-	-	ko:K02596	-	-	-	-	ko00000	-	-	-	Nitro_FeMo-Co
k59_901808_1	338969.Rfer_0684	1.55e-94	290.0	COG0438@1|root,COG0438@2|Bacteria,1PVZ8@1224|Proteobacteria,2VPK3@28216|Betaproteobacteria	28216|Betaproteobacteria	M	COG0438 Glycosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4
k59_1258830_1	159087.Daro_0210	1.94e-147	422.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,2VH6W@28216|Betaproteobacteria,2KV8N@206389|Rhodocyclales	206389|Rhodocyclales	NU	Pilus assembly protein	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
k59_1024949_1	1120970.AUBZ01000019_gene3563	3.17e-111	333.0	COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,1RPUP@1236|Gammaproteobacteria,465AR@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components	nrtC	-	-	ko:K15576	ko00910,ko02010,map00910,map02010	M00438	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16.1,3.A.1.16.2	-	-	NMT1_2
k59_1194855_2	1249480.B649_02635	2.14e-106	328.0	COG0726@1|root,COG1649@1|root,COG0726@2|Bacteria,COG1649@2|Bacteria,1MWR2@1224|Proteobacteria,43AG1@68525|delta/epsilon subdivisions,2YT1V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Hypothetical glycosyl hydrolase family 13	-	-	-	ko:K11931	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000	-	-	-	GHL13,Polysacc_deac_1
k59_1605975_1	1249480.B649_02370	1.06e-114	339.0	COG1419@1|root,COG1419@2|Bacteria,1MUQW@1224|Proteobacteria,42NBF@68525|delta/epsilon subdivisions,2YN28@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar biosynthesis	flhF	-	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	SRP54
k59_609909_1	944547.ABLL_1210	4.66e-39	149.0	COG3829@1|root,COG5001@1|root,COG3829@2|Bacteria,COG5001@2|Bacteria,1R4H0@1224|Proteobacteria,42Q74@68525|delta/epsilon subdivisions,2YMQI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,EAL,GGDEF,PAS_3,PAS_9
k59_1605977_1	1537917.JU82_01295	1.52e-157	461.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,42M6A@68525|delta/epsilon subdivisions,2YMN6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA_synt_2f
k59_1845546_1	1121405.dsmv_3402	1.88e-103	310.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,42MHK@68525|delta/epsilon subdivisions,2WJAZ@28221|Deltaproteobacteria,2MHTR@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
k59_1371500_2	944547.ABLL_0027	1.27e-71	221.0	COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,42NZV@68525|delta/epsilon subdivisions,2YN88@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	ABC transporter permease	modB	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
k59_1258864_1	1537917.JU82_03200	1.66e-68	213.0	COG2733@1|root,COG2733@2|Bacteria,1R4JT@1224|Proteobacteria,42RK1@68525|delta/epsilon subdivisions,2YPBZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_783919_1	1304883.KI912532_gene2394	7.05e-112	325.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,2VH8C@28216|Betaproteobacteria,2KVCE@206389|Rhodocyclales	206389|Rhodocyclales	E	serine acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep
k59_1371503_2	1249480.B649_00075	6.6e-59	189.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,42MWK@68525|delta/epsilon subdivisions,2YMIH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
k59_671793_1	395495.Lcho_1457	1.96e-88	265.0	COG1462@1|root,COG1462@2|Bacteria,1NDU8@1224|Proteobacteria,2VI5Y@28216|Betaproteobacteria,1KKDZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Curli production assembly/transport component CsgG	csgG	-	-	-	-	-	-	-	-	-	-	-	CsgG
k59_554807_1	709032.Sulku_1058	1.31e-72	234.0	COG2895@1|root,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,42N3C@68525|delta/epsilon subdivisions,2YNS9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_EFTU
k59_1258909_1	1537917.JU82_01910	5.73e-92	276.0	2A4YW@1|root,30TKN@2|Bacteria,1PDH4@1224|Proteobacteria,42SHS@68525|delta/epsilon subdivisions,2YPG5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_493681_1	717773.Thicy_1572	2.28e-99	298.0	COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,1RMEQ@1236|Gammaproteobacteria,4603B@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
k59_1079200_1	1249480.B649_09200	2.7e-109	323.0	COG0176@1|root,COG0176@2|Bacteria,1N9G3@1224|Proteobacteria,42MCK@68525|delta/epsilon subdivisions,2YMRY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
k59_1845609_1	1304883.KI912532_gene775	2.55e-91	281.0	COG0569@1|root,COG0569@2|Bacteria,1MW8R@1224|Proteobacteria,2VIH1@28216|Betaproteobacteria,2KUYB@206389|Rhodocyclales	206389|Rhodocyclales	C	COG0569 K transport systems, NAD-binding component	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
k59_1845609_2	159087.Daro_0031	1.12e-13	69.7	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VKD8@28216|Betaproteobacteria,2KV57@206389|Rhodocyclales	206389|Rhodocyclales	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activ_2
k59_196453_1	391735.Veis_1083	8.64e-42	145.0	COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria,2VI56@28216|Betaproteobacteria,4AB7B@80864|Comamonadaceae	28216|Betaproteobacteria	F	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism	add	-	3.5.4.2,3.5.4.4	ko:K01488,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01244,R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
k59_845113_1	1121004.ATVC01000014_gene2020	1.94e-89	277.0	COG3350@1|root,COG3350@2|Bacteria,1MWWK@1224|Proteobacteria,2VH88@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM Methane phenol toluene hydroxylase	-	-	-	ko:K16242	ko00361,ko00362,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00623,map01100,map01120,map01220	M00548	R03560,R03608,R10042,R10043	RC00046,RC00490	ko00000,ko00001,ko00002,ko01000	-	-	-	Phenol_Hydrox,YHS
k59_1140035_2	1249480.B649_02780	5.18e-69	221.0	COG0642@1|root,COG0642@2|Bacteria,1N5IQ@1224|Proteobacteria,42M9P@68525|delta/epsilon subdivisions,2YN0U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	cprS	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
k59_1606052_2	1249480.B649_01780	1.71e-112	326.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,42S1J@68525|delta/epsilon subdivisions,2YT8I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k59_1665597_1	1304883.KI912532_gene2224	6.71e-95	290.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,2VH2X@28216|Betaproteobacteria,2KVE3@206389|Rhodocyclales	206389|Rhodocyclales	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
k59_554844_1	749222.Nitsa_2094	3.86e-42	151.0	COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,42RGM@68525|delta/epsilon subdivisions,2YPC6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	HlyD family secretion protein	-	-	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	HlyD_3,HlyD_D23
k59_962392_1	1132855.KB913035_gene266	4.11e-53	184.0	COG0515@1|root,COG0515@2|Bacteria,1R6F6@1224|Proteobacteria,2W1UW@28216|Betaproteobacteria,2KKN2@206350|Nitrosomonadales	206350|Nitrosomonadales	KLT	Lipopolysaccharide kinase (Kdo/WaaP) family	-	-	-	-	-	-	-	-	-	-	-	-	Kdo
k59_962392_2	1112274.KI911560_gene1166	1.25e-05	47.0	COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,2VMSK@28216|Betaproteobacteria,2KMFR@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k59_720652_1	717773.Thicy_0632	1.43e-106	328.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,1RME8@1236|Gammaproteobacteria,45ZVM@72273|Thiotrichales	72273|Thiotrichales	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_1079227_1	1380394.JADL01000001_gene2827	1.64e-21	96.7	COG3511@1|root,COG3511@2|Bacteria,1MVNS@1224|Proteobacteria,2U1QU@28211|Alphaproteobacteria,2JPJA@204441|Rhodospirillales	204441|Rhodospirillales	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Phosphoesterase
k59_1079227_2	1249480.B649_06665	8.21e-61	196.0	COG1092@1|root,COG1092@2|Bacteria,1PUHQ@1224|Proteobacteria,42Q87@68525|delta/epsilon subdivisions,2YNGM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the methyltransferase superfamily	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
k59_1667675_2	1537917.JU82_01075	6.72e-32	119.0	COG0666@1|root,COG0666@2|Bacteria,1Q2UY@1224|Proteobacteria,42WAJ@68525|delta/epsilon subdivisions,2YQKP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_4,Ank_5
k59_1028055_1	870187.Thini_0255	5.41e-48	164.0	COG3676@1|root,COG3677@1|root,COG3676@2|Bacteria,COG3677@2|Bacteria,1R7ZF@1224|Proteobacteria,1S6YQ@1236|Gammaproteobacteria,461FS@72273|Thiotrichales	1236|Gammaproteobacteria	L	PFAM Insertion element protein	-	-	-	ko:K07488	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_964974_1	709032.Sulku_2260	1.34e-97	311.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42M0A@68525|delta/epsilon subdivisions,2YNJ1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	cznA	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
k59_1028082_1	1165841.SULAR_05708	6.35e-148	422.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,42N8B@68525|delta/epsilon subdivisions,2YMRV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
k59_1028082_2	1165841.SULAR_05713	2.31e-24	101.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,42MVX@68525|delta/epsilon subdivisions,2YMSF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	iIT341.HP1134	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_557593_1	1537917.JU82_04385	2.34e-137	397.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,42M7K@68525|delta/epsilon subdivisions,2YMZY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
k59_1400196_1	1548903.A0A0A1IWQ3_9CAUD	1.33e-38	154.0	4QAWG@10239|Viruses,4QPII@28883|Caudovirales,4QI76@10662|Myoviridae	10662|Myoviridae	S	DNA helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1400196_2	1283079.M1IDW3_9CAUD	9.17e-20	91.3	4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses  no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae	10744|Podoviridae	S	DNA polymerase family A	-	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360	-	-	-	-	-	-	-	-	-	-	-
k59_171413_1	1537917.JU82_06900	3.33e-152	452.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,42NHZ@68525|delta/epsilon subdivisions,2YMTE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	5-methyltetrahydrofolate--homocysteine methyltransferase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
k59_1754006_1	1120977.JHUX01000003_gene947	1.21e-102	313.0	COG3845@1|root,COG3845@2|Bacteria,1NT0H@1224|Proteobacteria,1T1GV@1236|Gammaproteobacteria,3NJ3U@468|Moraxellaceae	1236|Gammaproteobacteria	S	ABC transporter	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
k59_1517729_1	580332.Slit_0847	2.93e-55	181.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,2VKJJ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM ATPase associated with various cellular activities, AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_1517729_2	1122604.JONR01000006_gene2583	1.77e-79	244.0	COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,1RNNP@1236|Gammaproteobacteria,1X3IY@135614|Xanthomonadales	135614|Xanthomonadales	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k59_1636653_2	709032.Sulku_0631	1.78e-62	199.0	COG1566@1|root,COG1566@2|Bacteria,1MWG0@1224|Proteobacteria,42NAT@68525|delta/epsilon subdivisions,2YPNZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
k59_1466060_1	1537917.JU82_00120	9.56e-232	649.0	COG1538@1|root,COG1538@2|Bacteria,1QWWG@1224|Proteobacteria,42PH5@68525|delta/epsilon subdivisions,2YMHH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_1466060_2	1249480.B649_07600	1.05e-89	269.0	COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,42M4G@68525|delta/epsilon subdivisions,2YN1Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
k59_1809602_1	1537917.JU82_02555	3.84e-185	525.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,42M7X@68525|delta/epsilon subdivisions,2YM91@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	GO:0003674,GO:0005488,GO:0005515,GO:0042802	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
k59_1754041_1	709032.Sulku_1245	7.42e-98	294.0	COG0842@1|root,COG0842@2|Bacteria,1MUIA@1224|Proteobacteria,43AEH@68525|delta/epsilon subdivisions,2YMAF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
k59_46346_1	1229205.BUPH_03210	9.4e-30	115.0	COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,2VH5M@28216|Betaproteobacteria,1K05V@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
k59_46346_2	395494.Galf_1136	1.52e-58	201.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,2VJ5Q@28216|Betaproteobacteria,44VGS@713636|Nitrosomonadales	28216|Betaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_1290196_1	525897.Dbac_1357	6.94e-63	207.0	COG3437@1|root,COG3437@2|Bacteria,1QW6V@1224|Proteobacteria	1224|Proteobacteria	KT	Response regulator containing a CheY-like receiver domain and an HD-GYP domain	MA20_23615	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5,PilZ,Response_reg
k59_171501_1	547163.BN979_04615	3.58e-12	69.7	COG0531@1|root,COG0531@2|Bacteria,2GJ75@201174|Actinobacteria,23495@1762|Mycobacteriaceae	201174|Actinobacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
k59_171501_2	1165841.SULAR_03267	1.09e-78	239.0	COG0035@1|root,COG0035@2|Bacteria,1MV4N@1224|Proteobacteria,42NNR@68525|delta/epsilon subdivisions,2YMH0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
k59_869752_1	455436.DS989812_gene1334	8.06e-126	372.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,1RN93@1236|Gammaproteobacteria,464G4@72275|Alteromonadaceae	1236|Gammaproteobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ASL_C,Lyase_1
k59_1466106_1	1165841.SULAR_04803	6.04e-116	335.0	COG4508@1|root,COG4508@2|Bacteria,1RAX1@1224|Proteobacteria,42MG5@68525|delta/epsilon subdivisions,2YN7I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM dUTPase	dut	-	-	-	-	-	-	-	-	-	-	-	dUTPase_2
k59_171509_1	709032.Sulku_2167	5.74e-34	127.0	COG3303@1|root,COG3303@2|Bacteria,1QUJG@1224|Proteobacteria,42RGW@68525|delta/epsilon subdivisions,2YMPH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
k59_1876697_1	675813.VIB_000229	1.04e-11	65.5	COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,1RVNC@1236|Gammaproteobacteria,1XUH0@135623|Vibrionales	135623|Vibrionales	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k59_1876697_2	1283284.AZUK01000001_gene1528	4.24e-19	78.2	COG0230@1|root,COG0230@2|Bacteria,1NGGS@1224|Proteobacteria,1SGDJ@1236|Gammaproteobacteria,1Y4X5@135624|Aeromonadales	135624|Aeromonadales	J	structural constituent of ribosome	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
k59_1636743_1	1249480.B649_10295	1.36e-76	235.0	COG2863@1|root,COG2863@2|Bacteria,1Q4WC@1224|Proteobacteria,42NFN@68525|delta/epsilon subdivisions,2YMWE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Plasminogen-binding protein pgbA N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PGBA_N
k59_1636757_1	1005048.CFU_3992	4.77e-64	213.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VI0I@28216|Betaproteobacteria,473Q4@75682|Oxalobacteraceae	28216|Betaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
k59_285078_1	1165841.SULAR_09639	3.15e-98	308.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,43BJ8@68525|delta/epsilon subdivisions,2YMMJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	penicillin-binding protein	pbpA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
k59_1636760_1	1132855.KB913035_gene631	1.21e-101	305.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,2VH32@28216|Betaproteobacteria,2KM6Q@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
k59_1108131_1	709032.Sulku_1861	1.75e-88	278.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,42MUY@68525|delta/epsilon subdivisions,2YMZF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	PFAM peptidase M3A and M3B thimet oligopeptidase F	prlC	-	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
k59_934147_1	159087.Daro_3343	3.2e-117	365.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VI3F@28216|Betaproteobacteria,2KUP6@206389|Rhodocyclales	206389|Rhodocyclales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1693297_1	159087.Daro_2404	2.2e-120	350.0	COG2348@1|root,COG2348@2|Bacteria,1MXFY@1224|Proteobacteria,2VNEW@28216|Betaproteobacteria,2KVBP@206389|Rhodocyclales	206389|Rhodocyclales	V	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
k59_1693297_2	596154.Alide2_0696	7.08e-22	93.2	COG0438@1|root,COG0438@2|Bacteria,1MVIM@1224|Proteobacteria,2VJT7@28216|Betaproteobacteria,4ABSS@80864|Comamonadaceae	28216|Betaproteobacteria	M	Glycosyl transferases group 1	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
k59_460030_1	1165841.SULAR_01783	4.88e-178	499.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,42MI2@68525|delta/epsilon subdivisions,2YMPY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
k59_1693302_1	1537917.JU82_10630	4.89e-118	339.0	COG1192@1|root,COG1192@2|Bacteria,1PZND@1224|Proteobacteria,42QVU@68525|delta/epsilon subdivisions,2YNYU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Involved in chromosome partitioning	-	-	-	-	-	-	-	-	-	-	-	-	CbiA
k59_934170_1	580332.Slit_0662	7.62e-106	316.0	COG1902@1|root,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,2VHDY@28216|Betaproteobacteria,44VQV@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	1.3.1.34	ko:K00219	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_FMN
k59_869808_1	944547.ABLL_1400	6.96e-33	128.0	COG2202@1|root,COG4191@1|root,COG5001@1|root,COG5002@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,COG5001@2|Bacteria,COG5002@2|Bacteria,1MU2C@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GGDEF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9
k59_869808_2	572480.Arnit_0359	5.77e-21	95.5	COG0784@1|root,COG2198@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,43BU6@68525|delta/epsilon subdivisions,2YTGC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_9,Response_reg
k59_102683_1	696281.Desru_1116	1.29e-20	93.2	2BKZZ@1|root,32FGS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_2
k59_586750_1	1537917.JU82_04440	1.55e-98	303.0	COG1418@1|root,COG1418@2|Bacteria,1P7YA@1224|Proteobacteria,42KZ8@68525|delta/epsilon subdivisions,2YMQS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
k59_934192_1	748247.AZKH_1287	3.04e-44	167.0	COG0653@1|root,COG0653@2|Bacteria,1QZ1G@1224|Proteobacteria,2VQGH@28216|Betaproteobacteria,2KWYF@206389|Rhodocyclales	1224|Proteobacteria	U	Putative outer membrane beta-barrel porin, MtrB/PioB	-	-	-	-	-	-	-	-	-	-	-	-	MtrB_PioB
k59_641516_1	1298593.TOL_1062	9.75e-20	87.0	COG3176@1|root,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,1RZYE@1236|Gammaproteobacteria,1XK3N@135619|Oceanospirillales	135619|Oceanospirillales	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5
k59_337911_1	709032.Sulku_2174	3.44e-60	196.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,42MGU@68525|delta/epsilon subdivisions,2YMB7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
k59_996454_1	563040.Saut_0556	3.64e-101	309.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MHP@68525|delta/epsilon subdivisions,2YR82@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
k59_1290317_1	709032.Sulku_0245	1.88e-136	389.0	COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,42M1Y@68525|delta/epsilon subdivisions,2YMJA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Hydrolase	aguB	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
k59_1223730_1	765911.Thivi_3795	3.82e-57	201.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,1RPZ7@1236|Gammaproteobacteria,1WX60@135613|Chromatiales	135613|Chromatiales	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
k59_1693344_1	1121406.JAEX01000023_gene1482	2.62e-87	274.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,42NJZ@68525|delta/epsilon subdivisions,2WK1Q@28221|Deltaproteobacteria,2MG8Z@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
k59_337936_1	709032.Sulku_2370	1.79e-133	399.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42P9M@68525|delta/epsilon subdivisions,2YNH7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CZB,HAMP,MCPsignal,dCache_3
k59_399626_1	709032.Sulku_0261	1.44e-131	386.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2YTAQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
k59_586803_1	159087.Daro_1122	2.21e-87	261.0	COG1392@1|root,COG1392@2|Bacteria,1R4SP@1224|Proteobacteria,2VKF1@28216|Betaproteobacteria,2KW8U@206389|Rhodocyclales	206389|Rhodocyclales	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
k59_1290364_1	1249480.B649_03140	4.2e-88	271.0	COG0739@1|root,COG0739@2|Bacteria,1N19D@1224|Proteobacteria,42SMK@68525|delta/epsilon subdivisions,2YTS0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_1876855_1	1121035.AUCH01000016_gene2164	2e-85	262.0	COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,2VKUY@28216|Betaproteobacteria,2KVVJ@206389|Rhodocyclales	206389|Rhodocyclales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
k59_996536_1	1537917.JU82_11845	1.25e-12	67.8	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,42M2H@68525|delta/epsilon subdivisions,2YMM9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k59_996536_2	1165841.SULAR_09414	4.94e-100	305.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,42M6V@68525|delta/epsilon subdivisions,2YM9I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k59_1340532_1	1123326.JFBL01000010_gene689	7.46e-81	247.0	COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,42PR1@68525|delta/epsilon subdivisions,2YMT0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	forms the ion channels that couple flagellar rotation to proton sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine	motP	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
k59_1340532_2	1537917.JU82_09390	2.59e-113	337.0	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,42N3K@68525|delta/epsilon subdivisions,2YMK9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3,NTP_transferase
k59_745476_3	1249480.B649_10725	4.54e-38	130.0	COG0250@1|root,COG0250@2|Bacteria,1MU14@1224|Proteobacteria,42MPQ@68525|delta/epsilon subdivisions,2YMJK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
k59_1172648_1	387093.SUN_1453	5.69e-125	365.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,42N7U@68525|delta/epsilon subdivisions,2YN72@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	PFAM Radical SAM domain protein	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Radical_SAM
k59_1693458_1	1424334.W822_18295	2.23e-45	156.0	arCOG06842@1|root,338Y2@2|Bacteria,1Q096@1224|Proteobacteria,2W501@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function DUF1828	-	-	-	-	-	-	-	-	-	-	-	-	DUF1828
k59_1876926_1	247490.KSU1_B0173	1.12e-22	97.8	COG0084@1|root,COG0535@1|root,COG0084@2|Bacteria,COG0535@2|Bacteria,2IZ3Q@203682|Planctomycetes	203682|Planctomycetes	L	COG0084 Mg-dependent DNase	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_14,Radical_SAM,TatD_DNase
k59_1876926_2	1082933.MEA186_07087	1.89e-13	68.9	COG1430@1|root,COG1430@2|Bacteria,1MZBJ@1224|Proteobacteria,2UBSI@28211|Alphaproteobacteria,43KD9@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
k59_402485_1	563040.Saut_0637	5.07e-28	117.0	COG2199@1|root,COG4753@1|root,COG3706@2|Bacteria,COG4753@2|Bacteria,1MXBG@1224|Proteobacteria,42NGW@68525|delta/epsilon subdivisions,2YN86@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
k59_1111264_1	1121035.AUCH01000007_gene597	7.02e-89	285.0	COG4774@1|root,COG4774@2|Bacteria,1QU2Y@1224|Proteobacteria,2VUAA@28216|Betaproteobacteria,2KX9G@206389|Rhodocyclales	206389|Rhodocyclales	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	TonB_dep_Rec
k59_1226602_1	720554.Clocl_2465	4.96e-84	254.0	COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,247KR@186801|Clostridia,3WGUN@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
k59_463131_1	1000565.METUNv1_01780	3.48e-54	178.0	2CBK1@1|root,32RTI@2|Bacteria,1N1PI@1224|Proteobacteria,2VW3F@28216|Betaproteobacteria,2KYXA@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_341170_1	1355368.JART01000012_gene460	6.35e-31	121.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,42MB1@68525|delta/epsilon subdivisions,2YMVC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
k59_341170_2	1165841.SULAR_06298	1.31e-46	159.0	2ARMJ@1|root,31GY7@2|Bacteria,1QEMQ@1224|Proteobacteria,42VV2@68525|delta/epsilon subdivisions,2YQ9G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
k59_1226628_1	317025.Tcr_1810	5.19e-62	201.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,1RN8M@1236|Gammaproteobacteria,45ZU5@72273|Thiotrichales	72273|Thiotrichales	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
k59_644977_1	85643.Tmz1t_0454	3.47e-20	86.7	COG0824@1|root,COG0824@2|Bacteria,1RF7Q@1224|Proteobacteria,2VR5T@28216|Betaproteobacteria,2KWHU@206389|Rhodocyclales	206389|Rhodocyclales	S	Thioesterase-like superfamily	-	-	3.1.2.23	ko:K01075	ko00130,ko00362,ko01100,ko01110,ko01120,map00130,map00362,map01100,map01110,map01120	-	R01301	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	-	4HBT_2
k59_105491_1	666681.M301_1258	2.81e-100	308.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2VMVP@28216|Betaproteobacteria,2KMF9@206350|Nitrosomonadales	206350|Nitrosomonadales	G	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ,PQQ_2
k59_645005_1	159087.Daro_4142	7.63e-82	268.0	COG0745@1|root,COG0784@1|root,COG2202@1|root,COG5002@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2202@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,2WGIN@28216|Betaproteobacteria,2KZXD@206389|Rhodocyclales	206389|Rhodocyclales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_4,Response_reg
k59_820014_1	1249480.B649_01870	2.32e-61	199.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42NHE@68525|delta/epsilon subdivisions,2YMQ8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
k59_1757153_1	159087.Daro_3676	6.68e-91	290.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,2VJ68@28216|Betaproteobacteria,2KUAW@206389|Rhodocyclales	206389|Rhodocyclales	E	aminopeptidase N	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,Peptidase_M1
k59_1696386_1	1168067.JAGP01000001_gene1863	1.88e-57	194.0	COG2211@1|root,COG2211@2|Bacteria,1QVH9@1224|Proteobacteria,1SM3A@1236|Gammaproteobacteria,462WD@72273|Thiotrichales	72273|Thiotrichales	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_1226673_1	658187.LDG_7660	2.89e-92	284.0	COG2850@1|root,COG2850@2|Bacteria,1MW30@1224|Proteobacteria,1RN2Q@1236|Gammaproteobacteria,1JCBC@118969|Legionellales	118969|Legionellales	S	Cupin superfamily protein	ycfD	-	1.14.11.47	ko:K18850	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Cupin_4
k59_341270_1	1304883.KI912532_gene241	6.35e-153	439.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,2VI46@28216|Betaproteobacteria,2KVJW@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	paaK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
k59_1521134_2	1537917.JU82_09525	1.12e-41	137.0	COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,42TGC@68525|delta/epsilon subdivisions,2YQA0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
k59_1521134_3	1249480.B649_00805	8.6e-34	118.0	COG0093@1|root,COG0093@2|Bacteria,1RCWZ@1224|Proteobacteria,42RHR@68525|delta/epsilon subdivisions,2YP6F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
k59_48919_1	1125863.JAFN01000001_gene2546	3.46e-38	136.0	COG2069@1|root,COG2069@2|Bacteria,1QS8G@1224|Proteobacteria,437H2@68525|delta/epsilon subdivisions,2WKVX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM CO dehydrogenase acetyl-CoA synthase delta subunit	-	-	2.1.1.245	ko:K00194	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00357,M00377,M00422	R09096,R10219,R10243	RC00004,RC00113,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD
k59_48919_2	1125863.JAFN01000001_gene2545	1.76e-32	124.0	COG0369@1|root,COG1151@2|Bacteria,1NYH2@1224|Proteobacteria,42NE1@68525|delta/epsilon subdivisions,2WIVX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit	-	-	1.2.7.4	ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	M00377	R07157,R08034	RC00250,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Prismane
k59_645059_2	159087.Daro_2748	7.36e-68	213.0	COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,2VI8B@28216|Betaproteobacteria,2KVFH@206389|Rhodocyclales	206389|Rhodocyclales	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	-	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
k59_175170_1	1541065.JRFE01000057_gene6262	6.29e-18	83.2	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31,Ubie_methyltran
k59_105559_1	1537994.JQFW01000056_gene893	8.51e-11	67.8	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,1RYN7@1236|Gammaproteobacteria,46BC6@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Ring hydroxylating alpha subunit (catalytic domain)	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Ring_hydroxyl_A
k59_645075_1	1304883.KI912532_gene2354	3e-93	290.0	COG2766@1|root,COG2766@2|Bacteria,1MVW7@1224|Proteobacteria,2VI2M@28216|Betaproteobacteria,2KVKE@206389|Rhodocyclales	206389|Rhodocyclales	T	PrkA family serine protein kinase	prkA	-	-	ko:K07180	-	-	-	-	ko00000	-	-	-	AAA_PrkA,PrkA
k59_463260_1	1304883.KI912532_gene1019	1.09e-109	333.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2VH59@28216|Betaproteobacteria,2KVJZ@206389|Rhodocyclales	206389|Rhodocyclales	I	carboxylase	pccA	-	6.4.1.3	ko:K01965	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
k59_1757223_2	1537917.JU82_05770	2.17e-116	333.0	COG0652@1|root,COG0652@2|Bacteria,1R4KH@1224|Proteobacteria,42R08@68525|delta/epsilon subdivisions,2YNZU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
k59_228962_1	709032.Sulku_1906	1.63e-94	295.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42SS2@68525|delta/epsilon subdivisions,2YRAM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	CZB,MCPsignal
k59_645096_1	709032.Sulku_1415	1.53e-221	626.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,42N1K@68525|delta/epsilon subdivisions,2YMYX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1g,tRNA_bind
k59_288523_1	1249480.B649_01460	2.62e-95	295.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,42MB1@68525|delta/epsilon subdivisions,2YMVC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
k59_105608_1	1165841.SULAR_00185	1.57e-17	81.3	COG1538@1|root,COG1538@2|Bacteria,1Q066@1224|Proteobacteria,42RNJ@68525|delta/epsilon subdivisions,2YNZR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_105608_2	1165841.SULAR_00190	6.19e-71	221.0	COG1565@1|root,COG1565@2|Bacteria,1QNDB@1224|Proteobacteria,42MQ8@68525|delta/epsilon subdivisions,2YNBU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
k59_288541_1	1249480.B649_04855	1.08e-69	221.0	COG1306@1|root,COG1306@2|Bacteria,1MWBY@1224|Proteobacteria,42NSR@68525|delta/epsilon subdivisions,2YP0V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Putative glycosyl hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4015
k59_645139_1	1485544.JQKP01000002_gene1535	1.33e-114	336.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,2VIT9@28216|Betaproteobacteria,44VKF@713636|Nitrosomonadales	28216|Betaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
k59_645183_1	639282.DEFDS_0399	1.31e-25	107.0	COG0226@1|root,COG0226@2|Bacteria	2|Bacteria	P	phosphate ion binding	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
k59_525678_1	1265507.KB899636_gene1483	1.73e-63	207.0	COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,1RN5F@1236|Gammaproteobacteria,1Y3MJ@135624|Aeromonadales	135624|Aeromonadales	C	Malic enzyme, NAD binding domain	-	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
k59_73077_2	1537917.JU82_09695	1.29e-90	268.0	2994D@1|root,2ZW7V@2|Bacteria,1Q2D1@1224|Proteobacteria,42VGB@68525|delta/epsilon subdivisions,2YQM6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_73077_3	1249480.B649_03195	2.77e-54	174.0	COG0169@1|root,COG0169@2|Bacteria,1Q1X7@1224|Proteobacteria,431CA@68525|delta/epsilon subdivisions,2YSA4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	-	-	-	-	-	-	-	-	-	-	-	-	Shikimate_dh_N
k59_778843_1	1249480.B649_10400	2.16e-148	441.0	COG0715@1|root,COG0834@1|root,COG2199@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42UTN@68525|delta/epsilon subdivisions,2YTHQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EPT	NMT1/THI5 like	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	GGDEF,NMT1,SBP_bac_3
k59_1428674_1	1249480.B649_11390	6.96e-73	236.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2YMW5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,TarH,dCache_2,sCache_2
k59_136876_1	1132855.KB913035_gene1134	1.79e-106	317.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,2VI9I@28216|Betaproteobacteria,2KKIZ@206350|Nitrosomonadales	206350|Nitrosomonadales	P	Ammonium Transporter Family	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
k59_1840142_1	1120999.JONM01000024_gene3093	9.01e-38	132.0	COG2941@1|root,COG2941@2|Bacteria,1RAA1@1224|Proteobacteria,2VQRE@28216|Betaproteobacteria,2KPV8@206351|Neisseriales	206351|Neisseriales	H	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol	coq7	-	-	ko:K06134	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00128	R04984,R08775	RC01254	ko00000,ko00001,ko00002,ko01000	-	-	-	COQ7
k59_1840142_2	159087.Daro_0646	5.7e-62	193.0	2B1HQ@1|root,31TYQ@2|Bacteria,1MYSE@1224|Proteobacteria,2VTMU@28216|Betaproteobacteria,2KWP2@206389|Rhodocyclales	206389|Rhodocyclales	S	CNP1-like family	-	-	-	-	-	-	-	-	-	-	-	-	CNP1
k59_666294_1	2340.JV46_26250	3.96e-37	134.0	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,1S8R3@1236|Gammaproteobacteria,1JB4Y@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Transglycosylase SLT domain	ltg	-	-	-	-	-	-	-	-	-	-	-	DUF4124,SLT
k59_1840181_1	1165841.SULAR_09194	4.54e-63	199.0	COG0526@1|root,COG0526@2|Bacteria,1Q2Q0@1224|Proteobacteria,42W2S@68525|delta/epsilon subdivisions,2YQBT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CO	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
k59_1661198_1	1485544.JQKP01000004_gene560	7.21e-37	129.0	2EAZV@1|root,3350Q@2|Bacteria,1P6NQ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1840182_1	1249480.B649_11305	1.23e-42	152.0	COG3278@1|root,COG3278@2|Bacteria,1QAUQ@1224|Proteobacteria,42P3Q@68525|delta/epsilon subdivisions,2YNBX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the heme-copper respiratory oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	COX1
k59_1840182_2	1537917.JU82_02240	7.1e-88	263.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,43AWP@68525|delta/epsilon subdivisions,2YT3W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	COG1136 ABC-type antimicrobial peptide transport system ATPase component	-	-	-	ko:K02003,ko:K09810	ko02010,map02010	M00255,M00258	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.125	-	-	ABC_tran
k59_308689_1	522306.CAP2UW1_1154	2.36e-51	172.0	COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,2VH7F@28216|Betaproteobacteria,1KPU3@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
k59_308689_2	159087.Daro_3475	9.5e-25	99.4	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,2VIN7@28216|Betaproteobacteria,2KU9A@206389|Rhodocyclales	206389|Rhodocyclales	E	Belongs to the TrpC family	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
k59_1485480_1	1317122.ATO12_16790	5.37e-28	120.0	COG3287@1|root,COG3287@2|Bacteria,4NGTB@976|Bacteroidetes,1HX3X@117743|Flavobacteriia,2YIVQ@290174|Aquimarina	976|Bacteroidetes	S	FIST_C	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
k59_1253442_1	270374.MELB17_08311	1.45e-56	184.0	COG1083@1|root,COG1083@2|Bacteria,1QACI@1224|Proteobacteria,1RR92@1236|Gammaproteobacteria,464GG@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	COG1083 CMP-N-acetylneuraminic acid synthetase	neuA	-	2.7.7.43	ko:K00983	ko00520,ko01100,map00520,map01100	-	R01117,R04215	RC00152	ko00000,ko00001,ko01000	-	-	-	CTP_transf_3,Lipase_GDSL_2
k59_73139_1	395494.Galf_0450	3.05e-102	302.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,2VKVM@28216|Betaproteobacteria,44V6V@713636|Nitrosomonadales	28216|Betaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11,Fer4_7
k59_840558_1	159087.Daro_2029	1.72e-84	254.0	COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,2VI4M@28216|Betaproteobacteria,2KW7B@206389|Rhodocyclales	206389|Rhodocyclales	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
k59_1661221_1	709032.Sulku_0263	1.02e-72	229.0	COG0840@1|root,COG0840@2|Bacteria,1R5W9@1224|Proteobacteria,42SRV@68525|delta/epsilon subdivisions,2YR7J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	CZB,MCPsignal
k59_17223_1	1537917.JU82_05210	1.05e-06	48.9	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,42M8A@68525|delta/epsilon subdivisions,2YN5T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the SAICAR synthetase family	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
k59_252191_2	314225.ELI_10235	2.46e-12	65.1	COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,2TU3T@28211|Alphaproteobacteria,2K112@204457|Sphingomonadales	204457|Sphingomonadales	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
k59_136970_1	1249480.B649_10615	1.26e-104	314.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42NES@68525|delta/epsilon subdivisions,2YNJ6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	COG1459 Type II secretory pathway, component PulF	-	-	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
k59_136970_2	1249480.B649_10610	7.31e-67	218.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2YNUU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	COG2804 Type II secretory pathway ATPase PulE Tfp pilus assembly pathway ATPase PilB	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
k59_1019041_1	306264.CUP1774	8.41e-20	82.4	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,42SBD@68525|delta/epsilon subdivisions,2YPKU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
k59_1019041_2	1537917.JU82_01795	5.38e-51	162.0	COG0694@1|root,COG0694@2|Bacteria,1MVQ1@1224|Proteobacteria,42V85@68525|delta/epsilon subdivisions,2YPSA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Nitrogen fixation protein NifU	-	-	-	-	-	-	-	-	-	-	-	-	NifU
k59_958247_2	709032.Sulku_1951	1.74e-33	124.0	COG0642@1|root,COG2205@2|Bacteria,1RK1D@1224|Proteobacteria,42R91@68525|delta/epsilon subdivisions,2YNX3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
k59_778934_2	709032.Sulku_0683	1.76e-74	225.0	2A067@1|root,30N97@2|Bacteria,1Q1X8@1224|Proteobacteria,42UM9@68525|delta/epsilon subdivisions,2YPYZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1428780_1	1537917.JU82_10755	5.55e-141	405.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,42NNS@68525|delta/epsilon subdivisions,2YMQW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
k59_1074761_2	1121896.JMLU01000033_gene2821	2.35e-06	50.8	COG0666@1|root,COG0666@2|Bacteria,4NSDC@976|Bacteroidetes,1I46H@117743|Flavobacteriia,2NWMQ@237|Flavobacterium	976|Bacteroidetes	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_3,Ank_4,Ank_5
k59_308714_1	1249480.B649_09820	1.06e-137	400.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,42MFT@68525|delta/epsilon subdivisions,2YN9H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Ammonium Transporter	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
k59_252205_1	1537917.JU82_02305	3.89e-59	201.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,42MMR@68525|delta/epsilon subdivisions,2YMF0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	GM	Polysaccharide biosynthesis protein	pglF	-	4.2.1.135	ko:K15912	ko00520,map00520	-	-	-	ko00000,ko00001,ko01000	-	-	-	Polysacc_synt_2
k59_897973_1	1249480.B649_06660	4.44e-95	289.0	COG3511@1|root,COG3511@2|Bacteria,1MWVP@1224|Proteobacteria,43347@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	Phosphoesterase family	plcN	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	DUF756,Phosphoesterase
k59_1661254_2	1537917.JU82_08310	1.23e-164	464.0	COG0694@1|root,COG0822@1|root,COG0694@2|Bacteria,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,42MT6@68525|delta/epsilon subdivisions,2YMXY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CO	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins	iscU	-	-	ko:K13819	-	-	-	-	ko00000	-	-	-	Fer2_BFD,NifU,NifU_N
k59_191896_2	709032.Sulku_0767	8.19e-74	223.0	COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,42MCS@68525|delta/epsilon subdivisions,2YP49@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	peptidyl-prolyl cis-trans isomerase	slyD	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
k59_1019065_1	555779.Dthio_PD2194	9.77e-72	224.0	28RA4@1|root,2ZDPR@2|Bacteria,1NFZU@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_252217_2	1537917.JU82_06740	1.94e-78	236.0	COG1214@1|root,COG1214@2|Bacteria,1Q1J6@1224|Proteobacteria,42TUF@68525|delta/epsilon subdivisions,2YQ3R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	COG1214 Inactive homolog of metal-dependent proteases	tsaB	-	-	-	-	-	-	-	-	-	-	-	-
k59_1190832_1	1112274.KI911560_gene2056	4.6e-08	53.1	COG0175@1|root,COG0175@2|Bacteria,1MUCZ@1224|Proteobacteria,2VJH9@28216|Betaproteobacteria,2KM7X@206350|Nitrosomonadales	206350|Nitrosomonadales	EH	PFAM Phosphoadenosine phosphosulfate reductase	-	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
k59_1190832_2	640081.Dsui_1982	1.61e-90	276.0	COG2895@1|root,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,2VHYV@28216|Betaproteobacteria,2KUYT@206389|Rhodocyclales	206389|Rhodocyclales	H	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.7.4	ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_EFTU
k59_1367156_1	637911.AM305_00010	0.000327	48.1	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,1RMT9@1236|Gammaproteobacteria,1Y6W6@135625|Pasteurellales	135625|Pasteurellales	M	Arabinose 5-phosphate isomerase	Z012_11175	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
k59_1546635_1	1384054.N790_05560	3.36e-77	253.0	COG4773@1|root,COG4773@2|Bacteria,1MWUQ@1224|Proteobacteria,1SJYF@1236|Gammaproteobacteria,1X5UY@135614|Xanthomonadales	135614|Xanthomonadales	P	Outer membrane receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_1074786_1	1537917.JU82_11095	8.74e-177	521.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2YN6Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DNA mismatch repair MutS family	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_III,MutS_V
k59_1253521_1	1211579.PP4_00190	7.77e-46	149.0	2B9KW@1|root,322Z5@2|Bacteria,1RJJB@1224|Proteobacteria,1S6AK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1428825_1	387093.SUN_0201	6.78e-107	314.0	COG1013@1|root,COG1013@2|Bacteria,1MUY9@1224|Proteobacteria,42MQY@68525|delta/epsilon subdivisions,2YMWJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	pyruvate ferredoxin oxidoreductase	porB	-	1.2.7.1	ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
k59_252238_1	709032.Sulku_0353	2.48e-107	313.0	COG1192@1|root,COG1192@2|Bacteria,1N5CA@1224|Proteobacteria,42RDX@68525|delta/epsilon subdivisions,2YQN4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	involved in chromosome partitioning	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
k59_1253528_1	1286106.MPL1_13108	1.66e-35	140.0	COG3614@1|root,COG3850@1|root,COG5001@1|root,COG3614@2|Bacteria,COG3850@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9
k59_73197_1	709032.Sulku_1022	2.62e-05	45.1	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,42MVQ@68525|delta/epsilon subdivisions,2YMEZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CO	Thiol disulfide interchange protein	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin,Thioredoxin_2,Thioredoxin_7
k59_717563_1	1210884.HG799471_gene14655	1.51e-82	272.0	COG2834@1|root,COG3209@1|root,COG2834@2|Bacteria,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF4082,DUF4347,HemolysinCabind,SprB
k59_1604016_1	709032.Sulku_0824	3.08e-76	232.0	COG1226@1|root,COG1226@2|Bacteria,1R0RZ@1224|Proteobacteria,42UWU@68525|delta/epsilon subdivisions,2YQ24@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	TrkA-N domain	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	TrkA_C,TrkA_N
k59_1604016_2	709032.Sulku_0823	3.25e-52	177.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,42MW6@68525|delta/epsilon subdivisions,2YNJR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	potassium channel protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans,Ion_trans_2,TrkA_C,TrkA_N
k59_1487713_2	1304883.KI912532_gene2192	2.17e-124	357.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,2VQ3B@28216|Betaproteobacteria,2KV8C@206389|Rhodocyclales	206389|Rhodocyclales	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
k59_1192924_1	709032.Sulku_2497	2.78e-64	204.0	COG3439@1|root,COG3439@2|Bacteria,1PWY7@1224|Proteobacteria,42Y9J@68525|delta/epsilon subdivisions,2YRF7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1192924_2	326298.Suden_2053	1.96e-24	102.0	COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,42NZ4@68525|delta/epsilon subdivisions,2YNNY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	COG2067 Long-chain fatty acid transport protein	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k59_1549369_1	1565314.OA34_06910	3.63e-79	247.0	COG0715@1|root,COG0715@2|Bacteria,1MVJA@1224|Proteobacteria,42NMD@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	NMT1/THI5 like	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
k59_1843017_1	405948.SACE_4499	1.74e-45	157.0	COG0294@1|root,COG0294@2|Bacteria,2GJDQ@201174|Actinobacteria,4DYEE@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	-	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
k59_1137915_1	709032.Sulku_0129	1.52e-129	399.0	COG0439@1|root,COG1984@1|root,COG2049@1|root,COG0439@2|Bacteria,COG1984@2|Bacteria,COG2049@2|Bacteria,1MU4H@1224|Proteobacteria,42P49@68525|delta/epsilon subdivisions,2YNRZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EI	Allophanate hydrolase subunit 1	-	-	6.3.4.6	ko:K01941	ko00220,ko00791,ko01100,map00220,map00791,map01100	-	R00774	RC00378	ko00000,ko00001,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,CT_A_B,CT_C_D
k59_491721_1	1537917.JU82_00575	3.26e-110	329.0	COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,42M8Q@68525|delta/epsilon subdivisions,2YMSH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome c oxidase accessory protein	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
k59_1022144_1	387093.SUN_0178	5.5e-116	344.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,42M5M@68525|delta/epsilon subdivisions,2YMGW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	iIT341.HP0144	COX1
k59_1549378_1	1165841.SULAR_01773	7.63e-46	159.0	COG0791@1|root,COG0791@2|Bacteria,1R45H@1224|Proteobacteria,42NS0@68525|delta/epsilon subdivisions,2YN06@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,N_NLPC_P60,Peptidase_M15_4,SH3_6,SH3_7
k59_1843028_1	1537917.JU82_05600	9.46e-108	324.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,42MXN@68525|delta/epsilon subdivisions,2YN93@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EH	anthranilate synthase component	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP1282	Anth_synt_I_N,Chorismate_bind
k59_1369553_1	1123517.JOMR01000001_gene1073	3.28e-58	186.0	COG0664@1|root,COG0664@2|Bacteria,1N1ZG@1224|Proteobacteria,1SA1H@1236|Gammaproteobacteria,4623Y@72273|Thiotrichales	72273|Thiotrichales	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
k59_491752_1	563040.Saut_0555	2.88e-70	222.0	COG0095@1|root,COG0095@2|Bacteria,1RI3T@1224|Proteobacteria,42SQP@68525|delta/epsilon subdivisions,2YPI5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Biotin/lipoate A/B protein ligase family	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
k59_1192990_1	1537917.JU82_02500	9.33e-44	153.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,42M5U@68525|delta/epsilon subdivisions,2YMQH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	molybdopterin biosynthesis	moeA2	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
k59_1192990_2	1537917.JU82_02495	1.96e-59	186.0	COG0314@1|root,COG0314@2|Bacteria,1Q97D@1224|Proteobacteria,42REX@68525|delta/epsilon subdivisions,2YP4E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	molybdopterin converting factor	moaE	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
k59_1137981_1	1537917.JU82_04140	8.07e-70	224.0	COG0515@1|root,COG4886@1|root,COG0515@2|Bacteria,COG4886@2|Bacteria,1Q94S@1224|Proteobacteria,42X59@68525|delta/epsilon subdivisions,2YQUI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KLT	COG4886 Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	LRR_4,LRR_8,Pkinase
k59_960505_1	1005999.GLGR_3547	1.1e-85	266.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,1S1D8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
k59_429900_1	159087.Daro_3327	1.05e-77	236.0	COG2863@1|root,COG2863@2|Bacteria,1N7W9@1224|Proteobacteria,2WEG6@28216|Betaproteobacteria,2KW5A@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome C oxidase, cbb3-type, subunit III	cc43	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
k59_1137982_1	388739.RSK20926_19407	4.77e-17	82.8	COG0583@1|root,COG0583@2|Bacteria,1MWY0@1224|Proteobacteria,2TSD9@28211|Alphaproteobacteria,2P1AW@2433|Roseobacter	28211|Alphaproteobacteria	K	COG0583 Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_194221_1	388051.AUFE01000022_gene4769	5.22e-08	53.5	COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria,2VH08@28216|Betaproteobacteria,1K19W@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	msrP	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
k59_194221_2	159087.Daro_0620	1.06e-123	355.0	COG2717@1|root,COG2717@2|Bacteria,1RDUP@1224|Proteobacteria,2VRBQ@28216|Betaproteobacteria,2KW1M@206389|Rhodocyclales	206389|Rhodocyclales	C	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain	msrQ	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
k59_1843111_1	561230.PC1_1964	1.32e-37	140.0	COG0676@1|root,COG0676@2|Bacteria,1Q7VN@1224|Proteobacteria,1RQK0@1236|Gammaproteobacteria,1MS58@122277|Pectobacterium	1236|Gammaproteobacteria	G	Belongs to the glucose-6-phosphate 1-epimerase family	yeaD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716	5.1.3.15	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	-	R02739	RC00563	ko00000,ko00001,ko01000	-	-	-	Aldose_epim
k59_1137992_1	1537917.JU82_04100	4.27e-105	306.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,42NAA@68525|delta/epsilon subdivisions,2YMYI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
k59_1431720_1	640081.Dsui_3178	1.09e-93	285.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2W3RM@28216|Betaproteobacteria,2KZWY@206389|Rhodocyclales	206389|Rhodocyclales	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_491797_1	1249480.B649_02125	5.02e-34	129.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,42NIH@68525|delta/epsilon subdivisions,2YMVT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	FP	Guanosine pentaphosphate phosphohydrolase	gppA	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
k59_491797_2	1249480.B649_02120	1.8e-46	165.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2YMW4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_1137999_1	709032.Sulku_0078	1.75e-99	305.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria	1224|Proteobacteria	NT	Methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,CZB,MCPsignal
k59_719321_1	395965.Msil_3638	4.87e-13	65.9	2E633@1|root,330S6@2|Bacteria,1NDGF@1224|Proteobacteria,2UG8W@28211|Alphaproteobacteria,3NBGK@45404|Beijerinckiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_719321_2	1038866.KB902787_gene5565	9.94e-19	86.3	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2TRIQ@28211|Alphaproteobacteria,3JSRK@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
k59_429920_1	56780.SYN_01690	4.83e-16	79.3	COG0767@1|root,COG0767@2|Bacteria,1NSBS@1224|Proteobacteria,42ZGY@68525|delta/epsilon subdivisions	1224|Proteobacteria	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
k59_429920_2	1537917.JU82_01650	1.59e-19	86.7	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42M4T@68525|delta/epsilon subdivisions,2YMB2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_369836_1	1165096.ARWF01000001_gene1812	1.06e-82	256.0	COG3203@1|root,COG3203@2|Bacteria,1P7S0@1224|Proteobacteria,2VNY2@28216|Betaproteobacteria,2KM1P@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
k59_552252_1	1537917.JU82_04480	7.79e-94	283.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42MTX@68525|delta/epsilon subdivisions,2YMJQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.92	ko:K15895	ko00520,map00520	-	R09825	RC00006,RC00781	ko00000,ko00001,ko01000	-	-	-	DegT_DnrJ_EryC1
k59_1138016_1	1123517.JOMR01000001_gene879	1.87e-27	116.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,45ZMP@72273|Thiotrichales	72273|Thiotrichales	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4,Fer4_8
k59_1077284_1	1165841.SULAR_00875	4.9e-60	191.0	COG3637@1|root,COG3637@2|Bacteria,1Q5CU@1224|Proteobacteria,4311I@68525|delta/epsilon subdivisions,2YS8P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
k59_429945_2	1165841.SULAR_10179	4.46e-50	166.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,42NPN@68525|delta/epsilon subdivisions,2YMV8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10	ko:K00795	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364	R01658,R02003	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
k59_1431778_2	1128398.Curi_c01230	7.01e-91	274.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,248HE@186801|Clostridia,268XK@186813|unclassified Clostridiales	186801|Clostridia	L	TatD related DNase	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
k59_369864_1	709032.Sulku_1920	1.37e-99	297.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,42MGN@68525|delta/epsilon subdivisions,2YNAN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Chorismate mutase prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
k59_669390_2	159087.Daro_3050	1.33e-70	218.0	COG0802@1|root,COG0802@2|Bacteria,1RGYU@1224|Proteobacteria,2VSJY@28216|Betaproteobacteria,2KWJA@206389|Rhodocyclales	206389|Rhodocyclales	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
k59_310495_2	1249480.B649_06935	2.92e-67	218.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,42M81@68525|delta/epsilon subdivisions,2YMTF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_254541_1	159087.Daro_0041	2.15e-103	301.0	2CMG5@1|root,32SEP@2|Bacteria,1N1C2@1224|Proteobacteria,2VVAC@28216|Betaproteobacteria,2KZCB@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1307950_1	709032.Sulku_2336	1.32e-20	90.9	COG2194@1|root,COG2194@2|Bacteria,1MWS7@1224|Proteobacteria,42MI1@68525|delta/epsilon subdivisions,2YMPQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Sulfatase	eptA	-	2.7.8.43	ko:K03760	ko01503,map01503	M00722	R11555,R11556,R11557	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DUF1705,Sulfatase
k59_1307950_2	159087.Daro_3922	3.88e-26	111.0	COG3338@1|root,COG3338@2|Bacteria,1PEA6@1224|Proteobacteria,2VI5K@28216|Betaproteobacteria,2KUD9@206389|Rhodocyclales	206389|Rhodocyclales	P	carbonic anhydrase	ecaA	-	4.2.1.1	ko:K01674	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Carb_anhydrase
k59_405274_1	358220.C380_12055	2.09e-42	151.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,2VH1F@28216|Betaproteobacteria,4AD3Y@80864|Comamonadaceae	28216|Betaproteobacteria	T	Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
k59_290509_1	1121939.L861_15650	2.24e-31	116.0	COG0778@1|root,COG0778@2|Bacteria,1MZN8@1224|Proteobacteria,1RPVA@1236|Gammaproteobacteria,1XJ7R@135619|Oceanospirillales	135619|Oceanospirillales	C	Cob(II)yrinic acid a,c-diamide reductase	bluB	-	1.13.11.79	ko:K04719	ko00740,ko01100,map00740,map01100	-	R09083	RC00435,RC02413	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
k59_750955_1	322710.Avin_28200	2.64e-62	206.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,1RPBY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	ATPase related to the helicase subunit of the Holliday junction resolvase	rarA	GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0030894,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
k59_50836_1	387093.SUN_1818	2.58e-115	361.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,42NHZ@68525|delta/epsilon subdivisions,2YMTE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	5-methyltetrahydrofolate--homocysteine methyltransferase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
k59_875627_1	709032.Sulku_0733	4.24e-31	111.0	COG1516@1|root,COG1516@2|Bacteria,1PSYY@1224|Proteobacteria,42V8K@68525|delta/epsilon subdivisions,2YQ35@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar protein FliS	fliS	-	-	ko:K02422	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliS
k59_875627_2	1537917.JU82_04520	2.14e-22	89.4	29KSI@1|root,307PY@2|Bacteria,1PX63@1224|Proteobacteria,433IG@68525|delta/epsilon subdivisions,2YSQ0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_875627_3	1249480.B649_08690	1.01e-102	306.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,42N81@68525|delta/epsilon subdivisions,2YMAU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
k59_231270_1	159087.Daro_2932	3.68e-113	340.0	COG1944@1|root,COG1944@2|Bacteria,1MV7K@1224|Proteobacteria,2VHZY@28216|Betaproteobacteria,2KV2Z@206389|Rhodocyclales	206389|Rhodocyclales	O	redox protein, regulator of disulfide bond formation	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	YcaO
k59_750979_1	1366050.N234_25055	1.92e-152	437.0	COG1960@1|root,COG1960@2|Bacteria,1MU2V@1224|Proteobacteria,2VM0U@28216|Betaproteobacteria,1K5R3@119060|Burkholderiaceae	28216|Betaproteobacteria	C	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_875653_1	62928.azo2282	2.26e-15	75.9	COG0835@1|root,COG0835@2|Bacteria,1QVCF@1224|Proteobacteria,2VK5W@28216|Betaproteobacteria,2KVUN@206389|Rhodocyclales	206389|Rhodocyclales	NT	Two component signalling adaptor domain	-	-	-	-	-	-	-	-	-	-	-	-	CheW
k59_875653_2	159087.Daro_1925	1.52e-67	228.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,2VHTE@28216|Betaproteobacteria,2KVJB@206389|Rhodocyclales	206389|Rhodocyclales	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
k59_466203_1	1165841.SULAR_03642	4.82e-117	359.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,42MPZ@68525|delta/epsilon subdivisions,2YM8C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k59_999770_2	709032.Sulku_1821	8.52e-31	112.0	2ENFG@1|root,33G2V@2|Bacteria,1NPDC@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
k59_60413_1	582744.Msip34_1078	1.39e-12	65.5	COG1846@1|root,COG1846@2|Bacteria,1RH0E@1224|Proteobacteria,2VR3F@28216|Betaproteobacteria,2KMUW@206350|Nitrosomonadales	206350|Nitrosomonadales	K	PFAM regulatory protein MarR	-	-	-	-	-	-	-	-	-	-	-	-	MarR
k59_60413_2	882378.RBRH_02947	3.81e-14	73.6	COG1538@1|root,COG1538@2|Bacteria,1MUZZ@1224|Proteobacteria,2VH6M@28216|Betaproteobacteria,1K16Z@119060|Burkholderiaceae	28216|Betaproteobacteria	M	RND efflux system, outer membrane lipoprotein, NodT family	fusA2	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_1234588_1	395494.Galf_1849	2.23e-97	295.0	COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,2VHJ8@28216|Betaproteobacteria,44VEY@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA	rlmD	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
k59_1762898_2	1249480.B649_01460	5.31e-42	151.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,42MB1@68525|delta/epsilon subdivisions,2YMVC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
k59_823674_1	292415.Tbd_1443	4.5e-16	75.1	COG5592@1|root,COG5592@2|Bacteria,1N4TJ@1224|Proteobacteria,2VU5X@28216|Betaproteobacteria	28216|Betaproteobacteria	S	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
k59_823674_2	243233.MCA2402	6.83e-07	52.0	COG3448@1|root,COG3448@2|Bacteria,1MXJG@1224|Proteobacteria,1RYFC@1236|Gammaproteobacteria,1XEYX@135618|Methylococcales	135618|Methylococcales	T	HPP family	-	-	-	ko:K07168	-	-	-	-	ko00000	-	-	-	CBS,HPP
k59_1234599_1	1537917.JU82_08420	2.64e-180	514.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2YMA3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_236596_1	709032.Sulku_2027	9.59e-133	389.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,42MIH@68525|delta/epsilon subdivisions,2YRA4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing EAL and modified HD-GYP domains	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_236596_2	944547.ABLL_1138	3.76e-26	106.0	COG0745@1|root,COG0745@2|Bacteria,1Q456@1224|Proteobacteria,42RZX@68525|delta/epsilon subdivisions,2YP60@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_1410409_1	1249480.B649_02240	3.24e-47	169.0	COG3221@1|root,COG5001@1|root,COG3221@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YN16@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	GGDEF EAL family protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_9
k59_1410409_2	709032.Sulku_0453	6.26e-49	164.0	COG3439@1|root,COG3439@2|Bacteria,1Q0BS@1224|Proteobacteria,42RXE@68525|delta/epsilon subdivisions,2YP61@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
k59_2415_1	1121035.AUCH01000028_gene3252	6.61e-90	282.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VJGE@28216|Betaproteobacteria,2KV5M@206389|Rhodocyclales	206389|Rhodocyclales	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,Response_reg
k59_1704228_1	1249480.B649_01995	1.01e-34	125.0	COG0745@1|root,COG0745@2|Bacteria,1N7TJ@1224|Proteobacteria,42TRT@68525|delta/epsilon subdivisions,2YPV7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_1704228_2	1249480.B649_02000	3.03e-15	75.5	COG0642@1|root,COG2205@2|Bacteria,1Q179@1224|Proteobacteria,4313A@68525|delta/epsilon subdivisions,2YS9S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07645	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	-
k59_412658_1	1537917.JU82_01670	2.16e-101	325.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,43DMZ@68525|delta/epsilon subdivisions,2YMMS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_1528443_1	1537917.JU82_03470	1.32e-32	116.0	28QM5@1|root,319KE@2|Bacteria,1Q3DZ@1224|Proteobacteria,42X5X@68525|delta/epsilon subdivisions,2YQT9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
k59_1822032_1	1537917.JU82_09485	4.29e-119	351.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,42MGM@68525|delta/epsilon subdivisions,2YMUV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
k59_823716_1	709032.Sulku_1076	8.51e-39	136.0	COG3228@1|root,COG3228@2|Bacteria,1RAHF@1224|Proteobacteria,42QKQ@68525|delta/epsilon subdivisions,2YMYQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the MtfA family	-	-	-	ko:K09933	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_M90
k59_823716_2	709032.Sulku_1075	1.24e-37	126.0	2BPZI@1|root,32ITJ@2|Bacteria,1PBV9@1224|Proteobacteria,42VR5@68525|delta/epsilon subdivisions,2YQJA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_823716_3	709032.Sulku_1074	2.56e-23	93.6	COG0454@1|root,COG0456@2|Bacteria,1Q5DX@1224|Proteobacteria,4313C@68525|delta/epsilon subdivisions,2YSF5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_295117_1	159087.Daro_0805	2.82e-64	200.0	COG1192@1|root,COG1192@2|Bacteria,1QBJX@1224|Proteobacteria,2VPQ9@28216|Betaproteobacteria,2M01K@206389|Rhodocyclales	206389|Rhodocyclales	D	ATPase MipZ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	CbiA
k59_295117_2	159087.Daro_0804	4.69e-43	147.0	COG1414@1|root,COG1414@2|Bacteria,1Q7BI@1224|Proteobacteria,2VK7Y@28216|Betaproteobacteria,2KW6Q@206389|Rhodocyclales	206389|Rhodocyclales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
k59_2442_1	1537917.JU82_05050	8.5e-158	448.0	COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,43B0D@68525|delta/epsilon subdivisions,2YT4V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the pseudouridine synthase RluA family	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
k59_1234639_1	754476.Q7A_684	5.08e-91	273.0	COG0461@1|root,COG0461@2|Bacteria,1MW6F@1224|Proteobacteria,1RQYG@1236|Gammaproteobacteria,460FX@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
k59_530563_1	1304883.KI912532_gene397	1.22e-94	283.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,2VI8C@28216|Betaproteobacteria,2KUYY@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
k59_412688_1	159087.Daro_3804	5.77e-13	68.2	COG3836@1|root,COG3836@2|Bacteria,1MUSG@1224|Proteobacteria,2VK64@28216|Betaproteobacteria,2KUKM@206389|Rhodocyclales	206389|Rhodocyclales	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.2.52	ko:K02510	ko00350,ko01120,map00350,map01120	-	R01645,R01647	RC00307,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
k59_412688_2	1218084.BBJK01000089_gene5888	5.32e-43	156.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2WH2X@28216|Betaproteobacteria,1KIHC@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Activator of aromatic catabolism	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat,V4R,XylR_N
k59_1469076_1	1165841.SULAR_08357	9.88e-89	270.0	COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,42MDF@68525|delta/epsilon subdivisions,2YMNI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Pseudouridine synthase	sfhB	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
k59_1469076_3	1165841.SULAR_08362	2.44e-37	134.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,42N69@68525|delta/epsilon subdivisions,2YN3J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
k59_471643_1	1165841.SULAR_00135	2.34e-209	597.0	COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,42MY0@68525|delta/epsilon subdivisions,2YMT1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
k59_1528508_1	1123518.ARWI01000001_gene137	1.81e-77	242.0	COG0835@1|root,COG3437@1|root,COG0835@2|Bacteria,COG3437@2|Bacteria,1RD7I@1224|Proteobacteria,1SKFD@1236|Gammaproteobacteria,46261@72273|Thiotrichales	72273|Thiotrichales	T	Two component signalling adaptor domain	-	-	-	ko:K03415	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CheW,Response_reg
k59_1351795_1	1304883.KI912532_gene1573	7.93e-114	338.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,2VIKZ@28216|Betaproteobacteria,2KVFZ@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_1587018_1	1249480.B649_01880	6.1e-08	53.5	COG2433@1|root,COG2433@2|Bacteria,1QW3W@1224|Proteobacteria,42RB0@68525|delta/epsilon subdivisions,2YNE9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Pfam Transposase IS66	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
k59_1587018_2	1249480.B649_01885	9.94e-62	194.0	COG4659@1|root,COG4659@2|Bacteria,1NP43@1224|Proteobacteria,43BHC@68525|delta/epsilon subdivisions,2YQ00@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_588852_4	1433126.BN938_1744	3.61e-63	204.0	COG0863@1|root,COG0863@2|Bacteria,4NRE7@976|Bacteroidetes,2FP3W@200643|Bacteroidia,22VFS@171550|Rikenellaceae	976|Bacteroidetes	L	DNA methylase	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
k59_588852_5	1121456.ATVA01000014_gene632	4.55e-90	289.0	COG1783@1|root,COG1783@2|Bacteria,1RAGC@1224|Proteobacteria,42Z29@68525|delta/epsilon subdivisions,2WTUP@28221|Deltaproteobacteria,2MCJK@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	phage Terminase large subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_588852_6	1414738.V5URC1_9CAUD	9.1e-22	95.5	4QAKE@10239|Viruses,4QUP7@35237|dsDNA viruses  no RNA stage,4QPCE@28883|Caudovirales,4QNBJ@10744|Podoviridae	10744|Podoviridae	S	endonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_177626_1	709032.Sulku_2610	1.95e-29	115.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,42M9Q@68525|delta/epsilon subdivisions,2YMEW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC	napA	-	-	ko:K02567	ko00910,ko01120,map00910,map01120	M00529,M00530	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
k59_177626_2	709032.Sulku_2611	1.35e-65	207.0	COG0437@1|root,COG0437@2|Bacteria,1N9WY@1224|Proteobacteria,42MXM@68525|delta/epsilon subdivisions,2YMAD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	TIGRFAM MauM NapG family ferredoxin-type protein	napG	-	-	ko:K02573	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_4,Fer4_7
k59_353789_1	709032.Sulku_0881	3.34e-140	417.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2YMAI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k59_823782_1	159087.Daro_0742	1.04e-126	367.0	COG0455@1|root,COG0455@2|Bacteria,1R8IW@1224|Proteobacteria,2VRTK@28216|Betaproteobacteria,2KUF4@206389|Rhodocyclales	206389|Rhodocyclales	D	Belongs to the ParA family	-	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	CbiA
k59_1528541_1	709032.Sulku_2493	1.8e-78	240.0	COG1413@1|root,COG1413@2|Bacteria,1NMDT@1224|Proteobacteria,42WYR@68525|delta/epsilon subdivisions,2YQSX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1528541_2	1249480.B649_11555	6.65e-65	199.0	2AJ5V@1|root,319QG@2|Bacteria,1Q3K7@1224|Proteobacteria,42XFR@68525|delta/epsilon subdivisions,2YQU7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1528541_3	1249480.B649_11560	5.86e-43	149.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,42NR0@68525|delta/epsilon subdivisions,2YRAH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	ParA
k59_1058277_1	709032.Sulku_1154	1.37e-50	173.0	COG4773@1|root,COG4773@2|Bacteria,1R8BS@1224|Proteobacteria,42M7T@68525|delta/epsilon subdivisions,2YS9H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	PFAM outer membrane porin	-	-	-	-	-	-	-	-	-	-	-	-	OprD
k59_1176137_1	395494.Galf_2490	2.96e-59	196.0	COG0845@1|root,COG0845@2|Bacteria,1MV1R@1224|Proteobacteria,2VHJC@28216|Betaproteobacteria,44WE6@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23
k59_941238_1	387093.SUN_0907	5.13e-122	387.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2YMRQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_60559_3	1537917.JU82_01075	4.07e-25	97.1	COG0666@1|root,COG0666@2|Bacteria,1Q2UY@1224|Proteobacteria,42WAJ@68525|delta/epsilon subdivisions,2YQKP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_4,Ank_5
k59_1704338_2	709032.Sulku_0004	1.72e-13	69.3	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1RGCV@1224|Proteobacteria,42M47@68525|delta/epsilon subdivisions,2YMRS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	(EAL) domain protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_1469129_1	1454004.AW11_02841	1.67e-86	263.0	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2VK14@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM Patatin	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
k59_1351840_2	1537917.JU82_00260	1.93e-28	106.0	COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,42R30@68525|delta/epsilon subdivisions,2YNU1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
k59_1822163_1	387093.SUN_0087	1.82e-100	298.0	COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,42NGR@68525|delta/epsilon subdivisions,2YMH4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
k59_1763056_1	1123269.NX02_23300	1.33e-06	55.8	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,2K2CT@204457|Sphingomonadales	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
k59_412801_1	159087.Daro_2003	1.46e-138	411.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,2VHFQ@28216|Betaproteobacteria,2KVUA@206389|Rhodocyclales	206389|Rhodocyclales	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
k59_1469154_1	1537917.JU82_03335	5.03e-105	306.0	COG0637@1|root,COG0637@2|Bacteria,1PUMZ@1224|Proteobacteria,42UAU@68525|delta/epsilon subdivisions,2YNG0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
k59_1176195_1	1249480.B649_00495	3.45e-239	673.0	COG0595@1|root,COG0595@2|Bacteria,1MUGV@1224|Proteobacteria,42M65@68525|delta/epsilon subdivisions,2YMJN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
k59_1528598_2	1537917.JU82_02150	6.74e-160	456.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,42M9E@68525|delta/epsilon subdivisions,2YMCM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
k59_1117079_1	1172190.M947_00045	2.24e-34	120.0	COG0721@1|root,COG0721@2|Bacteria,1Q61J@1224|Proteobacteria,42VIQ@68525|delta/epsilon subdivisions,2YQAY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
k59_1117079_2	1442598.JABW01000005_gene448	3.18e-29	108.0	COG1393@1|root,COG1393@2|Bacteria,1QDI7@1224|Proteobacteria,42U8X@68525|delta/epsilon subdivisions,2YPXC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	ArsC
k59_1704379_1	159087.Daro_1624	4.58e-144	420.0	COG0598@1|root,COG0598@2|Bacteria,1R7FC@1224|Proteobacteria,2VKBA@28216|Betaproteobacteria,2KUWR@206389|Rhodocyclales	206389|Rhodocyclales	P	Magnesium transport protein CorA	-	-	-	-	-	-	-	-	-	-	-	-	CorA
k59_177704_1	1165841.SULAR_07635	1.04e-18	85.5	COG0464@1|root,COG0464@2|Bacteria,1N4ZI@1224|Proteobacteria,42NGJ@68525|delta/epsilon subdivisions,2YMAX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	ATPase (AAA	-	-	-	-	-	-	-	-	-	-	-	-	AAA
k59_1704382_1	1173028.ANKO01000197_gene6080	2.38e-22	107.0	COG0642@1|root,COG2202@1|root,COG4191@1|root,COG5002@1|root,COG0642@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria,1G09B@1117|Cyanobacteria,1H82F@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,Response_reg
k59_1587132_1	1168067.JAGP01000001_gene738	8.16e-31	115.0	COG0835@1|root,COG0835@2|Bacteria,1RD1W@1224|Proteobacteria,1S26J@1236|Gammaproteobacteria,4614S@72273|Thiotrichales	72273|Thiotrichales	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
k59_1587132_2	857087.Metme_4060	3.23e-19	87.4	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1XDPM@135618|Methylococcales	135618|Methylococcales	T	Signal transduction histidine kinase, phosphotransfer (Hpt) region	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
k59_1351881_1	583345.Mmol_1825	1.3e-122	353.0	COG1668@1|root,COG1668@2|Bacteria,1QYVE@1224|Proteobacteria,2VWEI@28216|Betaproteobacteria,2KM8A@206350|Nitrosomonadales	206350|Nitrosomonadales	CP	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
k59_764746_1	709032.Sulku_1382	9.5e-115	342.0	2C3QV@1|root,2Z7YP@2|Bacteria,1MXAM@1224|Proteobacteria,42QBG@68525|delta/epsilon subdivisions,2YNTS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
k59_648204_2	1249480.B649_08995	1.1e-126	368.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42Q5V@68525|delta/epsilon subdivisions,2YND0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
k59_295255_1	1249480.B649_10855	1.26e-54	181.0	COG1426@1|root,COG1426@2|Bacteria,1Q33C@1224|Proteobacteria,42WQB@68525|delta/epsilon subdivisions,2YQFX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1528635_2	1537917.JU82_11835	1.02e-49	158.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,42V1U@68525|delta/epsilon subdivisions,2YPSE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Preprotein translocase	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
k59_353899_1	1283079.M1IPR7_9CAUD	1.17e-55	196.0	4QHMW@10239|Viruses,4QW8A@35237|dsDNA viruses  no RNA stage,4QRQV@28883|Caudovirales,4QP30@10744|Podoviridae	10744|Podoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_295271_2	1249480.B649_03405	2.51e-66	202.0	2BQIT@1|root,32JEK@2|Bacteria,1Q29V@1224|Proteobacteria,42V8T@68525|delta/epsilon subdivisions,2YQEB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_295271_3	1537917.JU82_09210	1.44e-42	154.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,42NGS@68525|delta/epsilon subdivisions,2YMZZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Ribonuclease	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB
k59_1410631_1	317025.Tcr_0610	3.65e-102	305.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,1RPBB@1236|Gammaproteobacteria,4603D@72273|Thiotrichales	72273|Thiotrichales	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
k59_605582_2	159087.Daro_1746	1.02e-68	213.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,2VH2E@28216|Betaproteobacteria,2KV64@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
k59_1602114_1	123899.JPQP01000001_gene1572	9.32e-79	258.0	COG0189@1|root,COG0769@1|root,COG0189@2|Bacteria,COG0769@2|Bacteria,1MVN2@1224|Proteobacteria,2WGKZ@28216|Betaproteobacteria,3T2VF@506|Alcaligenaceae	28216|Betaproteobacteria	F	cyanophycin	cphA2	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	CPSase_L_D2,Mur_ligase_C,Mur_ligase_M,RimK
k59_779214_2	1191523.MROS_0932	4.21e-14	69.7	2FCWF@1|root,344ZB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1546948_1	1304883.KI912532_gene782	2.23e-100	296.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,2VIVB@28216|Betaproteobacteria,2KUBC@206389|Rhodocyclales	206389|Rhodocyclales	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
k59_1546948_2	1219031.BBJR01000051_gene1482	2.38e-08	55.1	COG0421@1|root,COG1586@1|root,COG0421@2|Bacteria,COG1586@2|Bacteria,1MVV5@1224|Proteobacteria	1224|Proteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	GO:0003674,GO:0003824,GO:0004766,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0010487,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0043918,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	iECED1_1282.ECED1_0125,iPC815.YPO3411,iSDY_1059.SDY_0028	Spermine_synt_N,Spermine_synth
k59_252478_1	1249480.B649_00740	3.46e-60	191.0	COG3637@1|root,COG3637@2|Bacteria,1R3QN@1224|Proteobacteria,42Y1W@68525|delta/epsilon subdivisions,2YQU0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1840581_1	159087.Daro_0312	3.55e-127	398.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,2VHF3@28216|Betaproteobacteria,2KV0Q@206389|Rhodocyclales	206389|Rhodocyclales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_1661546_2	1249480.B649_03030	9.6e-103	307.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,42MMY@68525|delta/epsilon subdivisions,2YMDM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	dihydropteroate synthase	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
k59_898246_1	1165841.SULAR_09784	2.42e-74	229.0	COG5285@1|root,COG5285@2|Bacteria,1RC3C@1224|Proteobacteria,42R8R@68525|delta/epsilon subdivisions,2YNW8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG5285 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin	-	-	1.14.11.18	ko:K00477	ko04146,map04146	-	-	-	ko00000,ko00001,ko01000	-	-	-	PhyH
k59_898246_2	563040.Saut_1813	8.74e-26	97.1	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,42TPU@68525|delta/epsilon subdivisions,2YPES@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the thioredoxin family	trx2	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
k59_717750_1	204773.HEAR1946	6.72e-11	62.0	COG4726@1|root,COG4726@2|Bacteria,1N9C7@1224|Proteobacteria,2VWCD@28216|Betaproteobacteria,47525@75682|Oxalobacteraceae	28216|Betaproteobacteria	NU	Pilus assembly protein PilX	-	-	-	ko:K12286	-	-	-	-	ko00000,ko02044	-	-	-	-
k59_717750_2	159087.Daro_0886	2.28e-41	144.0	COG2165@1|root,COG2165@2|Bacteria,1RHHG@1224|Proteobacteria,2VT5N@28216|Betaproteobacteria,2KWMN@206389|Rhodocyclales	206389|Rhodocyclales	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K12285	-	-	-	-	ko00000,ko02044	-	-	-	N_methyl
k59_427705_1	398767.Glov_2666	3.77e-147	421.0	COG3677@1|root,COG3677@2|Bacteria,1NUTK@1224|Proteobacteria,43B02@68525|delta/epsilon subdivisions,2X6E5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Transposase zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_192182_1	572480.Arnit_0359	9.53e-68	238.0	COG0784@1|root,COG2198@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,43BU6@68525|delta/epsilon subdivisions,2YTGC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_9,Response_reg
k59_1019465_1	1537917.JU82_03705	4.2e-98	304.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2YMNT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_1546991_1	709032.Sulku_0059	1.66e-59	188.0	COG1714@1|root,COG1714@2|Bacteria,1N2TA@1224|Proteobacteria	1224|Proteobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
k59_840940_2	1348114.OM33_05835	5e-51	172.0	COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,1RMEG@1236|Gammaproteobacteria,2PZNC@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	iECH74115_1262.ECH74115_0142,iECSP_1301.ECSP_0134,iECs_1301.ECs0137,iG2583_1286.G2583_0137,iZ_1308.Z0144	Pantoate_ligase
k59_427727_1	216595.PFLU_5905	3.6e-12	64.3	COG0765@1|root,COG0765@2|Bacteria,1MVB6@1224|Proteobacteria,1RPGH@1236|Gammaproteobacteria,1YPT6@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	P	amino acid ABC transporter	yecS_3	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
k59_1430710_2	1537917.JU82_07685	1.11e-82	244.0	COG0727@1|root,COG0727@2|Bacteria,1N3F5@1224|Proteobacteria,42THI@68525|delta/epsilon subdivisions,2YPYY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Uncharacterised protein family (UPF0153)	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
k59_1430710_3	1537917.JU82_07690	3.71e-69	215.0	COG4123@1|root,COG4123@2|Bacteria,1RDSC@1224|Proteobacteria,42RIN@68525|delta/epsilon subdivisions,2YP8V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	MTS
k59_1548504_1	159087.Daro_3990	1.85e-78	263.0	COG0517@1|root,COG2203@1|root,COG3829@1|root,COG5001@1|root,COG0517@2|Bacteria,COG2203@2|Bacteria,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KUCK@206389|Rhodocyclales	206389|Rhodocyclales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CZB,EAL,GAF_2,GGDEF,PAS_4,PAS_9
k59_1721254_2	1537917.JU82_01925	8.5e-21	94.4	COG0790@1|root,COG0790@2|Bacteria,1NY7Z@1224|Proteobacteria,42T5I@68525|delta/epsilon subdivisions,2YPQ5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COG0790 FOG TPR repeat, SEL1 subfamily	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
k59_1368813_1	387093.SUN_2006	3.08e-37	133.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,42NCX@68525|delta/epsilon subdivisions,2YMK8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_1368813_2	387093.SUN_2005	1.28e-11	63.2	COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,42PJB@68525|delta/epsilon subdivisions,2YNGQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k59_1021200_1	159087.Daro_3963	2.19e-102	313.0	COG0223@1|root,COG1024@1|root,COG0223@2|Bacteria,COG1024@2|Bacteria,1MWYJ@1224|Proteobacteria,2VK38@28216|Betaproteobacteria,2KVS4@206389|Rhodocyclales	206389|Rhodocyclales	IJ	Formyl transferase, C-terminal domain	-	-	-	ko:K19640	-	-	-	-	ko00000,ko02022	-	-	-	ECH_1,Formyl_trans_C,Formyl_trans_N
k59_74450_1	1172190.M947_10870	1.34e-42	158.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42SS2@68525|delta/epsilon subdivisions,2YRAM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	CZB,MCPsignal
k59_1255427_1	1537917.JU82_10065	1.28e-51	177.0	COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,42RCJ@68525|delta/epsilon subdivisions,2YNX9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG4775 Outer membrane protein protective antigen OMA87	-	-	-	ko:K07278	-	-	-	-	ko00000,ko02000	1.B.33.2.4	-	-	Bac_surface_Ag,POTRA
k59_1255427_2	1537917.JU82_10060	2.3e-11	64.7	COG2911@1|root,COG2911@2|Bacteria,1PBYT@1224|Proteobacteria,42T65@68525|delta/epsilon subdivisions,2YPPD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
k59_1430762_1	709032.Sulku_2057	2.57e-85	275.0	COG1251@1|root,COG1740@1|root,COG1251@2|Bacteria,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,42PSD@68525|delta/epsilon subdivisions,2YNBA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	hydrogenase (NiFe) small subunit HydA	-	-	1.12.5.1	ko:K05927	-	-	-	-	ko00000,ko01000	-	-	-	Fer2_BFD,NiFe_hyd_SSU_C,Oxidored_q6,Pyr_redox_2
k59_899530_1	709032.Sulku_2414	1.88e-50	176.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,42MMR@68525|delta/epsilon subdivisions,2YMF0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	GM	Polysaccharide biosynthesis protein	pglF	-	4.2.1.135	ko:K15912	ko00520,map00520	-	-	-	ko00000,ko00001,ko01000	-	-	-	Polysacc_synt_2
k59_899530_2	1123514.KB905899_gene898	7.62e-27	110.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1RRTP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	GGDEF domain	-	GO:0003674,GO:0003824,GO:0005488,GO:0008144,GO:0016740,GO:0016772,GO:0016779,GO:0019825,GO:0020037,GO:0036094,GO:0042165,GO:0043167,GO:0043169,GO:0046906,GO:0048037,GO:0052621,GO:0070025,GO:0097159,GO:1901363	2.7.7.65	ko:K13069	-	-	R08057	-	ko00000,ko01000	-	-	-	GGDEF
k59_899533_2	1537917.JU82_03225	1.24e-125	381.0	COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2YMB9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	chemotaxis protein	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k59_1779658_1	1172190.M947_02895	6.85e-21	89.7	COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,42R55@68525|delta/epsilon subdivisions,2YNS0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
k59_1779658_2	387093.SUN_1451	3.16e-38	131.0	COG1734@1|root,COG1734@2|Bacteria,1NH80@1224|Proteobacteria,42WPX@68525|delta/epsilon subdivisions,2YQEX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG1734 DnaK suppressor protein	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
k59_1368866_1	159087.Daro_0829	3.04e-83	249.0	COG3707@1|root,COG3707@2|Bacteria,1MXDV@1224|Proteobacteria,2VSMR@28216|Betaproteobacteria,2KW1T@206389|Rhodocyclales	206389|Rhodocyclales	T	ANTAR	-	-	-	ko:K07183	-	-	-	-	ko00000,ko02022	-	-	-	ANTAR,Response_reg
k59_1368866_2	1121035.AUCH01000019_gene2897	5.64e-20	85.1	COG2138@1|root,COG2138@2|Bacteria,1N00J@1224|Proteobacteria,2VTXE@28216|Betaproteobacteria,2KX1I@206389|Rhodocyclales	206389|Rhodocyclales	S	cobalamin (vitamin B12) biosynthesis CbiX protein	-	-	4.99.1.3	ko:K03795	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiX
k59_429317_1	666681.M301_0439	1.19e-12	68.6	COG0484@1|root,COG0484@2|Bacteria,1Q629@1224|Proteobacteria,2VJ8G@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
k59_429317_2	1163617.SCD_n00969	6.65e-37	139.0	COG0484@1|root,COG0484@2|Bacteria,1MXM9@1224|Proteobacteria,2VPQ6@28216|Betaproteobacteria	28216|Betaproteobacteria	C	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII
k59_1842251_1	349521.HCH_00297	2.81e-75	240.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,1RMI2@1236|Gammaproteobacteria,1XHK6@135619|Oceanospirillales	135619|Oceanospirillales	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
k59_491086_1	1537917.JU82_02865	3.33e-87	277.0	COG4206@1|root,COG4206@2|Bacteria,1QUGQ@1224|Proteobacteria,42PHJ@68525|delta/epsilon subdivisions,2YNKV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_1487155_1	1165841.SULAR_01658	3.59e-45	149.0	COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,42V63@68525|delta/epsilon subdivisions,2YT0N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
k59_1487155_2	1165841.SULAR_01653	3.99e-22	90.5	2A1M6@1|root,30PVA@2|Bacteria,1QTJ9@1224|Proteobacteria,42VDW@68525|delta/epsilon subdivisions,2YQIZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
k59_959868_1	1165841.SULAR_03807	2.06e-48	166.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,42MZN@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Belongs to the RtcB family	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
k59_959868_2	1165841.SULAR_03812	3.15e-76	229.0	COG1371@1|root,COG1371@2|Bacteria,1N301@1224|Proteobacteria	1224|Proteobacteria	S	Archease protein family (MTH1598/TM1083)	-	-	-	-	-	-	-	-	-	-	-	-	Archease
k59_1021309_2	1249480.B649_05850	1.17e-100	294.0	COG1763@1|root,COG1763@2|Bacteria,1RD3Q@1224|Proteobacteria,42RZK@68525|delta/epsilon subdivisions,2YPCQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	molybdopterin-guanine dinucleotide biosynthesis protein	mobB	-	-	ko:K03753	-	-	-	-	ko00000	-	-	-	MobB
k59_668482_1	882378.RBRH_00380	2.11e-08	54.3	COG2151@1|root,COG2151@2|Bacteria,1RF3S@1224|Proteobacteria,2VQI0@28216|Betaproteobacteria,1KG6C@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Phenylacetic acid degradation	paaD	-	-	ko:K02612	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FeS_assembly_P
k59_668482_2	1304883.KI912532_gene236	1.18e-74	229.0	COG3396@1|root,COG3396@2|Bacteria,1MVYQ@1224|Proteobacteria,2VJ03@28216|Betaproteobacteria,2KW9B@206389|Rhodocyclales	206389|Rhodocyclales	S	Phenylacetic acid catabolic protein	paaC	-	1.14.13.149	ko:K02611	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
k59_1255544_1	1537917.JU82_01860	1.13e-39	138.0	COG1385@1|root,COG1385@2|Bacteria,1QDSD@1224|Proteobacteria,42S1W@68525|delta/epsilon subdivisions,2YP9M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
k59_1192393_1	317025.Tcr_1150	5.4e-53	190.0	COG2202@1|root,COG2203@1|root,COG5001@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,45ZZR@72273|Thiotrichales	72273|Thiotrichales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_9
k59_1548681_1	640081.Dsui_2758	5.98e-63	203.0	COG1092@1|root,COG1092@2|Bacteria,1R6GY@1224|Proteobacteria,2VNTR@28216|Betaproteobacteria,2KYCD@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the methyltransferase superfamily	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
k59_551397_1	1168067.JAGP01000001_gene42	5.09e-79	248.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,1RNCW@1236|Gammaproteobacteria,46026@72273|Thiotrichales	72273|Thiotrichales	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
k59_1430893_1	709032.Sulku_2269	1.4e-147	454.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2YMP9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5,RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_1779730_2	1121035.AUCH01000020_gene2653	7.89e-22	95.5	COG1317@1|root,COG1317@2|Bacteria,1NMQE@1224|Proteobacteria,2VSQ0@28216|Betaproteobacteria,2KWS2@206389|Rhodocyclales	206389|Rhodocyclales	N	Flagellar assembly protein FliH	-	-	-	ko:K02411	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliH
k59_1548692_2	1165841.SULAR_00300	3.86e-69	216.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,42PKA@68525|delta/epsilon subdivisions,2YP35@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the protein N5-glutamine methyltransferase family	hemK	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
k59_1255585_1	1249480.B649_10280	9.49e-48	169.0	COG4206@1|root,COG4206@2|Bacteria,1QUPS@1224|Proteobacteria,43CID@68525|delta/epsilon subdivisions,2YTCZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_1779748_1	1249480.B649_01365	1.26e-91	278.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,42N4K@68525|delta/epsilon subdivisions,2YMVY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	HI0933 family	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
k59_1721396_1	709032.Sulku_1555	1.42e-35	131.0	COG0810@1|root,COG0810@2|Bacteria,1PEYQ@1224|Proteobacteria,42WJI@68525|delta/epsilon subdivisions,2YQ9A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	TonB_2,TonB_C
k59_369296_1	1249480.B649_05600	2.9e-23	98.6	COG0791@1|root,COG0791@2|Bacteria,1R45H@1224|Proteobacteria,42NS0@68525|delta/epsilon subdivisions,2YN06@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,N_NLPC_P60,Peptidase_M15_4,SH3_6,SH3_7
k59_369296_2	709032.Sulku_0994	7.98e-44	144.0	COG1558@1|root,COG1558@2|Bacteria,1R09B@1224|Proteobacteria	1224|Proteobacteria	N	Flagellar basal body rod FlgEFG protein C-terminal	-	-	-	ko:K02388	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k59_1192424_1	709032.Sulku_0716	3.7e-136	400.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2YMIX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	ctsE	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
k59_1721407_1	572479.Hprae_1442	8.14e-24	102.0	COG2989@1|root,COG2989@2|Bacteria,1VU2X@1239|Firmicutes,24Y29@186801|Clostridia,3WBGT@53433|Halanaerobiales	186801|Clostridia	S	Peptidoglycan-binding domain 1 protein	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
k59_1721407_2	187272.Mlg_1034	4.92e-14	70.9	COG3108@1|root,COG3108@2|Bacteria,1MWW2@1224|Proteobacteria,1RS5K@1236|Gammaproteobacteria,1WXYD@135613|Chromatiales	135613|Chromatiales	S	Bacterial protein of unknown function (DUF882)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_2
k59_780999_1	1304883.KI912532_gene164	2.15e-32	118.0	COG1191@1|root,COG1191@2|Bacteria,1MWEU@1224|Proteobacteria,2VHR3@28216|Betaproteobacteria,2KUVX@206389|Rhodocyclales	206389|Rhodocyclales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes	fliA	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_780999_2	159087.Daro_0742	8.89e-73	226.0	COG0455@1|root,COG0455@2|Bacteria,1R8IW@1224|Proteobacteria,2VRTK@28216|Betaproteobacteria,2KUF4@206389|Rhodocyclales	206389|Rhodocyclales	D	Belongs to the ParA family	-	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	CbiA
k59_551468_2	1537917.JU82_11170	1.16e-80	250.0	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,42N01@68525|delta/epsilon subdivisions,2YMG2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
k59_1307537_1	1122138.AQUZ01000088_gene2362	4.51e-29	119.0	COG0488@1|root,COG0488@2|Bacteria,2GKBQ@201174|Actinobacteria,4DNB9@85009|Propionibacteriales	201174|Actinobacteria	S	ABC transporter	yjjK	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
k59_1779796_1	709032.Sulku_0494	4.7e-131	375.0	COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,42N4V@68525|delta/epsilon subdivisions,2YN04@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the pseudouridine synthase RluA family	rluA	-	5.4.99.23,5.4.99.24	ko:K06179,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
k59_1430994_1	497321.C664_16805	3.9e-82	263.0	COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,2VHVC@28216|Betaproteobacteria,2KUWV@206389|Rhodocyclales	206389|Rhodocyclales	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
k59_310050_1	317025.Tcr_1626	3.23e-108	321.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,1RMN0@1236|Gammaproteobacteria,4623F@72273|Thiotrichales	72273|Thiotrichales	O	Peptidase family M48	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
k59_310050_2	2340.JV46_16400	2.69e-22	92.8	COG3235@1|root,COG3235@2|Bacteria,1PS8W@1224|Proteobacteria,1SX3A@1236|Gammaproteobacteria,1JBA9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Cobalt uptake substrate-specific transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	CbiM
k59_668630_1	1040989.AWZU01000004_gene7072	2.83e-35	139.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,2TRVB@28211|Alphaproteobacteria,3JR8N@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,Methyltransf_23,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
k59_781074_2	1042209.HK44_000550	1.91e-11	67.0	COG1306@1|root,COG1306@2|Bacteria,1MWBY@1224|Proteobacteria,1RV3Z@1236|Gammaproteobacteria,1YTA5@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	S	Putative glycosyl hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4015
k59_369379_1	159087.Daro_0545	2.25e-58	182.0	2E4DA@1|root,33604@2|Bacteria,1NCA3@1224|Proteobacteria,2VWKE@28216|Betaproteobacteria,2KZUR@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_193700_1	1123502.AQXD01000003_gene1607	1.54e-56	195.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,1RNBF@1236|Gammaproteobacteria,1X3VD@135614|Xanthomonadales	135614|Xanthomonadales	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
k59_74662_1	1116472.MGMO_25c00370	3.01e-50	166.0	COG1871@1|root,COG1871@2|Bacteria,1RDDB@1224|Proteobacteria,1S41X@1236|Gammaproteobacteria,1XEGP@135618|Methylococcales	135618|Methylococcales	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	-	-	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
k59_1779867_2	929558.SMGD1_0904	3.63e-61	209.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2YMKB@29547|Epsilonproteobacteria	68525|delta/epsilon subdivisions	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
k59_781121_1	1168067.JAGP01000001_gene1352	3.9e-69	219.0	COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1N81M@1224|Proteobacteria,1RPS1@1236|Gammaproteobacteria,460ER@72273|Thiotrichales	72273|Thiotrichales	T	Chemotaxis protein	-	-	-	ko:K03415	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CheW,Response_reg
k59_1076754_1	436114.SYO3AOP1_0529	7.44e-110	326.0	COG1087@1|root,COG1087@2|Bacteria,2G3QB@200783|Aquificae	200783|Aquificae	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
k59_802638_1	1249480.B649_02780	1.18e-129	381.0	COG0642@1|root,COG0642@2|Bacteria,1N5IQ@1224|Proteobacteria,42M9P@68525|delta/epsilon subdivisions,2YN0U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	cprS	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
k59_90208_2	1537917.JU82_10705	7.45e-36	132.0	COG0457@1|root,COG0457@2|Bacteria,1MXK4@1224|Proteobacteria,42PK9@68525|delta/epsilon subdivisions,2YNXX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
k59_213533_1	709032.Sulku_0301	2.94e-80	242.0	2AIHQ@1|root,318ZM@2|Bacteria,1Q19H@1224|Proteobacteria,42T48@68525|delta/epsilon subdivisions,2YPGP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_213533_2	1249480.B649_01315	4.37e-55	176.0	COG3166@1|root,COG3166@2|Bacteria,1Q1VC@1224|Proteobacteria,42UGS@68525|delta/epsilon subdivisions,2YPY1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	PFAM Fimbrial assembly family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_90231_1	1249480.B649_07100	8.89e-154	445.0	COG4773@1|root,COG4773@2|Bacteria,1PP2I@1224|Proteobacteria,42WFP@68525|delta/epsilon subdivisions,2YQM1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Receptor	-	-	-	-	-	-	-	-	-	-	-	-	OprD
k59_1094449_1	159087.Daro_2999	3.02e-40	133.0	COG0254@1|root,COG0254@2|Bacteria,1MZ69@1224|Proteobacteria,2VW5V@28216|Betaproteobacteria,2KX6T@206389|Rhodocyclales	206389|Rhodocyclales	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
k59_1094449_2	1304883.KI912532_gene1950	4.62e-18	82.8	COG1807@1|root,COG1807@2|Bacteria,1PUE3@1224|Proteobacteria,2VHPU@28216|Betaproteobacteria,2KUEG@206389|Rhodocyclales	206389|Rhodocyclales	M	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
k59_802694_1	1304883.KI912532_gene1628	1.52e-92	275.0	COG5490@1|root,COG5490@2|Bacteria,1RJUA@1224|Proteobacteria,2VTPT@28216|Betaproteobacteria,2KWSY@206389|Rhodocyclales	206389|Rhodocyclales	S	Phasin protein	-	-	-	-	-	-	-	-	-	-	-	-	Phasin_2
k59_1324383_1	395494.Galf_2216	5.09e-89	281.0	COG4166@1|root,COG4166@2|Bacteria,1R87R@1224|Proteobacteria,2VKFJ@28216|Betaproteobacteria,44W8T@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	oppA	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
k59_980458_1	1165841.SULAR_06283	2.01e-120	357.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,42M0I@68525|delta/epsilon subdivisions,2YMV0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
k59_1863235_1	1121035.AUCH01000020_gene2642	1.06e-17	87.0	COG1345@1|root,COG1345@2|Bacteria,1MUVP@1224|Proteobacteria,2VHMK@28216|Betaproteobacteria,2KUJB@206389|Rhodocyclales	206389|Rhodocyclales	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	-	-	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_IN,FliD_C,FliD_N
k59_1681529_1	1249480.B649_09110	7.48e-74	223.0	COG3787@1|root,COG3787@2|Bacteria,1RH76@1224|Proteobacteria,42TS4@68525|delta/epsilon subdivisions,2YPWQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	cofactor binding	Cj1449c	-	-	ko:K09979	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
k59_1681529_2	1249480.B649_09115	7.8e-13	67.4	COG1168@1|root,COG1168@2|Bacteria,1MY33@1224|Proteobacteria,42M6F@68525|delta/epsilon subdivisions,2YMXE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Aminotransferase, class I	patB	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_1096239_2	1249480.B649_03910	4.19e-52	170.0	COG2062@1|root,COG2062@2|Bacteria,1N0FX@1224|Proteobacteria,42TJ0@68525|delta/epsilon subdivisions,2YPZ4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	phosphohistidine phosphatase, SixA	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
k59_1326742_1	1165841.SULAR_01608	7.95e-95	278.0	COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,43BC4@68525|delta/epsilon subdivisions,2YMGN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
k59_512089_1	1537917.JU82_04815	8.7e-216	602.0	COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,43DRR@68525|delta/epsilon subdivisions,2YMSV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	o-acetylhomoserine	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
k59_1454072_1	1537917.JU82_03040	7.83e-81	244.0	COG2836@1|root,COG2836@2|Bacteria,1RIGJ@1224|Proteobacteria,42Q44@68525|delta/epsilon subdivisions,2YNTJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
k59_1159376_1	709032.Sulku_2279	2.3e-78	240.0	COG3022@1|root,COG3022@2|Bacteria,1Q5IV@1224|Proteobacteria,42QYB@68525|delta/epsilon subdivisions,2YNY3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the UPF0246 family	-	-	-	ko:K09861	-	-	-	-	ko00000	-	-	-	H2O2_YaaD
k59_512097_1	717773.Thicy_1039	2.28e-48	161.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,1RMSY@1236|Gammaproteobacteria,460GU@72273|Thiotrichales	72273|Thiotrichales	H	riboflavin synthase, alpha	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
k59_1046287_1	1547445.LO80_08550	6.75e-18	81.6	COG1089@1|root,COG1089@2|Bacteria,1MUX0@1224|Proteobacteria,1RMIY@1236|Gammaproteobacteria,45ZX3@72273|Thiotrichales	72273|Thiotrichales	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
k59_1046287_2	990073.ATHU01000001_gene1029	1.11e-43	154.0	COG0451@1|root,COG0451@2|Bacteria,1MUGT@1224|Proteobacteria,42M12@68525|delta/epsilon subdivisions,2YNBD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
k59_1212102_2	90814.KL370891_gene1760	4.48e-38	129.0	COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,1SCH5@1236|Gammaproteobacteria,4613Z@72273|Thiotrichales	72273|Thiotrichales	K	regulatory protein, arsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
k59_734570_1	709032.Sulku_1451	2.45e-33	134.0	COG0515@1|root,COG0715@1|root,COG2199@1|root,COG0515@2|Bacteria,COG0715@2|Bacteria,COG2199@2|Bacteria,1RGCV@1224|Proteobacteria,42YM2@68525|delta/epsilon subdivisions,2YTAT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	ggdef domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
k59_1389410_1	159087.Daro_0168	3.02e-110	323.0	COG5473@1|root,COG5473@2|Bacteria,1N9UJ@1224|Proteobacteria,2VNM5@28216|Betaproteobacteria,2KWHK@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1326784_2	159087.Daro_4004	1.23e-78	247.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2VIYF@28216|Betaproteobacteria,2KU70@206389|Rhodocyclales	206389|Rhodocyclales	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	pccB	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
k59_512133_1	709032.Sulku_1100	1.31e-94	282.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,42RH7@68525|delta/epsilon subdivisions	1224|Proteobacteria	N	Flagellar motor protein	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
k59_34558_1	387092.NIS_0526	2.64e-44	159.0	COG3203@1|root,COG3203@2|Bacteria,1QVBP@1224|Proteobacteria,42M72@68525|delta/epsilon subdivisions,2YNNX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	outer membrane porin, OprD family	-	-	-	-	-	-	-	-	-	-	-	-	OprD
k59_692218_1	665942.HMPREF1022_01291	9.96e-36	139.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WIR4@28221|Deltaproteobacteria,2M7T3@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HAMP,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,Response_reg
k59_1096325_1	709032.Sulku_0557	5.48e-49	162.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,42N0I@68525|delta/epsilon subdivisions,2YMW1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
k59_1096325_2	1537917.JU82_03255	6e-49	160.0	COG1179@1|root,COG1179@2|Bacteria,1MWXR@1224|Proteobacteria,42PHC@68525|delta/epsilon subdivisions,2YNF2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	involved in molybdopterin and thiamine biosynthesis family 1	-	-	-	-	-	-	-	-	-	-	-	-	ThiF
k59_34562_1	1123368.AUIS01000024_gene943	1.21e-38	147.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,2NCGG@225057|Acidithiobacillales	225057|Acidithiobacillales	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_387017_1	1304883.KI912532_gene2408	1.92e-62	218.0	COG3501@1|root,COG4253@1|root,COG3501@2|Bacteria,COG4253@2|Bacteria,1MU7Q@1224|Proteobacteria,2VJDF@28216|Betaproteobacteria,2KUP9@206389|Rhodocyclales	206389|Rhodocyclales	S	Phage late control gene D protein (GPD)	-	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	DUF2345,Phage_GPD,T6SS_Vgr
k59_448528_1	709032.Sulku_0121	1.78e-110	343.0	COG5001@1|root,COG5001@2|Bacteria,1R4H0@1224|Proteobacteria,43CII@68525|delta/epsilon subdivisions,2YTD5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_34582_1	159087.Daro_2781	4.47e-93	276.0	COG1028@1|root,COG1028@2|Bacteria,1MW50@1224|Proteobacteria,2VIAR@28216|Betaproteobacteria,2KY1S@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	1.3.1.25	ko:K05783	ko00362,ko00364,ko00622,ko01100,ko01120,ko01220,map00362,map00364,map00622,map01100,map01120,map01220	M00551	R00813,R05292,R05293,R05309,R05314,R08111,R08112,R08113	RC00271,RC01326,RC01327	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short
k59_1046381_1	866536.Belba_2313	2.86e-47	170.0	COG1479@1|root,COG1479@2|Bacteria,4PA90@976|Bacteroidetes,47WZN@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1524)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1524,DUF262
k59_91671_1	1249480.B649_08195	9.02e-96	287.0	COG0457@1|root,COG0457@2|Bacteria,1N9AG@1224|Proteobacteria,42QUG@68525|delta/epsilon subdivisions,2YP2D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF3137)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3137
k59_271568_1	292415.Tbd_2520	5.3e-24	103.0	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,2VHKV@28216|Betaproteobacteria	28216|Betaproteobacteria	P	PFAM sodium calcium exchanger membrane region	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
k59_34612_1	1502770.JQMG01000001_gene870	3.4e-29	117.0	29Y2F@1|root,30JVD@2|Bacteria,1RAWX@1224|Proteobacteria,2VSM0@28216|Betaproteobacteria,2KKU0@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_734659_2	1249480.B649_03115	2.53e-165	482.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42YH8@68525|delta/epsilon subdivisions,2YRAU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
k59_1159491_1	349124.Hhal_0669	1.36e-11	69.3	COG0860@1|root,COG1388@1|root,COG0860@2|Bacteria,COG1388@2|Bacteria,1MUQK@1224|Proteobacteria,1RMP1@1236|Gammaproteobacteria,1WX8Q@135613|Chromatiales	135613|Chromatiales	M	Cell wall hydrolase autolysin	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,LysM
k59_1454207_2	1460635.JCM19038_3433	6.73e-34	127.0	2CWXD@1|root,32T0J@2|Bacteria,1VCVP@1239|Firmicutes,4IRUX@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1096381_1	1537917.JU82_11280	2.93e-73	235.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,42MPK@68525|delta/epsilon subdivisions,2YMFX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,SurA_N_3
k59_982984_1	1249480.B649_06650	8.31e-127	370.0	COG2199@1|root,COG2199@2|Bacteria,1Q4Z5@1224|Proteobacteria,4306K@68525|delta/epsilon subdivisions,2YRSF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	diguanylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_982984_2	1280954.HPO_05110	4.11e-12	63.2	2EH60@1|root,33AXW@2|Bacteria,1NGBT@1224|Proteobacteria,2VGFE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2798)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2798
k59_325217_1	1132855.KB913035_gene2146	1.86e-198	555.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,2VHBG@28216|Betaproteobacteria,2KKYP@206350|Nitrosomonadales	206350|Nitrosomonadales	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
k59_1389533_1	1165841.SULAR_07760	4.57e-104	308.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,42N2N@68525|delta/epsilon subdivisions,2YN3F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3708
k59_1389533_2	1165841.SULAR_07765	6.38e-22	92.8	COG0226@1|root,COG0226@2|Bacteria,1MUAZ@1224|Proteobacteria,42NM3@68525|delta/epsilon subdivisions,2YMMK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
k59_1681681_1	317025.Tcr_0750	1.4e-89	281.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,4608D@72273|Thiotrichales	72273|Thiotrichales	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k59_1572084_1	12336.Q331V6_CBCP	3.91e-39	138.0	4QAPV@10239|Viruses,4QV7H@35237|dsDNA viruses  no RNA stage,4QPC3@28883|Caudovirales,4QINS@10662|Myoviridae	10662|Myoviridae	S	DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_804857_1	883126.HMPREF9710_03970	4.47e-50	167.0	COG0618@1|root,COG0618@2|Bacteria,1MX0B@1224|Proteobacteria,2WI70@28216|Betaproteobacteria	28216|Betaproteobacteria	S	3'(2'),5'-bisphosphate nucleotidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1681695_1	1304883.KI912532_gene2223	1.36e-88	261.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,2VSRT@28216|Betaproteobacteria,2KWCE@206389|Rhodocyclales	206389|Rhodocyclales	J	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
k59_629867_1	1537917.JU82_10725	6.39e-50	168.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Beta_helix,Big_2,Flagellin_C,Flagellin_N,VWA,VWA_2
k59_629867_2	1537917.JU82_10730	8.51e-35	134.0	COG1729@1|root,COG1729@2|Bacteria,1R162@1224|Proteobacteria,43D7I@68525|delta/epsilon subdivisions,2YTGX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	-
k59_91724_1	709032.Sulku_1223	1.56e-19	87.8	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,42M9I@68525|delta/epsilon subdivisions,2YNRH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	general secretion pathway protein D	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
k59_91724_2	709032.Sulku_1224	5.32e-28	113.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2YMIX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE
k59_919016_2	178901.AmDm5_0593	1.22e-07	54.3	COG0463@1|root,COG0463@2|Bacteria,1N840@1224|Proteobacteria,2U7FP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_983041_1	583345.Mmol_1005	3.28e-44	148.0	COG3749@1|root,COG3749@2|Bacteria,1RJR9@1224|Proteobacteria,2VSQB@28216|Betaproteobacteria,2KKUK@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Bacterial protein of unknown function (DUF934)	-	-	-	-	-	-	-	-	-	-	-	-	DUF934
k59_983041_2	1502770.JQMG01000001_gene2115	2.81e-57	191.0	COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,2VIYX@28216|Betaproteobacteria,2KM3I@206350|Nitrosomonadales	206350|Nitrosomonadales	P	PFAM nitrite and sulphite reductase 4Fe-4S	-	-	1.8.1.2	ko:K00381	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
k59_215785_1	1120999.JONM01000011_gene1638	1.95e-37	139.0	COG3391@1|root,COG3391@2|Bacteria,1PX3W@1224|Proteobacteria,2W0YQ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
k59_215785_2	756067.MicvaDRAFT_4886	1.38e-11	65.9	COG0515@1|root,COG2203@1|root,COG2208@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,COG3899@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,Pkinase,SpoIIE
k59_1327000_1	709032.Sulku_0910	4.48e-28	106.0	COG0693@1|root,COG0693@2|Bacteria,1N7T2@1224|Proteobacteria,42RGX@68525|delta/epsilon subdivisions,2YPA8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	TIGRFAM DJ-1 family protein	thiJ	-	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
k59_215796_1	1249480.B649_04105	5.87e-162	461.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,42MHH@68525|delta/epsilon subdivisions,2YMRT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_1505378_1	585394.RHOM_00700	2.93e-78	244.0	COG0037@1|root,COG0037@2|Bacteria,1V1S0@1239|Firmicutes,24BSC@186801|Clostridia	186801|Clostridia	D	tRNA processing	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1623438_1	545276.KB898726_gene921	4.99e-32	115.0	COG2350@1|root,COG2350@2|Bacteria,1MZ9Z@1224|Proteobacteria,1S8UC@1236|Gammaproteobacteria,1WYXH@135613|Chromatiales	135613|Chromatiales	S	PFAM YCII-related	-	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
k59_1623438_2	1121943.KB899989_gene3486	1.59e-09	57.8	COG2917@1|root,COG2917@2|Bacteria,1NWIZ@1224|Proteobacteria,1RQAB@1236|Gammaproteobacteria,1XJ5X@135619|Oceanospirillales	135619|Oceanospirillales	D	probably involved in intracellular septation	ispZ	-	-	ko:K06190	-	-	-	-	ko00000	-	-	-	IspA
k59_1623460_1	929558.SMGD1_0378	2.71e-45	167.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2YMB9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	chemotaxis protein	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
k59_215841_1	749222.Nitsa_1401	6.78e-91	272.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,42REQ@68525|delta/epsilon subdivisions,2YSQU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	-
k59_512312_1	1537917.JU82_08650	5.02e-137	397.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,42M8P@68525|delta/epsilon subdivisions,2YN6C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	peptidase U32 family	prtC	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
k59_1505433_1	159087.Daro_3393	5.96e-153	438.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,2VHZN@28216|Betaproteobacteria,2KUKJ@206389|Rhodocyclales	206389|Rhodocyclales	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
k59_1212370_1	159087.Daro_3921	2.59e-57	193.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,2VHS3@28216|Betaproteobacteria,2KV81@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
k59_1212370_2	159087.Daro_3922	4.56e-28	111.0	COG3338@1|root,COG3338@2|Bacteria,1PEA6@1224|Proteobacteria,2VI5K@28216|Betaproteobacteria,2KUD9@206389|Rhodocyclales	206389|Rhodocyclales	P	carbonic anhydrase	ecaA	-	4.2.1.1	ko:K01674	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Carb_anhydrase
k59_325411_1	387093.SUN_1904	1.09e-56	199.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2YMJS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,NIT,Response_reg
k59_1623522_1	1249480.B649_08130	7.27e-93	295.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42UBD@68525|delta/epsilon subdivisions,2YRGP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	7TM diverse intracellular signalling	-	-	-	ko:K20971	ko02025,map02025	-	-	-	ko00000,ko00001,ko01001,ko02022	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c
k59_34815_1	709032.Sulku_1394	1.22e-100	317.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2YMQV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_1279373_1	118005.AWNK01000003_gene2316	7.09e-95	286.0	COG1089@1|root,COG1089@2|Bacteria	2|Bacteria	M	GDP-mannose 4,6-dehydratase activity	gmd	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008446,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
k59_1046566_1	1168034.FH5T_19635	2.1e-87	278.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NETS@976|Bacteroidetes,2FNBA@200643|Bacteroidia	976|Bacteroidetes	EU	Peptidase, S9A B C family, catalytic domain protein	dpp	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
k59_1389682_1	1121035.AUCH01000003_gene1229	1.91e-33	117.0	2EMHW@1|root,33F6H@2|Bacteria,1NH05@1224|Proteobacteria,2VYV6@28216|Betaproteobacteria,2KXHG@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1212404_1	1172190.M947_00885	9.76e-12	63.5	2AJ5D@1|root,319PZ@2|Bacteria,1Q3HS@1224|Proteobacteria,42XCD@68525|delta/epsilon subdivisions,2YQQ3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Chemotaxis phosphatase CheX	-	-	-	-	-	-	-	-	-	-	-	-	CheX
k59_1279387_1	1249480.B649_06995	1.08e-114	339.0	COG2710@1|root,COG2710@2|Bacteria,1MWSX@1224|Proteobacteria,42P89@68525|delta/epsilon subdivisions,2YN9D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the NifD NifK NifE NifN family	-	-	-	ko:K02592	-	-	-	-	ko00000	-	-	-	Oxidored_nitro
k59_215916_1	1249480.B649_11780	3.73e-155	456.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2YN94@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
k59_1389695_1	317619.ANKN01000066_gene2802	4.07e-54	192.0	COG5001@1|root,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria	1117|Cyanobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,FHA,GAF,GGDEF,PAS_9
k59_858631_1	709032.Sulku_1445	2.72e-65	201.0	COG2346@1|root,COG2346@2|Bacteria,1Q196@1224|Proteobacteria,42T3P@68525|delta/epsilon subdivisions,2YPP7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COGs COG2346 Truncated hemoglobins	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
k59_1176849_2	563040.Saut_0369	1.11e-52	175.0	COG0697@1|root,COG0697@2|Bacteria,1MZXM@1224|Proteobacteria,42ME7@68525|delta/epsilon subdivisions,2YMBW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EG	membrane	-	-	-	ko:K15270	-	-	-	-	ko00000,ko02000	2.A.7.3.7	-	-	EamA
k59_1822868_1	134676.ACPL_6108	7.31e-09	55.8	COG0439@1|root,COG1984@1|root,COG2049@1|root,COG0439@2|Bacteria,COG1984@2|Bacteria,COG2049@2|Bacteria,2I2S0@201174|Actinobacteria,4D8KW@85008|Micromonosporales	201174|Actinobacteria	I	Biotin carboxylase	uahA	-	6.3.4.14,6.3.4.6,6.4.1.2,6.4.1.3	ko:K01941,ko:K01961,ko:K01965	ko00061,ko00220,ko00280,ko00620,ko00630,ko00640,ko00720,ko00791,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00220,map00280,map00620,map00630,map00640,map00720,map00791,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00373,M00376,M00741	R00742,R00774,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00378,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,CT_A_B,CT_C_D
k59_1822868_2	159087.Daro_4004	1.32e-77	244.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2VIYF@28216|Betaproteobacteria,2KU70@206389|Rhodocyclales	206389|Rhodocyclales	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	pccB	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
k59_237353_1	1249480.B649_06370	6.55e-18	81.3	COG1261@1|root,COG1261@2|Bacteria,1Q3ZV@1224|Proteobacteria,42Y1K@68525|delta/epsilon subdivisions,2YQRI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Chaperone for flagella basal body P-ring formation	flgA	-	-	ko:K02386	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	ChapFlgA
k59_237353_2	1249480.B649_06375	4.74e-65	201.0	COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,42QXP@68525|delta/epsilon subdivisions,2YPJE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
k59_706604_1	159087.Daro_3527	1.55e-139	404.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,2VHQM@28216|Betaproteobacteria,2KU9F@206389|Rhodocyclales	206389|Rhodocyclales	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
k59_1822883_1	709032.Sulku_0172	4.51e-14	70.1	COG4969@1|root,COG4969@2|Bacteria	2|Bacteria	NU	cell adhesion	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin
k59_119967_1	580332.Slit_2226	1.36e-32	129.0	COG2199@1|root,COG2202@1|root,COG5000@1|root,COG2199@2|Bacteria,COG2202@2|Bacteria,COG5000@2|Bacteria,1NWNJ@1224|Proteobacteria,2WHI5@28216|Betaproteobacteria	28216|Betaproteobacteria	T	PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_3,PAS_9
k59_472387_1	709032.Sulku_0488	5.3e-105	322.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,42NN7@68525|delta/epsilon subdivisions,2YMKH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
k59_1646138_1	159087.Daro_0666	2.25e-99	309.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,2VIYB@28216|Betaproteobacteria,2KVTV@206389|Rhodocyclales	206389|Rhodocyclales	C	Malic enzyme	-	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
k59_1530191_2	1537917.JU82_08905	8.21e-35	133.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2YMW5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,TarH,dCache_2,sCache_2
k59_1764400_1	1122135.KB893135_gene973	3.2e-99	298.0	COG0477@1|root,COG2814@2|Bacteria,1MXPM@1224|Proteobacteria,2TSB9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
k59_1236303_1	1249480.B649_06995	1.54e-160	458.0	COG2710@1|root,COG2710@2|Bacteria,1MWSX@1224|Proteobacteria,42P89@68525|delta/epsilon subdivisions,2YN9D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the NifD NifK NifE NifN family	-	-	-	ko:K02592	-	-	-	-	ko00000	-	-	-	Oxidored_nitro
k59_1705674_1	583345.Mmol_1865	1.95e-116	344.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,2VHQM@28216|Betaproteobacteria,2KKNW@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
k59_1530247_1	1249480.B649_04790	1.43e-44	151.0	COG1639@1|root,COG1639@2|Bacteria,1RAH3@1224|Proteobacteria,42PRF@68525|delta/epsilon subdivisions,2YNUX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Signal transduction protein	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_1530247_2	1249480.B649_04785	1.56e-52	183.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,42M4I@68525|delta/epsilon subdivisions,2YMFT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_1823885_1	1304883.KI912532_gene2335	3.79e-50	171.0	COG0642@1|root,COG2205@2|Bacteria,1MUAK@1224|Proteobacteria,2VJ6W@28216|Betaproteobacteria,2KUEB@206389|Rhodocyclales	206389|Rhodocyclales	T	Periplasmic domain of Sensor histidine kinase RisS	-	-	2.7.13.3	ko:K07638	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,RisS_PPD
k59_1823885_2	159087.Daro_1980	3.83e-20	85.9	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,2VI6B@28216|Betaproteobacteria,2KUNC@206389|Rhodocyclales	206389|Rhodocyclales	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	ompR	-	-	ko:K02483,ko:K07659	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_1001420_1	1165841.SULAR_08662	3.13e-113	328.0	COG0461@1|root,COG0461@2|Bacteria,1RIC5@1224|Proteobacteria,42M91@68525|delta/epsilon subdivisions,2YMTS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
k59_1001420_2	387093.SUN_0036	1.05e-74	227.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,42NAA@68525|delta/epsilon subdivisions,2YMYI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
k59_1236340_1	1123487.KB892835_gene3522	5.04e-44	154.0	COG0820@1|root,COG0820@2|Bacteria,1Q0HH@1224|Proteobacteria,2VMGJ@28216|Betaproteobacteria,2KV68@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the radical SAM superfamily. RlmN family	-	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
k59_1236340_2	1109445.AGSX01000067_gene1387	4.45e-14	72.4	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1Z2AC@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	T	COG2202 FOG PAS PAC domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_9,Reg_prop,Y_Y_Y
k59_883811_1	1537917.JU82_11315	1.13e-160	459.0	COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,42P1M@68525|delta/epsilon subdivisions,2YN96@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Peptidase M48	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
k59_238119_1	1537917.JU82_03175	3.31e-88	266.0	COG1847@1|root,COG1847@2|Bacteria,1RB1P@1224|Proteobacteria,42QYV@68525|delta/epsilon subdivisions,2YNW5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Jag_N	-	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N
k59_1764440_1	709032.Sulku_1408	1.06e-143	420.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,42N7A@68525|delta/epsilon subdivisions,2YMRE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	lytic murein transglycosylase	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
k59_765851_1	709032.Sulku_2207	1.09e-17	81.3	COG5002@1|root,COG5002@2|Bacteria,1QZ29@1224|Proteobacteria,43CEG@68525|delta/epsilon subdivisions,2YTC2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_765851_2	709032.Sulku_2206	1.07e-83	251.0	COG0745@1|root,COG0745@2|Bacteria,1RA00@1224|Proteobacteria,43AME@68525|delta/epsilon subdivisions,2YT20@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_296397_1	688245.CtCNB1_4735	4.61e-15	76.3	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,2VH3W@28216|Betaproteobacteria,4A9WF@80864|Comamonadaceae	28216|Betaproteobacteria	LU	DNA protecting protein DprA	smf	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
k59_296397_2	1454004.AW11_02678	7.88e-35	131.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,2VHUF@28216|Betaproteobacteria,1KPP8@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	L	DNA topoisomerase III	topB	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	SWIB,Topoisom_bac,Toprim,Toprim_Crpt
k59_649905_1	1123326.JFBL01000001_gene1279	9.13e-22	86.7	COG5554@1|root,COG5554@2|Bacteria,1Q3JU@1224|Proteobacteria,42XF5@68525|delta/epsilon subdivisions,2YQVJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	nitrogen fixation protein FixT	-	-	-	ko:K02593	-	-	-	-	ko00000	-	-	-	NifT
k59_649905_2	709032.Sulku_1007	1.46e-19	89.4	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,42M81@68525|delta/epsilon subdivisions,2YMTF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_532426_1	159087.Daro_0264	3.5e-57	182.0	COG2197@1|root,COG2197@2|Bacteria,1P4TD@1224|Proteobacteria,2VMX4@28216|Betaproteobacteria,2KW82@206389|Rhodocyclales	206389|Rhodocyclales	K	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_532426_2	1304883.KI912532_gene527	1.17e-62	196.0	2EDY7@1|root,337T3@2|Bacteria,1RKSZ@1224|Proteobacteria,2VTSJ@28216|Betaproteobacteria,2KWV4@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1470558_1	1165841.SULAR_09224	2.24e-126	365.0	COG2116@1|root,COG2116@2|Bacteria,1MU0W@1224|Proteobacteria,42Q39@68525|delta/epsilon subdivisions,2YTRX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Formate/nitrite transporter	-	-	-	ko:K21993	-	-	-	-	ko00000,ko02000	1.A.16.2	-	-	Form_Nir_trans
k59_942879_1	159087.Daro_1004	3.18e-26	100.0	COG3038@1|root,COG3038@2|Bacteria,1MZ7X@1224|Proteobacteria,2VV6S@28216|Betaproteobacteria,2KX4W@206389|Rhodocyclales	206389|Rhodocyclales	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
k59_942879_2	159087.Daro_1003	1.6e-22	99.4	COG3391@1|root,COG3391@2|Bacteria,1P862@1224|Proteobacteria,2VM1W@28216|Betaproteobacteria,2KXH9@206389|Rhodocyclales	206389|Rhodocyclales	S	40-residue YVTN family beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
k59_1236403_1	640081.Dsui_1372	2.84e-140	416.0	COG0840@1|root,COG4564@1|root,COG0840@2|Bacteria,COG4564@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,2KUJI@206389|Rhodocyclales	206389|Rhodocyclales	NT	Methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,sCache_2
k59_1823959_2	159087.Daro_0320	6.58e-93	274.0	COG0088@1|root,COG0088@2|Bacteria,1MXPF@1224|Proteobacteria,2VHS6@28216|Betaproteobacteria,2KVFP@206389|Rhodocyclales	206389|Rhodocyclales	J	50S ribosomal protein L4	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
k59_1764481_1	1537917.JU82_06810	1.16e-222	639.0	COG0835@1|root,COG0835@2|Bacteria,1QVCF@1224|Proteobacteria,42M0F@68525|delta/epsilon subdivisions,2YNAP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	PFAM CheW domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CheW,dCache_1
k59_4502_1	1485545.JQLW01000005_gene847	9.55e-25	103.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria	1224|Proteobacteria	EGP	Major facilitator Superfamily	yajR	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
k59_4502_2	1165841.SULAR_10134	5.35e-115	332.0	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,42NGT@68525|delta/epsilon subdivisions,2YN0R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
k59_1059669_1	697282.Mettu_3976	3.65e-31	121.0	COG1140@1|root,COG1140@2|Bacteria,1QZP4@1224|Proteobacteria	1224|Proteobacteria	C	4Fe-4S dicluster domain	-	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	ko:K16965,ko:K17051	ko00920,map00920	-	R09500	RC02555	ko00000,ko00001,ko02000	5.A.3.8	-	-	Fer4_11,Nitr_red_bet_C
k59_1059669_2	1123368.AUIS01000008_gene2174	2.61e-69	223.0	COG1140@1|root,COG1140@2|Bacteria,1MW9Q@1224|Proteobacteria,1RNMJ@1236|Gammaproteobacteria,2NBX1@225057|Acidithiobacillales	225057|Acidithiobacillales	C	Respiratory nitrate reductase beta C-terminal	-	-	1.7.5.1	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Fer4_11,Nitr_red_bet_C
k59_355284_1	709032.Sulku_1186	7.9e-251	706.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,42N4X@68525|delta/epsilon subdivisions,2YMTD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Belongs to the FtsK SpoIIIE SftA family	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
k59_1001512_2	1323663.AROI01000035_gene1362	1.99e-61	195.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,1RP6D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	rve,rve_3
k59_1001520_1	159087.Daro_2186	8.12e-110	322.0	COG2885@1|root,COG2885@2|Bacteria,1MWHF@1224|Proteobacteria,2VIJS@28216|Betaproteobacteria,2KYGK@206389|Rhodocyclales	206389|Rhodocyclales	M	OmpA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA
k59_883908_1	177439.DPPB05	3.05e-13	68.6	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,42RS8@68525|delta/epsilon subdivisions,2X5QK@28221|Deltaproteobacteria,2MMIZ@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
k59_649982_1	1249480.B649_04270	1.51e-207	579.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,42P35@68525|delta/epsilon subdivisions,2YN2K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	iIT341.HP0867	LpxB
k59_1059716_1	709032.Sulku_0324	3.73e-206	604.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2YMJS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,NIT,Response_reg
k59_1059717_1	387093.SUN_0384	1.69e-167	489.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2YMHD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA helicase	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_1705817_1	709032.Sulku_0903	5.88e-104	315.0	COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,42NTK@68525|delta/epsilon subdivisions,2YNFT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the UPF0061 (SELO) family	-	-	-	-	-	-	-	-	-	-	-	-	UPF0061
k59_1470652_1	159087.Daro_3851	3.38e-109	318.0	COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,2VIGI@28216|Betaproteobacteria,2KUAD@206389|Rhodocyclales	206389|Rhodocyclales	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
k59_1588650_1	709032.Sulku_1275	5.23e-55	180.0	COG0598@1|root,COG0598@2|Bacteria,1MWMP@1224|Proteobacteria,42KZB@68525|delta/epsilon subdivisions,2YN63@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
k59_1588650_2	195103.CPF_2426	4.11e-26	108.0	COG2183@1|root,COG2183@2|Bacteria,1TPFE@1239|Firmicutes,248P0@186801|Clostridia,36DQ1@31979|Clostridiaceae	186801|Clostridia	K	domain protein	yhgF	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
k59_1001550_1	1249480.B649_01215	1.55e-104	326.0	COG0457@1|root,COG0457@2|Bacteria,1QV1A@1224|Proteobacteria,42MIW@68525|delta/epsilon subdivisions,2YMDB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Paralysed flagella protein	pflA	-	-	-	-	-	-	-	-	-	-	-	TPR_21,TPR_6,TPR_8,YfiO
k59_1412284_1	709032.Sulku_0372	2.49e-16	71.2	COG0227@1|root,COG0227@2|Bacteria,1PTFN@1224|Proteobacteria,42V1S@68525|delta/epsilon subdivisions,2YQAP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
k59_473376_1	999141.GME_10356	9.16e-124	367.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,1RP4V@1236|Gammaproteobacteria,1XHRG@135619|Oceanospirillales	135619|Oceanospirillales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_532548_1	1537917.JU82_04270	1.67e-37	129.0	COG2983@1|root,COG2983@2|Bacteria,1RHMX@1224|Proteobacteria,42UC9@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Belongs to the UPF0260 family	MA20_15575	-	-	ko:K09160	-	-	-	-	ko00000	-	-	-	CxxCxxCC
k59_532548_2	709032.Sulku_1633	4.73e-66	213.0	COG2206@1|root,COG2206@2|Bacteria,1R53C@1224|Proteobacteria,42R7P@68525|delta/epsilon subdivisions,2YPRS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
k59_1764574_2	90813.JQMT01000001_gene676	7.04e-50	171.0	COG0644@1|root,COG0644@2|Bacteria,1MZVI@1224|Proteobacteria,1RMNS@1236|Gammaproteobacteria,461GV@72273|Thiotrichales	72273|Thiotrichales	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
k59_1412308_1	1537917.JU82_05855	7.96e-52	174.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,42QFD@68525|delta/epsilon subdivisions,2YND7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	FP	Ppx GppA	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
k59_1236550_1	709032.Sulku_1511	4.19e-112	349.0	COG2199@1|root,COG2200@1|root,COG3287@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,COG3287@2|Bacteria,1NQKX@1224|Proteobacteria,43DAG@68525|delta/epsilon subdivisions,2YTHK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,FIST,FIST_C,GGDEF,PAS_9
k59_1001583_2	1165841.SULAR_08252	6.67e-59	190.0	COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,42NWB@68525|delta/epsilon subdivisions,2YP3D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
k59_943022_1	1144325.PMI22_04714	4.51e-32	134.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	4HB_MCP_1,GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,dCache_1
k59_1470706_1	709032.Sulku_0032	1.27e-95	286.0	COG0614@1|root,COG0614@2|Bacteria,1MWVF@1224|Proteobacteria,42SMM@68525|delta/epsilon subdivisions,2YPJY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
k59_355391_2	1123517.JOMR01000001_gene679	7.71e-45	162.0	COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,1RMWX@1236|Gammaproteobacteria,460RM@72273|Thiotrichales	72273|Thiotrichales	N	Flagellar hook protein FlgE	-	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bb_rod,Flg_bbr_C
k59_943042_1	709032.Sulku_0755	2.18e-74	227.0	COG0711@1|root,COG0711@2|Bacteria,1Q9TP@1224|Proteobacteria,42U87@68525|delta/epsilon subdivisions,2YPT1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
k59_1705878_1	1537917.JU82_11565	1.52e-102	303.0	COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,42R60@68525|delta/epsilon subdivisions,2YNZM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_1705878_2	1537917.JU82_11560	1.93e-43	152.0	COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,42N49@68525|delta/epsilon subdivisions,2YND2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA
k59_4688_2	1249480.B649_02450	3.61e-20	90.9	COG0457@1|root,COG0457@2|Bacteria,1NRB9@1224|Proteobacteria,42W0K@68525|delta/epsilon subdivisions,2YQ9W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_2,TPR_8
k59_1177793_1	159087.Daro_4025	6.84e-110	321.0	COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,2VKXN@28216|Betaproteobacteria,2KUI2@206389|Rhodocyclales	206389|Rhodocyclales	S	membrane transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	TauE
k59_1588728_1	159087.Daro_3772	3.52e-37	139.0	COG4235@1|root,COG4235@2|Bacteria,1PE9I@1224|Proteobacteria,2W1Y3@28216|Betaproteobacteria	28216|Betaproteobacteria	O	cytochrome complex assembly	-	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	-
k59_4709_1	159087.Daro_0866	2.23e-115	360.0	COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,2VHX1@28216|Betaproteobacteria,2KUPN@206389|Rhodocyclales	206389|Rhodocyclales	NU	COG3170 Tfp pilus assembly protein FimV	-	-	-	ko:K08086	-	-	-	-	ko00000	-	-	-	LysM
k59_1236640_1	1537917.JU82_08270	1.99e-172	493.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,42MEU@68525|delta/epsilon subdivisions,2YMUF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
k59_1119022_2	1249480.B649_08320	0.000175	42.7	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,42M8S@68525|delta/epsilon subdivisions,2YNN2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
k59_1177817_2	1537917.JU82_06470	8.93e-74	226.0	COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,42TJ2@68525|delta/epsilon subdivisions,2YPJ2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
k59_120995_1	1304883.KI912532_gene1696	2.82e-120	373.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VI3F@28216|Betaproteobacteria,2KUP6@206389|Rhodocyclales	206389|Rhodocyclales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_825678_1	709032.Sulku_1931	7.37e-161	471.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,42M2T@68525|delta/epsilon subdivisions,2YMF5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	ATP-dependent CLP protease ATP-binding subunit	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_1530599_1	929558.SMGD1_0022	6.41e-07	57.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42NFY@68525|delta/epsilon subdivisions,2YR21@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_9
k59_296610_1	159087.Daro_1427	1.99e-119	356.0	COG0804@1|root,COG0804@2|Bacteria,1MU5P@1224|Proteobacteria,2VJYX@28216|Betaproteobacteria,2KUE8@206389|Rhodocyclales	206389|Rhodocyclales	E	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family	ureC	-	3.5.1.5	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Urease_alpha
k59_1824254_1	1502770.JQMG01000001_gene1967	5.08e-77	243.0	COG2982@1|root,COG2982@2|Bacteria,1PGCJ@1224|Proteobacteria,2W9UV@28216|Betaproteobacteria,2KNQC@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Protein involved in outer membrane biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	AsmA
k59_1059882_1	1304883.KI912532_gene1138	1.16e-116	347.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,2VJ07@28216|Betaproteobacteria,2KVNA@206389|Rhodocyclales	206389|Rhodocyclales	H	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis	ubiB	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
k59_1718995_1	1230343.CANP01000029_gene2267	6.85e-45	154.0	2C2YT@1|root,32RB7@2|Bacteria,1RJEN@1224|Proteobacteria,1SI88@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_17002_1	1454004.AW11_04059	4.14e-95	288.0	COG2170@1|root,COG2170@2|Bacteria,1MX4N@1224|Proteobacteria,2VK27@28216|Betaproteobacteria	28216|Betaproteobacteria	H	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	ybdK	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
k59_717307_1	717773.Thicy_0044	3.46e-135	405.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,45ZQ4@72273|Thiotrichales	72273|Thiotrichales	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
k59_1190536_1	159087.Daro_1544	1.06e-139	416.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VKIW@28216|Betaproteobacteria,2KV4W@206389|Rhodocyclales	206389|Rhodocyclales	I	AcyL-CoA dehydrogenase	fadE	-	-	ko:K06445	ko00071,ko01100,ko01212,map00071,map01100,map01212	M00087	R01175,R01279,R03777,R03857,R03990,R04751,R04754	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N,DUF1974
k59_136663_1	1123518.ARWI01000001_gene1345	1.58e-11	65.5	COG0715@1|root,COG0715@2|Bacteria,1NV0U@1224|Proteobacteria,1SNZC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	-
k59_136663_2	425104.Ssed_1381	3.37e-12	70.1	COG0642@1|root,COG0745@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,2QAMI@267890|Shewanellaceae	1236|Gammaproteobacteria	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS_4,PAS_9,Response_reg
k59_72957_1	709032.Sulku_0675	3.33e-136	403.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,42NGS@68525|delta/epsilon subdivisions,2YMZZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Ribonuclease	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB
k59_897716_1	395494.Galf_2302	4.63e-35	129.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,2VI4X@28216|Betaproteobacteria,44V6U@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
k59_897716_2	748280.NH8B_3105	1.6e-51	166.0	COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,2VQ5I@28216|Betaproteobacteria,2KR3P@206351|Neisseriales	206351|Neisseriales	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
k59_191648_1	580332.Slit_1193	5.43e-120	351.0	COG1176@1|root,COG1176@2|Bacteria,1MVGM@1224|Proteobacteria,2VHYC@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Pfam Binding-protein-dependent transport systems inner membrane component	potB	-	-	ko:K02054,ko:K11071	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11,3.A.1.11.1	-	-	BPD_transp_1
k59_1018735_2	709032.Sulku_0273	2.31e-32	117.0	COG1143@1|root,COG1143@2|Bacteria,1MZJF@1224|Proteobacteria,42M7S@68525|delta/epsilon subdivisions,2YNEG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
k59_550436_1	1304883.KI912532_gene1500	5.3e-58	183.0	COG0494@1|root,COG0494@2|Bacteria,1RH6N@1224|Proteobacteria,2VR3U@28216|Betaproteobacteria,2KWKI@206389|Rhodocyclales	206389|Rhodocyclales	L	NUDIX domain	-	-	3.6.1.67	ko:K08310	ko00790,map00790	M00126	R04638	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
k59_1486439_1	190650.CC_1009	4.79e-05	51.6	COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,2TSP0@28211|Alphaproteobacteria,2KH9Q@204458|Caulobacterales	204458|Caulobacterales	M	TIGRFAM type I secretion membrane fusion protein, HlyD family	-	-	-	ko:K12534	-	M00327	-	-	ko00000,ko00002,ko02000,ko02044	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3
k59_667562_1	709032.Sulku_1394	9.01e-105	327.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2YMQV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_1841395_1	339670.Bamb_6277	4.44e-94	295.0	COG3300@1|root,COG4191@1|root,COG3300@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VJGE@28216|Betaproteobacteria,1K5WB@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,MHYT,PAS,PAS_3,PAS_9,Response_reg,cNMP_binding
k59_1254638_1	367737.Abu_0664	1.57e-111	330.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42M4C@68525|delta/epsilon subdivisions,2YMFK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	wlaK	-	2.6.1.98	ko:K13017	ko00520,map00520	-	R10141	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
k59_1368146_1	709032.Sulku_2322	3.31e-44	148.0	2BTM2@1|root,32NTT@2|Bacteria,1Q3YE@1224|Proteobacteria,42XZF@68525|delta/epsilon subdivisions,2YQTV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1075776_1	709032.Sulku_0753	1.88e-79	243.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,42M8S@68525|delta/epsilon subdivisions,2YNN2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
k59_1191682_1	387093.SUN_1187	9.28e-118	357.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42N29@68525|delta/epsilon subdivisions,2YMFM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA helicase	rep	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_898892_2	1249480.B649_00290	3.27e-101	308.0	2DCNX@1|root,2ZESX@2|Bacteria,1QUV9@1224|Proteobacteria,43CMN@68525|delta/epsilon subdivisions,2YTEI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_368627_1	32024.JMTI01000049_gene1379	1.7e-07	50.8	2AIVC@1|root,319CK@2|Bacteria,1Q2BM@1224|Proteobacteria,42VCW@68525|delta/epsilon subdivisions,2YQF6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Family of unknown function (DUF4006)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4006
k59_368627_2	387093.SUN_0181	1.03e-147	423.0	COG2010@1|root,COG2010@2|Bacteria,1PDTK@1224|Proteobacteria,42N5Z@68525|delta/epsilon subdivisions,2YMTR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
k59_368627_3	1165841.SULAR_10044	5.13e-36	122.0	COG4736@1|root,COG4736@2|Bacteria,1QDIU@1224|Proteobacteria,42V2T@68525|delta/epsilon subdivisions,2YQ9S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	cytochrome c oxidase	ccoQ	-	-	ko:K00407	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixQ
k59_253154_1	1249480.B649_06130	6.86e-127	381.0	COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,42MY0@68525|delta/epsilon subdivisions,2YMT1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
k59_1779028_1	709032.Sulku_2270	1.47e-108	345.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,43DMZ@68525|delta/epsilon subdivisions,2YMMS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_550519_2	1249480.B649_06390	4.37e-153	437.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,42MG0@68525|delta/epsilon subdivisions,2YMII@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
k59_550535_1	1249627.D779_1567	2.54e-30	123.0	COG1639@1|root,COG2199@1|root,COG1639@2|Bacteria,COG3706@2|Bacteria,1MVRF@1224|Proteobacteria,1RPH0@1236|Gammaproteobacteria,1WYQ7@135613|Chromatiales	135613|Chromatiales	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HDOD
k59_138191_1	1123518.ARWI01000001_gene1505	1.54e-76	238.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,1RNWJ@1236|Gammaproteobacteria,45ZXS@72273|Thiotrichales	72273|Thiotrichales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
k59_138191_2	477228.YO5_14770	3.06e-50	174.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,1RP4V@1236|Gammaproteobacteria,1Z15X@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	iSbBS512_1146.SbBS512_E4187	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_368677_1	1038922.PflQ2_5688	1.41e-06	48.9	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
k59_368677_2	1123354.AUDR01000015_gene393	8.65e-63	206.0	COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,2VNEB@28216|Betaproteobacteria	28216|Betaproteobacteria	EGP	Drug resistance transporter Bcr CflA subfamily	-	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1
k59_1547866_1	1198232.CYCME_1656	1.17e-36	134.0	COG0560@1|root,COG0560@2|Bacteria,1MWA3@1224|Proteobacteria,1RNJE@1236|Gammaproteobacteria,45ZYN@72273|Thiotrichales	72273|Thiotrichales	E	phosphoserine phosphatase	-	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD,Hydrolase
k59_490481_1	296591.Bpro_3038	1.69e-70	227.0	COG2801@1|root,COG2801@2|Bacteria,1MXKK@1224|Proteobacteria,2VJQH@28216|Betaproteobacteria,4AHH6@80864|Comamonadaceae	28216|Betaproteobacteria	L	Integrase, catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_1430087_1	1537917.JU82_03100	2.69e-82	268.0	COG4581@1|root,COG4581@2|Bacteria,1MVD6@1224|Proteobacteria,42PR3@68525|delta/epsilon subdivisions,2YN2Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Mitochondrial degradasome RNA helicase subunit C terminal	-	-	3.6.4.13	ko:K17675	-	-	-	-	ko00000,ko01000,ko03029	-	-	-	Helicase_C,SUV3_C
k59_1430087_2	709032.Sulku_0064	1.35e-46	151.0	COG0607@1|root,COG0607@2|Bacteria,1Q1NN@1224|Proteobacteria,42U2F@68525|delta/epsilon subdivisions,2YQ1E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1254789_1	1356852.N008_15385	1.69e-08	60.1	COG3222@1|root,COG3222@2|Bacteria,4NP3Q@976|Bacteroidetes,47SG8@768503|Cytophagia	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2064)	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064
k59_18090_1	159087.Daro_0666	3.89e-101	315.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,2VIYB@28216|Betaproteobacteria,2KVTV@206389|Rhodocyclales	206389|Rhodocyclales	C	Malic enzyme	-	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
k59_1136553_1	387093.SUN_0044	3.22e-57	194.0	2C99Z@1|root,2Z9YV@2|Bacteria,1N0B7@1224|Proteobacteria,42P3M@68525|delta/epsilon subdivisions,2YMWY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF3373)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3373
k59_841775_1	1249480.B649_00030	1.02e-109	333.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria	1224|Proteobacteria	P	Receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_368756_1	387093.SUN_1965	5.42e-44	164.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42Z4X@68525|delta/epsilon subdivisions,2YRD8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_1720611_1	1165841.SULAR_10409	7.09e-124	362.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,42MWZ@68525|delta/epsilon subdivisions,2YMZW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
k59_1547996_1	582744.Msip34_2584	6e-110	348.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2VHYQ@28216|Betaproteobacteria,2KKBF@206350|Nitrosomonadales	206350|Nitrosomonadales	E	Vitamin B12 dependent methionine synthase activation	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
k59_1075973_1	159087.Daro_3216	4.11e-06	48.9	COG4796@1|root,COG4796@2|Bacteria,1QUY7@1224|Proteobacteria,2VJ8Z@28216|Betaproteobacteria,2KV4B@206389|Rhodocyclales	206389|Rhodocyclales	U	Bacterial type II/III secretion system short domain	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	STN,Secretin,Secretin_N
k59_1075973_2	1123393.KB891326_gene95	5.37e-17	80.9	COG1409@1|root,COG1409@2|Bacteria,1MV0H@1224|Proteobacteria,2WHIF@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
k59_959370_2	709032.Sulku_2164	5.61e-70	212.0	COG0537@1|root,COG0537@2|Bacteria,1MZVD@1224|Proteobacteria,42TMC@68525|delta/epsilon subdivisions,2YPSJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	FG	(HIT) family	-	-	-	-	-	-	-	-	-	-	-	-	HIT
k59_959370_3	709032.Sulku_2163	2.18e-37	134.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,42MU6@68525|delta/epsilon subdivisions,2YMMA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iIT341.HP0202	ACP_syn_III,ACP_syn_III_C
k59_1020597_1	395494.Galf_1244	2.54e-90	272.0	COG0421@1|root,COG0421@2|Bacteria,1RBWW@1224|Proteobacteria,2VK7S@28216|Betaproteobacteria,44V2F@713636|Nitrosomonadales	28216|Betaproteobacteria	E	PFAM Spermine synthase	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
k59_1020597_2	395494.Galf_0100	1.01e-17	80.9	COG2309@1|root,COG2309@2|Bacteria,1R4I5@1224|Proteobacteria,2VPND@28216|Betaproteobacteria	28216|Betaproteobacteria	E	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_428653_1	1537917.JU82_08465	1.02e-164	474.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,42M4S@68525|delta/epsilon subdivisions,2YM8Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	-	-	1.12.5.1	ko:K05922	-	-	-	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
k59_1430207_2	1537917.JU82_06820	1.32e-19	87.4	COG1315@1|root,COG1315@2|Bacteria,1R5P6@1224|Proteobacteria,42MAS@68525|delta/epsilon subdivisions,2YM7Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Flagellar Assembly Protein A	-	-	-	-	-	-	-	-	-	-	-	-	FapA
k59_1430213_1	153948.NAL212_0188	2e-34	132.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,2VHNX@28216|Betaproteobacteria,372XV@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
k59_1430213_2	580332.Slit_0015	1.2e-18	83.2	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,2VHHG@28216|Betaproteobacteria,44V14@713636|Nitrosomonadales	28216|Betaproteobacteria	C	SMART Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain	gapA	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k59_1076003_1	1537917.JU82_04590	3.14e-47	158.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,42NEA@68525|delta/epsilon subdivisions,2YN5P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
k59_1076003_2	709032.Sulku_0750	2.08e-36	131.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,42M3E@68525|delta/epsilon subdivisions,2YMQZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
k59_1841651_2	1279019.ARQK01000025_gene2387	1.36e-25	99.8	COG4706@1|root,COG4706@2|Bacteria,1RIH4@1224|Proteobacteria,1SFAZ@1236|Gammaproteobacteria,1WZCB@135613|Chromatiales	135613|Chromatiales	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_841839_1	709032.Sulku_1839	2.25e-176	504.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,42MEM@68525|delta/epsilon subdivisions,2YMWQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
k59_1486663_1	1537917.JU82_08680	8.6e-99	306.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42N29@68525|delta/epsilon subdivisions,2YMFM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA helicase	rep	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_1136648_1	709032.Sulku_0270	3.87e-195	563.0	COG1034@1|root,COG1034@2|Bacteria,1RCFT@1224|Proteobacteria,42NK4@68525|delta/epsilon subdivisions,2YNI6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G)	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4_10,Molybdopterin,NADH-G_4Fe-4S_3
k59_1254920_1	1266845.Q783_09225	1.61e-09	63.5	COG0835@1|root,COG0835@2|Bacteria,1VAMD@1239|Firmicutes,4HN1P@91061|Bacilli,27GP2@186828|Carnobacteriaceae	91061|Bacilli	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
k59_1548059_1	1165841.SULAR_07935	1.08e-125	369.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,42MGM@68525|delta/epsilon subdivisions,2YMUV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
k59_1841700_1	159087.Daro_3359	5.99e-67	210.0	COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria,2VJ1K@28216|Betaproteobacteria,2KUV6@206389|Rhodocyclales	206389|Rhodocyclales	T	(FHA) domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
k59_606615_1	395494.Galf_0030	6.01e-153	439.0	COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,2VHJK@28216|Betaproteobacteria,44VJU@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Belongs to the phosphoglycerate kinase family	pgk	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
k59_780321_1	159087.Daro_2868	1.04e-17	80.5	COG2301@1|root,COG2301@2|Bacteria,1Q91U@1224|Proteobacteria,2VJJY@28216|Betaproteobacteria,2KUFC@206389|Rhodocyclales	206389|Rhodocyclales	G	Belongs to the HpcH HpaI aldolase family	citE	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
k59_780321_2	159087.Daro_2867	1.35e-64	205.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,2VHC8@28216|Betaproteobacteria,2KUMR@206389|Rhodocyclales	206389|Rhodocyclales	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
k59_1430282_1	1537917.JU82_00170	5.72e-33	118.0	COG1871@1|root,COG1871@2|Bacteria,1RDDB@1224|Proteobacteria,43AIB@68525|delta/epsilon subdivisions,2YSY8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	-	-	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
k59_1430282_2	1537917.JU82_00165	1.67e-62	200.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,42M27@68525|delta/epsilon subdivisions,2YNWH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
k59_959438_1	159087.Daro_0338	9.88e-22	89.0	COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,2VRAK@28216|Betaproteobacteria,2KWAX@206389|Rhodocyclales	206389|Rhodocyclales	J	binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
k59_959438_2	159087.Daro_0339	6.5e-97	294.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,2VHQH@28216|Betaproteobacteria,2KVBF@206389|Rhodocyclales	206389|Rhodocyclales	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
k59_368853_1	1121403.AUCV01000124_gene2974	3.34e-53	179.0	COG2433@1|root,COG2433@2|Bacteria,1RE5Q@1224|Proteobacteria,42WSA@68525|delta/epsilon subdivisions,2WRPQ@28221|Deltaproteobacteria,2MMJ3@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,zf-IS66
k59_1841726_1	1205680.CAKO01000002_gene2466	3.41e-12	71.6	COG2207@1|root,COG2207@2|Bacteria,1R81X@1224|Proteobacteria,2TZJW@28211|Alphaproteobacteria,2JUGX@204441|Rhodospirillales	204441|Rhodospirillales	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding_2,HTH_18
k59_1136706_1	1304883.KI912532_gene1394	1.02e-156	441.0	COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,2VIIR@28216|Betaproteobacteria,2KU8Q@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
k59_606640_1	159087.Daro_2009	7e-115	336.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,2VH94@28216|Betaproteobacteria,2KVMS@206389|Rhodocyclales	206389|Rhodocyclales	OU	signal peptide peptidase	-	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
k59_368859_1	95619.PM1_0226745	4.79e-49	169.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,1RNIN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019897,GO:0019898,GO:0031224,GO:0031226,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033036,GO:0033365,GO:0034613,GO:0035639,GO:0036094,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
k59_1020733_1	1249480.B649_07315	2.21e-107	325.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42NK1@68525|delta/epsilon subdivisions,2YMHN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the AAA ATPase family	ftsH1	-	-	-	-	-	-	-	-	-	-	-	AAA,Peptidase_M41
k59_138464_1	709032.Sulku_0909	7.56e-120	343.0	COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,42N6H@68525|delta/epsilon subdivisions,2YM7S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
k59_1430324_2	1249480.B649_04690	4.37e-79	236.0	COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,42V63@68525|delta/epsilon subdivisions,2YT0N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
k59_490673_1	1249480.B649_00195	5.25e-26	103.0	COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,42PGR@68525|delta/epsilon subdivisions,2YRIC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PFAM metal-dependent phosphohydrolase HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
k59_490673_2	1537917.JU82_03095	2.29e-98	290.0	2AIM2@1|root,319HK@2|Bacteria,1Q2ST@1224|Proteobacteria,42W74@68525|delta/epsilon subdivisions,2YQAM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_384283_2	749222.Nitsa_1227	9.26e-28	112.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,42MUY@68525|delta/epsilon subdivisions,2YMZF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	PFAM peptidase M3A and M3B thimet oligopeptidase F	prlC	-	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
k59_508921_1	90814.KL370892_gene2326	9.41e-129	382.0	COG0699@1|root,COG0699@2|Bacteria,1MV59@1224|Proteobacteria,1RYGW@1236|Gammaproteobacteria,46275@72273|Thiotrichales	72273|Thiotrichales	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
k59_625893_1	709032.Sulku_1453	2.12e-15	72.8	COG1999@1|root,COG1999@2|Bacteria,1Q4TG@1224|Proteobacteria,42ZV5@68525|delta/epsilon subdivisions,2YRVW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
k59_625893_2	709032.Sulku_1452	6.9e-57	193.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YNJ4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_571653_2	827.JFJK01000005_gene1246	6.18e-16	79.3	COG0755@1|root,COG0755@2|Bacteria,1RG0A@1224|Proteobacteria,42N37@68525|delta/epsilon subdivisions,2YMXW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Cytochrome c biogenesis protein	ccsBA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
k59_915078_1	1537917.JU82_03130	1.74e-118	356.0	COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,42MPN@68525|delta/epsilon subdivisions,2YMHV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Flagellar basal body protein	-	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bb_rod,Flg_bbr_C
k59_731341_1	1395571.TMS3_0100540	2.21e-66	217.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RNE4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
k59_508930_1	709032.Sulku_0062	1.98e-139	394.0	COG0778@1|root,COG0778@2|Bacteria,1N95W@1224|Proteobacteria,42RYF@68525|delta/epsilon subdivisions,2YP3N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Nitroreductase	frxA	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_322150_1	1249480.B649_02550	1.05e-86	257.0	2AMMX@1|root,31CI0@2|Bacteria,1Q8WA@1224|Proteobacteria,42UGB@68525|delta/epsilon subdivisions,2YPW0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_322150_2	760154.Sulba_1705	9.32e-21	87.8	COG0115@1|root,COG0115@2|Bacteria,1N3ZD@1224|Proteobacteria,42TNN@68525|delta/epsilon subdivisions,2YPU5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EH	Branched-chain amino acid aminotransferase	-	-	4.1.3.38	ko:K02619	ko00790,map00790	-	R05553	RC01843,RC02148	ko00000,ko00001,ko01000	-	-	-	Aminotran_4
k59_445247_1	1537917.JU82_11095	2.69e-99	314.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2YN6Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DNA mismatch repair MutS family	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_III,MutS_V
k59_1323042_2	1123326.JFBL01000006_gene931	3.39e-57	188.0	COG0492@1|root,COG0492@2|Bacteria,1NDW6@1224|Proteobacteria,42MUD@68525|delta/epsilon subdivisions,2YMV2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	pyridine nucleotide-disulfide oxidoreductase	trxB_2	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	FixS,Pyr_redox_3
k59_324357_1	1537917.JU82_10905	1.54e-104	322.0	COG1034@1|root,COG1034@2|Bacteria,1RCFT@1224|Proteobacteria,42NK4@68525|delta/epsilon subdivisions,2YNI6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G)	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4_10,Molybdopterin,NADH-G_4Fe-4S_3
k59_1864252_1	1123242.JH636435_gene1329	0.00058	48.9	COG1538@1|root,COG1538@2|Bacteria,2IZ1P@203682|Planctomycetes	203682|Planctomycetes	MU	Outer membrane efflux protein	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
k59_1158601_1	1249480.B649_00865	4.38e-53	172.0	COG0035@1|root,COG0035@2|Bacteria,1MV4N@1224|Proteobacteria,42NNR@68525|delta/epsilon subdivisions,2YMH0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
k59_1158601_2	1249480.B649_00860	2.86e-39	130.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,42TRU@68525|delta/epsilon subdivisions,2YPS3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
k59_386290_1	1537917.JU82_06995	3.27e-124	362.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,42NCH@68525|delta/epsilon subdivisions,2YMW7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_1740409_1	1121035.AUCH01000007_gene560	1e-194	543.0	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,2VIQ5@28216|Betaproteobacteria,2KUKK@206389|Rhodocyclales	206389|Rhodocyclales	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
k59_158970_1	580332.Slit_1816	1.04e-57	203.0	COG2132@1|root,COG2132@2|Bacteria,1PM6Q@1224|Proteobacteria,2VKR2@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	TIG
k59_324382_1	1537917.JU82_02925	5.71e-82	253.0	2AIMJ@1|root,3193W@2|Bacteria,1Q1QU@1224|Proteobacteria,42U73@68525|delta/epsilon subdivisions,2YSXF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1740425_1	709032.Sulku_1566	2.31e-118	347.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,42MIA@68525|delta/epsilon subdivisions,2YMH1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_1740425_2	709032.Sulku_1567	1.46e-53	172.0	COG0586@1|root,COG0586@2|Bacteria,1R5SJ@1224|Proteobacteria,43AE6@68525|delta/epsilon subdivisions,2YT12@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
k59_1278255_1	717773.Thicy_0241	6.54e-106	338.0	COG0247@1|root,COG0277@1|root,COG0479@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,COG0479@2|Bacteria,1MU43@1224|Proteobacteria,1RMRH@1236|Gammaproteobacteria,45ZTB@72273|Thiotrichales	72273|Thiotrichales	C	Domain of unknown function (DUF3400)	-	-	-	-	-	-	-	-	-	-	-	-	CCG,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_8
k59_1740436_1	1537917.JU82_09155	4.58e-26	97.4	2AK6X@1|root,31AX3@2|Bacteria,1Q6DV@1224|Proteobacteria,432YY@68525|delta/epsilon subdivisions,2YSIQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Anti-sigma-28 factor, FlgM	-	-	-	-	-	-	-	-	-	-	-	-	FlgM
k59_1740436_2	1249480.B649_03460	2.92e-57	180.0	2AIM0@1|root,32I9V@2|Bacteria,1Q1S6@1224|Proteobacteria,42U9Z@68525|delta/epsilon subdivisions,2YPXP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_214846_1	159087.Daro_3703	1.1e-144	416.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,2VI9I@28216|Betaproteobacteria,2KU6U@206389|Rhodocyclales	206389|Rhodocyclales	P	Ammonium Transporter Family	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
k59_1388606_1	1123487.KB892846_gene675	4.13e-57	191.0	COG2710@1|root,COG2710@2|Bacteria,1MWQ4@1224|Proteobacteria,2VIUM@28216|Betaproteobacteria,2KVCW@206389|Rhodocyclales	206389|Rhodocyclales	C	This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation	-	-	1.18.6.1	ko:K02591	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF3364,Oxidored_nitro
k59_1388606_2	1121035.AUCH01000018_gene2759	9.92e-99	299.0	COG2710@1|root,COG2710@2|Bacteria,1MVY2@1224|Proteobacteria,2VHMG@28216|Betaproteobacteria,2KVM9@206389|Rhodocyclales	206389|Rhodocyclales	C	Nitrogenase component 1 type Oxidoreductase	-	-	1.18.6.1	ko:K02586	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_nitro
k59_447700_1	118797.XP_007451680.1	6.03e-21	93.2	COG0441@1|root,KOG1637@2759|Eukaryota,38C5Y@33154|Opisthokonta,3B9Y5@33208|Metazoa,3CVGA@33213|Bilateria,4843X@7711|Chordata	33208|Metazoa	J	threonine-tRNA ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	IF3_C,IF3_N,tRNA-synt_2b,tRNA_SAD
k59_447700_2	870187.Thini_0874	6.52e-90	283.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,1RMYE@1236|Gammaproteobacteria,45ZTX@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
k59_1388613_1	709032.Sulku_2496	1.05e-08	55.5	COG3439@1|root,COG3439@2|Bacteria,1RBWN@1224|Proteobacteria,43BBQ@68525|delta/epsilon subdivisions,2YT7G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_214857_1	1249480.B649_00595	3.64e-106	332.0	COG0715@1|root,COG0834@1|root,COG4191@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PNA@68525|delta/epsilon subdivisions,2YTBI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EPT	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,NMT1,SBP_bac_3
k59_1158658_1	709032.Sulku_0271	8.57e-166	485.0	COG1034@1|root,COG1034@2|Bacteria,1RCFT@1224|Proteobacteria,42NK4@68525|delta/epsilon subdivisions,2YNI6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G)	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4,Fer4_7,NADH-G_4Fe-4S_3
k59_386334_2	498211.CJA_0325	6.84e-34	120.0	COG2146@1|root,COG2146@2|Bacteria,1MZBY@1224|Proteobacteria,1S9F1@1236|Gammaproteobacteria,1FHCU@10|Cellvibrio	1236|Gammaproteobacteria	P	Rieske-like [2Fe-2S] domain	nirD	-	1.7.1.15	ko:K00363	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske_2
k59_386334_3	717773.Thicy_0782	7.52e-30	117.0	COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,1RNGY@1236|Gammaproteobacteria,45ZRS@72273|Thiotrichales	72273|Thiotrichales	C	TIGRFAM nitrite reductase NAD(P)H , large subunit	-	-	1.7.1.15	ko:K00362	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2
k59_511376_2	1249480.B649_02400	4.29e-82	248.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,42P56@68525|delta/epsilon subdivisions,2YNV5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
k59_1325903_1	709032.Sulku_1993	1.6e-41	141.0	COG0748@1|root,COG0748@2|Bacteria,1REH2@1224|Proteobacteria,42WSK@68525|delta/epsilon subdivisions,2YQ8W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07226	-	-	-	-	ko00000	-	-	-	DUF2470,Putative_PNPOx
k59_33751_1	1249480.B649_05905	8.45e-32	114.0	COG0319@1|root,COG0319@2|Bacteria,1Q9G0@1224|Proteobacteria,42SJD@68525|delta/epsilon subdivisions,2YPJA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
k59_33751_2	709032.Sulku_1424	6e-99	303.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,42M1S@68525|delta/epsilon subdivisions,2YMEF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	penicillin-binding protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
k59_91107_2	1537917.JU82_04330	2.34e-34	119.0	COG3630@1|root,COG3630@2|Bacteria	2|Bacteria	C	sodium ion export across plasma membrane	oadG	GO:0003674,GO:0003824,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008948,GO:0015672,GO:0016829,GO:0016830,GO:0016831,GO:0030001,GO:0051179,GO:0051234	4.1.1.3	ko:K01573	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_gamma
k59_982002_2	1249480.B649_09235	7.87e-75	229.0	COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,42SQE@68525|delta/epsilon subdivisions,2YPHI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	GO:0003674,GO:0003824,GO:0004141,GO:0016874,GO:0016879,GO:0016882	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
k59_1278329_1	395494.Galf_2568	4.4e-99	318.0	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG2202@1|root,COG3290@1|root,COG3829@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3290@2|Bacteria,COG3829@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria,44W7C@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Histidine Phosphotransfer domain	-	-	2.7.13.1	ko:K05962	-	-	-	-	ko00000,ko01000	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg
k59_1622520_1	326298.Suden_1055	7.14e-48	157.0	COG1014@1|root,COG1014@2|Bacteria,1R8XG@1224|Proteobacteria,42NPD@68525|delta/epsilon subdivisions,2YMM0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	oxidoreductase	oorC	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
k59_1622520_2	387093.SUN_0580	1.47e-46	157.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,42MD3@68525|delta/epsilon subdivisions,2YMMW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Oxidoreductase	oorB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
k59_324457_1	1150621.SMUL_0080	5.63e-64	221.0	COG0715@1|root,COG0834@1|root,COG2199@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG2199@2|Bacteria,1RGCV@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	yeaI	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0032879,GO:0040012,GO:0040013,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051270,GO:0051271,GO:0065007,GO:0071944,GO:1902021,GO:1902201,GO:2000145,GO:2000146	2.7.7.65	ko:K20959	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_853	CHASE,EAL,GGDEF,MASE4,NMT1,PAS,PAS_3
k59_1680971_1	709032.Sulku_1547	1.27e-116	343.0	COG3864@1|root,COG3864@2|Bacteria,1Q995@1224|Proteobacteria,42YHV@68525|delta/epsilon subdivisions,2YRK9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Putative metallopeptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
k59_1045632_1	1304883.KI912532_gene221	7.31e-134	387.0	COG1686@1|root,COG1686@2|Bacteria,1MWZA@1224|Proteobacteria,2VH1S@28216|Betaproteobacteria,2KUX8@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the peptidase S11 family	pbp	-	-	ko:K07262	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
k59_1504532_1	416591.Tlet_0327	9.16e-11	68.9	COG0204@1|root,COG0204@2|Bacteria,2GCWB@200918|Thermotogae	200918|Thermotogae	I	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k59_91142_1	314285.KT71_05972	3.29e-05	48.5	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,1S0QX@1236|Gammaproteobacteria,1JB61@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	helix_turn_helix, Lux Regulon	nreC	-	-	ko:K14979	ko02020,map02020	M00663	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
k59_91142_2	709032.Sulku_0471	3.91e-31	114.0	COG1776@1|root,COG1776@2|Bacteria,1N49I@1224|Proteobacteria,42UKN@68525|delta/epsilon subdivisions,2YQBN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	COGs COG1776 Chemotaxis protein CheC inhibitor of MCP methylation	-	-	-	ko:K03410	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheC,CheX
k59_1797193_2	470.IX87_06680	2.88e-11	71.2	COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,1RMZT@1236|Gammaproteobacteria,3NJUN@468|Moraxellaceae	1236|Gammaproteobacteria	T	Domain of unknown function (DUF4118)	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA,KdpD,Usp
k59_1388709_1	998674.ATTE01000001_gene477	2.53e-72	233.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,1RN88@1236|Gammaproteobacteria,45ZR5@72273|Thiotrichales	72273|Thiotrichales	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_1325983_1	709032.Sulku_0492	1.42e-113	332.0	COG1579@1|root,COG1579@2|Bacteria,1R7GT@1224|Proteobacteria,42P3S@68525|delta/epsilon subdivisions,2YMAN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COG1579 Zn-ribbon protein possibly nucleic acid-binding	-	-	3.5.4.16	ko:K07164,ko:K22391	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	zf-RING_7
k59_1325983_2	1249480.B649_02460	3.92e-83	250.0	COG0327@1|root,COG0327@2|Bacteria,1MVUN@1224|Proteobacteria,42MHJ@68525|delta/epsilon subdivisions,2YMM1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	dinuclear metal center protein, YbgI	-	-	3.5.4.16	ko:K22391	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	NIF3
k59_628885_1	1249480.B649_00010	1.02e-213	594.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,42NQW@68525|delta/epsilon subdivisions,2YM9J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
k59_628885_2	709032.Sulku_0003	0.0	929.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,42M7M@68525|delta/epsilon subdivisions,2YMUW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_33827_1	438753.AZC_4442	1.05e-72	233.0	COG0174@1|root,COG0174@2|Bacteria,1MU6V@1224|Proteobacteria,2TRCP@28211|Alphaproteobacteria,3EYIZ@335928|Xanthobacteraceae	28211|Alphaproteobacteria	E	Glutamine synthetase, catalytic domain	glnA1	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
k59_1453466_1	159087.Daro_1748	2.79e-138	400.0	COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,2VHJY@28216|Betaproteobacteria,2KVYE@206389|Rhodocyclales	206389|Rhodocyclales	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
k59_733947_1	583345.Mmol_2133	4.8e-181	529.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2VIJE@28216|Betaproteobacteria,2KKD7@206350|Nitrosomonadales	206350|Nitrosomonadales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	-
k59_982068_1	709032.Sulku_2222	3.45e-64	213.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,43BJ8@68525|delta/epsilon subdivisions,2YMMJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	penicillin-binding protein	pbpA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
k59_982068_2	1249480.B649_10480	2.53e-47	155.0	COG0586@1|root,COG0586@2|Bacteria,1R5SJ@1224|Proteobacteria,42RIW@68525|delta/epsilon subdivisions,2YP6Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	membrane-associated protein	dedA	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
k59_1095641_1	1537917.JU82_03595	1.1e-08	55.5	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,42MPZ@68525|delta/epsilon subdivisions,2YM8C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k59_1095641_2	1249480.B649_08780	3.5e-62	193.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
k59_1095641_3	709032.Sulku_0709	3.38e-107	311.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,42T4I@68525|delta/epsilon subdivisions,2YPMM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the UPF0312 family	Cj0420	-	-	-	-	-	-	-	-	-	-	-	YceI
k59_214981_1	318161.Sden_1294	4.6e-22	97.4	294XI@1|root,2ZSAH@2|Bacteria,1RDZH@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_2
k59_214988_1	290315.Clim_2274	9.52e-12	67.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	-	-	-	ko:K12543	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	1.B.17,3.A.1.109.4	-	-	OEP
k59_1504587_1	1537917.JU82_06990	1.57e-99	298.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,42MGN@68525|delta/epsilon subdivisions,2YNAN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Chorismate mutase prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
k59_1326054_1	709032.Sulku_0870	4.93e-109	329.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,42ME5@68525|delta/epsilon subdivisions,2YMKK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
k59_691513_1	317025.Tcr_1170	5.83e-111	331.0	COG0446@1|root,COG0446@2|Bacteria,1QUQF@1224|Proteobacteria,1RP1H@1236|Gammaproteobacteria,46027@72273|Thiotrichales	72273|Thiotrichales	S	PFAM Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_324543_1	1123393.KB891316_gene1303	1.46e-34	122.0	2BM92@1|root,32FST@2|Bacteria,1PWP8@1224|Proteobacteria,2WC7N@28216|Betaproteobacteria,1KT7A@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_324543_2	1123393.KB891316_gene1302	1.44e-72	219.0	COG1714@1|root,COG1714@2|Bacteria,1N7R6@1224|Proteobacteria,2WFRR@28216|Betaproteobacteria,1KTIE@119069|Hydrogenophilales	119069|Hydrogenophilales	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
k59_1453541_1	387093.SUN_0346	2.3e-229	655.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,42M70@68525|delta/epsilon subdivisions,2YMJM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_1045731_3	1249480.B649_03070	2.98e-05	43.1	COG0776@1|root,COG0776@2|Bacteria,1QQYR@1224|Proteobacteria,42V36@68525|delta/epsilon subdivisions,2YQA9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the bacterial histone-like protein family	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k59_447900_1	709032.Sulku_1365	2.25e-133	386.0	COG0665@1|root,COG0665@2|Bacteria,1Q0BQ@1224|Proteobacteria,42RXA@68525|delta/epsilon subdivisions,2YP66@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	COGs COG0665 Glycine D-amino acid oxidase (deaminating)	-	-	2.1.1.61	ko:K15461	-	-	R00601,R08702	RC00003,RC00053,RC00060,RC01483	ko00000,ko01000,ko03016	-	-	-	DAO
k59_1095726_1	1537917.JU82_04690	4.15e-102	301.0	COG2204@1|root,COG2204@2|Bacteria,1QASN@1224|Proteobacteria,42RV2@68525|delta/epsilon subdivisions,2YP76@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activ_2,Sigma54_activat
k59_511585_2	1202532.FF52_06560	9.99e-19	82.4	COG3829@1|root,COG3829@2|Bacteria,4NMZD@976|Bacteroidetes,1I2PY@117743|Flavobacteriia,2NTGP@237|Flavobacterium	976|Bacteroidetes	KT	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	PAS_3
k59_1326136_1	387093.SUN_1967	1.78e-20	87.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,42P2Z@68525|delta/epsilon subdivisions,2YN11@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
k59_1326136_2	1165841.SULAR_06743	1.09e-83	258.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,42MSB@68525|delta/epsilon subdivisions,2YMBS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
k59_1388875_1	1121116.KB894767_gene2183	2.49e-15	76.6	COG0583@1|root,COG0583@2|Bacteria,1MVHT@1224|Proteobacteria,2VHF0@28216|Betaproteobacteria,4AAN1@80864|Comamonadaceae	28216|Betaproteobacteria	K	LysR substrate binding domain	-	-	-	ko:K03717	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k59_1095762_1	159087.Daro_0289	1.17e-18	78.2	COG2921@1|root,COG2921@2|Bacteria,1RGV5@1224|Proteobacteria,2VTY5@28216|Betaproteobacteria,2KWZM@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the UPF0250 family	-	-	-	ko:K09158	-	-	-	-	ko00000	-	-	-	DUF493
k59_1095762_2	159087.Daro_0288	7.16e-99	290.0	COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,2VQ1Y@28216|Betaproteobacteria,2KW5V@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
k59_386538_1	1249480.B649_08260	1.38e-51	168.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,42R5H@68525|delta/epsilon subdivisions,2YNYJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
k59_386538_2	1249480.B649_08265	3.6e-39	140.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2YMQG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
k59_734102_2	1249480.B649_08385	1.93e-25	102.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,42MNP@68525|delta/epsilon subdivisions,2YQ4S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
k59_1761384_2	1249480.B649_01025	3.47e-130	375.0	COG1684@1|root,COG1684@2|Bacteria,1NIF4@1224|Proteobacteria,42NX7@68525|delta/epsilon subdivisions,2YMKE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Flagellar biosynthetic protein fliR	fliR	-	-	ko:K02421	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1
k59_1761384_3	326298.Suden_1799	6.17e-11	61.6	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,42PQP@68525|delta/epsilon subdivisions,2YNQ7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	abc transporter atp-binding protein	ybbA	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_822132_1	305700.B447_05730	1.57e-108	319.0	28K85@1|root,2Z9W1@2|Bacteria,1MWB1@1224|Proteobacteria,2W4HH@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
k59_646113_1	159087.Daro_0012	1.68e-14	79.3	COG0745@1|root,COG0745@2|Bacteria,1R52E@1224|Proteobacteria,2VZQH@28216|Betaproteobacteria,2KWDF@206389|Rhodocyclales	206389|Rhodocyclales	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_1820163_1	709032.Sulku_0830	2.91e-19	85.1	COG0676@1|root,COG0676@2|Bacteria,1Q7VN@1224|Proteobacteria,42SFK@68525|delta/epsilon subdivisions,2YPP5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the glucose-6-phosphate 1-epimerase family	-	-	5.1.3.15	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	-	R02739	RC00563	ko00000,ko00001,ko01000	-	-	-	Aldose_epim
k59_1526646_1	709032.Sulku_2176	8.87e-102	316.0	COG4206@1|root,COG4206@2|Bacteria,1QUPS@1224|Proteobacteria,43CID@68525|delta/epsilon subdivisions,2YTCZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_822150_1	709032.Sulku_2224	6.45e-91	276.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,42MM1@68525|delta/epsilon subdivisions,2YN3A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	8-amino-7-oxononanoate synthase	bioF	-	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_1526656_1	1249480.B649_06600	1.1e-76	252.0	COG2199@1|root,COG2200@1|root,COG3287@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,COG3287@2|Bacteria,1NQKX@1224|Proteobacteria,43DAG@68525|delta/epsilon subdivisions,2YTHK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,FIST,FIST_C,GGDEF,PAS_9
k59_646147_1	159087.Daro_2966	5.37e-79	246.0	COG2199@1|root,COG2199@2|Bacteria,1QTQM@1224|Proteobacteria,2W1IR@28216|Betaproteobacteria	28216|Betaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_436_1	1045004.OKIT_1133	2.81e-13	66.6	COG0590@1|root,COG0590@2|Bacteria,1V7G0@1239|Firmicutes,4HMR9@91061|Bacilli	91061|Bacilli	FJ	MafB19-like deaminase	guaD	-	-	-	-	-	-	-	-	-	-	-	MafB19-deam,dCMP_cyt_deam_1
k59_436_2	1121374.KB891576_gene511	3.82e-14	75.1	28NHW@1|root,2ZBJG@2|Bacteria,1RBJB@1224|Proteobacteria,1S31B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_469974_1	1249480.B649_04830	1.53e-89	276.0	2AJS6@1|root,31AEF@2|Bacteria,1Q5FI@1224|Proteobacteria,4315Z@68525|delta/epsilon subdivisions,2YSA1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_117717_1	1134474.O59_002044	1.04e-25	102.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,1RN4H@1236|Gammaproteobacteria,1FH0D@10|Cellvibrio	1236|Gammaproteobacteria	L	Endonuclease/Exonuclease/phosphatase family	xthA	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008853,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
k59_117717_2	574966.KB898647_gene2680	5.36e-46	160.0	COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,1RNPS@1236|Gammaproteobacteria,1XJNB@135619|Oceanospirillales	135619|Oceanospirillales	M	(Lipo)protein	vacJ	-	-	ko:K04754	-	-	-	-	ko00000	-	-	-	MlaA
k59_352503_2	709032.Sulku_1936	8.52e-43	149.0	COG0147@1|root,COG0147@2|Bacteria,1R5Y8@1224|Proteobacteria,42P2B@68525|delta/epsilon subdivisions,2YMFR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EH	component I	pabB	-	2.6.1.85	ko:K01665	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	Chorismate_bind
k59_1761440_1	1249480.B649_08665	7.24e-11	58.2	2BJZK@1|root,32ECD@2|Bacteria,1QDIV@1224|Proteobacteria,433KD@68525|delta/epsilon subdivisions,2YSRX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1761440_2	1249480.B649_08655	1.3e-92	271.0	COG3829@1|root,COG3829@2|Bacteria,1RH32@1224|Proteobacteria,42QQM@68525|delta/epsilon subdivisions,2YNZA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	signal transduction sensor histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PAS,PAS_3
k59_1174414_1	1249480.B649_03115	1e-76	248.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42YH8@68525|delta/epsilon subdivisions,2YRAU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
k59_998306_1	159087.Daro_2004	3.23e-72	219.0	COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,2VSKW@28216|Betaproteobacteria,2KWGB@206389|Rhodocyclales	206389|Rhodocyclales	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	ptpA	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
k59_998306_2	1304883.KI912532_gene2460	8.2e-12	66.6	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,2VIE5@28216|Betaproteobacteria,2KV38@206389|Rhodocyclales	206389|Rhodocyclales	J	Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs	rne	-	3.1.26.12	ko:K08300	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
k59_646193_1	709032.Sulku_2293	7.12e-110	323.0	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,42MIX@68525|delta/epsilon subdivisions,2YM93@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
k59_1644027_2	1249480.B649_06190	2.34e-94	278.0	COG3043@1|root,COG3043@2|Bacteria,1NAZB@1224|Proteobacteria,42SN1@68525|delta/epsilon subdivisions,2YPF9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB	napB	-	-	ko:K02568	ko00910,ko01120,map00910,map01120	M00529,M00530	R00798	RC02812	ko00000,ko00001,ko00002	-	-	-	NapB
k59_880882_1	1165096.ARWF01000001_gene1581	2.36e-118	352.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,2VHQU@28216|Betaproteobacteria,2KKGG@206350|Nitrosomonadales	206350|Nitrosomonadales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_1820259_2	1537917.JU82_08315	7.35e-73	229.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,42M5V@68525|delta/epsilon subdivisions,2YM81@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Cysteine desulfurase	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
k59_352547_1	754477.Q7C_920	1.34e-66	208.0	28IYH@1|root,2Z8W7@2|Bacteria,1PDS3@1224|Proteobacteria,1S107@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (Hypoth_ymh)	-	-	-	-	-	-	-	-	-	-	-	-	Hypoth_Ymh
k59_704807_1	1537917.JU82_09320	5.69e-110	350.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2YMRQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_1702816_1	1249480.B649_06485	1.1e-62	197.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,42QXV@68525|delta/epsilon subdivisions,2YNXY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
k59_1409184_2	1537917.JU82_02880	2.84e-36	129.0	COG2836@1|root,COG2836@2|Bacteria,1QZ1V@1224|Proteobacteria,430HB@68525|delta/epsilon subdivisions,2YRZU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	DsbD_2
k59_1585428_1	553218.CAMRE0001_0665	8.44e-50	176.0	COG2861@1|root,COG2861@2|Bacteria,1N3JP@1224|Proteobacteria,42RJN@68525|delta/epsilon subdivisions,2YP6V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Divergent polysaccharide deacetylase	-	-	-	ko:K09798	-	-	-	-	ko00000	-	-	-	Polysacc_deac_2
k59_1585428_2	1537917.JU82_09915	4.08e-25	100.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,42N10@68525|delta/epsilon subdivisions,2YMIF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	LU	DNA processing protein	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
k59_528847_1	457570.Nther_2778	3.04e-103	312.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia	186801|Clostridia	L	Reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
k59_470102_1	640081.Dsui_0657	4.09e-21	97.1	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VJBX@28216|Betaproteobacteria,2KU9U@206389|Rhodocyclales	206389|Rhodocyclales	NT	Methyl-accepting chemotaxis protein	pilJ	-	-	ko:K02660	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	MCPsignal,PilJ
k59_587434_1	1537917.JU82_01410	4.76e-13	67.8	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MKR@68525|delta/epsilon subdivisions,2YN1A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Aminotransferase	aspB	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_587434_2	1537917.JU82_01430	3.43e-39	130.0	2AK1D@1|root,31AQZ@2|Bacteria,1Q5ZH@1224|Proteobacteria,42V6N@68525|delta/epsilon subdivisions,2YQ6B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_587434_3	1249480.B649_05320	2.61e-103	301.0	29668@1|root,2ZTGD@2|Bacteria,1Q60I@1224|Proteobacteria,4326Q@68525|delta/epsilon subdivisions,2YSIU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1350559_1	709032.Sulku_2307	1.75e-46	160.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,42MZZ@68525|delta/epsilon subdivisions,2YMM3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	molybdopterin biosynthesis	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
k59_1350559_2	1249480.B649_10890	1.31e-127	363.0	COG0720@1|root,COG0720@2|Bacteria,1R62M@1224|Proteobacteria,42R4Z@68525|delta/epsilon subdivisions,2YNZW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	synthase	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
k59_1350559_3	243275.TDE_1960	2.22e-08	52.0	COG4226@1|root,COG4226@2|Bacteria,2J8RI@203691|Spirochaetes	203691|Spirochaetes	S	protein encoded in hypervariable junctions of pilus gene clusters	-	-	-	-	-	-	-	-	-	-	-	-	HicB
k59_822293_1	582744.Msip34_0727	6.85e-88	281.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	type II secretion system protein E	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
k59_293901_1	709032.Sulku_1666	2.08e-101	300.0	COG0642@1|root,COG2205@2|Bacteria,1RK1D@1224|Proteobacteria,42R91@68525|delta/epsilon subdivisions,2YNX3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
k59_646317_1	1249480.B649_06965	9.36e-15	68.2	COG0633@1|root,COG0633@2|Bacteria,1NJF0@1224|Proteobacteria,42U1V@68525|delta/epsilon subdivisions,2YQ25@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Fer2
k59_646317_2	1537917.JU82_01570	1.69e-127	372.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,42M3C@68525|delta/epsilon subdivisions,2YNGF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
k59_1350574_1	90814.KL370891_gene884	2.06e-79	253.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,1RPFB@1236|Gammaproteobacteria,45ZWP@72273|Thiotrichales	72273|Thiotrichales	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
k59_176457_1	1249480.B649_04090	1.21e-201	572.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1R5RS@1224|Proteobacteria,42M3K@68525|delta/epsilon subdivisions,2YN6E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	PFAM biotin lipoyl attachment domain-containing protein	pycB	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
k59_646342_1	519989.ECTPHS_09532	1.06e-39	135.0	COG0537@1|root,COG0537@2|Bacteria,1MZVD@1224|Proteobacteria	1224|Proteobacteria	FG	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases	MA20_21960	-	-	-	-	-	-	-	-	-	-	-	HIT
k59_646342_2	159087.Daro_4121	5.43e-16	76.3	COG0247@1|root,COG0277@1|root,COG0479@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,COG0479@2|Bacteria,1MU43@1224|Proteobacteria,2VHYU@28216|Betaproteobacteria,2KUWB@206389|Rhodocyclales	206389|Rhodocyclales	C	FAD linked oxidase	-	-	-	-	-	-	-	-	-	-	-	-	CCG,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_8
k59_1526841_1	1249480.B649_11720	4.51e-90	267.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,42RFN@68525|delta/epsilon subdivisions,2YP6C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
k59_1526841_2	1537917.JU82_05125	5.08e-185	522.0	COG2199@1|root,COG3706@2|Bacteria,1QV14@1224|Proteobacteria,42NPJ@68525|delta/epsilon subdivisions,2YNH9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_1526841_3	709032.Sulku_2526	3.07e-133	378.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,42MFU@68525|delta/epsilon subdivisions,2YMBZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
k59_1526841_4	709032.Sulku_2525	3.28e-92	281.0	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,42MBB@68525|delta/epsilon subdivisions,2YMFZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
k59_1057040_1	395494.Galf_1402	1.62e-92	285.0	COG0664@1|root,COG0668@1|root,COG0664@2|Bacteria,COG0668@2|Bacteria,1R6J6@1224|Proteobacteria,2VPCU@28216|Betaproteobacteria,44W84@713636|Nitrosomonadales	28216|Betaproteobacteria	MT	MscS Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,cNMP_binding
k59_411377_1	1537917.JU82_08095	2.15e-116	350.0	COG0702@1|root,COG0702@2|Bacteria,1PDTN@1224|Proteobacteria,42M8X@68525|delta/epsilon subdivisions,2YM7Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
k59_648_1	1249480.B649_07405	3.36e-141	419.0	COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,42MP9@68525|delta/epsilon subdivisions,2YMN8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Type I secretion system ATPase	-	-	-	ko:K12541	ko02010,map02010	M00330	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.109.3,3.A.1.109.4	-	-	ABC_membrane,ABC_tran
k59_763523_1	243365.CV_3687	2.47e-40	139.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,2VJ9D@28216|Betaproteobacteria,2KPNG@206351|Neisseriales	28216|Betaproteobacteria	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
k59_704893_1	159087.Daro_0616	1.2e-64	199.0	COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,2VR5W@28216|Betaproteobacteria,2KWB7@206389|Rhodocyclales	206389|Rhodocyclales	J	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
k59_704893_2	340099.Teth39_1788	5.04e-23	96.7	COG1040@1|root,COG1040@2|Bacteria,1VF2G@1239|Firmicutes,24IG6@186801|Clostridia,42FNR@68295|Thermoanaerobacterales	186801|Clostridia	F	PFAM Phosphoribosyltransferase	comF	-	-	ko:K02242	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	Pribosyltran
k59_1233276_1	1249480.B649_02335	0.000109	42.0	COG2963@1|root,COG2963@2|Bacteria,1MZ5C@1224|Proteobacteria	1224|Proteobacteria	L	COG2963, Transposase and inactivated derivatives	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
k59_1820401_1	1349767.GJA_70	4.19e-15	75.5	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,2VJ7K@28216|Betaproteobacteria,472S3@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
k59_1820401_2	1304883.KI912532_gene1660	5.31e-137	390.0	COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,2VIF9@28216|Betaproteobacteria,2KUBS@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
k59_1526869_1	1537917.JU82_02265	9.58e-93	279.0	COG0679@1|root,COG0679@2|Bacteria,1PHSS@1224|Proteobacteria,42M30@68525|delta/epsilon subdivisions,2YN5E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	auxin efflux carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
k59_1761594_1	382245.ASA_0283	1.52e-131	410.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,1RMK0@1236|Gammaproteobacteria,1Y3R5@135624|Aeromonadales	135624|Aeromonadales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_352643_1	1537917.JU82_08615	2.13e-54	179.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,42N1I@68525|delta/epsilon subdivisions,2YMA0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome	ccpA	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
k59_1585506_1	709032.Sulku_1466	1.55e-59	208.0	COG2982@1|root,COG2982@2|Bacteria,1QA6E@1224|Proteobacteria,42NCN@68525|delta/epsilon subdivisions,2YM89@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_1,DUF3971
k59_235300_1	857087.Metme_3254	3.19e-60	213.0	COG2202@1|root,COG3221@1|root,COG5001@1|root,COG2202@2|Bacteria,COG3221@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,CZB,EAL,GAF_2,GGDEF,PAS_3,PAS_4,PAS_9,Protoglobin
k59_998466_1	1537917.JU82_09120	6.76e-96	306.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,42MGK@68525|delta/epsilon subdivisions,2YMHU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_646402_1	709032.Sulku_1828	2.43e-119	358.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MHP@68525|delta/epsilon subdivisions,2YN92@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k59_1409259_1	1249480.B649_02595	2.77e-19	82.4	2BTJ1@1|root,32NRK@2|Bacteria,1Q3XC@1224|Proteobacteria,42RS4@68525|delta/epsilon subdivisions,2YPVI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Lipopolysaccharide-assembly	-	-	-	-	-	-	-	-	-	-	-	-	LptE
k59_1409259_2	709032.Sulku_0518	4.81e-135	405.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,42MRQ@68525|delta/epsilon subdivisions,2YMJY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1g
k59_1585525_1	1304883.KI912532_gene404	1.63e-182	522.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VI6G@28216|Betaproteobacteria,2KUBK@206389|Rhodocyclales	206389|Rhodocyclales	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	lpd	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
k59_646441_1	1537917.JU82_06955	3.18e-22	94.0	COG0176@1|root,COG0176@2|Bacteria,1N9G3@1224|Proteobacteria,42MCK@68525|delta/epsilon subdivisions,2YMRY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
k59_646441_2	1537917.JU82_06960	3.29e-187	527.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2YMC1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_1350664_1	232348.ADXL01000079_gene971	6.2e-43	158.0	COG0370@1|root,COG0370@2|Bacteria,1G058@1117|Cyanobacteria,1GYZT@1129|Synechococcus	1117|Cyanobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
k59_352687_1	563040.Saut_1076	5.09e-82	260.0	COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,42N0P@68525|delta/epsilon subdivisions,2YN14@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	UPF0313 protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,Radical_SAM_N
k59_352687_2	1165841.SULAR_03098	6.68e-63	212.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2YMMU@29547|Epsilonproteobacteria	68525|delta/epsilon subdivisions	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH-1	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_1704967_2	713586.KB900536_gene2509	5.7e-153	449.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1WWMQ@135613|Chromatiales	135613|Chromatiales	C	PFAM Aldehyde dehydrogenase	-	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_531425_1	90814.KL370891_gene857	4.68e-124	384.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,45ZPA@72273|Thiotrichales	72273|Thiotrichales	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_119994_1	159087.Daro_3478	4.51e-81	257.0	COG1807@1|root,COG1807@2|Bacteria,1P6JE@1224|Proteobacteria,2VN72@28216|Betaproteobacteria,2KU7A@206389|Rhodocyclales	206389|Rhodocyclales	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	PMT_2
k59_3409_1	159087.Daro_4148	9.04e-27	99.8	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,2VU5H@28216|Betaproteobacteria,2KWTT@206389|Rhodocyclales	206389|Rhodocyclales	J	sigma 54 modulation protein	-	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
k59_3409_2	159087.Daro_4147	1.68e-82	246.0	COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,2VRDH@28216|Betaproteobacteria,2KW4R@206389|Rhodocyclales	206389|Rhodocyclales	G	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)	ptsN	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
k59_1763713_2	1249480.B649_07235	7.33e-115	330.0	COG0503@1|root,COG0503@2|Bacteria,1MVZ6@1224|Proteobacteria,42QSH@68525|delta/epsilon subdivisions,2YNVB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
k59_1763713_3	1249480.B649_07230	1.28e-60	187.0	2AV85@1|root,31KYU@2|Bacteria,1QITS@1224|Proteobacteria,42SB2@68525|delta/epsilon subdivisions,2YQ0M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_237416_1	765911.Thivi_1361	1.17e-59	198.0	COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,1RNGJ@1236|Gammaproteobacteria,1WXQX@135613|Chromatiales	135613|Chromatiales	L	DNA photolyase	-	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
k59_1117852_1	326298.Suden_0046	8.76e-31	118.0	COG3137@1|root,COG3137@2|Bacteria,1PWI2@1224|Proteobacteria,42W3Z@68525|delta/epsilon subdivisions,2YQX2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Protein of unknown function, DUF481	-	-	-	ko:K07283	-	-	-	-	ko00000	-	-	-	DUF481
k59_1117852_2	1249480.B649_00235	7.89e-154	442.0	COG0477@1|root,COG2814@2|Bacteria,1MVZI@1224|Proteobacteria,42P57@68525|delta/epsilon subdivisions,2YMGG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EGP	Major facilitator superfamily	-	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1_like
k59_26492_2	709032.Sulku_2233	2.66e-85	258.0	COG2165@1|root,COG2165@2|Bacteria,1Q5XA@1224|Proteobacteria,42TXT@68525|delta/epsilon subdivisions,2YPZV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
k59_26492_3	1249480.B649_10560	7.53e-74	248.0	COG1195@1|root,COG1361@1|root,COG3055@1|root,COG1195@2|Bacteria,COG1361@2|Bacteria,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	Calx-beta,Kelch_1,Laminin_G_3
k59_681534_1	1249480.B649_02930	1.84e-81	255.0	COG2861@1|root,COG2861@2|Bacteria,1N3JP@1224|Proteobacteria,42RJN@68525|delta/epsilon subdivisions,2YP6V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Divergent polysaccharide deacetylase	-	-	-	ko:K09798	-	-	-	-	ko00000	-	-	-	Polysacc_deac_2
k59_681542_1	472759.Nhal_1054	1.03e-05	48.5	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,1RMFJ@1236|Gammaproteobacteria,1WWF7@135613|Chromatiales	135613|Chromatiales	H	TonB-dependent Receptor Plug	-	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
k59_681542_2	159087.Daro_4031	1.15e-60	195.0	COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,2VK1S@28216|Betaproteobacteria,2KVFR@206389|Rhodocyclales	206389|Rhodocyclales	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
k59_1149469_2	159087.Daro_0202	4.09e-44	155.0	COG1366@1|root,COG1366@2|Bacteria,1R08G@1224|Proteobacteria,2VIGK@28216|Betaproteobacteria,2KVYW@206389|Rhodocyclales	206389|Rhodocyclales	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	-	-	-	-	-	-	-	-	-	STAS_2
k59_1149471_2	1165841.SULAR_07565	1.64e-56	176.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,42VAT@68525|delta/epsilon subdivisions,2YPSQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iIT341.HP1270	Oxidored_q2
k59_1149471_3	749222.Nitsa_0169	5.97e-09	57.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2YN0B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
k59_1561743_2	1537917.JU82_09830	2.48e-44	146.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,42N4Z@68525|delta/epsilon subdivisions,2YTJ1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07305,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
k59_1149475_1	1165841.SULAR_05713	1.17e-92	285.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,42MVX@68525|delta/epsilon subdivisions,2YMSF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	iIT341.HP1134	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_1149475_2	387093.SUN_1774	3.68e-22	90.5	COG0712@1|root,COG0712@2|Bacteria,1RFPY@1224|Proteobacteria,42SKR@68525|delta/epsilon subdivisions,2YPHX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
k59_1268692_1	709032.Sulku_0493	1.79e-78	246.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,42PCH@68525|delta/epsilon subdivisions,2YN62@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	3-deoxy-d-manno-octulosonic-acid transferase	kdtA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	iIT341.HP0957	Glycos_transf_N
k59_1379439_1	1072685.IX83_07155	5.7e-18	76.6	2EJST@1|root,33DHF@2|Bacteria	2|Bacteria	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_39
k59_1731491_1	1249480.B649_10725	2.8e-107	310.0	COG0250@1|root,COG0250@2|Bacteria,1MU14@1224|Proteobacteria,42MPQ@68525|delta/epsilon subdivisions,2YMJK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
k59_1731491_2	1537917.JU82_01700	2.35e-25	95.1	COG0690@1|root,COG0690@2|Bacteria,1N8YN@1224|Proteobacteria,42VP0@68525|delta/epsilon subdivisions,2YQ7E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
k59_794180_1	211165.AJLN01000066_gene4524	6.27e-05	50.4	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,1FZWQ@1117|Cyanobacteria,1JHGB@1189|Stigonemataceae	1117|Cyanobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
k59_1561807_1	1249480.B649_05585	2.31e-25	100.0	COG0666@1|root,COG0666@2|Bacteria,1Q2UY@1224|Proteobacteria,42WAJ@68525|delta/epsilon subdivisions,2YQKP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_4,Ank_5
k59_378463_1	886379.AEWI01000022_gene188	1.02e-51	175.0	COG3385@1|root,COG3385@2|Bacteria,4PAZ3@976|Bacteroidetes,2G1BX@200643|Bacteroidia,3XKVM@558415|Marinilabiliaceae	976|Bacteroidetes	L	Domain of unknown function (DUF4372)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
k59_378463_2	598467.BrE312_2777	1.23e-11	63.9	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,1RPJM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	ATP-binding protein, IstB SW ISTB_ECOLI (P15026) (265 aa) fasta scores E() 0, 47.4 id in 249 aa. Also almost identical to Yersinia pestis and Escherichia coli	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
k59_619897_1	1537917.JU82_10790	4.84e-162	466.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,42MTY@68525|delta/epsilon subdivisions,2YMHI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
k59_317515_1	387093.SUN_1120	8.33e-105	308.0	COG3786@1|root,COG3786@2|Bacteria,1RH22@1224|Proteobacteria,42U32@68525|delta/epsilon subdivisions,2YPTI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COGs COG3786 conserved	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
k59_972419_1	709032.Sulku_0427	1.41e-100	298.0	COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,42PJB@68525|delta/epsilon subdivisions,2YNGQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k59_1561833_1	640081.Dsui_1556	1.55e-67	218.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,2VKCK@28216|Betaproteobacteria,2KVQF@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
k59_1317196_1	563040.Saut_1404	5.05e-131	381.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,42M0T@68525|delta/epsilon subdivisions,2YMEX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0183	SHMT
k59_1731543_1	709032.Sulku_0394	8.98e-24	100.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YMHP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3
k59_1731543_2	1537917.JU82_05230	6.42e-18	83.6	COG1042@1|root,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,42KZW@68525|delta/epsilon subdivisions,2YN6G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
k59_1855359_1	1267005.KB911263_gene1340	3.97e-19	92.8	COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MWDY@1224|Proteobacteria,2TTGI@28211|Alphaproteobacteria,3N9E8@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	I	Phosphate acyltransferases	aas	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
k59_1087245_2	338969.Rfer_3146	5.51e-23	92.4	COG3837@1|root,COG3837@2|Bacteria,1R9WZ@1224|Proteobacteria,2VRW2@28216|Betaproteobacteria,4AHWF@80864|Comamonadaceae	28216|Betaproteobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
k59_502809_1	1132855.KB913035_gene340	4.1e-193	548.0	COG2509@1|root,COG2509@2|Bacteria,1MV6P@1224|Proteobacteria,2VHGJ@28216|Betaproteobacteria,2KKNH@206350|Nitrosomonadales	206350|Nitrosomonadales	S	fad dependent oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	Pyr_redox_2
k59_972461_1	395494.Galf_1304	2.09e-68	218.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,2VMB2@28216|Betaproteobacteria,44W3T@713636|Nitrosomonadales	28216|Betaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_619946_2	273121.WS1878	2.05e-92	278.0	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,42MRS@68525|delta/epsilon subdivisions,2YNCB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0330	IlvC,IlvN
k59_1149580_1	159087.Daro_3308	4.81e-114	353.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VK78@28216|Betaproteobacteria,2KVI5@206389|Rhodocyclales	206389|Rhodocyclales	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k59_1149580_2	383372.Rcas_1114	2.03e-09	61.6	COG2204@1|root,COG2208@1|root,COG2204@2|Bacteria,COG2208@2|Bacteria,2GANJ@200795|Chloroflexi,376V4@32061|Chloroflexia	32061|Chloroflexia	T	SMART protein phosphatase 2C domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Hpt,Response_reg,SpoIIE
k59_1561883_1	159087.Daro_0312	1.78e-96	311.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,2VHF3@28216|Betaproteobacteria,2KV0Q@206389|Rhodocyclales	206389|Rhodocyclales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_439499_1	395494.Galf_0636	8.12e-36	143.0	COG2114@1|root,COG2982@1|root,COG3064@1|root,COG2114@2|Bacteria,COG2982@2|Bacteria,COG3064@2|Bacteria,1QZY2@1224|Proteobacteria,2VTEI@28216|Betaproteobacteria,44WBC@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1444430_1	159087.Daro_3403	5.48e-139	405.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VNYV@28216|Betaproteobacteria,2KV5E@206389|Rhodocyclales	206389|Rhodocyclales	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_726570_1	1537917.JU82_05855	1.94e-46	158.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,42QFD@68525|delta/epsilon subdivisions,2YND7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	FP	Ppx GppA	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
k59_1673047_1	1249480.B649_07670	2.03e-90	281.0	COG0539@1|root,COG2183@1|root,COG0539@2|Bacteria,COG2183@2|Bacteria,1MVAV@1224|Proteobacteria,42M29@68525|delta/epsilon subdivisions,2YMBM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	ribosomal protein S1	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
k59_1036047_1	1537917.JU82_01080	3.4e-70	222.0	COG2171@1|root,COG2171@2|Bacteria,1MYKK@1224|Proteobacteria,42MHI@68525|delta/epsilon subdivisions,2YMU8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep_2,THDPS_M,THDPS_N
k59_149987_1	709032.Sulku_1239	1.62e-91	290.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YNS1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4
k59_149994_1	90813.JQMT01000001_gene19	6.4e-53	179.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,1RS25@1236|Gammaproteobacteria,460MD@72273|Thiotrichales	72273|Thiotrichales	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
k59_1036090_2	1249480.B649_08730	5.21e-44	148.0	2BSDA@1|root,32MF9@2|Bacteria,1Q395@1224|Proteobacteria,42WZ0@68525|delta/epsilon subdivisions,2YQT3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1855514_1	387093.SUN_1196	8.39e-89	277.0	COG0665@1|root,COG0665@2|Bacteria,1QV9J@1224|Proteobacteria,42PP0@68525|delta/epsilon subdivisions,2YNBW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
k59_1149691_1	1168067.JAGP01000001_gene1386	1.7e-93	294.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,1RNKN@1236|Gammaproteobacteria,45ZMF@72273|Thiotrichales	72273|Thiotrichales	CP	Proton-translocating NADH-quinone oxidoreductase, chain L	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
k59_1268965_1	1049564.TevJSym_aa00430	1.79e-38	152.0	COG4191@1|root,COG5001@1|root,COG4191@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1T5JB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1087384_1	795666.MW7_1653	4.03e-19	87.8	COG4267@1|root,COG4267@2|Bacteria,1MUQN@1224|Proteobacteria,2VMET@28216|Betaproteobacteria,1K3XA@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Putative exopolysaccharide Exporter (EPS-E)	ragG	-	-	ko:K21012	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	PelG
k59_1087384_2	521719.ATXQ01000003_gene2029	2.68e-07	52.4	COG3909@1|root,COG3909@2|Bacteria,1N1E5@1224|Proteobacteria,1S4BY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_2
k59_206130_1	159087.Daro_2827	8.65e-154	452.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,2VHSK@28216|Betaproteobacteria,2KV96@206389|Rhodocyclales	206389|Rhodocyclales	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
k59_1202700_1	666681.M301_1907	1.62e-59	202.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,2VN53@28216|Betaproteobacteria,2KM14@206350|Nitrosomonadales	206350|Nitrosomonadales	I	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
k59_565057_2	1537917.JU82_03280	1.29e-40	135.0	COG1918@1|root,COG1918@2|Bacteria,1Q53C@1224|Proteobacteria,42X0A@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	Fe2 transport system protein A	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
k59_439625_3	314270.RB2083_1244	1.79e-06	52.4	COG4148@1|root,COG4148@2|Bacteria,1MU8K@1224|Proteobacteria,2TR1Z@28211|Alphaproteobacteria,3ZGKE@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	P	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system	modC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE
k59_1789829_1	1249480.B649_00960	4.57e-126	361.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,1MW67@1224|Proteobacteria,42SGH@68525|delta/epsilon subdivisions,2YNQD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Histidine biosynthesis bifunctional protein hisIE	hisI	-	3.5.4.19,3.6.1.31	ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH,PRA-PH
k59_1789829_2	709032.Sulku_0227	1.83e-06	48.1	2AK36@1|root,31ASY@2|Bacteria,1Q62K@1224|Proteobacteria,42W11@68525|delta/epsilon subdivisions,2YQDG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF2393)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2393
k59_681883_1	159087.Daro_3883	3.64e-148	422.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,2VHHW@28216|Betaproteobacteria,2KVBG@206389|Rhodocyclales	206389|Rhodocyclales	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_681883_2	159087.Daro_3884	4.58e-20	85.9	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,2VHNY@28216|Betaproteobacteria,2KU9T@206389|Rhodocyclales	206389|Rhodocyclales	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
k59_1855570_2	326442.PSHAa2320	1.06e-15	77.8	COG0438@1|root,COG0438@2|Bacteria,1QFQQ@1224|Proteobacteria,1RPY4@1236|Gammaproteobacteria,2Q1KE@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	Glycosyltransferase Family 4	rfaB	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_263893_1	1123518.ARWI01000001_gene1701	2.85e-60	211.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,45ZS0@72273|Thiotrichales	72273|Thiotrichales	T	Diguanylate cyclase phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_9
k59_1789837_1	1121440.AUMA01000006_gene1417	3.72e-24	104.0	COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,42N1F@68525|delta/epsilon subdivisions,2WK2V@28221|Deltaproteobacteria,2M8SJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	PFAM Phosphomethylpyrimidine kinase type-1	thiD	-	2.5.1.3,2.7.1.49,2.7.4.7	ko:K00941,ko:K14153,ko:K21219	ko00730,ko01100,map00730,map01100	M00127	R03223,R03471,R04509,R10712	RC00002,RC00017,RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2909	Phos_pyr_kin,TMP-TENI,ThiP_synth
k59_86363_2	1249480.B649_04300	1.34e-77	233.0	2BQ12@1|root,319E3@2|Bacteria,1Q2GE@1224|Proteobacteria,42VNB@68525|delta/epsilon subdivisions,2YQEY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_86363_3	709032.Sulku_1035	3.43e-49	162.0	COG2353@1|root,COG2353@2|Bacteria,1N4PP@1224|Proteobacteria,42U5U@68525|delta/epsilon subdivisions,2YQF5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
k59_153097_1	159087.Daro_0456	5.41e-71	226.0	COG2610@1|root,COG2610@2|Bacteria,1N2VU@1224|Proteobacteria,2VHB5@28216|Betaproteobacteria,2KYC4@206389|Rhodocyclales	206389|Rhodocyclales	EG	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_684908_1	1537917.JU82_02235	1.18e-57	189.0	COG0577@1|root,COG0577@2|Bacteria,1QT4V@1224|Proteobacteria,42P7K@68525|delta/epsilon subdivisions,2YNGD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	ABC transporter permease	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
k59_684908_2	1120954.ATXE01000002_gene750	1e-06	51.2	COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,4DNTI@85009|Propionibacteriales	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	gluA	-	3.6.3.21	ko:K02028,ko:K10008	ko02010,map02010	M00233,M00236	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.9	-	-	ABC_tran
k59_1090103_1	76114.ebA3657	1.89e-08	53.9	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,2VQ3U@28216|Betaproteobacteria,2KW42@206389|Rhodocyclales	206389|Rhodocyclales	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
k59_1090103_2	159087.Daro_4064	2.75e-83	253.0	COG0697@1|root,COG0697@2|Bacteria,1MXCD@1224|Proteobacteria,2VMQB@28216|Betaproteobacteria,2KUKE@206389|Rhodocyclales	206389|Rhodocyclales	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_1152387_1	1537917.JU82_09915	5.54e-66	209.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,42N10@68525|delta/epsilon subdivisions,2YMIF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	LU	DNA processing protein	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
k59_1792171_1	1537917.JU82_04675	7.16e-37	128.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,42R5H@68525|delta/epsilon subdivisions,2YNYJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
k59_1792171_2	1249480.B649_08255	9.7e-35	127.0	COG1729@1|root,COG1729@2|Bacteria,1NG81@1224|Proteobacteria,42R1Z@68525|delta/epsilon subdivisions,2YNY7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	repeat protein	ybgF	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_6
k59_1734023_1	1123517.JOMR01000001_gene1614	6.28e-08	53.9	COG2199@1|root,COG2199@2|Bacteria,1NYG9@1224|Proteobacteria,1RV5M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Protoglobin
k59_1734023_2	387093.SUN_1063	4.69e-117	346.0	COG0803@1|root,COG0803@2|Bacteria,1MVW9@1224|Proteobacteria,42MBX@68525|delta/epsilon subdivisions,2YNB0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	periplasmic solute binding protein	znuA	-	-	ko:K02077,ko:K09815	ko02010,map02010	M00242,M00244	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ZinT,ZnuA
k59_1565058_1	94122.Shewana3_0810	1.12e-21	94.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,2Q9WW@267890|Shewanellaceae	1236|Gammaproteobacteria	JKL	DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k59_1565058_2	1165841.SULAR_04087	1.16e-36	129.0	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,42N5N@68525|delta/epsilon subdivisions,2YMVJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
k59_1616691_2	159087.Daro_1508	6.08e-92	270.0	2DBX8@1|root,2ZBN7@2|Bacteria,1RABM@1224|Proteobacteria,2VQYS@28216|Betaproteobacteria,2KWCX@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function, DUF269	-	-	-	-	-	-	-	-	-	-	-	-	DUF269
k59_1616691_3	580332.Slit_0908	2.53e-33	115.0	2DQ5Y@1|root,334WI@2|Bacteria,1QWGA@1224|Proteobacteria,2VWW1@28216|Betaproteobacteria,44WJN@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Rop-like	-	-	-	-	-	-	-	-	-	-	-	-	Rop-like
k59_1616691_4	768671.ThimaDRAFT_4661	8.05e-21	86.3	COG1146@1|root,COG1146@2|Bacteria,1QW5F@1224|Proteobacteria,1T4WS@1236|Gammaproteobacteria,1WYJJ@135613|Chromatiales	135613|Chromatiales	C	TIGRFAM ferredoxin III	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
k59_1565068_1	709032.Sulku_0332	4.19e-55	180.0	COG1587@1|root,COG1587@2|Bacteria,1NMTP@1224|Proteobacteria,42T0U@68525|delta/epsilon subdivisions,2YPN4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Uroporphyrinogen-III synthase	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
k59_43396_1	1304883.KI912532_gene1755	1.94e-132	393.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VH4J@28216|Betaproteobacteria,2KUGP@206389|Rhodocyclales	206389|Rhodocyclales	S	ABC transporter	abcZ	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
k59_1873179_1	485917.Phep_3933	1.66e-93	285.0	COG0037@1|root,COG0037@2|Bacteria,4NIZR@976|Bacteroidetes,1IZJG@117747|Sphingobacteriia	976|Bacteroidetes	D	LPS biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	NAD_synthase
k59_100047_1	709032.Sulku_1649	5.43e-26	100.0	COG1051@1|root,COG1051@2|Bacteria,1PNK8@1224|Proteobacteria,42YE5@68525|delta/epsilon subdivisions,2YR8Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	NUDIX domain	-	-	3.6.1.62,3.6.1.64	ko:K16855	ko00230,ko03018,map00230,map03018	-	R00961,R10235,R10815	RC00002	ko00000,ko00001,ko01000,ko03019	-	-	-	NUDIX
k59_1581866_1	1249480.B649_06480	1.95e-27	110.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42PMU@68525|delta/epsilon subdivisions,2YNHE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4
k59_1581866_2	709032.Sulku_2176	8.94e-26	106.0	COG4206@1|root,COG4206@2|Bacteria,1QUPS@1224|Proteobacteria,43CID@68525|delta/epsilon subdivisions,2YTCZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_1514398_1	709032.Sulku_1375	5.53e-110	327.0	COG2223@1|root,COG2223@2|Bacteria,1MU27@1224|Proteobacteria,42PGA@68525|delta/epsilon subdivisions,2YMBC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG2223 Nitrate nitrite transporter	-	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1
k59_281190_2	525898.Sdel_0979	4.11e-07	53.1	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YM96@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	cmeF	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_1463040_1	1172190.M947_07155	3.04e-14	71.6	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,42M80@68525|delta/epsilon subdivisions,2YMEN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
k59_1463040_2	983545.Glaag_4076	7.28e-25	103.0	COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,1RNDE@1236|Gammaproteobacteria,465KF@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
k59_1519100_2	85643.Tmz1t_3914	4.14e-36	125.0	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,2VUC8@28216|Betaproteobacteria,2KX0I@206389|Rhodocyclales	206389|Rhodocyclales	P	protein involved in tolerance to divalent cations	cutA1	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
k59_1519100_3	1304883.KI912532_gene858	2.75e-29	115.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,2VI8I@28216|Betaproteobacteria,2KV4F@206389|Rhodocyclales	206389|Rhodocyclales	CO	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
k59_461129_1	573064.Mefer_0807	1.11e-14	74.3	COG1051@1|root,arCOG01075@2157|Archaea,2XXS4@28890|Euryarchaeota,23R1E@183939|Methanococci	183939|Methanococci	F	PFAM NUDIX hydrolase	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
k59_1694358_1	1249480.B649_11140	4.51e-21	86.7	COG2952@1|root,COG2952@2|Bacteria,1PBRU@1224|Proteobacteria,42MEP@68525|delta/epsilon subdivisions,2YN8A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09804	-	-	-	-	ko00000	-	-	-	DUF507
k59_1694358_2	1537917.JU82_02130	1.19e-255	702.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,42KZG@68525|delta/epsilon subdivisions,2YMKQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
k59_997588_1	395494.Galf_2569	9.08e-105	315.0	COG3287@1|root,COG3287@2|Bacteria,1QUQH@1224|Proteobacteria,2VMN2@28216|Betaproteobacteria,44WBJ@713636|Nitrosomonadales	28216|Betaproteobacteria	S	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
k59_1291460_1	653733.Selin_1142	2.65e-17	87.4	COG2202@1|root,COG2203@1|root,COG5000@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG5000@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.1.1.80,2.7.13.3,2.7.8.41,3.1.1.61	ko:K07716,ko:K08744,ko:K13598,ko:K13924	ko00564,ko01100,ko02020,ko02030,ko04112,map00564,map01100,map02020,map02030,map04112	M00498,M00506,M00511	R02030	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg,SpoIIE
k59_1638066_2	1249480.B649_04885	1.25e-48	170.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,42MV3@68525|delta/epsilon subdivisions,2YNP4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
k59_523611_1	1121035.AUCH01000006_gene606	7.52e-35	135.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,1NWNJ@1224|Proteobacteria,2WGSC@28216|Betaproteobacteria,2KVJK@206389|Rhodocyclales	206389|Rhodocyclales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_3,PAS_4
k59_103590_1	1249480.B649_08735	2.83e-63	209.0	COG1450@1|root,COG1450@2|Bacteria,1MVNC@1224|Proteobacteria,43BJ2@68525|delta/epsilon subdivisions,2YN49@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Type II and III secretion system protein	ctsD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	STN,Secretin,Secretin_N_2
k59_1877934_1	1286631.X805_07670	9.42e-18	90.9	COG2304@1|root,COG2373@1|root,COG2931@1|root,COG2304@2|Bacteria,COG2373@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2VKA9@28216|Betaproteobacteria,1KK67@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	TIGRFAM outer membrane adhesin like proteiin	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4347,He_PIG,HemolysinCabind,VWA_2
k59_1638106_1	709032.Sulku_0019	7.98e-133	392.0	COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,42RCJ@68525|delta/epsilon subdivisions,2YNX9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG4775 Outer membrane protein protective antigen OMA87	-	-	-	ko:K07278	-	-	-	-	ko00000,ko02000	1.B.33.2.4	-	-	Bac_surface_Ag,POTRA
k59_935585_1	1537917.JU82_03745	1.91e-77	231.0	COG0781@1|root,COG0781@2|Bacteria,1N94P@1224|Proteobacteria,42SEA@68525|delta/epsilon subdivisions,2YPFW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
k59_935585_2	709032.Sulku_0315	2.27e-05	45.4	COG1060@1|root,COG1060@2|Bacteria,1MX50@1224|Proteobacteria,42M6U@68525|delta/epsilon subdivisions,2YN4H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnC	-	1.21.98.1	ko:K11784	ko00130,ko01110,map00130,map01110	-	R08588	RC02329	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
k59_642754_1	1537917.JU82_09695	1.43e-84	252.0	2994D@1|root,2ZW7V@2|Bacteria,1Q2D1@1224|Proteobacteria,42VGB@68525|delta/epsilon subdivisions,2YQM6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_642754_2	709032.Sulku_0645	6.81e-56	179.0	COG0169@1|root,COG0169@2|Bacteria,1Q1X7@1224|Proteobacteria,431CA@68525|delta/epsilon subdivisions,2YSA4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	-	-	-	-	-	-	-	-	-	-	-	-	Shikimate_dh_N
k59_1109333_2	709032.Sulku_0977	5.04e-84	257.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,42M5Y@68525|delta/epsilon subdivisions,2YMJB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
k59_746405_2	387093.SUN_0856	1.33e-58	197.0	COG1001@1|root,COG1001@2|Bacteria,1MVFP@1224|Proteobacteria,42NWX@68525|delta/epsilon subdivisions,2YR28@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Adenine deaminase C-terminal domain	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
k59_523656_1	387093.SUN_0809	6.11e-118	343.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,42M0X@68525|delta/epsilon subdivisions,2YN2X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
k59_523656_2	387093.SUN_0808	3.34e-72	223.0	COG1028@1|root,COG1028@2|Bacteria,1MU73@1224|Proteobacteria,42KZK@68525|delta/epsilon subdivisions,2YMUM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	IQ	dehydrogenase	hdhA	-	1.1.1.159	ko:K00076	ko00121,map00121	-	-	-	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
k59_818207_1	1123393.KB891316_gene1282	5.01e-133	397.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k59_818207_2	1123393.KB891316_gene1283	7.54e-26	107.0	29Y2F@1|root,30JVD@2|Bacteria,1RAWX@1224|Proteobacteria,2VSM0@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_870984_1	709032.Sulku_1467	3.63e-45	157.0	COG0642@1|root,COG5000@1|root,COG0642@2|Bacteria,COG5000@2|Bacteria,1N5IQ@1224|Proteobacteria,42N7Z@68525|delta/epsilon subdivisions,2YN64@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
k59_870984_2	709032.Sulku_1941	1.54e-71	226.0	2CHQX@1|root,33W06@2|Bacteria,1NWMC@1224|Proteobacteria,42V4N@68525|delta/epsilon subdivisions	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1467249_1	1537917.JU82_01575	6.01e-32	122.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,42M1X@68525|delta/epsilon subdivisions,2YMQ9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	acetolactate synthase	ilvI	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_1109370_1	709032.Sulku_0708	4.53e-37	130.0	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,42N5N@68525|delta/epsilon subdivisions,2YMVJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
k59_1638183_1	1165841.SULAR_08904	2.19e-113	328.0	COG3381@1|root,COG3381@2|Bacteria,1N4MX@1224|Proteobacteria,42RVB@68525|delta/epsilon subdivisions,2YP5X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	component of anaerobic	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_del
k59_1519262_1	95619.PM1_0215880	1.8e-97	296.0	COG3385@1|root,COG3385@2|Bacteria,1R7HV@1224|Proteobacteria,1T0ER@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Domain of unknown function (DUF4372)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
k59_1519279_2	1249480.B649_01235	1.11e-90	268.0	2BS7I@1|root,30SN1@2|Bacteria,1Q8VY@1224|Proteobacteria,42VZW@68525|delta/epsilon subdivisions,2YQMJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1224932_1	709032.Sulku_0059	1.33e-83	250.0	COG1714@1|root,COG1714@2|Bacteria,1N2TA@1224|Proteobacteria	1224|Proteobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
k59_1109429_1	1123517.JOMR01000001_gene1180	4.22e-79	259.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,1RMPC@1236|Gammaproteobacteria,461R1@72273|Thiotrichales	72273|Thiotrichales	O	Belongs to the peptidase S16 family	-	-	-	ko:K04770	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AAA_32,Lon_C
k59_523772_1	159087.Daro_3764	3.05e-52	176.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,2VJ1J@28216|Betaproteobacteria,2KVRB@206389|Rhodocyclales	206389|Rhodocyclales	U	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	czcD1	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
k59_339278_2	709032.Sulku_1386	6.39e-68	207.0	2AHT8@1|root,3185S@2|Bacteria,1RH98@1224|Proteobacteria,42RJ9@68525|delta/epsilon subdivisions,2YP9K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_400804_2	709032.Sulku_2333	2.95e-31	115.0	COG0546@1|root,COG0546@2|Bacteria,1RBMZ@1224|Proteobacteria,42RG3@68525|delta/epsilon subdivisions,2YP44@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Hydrolase	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_1225002_1	765913.ThidrDRAFT_3654	1.82e-45	164.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RSD8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
k59_1694591_1	1249480.B649_06360	0.00037	42.4	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,42MQD@68525|delta/epsilon subdivisions,2YNN1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Sulfate permease	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k59_1694591_2	1168067.JAGP01000001_gene570	4.05e-49	169.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,Response_reg
k59_1694600_1	709032.Sulku_0074	3.07e-98	292.0	COG0679@1|root,COG0679@2|Bacteria,1N5NC@1224|Proteobacteria,42PYE@68525|delta/epsilon subdivisions,2YMUI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM Auxin Efflux Carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
k59_1174019_1	1453501.JELR01000001_gene2490	2.44e-25	108.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,1RMS8@1236|Gammaproteobacteria,4657M@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	slt	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009274,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	iETEC_1333.ETEC_4747,iPC815.YPO0452	SLT,SLT_L
k59_173129_1	1249480.B649_10500	1.27e-92	282.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,42MM1@68525|delta/epsilon subdivisions,2YN3A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	8-amino-7-oxononanoate synthase	bioF	-	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_400845_1	1165841.SULAR_07790	8.6e-32	116.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42PA1@68525|delta/epsilon subdivisions,2YNMR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_400845_2	1165841.SULAR_07765	9.54e-31	117.0	COG0226@1|root,COG0226@2|Bacteria,1MUAZ@1224|Proteobacteria,42NM3@68525|delta/epsilon subdivisions,2YMMK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
k59_818392_1	205922.Pfl01_0759	1.29e-24	99.4	COG2913@1|root,COG2913@2|Bacteria,1N6YW@1224|Proteobacteria,1SCTT@1236|Gammaproteobacteria,1YPBJ@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamE	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0030674,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042221,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045203,GO:0045229,GO:0046677,GO:0050896,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0060090,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063	-	ko:K06186	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	SmpA_OmlA
k59_818392_2	981336.F944_02135	1.9e-14	69.3	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,1S4H7@1236|Gammaproteobacteria,3NKJ7@468|Moraxellaceae	1236|Gammaproteobacteria	K	Belongs to the Fur family	fur	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043167,GO:0043169,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046872,GO:0046914,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
k59_400885_1	709032.Sulku_1244	3.32e-130	379.0	COG0842@1|root,COG0842@2|Bacteria,1NG32@1224|Proteobacteria,43APA@68525|delta/epsilon subdivisions,2YT2R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_3
k59_227632_1	159087.Daro_2518	3.64e-149	427.0	COG1721@1|root,COG1721@2|Bacteria,1R3QD@1224|Proteobacteria,2VN9P@28216|Betaproteobacteria,2KW8Q@206389|Rhodocyclales	206389|Rhodocyclales	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k59_643074_1	709032.Sulku_0365	2.99e-89	273.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,42MUZ@68525|delta/epsilon subdivisions,2YMR3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_461447_1	1234364.AMSF01000027_gene3482	5.07e-75	233.0	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,1RNN8@1236|Gammaproteobacteria,1X3I8@135614|Xanthomonadales	135614|Xanthomonadales	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
k59_523911_2	1537917.JU82_09795	4.18e-11	62.4	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,42N30@68525|delta/epsilon subdivisions,2YMCR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
k59_1225111_1	1537917.JU82_11260	2.38e-112	329.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,42N5Q@68525|delta/epsilon subdivisions,2YMRK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
k59_1519513_1	1537917.JU82_11495	1.99e-97	286.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,42NR9@68525|delta/epsilon subdivisions,2YN03@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
k59_47660_1	981336.F944_03056	4.32e-117	351.0	COG3845@1|root,COG3845@2|Bacteria,1NT0H@1224|Proteobacteria,1T1GV@1236|Gammaproteobacteria,3NJ3U@468|Moraxellaceae	1236|Gammaproteobacteria	S	ABC transporter	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
k59_1341895_1	387093.SUN_1232	4.94e-104	319.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,42N50@68525|delta/epsilon subdivisions,2YN1V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
k59_173250_1	709032.Sulku_1030	2.36e-56	176.0	COG1605@1|root,COG1605@2|Bacteria,1N6UE@1224|Proteobacteria,42UUU@68525|delta/epsilon subdivisions,2YQ49@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Chorismate mutase	-	-	4.2.99.21	ko:K04782	ko01053,ko01110,ko01130,map01053,map01110,map01130	-	R06602	RC01549,RC02148	ko00000,ko00001,ko01000	-	-	-	CM_2
k59_339436_2	387092.NIS_0032	3.04e-137	402.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,42Q9B@68525|delta/epsilon subdivisions,2YNKN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FCSD-flav_bind,Pyr_redox_2
k59_643149_1	1537917.JU82_03175	1.47e-111	328.0	COG1847@1|root,COG1847@2|Bacteria,1RB1P@1224|Proteobacteria,42QYV@68525|delta/epsilon subdivisions,2YNW5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Jag_N	-	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N
k59_1225158_1	395494.Galf_1323	4.14e-45	167.0	COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,2VH7P@28216|Betaproteobacteria,44V8A@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_1519581_2	1150621.SMUL_3178	2.53e-33	117.0	2ENSD@1|root,33GDJ@2|Bacteria,1NGWW@1224|Proteobacteria,42UG8@68525|delta/epsilon subdivisions,2YQJ1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1341940_1	709032.Sulku_0028	2.63e-62	200.0	COG2334@1|root,COG2334@2|Bacteria,1MUKJ@1224|Proteobacteria,42X9G@68525|delta/epsilon subdivisions,2YQEF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	homoserine kinase type II (Protein kinase fold)	-	-	2.7.1.39	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
k59_1341940_2	1537917.JU82_00690	2.6e-107	313.0	COG0778@1|root,COG0778@2|Bacteria,1MZN8@1224|Proteobacteria,43ATV@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	TIGRFAM cob(II)yrinic acid a,c-diamide reductase	bluB	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016491,GO:0016705,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.13.11.79	ko:K04719	ko00740,ko01100,map00740,map01100	-	R09083	RC00435,RC02413	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
k59_1341940_3	1537917.JU82_00685	4.29e-97	294.0	COG1797@1|root,COG1797@2|Bacteria,1MV7Z@1224|Proteobacteria,42M8T@68525|delta/epsilon subdivisions	1224|Proteobacteria	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_0470	AAA_26,CbiA,GATase_3
k59_286811_1	1165841.SULAR_01350	3.33e-78	255.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2YMQV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_1694782_1	1366050.N234_25070	1.41e-32	120.0	COG2186@1|root,COG2186@2|Bacteria,1R68P@1224|Proteobacteria,2VK2A@28216|Betaproteobacteria	1224|Proteobacteria	K	Regulatory protein GntR HTH	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
k59_1694782_2	1122612.AUBA01000015_gene882	7.42e-19	85.5	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,2JZVD@204457|Sphingomonadales	204457|Sphingomonadales	C	belongs to the aldehyde dehydrogenase family	-	-	1.2.1.39	ko:K00146	ko00360,ko00643,ko01100,ko01120,map00360,map00643,map01100,map01120	-	R02536	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
k59_1519630_2	709032.Sulku_1541	6.44e-63	201.0	COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,42QA8@68525|delta/epsilon subdivisions,2YNH6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_3
k59_461568_1	1160707.AJIK01000008_gene860	1.29e-36	137.0	COG3980@1|root,COG3980@2|Bacteria,1U2ZW@1239|Firmicutes,4HDTP@91061|Bacilli,26FBT@186818|Planococcaceae	91061|Bacilli	M	spore coat polysaccharide biosynthesis protein	spsG	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C
k59_47749_1	768670.Calni_1797	1.07e-55	185.0	COG0399@1|root,COG0399@2|Bacteria,2GETS@200930|Deferribacteres	2|Bacteria	E	Belongs to the DegT DnrJ EryC1 family	spsC	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
k59_1342012_1	709032.Sulku_1954	7.69e-87	278.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2YNQA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
k59_104048_1	159087.Daro_2469	9.06e-70	217.0	COG3132@1|root,COG3132@2|Bacteria,1RA13@1224|Proteobacteria,2VQGS@28216|Betaproteobacteria,2KWEA@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the UPF0502 family	-	-	-	ko:K09915	-	-	-	-	ko00000	-	-	-	DUF480
k59_461605_1	1165841.SULAR_10324	6.56e-68	220.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1RGCV@1224|Proteobacteria,42M47@68525|delta/epsilon subdivisions,2YMRS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	(EAL) domain protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_1346302_1	709032.Sulku_0748	1.64e-125	365.0	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,42M40@68525|delta/epsilon subdivisions,2YMGX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
k59_405358_1	159087.Daro_0900	2.14e-214	596.0	COG0683@1|root,COG0683@2|Bacteria,1MXR4@1224|Proteobacteria,2W054@28216|Betaproteobacteria,2KY0V@206389|Rhodocyclales	206389|Rhodocyclales	E	Receptor family ligand binding region	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
k59_1523157_1	709032.Sulku_1185	2.87e-126	383.0	COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,42M43@68525|delta/epsilon subdivisions,2YM8G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the aconitase IPM isomerase family	acnB	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0045333,GO:0046395,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072329,GO:0072350,GO:0097159,GO:1901363,GO:1901575	4.2.1.3,4.2.1.99	ko:K01682	ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173	R01324,R01325,R01900,R04425	RC00497,RC00498,RC00618,RC01153	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_2_N,Aconitase_B_N
k59_1527800_1	159087.Daro_2172	1.54e-28	110.0	COG3520@1|root,COG3520@2|Bacteria,1MWVS@1224|Proteobacteria,2VIPW@28216|Betaproteobacteria,2KX6Y@206389|Rhodocyclales	206389|Rhodocyclales	S	Type VI secretion, TssG	-	-	-	ko:K11895	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_TssG
k59_1527800_2	159087.Daro_2173	3.31e-72	233.0	COG3519@1|root,COG3519@2|Bacteria,1MUY4@1224|Proteobacteria,2VHXS@28216|Betaproteobacteria,2KWBQ@206389|Rhodocyclales	206389|Rhodocyclales	S	Type VI secretion system, TssF	-	-	-	ko:K11896	-	M00334	-	-	ko00000,ko00002,ko02044	3.A.23.1	-	-	T6SS_TssF
k59_1468567_1	395494.Galf_0145	1.84e-94	298.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,2VIJ7@28216|Betaproteobacteria,44V59@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_C
k59_999267_1	709032.Sulku_1746	6.77e-31	118.0	COG0457@1|root,COG0457@2|Bacteria,1Q55C@1224|Proteobacteria,42RCA@68525|delta/epsilon subdivisions,2YND3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	PPR
k59_236087_1	929558.SMGD1_0330	3.7e-14	70.9	COG0388@1|root,COG0388@2|Bacteria,1QBMA@1224|Proteobacteria,42PD8@68525|delta/epsilon subdivisions,2YMD1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	hydrolase	-	-	3.5.5.1	ko:K01501	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
k59_236087_2	1537917.JU82_04825	2.66e-28	102.0	COG1722@1|root,COG1722@2|Bacteria,1Q35M@1224|Proteobacteria,42WTB@68525|delta/epsilon subdivisions,2YQRG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
k59_236087_3	1249480.B649_08145	1.08e-131	381.0	COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,42N1M@68525|delta/epsilon subdivisions,2YN3T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metXA	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
k59_1175484_1	387093.SUN_1816	5.78e-140	415.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2YN8I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Abc transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
k59_1175484_2	1165841.SULAR_05888	3.47e-29	105.0	COG4728@1|root,COG4728@2|Bacteria,1N6NP@1224|Proteobacteria,42WCY@68525|delta/epsilon subdivisions,2YSK3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF1653)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1653
k59_1762416_1	192222.Cj1444c	8.75e-37	138.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,42M62@68525|delta/epsilon subdivisions,2YMKY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Capsular polysaccharide ABC transporter, periplasmic polysaccharide-binding protein	kpsD	-	-	-	-	-	-	-	-	-	-	-	Poly_export,SLBB
k59_1762416_2	765910.MARPU_00950	1.85e-07	53.1	COG4618@1|root,COG4618@2|Bacteria,1NTI5@1224|Proteobacteria,1T1HR@1236|Gammaproteobacteria,1X2NS@135613|Chromatiales	135613|Chromatiales	V	Type I secretion system	-	-	-	ko:K16299	ko02010,map02010	M00571	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.110.10	-	-	ABC_membrane,ABC_tran
k59_1527847_1	159087.Daro_3404	1.35e-118	351.0	COG3266@1|root,COG3267@1|root,COG3266@2|Bacteria,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,2VMD2@28216|Betaproteobacteria,2KVQP@206389|Rhodocyclales	206389|Rhodocyclales	U	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
k59_294689_1	1300150.EMQU_0434	1.24e-05	48.1	COG0210@1|root,COG0210@2|Bacteria,1VTAQ@1239|Firmicutes,4HTA9@91061|Bacilli,4B1K5@81852|Enterococcaceae	91061|Bacilli	L	UvrD-like helicase C-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_294689_2	387093.SUN_1105	2.56e-61	191.0	COG0537@1|root,COG0537@2|Bacteria,1MZVD@1224|Proteobacteria,42TMC@68525|delta/epsilon subdivisions,2YPSJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	FG	(HIT) family	-	-	-	-	-	-	-	-	-	-	-	-	HIT
k59_1234128_1	1304883.KI912532_gene704	1.1e-46	158.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,2VH51@28216|Betaproteobacteria,2KU9W@206389|Rhodocyclales	206389|Rhodocyclales	O	Peptidase U32	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
k59_1234128_2	1304883.KI912532_gene705	9.26e-103	303.0	COG0826@1|root,COG0826@2|Bacteria,1MWFW@1224|Proteobacteria,2VISF@28216|Betaproteobacteria,2KUYD@206389|Rhodocyclales	206389|Rhodocyclales	O	Peptidase family U32	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_U32
k59_1468607_1	909663.KI867150_gene807	3.36e-78	245.0	COG0674@1|root,COG0674@2|Bacteria,1MWCI@1224|Proteobacteria,42NJY@68525|delta/epsilon subdivisions,2WIW3@28221|Deltaproteobacteria,2MQ5X@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Pyruvate:ferredoxin oxidoreductase core domain II	-	-	1.2.7.11,1.2.7.3,1.2.7.7	ko:K00174,ko:K00186	ko00010,ko00020,ko00280,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197,R07160,R08566,R08567	RC00004,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
k59_1057762_1	1537917.JU82_03855	1.34e-134	397.0	COG1463@1|root,COG1463@2|Bacteria,1RFFS@1224|Proteobacteria,42P4P@68525|delta/epsilon subdivisions,2YNNZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
k59_1057762_2	709032.Sulku_0337	5.74e-183	530.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,42MTZ@68525|delta/epsilon subdivisions,2YMPF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
k59_1116430_1	1168067.JAGP01000001_gene2149	3.83e-76	250.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,1RNB2@1236|Gammaproteobacteria,45ZT1@72273|Thiotrichales	72273|Thiotrichales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_177183_1	748247.AZKH_3254	3.4e-08	55.8	COG3287@1|root,COG3287@2|Bacteria,1QUQH@1224|Proteobacteria,2VMN2@28216|Betaproteobacteria,2KUGW@206389|Rhodocyclales	206389|Rhodocyclales	S	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
k59_177183_2	1304888.ATWF01000001_gene1234	1.32e-27	111.0	COG3437@1|root,COG3437@2|Bacteria,2GFDI@200930|Deferribacteres	2|Bacteria	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
k59_1703757_1	1249480.B649_11615	7.32e-12	64.3	COG0803@1|root,COG0803@2|Bacteria,1MVW9@1224|Proteobacteria,42MBX@68525|delta/epsilon subdivisions,2YQ8H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the bacterial solute-binding protein 9 family	-	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
k59_1703757_2	1249480.B649_11610	1.59e-136	391.0	COG1121@1|root,COG1121@2|Bacteria,1MUDW@1224|Proteobacteria,42NI8@68525|delta/epsilon subdivisions,2YMKV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	ABC transporter	-	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
k59_1703757_3	1249480.B649_11605	2.38e-140	402.0	COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,42MYM@68525|delta/epsilon subdivisions,2YMMF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Abc transporter	-	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
k59_1703757_4	563040.Saut_2134	0.000831	41.2	COG4106@1|root,COG4106@2|Bacteria,1QZ2S@1224|Proteobacteria,43CEU@68525|delta/epsilon subdivisions,2YTCB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Methyltransferase domain	-	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
k59_1762446_2	709032.Sulku_0008	3.78e-174	488.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,42N2N@68525|delta/epsilon subdivisions,2YN3F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3708
k59_1762446_3	709032.Sulku_0009	1.03e-222	626.0	COG0617@1|root,COG1418@1|root,COG0617@2|Bacteria,COG1418@2|Bacteria,1MU2X@1224|Proteobacteria,42MJJ@68525|delta/epsilon subdivisions,2YMGU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	tRNA nucleotidyltransferase poly(A) polymerase	cca	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
k59_1762446_4	709032.Sulku_0010	1.22e-44	157.0	COG0642@1|root,COG2205@2|Bacteria,1QUJ7@1224|Proteobacteria,43BJF@68525|delta/epsilon subdivisions,2YNM7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,sCache_like
k59_1703766_1	709032.Sulku_0545	2.09e-155	437.0	COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,42P58@68525|delta/epsilon subdivisions,2YN3D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	GO:0003674,GO:0005488,GO:0005515,GO:0042802	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
k59_60053_1	1249480.B649_09230	1.93e-107	320.0	COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,42MVB@68525|delta/epsilon subdivisions,2YNU4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	O-acetylhomoserine sulfhydrylase	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
k59_1843_1	1537917.JU82_03420	1.66e-148	443.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,42KZI@68525|delta/epsilon subdivisions,2YR60@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Domain of unknown function (DUF3458_C) ARM repeats	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,Peptidase_M1
k59_1762479_1	1249480.B649_07585	6.43e-43	145.0	COG0693@1|root,COG0693@2|Bacteria,1N7T2@1224|Proteobacteria,42RGX@68525|delta/epsilon subdivisions,2YPA8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	TIGRFAM DJ-1 family protein	thiJ	-	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
k59_471124_1	572477.Alvin_1054	5.83e-41	153.0	COG0784@1|root,COG2198@1|root,COG4251@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG4251@2|Bacteria,1NC9X@1224|Proteobacteria,1SVEC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_9,Response_reg
k59_471124_2	1304883.KI912532_gene2540	8.84e-23	95.9	COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,2VI7B@28216|Betaproteobacteria,2KVNM@206389|Rhodocyclales	206389|Rhodocyclales	F	Belongs to the dGTPase family. Type 2 subfamily	dgt1	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
k59_1703815_1	1172190.M947_01315	2.48e-143	421.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,42M4S@68525|delta/epsilon subdivisions,2YM8Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	hydB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.12.5.1	ko:K05922	-	-	-	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
k59_1468684_1	159087.Daro_1799	2.55e-135	397.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VHES@28216|Betaproteobacteria,2KU7H@206389|Rhodocyclales	206389|Rhodocyclales	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	-	-	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
k59_999403_1	1249480.B649_04040	3.76e-82	264.0	COG0715@1|root,COG0834@1|root,COG2199@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42MCD@68525|delta/epsilon subdivisions,2YN6K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	ET	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,NMT1,SBP_bac_3
k59_1409999_1	979533.F1D0V1_9CAUD	2.71e-34	130.0	4QGAG@10239|Viruses,4R0KB@35237|dsDNA viruses  no RNA stage,4QUA4@28883|Caudovirales,4QNFP@10744|Podoviridae	10744|Podoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1409999_2	1123517.JOMR01000001_gene86	2.07e-26	105.0	COG1528@1|root,COG1528@2|Bacteria,1R9ZC@1224|Proteobacteria,1RYVB@1236|Gammaproteobacteria,4617E@72273|Thiotrichales	72273|Thiotrichales	P	Iron-storage protein	-	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
k59_1586540_1	709032.Sulku_1905	7.69e-92	283.0	COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,42N4Y@68525|delta/epsilon subdivisions,2YNCE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase,Methyltransf_11,Methyltransf_31
k59_1234236_1	1123518.ARWI01000001_gene1308	2.96e-20	97.8	COG0665@1|root,COG4121@1|root,COG0665@2|Bacteria,COG4121@2|Bacteria,1MZW5@1224|Proteobacteria,1RMTE@1236|Gammaproteobacteria,4609C@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34	mnmC	-	2.1.1.61	ko:K15461	-	-	R00601,R08702	RC00003,RC00053,RC00060,RC01483	ko00000,ko01000,ko03016	-	-	-	DAO,Methyltransf_30
k59_1234236_2	1122212.AULO01000011_gene426	2.26e-39	138.0	COG0788@1|root,COG0788@2|Bacteria,1MVCF@1224|Proteobacteria,1RN6Q@1236|Gammaproteobacteria,1XHRP@135619|Oceanospirillales	135619|Oceanospirillales	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT,Formyl_trans_N
k59_1351411_1	387093.SUN_1893	9.47e-98	292.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,42NCJ@68525|delta/epsilon subdivisions,2YMQJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
k59_1351411_2	387093.SUN_1892	3.69e-44	149.0	COG1587@1|root,COG1587@2|Bacteria,1NMTP@1224|Proteobacteria,42T0U@68525|delta/epsilon subdivisions,2YPN4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Uroporphyrinogen-III synthase	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
k59_1821562_1	159087.Daro_3990	1.21e-35	136.0	COG0517@1|root,COG2203@1|root,COG3829@1|root,COG5001@1|root,COG0517@2|Bacteria,COG2203@2|Bacteria,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KUCK@206389|Rhodocyclales	206389|Rhodocyclales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CZB,EAL,GAF_2,GGDEF,PAS_4,PAS_9
k59_1821562_2	159087.Daro_3989	3.78e-36	131.0	COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,2VK03@28216|Betaproteobacteria,2KV18@206389|Rhodocyclales	206389|Rhodocyclales	C	NiFe/NiFeSe hydrogenase small subunit C-terminal	-	-	1.12.99.6	ko:K06282	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6
k59_177262_1	1304883.KI912532_gene473	3.72e-16	75.9	COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,2VHSD@28216|Betaproteobacteria,2KVE2@206389|Rhodocyclales	206389|Rhodocyclales	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
k59_177262_2	1304883.KI912532_gene474	2.95e-59	183.0	COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,2VU1C@28216|Betaproteobacteria,2KWRX@206389|Rhodocyclales	206389|Rhodocyclales	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
k59_1410032_2	1249480.B649_11255	7.23e-99	305.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,42MEI@68525|delta/epsilon subdivisions,2YN3Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Asparagine synthase, glutamine-hydrolyzing	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_412346_1	159087.Daro_1144	1.04e-41	141.0	COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,2VRAI@28216|Betaproteobacteria,2KW74@206389|Rhodocyclales	206389|Rhodocyclales	NT	Chemotaxis signal transduction protein	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
k59_294813_1	1537917.JU82_06325	4.35e-125	361.0	COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,42MJU@68525|delta/epsilon subdivisions,2YM7H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	UTP-glucose-1-phosphate uridylyltransferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0646	NTP_transferase
k59_1821588_1	1249480.B649_10840	4.59e-174	493.0	COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,42MGS@68525|delta/epsilon subdivisions,2YMUK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
k59_588452_1	159087.Daro_4121	1.3e-234	682.0	COG0247@1|root,COG0277@1|root,COG0479@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,COG0479@2|Bacteria,1MU43@1224|Proteobacteria,2VHYU@28216|Betaproteobacteria,2KUWB@206389|Rhodocyclales	206389|Rhodocyclales	C	FAD linked oxidase	-	-	-	-	-	-	-	-	-	-	-	-	CCG,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_8
k59_236275_1	1249480.B649_10610	2.78e-87	273.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2YNUU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	COG2804 Type II secretory pathway ATPase PulE Tfp pilus assembly pathway ATPase PilB	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
k59_118851_1	1000565.METUNv1_00369	1.19e-14	72.8	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,2VHHA@28216|Betaproteobacteria,2KUDS@206389|Rhodocyclales	206389|Rhodocyclales	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
k59_118851_2	159087.Daro_0931	1.92e-145	414.0	COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,2VIV0@28216|Betaproteobacteria,2KV3J@206389|Rhodocyclales	206389|Rhodocyclales	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	ppnK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
k59_1293005_1	1249480.B649_07380	1.89e-55	192.0	COG5001@1|root,COG5001@2|Bacteria,1QV5H@1224|Proteobacteria,42PV8@68525|delta/epsilon subdivisions,2YMZX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,LapD_MoxY_N
k59_353442_1	1165841.SULAR_06768	7.93e-74	246.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,42M5Q@68525|delta/epsilon subdivisions,2YM9V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
k59_118859_1	395493.BegalDRAFT_1973	1.68e-43	147.0	COG0625@1|root,COG0625@2|Bacteria,1MY47@1224|Proteobacteria,1S0SJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Glutathione S-Transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_N,GST_N_2,GST_N_3
k59_118859_2	159087.Daro_1459	4.44e-24	94.4	2BWYB@1|root,32W1H@2|Bacteria,1N1MW@1224|Proteobacteria,2VUU1@28216|Betaproteobacteria,2KX47@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_60159_1	62928.azo3101	2.04e-53	173.0	COG1959@1|root,COG1959@2|Bacteria,1N05H@1224|Proteobacteria,2VU41@28216|Betaproteobacteria,2KWK6@206389|Rhodocyclales	206389|Rhodocyclales	K	Transcriptional regulator	-	-	-	ko:K13771	ko05132,map05132	-	-	-	ko00000,ko00001,ko03000	-	-	-	Rrf2
k59_1410061_1	420662.Mpe_B0614	4.56e-78	256.0	COG1196@1|root,COG1322@1|root,COG1196@2|Bacteria,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,2VQQX@28216|Betaproteobacteria	28216|Betaproteobacteria	D	RmuC family	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
k59_353448_1	13037.EHJ79256	5.46e-06	49.3	COG0397@1|root,KOG2542@2759|Eukaryota,38CWY@33154|Opisthokonta,3BD16@33208|Metazoa,3CV30@33213|Bilateria,41VAN@6656|Arthropoda,3SKEN@50557|Insecta,441J7@7088|Lepidoptera	33208|Metazoa	S	Uncharacterized ACR, YdiU/UPF0061 family	-	-	-	-	-	-	-	-	-	-	-	-	UPF0061
k59_1764706_1	317025.Tcr_1825	3e-07	51.6	COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,1RMU0@1236|Gammaproteobacteria,45ZZM@72273|Thiotrichales	72273|Thiotrichales	H	Belongs to the prokaryotic GSH synthase family	gshB	-	6.3.2.3	ko:K01920	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00497,R10994	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	GSH-S_ATP,GSH-S_N
k59_1764706_2	203122.Sde_1762	2.31e-75	242.0	COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,1RNDE@1236|Gammaproteobacteria,464UV@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1,Thioredoxin_4
k59_943170_1	1565314.OA34_06910	1.77e-134	393.0	COG0715@1|root,COG0715@2|Bacteria,1MVJA@1224|Proteobacteria,42NMD@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	NMT1/THI5 like	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
k59_766083_1	1132855.KB913035_gene317	5.72e-121	358.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2VIG3@28216|Betaproteobacteria,2KKBX@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
k59_1706004_1	614083.AWQR01000003_gene2918	1.81e-20	90.1	COG2199@1|root,COG3706@2|Bacteria,1MXAW@1224|Proteobacteria,2VK79@28216|Betaproteobacteria,4ABKD@80864|Comamonadaceae	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	2.7.7.65	ko:K13590	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF
k59_1824302_1	395494.Galf_1869	7.62e-88	291.0	COG0715@1|root,COG0834@1|root,COG2199@1|root,COG3290@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG2199@2|Bacteria,COG3290@2|Bacteria,1RGCV@1224|Proteobacteria,2VK9Q@28216|Betaproteobacteria,44WPJ@713636|Nitrosomonadales	28216|Betaproteobacteria	T	SMART GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_4,PAS_9,SnoaL_3
k59_707472_2	563040.Saut_1517	1.29e-154	451.0	COG1070@1|root,COG1070@2|Bacteria,1MWS5@1224|Proteobacteria,43CSA@68525|delta/epsilon subdivisions,2YTM7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.189	ko:K11216	ko02024,map02024	-	R11183	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
k59_1412499_1	1249480.B649_01550	7.47e-18	75.9	COG0790@1|root,COG0790@2|Bacteria	2|Bacteria	S	beta-lactamase activity	enhC	-	-	ko:K07126,ko:K15474	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	Sel1
k59_1059919_1	1232437.KL662047_gene5225	6.18e-59	191.0	COG1028@1|root,COG1028@2|Bacteria,1MUBQ@1224|Proteobacteria,42S4I@68525|delta/epsilon subdivisions,2WNXV@28221|Deltaproteobacteria,2MNF8@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	fabG3	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_1824323_1	1165841.SULAR_02663	5e-54	187.0	COG0668@1|root,COG0668@2|Bacteria,1PMY3@1224|Proteobacteria,42M4K@68525|delta/epsilon subdivisions,2YMAQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
k59_1530679_1	1249480.B649_09600	6.75e-74	243.0	COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,42M3G@68525|delta/epsilon subdivisions,2YM8M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
k59_1059930_1	1537917.JU82_02300	6.58e-219	615.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,42N3P@68525|delta/epsilon subdivisions,2YM8F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EG	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
k59_121107_1	159087.Daro_2932	4.07e-121	361.0	COG1944@1|root,COG1944@2|Bacteria,1MV7K@1224|Proteobacteria,2VHZY@28216|Betaproteobacteria,2KV2Z@206389|Rhodocyclales	206389|Rhodocyclales	O	redox protein, regulator of disulfide bond formation	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	YcaO
k59_4904_1	159087.Daro_1934	2.44e-33	134.0	COG0784@1|root,COG3290@1|root,COG5002@1|root,COG0784@2|Bacteria,COG3290@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,2WGIN@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K20974	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_4,PAS_7,PAS_9,Response_reg,dCache_1
k59_355563_1	709032.Sulku_0836	1.4e-77	258.0	COG2202@1|root,COG2203@1|root,COG3452@1|root,COG5001@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3452@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YMHP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GGDEF,PAS_4,PAS_9
k59_1353548_1	709032.Sulku_0498	6.5e-83	249.0	COG0806@1|root,COG0806@2|Bacteria,1MYUH@1224|Proteobacteria,42SEN@68525|delta/epsilon subdivisions,2YPH6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
k59_62155_1	384765.SIAM614_08663	1.41e-16	77.4	COG1187@1|root,COG1187@2|Bacteria,1MU6M@1224|Proteobacteria,2TT86@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	rsuA	-	5.4.99.19	ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_62155_2	1165841.SULAR_09189	5.68e-79	244.0	COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,42N8K@68525|delta/epsilon subdivisions,2YN15@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Glycosyl hydrolase family 3	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidase_2,Glyco_hydro_3
k59_355566_2	159087.Daro_0117	2.94e-54	172.0	COG0721@1|root,COG0721@2|Bacteria,1MZQP@1224|Proteobacteria,2VUFB@28216|Betaproteobacteria,2KWWQ@206389|Rhodocyclales	206389|Rhodocyclales	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
k59_1065925_1	159087.Daro_0315	3.02e-99	289.0	COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,2VQ63@28216|Betaproteobacteria,2KVWF@206389|Rhodocyclales	206389|Rhodocyclales	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
k59_1711621_2	90814.KL370891_gene974	9.54e-99	299.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_9
k59_889919_1	62928.azo0437	6.64e-140	408.0	COG1027@1|root,COG1027@2|Bacteria,1R9JY@1224|Proteobacteria,2W02M@28216|Betaproteobacteria,2KV2S@206389|Rhodocyclales	206389|Rhodocyclales	E	Aspartate ammonia-lyase	aspA	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1
k59_184302_1	1123325.JHUV01000010_gene1186	1.19e-24	103.0	COG2199@1|root,COG2200@1|root,COG3829@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	yliE	GO:0003674,GO:0003824,GO:0008081,GO:0016787,GO:0016788,GO:0042578,GO:0071111	3.1.4.52	ko:K20964	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000	-	-	-	CHASE9,EAL,FIST,FIST_C,GGDEF,PAS,PAS_4,PAS_9
k59_184302_2	709032.Sulku_1053	7.13e-73	225.0	COG1648@1|root,COG1648@2|Bacteria,1RB3H@1224|Proteobacteria,42QT2@68525|delta/epsilon subdivisions,2YP97@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	COG1648 Siroheme synthase (precorrin-2 oxidase ferrochelatase domain)	-	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_7,Sirohm_synth_M
k59_360673_1	709032.Sulku_2376	1.69e-05	45.4	COG2203@1|root,COG2203@2|Bacteria,1R0Y5@1224|Proteobacteria,42NT7@68525|delta/epsilon subdivisions,2YRW5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF
k59_360673_2	709032.Sulku_2375	1.23e-99	291.0	COG2203@1|root,COG2203@2|Bacteria,1NT6X@1224|Proteobacteria,42XRB@68525|delta/epsilon subdivisions,2YRTW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF
k59_539519_1	497321.C664_10842	3.46e-36	132.0	COG0501@1|root,COG0501@2|Bacteria,1MUNA@1224|Proteobacteria,2VHTB@28216|Betaproteobacteria,2KVMZ@206389|Rhodocyclales	206389|Rhodocyclales	O	Peptidase M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
k59_1418974_1	709032.Sulku_1265	1.82e-132	396.0	COG1449@1|root,COG1449@2|Bacteria,1Q9WP@1224|Proteobacteria,42M42@68525|delta/epsilon subdivisions,2YMAK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	2.4.1.25	ko:K22451	ko00500,map00500	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH57	-	DUF1925,DUF1926,Glyco_hydro_57
k59_1477298_2	438753.AZC_3301	8.73e-39	142.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQW5@28211|Alphaproteobacteria,3EYHU@335928|Xanthobacteraceae	28211|Alphaproteobacteria	G	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k59_539527_1	56780.SYN_02361	1.83e-46	167.0	COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,1MV37@1224|Proteobacteria,42N4N@68525|delta/epsilon subdivisions,2WKJ1@28221|Deltaproteobacteria,2MRBJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HD,HD_5
k59_1770380_1	709032.Sulku_0097	4.61e-54	171.0	COG2010@1|root,COG2010@2|Bacteria,1NKKK@1224|Proteobacteria,42UAC@68525|delta/epsilon subdivisions,2YRSI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
k59_10451_1	159087.Daro_0265	1.94e-52	184.0	COG0642@1|root,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,2VIXT@28216|Betaproteobacteria,2KUH6@206389|Rhodocyclales	206389|Rhodocyclales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2222,HAMP,HATPase_c,HisKA,Response_reg,dCache_1
k59_831936_1	326298.Suden_0933	2.89e-23	98.6	COG1233@1|root,COG1233@2|Bacteria,1P0N4@1224|Proteobacteria,42NRZ@68525|delta/epsilon subdivisions,2YMGH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8
k59_831936_2	1537917.JU82_08085	1.6e-124	367.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,42R4U@68525|delta/epsilon subdivisions,2YNY0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
k59_949664_1	1537917.JU82_01670	6.67e-97	312.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,43DMZ@68525|delta/epsilon subdivisions,2YMMS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_1594442_1	159087.Daro_0282	1.1e-13	69.7	COG0116@1|root,COG0116@2|Bacteria,1MUQM@1224|Proteobacteria,2VHMY@28216|Betaproteobacteria,2KV05@206389|Rhodocyclales	206389|Rhodocyclales	L	Belongs to the methyltransferase superfamily	-	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
k59_1594442_2	159087.Daro_0281	6.71e-67	206.0	COG1981@1|root,COG1981@2|Bacteria,1RHGS@1224|Proteobacteria,2VR5Y@28216|Betaproteobacteria,2KWBC@206389|Rhodocyclales	206389|Rhodocyclales	S	membrane	-	-	-	ko:K08973	-	-	-	-	ko00000	-	-	-	UPF0093
k59_1594442_3	1304883.KI912532_gene513	2.3e-87	265.0	COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria,2VJ3T@28216|Betaproteobacteria,2KUSE@206389|Rhodocyclales	206389|Rhodocyclales	GM	epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
k59_1537063_1	709032.Sulku_0292	5.45e-71	228.0	COG4773@1|root,COG4773@2|Bacteria,1QZMX@1224|Proteobacteria,42SA0@68525|delta/epsilon subdivisions,2YPCD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1770396_2	709032.Sulku_2314	1.41e-110	318.0	COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,42R5N@68525|delta/epsilon subdivisions,2YNX0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petA	-	1.10.2.2	ko:K00411	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,UCR_Fe-S_N
k59_66914_2	1249480.B649_01725	1.85e-88	273.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,42NGE@68525|delta/epsilon subdivisions,2YN37@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0471 Di- and tricarboxylate	-	-	-	ko:K03319	-	-	-	-	ko00000	2.A.47	-	-	Na_sulph_symp
k59_127715_1	202955.BBND01000015_gene1634	2.82e-56	177.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,1S3QK@1236|Gammaproteobacteria,3NN8W@468|Moraxellaceae	1236|Gammaproteobacteria	J	Ribosomal protein L17	rplQ	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
k59_127715_2	317025.Tcr_0319	1.54e-54	180.0	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,1RMU3@1236|Gammaproteobacteria,4603Q@72273|Thiotrichales	72273|Thiotrichales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
k59_831983_1	1537917.JU82_03795	5.33e-86	280.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2YMJS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,NIT,Response_reg
k59_244239_1	159087.Daro_3826	1.32e-120	354.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,2VH7E@28216|Betaproteobacteria,2KUEM@206389|Rhodocyclales	206389|Rhodocyclales	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
k59_420064_1	1165841.SULAR_04157	3.36e-51	172.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,42MIA@68525|delta/epsilon subdivisions,2YMH1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_420064_2	387093.SUN_0651	2.33e-99	305.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,42M2G@68525|delta/epsilon subdivisions,2YMS0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
k59_1419067_1	159087.Daro_3836	3.33e-107	330.0	COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,2VH5H@28216|Betaproteobacteria,2KV5J@206389|Rhodocyclales	206389|Rhodocyclales	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
k59_1830813_1	709032.Sulku_1821	3.09e-91	271.0	2ENFG@1|root,33G2V@2|Bacteria,1NPDC@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
k59_1358825_1	1165841.SULAR_00340	2.37e-100	301.0	COG0754@1|root,COG0754@2|Bacteria,1MW6V@1224|Proteobacteria,42N3V@68525|delta/epsilon subdivisions,2YMBJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Glutathionylspermidine synthase	gss	-	-	-	-	-	-	-	-	-	-	-	GSP_synth
k59_127736_1	1249480.B649_06535	4.8e-124	365.0	COG2710@1|root,COG2710@2|Bacteria,1MVY2@1224|Proteobacteria,42MMI@68525|delta/epsilon subdivisions,2YNPZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Nitrogenase protein alpha chain	-	-	1.18.6.1	ko:K02586	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_nitro
k59_184400_1	387093.SUN_1075	4.57e-72	226.0	COG2220@1|root,COG2220@2|Bacteria,1MV20@1224|Proteobacteria,42QPP@68525|delta/epsilon subdivisions,2YP9R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
k59_771405_1	1165841.SULAR_09104	5.76e-141	417.0	COG2199@1|root,COG2203@1|root,COG2204@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,COG2204@2|Bacteria,1RGKE@1224|Proteobacteria,43CM2@68525|delta/epsilon subdivisions,2YTK3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_9,Response_reg
k59_890037_1	62928.azo3017	2.93e-86	267.0	COG3203@1|root,COG3203@2|Bacteria,1MWUN@1224|Proteobacteria,2VN8D@28216|Betaproteobacteria,2KUJ1@206389|Rhodocyclales	206389|Rhodocyclales	M	Outer membrane protein (Porin)	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
k59_301588_1	338969.Rfer_3638	4.07e-94	281.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,2VH1F@28216|Betaproteobacteria,4AC8G@80864|Comamonadaceae	28216|Betaproteobacteria	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD_5
k59_1594522_1	388051.AUFE01000006_gene1192	2.9e-67	219.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,2VIGJ@28216|Betaproteobacteria,1K30M@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PFAM HI0933 family protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
k59_420108_1	1280668.ATVT01000002_gene2888	1.01e-06	53.9	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TQCS@1239|Firmicutes,248SC@186801|Clostridia,4BYWA@830|Butyrivibrio	186801|Clostridia	T	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
k59_10537_1	87626.PTD2_08704	1.78e-09	60.1	COG1017@1|root,COG1017@2|Bacteria,1QUQ4@1224|Proteobacteria,1SAA1@1236|Gammaproteobacteria,2Q3DW@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	C	Globin	-	-	1.14.12.17	ko:K05916	ko05132,map05132	-	-	-	ko00000,ko00001,ko01000	-	-	-	Globin
k59_10537_2	1537917.JU82_03635	3.28e-68	210.0	COG3448@1|root,COG3448@2|Bacteria,1MXJG@1224|Proteobacteria,42RSQ@68525|delta/epsilon subdivisions,2YRW7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	HPP family	-	-	-	-	-	-	-	-	-	-	-	-	HPP
k59_301607_1	1249480.B649_06405	3.11e-43	153.0	COG3014@1|root,COG3014@2|Bacteria	2|Bacteria	S	protein conserved in bacteria	-	-	-	ko:K09859	-	-	-	-	ko00000	-	-	-	-
k59_301607_2	1537917.JU82_06205	4.32e-38	130.0	2AMIU@1|root,31CEJ@2|Bacteria,1Q8IS@1224|Proteobacteria,433MF@68525|delta/epsilon subdivisions,2YSR7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF1425)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1425
k59_1419146_1	159087.Daro_0773	4.49e-75	243.0	COG1766@1|root,COG1766@2|Bacteria,1MUQR@1224|Proteobacteria,2VI9M@28216|Betaproteobacteria,2KVMR@206389|Rhodocyclales	206389|Rhodocyclales	N	The M ring may be actively involved in energy transduction	fliF	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
k59_1834459_2	159087.Daro_0718	3.24e-86	258.0	COG3198@1|root,COG3198@2|Bacteria,1N75J@1224|Proteobacteria,2VTYE@28216|Betaproteobacteria,2KX1A@206389|Rhodocyclales	206389|Rhodocyclales	S	FixH family	-	-	-	ko:K09926	-	-	-	-	ko00000	-	-	-	FixH
k59_1656116_1	1353529.M899_1194	6.21e-28	120.0	COG0642@1|root,COG0642@2|Bacteria,1NXDJ@1224|Proteobacteria,43BMJ@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GAF,HATPase_c,HisKA,Hpt,MASE1,PAS_3,PAS_4,PAS_9,Response_reg
k59_1247553_1	765912.Thimo_1243	2.19e-14	77.8	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,1RQ8B@1236|Gammaproteobacteria,1WXE6@135613|Chromatiales	135613|Chromatiales	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,PAS_8
k59_1069501_1	349124.Hhal_2255	1.67e-08	60.8	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,1WWYN@135613|Chromatiales	135613|Chromatiales	U	type IV pilus secretin PilQ	-	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
k59_1773374_1	1537917.JU82_04575	1.44e-60	187.0	COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,42SGM@68525|delta/epsilon subdivisions,2YPJ3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
k59_1773374_2	1150621.SMUL_0675	7.62e-17	73.6	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,42THK@68525|delta/epsilon subdivisions,2YQ0A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
k59_952989_1	1249480.B649_08865	3.94e-148	437.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,42M6W@68525|delta/epsilon subdivisions,2YN2C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	spoT	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT,HD_4,RelA_SpoT,TGS
k59_600036_1	1454004.AW11_03467	2.03e-13	68.6	COG0745@1|root,COG0745@2|Bacteria,1Q2S0@1224|Proteobacteria,2VM6W@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Pfam Response regulator receiver	rstA	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_600036_2	159087.Daro_3145	7.11e-52	167.0	COG1495@1|root,COG1495@2|Bacteria,1RIJE@1224|Proteobacteria,2VREE@28216|Betaproteobacteria,2KWY0@206389|Rhodocyclales	206389|Rhodocyclales	C	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein	dsbB	-	-	ko:K03611	-	-	-	-	ko00000,ko03110	5.A.2.1	-	-	DsbB
k59_1834513_1	159087.Daro_1120	3.07e-103	308.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,2VI7D@28216|Betaproteobacteria,2KUTE@206389|Rhodocyclales	206389|Rhodocyclales	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_1302697_1	491952.Mar181_3039	1.12e-17	79.7	COG0461@1|root,COG0461@2|Bacteria,1MW6F@1224|Proteobacteria,1RQYG@1236|Gammaproteobacteria,1XHYH@135619|Oceanospirillales	135619|Oceanospirillales	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
k59_1302697_2	159087.Daro_0121	1.04e-59	190.0	28NWD@1|root,2ZBU8@2|Bacteria,1RGNH@1224|Proteobacteria,2VRUN@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124
k59_1834517_1	679197.HMPREF9336_02799	1.12e-14	74.7	COG1975@1|root,COG1975@2|Bacteria	2|Bacteria	O	molybdopterin cofactor binding	xdhC	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
k59_1834517_2	469381.Dpep_1827	7.41e-31	127.0	COG4630@1|root,COG4630@2|Bacteria,3TAMB@508458|Synergistetes	508458|Synergistetes	C	CO dehydrogenase flavoprotein	-	-	1.17.1.4,1.2.5.3	ko:K03518,ko:K13481	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2
k59_1834517_3	1297863.APJF01000009_gene216	1.98e-08	53.9	COG2080@1|root,COG2080@2|Bacteria,1RJC4@1224|Proteobacteria,2VEWT@28211|Alphaproteobacteria,3JXZE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
k59_69364_1	1249480.B649_05960	1.74e-96	286.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,42MMS@68525|delta/epsilon subdivisions,2YMA2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	hydrolase, TatD	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
k59_69364_2	1249480.B649_05955	3.08e-192	543.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,42M5C@68525|delta/epsilon subdivisions,2YM7M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	lytic murein transglycosylase	mltD	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
k59_1012613_1	709032.Sulku_1011	2.24e-140	410.0	COG0668@1|root,COG0668@2|Bacteria,1PMY3@1224|Proteobacteria,42M4K@68525|delta/epsilon subdivisions,2YMAQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
k59_1129576_1	1123393.KB891317_gene2475	3.42e-93	281.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,1N2YQ@1224|Proteobacteria,2VIAK@28216|Betaproteobacteria,1KRUJ@119069|Hydrogenophilales	119069|Hydrogenophilales	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DNA_binding_1
k59_247445_1	1165841.SULAR_05538	2.29e-100	296.0	COG0745@1|root,COG0745@2|Bacteria,1Q5DC@1224|Proteobacteria,42R42@68525|delta/epsilon subdivisions,2YNXG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_1597415_1	709032.Sulku_1674	6.2e-73	223.0	COG2062@1|root,COG2062@2|Bacteria,1N0FX@1224|Proteobacteria,42TJ0@68525|delta/epsilon subdivisions,2YPZ4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	phosphohistidine phosphatase, SixA	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
k59_1597415_2	709032.Sulku_1445	1.21e-29	108.0	COG2346@1|root,COG2346@2|Bacteria,1Q196@1224|Proteobacteria,42T3P@68525|delta/epsilon subdivisions,2YPP7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COGs COG2346 Truncated hemoglobins	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
k59_1069557_1	1158146.KB907134_gene1480	1.6e-53	182.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,1RMC3@1236|Gammaproteobacteria,1WWKP@135613|Chromatiales	135613|Chromatiales	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	-	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
k59_1069557_2	243159.AFE_3285	3.23e-39	142.0	COG0247@1|root,COG1145@1|root,COG0247@2|Bacteria,COG1145@2|Bacteria,1MUMH@1224|Proteobacteria,1RNBY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Fe-S oxidoreductase	dgcB	-	-	ko:K21834	-	-	-	-	ko00000	-	-	-	CCG,DUF3483,Fer4_8
k59_131305_1	1454004.AW11_03576	3.76e-85	265.0	COG0454@1|root,COG0456@2|Bacteria,1R8GF@1224|Proteobacteria,2VNUV@28216|Betaproteobacteria	28216|Betaproteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,PilZ
k59_1834548_1	1537917.JU82_07640	1.84e-203	571.0	COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,42M78@68525|delta/epsilon subdivisions,2YMR1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
k59_1834548_2	1249480.B649_03880	8.81e-09	55.5	COG4733@1|root,COG4733@2|Bacteria,1N010@1224|Proteobacteria,42M7U@68525|delta/epsilon subdivisions,2YM7Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Fibronectin type 3 domain-containing protein	-	-	-	ko:K06882	-	-	-	-	ko00000	-	-	-	fn3
k59_1656194_1	555778.Hneap_1702	2.34e-70	224.0	COG0697@1|root,COG0697@2|Bacteria,1MWSU@1224|Proteobacteria,1RSF8@1236|Gammaproteobacteria,1WZCT@135613|Chromatiales	135613|Chromatiales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_1773419_2	1537917.JU82_05595	2.14e-133	384.0	COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,42N54@68525|delta/epsilon subdivisions,2YNS5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
k59_1773419_3	1537917.JU82_05590	8.83e-45	149.0	2BEW6@1|root,328MU@2|Bacteria,1QAUA@1224|Proteobacteria,42VY6@68525|delta/epsilon subdivisions,2YQED@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1540885_1	1304883.KI912532_gene2058	8.18e-35	128.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,2VIEM@28216|Betaproteobacteria,2KVIM@206389|Rhodocyclales	206389|Rhodocyclales	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	odhB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
k59_1540885_2	159087.Daro_2859	1.66e-52	183.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,2VJ0G@28216|Betaproteobacteria,2KVN8@206389|Rhodocyclales	206389|Rhodocyclales	C	Dehydrogenase E1 component	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
k59_660580_1	159087.Daro_3354	4.6e-85	270.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1MUQV@1224|Proteobacteria,2VJ24@28216|Betaproteobacteria,2KZNZ@206389|Rhodocyclales	206389|Rhodocyclales	T	LapD/MoxY periplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,LapD_MoxY_N
k59_543420_1	95619.PM1_0200495	1.89e-27	112.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RM7S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	COG0739 Membrane proteins related to metalloendopeptidases	yebA	-	-	-	-	-	-	-	-	-	-	-	OapA,OapA_N,Peptidase_M23
k59_1422932_1	1122599.AUGR01000016_gene2821	4.66e-87	270.0	COG0077@1|root,COG0077@2|Bacteria,1MU60@1224|Proteobacteria,1RNRD@1236|Gammaproteobacteria,1XISZ@135619|Oceanospirillales	135619|Oceanospirillales	E	Prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
k59_1422932_2	713586.KB900536_gene477	1.61e-54	181.0	COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,1RMKU@1236|Gammaproteobacteria,1WWHV@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
k59_1540889_1	1123392.AQWL01000005_gene3004	2.39e-123	365.0	COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,2VIJH@28216|Betaproteobacteria,1KSRT@119069|Hydrogenophilales	119069|Hydrogenophilales	P	NMT1-like family	-	-	-	-	-	-	-	-	-	-	-	-	NMT1_2
k59_1247680_1	1537917.JU82_10810	1.05e-91	280.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,42NGG@68525|delta/epsilon subdivisions,2YN35@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Nucleotidyltransferase DNA polymerase involved in DNA repair	dinP	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
k59_543431_2	580332.Slit_0853	5.96e-38	127.0	2E1ZQ@1|root,32X83@2|Bacteria,1N4MV@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_543431_3	857087.Metme_2859	8.15e-07	48.1	COG3209@1|root,COG3209@2|Bacteria,1N7AI@1224|Proteobacteria,1SDRH@1236|Gammaproteobacteria,1XFTS@135618|Methylococcales	135618|Methylococcales	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_600106_1	717605.Theco_1901	1.41e-62	196.0	COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,4HFRA@91061|Bacilli,26RCN@186822|Paenibacillaceae	91061|Bacilli	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS08940	DMRL_synthase
k59_600106_2	1123517.JOMR01000001_gene911	1.2e-06	50.8	COG0781@1|root,COG0781@2|Bacteria,1RHFZ@1224|Proteobacteria,1S6AJ@1236|Gammaproteobacteria,4616R@72273|Thiotrichales	72273|Thiotrichales	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
k59_1540908_1	387093.SUN_2220	6.26e-121	362.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2YN0B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
k59_1834601_1	338969.Rfer_2881	3.26e-94	295.0	COG5492@1|root,COG5492@2|Bacteria,1QY8X@1224|Proteobacteria,2VJ6A@28216|Betaproteobacteria	28216|Betaproteobacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1540914_1	709032.Sulku_1890	2.49e-91	290.0	COG0457@1|root,COG4783@1|root,COG0457@2|Bacteria,COG4783@2|Bacteria,1QV15@1224|Proteobacteria,42NKI@68525|delta/epsilon subdivisions,2YMKG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	COG0457 FOG TPR repeat	pflB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_6,TPR_8
k59_1247709_2	1249480.B649_10505	2e-96	285.0	COG4784@1|root,COG4784@2|Bacteria,1QX39@1224|Proteobacteria,43DAM@68525|delta/epsilon subdivisions,2YTHR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
k59_835411_1	382245.ASA_2109	5.72e-21	97.1	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG2202@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1Y3V7@135624|Aeromonadales	135624|Aeromonadales	T	Hpt domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,HATPase_c,HisKA,Hpt,PAS_3,Response_reg
k59_1834618_1	159087.Daro_0104	7.45e-203	575.0	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,2VH50@28216|Betaproteobacteria,2KV59@206389|Rhodocyclales	206389|Rhodocyclales	I	poly(R)-hydroxyalkanoic acid synthase	-	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,PhaC_N
k59_702463_1	666681.M301_1313	4.06e-102	302.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,2VHSG@28216|Betaproteobacteria,2KM9T@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
k59_1634315_1	177439.DP2788	1.67e-109	328.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,42MUZ@68525|delta/epsilon subdivisions,2WJT6@28221|Deltaproteobacteria,2MHUV@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_1105870_1	159087.Daro_0033	1.69e-123	370.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,2VINT@28216|Betaproteobacteria,2KVAV@206389|Rhodocyclales	206389|Rhodocyclales	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C
k59_1105872_1	1461577.CCMH01000018_gene378	1.31e-05	47.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,1HWNM@117743|Flavobacteriia	976|Bacteroidetes	S	ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_1105872_2	709032.Sulku_0427	3.17e-73	226.0	COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,42PJB@68525|delta/epsilon subdivisions,2YNGQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k59_1398331_1	1165841.SULAR_00050	3.3e-73	220.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,42SEH@68525|delta/epsilon subdivisions,2YPE2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	FG	Hit family	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
k59_639284_1	709032.Sulku_2542	1.98e-120	365.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2YN94@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
k59_1515393_1	159087.Daro_0030	4.31e-14	70.9	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,2VIDI@28216|Betaproteobacteria,2KV2P@206389|Rhodocyclales	206389|Rhodocyclales	T	Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k59_1515393_2	159087.Daro_0029	2.06e-104	305.0	29CX4@1|root,2ZZV8@2|Bacteria,1RFY7@1224|Proteobacteria,2VR98@28216|Betaproteobacteria,2KWGK@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of unknown function (DUF4390)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4390
k59_1464124_2	312309.VF_2017	2.53e-27	105.0	2CPEB@1|root,32SIW@2|Bacteria,1MZE0@1224|Proteobacteria,1SARU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1515395_1	1249480.B649_05265	1.92e-35	128.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,42N7U@68525|delta/epsilon subdivisions,2YN72@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	PFAM Radical SAM domain protein	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Radical_SAM
k59_1515395_2	709032.Sulku_1280	1.73e-90	265.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2YPJX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
k59_1634348_1	709032.Sulku_0662	9.34e-13	66.6	COG2199@1|root,COG3706@2|Bacteria,1MVCZ@1224|Proteobacteria,43AWN@68525|delta/epsilon subdivisions,2YT3U@29547|Epsilonproteobacteria	1224|Proteobacteria	T	TIGRFAM diguanylate cyclase (GGDEF) domain	dosC	GO:0003674,GO:0003824,GO:0005488,GO:0008144,GO:0016740,GO:0016772,GO:0016779,GO:0019825,GO:0020037,GO:0036094,GO:0042165,GO:0043167,GO:0043169,GO:0046906,GO:0048037,GO:0052621,GO:0070025,GO:0097159,GO:1901363	2.7.7.65	ko:K13069,ko:K13590,ko:K18967	ko04112,map04112	-	R08057	-	ko00000,ko00001,ko01000,ko02000	9.B.34.1.1	-	-	GGDEF,Protoglobin
k59_1169880_1	1249480.B649_10395	1.07e-22	95.1	COG1578@1|root,COG1578@2|Bacteria,1RI11@1224|Proteobacteria,42RA1@68525|delta/epsilon subdivisions,2YNYT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function DUF89	-	-	-	ko:K09116	-	-	-	-	ko00000	-	-	-	DUF89
k59_994263_1	290633.GOX1926	7.58e-19	89.7	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2TQRZ@28211|Alphaproteobacteria,2JPRN@204441|Rhodospirillales	204441|Rhodospirillales	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
k59_994263_2	887062.HGR_06386	2.48e-53	175.0	COG3310@1|root,COG3310@2|Bacteria,1RDE0@1224|Proteobacteria,2VQ9D@28216|Betaproteobacteria,4AA25@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1415)	-	-	-	ko:K09941	-	-	-	-	ko00000	-	-	-	DUF1415
k59_1173196_1	1150621.SMUL_3235	1.03e-29	120.0	COG0790@1|root,COG2829@1|root,COG0790@2|Bacteria,COG2829@2|Bacteria,1PC8I@1224|Proteobacteria,42R3P@68525|delta/epsilon subdivisions,2YPBM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COGs COG2829 Outer membrane phospholipase A	-	-	3.1.1.32,3.1.1.4	ko:K01058	ko00564,ko00565,ko00590,ko00591,ko00592,ko01100,ko01110,map00564,map00565,map00590,map00591,map00592,map01100,map01110	-	R01315,R01316,R01317,R02053,R02054,R04034,R07064,R07379,R07387,R07859,R07860	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko01000	-	-	-	PLA1
k59_1108778_1	1217652.F954_02867	8.98e-47	165.0	COG1783@1|root,COG1783@2|Bacteria,1R66A@1224|Proteobacteria,1RQFD@1236|Gammaproteobacteria,3NSTS@468|Moraxellaceae	1236|Gammaproteobacteria	S	Phage terminase large subunit	-	-	-	ko:K06909	-	-	-	-	ko00000	-	-	-	Terminase_3,Terminase_3C
k59_642166_1	159087.Daro_0726	6.94e-40	150.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VI5B@28216|Betaproteobacteria,2KVAE@206389|Rhodocyclales	206389|Rhodocyclales	NT	Signal transducing histidine kinase, homodimeric domain	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
k59_1290969_1	1357400.HMPREF2086_01749	1.33e-13	78.2	COG0642@1|root,COG0642@2|Bacteria,1QUJA@1224|Proteobacteria,42MZ2@68525|delta/epsilon subdivisions,2YN1R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_1290973_1	1537917.JU82_06380	1.6e-106	317.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,42PCH@68525|delta/epsilon subdivisions,2YN62@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	3-deoxy-d-manno-octulosonic-acid transferase	kdtA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	iIT341.HP0957	Glycos_transf_N
k59_1341062_1	944547.ABLL_0539	2.66e-28	116.0	COG2010@1|root,COG2010@2|Bacteria,1NG71@1224|Proteobacteria,42P5C@68525|delta/epsilon subdivisions,2YNRE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_817704_1	76114.ebA1714	2.67e-53	172.0	2AP99@1|root,31EB9@2|Bacteria,1RM04@1224|Proteobacteria,2W2S7@28216|Betaproteobacteria,2KYW1@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1173239_1	1121035.AUCH01000013_gene3129	3.45e-50	167.0	2B96M@1|root,322HU@2|Bacteria,1RIIU@1224|Proteobacteria,2VT7Z@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	FecR
k59_1173239_2	159087.Daro_1152	1.19e-74	229.0	COG0426@1|root,COG0426@2|Bacteria,1N2Y0@1224|Proteobacteria,2VH72@28216|Betaproteobacteria,2KVXH@206389|Rhodocyclales	206389|Rhodocyclales	C	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_172312_1	1172190.M947_00885	5.24e-28	107.0	2AJ5D@1|root,319PZ@2|Bacteria,1Q3HS@1224|Proteobacteria,42XCD@68525|delta/epsilon subdivisions,2YQQ3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Chemotaxis phosphatase CheX	-	-	-	-	-	-	-	-	-	-	-	-	CheX
k59_103207_1	1165841.SULAR_10364	5.24e-113	360.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2YMP9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5,RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_47018_1	1094980.Mpsy_1040	3.13e-34	136.0	COG2202@1|root,COG3221@1|root,arCOG01805@2157|Archaea,arCOG06515@2157|Archaea,2Y3GY@28890|Euryarchaeota,2NASN@224756|Methanomicrobia	224756|Methanomicrobia	PT	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,Phosphonate-bd
k59_1693950_1	1300005.R9RG79_9CAUD	8.85e-102	310.0	4QEFX@10239|Viruses,4QYYG@35237|dsDNA viruses  no RNA stage,4QRRV@28883|Caudovirales,4QNTK@10744|Podoviridae	10744|Podoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_870492_1	1537917.JU82_06710	3.98e-79	244.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,42R7E@68525|delta/epsilon subdivisions,2YNXU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Omptin
k59_935050_1	1249480.B649_07705	1.1e-190	538.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,42M7Y@68525|delta/epsilon subdivisions,2YMTB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	argininosuccinate lyase	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
k59_1108858_1	90814.KL370891_gene129	9.57e-106	332.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,1RNZ2@1236|Gammaproteobacteria,4608B@72273|Thiotrichales	72273|Thiotrichales	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
k59_642252_1	331678.Cphamn1_2441	1.94e-48	161.0	COG2062@1|root,COG2062@2|Bacteria,1FE6K@1090|Chlorobi	1090|Chlorobi	T	PFAM Phosphoglycerate mutase	-	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
k59_1518684_1	373903.Hore_03740	4.24e-16	76.6	COG1309@1|root,COG2355@1|root,COG1309@2|Bacteria,COG2355@2|Bacteria,1V8M2@1239|Firmicutes,24J7T@186801|Clostridia	186801|Clostridia	K	tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_1518684_2	1230342.CTM_21978	7.06e-33	119.0	COG2227@1|root,COG2227@2|Bacteria,1VSM2@1239|Firmicutes,24G5E@186801|Clostridia,36R90@31979|Clostridiaceae	186801|Clostridia	H	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
k59_1877504_1	204669.Acid345_2841	7.24e-122	355.0	COG2089@1|root,COG2089@2|Bacteria,3Y39R@57723|Acidobacteria,2JM50@204432|Acidobacteriia	204432|Acidobacteriia	M	NeuB family	-	-	2.5.1.56	ko:K01654	ko00520,ko01100,map00520,map01100	-	R01804,R04435	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB
k59_1637613_1	929558.SMGD1_2679	1.28e-87	276.0	COG0726@1|root,COG1649@1|root,COG0726@2|Bacteria,COG1649@2|Bacteria,1MWR2@1224|Proteobacteria,43AG1@68525|delta/epsilon subdivisions,2YT1V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Hypothetical glycosyl hydrolase family 13	-	-	-	ko:K11931	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000	-	-	-	GHL13,Polysacc_deac_1
k59_1291045_1	159087.Daro_3658	1.14e-120	357.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,2VHHS@28216|Betaproteobacteria,2KU74@206389|Rhodocyclales	206389|Rhodocyclales	O	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3,SurA_N
k59_103259_1	1537917.JU82_03710	1.73e-79	247.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,42NF0@68525|delta/epsilon subdivisions,2YMRR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3
k59_1291056_1	557598.LHK_02083	4.35e-67	211.0	COG0348@1|root,COG0348@2|Bacteria,1MWR5@1224|Proteobacteria,2VJYI@28216|Betaproteobacteria	28216|Betaproteobacteria	C	TIGRFAM ferredoxin-type protein, NapH MauN family	napH	-	-	ko:K02574	-	-	-	-	ko00000	-	-	-	Fer4_10,Fer4_5,Fer4_6,Fer4_7,Fer4_9
k59_1877518_1	159087.Daro_2025	1.44e-37	127.0	COG0526@1|root,COG0526@2|Bacteria,1QVC9@1224|Proteobacteria,2VYGG@28216|Betaproteobacteria,2KXAK@206389|Rhodocyclales	206389|Rhodocyclales	CO	COG0526 Thiol-disulfide isomerase and thioredoxins	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	DUF836
k59_1877518_2	580332.Slit_1279	1.36e-60	201.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,2VHM5@28216|Betaproteobacteria,44V33@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
k59_746017_1	709032.Sulku_1387	1.33e-65	216.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,42PUI@68525|delta/epsilon subdivisions,2YN3E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	PFAM TrkA-N domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2,TrkA_N
k59_746017_2	314345.SPV1_05844	4.89e-29	117.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria	1224|Proteobacteria	L	Atp-dependent helicase	hrpB	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
k59_1518718_1	640081.Dsui_3442	1.4e-103	310.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,2VKI2@28216|Betaproteobacteria,2KX65@206389|Rhodocyclales	206389|Rhodocyclales	S	FAD-dependent pyridine nucleotide-disulfide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_1694028_1	1249480.B649_09215	1.11e-108	318.0	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,42QRC@68525|delta/epsilon subdivisions,2YNZB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
k59_1466879_1	709032.Sulku_1368	6.33e-58	183.0	2A00Z@1|root,30N34@2|Bacteria,1Q52P@1224|Proteobacteria,430EH@68525|delta/epsilon subdivisions,2YS0F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1877573_1	159087.Daro_0356	2.59e-177	512.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,2VHE8@28216|Betaproteobacteria,2KUCJ@206389|Rhodocyclales	206389|Rhodocyclales	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
k59_1108957_1	709032.Sulku_2029	1.11e-75	226.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42UQ6@68525|delta/epsilon subdivisions,2YQ4Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	PFAM PAS fold-3 domain protein	-	-	-	ko:K03776	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	PAS_3
k59_1108957_2	1537917.JU82_08440	2.25e-55	187.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,42M4S@68525|delta/epsilon subdivisions,2YM8Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	-	-	1.12.5.1	ko:K05922	-	-	-	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
k59_1877601_1	104623.Ser39006_03231	4.51e-20	91.7	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,1RMQU@1236|Gammaproteobacteria,400F4@613|Serratia	1236|Gammaproteobacteria	H	Is involved in the formation of active molybdenum cofactor and the chelation of molybdenum	moeA	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0042802,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	iEcHS_1320.EcHS_A0885	MoCF_biosynth,MoeA_C,MoeA_N
k59_1694082_1	522306.CAP2UW1_2602	3.19e-23	105.0	COG2202@1|root,COG2703@1|root,COG3437@1|root,COG4251@1|root,COG2202@2|Bacteria,COG2703@2|Bacteria,COG3437@2|Bacteria,COG4251@2|Bacteria,1NWNJ@1224|Proteobacteria,2WHVM@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Pfam Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	PAS,Response_reg
k59_1291144_1	1537917.JU82_10865	3.65e-206	583.0	COG0464@1|root,COG0464@2|Bacteria,1N4ZI@1224|Proteobacteria,42NGJ@68525|delta/epsilon subdivisions,2YMAX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	ATPase (AAA	-	-	-	-	-	-	-	-	-	-	-	-	AAA
k59_47155_2	159087.Daro_0105	1.93e-23	94.7	COG1977@1|root,COG1977@2|Bacteria,1PT86@1224|Proteobacteria,2VYZI@28216|Betaproteobacteria,2KZFC@206389|Rhodocyclales	206389|Rhodocyclales	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_997282_1	1121035.AUCH01000015_gene2492	2.11e-11	70.5	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VI5B@28216|Betaproteobacteria,2KVQE@206389|Rhodocyclales	206389|Rhodocyclales	T	chemotaxis protein	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
k59_997286_1	1249480.B649_05085	4.54e-248	706.0	COG1344@1|root,COG1344@2|Bacteria,1N1QF@1224|Proteobacteria,42PDD@68525|delta/epsilon subdivisions,2YMYD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	flgL	-	-	ko:K02397	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
k59_400379_1	709032.Sulku_0613	1.91e-22	100.0	2AJ4C@1|root,319NV@2|Bacteria,1Q3D8@1224|Proteobacteria,431S6@68525|delta/epsilon subdivisions,2YS5U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_400379_2	1249480.B649_03060	8.82e-79	235.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,42N4Z@68525|delta/epsilon subdivisions,2YTJ1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07305,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
k59_47173_1	159087.Daro_0413	8.09e-113	330.0	COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,2VHEU@28216|Betaproteobacteria,2KUZN@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
k59_400388_1	1249480.B649_05910	8.54e-158	458.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,42M1S@68525|delta/epsilon subdivisions,2YMEF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	penicillin-binding protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
k59_997302_1	317025.Tcr_0289	1.62e-182	548.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,45ZP4@72273|Thiotrichales	72273|Thiotrichales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_460928_1	159087.Daro_1948	1.05e-76	231.0	COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,2VRGK@28216|Betaproteobacteria,2KWEM@206389|Rhodocyclales	206389|Rhodocyclales	K	Transcriptional regulator	iscR	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
k59_1224566_1	1249480.B649_00720	1.16e-53	184.0	COG1345@1|root,COG1345@2|Bacteria,1MUVP@1224|Proteobacteria,42MHW@68525|delta/epsilon subdivisions,2YNJG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	fliD	GO:0001539,GO:0005575,GO:0005576,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_IN,FliD_C,FliD_N
k59_172582_2	709032.Sulku_1155	8.61e-31	114.0	COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,42QWE@68525|delta/epsilon subdivisions,2YNG3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	ABC transporter, periplasmic molybdate-binding protein	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
k59_47218_1	1323663.AROI01000063_gene3851	7.69e-53	183.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,1RMXX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	GO:0000270,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0006869,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010876,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0030203,GO:0031224,GO:0031226,GO:0033036,GO:0034203,GO:0034204,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0055085,GO:0061024,GO:0065007,GO:0065008,GO:0070589,GO:0071554,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0097035,GO:1901135,GO:1901137,GO:1901264,GO:1901505,GO:1901564,GO:1901566,GO:1901576	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	iECO103_1326.ECO103_1114	MVIN
k59_1877691_1	316278.SynRCC307_1648	4.47e-12	66.6	COG0001@1|root,COG0001@2|Bacteria,1G162@1117|Cyanobacteria,1GYKV@1129|Synechococcus	1117|Cyanobacteria	H	Glutamate-1-semialdehyde aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_1877691_2	387093.SUN_1246	6.03e-35	122.0	COG5336@1|root,COG5336@2|Bacteria,1NHIS@1224|Proteobacteria,42VGZ@68525|delta/epsilon subdivisions,2YQ8C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
k59_1877691_3	1165841.SULAR_03148	0.000964	41.6	2AIU4@1|root,319B6@2|Bacteria,1Q28N@1224|Proteobacteria,42V6E@68525|delta/epsilon subdivisions,2YQ6D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1467003_1	709032.Sulku_0387	1.23e-90	276.0	29W5U@1|root,30HQY@2|Bacteria,1QUJN@1224|Proteobacteria,42NUV@68525|delta/epsilon subdivisions,2YNFP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_870750_1	159087.Daro_1325	9.5e-63	202.0	COG1418@1|root,COG1418@2|Bacteria,1QWG6@1224|Proteobacteria,2WGYR@28216|Betaproteobacteria,2KYWM@206389|Rhodocyclales	206389|Rhodocyclales	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
k59_870750_2	159087.Daro_1324	5.88e-28	110.0	COG0582@1|root,COG0582@2|Bacteria,1MVZB@1224|Proteobacteria,2VN1J@28216|Betaproteobacteria,2KWR3@206389|Rhodocyclales	206389|Rhodocyclales	L	Pfam:DUF3596	-	-	-	ko:K14059	-	-	-	-	ko00000	-	-	-	Arm-DNA-bind_2,Phage_int_SAM_3,Phage_integrase
k59_172640_1	709032.Sulku_2615	1.07e-81	252.0	COG2319@1|root,COG2319@2|Bacteria,1QYMQ@1224|Proteobacteria,43E8Q@68525|delta/epsilon subdivisions,2YTBF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_746214_1	983917.RGE_03270	5.74e-103	307.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,2VH5D@28216|Betaproteobacteria,1KJXX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
k59_461021_1	1121935.AQXX01000137_gene3924	1.08e-15	77.8	COG2836@1|root,COG2836@2|Bacteria,1RIGJ@1224|Proteobacteria,1S5V1@1236|Gammaproteobacteria,1XJ7Q@135619|Oceanospirillales	135619|Oceanospirillales	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
k59_461021_2	87626.PTD2_09848	1.16e-29	120.0	COG2992@1|root,COG2992@2|Bacteria,1RD3U@1224|Proteobacteria,1S3RA@1236|Gammaproteobacteria,2Q2X0@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	-	-	-	ko:K03796	-	-	-	-	ko00000	-	GH73	-	Glucosaminidase
k59_818015_2	159087.Daro_1097	1.5e-26	105.0	COG2141@1|root,COG2141@2|Bacteria,1MVF0@1224|Proteobacteria,2VHXM@28216|Betaproteobacteria,2KUN5@206389|Rhodocyclales	206389|Rhodocyclales	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
k59_818024_2	351348.Maqu_0788	3.46e-88	268.0	COG0451@1|root,COG0451@2|Bacteria,1MVE4@1224|Proteobacteria,1RP2S@1236|Gammaproteobacteria,469RJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	F	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose	hldD	GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008712,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016853,GO:0016854,GO:0016857,GO:0033692,GO:0034637,GO:0034645,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0048037,GO:0050661,GO:0050662,GO:0070401,GO:0071704,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901576,GO:1903509	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iPC815.YPO0058,iYL1228.KPN_03963	Epimerase
k59_523484_2	633697.EubceDRAFT1_0883	2.3e-08	52.8	COG4495@1|root,COG4495@2|Bacteria,1VHEX@1239|Firmicutes,24RC9@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4176)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4176
k59_1877804_1	522772.Dacet_0669	4.71e-17	75.5	COG2963@1|root,COG2963@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
k59_1291354_1	1249480.B649_06590	4.91e-93	283.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MSP@68525|delta/epsilon subdivisions,2YNBC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.14	ko:K02594	ko00620,map00620	-	R00271	RC00004,RC00067,RC02754	ko00000,ko00001,ko01000	-	-	-	HMGL-like
k59_103493_1	2340.JV46_24230	3.38e-50	181.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,MHYT,PAS_3,PAS_4,PAS_9
k59_1291359_1	159087.Daro_1795	4.11e-63	198.0	29AFQ@1|root,2ZXFW@2|Bacteria,1RGFB@1224|Proteobacteria,2VQD0@28216|Betaproteobacteria,2KYP8@206389|Rhodocyclales	206389|Rhodocyclales	S	Transcription factor zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-TFIIB
k59_1291359_2	1304883.KI912532_gene2235	4.76e-38	133.0	COG0500@1|root,COG2226@2|Bacteria,1RKQD@1224|Proteobacteria,2VQJ7@28216|Betaproteobacteria,2KUBG@206389|Rhodocyclales	206389|Rhodocyclales	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k59_746274_1	1249480.B649_09435	2.13e-171	500.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42Z31@68525|delta/epsilon subdivisions,2YRAR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Hpt sensor hybrid histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
k59_1291366_1	159087.Daro_0872	2.07e-103	305.0	COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,2VHEQ@28216|Betaproteobacteria,2KUCF@206389|Rhodocyclales	206389|Rhodocyclales	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
k59_642626_1	709032.Sulku_0350	7.6e-113	336.0	COG0628@1|root,COG0628@2|Bacteria,1PMAR@1224|Proteobacteria,42TGZ@68525|delta/epsilon subdivisions,2YR9I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k59_1401372_1	159087.Daro_0861	2.63e-135	394.0	COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,2VHSH@28216|Betaproteobacteria,2KVD8@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
k59_935517_2	709032.Sulku_0054	1.21e-85	268.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,42M3S@68525|delta/epsilon subdivisions,2YN4P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	GTP-binding protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
k59_362810_1	1537917.JU82_00635	7.47e-103	306.0	COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,42NI1@68525|delta/epsilon subdivisions,2YMHQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
k59_1246581_1	1304883.KI912532_gene2679	8.08e-44	160.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,2KV7D@206389|Rhodocyclales	206389|Rhodocyclales	NT	Cache_2	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,dCache_2,sCache_2
k59_68617_1	2340.JV46_28720	3.7e-94	284.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,1RMHP@1236|Gammaproteobacteria,1J536@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006928,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0010212,GO:0031668,GO:0033554,GO:0034641,GO:0040011,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048870,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
k59_1539802_1	709032.Sulku_0784	2.02e-119	343.0	COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,42SI3@68525|delta/epsilon subdivisions,2YRUU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Membrane	-	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
k59_1246596_1	159087.Daro_2186	3.29e-64	204.0	COG2885@1|root,COG2885@2|Bacteria,1MWHF@1224|Proteobacteria,2VIJS@28216|Betaproteobacteria,2KYGK@206389|Rhodocyclales	206389|Rhodocyclales	M	OmpA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA
k59_1246596_2	159087.Daro_2187	2.34e-47	161.0	COG3913@1|root,COG3913@2|Bacteria,1P1K2@1224|Proteobacteria,2VI4H@28216|Betaproteobacteria,2KXIJ@206389|Rhodocyclales	206389|Rhodocyclales	S	Uncharacterized protein conserved in bacteria (DUF2094)	-	-	-	ko:K11890	ko02025,map02025	-	-	-	ko00000,ko00001,ko02044	-	-	-	DUF2094
k59_130341_1	1132855.KB913035_gene332	2.72e-61	208.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KNHH@206350|Nitrosomonadales	206350|Nitrosomonadales	T	MASE1	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,MASE1,PAS,PAS_9
k59_422143_2	1095769.CAHF01000011_gene2136	7.97e-08	56.6	COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,2VJB8@28216|Betaproteobacteria,472SD@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	TamB, inner membrane protein subunit of TAM complex	tamB	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
k59_1361120_1	1163617.SCD_n01087	6.98e-19	89.7	COG0501@1|root,COG0501@2|Bacteria,1NXSW@1224|Proteobacteria,2W3ME@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
k59_542341_1	1537917.JU82_05785	8e-50	172.0	COG3203@1|root,COG3203@2|Bacteria,1QVBP@1224|Proteobacteria,42M72@68525|delta/epsilon subdivisions,2YNNX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	outer membrane porin, OprD family	-	-	-	-	-	-	-	-	-	-	-	-	OprD
k59_186602_1	709032.Sulku_0330	8.19e-97	294.0	COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,42KZP@68525|delta/epsilon subdivisions,2YMBP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG1055 Na H antiporter NhaD and related arsenite	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
k59_246563_1	1249480.B649_03190	3.11e-35	132.0	COG1143@1|root,COG2768@1|root,COG1143@2|Bacteria,COG2768@2|Bacteria,1N7HT@1224|Proteobacteria	1224|Proteobacteria	C	4fe-4s ferredoxin, iron-sulfur binding	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
k59_952181_1	709032.Sulku_0087	2.06e-32	119.0	COG0810@1|root,COG0810@2|Bacteria,1R7A2@1224|Proteobacteria	1224|Proteobacteria	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
k59_952181_2	1537917.JU82_03005	6.63e-40	137.0	2BSDP@1|root,32MFN@2|Bacteria,1Q399@1224|Proteobacteria,42Y0H@68525|delta/epsilon subdivisions,2YQR2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_952181_3	709032.Sulku_0014	1.94e-148	435.0	COG3203@1|root,COG3203@2|Bacteria,1QZ2N@1224|Proteobacteria,42QVI@68525|delta/epsilon subdivisions,2YP28@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_130370_1	1485544.JQKP01000010_gene792	3.67e-43	160.0	COG2199@1|root,COG2202@1|root,COG2199@2|Bacteria,COG2202@2|Bacteria,1NWNJ@1224|Proteobacteria,2WHIC@28216|Betaproteobacteria,44WDC@713636|Nitrosomonadales	28216|Betaproteobacteria	T	SMART GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,sCache_3_2
k59_1479845_1	159087.Daro_0916	1.42e-18	80.9	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2VQ3Z@28216|Betaproteobacteria,2KW7U@206389|Rhodocyclales	206389|Rhodocyclales	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	-	5.2.1.8	ko:K01802,ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
k59_1479845_2	159087.Daro_0915	7.39e-102	295.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2VQ3Z@28216|Betaproteobacteria,2KW4W@206389|Rhodocyclales	206389|Rhodocyclales	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
k59_1421877_1	1121456.ATVA01000011_gene1674	6.75e-16	78.2	COG2897@1|root,COG2897@2|Bacteria,1RKQN@1224|Proteobacteria,42SKC@68525|delta/epsilon subdivisions,2WPW7@28221|Deltaproteobacteria,2MBKC@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,YceI
k59_1421877_2	367737.Abu_0458	5.03e-18	79.3	COG2010@1|root,COG2010@2|Bacteria,1NKKK@1224|Proteobacteria,42UAC@68525|delta/epsilon subdivisions,2YQ26@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
k59_246577_3	1356852.N008_03920	5.17e-44	149.0	COG0224@1|root,COG0224@2|Bacteria,4PKME@976|Bacteroidetes,47XWH@768503|Cytophagia	976|Bacteroidetes	C	WbqC-like protein family	-	-	-	-	-	-	-	-	-	-	-	-	WbqC
k59_1713923_1	709032.Sulku_1186	6.49e-89	283.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,42N4X@68525|delta/epsilon subdivisions,2YMTD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Belongs to the FtsK SpoIIIE SftA family	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
k59_1655433_2	398578.Daci_2842	1.24e-24	94.0	COG3530@1|root,COG3530@2|Bacteria,1N7GT@1224|Proteobacteria,2VW2G@28216|Betaproteobacteria,4AFFU@80864|Comamonadaceae	28216|Betaproteobacteria	S	Putative quorum-sensing-regulated virulence factor	-	-	-	ko:K09954	-	-	-	-	ko00000	-	-	-	QSregVF_b
k59_1246671_2	709032.Sulku_0463	5.1e-12	65.1	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,42NBS@68525|delta/epsilon subdivisions,2YMPP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	riboflavin biosynthesis protein	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
k59_1833604_1	1215092.PA6_006_01590	0.000499	42.7	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1YF4V@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	2.7.7.65	ko:K21023	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	EAL,GGDEF,MHYT,PAS_9
k59_1833604_2	1123366.TH3_10966	8.83e-51	182.0	COG1283@1|root,COG1283@2|Bacteria,1MUDE@1224|Proteobacteria,2TRF9@28211|Alphaproteobacteria,2JQEV@204441|Rhodospirillales	204441|Rhodospirillales	P	Na+/Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
k59_1068787_1	159087.Daro_0336	3.63e-69	213.0	COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,2VQ80@28216|Betaproteobacteria,2KVMQ@206389|Rhodocyclales	206389|Rhodocyclales	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
k59_1068787_2	1304883.KI912532_gene460	2.18e-06	46.6	COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,2VSH0@28216|Betaproteobacteria,2KWNI@206389|Rhodocyclales	206389|Rhodocyclales	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
k59_362911_2	709032.Sulku_2514	1.56e-303	837.0	COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,42MYF@68525|delta/epsilon subdivisions,2YMXD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Single-stranded-DNA-specific exonuclease (RecJ)	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
k59_362911_3	1249480.B649_09480	1.14e-81	256.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,42NYV@68525|delta/epsilon subdivisions,2YN1D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	pyridine nucleotide-disulfide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_542449_1	709032.Sulku_2269	0.0	1032.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2YMP9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5,RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_1772659_1	977880.RALTA_A0538	1.44e-63	220.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,1K044@119060|Burkholderiaceae	28216|Betaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	mdtC	-	-	ko:K03296,ko:K07788,ko:K07789	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	2.A.6.2	-	-	ACR_tran
k59_1655467_1	1537917.JU82_04135	3.34e-42	144.0	COG4106@1|root,COG4106@2|Bacteria,1QZ2S@1224|Proteobacteria,43CEU@68525|delta/epsilon subdivisions,2YTCB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Methyltransferase domain	-	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
k59_834569_1	1403948.Q618_VCMC00001G0061	0.000134	43.1	2DX7X@1|root,32V2Y@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_246655_2	1121935.AQXX01000129_gene1754	2.75e-44	155.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,1RP6E@1236|Gammaproteobacteria,1XH4I@135619|Oceanospirillales	135619|Oceanospirillales	L	TatD family	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
k59_1539992_1	709032.Sulku_0513	8.33e-76	241.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,42M14@68525|delta/epsilon subdivisions,2YMWB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Biotin carboxylase	pycA	-	6.3.4.14,6.4.1.1,6.4.1.2	ko:K01959,ko:K01961	ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko01230,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212,map01230	M00082,M00173,M00376,M00620	R00344,R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
k59_1068835_2	709032.Sulku_1518	8.16e-44	144.0	COG1669@1|root,COG1669@2|Bacteria,1NA7M@1224|Proteobacteria,42V5F@68525|delta/epsilon subdivisions,2YQAC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM DNA polymerase beta domain protein region	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
k59_1185714_1	28229.ND2E_4079	9.95e-100	305.0	COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,1RMMT@1236|Gammaproteobacteria,2Q6I6@267889|Colwelliaceae	1236|Gammaproteobacteria	M	Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate	mpl	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0016874,GO:0016879,GO:0016881,GO:0042802,GO:0044424,GO:0044464	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	iSDY_1059.SDY_4251	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_1185714_2	90813.JQMT01000001_gene1615	7.4e-14	72.8	COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,1RPBP@1236|Gammaproteobacteria,4600Z@72273|Thiotrichales	72273|Thiotrichales	J	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
k59_1714039_2	1449345.JHWC01000006_gene971	2.25e-46	163.0	COG0175@1|root,COG0175@2|Bacteria,1PDGI@1224|Proteobacteria,42XXI@68525|delta/epsilon subdivisions	1224|Proteobacteria	EH	Phosphoadenosine phosphosulfate reductase family	-	-	-	-	-	-	-	-	-	-	-	-	PAPS_reduct
k59_485224_1	2340.JV46_10780	1.01e-85	258.0	COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,1RQDN@1236|Gammaproteobacteria,1J4WI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Part of a membrane complex involved in electron transport	rnfA	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
k59_485224_2	391615.ABSJ01000022_gene292	5.12e-60	192.0	COG2878@1|root,COG2878@2|Bacteria,1MUWU@1224|Proteobacteria,1RNSJ@1236|Gammaproteobacteria,1J5SD@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Part of a membrane complex involved in electron transport	rnfB	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4_21
k59_1836118_1	159087.Daro_4152	2.87e-122	355.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,2VHNA@28216|Betaproteobacteria,2KUUY@206389|Rhodocyclales	206389|Rhodocyclales	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
k59_305584_1	1249480.B649_07270	1.16e-27	109.0	COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,42P4E@68525|delta/epsilon subdivisions,2YNAC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs	truD	-	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
k59_305584_2	1165841.SULAR_03482	4.93e-62	199.0	COG3021@1|root,COG3021@2|Bacteria,1MVPP@1224|Proteobacteria,42TM7@68525|delta/epsilon subdivisions,2YQ62@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
k59_715035_1	1537917.JU82_11510	2.37e-128	369.0	COG1189@1|root,COG1189@2|Bacteria,1MWP5@1224|Proteobacteria,42R2J@68525|delta/epsilon subdivisions,2YNYE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Hemolysin	tlyA	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
k59_1774718_1	709032.Sulku_1076	4.98e-55	181.0	COG3228@1|root,COG3228@2|Bacteria,1RAHF@1224|Proteobacteria,42QKQ@68525|delta/epsilon subdivisions,2YMYQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the MtfA family	-	-	-	ko:K09933	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_M90
k59_1131193_1	1121035.AUCH01000007_gene468	6.81e-93	276.0	COG3258@1|root,COG3258@2|Bacteria,1MXB0@1224|Proteobacteria,2VJ8Q@28216|Betaproteobacteria,2KY5E@206389|Rhodocyclales	206389|Rhodocyclales	C	Thiosulfate-oxidizing multienzyme system protein SoxA	-	-	-	ko:K17222	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	-
k59_248869_1	709032.Sulku_0004	4.81e-101	307.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1RGCV@1224|Proteobacteria,42M47@68525|delta/epsilon subdivisions,2YMRS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	(EAL) domain protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_132913_1	709032.Sulku_1031	3.37e-35	130.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,42Q9B@68525|delta/epsilon subdivisions,2YNKN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.2.3	ko:K17229	ko00920,ko01120,map00920,map01120	-	R09499	-	ko00000,ko00001,ko01000	-	-	-	FCSD-flav_bind,Pyr_redox_2,TAT_signal
k59_132913_2	1537917.JU82_10600	3.24e-87	261.0	COG0723@1|root,COG0723@2|Bacteria,1MZ7A@1224|Proteobacteria,42N9F@68525|delta/epsilon subdivisions,2YNBZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
k59_1716025_1	935837.JAEK01000012_gene375	1.01e-20	89.7	COG1284@1|root,COG1284@2|Bacteria,1TQTP@1239|Firmicutes,4HBV2@91061|Bacilli,1ZCF3@1386|Bacillus	91061|Bacilli	S	Uncharacterized protein conserved in bacteria (DUF2179)	yqfU	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
k59_1716025_2	1403313.AXBR01000021_gene3256	1.46e-21	94.0	COG2171@1|root,COG2171@2|Bacteria,1TQUJ@1239|Firmicutes,4H9KY@91061|Bacilli,1ZBFG@1386|Bacillus	91061|Bacilli	E	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate	dapH	-	2.3.1.117,2.3.1.89	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	M00016,M00525	R04364,R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU14180	DapH_N,Hexapep
k59_305627_1	118005.AWNK01000003_gene2333	3.6e-52	177.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	pglA	GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.4.1.290,2.4.1.52	ko:K00712,ko:K15914	-	-	R10188	RC00005,RC00049	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_2,Glycos_transf_1
k59_188644_1	159087.Daro_3789	8.92e-141	401.0	COG0346@1|root,COG0346@2|Bacteria,1MUWY@1224|Proteobacteria,2VKV3@28216|Betaproteobacteria,2KUG0@206389|Rhodocyclales	206389|Rhodocyclales	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	1.13.11.2	ko:K00446	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
k59_424277_1	709032.Sulku_2657	5.22e-32	124.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42MX5@68525|delta/epsilon subdivisions,2YMSQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)	-	-	2.7.7.13,5.4.2.8	ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II
k59_424277_2	1165841.SULAR_03777	1.65e-61	207.0	COG1449@1|root,COG1449@2|Bacteria,1P2YJ@1224|Proteobacteria,42N8E@68525|delta/epsilon subdivisions,2YNF0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
k59_1774760_1	1537917.JU82_05800	6.2e-48	167.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,42NAX@68525|delta/epsilon subdivisions,2YN4X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
k59_1774760_2	709032.Sulku_1829	1.36e-48	160.0	COG0847@1|root,COG0847@2|Bacteria,1P0GY@1224|Proteobacteria,42RBT@68525|delta/epsilon subdivisions,2YNWW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	dna polymerase iii	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_1836192_1	1172190.M947_05325	1.56e-135	417.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,42NHZ@68525|delta/epsilon subdivisions,2YMTE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	5-methyltetrahydrofolate--homocysteine methyltransferase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
k59_132943_1	387093.SUN_0278	1.26e-92	282.0	COG2223@1|root,COG2223@2|Bacteria,1QVWW@1224|Proteobacteria,43CKR@68525|delta/epsilon subdivisions,2YN1B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_14240_1	519989.ECTPHS_06972	3.34e-74	241.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,1RMDD@1236|Gammaproteobacteria,1WVW2@135613|Chromatiales	135613|Chromatiales	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
k59_894445_1	1123487.KB892846_gene626	1.58e-82	270.0	COG3511@1|root,COG3511@2|Bacteria,1MVNS@1224|Proteobacteria,2VMDC@28216|Betaproteobacteria	28216|Betaproteobacteria	M	PFAM Phosphoesterase	acpA	-	-	-	-	-	-	-	-	-	-	-	Phosphoesterase
k59_485326_1	1537917.JU82_10045	3.45e-110	330.0	2DCNX@1|root,2ZESX@2|Bacteria,1QUV9@1224|Proteobacteria,43CMN@68525|delta/epsilon subdivisions,2YTEI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1249379_1	1537917.JU82_04510	2.12e-21	89.4	COG0607@1|root,COG4802@1|root,COG0607@2|Bacteria,COG4802@2|Bacteria,1QYD3@1224|Proteobacteria,42PN1@68525|delta/epsilon subdivisions,2YMYE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CP	PFAM Ferredoxin thioredoxin reductase catalytic beta chain	-	-	-	-	-	-	-	-	-	-	-	-	FeThRed_B,Rhodanese
k59_1249379_2	709032.Sulku_0729	1.52e-59	186.0	COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,42SCQ@68525|delta/epsilon subdivisions,2YPEP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
k59_954577_1	1537917.JU82_06840	3.48e-126	380.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,42MM9@68525|delta/epsilon subdivisions,2YMH2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
k59_1774808_1	1178482.BJB45_18740	3.56e-105	314.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,1RMEC@1236|Gammaproteobacteria,1XHA8@135619|Oceanospirillales	135619|Oceanospirillales	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
k59_1071131_1	1249480.B649_02285	5.26e-62	192.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,42THF@68525|delta/epsilon subdivisions,2YPXJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
k59_1071131_2	709032.Sulku_0463	1.73e-101	303.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,42NBS@68525|delta/epsilon subdivisions,2YMPP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	riboflavin biosynthesis protein	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
k59_1363537_1	398767.Glov_1988	3.47e-42	152.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2WIK8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_9
k59_248948_1	1249480.B649_09770	7.36e-141	404.0	COG2899@1|root,COG2899@2|Bacteria,1NURT@1224|Proteobacteria,42MRA@68525|delta/epsilon subdivisions,2YNAM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF475)	-	-	-	ko:K09799	-	-	-	-	ko00000	-	-	-	DUF475
k59_1249394_1	1249480.B649_04740	3.46e-109	323.0	29CAW@1|root,2ZZ9C@2|Bacteria,1Q5FH@1224|Proteobacteria,42Q2S@68525|delta/epsilon subdivisions,2YP18@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_424330_1	159087.Daro_0725	2.67e-74	223.0	COG0745@1|root,COG0745@2|Bacteria,1RHDD@1224|Proteobacteria,2VSDT@28216|Betaproteobacteria,2KWAN@206389|Rhodocyclales	206389|Rhodocyclales	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
k59_424330_2	159087.Daro_0723	4.33e-31	117.0	COG1360@1|root,COG1360@2|Bacteria,1MW1Y@1224|Proteobacteria,2VHMJ@28216|Betaproteobacteria,2KV8A@206389|Rhodocyclales	206389|Rhodocyclales	N	flagellar motor protein	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
k59_1249414_1	159087.Daro_2897	2.18e-145	418.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,2VH25@28216|Betaproteobacteria,2KUQ7@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF	-	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_1790606_2	709032.Sulku_2192	2.06e-57	184.0	COG1387@1|root,COG1387@2|Bacteria,1RCEG@1224|Proteobacteria,42MIM@68525|delta/epsilon subdivisions,2YMFF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	histidinol phosphate phosphatase	hisJ	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP,PHP_C
k59_852245_1	321327.CYA_2863	3.23e-18	87.8	COG3001@1|root,COG3001@2|Bacteria,1G040@1117|Cyanobacteria,1GZY8@1129|Synechococcus	1117|Cyanobacteria	G	COG3001 Fructosamine-3-kinase	-	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
k59_1790615_1	1304883.KI912532_gene1719	4.26e-68	210.0	COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,2VJVJ@28216|Betaproteobacteria,2KV35@206389|Rhodocyclales	206389|Rhodocyclales	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
k59_1790615_2	159087.Daro_0807	1.3e-26	99.4	COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,2VSJ2@28216|Betaproteobacteria,2KWKM@206389|Rhodocyclales	206389|Rhodocyclales	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
k59_852257_1	583345.Mmol_0701	4.92e-81	248.0	COG0501@1|root,COG0501@2|Bacteria,1MUNA@1224|Proteobacteria,2VHTB@28216|Betaproteobacteria,2KKPW@206350|Nitrosomonadales	206350|Nitrosomonadales	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
k59_1497212_1	1537917.JU82_07845	1.89e-77	257.0	COG0755@1|root,COG1333@1|root,COG0755@2|Bacteria,COG1333@2|Bacteria,1RG0A@1224|Proteobacteria,42N37@68525|delta/epsilon subdivisions,2YMXW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Cytochrome c biogenesis protein	ccsBA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
k59_1673932_1	572480.Arnit_2441	4.09e-13	76.3	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42NFR@68525|delta/epsilon subdivisions,2YMNU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_3,PAS_9
k59_1614817_2	945713.IALB_2344	1.87e-22	98.6	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K01420,ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
k59_440433_1	159087.Daro_3829	8.49e-98	294.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,2VHW3@28216|Betaproteobacteria,2KV52@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K18901	-	M00698	-	-	ko00000,ko00002,ko01504,ko02000	2.A.6.2,8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_1790648_1	1249480.B649_01445	4.94e-115	362.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2YMJS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,NIT,Response_reg
k59_1088303_2	666681.M301_0060	2.93e-47	156.0	COG0526@1|root,COG0526@2|Bacteria,1MZ5J@1224|Proteobacteria,2VU93@28216|Betaproteobacteria,2KMY4@206350|Nitrosomonadales	206350|Nitrosomonadales	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
k59_1203653_2	709032.Sulku_0987	1.84e-55	182.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,42M8G@68525|delta/epsilon subdivisions,2YME5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
k59_566154_1	1121035.AUCH01000002_gene1415	2.21e-82	270.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,2KV6Z@206389|Rhodocyclales	206389|Rhodocyclales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_620873_1	1537917.JU82_11545	2.26e-39	138.0	COG1193@1|root,COG1193@2|Bacteria,1QUJI@1224|Proteobacteria,42P7P@68525|delta/epsilon subdivisions,2YMFB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	GO:0000018,GO:0008150,GO:0009892,GO:0010605,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0080090	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
k59_1673990_1	864069.MicloDRAFT_00005550	2.7e-53	177.0	COG3415@1|root,COG3415@2|Bacteria,1QWT2@1224|Proteobacteria,2TX4K@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Rhodopirellula transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013
k59_1203684_1	1249480.B649_01515	3.47e-104	322.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,42N34@68525|delta/epsilon subdivisions,2YMFS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_C
k59_1856663_1	159087.Daro_1423	8.78e-06	46.6	COG0666@1|root,COG0666@2|Bacteria,1QVCE@1224|Proteobacteria,2VUWR@28216|Betaproteobacteria,2KYZ2@206389|Rhodocyclales	206389|Rhodocyclales	P	Ankyrin repeats (many copies)	-	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	-
k59_151121_1	1165841.SULAR_08909	5.11e-76	251.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,42MWW@68525|delta/epsilon subdivisions,2YMMH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_973558_1	395493.BegalDRAFT_0638	5.07e-76	254.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,1RMYD@1236|Gammaproteobacteria,4600V@72273|Thiotrichales	72273|Thiotrichales	E	Vitamin B12 dependent methionine synthase, activation	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
k59_1037385_1	90813.JQMT01000001_gene260	3.03e-92	281.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,1RNDK@1236|Gammaproteobacteria,45ZSV@72273|Thiotrichales	72273|Thiotrichales	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
k59_1856682_1	438753.AZC_3575	1.87e-106	324.0	COG5410@1|root,COG5410@2|Bacteria,1N0W2@1224|Proteobacteria,2U18J@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6C
k59_379528_1	1385519.N801_02755	3.16e-14	78.2	COG1020@1|root,COG1020@2|Bacteria,2GKGU@201174|Actinobacteria,4FIKH@85021|Intrasporangiaceae	201174|Actinobacteria	I	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
k59_1563194_1	983545.Glaag_0601	1.93e-114	344.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,1RN0R@1236|Gammaproteobacteria,4640T@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	actP	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
k59_1563194_2	517418.Ctha_1887	1.26e-07	49.3	COG4327@1|root,COG4327@2|Bacteria,1FE5F@1090|Chlorobi	1090|Chlorobi	S	Domain of unknown function (DUF4212)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4212
k59_1270214_1	709032.Sulku_0450	1.35e-128	380.0	COG4773@1|root,COG4773@2|Bacteria,1QZ1U@1224|Proteobacteria,42PHE@68525|delta/epsilon subdivisions,2YN5J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Receptor	-	-	-	-	-	-	-	-	-	-	-	-	OprD
k59_151210_1	1165841.SULAR_04182	6.09e-52	168.0	COG3439@1|root,COG3439@2|Bacteria,1MZ38@1224|Proteobacteria,42V9F@68525|delta/epsilon subdivisions,2YQRK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
k59_1380708_2	266265.Bxe_A0168	3.17e-15	72.4	COG1516@1|root,COG1516@2|Bacteria,1MZ3G@1224|Proteobacteria,2VU2S@28216|Betaproteobacteria,1K72X@119060|Burkholderiaceae	28216|Betaproteobacteria	N	flagellar protein FliS	fliS	-	-	ko:K02422	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliS
k59_1497353_1	159087.Daro_3290	3.53e-19	83.2	COG3437@1|root,COG3437@2|Bacteria,1RJ22@1224|Proteobacteria,2VSV3@28216|Betaproteobacteria	28216|Betaproteobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
k59_1497353_2	1392838.AWNM01000036_gene785	1.02e-05	47.8	COG0625@1|root,COG0625@2|Bacteria,1RHSK@1224|Proteobacteria,2VPTJ@28216|Betaproteobacteria,3T5FQ@506|Alcaligenaceae	28216|Betaproteobacteria	O	Glutathione S-transferase, C-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_N_3
k59_1037470_2	709032.Sulku_0481	1.25e-36	131.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,42P56@68525|delta/epsilon subdivisions,2YNV5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
k59_1037476_1	387093.SUN_1515	1.47e-20	95.5	COG1216@1|root,COG1216@2|Bacteria,1N5RX@1224|Proteobacteria,42SF0@68525|delta/epsilon subdivisions,2YRNI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
k59_318359_1	709032.Sulku_1992	6.31e-57	177.0	COG3370@1|root,COG3370@2|Bacteria,1N27G@1224|Proteobacteria,42UAJ@68525|delta/epsilon subdivisions,2YPZ8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM DsrE DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
k59_318359_2	709032.Sulku_1993	1.31e-77	234.0	COG0748@1|root,COG0748@2|Bacteria,1REH2@1224|Proteobacteria,42WSK@68525|delta/epsilon subdivisions,2YQ8W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07226	-	-	-	-	ko00000	-	-	-	DUF2470,Putative_PNPOx
k59_1203786_1	702450.CUW_0823	2.1e-81	255.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,3VNTC@526524|Erysipelotrichia	526524|Erysipelotrichia	H	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
k59_1445860_1	1537917.JU82_10045	1.57e-69	225.0	2DCNX@1|root,2ZESX@2|Bacteria,1QUV9@1224|Proteobacteria,43CMN@68525|delta/epsilon subdivisions,2YTEI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1615020_1	877455.Metbo_0911	3.5e-14	79.7	COG0463@1|root,arCOG01381@2157|Archaea,2XX4Q@28890|Euryarchaeota,23NZN@183925|Methanobacteria	183925|Methanobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_151265_1	709032.Sulku_0082	6.76e-104	304.0	COG2836@1|root,COG2836@2|Bacteria,1RIGJ@1224|Proteobacteria,42Q44@68525|delta/epsilon subdivisions,2YNTJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
k59_1270280_2	1121035.AUCH01000008_gene961	2.31e-64	208.0	COG2141@1|root,COG2141@2|Bacteria,1MVF0@1224|Proteobacteria,2VHXM@28216|Betaproteobacteria,2KUN5@206389|Rhodocyclales	206389|Rhodocyclales	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
k59_795648_1	1454004.AW11_02710	2.36e-39	149.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,2VJCZ@28216|Betaproteobacteria,1KQ5X@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	O	peptidylprolyl isomerase	ppiD	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
k59_1790831_1	1537917.JU82_08485	8.22e-166	488.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,42M70@68525|delta/epsilon subdivisions,2YMJM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_566355_1	1249480.B649_07400	3.99e-95	290.0	COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,42MCZ@68525|delta/epsilon subdivisions,2YNV4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	HlyD membrane-fusion protein of T1SS	-	-	-	ko:K12542	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	3.A.1.109.4,8.A.1	-	-	HlyD_3
k59_1380792_1	1165841.SULAR_01878	1.58e-67	216.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,42MIA@68525|delta/epsilon subdivisions,2YMH1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_1380792_2	1150621.SMUL_2430	5.91e-19	81.6	COG4276@1|root,COG4276@2|Bacteria	2|Bacteria	-	-	sulA	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase,Polyketide_cyc,Polyketide_cyc2
k59_1674153_1	159087.Daro_0637	7.35e-64	202.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,2VI08@28216|Betaproteobacteria,2KVU7@206389|Rhodocyclales	206389|Rhodocyclales	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
k59_1674153_2	159087.Daro_0638	6.15e-74	233.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,2VHPE@28216|Betaproteobacteria,2KUZY@206389|Rhodocyclales	206389|Rhodocyclales	U	type II secretion system protein	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
k59_1037581_1	159087.Daro_3869	6.09e-161	462.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,2VJ07@28216|Betaproteobacteria,2KVNA@206389|Rhodocyclales	206389|Rhodocyclales	H	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis	ubiB	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
k59_1445941_1	1249480.B649_06430	5.71e-82	248.0	COG0745@1|root,COG0745@2|Bacteria,1PFGE@1224|Proteobacteria,42U08@68525|delta/epsilon subdivisions,2YPVW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_504159_1	159087.Daro_3202	1.99e-101	314.0	COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,2VP2B@28216|Betaproteobacteria,2KV4S@206389|Rhodocyclales	206389|Rhodocyclales	V	COG2274 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	-	-	-	ko:K12541	ko02010,map02010	M00330	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.109.3,3.A.1.109.4	-	-	ABC_membrane,ABC_tran
k59_795733_1	159087.Daro_3859	2.47e-88	265.0	COG3245@1|root,COG3245@2|Bacteria,1MZBZ@1224|Proteobacteria,2VMBB@28216|Betaproteobacteria,2KWMI@206389|Rhodocyclales	206389|Rhodocyclales	C	cytochrome c5	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
k59_1445992_1	1165841.SULAR_01035	6.43e-73	245.0	COG0465@1|root,COG0465@2|Bacteria,1NQVB@1224|Proteobacteria,42MWB@68525|delta/epsilon subdivisions,2YR9A@29547|Epsilonproteobacteria	2|Bacteria	O	Peptidase family M41	-	-	-	-	-	-	-	-	-	-	-	-	AAA,Peptidase_M41
k59_795739_1	56780.SYN_02270	3.66e-23	97.1	COG0530@1|root,COG0530@2|Bacteria	2|Bacteria	P	calcium, potassium:sodium antiporter activity	yrbG	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
k59_795739_2	666681.M301_1814	5.44e-33	119.0	COG1846@1|root,COG1846@2|Bacteria,1PW9W@1224|Proteobacteria,2VUDE@28216|Betaproteobacteria,2KNYR@206350|Nitrosomonadales	206350|Nitrosomonadales	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR
k59_27577_1	159087.Daro_1880	5.09e-28	104.0	COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,2VSN0@28216|Betaproteobacteria,2KWPR@206389|Rhodocyclales	206389|Rhodocyclales	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
k59_27577_2	640081.Dsui_2053	1.04e-61	191.0	COG1403@1|root,COG1403@2|Bacteria,1RGZQ@1224|Proteobacteria,2VSZE@28216|Betaproteobacteria,2KWRE@206389|Rhodocyclales	206389|Rhodocyclales	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH
k59_727481_2	709032.Sulku_2189	1.39e-52	167.0	COG1433@1|root,COG1433@2|Bacteria,1P8Y4@1224|Proteobacteria,42VVM@68525|delta/epsilon subdivisions,2YQI1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1856941_1	1249480.B649_07715	4.53e-151	441.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,42MGF@68525|delta/epsilon subdivisions,2YN0E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the UbiD family	menA	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0396	UbiD
k59_973792_1	749222.Nitsa_1418	9.9e-08	53.1	COG0438@1|root,COG0438@2|Bacteria,1N9EV@1224|Proteobacteria,42PK2@68525|delta/epsilon subdivisions,2YNE2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_973792_2	547144.HydHO_1546	8.92e-89	270.0	COG0438@1|root,COG0438@2|Bacteria,2G4PW@200783|Aquificae	200783|Aquificae	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_1446034_1	640081.Dsui_3327	3.7e-39	138.0	COG3658@1|root,COG3658@2|Bacteria,1RIG7@1224|Proteobacteria,2VQQ0@28216|Betaproteobacteria,2KW85@206389|Rhodocyclales	206389|Rhodocyclales	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
k59_1446034_2	697282.Mettu_0214	1.42e-12	69.3	COG0457@1|root,COG0457@2|Bacteria,1REPB@1224|Proteobacteria,1SA23@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19
k59_621128_1	90814.KL370891_gene714	2.91e-89	281.0	COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,1RMSM@1236|Gammaproteobacteria,4604H@72273|Thiotrichales	72273|Thiotrichales	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
k59_1380917_1	1249480.B649_09830	2.74e-97	306.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,42KZ9@68525|delta/epsilon subdivisions,2YMS4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_1270450_1	1537917.JU82_08640	2.32e-90	266.0	2AHPN@1|root,3181V@2|Bacteria,1PZNU@1224|Proteobacteria,42QWU@68525|delta/epsilon subdivisions,2YMYS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF3972)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3972
k59_1270450_2	709032.Sulku_2197	7.71e-29	110.0	COG1578@1|root,COG1578@2|Bacteria,1RI11@1224|Proteobacteria,42RA1@68525|delta/epsilon subdivisions,2YNYT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function DUF89	-	-	-	ko:K09116	-	-	-	-	ko00000	-	-	-	DUF89
k59_1204004_1	583345.Mmol_0043	1.95e-91	287.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VPI0@28216|Betaproteobacteria,2KMGA@206350|Nitrosomonadales	206350|Nitrosomonadales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_910608_1	1165841.SULAR_05828	6.9e-136	411.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,42MKB@68525|delta/epsilon subdivisions,2YMIZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
k59_1563494_1	312153.Pnuc_1175	2.66e-46	164.0	COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria	2|Bacteria	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HD,HD_5,PAS_4,PAS_9,PocR
k59_854902_3	1484157.PSNIH2_05140	1.15e-09	60.8	COG3562@1|root,COG3562@2|Bacteria,1NB0M@1224|Proteobacteria,1SG8X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Capsule polysaccharide biosynthesis protein	-	-	-	ko:K07265	-	-	-	-	ko00000	-	-	-	Capsule_synth
k59_443276_1	1537917.JU82_06755	8.31e-68	206.0	COG0858@1|root,COG0858@2|Bacteria,1Q48R@1224|Proteobacteria,42UQE@68525|delta/epsilon subdivisions,2YPZY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
k59_686516_1	1454004.AW11_01418	4.35e-108	320.0	COG0252@1|root,COG0252@2|Bacteria,1MWIR@1224|Proteobacteria,2VJI2@28216|Betaproteobacteria,1KR00@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	EJ	Asparaginase	ansA	-	3.5.1.1,3.5.1.38	ko:K01424,ko:K05597	ko00220,ko00250,ko00460,ko00471,ko01100,ko01110,ko02020,map00220,map00250,map00460,map00471,map01100,map01110,map02020	-	R00256,R00485,R01579	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
k59_1041121_1	1122599.AUGR01000011_gene4122	3.33e-20	95.1	COG3023@1|root,COG3420@1|root,COG3023@2|Bacteria,COG3420@2|Bacteria,1NGRY@1224|Proteobacteria,1T22S@1236|Gammaproteobacteria,1XS0U@135619|Oceanospirillales	135619|Oceanospirillales	P	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
k59_267571_1	387093.SUN_2042	4.88e-88	271.0	COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,42N08@68525|delta/epsilon subdivisions,2YMRG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	folylpolyglutamate synthase	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
k59_29639_1	1123507.ATVQ01000001_gene963	0.000458	42.0	COG1024@1|root,COG1024@2|Bacteria,2GJW5@201174|Actinobacteria,1W859@1268|Micrococcaceae	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	echA8	GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0030312,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
k59_1566634_1	523791.Kkor_0288	0.000362	43.5	COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,1RPEZ@1236|Gammaproteobacteria,1XHZJ@135619|Oceanospirillales	135619|Oceanospirillales	T	PFAM Metal-dependent phosphohydrolase, HD	-	-	-	-	-	-	-	-	-	-	-	-	DUF3391,HD,HD_5
k59_1566634_2	1537917.JU82_04840	2.77e-38	132.0	COG2863@1|root,COG2863@2|Bacteria,1NBPD@1224|Proteobacteria,42VXS@68525|delta/epsilon subdivisions,2YQ9N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
k59_1449334_1	159087.Daro_1826	5.43e-82	250.0	COG3221@1|root,COG3221@2|Bacteria,1MWFF@1224|Proteobacteria,2VMDZ@28216|Betaproteobacteria,2KZ2X@206389|Rhodocyclales	206389|Rhodocyclales	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
k59_977048_1	159087.Daro_3378	7.5e-29	105.0	COG0139@1|root,COG0139@2|Bacteria,1MW67@1224|Proteobacteria,2VR9B@28216|Betaproteobacteria,2KWD3@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19	ko:K01496	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04037	RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH
k59_977048_2	159087.Daro_3377	2.23e-69	209.0	COG0140@1|root,COG0140@2|Bacteria,1MZEE@1224|Proteobacteria,2VUN8@28216|Betaproteobacteria,2KWKQ@206389|Rhodocyclales	206389|Rhodocyclales	F	phosphoribosyl-ATP pyrophosphohydrolase	hisE	-	3.6.1.31	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-PH
k59_977048_3	1323663.AROI01000013_gene265	7.84e-08	50.4	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,1S3QE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	FG	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases	hinT	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019478,GO:0019752,GO:0043436,GO:0043530,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046144,GO:0046395,GO:0046416,GO:0046436,GO:0055130,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
k59_1585056_1	1408445.JHXP01000001_gene1577	1.37e-18	83.6	COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,1RMWC@1236|Gammaproteobacteria,1JCUK@118969|Legionellales	118969|Legionellales	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
k59_1585056_2	525244.HMPREF0023_2615	5.54e-57	180.0	COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,1S5XX@1236|Gammaproteobacteria,3NN51@468|Moraxellaceae	1236|Gammaproteobacteria	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
k59_1585056_3	1123377.AUIV01000012_gene774	2.27e-06	52.4	COG1651@1|root,COG1651@2|Bacteria,1RD39@1224|Proteobacteria,1S3U8@1236|Gammaproteobacteria,1X3T4@135614|Xanthomonadales	135614|Xanthomonadales	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	dsbC	-	5.3.4.1	ko:K03981	-	-	-	-	ko00000,ko01000,ko02044,ko03110	3.A.7.11.1	-	-	DsbC_N,Thioredoxin_2
k59_528409_1	1249480.B649_09420	1.38e-106	318.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,42MMF@68525|delta/epsilon subdivisions,2YMPB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Glycerol-3-phosphate dehydrogenase	glpC	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_17,Fer4_7,Fer4_8
k59_352279_1	709032.Sulku_1026	8.71e-89	263.0	2AHYJ@1|root,318BT@2|Bacteria,1Q04R@1224|Proteobacteria,42RKI@68525|delta/epsilon subdivisions,2YPAQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_117472_1	1537917.JU82_03250	3.34e-117	353.0	COG2199@1|root,COG2200@1|root,COG3620@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,COG3620@2|Bacteria,1MVJY@1224|Proteobacteria,42N7E@68525|delta/epsilon subdivisions,2YNE7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PFAM EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF
k59_1467648_1	935863.AWZR01000004_gene458	4.08e-06	52.8	2AQ2J@1|root,31F7Q@2|Bacteria,1QCMW@1224|Proteobacteria,1T8DC@1236|Gammaproteobacteria,1XAH4@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1056718_1	1123514.KB905899_gene488	1.23e-128	380.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,1RPZS@1236|Gammaproteobacteria,46072@72273|Thiotrichales	72273|Thiotrichales	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
k59_1056718_2	983545.Glaag_0837	2.45e-42	150.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,1RM7M@1236|Gammaproteobacteria,464CX@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
k59_1702478_1	1537917.JU82_10475	1.04e-22	89.0	COG2014@1|root,COG2014@2|Bacteria	2|Bacteria	F	Putative heavy-metal chelation	-	-	-	-	-	-	-	-	-	-	-	-	DUF364
k59_1702478_2	709032.Sulku_1535	1.21e-68	209.0	COG1433@1|root,COG1433@2|Bacteria,1Q859@1224|Proteobacteria,433F5@68525|delta/epsilon subdivisions,2YSQK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
k59_1702478_3	1249480.B649_06780	2.46e-65	209.0	COG0790@1|root,COG0790@2|Bacteria	2|Bacteria	S	beta-lactamase activity	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
k59_587104_1	1249480.B649_03880	2.44e-148	428.0	COG4733@1|root,COG4733@2|Bacteria,1N010@1224|Proteobacteria,42M7U@68525|delta/epsilon subdivisions,2YM7Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Fibronectin type 3 domain-containing protein	-	-	-	ko:K06882	-	-	-	-	ko00000	-	-	-	fn3
k59_1819905_2	1249480.B649_06930	1.67e-40	134.0	COG5554@1|root,COG5554@2|Bacteria,1Q3JU@1224|Proteobacteria,42XF5@68525|delta/epsilon subdivisions,2YQVJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	nitrogen fixation protein FixT	-	-	-	ko:K02593	-	-	-	-	ko00000	-	-	-	NifT
k59_1115441_1	749222.Nitsa_1401	1.41e-90	274.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,42REQ@68525|delta/epsilon subdivisions,2YSQU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	-
k59_1702493_1	1249480.B649_03460	5.73e-66	203.0	2AIM0@1|root,32I9V@2|Bacteria,1Q1S6@1224|Proteobacteria,42U9Z@68525|delta/epsilon subdivisions,2YPXP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1702493_2	1249480.B649_03465	3.75e-50	174.0	COG1256@1|root,COG1749@1|root,COG1256@2|Bacteria,COG1749@2|Bacteria,1MV2M@1224|Proteobacteria,42PBN@68525|delta/epsilon subdivisions,2YMGR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar hook-associated protein	flgK	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k59_1408951_2	1537917.JU82_03310	5.16e-57	179.0	COG1917@1|root,COG1917@2|Bacteria,1N2JS@1224|Proteobacteria,42TR3@68525|delta/epsilon subdivisions,2YSZN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
k59_645865_1	1168067.JAGP01000001_gene986	5.31e-160	473.0	COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,1RNMC@1236|Gammaproteobacteria,45ZS8@72273|Thiotrichales	72273|Thiotrichales	C	Belongs to the aconitase IPM isomerase family	-	-	4.2.1.3,4.2.1.99	ko:K01682	ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173	R01324,R01325,R01900,R04425	RC00497,RC00498,RC00618,RC01153	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_2_N,Aconitase_B_N
k59_352305_1	1537917.JU82_00195	1.02e-160	470.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2YNQA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
k59_1467674_1	1249480.B649_00340	4.06e-133	390.0	COG1293@1|root,COG1293@2|Bacteria,1R54S@1224|Proteobacteria,42MYG@68525|delta/epsilon subdivisions,2YT8X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	RNA-binding protein homologous to eukaryotic snRNP	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
k59_469738_2	497321.C664_12570	2.32e-44	158.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2VHBY@28216|Betaproteobacteria,2KVYU@206389|Rhodocyclales	206389|Rhodocyclales	F	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_645885_2	709032.Sulku_0303	2.67e-71	216.0	COG1699@1|root,COG1699@2|Bacteria,1N347@1224|Proteobacteria,42RNU@68525|delta/epsilon subdivisions,2YQ0C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum	-	-	-	ko:K13626	-	-	-	-	ko00000,ko02035	-	-	-	FliW
k59_176204_1	1537917.JU82_11800	1.97e-42	142.0	2AMMX@1|root,31CI0@2|Bacteria,1Q8WA@1224|Proteobacteria,42UGB@68525|delta/epsilon subdivisions,2YPW0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_234935_1	159087.Daro_0946	1.32e-136	398.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,2VI3U@28216|Betaproteobacteria,2KUMC@206389|Rhodocyclales	206389|Rhodocyclales	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_58825_1	397945.Aave_3422	5.72e-06	54.3	2EY8G@1|root,33RH1@2|Bacteria,1NTU8@1224|Proteobacteria,2W0YH@28216|Betaproteobacteria,4AHDZ@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1291629_1	1265503.KB905173_gene4128	1.47e-29	108.0	COG1694@1|root,COG1694@2|Bacteria,1N3XF@1224|Proteobacteria,1SSUP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Mazg nucleotide pyrophosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1291629_2	1121904.ARBP01000013_gene334	6.14e-25	103.0	COG1475@1|root,COG1475@2|Bacteria,4NQCX@976|Bacteroidetes,47QYM@768503|Cytophagia	976|Bacteroidetes	K	DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	ParBc
k59_352344_1	709032.Sulku_2527	1.27e-78	243.0	COG2199@1|root,COG3706@2|Bacteria,1QV14@1224|Proteobacteria,42NPJ@68525|delta/epsilon subdivisions,2YNH9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_352344_2	709032.Sulku_2528	1.27e-45	150.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,42RFN@68525|delta/epsilon subdivisions,2YP6C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
k59_293653_2	1537917.JU82_07445	6.4e-25	99.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
k59_1702552_1	709032.Sulku_0524	6.99e-81	252.0	COG5002@1|root,COG5002@2|Bacteria,1QZ29@1224|Proteobacteria,43CEG@68525|delta/epsilon subdivisions,2YTC2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_176222_1	159087.Daro_3075	3.03e-188	535.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2VJ55@28216|Betaproteobacteria,2KUZP@206389|Rhodocyclales	206389|Rhodocyclales	H	COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase	ilvI	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_1467710_2	1265505.ATUG01000002_gene2203	1.37e-08	61.2	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,42MPA@68525|delta/epsilon subdivisions,2WJ0Q@28221|Deltaproteobacteria,2MI3R@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
k59_587187_1	1537917.JU82_09950	4.06e-47	156.0	COG3166@1|root,COG3166@2|Bacteria,1Q1VC@1224|Proteobacteria,42UGS@68525|delta/epsilon subdivisions,2YPY1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	PFAM Fimbrial assembly family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_587187_2	1249480.B649_01310	1.01e-59	197.0	2BQX9@1|root,32JUG@2|Bacteria,1Q2H0@1224|Proteobacteria,42VPF@68525|delta/epsilon subdivisions,2YQMK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_704600_1	709032.Sulku_2537	3.87e-73	223.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,42QSI@68525|delta/epsilon subdivisions,2YNXJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	protein-L-isoaspartate O-methyltransferase	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
k59_704600_2	1249480.B649_11755	4.94e-57	183.0	COG0388@1|root,COG0388@2|Bacteria,1PZZZ@1224|Proteobacteria,42REP@68525|delta/epsilon subdivisions,2YP77@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
k59_1761285_1	948071.S4S2D9_9CAUD	1.68e-64	215.0	4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses  no RNA stage,4QRFY@28883|Caudovirales,4QNQ6@10744|Podoviridae	10744|Podoviridae	S	ribonucleoside-triphosphate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_528536_1	159087.Daro_4026	5.79e-74	224.0	COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,2VRIB@28216|Betaproteobacteria,2KWHF@206389|Rhodocyclales	206389|Rhodocyclales	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
k59_528536_2	1304883.KI912532_gene1007	2.96e-52	166.0	COG3027@1|root,COG3027@2|Bacteria,1N6YN@1224|Proteobacteria,2VVSV@28216|Betaproteobacteria,2KX9P@206389|Rhodocyclales	206389|Rhodocyclales	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
k59_528536_3	1304883.KI912532_gene1006	1.15e-29	106.0	2AN2U@1|root,31D0E@2|Bacteria,1QA1S@1224|Proteobacteria,2W724@28216|Betaproteobacteria,2KXH8@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	ko:K09892	-	-	-	-	ko00000,ko03036	-	-	-	-
k59_234977_2	663278.Ethha_0578	0.000782	42.4	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,247W7@186801|Clostridia,3WIPI@541000|Ruminococcaceae	186801|Clostridia	C	Aldehyde dehydrogenase family	-	-	1.2.1.32,1.2.1.39,1.2.1.60,1.2.1.8,1.2.1.85,1.2.1.99	ko:K00130,ko:K00146,ko:K00151,ko:K09472,ko:K10217	ko00260,ko00330,ko00350,ko00360,ko00362,ko00380,ko00622,ko00643,ko01100,ko01120,ko01220,map00260,map00330,map00350,map00360,map00362,map00380,map00622,map00643,map01100,map01120,map01220	M00038,M00136,M00533,M00555,M00569	R02536,R02565,R02566,R02762,R03889,R04418,R05353,R07417,R07418	RC00080,RC00218,RC00254	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_1174255_1	159087.Daro_0995	1.44e-125	360.0	COG0426@1|root,COG0426@2|Bacteria,1N2Y0@1224|Proteobacteria,2VH72@28216|Betaproteobacteria,2KUI3@206389|Rhodocyclales	206389|Rhodocyclales	C	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_1702576_1	1502852.FG94_01506	1.34e-46	155.0	COG1846@1|root,COG1846@2|Bacteria,1RCY7@1224|Proteobacteria,2VSV9@28216|Betaproteobacteria,477R0@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
k59_1056807_1	1249480.B649_04995	3.87e-34	125.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2YMY9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_1056807_2	709032.Sulku_1171	6.41e-56	176.0	COG1393@1|root,COG1393@2|Bacteria,1QDI7@1224|Proteobacteria,42U8X@68525|delta/epsilon subdivisions,2YPXC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	ArsC
k59_1702577_1	1537917.JU82_04710	2.09e-66	207.0	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,42MMC@68525|delta/epsilon subdivisions,2YMS8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the TtcA family	ttcA	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
k59_1702577_2	1249480.B649_08230	1.92e-129	371.0	COG0775@1|root,COG0775@2|Bacteria,1MY5S@1224|Proteobacteria,42MBG@68525|delta/epsilon subdivisions,2YMHE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	pfs	-	3.2.2.30,3.2.2.9	ko:K18284	ko00130,ko00270,ko01100,ko01110,ko01230,map00130,map00270,map01100,map01110,map01230	M00034,M00609	R00194,R01401,R10668	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
k59_254_1	709032.Sulku_0294	2.62e-136	394.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,42MUW@68525|delta/epsilon subdivisions,2YMJW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N
k59_411108_1	202952.BBLI01000072_gene3507	2.65e-05	51.6	COG5527@1|root,COG5527@2|Bacteria,1RD9C@1224|Proteobacteria,1S4ZG@1236|Gammaproteobacteria,3NJHN@468|Moraxellaceae	1236|Gammaproteobacteria	L	Initiator Replication protein	-	-	-	-	-	-	-	-	-	-	-	-	Rep_3
k59_763326_1	387093.SUN_0650	2.72e-46	152.0	2DQ0J@1|root,3348C@2|Bacteria,1NBQ2@1224|Proteobacteria,42UFN@68525|delta/epsilon subdivisions,2YPUT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Chemoreceptor zinc-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CZB
k59_763326_2	387093.SUN_1193	3.33e-35	129.0	COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,42P4E@68525|delta/epsilon subdivisions,2YNAC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs	truD	-	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
k59_822085_1	1249480.B649_11150	2.32e-20	85.9	2AIVF@1|root,319NT@2|Bacteria,1Q3D4@1224|Proteobacteria,42X4I@68525|delta/epsilon subdivisions,2YQUS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Flagellar FliJ protein	-	-	-	-	-	-	-	-	-	-	-	-	FliJ
k59_822085_3	1123487.KB892866_gene1775	9.21e-63	201.0	COG0671@1|root,COG0671@2|Bacteria,1RFUF@1224|Proteobacteria,2VRMF@28216|Betaproteobacteria,2KWEU@206389|Rhodocyclales	206389|Rhodocyclales	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2,PAP2_3
k59_58922_1	525898.Sdel_1998	1.61e-104	308.0	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,42QX7@68525|delta/epsilon subdivisions,2YRDE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	PFAM IstB domain protein ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
k59_1702643_2	1249480.B649_07190	1.54e-66	211.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	CarbopepD_reg_2,TonB_2,TonB_C
k59_1233048_1	1249480.B649_11340	1.72e-56	192.0	COG2885@1|root,COG2885@2|Bacteria,1QW22@1224|Proteobacteria,42NCQ@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	OmpA MotB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,OmpA
k59_1643946_1	1537917.JU82_09500	2.1e-51	164.0	COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,42TIT@68525|delta/epsilon subdivisions,2YPXD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
k59_1643946_2	1537917.JU82_09505	5.64e-117	335.0	COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,42NSE@68525|delta/epsilon subdivisions,2YMUG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
k59_353448_2	1537917.JU82_06810	1.21e-58	201.0	COG0835@1|root,COG0835@2|Bacteria,1QVCF@1224|Proteobacteria,42M0F@68525|delta/epsilon subdivisions,2YNAP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	PFAM CheW domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CheW,dCache_1
k59_412378_1	1123517.JOMR01000001_gene1133	1.5e-72	240.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,1RMY0@1236|Gammaproteobacteria,46003@72273|Thiotrichales	72273|Thiotrichales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
k59_412378_2	56107.Cylst_0844	6.5e-05	42.4	2EK16@1|root,33DRP@2|Bacteria,1GJ1M@1117|Cyanobacteria,1HQ1Y@1161|Nostocales	1117|Cyanobacteria	S	SPTR Genome sequencing data, contig C323	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_823365_1	159087.Daro_3853	2.19e-90	276.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,2VHBB@28216|Betaproteobacteria,2KUR1@206389|Rhodocyclales	206389|Rhodocyclales	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
k59_294847_1	29581.BW37_05273	1.66e-25	110.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2VMMZ@28216|Betaproteobacteria,473HK@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	diguanylate cyclase	wspR	-	2.7.7.65	ko:K11444	ko02020,ko02025,map02020,map02025	M00509	-	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,HATPase_c,Response_reg
k59_1175716_2	1537917.JU82_08655	3.62e-88	264.0	2C2VD@1|root,338G0@2|Bacteria,1P3HX@1224|Proteobacteria,42NM6@68525|delta/epsilon subdivisions,2YM9Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1057928_1	62928.azo3835	1.53e-73	234.0	COG1840@1|root,COG1840@2|Bacteria,1MWWI@1224|Proteobacteria,2VIG9@28216|Betaproteobacteria,2KY27@206389|Rhodocyclales	206389|Rhodocyclales	P	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_6
k59_412393_1	159087.Daro_0312	2.39e-118	375.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,2VHF3@28216|Betaproteobacteria,2KV0Q@206389|Rhodocyclales	206389|Rhodocyclales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_588506_1	640081.Dsui_2183	6.12e-22	92.4	COG0676@1|root,COG0676@2|Bacteria,1Q7VN@1224|Proteobacteria,2VKZK@28216|Betaproteobacteria,2KUFY@206389|Rhodocyclales	206389|Rhodocyclales	G	Belongs to the glucose-6-phosphate 1-epimerase family	-	-	5.1.3.15	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	-	R02739	RC00563	ko00000,ko00001,ko01000	-	-	-	Aldose_epim
k59_588506_2	159087.Daro_1089	4.2e-43	148.0	COG0664@1|root,COG0664@2|Bacteria,1RDWC@1224|Proteobacteria,2VR67@28216|Betaproteobacteria,2KWRQ@206389|Rhodocyclales	206389|Rhodocyclales	K	helix_turn_helix, cAMP Regulatory protein	-	-	-	ko:K21555	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2
k59_471265_1	506534.Rhein_4007	1.54e-06	57.4	COG2982@1|root,COG3210@1|root,COG3637@1|root,COG4932@1|root,COG2982@2|Bacteria,COG3210@2|Bacteria,COG3637@2|Bacteria,COG4932@2|Bacteria,1QUXB@1224|Proteobacteria	1224|Proteobacteria	U	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Cadherin_3,Calx-beta,DUF11,DUF4347,He_PIG,OmpA_membrane,PATR,VCBS
k59_118904_1	159087.Daro_2188	7.65e-93	301.0	COG3523@1|root,COG3523@2|Bacteria,1MV3D@1224|Proteobacteria,2VJ0M@28216|Betaproteobacteria,2KV24@206389|Rhodocyclales	206389|Rhodocyclales	S	function. A few members resemble the ImcF protein, which has been proposed to be involved in Vibrio cholerae cell surface reorganisation that results in increased adherence to epithelial cells line and increased conjugation frequency	-	-	-	ko:K11891	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	IcmF-related,IcmF_C,ImcF-related_N
k59_647669_1	1132855.KB913035_gene2377	3.1e-62	195.0	2CDCV@1|root,308Y1@2|Bacteria,1N74F@1224|Proteobacteria,2VSMP@28216|Betaproteobacteria,2KMRH@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_647669_2	1502770.JQMG01000001_gene2310	1.34e-06	48.9	COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,2VGZY@28216|Betaproteobacteria,2KM07@206350|Nitrosomonadales	206350|Nitrosomonadales	K	aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
k59_294865_1	159087.Daro_1550	1.51e-121	357.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VIF8@28216|Betaproteobacteria,2KV8Q@206389|Rhodocyclales	206389|Rhodocyclales	I	Belongs to the thiolase family	-	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
k59_1586651_1	159087.Daro_0008	1.51e-82	273.0	COG0784@1|root,COG2198@1|root,COG5000@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG5000@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,2WGIN@28216|Betaproteobacteria,2KZWN@206389|Rhodocyclales	206389|Rhodocyclales	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_4,PAS_9,Response_reg
k59_60197_1	159087.Daro_0949	6.98e-78	232.0	COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,2VSI3@28216|Betaproteobacteria,2KWN5@206389|Rhodocyclales	206389|Rhodocyclales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
k59_60197_2	640081.Dsui_3049	1.39e-114	328.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,2VIWK@28216|Betaproteobacteria,2KVKP@206389|Rhodocyclales	206389|Rhodocyclales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
k59_60197_3	1304883.KI912532_gene21	1.56e-33	120.0	COG0852@1|root,COG0852@2|Bacteria,1MX4B@1224|Proteobacteria,2VHHV@28216|Betaproteobacteria,2KUVB@206389|Rhodocyclales	206389|Rhodocyclales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
k59_294867_1	1249480.B649_04180	2.01e-116	348.0	COG1418@1|root,COG1418@2|Bacteria,1P7YA@1224|Proteobacteria,42KZ8@68525|delta/epsilon subdivisions,2YMQS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
k59_1410118_1	646529.Desaci_0820	3.81e-25	111.0	COG2199@1|root,COG3437@1|root,COG4936@1|root,COG2199@2|Bacteria,COG3437@2|Bacteria,COG4936@2|Bacteria,1TQ0S@1239|Firmicutes,24Y6H@186801|Clostridia,267AY@186807|Peptococcaceae	186801|Clostridia	T	diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HAMP,HD,HD_5,PAS_9,dCache_1
k59_1191388_2	709032.Sulku_0548	1.47e-45	150.0	COG3012@1|root,COG3012@2|Bacteria,1Q5V3@1224|Proteobacteria,42UFW@68525|delta/epsilon subdivisions,2YPTX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	SEC-C motif	-	-	-	ko:K09858	-	-	-	-	ko00000	-	-	-	SEC-C
k59_490053_2	387093.SUN_1509	3.89e-34	124.0	COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,42M4G@68525|delta/epsilon subdivisions,2YR6C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
k59_1429590_1	204773.HEAR2736	3.5e-46	162.0	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,2VH1E@28216|Betaproteobacteria,4728U@75682|Oxalobacteraceae	28216|Betaproteobacteria	F	Amidohydrolase family	pyrX	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
k59_192519_1	118168.MC7420_4451	4.65e-19	91.7	COG2199@1|root,COG2202@1|root,COG3829@1|root,COG3850@1|root,COG4191@1|root,COG4251@1|root,COG5002@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,COG3829@2|Bacteria,COG3850@2|Bacteria,COG4191@2|Bacteria,COG4251@2|Bacteria,COG5002@2|Bacteria,1GHCI@1117|Cyanobacteria,1HHXQ@1150|Oscillatoriales	1117|Cyanobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
k59_309192_1	1249480.B649_03150	2.49e-28	105.0	COG0662@1|root,COG0662@2|Bacteria,1QUHG@1224|Proteobacteria,43BPC@68525|delta/epsilon subdivisions,2YQZE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	PFAM Cupin 2 conserved barrel domain protein	-	-	-	ko:K11312	-	-	-	-	ko00000	-	-	-	Cupin_2
k59_309192_3	1249480.B649_03160	8.92e-61	190.0	COG1331@1|root,COG1331@2|Bacteria,1N55I@1224|Proteobacteria,42VTZ@68525|delta/epsilon subdivisions,2YQJ6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Highly conserved protein containing a thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH
k59_309192_4	709032.Sulku_0639	3.3e-28	111.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,42M3R@68525|delta/epsilon subdivisions,2YN91@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
k59_718017_2	1249480.B649_02660	2.26e-35	120.0	COG4895@1|root,COG4895@2|Bacteria,1N7TD@1224|Proteobacteria,42V1D@68525|delta/epsilon subdivisions,2YQJ3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Uncharacterized conserved protein (DUF2196)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2196
k59_1191417_1	981223.AIED01000001_gene1817	1.08e-31	113.0	COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,1S8RT@1236|Gammaproteobacteria,3NNWP@468|Moraxellaceae	1236|Gammaproteobacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
k59_1191417_2	395493.BegalDRAFT_1244	4.08e-42	145.0	COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,1RNJ2@1236|Gammaproteobacteria,460XQ@72273|Thiotrichales	72273|Thiotrichales	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
k59_1191417_3	717773.Thicy_0492	1.15e-72	225.0	COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,1RMWC@1236|Gammaproteobacteria,460F5@72273|Thiotrichales	72273|Thiotrichales	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
k59_368362_1	1484158.PSNIH1_14300	8.12e-30	116.0	COG0676@1|root,COG0676@2|Bacteria,1Q7VN@1224|Proteobacteria,1RQK0@1236|Gammaproteobacteria,3VXS8@53335|Pantoea	1236|Gammaproteobacteria	G	Belongs to the glucose-6-phosphate 1-epimerase family	yeaD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716	5.1.3.15	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	-	R02739	RC00563	ko00000,ko00001,ko01000	-	-	-	Aldose_epim
k59_252880_1	1265502.KB905984_gene27	2.46e-80	252.0	COG1388@1|root,COG1388@2|Bacteria,1QYEA@1224|Proteobacteria,2WHEF@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Pfam:DUF3380	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Muraidase
k59_1254322_1	1537917.JU82_04470	6.92e-117	340.0	COG2833@1|root,COG2833@2|Bacteria,1MW0V@1224|Proteobacteria,42KZ6@68525|delta/epsilon subdivisions,2YMPZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	hmm pf04305	-	-	-	-	-	-	-	-	-	-	-	-	DUF455
k59_1841095_1	666681.M301_0449	1.07e-88	274.0	COG4235@1|root,COG4235@2|Bacteria,1MY4J@1224|Proteobacteria,2VQ05@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Cytochrome c-type biogenesis protein	cycH	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	TPR_16,TPR_2
k59_192567_1	395494.Galf_1259	2.2e-74	227.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,2VSRT@28216|Betaproteobacteria,44VTX@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
k59_490125_1	1165841.SULAR_05648	7.56e-36	139.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	glnL	-	-	ko:K07719	ko02020,map02020	M00518	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,TPR_16,TPR_19,TPR_8,YcbB
k59_841343_1	1249480.B649_04785	4.85e-161	477.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,42M4I@68525|delta/epsilon subdivisions,2YMFT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_1020017_1	1132855.KB913035_gene1076	1.14e-103	314.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,2VHVA@28216|Betaproteobacteria,2KMB4@206350|Nitrosomonadales	206350|Nitrosomonadales	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
k59_252914_1	326298.Suden_0929	1.15e-45	167.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2YMKB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
k59_1486225_1	159087.Daro_3408	3.14e-73	230.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,2VI1J@28216|Betaproteobacteria,2KU71@206389|Rhodocyclales	206389|Rhodocyclales	NU	type II secretion system protein	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
k59_1486225_2	1163617.SCD_n00571	6.52e-16	77.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	type II secretion system protein E	xcpR	-	-	ko:K02454,ko:K02652,ko:K12276	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
k59_137858_1	159087.Daro_3944	1.96e-113	345.0	COG4772@1|root,COG4772@2|Bacteria,1QVCH@1224|Proteobacteria,2WGQ6@28216|Betaproteobacteria,2KVN0@206389|Rhodocyclales	206389|Rhodocyclales	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_1254371_1	709032.Sulku_1385	3.64e-105	323.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,42M9Q@68525|delta/epsilon subdivisions,2YNFG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.20.2.1,1.20.9.1,1.7.7.2	ko:K00367,ko:K00372,ko:K08356	ko00910,ko01120,map00910,map01120	M00531	R00791,R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.6	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_779760_1	1537917.JU82_06810	1.83e-210	606.0	COG0835@1|root,COG0835@2|Bacteria,1QVCF@1224|Proteobacteria,42M0F@68525|delta/epsilon subdivisions,2YNAP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	PFAM CheW domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CheW,dCache_1
k59_898690_1	1165841.SULAR_05828	3.17e-133	402.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,42MKB@68525|delta/epsilon subdivisions,2YMIZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
k59_1547521_1	1165841.SULAR_00385	9.47e-27	100.0	29ZBM@1|root,30MA5@2|Bacteria,1QB0B@1224|Proteobacteria,42XGS@68525|delta/epsilon subdivisions,2YQT0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_192613_1	563040.Saut_0948	1.46e-104	312.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,42NH1@68525|delta/epsilon subdivisions,2YR1T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Phosphate transporter family	-	-	-	ko:K03306,ko:K16322	-	-	-	-	ko00000,ko02000	2.A.20,2.A.20.1	-	-	PHO4
k59_137910_1	305700.B447_01761	2.59e-83	249.0	COG1142@1|root,COG1142@2|Bacteria,1MWE1@1224|Proteobacteria,2VJ9U@28216|Betaproteobacteria,2KW51@206389|Rhodocyclales	206389|Rhodocyclales	C	4Fe-4S ferredoxin, iron-sulfur binding	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_11
k59_137910_2	62928.azo2930	3.49e-116	349.0	COG2414@1|root,COG2414@2|Bacteria,1MWBB@1224|Proteobacteria,2VJ8P@28216|Betaproteobacteria,2KVX2@206389|Rhodocyclales	206389|Rhodocyclales	C	aldehyde ferredoxin oxidoreductase	aorA	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
k59_1429736_1	159087.Daro_0085	4.48e-38	137.0	COG5380@1|root,COG5380@2|Bacteria,1N6UY@1224|Proteobacteria,2VRU4@28216|Betaproteobacteria,2KX74@206389|Rhodocyclales	206389|Rhodocyclales	O	lipid catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1429736_2	744980.TRICHSKD4_4052	5.09e-09	53.9	COG3313@1|root,COG3313@2|Bacteria	2|Bacteria	S	Fe-S protein	RSC1457	-	-	ko:K06938	-	-	-	-	ko00000	-	-	-	Cys_rich_CWC,DUF1289,NUDIX
k59_1429736_3	522306.CAP2UW1_4323	3.04e-12	61.6	COG3313@1|root,COG3313@2|Bacteria	2|Bacteria	S	Fe-S protein	RSC1457	-	-	ko:K06938	-	-	-	-	ko00000	-	-	-	Cys_rich_CWC,DUF1289,NUDIX
k59_779806_1	1110502.TMO_1786	6.34e-05	47.0	COG0583@1|root,COG0583@2|Bacteria,1PX1B@1224|Proteobacteria,2TUE7@28211|Alphaproteobacteria,2JV50@204441|Rhodospirillales	204441|Rhodospirillales	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_1075580_2	1537917.JU82_04700	2.26e-82	250.0	COG0388@1|root,COG0388@2|Bacteria,1RIQI@1224|Proteobacteria,42T6J@68525|delta/epsilon subdivisions,2YP46@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
k59_1841199_2	709032.Sulku_0355	1.21e-29	115.0	COG2199@1|root,COG3829@1|root,COG3706@2|Bacteria,COG3829@2|Bacteria,1R7HC@1224|Proteobacteria,42YVM@68525|delta/epsilon subdivisions,2YRBE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_9
k59_1662095_1	123214.PERMA_1456	1.21e-72	233.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
k59_1662095_2	123214.PERMA_1459	2.29e-50	174.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
k59_17862_1	1110502.TMO_0592	3.37e-43	153.0	COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,2TS5I@28211|Alphaproteobacteria,2JPA3@204441|Rhodospirillales	204441|Rhodospirillales	S	Peptidogalycan biosysnthesis/recognition	-	-	-	ko:K09919	-	-	-	-	ko00000	-	-	-	FemAB_like
k59_17862_2	1266914.ATUK01000010_gene1220	1.22e-22	95.5	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,1RMEX@1236|Gammaproteobacteria,1WWPK@135613|Chromatiales	135613|Chromatiales	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_841444_1	631362.Thi970DRAFT_01582	1.03e-88	270.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,1RN4H@1236|Gammaproteobacteria,1WWV1@135613|Chromatiales	135613|Chromatiales	L	PFAM Endonuclease Exonuclease phosphatase	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
k59_667382_1	709032.Sulku_0345	2.1e-75	236.0	COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,42QJ2@68525|delta/epsilon subdivisions,2YNBV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COGs COG3864 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
k59_1778879_1	1537917.JU82_02300	4.87e-146	425.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,42N3P@68525|delta/epsilon subdivisions,2YM8F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EG	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
k59_1429793_1	640081.Dsui_2099	5.42e-74	226.0	COG1595@1|root,COG1595@2|Bacteria,1R3SM@1224|Proteobacteria,2VS23@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_1191567_1	1537917.JU82_08065	2.86e-34	125.0	COG1242@1|root,COG1242@2|Bacteria,1MUYF@1224|Proteobacteria,42PX9@68525|delta/epsilon subdivisions,2YN2U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Radical SAM protein	-	-	-	ko:K07139	-	-	-	-	ko00000	-	-	-	Radical_SAM,Radical_SAM_C
k59_1191567_2	1537917.JU82_08060	1.78e-76	240.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,42MDB@68525|delta/epsilon subdivisions,2YMF9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7,Pribosyltran
k59_309315_1	62928.azo2356	2.78e-14	71.6	COG0003@1|root,COG0003@2|Bacteria,1MUTX@1224|Proteobacteria,2VK65@28216|Betaproteobacteria,2KUEH@206389|Rhodocyclales	206389|Rhodocyclales	P	Anion-transporting ATPase	arsA	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase,CbiA
k59_309315_2	1121035.AUCH01000004_gene417	2.56e-67	205.0	2DMHQ@1|root,32RMG@2|Bacteria,1RI3A@1224|Proteobacteria,2VSJE@28216|Betaproteobacteria,2KWJP@206389|Rhodocyclales	206389|Rhodocyclales	S	Arsenical resistance operon trans-acting repressor ArsD	arsD	-	-	-	-	-	-	-	-	-	-	-	ArsD
k59_309315_3	338966.Ppro_0841	5.87e-30	115.0	COG0798@1|root,COG0798@2|Bacteria,1MUXY@1224|Proteobacteria,42M0Z@68525|delta/epsilon subdivisions,2WK36@28221|Deltaproteobacteria,43SE0@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Sodium Bile acid symporter family	arsB	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
k59_490251_1	749222.Nitsa_1753	6.51e-138	402.0	COG0446@1|root,COG0446@2|Bacteria,1PWV7@1224|Proteobacteria,42QCM@68525|delta/epsilon subdivisions,2YND4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COGs COG1252 NADH dehydrogenase FAD-containing subunit	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_1191575_1	1165841.SULAR_06883	1.4e-163	488.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,42N8X@68525|delta/epsilon subdivisions,2YMGZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_1547631_1	1249480.B649_05345	7.62e-158	462.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,42WJ0@68525|delta/epsilon subdivisions,2YQJR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	PFAM TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_1778902_1	387093.SUN_1675	6.3e-91	283.0	COG1450@1|root,COG1450@2|Bacteria,1MVNC@1224|Proteobacteria,43BJ2@68525|delta/epsilon subdivisions,2YN49@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Type II and III secretion system protein	ctsD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	STN,Secretin,Secretin_N_2
k59_1136252_1	391735.Veis_3972	5.29e-117	349.0	COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,2VIJH@28216|Betaproteobacteria,4AA4J@80864|Comamonadaceae	28216|Betaproteobacteria	P	ABC-type nitrate sulfonate bicarbonate transport	nrtA	-	-	ko:K02051,ko:K15576	ko00910,ko02010,map00910,map02010	M00188,M00438	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.16.1,3.A.1.16.2,3.A.1.17	-	-	NMT1_2
k59_667445_1	159087.Daro_0292	1.63e-35	128.0	COG0583@1|root,COG0583@2|Bacteria,1MVHT@1224|Proteobacteria,2VHF0@28216|Betaproteobacteria,2KV22@206389|Rhodocyclales	206389|Rhodocyclales	K	LysR substrate binding domain	-	-	-	ko:K03717	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k59_667445_2	159087.Daro_0293	4.9e-33	121.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,2VIVB@28216|Betaproteobacteria,2KVBC@206389|Rhodocyclales	206389|Rhodocyclales	O	Belongs to the peptidase M48B family	-	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
k59_253050_2	1249480.B649_11645	3.06e-25	103.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,42MEU@68525|delta/epsilon subdivisions,2YMUF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
k59_368535_1	62928.azo3335	5.9e-35	138.0	COG3170@1|root,COG3170@2|Bacteria,1RE27@1224|Proteobacteria,2VRNH@28216|Betaproteobacteria,2KW0V@206389|Rhodocyclales	206389|Rhodocyclales	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_368535_2	522306.CAP2UW1_4047	4.22e-27	104.0	COG0327@1|root,COG0327@2|Bacteria,1MVUN@1224|Proteobacteria,2VIX1@28216|Betaproteobacteria,1KPX2@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	SecretomeP prediction	ybgI	-	-	-	-	-	-	-	-	-	-	-	NIF3
k59_1254546_1	1304883.KI912532_gene641	1.1e-54	175.0	COG2087@1|root,COG2087@2|Bacteria,1RH0A@1224|Proteobacteria,2VSQI@28216|Betaproteobacteria,2KWMR@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate	cobU	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU
k59_1254546_2	1304883.KI912532_gene642	1.56e-15	73.6	COG0642@1|root,COG2205@2|Bacteria,1R9ZT@1224|Proteobacteria,2VPPS@28216|Betaproteobacteria,2KZJR@206389|Rhodocyclales	206389|Rhodocyclales	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1778936_1	1437609.BCAL_1663	1.73e-19	93.6	COG1215@1|root,COG1216@1|root,COG1215@2|Bacteria,COG1216@2|Bacteria,2I2H3@201174|Actinobacteria,4D0HF@85004|Bifidobacteriales	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
k59_138026_1	1537917.JU82_06735	7.61e-126	363.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,42MVM@68525|delta/epsilon subdivisions,2YMMR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxC
k59_138026_2	1249480.B649_02260	1.11e-73	224.0	COG1214@1|root,COG1214@2|Bacteria,1Q1J6@1224|Proteobacteria,42TUF@68525|delta/epsilon subdivisions,2YQ3R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	COG1214 Inactive homolog of metal-dependent proteases	tsaB	-	-	-	-	-	-	-	-	-	-	-	-
k59_138026_3	709032.Sulku_0458	2.06e-201	558.0	COG0083@1|root,COG0083@2|Bacteria,1MW8I@1224|Proteobacteria,42M9H@68525|delta/epsilon subdivisions,2YMZ3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
k59_138026_4	1249480.B649_02270	3.58e-34	118.0	COG2740@1|root,COG2740@2|Bacteria	2|Bacteria	K	Nucleic-acid-binding protein implicated in transcription termination	ylxR	-	-	ko:K02600,ko:K07742	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	DUF448
k59_779945_1	709032.Sulku_0836	2.18e-73	246.0	COG2202@1|root,COG2203@1|root,COG3452@1|root,COG5001@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3452@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YMHP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GGDEF,PAS_4,PAS_9
k59_606271_2	709032.Sulku_0488	3.11e-115	350.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,42NN7@68525|delta/epsilon subdivisions,2YMKH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
k59_1778951_1	1304883.KI912532_gene1928	4.91e-102	302.0	COG2307@1|root,COG2307@2|Bacteria,1MVZK@1224|Proteobacteria,2VIB5@28216|Betaproteobacteria,2KV8E@206389|Rhodocyclales	206389|Rhodocyclales	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
k59_1136320_1	1132855.KB913035_gene655	5.35e-93	290.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,2VHNX@28216|Betaproteobacteria,2KKF0@206350|Nitrosomonadales	206350|Nitrosomonadales	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
k59_1191651_1	563040.Saut_0449	2.33e-30	122.0	COG1450@1|root,COG1450@2|Bacteria,1QXWT@1224|Proteobacteria,43CKP@68525|delta/epsilon subdivisions,2YN73@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	COG1450 Type II secretory pathway component PulD	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N_2
k59_1547734_1	1123518.ARWI01000001_gene415	1.63e-75	244.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,1RMMD@1236|Gammaproteobacteria,46098@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_1308808_1	1537917.JU82_04335	2.23e-65	215.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1R5RS@1224|Proteobacteria,42M3K@68525|delta/epsilon subdivisions,2YN6E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	PFAM biotin lipoyl attachment domain-containing protein	pycB	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
k59_1308808_2	1249480.B649_01475	1e-48	170.0	COG1883@1|root,COG1883@2|Bacteria,1MV0G@1224|Proteobacteria,42MH1@68525|delta/epsilon subdivisions,2YNK3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1883 Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit	-	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
k59_1308812_1	1304883.KI912532_gene392	5.71e-106	324.0	COG4670@1|root,COG4670@2|Bacteria,1MUJW@1224|Proteobacteria,2VH8B@28216|Betaproteobacteria,2KVP5@206389|Rhodocyclales	206389|Rhodocyclales	I	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons	-	-	2.8.3.1	ko:K01026	ko00620,ko00640,ko00643,ko01100,ko01120,map00620,map00640,map00643,map01100,map01120	-	R00928,R01449,R05508	RC00012,RC00014,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
k59_844198_1	1537917.JU82_11275	1.77e-97	295.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,42MFC@68525|delta/epsilon subdivisions,2YMN5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iIT341.HP0976	AAA_26,Aminotran_3
k59_782931_1	1537917.JU82_01850	2.45e-117	341.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,42P3I@68525|delta/epsilon subdivisions,2YMYB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
k59_782931_2	1537917.JU82_01845	5.1e-101	298.0	COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,42MZF@68525|delta/epsilon subdivisions,2YMQX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
k59_1488774_1	1165841.SULAR_07935	2.67e-31	119.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,42MGM@68525|delta/epsilon subdivisions,2YMUV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
k59_1488774_2	387093.SUN_2339	1.58e-69	212.0	COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,42SRC@68525|delta/epsilon subdivisions,2YP4I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
k59_430830_1	1537917.JU82_04360	5.07e-115	339.0	COG1565@1|root,COG1565@2|Bacteria,1QNDB@1224|Proteobacteria,42MQ8@68525|delta/epsilon subdivisions,2YNBU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
k59_430830_2	563040.Saut_1369	2.17e-81	258.0	COG1538@1|root,COG1538@2|Bacteria,1Q066@1224|Proteobacteria,42RNJ@68525|delta/epsilon subdivisions,2YNZR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_670755_1	317025.Tcr_0156	1.86e-116	347.0	COG2041@1|root,COG2041@2|Bacteria,1MX9E@1224|Proteobacteria,1RP2M@1236|Gammaproteobacteria,461KA@72273|Thiotrichales	72273|Thiotrichales	S	Mo-co oxidoreductase dimerisation domain	-	-	-	ko:K17225	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	Mo-co_dimer,Oxidored_molyb
k59_961478_1	1165841.SULAR_08532	8.42e-60	196.0	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,42MBB@68525|delta/epsilon subdivisions,2YMFZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
k59_1433194_1	317025.Tcr_1950	1.17e-96	290.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,1T02D@1236|Gammaproteobacteria,46181@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
k59_1139135_1	1537917.JU82_11860	4.25e-25	97.8	2BTJ1@1|root,32NRK@2|Bacteria,1Q3XC@1224|Proteobacteria,42RS4@68525|delta/epsilon subdivisions,2YPVI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Lipopolysaccharide-assembly	-	-	-	-	-	-	-	-	-	-	-	-	LptE
k59_1433217_1	1317124.DW2_08412	1.98e-08	60.5	COG1283@1|root,COG1283@2|Bacteria,1MUDE@1224|Proteobacteria,2TRF9@28211|Alphaproteobacteria,2XNU3@285107|Thioclava	28211|Alphaproteobacteria	P	Na+/Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans
k59_141001_2	159087.Daro_0214	1.87e-15	76.3	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,2VHY4@28216|Betaproteobacteria,2KUHK@206389|Rhodocyclales	206389|Rhodocyclales	U	Type 4 fimbrial biogenesis protein	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
k59_1334213_1	709032.Sulku_0465	1.87e-132	388.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,42MSB@68525|delta/epsilon subdivisions,2YMBS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
k59_925871_1	159087.Daro_1823	5.22e-79	246.0	COG2265@1|root,COG2265@2|Bacteria,1MY45@1224|Proteobacteria,2VMIG@28216|Betaproteobacteria,2KU7V@206389|Rhodocyclales	206389|Rhodocyclales	J	Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA)	trmA	-	2.1.1.35	ko:K00557	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_U5-meth_tr
k59_1803788_2	1537917.JU82_02665	9.36e-61	189.0	COG0537@1|root,COG0537@2|Bacteria,1MZVD@1224|Proteobacteria,42TMC@68525|delta/epsilon subdivisions,2YPSJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	FG	(HIT) family	-	-	-	-	-	-	-	-	-	-	-	-	HIT
k59_454118_1	709032.Sulku_1757	1.46e-89	290.0	COG1305@1|root,COG4196@1|root,COG1305@2|Bacteria,COG4196@2|Bacteria,1MVAG@1224|Proteobacteria,42P26@68525|delta/epsilon subdivisions,2YN89@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Putative amidoligase enzyme (DUF2126)	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,DUF2126,Transglut_core
k59_864437_1	536232.CLM_0373	6.28e-67	230.0	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,2490U@186801|Clostridia,36EG3@31979|Clostridiaceae	186801|Clostridia	Q	TIGRFAM amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_1218363_1	1537917.JU82_03925	1e-103	318.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42MBE@68525|delta/epsilon subdivisions,2YNGN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	abc transporter atp-binding protein	-	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k59_1630026_2	1150621.SMUL_2622	6.85e-27	109.0	COG0607@1|root,COG0607@2|Bacteria,1REGB@1224|Proteobacteria,43DB1@68525|delta/epsilon subdivisions,2YTI2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_1630026_3	998674.ATTE01000001_gene3459	1.11e-07	52.4	COG0607@1|root,COG0607@2|Bacteria,1REGB@1224|Proteobacteria,1S580@1236|Gammaproteobacteria,462B6@72273|Thiotrichales	72273|Thiotrichales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_1687304_1	1195236.CTER_2432	2.39e-23	109.0	COG1404@1|root,COG3209@1|root,COG1404@2|Bacteria,COG3209@2|Bacteria,1TR8F@1239|Firmicutes,248C6@186801|Clostridia,3WNZA@541000|Ruminococcaceae	186801|Clostridia	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,Peptidase_S8,RHS_repeat
k59_391782_1	159087.Daro_3327	8.63e-43	145.0	COG2863@1|root,COG2863@2|Bacteria,1N7W9@1224|Proteobacteria,2WEG6@28216|Betaproteobacteria,2KW5A@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome C oxidase, cbb3-type, subunit III	cc43	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
k59_391782_2	1454004.AW11_00113	1.71e-47	164.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,2VHJ9@28216|Betaproteobacteria,1KPTW@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Putative modulator of DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
k59_1803819_1	1537917.JU82_09715	2.72e-134	411.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,42MWW@68525|delta/epsilon subdivisions,2YMMH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_990206_1	1165841.SULAR_07910	3.73e-37	127.0	COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,42RE3@68525|delta/epsilon subdivisions,2YP8H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
k59_40675_1	1049564.TevJSym_bl00230	2.91e-29	120.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,1RMP1@1236|Gammaproteobacteria,1J4PG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	N-acetylmuramoyl-L-alanine amidase	amiC	GO:0000003,GO:0000910,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0008745,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0019954,GO:0022402,GO:0022414,GO:0030288,GO:0030313,GO:0031975,GO:0032505,GO:0042597,GO:0043093,GO:0044464,GO:0051301,GO:0061783	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	iPC815.YPO1023,iSDY_1059.SDY_3034,iYL1228.KPN_03225	AMIN,Amidase_3,LysM
k59_1218406_2	1249480.B649_09235	2.29e-43	147.0	COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,42SQE@68525|delta/epsilon subdivisions,2YPHI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	GO:0003674,GO:0003824,GO:0004141,GO:0016874,GO:0016879,GO:0016882	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
k59_1870222_1	399795.CtesDRAFT_PD3588	8.77e-97	310.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2VHCZ@28216|Betaproteobacteria,4A9J4@80864|Comamonadaceae	28216|Betaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
k59_1870227_1	1304883.KI912532_gene2928	7.73e-60	209.0	COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,2VIMP@28216|Betaproteobacteria,2KV97@206389|Rhodocyclales	206389|Rhodocyclales	NU	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_8
k59_454195_1	159087.Daro_3554	1.14e-69	218.0	2DBBG@1|root,2Z87Z@2|Bacteria,1R3GN@1224|Proteobacteria,2WIHF@28216|Betaproteobacteria,2KXZP@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF4239)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4239
k59_391832_1	1537917.JU82_03845	1.29e-79	239.0	COG1714@1|root,COG1714@2|Bacteria,1N7R6@1224|Proteobacteria,42U2T@68525|delta/epsilon subdivisions,2YPV6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
k59_1334356_2	1123392.AQWL01000007_gene866	1.7e-20	87.4	COG1516@1|root,COG1516@2|Bacteria,1MZ3G@1224|Proteobacteria,2VU2S@28216|Betaproteobacteria,1KT6P@119069|Hydrogenophilales	119069|Hydrogenophilales	NOU	Flagellar protein FliS	-	-	-	ko:K02422	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliS
k59_221840_1	296591.Bpro_0037	2e-18	85.1	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,2VHS3@28216|Betaproteobacteria,4A9QR@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
k59_221840_2	670307.HYPDE_33443	2.67e-105	323.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,2TRNX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	amino acid	atrC1	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2,AA_permease_C
k59_1579181_1	1132855.KB913035_gene410	1.42e-107	327.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,2VH9N@28216|Betaproteobacteria,2KKUE@206350|Nitrosomonadales	206350|Nitrosomonadales	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	-	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
k59_1579181_2	1165096.ARWF01000001_gene1397	0.000251	41.6	COG3296@1|root,COG3296@2|Bacteria,1N4ZK@1224|Proteobacteria,2VWRG@28216|Betaproteobacteria,2KN4V@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Domain of unknown function (DUF4870)	-	-	-	ko:K09940	-	-	-	-	ko00000	-	-	-	DUF4870
k59_580194_2	1537917.JU82_08705	4.04e-44	149.0	COG3267@1|root,COG3267@2|Bacteria,1QUIM@1224|Proteobacteria,42NAC@68525|delta/epsilon subdivisions,2YNHY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	ATPase (AAA	-	-	4.3.3.7	ko:K01714,ko:K12283	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	AAA_22
k59_1748795_1	748247.AZKH_1915	6e-96	292.0	28P7P@1|root,2ZC1Y@2|Bacteria,1RBDI@1224|Proteobacteria,2W4GK@28216|Betaproteobacteria	1224|Proteobacteria	S	outer membrane porin, OprD family	-	-	-	-	-	-	-	-	-	-	-	-	OprD
k59_1102134_1	709032.Sulku_0700	3.7e-86	272.0	COG1256@1|root,COG1749@1|root,COG1256@2|Bacteria,COG1749@2|Bacteria,1MV2M@1224|Proteobacteria,42PBN@68525|delta/epsilon subdivisions,2YMGR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar hook-associated protein	flgK	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k59_1102135_1	709032.Sulku_1915	1.26e-112	339.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,42M35@68525|delta/epsilon subdivisions,2YM7I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0354	DXP_synthase_N,Transket_pyr,Transketolase_C
k59_1630161_1	237609.PSAKL28_10760	1.44e-45	153.0	2C10P@1|root,32SS7@2|Bacteria,1MZZG@1224|Proteobacteria,1SBSS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_221925_1	880074.BARVI_12885	1.56e-07	57.4	COG0760@1|root,COG0760@2|Bacteria,4NGIR@976|Bacteroidetes,2FNS9@200643|Bacteroidia,22VWY@171551|Porphyromonadaceae	976|Bacteroidetes	M	peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3
k59_1687463_2	709032.Sulku_0869	5.42e-50	170.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,42MUG@68525|delta/epsilon subdivisions,2YMMM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
k59_1052220_1	1304883.KI912532_gene829	8.35e-10	59.3	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,2VKW1@28216|Betaproteobacteria,2KXN2@206389|Rhodocyclales	206389|Rhodocyclales	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
k59_701692_2	159087.Daro_3394	6e-41	135.0	COG5007@1|root,COG5007@2|Bacteria,1MZCZ@1224|Proteobacteria,2VU0K@28216|Betaproteobacteria,2KXGQ@206389|Rhodocyclales	206389|Rhodocyclales	K	BolA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	BolA
k59_583531_1	159087.Daro_4158	6.36e-64	195.0	COG3411@1|root,COG3411@2|Bacteria,1MZR4@1224|Proteobacteria,2VTY1@28216|Betaproteobacteria,2KWNM@206389|Rhodocyclales	206389|Rhodocyclales	C	ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx
k59_583531_2	159087.Daro_4159	5.43e-30	111.0	COG2945@1|root,COG2945@2|Bacteria,1MUDY@1224|Proteobacteria,2VJ8M@28216|Betaproteobacteria,2KV03@206389|Rhodocyclales	206389|Rhodocyclales	S	hydrolase of the alpha beta superfamily	-	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Hydrolase_4,Peptidase_S15
k59_1337488_1	1249480.B649_04040	1.27e-101	318.0	COG0715@1|root,COG0834@1|root,COG2199@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42MCD@68525|delta/epsilon subdivisions,2YN6K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	ET	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,NMT1,SBP_bac_3
k59_1873621_2	395494.Galf_2868	1.29e-53	189.0	COG0659@1|root,COG0664@1|root,COG0659@2|Bacteria,COG0664@2|Bacteria,1MVWV@1224|Proteobacteria,2VN25@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp,cNMP_binding
k59_396026_1	1165841.SULAR_03742	2.2e-74	249.0	COG3387@1|root,COG3387@2|Bacteria,1MXWR@1224|Proteobacteria	1224|Proteobacteria	G	phosphorylase kinase alphabeta	ygeQ	-	-	ko:K07190	ko04020,ko04910,ko04922,map04020,map04910,map04922	-	-	-	ko00000,ko00001	-	-	-	Glyco_hydro_15
k59_1514771_2	1121035.AUCH01000002_gene1471	2.5e-42	154.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,2VIB1@28216|Betaproteobacteria,2KUYS@206389|Rhodocyclales	206389|Rhodocyclales	C	nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC	napA	-	-	ko:K02567	ko00910,ko01120,map00910,map01120	M00529,M00530	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_1690558_1	1249480.B649_03050	2.12e-97	297.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,42MYT@68525|delta/epsilon subdivisions,2YMKP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	phosphate transporter	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
k59_281690_1	1165841.SULAR_05733	3.69e-125	364.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,42M8S@68525|delta/epsilon subdivisions,2YNN2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
k59_281692_1	1537917.JU82_01405	1.65e-61	197.0	COG2199@1|root,COG3706@2|Bacteria,1NC00@1224|Proteobacteria,43DI1@68525|delta/epsilon subdivisions,2YTIQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	diguanylate cyclase	-	-	2.7.7.65	ko:K13590	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF
k59_281692_2	709032.Sulku_1480	2.16e-08	54.7	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,42WJ0@68525|delta/epsilon subdivisions,2YQJR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	PFAM TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_1690567_1	159087.Daro_2459	2.4e-161	459.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,2VIEY@28216|Betaproteobacteria,2KV1Z@206389|Rhodocyclales	206389|Rhodocyclales	J	tRNA synthetases class I (W and Y)	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
k59_867277_1	709032.Sulku_1615	9.46e-71	223.0	COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,1MXYZ@1224|Proteobacteria,42M4E@68525|delta/epsilon subdivisions,2YMY0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF1722)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
k59_43814_1	159087.Daro_0459	8.7e-105	330.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,2KUIU@206389|Rhodocyclales	206389|Rhodocyclales	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1337536_1	485916.Dtox_1457	1.52e-62	214.0	COG1061@1|root,COG1502@1|root,COG4951@1|root,COG1061@2|Bacteria,COG1502@2|Bacteria,COG4951@2|Bacteria,1TS5R@1239|Firmicutes,24AWW@186801|Clostridia,262ZA@186807|Peptococcaceae	186801|Clostridia	L	Type III restriction	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,PLDc_2,ResIII
k59_1873672_1	1120999.JONM01000011_gene1638	9.25e-104	326.0	COG3391@1|root,COG3391@2|Bacteria,1PX3W@1224|Proteobacteria,2W0YQ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
k59_813981_1	159087.Daro_3909	2.16e-140	413.0	COG0557@1|root,COG0557@2|Bacteria,1NGSQ@1224|Proteobacteria,2VHMM@28216|Betaproteobacteria,2KVMW@206389|Rhodocyclales	206389|Rhodocyclales	K	RNB	-	-	3.1.13.1	ko:K01147	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNB
k59_930452_1	1165841.SULAR_09039	1.84e-127	370.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2YMY9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_224512_1	1165841.SULAR_03762	2.32e-34	129.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2YR9K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	-	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
k59_224512_2	1165841.SULAR_03767	4.18e-156	448.0	COG1085@1|root,COG1085@2|Bacteria,1MU3E@1224|Proteobacteria,42MP4@68525|delta/epsilon subdivisions,2YNIF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1085 Galactose-1-phosphate uridylyltransferase	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
k59_224512_3	944481.JAFP01000001_gene974	8.09e-11	64.3	COG1449@1|root,COG1449@2|Bacteria,1Q9WP@1224|Proteobacteria,42M42@68525|delta/epsilon subdivisions,2WM5M@28221|Deltaproteobacteria,2M6SW@213113|Desulfurellales	28221|Deltaproteobacteria	G	Domain of unknown function (DUF1926)	-	-	2.4.1.25	ko:K22451	ko00500,map00500	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH57	-	DUF1925,DUF1926,Glyco_hydro_57
k59_993639_1	1165841.SULAR_00945	5.98e-121	355.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,42MQT@68525|delta/epsilon subdivisions,2YMQ6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Belongs to the SEDS family	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
k59_930460_1	1537917.JU82_01770	1.1e-147	421.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,42NPN@68525|delta/epsilon subdivisions,2YMV8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10	ko:K00795	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364	R01658,R02003	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
k59_930460_2	1537917.JU82_01765	3.8e-50	173.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,42M80@68525|delta/epsilon subdivisions,2YMEN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
k59_638695_2	709032.Sulku_0763	1.34e-52	174.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	tolA	-	-	ko:K03646,ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1,2.C.1.2	-	-	TonB_2,TonB_C
k59_742641_1	1120925.F941_01454	3.08e-26	107.0	COG0406@1|root,COG0406@2|Bacteria,1RHAT@1224|Proteobacteria,1S69R@1236|Gammaproteobacteria,3NMN9@468|Moraxellaceae	1236|Gammaproteobacteria	G	Phosphoglycerate mutase family	cobC	-	3.1.3.73,5.4.2.12	ko:K02226,ko:K15634	ko00010,ko00260,ko00680,ko00860,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map00860,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00122	R01518,R04594,R11173	RC00017,RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
k59_742641_2	314345.SPV1_11671	4.4e-42	139.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria	1224|Proteobacteria	O	Peptidylprolyl isomerase	ppiC	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0071704,GO:0140096,GO:1901564	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3
k59_1806958_1	709032.Sulku_2283	3.35e-62	196.0	COG0526@1|root,COG0526@2|Bacteria,1QZ1W@1224|Proteobacteria,43CE3@68525|delta/epsilon subdivisions,2YTBP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CO	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin
k59_281776_1	1132855.KB913035_gene1293	2.09e-120	357.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,2KM0R@206350|Nitrosomonadales	206350|Nitrosomonadales	L	Belongs to the DEAD box helicase family	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
k59_224525_1	1122604.JONR01000008_gene2254	2.8e-21	98.6	COG0469@1|root,COG0469@2|Bacteria,1NNNX@1224|Proteobacteria,1RYF5@1236|Gammaproteobacteria,1X9M9@135614|Xanthomonadales	135614|Xanthomonadales	G	Pyruvate kinase, barrel domain	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK
k59_701848_1	1121035.AUCH01000023_gene3442	3.77e-169	491.0	COG2199@1|root,COG3706@2|Bacteria,1NECV@1224|Proteobacteria,2VPI9@28216|Betaproteobacteria,2KXT9@206389|Rhodocyclales	206389|Rhodocyclales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_930490_1	1249480.B649_06380	7.52e-102	296.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,42RJQ@68525|delta/epsilon subdivisions,2YP4R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
k59_930490_2	709032.Sulku_1235	1.01e-08	54.3	COG0125@1|root,COG0125@2|Bacteria,1R98D@1224|Proteobacteria,43B5Z@68525|delta/epsilon subdivisions,2YP5N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
k59_520320_2	1537917.JU82_03440	1.59e-42	150.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,42NYV@68525|delta/epsilon subdivisions,2YN1D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	pyridine nucleotide-disulfide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_43880_1	666681.M301_1970	1.1e-37	136.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,2VH91@28216|Betaproteobacteria,2KKUC@206350|Nitrosomonadales	206350|Nitrosomonadales	E	Beta-eliminating lyase	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
k59_43880_2	666681.M301_1971	9.06e-143	412.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,2VH91@28216|Betaproteobacteria,2KM7T@206350|Nitrosomonadales	206350|Nitrosomonadales	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
k59_867336_1	1121106.JQKB01000006_gene1318	3.16e-86	272.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,2TQK5@28211|Alphaproteobacteria,2JSIF@204441|Rhodospirillales	204441|Rhodospirillales	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_7,Fer4_9,Pyr_redox_2,Pyr_redox_3
k59_1397766_2	709032.Sulku_0563	6.14e-51	170.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,42MDN@68525|delta/epsilon subdivisions,2YMPS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k59_43882_1	1123518.ARWI01000001_gene607	1.24e-62	200.0	COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,1RNTF@1236|Gammaproteobacteria,4625T@72273|Thiotrichales	72273|Thiotrichales	N	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
k59_930507_1	1537917.JU82_11440	1.34e-44	147.0	2AJ62@1|root,319QQ@2|Bacteria,1Q3M5@1224|Proteobacteria,42XHG@68525|delta/epsilon subdivisions,2YQWM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_335103_1	1249480.B649_09950	6.79e-103	309.0	COG0662@1|root,COG0836@1|root,COG0662@2|Bacteria,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,42MDP@68525|delta/epsilon subdivisions,2YMW3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	GM	Belongs to the mannose-6-phosphate isomerase type 2 family	manC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
k59_224545_1	1268622.AVS7_00818	1.24e-68	226.0	COG0845@1|root,COG0845@2|Bacteria,1MW65@1224|Proteobacteria,2VHQP@28216|Betaproteobacteria,4AA19@80864|Comamonadaceae	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	mdtA	-	-	ko:K07799	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_930535_1	317025.Tcr_0094	1.5e-103	313.0	COG2223@1|root,COG2223@2|Bacteria,1QVX0@1224|Proteobacteria,1T2MB@1236|Gammaproteobacteria,461YK@72273|Thiotrichales	72273|Thiotrichales	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_867364_1	1537917.JU82_10960	1.34e-113	333.0	COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,42MXH@68525|delta/epsilon subdivisions,2YMN3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	4-hydroxybenzoate	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
k59_396236_2	709032.Sulku_0250	5.86e-59	190.0	COG1672@1|root,COG1672@2|Bacteria,1PMVJ@1224|Proteobacteria,42PCP@68525|delta/epsilon subdivisions,2YNZF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM Archaea bacterial proteins of	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	DUF234
k59_742727_1	1249480.B649_00595	5.5e-85	275.0	COG0715@1|root,COG0834@1|root,COG4191@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PNA@68525|delta/epsilon subdivisions,2YTBI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EPT	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,NMT1,SBP_bac_3
k59_701928_1	395494.Galf_0174	1.93e-48	171.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,2VHUY@28216|Betaproteobacteria,44VD7@713636|Nitrosomonadales	28216|Betaproteobacteria	E	glutamate synthase alpha subunit domain protein	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_1476908_1	1165841.SULAR_08532	6.45e-78	245.0	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,42MBB@68525|delta/epsilon subdivisions,2YMFZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
k59_771000_1	1026882.MAMP_01030	5.75e-32	132.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,1RMW6@1236|Gammaproteobacteria,45ZUT@72273|Thiotrichales	72273|Thiotrichales	S	DNA internalization-related competence protein ComEC Rec2	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
k59_889594_1	929558.SMGD1_1397	1.93e-27	108.0	2AXCU@1|root,31PC5@2|Bacteria,1QM2E@1224|Proteobacteria,42SSQ@68525|delta/epsilon subdivisions,2YPP6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Beta-ketoacyl synthase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_2
k59_889594_2	1122182.KB903825_gene763	2e-10	62.4	COG0304@1|root,COG0304@2|Bacteria,2GIY4@201174|Actinobacteria,4DAP8@85008|Micromonosporales	201174|Actinobacteria	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_10172_1	395495.Lcho_3586	4.54e-07	50.4	COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,2VH0T@28216|Betaproteobacteria,1KJNT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	dienelactone hydrolase	clcD	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
k59_10172_2	159087.Daro_1853	4.79e-64	199.0	2C8DW@1|root,32RKY@2|Bacteria,1MZUD@1224|Proteobacteria,2VUU8@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF3597)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3597
k59_949272_1	709032.Sulku_1913	6.37e-44	162.0	COG0745@1|root,COG3437@1|root,COG3829@1|root,COG0745@2|Bacteria,COG3437@2|Bacteria,COG3829@2|Bacteria,1NWAF@1224|Proteobacteria,43DAK@68525|delta/epsilon subdivisions,2YTHP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,Response_reg
k59_1711325_1	1249480.B649_11390	1.8e-45	162.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2YMW5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,TarH,dCache_2,sCache_2
k59_1183117_1	395494.Galf_1210	1.25e-161	470.0	COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,2VH9I@28216|Betaproteobacteria,44W5Y@713636|Nitrosomonadales	28216|Betaproteobacteria	P	K+ potassium transporter	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
k59_1008153_1	1537917.JU82_06445	1.41e-36	132.0	COG1868@1|root,COG1868@2|Bacteria,1MX01@1224|Proteobacteria,42N2Y@68525|delta/epsilon subdivisions,2YMHG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar motor switch protein	fliM	-	-	ko:K02416	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliM,FliMN_C
k59_1008153_2	1537917.JU82_06440	3.41e-68	214.0	COG1886@1|root,COG1886@2|Bacteria,1NF4E@1224|Proteobacteria,42R4G@68525|delta/epsilon subdivisions,2YN6N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar motor switch protein	fliY	-	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FliMN_C
k59_184052_1	265072.Mfla_1851	7.48e-71	228.0	COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,2VHJ8@28216|Betaproteobacteria,2KKG7@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA	rlmD	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	tRNA_U5-meth_tr
k59_1711337_1	748247.AZKH_p0519	4.57e-101	317.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,2VJ61@28216|Betaproteobacteria,2KXRI@206389|Rhodocyclales	206389|Rhodocyclales	S	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_1536689_1	1410653.JHVC01000011_gene877	7.07e-58	187.0	COG1145@1|root,COG1145@2|Bacteria,1TPAZ@1239|Firmicutes,249NJ@186801|Clostridia,36F9G@31979|Clostridiaceae	186801|Clostridia	C	binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6
k59_360390_1	709032.Sulku_0329	2.35e-225	631.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,43BKD@68525|delta/epsilon subdivisions,2YNJC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_360390_2	709032.Sulku_1447	1.01e-26	107.0	COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,42KZP@68525|delta/epsilon subdivisions,2YMBP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG1055 Na H antiporter NhaD and related arsenite	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
k59_1418625_1	765913.ThidrDRAFT_3310	6.05e-06	52.4	COG0318@1|root,COG0318@2|Bacteria,1MXPB@1224|Proteobacteria,1RRD5@1236|Gammaproteobacteria,1WW42@135613|Chromatiales	135613|Chromatiales	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
k59_1418625_3	1453503.AU05_08455	1.56e-91	281.0	COG0716@1|root,COG0716@2|Bacteria,1N2QA@1224|Proteobacteria,1RQ9B@1236|Gammaproteobacteria,1YFQB@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	C	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_127307_2	709032.Sulku_2649	2.54e-18	84.3	COG1538@1|root,COG1538@2|Bacteria,1QWWG@1224|Proteobacteria,42PH5@68525|delta/epsilon subdivisions,2YMHH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_771058_1	709032.Sulku_1309	4.18e-114	338.0	COG0517@1|root,COG2199@1|root,COG0517@2|Bacteria,COG2199@2|Bacteria,1RGCV@1224|Proteobacteria,43DAF@68525|delta/epsilon subdivisions,2YTHJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG2199 FOG GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GGDEF
k59_771058_2	709032.Sulku_1310	4.88e-21	91.7	COG1956@1|root,COG3604@1|root,COG1956@2|Bacteria,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,42Y69@68525|delta/epsilon subdivisions,2YNEN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	Transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF_2,HTH_8,Sigma54_activat
k59_1065616_1	1500893.JQNB01000001_gene2056	8.8e-62	211.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMDS@1236|Gammaproteobacteria,1X37S@135614|Xanthomonadales	135614|Xanthomonadales	J	Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs	rne	-	3.1.26.12	ko:K08300	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
k59_360407_1	305900.GV64_07030	2.41e-58	191.0	COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,1RP2Y@1236|Gammaproteobacteria,1XID6@135619|Oceanospirillales	135619|Oceanospirillales	T	Phosphate starvation-inducible protein PhoH	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
k59_539221_1	748658.KB907313_gene2401	1.84e-56	198.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WZVH@135613|Chromatiales	135613|Chromatiales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_539222_1	709032.Sulku_1985	1.66e-123	356.0	COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,42MES@68525|delta/epsilon subdivisions,2YMU9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
k59_949340_1	929558.SMGD1_2325	3.79e-90	280.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,42MAP@68525|delta/epsilon subdivisions,2YNFF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	transporter	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
k59_831617_1	1249480.B649_08130	3.35e-172	500.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42UBD@68525|delta/epsilon subdivisions,2YRGP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	7TM diverse intracellular signalling	-	-	-	ko:K20971	ko02025,map02025	-	-	-	ko00000,ko00001,ko01001,ko02022	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c
k59_419755_1	1304883.KI912532_gene2010	1.23e-109	331.0	COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,2VIYX@28216|Betaproteobacteria,2KU69@206389|Rhodocyclales	206389|Rhodocyclales	C	Sulfite reductase	cysI	-	1.8.1.2	ko:K00381	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
k59_1125519_1	160488.PP_2270	4e-96	300.0	COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1QWI1@1224|Proteobacteria,1RZ7K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Toprim-like	-	-	3.6.4.12	ko:K17680	-	-	-	-	ko00000,ko01000,ko03029	-	-	-	AAA_25,DnaB_C,Toprim_2
k59_1536755_1	159087.Daro_4103	1.39e-48	170.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,2VIGG@28216|Betaproteobacteria,2KUAA@206389|Rhodocyclales	206389|Rhodocyclales	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
k59_1536755_2	159087.Daro_4104	9.4e-28	105.0	COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,2VR3B@28216|Betaproteobacteria,2KWCK@206389|Rhodocyclales	206389|Rhodocyclales	J	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA	gidB	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
k59_1477028_1	1165841.SULAR_08572	2.44e-05	46.2	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,42NFK@68525|delta/epsilon subdivisions,2YNST@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_1477028_2	1165841.SULAR_08577	1.52e-69	216.0	COG0746@1|root,COG0746@2|Bacteria,1NEIC@1224|Proteobacteria,42SCE@68525|delta/epsilon subdivisions,2YPMS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
k59_10250_1	948106.AWZT01000035_gene2440	3.88e-64	219.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,2VHDH@28216|Betaproteobacteria,1K0RR@119060|Burkholderiaceae	28216|Betaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k59_1418713_1	1165841.SULAR_02753	2.42e-51	170.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,42M2J@68525|delta/epsilon subdivisions,2YN8F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	frdB	-	1.3.5.1,1.3.5.4	ko:K00240,ko:K00245	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0191	Fer2_3,Fer4_8
k59_1418713_2	1165841.SULAR_02748	1.74e-51	176.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,42M81@68525|delta/epsilon subdivisions,2YMTF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_1418717_1	998088.B565_1399	1.36e-32	115.0	COG3169@1|root,COG3169@2|Bacteria,1RHBQ@1224|Proteobacteria,1S7UR@1236|Gammaproteobacteria,1Y4GF@135624|Aeromonadales	135624|Aeromonadales	S	Putative member of DMT superfamily (DUF486)	-	-	-	ko:K09922	-	-	-	-	ko00000	-	-	-	DMT_6
k59_360470_1	1537917.JU82_09710	1.99e-42	144.0	COG3381@1|root,COG3381@2|Bacteria,1N4MX@1224|Proteobacteria,42RVB@68525|delta/epsilon subdivisions,2YP5X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	component of anaerobic	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_del
k59_1594233_1	1120948.KB903247_gene4452	1.51e-06	54.7	COG1309@1|root,COG1309@2|Bacteria,2GP2Z@201174|Actinobacteria,4E6W0@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
k59_10283_1	159087.Daro_4119	1.27e-93	288.0	2A8Z1@1|root,30Y2U@2|Bacteria,1PJYG@1224|Proteobacteria,2VJ83@28216|Betaproteobacteria,2KVGT@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1300163_1	997884.HMPREF1068_00147	1.5e-27	110.0	COG1216@1|root,COG1216@2|Bacteria,4NJ6R@976|Bacteroidetes,2FN12@200643|Bacteroidia,4AMT5@815|Bacteroidaceae	976|Bacteroidetes	S	Glycosyltransferase, group 2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_1422337_2	1537917.JU82_05215	5.24e-27	108.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,42MHD@68525|delta/epsilon subdivisions,2YN9P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
k59_303690_1	471223.GWCH70_1766	7.45e-66	213.0	COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4HB0P@91061|Bacilli,1WH7X@129337|Geobacillus	91061|Bacilli	L	MULE transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
k59_422513_1	1304883.KI912532_gene2356	6.14e-94	285.0	COG0477@1|root,COG2814@2|Bacteria,1QTWR@1224|Proteobacteria,2VIC5@28216|Betaproteobacteria,2KU64@206389|Rhodocyclales	206389|Rhodocyclales	EGP	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_483214_1	1249480.B649_04190	8.65e-100	296.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,42NCJ@68525|delta/epsilon subdivisions,2YMQJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
k59_186989_1	765913.ThidrDRAFT_1229	1.48e-50	168.0	COG1776@1|root,COG1776@2|Bacteria,1R430@1224|Proteobacteria,1SBPR@1236|Gammaproteobacteria,1WY4R@135613|Chromatiales	135613|Chromatiales	NT	CheC, inhibitor of MCP methylation	-	-	-	ko:K03410	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheC,CheX
k59_1714302_1	1123326.JFBL01000007_gene619	9.22e-24	100.0	COG2986@1|root,COG2986@2|Bacteria,1MU6K@1224|Proteobacteria,42MST@68525|delta/epsilon subdivisions,2YNF3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Aromatic amino acid lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
k59_1714302_2	1134474.O59_000024	0.000387	44.7	COG1216@1|root,COG1216@2|Bacteria,1QVEM@1224|Proteobacteria,1T2CN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Glycosyl Transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_1186014_1	1249480.B649_07380	1.34e-98	307.0	COG5001@1|root,COG5001@2|Bacteria,1QV5H@1224|Proteobacteria,42PV8@68525|delta/epsilon subdivisions,2YMZX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,LapD_MoxY_N
k59_952616_1	1249480.B649_05950	4.77e-93	278.0	COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,42PQF@68525|delta/epsilon subdivisions,2YMTU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
k59_1069170_1	159087.Daro_3363	1.4e-132	380.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,2VH1U@28216|Betaproteobacteria,2KUAR@206389|Rhodocyclales	206389|Rhodocyclales	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
k59_1361603_1	1165841.SULAR_08477	2.94e-92	271.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,42QPX@68525|delta/epsilon subdivisions,2YNW3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
k59_187008_1	709032.Sulku_2451	3.74e-95	291.0	COG0517@1|root,COG2199@1|root,COG0517@2|Bacteria,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42SZE@68525|delta/epsilon subdivisions,2YR4N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GGDEF
k59_1302425_1	598659.NAMH_0767	4.09e-55	188.0	COG3174@1|root,COG3174@2|Bacteria,1RA19@1224|Proteobacteria,42PB8@68525|delta/epsilon subdivisions,2YNQN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function (DUF4010)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010
k59_130863_1	326298.Suden_0647	3.71e-60	194.0	2C2AA@1|root,2ZAYY@2|Bacteria,1RD8I@1224|Proteobacteria,42N13@68525|delta/epsilon subdivisions,2YN8K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	TraT complement resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	TraT
k59_1540395_1	709032.Sulku_1319	2.53e-75	231.0	COG2078@1|root,COG2078@2|Bacteria,1RJP4@1224|Proteobacteria,42SBG@68525|delta/epsilon subdivisions,2YP68@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM AMMECR1 domain protein	-	-	-	ko:K09141	-	-	-	-	ko00000	-	-	-	AMMECR1
k59_1540395_2	1537917.JU82_01220	3.73e-71	222.0	COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,42R55@68525|delta/epsilon subdivisions,2YNS0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
k59_660102_1	1165841.SULAR_08337	1.3e-16	74.7	29D34@1|root,30016@2|Bacteria,1Q5ZK@1224|Proteobacteria,43250@68525|delta/epsilon subdivisions,2YSH9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_952664_1	563040.Saut_1372	7.8e-44	152.0	COG0845@1|root,COG0845@2|Bacteria,1QZ27@1224|Proteobacteria,43CEE@68525|delta/epsilon subdivisions,2YTBZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1186057_1	1537917.JU82_09120	9.04e-157	470.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,42MGK@68525|delta/epsilon subdivisions,2YMHU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_483317_2	159087.Daro_3797	1.98e-39	132.0	2C44J@1|root,331D7@2|Bacteria,1N8VR@1224|Proteobacteria,2WIHH@28216|Betaproteobacteria,2KX6N@206389|Rhodocyclales	206389|Rhodocyclales	C	Phenol hydroxylase subunit	-	-	-	ko:K16249	ko00361,ko00362,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00623,map01100,map01120,map01220	M00548	R03560,R03608,R10042,R10043	RC00046,RC00490	ko00000,ko00001,ko00002	-	-	-	Phenol_hyd_sub
k59_483317_3	159087.Daro_3798	1.68e-61	204.0	COG1719@1|root,COG3829@1|root,COG1719@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,2VIKD@28216|Betaproteobacteria,2KUEW@206389|Rhodocyclales	206389|Rhodocyclales	K	Fis family transcriptional regulator	poxR	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat,V4R,XylR_N
k59_1540430_1	1537917.JU82_05955	7.14e-33	126.0	COG2982@1|root,COG2982@2|Bacteria,1QA6E@1224|Proteobacteria,42NCN@68525|delta/epsilon subdivisions,2YM89@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_1,DUF3971
k59_1714364_1	1537917.JU82_06965	7.14e-25	96.7	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,42RVM@68525|delta/epsilon subdivisions,2YT8U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
k59_1714364_2	1537917.JU82_06960	1.14e-75	237.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2YMC1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_303793_1	1005999.GLGR_0272	4.89e-117	351.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPN9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	ybiT	GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0050896	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
k59_599722_1	583345.Mmol_0049	3.9e-116	352.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2VH3Q@28216|Betaproteobacteria,2KKSN@206350|Nitrosomonadales	206350|Nitrosomonadales	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
k59_542997_1	1249480.B649_07690	7.56e-125	361.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,42MB0@68525|delta/epsilon subdivisions,2YMC0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
k59_599744_1	709032.Sulku_2546	8.47e-09	55.8	COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,42P71@68525|delta/epsilon subdivisions,2YNAA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Phospholipid glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5,Acyltransferase
k59_69164_2	159087.Daro_3000	3.71e-84	263.0	COG1807@1|root,COG1807@2|Bacteria,1PUE3@1224|Proteobacteria,2VHPU@28216|Betaproteobacteria,2KUEG@206389|Rhodocyclales	206389|Rhodocyclales	M	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
k59_774032_1	159087.Daro_3872	2.89e-168	497.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
k59_363312_1	748247.AZKH_1315	6.17e-54	185.0	COG1256@1|root,COG1256@2|Bacteria,1MV2M@1224|Proteobacteria,2VH02@28216|Betaproteobacteria,2KVUK@206389|Rhodocyclales	206389|Rhodocyclales	N	Belongs to the flagella basal body rod proteins family	flgK	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k59_660178_1	159087.Daro_0860	1.04e-75	237.0	COG0477@1|root,COG2814@2|Bacteria,1MVZI@1224|Proteobacteria,2VHWT@28216|Betaproteobacteria,2KV5D@206389|Rhodocyclales	206389|Rhodocyclales	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1_like
k59_660178_2	85643.Tmz1t_3071	4.83e-71	226.0	COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,2VHSH@28216|Betaproteobacteria,2KVD8@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
k59_1597162_1	458817.Shal_2271	2.42e-37	129.0	COG0375@1|root,COG0375@2|Bacteria,1MZJH@1224|Proteobacteria,1SXX2@1236|Gammaproteobacteria,2QCNN@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
k59_1597162_2	1165841.SULAR_02893	5.6e-59	192.0	COG0309@1|root,COG0309@2|Bacteria,1MVCC@1224|Proteobacteria,42M3M@68525|delta/epsilon subdivisions,2YMY3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	hydrogenase expression formation protein	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
k59_422659_1	1122194.AUHU01000003_gene2338	1.32e-08	57.4	COG2199@1|root,COG3706@2|Bacteria,1MX83@1224|Proteobacteria,1RR0S@1236|Gammaproteobacteria,467NC@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_3
k59_422659_3	349520.PPE_02228	1.06e-09	58.9	COG4705@1|root,COG4705@2|Bacteria,1VU8X@1239|Firmicutes,4HUPQ@91061|Bacilli,26XVF@186822|Paenibacillaceae	91061|Bacilli	S	Repeat of Unknown Function (DUF347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF347
k59_599771_1	1537917.JU82_07105	1.97e-108	323.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,42M7H@68525|delta/epsilon subdivisions,2YMPK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
k59_835064_1	159087.Daro_3850	3.8e-119	346.0	COG0631@1|root,COG0631@2|Bacteria,1MVE7@1224|Proteobacteria,2VIAV@28216|Betaproteobacteria,2KUHY@206389|Rhodocyclales	206389|Rhodocyclales	T	COG0631 Serine threonine protein phosphatase	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
k59_69188_1	1175306.GWL_02230	4.81e-67	229.0	COG1629@1|root,COG4771@2|Bacteria,1MW7D@1224|Proteobacteria,2VIV2@28216|Betaproteobacteria,4766D@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_1480398_1	159087.Daro_4045	7.08e-118	346.0	COG4177@1|root,COG4177@2|Bacteria,1MUPI@1224|Proteobacteria,2VJQX@28216|Betaproteobacteria,2KW2U@206389|Rhodocyclales	206389|Rhodocyclales	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_1730668_1	1165841.SULAR_03477	1.66e-87	281.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,42MW3@68525|delta/epsilon subdivisions,2YMT6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
k59_1034534_1	1121935.AQXX01000101_gene677	2.3e-38	136.0	COG4278@1|root,COG4278@2|Bacteria,1RBTS@1224|Proteobacteria,1S5B5@1236|Gammaproteobacteria,1XJGE@135619|Oceanospirillales	135619|Oceanospirillales	H	phenylacetate-CoA ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_148777_1	1249480.B649_01845	1.8e-93	284.0	COG2199@1|root,COG3706@2|Bacteria,1MWHH@1224|Proteobacteria,42RQ2@68525|delta/epsilon subdivisions,2YP69@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG2199 FOG GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,GGDEF
k59_1788753_1	1132855.KB913035_gene1379	7.54e-70	226.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,2VH45@28216|Betaproteobacteria,2KM4W@206350|Nitrosomonadales	206350|Nitrosomonadales	P	STAS domain	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k59_1672092_1	326298.Suden_1927	9.23e-55	192.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GAF,HATPase_c,HisKA,PAS_3,PAS_7,PAS_9,Response_reg
k59_1788761_1	1537917.JU82_02080	3.32e-58	202.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,42NKH@68525|delta/epsilon subdivisions,2YMVS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the helicase family. UvrD subfamily	addA	-	3.1.11.5	ko:K03582	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C
k59_1201537_1	709032.Sulku_1256	1.32e-149	431.0	COG1055@1|root,COG1055@2|Bacteria,1MUX4@1224|Proteobacteria,42MHN@68525|delta/epsilon subdivisions,2YMYK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Involved in arsenical resistance. Thought to form the channel of an arsenite pump	arsB	-	-	ko:K03893	-	-	-	-	ko00000,ko02000	2.A.45.1,3.A.4.1	-	-	ArsB
k59_316868_2	1247024.JRLH01000006_gene2700	2.08e-08	60.5	COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MWDY@1224|Proteobacteria,1RRXF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1	aas	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0008779,GO:0008922,GO:0009058,GO:0009987,GO:0015645,GO:0016020,GO:0016021,GO:0016740,GO:0016746,GO:0016747,GO:0016874,GO:0016877,GO:0016878,GO:0019637,GO:0019752,GO:0031224,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044425,GO:0044464,GO:0071704,GO:0071944,GO:0090407,GO:1901576	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	iEC042_1314.EC042_3034	AMP-binding,AMP-binding_C,Acyltransferase
k59_1201564_1	159087.Daro_3990	7.92e-73	247.0	COG0517@1|root,COG2203@1|root,COG3829@1|root,COG5001@1|root,COG0517@2|Bacteria,COG2203@2|Bacteria,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KUCK@206389|Rhodocyclales	206389|Rhodocyclales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CZB,EAL,GAF_2,GGDEF,PAS_4,PAS_9
k59_1034615_1	1249480.B649_06425	1.2e-80	263.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2YRKW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0474 Cation transport ATPase	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
k59_501872_2	288000.BBta_1555	2.39e-43	147.0	COG1321@1|root,COG1321@2|Bacteria,1RH2Z@1224|Proteobacteria,2UA3F@28211|Alphaproteobacteria,3JZ7Q@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Helix-turn-helix diphteria tox regulatory element	mntR	-	-	ko:K11924	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress
k59_1560702_1	387093.SUN_0421	6.8e-121	350.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,42N0M@68525|delta/epsilon subdivisions,2YT9X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules	xerH	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_1316389_1	1298593.TOL_0790	3.69e-49	164.0	COG4705@1|root,COG4705@2|Bacteria,1MVMJ@1224|Proteobacteria,1S35X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	membrane-anchored protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF347
k59_1201571_1	1380391.JIAS01000013_gene3785	1.01e-05	48.5	COG0683@1|root,COG0683@2|Bacteria,1MVBG@1224|Proteobacteria,2TUFA@28211|Alphaproteobacteria,2JY30@204441|Rhodospirillales	204441|Rhodospirillales	E	Periplasmic binding protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
k59_1854234_1	709032.Sulku_0934	2.23e-167	473.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,42M46@68525|delta/epsilon subdivisions,2YMYR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
k59_1148625_1	1223521.BBJX01000004_gene2294	2.04e-80	248.0	COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,2VMR0@28216|Betaproteobacteria,4AJ4U@80864|Comamonadaceae	28216|Betaproteobacteria	S	NMT1-like family	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
k59_262926_1	1249480.B649_01265	5.65e-36	129.0	COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,42MA4@68525|delta/epsilon subdivisions,2YM9Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901576	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_82845_1	1249480.B649_05085	2.56e-63	213.0	COG1344@1|root,COG1344@2|Bacteria,1N1QF@1224|Proteobacteria,42PDD@68525|delta/epsilon subdivisions,2YMYD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	flgL	-	-	ko:K02397	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
k59_438680_1	929558.SMGD1_2679	1.98e-76	247.0	COG0726@1|root,COG1649@1|root,COG0726@2|Bacteria,COG1649@2|Bacteria,1MWR2@1224|Proteobacteria,43AG1@68525|delta/epsilon subdivisions,2YT1V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Hypothetical glycosyl hydrolase family 13	-	-	-	ko:K11931	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000	-	-	-	GHL13,Polysacc_deac_1
k59_82846_1	1165841.SULAR_08719	4.99e-164	469.0	COG0045@1|root,COG0045@2|Bacteria,1PYM0@1224|Proteobacteria,42YXJ@68525|delta/epsilon subdivisions,2YR3Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	ATP citrate lyase citrate-binding	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_2,Citrate_bind
k59_725939_1	1304883.KI912532_gene20	6.44e-94	284.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,2VHEC@28216|Betaproteobacteria,2KUP4@206389|Rhodocyclales	206389|Rhodocyclales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
k59_1560743_1	472759.Nhal_2856	2.21e-91	279.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,1RNJ1@1236|Gammaproteobacteria,1WW7F@135613|Chromatiales	135613|Chromatiales	EP	PFAM Binding-protein-dependent transport	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
k59_1560743_2	1121406.JAEX01000009_gene2600	1.97e-22	97.8	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,42MFP@68525|delta/epsilon subdivisions,2WJ47@28221|Deltaproteobacteria,2M8HR@213115|Desulfovibrionales	28221|Deltaproteobacteria	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
k59_1201603_1	159087.Daro_1390	1.07e-126	367.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,2VHGK@28216|Betaproteobacteria,2KV6V@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
k59_850750_2	709032.Sulku_0486	3.89e-91	271.0	COG2860@1|root,COG2860@2|Bacteria,1RHQN@1224|Proteobacteria,42R47@68525|delta/epsilon subdivisions,2YP8Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	UPF0126
k59_1443262_1	1249480.B649_08980	3.23e-117	340.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,42NTG@68525|delta/epsilon subdivisions,2YNB7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	abc transporter atp-binding protein	iamA	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
k59_1443262_2	1537917.JU82_03505	1.85e-18	83.2	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,42MG3@68525|delta/epsilon subdivisions,2YMCB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	ABC-type transport system involved in resistance to organic solvents permease component	iamB	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE,STAS,STAS_2
k59_1495638_1	1304883.KI912532_gene3180	3.89e-98	291.0	COG0664@1|root,COG0664@2|Bacteria,1R5P7@1224|Proteobacteria,2VIQI@28216|Betaproteobacteria,2KVHP@206389|Rhodocyclales	206389|Rhodocyclales	K	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
k59_377754_1	1249480.B649_07630	8.24e-135	409.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2YN6Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DNA mismatch repair MutS family	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_III,MutS_V
k59_1267735_1	1120999.JONM01000001_gene1128	1.35e-08	55.5	COG0451@1|root,COG0451@2|Bacteria,1MVE4@1224|Proteobacteria,2VH69@28216|Betaproteobacteria,2KQFM@206351|Neisseriales	206351|Neisseriales	GM	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose	rfaD	-	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase
k59_1267735_2	395494.Galf_0627	1.51e-38	134.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,2VKFG@28216|Betaproteobacteria,44VP1@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
k59_1316471_1	1165841.SULAR_05568	1.19e-67	216.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,42N2A@68525|delta/epsilon subdivisions,2YMD3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
k59_1316471_2	387093.SUN_1745	1.17e-17	82.4	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,42M6W@68525|delta/epsilon subdivisions,2YN2C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	spoT	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT,HD_4,RelA_SpoT,TGS
k59_680624_1	1249480.B649_11495	9.44e-56	181.0	28M05@1|root,2ZAF9@2|Bacteria,1MY5U@1224|Proteobacteria,42QPW@68525|delta/epsilon subdivisions,2YP0Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	General glycosylation pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1730833_1	273121.WS0448	4.23e-05	49.7	2AIIS@1|root,3190V@2|Bacteria,1Q1CZ@1224|Proteobacteria,42TB4@68525|delta/epsilon subdivisions,2YPN5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1672259_1	395494.Galf_1102	1.56e-76	247.0	COG2199@1|root,COG3706@2|Bacteria,1MXAW@1224|Proteobacteria,2VK79@28216|Betaproteobacteria,44UZ9@713636|Nitrosomonadales	28216|Betaproteobacteria	T	diguanylate cyclase	-	-	2.7.7.65	ko:K13590	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF
k59_501984_1	563040.Saut_0706	3.14e-36	137.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,42MSB@68525|delta/epsilon subdivisions,2YMBS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
k59_438777_1	387093.SUN_2191	1.26e-109	329.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,42N6C@68525|delta/epsilon subdivisions,2YMY6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
k59_563831_1	1537917.JU82_09970	4.14e-138	400.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,42MQ3@68525|delta/epsilon subdivisions,2YMPC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
k59_1151310_1	1249480.B649_10320	2.67e-121	353.0	COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,42M3V@68525|delta/epsilon subdivisions,2YMJP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0625	GcpE
k59_380141_1	1249480.B649_09215	6.12e-84	253.0	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,42QRC@68525|delta/epsilon subdivisions,2YNZB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
k59_1204388_1	709032.Sulku_2050	2.33e-90	269.0	COG1969@1|root,COG1969@2|Bacteria,1MU87@1224|Proteobacteria,42NQ3@68525|delta/epsilon subdivisions,2YMRF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Ni Fe-hydrogenase, b-type cytochrome subunit	-	-	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
k59_566972_1	395494.Galf_0025	1.21e-85	256.0	29CX4@1|root,2ZZV8@2|Bacteria,1RFY7@1224|Proteobacteria,2VR98@28216|Betaproteobacteria,44VWB@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Domain of unknown function (DUF4390)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4390
k59_1791302_1	1304883.KI912532_gene186	2.32e-81	244.0	COG1051@1|root,COG1051@2|Bacteria,1REBW@1224|Proteobacteria,2VQ39@28216|Betaproteobacteria,2KW7A@206389|Rhodocyclales	206389|Rhodocyclales	F	Nudix N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Nudix_N_2
k59_1674616_1	1562701.BBOF01000018_gene416	7.33e-85	261.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,2VJ5H@28216|Betaproteobacteria,1K2CZ@119060|Burkholderiaceae	28216|Betaproteobacteria	L	transposase IS116 IS110 IS902 family	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_504655_1	1537917.JU82_01985	4.93e-99	298.0	COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2YMD8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	porA	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
k59_1615637_1	709032.Sulku_0460	2.09e-27	110.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,42M5Q@68525|delta/epsilon subdivisions,2YM9V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
k59_1615637_2	1537917.JU82_06745	2.02e-26	103.0	COG0083@1|root,COG0083@2|Bacteria,1MW8I@1224|Proteobacteria,42M9H@68525|delta/epsilon subdivisions,2YMZ3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
k59_852928_1	709032.Sulku_0296	4.04e-56	186.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,42MQ3@68525|delta/epsilon subdivisions,2YMPC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
k59_852928_2	709032.Sulku_0297	1.51e-72	223.0	COG2121@1|root,COG2121@2|Bacteria,1MZID@1224|Proteobacteria,42RJM@68525|delta/epsilon subdivisions,2YP5P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
k59_1318713_1	709032.Sulku_1184	3.28e-74	237.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2YNK5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DEAD box helicase family	dbpA	-	3.6.4.13	ko:K05591	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DEAD,DbpA,Helicase_C
k59_1038273_2	709032.Sulku_0594	8.38e-43	146.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,42N10@68525|delta/epsilon subdivisions,2YMIF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	LU	DNA processing protein	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
k59_318783_1	1537917.JU82_03170	2.17e-08	54.7	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,42M6T@68525|delta/epsilon subdivisions,2YMJD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
k59_621499_1	1249480.B649_10215	3.43e-68	208.0	COG0537@1|root,COG0537@2|Bacteria,1MZVD@1224|Proteobacteria,42TMC@68525|delta/epsilon subdivisions,2YPSJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	FG	(HIT) family	-	-	-	-	-	-	-	-	-	-	-	-	HIT
k59_1038286_1	1537917.JU82_06975	6.88e-63	202.0	COG0795@1|root,COG0795@2|Bacteria,1PXEK@1224|Proteobacteria,42MVG@68525|delta/epsilon subdivisions,2YN6F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	permease	-	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_1038286_2	709032.Sulku_1924	3.06e-107	311.0	COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,42RGU@68525|delta/epsilon subdivisions,2YP7I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
k59_1038286_3	1537917.JU82_06965	1.07e-99	291.0	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,42RVM@68525|delta/epsilon subdivisions,2YT8U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
k59_683824_1	1249480.B649_07385	2.17e-97	288.0	COG3672@1|root,COG3672@2|Bacteria,1RDQS@1224|Proteobacteria,42QWJ@68525|delta/epsilon subdivisions,2YNVX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Bacterial transglutaminase-like cysteine proteinase BTLCP	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C93
k59_683824_2	1121091.AUMP01000054_gene3367	1.92e-05	43.5	2DREZ@1|root,33BFB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_318801_1	1537917.JU82_08515	6.44e-86	271.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,43BJ8@68525|delta/epsilon subdivisions,2YMMJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	penicillin-binding protein	pbpA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
k59_318801_2	1537917.JU82_08510	8.78e-16	74.3	COG1123@1|root,COG1123@2|Bacteria,1QXRI@1224|Proteobacteria,43CKN@68525|delta/epsilon subdivisions,2YTDT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Abc transporter	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran
k59_27957_1	1249480.B649_03845	3.32e-97	296.0	COG2199@1|root,COG3706@2|Bacteria,1MVCZ@1224|Proteobacteria,42Z6I@68525|delta/epsilon subdivisions,2YRAD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Chemoreceptor zinc-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CZB,GGDEF
k59_1497924_2	709032.Sulku_2320	1.21e-55	174.0	2A14F@1|root,30PAA@2|Bacteria,1Q6CF@1224|Proteobacteria,432V8@68525|delta/epsilon subdivisions,2YSWU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_207835_1	352165.HMPREF7215_2591	6.19e-29	115.0	COG5410@1|root,COG5410@2|Bacteria	2|Bacteria	K	chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6,Terminase_6C
k59_207839_1	1537917.JU82_04695	2.3e-120	350.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,42MKH@68525|delta/epsilon subdivisions,2YMWK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	malonyl coa-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
k59_1151426_1	159087.Daro_0179	1.46e-112	334.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,2VH51@28216|Betaproteobacteria,2KVTM@206389|Rhodocyclales	206389|Rhodocyclales	O	Collagenase and related proteases	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
k59_567083_1	709032.Sulku_0269	3.35e-38	140.0	COG0493@1|root,COG1894@1|root,COG0493@2|Bacteria,COG1894@2|Bacteria,1MU2H@1224|Proteobacteria,42M6X@68525|delta/epsilon subdivisions,2YM9W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COGs COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase	-	-	1.17.1.10	ko:K15022	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00377	R00134	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_20,NADH_4Fe-4S,Pyr_redox_2
k59_567083_2	1172190.M947_04155	1.83e-30	108.0	2AITQ@1|root,319AS@2|Bacteria,1Q26T@1224|Proteobacteria,42V2V@68525|delta/epsilon subdivisions,2YQFN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	putative NADH-ubiquinone oxidoreductase chain E	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADH-UOR_E
k59_621563_1	1537917.JU82_11855	3.12e-200	578.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,42MRQ@68525|delta/epsilon subdivisions,2YMJY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1g
k59_1733264_1	1488328.JMCL01000009_gene4867	9.74e-59	186.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,1S3PX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	iJN746.PP_0560	DHquinase_II
k59_1733264_2	1348657.M622_10925	7.11e-07	50.4	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,2VI8I@28216|Betaproteobacteria,2KV4F@206389|Rhodocyclales	206389|Rhodocyclales	CO	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
k59_1318791_1	709032.Sulku_0151	2.95e-162	462.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42MTX@68525|delta/epsilon subdivisions,2YMNH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	pseC	-	2.6.1.92	ko:K15895	ko00520,map00520	-	R09825	RC00006,RC00781	ko00000,ko00001,ko01000	-	-	-	DegT_DnrJ_EryC1
k59_318837_2	395494.Galf_1850	2.18e-49	160.0	COG5652@1|root,COG5652@2|Bacteria,1NGE7@1224|Proteobacteria,2W5S7@28216|Betaproteobacteria,44WK1@713636|Nitrosomonadales	28216|Betaproteobacteria	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
k59_1204542_1	1249480.B649_00020	1.78e-130	384.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1RGCV@1224|Proteobacteria,42M47@68525|delta/epsilon subdivisions,2YMRS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	(EAL) domain protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_1271064_1	1249480.B649_11640	3.57e-96	295.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,42MEM@68525|delta/epsilon subdivisions,2YMWQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
k59_1151477_1	768671.ThimaDRAFT_3828	4.31e-68	231.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,COG1146@2|Bacteria,1MVM0@1224|Proteobacteria,1RNNX@1236|Gammaproteobacteria,1WX9H@135613|Chromatiales	135613|Chromatiales	C	pyruvate flavodoxin ferredoxin oxidoreductase	-	-	1.2.7.1	ko:K00169,ko:K03737	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034,R10866	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_13,Fer4_6,PFOR_II,POR,POR_N,TPP_enzyme_C
k59_1204559_1	709032.Sulku_0416	2.92e-29	112.0	COG1357@1|root,COG1357@2|Bacteria,1N7U9@1224|Proteobacteria,42X3G@68525|delta/epsilon subdivisions,2YQWW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Pentapeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
k59_1204559_2	1279015.KB908456_gene1495	6.61e-05	45.8	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1Y3ZA@135624|Aeromonadales	135624|Aeromonadales	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF,PAS_9
k59_1381515_1	1537917.JU82_01115	4.74e-94	280.0	COG0788@1|root,COG0788@2|Bacteria,1MVCF@1224|Proteobacteria,42MPM@68525|delta/epsilon subdivisions,2YMX5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT,Formyl_trans_N
k59_28023_1	387093.SUN_0687	5.15e-79	263.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42NCZ@68525|delta/epsilon subdivisions,2YNKW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	czcA	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
k59_1204587_1	709032.Sulku_2026	3.77e-61	208.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,42KZI@68525|delta/epsilon subdivisions,2YR60@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Domain of unknown function (DUF3458_C) ARM repeats	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,Peptidase_M1
k59_584419_1	1165841.SULAR_05408	9.59e-39	132.0	COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,42SH8@68525|delta/epsilon subdivisions,2YPDX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	GatB Yqey family protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
k59_584419_3	1165841.SULAR_05393	3.61e-41	145.0	COG0457@1|root,COG0457@2|Bacteria,1NRB9@1224|Proteobacteria,42W0K@68525|delta/epsilon subdivisions,2YQ9W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_2,TPR_8
k59_397076_1	1304888.ATWF01000001_gene985	3.02e-76	240.0	COG0859@1|root,COG0859@2|Bacteria,2GG3S@200930|Deferribacteres	200930|Deferribacteres	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
k59_282643_1	55529.EKX46932	9.81e-40	145.0	KOG1406@1|root,KOG1406@2759|Eukaryota	2759|Eukaryota	I	propanoyl-CoA C-acyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
k59_335759_1	1249480.B649_04095	1.63e-112	330.0	COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1RD7I@1224|Proteobacteria,42SM8@68525|delta/epsilon subdivisions,2YPEY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Response regulator receiver	-	-	-	ko:K03415	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CheW,Response_reg
k59_1056541_1	1165841.SULAR_06038	4.37e-58	197.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,42MVQ@68525|delta/epsilon subdivisions,2YMEZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CO	Thiol disulfide interchange protein	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin,Thioredoxin_2,Thioredoxin_7
k59_702596_1	1521187.JPIM01000030_gene1506	2.31e-23	99.8	COG1304@1|root,COG1304@2|Bacteria,2G5RF@200795|Chloroflexi,374UE@32061|Chloroflexia	32061|Chloroflexia	H	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)	fni	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_dh
k59_702596_2	467661.RKLH11_3931	2.9e-119	354.0	COG1257@1|root,COG1257@2|Bacteria,1Q6M1@1224|Proteobacteria,2U1F3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	COG1257 Hydroxymethylglutaryl-CoA reductase	-	-	1.1.1.34	ko:K00021	ko00900,ko01100,ko01110,ko01130,ko04152,ko04976,map00900,map01100,map01110,map01130,map04152,map04976	M00095	R02082	RC00004,RC00644	ko00000,ko00001,ko00002,ko01000	-	-	-	HMG-CoA_red
k59_1288205_1	709032.Sulku_0034	1.18e-73	239.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,43BRF@68525|delta/epsilon subdivisions,2YNRK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	TonB-dependent receptor plug	-	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
k59_1583060_1	1249480.B649_01870	6.69e-12	64.7	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42NHE@68525|delta/epsilon subdivisions,2YMQ8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
k59_814780_1	477228.YO5_02468	1.13e-21	91.3	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,1RM8I@1236|Gammaproteobacteria,1Z1F1@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iJN746.PP_4715	TIM
k59_520966_1	159087.Daro_3314	8.4e-14	69.7	COG0277@1|root,COG0277@2|Bacteria,1MVYV@1224|Proteobacteria,2VHUQ@28216|Betaproteobacteria,2KUSX@206389|Rhodocyclales	206389|Rhodocyclales	C	FAD binding	glcE	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD-oxidase_C,FAD_binding_4
k59_520966_2	159087.Daro_3313	4.52e-168	480.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,2VISA@28216|Betaproteobacteria,2KUHR@206389|Rhodocyclales	206389|Rhodocyclales	C	glycolate oxidase iron-sulfur subunit	glcF	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_7
k59_1874510_1	1249480.B649_04410	5.91e-12	70.5	COG1187@1|root,COG1187@2|Bacteria,1QZ1N@1224|Proteobacteria,430HW@68525|delta/epsilon subdivisions,2YS1F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	pseudouridine synthase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1398459_2	709032.Sulku_1544	2.19e-70	214.0	COG1393@1|root,COG1393@2|Bacteria,1MZ7Z@1224|Proteobacteria,42VII@68525|delta/epsilon subdivisions,2YSA0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	ArsC
k59_1398459_3	709032.Sulku_1136	3.53e-16	74.7	COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,42UAA@68525|delta/epsilon subdivisions,2YS1D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	peptidyl-prolyl	-	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
k59_1634494_1	159087.Daro_0850	1.61e-46	154.0	2E3EJ@1|root,32YDJ@2|Bacteria,1N8MS@1224|Proteobacteria,2VW4J@28216|Betaproteobacteria,2KXBM@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1634494_2	159087.Daro_0849	6.15e-07	48.5	29J60@1|root,3063D@2|Bacteria,1QRJ5@1224|Proteobacteria,2W9X9@28216|Betaproteobacteria,2KXK8@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_225043_1	1132855.KB913035_gene222	3.64e-21	89.4	COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,2VR3B@28216|Betaproteobacteria,2KMP1@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
k59_225043_2	1502770.JQMG01000001_gene830	7.35e-87	273.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,2VIGG@28216|Betaproteobacteria,2KMCJ@206350|Nitrosomonadales	206350|Nitrosomonadales	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
k59_1752322_1	1239962.C943_02905	5.9e-20	95.1	COG2203@1|root,COG4251@1|root,COG2203@2|Bacteria,COG4251@2|Bacteria,4PM99@976|Bacteroidetes,47Y55@768503|Cytophagia	976|Bacteroidetes	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_9,Response_reg,Y_Y_Y
k59_1752322_2	387093.SUN_1067	9.13e-32	117.0	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,43ADP@68525|delta/epsilon subdivisions,2YT26@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_1634503_1	709032.Sulku_1039	2.88e-89	279.0	COG0745@1|root,COG2208@1|root,COG0745@2|Bacteria,COG2208@2|Bacteria,1P8H1@1224|Proteobacteria,43CBP@68525|delta/epsilon subdivisions,2YNYZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,Response_reg,SpoIIE
k59_931556_1	709032.Sulku_2491	1.83e-278	785.0	COG0243@1|root,COG0243@2|Bacteria,1NSXR@1224|Proteobacteria,43BQI@68525|delta/epsilon subdivisions,2YRHF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	ko:K17050	-	-	-	-	ko00000,ko02000	5.A.3.8	-	-	Molybdopterin,Molydop_binding
k59_521006_1	497321.C664_08703	3.11e-143	427.0	COG1061@1|root,COG1061@2|Bacteria,1PY93@1224|Proteobacteria,2VM91@28216|Betaproteobacteria	28216|Betaproteobacteria	KL	T5orf172	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1398493_1	159087.Daro_0835	7.48e-44	144.0	2EB0P@1|root,330T4@2|Bacteria,1QAEY@1224|Proteobacteria,2VWEP@28216|Betaproteobacteria,2M035@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_458098_1	159087.Daro_1441	2.51e-62	213.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG2972@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG2972@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
k59_1691409_1	159087.Daro_3796	4.65e-118	345.0	2DB9W@1|root,2Z7Z9@2|Bacteria,1MZFV@1224|Proteobacteria,2VHWP@28216|Betaproteobacteria,2KVEW@206389|Rhodocyclales	206389|Rhodocyclales	C	Methane/Phenol/Toluene Hydroxylase	-	-	-	ko:K16243	ko00361,ko00362,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00623,map01100,map01120,map01220	M00548	R03560,R03608,R10042,R10043	RC00046,RC00490	ko00000,ko00001,ko00002	-	-	-	Phenol_Hydrox
k59_1056644_1	748247.AZKH_0029	1.27e-104	312.0	COG1960@1|root,COG1960@2|Bacteria,1MUK0@1224|Proteobacteria,2VHDV@28216|Betaproteobacteria,2KVXG@206389|Rhodocyclales	206389|Rhodocyclales	C	CATALYZES THE OXIDATIVE DECARBOXYLATION OF GLUTARYL-COA TO CROTONYL-COA AND CO(2) IN THE DEGRADATIVE PATHWAY OF L-LYSINE L-HYDROXYLYSINE AND L-TRYPTOPHAN METABOLISM. IT USES ELECTRON TRANSFER FLAVOPROTEIN AS ITS ELECTRON ACCEPTOR. Entry name	gcdH	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_1288292_1	1165841.SULAR_07875	1.6e-104	313.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,42NKY@68525|delta/epsilon subdivisions,2YN43@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
k59_458110_1	946483.Cenrod_1536	1.5e-19	95.1	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG2202@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria,4AA9F@80864|Comamonadaceae	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_9,Response_reg
k59_335882_1	709032.Sulku_1195	1.26e-43	146.0	COG0847@1|root,COG0847@2|Bacteria,1QA0P@1224|Proteobacteria,42RPG@68525|delta/epsilon subdivisions,2YPAU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Exonuclease	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_44690_1	1123393.KB891330_gene758	4.25e-90	272.0	COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,2VHGS@28216|Betaproteobacteria,1KSC5@119069|Hydrogenophilales	119069|Hydrogenophilales	C	N-terminal domain of cytochrome oxidase-cbb3, FixP	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,FixP_N
k59_1221944_1	1249480.B649_11565	2.25e-39	138.0	COG3439@1|root,COG3439@2|Bacteria,1RBWN@1224|Proteobacteria,43BBQ@68525|delta/epsilon subdivisions,2YT7G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1583228_1	709032.Sulku_1150	1.88e-109	337.0	COG4774@1|root,COG4774@2|Bacteria,1QU2Y@1224|Proteobacteria,43CFU@68525|delta/epsilon subdivisions,2YTF6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	PFAM TonB-dependent Receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	TonB_dep_Rec
k59_1807815_1	1408444.JHYC01000007_gene2247	1.2e-12	66.2	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1RNU8@1236|Gammaproteobacteria,1JDWS@118969|Legionellales	118969|Legionellales	J	Belongs to the SUA5 family	-	-	-	-	-	-	-	-	-	-	-	-	Sua5_yciO_yrdC
k59_1807815_2	2340.JV46_18810	1.33e-45	158.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,1RNDC@1236|Gammaproteobacteria,1J4WF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
k59_169361_1	1384056.N787_06335	1.05e-25	108.0	COG4977@1|root,COG4977@2|Bacteria,1MUDK@1224|Proteobacteria,1RP9W@1236|Gammaproteobacteria,1X81C@135614|Xanthomonadales	135614|Xanthomonadales	K	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
k59_584645_2	1161935.H9D1H2_9CAUD	2.86e-22	94.7	4QFIC@10239|Viruses,4QXG2@35237|dsDNA viruses  no RNA stage,4QTVA@28883|Caudovirales,4QNVH@10744|Podoviridae	10744|Podoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_931683_1	580332.Slit_0838	8.19e-37	131.0	COG1433@1|root,COG1433@2|Bacteria,1PW6J@1224|Proteobacteria,2VNDT@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Dinitrogenase iron-molybdenum cofactor, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	DIMCO_N,Nitro_FeMo-Co
k59_1170192_1	1249480.B649_01820	1.18e-79	256.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YMHP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3
k59_1807847_1	709032.Sulku_0557	4.2e-135	386.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,42N0I@68525|delta/epsilon subdivisions,2YMW1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
k59_584686_2	1249480.B649_07615	4.11e-30	120.0	COG1315@1|root,COG1315@2|Bacteria,1R5P6@1224|Proteobacteria,42MAS@68525|delta/epsilon subdivisions,2YM7Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Flagellar Assembly Protein A	-	-	-	-	-	-	-	-	-	-	-	-	FapA
k59_931725_2	1123368.AUIS01000013_gene872	1.33e-46	152.0	COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,1S973@1236|Gammaproteobacteria,2ND3N@225057|Acidithiobacillales	225057|Acidithiobacillales	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
k59_584690_1	439235.Dalk_1317	3.9e-69	223.0	COG3039@1|root,COG3039@2|Bacteria,1MVTU@1224|Proteobacteria,42Q03@68525|delta/epsilon subdivisions,2WMFQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Transposase domain (DUF772)	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_1583283_1	46234.ANA_C13043	1.51e-27	103.0	COG1487@1|root,COG1487@2|Bacteria,1GHGW@1117|Cyanobacteria,1HSVH@1161|Nostocales	1117|Cyanobacteria	S	ribonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	PIN
k59_1170260_1	1454004.AW11_02103	1.15e-14	73.9	COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,2VI47@28216|Betaproteobacteria,1KQMU@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	G	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_2
k59_1170260_2	1304883.KI912532_gene352	4.34e-55	176.0	2ANPA@1|root,31DNS@2|Bacteria,1RHTE@1224|Proteobacteria,2VRS4@28216|Betaproteobacteria,2KWF5@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF3833)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3833
k59_868089_1	1249480.B649_00210	9.92e-109	342.0	COG4581@1|root,COG4581@2|Bacteria,1MVD6@1224|Proteobacteria,42PR3@68525|delta/epsilon subdivisions,2YN2Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Mitochondrial degradasome RNA helicase subunit C terminal	-	-	3.6.4.13	ko:K17675	-	-	-	-	ko00000,ko01000,ko03029	-	-	-	Helicase_C,SUV3_C
k59_1515742_1	1268622.AVS7_03975	1.78e-68	209.0	COG2236@1|root,COG2236@2|Bacteria,1R675@1224|Proteobacteria,2VPZG@28216|Betaproteobacteria,4AA1G@80864|Comamonadaceae	28216|Betaproteobacteria	F	PFAM Phosphoribosyltransferase	gpt	-	-	ko:K07101	-	-	-	-	ko00000	-	-	-	Pribosyltran
k59_101267_1	387093.SUN_0572	1.67e-96	289.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,42KZJ@68525|delta/epsilon subdivisions,2YMR0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
k59_1222024_1	1255043.TVNIR_1958	7.42e-53	185.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RN8P@1236|Gammaproteobacteria,1WWIV@135613|Chromatiales	135613|Chromatiales	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
k59_1170292_1	709032.Sulku_2649	7.48e-230	641.0	COG1538@1|root,COG1538@2|Bacteria,1QWWG@1224|Proteobacteria,42PH5@68525|delta/epsilon subdivisions,2YMHH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_1874754_1	1249480.B649_02120	3.61e-47	167.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2YMW4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_1874754_2	709032.Sulku_0433	2.24e-29	117.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,42NIH@68525|delta/epsilon subdivisions,2YMVT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	FP	Guanosine pentaphosphate phosphohydrolase	gppA	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
k59_397421_1	1537917.JU82_00610	1.11e-07	50.4	2BRG4@1|root,32MA7@2|Bacteria,1Q36H@1224|Proteobacteria,42WUT@68525|delta/epsilon subdivisions,2YQQJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_397421_2	1537917.JU82_00605	1.6e-107	320.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,42MS9@68525|delta/epsilon subdivisions,2YMBY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
k59_1634742_1	395494.Galf_1584	1.09e-25	104.0	COG3259@1|root,COG3259@2|Bacteria,1QUQ7@1224|Proteobacteria,2VJT0@28216|Betaproteobacteria,44WEG@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	hoxH	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.12.1.2	ko:K00436	-	-	R00700	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
k59_1634742_2	395494.Galf_1585	7.93e-27	102.0	COG0680@1|root,COG0680@2|Bacteria,1MZE1@1224|Proteobacteria,2VTPX@28216|Betaproteobacteria,44WKQ@713636|Nitrosomonadales	28216|Betaproteobacteria	C	hydrogenase maturation protease	hoxW	-	-	-	-	-	-	-	-	-	-	-	-
k59_815044_1	1123518.ARWI01000001_gene1501	1.09e-52	166.0	COG0636@1|root,COG0636@2|Bacteria,1R359@1224|Proteobacteria,1T63K@1236|Gammaproteobacteria,461DV@72273|Thiotrichales	72273|Thiotrichales	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
k59_815044_2	1168067.JAGP01000001_gene2091	1.09e-35	128.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,1RPHK@1236|Gammaproteobacteria,460DM@72273|Thiotrichales	72273|Thiotrichales	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
k59_1464481_1	990073.ATHU01000005_gene1867	1.03e-117	353.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,42M81@68525|delta/epsilon subdivisions,2YMTF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_816781_1	765911.Thivi_1372	3.42e-89	272.0	COG2829@1|root,COG2829@2|Bacteria,1PC8I@1224|Proteobacteria,1RMJH@1236|Gammaproteobacteria,1WY7I@135613|Chromatiales	135613|Chromatiales	M	PFAM phospholipase A1	-	-	3.1.1.32,3.1.1.4	ko:K01058	ko00564,ko00565,ko00590,ko00591,ko00592,ko01100,ko01110,map00564,map00565,map00590,map00591,map00592,map01100,map01110	-	R01315,R01316,R01317,R02053,R02054,R04034,R07064,R07379,R07387,R07859,R07860	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko01000	-	-	-	PLA1
k59_1340157_1	358220.C380_08435	1.96e-118	344.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,2VI9W@28216|Betaproteobacteria,4AARC@80864|Comamonadaceae	28216|Betaproteobacteria	O	HflC and HflK could regulate a protease	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
k59_1517617_1	1165841.SULAR_04502	3.19e-92	284.0	COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,42NZ4@68525|delta/epsilon subdivisions,2YNNY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	COG2067 Long-chain fatty acid transport protein	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k59_1517617_2	387093.SUN_0589	3.06e-08	54.7	COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,42P0U@68525|delta/epsilon subdivisions,2YNIG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	AI-2E family transporter	-	-	-	ko:K11744	-	-	-	-	ko00000	-	-	-	AI-2E_transport
k59_1340169_1	29581.BW37_05092	5.37e-105	342.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,2VI2R@28216|Betaproteobacteria,4730W@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	extracellular alpha-helical protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1
k59_1809491_1	865861.AZSU01000008_gene667	5.16e-10	67.0	COG2199@1|root,COG3706@2|Bacteria,1V9Y7@1239|Firmicutes,24A8B@186801|Clostridia,36E8P@31979|Clostridiaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GGDEF,Pkinase,TPR_12,TPR_8
k59_1636548_1	709032.Sulku_0002	2.81e-40	142.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,42NQW@68525|delta/epsilon subdivisions,2YM9J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
k59_1693099_1	1249480.B649_11795	8.04e-57	186.0	COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,42MDF@68525|delta/epsilon subdivisions,2YMNI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Pseudouridine synthase	sfhB	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
k59_1693099_2	709032.Sulku_2546	4.81e-27	108.0	COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,42P71@68525|delta/epsilon subdivisions,2YNAA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Phospholipid glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5,Acyltransferase
k59_869596_1	387093.SUN_1569	4.37e-54	182.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,42M6T@68525|delta/epsilon subdivisions,2YMJD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
k59_869596_2	387093.SUN_1567	5.9e-60	192.0	2ENG1@1|root,33G3G@2|Bacteria,1NPIZ@1224|Proteobacteria,42ZV2@68525|delta/epsilon subdivisions,2YRT3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1172249_1	709032.Sulku_0269	2.88e-133	395.0	COG0493@1|root,COG1894@1|root,COG0493@2|Bacteria,COG1894@2|Bacteria,1MU2H@1224|Proteobacteria,42M6X@68525|delta/epsilon subdivisions,2YM9W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COGs COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase	-	-	1.17.1.10	ko:K15022	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00377	R00134	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_20,NADH_4Fe-4S,Pyr_redox_2
k59_226346_1	1249480.B649_01545	4.51e-100	295.0	COG0847@1|root,COG0847@2|Bacteria,1PDD1@1224|Proteobacteria,42MUX@68525|delta/epsilon subdivisions,2YNB6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG0847 DNA polymerase III epsilon subunit and related 3'-5'	-	-	2.7.7.7	ko:K02342,ko:K10857	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_1223505_1	709032.Sulku_2474	3.38e-49	173.0	29Y2F@1|root,30JVD@2|Bacteria,1RAWX@1224|Proteobacteria,4300B@68525|delta/epsilon subdivisions,2YRWY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_284901_1	583345.Mmol_1967	9.31e-67	211.0	COG3219@1|root,COG3219@2|Bacteria,1R8C9@1224|Proteobacteria,2VPVN@28216|Betaproteobacteria,2KMRC@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Putative DNA-binding domain	-	-	-	ko:K09929	-	-	-	-	ko00000	-	-	-	DUF2063
k59_399411_1	1172190.M947_00425	5.83e-38	134.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,42MD3@68525|delta/epsilon subdivisions,2YMMW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Oxidoreductase	oorB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
k59_399411_2	326298.Suden_1053	5.58e-208	582.0	COG0674@1|root,COG0674@2|Bacteria,1NBSJ@1224|Proteobacteria,42MS1@68525|delta/epsilon subdivisions,2YMD2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Oxidoreductase	oorA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
k59_996255_1	709032.Sulku_0686	7.21e-18	82.4	COG3391@1|root,COG3391@2|Bacteria,1QUIK@1224|Proteobacteria,42RTQ@68525|delta/epsilon subdivisions,2YPA4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	amine dehydrogenase activity	napL	-	-	-	-	-	-	-	-	-	-	-	-
k59_996255_2	709032.Sulku_0687	1.84e-75	228.0	COG1149@1|root,COG1149@2|Bacteria,1QZ2E@1224|Proteobacteria,42TQN@68525|delta/epsilon subdivisions,2YPUZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	ferredoxin-type protein NapF	napF	-	-	ko:K02572	-	-	-	-	ko00000	-	-	-	Fer4
k59_1517701_1	220341.16504807	1.35e-11	70.1	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,1RPPQ@1236|Gammaproteobacteria,3ZJPF@590|Salmonella	1236|Gammaproteobacteria	C	Di-haem cytochrome c peroxidase	yhjA	GO:0000302,GO:0003674,GO:0003824,GO:0004130,GO:0004601,GO:0005488,GO:0006091,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009061,GO:0009636,GO:0009987,GO:0010035,GO:0015980,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017144,GO:0019645,GO:0020037,GO:0022900,GO:0022904,GO:0042221,GO:0042493,GO:0042542,GO:0042743,GO:0044237,GO:0045333,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051716,GO:0055114,GO:0070887,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1990748	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C,Haem_bd
k59_1775370_1	666681.M301_0981	9.46e-20	84.3	2ATZM@1|root,31JJE@2|Bacteria,1RIFX@1224|Proteobacteria,2VSS3@28216|Betaproteobacteria,2KNX8@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1775370_2	1304883.KI912532_gene1323	1.32e-87	261.0	COG2518@1|root,COG2518@2|Bacteria,1QWH0@1224|Proteobacteria,2WGZH@28216|Betaproteobacteria,2KYXU@206389|Rhodocyclales	206389|Rhodocyclales	O	Thiopurine S-methyltransferase (TPMT)	-	-	-	-	-	-	-	-	-	-	-	-	TPMT
k59_1425338_1	709032.Sulku_1413	9.47e-25	94.4	COG1669@1|root,COG1669@2|Bacteria,1Q2XW@1224|Proteobacteria,42WFS@68525|delta/epsilon subdivisions,2YQEU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
k59_1425338_2	709032.Sulku_1414	1.69e-67	206.0	COG2361@1|root,COG2361@2|Bacteria,1Q26B@1224|Proteobacteria,42V23@68525|delta/epsilon subdivisions,2YQ6I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
k59_1188132_1	159087.Daro_2767	3.97e-84	252.0	COG3945@1|root,COG3945@2|Bacteria,1N12K@1224|Proteobacteria,2VUPY@28216|Betaproteobacteria,2KWW8@206389|Rhodocyclales	206389|Rhodocyclales	S	Hemerythrin HHE cation binding	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
k59_249492_1	159087.Daro_3731	1.87e-78	237.0	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,2VQNU@28216|Betaproteobacteria,2KV6M@206389|Rhodocyclales	206389|Rhodocyclales	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
k59_249492_2	1323361.JPOC01000057_gene3199	5.13e-08	53.9	COG0193@1|root,COG0193@2|Bacteria,2GKCV@201174|Actinobacteria,4FWYC@85025|Nocardiaceae	201174|Actinobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
k59_70895_1	317025.Tcr_1817	1.62e-38	143.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,1RMPS@1236|Gammaproteobacteria,4608P@72273|Thiotrichales	72273|Thiotrichales	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
k59_1836906_1	395494.Galf_0449	1.63e-107	332.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,2VKSY@28216|Betaproteobacteria,44V4I@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
k59_1775391_1	596154.Alide2_3873	1.9e-103	309.0	COG4447@1|root,COG4447@2|Bacteria,1R84R@1224|Proteobacteria,2VMQ1@28216|Betaproteobacteria,4AEMT@80864|Comamonadaceae	28216|Betaproteobacteria	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
k59_1482790_1	709032.Sulku_0556	1.13e-09	58.2	COG0642@1|root,COG0642@2|Bacteria,1N5IQ@1224|Proteobacteria,42M9P@68525|delta/epsilon subdivisions,2YN0U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	cprS	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
k59_1482790_2	1537917.JU82_03260	1.26e-113	330.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,42N0I@68525|delta/epsilon subdivisions,2YMW1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
k59_602281_1	1304883.KI912532_gene2741	6.86e-41	152.0	COG0642@1|root,COG0715@1|root,COG2203@1|root,COG0715@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,Response_reg
k59_1250111_1	1537917.JU82_08270	4.37e-171	489.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,42MEU@68525|delta/epsilon subdivisions,2YMUF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
k59_895093_1	90813.JQMT01000001_gene1298	8.7e-77	240.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,1RN3A@1236|Gammaproteobacteria,45ZSI@72273|Thiotrichales	72273|Thiotrichales	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
k59_133717_1	1537917.JU82_01885	2.36e-86	261.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,42NBV@68525|delta/epsilon subdivisions,2YM8U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
k59_133717_2	563040.Saut_1922	3.3e-11	61.6	COG0602@1|root,COG0602@2|Bacteria,1PDNI@1224|Proteobacteria,42R24@68525|delta/epsilon subdivisions,2YN2N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_12,Fer4_14
k59_189285_1	1249480.B649_04180	4.92e-42	153.0	COG1418@1|root,COG1418@2|Bacteria,1P7YA@1224|Proteobacteria,42KZ8@68525|delta/epsilon subdivisions,2YMQS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
k59_1775449_1	1537917.JU82_07890	1.29e-82	257.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42Z0P@68525|delta/epsilon subdivisions,2YR4F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG0513 Superfamily II DNA and RNA	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k59_1015431_1	342610.Patl_3240	6.8e-24	99.4	COG1682@1|root,COG1682@2|Bacteria,1MUTE@1224|Proteobacteria,1RZ4T@1236|Gammaproteobacteria,2Q2IY@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	P	ABC-2 type transporter	kpsM	-	-	ko:K09688	ko02010,map02010	M00249	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.101	-	-	ABC2_membrane
k59_1132044_1	159087.Daro_2978	2.79e-89	274.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,2VIG2@28216|Betaproteobacteria,2KUKU@206389|Rhodocyclales	206389|Rhodocyclales	O	HflC and HflK could encode or regulate a protease	-	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7,HflK_N
k59_365359_1	1165841.SULAR_02428	1.75e-16	76.6	COG4902@1|root,COG4902@2|Bacteria	2|Bacteria	-	-	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	DUF2202
k59_837644_1	187272.Mlg_0558	4.43e-26	112.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,1RNM1@1236|Gammaproteobacteria,1WW8I@135613|Chromatiales	135613|Chromatiales	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
k59_133766_1	709032.Sulku_2220	2.88e-195	558.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,42MFA@68525|delta/epsilon subdivisions,2YMUE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
k59_602323_2	709032.Sulku_2377	1.69e-47	166.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,42MEI@68525|delta/epsilon subdivisions,2YN3Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Asparagine synthase, glutamine-hydrolyzing	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_955280_1	709032.Sulku_1270	7.51e-186	532.0	COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,42NYT@68525|delta/epsilon subdivisions,2YNMV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
k59_715562_1	1458357.BG58_07860	9.54e-79	253.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,2VKU8@28216|Betaproteobacteria,1K2SP@119060|Burkholderiaceae	28216|Betaproteobacteria	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
k59_1015457_1	572480.Arnit_0993	6.78e-09	59.3	COG0582@1|root,COG0582@2|Bacteria,1MVZB@1224|Proteobacteria,42M9T@68525|delta/epsilon subdivisions,2YNIB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K14059	-	-	-	-	ko00000	-	-	-	Phage_int_SAM_3,Phage_integrase
k59_1425463_1	709032.Sulku_2452	8.94e-45	160.0	COG2199@1|root,COG5000@1|root,COG2199@2|Bacteria,COG5000@2|Bacteria,1RGCV@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_4,PAS_9,Response_reg
k59_133785_1	387093.SUN_1850	7.27e-73	235.0	COG2374@1|root,COG2374@2|Bacteria,1RCTI@1224|Proteobacteria,42Q2J@68525|delta/epsilon subdivisions,2YNG1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
k59_14840_1	1121035.AUCH01000012_gene2997	6.93e-79	242.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2VJI3@28216|Betaproteobacteria,2KVD7@206389|Rhodocyclales	206389|Rhodocyclales	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_1658297_1	709032.Sulku_0100	2.79e-65	202.0	COG0421@1|root,COG0421@2|Bacteria,1PD55@1224|Proteobacteria,42UAB@68525|delta/epsilon subdivisions,2YPTY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synt_N,Spermine_synth
k59_1658297_2	1249480.B649_00435	2.16e-43	146.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,42RI5@68525|delta/epsilon subdivisions,2YP6Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0831	CoaE
k59_1132091_2	1249480.B649_05335	4.09e-53	183.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42MS0@68525|delta/epsilon subdivisions,2YMTX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_1837034_1	1249480.B649_11460	7.98e-154	452.0	COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MWDY@1224|Proteobacteria,43BJD@68525|delta/epsilon subdivisions,2YNEB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	2-acylglycerophosphoethanolamine acyltransferase	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase
k59_1482863_1	1165841.SULAR_03782	7.3e-49	176.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42MX5@68525|delta/epsilon subdivisions,2YMSQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)	-	-	2.7.7.13,5.4.2.8	ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II
k59_955317_2	709032.Sulku_1164	2.15e-195	551.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,42M90@68525|delta/epsilon subdivisions,2YMR5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k59_1132105_1	1249480.B649_10575	2.34e-45	152.0	2AJ1F@1|root,319JK@2|Bacteria,1Q2YN@1224|Proteobacteria,42WGN@68525|delta/epsilon subdivisions,2YQK8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1132105_2	1249480.B649_10580	7.1e-20	83.2	COG2165@1|root,COG2165@2|Bacteria,1PTBM@1224|Proteobacteria,42XHE@68525|delta/epsilon subdivisions,2YQVZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
k59_1250206_1	159087.Daro_0047	6.52e-68	210.0	COG2913@1|root,COG2913@2|Bacteria,1RBY9@1224|Proteobacteria,2VSW7@28216|Betaproteobacteria,2KWQU@206389|Rhodocyclales	206389|Rhodocyclales	J	(Lipo)protein	-	-	-	-	-	-	-	-	-	-	-	-	SmpA_OmlA
k59_837695_1	709032.Sulku_0565	1.27e-174	491.0	COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1N81M@1224|Proteobacteria,42M00@68525|delta/epsilon subdivisions,2YMF1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	chemotaxis protein	cheV	-	-	ko:K03415	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CheW,Response_reg
k59_70995_1	387093.SUN_0169	1e-69	228.0	COG2956@1|root,COG2956@2|Bacteria,1PDTB@1224|Proteobacteria,42PNY@68525|delta/epsilon subdivisions,2YN3M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	ciaB	-	-	-	-	-	-	-	-	-	-	-	-
k59_1482872_2	709032.Sulku_1314	1.19e-62	202.0	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,42MSF@68525|delta/epsilon subdivisions,2YNA7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	alanine dehydrogenase	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
k59_837704_1	1076550.LH22_06290	4.18e-37	137.0	COG0438@1|root,COG0438@2|Bacteria,1R662@1224|Proteobacteria,1RREQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
k59_1132128_1	1132855.KB913035_gene364	1.18e-127	370.0	COG1686@1|root,COG1686@2|Bacteria,1MWZA@1224|Proteobacteria,2VH1S@28216|Betaproteobacteria,2KMAQ@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Belongs to the peptidase S11 family	-	-	-	ko:K07262	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
k59_1015532_1	159087.Daro_1505	2.83e-127	373.0	COG2710@1|root,COG2710@2|Bacteria,1MWSX@1224|Proteobacteria,2VJNA@28216|Betaproteobacteria,2KV3F@206389|Rhodocyclales	206389|Rhodocyclales	C	Nitrogenase component 1 type Oxidoreductase	-	-	-	ko:K02592	-	-	-	-	ko00000	-	-	-	Oxidored_nitro
k59_1658359_1	379066.GAU_0508	1.24e-67	216.0	COG3336@1|root,COG3336@2|Bacteria,1ZT56@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)	-	-	-	-	-	-	-	-	-	-	-	-	Caa3_CtaG
k59_955371_1	1537917.JU82_03810	1.11e-22	97.1	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,42MB1@68525|delta/epsilon subdivisions,2YMVC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
k59_955371_2	1537917.JU82_03805	1.86e-87	258.0	COG3829@1|root,COG3829@2|Bacteria,1RH32@1224|Proteobacteria,42T1B@68525|delta/epsilon subdivisions,2YPHF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	ko:K03776	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	PAS_3
k59_955371_3	1537917.JU82_03800	7.87e-13	67.4	COG2198@1|root,COG2198@2|Bacteria,1PCKH@1224|Proteobacteria,42W9Z@68525|delta/epsilon subdivisions,2YQ6K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1775548_1	929558.SMGD1_1356	1.22e-103	301.0	COG2077@1|root,COG2077@2|Bacteria,1RAJ9@1224|Proteobacteria,42RE8@68525|delta/epsilon subdivisions,2YP3Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	tpx	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	Redoxin
k59_837755_1	1165841.SULAR_07108	7.62e-109	324.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,42MMF@68525|delta/epsilon subdivisions,2YMPB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Glycerol-3-phosphate dehydrogenase	glpC	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_17,Fer4_7,Fer4_8
k59_306521_1	709032.Sulku_0582	1.95e-64	202.0	29VYJ@1|root,30HGQ@2|Bacteria,1Q33E@1224|Proteobacteria,42WQE@68525|delta/epsilon subdivisions,2YQMM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1546329_1	90814.KL370891_gene227	3.2e-84	278.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,1RMK0@1236|Gammaproteobacteria,46008@72273|Thiotrichales	72273|Thiotrichales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_605010_1	1249480.B649_03515	3.2e-13	68.6	COG1792@1|root,COG1792@2|Bacteria,1QB26@1224|Proteobacteria,42MF4@68525|delta/epsilon subdivisions,2YNT9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Rod shape-determining protein MreC	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
k59_605010_2	1249480.B649_03520	1.04e-227	629.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,42M1J@68525|delta/epsilon subdivisions,2YMHT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	rod shape-determining protein mreB	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
k59_367584_2	159087.Daro_0115	3.14e-158	449.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,2VK0Y@28216|Betaproteobacteria,2KUC9@206389|Rhodocyclales	206389|Rhodocyclales	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
k59_1134995_1	929558.SMGD1_0316	3.75e-22	92.4	COG0745@1|root,COG0745@2|Bacteria,1NW7Q@1224|Proteobacteria,42S6J@68525|delta/epsilon subdivisions,2YPCA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_1134995_2	1454202.PPBDW_131275___1	3.62e-14	75.5	COG2199@1|root,COG2204@1|root,COG2204@2|Bacteria,COG3706@2|Bacteria,1MXBG@1224|Proteobacteria,1RNJA@1236|Gammaproteobacteria,1XSJA@135623|Vibrionales	135623|Vibrionales	T	COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
k59_1601637_2	159087.Daro_3330	1.13e-28	115.0	COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,2VH52@28216|Betaproteobacteria,2KUGH@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_2,DUF3971,DUF748
k59_1074531_1	709032.Sulku_1154	1.05e-68	222.0	COG4773@1|root,COG4773@2|Bacteria,1R8BS@1224|Proteobacteria,42M7T@68525|delta/epsilon subdivisions,2YS9H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	PFAM outer membrane porin	-	-	-	-	-	-	-	-	-	-	-	-	OprD
k59_1661051_1	159087.Daro_0177	1.05e-114	346.0	COG0365@1|root,COG0365@2|Bacteria,1MUX7@1224|Proteobacteria,2VKAN@28216|Betaproteobacteria,2KVQH@206389|Rhodocyclales	206389|Rhodocyclales	I	Acetyl-coenzyme A synthetase N-terminus	acsA	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k59_605042_2	1249480.B649_02000	2.66e-130	384.0	COG0642@1|root,COG2205@2|Bacteria,1Q179@1224|Proteobacteria,4313A@68525|delta/epsilon subdivisions,2YS9S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07645	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	-
k59_1777895_2	387093.SUN_0198	1.65e-118	340.0	COG1014@1|root,COG1014@2|Bacteria,1N12F@1224|Proteobacteria,42NN1@68525|delta/epsilon subdivisions,2YN1Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	pyruvate ferredoxin oxidoreductase	porC	-	1.2.7.1	ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
k59_489146_1	709032.Sulku_1191	1.44e-35	127.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,42NY7@68525|delta/epsilon subdivisions,2YNB3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	exodeoxyribonuclease III	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
k59_489146_2	2340.JV46_09110	1.05e-12	67.4	COG2110@1|root,COG2110@2|Bacteria,1RCWP@1224|Proteobacteria,1S3WJ@1236|Gammaproteobacteria,1J689@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	phosphatase homologous to the C-terminal domain of histone macroH2A1	ymdB	GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005515,GO:0008150,GO:0008428,GO:0009892,GO:0010605,GO:0016787,GO:0019213,GO:0019219,GO:0019222,GO:0019899,GO:0030234,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0043086,GO:0043900,GO:0044092,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0061463,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:1900190,GO:1900231	-	-	-	-	-	-	-	-	-	-	Macro
k59_191738_1	1537917.JU82_08580	1.41e-48	158.0	COG2863@1|root,COG2863@2|Bacteria,1PG8Y@1224|Proteobacteria,42VJJ@68525|delta/epsilon subdivisions,2YQGV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
k59_897826_1	1304883.KI912532_gene1689	4.14e-74	238.0	COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,1MV37@1224|Proteobacteria,2VJ21@28216|Betaproteobacteria,2KVJ8@206389|Rhodocyclales	206389|Rhodocyclales	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	3.1.4.17	ko:K01120	ko00230,map00230	-	R00191,R01234	RC00296	ko00000,ko00001,ko01000	-	-	-	FHA,GAF,HD,HD_5
k59_367664_1	1304883.KI912532_gene2321	2.04e-139	426.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,2VI7M@28216|Betaproteobacteria,2KVGD@206389|Rhodocyclales	206389|Rhodocyclales	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_1485379_1	153948.NAL212_0789	7.03e-56	188.0	COG2850@1|root,COG2850@2|Bacteria,1MW30@1224|Proteobacteria,2VH3D@28216|Betaproteobacteria,372A3@32003|Nitrosomonadales	28216|Betaproteobacteria	S	A domain family that is part of the cupin metalloenzyme superfamily.	ycfD	-	1.14.11.47	ko:K18850	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Cupin_4
k59_1428631_1	1537917.JU82_11210	3.81e-161	467.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,42MGF@68525|delta/epsilon subdivisions,2YN0E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the UbiD family	menA	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0396	UbiD
k59_1661121_1	709032.Sulku_0398	3.69e-54	171.0	COG0023@1|root,COG0023@2|Bacteria,1Q2ID@1224|Proteobacteria,42VSB@68525|delta/epsilon subdivisions,2YQ8F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Translation initiation factor SUI1	-	-	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
k59_1661121_3	869209.Tresu_0890	9.78e-05	45.4	2DBB6@1|root,2Z85M@2|Bacteria,2J6WN@203691|Spirochaetes	203691|Spirochaetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_73069_1	709032.Sulku_1359	9.81e-94	287.0	2AJGC@1|root,31A2T@2|Bacteria,1Q4TA@1224|Proteobacteria,42ZUH@68525|delta/epsilon subdivisions,2YRV9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_840455_1	709032.Sulku_0054	1.18e-127	379.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,42M3S@68525|delta/epsilon subdivisions,2YN4P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	GTP-binding protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
k59_1601729_1	159087.Daro_0010	2.81e-43	149.0	COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,2VIZ3@28216|Betaproteobacteria,2KUJJ@206389|Rhodocyclales	206389|Rhodocyclales	H	Belongs to the prokaryotic GSH synthase family	gshB	-	6.3.2.3	ko:K01920	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00497,R10994	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	GSH-S_ATP,GSH-S_N
k59_1601729_2	159087.Daro_0011	6.91e-207	579.0	COG0342@1|root,COG0342@2|Bacteria,1MVFS@1224|Proteobacteria,2VHD9@28216|Betaproteobacteria,2KUNH@206389|Rhodocyclales	206389|Rhodocyclales	U	glutamate--cysteine ligase	-	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	GshA
k59_1428660_1	1537917.JU82_03860	6.25e-101	296.0	COG1926@1|root,COG1926@2|Bacteria,1RAG8@1224|Proteobacteria,42N60@68525|delta/epsilon subdivisions,2YMCU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	phosphoribosyltransferase	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
k59_136861_1	1304284.L21TH_0141	2.05e-71	231.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,248HZ@186801|Clostridia,36DR5@31979|Clostridiaceae	186801|Clostridia	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,PG_binding_1,Peptidase_S41
k59_73077_1	1537917.JU82_09690	3.5e-11	63.2	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42S84@68525|delta/epsilon subdivisions,2YPD4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_8,dCache_3
k59_1629117_1	1249480.B649_03245	6.52e-74	228.0	COG2204@1|root,COG2204@2|Bacteria,1QUIV@1224|Proteobacteria,42M4N@68525|delta/epsilon subdivisions,2YMIT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_1629117_2	709032.Sulku_0653	9.74e-34	125.0	COG2046@1|root,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,42NAI@68525|delta/epsilon subdivisions,2YME3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	sulfate adenylyltransferase	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
k59_390833_1	1537917.JU82_06375	1.02e-92	275.0	COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,42N4V@68525|delta/epsilon subdivisions,2YN04@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the pseudouridine synthase RluA family	rluA	-	5.4.99.23,5.4.99.24	ko:K06179,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
k59_1333157_1	1304883.KI912532_gene278	4.17e-75	229.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,2VJS2@28216|Betaproteobacteria,2KW6H@206389|Rhodocyclales	206389|Rhodocyclales	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
k59_1333157_2	159087.Daro_3587	2.26e-20	85.1	COG1225@1|root,COG1225@2|Bacteria,1R9YF@1224|Proteobacteria,2VN9B@28216|Betaproteobacteria,2KW4T@206389|Rhodocyclales	206389|Rhodocyclales	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
k59_1100968_1	709032.Sulku_0625	2.93e-33	121.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,43B2E@68525|delta/epsilon subdivisions,2YN33@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	peptidylprolyl isomerase	peb4	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
k59_96365_1	709032.Sulku_0425	7.84e-91	278.0	COG0457@1|root,COG0457@2|Bacteria,1MXK4@1224|Proteobacteria,42PK9@68525|delta/epsilon subdivisions,2YNXX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
k59_1283478_1	1485544.JQKP01000015_gene2061	4.67e-55	181.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,2VJ6C@28216|Betaproteobacteria,44VCA@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k59_1283478_2	580332.Slit_1502	2.21e-28	111.0	2CG46@1|root,2Z7W3@2|Bacteria,1NFW3@1224|Proteobacteria,2VN3X@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1578161_1	159087.Daro_3576	8.08e-82	260.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2VMTA@28216|Betaproteobacteria,2M00C@206389|Rhodocyclales	206389|Rhodocyclales	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctM,DctQ
k59_453218_1	95619.PM1_0222540	6.99e-11	69.3	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1QTVB@1224|Proteobacteria,1RYDJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	pedS1	-	2.7.13.3	ko:K20975	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_4,PAS_7,PAS_8,Response_reg
k59_1100995_1	709032.Sulku_1282	1.21e-101	320.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2YNMM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.6,3.6.3.8	ko:K01535,ko:K01537	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.3.2,3.A.3.3	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
k59_1333215_1	1537917.JU82_10840	1.18e-121	356.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42N1P@68525|delta/epsilon subdivisions,2YP3M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	COG0436 Aspartate tyrosine aromatic aminotransferase	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_1283498_2	387092.NIS_1578	6.56e-16	78.2	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,42MZZ@68525|delta/epsilon subdivisions,2YMM3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	molybdopterin biosynthesis	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
k59_634517_1	1304883.KI912532_gene1963	1.5e-111	329.0	COG3063@1|root,COG3063@2|Bacteria,1MXPC@1224|Proteobacteria,2VNC8@28216|Betaproteobacteria,2KW79@206389|Rhodocyclales	206389|Rhodocyclales	NU	type 4 pilus biogenesis protein	pilF	-	-	ko:K02656	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	TPR_16,TPR_2,TPR_8
k59_634517_2	159087.Daro_2988	1.44e-43	151.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,2VIBN@28216|Betaproteobacteria,2KVXU@206389|Rhodocyclales	206389|Rhodocyclales	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
k59_39864_1	1537917.JU82_02775	1.43e-81	248.0	COG1521@1|root,COG1521@2|Bacteria,1PZXA@1224|Proteobacteria,42RA8@68525|delta/epsilon subdivisions,2YP14@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
k59_96403_1	709032.Sulku_1935	1.75e-156	442.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,42NMR@68525|delta/epsilon subdivisions,2YN8M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k59_634524_1	1249480.B649_04415	2.09e-61	199.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,42N83@68525|delta/epsilon subdivisions,2YTKP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	COG0842 ABC-type multidrug transport system, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
k59_634524_2	1249480.B649_04420	3.22e-29	112.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42MV1@68525|delta/epsilon subdivisions,2YTEK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	COG1131 ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_39881_1	1165841.SULAR_05483	5.55e-74	240.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2YMMT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_390901_1	159087.Daro_3442	1.21e-51	167.0	COG1272@1|root,COG1272@2|Bacteria,1PGRH@1224|Proteobacteria,2VJR4@28216|Betaproteobacteria,2KXVY@206389|Rhodocyclales	206389|Rhodocyclales	S	Haemolysin-III related	-	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
k59_738731_1	1249480.B649_07280	9.89e-119	352.0	COG2199@1|root,COG3706@2|Bacteria,1Q5A3@1224|Proteobacteria,430W0@68525|delta/epsilon subdivisions,2YRZB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_1510397_1	709032.Sulku_0019	1.9e-153	445.0	COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,42RCJ@68525|delta/epsilon subdivisions,2YNX9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG4775 Outer membrane protein protective antigen OMA87	-	-	-	ko:K07278	-	-	-	-	ko00000,ko02000	1.B.33.2.4	-	-	Bac_surface_Ag,POTRA
k59_1869411_2	709032.Sulku_0086	6.23e-23	92.8	COG0760@1|root,COG0760@2|Bacteria	2|Bacteria	O	peptidyl-prolyl cis-trans isomerase activity	surA	-	5.2.1.8	ko:K03769,ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,SurA_N,SurA_N_2,SurA_N_3
k59_516468_1	1537917.JU82_07845	1.4e-58	202.0	COG0755@1|root,COG1333@1|root,COG0755@2|Bacteria,COG1333@2|Bacteria,1RG0A@1224|Proteobacteria,42N37@68525|delta/epsilon subdivisions,2YMXW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Cytochrome c biogenesis protein	ccsBA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
k59_390924_1	709032.Sulku_0529	1.96e-100	311.0	COG0726@1|root,COG1649@1|root,COG0726@2|Bacteria,COG1649@2|Bacteria,1MWR2@1224|Proteobacteria,43AG1@68525|delta/epsilon subdivisions,2YT1V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Hypothetical glycosyl hydrolase family 13	-	-	-	ko:K11931	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000	-	-	-	GHL13,Polysacc_deac_1
k59_1869423_2	709032.Sulku_1739	1.49e-40	149.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2YRKW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0474 Cation transport ATPase	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
k59_863537_1	1249480.B649_09220	1.52e-128	385.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,42M2T@68525|delta/epsilon subdivisions,2YMF5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	ATP-dependent CLP protease ATP-binding subunit	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_1510440_1	1537917.JU82_03135	8.27e-68	221.0	COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,42MPN@68525|delta/epsilon subdivisions,2YMHV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Flagellar basal body protein	flgE	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bb_rod,Flg_bbr_C
k59_1510440_2	1537917.JU82_03140	2.06e-77	236.0	COG1843@1|root,COG1843@2|Bacteria,1PQS2@1224|Proteobacteria,42TAQ@68525|delta/epsilon subdivisions,2YPFZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Required for flagellar hook formation. May act as a scaffolding protein	flgD	-	-	ko:K02389	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgD,FlgD_ig
k59_924955_1	1121004.ATVC01000028_gene106	6.78e-34	136.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2VH4I@28216|Betaproteobacteria,2KQC9@206351|Neisseriales	206351|Neisseriales	L	DNA helicase	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_989150_1	159087.Daro_2450	1.58e-96	289.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,2VH97@28216|Betaproteobacteria,2KVRT@206389|Rhodocyclales	206389|Rhodocyclales	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
k59_697888_1	880073.Calab_3187	6.41e-08	59.7	COG4591@1|root,COG4591@2|Bacteria,2NQKW@2323|unclassified Bacteria	2|Bacteria	M	MacB-like periplasmic core domain	VPA0558	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
k59_220807_1	1349822.NSB1T_01230	2.73e-64	203.0	COG0543@1|root,COG0543@2|Bacteria,4NJ0I@976|Bacteroidetes,2FNBW@200643|Bacteroidia,22WH8@171551|Porphyromonadaceae	976|Bacteroidetes	C	Ferredoxin-NADP reductase	gltD	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
k59_516522_1	1537917.JU82_09715	2.25e-172	512.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,42MWW@68525|delta/epsilon subdivisions,2YMMH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_863575_1	748247.AZKH_4501	1.06e-52	186.0	COG4678@1|root,COG4678@2|Bacteria	2|Bacteria	-	-	traG	-	-	ko:K12056	-	-	-	-	ko00000,ko02044	3.A.7.11.1	-	-	TraG_N
k59_697901_2	709032.Sulku_0641	3.86e-36	129.0	COG3301@1|root,COG3301@2|Bacteria,1QSRQ@1224|Proteobacteria,42PAY@68525|delta/epsilon subdivisions,2YN5Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
k59_1101128_1	1537917.JU82_05875	1.83e-62	202.0	COG2200@1|root,COG2200@2|Bacteria,1PDZY@1224|Proteobacteria,42R3Q@68525|delta/epsilon subdivisions,2YP1E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL
k59_1803159_1	553174.HMPREF0659_A5523	2.6e-09	56.2	COG0716@1|root,COG0716@2|Bacteria,4NQ9B@976|Bacteroidetes,2FN7V@200643|Bacteroidia	976|Bacteroidetes	C	Low-potential electron donor to a number of redox enzymes	fldA	-	-	ko:K03839	-	-	-	-	ko00000	-	-	-	Flavodoxin_1
k59_1689323_1	1249480.B649_10970	8.04e-96	297.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,42KZC@68525|delta/epsilon subdivisions,2YM82@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
k59_700551_2	1249480.B649_01185	8.59e-127	363.0	COG1143@1|root,COG1143@2|Bacteria,1MZJF@1224|Proteobacteria,42M7S@68525|delta/epsilon subdivisions,2YNEG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
k59_866257_1	715451.ambt_06205	2.61e-76	238.0	2EIYW@1|root,33CQ3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_992338_1	522306.CAP2UW1_1286	1.44e-22	90.9	COG2703@1|root,COG2703@2|Bacteria	2|Bacteria	P	oxygen carrier activity	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	GGDEF,Guanylate_cyc,Hemerythrin,NIT
k59_700573_1	1537917.JU82_06585	5.65e-61	192.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,1MW67@1224|Proteobacteria,42SGH@68525|delta/epsilon subdivisions,2YNQD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Histidine biosynthesis bifunctional protein hisIE	hisI	-	3.5.4.19,3.6.1.31	ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH,PRA-PH
k59_280256_1	563040.Saut_0847	1.02e-72	243.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YMMN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1689382_1	1249480.B649_10585	9.39e-42	150.0	COG4972@1|root,COG4972@2|Bacteria,1PZTK@1224|Proteobacteria,42R44@68525|delta/epsilon subdivisions,2YP2H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Pilus assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1396554_1	1165841.SULAR_09959	2.77e-104	309.0	COG4121@1|root,COG4121@2|Bacteria,1Q8T8@1224|Proteobacteria,42RAP@68525|delta/epsilon subdivisions,2YP3B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_30
k59_394464_1	89187.ISM_01565	5.37e-08	56.6	COG0784@1|root,COG1595@1|root,COG0784@2|Bacteria,COG1595@2|Bacteria,1MX3Y@1224|Proteobacteria,2TT2R@28211|Alphaproteobacteria,46NXQ@74030|Roseovarius	28211|Alphaproteobacteria	T	response regulator	phyR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Sigma70_r4_2
k59_280286_1	159087.Daro_0926	5.43e-87	271.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VNJW@28216|Betaproteobacteria,2KW08@206389|Rhodocyclales	206389|Rhodocyclales	NT	Methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
k59_1632324_1	933262.AXAM01000127_gene1028	1.8e-87	269.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,42MV4@68525|delta/epsilon subdivisions,2WKHZ@28221|Deltaproteobacteria,2MI2I@213118|Desulfobacterales	28221|Deltaproteobacteria	F	PFAM AICARFT IMPCHase bienzyme	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
k59_812691_1	643562.Daes_2391	4.6e-22	97.4	COG4228@1|root,COG4228@2|Bacteria,1R4HU@1224|Proteobacteria,42Y6H@68525|delta/epsilon subdivisions,2WUJZ@28221|Deltaproteobacteria,2MAWZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	DNA circulation	-	-	-	-	-	-	-	-	-	-	-	-	DNA_circ_N
k59_167042_1	1026882.MAMP_02497	9.67e-52	180.0	COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,1RN9V@1236|Gammaproteobacteria,460AS@72273|Thiotrichales	72273|Thiotrichales	C	radical SAM protein YgiQ	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
k59_280300_1	1537917.JU82_05810	3.57e-149	434.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MHP@68525|delta/epsilon subdivisions,2YN92@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k59_1396589_1	159087.Daro_2727	4.98e-111	343.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,2VHYF@28216|Betaproteobacteria,2KVIZ@206389|Rhodocyclales	206389|Rhodocyclales	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_741326_2	159087.Daro_3850	1.86e-59	191.0	COG0631@1|root,COG0631@2|Bacteria,1MVE7@1224|Proteobacteria,2VIAV@28216|Betaproteobacteria,2KUHY@206389|Rhodocyclales	206389|Rhodocyclales	T	COG0631 Serine threonine protein phosphatase	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
k59_1396591_1	1249480.B649_01435	4.51e-50	164.0	2AIWS@1|root,319ED@2|Bacteria,1Q2HE@1224|Proteobacteria,42VQ7@68525|delta/epsilon subdivisions,2YQ77@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1396597_1	159087.Daro_2707	1.82e-98	298.0	COG1232@1|root,COG1232@2|Bacteria,1NQUH@1224|Proteobacteria,2VJV1@28216|Betaproteobacteria,2KVAB@206389|Rhodocyclales	206389|Rhodocyclales	H	squalene-associated FAD-dependent desaturase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
k59_1632357_1	709032.Sulku_1440	3.52e-77	231.0	COG1832@1|root,COG1832@2|Bacteria,1N03D@1224|Proteobacteria,42TZA@68525|delta/epsilon subdivisions,2YPC1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	CoA-binding protein	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
k59_700661_1	1304883.KI912532_gene3147	6.58e-35	131.0	COG3087@1|root,COG3087@2|Bacteria,1RCA5@1224|Proteobacteria,2VTK8@28216|Betaproteobacteria,2KWEX@206389|Rhodocyclales	206389|Rhodocyclales	D	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
k59_280370_1	977880.RALTA_A0966	6.93e-107	322.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,2VIGJ@28216|Betaproteobacteria,1K30M@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PFAM HI0933 family protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
k59_700665_2	438482.A4ZRB9_9CAUD	6.8e-29	117.0	4QBAU@10239|Viruses,4QW8E@35237|dsDNA viruses  no RNA stage,4QPEP@28883|Caudovirales,4QNY1@10744|Podoviridae	10744|Podoviridae	S	viral capsid assembly	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_700665_4	1220601.L7TJ79_9CAUD	1.46e-184	533.0	4QCM5@10239|Viruses,4QVZY@35237|dsDNA viruses  no RNA stage,4QQFH@28883|Caudovirales	28883|Caudovirales	S	Bacteriophage head to tail connecting protein	-	GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019028,GO:0019058,GO:0019068,GO:0019072,GO:0019073,GO:0032991,GO:0044403,GO:0044419,GO:0044423,GO:0046798,GO:0051704	-	-	-	-	-	-	-	-	-	-	-
k59_582445_1	1537917.JU82_07250	9.87e-104	313.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,42M04@68525|delta/epsilon subdivisions,2YMAR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
k59_582445_2	709032.Sulku_0936	5.94e-40	146.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42M01@68525|delta/epsilon subdivisions,2YMF7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	ABC transporter	msbA	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
k59_812771_1	1249480.B649_03965	8.47e-37	142.0	COG1033@1|root,COG1033@2|Bacteria	2|Bacteria	S	growth of symbiont in host cell	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_582456_1	765911.Thivi_0641	3.17e-27	110.0	COG0189@1|root,COG0189@2|Bacteria,1NNP5@1224|Proteobacteria,1RRUB@1236|Gammaproteobacteria,1WW74@135613|Chromatiales	135613|Chromatiales	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_582456_2	1123518.ARWI01000001_gene1323	3.58e-82	247.0	COG0503@1|root,COG0503@2|Bacteria,1MVZ6@1224|Proteobacteria,1S2N9@1236|Gammaproteobacteria,460RE@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
k59_637621_1	709032.Sulku_1433	9.92e-54	180.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,42M5C@68525|delta/epsilon subdivisions,2YM7M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	lytic murein transglycosylase	mltD	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
k59_637621_2	1249480.B649_05960	3.19e-23	94.7	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,42MMS@68525|delta/epsilon subdivisions,2YMA2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	hydrolase, TatD	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
k59_519285_1	90814.KL370891_gene875	4.42e-14	73.9	COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,1RPWB@1236|Gammaproteobacteria,460WQ@72273|Thiotrichales	72273|Thiotrichales	S	Belongs to the GcvT family	-	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
k59_1072509_1	1249480.B649_03080	3.23e-48	154.0	COG2944@1|root,COG2944@2|Bacteria,1Q2M2@1224|Proteobacteria,42VXE@68525|delta/epsilon subdivisions,2YQ6V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
k59_1837814_1	1454004.AW11_01938	6.57e-77	240.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,2VI9P@28216|Betaproteobacteria,1KPPY@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
k59_1837814_2	159087.Daro_0604	9.54e-67	205.0	COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,2VR9P@28216|Betaproteobacteria,2KWBU@206389|Rhodocyclales	206389|Rhodocyclales	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
k59_838371_1	563040.Saut_1275	6.92e-25	105.0	COG2194@1|root,COG2194@2|Bacteria,1MWS7@1224|Proteobacteria,42MI1@68525|delta/epsilon subdivisions,2YMPQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Sulfatase	eptA	-	2.7.8.43	ko:K03760	ko01503,map01503	M00722	R11555,R11556,R11557	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DUF1705,Sulfatase
k59_486957_1	159087.Daro_1782	4.81e-78	234.0	COG1763@1|root,COG1763@2|Bacteria,1RD3Q@1224|Proteobacteria,2VSIP@28216|Betaproteobacteria,2KWDE@206389|Rhodocyclales	206389|Rhodocyclales	H	molybdopterin-guanine dinucleotide biosynthesis protein	-	-	-	ko:K03753	-	-	-	-	ko00000	-	-	-	MobB
k59_1717351_1	1165841.SULAR_03472	1.09e-87	269.0	COG0387@1|root,COG0387@2|Bacteria,1N1MR@1224|Proteobacteria,42MUQ@68525|delta/epsilon subdivisions,2YMUB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Sodium calcium exchanger membrane	-	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
k59_663923_1	159087.Daro_3725	5.8e-92	287.0	COG0699@1|root,COG0699@2|Bacteria,1MXBK@1224|Proteobacteria,2VKA1@28216|Betaproteobacteria,2KUHM@206389|Rhodocyclales	206389|Rhodocyclales	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
k59_838392_1	709032.Sulku_0837	2.99e-45	149.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,42RNC@68525|delta/epsilon subdivisions,2YPBE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL,UPF0547
k59_895906_1	709032.Sulku_0823	2.33e-90	280.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,42MW6@68525|delta/epsilon subdivisions,2YNJR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	potassium channel protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans,Ion_trans_2,TrkA_C,TrkA_N
k59_1717368_1	1249480.B649_05830	8.33e-66	204.0	2AJ4F@1|root,319NZ@2|Bacteria,1Q3DH@1224|Proteobacteria,42X57@68525|delta/epsilon subdivisions,2YQQ1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1717368_2	709032.Sulku_1450	4.93e-41	140.0	2AI6H@1|root,318KU@2|Bacteria,1Q0KF@1224|Proteobacteria,42S88@68525|delta/epsilon subdivisions,2YP9S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_663945_1	1123256.KB907934_gene2403	3.59e-32	115.0	2AQ99@1|root,31FF5@2|Bacteria,1QCYT@1224|Proteobacteria,1T8SX@1236|Gammaproteobacteria,1XB6T@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1717370_1	1249480.B649_04710	7.92e-115	340.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42MGY@68525|delta/epsilon subdivisions,2YN2P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Glutamate synthase	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2,Pyr_redox_3
k59_603100_1	709032.Sulku_0059	8.08e-84	251.0	COG1714@1|root,COG1714@2|Bacteria,1N2TA@1224|Proteobacteria	1224|Proteobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
k59_1837860_1	1249480.B649_11660	2.04e-71	224.0	COG2956@1|root,COG2956@2|Bacteria,1QUIS@1224|Proteobacteria,42M7G@68525|delta/epsilon subdivisions,2YMKN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_7,TPR_8
k59_1251036_1	709032.Sulku_0739	5.87e-75	244.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2YN6Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DNA mismatch repair MutS family	-	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_III,MutS_V
k59_663955_1	1000565.METUNv1_02133	7.28e-72	234.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,2VHI9@28216|Betaproteobacteria,2KUN3@206389|Rhodocyclales	206389|Rhodocyclales	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_4,Toprim_N,zf-CHC2
k59_956134_1	1537917.JU82_09960	3.64e-98	293.0	COG4974@1|root,COG4974@2|Bacteria,1QU6A@1224|Proteobacteria,42RBN@68525|delta/epsilon subdivisions,2YP23@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_1544243_1	159087.Daro_2398	6.53e-66	216.0	COG3206@1|root,COG3206@2|Bacteria,1MVBX@1224|Proteobacteria,2VMDA@28216|Betaproteobacteria,2KUAM@206389|Rhodocyclales	206389|Rhodocyclales	M	Polysaccharide chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
k59_663990_1	1249480.B649_06150	1.32e-130	387.0	COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,42Q2M@68525|delta/epsilon subdivisions,2YNQQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG0155 Sulfite reductase, beta subunit (hemoprotein)	-	-	1.7.7.1	ko:K00366	ko00910,ko01120,map00910,map01120	M00531	R00790	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
k59_425653_1	709032.Sulku_0533	5.01e-35	120.0	COG3514@1|root,COG3514@2|Bacteria,1NAV1@1224|Proteobacteria,42XPB@68525|delta/epsilon subdivisions,2YQ8M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	BrnA antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnA_antitoxin,CopG_antitoxin
k59_425653_2	1397284.AYMN01000122_gene931	6.64e-15	79.3	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1RWPN@1236|Gammaproteobacteria,4023P@613|Serratia	1236|Gammaproteobacteria	T	Histidine Phosphotransfer domain	-	-	2.7.13.3	ko:K07678	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,PAS_7,Response_reg
k59_15529_1	709032.Sulku_2201	4.3e-129	373.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,42N1I@68525|delta/epsilon subdivisions,2YMA0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome	ccpA	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
k59_1365031_2	709032.Sulku_0507	3.95e-56	181.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,42MU5@68525|delta/epsilon subdivisions,2YM85@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_N
k59_15530_1	202955.BBND01000005_gene319	6.83e-43	159.0	COG4772@1|root,COG4772@2|Bacteria,1QVCH@1224|Proteobacteria,1T302@1236|Gammaproteobacteria,3NKUZ@468|Moraxellaceae	1236|Gammaproteobacteria	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_487044_1	1249480.B649_04405	1.94e-55	174.0	COG1959@1|root,COG1959@2|Bacteria,1N7JE@1224|Proteobacteria,42UAE@68525|delta/epsilon subdivisions,2YPWZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
k59_487044_2	709032.Sulku_1061	1.92e-99	295.0	COG0007@1|root,COG0007@2|Bacteria,1MUI0@1224|Proteobacteria,42MCB@68525|delta/epsilon subdivisions,2YR78@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	-	-	2.1.1.107	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03194	RC00003,RC00871	ko00000,ko00001,ko00002,ko01000	-	-	-	TP_methylase
k59_1251101_1	159087.Daro_0966	9.11e-51	177.0	COG2804@1|root,COG3437@1|root,COG2804@2|Bacteria,COG3437@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,2KVIS@206389|Rhodocyclales	206389|Rhodocyclales	NU	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Response_reg,T2SSE,T2SSE_N
k59_1251101_2	159087.Daro_0967	1.62e-67	218.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VPGG@28216|Betaproteobacteria,2KYCK@206389|Rhodocyclales	206389|Rhodocyclales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_838467_1	1132855.KB913035_gene885	4.37e-35	142.0	COG0642@1|root,COG2203@1|root,COG3829@1|root,COG5002@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria,2KNFH@206350|Nitrosomonadales	206350|Nitrosomonadales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
k59_1072619_1	1120931.KB893936_gene121	1.99e-11	65.9	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1Y77N@135625|Pasteurellales	135625|Pasteurellales	T	Aerobic respiration control sensor protein	arcB	-	2.7.13.3	ko:K07648	ko02020,ko02026,map02020,map02026	M00456	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
k59_1253536_1	709032.Sulku_0053	8.32e-116	342.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,42NU0@68525|delta/epsilon subdivisions,2YN8B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM HI0933 family protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
k59_308742_2	1537917.JU82_08960	7.8e-77	231.0	2BMN0@1|root,32G77@2|Bacteria,1Q0X8@1224|Proteobacteria,42SM0@68525|delta/epsilon subdivisions,2YPGW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_308742_3	929558.SMGD1_2397	9.21e-67	219.0	COG0642@1|root,COG4753@1|root,COG2205@2|Bacteria,COG4753@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	3.1.3.3,4.6.1.1	ko:K01768,ko:K07315	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	EAL,Guanylate_cyc,HATPase_c,HisKA,Pkinase,Response_reg,SpoIIE
k59_252262_1	1537917.JU82_07215	4.14e-35	128.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,42NJ0@68525|delta/epsilon subdivisions,2YM9A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
k59_1253564_1	203119.Cthe_3052	9.51e-84	286.0	COG3055@1|root,COG3209@1|root,COG3055@2|Bacteria,COG3209@2|Bacteria,1TR8F@1239|Firmicutes,248C6@186801|Clostridia,3WNK4@541000|Ruminococcaceae	186801|Clostridia	M	YD repeat	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,RHS_repeat
k59_666483_1	395493.BegalDRAFT_0675	4.19e-06	50.8	COG2703@1|root,COG2703@2|Bacteria,1RK9A@1224|Proteobacteria,1SAZP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	hemerythrin-like metal-binding	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
k59_666483_2	1121004.ATVC01000010_gene1035	8.04e-56	187.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,2VIWB@28216|Betaproteobacteria,2KPH0@206351|Neisseriales	206351|Neisseriales	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
k59_1367216_1	1121035.AUCH01000006_gene730	2.73e-88	264.0	COG0765@1|root,COG0765@2|Bacteria,1MV3I@1224|Proteobacteria,2VIQB@28216|Betaproteobacteria,2KW71@206389|Rhodocyclales	206389|Rhodocyclales	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10002	ko02010,ko02020,map02010,map02020	M00230	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.19,3.A.1.3.4	-	-	BPD_transp_1
k59_1367216_2	460265.Mnod_4480	3.97e-18	81.3	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,2TQX2@28211|Alphaproteobacteria,1JR7I@119045|Methylobacteriaceae	28211|Alphaproteobacteria	E	PFAM ABC transporter	gltL	-	3.6.3.21	ko:K02028,ko:K09972,ko:K10004	ko02010,ko02020,map02010,map02020	M00230,M00232,M00236	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.17,3.A.1.3.18,3.A.1.3.19,3.A.1.3.4,3.A.1.3.7,3.A.1.3.8	-	-	ABC_tran
k59_427511_1	709032.Sulku_0931	1.53e-72	223.0	COG1028@1|root,COG1028@2|Bacteria,1MU73@1224|Proteobacteria,42KZK@68525|delta/epsilon subdivisions,2YMUM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	IQ	dehydrogenase	hdhA	-	1.1.1.159	ko:K00076	ko00121,map00121	-	-	-	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
k59_427511_2	709032.Sulku_0932	4.28e-105	310.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,42M0X@68525|delta/epsilon subdivisions,2YN2X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
k59_1546708_2	709032.Sulku_0457	8.81e-96	280.0	COG1214@1|root,COG1214@2|Bacteria,1Q1J6@1224|Proteobacteria,42TUF@68525|delta/epsilon subdivisions,2YQ3R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	COG1214 Inactive homolog of metal-dependent proteases	tsaB	-	-	-	-	-	-	-	-	-	-	-	-
k59_1074853_1	1537917.JU82_08205	1.01e-110	335.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,42N1K@68525|delta/epsilon subdivisions,2YMYX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1g,tRNA_bind
k59_1074854_1	1249480.B649_11555	4.84e-38	129.0	2AJ5V@1|root,319QG@2|Bacteria,1Q3K7@1224|Proteobacteria,42XFR@68525|delta/epsilon subdivisions,2YQU7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1074854_2	709032.Sulku_2495	3.15e-47	161.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,42NR0@68525|delta/epsilon subdivisions,2YRAH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	ParA
k59_1778177_2	159087.Daro_4177	1.62e-53	187.0	COG4258@1|root,COG4258@2|Bacteria,1MU1E@1224|Proteobacteria,2VHXY@28216|Betaproteobacteria,2KVVT@206389|Rhodocyclales	206389|Rhodocyclales	S	MMPL family	-	-	-	-	-	-	-	-	-	-	-	-	MMPL
k59_137112_1	709032.Sulku_0324	6.23e-79	261.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2YMJS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,NIT,Response_reg
k59_1019203_1	1029823.AFIE01000093_gene2502	5.71e-14	77.8	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1RMZW@1236|Gammaproteobacteria,3NN17@468|Moraxellaceae	1236|Gammaproteobacteria	Q	Bacterial Ig-like domain (group 3)	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,VCBS
k59_666530_1	1123073.KB899243_gene654	1.86e-50	174.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,1X4ZP@135614|Xanthomonadales	135614|Xanthomonadales	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
k59_1840381_2	1537917.JU82_00200	3.58e-34	119.0	2AK43@1|root,31ATX@2|Bacteria,1Q64B@1224|Proteobacteria,432D7@68525|delta/epsilon subdivisions,2YSJA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1840381_3	709032.Sulku_1660	7.97e-12	66.2	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42N03@68525|delta/epsilon subdivisions,2YNMG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	PFAM Methyl-accepting chemotaxis protein (MCP) signaling domain	-	-	-	ko:K03406,ko:K05875	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,MCPsignal
k59_489524_1	1121396.KB893091_gene3496	6.29e-24	107.0	COG1042@1|root,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,42NTV@68525|delta/epsilon subdivisions,2WJTP@28221|Deltaproteobacteria,2MMHK@213118|Desulfobacterales	28221|Deltaproteobacteria	C	CoA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
k59_958377_1	387093.SUN_0117	5.51e-69	220.0	COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,42MBN@68525|delta/epsilon subdivisions,2YMCS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
k59_1546773_2	1249480.B649_05600	1.59e-58	197.0	COG0791@1|root,COG0791@2|Bacteria,1R45H@1224|Proteobacteria,42NS0@68525|delta/epsilon subdivisions,2YN06@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,N_NLPC_P60,Peptidase_M15_4,SH3_6,SH3_7
k59_489538_1	1537917.JU82_02705	2.62e-119	353.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,42M3N@68525|delta/epsilon subdivisions,2YMQ3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
k59_666562_2	1249480.B649_10630	4.41e-56	177.0	COG1815@1|root,COG1815@2|Bacteria,1PSBA@1224|Proteobacteria,42VSQ@68525|delta/epsilon subdivisions,2YPMD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body	-	-	-	ko:K02387	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod
k59_73281_1	497321.C664_10862	1.77e-13	68.9	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,2VH2M@28216|Betaproteobacteria,2KUDP@206389|Rhodocyclales	206389|Rhodocyclales	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
k59_73281_2	159087.Daro_0863	4.75e-143	404.0	COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,2VIJC@28216|Betaproteobacteria,2KUET@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
k59_1190960_1	1207055.C100_03230	2.33e-24	98.6	COG0252@1|root,COG0252@2|Bacteria,1RHAW@1224|Proteobacteria,2UFQ1@28211|Alphaproteobacteria,2K4ZM@204457|Sphingomonadales	204457|Sphingomonadales	EJ	Asparaginase, N-terminal	-	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
k59_1190960_2	1236542.BALM01000004_gene2404	7.99e-13	63.5	COG2350@1|root,COG2350@2|Bacteria,1MZ9Z@1224|Proteobacteria,1S8UC@1236|Gammaproteobacteria,2QC9E@267890|Shewanellaceae	1236|Gammaproteobacteria	S	PFAM YCII-related	yciI	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K05527,ko:K09780	-	-	-	-	ko00000,ko03000	-	-	-	YCII
k59_779095_1	709032.Sulku_1904	4.96e-108	323.0	COG1168@1|root,COG1168@2|Bacteria,1MY33@1224|Proteobacteria,42M6F@68525|delta/epsilon subdivisions,2YMXE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Aminotransferase, class I	patB	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_1428985_1	1249480.B649_07280	3.76e-77	245.0	COG2199@1|root,COG3706@2|Bacteria,1Q5A3@1224|Proteobacteria,430W0@68525|delta/epsilon subdivisions,2YRZB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_1485680_1	1123517.JOMR01000001_gene964	2.02e-43	161.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,45ZNT@72273|Thiotrichales	72273|Thiotrichales	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_1840447_1	1536773.R70331_11760	4.87e-07	52.8	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1VT9I@1239|Firmicutes,4HT43@91061|Bacilli,26W66@186822|Paenibacillaceae	91061|Bacilli	T	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,Response_reg
k59_1840447_2	1304885.AUEY01000029_gene2487	3.56e-22	101.0	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,42NK9@68525|delta/epsilon subdivisions,2X7E0@28221|Deltaproteobacteria,2MITZ@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07678	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Response_reg
k59_1306495_1	387093.SUN_1778	6.95e-93	277.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,42MTF@68525|delta/epsilon subdivisions,2YMZQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	involved in chromosome partitioning	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
k59_1661449_1	1537917.JU82_01600	2.89e-68	209.0	COG1815@1|root,COG1815@2|Bacteria,1PSBA@1224|Proteobacteria,42VSQ@68525|delta/epsilon subdivisions,2YPMD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body	-	-	-	ko:K02387	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod
k59_1429032_1	1249480.B649_02210	9.57e-89	276.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,42Q71@68525|delta/epsilon subdivisions,2YMSG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the 5'-nucleotidase family	soxB	-	3.1.3.6,3.1.4.16	ko:K01119,ko:K17224	ko00230,ko00240,ko00920,ko01100,ko01120,map00230,map00240,map00920,map01100,map01120	M00595	R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135,R10151	RC00078,RC00296,RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	-	-	-	5_nucleotid_C,Metallophos
k59_1840477_1	1172190.M947_11250	1.57e-58	189.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,42TAC@68525|delta/epsilon subdivisions,2YRI5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	COG2518 Protein-L-isoaspartate carboxylmethyltransferase	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
k59_1306509_1	580332.Slit_0022	1.47e-11	63.2	COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,2W9UD@28216|Betaproteobacteria,44V05@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Belongs to the RuBisCO large chain family	-	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
k59_1306509_2	1123401.JHYQ01000015_gene1399	2.14e-154	437.0	COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,1RN7C@1236|Gammaproteobacteria,461Q0@72273|Thiotrichales	72273|Thiotrichales	S	CbbQ/NirQ/NorQ C-terminal	-	-	-	ko:K04748	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	AAA_5,CbbQ_C
k59_1306509_3	1163617.SCD_n02852	1.91e-19	88.6	COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,2VJJW@28216|Betaproteobacteria	28216|Betaproteobacteria	P	von Willebrand factor, type A	cbbO2	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
k59_717713_1	1027273.GZ77_24160	4.88e-72	225.0	COG3384@1|root,COG3384@2|Bacteria,1MWNC@1224|Proteobacteria,1RPH7@1236|Gammaproteobacteria,1XI23@135619|Oceanospirillales	135619|Oceanospirillales	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	1.13.11.15	ko:K00455	ko00350,ko01120,ko01220,map00350,map01120,map01220	M00533	R03303	RC00643	ko00000,ko00001,ko00002,ko01000	-	-	-	LigB
k59_717713_2	1347087.CBYO010000016_gene2695	4.44e-16	73.6	COG3232@1|root,COG3232@2|Bacteria,1V8CK@1239|Firmicutes,4HIUF@91061|Bacilli	91061|Bacilli	E	5-carboxymethyl-2-hydroxymuconate isomerase	hpcD	-	5.3.3.10	ko:K01826	ko00350,ko01120,ko01220,map00350,map01120,map01220	M00533	R04379,R04482	RC01141,RC01162	ko00000,ko00001,ko00002,ko01000	-	-	-	CHMI
k59_1191049_1	1121921.KB898709_gene266	3.35e-135	403.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,1RMYE@1236|Gammaproteobacteria,2PN4R@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	J	Threonyl and Alanyl tRNA synthetase second additional domain	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
k59_1429095_1	1304883.KI912532_gene891	1.34e-47	164.0	2EFF1@1|root,3397W@2|Bacteria,1N9PW@1224|Proteobacteria,2VX4Q@28216|Betaproteobacteria,2KXE8@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_308883_1	1443113.LC20_01034	9.35e-39	148.0	COG0741@1|root,COG0741@2|Bacteria,1MW2T@1224|Proteobacteria,1RM9N@1236|Gammaproteobacteria,41D81@629|Yersinia	1236|Gammaproteobacteria	M	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division	mltC	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030313,GO:0031224,GO:0031225,GO:0031975,GO:0033554,GO:0034599,GO:0042221,GO:0042597,GO:0043170,GO:0044425,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0061783,GO:0070887,GO:0071236,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	ko:K08306	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	iG2583_1286.G2583_3622,iUMNK88_1353.UMNK88_3661	DUF3393,SLT
k59_549569_1	1304883.KI912532_gene278	3.95e-36	129.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,2VJS2@28216|Betaproteobacteria,2KW6H@206389|Rhodocyclales	206389|Rhodocyclales	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
k59_549569_2	1304883.KI912532_gene277	1.04e-91	281.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,2VGZV@28216|Betaproteobacteria,2KU63@206389|Rhodocyclales	206389|Rhodocyclales	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
k59_427672_1	159087.Daro_3777	4.3e-110	337.0	28J5I@1|root,2Z91C@2|Bacteria,1QVI2@1224|Proteobacteria,2VN9N@28216|Betaproteobacteria,2KV6Q@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF1302)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1302
k59_1075032_1	1537917.JU82_07440	6.67e-87	262.0	COG0515@1|root,COG0515@2|Bacteria,1R91D@1224|Proteobacteria,42XMS@68525|delta/epsilon subdivisions,2YT4X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KLT	Lipopolysaccharide kinase (Kdo/WaaP) family	-	-	-	-	-	-	-	-	-	-	-	-	Kdo
k59_1075032_2	1537917.JU82_07445	9.88e-38	133.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
k59_958506_2	1209072.ALBT01000052_gene554	4.44e-15	82.8	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,1RMW6@1236|Gammaproteobacteria,1FGEP@10|Cellvibrio	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4131)	ycaI	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
k59_1719533_1	1249480.B649_09370	6.21e-118	342.0	COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,42MES@68525|delta/epsilon subdivisions,2YMU9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
k59_1719533_2	1249480.B649_09375	6.99e-221	611.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,42M99@68525|delta/epsilon subdivisions,2YMR8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
k59_27193_2	1537917.JU82_02925	2.14e-47	163.0	2AIMJ@1|root,3193W@2|Bacteria,1Q1QU@1224|Proteobacteria,42U73@68525|delta/epsilon subdivisions,2YSXF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1088068_1	929558.SMGD1_1085	1.62e-42	152.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42NHE@68525|delta/epsilon subdivisions,2YMQ8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
k59_27194_1	1049564.TevJSym_bw00090	1.17e-80	263.0	COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,1RMNX@1236|Gammaproteobacteria,1J5D0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	KL	HELICc2	yoaA	GO:0003674,GO:0003824,GO:0004386,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008026,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0070035,GO:0071704,GO:0090304,GO:1901360	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,ResIII
k59_27194_2	1234364.AMSF01000034_gene312	1.76e-15	75.9	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,1RPYX@1236|Gammaproteobacteria,1X633@135614|Xanthomonadales	135614|Xanthomonadales	O	glycoprotease	-	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
k59_264518_1	709032.Sulku_0881	3.19e-133	402.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2YMAI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k59_682696_1	391615.ABSJ01000035_gene1009	1.23e-84	278.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,1J4ZQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_910088_2	1249480.B649_10195	1.25e-64	199.0	COG1399@1|root,COG1399@2|Bacteria,1Q1I8@1224|Proteobacteria,42TRP@68525|delta/epsilon subdivisions,2YQ23@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	metal-binding, possibly nucleic acid-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF177
k59_1790483_1	395493.BegalDRAFT_1634	1.83e-32	120.0	COG3907@1|root,COG3907@2|Bacteria,1MU4M@1224|Proteobacteria,1RQ2Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PAP2 (Acid phosphatase) superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
k59_1790483_2	1537917.JU82_02010	9.55e-51	168.0	COG3338@1|root,COG3338@2|Bacteria,1PEA6@1224|Proteobacteria,42RBG@68525|delta/epsilon subdivisions,2YP5T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	carbonic anhydrase	cah	-	4.2.1.1	ko:K01674	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Carb_anhydrase
k59_1673782_1	1537917.JU82_05585	4.44e-41	142.0	COG2005@1|root,COG3585@1|root,COG2005@2|Bacteria,COG3585@2|Bacteria,1P9SX@1224|Proteobacteria,42RG9@68525|delta/epsilon subdivisions,2YMVF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Transcriptional regulator, ModE family	modE	-	-	ko:K02019	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,TOBE
k59_1673782_2	1249480.B649_04930	5.86e-09	57.8	COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,42QWE@68525|delta/epsilon subdivisions,2YNG3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	ABC transporter, periplasmic molybdate-binding protein	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
k59_1445483_1	90813.JQMT01000001_gene583	3.3e-39	139.0	COG1651@1|root,COG1651@2|Bacteria,1RD39@1224|Proteobacteria,1S3U8@1236|Gammaproteobacteria,460JH@72273|Thiotrichales	72273|Thiotrichales	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	-	-	5.3.4.1	ko:K03981	-	-	-	-	ko00000,ko01000,ko02044,ko03110	3.A.7.11.1	-	-	DsbC_N,Thioredoxin_2
k59_852143_2	1249480.B649_03105	7.05e-33	114.0	2BSV5@1|root,32MYQ@2|Bacteria,1Q3GB@1224|Proteobacteria,42XA1@68525|delta/epsilon subdivisions,2YQPY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1203458_1	1304883.KI912532_gene720	1.99e-102	301.0	COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,2VI5G@28216|Betaproteobacteria,2KU7S@206389|Rhodocyclales	206389|Rhodocyclales	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
k59_1856453_1	159087.Daro_0316	2.7e-119	360.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,2VI3Q@28216|Betaproteobacteria,2KUP0@206389|Rhodocyclales	206389|Rhodocyclales	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_1673827_1	640081.Dsui_0018	3.1e-66	208.0	COG0730@1|root,COG0730@2|Bacteria,1R712@1224|Proteobacteria,2VIJA@28216|Betaproteobacteria,2KV6U@206389|Rhodocyclales	206389|Rhodocyclales	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k59_1203482_1	666681.M301_1749	1.27e-22	94.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,2VIM9@28216|Betaproteobacteria,2KM6N@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
k59_1203482_2	583345.Mmol_1583	8.95e-73	238.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,2VHR1@28216|Betaproteobacteria,2KM1R@206350|Nitrosomonadales	206350|Nitrosomonadales	J	TIGRFAM phenylalanyl-tRNA synthetase, beta subunit	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k59_1037148_1	1165841.SULAR_06788	6.44e-74	229.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,42MVM@68525|delta/epsilon subdivisions,2YMMR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxC
k59_1037148_2	1165841.SULAR_06793	4.84e-57	189.0	COG0739@1|root,COG0739@2|Bacteria,1NESH@1224|Proteobacteria,42MGB@68525|delta/epsilon subdivisions,2YMT7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_795307_1	1120999.JONM01000023_gene3157	7.35e-92	294.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2VIJE@28216|Betaproteobacteria,2KPRX@206351|Neisseriales	206351|Neisseriales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_852177_2	709032.Sulku_0582	7.74e-111	323.0	29VYJ@1|root,30HGQ@2|Bacteria,1Q33E@1224|Proteobacteria,42WQE@68525|delta/epsilon subdivisions,2YQMM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_852177_3	709032.Sulku_0581	1.04e-69	212.0	COG0816@1|root,COG0816@2|Bacteria,1RJ6T@1224|Proteobacteria,42UR4@68525|delta/epsilon subdivisions,2YSYJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
k59_852177_4	1249480.B649_02895	7.99e-104	313.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,42M6T@68525|delta/epsilon subdivisions,2YMJD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
k59_150922_1	1249480.B649_11270	7.44e-89	268.0	28M05@1|root,32SJ0@2|Bacteria,1N115@1224|Proteobacteria,42ZGF@68525|delta/epsilon subdivisions,2YRPD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1856470_1	709032.Sulku_0286	1.5e-65	204.0	COG1057@1|root,COG1057@2|Bacteria,1NG4J@1224|Proteobacteria,42P0F@68525|delta/epsilon subdivisions,2YQ32@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP1337	CTP_transf_like
k59_795311_1	1249480.B649_06420	3.07e-95	286.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,42N1C@68525|delta/epsilon subdivisions,2YMUA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
k59_1497141_1	159087.Daro_2173	2.4e-137	405.0	COG3519@1|root,COG3519@2|Bacteria,1MUY4@1224|Proteobacteria,2VHXS@28216|Betaproteobacteria,2KWBQ@206389|Rhodocyclales	206389|Rhodocyclales	S	Type VI secretion system, TssF	-	-	-	ko:K11896	-	M00334	-	-	ko00000,ko00002,ko02044	3.A.23.1	-	-	T6SS_TssF
k59_1380453_1	1249480.B649_00155	2.21e-133	392.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,42MDZ@68525|delta/epsilon subdivisions,2YMJR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaGprimase_HBD,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
k59_1380453_2	760154.Sulba_2284	7.71e-52	185.0	COG0840@1|root,COG4564@1|root,COG0840@2|Bacteria,COG4564@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2YMW5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,dCache_2
k59_910170_1	1249480.B649_02455	1.81e-140	400.0	COG1432@1|root,COG1432@2|Bacteria,1MX5C@1224|Proteobacteria,42QHV@68525|delta/epsilon subdivisions,2YNYV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
k59_1203503_2	497321.C664_04042	7.92e-14	73.6	COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,2VPB3@28216|Betaproteobacteria,2KVVY@206389|Rhodocyclales	206389|Rhodocyclales	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_4,TPR_8
k59_379336_2	1304883.KI912532_gene2584	3.02e-11	62.4	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,2VITX@28216|Betaproteobacteria,2KU9S@206389|Rhodocyclales	206389|Rhodocyclales	C	Cysteine-rich domain	-	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
k59_1790564_1	717773.Thicy_0089	1.55e-137	395.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,4604G@72273|Thiotrichales	72273|Thiotrichales	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k59_503771_1	745411.B3C1_18712	4.8e-194	559.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNSZ@1236|Gammaproteobacteria,1J4UF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_1445560_1	1249480.B649_01815	1.17e-58	181.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,42V9Q@68525|delta/epsilon subdivisions,2YQAF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	RNA-binding protein	rbpA	-	-	-	-	-	-	-	-	-	-	-	RRM_1
k59_265873_2	1537917.JU82_11210	1.83e-60	202.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,42MGF@68525|delta/epsilon subdivisions,2YN0E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the UbiD family	menA	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0396	UbiD
k59_441608_1	62928.azo3061	2.24e-145	444.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KY07@206389|Rhodocyclales	206389|Rhodocyclales	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF
k59_86007_1	1249480.B649_06080	5.17e-39	144.0	COG2984@1|root,COG2984@2|Bacteria,1PGQI@1224|Proteobacteria,43496@68525|delta/epsilon subdivisions,2YRIT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	ABC transporter substrate binding protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1151974_1	388051.AUFE01000029_gene5642	3.46e-45	167.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,1K044@119060|Burkholderiaceae	28216|Betaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	mdtC	-	-	ko:K03296,ko:K07789	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	2.A.6.2	-	-	ACR_tran
k59_1858195_1	709032.Sulku_1760	1.62e-96	302.0	COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,42NB2@68525|delta/epsilon subdivisions,2YMVN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
k59_1205119_1	314724.BT0057	5.5e-37	134.0	COG0057@1|root,COG0057@2|Bacteria,2J5AD@203691|Spirochaetes	203691|Spirochaetes	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k59_1205119_2	1121938.AUDY01000014_gene3431	4.59e-14	73.6	COG2390@1|root,COG2390@2|Bacteria,1TP62@1239|Firmicutes,4HAE6@91061|Bacilli,3NDGZ@45667|Halobacillus	91061|Bacilli	K	Putative sugar-binding domain	cggR	-	-	ko:K05311	-	-	-	-	ko00000,ko03000	-	-	-	Sugar-bind
k59_319209_1	159087.Daro_0266	1.45e-105	309.0	COG4122@1|root,COG4122@2|Bacteria,1QWFV@1224|Proteobacteria,2WGYC@28216|Betaproteobacteria,2KZPR@206389|Rhodocyclales	206389|Rhodocyclales	S	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1675203_1	1249480.B649_09120	3.45e-96	294.0	COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,42N4Y@68525|delta/epsilon subdivisions,2YNCE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase,Methyltransf_11,Methyltransf_31
k59_265960_1	159087.Daro_2172	1.98e-156	446.0	COG3520@1|root,COG3520@2|Bacteria,1MWVS@1224|Proteobacteria,2VIPW@28216|Betaproteobacteria,2KX6Y@206389|Rhodocyclales	206389|Rhodocyclales	S	Type VI secretion, TssG	-	-	-	ko:K11895	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_TssG
k59_380802_2	1537917.JU82_06535	3.97e-27	102.0	COG1985@1|root,COG1985@2|Bacteria	2|Bacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
k59_1039149_1	497321.C664_01255	9.22e-122	365.0	COG4383@1|root,COG4383@2|Bacteria,1MWNS@1224|Proteobacteria,2VJIH@28216|Betaproteobacteria,2KY6K@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF935)	-	-	-	-	-	-	-	-	-	-	-	-	DUF935
k59_1271736_1	929558.SMGD1_2858	3.99e-46	161.0	COG0665@1|root,COG0665@2|Bacteria,1Q0BQ@1224|Proteobacteria,42RXA@68525|delta/epsilon subdivisions,2YP66@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	COGs COG0665 Glycine D-amino acid oxidase (deaminating)	-	-	2.1.1.61	ko:K15461	-	-	R00601,R08702	RC00003,RC00053,RC00060,RC01483	ko00000,ko01000,ko03016	-	-	-	DAO
k59_567819_1	583345.Mmol_1995	6.41e-38	142.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,2VHPK@28216|Betaproteobacteria,2KKTQ@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Soluble lytic murein transglycosylase L domain	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,SLT_L
k59_567819_3	1132855.KB913035_gene638	6.97e-08	53.5	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,2VHI8@28216|Betaproteobacteria,2KKCT@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxC
k59_265978_1	1537917.JU82_05105	4.41e-22	97.1	COG3164@1|root,COG3164@2|Bacteria,1QUYX@1224|Proteobacteria,43CES@68525|delta/epsilon subdivisions,2YTC9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
k59_265978_2	709032.Sulku_2532	2.52e-11	63.2	COG2855@1|root,COG2855@2|Bacteria,1MVIP@1224|Proteobacteria,42P59@68525|delta/epsilon subdivisions,2YMPJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the UPF0324 family	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
k59_1616397_1	582744.Msip34_2408	2.68e-99	296.0	COG0697@1|root,COG0697@2|Bacteria,1NEYM@1224|Proteobacteria,2VPAG@28216|Betaproteobacteria,2KMJ2@206350|Nitrosomonadales	206350|Nitrosomonadales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_1319325_2	199310.c1025	6.73e-96	290.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,1RMEX@1236|Gammaproteobacteria,3XNJ5@561|Escherichia	1236|Gammaproteobacteria	O	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	GO:0000166,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	iPC815.YPO1374	Pyr_redox_2
k59_86114_2	1217652.F954_02867	3.1e-56	199.0	COG1783@1|root,COG1783@2|Bacteria,1R66A@1224|Proteobacteria,1RQFD@1236|Gammaproteobacteria,3NSTS@468|Moraxellaceae	1236|Gammaproteobacteria	S	Phage terminase large subunit	-	-	-	ko:K06909	-	-	-	-	ko00000	-	-	-	Terminase_3,Terminase_3C
k59_265989_1	1123325.JHUV01000008_gene654	9.41e-54	184.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	czcB	-	-	ko:K07798,ko:K15727	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1,8.A.1.2.1	-	-	HlyD_D23
k59_1089836_2	1537917.JU82_08655	0.000147	44.3	2C2VD@1|root,338G0@2|Bacteria,1P3HX@1224|Proteobacteria,42NM6@68525|delta/epsilon subdivisions,2YM9Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1447407_1	929558.SMGD1_2862	2.96e-90	286.0	COG4774@1|root,COG4774@2|Bacteria,1QV5G@1224|Proteobacteria	1224|Proteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_567842_2	1249480.B649_01215	5.37e-148	446.0	COG0457@1|root,COG0457@2|Bacteria,1QV1A@1224|Proteobacteria,42MIW@68525|delta/epsilon subdivisions,2YMDB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Paralysed flagella protein	pflA	-	-	-	-	-	-	-	-	-	-	-	TPR_21,TPR_6,TPR_8,YfiO
k59_1791946_1	1165841.SULAR_03757	6.97e-104	313.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2YNK4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
k59_567850_1	1249480.B649_07425	1.07e-79	244.0	COG2885@1|root,COG2885@2|Bacteria,1R8DG@1224|Proteobacteria,42NGC@68525|delta/epsilon subdivisions,2YN3X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the ompA family	cadF	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA
k59_152839_1	926550.CLDAP_29060	2.19e-79	246.0	COG1562@1|root,COG1562@2|Bacteria,2G6KD@200795|Chloroflexi	200795|Chloroflexi	I	PFAM Squalene phytoene synthase	crtB	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
k59_684675_1	387093.SUN_0561	9.95e-42	141.0	2AJX8@1|root,31AK8@2|Bacteria,1Q5T5@1224|Proteobacteria,431S9@68525|delta/epsilon subdivisions,2YSC4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_684675_2	387093.SUN_0560	1.88e-07	56.2	COG5049@1|root,COG5049@2|Bacteria,1PFK8@1224|Proteobacteria,42YJI@68525|delta/epsilon subdivisions,2YRCQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	ADL	5'-3' exoribonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1733838_1	555778.Hneap_1901	5.44e-25	97.4	COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,1S20I@1236|Gammaproteobacteria,1WXGS@135613|Chromatiales	135613|Chromatiales	E	TIGRFAM Acetolactate synthase, small subunit	-	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_5,ALS_ss_C
k59_1733838_2	317025.Tcr_0634	6.03e-71	229.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria,45ZVD@72273|Thiotrichales	72273|Thiotrichales	E	TIGRFAM Acetolactate synthase, large subunit, biosynthetic	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_266040_1	1249480.B649_03335	0.0	872.0	COG0074@1|root,COG0372@1|root,COG0074@2|Bacteria,COG0372@2|Bacteria,1MUGA@1224|Proteobacteria,42NI0@68525|delta/epsilon subdivisions,2YNKI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	ATP citrate synthase	-	-	2.3.3.8	ko:K15230	ko00020,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00720,map01100,map01110,map01120,map01130,map01200	M00173	R00352	RC00004,RC00067	ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt,Ligase_CoA
k59_911624_1	998674.ATTE01000001_gene178	3.44e-33	125.0	COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,1RPYF@1236|Gammaproteobacteria,461AJ@72273|Thiotrichales	72273|Thiotrichales	P	ABC 3 transport family	-	-	-	ko:K02075	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC-3
k59_1271854_2	1458275.AZ34_13105	1.39e-12	67.8	COG0007@1|root,COG0007@2|Bacteria,1MUI0@1224|Proteobacteria,2VICS@28216|Betaproteobacteria,4AAU2@80864|Comamonadaceae	28216|Betaproteobacteria	H	Belongs to the precorrin methyltransferase family	cysG	-	1.3.1.76,2.1.1.107,4.99.1.4	ko:K02302,ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03194,R03947	RC00003,RC00871,RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase
k59_1675314_1	519989.ECTPHS_07411	2.58e-72	234.0	COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,1RMC0@1236|Gammaproteobacteria,1WVV8@135613|Chromatiales	135613|Chromatiales	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.7	ko:K00383	ko00480,ko04918,map00480,map04918	-	R00094,R00115	RC00011	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
k59_380937_1	1165841.SULAR_08387	1.54e-106	316.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,42M0M@68525|delta/epsilon subdivisions,2YMCK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the SIS family. GutQ KpsF subfamily	kpsF	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
k59_622238_1	1121035.AUCH01000009_gene868	8.32e-99	305.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,2VHS3@28216|Betaproteobacteria,2KV81@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
k59_1733887_1	1123326.JFBL01000005_gene1118	7.46e-25	107.0	2AN97@1|root,32J0R@2|Bacteria,1PCA3@1224|Proteobacteria,42T7U@68525|delta/epsilon subdivisions,2YPPF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Flg_hook
k59_1616526_1	1249480.B649_09935	1.92e-82	255.0	COG0438@1|root,COG0438@2|Bacteria,1QFQQ@1224|Proteobacteria,42Q8D@68525|delta/epsilon subdivisions,2YMC5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Glycosyl transferases group 1	pglH1	-	2.4.1.292	ko:K17249	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
k59_1733891_1	1249480.B649_07020	1.34e-22	95.1	COG2223@1|root,COG2223@2|Bacteria,1MU27@1224|Proteobacteria,42PGA@68525|delta/epsilon subdivisions,2YMBC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG2223 Nitrate nitrite transporter	-	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1
k59_684782_1	159087.Daro_3477	1.54e-77	234.0	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,2VHGQ@28216|Betaproteobacteria,2KVJD@206389|Rhodocyclales	206389|Rhodocyclales	EH	anthranilate	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
k59_684782_2	159087.Daro_3480	4.91e-87	264.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,2VJ5G@28216|Betaproteobacteria,2KUAX@206389|Rhodocyclales	206389|Rhodocyclales	M	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
k59_319340_1	709032.Sulku_0528	2.05e-71	227.0	COG1215@1|root,COG1215@2|Bacteria,1MXG7@1224|Proteobacteria,42Q7W@68525|delta/epsilon subdivisions,2YQ1A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Glycosyl transferase family 21	-	-	-	ko:K11936	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.1.1.2,4.D.1.1.3	GT2	-	Glyco_tranf_2_3
k59_319340_2	1249480.B649_02625	4.46e-21	86.7	2E6EV@1|root,3312A@2|Bacteria,1N8Q0@1224|Proteobacteria,42WW1@68525|delta/epsilon subdivisions,2YRZ8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PgaD-like protein	-	-	-	ko:K11937	ko02026,map02026	-	-	-	ko00000,ko00001	-	-	-	PgaD
k59_911688_1	709032.Sulku_1390	6.14e-179	504.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,42KZM@68525|delta/epsilon subdivisions,2YMIC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
k59_1695564_1	709032.Sulku_0367	1.44e-81	249.0	COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,42MQQ@68525|delta/epsilon subdivisions,2YNAG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	dna polymerase iii	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_644108_1	870187.Thini_0783	3.85e-57	187.0	COG0500@1|root,COG2226@2|Bacteria,1RKQD@1224|Proteobacteria,1RZ3N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Pfam Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
k59_174263_2	1537917.JU82_09755	3.01e-36	135.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42P4R@68525|delta/epsilon subdivisions,2YM92@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	DUF3365,MCPsignal
k59_644118_1	1232410.KI421412_gene319	5.83e-26	110.0	COG0297@1|root,COG0366@1|root,COG0297@2|Bacteria,COG0366@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2WITI@28221|Deltaproteobacteria,43U7I@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Starch synthase catalytic domain	glgA-2	GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Alpha-amylase,Glyco_transf_5,Glycos_transf_1
k59_340381_1	1537917.JU82_02010	1.99e-48	162.0	COG3338@1|root,COG3338@2|Bacteria,1PEA6@1224|Proteobacteria,42RBG@68525|delta/epsilon subdivisions,2YP5T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	carbonic anhydrase	cah	-	4.2.1.1	ko:K01674	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Carb_anhydrase
k59_228298_1	709032.Sulku_1952	3.82e-41	148.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42UQ6@68525|delta/epsilon subdivisions,2YQ4D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	PAS fold	-	-	-	ko:K03776	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	PAS_3
k59_228298_2	1537917.JU82_00175	2.89e-31	117.0	COG0642@1|root,COG2205@2|Bacteria,1RK1D@1224|Proteobacteria,42R91@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_48304_1	679897.HMU02740	8.12e-25	103.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2YMHD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA helicase	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_524784_1	395494.Galf_1254	2.15e-87	268.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,2VHBR@28216|Betaproteobacteria,44VE3@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
k59_228302_1	1286093.C266_04329	6.92e-52	173.0	COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,2VI5Z@28216|Betaproteobacteria,1K1Y5@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	-	ko:K18336	ko00051,ko01120,map00051,map01120	-	R10691	RC00326,RC03236	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
k59_1695597_1	614083.AWQR01000047_gene3280	1.97e-26	113.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,4AA83@80864|Comamonadaceae	28216|Betaproteobacteria	T	Chemotaxis sensory transducer	-	-	-	ko:K03406,ko:K03776,ko:K05875	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,PAS_3
k59_1342841_1	56780.SYN_01331	6.15e-90	287.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,42MEQ@68525|delta/epsilon subdivisions,2WIPF@28221|Deltaproteobacteria,2MQYI@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Carbohydrate phosphorylase	-	-	2.4.1.1,2.4.1.11	ko:K00688,ko:K16153	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R00292,R02111	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT3,GT35	-	DUF3417,Phosphorylase
k59_1695607_1	1150621.SMUL_2928	9.59e-40	146.0	COG2986@1|root,COG2986@2|Bacteria,1MU6K@1224|Proteobacteria,42MST@68525|delta/epsilon subdivisions,2YNF3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Aromatic amino acid lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
k59_1695607_2	1094557.ME3_00876	3.02e-21	92.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,2TQZG@28211|Alphaproteobacteria,48T5P@772|Bartonellaceae	28211|Alphaproteobacteria	IQ	KR domain	fabG	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_747478_1	1537917.JU82_07085	6.05e-224	632.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2YMMU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_174313_1	1071679.BG57_12600	7.34e-95	296.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,2VH4P@28216|Betaproteobacteria,1K0GV@119060|Burkholderiaceae	28216|Betaproteobacteria	T	PFAM PhoH family protein	phoH	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
k59_1110616_1	159087.Daro_4163	3.02e-49	170.0	COG1032@1|root,COG1032@2|Bacteria,1Q5NG@1224|Proteobacteria,2VPEG@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Protein of unknown function (DUF4080)	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4080,Radical_SAM
k59_287693_1	159087.Daro_0655	1.73e-54	178.0	COG0491@1|root,COG0491@2|Bacteria,1MXKX@1224|Proteobacteria,2VIZ8@28216|Betaproteobacteria,2KVMB@206389|Rhodocyclales	206389|Rhodocyclales	S	Beta-lactamase	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
k59_287693_2	1304883.KI912532_gene259	5.95e-32	118.0	COG2267@1|root,COG2267@2|Bacteria,1MUG8@1224|Proteobacteria,2WHDA@28216|Betaproteobacteria,2KXUH@206389|Rhodocyclales	206389|Rhodocyclales	I	Alpha/beta hydrolase of unknown function (DUF915)	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_340431_1	1028800.RG540_CH13710	2.53e-131	391.0	COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1QT52@1224|Proteobacteria,2TVNI@28211|Alphaproteobacteria,4BIA7@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	Toprim-like	-	-	3.6.4.12	ko:K17680	-	-	-	-	ko00000,ko01000,ko03029	-	-	-	DnaB_C,Toprim_2
k59_340431_2	794903.OPIT5_08140	1.66e-79	243.0	COG0270@1|root,COG0270@2|Bacteria	2|Bacteria	L	DNA (cytosine-5-)-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_340431_3	160488.PP_2273	1.6e-16	80.1	COG0749@1|root,COG0749@2|Bacteria,1P27P@1224|Proteobacteria,1SJP1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	DNA polymerase family A	-	-	-	-	-	-	-	-	-	-	-	-	DNA_pol_A
k59_104799_1	709032.Sulku_1948	4.08e-133	389.0	COG2197@1|root,COG2197@2|Bacteria,1Q4EG@1224|Proteobacteria,42Z0G@68525|delta/epsilon subdivisions,2YRJG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_401825_1	1165841.SULAR_00060	1.13e-78	256.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2YMAI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k59_48353_1	709032.Sulku_0978	1.94e-66	213.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,42MBF@68525|delta/epsilon subdivisions,2YM9C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Glutamate-1-semialdehyde aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_1520590_1	1304883.KI912532_gene2928	1.59e-117	368.0	COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,2VIMP@28216|Betaproteobacteria,2KV97@206389|Rhodocyclales	206389|Rhodocyclales	NU	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_8
k59_747526_1	709032.Sulku_2281	4.68e-55	180.0	COG0598@1|root,COG0598@2|Bacteria,1MWMP@1224|Proteobacteria,42KZB@68525|delta/epsilon subdivisions,2YN63@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
k59_747526_2	709032.Sulku_2282	5.76e-53	174.0	COG0535@1|root,COG0535@2|Bacteria,1N2I6@1224|Proteobacteria,42P9K@68525|delta/epsilon subdivisions,2YNK6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
k59_819356_1	1304883.KI912532_gene2028	1.11e-70	224.0	28I8W@1|root,2Z8BP@2|Bacteria,1N0SC@1224|Proteobacteria,2VK0J@28216|Betaproteobacteria,2KVDQ@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF2863)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2863
k59_1520607_1	666685.R2APBS1_0158	4.74e-12	63.9	COG0607@1|root,32YCZ@2|Bacteria,1N6NN@1224|Proteobacteria,1SCRA@1236|Gammaproteobacteria,1X8IF@135614|Xanthomonadales	135614|Xanthomonadales	P	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
k59_1520607_2	1131812.JQMS01000001_gene3214	0.000527	43.9	COG0474@1|root,COG0474@2|Bacteria,4NERM@976|Bacteroidetes,1HY67@117743|Flavobacteriia,2NT0H@237|Flavobacterium	976|Bacteroidetes	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
k59_524903_1	709032.Sulku_0955	2.75e-102	303.0	COG0177@1|root,COG0177@2|Bacteria,1RAK3@1224|Proteobacteria,42M4V@68525|delta/epsilon subdivisions,2YNKT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	tigr02757	-	-	-	-	-	-	-	-	-	-	-	-	DUF2400
k59_1695720_1	749222.Nitsa_1949	3.01e-110	338.0	COG2956@1|root,COG2956@2|Bacteria,1PDTB@1224|Proteobacteria,42PNY@68525|delta/epsilon subdivisions,2YN3M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	ciaB	-	-	-	-	-	-	-	-	-	-	-	-
k59_287811_1	709032.Sulku_0468	3.82e-103	305.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,42MNA@68525|delta/epsilon subdivisions,2YMK1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	OU	signal peptide peptidase SppA, 36K type	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
k59_1402816_1	62928.azo3581	1.24e-125	375.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,2VHGF@28216|Betaproteobacteria,2KV01@206389|Rhodocyclales	206389|Rhodocyclales	GM	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
k59_524925_1	1249480.B649_00440	8.95e-117	338.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,42MRX@68525|delta/epsilon subdivisions,2YMC6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0566	DAP_epimerase
k59_1110765_1	94624.Bpet0908	7.57e-28	111.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,2VHBP@28216|Betaproteobacteria,3T2IE@506|Alcaligenaceae	28216|Betaproteobacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dusB	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
k59_1520662_1	665029.EAMY_2789	9.38e-59	197.0	COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,1RMYQ@1236|Gammaproteobacteria,3X4GD@551|Erwinia	1236|Gammaproteobacteria	J	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon	gluQ	GO:0000166,GO:0002097,GO:0003674,GO:0005488,GO:0005524,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363	-	ko:K01894	-	-	-	-	ko00000,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c
k59_1520662_2	1123514.KB905899_gene970	6.19e-56	179.0	COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,1S47H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
k59_1343045_2	387093.SUN_1257	9.14e-70	221.0	COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,42NEN@68525|delta/epsilon subdivisions,2YN4D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k59_1343046_1	670487.Ocepr_1221	2.89e-16	79.7	COG0210@1|root,COG0210@2|Bacteria,1WI0I@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	PFAM UvrD REP helicase	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DUF3553,UvrD-helicase,UvrD_C
k59_1343046_2	520999.PROVALCAL_01258	2.7e-36	125.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,1S5WR@1236|Gammaproteobacteria,3Z92W@586|Providencia	1236|Gammaproteobacteria	O	Belongs to the thioredoxin family	trxA	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	iECW_1372.ECW_m4079,iECs_1301.ECs4714,iEKO11_1354.EKO11_4576,iG2583_1286.G2583_4574,iSBO_1134.SBO_3791,iSDY_1059.SDY_3968,iSF_1195.SF3854,iSSON_1240.SSON_3952,iS_1188.S3905,iWFL_1372.ECW_m4079,iZ_1308.Z5291	Thioredoxin
k59_174551_1	1442598.JABW01000011_gene332	4.68e-19	84.3	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,42M0Q@68525|delta/epsilon subdivisions,2YMXU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k59_174551_2	1249480.B649_10230	1.28e-91	278.0	COG3303@1|root,COG3303@2|Bacteria,1QUJG@1224|Proteobacteria,42RGW@68525|delta/epsilon subdivisions,2YMPH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
k59_462610_1	709032.Sulku_1404	1.35e-40	139.0	COG0569@1|root,COG0569@2|Bacteria,1R7KM@1224|Proteobacteria,42PJH@68525|delta/epsilon subdivisions,2YP5Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	uptake protein	ktrA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
k59_462610_2	709032.Sulku_1405	9.34e-34	129.0	COG2199@1|root,COG3706@2|Bacteria,1NFQH@1224|Proteobacteria,42S2B@68525|delta/epsilon subdivisions,2YPCT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PFAM Type IV pilus assembly PilZ	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_340659_1	1249480.B649_08150	2.65e-190	535.0	COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,43DRR@68525|delta/epsilon subdivisions,2YMSV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	o-acetylhomoserine	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
k59_1760607_1	90814.KL370891_gene80	2.59e-14	70.5	COG1826@1|root,COG1826@2|Bacteria,1N73F@1224|Proteobacteria,1SD9K@1236|Gammaproteobacteria,46175@72273|Thiotrichales	72273|Thiotrichales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation	tatB	-	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
k59_1760607_2	1123517.JOMR01000001_gene3	1.37e-15	72.8	COG1826@1|root,COG1826@2|Bacteria,1N6S4@1224|Proteobacteria,1SCC7@1236|Gammaproteobacteria,461D2@72273|Thiotrichales	72273|Thiotrichales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
k59_1760607_3	717773.Thicy_1541	1.37e-50	161.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,1S3QE@1236|Gammaproteobacteria,4610M@72273|Thiotrichales	72273|Thiotrichales	FG	Histidine triad (HIT) protein	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
k59_344889_1	1537917.JU82_06765	7.73e-84	254.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,42NBS@68525|delta/epsilon subdivisions,2YMPP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	riboflavin biosynthesis protein	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
k59_344889_2	709032.Sulku_0462	8.64e-47	153.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,42THF@68525|delta/epsilon subdivisions,2YPXJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
k59_466798_1	709032.Sulku_0377	2.41e-95	293.0	COG0778@1|root,COG0778@2|Bacteria,1Q0G9@1224|Proteobacteria,42QDE@68525|delta/epsilon subdivisions,2YMPN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_1760624_1	1282876.BAOK01000002_gene221	4.72e-94	295.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria,4BTBE@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	CG	PQQ enzyme repeat	-	-	1.1.9.1	ko:K17760	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
k59_1407479_1	1537917.JU82_10610	1.84e-54	184.0	COG4773@1|root,COG4773@2|Bacteria,1PP2I@1224|Proteobacteria,42WFP@68525|delta/epsilon subdivisions,2YQM1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Receptor	-	-	-	-	-	-	-	-	-	-	-	-	OprD
k59_51259_1	159087.Daro_0179	6.9e-114	337.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,2VH51@28216|Betaproteobacteria,2KVTM@206389|Rhodocyclales	206389|Rhodocyclales	O	Collagenase and related proteases	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
k59_1230215_1	1249480.B649_00595	9.24e-123	374.0	COG0715@1|root,COG0834@1|root,COG4191@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PNA@68525|delta/epsilon subdivisions,2YTBI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EPT	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,NMT1,SBP_bac_3
k59_1407559_2	1144325.PMI22_04840	1.3e-45	157.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,1RPCE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Catalyzes the transfer of 4-deoxy-4-formamido-L- arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides	-	-	2.4.2.53	ko:K10012	ko00520,ko01503,map00520,map01503	M00721,M00761	R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.8	GT2	-	Glycos_transf_2
k59_344986_1	583345.Mmol_0038	2.13e-20	86.7	COG5424@1|root,COG5424@2|Bacteria,1QVK0@1224|Proteobacteria,2VMEZ@28216|Betaproteobacteria,2KKMF@206350|Nitrosomonadales	206350|Nitrosomonadales	H	Iron-containing redox enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Haem_oxygenas_2
k59_344986_2	96561.Dole_0314	5.58e-05	48.9	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,42N2G@68525|delta/epsilon subdivisions,2WIXB@28221|Deltaproteobacteria,2MHVC@213118|Desulfobacterales	28221|Deltaproteobacteria	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
k59_1346960_1	709032.Sulku_1858	1.35e-16	76.3	COG2928@1|root,COG2928@2|Bacteria,1PKH9@1224|Proteobacteria,42XVN@68525|delta/epsilon subdivisions,2YQSF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
k59_1346960_2	1249480.B649_08885	1.14e-70	223.0	COG0265@1|root,COG0265@2|Bacteria,1NVFS@1224|Proteobacteria,42Z4E@68525|delta/epsilon subdivisions,2YRIR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Peptidase s1	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
k59_1114848_1	1537917.JU82_02645	7.21e-131	377.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,42M0Q@68525|delta/epsilon subdivisions,2YMXU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k59_1114853_1	387093.SUN_1316	1.47e-92	295.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,42M4I@68525|delta/epsilon subdivisions,2YMFT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_1230311_1	1249480.B649_10570	9.26e-85	259.0	COG4968@1|root,COG4968@2|Bacteria,1R1K8@1224|Proteobacteria,43DAN@68525|delta/epsilon subdivisions,2YTHS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
k59_345065_1	395494.Galf_2895	7.63e-33	118.0	COG2823@1|root,COG2823@2|Bacteria,1MUZ2@1224|Proteobacteria,2VQIS@28216|Betaproteobacteria,44VX2@713636|Nitrosomonadales	28216|Betaproteobacteria	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
k59_345065_2	395494.Galf_2896	3.06e-48	157.0	COG0615@1|root,COG0615@2|Bacteria,1REW3@1224|Proteobacteria,2VR6S@28216|Betaproteobacteria,44VQT@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	aut	-	2.7.7.70	ko:K21345	ko00540,ko01100,map00540,map01100	M00064	R05644	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
k59_405999_1	159087.Daro_0752	3.12e-16	77.8	COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,2VIV1@28216|Betaproteobacteria,2KVFK@206389|Rhodocyclales	206389|Rhodocyclales	N	Flagellar hook protein FlgE	flgE	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bb_rod,Flg_bbr_C
k59_405999_2	1500894.JQNN01000001_gene2586	9.92e-41	145.0	COG1843@1|root,COG1843@2|Bacteria,1MXCG@1224|Proteobacteria,2VSF6@28216|Betaproteobacteria,474BB@75682|Oxalobacteraceae	28216|Betaproteobacteria	N	Required for flagellar hook formation. May act as a scaffolding protein	flgD	-	-	ko:K02389	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FLgD_tudor,FlgD,FlgD_ig
k59_1407664_1	709032.Sulku_1882	1.67e-59	192.0	COG1090@1|root,COG1090@2|Bacteria,1MUB4@1224|Proteobacteria,42QUU@68525|delta/epsilon subdivisions,2YNXM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Epimerase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
k59_1760796_1	1121861.KB899915_gene1863	1.09e-56	206.0	28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,2TVGJ@28211|Alphaproteobacteria,2JPR0@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1407683_1	543913.D521_0896	5.3e-60	204.0	COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,2VHBQ@28216|Betaproteobacteria,1KQ87@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_467004_2	1163408.UU9_11658	7.83e-31	121.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,1RSHX@1236|Gammaproteobacteria,1X3T3@135614|Xanthomonadales	135614|Xanthomonadales	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
k59_1407689_1	159087.Daro_2938	3.94e-108	332.0	28MTI@1|root,2ZB1Q@2|Bacteria,1R894@1224|Proteobacteria,2VMZB@28216|Betaproteobacteria,2KVD1@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_345146_1	709032.Sulku_0948	2.71e-94	291.0	COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,42N0P@68525|delta/epsilon subdivisions,2YN14@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	UPF0313 protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,Radical_SAM_N
k59_345146_2	1165841.SULAR_03108	4.49e-45	153.0	COG0561@1|root,COG0561@2|Bacteria,1Q5G6@1224|Proteobacteria,42R7D@68525|delta/epsilon subdivisions,2YP2E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	of the HAD superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
k59_1114963_1	1304883.KI912532_gene291	2.24e-05	45.8	COG0784@1|root,COG0784@2|Bacteria,1QWFW@1224|Proteobacteria,2VPCN@28216|Betaproteobacteria,2KVZ3@206389|Rhodocyclales	206389|Rhodocyclales	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
k59_1114963_2	178901.AmDm5_3084	9.64e-45	149.0	COG0655@1|root,COG0655@2|Bacteria,1MW7N@1224|Proteobacteria,2TR4Z@28211|Alphaproteobacteria,2JSDK@204441|Rhodospirillales	204441|Rhodospirillales	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
k59_1114979_2	159087.Daro_0875	4.13e-89	264.0	COG1286@1|root,COG1286@2|Bacteria,1NF4G@1224|Proteobacteria,2VUM6@28216|Betaproteobacteria,2KWGU@206389|Rhodocyclales	206389|Rhodocyclales	S	colicin v production	cvpA	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
k59_1760893_2	62928.azo0063	2.34e-11	62.8	COG2361@1|root,COG2361@2|Bacteria	2|Bacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
k59_1407804_2	383372.Rcas_3195	8.78e-36	137.0	COG0457@1|root,COG1352@1|root,COG0457@2|Bacteria,COG1352@2|Bacteria,2G79T@200795|Chloroflexi,3765U@32061|Chloroflexia	32061|Chloroflexia	NT	PFAM MCP methyltransferase CheR-type	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,TPR_16
k59_1230480_1	159087.Daro_3571	5.65e-93	289.0	COG0517@1|root,COG2199@1|root,COG2200@1|root,COG0517@2|Bacteria,COG2199@2|Bacteria,COG2200@2|Bacteria,1MVJY@1224|Proteobacteria,2VI53@28216|Betaproteobacteria,2KUU5@206389|Rhodocyclales	206389|Rhodocyclales	T	EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_406129_1	159087.Daro_1063	1.63e-65	212.0	COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,2VGZY@28216|Betaproteobacteria,2KVU5@206389|Rhodocyclales	206389|Rhodocyclales	K	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
k59_291227_1	709032.Sulku_0327	3.66e-78	250.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,42MB1@68525|delta/epsilon subdivisions,2YMVC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
k59_108793_1	1144319.PMI16_01877	2.5e-29	120.0	COG4796@1|root,COG4796@2|Bacteria,1QUY7@1224|Proteobacteria,2VJ8Z@28216|Betaproteobacteria,472RY@75682|Oxalobacteraceae	28216|Betaproteobacteria	U	Secretin and TonB N terminus short domain	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Cohesin,STN,Secretin,Secretin_N
k59_1230509_1	1165841.SULAR_08859	6.31e-22	93.2	COG2046@1|root,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,42NAI@68525|delta/epsilon subdivisions,2YME3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	sulfate adenylyltransferase	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
k59_1480074_1	709032.Sulku_1113	5.43e-55	178.0	COG1338@1|root,COG1338@2|Bacteria,1MVBU@1224|Proteobacteria,42NDZ@68525|delta/epsilon subdivisions,2YMJ1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Plays a role in the flagellum-specific transport system	fliP	-	-	ko:K02419	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliP
k59_1480074_2	929558.SMGD1_2807	6.58e-110	324.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,42Q7D@68525|delta/epsilon subdivisions,2YMSU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Membrane MotB of proton-channel complex MotA/MotB	motS	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
k59_1833833_1	709032.Sulku_0675	1e-64	214.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,42NGS@68525|delta/epsilon subdivisions,2YMZZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Ribonuclease	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB
k59_1833833_2	709032.Sulku_0674	1.01e-37	134.0	COG1466@1|root,COG1466@2|Bacteria,1RHE9@1224|Proteobacteria,42RI9@68525|delta/epsilon subdivisions,2YP40@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA polymerase III	-	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
k59_1361407_1	1291050.JAGE01000001_gene2920	1.3e-44	158.0	COG4695@1|root,COG4695@2|Bacteria,1TP8B@1239|Firmicutes,2497C@186801|Clostridia	186801|Clostridia	OU	Phage portal protein, HK97 family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_portal
k59_599458_1	29581.BW37_01335	3.55e-112	337.0	COG1785@1|root,COG1785@2|Bacteria,1MXI2@1224|Proteobacteria,2VKXB@28216|Betaproteobacteria,473VM@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	Alkaline phosphatase homologues	phoA1	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
k59_130637_1	1537917.JU82_11390	4.03e-132	378.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,42P96@68525|delta/epsilon subdivisions,2YTJM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	abc transporter atp-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_130637_2	1537917.JU82_11395	5.12e-96	290.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,42MAR@68525|delta/epsilon subdivisions,2YMC4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	ABC transporter	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_952439_1	1249480.B649_01680	2.11e-179	509.0	COG1776@1|root,COG1776@2|Bacteria,1RICK@1224|Proteobacteria,42NMU@68525|delta/epsilon subdivisions,2YMV4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Chemotaxis phosphatase CheX	-	-	-	-	-	-	-	-	-	-	-	-	CheX
k59_1833864_1	1249480.B649_04795	1.38e-182	536.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2YMQV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_246842_1	666681.M301_2003	7.99e-59	189.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,2VJC3@28216|Betaproteobacteria,2KKZJ@206350|Nitrosomonadales	206350|Nitrosomonadales	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
k59_1422191_1	1163617.SCD_n02872	8.37e-69	221.0	COG0859@1|root,COG0859@2|Bacteria,1NEWM@1224|Proteobacteria,2VQ5K@28216|Betaproteobacteria	28216|Betaproteobacteria	M	family 9	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
k59_1422191_2	46429.BV95_01426	3.66e-10	62.0	COG0500@1|root,COG0500@2|Bacteria,1QV5S@1224|Proteobacteria,2TWAD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k59_1128965_1	717773.Thicy_1171	6.9e-58	201.0	COG0116@1|root,COG1092@1|root,COG0116@2|Bacteria,COG1092@2|Bacteria,1MUQM@1224|Proteobacteria,1RNMH@1236|Gammaproteobacteria,46089@72273|Thiotrichales	72273|Thiotrichales	J	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA	rlmL	-	2.1.1.173,2.1.1.264	ko:K12297	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,THUMP,UPF0020
k59_1480109_1	1123517.JOMR01000001_gene1044	1.01e-53	192.0	COG2972@1|root,COG5002@1|root,COG2972@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg,dCache_1
k59_1185848_1	342113.DM82_6011	1.36e-111	336.0	COG3039@1|root,COG3039@2|Bacteria,1MVTU@1224|Proteobacteria,2VK8B@28216|Betaproteobacteria,1K1CT@119060|Burkholderiaceae	28216|Betaproteobacteria	L	COG Transposase and inactivated derivatives, IS5 family	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF772
k59_1246956_2	1537917.JU82_09130	2.71e-81	246.0	28WAS@1|root,2ZIB8@2|Bacteria,1NBB7@1224|Proteobacteria,42P2G@68525|delta/epsilon subdivisions,2YNQ5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1246956_3	1537917.JU82_09135	4.21e-147	422.0	COG0754@1|root,COG0754@2|Bacteria,1MW6V@1224|Proteobacteria,42N3V@68525|delta/epsilon subdivisions,2YMBJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Glutathionylspermidine synthase	gss	-	-	-	-	-	-	-	-	-	-	-	GSP_synth
k59_422404_1	857087.Metme_0111	5.12e-47	172.0	COG2202@1|root,COG3447@1|root,COG3614@1|root,COG5001@1|root,COG2202@2|Bacteria,COG3447@2|Bacteria,COG3614@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CZB,EAL,GAF_2,GGDEF,NMT1,PAS_4,PAS_9,Protoglobin,SBP_bac_3
k59_1833879_1	948106.AWZT01000003_gene5884	1.2e-47	166.0	COG4638@1|root,COG4638@2|Bacteria,1R5C3@1224|Proteobacteria,2VWZ8@28216|Betaproteobacteria,1K305@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Ring hydroxylating alpha subunit (catalytic domain)	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Ring_hydroxyl_A
k59_834781_1	709032.Sulku_1406	5.5e-105	315.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,42NHA@68525|delta/epsilon subdivisions,2YMYU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX1	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
k59_1540213_2	159087.Daro_0324	1.24e-71	215.0	COG0091@1|root,COG0091@2|Bacteria,1RH0W@1224|Proteobacteria,2VSE6@28216|Betaproteobacteria,2KWKB@206389|Rhodocyclales	206389|Rhodocyclales	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
k59_1540213_3	159087.Daro_0325	3.02e-69	214.0	COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,2VHQN@28216|Betaproteobacteria,2KVIT@206389|Rhodocyclales	206389|Rhodocyclales	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
k59_303604_1	1249480.B649_08770	1.64e-75	226.0	COG1699@1|root,COG1699@2|Bacteria,1N347@1224|Proteobacteria,42RNU@68525|delta/epsilon subdivisions,2YPKW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum	fliW	-	-	ko:K13626	-	-	-	-	ko00000,ko02035	-	-	-	FliW
k59_303604_2	709032.Sulku_0712	1.94e-67	224.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,42MPZ@68525|delta/epsilon subdivisions,2YM8C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k59_1361461_1	1249480.B649_00245	7.2e-81	258.0	COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,42NGP@68525|delta/epsilon subdivisions,2YN81@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Flagellar hook protein flgE	flgE	GO:0005575,GO:0005623,GO:0009288,GO:0009425,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flagellin_IN,Flg_bb_rod,Flg_bbr_C
k59_773822_1	1537917.JU82_05270	2.6e-68	209.0	COG0607@1|root,COG0607@2|Bacteria,1R70B@1224|Proteobacteria,42UX5@68525|delta/epsilon subdivisions,2YPT0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Rhodanese-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_834806_1	1249480.B649_05665	5.91e-132	377.0	COG3852@1|root,COG3852@2|Bacteria,1QAGK@1224|Proteobacteria,42RSW@68525|delta/epsilon subdivisions,2YPDC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1540225_1	225849.swp_0570	1.14e-18	94.7	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,2QETN@267890|Shewanellaceae	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
k59_542741_1	1537917.JU82_00860	4.02e-84	261.0	COG1807@1|root,COG1807@2|Bacteria,1Q901@1224|Proteobacteria,42MGX@68525|delta/epsilon subdivisions,2YNER@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
k59_68963_1	909663.KI867151_gene3000	8.53e-69	220.0	COG1215@1|root,COG1215@2|Bacteria,1MWH9@1224|Proteobacteria,42PX0@68525|delta/epsilon subdivisions,2WJUG@28221|Deltaproteobacteria,2MQYT@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	-	-	2.4.1.266	ko:K13693	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	-
k59_1772900_1	709032.Sulku_0392	3.62e-36	122.0	COG2501@1|root,COG2501@2|Bacteria,1PFA5@1224|Proteobacteria,42XJ3@68525|delta/epsilon subdivisions,2YS84@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	S4 domain	-	-	-	ko:K14761	-	-	-	-	ko00000,ko03009	-	-	-	S4_2
k59_363133_1	1163617.SCD_n02290	9.43e-32	130.0	COG3437@1|root,COG3829@1|root,COG4191@1|root,COG5001@1|root,COG3437@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_3,PAS_9,Response_reg
k59_303639_2	709032.Sulku_0471	5.53e-80	243.0	COG1776@1|root,COG1776@2|Bacteria,1N49I@1224|Proteobacteria,42UKN@68525|delta/epsilon subdivisions,2YQBN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	COGs COG1776 Chemotaxis protein CheC inhibitor of MCP methylation	-	-	-	ko:K03410	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheC,CheX
k59_1247024_1	709032.Sulku_0578	5.81e-76	241.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,42MS8@68525|delta/epsilon subdivisions,2YMUQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
k59_1247024_2	709032.Sulku_0579	5.44e-20	88.6	COG1847@1|root,COG1847@2|Bacteria,1RB1P@1224|Proteobacteria,42QYV@68525|delta/epsilon subdivisions,2YNW5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Jag_N	-	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N
k59_542773_1	1537917.JU82_06590	4.28e-127	370.0	COG0330@1|root,COG0330@2|Bacteria,1N5JY@1224|Proteobacteria,42MNX@68525|delta/epsilon subdivisions,2YME9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	COG0330 Membrane protease subunits stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_542774_1	1537917.JU82_10045	4.28e-40	145.0	2DCNX@1|root,2ZESX@2|Bacteria,1QUV9@1224|Proteobacteria,43CMN@68525|delta/epsilon subdivisions,2YTEI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_542774_2	1249480.B649_00295	1.63e-19	80.9	2BTPW@1|root,32NWY@2|Bacteria,1Q3ZS@1224|Proteobacteria,42Y1G@68525|delta/epsilon subdivisions,2YQR3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Uncharacterized conserved protein (DUF2249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2249
k59_834852_2	1249480.B649_00250	5.15e-75	238.0	COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,42MPN@68525|delta/epsilon subdivisions,2YMHV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Flagellar basal body protein	flgE	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bb_rod,Flg_bbr_C
k59_659950_1	709032.Sulku_1376	1.26e-30	119.0	COG0515@1|root,COG0631@1|root,COG0515@2|Bacteria,COG0631@2|Bacteria,1MV1P@1224|Proteobacteria,42MVV@68525|delta/epsilon subdivisions,2YNMJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KLT	COG0631 Serine threonine protein phosphatase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PP2C_2,Pkinase
k59_599561_1	1537917.JU82_07640	1.03e-218	610.0	COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,42M78@68525|delta/epsilon subdivisions,2YMR1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
k59_599561_2	1249480.B649_03870	7.82e-14	68.6	COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,42MAM@68525|delta/epsilon subdivisions,2YT9B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	ABC transporter	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
k59_1540282_1	1537917.JU82_03935	5.87e-21	87.0	2BR0I@1|root,32JXY@2|Bacteria,1Q8HJ@1224|Proteobacteria,433K7@68525|delta/epsilon subdivisions,2YSTW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1540282_2	1537915.JU57_04875	1.55e-06	53.1	2BR0I@1|root,32JXY@2|Bacteria,1Q8HJ@1224|Proteobacteria,433K7@68525|delta/epsilon subdivisions,2YSTW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1302362_1	159087.Daro_3895	4.72e-117	378.0	COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VJSZ@28216|Betaproteobacteria,2KUBP@206389|Rhodocyclales	206389|Rhodocyclales	KNT	COG0643 Chemotaxis protein histidine kinase and related kinases	pilL	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,HATPase_c,Hpt,Response_reg
k59_1247071_1	1165841.SULAR_06043	1.7e-84	268.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,42MP3@68525|delta/epsilon subdivisions,2YMP3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
k59_1596991_1	1165841.SULAR_07905	4.28e-72	217.0	COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,42R43@68525|delta/epsilon subdivisions,2YP73@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
k59_1596991_2	387093.SUN_2346	9.81e-45	149.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,42M5X@68525|delta/epsilon subdivisions,2YMCY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
k59_303679_1	1249480.B649_09460	4.39e-25	103.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,42KZI@68525|delta/epsilon subdivisions,2YR60@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Domain of unknown function (DUF3458_C) ARM repeats	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,Peptidase_M1
k59_303679_2	749222.Nitsa_0492	5.59e-21	89.0	COG0745@1|root,COG0745@2|Bacteria,1QZNH@1224|Proteobacteria,42SJZ@68525|delta/epsilon subdivisions,2YPIE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_1247078_1	159087.Daro_2995	2.42e-156	456.0	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VI6T@28216|Betaproteobacteria,2KUUR@206389|Rhodocyclales	206389|Rhodocyclales	T	Signal transduction histidine kinase	dctS	-	2.7.13.3	ko:K11711	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS
k59_483209_1	1537917.JU82_00485	1.94e-95	283.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,42QAC@68525|delta/epsilon subdivisions,2YNGY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
k59_1422337_1	1537917.JU82_05220	1.95e-31	110.0	COG2501@1|root,COG2501@2|Bacteria,1PFA5@1224|Proteobacteria,42XJ3@68525|delta/epsilon subdivisions,2YS84@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	S4 domain	-	-	-	ko:K14761	-	-	-	-	ko00000,ko03009	-	-	-	S4_2
k59_1715499_1	317025.Tcr_0969	1.96e-52	172.0	COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,1RMD0@1236|Gammaproteobacteria,460H6@72273|Thiotrichales	72273|Thiotrichales	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07664	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_1715499_2	870187.Thini_1116	7.38e-20	89.0	COG5002@1|root,COG5002@2|Bacteria,1QU7C@1224|Proteobacteria,1T1PS@1236|Gammaproteobacteria,45ZP2@72273|Thiotrichales	72273|Thiotrichales	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
k59_248319_1	709032.Sulku_2313	3.51e-141	407.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,42MD6@68525|delta/epsilon subdivisions,2YMXT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petB	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
k59_1187092_1	709032.Sulku_0716	3e-25	103.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2YMIX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	ctsE	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
k59_1187092_2	1537917.JU82_08685	1.51e-69	221.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42NES@68525|delta/epsilon subdivisions,2YMT3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Type II secretion system	ctsF	-	-	ko:K02455,ko:K12278	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
k59_1423957_1	1165841.SULAR_02163	1.07e-52	167.0	COG1942@1|root,COG1942@2|Bacteria,1RDK8@1224|Proteobacteria,430P9@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Tautomerase enzyme	Z012_06190	-	-	-	-	-	-	-	-	-	-	-	Tautomerase_2
k59_1423957_2	1165841.SULAR_02168	1.48e-119	344.0	COG0500@1|root,COG2226@2|Bacteria,1RF5Y@1224|Proteobacteria,42U9R@68525|delta/epsilon subdivisions,2YRQQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_132290_1	588581.Cpap_0078	5.18e-76	255.0	COG3321@1|root,COG4221@1|root,COG3321@2|Bacteria,COG4221@2|Bacteria,1VU8Z@1239|Firmicutes	2|Bacteria	Q	synthase	pksR	-	-	ko:K13614	-	-	-	-	ko00000,ko01004,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,Thioesterase,ketoacyl-synt
k59_423766_1	1249480.B649_08130	2.54e-80	258.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42UBD@68525|delta/epsilon subdivisions,2YRGP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	7TM diverse intracellular signalling	-	-	-	ko:K20971	ko02025,map02025	-	-	-	ko00000,ko00001,ko01001,ko02022	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c
k59_305039_1	709032.Sulku_1463	1.2e-107	317.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,42KZJ@68525|delta/epsilon subdivisions,2YMR0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
k59_714691_1	1249480.B649_11090	1.84e-135	406.0	COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,1QUIU@1224|Proteobacteria,42M7I@68525|delta/epsilon subdivisions,2YMX0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG3893 inactivated superfamily I helicase	addB	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
k59_1481607_1	1496688.ER33_08250	1.35e-31	123.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1149@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1149@2|Bacteria,1G2E2@1117|Cyanobacteria,22SJE@167375|Cyanobium	1117|Cyanobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016491,GO:0050896,GO:0055114	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iJN678.nifJ	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
k59_1481607_2	749222.Nitsa_2114	1.82e-31	113.0	COG0011@1|root,COG0011@2|Bacteria,1N0UT@1224|Proteobacteria,43B8R@68525|delta/epsilon subdivisions,2YT6Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Thiamine-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
k59_953939_1	1304883.KI912532_gene544	8.72e-120	371.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,2VH05@28216|Betaproteobacteria,2KVJX@206389|Rhodocyclales	206389|Rhodocyclales	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
k59_1303472_1	1537917.JU82_08040	2.26e-197	568.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2YMW4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_1303472_2	709032.Sulku_0431	1.21e-08	55.1	COG0287@1|root,COG0287@2|Bacteria,1QTZA@1224|Proteobacteria,42MH0@68525|delta/epsilon subdivisions,2YMHS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
k59_1013858_1	159087.Daro_3078	4.78e-08	54.7	2E3UK@1|root,32YRY@2|Bacteria,1N74J@1224|Proteobacteria,2VVQ2@28216|Betaproteobacteria,2KX7S@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF3106)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3106
k59_1013858_2	1304883.KI912532_gene3084	3.18e-29	107.0	2E95F@1|root,333E6@2|Bacteria,1N8N7@1224|Proteobacteria,2VWBC@28216|Betaproteobacteria,2KXMZ@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF3619)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3619
k59_1248733_1	159087.Daro_2016	3.85e-139	399.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,2VJF7@28216|Betaproteobacteria,2KV8M@206389|Rhodocyclales	206389|Rhodocyclales	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
k59_1598183_1	511062.GU3_13345	4.88e-15	81.6	COG3144@1|root,COG3144@2|Bacteria,1PC67@1224|Proteobacteria,1SX0J@1236|Gammaproteobacteria,1Y657@135624|Aeromonadales	135624|Aeromonadales	N	Flagellar hook-length control protein	-	-	-	ko:K02414	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_hook
k59_1130621_1	1249480.B649_09595	2.19e-31	114.0	COG0680@1|root,COG0680@2|Bacteria,1RE1C@1224|Proteobacteria,42REH@68525|delta/epsilon subdivisions,2YP5U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	hydrogenase maturation protease	hydD	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
k59_1130621_2	1249480.B649_09600	9.2e-41	150.0	COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,42M3G@68525|delta/epsilon subdivisions,2YM8M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
k59_1835617_1	305700.B447_18558	5.49e-64	220.0	COG4191@1|root,COG5001@1|root,COG4191@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KUCK@206389|Rhodocyclales	206389|Rhodocyclales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CZB,EAL,GAF,GGDEF,PAS,PAS_3,PAS_4,PAS_9
k59_661676_1	617140.AJZE01000046_gene588	1.82e-29	124.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,1RPSJ@1236|Gammaproteobacteria,1XTQS@135623|Vibrionales	135623|Vibrionales	T	containing cAMP-binding and CBS domains	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
k59_601004_1	159087.Daro_1048	4.2e-89	274.0	COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,2VJ1F@28216|Betaproteobacteria,2KVK4@206389|Rhodocyclales	206389|Rhodocyclales	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
k59_953979_1	1249480.B649_00725	1.14e-78	240.0	COG1639@1|root,COG1639@2|Bacteria,1RAH3@1224|Proteobacteria,42PRF@68525|delta/epsilon subdivisions,2YMRX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Signal transduction protein	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_893924_1	395494.Galf_1460	3.69e-31	124.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2VM3A@28216|Betaproteobacteria,44WJ7@713636|Nitrosomonadales	28216|Betaproteobacteria	S	SMART Sel1 domain protein repeat-containing protein	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	SPOR,Sel1
k59_1541994_1	580332.Slit_2900	6.85e-87	265.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2VHA9@28216|Betaproteobacteria,44WGE@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	1.17.1.1	ko:K12452	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	DegT_DnrJ_EryC1
k59_1541994_2	1165096.ARWF01000001_gene487	2.6e-05	45.1	COG1208@1|root,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,2VIQG@28216|Betaproteobacteria,2KNI8@206350|Nitrosomonadales	206350|Nitrosomonadales	JM	Nucleotidyl transferase	-	-	2.7.7.71	ko:K15669	ko00540,map00540	-	R09772	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
k59_661695_1	1249480.B649_03285	3.8e-131	381.0	COG2199@1|root,COG3706@2|Bacteria,1NC00@1224|Proteobacteria,43DI1@68525|delta/epsilon subdivisions,2YTIQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	diguanylate cyclase	-	-	2.7.7.65	ko:K13590	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF
k59_661695_2	1537917.JU82_00885	6.22e-28	110.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,42MN5@68525|delta/epsilon subdivisions,2YN0Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	DUF294,GlnD_UR_UTase,HD,NTP_transf_2
k59_601028_1	387093.SUN_1138	3.1e-10	59.7	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,42NHA@68525|delta/epsilon subdivisions,2YMYU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX1	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
k59_601028_2	1165841.SULAR_04262	5.36e-42	139.0	COG0762@1|root,COG0762@2|Bacteria,1QDB9@1224|Proteobacteria,42VCU@68525|delta/epsilon subdivisions,2YQ8B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
k59_601028_3	749222.Nitsa_1317	1.13e-12	69.7	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,42N7A@68525|delta/epsilon subdivisions,2YMRE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	lytic murein transglycosylase	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
k59_484749_1	1249480.B649_02400	3.39e-97	288.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,42P56@68525|delta/epsilon subdivisions,2YNV5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
k59_484749_2	709032.Sulku_0480	3.2e-144	414.0	COG1776@1|root,COG1886@1|root,COG1776@2|Bacteria,COG1886@2|Bacteria,1NF4E@1224|Proteobacteria,42R4G@68525|delta/epsilon subdivisions,2YN6N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar motor switch protein	fliY	-	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FliMN_C
k59_1187183_1	1537917.JU82_03345	1.77e-29	105.0	2AN4M@1|root,31D2D@2|Bacteria,1QA3X@1224|Proteobacteria,433I5@68525|delta/epsilon subdivisions,2YSM0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_423850_1	582744.Msip34_2443	9.38e-115	355.0	COG4206@1|root,COG4206@2|Bacteria,1N71E@1224|Proteobacteria,2VJZ9@28216|Betaproteobacteria,2KKW2@206350|Nitrosomonadales	206350|Nitrosomonadales	H	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_484768_1	387093.SUN_0963	1.11e-25	112.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42NFY@68525|delta/epsilon subdivisions,2YREZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
k59_203102_1	1304883.KI912532_gene822	2.51e-132	388.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,2VHH0@28216|Betaproteobacteria,2KUSQ@206389|Rhodocyclales	206389|Rhodocyclales	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
k59_203102_2	305700.B447_02331	1.41e-10	55.8	COG0230@1|root,COG0230@2|Bacteria,1NGGS@1224|Proteobacteria,2VXTS@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
k59_1852425_1	388413.ALPR1_04283	6.24e-11	67.8	COG1629@1|root,COG4771@2|Bacteria,4NEIG@976|Bacteroidetes,47JGS@768503|Cytophagia	976|Bacteroidetes	P	TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
k59_561781_1	929558.SMGD1_1870	1.61e-06	55.5	COG2199@1|root,COG2200@1|root,COG4753@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,COG3706@2|Bacteria,COG4753@2|Bacteria,1R7HC@1224|Proteobacteria,42RY7@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,NMT1,PAS_3,PAS_9,Response_reg,SBP_bac_3
k59_791109_1	159087.Daro_3740	6.08e-116	339.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,2VI0Q@28216|Betaproteobacteria,2KV5I@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
k59_906975_1	563040.Saut_1535	3.23e-08	54.3	2AJNF@1|root,31A9U@2|Bacteria,1Q56P@1224|Proteobacteria,430NW@68525|delta/epsilon subdivisions,2YS38@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_906975_2	1537917.JU82_03200	2.11e-98	291.0	COG2733@1|root,COG2733@2|Bacteria,1R4JT@1224|Proteobacteria,42RK1@68525|delta/epsilon subdivisions,2YPBZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1314579_1	1132855.KB913035_gene1867	1.46e-168	478.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,2VIGA@28216|Betaproteobacteria,2KKZY@206350|Nitrosomonadales	206350|Nitrosomonadales	J	PFAM tRNA synthetase class II (G H P and S)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
k59_1729211_1	1249480.B649_10855	3.22e-35	128.0	COG1426@1|root,COG1426@2|Bacteria,1Q33C@1224|Proteobacteria,42WQB@68525|delta/epsilon subdivisions,2YQFX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1729211_3	709032.Sulku_2299	3.77e-94	284.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,42MEF@68525|delta/epsilon subdivisions,2YMMY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Aminotransferase	-	-	-	ko:K14261	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_1787405_1	1537917.JU82_02025	4.29e-18	89.0	COG0642@1|root,COG2205@2|Bacteria,1Q179@1224|Proteobacteria,4313A@68525|delta/epsilon subdivisions,2YS9S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07645	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	-
k59_1265826_1	159087.Daro_3031	1.51e-112	334.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,2VJ7Z@28216|Betaproteobacteria,2KUUD@206389|Rhodocyclales	206389|Rhodocyclales	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
k59_1265826_2	1100721.ALKO01000021_gene643	1.72e-18	82.8	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,2VIVG@28216|Betaproteobacteria,4AB2W@80864|Comamonadaceae	28216|Betaproteobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k59_261493_1	387093.SUN_0007	3.53e-118	347.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,42M5V@68525|delta/epsilon subdivisions,2YM81@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Cysteine desulfurase	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
k59_1787421_2	1537917.JU82_03085	7.88e-136	388.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,42R1M@68525|delta/epsilon subdivisions,2YNZ3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	fumarate reductase, iron-sulfur protein	-	-	1.3.5.4	ko:K00245	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
k59_1787421_4	709032.Sulku_0072	1.76e-143	418.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,42M81@68525|delta/epsilon subdivisions,2YMTF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_791180_1	709032.Sulku_1990	7.38e-93	283.0	COG0642@1|root,COG0642@2|Bacteria,1QUJK@1224|Proteobacteria,42PPA@68525|delta/epsilon subdivisions,2YMW6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
k59_1494292_1	1249480.B649_00695	2.49e-30	112.0	COG1670@1|root,COG1670@2|Bacteria,1NIVC@1224|Proteobacteria,42U80@68525|delta/epsilon subdivisions,2YPSY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Pseudaminic acid biosynthesis N-acetyl transferase	pseH	-	2.3.1.202	ko:K15896	ko00520,map00520	-	R09842	RC00004,RC00166	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_3,Acetyltransf_4
k59_1494292_2	1249480.B649_00690	4.41e-201	562.0	COG2089@1|root,COG2089@2|Bacteria,1MWG3@1224|Proteobacteria,42ME3@68525|delta/epsilon subdivisions,2YMDZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	acid synthase	pseI	-	2.5.1.56,2.5.1.97	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	-	R01804,R04435,R09841	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
k59_1852506_1	382464.ABSI01000012_gene2159	1.64e-29	118.0	COG1477@1|root,COG1477@2|Bacteria,46V70@74201|Verrucomicrobia,2IUN9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
k59_1787440_1	1165841.SULAR_10479	6.04e-113	346.0	COG1287@1|root,COG1287@2|Bacteria,1R8YG@1224|Proteobacteria,43BIB@68525|delta/epsilon subdivisions,2YT8Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Oligosaccharide transferase	-	-	2.4.99.18	ko:K07151	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	STT3
k59_1265873_1	1121374.KB891585_gene2213	1.98e-20	93.2	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,1RMMW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008654,GO:0009029,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019637,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0046401,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iBWG_1329.BWG_0767,iECDH10B_1368.ECDH10B_0985,iPC815.YPO1396	LpxK
k59_1265873_2	765910.MARPU_02880	1.42e-14	67.8	COG2835@1|root,COG2835@2|Bacteria,1N6Y2@1224|Proteobacteria,1SCFF@1236|Gammaproteobacteria,1WZ9Y@135613|Chromatiales	135613|Chromatiales	S	Belongs to the UPF0434 family	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
k59_81646_1	944547.ABLL_0482	6.96e-79	254.0	COG3540@1|root,COG3540@2|Bacteria,1MWAF@1224|Proteobacteria,430UQ@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	PhoD-like phosphatase, N-terminal domain	phoD	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD,PhoD_N
k59_1377188_1	1537917.JU82_07380	1.08e-23	92.8	2AIYJ@1|root,319GA@2|Bacteria,1Q2NX@1224|Proteobacteria,42W0X@68525|delta/epsilon subdivisions,2YQ6Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1377190_1	709032.Sulku_2224	4.91e-26	104.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,42MM1@68525|delta/epsilon subdivisions,2YN3A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	8-amino-7-oxononanoate synthase	bioF	-	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_849548_1	1156919.QWC_28815	4.43e-09	55.5	COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,2VU5Y@28216|Betaproteobacteria,3T4DS@506|Alcaligenaceae	28216|Betaproteobacteria	M	Recycling of diacylglycerol produced during the turnover of membrane phospholipid	dgkA	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
k59_849548_2	1454004.AW11_00970	5.81e-25	105.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,2VUP7@28216|Betaproteobacteria	28216|Betaproteobacteria	T	TIGRFAM Diguanylate cyclase	-	-	2.7.7.65	ko:K13069,ko:K21085	ko02026,map02026	-	R08057	-	ko00000,ko00001,ko01000	-	-	-	CHASE7,GGDEF,HAMP
k59_147597_1	1249480.B649_04905	1.86e-12	66.6	COG3842@1|root,COG3842@2|Bacteria,1RC3N@1224|Proteobacteria,42MSG@68525|delta/epsilon subdivisions,2YMX7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	ATP-binding protein	modC	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran
k59_147597_2	498761.HM1_3059	1.11e-06	48.1	COG1826@1|root,COG1826@2|Bacteria	2|Bacteria	U	protein secretion	tatA	GO:0002790,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009977,GO:0009987,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032940,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03116,ko:K03425	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
k59_1084921_2	1336245.JAGO01000012_gene1860	4.32e-27	114.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,1RMIH@1236|Gammaproteobacteria,1XHN9@135619|Oceanospirillales	135619|Oceanospirillales	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k59_907073_1	1132855.KB913035_gene2497	3.49e-86	255.0	COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,2VQ63@28216|Betaproteobacteria,2KM0N@206350|Nitrosomonadales	206350|Nitrosomonadales	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
k59_678798_1	709032.Sulku_0647	1.65e-97	301.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42S84@68525|delta/epsilon subdivisions,2YPD4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_3
k59_791266_2	159087.Daro_0109	3.65e-146	417.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,2VH51@28216|Betaproteobacteria,2KU9W@206389|Rhodocyclales	206389|Rhodocyclales	O	Peptidase U32	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
k59_1670824_1	1123318.KB904619_gene1156	7.82e-35	133.0	COG5655@1|root,COG5655@2|Bacteria,1UTSC@1239|Firmicutes,4HI0K@91061|Bacilli	91061|Bacilli	L	RePlication protein	-	-	-	-	-	-	-	-	-	-	-	-	Rep_1
k59_1559004_1	1249480.B649_00515	2.09e-128	372.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,42N69@68525|delta/epsilon subdivisions,2YN3J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
k59_203279_1	547559.Nmag_4122	1.87e-12	72.0	COG0589@1|root,arCOG00449@2157|Archaea,2XW5B@28890|Euryarchaeota,23U91@183963|Halobacteria	183963|Halobacteria	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_24739_1	387093.SUN_0422	7.45e-47	153.0	2BQJ4@1|root,32JEZ@2|Bacteria,1Q29Y@1224|Proteobacteria,42V8X@68525|delta/epsilon subdivisions,2YQIT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_791303_1	1537917.JU82_11855	5.85e-115	352.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,42MRQ@68525|delta/epsilon subdivisions,2YMJY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1g
k59_437260_1	401053.AciPR4_0437	3.83e-45	162.0	COG0477@1|root,COG2814@2|Bacteria,3Y99X@57723|Acidobacteria,2JP6K@204432|Acidobacteriia	204432|Acidobacteriia	EGP	PFAM Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
k59_969601_1	387093.SUN_1743	2.26e-44	153.0	COG2070@1|root,COG2070@2|Bacteria,1N52W@1224|Proteobacteria,42N6F@68525|delta/epsilon subdivisions,2YMD6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	2-nitropropane dioxygenase	npd	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
k59_969601_2	1244083.CSUNSWCD_1305	7.76e-29	113.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,42N2A@68525|delta/epsilon subdivisions,2YMD3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
k59_1611416_1	1282362.AEAC466_21000	7.37e-07	52.4	COG1091@1|root,COG1091@2|Bacteria,1MUXM@1224|Proteobacteria,2TSP6@28211|Alphaproteobacteria,2KGH8@204458|Caulobacterales	204458|Caulobacterales	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
k59_1611416_2	395494.Galf_2827	1.18e-65	207.0	COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,2VHA6@28216|Betaproteobacteria,44VIN@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
k59_1032821_1	398767.Glov_3716	4.65e-92	287.0	COG4584@1|root,COG4584@2|Bacteria,1MU2G@1224|Proteobacteria,42N2X@68525|delta/epsilon subdivisions,2X7GJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_1032821_2	1267535.KB906767_gene2030	1.52e-05	46.6	COG1484@1|root,COG1484@2|Bacteria,3Y4QK@57723|Acidobacteria,2JNWI@204432|Acidobacteriia	204432|Acidobacteriia	L	IstB-like ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21,IstB_IS21_ATP
k59_1201709_1	159087.Daro_0357	2.45e-133	382.0	COG0583@1|root,COG0583@2|Bacteria,1N8HZ@1224|Proteobacteria,2VSQD@28216|Betaproteobacteria,2KZZ4@206389|Rhodocyclales	206389|Rhodocyclales	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_726019_1	536232.CLM_0172	4.73e-56	186.0	COG0301@1|root,COG1293@1|root,COG0301@2|Bacteria,COG1293@2|Bacteria,1UI2N@1239|Firmicutes,247WZ@186801|Clostridia,36FM9@31979|Clostridiaceae	186801|Clostridia	HK	Thiamine biosynthesis protein (ThiI)	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,ThiI
k59_908592_1	709032.Sulku_0227	6.62e-79	238.0	2AK36@1|root,31ASY@2|Bacteria,1Q62K@1224|Proteobacteria,42W11@68525|delta/epsilon subdivisions,2YQDG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF2393)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2393
k59_1788963_1	709032.Sulku_2463	8.84e-13	68.6	COG1629@1|root,COG4771@2|Bacteria,1QWIP@1224|Proteobacteria,43BGN@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014,ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.1,1.B.14.10	-	-	OMP_b-brl_3,Plug,TonB_dep_Rec
k59_1788963_2	709032.Sulku_0854	7.54e-26	96.7	2AQJX@1|root,31FST@2|Bacteria,1QDI5@1224|Proteobacteria,432NI@68525|delta/epsilon subdivisions,2YSH6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1788963_3	709032.Sulku_0855	5.56e-75	237.0	COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,42P1M@68525|delta/epsilon subdivisions,2YN96@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Peptidase M48	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
k59_908595_1	159087.Daro_2491	1.92e-46	154.0	COG4566@1|root,COG4566@2|Bacteria,1R6VG@1224|Proteobacteria,2VKBT@28216|Betaproteobacteria,2KVS6@206389|Rhodocyclales	206389|Rhodocyclales	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_908595_2	159087.Daro_2490	4.48e-68	223.0	COG0715@1|root,COG4191@1|root,COG0715@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VMN8@28216|Betaproteobacteria,2KUPQ@206389|Rhodocyclales	206389|Rhodocyclales	T	Histidine kinase	-	-	2.7.13.3	ko:K13040	ko02020,map02020	M00514	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Phosphonate-bd
k59_438805_1	502347.ESCAB7627_3690	1.49e-16	78.6	2EBAP@1|root,335BB@2|Bacteria,1NCXU@1224|Proteobacteria,1SDBM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_377847_1	709032.Sulku_0815	1.84e-103	318.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,42MC5@68525|delta/epsilon subdivisions,2YM83@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
k59_850843_1	1537917.JU82_11355	2.68e-127	387.0	COG1629@1|root,COG4771@2|Bacteria,1QZTU@1224|Proteobacteria,43CNU@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1730884_1	1304883.KI912532_gene537	1.69e-29	113.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2VHRM@28216|Betaproteobacteria,2KV48@206389|Rhodocyclales	206389|Rhodocyclales	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_1730884_2	159087.Daro_0251	9.69e-74	228.0	COG0559@1|root,COG0559@2|Bacteria,1N54M@1224|Proteobacteria,2VIID@28216|Betaproteobacteria,2KVZ8@206389|Rhodocyclales	206389|Rhodocyclales	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_263079_1	1165841.SULAR_10444	2.62e-101	305.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,42M5U@68525|delta/epsilon subdivisions,2YMQH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	molybdopterin biosynthesis	moeA2	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
k59_263079_2	749222.Nitsa_1984	1.06e-46	153.0	COG0314@1|root,COG0314@2|Bacteria,1Q97D@1224|Proteobacteria,42REX@68525|delta/epsilon subdivisions,2YP4E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	molybdopterin converting factor	moaE	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
k59_1560938_1	1158338.JNLJ01000001_gene942	6.29e-22	97.4	COG0760@1|root,COG0760@2|Bacteria,2G5GE@200783|Aquificae	200783|Aquificae	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_2,SurA_N_3
k59_1560938_2	1158338.JNLJ01000001_gene945	9.32e-13	73.2	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF5128,NHL,TPR_11
k59_377866_1	1249480.B649_07620	4.66e-127	374.0	COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,42NTK@68525|delta/epsilon subdivisions,2YNFT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the UPF0061 (SELO) family	-	-	-	-	-	-	-	-	-	-	-	-	UPF0061
k59_793444_1	1304883.KI912532_gene1603	1.17e-101	306.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2VKXU@28216|Betaproteobacteria,2KVSV@206389|Rhodocyclales	206389|Rhodocyclales	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_26041_1	709032.Sulku_1580	1.1e-57	186.0	COG0171@1|root,COG0171@2|Bacteria,1MU9U@1224|Proteobacteria,42N86@68525|delta/epsilon subdivisions,2YNG2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source	nadE	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
k59_793447_2	1328313.DS2_02940	3.17e-18	88.6	COG2366@1|root,COG2366@2|Bacteria,1QUW6@1224|Proteobacteria,1T23A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	antibiotic biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	DM13
k59_1148848_1	1177179.A11A3_15677	2.96e-53	188.0	COG0466@1|root,COG0466@2|Bacteria,1NTR5@1224|Proteobacteria,1RPID@1236|Gammaproteobacteria,1XI68@135619|Oceanospirillales	135619|Oceanospirillales	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon-1	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_1201788_1	244582.JQAK01000001_gene1342	2.26e-33	130.0	COG3547@1|root,COG3547@2|Bacteria,1MUKH@1224|Proteobacteria,2TRPW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_793469_1	1158345.JNLL01000001_gene1261	3.44e-43	157.0	COG0755@1|root,COG0755@2|Bacteria	2|Bacteria	O	cytochrome complex assembly	ccsBA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
k59_793469_2	123214.PERMA_1444	0.000184	45.8	COG0755@1|root,COG1333@1|root,COG0755@2|Bacteria,COG1333@2|Bacteria	2|Bacteria	O	cytochrome c biogenesis protein	ccsBA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
k59_205251_1	709032.Sulku_0014	4.37e-90	279.0	COG3203@1|root,COG3203@2|Bacteria,1QZ2N@1224|Proteobacteria,42QVI@68525|delta/epsilon subdivisions,2YP28@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_317081_1	1249480.B649_04540	2.22e-63	196.0	COG3461@1|root,COG3461@2|Bacteria,1MZZN@1224|Proteobacteria,42WM3@68525|delta/epsilon subdivisions,2YRZ6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	ko:K09700	-	-	-	-	ko00000	-	-	-	-
k59_317081_2	1249480.B649_04535	1.2e-126	365.0	COG1659@1|root,COG1659@2|Bacteria,1QKHQ@1224|Proteobacteria,42UCA@68525|delta/epsilon subdivisions,2YSD1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Encapsulating protein for peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	Linocin_M18
k59_793498_1	572477.Alvin_0845	1.36e-17	82.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,1RMP9@1236|Gammaproteobacteria,1WW0V@135613|Chromatiales	135613|Chromatiales	M	lipoprotein releasing system, transmembrane protein, LolC E family	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
k59_793498_2	1123514.KB905899_gene1053	2.44e-22	94.0	COG2860@1|root,COG2860@2|Bacteria,1RHQN@1224|Proteobacteria,1S5YY@1236|Gammaproteobacteria,4610T@72273|Thiotrichales	72273|Thiotrichales	S	UPF0126 domain	-	-	-	-	-	-	-	-	-	-	-	-	UPF0126
k59_1561044_1	314345.SPV1_10019	1e-25	114.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_4
k59_1148900_1	1123514.KB905899_gene430	3.62e-82	259.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,460A8@72273|Thiotrichales	72273|Thiotrichales	NU	Secretion system protein	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
k59_1201835_1	123214.PERMA_1459	1.95e-69	228.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
k59_1854580_1	709032.Sulku_1371	1.05e-50	167.0	COG0664@1|root,COG0664@2|Bacteria,1MZZD@1224|Proteobacteria,42QUX@68525|delta/epsilon subdivisions,2YP2C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator	nssR	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
k59_1561055_1	709032.Sulku_0425	5.78e-64	209.0	COG0457@1|root,COG0457@2|Bacteria,1MXK4@1224|Proteobacteria,42PK9@68525|delta/epsilon subdivisions,2YNXX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
k59_1672414_1	1122962.AULH01000001_gene1474	1.95e-50	181.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2TQR7@28211|Alphaproteobacteria,36XJZ@31993|Methylocystaceae	28211|Alphaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	mcpT	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	Cache_3-Cache_2,HAMP,MCPsignal,PAS_3,PAS_4,PAS_8,PAS_9,dCache_1,sCache_3_3
k59_908711_1	1123514.KB905901_gene180	2.88e-51	176.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMIW@1236|Gammaproteobacteria,45ZW6@72273|Thiotrichales	72273|Thiotrichales	J	ribonuclease, Rne Rng family	-	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
k59_908711_2	572477.Alvin_2524	5.42e-34	124.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,1S41D@1236|Gammaproteobacteria,1WY2J@135613|Chromatiales	135613|Chromatiales	D	Maf-like protein	-	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
k59_1613013_2	1537917.JU82_05220	7.67e-29	104.0	COG2501@1|root,COG2501@2|Bacteria,1PFA5@1224|Proteobacteria,42XJ3@68525|delta/epsilon subdivisions,2YS84@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	S4 domain	-	-	-	ko:K14761	-	-	-	-	ko00000,ko03009	-	-	-	S4_2
k59_1613013_3	1249480.B649_01805	6.87e-173	493.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,42MHD@68525|delta/epsilon subdivisions,2YN9P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
k59_1086634_1	159087.Daro_2012	7.46e-75	228.0	COG1399@1|root,COG1399@2|Bacteria,1PGKW@1224|Proteobacteria,2VUIG@28216|Betaproteobacteria,2KX2U@206389|Rhodocyclales	206389|Rhodocyclales	S	metal-binding, possibly nucleic acid-binding protein	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
k59_1086634_2	1304883.KI912532_gene2465	3.09e-72	221.0	COG0424@1|root,COG0424@2|Bacteria,1RDA9@1224|Proteobacteria,2VQUQ@28216|Betaproteobacteria,2KW2F@206389|Rhodocyclales	206389|Rhodocyclales	D	Maf-like protein	yceF	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
k59_908720_1	522306.CAP2UW1_3137	4.31e-22	90.9	COG0745@1|root,COG0745@2|Bacteria,1RHCU@1224|Proteobacteria,2VT7U@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Pfam Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_1239225_1	1537917.JU82_01900	2.17e-92	280.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,42MD6@68525|delta/epsilon subdivisions,2YMXT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petB	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
k59_1532829_1	1249480.B649_11305	5.26e-83	261.0	COG3278@1|root,COG3278@2|Bacteria,1QAUQ@1224|Proteobacteria,42P3Q@68525|delta/epsilon subdivisions,2YNBX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the heme-copper respiratory oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	COX1
k59_1826483_1	1132855.KB913035_gene17	1e-19	83.2	2A8TC@1|root,30XWC@2|Bacteria,1PJQV@1224|Proteobacteria,2W84R@28216|Betaproteobacteria,2KNY2@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1826483_2	1132855.KB913035_gene16	8.17e-68	207.0	COG1664@1|root,COG1664@2|Bacteria,1MZN0@1224|Proteobacteria,2VTZQ@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Integral membrane protein CcmA involved in cell shape determination	ccmA	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
k59_1826483_3	1132855.KB913035_gene15	1.15e-09	55.5	COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,2VR2M@28216|Betaproteobacteria,2KMS7@206350|Nitrosomonadales	206350|Nitrosomonadales	C	Required for insertion of 4Fe-4S clusters	erpA	-	-	ko:K15724	-	-	-	-	ko00000	-	-	-	Fe-S_biosyn
k59_1590675_1	1304883.KI912532_gene485	6.08e-32	115.0	COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,2VQ7A@28216|Betaproteobacteria,2KW86@206389|Rhodocyclales	206389|Rhodocyclales	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
k59_592533_1	202956.BBNL01000038_gene228	1.77e-73	223.0	COG0080@1|root,COG0080@2|Bacteria,1RA2M@1224|Proteobacteria,1S22R@1236|Gammaproteobacteria,3NJ44@468|Moraxellaceae	1236|Gammaproteobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
k59_592533_2	1453501.JELR01000005_gene1711	9.16e-113	329.0	COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,1RMDW@1236|Gammaproteobacteria,4649G@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
k59_592533_3	857087.Metme_3825	4.27e-47	157.0	COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,1S286@1236|Gammaproteobacteria,1XEHY@135618|Methylococcales	135618|Methylococcales	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
k59_592533_4	1385420.FRA_35c08050	1.87e-48	158.0	COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,1S5V7@1236|Gammaproteobacteria,460RJ@72273|Thiotrichales	72273|Thiotrichales	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
k59_592533_5	159087.Daro_0312	2.18e-18	84.3	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,2VHF3@28216|Betaproteobacteria,2KV0Q@206389|Rhodocyclales	206389|Rhodocyclales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_63678_1	546274.EIKCOROL_02184	4.44e-74	228.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,2VQ06@28216|Betaproteobacteria,2KQ3U@206351|Neisseriales	206351|Neisseriales	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
k59_1239258_1	709032.Sulku_2535	5.29e-176	494.0	COG0208@1|root,COG0208@2|Bacteria,1MWUS@1224|Proteobacteria,42ME8@68525|delta/epsilon subdivisions,2YN4W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdB	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
k59_535034_1	159087.Daro_3815	9.6e-80	245.0	COG0543@1|root,COG1018@1|root,COG0543@2|Bacteria,COG1018@2|Bacteria,1MXPX@1224|Proteobacteria,2VI2P@28216|Betaproteobacteria,2KY8B@206389|Rhodocyclales	206389|Rhodocyclales	C	COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases	-	-	1.18.1.3	ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,map00623,map00920,map01100,map01120,map01220	M00538	R02550,R03562,R05666,R09513	RC00269,RC00490,RC02556	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
k59_827862_1	1150621.SMUL_0080	5.35e-06	48.1	COG0715@1|root,COG0834@1|root,COG2199@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG2199@2|Bacteria,1RGCV@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	yeaI	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0032879,GO:0040012,GO:0040013,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051270,GO:0051271,GO:0065007,GO:0071944,GO:1902021,GO:1902201,GO:2000145,GO:2000146	2.7.7.65	ko:K20959	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_853	CHASE,EAL,GGDEF,MASE4,NMT1,PAS,PAS_3
k59_827862_2	1537917.JU82_10440	1.19e-56	184.0	COG0697@1|root,COG0697@2|Bacteria,1MZXM@1224|Proteobacteria,42ME7@68525|delta/epsilon subdivisions,2YMBW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EG	membrane	-	-	-	ko:K15270	-	-	-	-	ko00000,ko02000	2.A.7.3.7	-	-	EamA
k59_1590700_1	1502770.JQMG01000001_gene967	4.28e-47	167.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,2VIA1@28216|Betaproteobacteria,2KKTM@206350|Nitrosomonadales	206350|Nitrosomonadales	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
k59_1590700_2	1132855.KB913035_gene27	3.26e-38	128.0	COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,2VVUH@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
k59_708973_1	1249480.B649_04830	5.47e-46	161.0	2AJS6@1|root,31AEF@2|Bacteria,1Q5FI@1224|Proteobacteria,4315Z@68525|delta/epsilon subdivisions,2YSA1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1239286_1	1249480.B649_09650	7.25e-163	460.0	COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,42N3E@68525|delta/epsilon subdivisions,2YMM7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	PFAM NADH ubiquinone oxidoreductase, 20 Kd subunit	hupS	-	1.12.99.6	ko:K06282	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6
k59_1061717_1	709032.Sulku_1387	1.03e-145	427.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,42PUI@68525|delta/epsilon subdivisions,2YN3E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	PFAM TrkA-N domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2,TrkA_N
k59_1707888_1	709032.Sulku_1130	0.000146	42.7	COG0352@1|root,COG0352@2|Bacteria,1Q57E@1224|Proteobacteria,42T8S@68525|delta/epsilon subdivisions,2YPQM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Thiamine monophosphate synthase	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
k59_1707888_2	1537917.JU82_09295	1.44e-55	178.0	COG0352@1|root,COG0352@2|Bacteria,1Q57E@1224|Proteobacteria,42T8S@68525|delta/epsilon subdivisions,2YPQM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Thiamine monophosphate synthase	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
k59_1707888_3	709032.Sulku_1129	2.4e-61	195.0	COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,42MAB@68525|delta/epsilon subdivisions,2YN34@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
k59_827885_1	159087.Daro_2390	2.26e-37	134.0	COG2834@1|root,COG2834@2|Bacteria,1RE9C@1224|Proteobacteria,2VPGB@28216|Betaproteobacteria,2KVYY@206389|Rhodocyclales	206389|Rhodocyclales	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
k59_827885_2	351627.Csac_0646	8.55e-11	62.0	COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,248Z6@186801|Clostridia,42F4Z@68295|Thermoanaerobacterales	186801|Clostridia	V	PFAM ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_1121478_1	177437.HRM2_00460	0.000959	44.3	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,42PKU@68525|delta/epsilon subdivisions,2WM5K@28221|Deltaproteobacteria,2MIM9@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798,ko:K15727	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1,8.A.1.2.1	-	-	DUF3347,HlyD_D23
k59_1826540_1	877455.Metbo_1099	2.15e-14	77.4	COG0784@1|root,arCOG06537@2157|Archaea	2157|Archaea	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_1414648_1	1304883.KI912532_gene574	4.28e-160	457.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,2VHXR@28216|Betaproteobacteria,2KURZ@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
k59_1004104_1	1123518.ARWI01000001_gene1394	1.24e-102	308.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RPAB@1236|Gammaproteobacteria,4612S@72273|Thiotrichales	72273|Thiotrichales	C	Cysteine-rich domain	-	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_7,Fer4_8
k59_1532906_1	709032.Sulku_0882	8.39e-106	316.0	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,42N01@68525|delta/epsilon subdivisions,2YMG2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
k59_1649230_1	159087.Daro_3082	4.35e-108	325.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,2VH79@28216|Betaproteobacteria,2KU6P@206389|Rhodocyclales	206389|Rhodocyclales	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
k59_240286_1	699218.HMPREF0889_1166	5.42e-11	64.3	COG1043@1|root,COG1043@2|Bacteria,1TQRI@1239|Firmicutes,4H2NG@909932|Negativicutes	909932|Negativicutes	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep,Hexapep_2
k59_7114_1	1537917.JU82_08475	3.91e-14	67.4	COG0680@1|root,COG0680@2|Bacteria,1N3AS@1224|Proteobacteria,43AZK@68525|delta/epsilon subdivisions,2YP7W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Hydrogenase maturation protease	-	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
k59_7114_2	387092.NIS_0965	3.32e-61	194.0	COG1969@1|root,COG1969@2|Bacteria,1MU87@1224|Proteobacteria,42NQ3@68525|delta/epsilon subdivisions,2YMRF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Ni Fe-hydrogenase, b-type cytochrome subunit	-	-	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
k59_592606_1	397945.Aave_0898	3.01e-107	320.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,2VHK9@28216|Betaproteobacteria,4AAY9@80864|Comamonadaceae	28216|Betaproteobacteria	H	PFAM aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_1121516_1	1249480.B649_03285	2.41e-106	317.0	COG2199@1|root,COG3706@2|Bacteria,1NC00@1224|Proteobacteria,43DI1@68525|delta/epsilon subdivisions,2YTIQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	diguanylate cyclase	-	-	2.7.7.65	ko:K13590	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF
k59_1179815_1	709032.Sulku_0622	2.87e-135	385.0	COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,42N6I@68525|delta/epsilon subdivisions,2YN8H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
k59_1179815_2	1537917.JU82_09780	2.19e-34	130.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42YH8@68525|delta/epsilon subdivisions,2YRAU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
k59_1826598_1	401053.AciPR4_2920	2.77e-30	119.0	COG2199@1|root,COG3706@2|Bacteria,3Y6ZN@57723|Acidobacteria,2JKFD@204432|Acidobacteriia	204432|Acidobacteriia	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,MASE1
k59_827946_1	709032.Sulku_0801	9.72e-26	98.6	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	ohrR	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
k59_827946_2	1249480.B649_08090	3.06e-28	109.0	COG0726@1|root,COG0726@2|Bacteria,1MWUE@1224|Proteobacteria,42QSJ@68525|delta/epsilon subdivisions,2YTM4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
k59_709023_1	1123517.JOMR01000001_gene1483	9.6e-61	201.0	COG0524@1|root,COG2146@1|root,COG0524@2|Bacteria,COG2146@2|Bacteria,1MWX4@1224|Proteobacteria,1RQW6@1236|Gammaproteobacteria,460KJ@72273|Thiotrichales	72273|Thiotrichales	G	PFAM pfkB family carbohydrate kinase	-	-	2.7.1.3	ko:K00846	ko00051,ko01100,ko01120,map00051,map01100,map01120	-	R00866,R03819	RC00002,RC00017,RC00608	ko00000,ko00001,ko01000,ko04147	-	-	-	PfkB,Rieske
k59_240319_1	509191.AEDB02000018_gene227	3.71e-12	71.6	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TSKR@1239|Firmicutes,24AFC@186801|Clostridia,3WHHR@541000|Ruminococcaceae	186801|Clostridia	T	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
k59_240319_2	1123326.JFBL01000001_gene1382	9.65e-06	47.8	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42TH4@68525|delta/epsilon subdivisions,2YRFX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_3
k59_1296752_1	335543.Sfum_3292	3.15e-10	63.5	COG2203@1|root,COG2204@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2204@2|Bacteria,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,42MEJ@68525|delta/epsilon subdivisions,2X71A@28221|Deltaproteobacteria,2MSKQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,GGDEF,HD,Response_reg
k59_1296752_2	1565314.OA34_06750	7.48e-53	179.0	COG0840@1|root,COG0840@2|Bacteria,1R5W9@1224|Proteobacteria,42PPM@68525|delta/epsilon subdivisions,2YN9B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	methyl-accepting chemotaxis protein	tlpD	-	-	-	-	-	-	-	-	-	-	-	CZB,MCPsignal
k59_1121543_1	283942.IL2616	7.32e-93	294.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,1RMVN@1236|Gammaproteobacteria,2QF0Q@267893|Idiomarinaceae	1236|Gammaproteobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009987,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0034654,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iE2348C_1286.E2348C_4039,iEC042_1314.EC042_4115,iECIAI39_1322.ECIAI39_4333,iECNA114_1301.ECNA114_3878,iECOK1_1307.ECOK1_4178,iECSF_1327.ECSF_3577,iECUMN_1333.ECUMN_4259,iEcSMS35_1347.EcSMS35_4097,iLF82_1304.LF82_0844,iNRG857_1313.NRG857_18570,iSFV_1184.SFV_3755,iSF_1195.SF3809,iSFxv_1172.SFxv_4151,iS_1188.S3959,iUMN146_1321.UM146_18835,iUTI89_1310.UTI89_C4281	GATase_6,SIS
k59_1355365_1	1333856.L686_19795	1.39e-09	55.5	COG0526@1|root,COG0526@2|Bacteria,1MZ6D@1224|Proteobacteria,1S6KZ@1236|Gammaproteobacteria,1Z35W@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	CO	COG0526 Thiol-disulfide isomerase and thioredoxins	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
k59_1355365_2	159087.Daro_4189	7e-39	130.0	291Q9@1|root,2ZPAD@2|Bacteria,1P9II@1224|Proteobacteria,2W59Y@28216|Betaproteobacteria,2KZG1@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1355365_3	107635.AZUO01000001_gene2051	1.2e-08	54.3	2D71I@1|root,32TN6@2|Bacteria,1N2CA@1224|Proteobacteria,2UEWY@28211|Alphaproteobacteria,36YSI@31993|Methylocystaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1239398_1	709032.Sulku_1886	1.18e-117	338.0	COG0560@1|root,COG0560@2|Bacteria,1MWA3@1224|Proteobacteria,42NIR@68525|delta/epsilon subdivisions,2YNHV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	phosphoserine phosphatase	serB	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD,Hydrolase
k59_1355382_2	1165841.SULAR_05028	3.53e-118	349.0	COG0677@1|root,COG0677@2|Bacteria,1QV0P@1224|Proteobacteria,43BN8@68525|delta/epsilon subdivisions,2YNJZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.336	ko:K02472	ko00520,ko05111,map00520,map05111	-	R03317	RC00291	ko00000,ko00001,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_1414733_1	159087.Daro_2266	3.22e-13	69.3	2D91J@1|root,32TSD@2|Bacteria,1N65Q@1224|Proteobacteria,2VUNJ@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1414733_2	338969.Rfer_3638	1.16e-24	101.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,2VH1F@28216|Betaproteobacteria,4AC8G@80864|Comamonadaceae	28216|Betaproteobacteria	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD_5
k59_592660_1	1165841.SULAR_03742	9.73e-54	194.0	COG3387@1|root,COG3387@2|Bacteria,1MXWR@1224|Proteobacteria	1224|Proteobacteria	G	phosphorylase kinase alphabeta	ygeQ	-	-	ko:K07190	ko04020,ko04910,ko04922,map04020,map04910,map04922	-	-	-	ko00000,ko00001	-	-	-	Glyco_hydro_15
k59_535166_1	367737.Abu_0455	1.77e-53	191.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,43CHE@68525|delta/epsilon subdivisions,2YRKK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	HAMP domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
k59_475709_1	497321.C664_12575	1.95e-76	244.0	COG0189@1|root,COG0454@1|root,COG0189@2|Bacteria,COG0456@2|Bacteria,1MVN2@1224|Proteobacteria,2VJMQ@28216|Betaproteobacteria,2KVQN@206389|Rhodocyclales	206389|Rhodocyclales	HJ	ATP-grasp domain	-	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,CPSase_L_D2,Mur_ligase_C,Mur_ligase_M,RimK
k59_1593214_2	1249480.B649_04225	2.23e-139	401.0	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,42PA2@68525|delta/epsilon subdivisions,2YN18@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
k59_1417542_1	709032.Sulku_0582	9.38e-85	254.0	29VYJ@1|root,30HGQ@2|Bacteria,1Q33E@1224|Proteobacteria,42WQE@68525|delta/epsilon subdivisions,2YQMM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_242772_1	387093.SUN_0547	1.18e-134	407.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2YMAI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k59_1769087_1	1165841.SULAR_10379	4.86e-57	181.0	COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,42R1J@68525|delta/epsilon subdivisions,2YT60@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
k59_1769087_2	1244083.CSUNSWCD_1161	3.2e-56	177.0	COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,42SHZ@68525|delta/epsilon subdivisions,2YPDZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
k59_710940_1	768671.ThimaDRAFT_2299	2.42e-39	137.0	COG3223@1|root,COG3223@2|Bacteria,1N0MS@1224|Proteobacteria,1S9SN@1236|Gammaproteobacteria,1WZ2R@135613|Chromatiales	135613|Chromatiales	S	Belongs to the PsiE family	-	-	-	ko:K13256	-	-	-	-	ko00000	-	-	-	PsiE
k59_710940_2	1123514.KB905899_gene1850	1.15e-47	158.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,1RN3K@1236|Gammaproteobacteria,46063@72273|Thiotrichales	72273|Thiotrichales	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
k59_1299112_1	1537917.JU82_06815	0.000108	43.5	COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,42NTK@68525|delta/epsilon subdivisions,2YNFT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the UPF0061 (SELO) family	-	-	-	-	-	-	-	-	-	-	-	-	UPF0061
k59_1299112_2	1249480.B649_07615	2.11e-31	123.0	COG1315@1|root,COG1315@2|Bacteria,1R5P6@1224|Proteobacteria,42MAS@68525|delta/epsilon subdivisions,2YM7Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Flagellar Assembly Protein A	-	-	-	-	-	-	-	-	-	-	-	-	FapA
k59_1242434_2	324925.Ppha_0484	0.000398	44.7	COG5652@1|root,COG5652@2|Bacteria,1FFNH@1090|Chlorobi	1090|Chlorobi	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
k59_126230_1	395494.Galf_1757	3.35e-50	176.0	COG3957@1|root,COG3957@2|Bacteria,1MVSE@1224|Proteobacteria,2VIGM@28216|Betaproteobacteria,44W5X@713636|Nitrosomonadales	28216|Betaproteobacteria	G	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase	xfp	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
k59_595389_1	1444770.AF72_08540	2.58e-12	70.1	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RNE4@1236|Gammaproteobacteria,1X4NW@135614|Xanthomonadales	135614|Xanthomonadales	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
k59_595389_2	68170.KL590485_gene8245	1.63e-06	52.8	COG1253@1|root,COG1253@2|Bacteria,2GKN5@201174|Actinobacteria,4DZCJ@85010|Pseudonocardiales	201174|Actinobacteria	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
k59_1475985_1	1249480.B649_01935	3.33e-64	204.0	COG0745@1|root,COG0745@2|Bacteria,1QUJR@1224|Proteobacteria,42NQS@68525|delta/epsilon subdivisions,2YN0F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_1475994_1	1366050.N234_34485	3.33e-12	67.4	28H52@1|root,2Z7HQ@2|Bacteria,1MXTF@1224|Proteobacteria,2VJJ3@28216|Betaproteobacteria,1K50G@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1329)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1329
k59_1475994_2	62928.azo2256	3.19e-38	134.0	COG2010@1|root,COG2010@2|Bacteria,1N8E4@1224|Proteobacteria,2VWFV@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_595423_1	1537917.JU82_07200	8.15e-133	384.0	COG0642@1|root,COG0642@2|Bacteria,1NXDJ@1224|Proteobacteria,42KZV@68525|delta/epsilon subdivisions,2YM8J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	flgS	-	2.7.13.3	ko:K02482,ko:K07710	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_595423_2	1537917.JU82_07195	2.62e-31	119.0	COG1362@1|root,COG1362@2|Bacteria,1NT1D@1224|Proteobacteria,42MN0@68525|delta/epsilon subdivisions,2YRFV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	M18 family aminopeptidase	-	-	3.4.11.21	ko:K01267	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	Peptidase_M18
k59_538179_1	1537917.JU82_09730	1.88e-127	372.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,42M3R@68525|delta/epsilon subdivisions,2YN91@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
k59_1182290_1	709032.Sulku_2342	1.04e-65	223.0	COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,1QUIU@1224|Proteobacteria,42M7I@68525|delta/epsilon subdivisions,2YMX0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG3893 inactivated superfamily I helicase	addB	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
k59_1535750_2	709032.Sulku_0638	1.58e-55	177.0	COG1331@1|root,COG1331@2|Bacteria,1N55I@1224|Proteobacteria,42VTZ@68525|delta/epsilon subdivisions,2YQJ6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Highly conserved protein containing a thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH
k59_711002_1	159087.Daro_0030	1.42e-89	283.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,2VIDI@28216|Betaproteobacteria,2KV2P@206389|Rhodocyclales	206389|Rhodocyclales	T	Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k59_655479_2	1415778.JQMM01000001_gene43	2.02e-62	206.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,1RNM1@1236|Gammaproteobacteria,1J4XV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	GO:0001073,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004177,GO:0005488,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006351,GO:0006355,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009056,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016787,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042150,GO:0043170,GO:0043171,GO:0043244,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140096,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1903506,GO:2000112,GO:2001141	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
k59_1593303_1	1165841.SULAR_06363	6.32e-68	209.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,42SJW@68525|delta/epsilon subdivisions,2YNXS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	sigma 54 modulation protein ribosomal protein S30EA	raiA	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
k59_1593303_2	749222.Nitsa_0410	1.16e-55	183.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
k59_1124520_1	387093.SUN_1561	7.45e-64	197.0	COG0789@1|root,COG0789@2|Bacteria,1N948@1224|Proteobacteria,42SGY@68525|delta/epsilon subdivisions,2YPH4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator	hspR	-	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
k59_1124520_2	1123325.JHUV01000013_gene1606	1.18e-18	86.3	COG2199@1|root,COG3706@2|Bacteria,2G51D@200783|Aquificae	200783|Aquificae	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_9532_1	1537917.JU82_11685	1.58e-138	408.0	COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,42N42@68525|delta/epsilon subdivisions,2YMNR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
k59_1855643_1	159087.Daro_2338	3.55e-112	335.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,2VH9X@28216|Betaproteobacteria,2KVFJ@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
k59_1562140_1	519989.ECTPHS_12438	2.78e-90	278.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,1RN1G@1236|Gammaproteobacteria,1WW7C@135613|Chromatiales	135613|Chromatiales	E	Belongs to the aspartokinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
k59_1269090_3	159087.Daro_1597	5.46e-33	122.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2VMMZ@28216|Betaproteobacteria,2KUK0@206389|Rhodocyclales	206389|Rhodocyclales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
k59_909527_1	1249480.B649_08650	3.33e-37	142.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2YN6Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DNA mismatch repair MutS family	-	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_III,MutS_V
k59_1036259_1	85643.Tmz1t_2022	3.55e-45	156.0	COG1242@1|root,COG1242@2|Bacteria,1MUYF@1224|Proteobacteria,2VI70@28216|Betaproteobacteria,2KWQ9@206389|Rhodocyclales	206389|Rhodocyclales	S	Radical_SAM C-terminal domain	-	-	-	ko:K07139	-	-	-	-	ko00000	-	-	-	Radical_SAM,Radical_SAM_C
k59_1036259_2	1123487.KB892844_gene845	4.63e-25	103.0	COG1032@1|root,COG1032@2|Bacteria,1MUMS@1224|Proteobacteria,2VZ32@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k59_972740_1	1249480.B649_09245	2.22e-106	315.0	COG0147@1|root,COG0147@2|Bacteria,1R5Y8@1224|Proteobacteria,42P2B@68525|delta/epsilon subdivisions,2YMFR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EH	component I	pabB	-	2.6.1.85	ko:K01665	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	Chorismate_bind
k59_972740_2	1249480.B649_09250	1.65e-26	98.6	COG1555@1|root,COG1555@2|Bacteria,1PU4P@1224|Proteobacteria,42VEG@68525|delta/epsilon subdivisions,2YQRQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Helix-hairpin-helix motif	-	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3
k59_972741_1	387093.SUN_0119	1.96e-127	380.0	COG1070@1|root,COG1070@2|Bacteria,1MWS5@1224|Proteobacteria,43CSA@68525|delta/epsilon subdivisions,2YNV8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	COG1070 Sugar (pentulose and hexulose)	-	-	2.7.1.189	ko:K11216	ko02024,map02024	-	R11183	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
k59_150216_1	771875.Ferpe_1664	2.2e-54	199.0	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG3829@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,2GCUP@200918|Thermotogae	200918|Thermotogae	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,HisKA_7TM,Hpt,PAS_4,PAS_9,Response_reg
k59_378754_1	1249480.B649_01010	5.79e-16	75.5	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,42M3Y@68525|delta/epsilon subdivisions,2YMD5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
k59_378754_2	1537917.JU82_10755	7.76e-123	358.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,42NNS@68525|delta/epsilon subdivisions,2YMQW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
k59_264028_1	582744.Msip34_1199	4.37e-13	72.0	COG3146@1|root,COG3146@2|Bacteria,1R5A3@1224|Proteobacteria,2VNZT@28216|Betaproteobacteria,2KP30@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Peptidogalycan biosysnthesis/recognition	-	-	-	-	-	-	-	-	-	-	-	-	FemAB_like
k59_264028_2	1136138.JH604622_gene1882	1.49e-10	59.7	COG2076@1|root,COG2076@2|Bacteria,1N7QD@1224|Proteobacteria,1SDS0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane	arnE	-	-	ko:K12962	ko01503,map01503	M00721	-	-	ko00000,ko00001,ko00002,ko01005,ko02000	2.A.7.22	-	-	EamA,Multi_Drug_Res
k59_1496624_1	373994.Riv7116_3197	7.22e-09	62.8	COG0515@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GBKM@1117|Cyanobacteria,1HJ09@1161|Nostocales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,Pkinase
k59_1317501_1	1537917.JU82_10615	6.97e-141	412.0	COG1032@1|root,COG1032@2|Bacteria,1Q5NG@1224|Proteobacteria,42N2D@68525|delta/epsilon subdivisions,2YNAR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4080,Radical_SAM
k59_1317501_2	709032.Sulku_1035	9.96e-21	87.8	COG2353@1|root,COG2353@2|Bacteria,1N4PP@1224|Proteobacteria,42U5U@68525|delta/epsilon subdivisions,2YQF5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
k59_1036343_1	387093.SUN_0615	2.41e-26	106.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,42MHK@68525|delta/epsilon subdivisions,2YMEV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
k59_1036343_2	1165841.SULAR_00345	2e-67	210.0	28WAS@1|root,2ZIB8@2|Bacteria,1NBB7@1224|Proteobacteria,42P2G@68525|delta/epsilon subdivisions,2YNQ5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_503131_1	709032.Sulku_1742	7.45e-101	312.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42PTS@68525|delta/epsilon subdivisions,2YNBM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_1269195_1	159087.Daro_2440	1.66e-46	161.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,2VJ7A@28216|Betaproteobacteria,2KUVI@206389|Rhodocyclales	206389|Rhodocyclales	M	UDP binding domain	-	-	-	ko:K02474	ko00520,map00520	-	R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_1269195_2	1304883.KI912532_gene2930	7.91e-18	83.2	COG0741@1|root,COG0790@1|root,COG0741@2|Bacteria,COG0790@2|Bacteria,1MZ4X@1224|Proteobacteria,2VM6E@28216|Betaproteobacteria,2KV7Z@206389|Rhodocyclales	206389|Rhodocyclales	M	Lytic transglycosylase	-	-	-	-	-	-	-	-	-	-	-	-	SLT,Sel1
k59_1562254_1	709032.Sulku_1779	9.47e-87	262.0	COG2199@1|root,COG2199@2|Bacteria,1Q2N5@1224|Proteobacteria,42VZ7@68525|delta/epsilon subdivisions,2YQIC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG2199 FOG GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_1562254_2	709032.Sulku_1788	3.94e-09	56.6	COG1979@1|root,COG1979@2|Bacteria,1QUBJ@1224|Proteobacteria,42MPI@68525|delta/epsilon subdivisions,2YMD7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	dehydrogenase	-	-	-	ko:K08325	ko00640,map00640	-	R02528	RC00739	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
k59_620256_1	944546.ABED_1640	1.66e-93	286.0	COG1696@1|root,COG1696@2|Bacteria,1MUXN@1224|Proteobacteria,42MIR@68525|delta/epsilon subdivisions,2YN3N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Alginate O-acetylation protein	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
k59_1614062_1	159087.Daro_1925	5.98e-95	305.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,2VHTE@28216|Betaproteobacteria,2KVJB@206389|Rhodocyclales	206389|Rhodocyclales	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
k59_1317520_1	387093.SUN_2349	2.04e-36	129.0	COG0607@1|root,COG4802@1|root,COG0607@2|Bacteria,COG4802@2|Bacteria,1QYD3@1224|Proteobacteria,42PN1@68525|delta/epsilon subdivisions,2YMYE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CP	PFAM Ferredoxin thioredoxin reductase catalytic beta chain	-	-	-	-	-	-	-	-	-	-	-	-	FeThRed_B,Rhodanese
k59_1317520_2	1165841.SULAR_08177	1.05e-65	201.0	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,42REF@68525|delta/epsilon subdivisions,2YP4V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
k59_1855799_1	709032.Sulku_2083	1.06e-103	322.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,42KZ9@68525|delta/epsilon subdivisions,2YMS4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_1379910_1	1537917.JU82_06500	6.38e-149	429.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,42MJ7@68525|delta/epsilon subdivisions,2YMWU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	COG0402 Cytosine deaminase and related metal-dependent	orf1	-	3.5.4.40	ko:K20810	ko00130,ko01110,map00130,map01110	-	R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k59_1562308_1	1123517.JOMR01000001_gene1158	2.6e-42	145.0	COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,1S4N8@1236|Gammaproteobacteria,460HE@72273|Thiotrichales	72273|Thiotrichales	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
k59_1562308_2	1136177.KCA1_1153	8.53e-05	45.4	COG0225@1|root,COG0225@2|Bacteria,1TS05@1239|Firmicutes,4HAPI@91061|Bacilli,3FC52@33958|Lactobacillaceae	91061|Bacilli	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	mrsA1	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	EntA_Immun,PMSR
k59_565320_2	1485545.JQLW01000001_gene1444	1.94e-57	191.0	COG0381@1|root,COG0381@2|Bacteria,1MWZN@1224|Proteobacteria	1224|Proteobacteria	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	wecB	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
k59_1269274_1	709032.Sulku_2496	2.31e-137	394.0	COG3439@1|root,COG3439@2|Bacteria,1RBWN@1224|Proteobacteria,43BBQ@68525|delta/epsilon subdivisions,2YT7G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1562339_1	1380387.JADM01000020_gene3735	5.67e-52	182.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,1RMGA@1236|Gammaproteobacteria,1XHNC@135619|Oceanospirillales	135619|Oceanospirillales	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
k59_1562339_2	1234364.AMSF01000085_gene2962	5.67e-45	151.0	COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,1S61A@1236|Gammaproteobacteria,1X6H1@135614|Xanthomonadales	135614|Xanthomonadales	S	Glutamyl-tRNA amidotransferase	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
k59_1562339_3	90814.KL370891_gene1766	3.01e-30	108.0	COG0828@1|root,COG0828@2|Bacteria,1MZCC@1224|Proteobacteria,1S8QZ@1236|Gammaproteobacteria,46141@72273|Thiotrichales	72273|Thiotrichales	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
k59_972892_1	1165841.SULAR_07875	2.57e-101	305.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,42NKY@68525|delta/epsilon subdivisions,2YN43@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
k59_909694_1	1249480.B649_07325	2.94e-114	342.0	COG0668@1|root,COG0668@2|Bacteria,1PMY3@1224|Proteobacteria,42M4K@68525|delta/epsilon subdivisions,2YMAQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
k59_1087696_1	709032.Sulku_0488	1.36e-165	481.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,42NN7@68525|delta/epsilon subdivisions,2YMKH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
k59_1562372_1	709032.Sulku_0360	4.95e-180	508.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,42MJY@68525|delta/epsilon subdivisions,2YMA5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
k59_1269348_1	390874.Tpet_1365	3.91e-35	136.0	COG0840@1|root,COG0840@2|Bacteria,2GDZI@200918|Thermotogae	200918|Thermotogae	NT	Methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,dCache_2,sCache_2
k59_1855912_1	666681.M301_1786	4.36e-56	183.0	COG4359@1|root,COG4359@2|Bacteria,1REUD@1224|Proteobacteria,2VJXZ@28216|Betaproteobacteria,2KNSD@206350|Nitrosomonadales	206350|Nitrosomonadales	E	PFAM HAD-superfamily hydrolase subfamily IB	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1444953_1	118005.AWNK01000007_gene783	7.32e-30	123.0	COG5001@1|root,COG5001@2|Bacteria	2|Bacteria	T	cyclic-guanylate-specific phosphodiesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	5TM-5TMR_LYT,EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
k59_1790125_1	525898.Sdel_1045	6.95e-44	161.0	COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,1QTS5@1224|Proteobacteria,42MPY@68525|delta/epsilon subdivisions,2YMV7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	phosphate acetyltransferase	pta	-	2.3.1.8	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,DRTGG,PTA_PTB
k59_1036537_1	387093.SUN_1762	2.28e-61	202.0	COG1729@1|root,COG1729@2|Bacteria,1NG81@1224|Proteobacteria,42R1Z@68525|delta/epsilon subdivisions,2YNY7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	repeat protein	ybgF	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_6
k59_1855924_1	323848.Nmul_A1360	2.14e-11	64.3	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2VI01@28216|Betaproteobacteria,371RJ@32003|Nitrosomonadales	28216|Betaproteobacteria	E	PFAM aminotransferase, class I	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_1855924_3	247634.GPB2148_3515	2.07e-29	116.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RP0W@1236|Gammaproteobacteria,1J4EQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor	bioA	GO:0003674,GO:0003824,GO:0004015,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iUTI89_1310.UTI89_C0772,iZ_1308.Z0993	Aminotran_3
k59_1150062_1	709032.Sulku_0625	6.09e-115	335.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,43B2E@68525|delta/epsilon subdivisions,2YN33@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	peptidylprolyl isomerase	peb4	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
k59_1269376_1	339670.Bamb_2281	1.54e-26	113.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,2VJYV@28216|Betaproteobacteria,1JZXQ@119060|Burkholderiaceae	28216|Betaproteobacteria	C	NADH-quinone oxidoreductase	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
k59_1562443_2	1249480.B649_06610	1.16e-57	183.0	COG2077@1|root,COG2077@2|Bacteria,1Q5Y2@1224|Proteobacteria,4321Y@68525|delta/epsilon subdivisions,2YS92@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	-	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	-
k59_1855970_1	1249480.B649_07250	4.28e-125	370.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,42M2G@68525|delta/epsilon subdivisions,2YMS0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
k59_851792_1	1132855.KB913035_gene2097	2.27e-53	174.0	COG0731@1|root,COG0731@2|Bacteria,1QG36@1224|Proteobacteria,2VK7Z@28216|Betaproteobacteria,2KN1Y@206350|Nitrosomonadales	206350|Nitrosomonadales	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k59_851792_2	1132855.KB913035_gene2098	4.39e-51	167.0	COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,2VH04@28216|Betaproteobacteria,2KM5E@206350|Nitrosomonadales	206350|Nitrosomonadales	K	helix_turn_helix, cAMP Regulatory protein	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
k59_84155_1	67275.JOAP01000014_gene4623	8.84e-81	260.0	COG2216@1|root,COG2216@2|Bacteria,2GIWT@201174|Actinobacteria	201174|Actinobacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system	kdpB	-	3.6.3.12	ko:K01547	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	E1-E2_ATPase,Hydrolase
k59_682300_1	709032.Sulku_0619	2.8e-75	238.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,42N30@68525|delta/epsilon subdivisions,2YMCR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
k59_1673469_1	1485545.JQLW01000006_gene248	8.96e-28	117.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07709,ko:K19694	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HTH_18,HisKA,PAS,PAS_3,PAS_4,PAS_9,Reg_prop,Response_reg,Y_Y_Y
k59_317897_1	749222.Nitsa_1700	4.76e-73	233.0	COG2252@1|root,COG2252@2|Bacteria,1MUV0@1224|Proteobacteria,42MAE@68525|delta/epsilon subdivisions,2YM94@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	permease	-	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
k59_1562494_2	1537917.JU82_08635	1.09e-76	236.0	COG1578@1|root,COG1578@2|Bacteria,1RI11@1224|Proteobacteria,42RA1@68525|delta/epsilon subdivisions,2YNYT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function DUF89	-	-	-	ko:K09116	-	-	-	-	ko00000	-	-	-	DUF89
k59_909821_1	1249480.B649_01880	1.22e-69	224.0	COG2433@1|root,COG2433@2|Bacteria,1QW3W@1224|Proteobacteria,42RB0@68525|delta/epsilon subdivisions,2YNE9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Pfam Transposase IS66	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
k59_1496844_1	305700.B447_17149	7.83e-81	252.0	28JAH@1|root,2Z95A@2|Bacteria,1MXKT@1224|Proteobacteria,2VI69@28216|Betaproteobacteria,2KW5D@206389|Rhodocyclales	206389|Rhodocyclales	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
k59_1383198_1	1249480.B649_00145	2.94e-35	122.0	COG2608@1|root,COG2608@2|Bacteria,1N4NF@1224|Proteobacteria,42VJZ@68525|delta/epsilon subdivisions,2YQ8A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Heavy-metal-associated domain	-	-	-	ko:K08364	-	-	-	-	ko00000,ko02000	1.A.72.1	-	-	HMA
k59_1040313_1	709032.Sulku_1369	1.08e-59	189.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,42QXV@68525|delta/epsilon subdivisions,2YNXY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
k59_1040313_2	1249480.B649_06490	2.86e-74	236.0	COG0683@1|root,COG0683@2|Bacteria,1Q7JN@1224|Proteobacteria,42NDA@68525|delta/epsilon subdivisions,2YN6T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	leucine binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1320348_1	1165841.SULAR_00120	4.64e-168	506.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2YMA1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
k59_798384_1	709032.Sulku_2140	4.06e-126	369.0	COG3642@1|root,COG3642@2|Bacteria,1NSBH@1224|Proteobacteria,42Q7Z@68525|delta/epsilon subdivisions,2YN3B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	lipopolysaccharide core region biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1676180_1	672.VV93_v1c06920	1.37e-100	304.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,1RMY3@1236|Gammaproteobacteria,1XTCG@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008479,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
k59_266914_1	452652.KSE_35670	1.12e-14	77.8	arCOG12551@1|root,2Z9WJ@2|Bacteria,2I85G@201174|Actinobacteria,2M4IH@2063|Kitasatospora	201174|Actinobacteria	S	Putative  PD-(D/E)XK family member, (DUF4420)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4420
k59_1090939_1	709032.Sulku_0129	2.87e-84	276.0	COG0439@1|root,COG1984@1|root,COG2049@1|root,COG0439@2|Bacteria,COG1984@2|Bacteria,COG2049@2|Bacteria,1MU4H@1224|Proteobacteria,42P49@68525|delta/epsilon subdivisions,2YNRZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EI	Allophanate hydrolase subunit 1	-	-	6.3.4.6	ko:K01941	ko00220,ko00791,ko01100,map00220,map00791,map01100	-	R00774	RC00378	ko00000,ko00001,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,CT_A_B,CT_C_D
k59_1734710_2	1173022.Cri9333_3571	4.74e-25	95.5	2E3TC@1|root,32YQV@2|Bacteria,1G8Z7@1117|Cyanobacteria,1HD49@1150|Oscillatoriales	1117|Cyanobacteria	S	SPTR Helix-turn-helix protein, CopG family protein	-	-	-	-	-	-	-	-	-	-	-	-	CopG_antitoxin
k59_1448547_1	1485544.JQKP01000001_gene1035	2.58e-105	313.0	COG2876@1|root,COG2876@2|Bacteria,1QVAD@1224|Proteobacteria,2VZA1@28216|Betaproteobacteria,44V5H@713636|Nitrosomonadales	28216|Betaproteobacteria	E	DAHP synthetase I family	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
k59_1320383_1	1304883.KI912532_gene3032	5.54e-74	227.0	COG4659@1|root,COG4659@2|Bacteria,1RDEP@1224|Proteobacteria,2VS39@28216|Betaproteobacteria,2KVKH@206389|Rhodocyclales	206389|Rhodocyclales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
k59_1320383_2	1304883.KI912532_gene3031	1.96e-09	57.4	COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,2VJZJ@28216|Betaproteobacteria,2KUDZ@206389|Rhodocyclales	206389|Rhodocyclales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
k59_87095_1	1249480.B649_00655	3.14e-14	76.6	COG2604@1|root,COG2604@2|Bacteria,1R4P0@1224|Proteobacteria,42NB8@68525|delta/epsilon subdivisions,2YMMI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	hmm pf01973	pseE	-	-	-	-	-	-	-	-	-	-	-	MAF_flag10
k59_729042_1	1168067.JAGP01000001_gene637	1.09e-141	405.0	COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,1RPYV@1236|Gammaproteobacteria,45ZPG@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
k59_729042_2	768486.EHR_13450	1.41e-18	85.5	COG0207@1|root,COG0262@1|root,COG0207@2|Bacteria,COG0262@2|Bacteria,1TSIR@1239|Firmicutes,4H9QS@91061|Bacilli,4AZ6X@81852|Enterococcaceae	91061|Bacilli	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046385,GO:0046483,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
k59_912544_1	387092.NIS_1751	1.56e-52	186.0	COG1283@1|root,COG1283@2|Bacteria,1MUDE@1224|Proteobacteria,42PW9@68525|delta/epsilon subdivisions,2YN4S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Na Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans
k59_1206259_1	709032.Sulku_1310	5.28e-66	216.0	COG1956@1|root,COG3604@1|root,COG1956@2|Bacteria,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,42Y69@68525|delta/epsilon subdivisions,2YNEN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	Transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF_2,HTH_8,Sigma54_activat
k59_1565936_1	1249480.B649_00355	7.36e-60	194.0	COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,42NI1@68525|delta/epsilon subdivisions,2YMHQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
k59_1565936_2	1249480.B649_00350	7.62e-39	135.0	COG0575@1|root,COG0575@2|Bacteria,1NDQ6@1224|Proteobacteria,43DJ3@68525|delta/epsilon subdivisions,2YTJ4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
k59_1233943_2	1172562.HCN_1094	2.42e-28	111.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,42NJ0@68525|delta/epsilon subdivisions,2YM9A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
k59_764027_1	1116472.MGMO_37c00170	2.46e-60	196.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,1RPI8@1236|Gammaproteobacteria,1XDWR@135618|Methylococcales	135618|Methylococcales	D	recombinase XerD	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_1527632_1	944547.ABLL_0812	1.74e-106	311.0	COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,42Z5B@68525|delta/epsilon subdivisions,2YRH6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	-	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
k59_1527632_2	944547.ABLL_0813	2.42e-142	410.0	COG0037@1|root,COG0037@2|Bacteria,1R4D0@1224|Proteobacteria,42QGB@68525|delta/epsilon subdivisions,2YT41@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	TIGRFAM N-acetyl sugar amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_470824_1	485915.Dret_0404	4.17e-65	213.0	COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,42PV5@68525|delta/epsilon subdivisions,2WIKH@28221|Deltaproteobacteria,2M9T5@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	PFAM Multi antimicrobial extrusion protein MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
k59_764047_1	159087.Daro_3649	3.94e-79	239.0	COG0664@1|root,COG0664@2|Bacteria,1R6BV@1224|Proteobacteria,2VN3A@28216|Betaproteobacteria,2KVAG@206389|Rhodocyclales	206389|Rhodocyclales	K	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	nnr	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
k59_764047_2	1304883.KI912532_gene1350	1.06e-42	145.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,2VH7N@28216|Betaproteobacteria,2KUPT@206389|Rhodocyclales	206389|Rhodocyclales	L	exodeoxyribonuclease III	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
k59_1527666_1	886293.Sinac_7402	4.19e-79	264.0	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG3850@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,COG3850@2|Bacteria,2IXFD@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg
k59_881614_1	709032.Sulku_1126	1.03e-196	587.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2YMRQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_529748_1	159087.Daro_2863	2.06e-13	68.9	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2VHM6@28216|Betaproteobacteria,2KV73@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_529748_2	1304883.KI912532_gene2053	6.73e-72	218.0	COG2142@1|root,COG2142@2|Bacteria,1MZR9@1224|Proteobacteria,2VSJN@28216|Betaproteobacteria,2KWK5@206389|Rhodocyclales	206389|Rhodocyclales	C	Succinate dehydrogenase, hydrophobic	-	-	-	ko:K00242	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
k59_764066_1	159087.Daro_3022	4.65e-49	166.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VH4C@28216|Betaproteobacteria,2KVUF@206389|Rhodocyclales	206389|Rhodocyclales	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k59_764066_2	159087.Daro_3021	1.37e-32	123.0	COG2308@1|root,COG2308@2|Bacteria,1MUAD@1224|Proteobacteria,2VI55@28216|Betaproteobacteria,2KV17@206389|Rhodocyclales	206389|Rhodocyclales	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
k59_940411_2	159087.Daro_3109	4.23e-50	161.0	2E4XG@1|root,32ZRD@2|Bacteria,1N79W@1224|Proteobacteria,2VWJP@28216|Betaproteobacteria,2KXKU@206389|Rhodocyclales	206389|Rhodocyclales	S	tryptophan synthase subunit beta	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_353173_1	159087.Daro_2188	1.33e-125	390.0	COG3523@1|root,COG3523@2|Bacteria,1MV3D@1224|Proteobacteria,2VJ0M@28216|Betaproteobacteria,2KV24@206389|Rhodocyclales	206389|Rhodocyclales	S	function. A few members resemble the ImcF protein, which has been proposed to be involved in Vibrio cholerae cell surface reorganisation that results in increased adherence to epithelial cells line and increased conjugation frequency	-	-	-	ko:K11891	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	IcmF-related,IcmF_C,ImcF-related_N
k59_1762293_1	1458275.AZ34_09965	2.57e-22	97.4	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,2VH9C@28216|Betaproteobacteria,4ABC9@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM permease YjgP YjgQ family protein	lptF	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_1762293_2	338969.Rfer_2114	1.07e-15	76.6	COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,2VHA1@28216|Betaproteobacteria,4ABSU@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM permease YjgP YjgQ family protein	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_1468487_1	29581.BW37_01416	2.58e-14	79.3	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VI4Q@28216|Betaproteobacteria,4738E@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	Belongs to the peptidase S1C family	mucD	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
k59_1703609_1	709032.Sulku_2367	3.58e-91	272.0	COG1427@1|root,COG1427@2|Bacteria,1RCS0@1224|Proteobacteria,42MJZ@68525|delta/epsilon subdivisions,2YN8T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
k59_1703613_1	522306.CAP2UW1_3770	2.19e-84	269.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,2VJ2J@28216|Betaproteobacteria,1KPU2@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	CP	Energy production and conversion Inorganic ion transport and metabolism	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
k59_236006_1	1249480.B649_09430	6.46e-67	210.0	COG0745@1|root,COG0745@2|Bacteria,1PGAE@1224|Proteobacteria,4348Y@68525|delta/epsilon subdivisions,2YREY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_1821280_1	709032.Sulku_1643	7.69e-61	203.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2YMW5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,MCPsignal,dCache_2,sCache_2
k59_1821280_2	1249480.B649_07580	1.77e-49	162.0	COG1262@1|root,COG1262@2|Bacteria,1R6GS@1224|Proteobacteria,42XMH@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Protein of unknown function (DUF1566)	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,DUF1566
k59_1529641_1	1485544.JQKP01000001_gene1202	3.87e-45	146.0	COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,2VTZ1@28216|Betaproteobacteria,44W12@713636|Nitrosomonadales	28216|Betaproteobacteria	C	4Fe-4S binding domain	fdx1	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
k59_1529641_2	580332.Slit_2365	1.85e-36	127.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,2VMQQ@28216|Betaproteobacteria,44VPS@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
k59_765440_1	1249480.B649_00410	2.79e-106	311.0	COG1961@1|root,COG1961@2|Bacteria,1Q5XK@1224|Proteobacteria,42TRW@68525|delta/epsilon subdivisions,2YQ0Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	PFAM Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_7,Resolvase
k59_649237_1	709032.Sulku_2606	5.73e-178	514.0	COG1328@1|root,COG1328@2|Bacteria,1MWMS@1224|Proteobacteria,42M8V@68525|delta/epsilon subdivisions,2YMVB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Ribonucleoside-triphosphate reductase	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
k59_295994_1	1165841.SULAR_03762	4e-21	92.8	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2YR9K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	-	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
k59_295994_2	1249480.B649_05380	1.66e-152	436.0	COG1085@1|root,COG1085@2|Bacteria,1MU3E@1224|Proteobacteria,42MP4@68525|delta/epsilon subdivisions,2YNIF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1085 Galactose-1-phosphate uridylyltransferase	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
k59_1646427_1	1121921.KB898711_gene1935	1.68e-24	107.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,1RS25@1236|Gammaproteobacteria,2PMKR@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
k59_237658_2	1442598.JABW01000002_gene1692	3.15e-27	107.0	COG1351@1|root,COG1351@2|Bacteria,1Q73I@1224|Proteobacteria,42S3A@68525|delta/epsilon subdivisions	1224|Proteobacteria	H	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
k59_824861_1	1415778.JQMM01000001_gene351	7.18e-25	108.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,1RM8M@1236|Gammaproteobacteria,1J4WW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016021,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	iEcSMS35_1347.EcSMS35_0678,iSbBS512_1146.SbBS512_E0590	CN_hydrolase
k59_1177160_1	709032.Sulku_0261	5.76e-39	142.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2YTAQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
k59_1235683_1	1537917.JU82_09790	1.96e-138	395.0	COG4976@1|root,COG4976@2|Bacteria,1R1JX@1224|Proteobacteria,43DAA@68525|delta/epsilon subdivisions,2YTHB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM)	cmoA	-	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_25
k59_1059160_1	1124983.PFLCHA0_c32480	1.06e-95	291.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RNW9@1236|Gammaproteobacteria,1YN1P@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.113	ko:K12256	ko00330,ko01100,map00330,map01100	-	R08714	RC00008,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
k59_1177162_1	159087.Daro_2902	5.55e-39	138.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,2VH1F@28216|Betaproteobacteria,2KUVS@206389|Rhodocyclales	206389|Rhodocyclales	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,Response_reg
k59_178428_1	1537917.JU82_01110	2.79e-95	279.0	COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,42RJX@68525|delta/epsilon subdivisions,2YP8Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
k59_1000925_1	1229485.AMYV01000043_gene1297	1.63e-96	298.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,1RMCN@1236|Gammaproteobacteria,1J4RN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	COG0659 Sulfate permease and related transporters (MFS superfamily)	ybaR	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k59_883345_2	709032.Sulku_2305	2.65e-79	241.0	COG1385@1|root,COG1385@2|Bacteria,1QDSD@1224|Proteobacteria,42S1W@68525|delta/epsilon subdivisions,2YP9M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
k59_1235731_1	1249480.B649_09300	3.83e-118	340.0	COG1192@1|root,COG1192@2|Bacteria,1NGVZ@1224|Proteobacteria,42VBJ@68525|delta/epsilon subdivisions	1224|Proteobacteria	D	Involved in chromosome partitioning	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	-
k59_824902_1	1537917.JU82_02085	2.38e-109	340.0	COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,1QUIU@1224|Proteobacteria,42M7I@68525|delta/epsilon subdivisions,2YMX0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG3893 inactivated superfamily I helicase	addB	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
k59_1764010_1	159087.Daro_3782	2.75e-87	265.0	COG0119@1|root,COG0119@2|Bacteria,1MVQG@1224|Proteobacteria,2VIXZ@28216|Betaproteobacteria,2KVIN@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds	-	-	4.1.3.39,4.1.3.43	ko:K18365	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R00750,R05298	RC00307,RC00371,RC00572	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	DmpG_comm,HMGL-like
k59_1764010_2	159087.Daro_3783	1.91e-126	365.0	COG4569@1|root,COG4569@2|Bacteria,1MV23@1224|Proteobacteria,2VMVU@28216|Betaproteobacteria,2KV1Q@206389|Rhodocyclales	206389|Rhodocyclales	Q	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds	-	-	1.2.1.10,1.2.1.87	ko:K18366	ko00362,ko00620,ko00621,ko00622,ko00650,ko01100,ko01120,ko01220,map00362,map00620,map00621,map00622,map00650,map01100,map01120,map01220	M00569	R00228,R01172,R09097	RC00004,RC00184,RC01195	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	AcetDehyd-dimer,Semialdhyde_dh
k59_3862_1	1165841.SULAR_03652	6.08e-70	221.0	2DKFZ@1|root,309D6@2|Bacteria,1QZK6@1224|Proteobacteria,43CQP@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Domain of unknown function (DUF4382)	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,DUF4382
k59_531857_2	1249480.B649_00595	2.36e-100	316.0	COG0715@1|root,COG0834@1|root,COG4191@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PNA@68525|delta/epsilon subdivisions,2YTBI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EPT	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,NMT1,SBP_bac_3
k59_531869_2	709032.Sulku_0724	1.85e-94	288.0	COG3608@1|root,COG3608@2|Bacteria,1Q5G3@1224|Proteobacteria,42MSH@68525|delta/epsilon subdivisions,2YMTA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	C-terminal domain of metallo-carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M99,Peptidase_M99_C
k59_1000977_1	709032.Sulku_0387	1.76e-136	395.0	29W5U@1|root,30HQY@2|Bacteria,1QUJN@1224|Proteobacteria,42NUV@68525|delta/epsilon subdivisions,2YNFP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_3895_1	709032.Sulku_0270	5.13e-137	410.0	COG1034@1|root,COG1034@2|Bacteria,1RCFT@1224|Proteobacteria,42NK4@68525|delta/epsilon subdivisions,2YNI6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G)	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4_10,Molybdopterin,NADH-G_4Fe-4S_3
k59_883391_1	709032.Sulku_0475	3.41e-58	191.0	COG1419@1|root,COG1419@2|Bacteria,1MUQW@1224|Proteobacteria,42NBF@68525|delta/epsilon subdivisions,2YN28@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar biosynthesis	flhF	-	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	SRP54
k59_883391_2	709032.Sulku_0476	6.01e-50	166.0	COG0455@1|root,COG0455@2|Bacteria,1R8IW@1224|Proteobacteria,42PF7@68525|delta/epsilon subdivisions,2YM9X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Belongs to the ParA family	flhG	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	AAA_31,ParA
k59_1529772_1	1121406.JAEX01000017_gene1914	0.00066	44.7	COG3009@1|root,COG3009@2|Bacteria,1N8BW@1224|Proteobacteria,42UW2@68525|delta/epsilon subdivisions,2WQFD@28221|Deltaproteobacteria,2M9P5@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	ABC-type transport auxiliary lipoprotein component	-	-	-	ko:K09857	-	-	-	-	ko00000	-	-	-	ABC_trans_aux
k59_1529772_2	1121406.JAEX01000017_gene1913	1.77e-34	139.0	COG1463@1|root,COG3008@1|root,COG1463@2|Bacteria,COG3008@2|Bacteria,1MU1T@1224|Proteobacteria,42PHS@68525|delta/epsilon subdivisions,2X5NU@28221|Deltaproteobacteria,2MGTM@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	MlaD protein	pqiB	-	-	ko:K06192	-	-	-	-	ko00000	-	-	-	MlaD
k59_120356_1	1165841.SULAR_03862	6.53e-38	139.0	COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,42YPF@68525|delta/epsilon subdivisions,2YRMB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Uncharacterized ACR, YdiU/UPF0061 family	-	-	-	-	-	-	-	-	-	-	-	-	UPF0061
k59_120356_2	387093.SUN_1492	5.68e-13	69.7	COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,42PHY@68525|delta/epsilon subdivisions,2YMBI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG0155 Sulfite reductase, beta subunit (hemoprotein)	-	-	1.7.7.1,1.8.7.1	ko:K00366,ko:K00392	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00531	R00790,R00859,R03600	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
k59_531901_1	709032.Sulku_0240	1.12e-11	70.1	COG0745@1|root,COG0745@2|Bacteria,1QXJT@1224|Proteobacteria,42V47@68525|delta/epsilon subdivisions,2YQ8S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	RESPONSE REGULATOR receiver	-	-	-	ko:K07288	-	-	-	-	ko00000	-	-	-	-
k59_1294369_1	1249480.B649_11170	6.07e-48	160.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,42N67@68525|delta/epsilon subdivisions,2YMDK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
k59_1411686_1	768710.DesyoDRAFT_3061	2.74e-08	59.3	COG3209@1|root,COG3209@2|Bacteria,1TR8F@1239|Firmicutes,248C6@186801|Clostridia,263Z8@186807|Peptococcaceae	186801|Clostridia	M	TIGRFAM RHS repeat-associated core domain	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,RHS_repeat
k59_61581_2	67281.JNZZ01000003_gene4224	2.16e-15	77.4	COG0726@1|root,COG0726@2|Bacteria,2HEQK@201174|Actinobacteria,4182J@629295|Streptomyces griseus group	201174|Actinobacteria	G	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
k59_120377_1	1123326.JFBL01000002_gene1687	7.16e-65	207.0	COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,42N54@68525|delta/epsilon subdivisions,2YNS5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
k59_3941_1	570952.ATVH01000019_gene771	1.02e-72	255.0	COG3170@1|root,COG3170@2|Bacteria,1Q45C@1224|Proteobacteria,2U08F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_649418_1	1537917.JU82_10620	4.14e-124	377.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,42MW3@68525|delta/epsilon subdivisions,2YMT6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
k59_61593_1	1249480.B649_01880	6.58e-49	169.0	COG2433@1|root,COG2433@2|Bacteria,1QW3W@1224|Proteobacteria,42RB0@68525|delta/epsilon subdivisions,2YNE9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Pfam Transposase IS66	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
k59_61593_2	1249480.B649_01885	6.97e-25	98.2	COG4659@1|root,COG4659@2|Bacteria,1NP43@1224|Proteobacteria,43BHC@68525|delta/epsilon subdivisions,2YQ00@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1177272_1	667014.Thein_0996	1.79e-08	54.3	COG1212@1|root,COG1212@2|Bacteria,2GGVZ@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
k59_1177272_2	1123517.JOMR01000001_gene297	7.79e-80	247.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1S2WF@1236|Gammaproteobacteria,46277@72273|Thiotrichales	72273|Thiotrichales	C	Iron-containing alcohol dehydrogenase	-	-	1.1.3.48	ko:K19714	-	-	R11394	RC03427	ko00000,ko01000,ko01005	-	-	-	Fe-ADH
k59_706943_1	1537917.JU82_04870	5.56e-58	188.0	COG0726@1|root,COG0726@2|Bacteria,1MWUE@1224|Proteobacteria,42QSJ@68525|delta/epsilon subdivisions,2YTM4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
k59_883454_1	367737.Abu_2217	2.46e-18	84.7	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,42P35@68525|delta/epsilon subdivisions,2YN2K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	iIT341.HP0867	LpxB
k59_883454_2	1249480.B649_04265	7.16e-114	327.0	2AHYJ@1|root,318BT@2|Bacteria,1Q04R@1224|Proteobacteria,42RKI@68525|delta/epsilon subdivisions,2YPAQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_883454_3	709032.Sulku_1024	2.11e-27	102.0	COG2703@1|root,COG2703@2|Bacteria,1Q3XR@1224|Proteobacteria,42XYK@68525|delta/epsilon subdivisions,2YQRN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	oxygen carrier activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_825013_1	1249480.B649_04470	1.08e-94	281.0	COG0454@1|root,COG0456@2|Bacteria,1Q5DX@1224|Proteobacteria,4313C@68525|delta/epsilon subdivisions,2YSF5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1529856_1	1249480.B649_00245	3.2e-173	500.0	COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,42NGP@68525|delta/epsilon subdivisions,2YN81@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Flagellar hook protein flgE	flgE	GO:0005575,GO:0005623,GO:0009288,GO:0009425,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flagellin_IN,Flg_bb_rod,Flg_bbr_C
k59_1294420_1	709032.Sulku_1081	4.01e-16	74.3	2A51M@1|root,30TPZ@2|Bacteria,1Q07Y@1224|Proteobacteria,42RR3@68525|delta/epsilon subdivisions,2YP94@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_532001_1	377629.TERTU_0035	1.99e-39	147.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1MWPE@1224|Proteobacteria,1RN8X@1236|Gammaproteobacteria,2PMQ1@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	JK	16S rRNA methyltransferase RsmB/F	sun	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
k59_825044_1	857087.Metme_0999	7.03e-83	273.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1RNST@1236|Gammaproteobacteria,1XGZ1@135618|Methylococcales	135618|Methylococcales	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
k59_532005_1	1304883.KI912532_gene2989	2.62e-175	498.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,2VIKN@28216|Betaproteobacteria,2KU6Y@206389|Rhodocyclales	206389|Rhodocyclales	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
k59_1529888_1	1249480.B649_02295	2.13e-101	298.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,42P2Z@68525|delta/epsilon subdivisions,2YN11@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
k59_532007_1	1249480.B649_00600	1.19e-75	239.0	COG0642@1|root,COG2205@2|Bacteria,1N9SU@1224|Proteobacteria,43BZY@68525|delta/epsilon subdivisions,2YTEZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c
k59_1059328_1	159087.Daro_1805	1.32e-13	65.9	2CC3U@1|root,2ZFR7@2|Bacteria,1P5IB@1224|Proteobacteria,2W6AZ@28216|Betaproteobacteria,2KZG3@206389|Rhodocyclales	206389|Rhodocyclales	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
k59_1059328_2	1304883.KI912532_gene2246	2.58e-42	141.0	COG0508@1|root,COG0508@2|Bacteria,1N29Y@1224|Proteobacteria,2VUWM@28216|Betaproteobacteria,2KX22@206389|Rhodocyclales	206389|Rhodocyclales	C	Biotin-requiring enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
k59_1177315_1	85643.Tmz1t_2631	3.4e-24	103.0	COG3850@1|root,COG3850@2|Bacteria,1MWZT@1224|Proteobacteria,2VIFM@28216|Betaproteobacteria,2KV4T@206389|Rhodocyclales	206389|Rhodocyclales	T	Type IV pili methyl-accepting chemotaxis transducer N-term	-	-	2.7.13.3	ko:K07673	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HAMP,HATPase_c,HisKA_3,PilJ
k59_4029_1	709032.Sulku_0119	1.98e-130	378.0	COG0739@1|root,COG0739@2|Bacteria,1MY2X@1224|Proteobacteria,42U06@68525|delta/epsilon subdivisions,2YP2U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_497264_1	1249480.B649_10610	2.85e-50	175.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2YNUU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	COG2804 Type II secretory pathway ATPase PulE Tfp pilus assembly pathway ATPase PilB	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
k59_1029619_1	1537917.JU82_02025	8.09e-56	187.0	COG0642@1|root,COG2205@2|Bacteria,1Q179@1224|Proteobacteria,4313A@68525|delta/epsilon subdivisions,2YS9S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07645	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	-
k59_1438591_1	1304883.KI912532_gene1957	1.19e-48	164.0	COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,2VHPJ@28216|Betaproteobacteria,2KV1X@206389|Rhodocyclales	206389|Rhodocyclales	G	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component	-	-	-	ko:K11688	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctP
k59_315919_1	387093.SUN_0897	3.71e-47	161.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,42NS3@68525|delta/epsilon subdivisions,2YTNJ@29547|Epsilonproteobacteria	1224|Proteobacteria	S	ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_315919_2	1165841.SULAR_00620	1.86e-50	175.0	COG4664@1|root,COG4665@1|root,COG4664@2|Bacteria,COG4665@2|Bacteria,1R4MZ@1224|Proteobacteria,42MQU@68525|delta/epsilon subdivisions,2YMC7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	TRAP transporter, DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM,DctQ
k59_791310_1	159087.Daro_0296	1.65e-101	321.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2VHCZ@28216|Betaproteobacteria,2KVY9@206389|Rhodocyclales	206389|Rhodocyclales	P	AcrB/AcrD/AcrF family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
k59_1146885_1	709032.Sulku_0482	1.93e-160	455.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,42MZR@68525|delta/epsilon subdivisions,2YN0Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
k59_791328_1	1165841.SULAR_03577	1.57e-15	72.4	COG1734@1|root,COG1734@2|Bacteria,1NH80@1224|Proteobacteria,42WPX@68525|delta/epsilon subdivisions,2YQEX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG1734 DnaK suppressor protein	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
k59_791328_2	1301098.PKB_3926	8.52e-26	106.0	COG1387@1|root,COG1387@2|Bacteria,1MYXV@1224|Proteobacteria	1224|Proteobacteria	E	Belongs to the PHP family	dpx	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
k59_907132_1	1132855.KB913035_gene531	1.03e-37	129.0	COG3093@1|root,COG3093@2|Bacteria,1NA48@1224|Proteobacteria,2VUT2@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_37
k59_376562_1	709032.Sulku_0130	2.43e-20	83.6	COG2076@1|root,COG2076@2|Bacteria,1MZ6P@1224|Proteobacteria,42TM1@68525|delta/epsilon subdivisions,2YQPI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Small Multidrug Resistance protein	-	-	-	ko:K03297,ko:K11741	-	-	-	-	ko00000,ko02000	2.A.7.1	-	-	Multi_Drug_Res
k59_376562_2	1536772.R70723_12245	6.58e-37	139.0	COG0154@1|root,COG0154@2|Bacteria,1TSAQ@1239|Firmicutes,4HDD7@91061|Bacilli,26RPR@186822|Paenibacillaceae	91061|Bacilli	J	Allophanate hydrolase	-	-	3.5.1.54	ko:K01457	ko00220,ko00791,ko01100,ko01120,map00220,map00791,map01100,map01120	-	R00005	RC02756	ko00000,ko00001,ko01000	-	-	-	Amidase
k59_1200309_1	159087.Daro_3370	1.59e-58	187.0	COG0327@1|root,COG0327@2|Bacteria,1MVUN@1224|Proteobacteria,2VIX1@28216|Betaproteobacteria,2KV29@206389|Rhodocyclales	206389|Rhodocyclales	S	NIF3 (NGG1p interacting factor 3)	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
k59_1266020_1	1249480.B649_01370	7.39e-110	327.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,42PFG@68525|delta/epsilon subdivisions,2YN2E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1252 NADH dehydrogenase FAD-containing subunit	ndh	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_1146927_1	159087.Daro_3193	1.02e-33	117.0	2EH8J@1|root,33B0E@2|Bacteria,1NEWF@1224|Proteobacteria,2VXG1@28216|Betaproteobacteria,2KX83@206389|Rhodocyclales	206389|Rhodocyclales	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	-	-	-	-	-	-	-	-	-	-	COX4_pro
k59_1146927_2	159087.Daro_3192	4.65e-80	241.0	COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,2VPW8@28216|Betaproteobacteria,2KVSD@206389|Rhodocyclales	206389|Rhodocyclales	C	Heme copper-type cytochrome quinol oxidase, subunit 3	-	-	-	ko:K02164	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	COX3
k59_1032883_1	1537917.JU82_01670	5.36e-148	453.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,43DMZ@68525|delta/epsilon subdivisions,2YMMS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_849630_1	709032.Sulku_1606	2.93e-31	121.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,42MYN@68525|delta/epsilon subdivisions,2YMXA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	molybdopterin oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin,Molydop_binding
k59_849630_2	1537917.JU82_04350	1.63e-16	79.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,42MYN@68525|delta/epsilon subdivisions,2YMXA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	molybdopterin oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin,Molydop_binding
k59_500386_1	1250278.JQNQ01000001_gene587	4e-35	137.0	COG0457@1|root,COG0642@1|root,COG0784@1|root,COG0457@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,1HYZK@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg,TPR_12,TPR_8
k59_1377295_1	1165841.SULAR_05553	3.39e-62	197.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,42MPH@68525|delta/epsilon subdivisions,2YMZ9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	N-acetylmuramoyl-L-alanine amidase	amiA	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
k59_1377295_2	827.JFJK01000016_gene209	1.96e-22	90.9	COG0221@1|root,COG0221@2|Bacteria,1RA2F@1224|Proteobacteria,42MQB@68525|delta/epsilon subdivisions,2YM8X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
k59_678934_1	985665.HPL003_23600	2.23e-34	133.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,4HAHH@91061|Bacilli,26T9D@186822|Paenibacillaceae	91061|Bacilli	M	Belongs to the peptidase S11 family	dacB	GO:0003674,GO:0003824,GO:0004175,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
k59_376608_1	387093.SUN_1021	2.74e-18	82.0	COG1191@1|root,COG1943@1|root,COG1191@2|Bacteria,COG1943@2|Bacteria,1MX0E@1224|Proteobacteria,42NN0@68525|delta/epsilon subdivisions,2YPQG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
k59_1852712_1	159087.Daro_1716	1.45e-113	348.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,2VIAU@28216|Betaproteobacteria,2KUM5@206389|Rhodocyclales	206389|Rhodocyclales	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_1032935_2	709032.Sulku_0830	5.18e-50	168.0	COG0676@1|root,COG0676@2|Bacteria,1Q7VN@1224|Proteobacteria,42SFK@68525|delta/epsilon subdivisions,2YPP5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the glucose-6-phosphate 1-epimerase family	-	-	5.1.3.15	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	-	R02739	RC00563	ko00000,ko00001,ko01000	-	-	-	Aldose_epim
k59_1852715_2	709032.Sulku_1508	2.22e-99	293.0	COG0454@1|root,COG0456@2|Bacteria,1Q9FS@1224|Proteobacteria,42YQT@68525|delta/epsilon subdivisions,2YRH5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
k59_437360_1	583345.Mmol_1322	2.03e-104	314.0	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,2VING@28216|Betaproteobacteria,2KKU1@206350|Nitrosomonadales	206350|Nitrosomonadales	O	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	Trigger_C,Trigger_N
k59_907195_2	568703.LGG_00430	1.4e-07	54.7	COG1123@1|root,COG4172@2|Bacteria,1VRD0@1239|Firmicutes,4ISFN@91061|Bacilli,3FBXM@33958|Lactobacillaceae	91061|Bacilli	P	ATP-binding cassette cobalt transporter	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran,DUF3744
k59_1441624_1	1165841.SULAR_07440	1.09e-85	264.0	COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,42MRJ@68525|delta/epsilon subdivisions,2YMF2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,UPF0004
k59_1377329_1	159087.Daro_3990	1.47e-153	475.0	COG0517@1|root,COG2203@1|root,COG3829@1|root,COG5001@1|root,COG0517@2|Bacteria,COG2203@2|Bacteria,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KUCK@206389|Rhodocyclales	206389|Rhodocyclales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CZB,EAL,GAF_2,GGDEF,PAS_4,PAS_9
k59_261694_1	1249480.B649_01210	8.88e-85	263.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2YNBN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k59_1441627_1	387093.SUN_2257	1.78e-70	224.0	COG2956@1|root,COG2956@2|Bacteria,1QUIS@1224|Proteobacteria,42M7G@68525|delta/epsilon subdivisions,2YMKN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_7,TPR_8
k59_617549_1	387093.SUN_1321	5.99e-39	139.0	29CAW@1|root,2ZZ9C@2|Bacteria,1Q5FH@1224|Proteobacteria,42Q2S@68525|delta/epsilon subdivisions,2YQ1W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_617549_2	387093.SUN_1322	2.11e-34	120.0	COG1734@1|root,COG1734@2|Bacteria,1N8RB@1224|Proteobacteria,42W5H@68525|delta/epsilon subdivisions,2YT6W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	DnaK suppressor protein	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
k59_203448_1	395494.Galf_2868	1.14e-52	186.0	COG0659@1|root,COG0664@1|root,COG0659@2|Bacteria,COG0664@2|Bacteria,1MVWV@1224|Proteobacteria,2VN25@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp,cNMP_binding
k59_1670959_2	709032.Sulku_0125	4.64e-49	162.0	COG0600@1|root,COG0600@2|Bacteria,1MWDJ@1224|Proteobacteria,42PJ5@68525|delta/epsilon subdivisions,2YNPV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
k59_562097_2	563040.Saut_0925	4.39e-11	63.9	2C5PA@1|root,34CE7@2|Bacteria,1Q66Q@1224|Proteobacteria,42XE8@68525|delta/epsilon subdivisions	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1085074_1	1249480.B649_05600	6.75e-74	236.0	COG0791@1|root,COG0791@2|Bacteria,1R45H@1224|Proteobacteria,42NS0@68525|delta/epsilon subdivisions,2YN06@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,N_NLPC_P60,Peptidase_M15_4,SH3_6,SH3_7
k59_1611532_1	1122604.JONR01000009_gene2397	2.92e-19	88.6	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,1RN9J@1236|Gammaproteobacteria,1X3AX@135614|Xanthomonadales	135614|Xanthomonadales	M	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_1314911_1	1196029.ALIM01000020_gene5076	2.72e-95	294.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4HAV1@91061|Bacilli,1ZE8P@1386|Bacillus	91061|Bacilli	EH	Belongs to the TPP enzyme family	alsS	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_1670974_2	1537917.JU82_02000	4.15e-73	224.0	COG0546@1|root,COG0546@2|Bacteria,1RBMZ@1224|Proteobacteria,42RG3@68525|delta/epsilon subdivisions,2YP44@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Hydrolase	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_203475_1	944547.ABLL_1067	2.3e-12	65.5	COG2731@1|root,COG2731@2|Bacteria,1MZ1I@1224|Proteobacteria,42W5J@68525|delta/epsilon subdivisions,2YQBP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Domain of unknown function (DUF386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF386
k59_203475_2	1367491.BN865_07140	1.7e-43	147.0	COG0546@1|root,COG0546@2|Bacteria,1N0R4@1224|Proteobacteria,42UH8@68525|delta/epsilon subdivisions,2YPXT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
k59_1032990_2	1537917.JU82_00865	2.18e-124	355.0	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,42QTS@68525|delta/epsilon subdivisions,2YTQW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EH	Anthranilate synthase	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
k59_1559195_1	555778.Hneap_2027	1e-181	531.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,1WWC8@135613|Chromatiales	135613|Chromatiales	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_679004_1	159087.Daro_3776	1.17e-105	316.0	2C4IG@1|root,2Z8A1@2|Bacteria,1QTHZ@1224|Proteobacteria,2VN98@28216|Betaproteobacteria,2KVXJ@206389|Rhodocyclales	206389|Rhodocyclales	S	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1329
k59_679004_2	159087.Daro_3777	6.86e-19	85.5	28J5I@1|root,2Z91C@2|Bacteria,1QVI2@1224|Proteobacteria,2VN9N@28216|Betaproteobacteria,2KV6Q@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF1302)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1302
k59_617615_1	1234364.AMSF01000072_gene1795	6.83e-07	55.5	29Y2F@1|root,30JVD@2|Bacteria,1RAWX@1224|Proteobacteria,1S4VP@1236|Gammaproteobacteria,1X6T6@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1085120_1	1244531.CIG1485E_0063	4.15e-84	260.0	COG0438@1|root,COG0438@2|Bacteria,1MY5T@1224|Proteobacteria,42NYR@68525|delta/epsilon subdivisions,2YNJT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
k59_1085126_1	1249480.B649_00375	3.02e-48	161.0	2A50M@1|root,30TNT@2|Bacteria,1PDM4@1224|Proteobacteria,42QJ6@68525|delta/epsilon subdivisions,2YPYD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	AMIN domain	-	-	-	-	-	-	-	-	-	-	-	-	AMIN
k59_203540_1	1249480.B649_11085	5.48e-102	322.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,42NKH@68525|delta/epsilon subdivisions,2YMVS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the helicase family. UvrD subfamily	addA	-	3.1.11.5	ko:K03582	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C
k59_969920_1	1304883.KI912532_gene3170	1.14e-69	234.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1144@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1144@2|Bacteria,1MVM0@1224|Proteobacteria,2VN9C@28216|Betaproteobacteria,2M00F@206389|Rhodocyclales	206389|Rhodocyclales	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
k59_1559322_1	709032.Sulku_1435	3.49e-105	320.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,42N50@68525|delta/epsilon subdivisions,2YN1V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
k59_1852892_1	583345.Mmol_1484	2.18e-24	107.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,2VJXV@28216|Betaproteobacteria,2KNV2@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	HlyD_D23
k59_791659_1	1537917.JU82_03530	1.95e-120	357.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,42MV4@68525|delta/epsilon subdivisions,2YN13@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
k59_791659_2	204536.SULAZ_0730	2.75e-73	247.0	COG3696@1|root,COG3696@2|Bacteria	2|Bacteria	P	silver ion transport	czcA	-	-	ko:K07787,ko:K15726	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.2,2.A.6.1.4	-	-	ACR_tran
k59_725076_1	709032.Sulku_1615	1.37e-106	316.0	COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,1MXYZ@1224|Proteobacteria,42M4E@68525|delta/epsilon subdivisions,2YMY0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF1722)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
k59_316139_1	944547.ABLL_1446	1.35e-117	357.0	COG4772@1|root,COG4772@2|Bacteria,1MUIH@1224|Proteobacteria	1224|Proteobacteria	P	Receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_849829_1	1249480.B649_10090	7.72e-123	356.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,42NEW@68525|delta/epsilon subdivisions,2YME1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	heptosyltransferase ii	waaF	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
k59_147872_1	572480.Arnit_2323	9.96e-24	101.0	COG2986@1|root,COG2986@2|Bacteria,1MU6K@1224|Proteobacteria,42MST@68525|delta/epsilon subdivisions,2YNF3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Aromatic amino acid lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
k59_147872_2	929558.SMGD1_1389	4.21e-52	175.0	COG0463@1|root,COG0463@2|Bacteria,1QTWH@1224|Proteobacteria,43D0B@68525|delta/epsilon subdivisions,2YP1X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_316141_1	709032.Sulku_2057	9.31e-85	273.0	COG1251@1|root,COG1740@1|root,COG1251@2|Bacteria,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,42PSD@68525|delta/epsilon subdivisions,2YNBA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	hydrogenase (NiFe) small subunit HydA	-	-	1.12.5.1	ko:K05927	-	-	-	-	ko00000,ko01000	-	-	-	Fer2_BFD,NiFe_hyd_SSU_C,Oxidored_q6,Pyr_redox_2
k59_1441865_3	62928.azo3482	8.08e-21	93.2	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1MW3N@1224|Proteobacteria,2VJG2@28216|Betaproteobacteria,2KU82@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_907403_1	709032.Sulku_0913	1.3e-58	199.0	COG3920@1|root,COG3920@2|Bacteria,1MVPJ@1224|Proteobacteria,42PDP@68525|delta/epsilon subdivisions,2YMI8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	two-component sensor histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HisKA_2
k59_1729687_2	159087.Daro_2728	1.07e-57	194.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,2KV7D@206389|Rhodocyclales	206389|Rhodocyclales	NT	Cache_2	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,dCache_2,sCache_2
k59_1671159_1	765912.Thimo_0558	5.97e-91	271.0	COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,1RN1J@1236|Gammaproteobacteria,1WWMS@135613|Chromatiales	135613|Chromatiales	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
k59_1266353_1	1304883.KI912532_gene2077	1.04e-135	414.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KV5K@206389|Rhodocyclales	206389|Rhodocyclales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,dCache_1
k59_907435_1	1165841.SULAR_02698	4.39e-71	234.0	COG4907@1|root,COG4907@2|Bacteria,1MXPY@1224|Proteobacteria,42MA5@68525|delta/epsilon subdivisions,2YRC9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
k59_907435_2	1165841.SULAR_02693	7.81e-49	160.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,42S15@68525|delta/epsilon subdivisions,2YT6B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
k59_376829_1	1537917.JU82_02915	2.9e-103	300.0	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,42SNY@68525|delta/epsilon subdivisions,2YNVI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
k59_1671197_1	159087.Daro_0726	2.61e-42	157.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VI5B@28216|Betaproteobacteria,2KVAE@206389|Rhodocyclales	206389|Rhodocyclales	NT	Signal transducing histidine kinase, homodimeric domain	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
k59_1441950_1	709032.Sulku_0240	5.62e-47	164.0	COG0745@1|root,COG0745@2|Bacteria,1QXJT@1224|Proteobacteria,42V47@68525|delta/epsilon subdivisions,2YQ8S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	RESPONSE REGULATOR receiver	-	-	-	ko:K07288	-	-	-	-	ko00000	-	-	-	-
k59_1611782_1	1165841.SULAR_07745	9.4e-90	269.0	COG0704@1|root,COG0704@2|Bacteria,1Q5TJ@1224|Proteobacteria,42STN@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	Phosphate uptake regulator	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
k59_1611782_2	1165841.SULAR_07740	4.2e-118	342.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42PA1@68525|delta/epsilon subdivisions,2YNMR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_970176_2	1216932.CM240_1666	2.9e-48	169.0	COG1086@1|root,COG1086@2|Bacteria,1U3RH@1239|Firmicutes,24K9I@186801|Clostridia,36KEF@31979|Clostridiaceae	186801|Clostridia	GM	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
k59_1732439_1	1144342.PMI40_01853	8.22e-14	73.6	COG2199@1|root,COG3706@2|Bacteria,1QUY1@1224|Proteobacteria,2VM8G@28216|Betaproteobacteria,472MM@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_1790590_1	292415.Tbd_0917	1.82e-08	52.4	COG2010@1|root,COG2010@2|Bacteria,1N91W@1224|Proteobacteria,2WC94@28216|Betaproteobacteria,1KT9N@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K17223	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	Cytochrome_CBB3
k59_1790590_2	1123392.AQWL01000004_gene2732	6.89e-61	192.0	COG5501@1|root,COG5501@2|Bacteria,1RH4J@1224|Proteobacteria,2VT8I@28216|Betaproteobacteria,1KT0V@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Sulfur oxidation protein SoxY	-	-	-	ko:K17226	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxY
k59_910222_1	123214.PERMA_1839	4e-42	156.0	COG3303@1|root,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
k59_1088239_1	1537917.JU82_02695	1.73e-108	321.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,42MFM@68525|delta/epsilon subdivisions,2YMJU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
k59_1790606_1	709032.Sulku_2193	5.97e-35	125.0	2C2VD@1|root,338G0@2|Bacteria,1P3HX@1224|Proteobacteria,42NM6@68525|delta/epsilon subdivisions,2YM9Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_937090_2	62977.ACIAD3591	1.73e-26	104.0	COG0765@1|root,COG0765@2|Bacteria,1MVB6@1224|Proteobacteria,1RPGH@1236|Gammaproteobacteria,3NSMR@468|Moraxellaceae	1236|Gammaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	yecS_3	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
k59_228825_1	709032.Sulku_0131	9.21e-76	244.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,42PK7@68525|delta/epsilon subdivisions,2YMS5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Amidase	-	-	3.5.1.54	ko:K01457	ko00220,ko00791,ko01100,ko01120,map00220,map00791,map01100,map01120	-	R00005	RC02756	ko00000,ko00001,ko01000	-	-	-	Amidase
k59_1524463_1	1537917.JU82_02980	6.49e-97	295.0	COG0642@1|root,COG2205@2|Bacteria,1QUJ7@1224|Proteobacteria,43BJF@68525|delta/epsilon subdivisions,2YNM7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,sCache_like
k59_1701514_1	318161.Sden_3315	8.27e-38	140.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RMS9@1236|Gammaproteobacteria,2Q9A7@267890|Shewanellaceae	1236|Gammaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_1701514_2	517417.Cpar_0461	5.33e-47	163.0	COG1432@1|root,COG3170@1|root,COG1432@2|Bacteria,COG3170@2|Bacteria,1FECY@1090|Chlorobi	1090|Chlorobi	NU	OST-HTH/LOTUS domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
k59_407155_1	1132855.KB913035_gene442	2.02e-31	129.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KNJ1@206350|Nitrosomonadales	206350|Nitrosomonadales	T	PFAM EAL domain protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_4,PAS_9
k59_1816252_1	159087.Daro_3941	2.22e-53	172.0	COG2413@1|root,COG2413@2|Bacteria,1RFTH@1224|Proteobacteria,2VJC9@28216|Betaproteobacteria,2KUIR@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_292035_1	159087.Daro_0377	1.12e-50	169.0	COG3396@1|root,COG3396@2|Bacteria,1MVQ7@1224|Proteobacteria,2VHQZ@28216|Betaproteobacteria,2KUW7@206389|Rhodocyclales	206389|Rhodocyclales	S	Phenylacetate-CoA oxygenase subunit PaaA	paaA	-	1.14.13.149	ko:K02609	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
k59_292035_2	1123255.JHYS01000007_gene1673	1.04e-154	442.0	COG0683@1|root,COG0683@2|Bacteria,1MXR4@1224|Proteobacteria,2VHP9@28216|Betaproteobacteria,4ACT4@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_468838_1	1249480.B649_05100	1.93e-43	154.0	COG4773@1|root,COG4773@2|Bacteria,1QZMX@1224|Proteobacteria,42SA0@68525|delta/epsilon subdivisions,2YPCD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_233213_1	452662.SJA_C1-12670	1.45e-08	55.1	COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,2TQUS@28211|Alphaproteobacteria,2K1QA@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
k59_468861_1	929713.NIASO_18010	8.51e-25	107.0	COG0210@1|root,COG0210@2|Bacteria,4NDWN@976|Bacteroidetes,1IP3C@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_468895_2	944546.ABED_1645	2.1e-67	216.0	COG1216@1|root,COG1216@2|Bacteria,1NM61@1224|Proteobacteria,42TSF@68525|delta/epsilon subdivisions,2YQUW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_407232_1	1249480.B649_02295	1.37e-81	246.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,42P2Z@68525|delta/epsilon subdivisions,2YN11@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
k59_407262_1	1249480.B649_11085	5.64e-103	323.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,42NKH@68525|delta/epsilon subdivisions,2YMVS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the helicase family. UvrD subfamily	addA	-	3.1.11.5	ko:K03582	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C
k59_753108_1	159087.Daro_2729	5.35e-87	257.0	COG0314@1|root,COG0314@2|Bacteria,1RGUX@1224|Proteobacteria,2VRMG@28216|Betaproteobacteria,2KW54@206389|Rhodocyclales	206389|Rhodocyclales	H	Molybdopterin converting factor, large subunit	moaE	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
k59_233309_1	211586.SO_2089	1.19e-13	66.6	COG0375@1|root,COG0375@2|Bacteria,1MZJH@1224|Proteobacteria,1SXX2@1236|Gammaproteobacteria,2QCNN@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
k59_233309_2	94122.Shewana3_1868	2.67e-42	148.0	COG0309@1|root,COG0309@2|Bacteria,1MVCC@1224|Proteobacteria,1RQBE@1236|Gammaproteobacteria,2Q9FV@267890|Shewanellaceae	1236|Gammaproteobacteria	O	AIR synthase related protein domain protein	hypE	GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0018193,GO:0018198,GO:0018249,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046892,GO:0051604,GO:0071704,GO:1901564	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
k59_1524595_1	395494.Galf_0548	1.71e-70	217.0	COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,2VHDK@28216|Betaproteobacteria,44VJR@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
k59_753147_1	688245.CtCNB1_1400	4.94e-22	89.7	COG3123@1|root,COG3123@2|Bacteria,1MZ8N@1224|Proteobacteria,2VSCI@28216|Betaproteobacteria,4AEFW@80864|Comamonadaceae	28216|Betaproteobacteria	S	Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions	ppnP	-	2.4.2.1,2.4.2.2	ko:K09913	ko00230,ko00240,map00230,map00240	-	R01561,R01570,R01863,R01876,R02147,R02296,R02297	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	DUF1255
k59_753147_2	387093.SUN_2397	1.21e-65	205.0	2AN57@1|root,31D31@2|Bacteria,1QA4U@1224|Proteobacteria,42WXP@68525|delta/epsilon subdivisions,2YR18@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_233345_1	709032.Sulku_0532	2.11e-104	305.0	COG2231@1|root,COG2231@2|Bacteria,1RDJ8@1224|Proteobacteria,42QYA@68525|delta/epsilon subdivisions,2YP2S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	endonuclease III	magIII	-	-	ko:K07457	-	-	-	-	ko00000	-	-	-	HhH-GPD
k59_233345_2	709032.Sulku_0531	5.31e-34	123.0	COG1692@1|root,COG1692@2|Bacteria,1MW12@1224|Proteobacteria,42PCG@68525|delta/epsilon subdivisions,2YN6X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	metallophosphoesterase	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
k59_1701710_1	596154.Alide2_0716	1.5e-43	150.0	COG1073@1|root,COG1073@2|Bacteria,1RA0U@1224|Proteobacteria,2VQ78@28216|Betaproteobacteria,4ACM1@80864|Comamonadaceae	28216|Betaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
k59_1701710_2	159087.Daro_2433	2.67e-26	99.4	COG0236@1|root,COG0236@2|Bacteria,1N83X@1224|Proteobacteria,2VW0V@28216|Betaproteobacteria,2KXFZ@206389|Rhodocyclales	206389|Rhodocyclales	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
k59_1231853_1	377629.TERTU_1237	7.67e-31	121.0	COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,1RN0Y@1236|Gammaproteobacteria,2PP63@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	N	Bacterial flagellin C-terminal helical region	fliC	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_IN,Flagellin_N
k59_1231853_2	317025.Tcr_1453	4.29e-66	212.0	COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,1RN0Y@1236|Gammaproteobacteria,4625R@72273|Thiotrichales	72273|Thiotrichales	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	-	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
k59_469032_1	717772.THIAE_03650	3.42e-72	221.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,1S3UP@1236|Gammaproteobacteria,460KM@72273|Thiotrichales	72273|Thiotrichales	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
k59_877745_1	1537917.JU82_11765	4.98e-90	271.0	COG0598@1|root,COG0598@2|Bacteria,1NWUN@1224|Proteobacteria,42S8K@68525|delta/epsilon subdivisions,2YPDR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	CorA-like Mg2 transporter protein	-	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
k59_233389_1	1249480.B649_01175	7.84e-289	810.0	COG1034@1|root,COG1034@2|Bacteria,1RCFT@1224|Proteobacteria,42NK4@68525|delta/epsilon subdivisions,2YNI6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G)	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4,Fer4_7,NADH-G_4Fe-4S_3
k59_1348433_1	159087.Daro_0846	5.35e-119	345.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,2VIQ4@28216|Betaproteobacteria,2KUG2@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
k59_1348433_2	159087.Daro_0847	1.43e-60	196.0	COG3317@1|root,COG3317@2|Bacteria,1N670@1224|Proteobacteria,2VHS5@28216|Betaproteobacteria,2KUM7@206389|Rhodocyclales	206389|Rhodocyclales	M	(Lipo)protein	nlpB	-	-	ko:K07287	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	Lipoprotein_18
k59_1231931_1	709032.Sulku_0516	1.84e-114	343.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,42M6V@68525|delta/epsilon subdivisions,2YM9I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k59_110001_1	159087.Daro_3211	4.7e-34	131.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,2VJIC@28216|Betaproteobacteria,2KU79@206389|Rhodocyclales	206389|Rhodocyclales	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
k59_469134_1	709032.Sulku_1657	1.09e-110	330.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,430C9@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	TIGRFAM Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Hemerythrin,NIT,PilJ
k59_1348490_1	1165841.SULAR_00620	7.74e-87	274.0	COG4664@1|root,COG4665@1|root,COG4664@2|Bacteria,COG4665@2|Bacteria,1R4MZ@1224|Proteobacteria,42MQU@68525|delta/epsilon subdivisions,2YMC7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	TRAP transporter, DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM,DctQ
k59_1524707_1	159087.Daro_3012	1.22e-19	82.0	COG1598@1|root,COG1598@2|Bacteria	2|Bacteria	N	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_753297_1	159087.Daro_0852	3.54e-122	352.0	COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,2VKZV@28216|Betaproteobacteria,2KVW9@206389|Rhodocyclales	206389|Rhodocyclales	S	Inhibitor of apoptosis-promoting Bax1	-	-	-	ko:K19416	-	M00742	-	-	ko00000,ko00002,ko02000	1.A.14.2.1	-	-	Bax1-I
k59_1348506_1	709032.Sulku_0260	8.71e-173	493.0	COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,42N9J@68525|delta/epsilon subdivisions,2YMC3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Long-chain fatty acid transport protein	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k59_1232002_1	1249480.B649_06370	6.2e-72	227.0	COG1261@1|root,COG1261@2|Bacteria,1Q3ZV@1224|Proteobacteria,42Y1K@68525|delta/epsilon subdivisions,2YQRI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Chaperone for flagella basal body P-ring formation	flgA	-	-	ko:K02386	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	ChapFlgA
k59_1232015_1	709032.Sulku_1633	2.75e-90	278.0	COG2206@1|root,COG2206@2|Bacteria,1R53C@1224|Proteobacteria,42R7P@68525|delta/epsilon subdivisions,2YPRS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
k59_1232015_2	1537917.JU82_04275	0.000435	40.0	COG2257@1|root,COG2257@2|Bacteria,1N7F1@1224|Proteobacteria,42VB5@68525|delta/epsilon subdivisions,2YPVJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	of the cytoplasmic domain of flagellar protein FhlB	flhB2	-	-	ko:K04061	-	-	-	-	ko00000,ko02044	-	-	-	Bac_export_2
k59_1232039_1	159087.Daro_0820	8.26e-147	429.0	COG0515@1|root,COG0631@1|root,COG0515@2|Bacteria,COG0631@2|Bacteria,1MV1P@1224|Proteobacteria,2VH5K@28216|Betaproteobacteria,2KY31@206389|Rhodocyclales	206389|Rhodocyclales	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PP2C_2,Pkinase
k59_1701899_2	709032.Sulku_0584	5.74e-136	395.0	COG2861@1|root,COG2861@2|Bacteria,1N3JP@1224|Proteobacteria,42RJN@68525|delta/epsilon subdivisions,2YP6V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Divergent polysaccharide deacetylase	-	-	-	ko:K09798	-	-	-	-	ko00000	-	-	-	Polysacc_deac_2
k59_753375_1	1249480.B649_07685	1.6e-103	322.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2YMAI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k59_1348573_1	640081.Dsui_2935	1.77e-107	320.0	COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,2VJZN@28216|Betaproteobacteria,2KVAK@206389|Rhodocyclales	206389|Rhodocyclales	C	NAD(P) transhydrogenase, alpha subunit	pntAA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
k59_1348573_2	666681.M301_0432	2.19e-10	59.7	COG0526@1|root,COG0526@2|Bacteria,1MZ5J@1224|Proteobacteria,2VSFR@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Redoxin
k59_233565_1	1304883.KI912532_gene651	3.02e-61	193.0	COG1999@1|root,COG1999@2|Bacteria,1RHJ8@1224|Proteobacteria,2VS84@28216|Betaproteobacteria,2KYVD@206389|Rhodocyclales	206389|Rhodocyclales	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
k59_1524784_1	709032.Sulku_0291	1.06e-56	182.0	2AK46@1|root,31AU1@2|Bacteria,1Q64N@1224|Proteobacteria,432DV@68525|delta/epsilon subdivisions,2YSQ8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_877933_1	159087.Daro_0756	3.21e-73	230.0	COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,2VJAZ@28216|Betaproteobacteria,2KV45@206389|Rhodocyclales	206389|Rhodocyclales	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgI	-	-	ko:K02394	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgI
k59_1524800_1	1249480.B649_02930	2.53e-46	159.0	COG2861@1|root,COG2861@2|Bacteria,1N3JP@1224|Proteobacteria,42RJN@68525|delta/epsilon subdivisions,2YP6V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Divergent polysaccharide deacetylase	-	-	-	ko:K09798	-	-	-	-	ko00000	-	-	-	Polysacc_deac_2
k59_1701982_1	709032.Sulku_2251	1.19e-251	703.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,42M1T@68525|delta/epsilon subdivisions,2YMJ5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Cell division protein FtsI penicillin-binding protein	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
k59_1524819_1	1249480.B649_01575	6.38e-125	360.0	COG0390@1|root,COG0390@2|Bacteria,1MV2N@1224|Proteobacteria,42UN8@68525|delta/epsilon subdivisions,2YQ92@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Uncharacterised protein family (UPF0014)	-	-	-	ko:K02069	-	M00211	-	-	ko00000,ko00002,ko02000	9.B.25.1	-	-	UPF0014
k59_753490_2	1537917.JU82_06450	3.72e-143	406.0	COG1191@1|root,COG1191@2|Bacteria,1MWEU@1224|Proteobacteria,42QQ8@68525|delta/epsilon subdivisions,2YMJ7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Belongs to the sigma-70 factor family	fliA	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
k59_1702026_1	1165841.SULAR_02348	2.47e-90	271.0	COG1121@1|root,COG1121@2|Bacteria,1MUDW@1224|Proteobacteria,42NI8@68525|delta/epsilon subdivisions,2YMKV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	ABC transporter	fecE	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
k59_110241_2	1249480.B649_04190	8.49e-79	242.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,42NCJ@68525|delta/epsilon subdivisions,2YMQJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
k59_347041_1	929558.SMGD1_0414	5.44e-42	153.0	COG1944@1|root,COG1944@2|Bacteria,1MV7K@1224|Proteobacteria,42M8K@68525|delta/epsilon subdivisions,2YMZN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	YcaO cyclodehydratase, ATP-ad Mg2+-binding	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	YcaO
k59_1702102_1	709032.Sulku_2228	3.97e-170	499.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,42M70@68525|delta/epsilon subdivisions,2YMJM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_1524914_1	338969.Rfer_1694	7.37e-77	248.0	COG2521@1|root,COG2521@2|Bacteria,1QZ6R@1224|Proteobacteria	1224|Proteobacteria	S	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_753578_1	666681.M301_2131	5e-129	370.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,2VI6B@28216|Betaproteobacteria,2KKH4@206350|Nitrosomonadales	206350|Nitrosomonadales	T	PFAM response regulator receiver	-	-	-	ko:K07659	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_292473_1	709032.Sulku_1182	2.16e-29	120.0	COG0840@1|root,COG0840@2|Bacteria,1R486@1224|Proteobacteria,42Q5Y@68525|delta/epsilon subdivisions,2YNT8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	CZB,MCPsignal
k59_469553_2	1249480.B649_06470	1.67e-05	44.7	COG2033@1|root,COG2033@2|Bacteria,1NDWH@1224|Proteobacteria,42RSM@68525|delta/epsilon subdivisions,2YP5S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Desulfoferrodoxin ferrous iron-binding	-	-	1.15.1.2	ko:K05919	-	-	-	-	ko00000,ko01000	-	-	-	Desulfoferrodox
k59_878138_1	387093.SUN_0589	1.61e-47	163.0	COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,42P0U@68525|delta/epsilon subdivisions,2YNIG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	AI-2E family transporter	-	-	-	ko:K11744	-	-	-	-	ko00000	-	-	-	AI-2E_transport
k59_878138_2	1165841.SULAR_04497	2.69e-19	83.2	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,42M8E@68525|delta/epsilon subdivisions,2YNXC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iIT341.HP0618	ADK
k59_878150_1	1249480.B649_01440	2.16e-75	226.0	COG2199@1|root,COG3706@2|Bacteria,1QUJM@1224|Proteobacteria,42TUI@68525|delta/epsilon subdivisions,2YPSC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Response regulator receiver	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg
k59_878150_2	1537917.JU82_03795	3.6e-45	162.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2YMJS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,NIT,Response_reg
k59_1232402_1	1304883.KI912532_gene742	5.3e-118	349.0	COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,2VHR0@28216|Betaproteobacteria,2KUNT@206389|Rhodocyclales	206389|Rhodocyclales	T	Domain of unknown function (DUF3391)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3391,HD_5
k59_1232420_1	1227457.C451_05630	1.24e-11	68.6	arCOG09146@1|root,arCOG09146@2157|Archaea,2XVE2@28890|Euryarchaeota,23UK9@183963|Halobacteria	183963|Halobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1
k59_469633_1	709032.Sulku_0086	8.6e-42	142.0	COG0760@1|root,COG0760@2|Bacteria	2|Bacteria	O	peptidyl-prolyl cis-trans isomerase activity	surA	-	5.2.1.8	ko:K03769,ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,SurA_N,SurA_N_2,SurA_N_3
k59_1585012_1	709032.Sulku_0396	1.15e-59	191.0	2DBB6@1|root,2Z85M@2|Bacteria,1QMDX@1224|Proteobacteria,42QTF@68525|delta/epsilon subdivisions,2YP1H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1585012_2	1537917.JU82_05240	1.89e-31	120.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2YMB5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	abc transporter atp-binding protein	yheS	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
k59_1819837_1	709032.Sulku_0786	1.55e-98	310.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,42MKB@68525|delta/epsilon subdivisions,2YMIZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
k59_176124_1	1537917.JU82_06500	2.12e-188	532.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,42MJ7@68525|delta/epsilon subdivisions,2YMWU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	COG0402 Cytosine deaminase and related metal-dependent	orf1	-	3.5.4.40	ko:K20810	ko00130,ko01110,map00130,map01110	-	R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k59_1350224_1	555778.Hneap_2386	1.16e-93	284.0	COG0738@1|root,COG0738@2|Bacteria	2|Bacteria	G	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
k59_1819862_1	159087.Daro_0020	5.15e-98	295.0	COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,2VIZJ@28216|Betaproteobacteria,2KUKQ@206389|Rhodocyclales	206389|Rhodocyclales	S	protein containing LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
k59_1408928_1	1537917.JU82_11785	6.76e-137	393.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,42MU5@68525|delta/epsilon subdivisions,2YM85@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_N
k59_998015_1	1165841.SULAR_07585	1.55e-68	230.0	COG1034@1|root,COG1034@2|Bacteria,1RCFT@1224|Proteobacteria,42NK4@68525|delta/epsilon subdivisions,2YNI6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G)	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4,Fer4_7,NADH-G_4Fe-4S_3
k59_880608_1	1537917.JU82_07385	1.03e-69	224.0	COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,42MQ6@68525|delta/epsilon subdivisions,2YNPN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DNA photolyase family	phrB	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
k59_1408932_1	561231.Pecwa_2245	2.96e-104	316.0	COG2719@1|root,COG2719@2|Bacteria,1MW6U@1224|Proteobacteria,1RPU2@1236|Gammaproteobacteria,1MSCX@122277|Pectobacterium	1236|Gammaproteobacteria	S	SpoVR like protein	ycgB	GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716	-	ko:K06415	-	-	-	-	ko00000	-	-	-	SpoVR
k59_1722918_1	641107.CDLVIII_3037	8.63e-39	135.0	COG0693@1|root,COG0693@2|Bacteria,1V7V7@1239|Firmicutes,24IC8@186801|Clostridia,36VZI@31979|Clostridiaceae	186801|Clostridia	S	PFAM ThiJ PfpI	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
k59_1844565_1	1502770.JQMG01000001_gene500	1.61e-62	208.0	COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,2VRIT@28216|Betaproteobacteria,2KKJQ@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Putative 2OG-Fe(II) oxygenase	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_5,TPR_1,TPR_2,TPR_8
k59_720113_1	1249480.B649_05570	8.04e-53	174.0	COG1058@1|root,COG1058@2|Bacteria,1MVG6@1224|Proteobacteria,42R50@68525|delta/epsilon subdivisions,2YNX5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
k59_1605272_2	387093.SUN_1014	2.58e-63	198.0	COG2267@1|root,COG2267@2|Bacteria,1Q0VR@1224|Proteobacteria,42SJB@68525|delta/epsilon subdivisions,2YPM4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1194147_1	1132855.KB913035_gene1042	8.08e-118	347.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,2VJJ1@28216|Betaproteobacteria,2KMA3@206350|Nitrosomonadales	206350|Nitrosomonadales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
k59_609103_1	944547.ABLL_1601	1.15e-30	130.0	COG5001@1|root,COG5001@2|Bacteria,1R4H0@1224|Proteobacteria,43CII@68525|delta/epsilon subdivisions,2YTD5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_1194150_1	1537917.JU82_01805	9.93e-145	414.0	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,42MIX@68525|delta/epsilon subdivisions,2YM93@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
k59_1023937_1	1249480.B649_11090	1.78e-134	404.0	COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,1QUIU@1224|Proteobacteria,42M7I@68525|delta/epsilon subdivisions,2YMX0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG3893 inactivated superfamily I helicase	addB	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
k59_1370803_1	595494.Tola_0479	1.19e-51	185.0	COG3829@1|root,COG5001@1|root,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1Y3ZA@135624|Aeromonadales	135624|Aeromonadales	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_9
k59_1844613_1	1165841.SULAR_07720	1.21e-124	358.0	COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,42MIP@68525|delta/epsilon subdivisions,2YMPW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
k59_1844613_2	1165841.SULAR_07715	1.39e-63	197.0	COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,42SIR@68525|delta/epsilon subdivisions,2YP9V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
k59_670858_1	1123255.JHYS01000012_gene1332	1.78e-45	167.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,4A9QK@80864|Comamonadaceae	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_9,Response_reg
k59_1257951_1	1537917.JU82_04280	2.16e-153	453.0	2AN97@1|root,32J0R@2|Bacteria,1PCA3@1224|Proteobacteria,42T7U@68525|delta/epsilon subdivisions,2YPPF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Flg_hook
k59_1257952_1	709032.Sulku_2200	4.91e-65	219.0	COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,42M8J@68525|delta/epsilon subdivisions,2YNGB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member	recD	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2,Viral_helicase1
k59_670876_2	1121035.AUCH01000022_gene3213	9.89e-17	79.7	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,2VHP4@28216|Betaproteobacteria,2KUSH@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
k59_19946_1	1123367.C666_06205	5.53e-73	236.0	COG1270@1|root,COG1270@2|Bacteria,1MURM@1224|Proteobacteria,2VIDF@28216|Betaproteobacteria,2KUAV@206389|Rhodocyclales	206389|Rhodocyclales	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	-	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
k59_1257957_1	1249480.B649_11305	1.33e-108	329.0	COG3278@1|root,COG3278@2|Bacteria,1QAUQ@1224|Proteobacteria,42P3Q@68525|delta/epsilon subdivisions,2YNBX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the heme-copper respiratory oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	COX1
k59_1722983_1	1537917.JU82_01790	1.5e-68	212.0	2AJZN@1|root,31ANZ@2|Bacteria,1Q5WH@1224|Proteobacteria,42UJ4@68525|delta/epsilon subdivisions,2YPXB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1433326_1	312153.Pnuc_0320	4.92e-65	224.0	COG0500@1|root,COG3754@1|root,COG4372@1|root,COG2226@2|Bacteria,COG3754@2|Bacteria,COG4372@2|Bacteria,1QU2J@1224|Proteobacteria,2WH47@28216|Betaproteobacteria,1K57C@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Rhamnan synthesis protein F	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_WbsX,RgpF
k59_370837_1	247490.KSU1_C0413	3.54e-23	104.0	COG5001@1|root,COG5001@2|Bacteria	2|Bacteria	T	cyclic-guanylate-specific phosphodiesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,MASE1,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_370837_2	760154.Sulba_1124	5.19e-05	45.4	COG0177@1|root,COG0177@2|Bacteria,1RAK3@1224|Proteobacteria,42M4V@68525|delta/epsilon subdivisions,2YNKT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	tigr02757	-	-	-	-	-	-	-	-	-	-	-	-	DUF2400
k59_1433331_1	296591.Bpro_3991	1.3e-59	197.0	COG2227@1|root,COG2227@2|Bacteria,1QU62@1224|Proteobacteria,2VJ8J@28216|Betaproteobacteria,4ACZ9@80864|Comamonadaceae	28216|Betaproteobacteria	H	Putative zinc binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_13,Methyltransf_14,Methyltransf_23
k59_311320_2	1249480.B649_08050	1.32e-48	157.0	2BSRI@1|root,32MUE@2|Bacteria,1Q3E8@1224|Proteobacteria,42X6B@68525|delta/epsilon subdivisions,2YQST@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_311320_3	709032.Sulku_0806	4.27e-65	210.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2YMTZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iIT341.HP0623	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_1370852_1	762376.AXYL_02879	2.79e-133	397.0	COG0028@1|root,COG0028@2|Bacteria,1MWUB@1224|Proteobacteria,2VMC1@28216|Betaproteobacteria,3T5NB@506|Alcaligenaceae	28216|Betaproteobacteria	EH	Belongs to the TPP enzyme family	xsc	-	2.3.3.15	ko:K03852	ko00430,map00430	-	R05651	RC02903,RC02909	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_1844685_1	1366050.N234_32490	2.1e-33	120.0	COG5616@1|root,COG5616@2|Bacteria,1N092@1224|Proteobacteria,2VT5Y@28216|Betaproteobacteria,1K5VA@119060|Burkholderiaceae	28216|Betaproteobacteria	S	cAMP biosynthetic process	ragC	-	-	ko:K21008	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	LpoB
k59_1844685_2	269799.Gmet_1967	2.55e-21	95.9	COG2203@1|root,COG2203@2|Bacteria,1PB4M@1224|Proteobacteria,42XVQ@68525|delta/epsilon subdivisions,2WWYG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PelD GGDEF domain	-	-	-	ko:K21009	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	PelD_GGDEF
k59_1723004_1	929558.SMGD1_2866	2.78e-47	167.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1RGCV@1224|Proteobacteria,43CEF@68525|delta/epsilon subdivisions,2YTC1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_1723004_2	1537917.JU82_11440	1.2e-50	162.0	2AJ62@1|root,319QQ@2|Bacteria,1Q3M5@1224|Proteobacteria,42XHG@68525|delta/epsilon subdivisions,2YQWM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1433365_1	1249480.B649_10985	2.09e-84	253.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,42QT1@68525|delta/epsilon subdivisions,2YNYN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	riboflavin synthase alpha	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
k59_1433365_2	1537917.JU82_01935	1.27e-31	113.0	2A14F@1|root,30PAA@2|Bacteria,1Q6CF@1224|Proteobacteria,432V8@68525|delta/epsilon subdivisions,2YSWU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_141123_1	243365.CV_3165	1.13e-35	138.0	COG5267@1|root,COG5267@2|Bacteria,1MWJK@1224|Proteobacteria,2VIYI@28216|Betaproteobacteria,2KSJR@206351|Neisseriales	206351|Neisseriales	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
k59_553882_1	582744.Msip34_1551	7.58e-90	272.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,2VH2M@28216|Betaproteobacteria,2KMFH@206350|Nitrosomonadales	206350|Nitrosomonadales	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
k59_430962_1	580332.Slit_0926	1.02e-32	117.0	297UU@1|root,2ZV1D@2|Bacteria,1MXFE@1224|Proteobacteria,2VIEE@28216|Betaproteobacteria,44WA8@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1488915_1	1249480.B649_01930	1.11e-113	346.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1RGCV@1224|Proteobacteria,43CEF@68525|delta/epsilon subdivisions,2YTC1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_901306_1	709032.Sulku_2174	9.31e-140	403.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,42MGU@68525|delta/epsilon subdivisions,2YMB7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
k59_901306_2	709032.Sulku_2175	4.94e-58	188.0	COG2957@1|root,COG2957@2|Bacteria,1MX65@1224|Proteobacteria,42NAS@68525|delta/epsilon subdivisions,2YN3V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the agmatine deiminase family	aguA	-	-	-	-	-	-	-	-	-	-	-	PAD_porph
k59_1024085_1	1121374.KB891585_gene1883	2.01e-20	94.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1RPR0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	VP1483	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_4
k59_1078547_1	159087.Daro_0870	2.98e-76	238.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,2VHV3@28216|Betaproteobacteria,2KUYW@206389|Rhodocyclales	206389|Rhodocyclales	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_961652_1	572480.Arnit_2546	4.13e-63	211.0	COG1132@1|root,COG1132@2|Bacteria,1MVJD@1224|Proteobacteria,42PP5@68525|delta/epsilon subdivisions,2YN5G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	ABC transporter ATP-binding	pglK	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0006810,GO:0006869,GO:0008150,GO:0008152,GO:0008643,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015772,GO:0015920,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0022804,GO:0022857,GO:0022884,GO:0033036,GO:0034040,GO:0034645,GO:0036211,GO:0042623,GO:0042626,GO:0043170,GO:0043412,GO:0043413,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0051179,GO:0051234,GO:0055085,GO:0070085,GO:0071702,GO:0071704,GO:1901135,GO:1901137,GO:1901264,GO:1901505,GO:1901564,GO:1901566,GO:1901576	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k59_1370922_1	1132855.KB913035_gene836	8.32e-85	257.0	2E2GR@1|root,32XKS@2|Bacteria,1N41X@1224|Proteobacteria,2VUN3@28216|Betaproteobacteria,2KKWG@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
k59_1605412_1	1249480.B649_02615	7.52e-103	308.0	COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,42ME9@68525|delta/epsilon subdivisions	1224|Proteobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	trmA	-	2.1.1.189,2.1.1.190,2.1.1.35	ko:K00557,ko:K03212,ko:K03215	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	TRAM,tRNA_U5-meth_tr
k59_609244_1	159087.Daro_2022	7.53e-93	274.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2VHR2@28216|Betaproteobacteria,2KUG9@206389|Rhodocyclales	206389|Rhodocyclales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_609244_2	159087.Daro_2021	8.9e-215	603.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,2VHA7@28216|Betaproteobacteria,2KUYZ@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_783191_1	338969.Rfer_3201	2.12e-85	260.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2VKGA@28216|Betaproteobacteria,4ABF7@80864|Comamonadaceae	28216|Betaproteobacteria	V	PFAM ABC transporter related	nosF	-	-	ko:K01990,ko:K19340	ko02010,map02010	M00254,M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.132.2	-	-	ABC_tran
k59_553951_1	1123487.KB892835_gene3330	3.73e-16	76.3	COG1177@1|root,COG1177@2|Bacteria,1MUQD@1224|Proteobacteria,2VJ92@28216|Betaproteobacteria,2KVVP@206389|Rhodocyclales	206389|Rhodocyclales	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02053	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
k59_553951_2	1123487.KB892835_gene3329	5.51e-91	278.0	COG1176@1|root,COG1176@2|Bacteria,1MU1Y@1224|Proteobacteria,2VK8I@28216|Betaproteobacteria,2KUGN@206389|Rhodocyclales	206389|Rhodocyclales	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02054	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
k59_901332_1	709032.Sulku_0332	2.13e-35	128.0	COG1587@1|root,COG1587@2|Bacteria,1NMTP@1224|Proteobacteria,42T0U@68525|delta/epsilon subdivisions,2YPN4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Uroporphyrinogen-III synthase	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
k59_255709_1	1249480.B649_04350	1.59e-79	264.0	COG3829@1|root,COG5001@1|root,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YMHP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_9
k59_20026_3	1537917.JU82_04370	1.39e-26	98.6	COG2104@1|root,COG2104@2|Bacteria,1NG8E@1224|Proteobacteria,42WUA@68525|delta/epsilon subdivisions,2YQSD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	thiamine biosynthesis protein ThiS	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
k59_844459_1	511.JT27_07150	2.45e-57	201.0	COG0604@1|root,COG3321@1|root,COG0604@2|Bacteria,COG3321@2|Bacteria,1R89Z@1224|Proteobacteria,2WGJ6@28216|Betaproteobacteria	28216|Betaproteobacteria	CQ	polyketide synthase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N,Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_23,PP-binding,PS-DH,ketoacyl-synt
k59_1605432_1	443143.GM18_2847	1.13e-49	188.0	COG3614@1|root,COG3852@1|root,COG3614@2|Bacteria,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_1665006_1	395493.BegalDRAFT_2934	2.27e-90	292.0	COG0045@1|root,COG0454@1|root,COG1042@1|root,COG0045@2|Bacteria,COG0456@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,1RPXX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Acyl-CoA synthetase (NDP forming)	-	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
k59_311399_2	1537917.JU82_07195	6.31e-75	235.0	COG1362@1|root,COG1362@2|Bacteria,1NT1D@1224|Proteobacteria,42MN0@68525|delta/epsilon subdivisions,2YRFV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	M18 family aminopeptidase	-	-	3.4.11.21	ko:K01267	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	Peptidase_M18
k59_1781609_1	1348657.M622_18255	2.64e-102	332.0	COG1201@1|root,COG1205@1|root,COG1201@2|Bacteria,COG1205@2|Bacteria,1MVGH@1224|Proteobacteria,2VPE3@28216|Betaproteobacteria,2KWWK@206389|Rhodocyclales	206389|Rhodocyclales	L	helicase superfamily c-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,DUF1998,Helicase_C
k59_258191_2	709032.Sulku_2357	5.65e-225	624.0	COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,42MBH@68525|delta/epsilon subdivisions,2YN1J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
k59_1554420_2	1101195.Meth11DRAFT_0457	1.72e-30	115.0	2DNXC@1|root,32ZN4@2|Bacteria,1NKWP@1224|Proteobacteria,2VX7B@28216|Betaproteobacteria,2KN5D@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1081297_1	1280666.ATVS01000005_gene2432	1.07e-32	130.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,248Z9@186801|Clostridia,4BW52@830|Butyrivibrio	186801|Clostridia	EH	Thiamine pyrophosphate enzyme, central domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_1261331_1	640081.Dsui_2075	2.98e-82	254.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,2VJNS@28216|Betaproteobacteria,2KU7F@206389|Rhodocyclales	206389|Rhodocyclales	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
k59_786461_1	525898.Sdel_2104	1.95e-21	101.0	COG4258@1|root,COG4258@2|Bacteria,1QAEM@1224|Proteobacteria,42Q08@68525|delta/epsilon subdivisions,2YN7J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_612487_1	1121129.KB903360_gene3054	8.87e-34	126.0	COG0195@1|root,COG0195@2|Bacteria,4NFGA@976|Bacteroidetes,2FNJF@200643|Bacteroidia,22WBR@171551|Porphyromonadaceae	976|Bacteroidetes	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
k59_612487_2	1168034.FH5T_05035	3.66e-40	137.0	COG0779@1|root,COG0779@2|Bacteria,4NQ32@976|Bacteroidetes,2FUC5@200643|Bacteroidia	976|Bacteroidetes	S	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
k59_1142320_1	387093.SUN_1761	6.55e-105	309.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,42P7F@68525|delta/epsilon subdivisions,2YNFY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
k59_1142320_2	1165841.SULAR_05658	3.59e-66	205.0	COG1376@1|root,COG1376@2|Bacteria,1PPWD@1224|Proteobacteria,42ZXP@68525|delta/epsilon subdivisions,2YRVS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
k59_1436813_1	1007105.PT7_1835	2.61e-35	132.0	COG4235@1|root,COG4235@2|Bacteria,1MY4J@1224|Proteobacteria,2VQ05@28216|Betaproteobacteria,3T48N@506|Alcaligenaceae	28216|Betaproteobacteria	O	cytochrome c biogenesis	nrfG	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	TPR_16,TPR_2
k59_1196782_1	459495.SPLC1_S270840	2.52e-68	234.0	COG0457@1|root,COG1215@1|root,COG1216@1|root,COG0457@2|Bacteria,COG1215@2|Bacteria,COG1216@2|Bacteria,1GQBE@1117|Cyanobacteria,1H7DT@1150|Oscillatoriales	1117|Cyanobacteria	M	glycosyl transferase family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2,RgpF,TPR_1,TPR_11,TPR_16,TPR_2,TPR_7,TPR_8
k59_1554459_1	1249480.B649_01870	6.02e-81	251.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42NHE@68525|delta/epsilon subdivisions,2YMQ8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
k59_144261_1	709032.Sulku_2370	2.16e-104	323.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42P9M@68525|delta/epsilon subdivisions,2YNH7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CZB,HAMP,MCPsignal,dCache_3
k59_1725488_1	983917.RGE_00170	7.41e-20	89.4	COG0583@1|root,COG0583@2|Bacteria,1MV06@1224|Proteobacteria,2VHGD@28216|Betaproteobacteria,1KNCM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_1848051_2	709032.Sulku_1128	3.14e-42	144.0	COG0483@1|root,COG0483@2|Bacteria,1Q17W@1224|Proteobacteria,42T1U@68525|delta/epsilon subdivisions,2YPGV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Inositol monophosphatase	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
k59_1667476_1	1123514.KB905899_gene1338	4.49e-111	335.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,45ZW3@72273|Thiotrichales	72273|Thiotrichales	M	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
k59_1142371_1	395494.Galf_0595	7.08e-107	320.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,2VHQM@28216|Betaproteobacteria,44V1C@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
k59_313328_2	1121878.AUGL01000006_gene669	1.78e-23	102.0	COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,1RP5M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Multidrug efflux pump	mdtK	GO:0000302,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006855,GO:0006857,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0015238,GO:0015833,GO:0015893,GO:0016020,GO:0022857,GO:0033554,GO:0034599,GO:0034614,GO:0035442,GO:0035672,GO:0035673,GO:0042221,GO:0042493,GO:0042886,GO:0042887,GO:0042891,GO:0042895,GO:0042938,GO:0044464,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071702,GO:0071705,GO:0071916,GO:0071944,GO:1901700,GO:1901701,GO:1904680	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
k59_22040_1	1304883.KI912532_gene3030	3.05e-135	398.0	COG4656@1|root,COG4656@2|Bacteria,1PJVF@1224|Proteobacteria,2VM4P@28216|Betaproteobacteria,2KUV4@206389|Rhodocyclales	206389|Rhodocyclales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,Fer4_17,RnfC_N,SLBB
k59_903775_1	1537917.JU82_04965	1.84e-59	191.0	COG1076@1|root,COG1076@2|Bacteria,1N270@1224|Proteobacteria,42STV@68525|delta/epsilon subdivisions,2YPJ5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	DnaJ domain protein	-	-	-	ko:K05801	-	-	-	-	ko00000,ko03110	-	-	-	DnaJ,TerB
k59_22041_1	709032.Sulku_2224	2.84e-86	265.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,42MM1@68525|delta/epsilon subdivisions,2YN3A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	8-amino-7-oxononanoate synthase	bioF	-	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_495820_2	709032.Sulku_2008	1.19e-188	534.0	COG0446@1|root,COG0446@2|Bacteria,1QA17@1224|Proteobacteria,42P5E@68525|delta/epsilon subdivisions,2YN01@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Fad-dependent pyridine nucleotide-disulfide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_1633787_1	701176.VIBRN418_00966	5.09e-05	45.4	COG1215@1|root,COG1215@2|Bacteria,1R6YR@1224|Proteobacteria,1RRS4@1236|Gammaproteobacteria,1XTEQ@135623|Vibrionales	135623|Vibrionales	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
k59_1633787_2	1278307.KB907006_gene222	1.15e-39	145.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	-	-	-	ko:K02841,ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
k59_100563_1	929558.SMGD1_0540	4.5e-23	98.2	COG1070@1|root,COG1070@2|Bacteria,1MWS5@1224|Proteobacteria,43CSA@68525|delta/epsilon subdivisions,2YTM7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.189	ko:K11216	ko02024,map02024	-	R11183	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
k59_583802_2	1165841.SULAR_07500	1.21e-70	228.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,42MTY@68525|delta/epsilon subdivisions,2YMHI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
k59_1690756_1	1168067.JAGP01000001_gene1710	1.32e-88	284.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,1RP14@1236|Gammaproteobacteria,4609P@72273|Thiotrichales	72273|Thiotrichales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
k59_1690757_1	1249480.B649_00180	7.9e-23	97.1	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,42M81@68525|delta/epsilon subdivisions,2YMTF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_1690757_2	1249480.B649_00175	5.66e-115	336.0	COG0679@1|root,COG0679@2|Bacteria,1N5NC@1224|Proteobacteria,42PYE@68525|delta/epsilon subdivisions,2YMUI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM Auxin Efflux Carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
k59_168593_2	1307759.JOMJ01000004_gene2885	4.32e-09	59.3	COG1528@1|root,COG1528@2|Bacteria,1R9ZC@1224|Proteobacteria,42S74@68525|delta/epsilon subdivisions,2WNFJ@28221|Deltaproteobacteria,2MBEX@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Iron-storage protein	ftn	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
k59_930712_1	1537917.JU82_11155	3.74e-52	170.0	2BTHZ@1|root,32NQF@2|Bacteria,1Q3WY@1224|Proteobacteria,42XXM@68525|delta/epsilon subdivisions,2YQUG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1397918_1	159087.Daro_0219	4.96e-47	157.0	COG0640@1|root,COG0640@2|Bacteria,1RBZC@1224|Proteobacteria,2VR13@28216|Betaproteobacteria,2KW3M@206389|Rhodocyclales	206389|Rhodocyclales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1397918_2	159087.Daro_0220	8.52e-25	102.0	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,2VH54@28216|Betaproteobacteria,2KVQ1@206389|Rhodocyclales	206389|Rhodocyclales	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3
k59_396422_1	1304883.KI912532_gene564	4.56e-129	380.0	COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,2VIJ8@28216|Betaproteobacteria,2KVRS@206389|Rhodocyclales	206389|Rhodocyclales	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
k59_993840_1	1304883.KI912532_gene1525	2.65e-102	312.0	COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,2VMHK@28216|Betaproteobacteria,2KVVG@206389|Rhodocyclales	206389|Rhodocyclales	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
k59_1690816_1	1165841.SULAR_02583	6.73e-106	322.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,42MQD@68525|delta/epsilon subdivisions,2YNHI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0659 Sulfate permease and related	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k59_1873923_1	56110.Oscil6304_2567	1.1e-09	64.3	COG0517@1|root,COG2202@1|root,COG2203@1|root,COG3920@1|root,COG0517@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3920@2|Bacteria,1GHCI@1117|Cyanobacteria,1HHSY@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,HATPase_c,HisKA,HisKA_2,PAS_3,PAS_4,PAS_9,Response_reg
k59_168622_1	1429851.X548_11550	4.01e-40	145.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,1RMVW@1236|Gammaproteobacteria,1X4NT@135614|Xanthomonadales	135614|Xanthomonadales	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_814235_1	159087.Daro_0730	4.97e-68	214.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,2VKFS@28216|Betaproteobacteria,2KVRQ@206389|Rhodocyclales	206389|Rhodocyclales	H	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
k59_814235_2	1116472.MGMO_33c00020	4.08e-08	56.6	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XFYW@135618|Methylococcales	135618|Methylococcales	NT	PFAM Chemotaxis methyl-accepting receptor, signalling	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,CZB,HAMP,MCPsignal
k59_168638_1	1163617.SCD_n00973	1.53e-19	92.8	COG0484@1|root,COG0484@2|Bacteria,1Q629@1224|Proteobacteria,2VJ8G@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
k59_638910_1	709032.Sulku_0629	7.19e-129	393.0	COG1289@1|root,COG1289@2|Bacteria,1MX9H@1224|Proteobacteria,43F33@68525|delta/epsilon subdivisions,2YRBI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Aromatic acid exporter family member 1	-	-	-	-	-	-	-	-	-	-	-	-	FUSC
k59_1287732_2	214092.YPO1590	6.79e-38	141.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMDS@1236|Gammaproteobacteria,41F3S@629|Yersinia	1236|Gammaproteobacteria	J	Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs	rne	GO:0000287,GO:0000966,GO:0000967,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008312,GO:0008995,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0017151,GO:0019222,GO:0019439,GO:0019899,GO:0022607,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034655,GO:0034660,GO:0042254,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043462,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0046872,GO:0048519,GO:0050789,GO:0050790,GO:0051095,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051336,GO:0060255,GO:0065003,GO:0065007,GO:0065009,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902280	3.1.26.12	ko:K08300	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	PNPase_C,RNase_E_G,S1
k59_930779_2	522306.CAP2UW1_2537	1.12e-05	45.1	COG3197@1|root,COG3197@2|Bacteria,1NG90@1224|Proteobacteria,2VWG5@28216|Betaproteobacteria,1KR5I@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	P	Cytochrome oxidase maturation protein cbb3-type	ccoS	-	-	-	-	-	-	-	-	-	-	-	FixS
k59_1221422_1	1178825.ALIH01000004_gene2911	1.95e-105	329.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,1HY80@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
k59_1633916_1	159087.Daro_0262	2.23e-144	413.0	COG0679@1|root,COG0679@2|Bacteria,1N1X9@1224|Proteobacteria,2VIM5@28216|Betaproteobacteria,2KW61@206389|Rhodocyclales	206389|Rhodocyclales	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
k59_814252_1	767434.Fraau_2884	7.82e-09	62.0	COG0079@1|root,COG0079@2|Bacteria,1R774@1224|Proteobacteria,1SYBU@1236|Gammaproteobacteria,1X4G3@135614|Xanthomonadales	135614|Xanthomonadales	E	aminotransferase	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_744857_2	709032.Sulku_0580	1.66e-72	230.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,42M6T@68525|delta/epsilon subdivisions,2YMJD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
k59_459363_1	1165841.SULAR_04943	3.33e-55	183.0	COG0472@1|root,COG0472@2|Bacteria,1MWYW@1224|Proteobacteria,42QFA@68525|delta/epsilon subdivisions,2YTPJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
k59_704187_2	1370120.AUWR01000034_gene1956	2.8e-39	136.0	COG1848@1|root,COG1848@2|Bacteria,2IPRK@201174|Actinobacteria,23DQN@1762|Mycobacteriaceae	201174|Actinobacteria	S	PIN domain	-	GO:0005575,GO:0005576	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
k59_704188_2	159087.Daro_3722	1.22e-58	185.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,2VRD3@28216|Betaproteobacteria,2KWFM@206389|Rhodocyclales	206389|Rhodocyclales	L	methyltransferase	-	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
k59_744873_1	1249480.B649_09420	4.32e-177	501.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,42MMF@68525|delta/epsilon subdivisions,2YMPB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Glycerol-3-phosphate dehydrogenase	glpC	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_17,Fer4_7,Fer4_8
k59_284409_1	1537917.JU82_04980	1.04e-09	58.5	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,42N4K@68525|delta/epsilon subdivisions,2YMXB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
k59_284409_2	529818.AMSG_07499T0	0.000776	48.5	COG0500@1|root,KOG1331@2759|Eukaryota	2759|Eukaryota	Q	tRNA (uracil) methyltransferase activity	KIAA1456	GO:0000049,GO:0001300,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006417,GO:0006448,GO:0006725,GO:0006807,GO:0007568,GO:0007569,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008198,GO:0008270,GO:0009451,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016070,GO:0016300,GO:0016491,GO:0016705,GO:0016706,GO:0016740,GO:0016741,GO:0019222,GO:0030488,GO:0031323,GO:0031326,GO:0032259,GO:0032268,GO:0032502,GO:0034248,GO:0034470,GO:0034641,GO:0034660,GO:0035690,GO:0042221,GO:0042493,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051213,GO:0051246,GO:0051716,GO:0055114,GO:0060255,GO:0065007,GO:0070887,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:2000112	2.1.1.229	ko:K10770,ko:K15444	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_11
k59_869245_1	709032.Sulku_0089	2.73e-88	271.0	COG3174@1|root,COG3174@2|Bacteria,1NDBI@1224|Proteobacteria,42QBM@68525|delta/epsilon subdivisions,2YNPT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	MgtC family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
k59_1584828_1	1165841.SULAR_06638	6.75e-64	201.0	COG0681@1|root,COG0681@2|Bacteria,1QENE@1224|Proteobacteria,42ZRJ@68525|delta/epsilon subdivisions,2YRPB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Peptidase S24-like	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
k59_586132_1	929558.SMGD1_1187	4.16e-58	187.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,42M98@68525|delta/epsilon subdivisions,2YSZC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve
k59_1339826_1	709032.Sulku_1462	1.47e-116	345.0	COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,43BJP@68525|delta/epsilon subdivisions,2YTA6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
k59_1584856_1	159087.Daro_1290	2.35e-41	148.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,2VJ8C@28216|Betaproteobacteria,2KVHU@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.1.5,6.3.5.1	ko:K01916,ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00189,R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
k59_1584856_2	522306.CAP2UW1_2301	1.54e-62	192.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2VSEZ@28216|Betaproteobacteria,1KQQP@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	K	Nitrogen regulatory protein P-II	-	-	-	ko:K04751,ko:K04752	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
k59_1584856_3	159087.Daro_1292	3.45e-58	186.0	COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,2VQ2S@28216|Betaproteobacteria,2KWD8@206389|Rhodocyclales	206389|Rhodocyclales	S	Smr protein MutS2	-	-	-	-	-	-	-	-	-	-	-	-	Smr
k59_1636185_1	1265507.KB899636_gene2229	4.89e-27	113.0	COG0352@1|root,COG0352@2|Bacteria,1QTW3@1224|Proteobacteria,1T1YB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3,2.7.1.49,2.7.4.7	ko:K00788,ko:K14153	ko00730,ko01100,map00730,map01100	M00127	R03223,R03471,R04509,R10712	RC00002,RC00017,RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin,TMP-TENI
k59_459454_2	709032.Sulku_0697	7.88e-46	149.0	COG3951@1|root,COG3951@2|Bacteria,1Q5W9@1224|Proteobacteria,42UQG@68525|delta/epsilon subdivisions,2YPWJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MNO	Rod binding protein	flgJ	-	-	-	-	-	-	-	-	-	-	-	Rod-binding
k59_459454_3	1249480.B649_03455	6.03e-29	104.0	2AK6X@1|root,31AX3@2|Bacteria,1Q6DV@1224|Proteobacteria,432YY@68525|delta/epsilon subdivisions,2YSIQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Anti-sigma-28 factor, FlgM	-	-	-	-	-	-	-	-	-	-	-	-	FlgM
k59_459454_4	929558.SMGD1_1933	1.22e-32	118.0	2AIM0@1|root,32I9V@2|Bacteria,1Q1S6@1224|Proteobacteria,42U9Z@68525|delta/epsilon subdivisions,2YPXP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_45980_1	709032.Sulku_1433	3.42e-108	323.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,42M5C@68525|delta/epsilon subdivisions,2YM7M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	lytic murein transglycosylase	mltD	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
k59_1171872_1	1249480.B649_05265	2.95e-113	332.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,42N7U@68525|delta/epsilon subdivisions,2YN72@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	PFAM Radical SAM domain protein	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Radical_SAM
k59_337373_1	709032.Sulku_2198	7.73e-106	326.0	COG0715@1|root,COG0834@1|root,COG2199@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42UTN@68525|delta/epsilon subdivisions,2YTHQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EPT	NMT1/THI5 like	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	GGDEF,NMT1,SBP_bac_3
k59_1753705_1	1537917.JU82_01525	2.52e-38	132.0	COG2249@1|root,COG2249@2|Bacteria,1MWV9@1224|Proteobacteria,42NNM@68525|delta/epsilon subdivisions,2YNA5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	modulator of drug activity	mdaB	-	-	ko:K03923	-	-	-	-	ko00000	-	-	-	Flavodoxin_2
k59_1584919_2	75379.Tint_0622	1.89e-40	152.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,1KJ1H@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	mdtB	-	-	ko:K03296,ko:K07788,ko:K07789	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	2.A.6.2	-	-	ACR_tran
k59_399007_2	706587.Desti_1808	2.59e-18	84.7	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2WJ1T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.1.3.1,6.2.1.3	ko:K01897,ko:K22319	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	iAF987.Gmet_2229	AMP-binding,AMP-binding_C
k59_1876227_1	1479237.JMLY01000001_gene2075	1.34e-50	173.0	COG0025@1|root,COG0025@2|Bacteria,1QRKS@1224|Proteobacteria,1RRSS@1236|Gammaproteobacteria,465MA@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Sodium/hydrogen exchanger family	sod22	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
k59_1753712_2	1537917.JU82_03415	6.14e-243	674.0	COG0446@1|root,COG0446@2|Bacteria,1PWV7@1224|Proteobacteria,42QCM@68525|delta/epsilon subdivisions,2YND4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COGs COG1252 NADH dehydrogenase FAD-containing subunit	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_1876228_1	159087.Daro_3990	2.08e-74	250.0	COG0517@1|root,COG2203@1|root,COG3829@1|root,COG5001@1|root,COG0517@2|Bacteria,COG2203@2|Bacteria,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KUCK@206389|Rhodocyclales	206389|Rhodocyclales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CZB,EAL,GAF_2,GGDEF,PAS_4,PAS_9
k59_1753719_1	1249480.B649_01445	1.15e-141	432.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2YMJS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,NIT,Response_reg
k59_1339919_1	159087.Daro_3344	6.17e-26	103.0	COG0845@1|root,COG0845@2|Bacteria,1NQZ0@1224|Proteobacteria,2VJAC@28216|Betaproteobacteria,2KUKR@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
k59_1809249_1	1537917.JU82_00830	2.54e-121	356.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,42MMF@68525|delta/epsilon subdivisions,2YMPB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Glycerol-3-phosphate dehydrogenase	glpC	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_17,Fer4_7,Fer4_8
k59_816543_1	1249480.B649_01935	1.22e-65	208.0	COG0745@1|root,COG0745@2|Bacteria,1QUJR@1224|Proteobacteria,42NQS@68525|delta/epsilon subdivisions,2YN0F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_704355_2	1537917.JU82_02905	1.58e-46	154.0	COG0746@1|root,COG0746@2|Bacteria,1NEIC@1224|Proteobacteria,42SCE@68525|delta/epsilon subdivisions,2YPMS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
k59_641048_1	387093.SUN_1614	8.26e-09	54.3	COG2862@1|root,COG2862@2|Bacteria,1RFUX@1224|Proteobacteria,42T0B@68525|delta/epsilon subdivisions,2YP5M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	UPF0114
k59_641048_2	1165841.SULAR_05123	2.84e-115	338.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,42MDM@68525|delta/epsilon subdivisions,2YMIV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k59_399075_1	395493.BegalDRAFT_0775	6.62e-117	347.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,1RMV1@1236|Gammaproteobacteria,4607E@72273|Thiotrichales	72273|Thiotrichales	E	PFAM aminotransferase class-III	argD	-	2.6.1.11,2.6.1.13,2.6.1.17	ko:K00819,ko:K00821	ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00667,R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_704381_1	1304883.KI912532_gene2928	2.11e-67	229.0	COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,2VIMP@28216|Betaproteobacteria,2KV97@206389|Rhodocyclales	206389|Rhodocyclales	NU	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_8
k59_933622_1	1300005.R9RG79_9CAUD	4.2e-81	256.0	4QEFX@10239|Viruses,4QYYG@35237|dsDNA viruses  no RNA stage,4QRRV@28883|Caudovirales,4QNTK@10744|Podoviridae	10744|Podoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1809296_1	1249480.B649_03265	1.03e-70	233.0	COG2199@1|root,COG2199@2|Bacteria,1QTZT@1224|Proteobacteria,43E8E@68525|delta/epsilon subdivisions,2YN2B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_522286_1	159087.Daro_1318	1.03e-103	314.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,2VHWM@28216|Betaproteobacteria,2KUAK@206389|Rhodocyclales	206389|Rhodocyclales	P	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components	oppC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
k59_933654_1	287.DR97_2951	7.74e-38	140.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,1RMNP@1236|Gammaproteobacteria,1YDYY@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	GO:0003674,GO:0003824,GO:0003887,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0022616,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
k59_586335_1	709032.Sulku_1316	1.61e-109	326.0	COG0426@1|root,COG0426@2|Bacteria,1NDXY@1224|Proteobacteria,42N11@68525|delta/epsilon subdivisions,2YNA0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Metallo-beta-lactamase superfamily	-	-	1.6.3.4	ko:K22405	-	-	-	-	ko00000,ko01000	-	-	-	Flavodoxin_1,Lactamase_B
k59_1465800_1	709032.Sulku_0099	5.15e-36	122.0	2AJ3H@1|root,319MX@2|Bacteria,1Q39A@1224|Proteobacteria,42WZA@68525|delta/epsilon subdivisions,2YQQE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
k59_1465800_2	709032.Sulku_0100	1.22e-45	151.0	COG0421@1|root,COG0421@2|Bacteria,1PD55@1224|Proteobacteria,42UAB@68525|delta/epsilon subdivisions,2YPTY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synt_N,Spermine_synth
k59_1753794_1	159087.Daro_0955	2.45e-147	438.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,2VJYV@28216|Betaproteobacteria,2KVHX@206389|Rhodocyclales	206389|Rhodocyclales	C	COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G)	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
k59_1172033_1	159087.Daro_0624	8.96e-86	256.0	COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,2VQNZ@28216|Betaproteobacteria,2KUPA@206389|Rhodocyclales	206389|Rhodocyclales	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
k59_586367_1	582744.Msip34_1972	1.41e-70	229.0	COG1463@1|root,COG3008@1|root,COG1463@2|Bacteria,COG3008@2|Bacteria,1MU1T@1224|Proteobacteria,2VJ44@28216|Betaproteobacteria,2KKG1@206350|Nitrosomonadales	206350|Nitrosomonadales	Q	MlaD protein	-	-	-	ko:K06192	-	-	-	-	ko00000	-	-	-	MlaD
k59_1753801_1	709032.Sulku_0121	1.16e-107	340.0	COG5001@1|root,COG5001@2|Bacteria,1R4H0@1224|Proteobacteria,43CII@68525|delta/epsilon subdivisions,2YTD5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_1289912_1	1249480.B649_07400	1.8e-153	443.0	COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,42MCZ@68525|delta/epsilon subdivisions,2YNV4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	HlyD membrane-fusion protein of T1SS	-	-	-	ko:K12542	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	3.A.1.109.4,8.A.1	-	-	HlyD_3
k59_1517472_1	1123367.C666_11470	2.82e-30	118.0	COG1032@1|root,COG1032@2|Bacteria,1PK5W@1224|Proteobacteria,2VJIN@28216|Betaproteobacteria,2KVTD@206389|Rhodocyclales	206389|Rhodocyclales	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
k59_1517472_2	441620.Mpop_1756	1.03e-28	111.0	COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,2TTPH@28211|Alphaproteobacteria,1JRED@119045|Methylobacteriaceae	28211|Alphaproteobacteria	Q	PFAM Dienelactone hydrolase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
k59_745075_1	1537917.JU82_11685	8.72e-96	296.0	COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,42N42@68525|delta/epsilon subdivisions,2YMNR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
k59_996116_1	1304883.KI912532_gene1624	8.05e-26	98.6	COG4628@1|root,COG4628@2|Bacteria,1N7DG@1224|Proteobacteria	1224|Proteobacteria	S	Conserved Protein	-	-	-	-	-	-	-	-	-	-	-	-	VF530
k59_459708_1	1165841.SULAR_04417	1.2e-105	323.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,42M1S@68525|delta/epsilon subdivisions,2YMEF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	penicillin-binding protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
k59_1172148_2	1524880.A0A076G7R3_9VIRU	4.13e-35	127.0	4QAUS@10239|Viruses	10239|Viruses	S	flavin adenine dinucleotide binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_954381_2	565045.NOR51B_128	1.44e-06	49.3	COG0189@1|root,COG0189@2|Bacteria,1MVDU@1224|Proteobacteria,1RR7D@1236|Gammaproteobacteria,1J4UH@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	HJ	COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase)	PA1766	-	-	-	-	-	-	-	-	-	-	-	ATPgrasp_ST
k59_1836042_1	717772.THIAE_10465	1.36e-125	382.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,1RNB2@1236|Gammaproteobacteria,45ZT1@72273|Thiotrichales	72273|Thiotrichales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_305498_1	1410613.JNKF01000012_gene1318	2.48e-63	204.0	2DVZS@1|root,33XVN@2|Bacteria	2|Bacteria	S	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
k59_1774637_1	1537917.JU82_02110	2.79e-184	516.0	COG2010@1|root,COG2010@2|Bacteria,1PDTK@1224|Proteobacteria,42N5Z@68525|delta/epsilon subdivisions,2YMTR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
k59_1774637_2	1249480.B649_11125	7.96e-154	433.0	COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,42NZG@68525|delta/epsilon subdivisions,2YMBE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	cytochrome c oxidase, cbb3-type, subunit II	ccoO	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	iIT341.HP0145	FixO
k59_364645_1	522306.CAP2UW1_0964	8.1e-64	199.0	COG3290@1|root,COG3290@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9
k59_364645_2	159087.Daro_0401	4.93e-22	87.4	COG0640@1|root,COG0640@2|Bacteria,1MZPS@1224|Proteobacteria,2VUHJ@28216|Betaproteobacteria,2KX18@206389|Rhodocyclales	206389|Rhodocyclales	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
k59_775494_1	1249480.B649_10120	3.94e-50	175.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2YMI5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	cation transport ATPase	ccoI	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
k59_775494_2	709032.Sulku_2148	2.75e-82	246.0	COG0252@1|root,COG0252@2|Bacteria,1RHAW@1224|Proteobacteria,42SNH@68525|delta/epsilon subdivisions,2YQ20@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EJ	GlutRNAGln amidotransferase subunit D	-	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
k59_1424480_1	1537917.JU82_04350	1.24e-57	197.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,42MYN@68525|delta/epsilon subdivisions,2YMXA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	molybdopterin oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin,Molydop_binding
k59_485188_1	1249480.B649_01055	7.02e-87	263.0	COG1344@1|root,COG1344@2|Bacteria,1P7ZB@1224|Proteobacteria,42QS1@68525|delta/epsilon subdivisions,2YNAV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	flaC	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
k59_1363374_1	1537917.JU82_08350	1.01e-129	391.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,42KZ9@68525|delta/epsilon subdivisions,2YMS4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_188558_1	1249480.B649_04765	2.22e-48	164.0	COG3190@1|root,COG3190@2|Bacteria,1Q1CX@1224|Proteobacteria,42PAU@68525|delta/epsilon subdivisions,2YP0B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1774668_1	1537917.JU82_03840	1.06e-20	89.7	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,42MCI@68525|delta/epsilon subdivisions,2YMR4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
k59_1774668_2	709032.Sulku_0332	1.74e-79	243.0	COG1587@1|root,COG1587@2|Bacteria,1NMTP@1224|Proteobacteria,42T0U@68525|delta/epsilon subdivisions,2YPN4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Uroporphyrinogen-III synthase	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
k59_1424496_1	709032.Sulku_1387	1.56e-101	309.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,42PUI@68525|delta/epsilon subdivisions,2YN3E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	PFAM TrkA-N domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2,TrkA_N
k59_1836089_1	640081.Dsui_3334	1.22e-45	168.0	COG3437@1|root,COG5001@1|root,COG3437@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KVEE@206389|Rhodocyclales	206389|Rhodocyclales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,Response_reg
k59_662150_1	1537917.JU82_10935	7.3e-112	338.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2YN0B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
k59_1249241_1	1249480.B649_00620	1.17e-41	139.0	2AK71@1|root,31AX6@2|Bacteria,1Q6EC@1224|Proteobacteria,432ZM@68525|delta/epsilon subdivisions,2YSGS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1424507_1	2340.JV46_14900	1.89e-96	311.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,1J4NP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	DNA polymerase III, alpha subunit	dnaE	GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k59_775517_1	159087.Daro_3113	3.09e-115	339.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VHB0@28216|Betaproteobacteria,2KUX0@206389|Rhodocyclales	206389|Rhodocyclales	C	CoA-transferase family III	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
k59_775517_2	1121035.AUCH01000007_gene453	2.31e-28	109.0	COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,2VQ46@28216|Betaproteobacteria,2KWPX@206389|Rhodocyclales	206389|Rhodocyclales	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
k59_836780_1	159087.Daro_4003	2.16e-98	304.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2VH59@28216|Betaproteobacteria,2KVJZ@206389|Rhodocyclales	206389|Rhodocyclales	I	carboxylase	pccA	-	6.4.1.3	ko:K01965	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
k59_1598578_2	709032.Sulku_1950	2.06e-81	244.0	COG1871@1|root,COG1871@2|Bacteria,1RDDB@1224|Proteobacteria,43AIB@68525|delta/epsilon subdivisions,2YSY8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	-	-	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
k59_894363_1	1249480.B649_04780	4.3e-136	390.0	COG0730@1|root,COG0730@2|Bacteria,1MWX2@1224|Proteobacteria,42R15@68525|delta/epsilon subdivisions,2YNVA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k59_894363_2	1249480.B649_04785	5.23e-09	55.8	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,42M4I@68525|delta/epsilon subdivisions,2YMFT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_547612_1	1449345.JHWC01000005_gene1088	1.76e-25	100.0	COG1314@1|root,COG1314@2|Bacteria,1NJ1D@1224|Proteobacteria,42TKW@68525|delta/epsilon subdivisions,2YPUI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Preprotein translocase subunit SecG	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
k59_547616_1	1537917.JU82_08665	1.31e-139	405.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,42M7A@68525|delta/epsilon subdivisions,2YNCK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k59_1305488_1	1249480.B649_04040	8.28e-83	266.0	COG0715@1|root,COG0834@1|root,COG2199@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42MCD@68525|delta/epsilon subdivisions,2YN6K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	ET	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,NMT1,SBP_bac_3
k59_135388_2	709032.Sulku_0999	2.56e-80	244.0	COG1058@1|root,COG1058@2|Bacteria,1MVG6@1224|Proteobacteria,42R50@68525|delta/epsilon subdivisions,2YNX5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
k59_1659799_1	159087.Daro_0017	6.29e-171	481.0	COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,2VIBJ@28216|Betaproteobacteria,2KVAT@206389|Rhodocyclales	206389|Rhodocyclales	K	Transcriptional regulator	-	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
k59_547641_1	1123518.ARWI01000001_gene777	2.22e-46	161.0	COG0220@1|root,COG0220@2|Bacteria,1RIVI@1224|Proteobacteria,1S92K@1236|Gammaproteobacteria,463GS@72273|Thiotrichales	72273|Thiotrichales	J	tRNA (guanine-N7-)-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_547641_2	1265502.KB905931_gene1612	7.28e-37	135.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,2VHYE@28216|Betaproteobacteria,4AAV7@80864|Comamonadaceae	28216|Betaproteobacteria	E	TIGRFAM glutamine synthetase, type I	glnA	GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360	5.4.4.3,6.3.1.2	ko:K01915,ko:K20712	ko00220,ko00250,ko00627,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00627,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253,R06988,R09284	RC00010,RC01754,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k59_1427179_1	709032.Sulku_0014	8.43e-88	271.0	COG3203@1|root,COG3203@2|Bacteria,1QZ2N@1224|Proteobacteria,42QVI@68525|delta/epsilon subdivisions,2YP28@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_135401_1	159087.Daro_2974	2.32e-104	312.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,2VHBR@28216|Betaproteobacteria,2KV2X@206389|Rhodocyclales	206389|Rhodocyclales	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
k59_426227_1	420662.Mpe_A2678	4.82e-59	193.0	COG1414@1|root,COG1414@2|Bacteria,1QRZN@1224|Proteobacteria,2W96F@28216|Betaproteobacteria,1KNZV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	helix_turn_helix isocitrate lyase regulation	-	-	-	ko:K05818	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
k59_72084_1	159087.Daro_1221	3.64e-101	306.0	COG1305@1|root,COG1305@2|Bacteria,1MY5V@1224|Proteobacteria,2VKGI@28216|Betaproteobacteria,2KW58@206389|Rhodocyclales	206389|Rhodocyclales	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
k59_1073305_1	471854.Dfer_3322	9.29e-66	214.0	COG3287@1|root,COG3287@2|Bacteria,4NGTB@976|Bacteroidetes,47MAD@768503|Cytophagia	976|Bacteroidetes	S	FIST_C	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
k59_366622_1	1101195.Meth11DRAFT_1765	3.68e-51	174.0	COG1357@1|root,COG1357@2|Bacteria,1N7U9@1224|Proteobacteria,2VXNF@28216|Betaproteobacteria,2KNI4@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
k59_603845_1	1249480.B649_02600	1.01e-104	318.0	COG2199@1|root,COG3706@2|Bacteria,1MXAW@1224|Proteobacteria,42M6B@68525|delta/epsilon subdivisions,2YN3C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_896651_1	159087.Daro_0210	1.23e-83	256.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,2VH6W@28216|Betaproteobacteria,2KV8N@206389|Rhodocyclales	206389|Rhodocyclales	NU	Pilus assembly protein	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
k59_1305520_1	1454004.AW11_02652	7.67e-104	316.0	COG3046@1|root,COG3046@2|Bacteria,1MUHX@1224|Proteobacteria,2VHTR@28216|Betaproteobacteria,1KQGU@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Deoxyribodipyrimidine photo-lyase-related protein	-	-	-	ko:K06876	-	-	-	-	ko00000	-	-	-	DPRP
k59_250948_1	1163408.UU9_16656	1.25e-84	262.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,1RN2M@1236|Gammaproteobacteria,1X30V@135614|Xanthomonadales	135614|Xanthomonadales	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
k59_839162_1	1304883.KI912532_gene2775	3.43e-101	312.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,2VHH8@28216|Betaproteobacteria,2KUJF@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
k59_777679_1	709032.Sulku_1839	7.67e-99	302.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,42MEM@68525|delta/epsilon subdivisions,2YMWQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
k59_366637_1	709032.Sulku_1574	2.01e-208	587.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,42M81@68525|delta/epsilon subdivisions,2YMTF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_190645_1	709032.Sulku_0680	5.54e-118	357.0	COG0046@1|root,COG0046@2|Bacteria,1MYN4@1224|Proteobacteria,42M08@68525|delta/epsilon subdivisions,2YMHZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
k59_664855_1	1121035.AUCH01000016_gene2220	6.8e-21	83.6	COG4736@1|root,COG4736@2|Bacteria,1PUF6@1224|Proteobacteria,2VXME@28216|Betaproteobacteria,2KXN0@206389|Rhodocyclales	206389|Rhodocyclales	O	Cbb3-type cytochrome oxidase	ccoQ	-	-	ko:K00407	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixQ
k59_547705_1	318161.Sden_1684	1.98e-06	50.8	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RMA9@1236|Gammaproteobacteria,2QBBH@267890|Shewanellaceae	1236|Gammaproteobacteria	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
k59_547705_2	1165841.SULAR_09184	1.13e-67	207.0	COG0816@1|root,COG0816@2|Bacteria,1RJ6T@1224|Proteobacteria,42STA@68525|delta/epsilon subdivisions,2YPJV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
k59_547705_3	1165841.SULAR_06673	1.09e-19	87.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,42MAR@68525|delta/epsilon subdivisions,2YMC4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	ABC transporter	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_16157_1	1537917.JU82_01190	3.29e-104	306.0	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,42NZY@68525|delta/epsilon subdivisions,2YMSS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	-	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
k59_307695_1	1123020.AUIE01000027_gene4597	3.77e-83	271.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,1RPAV@1236|Gammaproteobacteria,1YD1R@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0034645,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0050896,GO:0051103,GO:0051287,GO:0051716,GO:0070403,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1901576	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	iEC55989_1330.EC55989_2701,iECABU_c1320.ECABU_c27320,iECIAI1_1343.ECIAI1_2469,iECO103_1326.ECO103_2930,iECO111_1330.ECO111_3141,iECO26_1355.ECO26_3464,iECSE_1348.ECSE_2702,iECW_1372.ECW_m2640,iEKO11_1354.EKO11_1317,iEcE24377_1341.EcE24377A_2698,iEcSMS35_1347.EcSMS35_2566,iWFL_1372.ECW_m2640,iYL1228.KPN_02758,ic_1306.c2945	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
k59_1017415_1	387092.NIS_1465	1.89e-64	208.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,42M2H@68525|delta/epsilon subdivisions,2YMM9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k59_426278_1	709032.Sulku_0350	3.62e-53	179.0	COG0628@1|root,COG0628@2|Bacteria,1PMAR@1224|Proteobacteria,42TGZ@68525|delta/epsilon subdivisions,2YR9I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k59_426278_2	1537917.JU82_03925	2.94e-111	337.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42MBE@68525|delta/epsilon subdivisions,2YNGN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	abc transporter atp-binding protein	-	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k59_547746_1	1304883.KI912532_gene567	8.16e-15	82.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria,2KVVC@206389|Rhodocyclales	206389|Rhodocyclales	T	COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Cache_3-Cache_2,HATPase_c,HisKA,Hpt,Response_reg
k59_956979_1	497964.CfE428DRAFT_3248	1.15e-20	92.0	COG2202@1|root,COG2202@2|Bacteria	2|Bacteria	T	Pas domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GAF,GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_9,Response_reg,Trans_reg_C,dCache_3
k59_839221_1	977880.RALTA_A3092	6.99e-129	378.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,2VHDZ@28216|Betaproteobacteria,1K2Y1@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
k59_664913_1	1249480.B649_10865	4.04e-82	249.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,42P3I@68525|delta/epsilon subdivisions,2YMYB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
k59_664913_2	1249480.B649_10860	2.06e-12	65.1	COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,42MZF@68525|delta/epsilon subdivisions,2YMQX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
k59_1718109_1	396588.Tgr7_0982	3.46e-28	110.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,1RM8G@1236|Gammaproteobacteria,1WXND@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
k59_1718109_2	1236542.BALM01000001_gene101	5.52e-110	330.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,1RMR2@1236|Gammaproteobacteria,2Q8GW@267890|Shewanellaceae	1236|Gammaproteobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008966,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019538,GO:0034641,GO:0034654,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046777,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	iSBO_1134.SBO_3206	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_1427300_1	1165841.SULAR_05278	2.37e-106	318.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42NES@68525|delta/epsilon subdivisions,2YMT3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Type II secretion system	ctsF	-	-	ko:K02455,ko:K12278	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
k59_1427300_2	1150621.SMUL_1934	7.9e-09	55.5	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,42PTX@68525|delta/epsilon subdivisions,2YMNS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
k59_1365803_1	1132855.KB913035_gene1208	1.35e-53	173.0	COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,2VH1Z@28216|Betaproteobacteria,2KKHK@206350|Nitrosomonadales	206350|Nitrosomonadales	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_1365803_2	1502770.JQMG01000001_gene1763	5.79e-55	174.0	COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,2VR4W@28216|Betaproteobacteria,2KMT3@206350|Nitrosomonadales	206350|Nitrosomonadales	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
k59_1252021_1	269799.Gmet_1218	5.23e-32	130.0	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42NFR@68525|delta/epsilon subdivisions,2X7KX@28221|Deltaproteobacteria,43T3C@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_4
k59_1659946_1	674977.VMC_02360	3.84e-68	233.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XSRH@135623|Vibrionales	135623|Vibrionales	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_9
k59_1017503_1	1537917.JU82_00575	1.53e-198	559.0	COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,42M8Q@68525|delta/epsilon subdivisions,2YMSH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome c oxidase accessory protein	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
k59_190742_1	1304883.KI912532_gene3030	1.01e-66	223.0	COG4656@1|root,COG4656@2|Bacteria,1PJVF@1224|Proteobacteria,2VM4P@28216|Betaproteobacteria,2KUV4@206389|Rhodocyclales	206389|Rhodocyclales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,Fer4_17,RnfC_N,SLBB
k59_839287_2	159087.Daro_2672	4.54e-77	250.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,2VHR1@28216|Betaproteobacteria,2KUJG@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k59_366734_2	243231.GSU1454	7.64e-12	66.6	COG1215@1|root,COG1215@2|Bacteria,1MXG7@1224|Proteobacteria,42MRD@68525|delta/epsilon subdivisions,2X5MW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
k59_1600741_1	1122139.KB907873_gene2771	5.39e-42	154.0	COG1232@1|root,COG1232@2|Bacteria,1R0KQ@1224|Proteobacteria,1S093@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	-	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
k59_135596_1	1121035.AUCH01000020_gene2622	9.45e-112	327.0	COG1208@1|root,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,2VIQG@28216|Betaproteobacteria,2KVDT@206389|Rhodocyclales	206389|Rhodocyclales	M	Nucleotidyl transferase	-	-	2.7.7.33	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R00956	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
k59_1838880_1	1165096.ARWF01000001_gene893	0.000543	42.4	COG1377@1|root,COG1377@2|Bacteria,1MUWI@1224|Proteobacteria,2VIH0@28216|Betaproteobacteria,2KMIP@206350|Nitrosomonadales	206350|Nitrosomonadales	N	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhB	-	-	ko:K02401	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_2
k59_1838880_2	1249480.B649_02165	2.64e-161	455.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,42MY7@68525|delta/epsilon subdivisions,2YMP6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
k59_1838880_3	709032.Sulku_0439	3.65e-225	622.0	COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,42N99@68525|delta/epsilon subdivisions,2YMDU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
k59_1252107_1	1249480.B649_10265	3.47e-43	144.0	2AK35@1|root,31ASX@2|Bacteria,1Q62J@1224|Proteobacteria,42W2T@68525|delta/epsilon subdivisions,2YQDE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1252107_2	1249480.B649_10270	5.22e-19	84.7	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,42MGU@68525|delta/epsilon subdivisions,2YMB7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
k59_1073474_1	477228.YO5_12192	3.32e-10	64.3	COG3258@1|root,COG3258@2|Bacteria,1MZJW@1224|Proteobacteria,1S2EF@1236|Gammaproteobacteria,1Z0N5@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	C	Protein of unknown function (DUF3365)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365
k59_896812_1	159087.Daro_4044	2.43e-38	136.0	COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,2VK6C@28216|Betaproteobacteria,2KVV0@206389|Rhodocyclales	206389|Rhodocyclales	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_896812_2	159087.Daro_4043	3.24e-27	107.0	COG0683@1|root,COG0683@2|Bacteria,1MVV2@1224|Proteobacteria,2VJE6@28216|Betaproteobacteria,2KUS7@206389|Rhodocyclales	206389|Rhodocyclales	E	amino acid	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_1776966_1	1165841.SULAR_06423	1.08e-128	372.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,42MCV@68525|delta/epsilon subdivisions,2YMK7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
k59_1427420_1	159087.Daro_1166	6.54e-25	102.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2VH9K@28216|Betaproteobacteria,2KWJY@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	HlyD_D23
k59_1427420_2	159087.Daro_1166	2.21e-77	242.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2VH9K@28216|Betaproteobacteria,2KWJY@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	HlyD_D23
k59_896832_1	1331660.L313_1656	2.1e-07	58.5	COG3107@1|root,COG3107@2|Bacteria,1QHQ2@1224|Proteobacteria,1TFDS@1236|Gammaproteobacteria,3NKSP@468|Moraxellaceae	1236|Gammaproteobacteria	M	LppC putative lipoprotein	-	-	-	ko:K07121	-	-	-	-	ko00000	-	-	-	LppC
k59_1718213_2	1537917.JU82_10395	8.45e-09	54.3	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,42MFU@68525|delta/epsilon subdivisions,2YMBZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	-	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
k59_957121_1	1249480.B649_11185	5.88e-86	265.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,42M5U@68525|delta/epsilon subdivisions,2YMQH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	molybdopterin biosynthesis	moeA2	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
k59_488026_1	1165841.SULAR_05703	3.72e-107	321.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,42KZA@68525|delta/epsilon subdivisions,2YMA9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
k59_896841_1	1165841.SULAR_07585	6.34e-63	211.0	COG1034@1|root,COG1034@2|Bacteria,1RCFT@1224|Proteobacteria,42NK4@68525|delta/epsilon subdivisions,2YNI6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G)	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4,Fer4_7,NADH-G_4Fe-4S_3
k59_72253_2	1485544.JQKP01000004_gene472	3.88e-67	215.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,2VIMV@28216|Betaproteobacteria,44V7W@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
k59_1622327_2	1249480.B649_05815	1.06e-47	163.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,42NHA@68525|delta/epsilon subdivisions,2YMYU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX1	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
k59_1278150_1	215803.DB30_7423	8.19e-85	269.0	COG1164@1|root,COG1164@2|Bacteria,1MWYN@1224|Proteobacteria,437WG@68525|delta/epsilon subdivisions,2X364@28221|Deltaproteobacteria,2YUG4@29|Myxococcales	28221|Deltaproteobacteria	E	Angiotensin-converting enzyme	-	-	3.4.15.1	ko:K01283	ko04614,ko04924,ko05142,ko05410,map04614,map04924,map05142,map05410	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	Peptidase_M2
k59_1158520_1	545276.KB898728_gene175	1.28e-42	156.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,1T1G7@1236|Gammaproteobacteria,1WX1Q@135613|Chromatiales	135613|Chromatiales	KT	Fis Family	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
k59_733700_1	62928.azo3787	6.16e-109	330.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,2VJ52@28216|Betaproteobacteria,2KV5T@206389|Rhodocyclales	206389|Rhodocyclales	C	Nickel-dependent hydrogenase	-	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
k59_1453220_1	709032.Sulku_0065	4.2e-63	218.0	COG4581@1|root,COG4581@2|Bacteria,1MVD6@1224|Proteobacteria,42PR3@68525|delta/epsilon subdivisions,2YN2Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Mitochondrial degradasome RNA helicase subunit C terminal	-	-	3.6.4.13	ko:K17675	-	-	-	-	ko00000,ko01000,ko03029	-	-	-	Helicase_C,SUV3_C
k59_691205_1	1165841.SULAR_00365	5.57e-132	384.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,42MFC@68525|delta/epsilon subdivisions,2YMN5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iIT341.HP0976	AAA_26,Aminotran_3
k59_1571042_1	709032.Sulku_2197	3.21e-91	274.0	COG1578@1|root,COG1578@2|Bacteria,1RI11@1224|Proteobacteria,42RA1@68525|delta/epsilon subdivisions,2YNYT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function DUF89	-	-	-	ko:K09116	-	-	-	-	ko00000	-	-	-	DUF89
k59_691208_1	1249480.B649_07510	2.05e-137	410.0	COG5001@1|root,COG5001@2|Bacteria,1R4H0@1224|Proteobacteria,43CII@68525|delta/epsilon subdivisions,2YTD5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_447613_1	666681.M301_0158	2.34e-220	634.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,2VH5Z@28216|Betaproteobacteria,2KMDC@206350|Nitrosomonadales	206350|Nitrosomonadales	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k59_1680844_1	296591.Bpro_3733	4.4e-08	54.3	COG3299@1|root,COG3299@2|Bacteria,1PYEJ@1224|Proteobacteria,2VRSP@28216|Betaproteobacteria,4AHNP@80864|Comamonadaceae	28216|Betaproteobacteria	S	Baseplate J-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
k59_1680844_2	582899.Hden_1235	1.1e-15	77.8	COG4381@1|root,COG4381@2|Bacteria,1Q2B4@1224|Proteobacteria,2UI5A@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Phage protein GP46	-	-	-	-	-	-	-	-	-	-	-	-	GP46
k59_273744_1	1249480.B649_00285	6.9e-99	300.0	COG3174@1|root,COG3174@2|Bacteria,1NDBI@1224|Proteobacteria,42QBM@68525|delta/epsilon subdivisions,2YNPT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	MgtC family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
k59_1391584_1	1537917.JU82_05280	1.53e-10	59.7	COG1971@1|root,COG1971@2|Bacteria,1NWBY@1224|Proteobacteria,42RE2@68525|delta/epsilon subdivisions,2YPGS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Probably functions as a manganese efflux pump	mntP	-	-	-	-	-	-	-	-	-	-	-	Mntp
k59_1391584_2	1537917.JU82_05290	1.36e-65	204.0	COG0726@1|root,COG0726@2|Bacteria,1RCWD@1224|Proteobacteria,42R0P@68525|delta/epsilon subdivisions,2YPBW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
k59_1214691_1	903818.KI912268_gene1509	1.36e-93	295.0	COG4206@1|root,COG4206@2|Bacteria	2|Bacteria	H	cobalamin-transporting ATPase activity	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_1626577_1	1249480.B649_05805	1.72e-86	265.0	COG0168@1|root,COG0168@2|Bacteria,1N412@1224|Proteobacteria,42MBI@68525|delta/epsilon subdivisions,2YMWN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Potassium uptake protein	ktrB	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
k59_921686_2	395494.Galf_0072	3.12e-38	141.0	COG0840@1|root,COG0840@2|Bacteria,1MWU2@1224|Proteobacteria,2VNA8@28216|Betaproteobacteria,44WCH@713636|Nitrosomonadales	28216|Betaproteobacteria	NT	SMART chemotaxis sensory transducer	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal
k59_1867352_1	709032.Sulku_0874	1.92e-130	387.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,42MGF@68525|delta/epsilon subdivisions,2YN0E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the UbiD family	menA	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0396	UbiD
k59_1574793_1	1232683.ADIMK_0959	3.03e-53	182.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,1RMQU@1236|Gammaproteobacteria,4662Y@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	COG0303 Molybdopterin biosynthesis enzyme	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
k59_736574_1	572480.Arnit_0214	5.87e-12	65.1	COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,42M0J@68525|delta/epsilon subdivisions,2YNAU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iIT341.HP1101	G6PD_C,G6PD_N
k59_736574_2	572480.Arnit_0215	1.82e-62	201.0	COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria,42RW5@68525|delta/epsilon subdivisions,2YT3G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	pgl	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
k59_450812_1	1249480.B649_02435	1.71e-09	56.6	COG2860@1|root,COG2860@2|Bacteria,1RHQN@1224|Proteobacteria,42R47@68525|delta/epsilon subdivisions,2YP8Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	UPF0126
k59_450812_2	709032.Sulku_0487	2.54e-104	303.0	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,42MR0@68525|delta/epsilon subdivisions,2YN9C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
k59_450812_3	709032.Sulku_0488	3.25e-24	101.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,42NN7@68525|delta/epsilon subdivisions,2YMKH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
k59_921748_1	1537917.JU82_10910	9.51e-125	378.0	COG1034@1|root,COG1034@2|Bacteria,1RCFT@1224|Proteobacteria,42NK4@68525|delta/epsilon subdivisions,2YNI6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G)	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4,Fer4_7,NADH-G_4Fe-4S_3
k59_921748_2	1249480.B649_01170	7.22e-37	138.0	COG1034@1|root,COG1034@2|Bacteria,1RCFT@1224|Proteobacteria,42NK4@68525|delta/epsilon subdivisions,2YNI6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G)	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4_10,Molybdopterin,NADH-G_4Fe-4S_3
k59_1800290_1	713586.KB900536_gene42	1.52e-146	436.0	COG1387@1|root,COG1387@2|Bacteria,1MYXV@1224|Proteobacteria,1TK7U@1236|Gammaproteobacteria,1X089@135613|Chromatiales	135613|Chromatiales	L	DNA polymerase X family	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8
k59_514168_1	1537994.JQFW01000050_gene2374	3.61e-08	60.8	COG2244@1|root,COG2244@2|Bacteria,1MXWW@1224|Proteobacteria,1SYNY@1236|Gammaproteobacteria,469M1@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Polysaccharide biosynthesis protein	wzx	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3
k59_632096_1	90814.KL370891_gene1657	3.58e-117	364.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,1RMIA@1236|Gammaproteobacteria,45ZMZ@72273|Thiotrichales	72273|Thiotrichales	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_5
k59_1800298_1	1537917.JU82_04070	4.27e-43	155.0	COG0778@1|root,COG0778@2|Bacteria,1Q0G9@1224|Proteobacteria,42QDE@68525|delta/epsilon subdivisions,2YMPN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_218313_1	232721.Ajs_1060	5.91e-24	105.0	COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,2VK7C@28216|Betaproteobacteria,4ABIY@80864|Comamonadaceae	28216|Betaproteobacteria	T	histidine kinase HAMP region domain protein	baeS	-	2.7.13.3	ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
k59_694895_1	159087.Daro_0926	2.47e-34	129.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VNJW@28216|Betaproteobacteria,2KW08@206389|Rhodocyclales	206389|Rhodocyclales	NT	Methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
k59_694895_2	497321.C664_16265	1.94e-44	155.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2VH0Q@28216|Betaproteobacteria,2KUIB@206389|Rhodocyclales	206389|Rhodocyclales	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1098638_1	709032.Sulku_1879	1.64e-149	429.0	COG1463@1|root,COG1463@2|Bacteria,1MU4B@1224|Proteobacteria,42RPB@68525|delta/epsilon subdivisions,2YP5G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	ABC-type transport system involved in resistance to organic solvents periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
k59_328144_2	1537917.JU82_08315	2.68e-66	211.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,42M5V@68525|delta/epsilon subdivisions,2YM81@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Cysteine desulfurase	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
k59_328151_2	717774.Marme_3752	1.5e-59	190.0	COG0120@1|root,COG0120@2|Bacteria,1MVGR@1224|Proteobacteria,1RNF8@1236|Gammaproteobacteria,1XH9C@135619|Oceanospirillales	135619|Oceanospirillales	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
k59_328155_1	709032.Sulku_0733	1.22e-61	191.0	COG1516@1|root,COG1516@2|Bacteria,1PSYY@1224|Proteobacteria,42V8K@68525|delta/epsilon subdivisions,2YQ35@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar protein FliS	fliS	-	-	ko:K02422	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliS
k59_1098662_1	1249480.B649_07710	1.54e-57	180.0	28QM5@1|root,319KE@2|Bacteria,1Q3DZ@1224|Proteobacteria,42X5X@68525|delta/epsilon subdivisions,2YQT9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1098662_2	709032.Sulku_0874	9.37e-24	99.4	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,42MGF@68525|delta/epsilon subdivisions,2YN0E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the UbiD family	menA	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0396	UbiD
k59_694939_1	709032.Sulku_1867	1.3e-126	373.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,42MV4@68525|delta/epsilon subdivisions,2YN13@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
k59_1744858_1	1165841.SULAR_00640	1.52e-19	81.3	2AMA7@1|root,31C55@2|Bacteria,1QGIU@1224|Proteobacteria,432YR@68525|delta/epsilon subdivisions,2YSPH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1744858_2	1123514.KB905902_gene231	7.61e-17	80.1	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RN5G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM ATPase associated with various cellular activities	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_694951_1	582744.Msip34_1974	1.12e-11	63.2	COG2995@1|root,COG2995@2|Bacteria,1RAQ9@1224|Proteobacteria,2WB3F@28216|Betaproteobacteria,2KNVU@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Paraquat-inducible protein A	-	-	-	ko:K03808	-	-	-	-	ko00000	-	-	-	PqiA
k59_694951_2	582744.Msip34_1973	2.46e-61	194.0	COG2995@1|root,COG2995@2|Bacteria,1MWG1@1224|Proteobacteria,2VMXT@28216|Betaproteobacteria,2KMYW@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Paraquat-inducible protein A	-	-	-	ko:K03808	-	-	-	-	ko00000	-	-	-	PqiA
k59_1048724_1	159087.Daro_1760	7.53e-71	216.0	COG0589@1|root,COG0589@2|Bacteria,1N02E@1224|Proteobacteria,2VU60@28216|Betaproteobacteria	28216|Betaproteobacteria	T	universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_1048724_2	159087.Daro_1759	3.23e-38	142.0	COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,2VI9F@28216|Betaproteobacteria,2KUMU@206389|Rhodocyclales	206389|Rhodocyclales	H	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
k59_1098686_1	1304883.KI912532_gene115	7.81e-30	117.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VHKE@28216|Betaproteobacteria,2KUKZ@206389|Rhodocyclales	206389|Rhodocyclales	P	E1-E2 ATPase	-	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
k59_1098686_2	85643.Tmz1t_2389	5.55e-35	132.0	COG0642@1|root,COG0642@2|Bacteria,1QTVA@1224|Proteobacteria,2VJU7@28216|Betaproteobacteria,2KZYW@206389|Rhodocyclales	206389|Rhodocyclales	T	Member of a two-component regulatory system	-	-	2.7.13.3	ko:K07644	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HATPase_c,HisKA
k59_986258_1	1122201.AUAZ01000010_gene2621	1.47e-59	198.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,1RM90@1236|Gammaproteobacteria,46DBI@72275|Alteromonadaceae	1236|Gammaproteobacteria	KT	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_4,Sigma54_activat
k59_921872_1	1304883.KI912532_gene1914	3.12e-40	134.0	COG0454@1|root,COG0456@2|Bacteria,1N7JM@1224|Proteobacteria,2VU1F@28216|Betaproteobacteria,2KX24@206389|Rhodocyclales	206389|Rhodocyclales	K	Protein of unknown function (DUF3579)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3579
k59_1626766_1	1249480.B649_01170	1.57e-110	338.0	COG1034@1|root,COG1034@2|Bacteria,1RCFT@1224|Proteobacteria,42NK4@68525|delta/epsilon subdivisions,2YNI6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G)	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4_10,Molybdopterin,NADH-G_4Fe-4S_3
k59_736656_1	1537917.JU82_01985	2.78e-97	293.0	COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2YMD8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	porA	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
k59_1214887_1	709032.Sulku_0446	2.89e-17	76.3	COG5501@1|root,COG5501@2|Bacteria,1RH4J@1224|Proteobacteria,42TET@68525|delta/epsilon subdivisions,2YPK6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Sulfur oxidation protein SoxY	-	-	-	ko:K17226	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxY
k59_1214887_2	1249480.B649_02200	4.01e-63	194.0	COG2033@1|root,COG2033@2|Bacteria,1NNT5@1224|Proteobacteria,42TKZ@68525|delta/epsilon subdivisions,2YPSG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	oxidation protein SoxZ	-	-	-	ko:K17227	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxZ
k59_695005_1	1249480.B649_03240	3.33e-122	358.0	COG2046@1|root,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,42NAI@68525|delta/epsilon subdivisions,2YME3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	sulfate adenylyltransferase	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
k59_1626799_1	1249480.B649_08060	8.57e-23	90.9	2AIWB@1|root,319DT@2|Bacteria,1Q2F3@1224|Proteobacteria,42VJD@68525|delta/epsilon subdivisions,2YQCE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1867474_1	1355374.JARU01000006_gene1783	2.94e-140	404.0	COG0517@1|root,COG1208@1|root,COG0517@2|Bacteria,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42MX5@68525|delta/epsilon subdivisions,2YMSQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)	ptmE	-	-	-	-	-	-	-	-	-	-	-	CBS,NTP_transferase
k59_632219_2	1249480.B649_02185	1.97e-74	234.0	COG5002@1|root,COG5002@2|Bacteria,1QUJ9@1224|Proteobacteria,42MEB@68525|delta/epsilon subdivisions,2YMXI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_1161685_1	1157708.KB907451_gene4866	4.5e-35	139.0	COG3299@1|root,COG3419@1|root,COG3299@2|Bacteria,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,2VHY8@28216|Betaproteobacteria,4ABJ6@80864|Comamonadaceae	28216|Betaproteobacteria	NU	Tfp pilus assembly protein tip-associated adhesin PilY1-like protein	-	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC,PA14
k59_576527_1	1537917.JU82_09545	1.39e-90	266.0	COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,42QW5@68525|delta/epsilon subdivisions,2YNWG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
k59_576527_2	1537917.JU82_09540	5.24e-06	44.3	COG0255@1|root,COG0255@2|Bacteria,1Q5ZI@1224|Proteobacteria,42VCR@68525|delta/epsilon subdivisions,2YQ6C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
k59_1684065_1	1270196.JCKI01000005_gene2926	9.86e-09	59.3	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	BNR_2
k59_1684065_2	159087.Daro_0556	8e-30	111.0	2BJ0W@1|root,32D9G@2|Bacteria,1PWYC@1224|Proteobacteria,2WCGA@28216|Betaproteobacteria,2KZ7D@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1214935_1	1283284.AZUK01000001_gene1133	2.81e-49	169.0	2DBDI@1|root,2Z8M4@2|Bacteria,1R655@1224|Proteobacteria,1S76V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1214935_2	997352.HMPREF9419_1697	1.24e-10	62.4	COG1403@1|root,COG1403@2|Bacteria,4NTJI@976|Bacteroidetes,2FZQJ@200643|Bacteroidia	976|Bacteroidetes	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_736710_1	709032.Sulku_0055	2.04e-36	140.0	COG3144@1|root,COG3144@2|Bacteria,1PBUJ@1224|Proteobacteria,42VQM@68525|delta/epsilon subdivisions,2YQGT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Flagellar hook-length control protein FliK	-	-	-	-	-	-	-	-	-	-	-	-	Flg_hook
k59_861005_2	159087.Daro_1978	1.1e-60	195.0	COG1639@1|root,COG1639@2|Bacteria,1RASR@1224|Proteobacteria,2VR0D@28216|Betaproteobacteria,2KWNY@206389|Rhodocyclales	206389|Rhodocyclales	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_1161711_1	1337936.IJ00_23345	6.03e-13	72.4	COG0400@1|root,COG0400@2|Bacteria,1G525@1117|Cyanobacteria,1HKIK@1161|Nostocales	1117|Cyanobacteria	S	PFAM phospholipase Carboxylesterase	sll1284	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
k59_1161711_2	525897.Dbac_0876	4.27e-46	151.0	2B3E9@1|root,31W34@2|Bacteria,1MZ95@1224|Proteobacteria,42U85@68525|delta/epsilon subdivisions,2WQIR@28221|Deltaproteobacteria,2MCCW@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_218463_1	159087.Daro_2932	4.11e-107	324.0	COG1944@1|root,COG1944@2|Bacteria,1MV7K@1224|Proteobacteria,2VHZY@28216|Betaproteobacteria,2KV2Z@206389|Rhodocyclales	206389|Rhodocyclales	O	redox protein, regulator of disulfide bond formation	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	YcaO
k59_1457117_1	1123020.AUIE01000041_gene3200	5.05e-08	51.6	2EHK0@1|root,33BBV@2|Bacteria,1NGIK@1224|Proteobacteria,1SGHN@1236|Gammaproteobacteria,1YH2A@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	-	-	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	-
k59_1457117_2	1218352.B597_005165	3.71e-28	113.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1RWNF@1236|Gammaproteobacteria,1Z0ZR@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_4,PAS_9
k59_450997_1	709032.Sulku_1956	7.11e-12	67.4	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42N03@68525|delta/epsilon subdivisions,2YNMG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	PFAM Methyl-accepting chemotaxis protein (MCP) signaling domain	-	-	-	ko:K03406,ko:K05875	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,MCPsignal
k59_450997_2	1537917.JU82_00200	2.01e-28	104.0	2AK43@1|root,31ATX@2|Bacteria,1Q64B@1224|Proteobacteria,432D7@68525|delta/epsilon subdivisions,2YSJA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_161832_1	1125863.JAFN01000001_gene3394	4.98e-123	365.0	COG0644@1|root,COG0644@2|Bacteria,1MVU6@1224|Proteobacteria,42PTE@68525|delta/epsilon subdivisions,2WK6W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	HI0933-like protein	-	-	-	ko:K00313	-	-	-	-	ko00000,ko01000	-	-	-	DAO,FAD_binding_3
k59_1575131_1	1304883.KI912532_gene938	1.69e-153	438.0	COG0683@1|root,COG0683@2|Bacteria,1MXR4@1224|Proteobacteria,2VHP9@28216|Betaproteobacteria,2KXYT@206389|Rhodocyclales	206389|Rhodocyclales	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_1800527_1	709032.Sulku_0331	1.21e-177	506.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,42M0I@68525|delta/epsilon subdivisions,2YMV0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
k59_1867562_1	717773.Thicy_0280	2.94e-106	330.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,1RNRX@1236|Gammaproteobacteria,45ZT3@72273|Thiotrichales	72273|Thiotrichales	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
k59_1867562_2	29486.NJ56_02365	2.1e-11	63.2	COG3709@1|root,COG3709@2|Bacteria,1RGXZ@1224|Proteobacteria,1S3VA@1236|Gammaproteobacteria,41FQH@629|Yersinia	1236|Gammaproteobacteria	F	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)	phnN	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006015,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019200,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019634,GO:0019637,GO:0019674,GO:0019693,GO:0033863,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046391,GO:0046483,GO:0046496,GO:0046835,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.23	ko:K05774	ko00030,map00030	-	R06836	RC00002	ko00000,ko00001,ko01000	-	-	iAF1260.b4094,iB21_1397.B21_03926,iBWG_1329.BWG_3809,iECBD_1354.ECBD_3936,iECB_1328.ECB_03966,iECDH10B_1368.ECDH10B_4285,iECDH1ME8569_1439.ECDH1ME8569_3953,iECD_1391.ECD_03966,iEKO11_1354.EKO11_4224,iEcDH1_1363.EcDH1_3897,iEcolC_1368.EcolC_3932,iJO1366.b4094,iSSON_1240.SSON_4270,iUMNK88_1353.UMNK88_4960,iY75_1357.Y75_RS21315	AAA_18,Guanylate_kin
k59_736786_1	1172562.HCN_2009	7.99e-17	80.5	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,42N10@68525|delta/epsilon subdivisions,2YMIF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	LU	DNA processing protein	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
k59_736786_2	1249480.B649_02930	2.29e-54	180.0	COG2861@1|root,COG2861@2|Bacteria,1N3JP@1224|Proteobacteria,42RJN@68525|delta/epsilon subdivisions,2YP6V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Divergent polysaccharide deacetylase	-	-	-	ko:K09798	-	-	-	-	ko00000	-	-	-	Polysacc_deac_2
k59_1867582_1	709032.Sulku_0955	3.47e-61	196.0	COG0177@1|root,COG0177@2|Bacteria,1RAK3@1224|Proteobacteria,42M4V@68525|delta/epsilon subdivisions,2YNKT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	tigr02757	-	-	-	-	-	-	-	-	-	-	-	-	DUF2400
k59_1867582_2	709032.Sulku_0954	5.69e-11	62.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,42M3C@68525|delta/epsilon subdivisions,2YMHJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
k59_986523_1	1537917.JU82_02790	2.05e-138	399.0	2AGMT@1|root,316V3@2|Bacteria,1PY20@1224|Proteobacteria,42NND@68525|delta/epsilon subdivisions,2YMQB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	pgbB	-	-	-	-	-	-	-	-	-	-	-	PGBA_C,PQQ_2
k59_736801_3	1537917.JU82_10600	2.81e-59	190.0	COG0723@1|root,COG0723@2|Bacteria,1MZ7A@1224|Proteobacteria,42N9F@68525|delta/epsilon subdivisions,2YNBZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
k59_328411_1	1249480.B649_01400	4.54e-124	370.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,42NF8@68525|delta/epsilon subdivisions,2YMBT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	ATP-dependent DNA helicase	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
k59_1800601_1	1537917.JU82_09590	4.25e-93	281.0	COG1373@1|root,COG1373@2|Bacteria,1QP8R@1224|Proteobacteria,42SQ9@68525|delta/epsilon subdivisions,2YPG4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	ATPase (AAA	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14
k59_1827558_1	399742.Ent638_0909	8.95e-14	68.9	COG1555@1|root,COG1555@2|Bacteria,1N6Q3@1224|Proteobacteria,1SC7U@1236|Gammaproteobacteria,3X2S4@547|Enterobacter	1236|Gammaproteobacteria	L	TIGRFAM competence protein ComEA helix-hairpin-helix	comEA	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3
k59_1827558_2	887898.HMPREF0551_0308	8.4e-27	107.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,2VHHW@28216|Betaproteobacteria,1K3Q4@119060|Burkholderiaceae	28216|Betaproteobacteria	NU	twitching motility protein	pilT	-	-	ko:K02669,ko:K12203	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2,3.A.7.10.1,3.A.7.9.1	-	-	T2SSE
k59_1708763_1	1537917.JU82_08350	8.93e-154	455.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,42KZ9@68525|delta/epsilon subdivisions,2YMS4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_1708768_1	1417296.U879_06825	9.16e-37	137.0	COG3550@1|root,COG3550@2|Bacteria,1N458@1224|Proteobacteria,2TUX1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	protein related to capsule biosynthesis enzymes	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
k59_828861_1	159087.Daro_0274	2.54e-45	152.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2VHYN@28216|Betaproteobacteria,2KU8C@206389|Rhodocyclales	206389|Rhodocyclales	E	ABC-type branched-chain amino acid transport systems, ATPase component	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
k59_1769592_1	1537917.JU82_04755	1.05e-92	275.0	COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,42SI3@68525|delta/epsilon subdivisions,2YRUU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Membrane	-	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
k59_126787_1	1249480.B649_02605	6.01e-12	65.9	COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,42N08@68525|delta/epsilon subdivisions,2YMRG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	folylpolyglutamate synthase	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
k59_126787_2	709032.Sulku_0522	3.36e-41	151.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,42N8X@68525|delta/epsilon subdivisions,2YMGZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_538699_1	159087.Daro_4105	1.92e-29	110.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,2VHNK@28216|Betaproteobacteria,2KV5R@206389|Rhodocyclales	206389|Rhodocyclales	D	involved in chromosome partitioning	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
k59_538699_2	159087.Daro_4106	5.72e-123	355.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,2VIG0@28216|Betaproteobacteria,2KU8M@206389|Rhodocyclales	206389|Rhodocyclales	K	Belongs to the ParB family	spoOJ	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
k59_948837_1	553218.CAMRE0001_0050	4.53e-16	73.9	2AIY8@1|root,319FY@2|Bacteria,1Q2MH@1224|Proteobacteria,42VY9@68525|delta/epsilon subdivisions,2YQHM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_948837_2	563040.Saut_0847	2.69e-29	116.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YMMN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1124985_1	563040.Saut_0388	3.32e-70	217.0	2AI7Y@1|root,318NF@2|Bacteria,1Q0NR@1224|Proteobacteria,42SAU@68525|delta/epsilon subdivisions,2YPMQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1358130_2	159087.Daro_0617	2.7e-44	151.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,2VSPK@28216|Betaproteobacteria,2KWAY@206389|Rhodocyclales	206389|Rhodocyclales	S	Phosphoribosyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
k59_538713_1	1168067.JAGP01000001_gene735	4.52e-12	62.4	COG0745@1|root,COG0745@2|Bacteria,1RDNP@1224|Proteobacteria,1S47I@1236|Gammaproteobacteria,460U7@72273|Thiotrichales	72273|Thiotrichales	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
k59_538713_2	983545.Glaag_1300	1.11e-08	59.7	COG3143@1|root,COG3143@2|Bacteria,1NIV6@1224|Proteobacteria,1RNG2@1236|Gammaproteobacteria,464ER@72275|Alteromonadaceae	1236|Gammaproteobacteria	NT	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)	cheZ	GO:0001539,GO:0003674,GO:0003824,GO:0004721,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006928,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0032991,GO:0036211,GO:0040011,GO:0042578,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071704,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0097588,GO:0098561,GO:0140096,GO:1901564	-	ko:K03414	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheZ
k59_1536218_1	717772.THIAE_03020	1.43e-67	221.0	COG2951@1|root,COG3409@1|root,COG2951@2|Bacteria,COG3409@2|Bacteria,1MUZ3@1224|Proteobacteria,1RMQ6@1236|Gammaproteobacteria,4605G@72273|Thiotrichales	72273|Thiotrichales	M	TIGRFAM lytic murein transglycosylase	-	-	-	ko:K08305	-	-	-	-	ko00000,ko01000,ko01011	-	GH103	-	PG_binding_1,SLT_2
k59_1710942_1	1537917.JU82_01670	2.3e-108	345.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,43DMZ@68525|delta/epsilon subdivisions,2YMMS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_1769631_1	387093.SUN_2068	9.32e-49	163.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,42NMR@68525|delta/epsilon subdivisions,2YN8M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k59_1769631_2	387093.SUN_2069	2.97e-41	144.0	COG0147@1|root,COG0147@2|Bacteria,1R5Y8@1224|Proteobacteria,42P2B@68525|delta/epsilon subdivisions,2YMFR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EH	component I	pabB	-	2.6.1.85	ko:K01665	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	Chorismate_bind
k59_1358148_1	1249480.B649_07115	3.16e-150	441.0	COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,42PHY@68525|delta/epsilon subdivisions,2YMBI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG0155 Sulfite reductase, beta subunit (hemoprotein)	-	-	1.7.7.1,1.8.7.1	ko:K00366,ko:K00392	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00531	R00790,R00859,R03600	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
k59_1652433_1	686340.Metal_0128	4.11e-39	139.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,1RQQT@1236|Gammaproteobacteria,1XDJD@135618|Methylococcales	135618|Methylococcales	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
k59_1299667_1	1537917.JU82_04670	1.6e-128	376.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2YMQG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
k59_300871_1	580332.Slit_2859	2.78e-86	264.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,2VIT9@28216|Betaproteobacteria,44VKF@713636|Nitrosomonadales	28216|Betaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
k59_479241_1	387093.SUN_0016	5.23e-106	313.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,42NFK@68525|delta/epsilon subdivisions,2YNST@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_1769668_1	2340.JV46_12810	3.68e-08	53.5	COG1763@1|root,COG1763@2|Bacteria,1RD3Q@1224|Proteobacteria,1S72P@1236|Gammaproteobacteria,1J6RE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Molybdopterin-guanine dinucleotide biosynthesis protein	mobB	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363	2.7.7.77	ko:K03753,ko:K13818	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	iB21_1397.B21_03691,iBWG_1329.BWG_3527,iECBD_1354.ECBD_4174,iECDH1ME8569_1439.ECDH1ME8569_3728,iEcDH1_1363.EcDH1_4130,iJO1366.b3856,iSbBS512_1146.SbBS512_E4328,iY75_1357.Y75_RS17805	MobB
k59_1769668_2	1304883.KI912532_gene2260	3.94e-75	229.0	COG0746@1|root,COG0746@2|Bacteria,1RH3M@1224|Proteobacteria,2VQR2@28216|Betaproteobacteria,2KW8P@206389|Rhodocyclales	206389|Rhodocyclales	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
k59_831218_1	269797.Mbar_A0538	1.75e-36	136.0	COG1449@1|root,arCOG03278@2157|Archaea,2XVDW@28890|Euryarchaeota,2N9CV@224756|Methanomicrobia	224756|Methanomicrobia	G	Glycosyl hydrolase family 57	-	-	3.2.1.1	ko:K07405	ko00500,ko01100,map00500,map01100	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH57	-	Glyco_hydro_57
k59_1125072_1	318167.Sfri_2416	0.000166	50.1	COG1629@1|root,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,2Q8IQ@267890|Shewanellaceae	1236|Gammaproteobacteria	P	TonB-dependent receptor plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_1652475_1	1537917.JU82_08660	5.72e-30	112.0	COG1387@1|root,COG1387@2|Bacteria,1RCEG@1224|Proteobacteria,42MIM@68525|delta/epsilon subdivisions,2YMFF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	histidinol phosphate phosphatase	hisJ	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP,PHP_C
k59_300892_2	1537917.JU82_02990	5.08e-25	99.0	COG0704@1|root,COG0704@2|Bacteria,1Q5TJ@1224|Proteobacteria,42STN@68525|delta/epsilon subdivisions,2YPRM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	PhoU family	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
k59_1476610_1	1304883.KI912532_gene2091	1.72e-15	72.8	2ENFG@1|root,33G2V@2|Bacteria,1NPDC@1224|Proteobacteria,2W4J3@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_831247_1	765912.Thimo_2055	7.03e-32	129.0	COG2203@1|root,COG3829@1|root,COG4191@1|root,COG5001@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WVV9@135613|Chromatiales	135613|Chromatiales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,PAS,PAS_3,PAS_9,Phosphonate-bd,Response_reg
k59_1182829_2	709032.Sulku_0385	1.7e-100	295.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,42QYK@68525|delta/epsilon subdivisions,2YNZ8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	ABC transporter, ATP-binding protein	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran
k59_1182842_1	522306.CAP2UW1_0121	3.5e-92	288.0	COG1639@1|root,COG2199@1|root,COG1639@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2VHDQ@28216|Betaproteobacteria	28216|Betaproteobacteria	T	RESPONSE REGULATOR receiver	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HDOD,Response_reg
k59_538858_1	1458427.BAWN01000006_gene441	3.27e-47	171.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,4A9PA@80864|Comamonadaceae	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,dCache_1
k59_1299758_1	360094.PXO_04599	1e-30	116.0	COG4875@1|root,COG4875@2|Bacteria,1RK48@1224|Proteobacteria,1T05J@1236|Gammaproteobacteria,1X7CG@135614|Xanthomonadales	135614|Xanthomonadales	S	Calcium/calmodulin dependent protein kinase II association domain	-	-	-	-	-	-	-	-	-	-	-	-	CaMKII_AD
k59_126961_1	1537917.JU82_11520	4.52e-118	357.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,42MC5@68525|delta/epsilon subdivisions,2YM83@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
k59_889364_1	159087.Daro_1848	8.85e-29	108.0	COG5490@1|root,COG5490@2|Bacteria,1R4SV@1224|Proteobacteria,2VQP2@28216|Betaproteobacteria,2KW96@206389|Rhodocyclales	206389|Rhodocyclales	S	Phasin protein	-	-	-	-	-	-	-	-	-	-	-	-	Phasin_2
k59_1536375_1	1000565.METUNv1_01931	2.05e-99	300.0	COG3920@1|root,COG3920@2|Bacteria,1MVPJ@1224|Proteobacteria,2VN2J@28216|Betaproteobacteria,2KXQE@206389|Rhodocyclales	206389|Rhodocyclales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_2,PAS_9
k59_656102_2	1397527.Q670_10480	2.35e-27	107.0	COG3707@1|root,COG3707@2|Bacteria,1MXDV@1224|Proteobacteria,1S3YY@1236|Gammaproteobacteria,1XJT0@135619|Oceanospirillales	135619|Oceanospirillales	T	response regulator	nasT	-	-	ko:K07183	-	-	-	-	ko00000,ko02022	-	-	-	ANTAR,Response_reg
k59_1182877_1	1408422.JHYF01000017_gene1871	2e-21	93.6	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,2490U@186801|Clostridia,36EG3@31979|Clostridiaceae	186801|Clostridia	Q	TIGRFAM amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_1182877_2	1380600.AUYN01000010_gene847	6.73e-31	122.0	COG1020@1|root,COG1020@2|Bacteria,4NDV5@976|Bacteroidetes,1HXHR@117743|Flavobacteriia	976|Bacteroidetes	Q	Belongs to the ATP-dependent AMP-binding enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_12,Methyltransf_21,PP-binding,Thioesterase
k59_656111_1	159087.Daro_2180	2.89e-160	459.0	COG3522@1|root,COG3522@2|Bacteria,1MXKE@1224|Proteobacteria,2VHVK@28216|Betaproteobacteria,2KXAP@206389|Rhodocyclales	206389|Rhodocyclales	S	Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE	-	-	-	ko:K11893	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_VasE
k59_243497_1	243233.MCA0510	7.35e-88	273.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,1S14K@1236|Gammaproteobacteria,1XG9Y@135618|Methylococcales	135618|Methylococcales	J	tRNA synthetases class I (E and Q), catalytic domain	-	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
k59_243497_2	1123360.thalar_01321	7.03e-07	50.1	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,2TR4T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
k59_596073_1	1249480.B649_08910	2.22e-107	312.0	COG0692@1|root,COG0692@2|Bacteria,1MV80@1224|Proteobacteria,42MYK@68525|delta/epsilon subdivisions,2YMMB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	-	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
k59_1007888_1	1249480.B649_05800	1.57e-74	246.0	COG0659@1|root,COG0664@1|root,COG0659@2|Bacteria,COG0664@2|Bacteria,1MVWV@1224|Proteobacteria,42MMU@68525|delta/epsilon subdivisions,2YTMR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	STAS domain	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp,cNMP_binding
k59_1182895_1	72019.SARC_02809T0	1.89e-06	51.6	COG0147@1|root,KOG1224@2759|Eukaryota,38EFT@33154|Opisthokonta	33154|Opisthokonta	J	synthase	ABZ1	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008153,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0042537,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046482,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0046820,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.6.1.85	ko:K13950	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind,GATase
k59_300973_1	929558.SMGD1_2071	1.01e-52	184.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42S84@68525|delta/epsilon subdivisions,2YPD4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_8,dCache_3
k59_889395_1	709032.Sulku_0597	6.09e-97	290.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,42MMG@68525|delta/epsilon subdivisions,2YMCT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
k59_419508_1	1123514.KB905899_gene607	2.26e-55	183.0	COG2890@1|root,COG2890@2|Bacteria,1MX8Q@1224|Proteobacteria,1RPHQ@1236|Gammaproteobacteria,45ZV3@72273|Thiotrichales	72273|Thiotrichales	J	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue	prmB	-	2.1.1.298	ko:K07320	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03009	-	-	-	MTS
k59_419508_2	521674.Plim_1982	4.79e-17	76.6	COG0521@1|root,COG0521@2|Bacteria,2IYUD@203682|Planctomycetes	203682|Planctomycetes	H	Molybdenum cofactor biosynthesis	-	-	2.7.7.75	ko:K03638,ko:K03831	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
k59_360215_1	1300005.R9RH65_9CAUD	1.93e-80	258.0	4QEQT@10239|Viruses,4QYJH@35237|dsDNA viruses  no RNA stage,4QQ1B@28883|Caudovirales,4QNPW@10744|Podoviridae	10744|Podoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1358311_1	387093.SUN_2042	8.21e-52	174.0	COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,42N08@68525|delta/epsilon subdivisions,2YMRG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	folylpolyglutamate synthase	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
k59_1358311_2	387093.SUN_2043	2.79e-22	91.7	2BTJ1@1|root,32NRK@2|Bacteria,1Q3XC@1224|Proteobacteria,42RS4@68525|delta/epsilon subdivisions,2YPVI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Lipopolysaccharide-assembly	-	-	-	-	-	-	-	-	-	-	-	-	LptE
k59_1830174_1	1537917.JU82_05300	1.74e-111	323.0	COG2928@1|root,COG2928@2|Bacteria,1PKH9@1224|Proteobacteria,42XVN@68525|delta/epsilon subdivisions,2YQSF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
k59_1830174_2	1249480.B649_08885	4.84e-147	422.0	COG0265@1|root,COG0265@2|Bacteria,1NVFS@1224|Proteobacteria,42Z4E@68525|delta/epsilon subdivisions,2YRIR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Peptidase s1	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
k59_1243282_2	1249480.B649_09785	2.92e-37	128.0	COG0811@1|root,COG0811@2|Bacteria,1RK2P@1224|Proteobacteria,42TPV@68525|delta/epsilon subdivisions,2YPGE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Biopolymer transporter ExbB	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k59_10060_1	929558.SMGD1_2686	2.22e-57	189.0	COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,42NEN@68525|delta/epsilon subdivisions,2YN4D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k59_10060_2	1537917.JU82_08200	1.74e-94	283.0	COG0770@1|root,COG0770@2|Bacteria,1Q5GZ@1224|Proteobacteria,42RQ8@68525|delta/epsilon subdivisions,2YP4M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity	-	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	-
k59_243574_1	338969.Rfer_0259	2.49e-29	120.0	COG3303@1|root,COG3303@2|Bacteria,1PEVM@1224|Proteobacteria,2VMWI@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
k59_656189_1	1537917.JU82_10940	0.0	879.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,42NGD@68525|delta/epsilon subdivisions,2YMP5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M)	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k59_831391_1	159087.Daro_0913	3.51e-169	488.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,2VH8W@28216|Betaproteobacteria,2KUTU@206389|Rhodocyclales	206389|Rhodocyclales	L	DNA helicase	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
k59_656208_1	631362.Thi970DRAFT_01933	5.05e-39	138.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,1RMUC@1236|Gammaproteobacteria,1WWSB@135613|Chromatiales	135613|Chromatiales	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
k59_1243320_1	402777.KB235903_gene1840	1.32e-28	119.0	COG0642@1|root,COG2202@1|root,COG4191@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria,1G09B@1117|Cyanobacteria,1HI0U@1150|Oscillatoriales	1117|Cyanobacteria	T	HWE histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
k59_10084_1	640081.Dsui_0411	7.04e-138	403.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,2VITP@28216|Betaproteobacteria,2KYDP@206389|Rhodocyclales	206389|Rhodocyclales	E	ABC-type dipeptide transport system, periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k59_656213_1	1304883.KI912532_gene390	1.18e-109	344.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,2KUIU@206389|Rhodocyclales	206389|Rhodocyclales	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_656213_2	1163617.SCD_n00486	2.01e-24	102.0	COG0025@1|root,COG0025@2|Bacteria,1N07S@1224|Proteobacteria,2VP23@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
k59_360253_1	709032.Sulku_0923	2.46e-20	82.0	COG2442@1|root,COG2442@2|Bacteria,1NH1S@1224|Proteobacteria,42X0V@68525|delta/epsilon subdivisions,2YT77@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
k59_360253_2	1537917.JU82_07190	1.01e-62	193.0	COG4634@1|root,COG4634@2|Bacteria,1RH7A@1224|Proteobacteria,42U78@68525|delta/epsilon subdivisions,2YSFQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_360253_3	1537917.JU82_07195	8.94e-130	378.0	COG1362@1|root,COG1362@2|Bacteria,1NT1D@1224|Proteobacteria,42MN0@68525|delta/epsilon subdivisions,2YRFV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	M18 family aminopeptidase	-	-	3.4.11.21	ko:K01267	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	Peptidase_M18
k59_1418431_2	317025.Tcr_1194	1.17e-70	226.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,45ZT5@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_10091_1	1249480.B649_05780	2.75e-57	186.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,42M0C@68525|delta/epsilon subdivisions,2YM8W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
k59_1127400_1	159087.Daro_3999	5.71e-69	215.0	COG4235@1|root,COG4235@2|Bacteria,1MY4J@1224|Proteobacteria,2VQ05@28216|Betaproteobacteria,2KW83@206389|Rhodocyclales	206389|Rhodocyclales	O	Cytochrome c-type biogenesis protein	-	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	TPR_16
k59_481606_1	598659.NAMH_1510	2.81e-38	147.0	COG2200@1|root,COG3829@1|root,COG4753@1|root,COG2200@2|Bacteria,COG3829@2|Bacteria,COG4753@2|Bacteria,1N299@1224|Proteobacteria	1224|Proteobacteria	T	EAL domain	yfgF	GO:0000302,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008081,GO:0008150,GO:0009628,GO:0009636,GO:0009987,GO:0010035,GO:0016020,GO:0016021,GO:0016787,GO:0016788,GO:0031224,GO:0033554,GO:0034059,GO:0034599,GO:0034614,GO:0035690,GO:0036293,GO:0036294,GO:0042221,GO:0042493,GO:0042542,GO:0042578,GO:0043900,GO:0044425,GO:0044464,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070301,GO:0070482,GO:0070887,GO:0071111,GO:0071236,GO:0071453,GO:0071454,GO:0071944,GO:0097237,GO:1900190,GO:1901700,GO:1901701	-	-	-	-	-	-	-	-	-	-	EAL,MASE1
k59_1067538_1	709032.Sulku_2261	1.4e-22	95.5	COG0845@1|root,COG0845@2|Bacteria,1QMYR@1224|Proteobacteria,42WWX@68525|delta/epsilon subdivisions,2YR01@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	RND family efflux transporter, MFP subunit	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
k59_1067538_2	1249480.B649_01975	9.2e-44	156.0	COG1538@1|root,COG1538@2|Bacteria,1Q5X2@1224|Proteobacteria,43200@68525|delta/epsilon subdivisions,2YS78@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_1712939_1	387093.SUN_2276	2.43e-58	196.0	COG3203@1|root,COG3203@2|Bacteria,1QZ2N@1224|Proteobacteria,42QVI@68525|delta/epsilon subdivisions,2YP28@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1010110_1	584708.Apau_2154	3.49e-16	83.6	COG0642@1|root,COG3614@1|root,COG5002@1|root,COG0642@2|Bacteria,COG3614@2|Bacteria,COG5002@2|Bacteria,3T9SP@508458|Synergistetes	508458|Synergistetes	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg,SBP_bac_3
k59_951139_1	709032.Sulku_0662	5.48e-82	253.0	COG2199@1|root,COG3706@2|Bacteria,1MVCZ@1224|Proteobacteria,43AWN@68525|delta/epsilon subdivisions,2YT3U@29547|Epsilonproteobacteria	1224|Proteobacteria	T	TIGRFAM diguanylate cyclase (GGDEF) domain	dosC	GO:0003674,GO:0003824,GO:0005488,GO:0008144,GO:0016740,GO:0016772,GO:0016779,GO:0019825,GO:0020037,GO:0036094,GO:0042165,GO:0043167,GO:0043169,GO:0046906,GO:0048037,GO:0052621,GO:0070025,GO:0097159,GO:1901363	2.7.7.65	ko:K13069,ko:K13590,ko:K18967	ko04112,map04112	-	R08057	-	ko00000,ko00001,ko01000,ko02000	9.B.34.1.1	-	-	GGDEF,Protoglobin
k59_598151_1	1150626.PHAMO_180136	1.42e-39	150.0	2DNU8@1|root,32Z5M@2|Bacteria,1RGT6@1224|Proteobacteria,2UJGI@28211|Alphaproteobacteria,2JZ4Y@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1451352_1	709032.Sulku_1739	2e-85	275.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2YRKW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0474 Cation transport ATPase	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
k59_1795169_1	1484479.DI14_02070	2.98e-32	124.0	COG2199@1|root,COG2199@2|Bacteria,1VTBQ@1239|Firmicutes,4ITW1@91061|Bacilli	91061|Bacilli	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_384342_1	1165841.SULAR_02328	4.29e-32	124.0	COG0715@1|root,COG0715@2|Bacteria,1NV0U@1224|Proteobacteria,42SS6@68525|delta/epsilon subdivisions,2YPMU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	-
k59_688814_1	387093.SUN_2354	9.59e-88	274.0	COG2303@1|root,COG2303@2|Bacteria,1MU3F@1224|Proteobacteria,42MWP@68525|delta/epsilon subdivisions,2YNEC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Oxidoreductase	-	-	1.1.99.3	ko:K06151	ko00030,ko01100,ko01120,map00030,map01100,map01120	-	R01741	RC00084	ko00000,ko00001,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
k59_1043272_1	5286.M7XNF4	2.35e-19	92.4	COG0642@1|root,KOG0519@2759|Eukaryota,38E1E@33154|Opisthokonta,3NXNC@4751|Fungi,3UYDH@5204|Basidiomycota,2YC8A@29000|Pucciniomycotina	4751|Fungi	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,MHYT,Response_reg
k59_269191_1	1249480.B649_10605	1.38e-99	295.0	COG3267@1|root,COG3267@2|Bacteria,1R16B@1224|Proteobacteria,42SY7@68525|delta/epsilon subdivisions,2YPRP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
k59_384355_1	1485544.JQKP01000010_gene829	9.61e-35	128.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,2VIM9@28216|Betaproteobacteria,44VDW@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
k59_156972_1	159087.Daro_1415	5.63e-121	350.0	COG1348@1|root,COG1348@2|Bacteria,1MVTE@1224|Proteobacteria,2VIK4@28216|Betaproteobacteria,2KUME@206389|Rhodocyclales	206389|Rhodocyclales	P	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein	nifH	-	1.18.6.1	ko:K02588	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_NifH
k59_1275896_1	159087.Daro_1097	2.61e-25	102.0	COG2141@1|root,COG2141@2|Bacteria,1MVF0@1224|Proteobacteria,2VHXM@28216|Betaproteobacteria,2KUN5@206389|Rhodocyclales	206389|Rhodocyclales	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
k59_1275896_2	159087.Daro_0277	1.13e-47	153.0	COG0851@1|root,COG0851@2|Bacteria,1N6QD@1224|Proteobacteria,2VTX1@28216|Betaproteobacteria,2KX3N@206389|Rhodocyclales	206389|Rhodocyclales	D	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell	minE	-	-	ko:K03608	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinE
k59_1156337_1	1165841.SULAR_10099	6.88e-101	302.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,42NF2@68525|delta/epsilon subdivisions,2YMGD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
k59_1156337_2	929558.SMGD1_1512	3.05e-84	259.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,42KZG@68525|delta/epsilon subdivisions,2YMKQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
k59_1451422_1	709032.Sulku_1153	4.99e-110	318.0	COG2346@1|root,COG2346@2|Bacteria,1N1UU@1224|Proteobacteria,43B84@68525|delta/epsilon subdivisions,2YRXC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
k59_1678832_1	1168067.JAGP01000001_gene223	6.72e-97	299.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,460C8@72273|Thiotrichales	72273|Thiotrichales	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
k59_1620246_1	1537917.JU82_06470	1.34e-76	233.0	COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,42TJ2@68525|delta/epsilon subdivisions,2YPJ2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
k59_1620246_2	1249480.B649_02360	9.05e-101	293.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,42QU1@68525|delta/epsilon subdivisions,2YNVF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP1038	DHquinase_II
k59_445383_1	159087.Daro_3473	4.41e-132	384.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,2VISR@28216|Betaproteobacteria,2KUDX@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
k59_1323169_1	1165841.SULAR_09309	3.79e-81	253.0	COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,42PB4@68525|delta/epsilon subdivisions,2YNJ9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	ko:K15576	ko00910,ko02010,map00910,map02010	M00438	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16.1,3.A.1.16.2	-	-	NMT1_2
k59_384429_1	1249480.B649_02380	1.87e-58	182.0	29NSE@1|root,309QF@2|Bacteria,1QT0N@1224|Proteobacteria,42TIY@68525|delta/epsilon subdivisions,2YP79@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_322295_1	1537917.JU82_07645	2.33e-83	250.0	COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,42MAM@68525|delta/epsilon subdivisions,2YT9B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	ABC transporter	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
k59_322295_2	1249480.B649_03865	1.49e-49	164.0	COG2177@1|root,COG2177@2|Bacteria,1R85B@1224|Proteobacteria,42PX3@68525|delta/epsilon subdivisions,2YNQW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Cell division protein FtsX	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	-
k59_1737495_1	631362.Thi970DRAFT_03464	8.74e-62	219.0	COG0642@1|root,COG0834@1|root,COG5002@1|root,COG0642@2|Bacteria,COG0834@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1T1JE@1236|Gammaproteobacteria,1X2RK@135613|Chromatiales	135613|Chromatiales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HAMP,HATPase_c,HisKA,Hpt,MASE1,PAS_9,Response_reg
k59_31382_1	1537917.JU82_11875	1.38e-139	422.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,42N8X@68525|delta/epsilon subdivisions,2YMGZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_1502063_1	62928.azo2825	1.09e-81	254.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,2VH78@28216|Betaproteobacteria,2KXQK@206389|Rhodocyclales	206389|Rhodocyclales	H	Molybdopterin biosynthesis	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
k59_571776_1	1218076.BAYB01000028_gene4736	2.33e-20	82.8	COG0051@1|root,COG0051@2|Bacteria,1RGWF@1224|Proteobacteria,2VSDQ@28216|Betaproteobacteria,1K7MU@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
k59_571776_2	159087.Daro_0319	7.37e-75	228.0	COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,2VJ3V@28216|Betaproteobacteria,2KV3R@206389|Rhodocyclales	206389|Rhodocyclales	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
k59_157070_2	395494.Galf_0283	1.67e-103	306.0	COG1493@1|root,COG1493@2|Bacteria,1NNN5@1224|Proteobacteria,2VJCH@28216|Betaproteobacteria,44V87@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
k59_1323221_1	2340.JV46_20220	1.08e-33	136.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1J80W@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	PAS S-box diguanylate cyclase domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	5TM-5TMR_LYT,EAL,GGDEF,PAS,PAS_4,PAS_9,dCache_1
k59_801657_1	105559.Nwat_1252	1.69e-47	162.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,1RP09@1236|Gammaproteobacteria,1WX0B@135613|Chromatiales	135613|Chromatiales	O	heat shock protein DnaJ	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
k59_688990_1	709032.Sulku_1748	2.85e-109	318.0	COG4123@1|root,COG4123@2|Bacteria,1RDSC@1224|Proteobacteria,42RIN@68525|delta/epsilon subdivisions,2YP8V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	MTS
k59_384490_1	709032.Sulku_1947	4.82e-20	95.5	COG3290@1|root,COG3614@1|root,COG4191@1|root,COG3290@2|Bacteria,COG3614@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42R1U@68525|delta/epsilon subdivisions,2YNX6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,PAS_9
k59_1862362_1	1288494.EBAPG3_27020	4.92e-61	199.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,2VHIP@28216|Betaproteobacteria,371XT@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
k59_89500_1	717772.THIAE_01795	7.34e-81	250.0	COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,1RMU0@1236|Gammaproteobacteria,45ZZM@72273|Thiotrichales	72273|Thiotrichales	H	Belongs to the prokaryotic GSH synthase family	gshB	-	6.3.2.3	ko:K01920	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00497,R10994	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	GSH-S_ATP,GSH-S_N
k59_1678922_1	1537917.JU82_09775	3.6e-156	457.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	mmoS	-	-	ko:K20972	ko02025,map02025	-	-	-	ko00000,ko00001,ko01001,ko02022	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,CHASE5,HATPase_c,HisKA,Hpt,Response_reg
k59_1451504_2	709032.Sulku_0202	1.71e-62	194.0	COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,42QS6@68525|delta/epsilon subdivisions,2YN2M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
k59_1737589_1	1121035.AUCH01000012_gene3004	9.6e-12	67.4	COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,2VIBZ@28216|Betaproteobacteria,2KUXF@206389|Rhodocyclales	206389|Rhodocyclales	GM	epimerase dehydratase	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	Epimerase,NAD_binding_10
k59_1737589_2	83406.HDN1F_27620	6.38e-21	90.9	COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,1RPFJ@1236|Gammaproteobacteria,1J53S@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate	cca	GO:0001680,GO:0003674,GO:0003824,GO:0004652,GO:0004810,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016437,GO:0016740,GO:0016772,GO:0016779,GO:0031123,GO:0034470,GO:0034641,GO:0034660,GO:0042245,GO:0042780,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0070566,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1990817	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
k59_979378_1	1137799.GZ78_04670	2.6e-97	292.0	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,1RMAT@1236|Gammaproteobacteria,1XHPM@135619|Oceanospirillales	135619|Oceanospirillales	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
k59_1862400_1	709032.Sulku_0358	2.49e-99	309.0	COG4206@1|root,COG4206@2|Bacteria	709032.Sulku_0358|-	H	cobalamin-transporting ATPase activity	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	-
k59_979385_1	709032.Sulku_1906	2.5e-67	223.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42SS2@68525|delta/epsilon subdivisions,2YRAM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	CZB,MCPsignal
k59_445537_1	395494.Galf_0803	1.54e-39	136.0	COG0546@1|root,COG0546@2|Bacteria,1RDA7@1224|Proteobacteria,2VIZ2@28216|Betaproteobacteria,44UYP@713636|Nitrosomonadales	28216|Betaproteobacteria	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 1	ppaX	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_445537_2	395494.Galf_0804	3.39e-77	238.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,2VH94@28216|Betaproteobacteria,44V82@713636|Nitrosomonadales	28216|Betaproteobacteria	OU	Peptidase family S49	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
k59_157169_1	929558.SMGD1_1599	2.25e-99	295.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,42PYJ@68525|delta/epsilon subdivisions,2YREA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
k59_1620410_1	1121935.AQXX01000101_gene677	1.17e-64	204.0	COG4278@1|root,COG4278@2|Bacteria,1RBTS@1224|Proteobacteria,1S5B5@1236|Gammaproteobacteria,1XJGE@135619|Oceanospirillales	135619|Oceanospirillales	H	phenylacetate-CoA ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_915420_1	709032.Sulku_0319	4.05e-68	237.0	COG1361@1|root,COG1361@2|Bacteria,1QVSF@1224|Proteobacteria,42QQ6@68525|delta/epsilon subdivisions,2YTBA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_322468_1	159087.Daro_3414	8.62e-113	335.0	COG2114@1|root,COG2114@2|Bacteria,1QWGZ@1224|Proteobacteria,2WEJJ@28216|Betaproteobacteria,2KZV9@206389|Rhodocyclales	206389|Rhodocyclales	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
k59_1679029_1	1249480.B649_03985	1.23e-77	247.0	2AN97@1|root,32J0R@2|Bacteria,1PCA3@1224|Proteobacteria,42T7U@68525|delta/epsilon subdivisions,2YPPF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Flg_hook
k59_571872_1	748280.NH8B_1883	1.06e-14	73.2	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VMUZ@28216|Betaproteobacteria,2KSJN@206351|Neisseriales	206351|Neisseriales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,TPR_12
k59_571872_2	1122165.AUHS01000019_gene1550	2.8e-45	157.0	COG3287@1|root,COG3287@2|Bacteria,1MVUZ@1224|Proteobacteria,1RY7N@1236|Gammaproteobacteria,1JFUN@118969|Legionellales	118969|Legionellales	S	FIST_C	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
k59_1156577_1	1249480.B649_04820	4.19e-85	263.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,42NM8@68525|delta/epsilon subdivisions,2YNFK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
k59_979488_1	159087.Daro_0816	8.25e-15	72.8	COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,2VIEA@28216|Betaproteobacteria,2KUS5@206389|Rhodocyclales	206389|Rhodocyclales	C	nitrite reductase NAD(P)H	nirB	-	1.7.1.15	ko:K00362	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2
k59_979488_2	159087.Daro_0815	1.9e-24	99.4	COG0547@1|root,COG0547@2|Bacteria,1QJ8Q@1224|Proteobacteria,2VH2D@28216|Betaproteobacteria,2KVGU@206389|Rhodocyclales	206389|Rhodocyclales	E	glycosyl transferase family	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_trans_3N,Glycos_transf_3
k59_1043598_1	709032.Sulku_0823	5.46e-123	365.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,42MW6@68525|delta/epsilon subdivisions,2YNJR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	potassium channel protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans,Ion_trans_2,TrkA_C,TrkA_N
k59_1679071_1	395494.Galf_1146	2.46e-70	228.0	COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,2VI12@28216|Betaproteobacteria,44V1X@713636|Nitrosomonadales	28216|Betaproteobacteria	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
k59_1679071_2	395494.Galf_1147	1.06e-12	62.8	COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,2VSPN@28216|Betaproteobacteria,44VZM@713636|Nitrosomonadales	28216|Betaproteobacteria	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himD	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k59_979497_1	1249480.B649_05705	4.58e-81	250.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,42NJJ@68525|delta/epsilon subdivisions,2YM8Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
k59_1276195_2	340177.Cag_0681	1.43e-31	115.0	COG1487@1|root,COG1487@2|Bacteria	2|Bacteria	S	nuclease activity	vapC	-	-	-	-	-	-	-	-	-	-	-	PIN
k59_1276195_3	937777.Deipe_3604	1.48e-05	46.6	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1WIRD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Vitamin B12 dependent methionine synthase activation	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
k59_1093793_1	990073.ATHU01000001_gene262	1.61e-32	130.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1NQKX@1224|Proteobacteria,43CB3@68525|delta/epsilon subdivisions,2YTAN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG2200 FOG EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,sCache_2
k59_731773_1	1194165.CAJF01000022_gene3077	6.37e-06	51.6	COG0472@1|root,COG0472@2|Bacteria,2GIT7@201174|Actinobacteria,4FKC0@85023|Microbacteriaceae	201174|Actinobacteria	M	Glycosyl transferase family 4	rfe	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0034645,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
k59_1620504_1	532075.B3VCV3_9CAUD	1.38e-41	150.0	4QAM2@10239|Viruses,4QV3W@35237|dsDNA viruses  no RNA stage,4QPGK@28883|Caudovirales,4QNW0@10744|Podoviridae	10744|Podoviridae	S	exonuclease activity	-	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360	-	-	-	-	-	-	-	-	-	-	-
k59_731779_1	395494.Galf_2829	8.24e-104	307.0	COG1091@1|root,COG1091@2|Bacteria,1MUXM@1224|Proteobacteria,2VI50@28216|Betaproteobacteria,44VGA@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
k59_509369_2	1235797.C816_04059	0.000992	45.8	COG0664@1|root,COG0664@2|Bacteria,1V28H@1239|Firmicutes	1239|Firmicutes	K	- catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
k59_856550_1	159087.Daro_0057	1.13e-104	304.0	COG0560@1|root,COG0560@2|Bacteria,1MZPG@1224|Proteobacteria,2VHDT@28216|Betaproteobacteria,2KVYK@206389|Rhodocyclales	206389|Rhodocyclales	E	phosphoserine phosphatase	thrH	-	2.7.1.39,3.1.3.3	ko:K02203	ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00680,map01100,map01110,map01120,map01130,map01230	M00018	R00582,R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD,Hydrolase
k59_1097291_2	709032.Sulku_1315	5.49e-44	145.0	2AK69@1|root,31AW9@2|Bacteria,1Q6BQ@1224|Proteobacteria,432TB@68525|delta/epsilon subdivisions,2YST5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1213414_1	159087.Daro_4004	3.29e-130	382.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2VIYF@28216|Betaproteobacteria,2KU70@206389|Rhodocyclales	206389|Rhodocyclales	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	pccB	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
k59_1455360_1	709032.Sulku_0027	1.63e-119	349.0	COG2038@1|root,COG2038@2|Bacteria,1NZFH@1224|Proteobacteria,42NRQ@68525|delta/epsilon subdivisions,2YNQ9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	phosphoribosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DBI_PRT
k59_449562_1	159087.Daro_2490	6.69e-09	61.6	COG0715@1|root,COG4191@1|root,COG0715@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VMN8@28216|Betaproteobacteria,2KUPQ@206389|Rhodocyclales	206389|Rhodocyclales	T	Histidine kinase	-	-	2.7.13.3	ko:K13040	ko02020,map02020	M00514	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Phosphonate-bd
k59_575034_1	159087.Daro_2776	7.88e-100	295.0	COG0346@1|root,COG0346@2|Bacteria,1MUWY@1224|Proteobacteria,2VKV3@28216|Betaproteobacteria,2KUG0@206389|Rhodocyclales	206389|Rhodocyclales	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	1.13.11.2	ko:K00446	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
k59_735531_1	367737.Abu_2179	3.8e-09	60.1	COG2304@1|root,COG2931@1|root,COG4932@1|root,COG2304@2|Bacteria,COG2931@2|Bacteria,COG4932@2|Bacteria,1MU7T@1224|Proteobacteria,42T9J@68525|delta/epsilon subdivisions,2YRPW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
k59_735531_2	1537917.JU82_11600	5.45e-13	67.4	COG3672@1|root,COG3672@2|Bacteria,1RDQS@1224|Proteobacteria,42QWJ@68525|delta/epsilon subdivisions,2YNVX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Bacterial transglutaminase-like cysteine proteinase BTLCP	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C93
k59_92670_1	1168067.JAGP01000001_gene76	8.13e-28	115.0	COG3174@1|root,COG3174@2|Bacteria,1RA19@1224|Proteobacteria,1S78D@1236|Gammaproteobacteria,463IM@72273|Thiotrichales	72273|Thiotrichales	S	Domain of unknown function (DUF4010)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010
k59_630849_1	411477.PARMER_00087	7.97e-43	155.0	292UM@1|root,2ZQC9@2|Bacteria,4NTGF@976|Bacteroidetes,2FMY7@200643|Bacteroidia,22WZB@171551|Porphyromonadaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1160422_1	929558.SMGD1_0378	6.29e-54	191.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2YMB9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	chemotaxis protein	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
k59_735537_1	1537917.JU82_05730	5.67e-127	370.0	COG0731@1|root,COG0731@2|Bacteria,1QG36@1224|Proteobacteria,42M82@68525|delta/epsilon subdivisions,2YN42@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
k59_326763_1	1537917.JU82_00650	1.29e-94	290.0	COG1293@1|root,COG1293@2|Bacteria,1R54S@1224|Proteobacteria,42MYG@68525|delta/epsilon subdivisions,2YT8X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	RNA-binding protein homologous to eukaryotic snRNP	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
k59_35772_1	644076.SCH4B_4163	2.7e-18	88.6	COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,2TSP0@28211|Alphaproteobacteria,4NBIJ@97050|Ruegeria	28211|Alphaproteobacteria	M	HlyD membrane-fusion protein of T1SS	-	-	-	ko:K02022	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD,HlyD_3
k59_920053_1	1249627.D779_4090	2.04e-101	317.0	COG4166@1|root,COG4166@2|Bacteria,1R87R@1224|Proteobacteria,1S4M3@1236|Gammaproteobacteria,1WWN6@135613|Chromatiales	135613|Chromatiales	E	Extracellular solute-binding protein, family 5	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
k59_1743015_1	317025.Tcr_1937	3.02e-82	271.0	COG0715@1|root,COG0834@1|root,COG2199@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG3706@2|Bacteria,1MXAW@1224|Proteobacteria,1RZ41@1236|Gammaproteobacteria,462HX@72273|Thiotrichales	72273|Thiotrichales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,NMT1,SBP_bac_3
k59_272584_1	1537917.JU82_02265	1.37e-45	157.0	COG0679@1|root,COG0679@2|Bacteria,1PHSS@1224|Proteobacteria,42M30@68525|delta/epsilon subdivisions,2YN5E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	auxin efflux carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
k59_1624794_1	709032.Sulku_0468	1.61e-100	298.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,42MNA@68525|delta/epsilon subdivisions,2YMK1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	OU	signal peptide peptidase SppA, 36K type	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
k59_7193_1	1121035.AUCH01000003_gene1227	2.86e-46	167.0	COG0840@1|root,COG4564@1|root,COG0840@2|Bacteria,COG4564@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,2KUJI@206389|Rhodocyclales	206389|Rhodocyclales	NT	Methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,sCache_2
k59_535172_1	1249480.B649_08230	7.47e-77	234.0	COG0775@1|root,COG0775@2|Bacteria,1MY5S@1224|Proteobacteria,42MBG@68525|delta/epsilon subdivisions,2YMHE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	pfs	-	3.2.2.30,3.2.2.9	ko:K18284	ko00130,ko00270,ko01100,ko01110,ko01230,map00130,map00270,map01100,map01110,map01230	M00034,M00609	R00194,R01401,R10668	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
k59_1239417_1	396588.Tgr7_1333	3.42e-35	130.0	COG1684@1|root,COG1684@2|Bacteria,1NIF4@1224|Proteobacteria,1RMYW@1236|Gammaproteobacteria,1WWVK@135613|Chromatiales	135613|Chromatiales	N	Role in flagellar biosynthesis	-	-	-	ko:K02421	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1
k59_1061810_2	1283079.M1I895_9CAUD	1.38e-10	61.6	4QBIX@10239|Viruses,4QUUX@35237|dsDNA viruses  no RNA stage,4QQG7@28883|Caudovirales,4QNPQ@10744|Podoviridae	10744|Podoviridae	S	sequence-specific DNA binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_709058_1	709032.Sulku_0759	4.26e-172	489.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,42KZA@68525|delta/epsilon subdivisions,2YMA9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
k59_1766700_2	709032.Sulku_0430	1.27e-16	82.0	COG1729@1|root,COG1729@2|Bacteria,1R162@1224|Proteobacteria,43D7I@68525|delta/epsilon subdivisions,2YTGX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	-
k59_1121597_1	90814.KL370892_gene2182	4.71e-43	144.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,1S25H@1236|Gammaproteobacteria,460V2@72273|Thiotrichales	72273|Thiotrichales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
k59_1121597_2	981336.F944_03074	5.3e-97	295.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,1RN6U@1236|Gammaproteobacteria,3NK1R@468|Moraxellaceae	1236|Gammaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	e_coli_core.b3732,iAF1260.b3732,iAPECO1_1312.APECO1_2729,iB21_1397.B21_03560,iBWG_1329.BWG_3423,iE2348C_1286.E2348C_4042,iEC042_1314.EC042_4119,iEC55989_1330.EC55989_4207,iECABU_c1320.ECABU_c42160,iECBD_1354.ECBD_4300,iECB_1328.ECB_03616,iECDH10B_1368.ECDH10B_3919,iECDH1ME8569_1439.ECDH1ME8569_3620,iECD_1391.ECD_03616,iECED1_1282.ECED1_4422,iECH74115_1262.ECH74115_5168,iECIAI1_1343.ECIAI1_3916,iECIAI39_1322.ECIAI39_4336,iECNA114_1301.ECNA114_3881,iECO103_1326.ECO103_4426,iECO111_1330.ECO111_4566,iECO26_1355.ECO26_4846,iECOK1_1307.ECOK1_4181,iECP_1309.ECP_3931,iECS88_1305.ECS88_4154,iECSE_1348.ECSE_4022,iECSF_1327.ECSF_3580,iECSP_1301.ECSP_4782,iECUMN_1333.ECUMN_4262,iECW_1372.ECW_m4035,iECs_1301.ECs4674,iEKO11_1354.EKO11_4613,iETEC_1333.ETEC_4023,iEcDH1_1363.EcDH1_4235,iEcE24377_1341.EcE24377A_4247,iEcSMS35_1347.EcSMS35_4100,iEcolC_1368.EcolC_4262,iG2583_1286.G2583_4528,iJO1366.b3732,iJR904.b3732,iLF82_1304.LF82_0194,iNRG857_1313.NRG857_18585,iPC815.YPO4121,iSFV_1184.SFV_3758,iSF_1195.SF3812,iSFxv_1172.SFxv_4154,iSSON_1240.SSON_3887,iS_1188.S3956,iSbBS512_1146.SbBS512_E4189,iUMN146_1321.UM146_18850,iUMNK88_1353.UMNK88_4544,iUTI89_1310.UTI89_C4285,iWFL_1372.ECW_m4035,iY75_1357.Y75_RS18410,iZ_1308.Z5230,ic_1306.c4658	ATP-synt_ab,ATP-synt_ab_N
k59_63810_1	1165841.SULAR_03527	6.85e-108	335.0	COG0209@1|root,COG0693@1|root,COG0209@2|Bacteria,COG0693@2|Bacteria,1N0E3@1224|Proteobacteria,42QEY@68525|delta/epsilon subdivisions,2YNM2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Ribonucleotide reductase, barrel domain	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC
k59_767858_1	1535422.ND16A_2082	6.84e-82	254.0	COG2801@1|root,COG2801@2|Bacteria,1MXKK@1224|Proteobacteria,1RSMZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	PFAM Integrase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_63816_1	1249480.B649_00710	1.07e-05	46.6	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42MTX@68525|delta/epsilon subdivisions,2YMNH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	pseC	-	2.6.1.92	ko:K15895	ko00520,map00520	-	R09825	RC00006,RC00781	ko00000,ko00001,ko01000	-	-	-	DegT_DnrJ_EryC1
k59_63816_2	709032.Sulku_0152	6.5e-130	372.0	COG1083@1|root,COG1083@2|Bacteria,1QACI@1224|Proteobacteria,42QBP@68525|delta/epsilon subdivisions,2YNAX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	CMP-N-acetylneuraminic acid synthetase	pseF	-	2.7.7.43,2.7.7.81	ko:K00983,ko:K15899	ko00520,ko01100,map00520,map01100	-	R01117,R04215,R09843	RC00152	ko00000,ko00001,ko01000	-	-	-	CTP_transf_3
k59_63816_3	525898.Sdel_2211	9.63e-90	275.0	COG3980@1|root,COG3980@2|Bacteria,1Q330@1224|Proteobacteria,42P4J@68525|delta/epsilon subdivisions,2YMEH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	pseudaminic acid biosynthesis-associated protein PseG	pseG	-	3.6.1.57	ko:K15897	ko00520,map00520	-	R09834	RC00005,RC00078	ko00000,ko00001,ko01000	-	-	-	Glyco_tran_28_C
k59_1414801_2	709032.Sulku_1649	2e-81	245.0	COG1051@1|root,COG1051@2|Bacteria,1PNK8@1224|Proteobacteria,42YE5@68525|delta/epsilon subdivisions,2YR8Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	NUDIX domain	-	-	3.6.1.62,3.6.1.64	ko:K16855	ko00230,ko03018,map00230,map03018	-	R00961,R10235,R10815	RC00002	ko00000,ko00001,ko01000,ko03019	-	-	-	NUDIX
k59_7248_1	1249480.B649_02560	2.2e-57	186.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,42N1R@68525|delta/epsilon subdivisions,2YMRZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_7248_2	1249480.B649_02555	7.85e-68	212.0	COG0115@1|root,COG0115@2|Bacteria,1N3ZD@1224|Proteobacteria,42TNN@68525|delta/epsilon subdivisions,2YPU5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EH	Branched-chain amino acid aminotransferase	-	-	4.1.3.38	ko:K02619	ko00790,map00790	-	R05553	RC01843,RC02148	ko00000,ko00001,ko01000	-	-	-	Aminotran_4
k59_298362_1	709032.Sulku_1646	9.72e-21	96.3	COG1033@1|root,COG1033@2|Bacteria	2|Bacteria	S	growth of symbiont in host cell	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_1649369_1	555778.Hneap_1377	1.91e-132	404.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,1WWJI@135613|Chromatiales	135613|Chromatiales	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k59_1649375_1	1121035.AUCH01000012_gene2963	2.54e-72	226.0	COG1560@1|root,COG1560@2|Bacteria,1Q41N@1224|Proteobacteria,2VKN0@28216|Betaproteobacteria,2KUY8@206389|Rhodocyclales	206389|Rhodocyclales	M	acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
k59_1533083_1	709032.Sulku_0835	4.8e-84	273.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2YNQF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0474 Cation transport ATPase	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3,Na_H_Exchanger
k59_1766761_1	1537917.JU82_02980	4.5e-166	477.0	COG0642@1|root,COG2205@2|Bacteria,1QUJ7@1224|Proteobacteria,43BJF@68525|delta/epsilon subdivisions,2YNM7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,sCache_like
k59_1239517_1	709032.Sulku_2049	2.5e-87	273.0	COG0068@1|root,COG0068@2|Bacteria,1Q0S6@1224|Proteobacteria,42SF1@68525|delta/epsilon subdivisions,2YPJ0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	HypF finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HYPF
k59_652747_1	439235.Dalk_0055	5.12e-95	294.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,42YVY@68525|delta/epsilon subdivisions,2WU2P@28221|Deltaproteobacteria,2MMYM@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Acetyl-CoA dehydrogenase C-terminal like	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_592768_1	1188252.AJYK01000090_gene684	1.08e-12	70.9	COG5276@1|root,COG5276@2|Bacteria,1R8AF@1224|Proteobacteria,1S8X1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_945525_1	1385517.N800_12095	2.68e-65	203.0	COG4681@1|root,COG4681@2|Bacteria,1RDR9@1224|Proteobacteria,1S43N@1236|Gammaproteobacteria,1X64X@135614|Xanthomonadales	135614|Xanthomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YaeQ
k59_180893_1	1123518.ARWI01000001_gene773	2.99e-232	649.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,1RMD1@1236|Gammaproteobacteria,45ZRY@72273|Thiotrichales	72273|Thiotrichales	E	TIGRFAM glutamine synthetase, type I	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k59_1061903_1	1121035.AUCH01000012_gene2992	4.54e-62	207.0	COG0715@1|root,COG2199@1|root,COG0715@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2WGZJ@28216|Betaproteobacteria,2KVQZ@206389|Rhodocyclales	206389|Rhodocyclales	T	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,NMT1,PAS_4
k59_1179970_1	1249480.B649_05105	6.25e-98	297.0	COG3203@1|root,COG3203@2|Bacteria,1QZ2J@1224|Proteobacteria,42UFK@68525|delta/epsilon subdivisions,2YQ0J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	outer membrane porin, OprD family	-	-	-	-	-	-	-	-	-	-	-	-	OprD
k59_1649421_1	864051.BurJ1DRAFT_2348	4.45e-22	100.0	COG0642@1|root,COG2205@2|Bacteria,1N58A@1224|Proteobacteria,2VHVP@28216|Betaproteobacteria,1KN51@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Histidine kinase	yfhK	-	2.7.13.3	ko:K07711	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
k59_1649424_1	1249480.B649_01680	2.36e-44	155.0	COG1776@1|root,COG1776@2|Bacteria,1RICK@1224|Proteobacteria,42NMU@68525|delta/epsilon subdivisions,2YMV4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Chemotaxis phosphatase CheX	-	-	-	-	-	-	-	-	-	-	-	-	CheX
k59_1649426_1	1304883.KI912532_gene789	2.46e-36	128.0	COG1187@1|root,COG1187@2|Bacteria,1MU6M@1224|Proteobacteria,2VIXH@28216|Betaproteobacteria,2KV6A@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the pseudouridine synthase RsuA family	rsuA	-	5.4.99.19	ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_1649426_2	159087.Daro_0015	1.52e-83	249.0	2ADKK@1|root,313B9@2|Bacteria,1RKP2@1224|Proteobacteria,2VSDK@28216|Betaproteobacteria,2KWK9@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of unknown function (DUF1857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1857
k59_1239587_1	1537917.JU82_05115	2.15e-83	261.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,42NBJ@68525|delta/epsilon subdivisions,2YMTY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Mg chelatase-related protein	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
k59_1649438_1	929558.SMGD1_2842	1.15e-139	407.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,42UPM@68525|delta/epsilon subdivisions,2YRIE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL
k59_828164_1	159087.Daro_3627	9.19e-199	551.0	COG3954@1|root,COG3954@2|Bacteria,1MWN9@1224|Proteobacteria,2VHZD@28216|Betaproteobacteria,2KV0P@206389|Rhodocyclales	206389|Rhodocyclales	C	Phosphoribulokinase	-	-	2.7.1.19	ko:K00855	ko00710,ko01100,ko01120,ko01200,map00710,map01100,map01120,map01200	M00165,M00166	R01523	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK
k59_1414917_1	387093.SUN_2238	6.34e-54	189.0	COG1080@1|root,COG1925@1|root,COG1080@2|Bacteria,COG1925@2|Bacteria,1MUT8@1224|Proteobacteria,42P77@68525|delta/epsilon subdivisions	1224|Proteobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	-	-	2.7.1.202,2.7.3.9	ko:K02768,ko:K08483,ko:K11183	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1,8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PTS-HPr,PTS_EIIA_2
k59_1473329_1	1502770.JQMG01000001_gene2228	4.85e-79	239.0	COG0546@1|root,COG0546@2|Bacteria,1RCXJ@1224|Proteobacteria,2VS13@28216|Betaproteobacteria,2KMBK@206350|Nitrosomonadales	206350|Nitrosomonadales	S	subfamily IA, variant 1	-	-	3.1.3.105	ko:K22292	ko00520,map00520	-	R11785	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_1473329_2	666681.M301_0956	2.6e-25	100.0	COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,2VHGP@28216|Betaproteobacteria,2KKJS@206350|Nitrosomonadales	206350|Nitrosomonadales	H	O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway	ubiG	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_23
k59_1473332_1	1537917.JU82_04930	1.29e-75	232.0	COG2048@1|root,COG2048@2|Bacteria,1RFWK@1224|Proteobacteria,43B86@68525|delta/epsilon subdivisions,2YT6P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Heterodisulfide reductase subunit B	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	CCG
k59_1826843_1	1249480.B649_06820	2.3e-116	342.0	COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,42QJ2@68525|delta/epsilon subdivisions,2YNBV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COGs COG3864 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
k59_298455_1	709032.Sulku_2335	7.9e-52	170.0	COG3907@1|root,COG3907@2|Bacteria,1MY7B@1224|Proteobacteria,42RAC@68525|delta/epsilon subdivisions,2YQ1I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COGs COG3907 PAP2 (acid phosphatase) superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
k59_298455_2	1537917.JU82_02020	1.69e-40	146.0	COG2194@1|root,COG2194@2|Bacteria,1MWS7@1224|Proteobacteria,42MI1@68525|delta/epsilon subdivisions,2YMPQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Sulfatase	eptA	-	2.7.8.43	ko:K03760	ko01503,map01503	M00722	R11555,R11556,R11557	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DUF1705,Sulfatase
k59_1296958_1	522306.CAP2UW1_2602	1.9e-23	106.0	COG2202@1|root,COG2703@1|root,COG3437@1|root,COG4251@1|root,COG2202@2|Bacteria,COG2703@2|Bacteria,COG3437@2|Bacteria,COG4251@2|Bacteria,1NWNJ@1224|Proteobacteria,2WHVM@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Pfam Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	PAS,Response_reg
k59_123489_1	1300005.R9RGE0_9CAUD	2.08e-89	286.0	4QGA5@10239|Viruses,4QURD@35237|dsDNA viruses  no RNA stage,4QT9N@28883|Caudovirales,4QP47@10744|Podoviridae	10744|Podoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_475924_1	159087.Daro_0527	1.3e-117	352.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,2VHI9@28216|Betaproteobacteria,2KUN3@206389|Rhodocyclales	206389|Rhodocyclales	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_4,Toprim_N,zf-CHC2
k59_475924_2	159087.Daro_0528	0.000405	41.2	COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,2VR35@28216|Betaproteobacteria,2KWI1@206389|Rhodocyclales	206389|Rhodocyclales	S	Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
k59_1473366_1	709032.Sulku_1486	4.37e-78	244.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,42M4X@68525|delta/epsilon subdivisions,2YMCF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
k59_123498_1	1123518.ARWI01000001_gene1861	1.56e-99	304.0	COG0342@1|root,COG0342@2|Bacteria,1MVFS@1224|Proteobacteria,1RYCF@1236|Gammaproteobacteria,461NY@72273|Thiotrichales	72273|Thiotrichales	U	glutamate--cysteine ligase	-	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	GshA
k59_123498_2	517418.Ctha_0428	3.23e-16	79.7	COG3004@1|root,COG3004@2|Bacteria,1FDWE@1090|Chlorobi	1090|Chlorobi	P	) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
k59_1708170_1	1165841.SULAR_04222	3.02e-86	258.0	COG0546@1|root,COG0546@2|Bacteria,1NDKE@1224|Proteobacteria,42SW4@68525|delta/epsilon subdivisions,2YPI4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	HAD-superfamily hydrolase, subfamily IA, variant 1	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_1708170_2	1165841.SULAR_04212	6.41e-28	107.0	COG2733@1|root,COG2733@2|Bacteria,1R4JT@1224|Proteobacteria,42RK1@68525|delta/epsilon subdivisions,2YPBZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_123500_1	1249480.B649_02810	2.28e-29	112.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,42MDN@68525|delta/epsilon subdivisions,2YMPS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k59_123500_2	709032.Sulku_0562	2.89e-73	222.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,42SDX@68525|delta/epsilon subdivisions,2YP47@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
k59_1766885_1	722419.PH505_af00170	3.79e-176	508.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,1RNQS@1236|Gammaproteobacteria,2Q0PA@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	K	Participates in both transcription termination and antitermination	nusA	GO:0001000,GO:0001121,GO:0001125,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
k59_1826892_1	159087.Daro_3347	1.59e-19	86.3	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,2WEJI@28216|Betaproteobacteria,2KUP5@206389|Rhodocyclales	206389|Rhodocyclales	P	Ion channel	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_N
k59_1826892_2	159087.Daro_3348	1.04e-76	233.0	2D2K4@1|root,32TD0@2|Bacteria,1MZKF@1224|Proteobacteria,2VUUX@28216|Betaproteobacteria,2KZ3H@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF3124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3124
k59_1826892_3	159087.Daro_3904	3.34e-45	162.0	COG0659@1|root,COG0664@1|root,COG0659@2|Bacteria,COG0664@2|Bacteria,1MVWV@1224|Proteobacteria,2VN25@28216|Betaproteobacteria,2KXUF@206389|Rhodocyclales	206389|Rhodocyclales	P	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp,cNMP_binding
k59_1766890_1	563040.Saut_1022	2.16e-29	114.0	COG2041@1|root,COG2041@2|Bacteria,1MX9E@1224|Proteobacteria,42QKD@68525|delta/epsilon subdivisions,2YNHF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Sulfite dehydrogenase (Cytochrome) subunit SorA apoprotein	sorA	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Mo-co_dimer,Oxidored_molyb
k59_1766890_2	387093.SUN_1103	7.57e-38	129.0	COG2010@1|root,COG2010@2|Bacteria,1NJ3U@1224|Proteobacteria,42W80@68525|delta/epsilon subdivisions,2YQGQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	cytochrome C oxidoreductase subunit B	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1355600_1	264730.PSPPH_4593	3.77e-53	169.0	COG0051@1|root,COG0051@2|Bacteria,1RGWF@1224|Proteobacteria,1S3QX@1236|Gammaproteobacteria,1Z7RQ@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0001072,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0015935,GO:0019219,GO:0019222,GO:0019538,GO:0022626,GO:0022627,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2001141	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
k59_1533253_1	697282.Mettu_2058	1.44e-111	352.0	COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XDYH@135618|Methylococcales	135618|Methylococcales	T	Diguanylate cyclase phosphodiesterase with PAS PAC	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GGDEF
k59_1473389_2	1121937.AUHJ01000013_gene836	1.2e-13	69.3	COG2200@1|root,COG2200@2|Bacteria,1MVJY@1224|Proteobacteria,1RPDW@1236|Gammaproteobacteria,466J8@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	COG2200 FOG EAL domain	ycgF	-	-	ko:K21973	-	-	-	-	ko00000	-	-	-	EAL
k59_1121839_1	90814.KL370891_gene1383	4.08e-38	144.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,4609X@72273|Thiotrichales	72273|Thiotrichales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4
k59_535444_1	709032.Sulku_2480	2.25e-121	356.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,42N75@68525|delta/epsilon subdivisions,2YNFC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Metallophosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
k59_1004518_1	358220.C380_06130	1.6e-130	379.0	28HKD@1|root,2Z7V8@2|Bacteria,1MXBM@1224|Proteobacteria,2VJ6Q@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Type II restriction enzyme	-	-	3.1.21.4	ko:K01155	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	-
k59_886397_1	1249480.B649_08990	9.34e-48	161.0	COG3218@1|root,COG3218@2|Bacteria,1NNSH@1224|Proteobacteria,42X3M@68525|delta/epsilon subdivisions,2YQQ8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	transport system auxiliary component	-	-	-	ko:K18480	-	M00669	-	-	ko00000,ko00002,ko02000	3.A.1.27.1	-	-	ABC_trans_aux
k59_886397_2	357804.Ping_1679	1.86e-49	174.0	COG1463@1|root,COG1463@2|Bacteria,1MU4B@1224|Proteobacteria,1S5E8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	ABC-type transport system involved in resistance to organic solvents periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
k59_886397_3	709032.Sulku_1878	5.58e-30	113.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,42NTG@68525|delta/epsilon subdivisions,2YNB7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	abc transporter atp-binding protein	iamA	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
k59_64013_1	292415.Tbd_1581	9.43e-101	305.0	COG0845@1|root,COG0845@2|Bacteria,1PJHF@1224|Proteobacteria,2VIRN@28216|Betaproteobacteria,1KSR8@119069|Hydrogenophilales	119069|Hydrogenophilales	M	HlyD family secretion protein	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_3
k59_592950_2	1165841.SULAR_05173	2.7e-163	476.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,42NDS@68525|delta/epsilon subdivisions,2YN0K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	DNA recombination protein	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
k59_768067_1	1304883.KI912532_gene3071	4.32e-33	120.0	COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,2VHPY@28216|Betaproteobacteria,2KUD3@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
k59_768067_2	557598.LHK_00363	5.99e-72	217.0	COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,2VR2S@28216|Betaproteobacteria,2KR2V@206351|Neisseriales	206351|Neisseriales	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
k59_768067_3	395494.Galf_2268	1.3e-25	101.0	COG1469@1|root,COG1469@2|Bacteria,1MV1B@1224|Proteobacteria,2VIC9@28216|Betaproteobacteria,44V3J@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Type I GTP cyclohydrolase folE2	folE2	-	3.5.4.16	ko:K09007	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GCHY-1
k59_1533314_1	1304883.KI912532_gene1561	3.59e-29	110.0	COG1651@1|root,COG1651@2|Bacteria,1RD39@1224|Proteobacteria,2VIHV@28216|Betaproteobacteria,2KW1Z@206389|Rhodocyclales	206389|Rhodocyclales	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	dsbC	-	5.3.4.1	ko:K03981	-	-	-	-	ko00000,ko01000,ko02044,ko03110	3.A.7.11.1	-	-	DsbC_N,Thioredoxin_2
k59_1533314_2	159087.Daro_3510	5.71e-40	142.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,2VIPS@28216|Betaproteobacteria,2KUAJ@206389|Rhodocyclales	206389|Rhodocyclales	C	Ubiquinone biosynthesis hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,FAD_binding_3,SE
k59_1533316_1	1168067.JAGP01000001_gene424	1.35e-90	286.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,1RN6Z@1236|Gammaproteobacteria,4602V@72273|Thiotrichales	72273|Thiotrichales	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
k59_1535047_1	1249480.B649_02525	2.63e-51	169.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,42RGS@68525|delta/epsilon subdivisions,2YNY5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_N
k59_1535047_2	1537917.JU82_11770	5.71e-92	270.0	COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,42SJ8@68525|delta/epsilon subdivisions,2YNWU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
k59_1063830_1	709032.Sulku_1079	3.91e-24	102.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,42PV9@68525|delta/epsilon subdivisions,2YMKD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
k59_1063830_2	709032.Sulku_1077	2.39e-53	171.0	COG1514@1|root,COG1514@2|Bacteria,1Q2AV@1224|Proteobacteria,42VB6@68525|delta/epsilon subdivisions,2YQIV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	2'-5' RNA ligase	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
k59_125537_1	159087.Daro_3735	3.6e-82	257.0	COG4262@1|root,COG4262@2|Bacteria,1QTYC@1224|Proteobacteria,2VK9Z@28216|Betaproteobacteria,2KVY0@206389|Rhodocyclales	206389|Rhodocyclales	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
k59_125538_2	323848.Nmul_A0855	2.29e-16	78.2	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VI6G@28216|Betaproteobacteria,371UM@32003|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	odhL	GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
k59_1006528_2	696747.NIES39_D04330	1.09e-40	155.0	COG0517@1|root,COG0642@1|root,COG0745@1|root,COG2202@1|root,COG2203@1|root,COG3829@1|root,COG0517@2|Bacteria,COG0745@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,1G09B@1117|Cyanobacteria,1H71H@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
k59_1080299_3	1172190.M947_02935	2.7e-20	85.1	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,42V4I@68525|delta/epsilon subdivisions,2YQ1K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
k59_1846864_1	709032.Sulku_1233	2.17e-154	449.0	COG1166@1|root,COG1166@2|Bacteria,1MU80@1224|Proteobacteria,42M2B@68525|delta/epsilon subdivisions,2YMP0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	arginine decarboxylase	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0422	Orn_Arg_deC_N
k59_494784_1	1249480.B649_00375	1.69e-73	227.0	2A50M@1|root,30TNT@2|Bacteria,1PDM4@1224|Proteobacteria,42QJ6@68525|delta/epsilon subdivisions,2YPYD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	AMIN domain	-	-	-	-	-	-	-	-	-	-	-	-	AMIN
k59_494784_2	709032.Sulku_0045	4.03e-11	58.9	2BRG4@1|root,32MA7@2|Bacteria,1Q36H@1224|Proteobacteria,42WUT@68525|delta/epsilon subdivisions,2YQQJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_372469_1	1537917.JU82_06005	1.44e-142	426.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,42MMV@68525|delta/epsilon subdivisions,2YMV9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k59_77681_1	1537917.JU82_10060	1.68e-73	247.0	COG2911@1|root,COG2911@2|Bacteria,1PBYT@1224|Proteobacteria,42T65@68525|delta/epsilon subdivisions,2YPPD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
k59_143143_1	1537917.JU82_02705	3.69e-93	287.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,42M3N@68525|delta/epsilon subdivisions,2YMQ3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
k59_494819_1	709032.Sulku_1311	4.34e-90	266.0	COG2077@1|root,COG2077@2|Bacteria,1Q5WV@1224|Proteobacteria,431ZJ@68525|delta/epsilon subdivisions,2YSAN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	AhpC/TSA family	-	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	Redoxin
k59_143154_1	1051501.AYTL01000030_gene3032	2.95e-05	46.2	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1TQ2X@1239|Firmicutes,4HA6T@91061|Bacilli,1ZCE7@1386|Bacillus	91061|Bacilli	T	COG2199 FOG GGDEF domain	ytrP	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,GGDEF
k59_143154_2	1249480.B649_02120	1.28e-93	295.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2YMW4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_611320_1	709032.Sulku_0756	4.97e-32	116.0	COG0712@1|root,COG0712@2|Bacteria,1RFPY@1224|Proteobacteria,42SKR@68525|delta/epsilon subdivisions,2YPHX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
k59_611320_2	709032.Sulku_0755	8.12e-53	170.0	COG0711@1|root,COG0711@2|Bacteria,1Q9TP@1224|Proteobacteria,42U87@68525|delta/epsilon subdivisions,2YPT1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
k59_721419_1	1249480.B649_04140	0.000116	47.0	COG1580@1|root,COG1580@2|Bacteria,1NBUX@1224|Proteobacteria,42RSV@68525|delta/epsilon subdivisions,2YPAW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Controls the rotational direction of flagella during chemotaxis	fliL	-	-	ko:K02415	-	-	-	-	ko00000,ko02035	-	-	-	FliL
k59_1846924_1	1537917.JU82_04470	1.6e-71	222.0	COG2833@1|root,COG2833@2|Bacteria,1MW0V@1224|Proteobacteria,42KZ6@68525|delta/epsilon subdivisions,2YMPZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	hmm pf04305	-	-	-	-	-	-	-	-	-	-	-	-	DUF455
k59_494837_2	596320.NEIFL0001_0118	8.8e-60	199.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,2VI5Q@28216|Betaproteobacteria,2KPIJ@206351|Neisseriales	206351|Neisseriales	D	Peptidoglycan polymerase that is essential for cell division	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
k59_1026508_1	709032.Sulku_1293	6.49e-116	338.0	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,42PH4@68525|delta/epsilon subdivisions,2YMRW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	mechanosensitive ion channel	-	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
k59_1026508_2	1123242.JH636435_gene1034	5.07e-30	112.0	2E3Q3@1|root,32YN2@2|Bacteria,2J0W4@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_721429_1	207559.Dde_2343	2.38e-14	77.4	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,42MIH@68525|delta/epsilon subdivisions,2WK3V@28221|Deltaproteobacteria,2M97X@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Metal-dependent hydrolase HDOD	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
k59_1141313_1	1537917.JU82_04495	6.45e-76	239.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,42M48@68525|delta/epsilon subdivisions,2YMM2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
k59_1141313_2	1537917.JU82_04500	2.11e-29	108.0	COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,42MEH@68525|delta/epsilon subdivisions,2YMFC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
k59_1607064_1	1123367.C666_17230	3.72e-19	87.8	COG5126@1|root,COG5126@2|Bacteria,1RKQX@1224|Proteobacteria,2VT6J@28216|Betaproteobacteria,2KWRW@206389|Rhodocyclales	206389|Rhodocyclales	DTZ	EF-hand domain pair	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5,EF-hand_7
k59_846089_1	748247.AZKH_2522	9.66e-110	319.0	COG1335@1|root,COG1335@2|Bacteria,1MU5N@1224|Proteobacteria,2VJFI@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	isochorismatase hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
k59_197729_1	159087.Daro_2373	4.48e-49	157.0	COG0236@1|root,COG0236@2|Bacteria,1NEMA@1224|Proteobacteria,2VW0X@28216|Betaproteobacteria,2KXFD@206389|Rhodocyclales	206389|Rhodocyclales	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
k59_197729_2	159087.Daro_2372	2.23e-21	92.4	COG0842@1|root,COG0842@2|Bacteria,1R94U@1224|Proteobacteria,2VM36@28216|Betaproteobacteria,2KW7K@206389|Rhodocyclales	206389|Rhodocyclales	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
k59_312647_1	395494.Galf_2569	5.21e-73	231.0	COG3287@1|root,COG3287@2|Bacteria,1QUQH@1224|Proteobacteria,2VMN2@28216|Betaproteobacteria,44WBJ@713636|Nitrosomonadales	28216|Betaproteobacteria	S	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
k59_143183_1	1165841.SULAR_07750	2.56e-67	210.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,42MWA@68525|delta/epsilon subdivisions,2YMQ7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
k59_143183_2	1165841.SULAR_07755	3.34e-94	281.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,42MWK@68525|delta/epsilon subdivisions,2YMIH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
k59_77718_1	1349767.GJA_4621	2.71e-152	442.0	COG1785@1|root,COG1785@2|Bacteria,1MXI2@1224|Proteobacteria,2VKXB@28216|Betaproteobacteria,4737F@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	Alkaline phosphatase homologues	phoA2	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
k59_1310573_1	1172190.M947_03675	1.76e-08	62.0	2AJ4C@1|root,319NV@2|Bacteria,1Q3D8@1224|Proteobacteria,431S6@68525|delta/epsilon subdivisions,2YS5U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_494861_1	709032.Sulku_0423	2.39e-78	241.0	COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,42NWB@68525|delta/epsilon subdivisions,2YP3D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
k59_372537_1	1537917.JU82_02965	7.99e-59	188.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,42MWK@68525|delta/epsilon subdivisions,2YMIH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
k59_372537_2	1537917.JU82_02960	1.22e-177	496.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,42MWA@68525|delta/epsilon subdivisions,2YMQ7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
k59_372537_3	709032.Sulku_0005	1.33e-89	262.0	COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,42RDZ@68525|delta/epsilon subdivisions,2YP5I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
k59_372537_4	1249480.B649_00020	7.48e-143	417.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1RGCV@1224|Proteobacteria,42M47@68525|delta/epsilon subdivisions,2YMRS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	(EAL) domain protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_1490462_1	1537917.JU82_08440	2.2e-119	357.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,42M4S@68525|delta/epsilon subdivisions,2YM8Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	-	-	1.12.5.1	ko:K05922	-	-	-	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
k59_312681_1	1249480.B649_03235	1e-67	209.0	COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,42RMF@68525|delta/epsilon subdivisions,2YPMK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	pgpA	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
k59_963723_1	1249480.B649_09050	9.98e-131	395.0	COG0457@1|root,COG0457@2|Bacteria,1QV15@1224|Proteobacteria,42NKI@68525|delta/epsilon subdivisions,2YMKG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	COG0457 FOG TPR repeat	pflB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_6,TPR_8
k59_1195988_1	686340.Metal_3870	1.58e-138	410.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,1RN05@1236|Gammaproteobacteria,1XEP5@135618|Methylococcales	135618|Methylococcales	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_197818_1	1123326.JFBL01000002_gene1601	3.48e-19	91.7	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,43AX6@68525|delta/epsilon subdivisions,2YR51@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Double sensory domain of two-component sensor kinase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_3
k59_963748_1	666681.M301_0309	5.84e-78	233.0	COG0139@1|root,COG0139@2|Bacteria,1MW67@1224|Proteobacteria,2VR9B@28216|Betaproteobacteria,2KMS4@206350|Nitrosomonadales	206350|Nitrosomonadales	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19	ko:K01496	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04037	RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH
k59_963748_2	1502770.JQMG01000001_gene1129	3.66e-28	103.0	COG0140@1|root,COG0140@2|Bacteria,1MZEE@1224|Proteobacteria,2VUN8@28216|Betaproteobacteria,2KMX7@206350|Nitrosomonadales	206350|Nitrosomonadales	E	PFAM phosphoribosyl-ATP pyrophosphohydrolase	hisE	-	3.6.1.31	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-PH
k59_1847033_1	1537917.JU82_03180	1.04e-116	348.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,42MS8@68525|delta/epsilon subdivisions,2YMUQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
k59_1372805_1	709032.Sulku_2489	2.94e-178	505.0	COG3474@1|root,COG3474@2|Bacteria,1R1KB@1224|Proteobacteria,42Z1J@68525|delta/epsilon subdivisions,2YRH9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome c-552 DMSO reductase-like, heme-binding domain	-	-	-	ko:K17052	-	-	-	-	ko00000,ko02000	5.A.3.8	-	-	Cytochrom_C,EB_dh
k59_21380_1	1249480.B649_06140	7.17e-104	331.0	COG2982@1|root,COG2982@2|Bacteria,1QA6E@1224|Proteobacteria,42NCN@68525|delta/epsilon subdivisions,2YM89@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_1,DUF3971
k59_143270_1	709032.Sulku_0409	2.05e-81	260.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1NQKX@1224|Proteobacteria,43CB3@68525|delta/epsilon subdivisions,2YTAN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG2200 FOG EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,sCache_2
k59_902959_1	598659.NAMH_1612	8.92e-71	228.0	COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,42MX8@68525|delta/epsilon subdivisions,2YN00@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	flaB	GO:0001539,GO:0005575,GO:0005576,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_IN,Flagellin_N
k59_372580_1	1537917.JU82_04890	5.63e-35	122.0	2BSRI@1|root,32MUE@2|Bacteria,1Q3E8@1224|Proteobacteria,42X6B@68525|delta/epsilon subdivisions,2YQST@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_372580_2	1537917.JU82_04895	5.54e-97	293.0	COG1193@1|root,COG1193@2|Bacteria,1QUJI@1224|Proteobacteria,42P7P@68525|delta/epsilon subdivisions,2YMFB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	GO:0000018,GO:0008150,GO:0009892,GO:0010605,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0080090	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
k59_846164_2	709032.Sulku_1010	1.45e-117	345.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,42MW5@68525|delta/epsilon subdivisions,2YN4M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0283	DHQ_synthase
k59_312720_1	205922.Pfl01_0174	1.44e-06	53.5	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,1RN5K@1236|Gammaproteobacteria,1YRZ2@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	MU	Transporter	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_312720_2	648757.Rvan_0569	7.28e-23	98.6	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,3N80J@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	mdtB	-	-	ko:K03296,ko:K07788,ko:K07789	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	2.A.6.2	-	-	ACR_tran
k59_1310673_1	1249480.B649_01155	4.87e-118	347.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,42M9G@68525|delta/epsilon subdivisions,2YMSC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
k59_963797_1	1236976.JCM16418_317	1.1e-22	101.0	COG1020@1|root,COG3321@1|root,COG1020@2|Bacteria,COG3321@2|Bacteria,1TPTH@1239|Firmicutes,4HAHU@91061|Bacilli,26Q93@186822|Paenibacillaceae	91061|Bacilli	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,ketoacyl-synt
k59_257524_1	1168034.FH5T_10755	1.7e-79	261.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,2FMPX@200643|Bacteroidia	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k59_1310692_1	316407.85675271	1.76e-40	146.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RPT8@1236|Gammaproteobacteria,3XNEX@561|Escherichia	1236|Gammaproteobacteria	K	DNA-binding transcription factor activity	yeiE	GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_1847099_1	666681.M301_1923	2.6e-67	212.0	COG3047@1|root,COG3047@2|Bacteria,1NUZJ@1224|Proteobacteria,2VR6Y@28216|Betaproteobacteria,2KKCV@206350|Nitrosomonadales	206350|Nitrosomonadales	M	PFAM OmpW family	-	-	-	ko:K07275	-	-	-	-	ko00000	-	-	-	OmpW
k59_1666746_1	1537917.JU82_04635	2.07e-101	307.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,42MVX@68525|delta/epsilon subdivisions,2YMSF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	iIT341.HP1134	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_1607202_1	1249480.B649_01405	1.09e-70	216.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,42SJW@68525|delta/epsilon subdivisions,2YNXS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	sigma 54 modulation protein ribosomal protein S30EA	raiA	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
k59_903025_2	709032.Sulku_0678	1.51e-98	288.0	COG0782@1|root,COG0782@2|Bacteria,1RAP0@1224|Proteobacteria,42UCT@68525|delta/epsilon subdivisions,2YRMZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	-	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
k59_903025_3	709032.Sulku_0679	1.19e-12	65.5	COG0071@1|root,COG0071@2|Bacteria,1NCY0@1224|Proteobacteria	1224|Proteobacteria	O	Belongs to the small heat shock protein (HSP20) family	hspC1	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
k59_1372877_1	1123514.KB905899_gene865	4.9e-228	644.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,1RMY6@1236|Gammaproteobacteria,46020@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
k59_1372877_2	85643.Tmz1t_3198	9.64e-07	53.5	COG1629@1|root,COG4771@2|Bacteria,1MW7D@1224|Proteobacteria,2VIV2@28216|Betaproteobacteria,2KVXE@206389|Rhodocyclales	206389|Rhodocyclales	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_611565_1	640081.Dsui_1306	4.25e-49	165.0	COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,2VHC6@28216|Betaproteobacteria,2KVZB@206389|Rhodocyclales	206389|Rhodocyclales	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
k59_611565_2	159087.Daro_0627	1.49e-98	289.0	COG1309@1|root,COG1309@2|Bacteria,1MWF7@1224|Proteobacteria,2VQ4C@28216|Betaproteobacteria,2KYC0@206389|Rhodocyclales	206389|Rhodocyclales	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K05501	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	TetR_N
k59_903027_2	666681.M301_0118	1.77e-17	77.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,2VSRT@28216|Betaproteobacteria,2KMM1@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
k59_611568_1	1211579.PP4_35680	5.07e-44	153.0	COG0406@1|root,COG0406@2|Bacteria,1R62X@1224|Proteobacteria	1224|Proteobacteria	G	phosphoglycerate mutase	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
k59_1783362_1	323850.Shew_1858	3.39e-84	260.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,1S5KR@1236|Gammaproteobacteria,2QA4J@267890|Shewanellaceae	1236|Gammaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0016051,GO:0043170,GO:0044238,GO:0071704,GO:1901576	2.6.1.109	ko:K19715	-	-	R11395	RC00160	ko00000,ko01000,ko01005	-	-	-	DegT_DnrJ_EryC1
k59_1435908_1	641143.HMPREF9331_00576	5.84e-47	164.0	COG0438@1|root,COG0438@2|Bacteria,4NJZD@976|Bacteroidetes,1IEM7@117743|Flavobacteriia,1EQP4@1016|Capnocytophaga	976|Bacteroidetes	M	overlaps another CDS with the same product name	-	-	2.4.1.348	ko:K12995	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
k59_1553570_1	709032.Sulku_0329	9.15e-64	207.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,43BKD@68525|delta/epsilon subdivisions,2YNJC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_1553570_2	1537917.JU82_03810	1.11e-27	110.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,42MB1@68525|delta/epsilon subdivisions,2YMVC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
k59_372656_1	1165841.SULAR_03587	1.09e-63	218.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2YNQF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0474 Cation transport ATPase	-	-	-	-	-	-	-	-	-	-	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
k59_1849734_2	1304883.KI912532_gene610	1.2e-148	431.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,2VI3N@28216|Betaproteobacteria,2KU6W@206389|Rhodocyclales	206389|Rhodocyclales	J	ribonuclease, Rne Rng family	cafA	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G
k59_1029668_2	1537917.JU82_06635	2.39e-32	117.0	COG0621@1|root,COG0621@2|Bacteria,1MUCS@1224|Proteobacteria,42MN1@68525|delta/epsilon subdivisions,2YN0D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	MiaB-like tRNA modifying enzyme	yqeV	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,UPF0004
k59_314274_1	929558.SMGD1_2862	2.34e-31	123.0	COG4774@1|root,COG4774@2|Bacteria,1QV5G@1224|Proteobacteria	1224|Proteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_314274_2	387093.SUN_0470	9.2e-92	274.0	COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,42N54@68525|delta/epsilon subdivisions,2YNS5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
k59_79673_1	709032.Sulku_1558	1.5e-167	474.0	COG2301@1|root,COG2301@2|Bacteria,1NUDQ@1224|Proteobacteria,42QUW@68525|delta/epsilon subdivisions,2YNZV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the HpcH HpaI aldolase family	citE	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
k59_1785410_2	1537917.JU82_01850	7.71e-52	171.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,42P3I@68525|delta/epsilon subdivisions,2YMYB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
k59_1668763_1	1537917.JU82_09795	1.35e-100	305.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,42N30@68525|delta/epsilon subdivisions,2YMCR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
k59_905036_1	1085623.GNIT_3554	1.18e-48	166.0	2910Q@1|root,2ZNNC@2|Bacteria,1PCP3@1224|Proteobacteria,1S0BX@1236|Gammaproteobacteria,46AYG@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_614349_1	1280944.HY17_04940	1.07e-69	234.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2TRZD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
k59_676047_1	1249480.B649_11085	1.18e-107	337.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,42NKH@68525|delta/epsilon subdivisions,2YMVS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the helicase family. UvrD subfamily	addA	-	3.1.11.5	ko:K03582	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C
k59_497369_1	323850.Shew_1412	4.78e-121	358.0	COG0457@1|root,COG0457@2|Bacteria,1QVTD@1224|Proteobacteria,1RSNS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Glycosyltransferase WbsX	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_WbsX
k59_1438693_1	709032.Sulku_1629	4.16e-14	75.1	COG2199@1|root,COG2200@1|root,COG2200@2|Bacteria,COG3706@2|Bacteria,1Q49C@1224|Proteobacteria,42MW2@68525|delta/epsilon subdivisions,2YNR7@29547|Epsilonproteobacteria	2|Bacteria	T	PFAM EAL domain	adiA	-	2.7.7.65,4.1.1.19	ko:K01584,ko:K20955,ko:K21025	ko00330,ko01100,ko02025,ko05111,map00330,map01100,map02025,map05111	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	EAL,GGDEF,HATPase_c,HisKA,OKR_DC_1,OKR_DC_1_C,OKR_DC_1_N,Response_reg
k59_434840_1	1122611.KB903964_gene4905	5.54e-22	97.8	COG0491@1|root,COG0491@2|Bacteria,2HFVZ@201174|Actinobacteria,4EFG8@85012|Streptosporangiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	ko:K05555	ko01057,ko01130,map01057,map01130	M00778	R09305	-	ko00000,ko00001,ko00002,ko01000,ko01008	-	-	-	Lactamase_B
k59_1609295_1	1168067.JAGP01000001_gene1070	2.67e-100	298.0	COG0637@1|root,COG0637@2|Bacteria,1PUMZ@1224|Proteobacteria,1RPII@1236|Gammaproteobacteria,46091@72273|Thiotrichales	72273|Thiotrichales	S	PFAM Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
k59_497381_1	709032.Sulku_0338	1.74e-35	123.0	COG0636@1|root,COG0636@2|Bacteria,1NAIE@1224|Proteobacteria,42VAI@68525|delta/epsilon subdivisions,2YPYI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
k59_1749234_1	159087.Daro_1018	6.94e-149	438.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,2VJUZ@28216|Betaproteobacteria,2KVFW@206389|Rhodocyclales	206389|Rhodocyclales	EQ	Hydantoinase/oxoprolinase N-terminal region	acxA	-	6.4.1.6	ko:K10855	-	-	-	-	ko00000,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
k59_1687907_1	317025.Tcr_0603	3.6e-63	197.0	COG5501@1|root,COG5501@2|Bacteria,1RH4J@1224|Proteobacteria,1S4ZT@1236|Gammaproteobacteria,461A3@72273|Thiotrichales	72273|Thiotrichales	S	Sulfur oxidation protein SoxY	-	-	-	ko:K17226	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxY,TAT_signal
k59_1687907_2	90814.KL370891_gene1519	4.66e-13	65.1	COG2010@1|root,COG2010@2|Bacteria,1N91W@1224|Proteobacteria,1SD5N@1236|Gammaproteobacteria,461B4@72273|Thiotrichales	72273|Thiotrichales	C	Cytochrome c	-	-	-	ko:K17223	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C,Cytochrome_CBB3
k59_1052681_1	1249480.B649_07340	3.64e-88	280.0	COG5001@1|root,COG5001@2|Bacteria,1R4H0@1224|Proteobacteria	1224|Proteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_1052681_2	1249480.B649_07335	2.16e-44	155.0	COG3400@1|root,COG3400@2|Bacteria,1N5T1@1224|Proteobacteria,42M0B@68525|delta/epsilon subdivisions,2YMCG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	domain protein	-	-	-	ko:K09944	-	-	-	-	ko00000	-	-	-	TrkA_C
k59_1218913_1	1165841.SULAR_05233	4.55e-76	234.0	COG2204@1|root,COG2204@2|Bacteria,1QASN@1224|Proteobacteria,42RV2@68525|delta/epsilon subdivisions,2YP76@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activ_2,Sigma54_activat
k59_1334923_1	1121861.KB899915_gene1863	3.74e-16	80.1	28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,2TVGJ@28211|Alphaproteobacteria,2JPR0@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1284685_1	709032.Sulku_0147	2.72e-52	169.0	COG0300@1|root,COG0300@2|Bacteria,1RAFB@1224|Proteobacteria,42RPR@68525|delta/epsilon subdivisions,2YPAJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_1284685_2	1548153.LR59_09525	8.89e-12	68.6	COG1345@1|root,COG1345@2|Bacteria,1MUVP@1224|Proteobacteria,42MHW@68525|delta/epsilon subdivisions,2YNJG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	fliD	GO:0001539,GO:0005575,GO:0005576,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_IN,FliD_C,FliD_N
k59_1749245_1	1123393.KB891333_gene2577	1.53e-71	222.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,2VJ3S@28216|Betaproteobacteria,1KS53@119069|Hydrogenophilales	119069|Hydrogenophilales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_97888_1	1120965.AUBV01000017_gene132	3.27e-23	103.0	COG0642@1|root,COG2202@1|root,COG5002@1|root,COG0642@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,4NDXU@976|Bacteroidetes,47M3T@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_1334928_1	1537917.JU82_07085	1.54e-127	381.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2YMMU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_1460801_2	1249480.B649_09225	1.97e-51	164.0	COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,42TN3@68525|delta/epsilon subdivisions,2YPT8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
k59_517844_1	1165841.SULAR_02043	2.25e-40	147.0	COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,42PIT@68525|delta/epsilon subdivisions,2YTJQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
k59_97902_1	1537917.JU82_08345	2.48e-67	208.0	COG3018@1|root,COG3018@2|Bacteria,1RGG9@1224|Proteobacteria,42P0S@68525|delta/epsilon subdivisions,2YQJK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	(Lipo)protein	-	-	-	ko:K09860	-	-	-	-	ko00000	-	-	-	LPP20
k59_699204_1	667632.KB890164_gene2224	1.31e-69	236.0	COG2132@1|root,COG2132@2|Bacteria,1PM6Q@1224|Proteobacteria,2VKR2@28216|Betaproteobacteria,1K12M@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	TIG
k59_1395135_1	709032.Sulku_1217	1.04e-29	108.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,42SFB@68525|delta/epsilon subdivisions,2YPMF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	general secretion pathway protein G	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
k59_1395135_2	709032.Sulku_1216	1.06e-40	140.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02246,ko:K02247,ko:K02456,ko:K02457,ko:K02458,ko:K10924	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
k59_739954_1	159087.Daro_1077	7.43e-119	350.0	COG0477@1|root,COG2814@2|Bacteria,1PATR@1224|Proteobacteria,2WEDY@28216|Betaproteobacteria,2KZV7@206389|Rhodocyclales	206389|Rhodocyclales	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_392505_1	90813.JQMT01000001_gene1290	1.21e-71	230.0	COG1377@1|root,COG1377@2|Bacteria,1MUWI@1224|Proteobacteria,1RMHA@1236|Gammaproteobacteria,460BP@72273|Thiotrichales	72273|Thiotrichales	N	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhB	-	-	ko:K02401	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_2
k59_1804430_1	1537917.JU82_02690	7.96e-62	189.0	COG1145@1|root,COG1145@2|Bacteria,1QUJB@1224|Proteobacteria,42TSI@68525|delta/epsilon subdivisions,2YPU2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Ferredoxin	fdxA	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
k59_990931_1	1122236.KB905145_gene2484	6.46e-61	200.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,2VHQU@28216|Betaproteobacteria,2KKGG@206350|Nitrosomonadales	206350|Nitrosomonadales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_990931_2	1132855.KB913035_gene229	1.7e-57	182.0	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,2VSJV@28216|Betaproteobacteria,2KM92@206350|Nitrosomonadales	206350|Nitrosomonadales	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
k59_1630727_1	1165841.SULAR_09319	1.84e-29	111.0	COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,42QRU@68525|delta/epsilon subdivisions,2YMXG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	ABC transporter	-	-	-	ko:K15555,ko:K15578	ko00910,ko00920,ko02010,map00910,map00920,map02010	M00436,M00438	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.16.1,3.A.1.17.2	-	-	ABC_tran
k59_1630727_2	1165841.SULAR_09314	5.99e-106	311.0	COG0600@1|root,COG0600@2|Bacteria,1MU6Q@1224|Proteobacteria,42Q2R@68525|delta/epsilon subdivisions,2YNDK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0600 ABC-type nitrate sulfonate bicarbonate transport system permease component	-	-	-	ko:K15577	ko00910,ko02010,map00910,map02010	M00438	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16.1,3.A.1.16.2	-	-	BPD_transp_1
k59_1511967_1	1249480.B649_05770	9.27e-62	203.0	2AJGC@1|root,31A2T@2|Bacteria,1Q4TA@1224|Proteobacteria,42ZUH@68525|delta/epsilon subdivisions,2YRV9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1687986_2	1537917.JU82_01845	3.39e-132	378.0	COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,42MZF@68525|delta/epsilon subdivisions,2YMQX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
k59_1804444_1	1537917.JU82_03865	2.74e-136	407.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,42MTZ@68525|delta/epsilon subdivisions,2YMPF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
k59_1804462_1	1537917.JU82_07085	4.74e-39	144.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2YMMU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_1804462_2	1249480.B649_09060	1.01e-30	114.0	COG0688@1|root,COG0688@2|Bacteria,1P7K4@1224|Proteobacteria,42TG5@68525|delta/epsilon subdivisions,2YQHE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	phosphatidylserine decarboxylase	-	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
k59_1870887_1	709032.Sulku_1450	5.51e-74	226.0	2AI6H@1|root,318KU@2|Bacteria,1Q0KF@1224|Proteobacteria,42S88@68525|delta/epsilon subdivisions,2YP9S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_926822_1	1101190.ARWB01000001_gene2975	1.76e-44	152.0	COG2983@1|root,COG2983@2|Bacteria,1RHMX@1224|Proteobacteria,2U99S@28211|Alphaproteobacteria,36YGB@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Putative zinc- or iron-chelating domain	MA20_15575	-	-	ko:K09160	-	-	-	-	ko00000	-	-	-	CxxCxxCC
k59_926822_2	694430.Natoc_3214	1.04e-32	118.0	COG0225@1|root,arCOG02816@2157|Archaea,2XWKA@28890|Euryarchaeota,23V5S@183963|Halobacteria	183963|Halobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
k59_740022_1	1165841.SULAR_06188	5.57e-51	162.0	COG0636@1|root,COG0636@2|Bacteria,1NAIE@1224|Proteobacteria,42VAI@68525|delta/epsilon subdivisions,2YPYI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
k59_926826_1	742735.HMPREF9467_01660	2.59e-10	65.5	COG0463@1|root,COG0463@2|Bacteria,1V2EP@1239|Firmicutes,24GAY@186801|Clostridia,21YP3@1506553|Lachnoclostridium	186801|Clostridia	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_926828_1	640081.Dsui_0637	6.35e-61	193.0	COG0765@1|root,COG0765@2|Bacteria,1MV3I@1224|Proteobacteria,2VIQB@28216|Betaproteobacteria,2KW71@206389|Rhodocyclales	206389|Rhodocyclales	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10002	ko02010,ko02020,map02010,map02020	M00230	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.19,3.A.1.3.4	-	-	BPD_transp_1
k59_926828_2	640081.Dsui_0636	1.13e-32	119.0	COG0765@1|root,COG0765@2|Bacteria,1MUVX@1224|Proteobacteria,2VJ8A@28216|Betaproteobacteria,2KVZV@206389|Rhodocyclales	206389|Rhodocyclales	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10003	ko02010,ko02020,map02010,map02020	M00230	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.19,3.A.1.3.4	-	-	BPD_transp_1
k59_1749377_1	709032.Sulku_0279	1.82e-06	49.3	COG0457@1|root,COG0457@2|Bacteria,1QV1A@1224|Proteobacteria,42MIW@68525|delta/epsilon subdivisions,2YMDB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Paralysed flagella protein	pflA	-	-	-	-	-	-	-	-	-	-	-	TPR_21,TPR_6,TPR_8,YfiO
k59_1749377_2	1249480.B649_01220	1.9e-89	271.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,42M7V@68525|delta/epsilon subdivisions,2YMKI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
k59_1052866_1	330214.NIDE3512	4.53e-11	64.7	COG1858@1|root,COG1858@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	-	-	-	-	-	-	-	-	-	-	CCP_MauG,Cytochrom_C
k59_1460952_1	1249480.B649_06140	4.28e-41	153.0	COG2982@1|root,COG2982@2|Bacteria,1QA6E@1224|Proteobacteria,42NCN@68525|delta/epsilon subdivisions,2YM89@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_1,DUF3971
k59_1460952_2	1249480.B649_06135	2.91e-57	186.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,42MPA@68525|delta/epsilon subdivisions,2YMKT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
k59_517979_1	1304888.ATWF01000001_gene1470	1.1e-56	189.0	COG2203@1|root,COG3437@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,2GFDI@200930|Deferribacteres	2|Bacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3369,GAF,GAF_2,HD,PAS_3,PAS_9,Response_reg
k59_1460953_2	1537917.JU82_05620	2.54e-106	317.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,42M0T@68525|delta/epsilon subdivisions,2YMEX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0183	SHMT
k59_41378_1	580332.Slit_1692	5.67e-84	255.0	COG2175@1|root,COG2175@2|Bacteria,1R5KS@1224|Proteobacteria,2VIG6@28216|Betaproteobacteria,44W7U@713636|Nitrosomonadales	28216|Betaproteobacteria	Q	Taurine catabolism dioxygenase TauD, TfdA family	-	-	-	-	-	-	-	-	-	-	-	-	TauD
k59_454877_1	159087.Daro_0969	1.47e-45	151.0	COG3437@1|root,COG3437@2|Bacteria,1RDJ3@1224|Proteobacteria,2VR5G@28216|Betaproteobacteria,2KWE0@206389|Rhodocyclales	206389|Rhodocyclales	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_278564_1	159087.Daro_4112	5.66e-130	382.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,2VHQU@28216|Betaproteobacteria,2KV0S@206389|Rhodocyclales	206389|Rhodocyclales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_1512127_1	1537917.JU82_02875	2.17e-73	229.0	COG0348@1|root,COG0348@2|Bacteria,1Q4B9@1224|Proteobacteria,42P8A@68525|delta/epsilon subdivisions,2YNTH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_10,Fer4_5
k59_1512127_2	1537917.JU82_02870	2.12e-20	87.8	2ANXW@1|root,31DYS@2|Bacteria,1MYQS@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1512128_2	1249480.B649_01195	3.05e-57	178.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,42VAT@68525|delta/epsilon subdivisions,2YPSQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iIT341.HP1270	Oxidored_q2
k59_1512128_3	1537917.JU82_10925	1.09e-24	97.4	COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,42RES@68525|delta/epsilon subdivisions,2YP9Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
k59_1052908_2	317025.Tcr_0049	2.07e-139	404.0	COG0755@1|root,COG0755@2|Bacteria,1RG6M@1224|Proteobacteria,1RX07@1236|Gammaproteobacteria,45ZPJ@72273|Thiotrichales	72273|Thiotrichales	O	PFAM Cytochrome c assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
k59_1052914_1	1387312.BAUS01000002_gene1062	5.22e-48	172.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KMBP@206350|Nitrosomonadales	206350|Nitrosomonadales	T	PFAM EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_9
k59_278593_1	713587.THITH_14170	4.12e-69	214.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,1RQ38@1236|Gammaproteobacteria,1WW34@135613|Chromatiales	135613|Chromatiales	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
k59_1052926_1	1502770.JQMG01000001_gene577	1.75e-182	521.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,2VHKQ@28216|Betaproteobacteria,2KM0Z@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
k59_811287_1	159087.Daro_0559	1.56e-185	548.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,2VH3F@28216|Betaproteobacteria,2KUJ2@206389|Rhodocyclales	206389|Rhodocyclales	L	DNA polymerase III alpha subunit	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k59_1512185_2	1249480.B649_10855	7.77e-52	173.0	COG1426@1|root,COG1426@2|Bacteria,1Q33C@1224|Proteobacteria,42WQB@68525|delta/epsilon subdivisions,2YQFX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1284930_1	1205753.A989_18420	6.23e-07	51.2	COG0010@1|root,COG0010@2|Bacteria,1MY4S@1224|Proteobacteria,1S384@1236|Gammaproteobacteria,1X47S@135614|Xanthomonadales	135614|Xanthomonadales	E	Belongs to the arginase family	-	-	-	-	-	-	-	-	-	-	-	-	Arginase
k59_1284930_2	1123354.AUDR01000003_gene1545	9.69e-71	230.0	COG3146@1|root,COG3146@2|Bacteria,1R5A3@1224|Proteobacteria,2VNZT@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Peptidogalycan biosysnthesis/recognition	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6,FemAB_like
k59_580995_1	1121918.ARWE01000001_gene1177	1.28e-99	298.0	COG2089@1|root,COG2089@2|Bacteria,1MWG3@1224|Proteobacteria,42ME3@68525|delta/epsilon subdivisions,2WJXH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM N-acetylneuraminic acid synthase	pseI	-	2.5.1.56,2.5.1.97	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	-	R01804,R04435,R09841	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
k59_927002_1	1132855.KB913035_gene2390	4.11e-117	347.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,2VJ86@28216|Betaproteobacteria,2KKV4@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
k59_278642_2	1123514.KB905899_gene1313	9.84e-46	169.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,1RPSJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
k59_392778_1	159087.Daro_2988	9.57e-34	124.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,2VIBN@28216|Betaproteobacteria,2KVXU@206389|Rhodocyclales	206389|Rhodocyclales	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
k59_392778_2	1121035.AUCH01000019_gene2865	6.09e-90	264.0	COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,2VQ2J@28216|Betaproteobacteria,2KW72@206389|Rhodocyclales	206389|Rhodocyclales	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
k59_454946_1	1249480.B649_00020	4.64e-66	215.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1RGCV@1224|Proteobacteria,42M47@68525|delta/epsilon subdivisions,2YMRS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	(EAL) domain protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_392794_1	1122605.KB893626_gene2507	2.28e-10	62.0	COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,1IR8Z@117747|Sphingobacteriia	976|Bacteroidetes	Q	PFAM D-aminoacylase, C-terminal region	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
k59_392795_1	1121035.AUCH01000017_gene2265	1.4e-77	244.0	COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,2VH44@28216|Betaproteobacteria,2KY4V@206389|Rhodocyclales	206389|Rhodocyclales	U	alanine symporter	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
k59_1750094_2	1249480.B649_03930	2.28e-62	214.0	COG2304@1|root,COG2373@1|root,COG2931@1|root,COG2304@2|Bacteria,COG2373@2|Bacteria,COG2931@2|Bacteria,1PGYM@1224|Proteobacteria,42YEY@68525|delta/epsilon subdivisions,2YRCA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1871797_1	1537917.JU82_08350	1.11e-130	393.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,42KZ9@68525|delta/epsilon subdivisions,2YMS4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_1396050_1	709032.Sulku_1608	2.47e-99	305.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1R5RS@1224|Proteobacteria,42M3K@68525|delta/epsilon subdivisions,2YN6E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	PFAM biotin lipoyl attachment domain-containing protein	pycB	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
k59_581786_1	709032.Sulku_2274	7.45e-95	276.0	COG0080@1|root,COG0080@2|Bacteria,1RA2M@1224|Proteobacteria,42RE7@68525|delta/epsilon subdivisions,2YNWY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
k59_865870_1	1208921.ST1E_0828	7.31e-14	70.9	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,2VJF7@28216|Betaproteobacteria,1KPWB@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	I	malonyl CoA-acyl carrier protein transacylase	fabD	GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.39	ko:K00645,ko:K13935,ko:K15355	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
k59_865870_2	292415.Tbd_1549	7.51e-35	127.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,2VJ3S@28216|Betaproteobacteria,1KS53@119069|Hydrogenophilales	119069|Hydrogenophilales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_1631742_1	1249480.B649_00850	1.16e-99	300.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,42MGM@68525|delta/epsilon subdivisions,2YMUV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
k59_1285705_1	1243664.CAVL020000049_gene5062	1.91e-27	108.0	COG0778@1|root,COG0778@2|Bacteria,1UYXM@1239|Firmicutes,4HD96@91061|Bacilli,1ZGXE@1386|Bacillus	91061|Bacilli	C	nitroreductase	yfhC	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_279632_1	1249480.B649_06400	4.05e-118	340.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,42MND@68525|delta/epsilon subdivisions,2YMH3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	serine acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep
k59_455726_1	709032.Sulku_0857	4.8e-60	189.0	2FGS9@1|root,348MQ@2|Bacteria,1P3H2@1224|Proteobacteria,42SDS@68525|delta/epsilon subdivisions,2YPE7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF4149
k59_166516_1	666681.M301_2628	1.13e-36	127.0	COG0537@1|root,COG0537@2|Bacteria,1MZVD@1224|Proteobacteria,2VU7S@28216|Betaproteobacteria,2KMRM@206350|Nitrosomonadales	206350|Nitrosomonadales	FG	PFAM histidine triad (HIT) protein	-	-	-	-	-	-	-	-	-	-	-	-	HIT
k59_166516_2	666681.M301_2629	2.9e-63	194.0	COG3411@1|root,COG3411@2|Bacteria,1MZR4@1224|Proteobacteria,2VTY1@28216|Betaproteobacteria,2KMYE@206350|Nitrosomonadales	206350|Nitrosomonadales	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx
k59_1396117_1	159087.Daro_3519	4.48e-83	248.0	COG1607@1|root,COG1607@2|Bacteria,1RAEQ@1224|Proteobacteria,2VQ4Q@28216|Betaproteobacteria,2KW3J@206389|Rhodocyclales	206389|Rhodocyclales	I	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
k59_700193_1	1304883.KI912532_gene2075	5.84e-14	66.6	COG1539@1|root,COG1539@2|Bacteria	2|Bacteria	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	-	1.13.11.81,2.5.1.15,2.7.6.3,4.1.2.25,5.1.99.8	ko:K00796,ko:K00950,ko:K01633,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00840,M00841	R03066,R03067,R03503,R03504,R11037,R11073	RC00002,RC00017,RC00121,RC00721,RC00842,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB,HPPK
k59_1396119_1	1124983.PFLCHA0_c31460	6.06e-15	79.7	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMV2@1236|Gammaproteobacteria,1YPYT@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	T	chemotaxis, protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_2,sCache_2
k59_865931_1	583345.Mmol_1888	6.19e-72	218.0	COG0853@1|root,COG0853@2|Bacteria,1RI1B@1224|Proteobacteria,2VSDU@28216|Betaproteobacteria,2KMU9@206350|Nitrosomonadales	206350|Nitrosomonadales	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
k59_865931_2	583345.Mmol_1889	1.13e-48	157.0	COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,2VRRV@28216|Betaproteobacteria,2KMSE@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
k59_223172_1	709032.Sulku_2604	5.21e-104	311.0	COG3213@1|root,COG3213@2|Bacteria,1QDV8@1224|Proteobacteria,42Q6A@68525|delta/epsilon subdivisions,2YNFJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	protein involved in response to NO	-	-	-	ko:K07234	-	-	-	-	ko00000	-	-	-	NnrS
k59_887303_2	1249480.B649_01125	4.55e-09	57.4	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2YTAQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
k59_1063004_1	1249480.B649_11255	8.73e-64	213.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,42MEI@68525|delta/epsilon subdivisions,2YN3Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Asparagine synthase, glutamine-hydrolyzing	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_1709075_1	709032.Sulku_1757	2.41e-12	66.6	COG1305@1|root,COG4196@1|root,COG1305@2|Bacteria,COG4196@2|Bacteria,1MVAG@1224|Proteobacteria,42P26@68525|delta/epsilon subdivisions,2YN89@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Putative amidoligase enzyme (DUF2126)	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,DUF2126,Transglut_core
k59_1709075_2	709032.Sulku_1756	3.2e-101	317.0	COG2307@1|root,COG2308@1|root,COG2307@2|Bacteria,COG2308@2|Bacteria,1MX5P@1224|Proteobacteria,42NB9@68525|delta/epsilon subdivisions,2YNN4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E,CP_ATPgrasp_2
k59_709978_1	159087.Daro_3019	5.91e-87	259.0	COG5490@1|root,COG5490@2|Bacteria,1R4SV@1224|Proteobacteria,2VQP2@28216|Betaproteobacteria,2KW96@206389|Rhodocyclales	206389|Rhodocyclales	S	Phasin protein	-	-	-	-	-	-	-	-	-	-	-	-	Phasin_2
k59_709978_2	159087.Daro_0497	1.27e-05	45.1	COG3631@1|root,COG3631@2|Bacteria,1MZS5@1224|Proteobacteria,2VSD2@28216|Betaproteobacteria,2KWYK@206389|Rhodocyclales	206389|Rhodocyclales	S	SnoaL-like domain	-	-	5.3.3.1	ko:K01822	ko00140,ko00984,ko01100,ko01120,map00140,map00984,map01100,map01120	M00107,M00110	R01837,R02216,R02499,R02840,R03327,R04163,R04678,R04849,R09955	RC00146,RC00762	ko00000,ko00001,ko00002,ko01000	-	-	-	SnoaL_2
k59_653948_1	1385517.N800_15085	5.4e-99	301.0	COG0446@1|root,COG0446@2|Bacteria,1QUQF@1224|Proteobacteria,1RP1H@1236|Gammaproteobacteria,1X5BD@135614|Xanthomonadales	135614|Xanthomonadales	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_1534270_1	1123326.JFBL01000001_gene1390	8.21e-84	270.0	COG3437@1|root,COG4252@1|root,COG3437@2|Bacteria,COG4252@2|Bacteria,1MUB8@1224|Proteobacteria,42MFV@68525|delta/epsilon subdivisions,2YM95@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	CHASE2	-	-	-	-	-	-	-	-	-	-	-	-	CHASE2,HD
k59_477020_1	709032.Sulku_0982	5.21e-114	344.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2YMMT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_1709086_1	709032.Sulku_2251	2.26e-26	107.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,42M1T@68525|delta/epsilon subdivisions,2YMJ5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Cell division protein FtsI penicillin-binding protein	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
k59_299318_1	717773.Thicy_0241	5.11e-70	240.0	COG0247@1|root,COG0277@1|root,COG0479@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,COG0479@2|Bacteria,1MU43@1224|Proteobacteria,1RMRH@1236|Gammaproteobacteria,45ZTB@72273|Thiotrichales	72273|Thiotrichales	C	Domain of unknown function (DUF3400)	-	-	-	-	-	-	-	-	-	-	-	-	CCG,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_8
k59_1709091_1	709032.Sulku_0958	3.59e-42	149.0	COG1306@1|root,COG1306@2|Bacteria,1MWBY@1224|Proteobacteria,42NSR@68525|delta/epsilon subdivisions,2YP0V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Putative glycosyl hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4015
k59_1709091_2	1116472.MGMO_6c00170	7.89e-10	59.7	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1XDKX@135618|Methylococcales	135618|Methylococcales	JKL	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k59_829214_2	326298.Suden_1477	2.73e-89	278.0	COG1070@1|root,COG1070@2|Bacteria,1MWS5@1224|Proteobacteria,43CSA@68525|delta/epsilon subdivisions,2YNV8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	COG1070 Sugar (pentulose and hexulose)	-	-	2.7.1.189	ko:K11216	ko02024,map02024	-	R11183	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
k59_1063037_1	159087.Daro_2977	4.82e-112	328.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,2VI9W@28216|Betaproteobacteria,2KUAU@206389|Rhodocyclales	206389|Rhodocyclales	O	HflC and HflK could regulate a protease	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
k59_1827959_1	1249480.B649_05750	8.08e-62	203.0	COG1538@1|root,COG1538@2|Bacteria,1PBTH@1224|Proteobacteria,42R59@68525|delta/epsilon subdivisions,2YP2M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_887334_1	1304883.KI912532_gene141	4.31e-35	129.0	COG1868@1|root,COG1868@2|Bacteria,1MX01@1224|Proteobacteria,2VI0A@28216|Betaproteobacteria,2KV75@206389|Rhodocyclales	206389|Rhodocyclales	N	flagellar motor switch protein	fliM	-	-	ko:K02416	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliM,FliMN_C
k59_887334_2	62928.azo2724	6.58e-58	184.0	COG1886@1|root,COG1886@2|Bacteria,1RGWT@1224|Proteobacteria,2VSZ7@28216|Betaproteobacteria,2KWB5@206389|Rhodocyclales	206389|Rhodocyclales	N	Flagellar motor switch	fliN	-	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FliMN_C
k59_1122908_1	87626.PTD2_00651	2.82e-09	53.1	COG2975@1|root,COG2975@2|Bacteria,1N7C1@1224|Proteobacteria,1SC9F@1236|Gammaproteobacteria,2Q3IZ@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Iron-sulphur cluster assembly	iscX	GO:0003674,GO:0004857,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0030234,GO:0031163,GO:0043086,GO:0043167,GO:0043169,GO:0044085,GO:0044092,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050790,GO:0051186,GO:0065007,GO:0065009,GO:0071840,GO:0098772	-	-	-	-	-	-	-	-	-	-	Fe-S_assembly
k59_1122908_2	159087.Daro_1958	1.53e-43	142.0	COG0727@1|root,COG0727@2|Bacteria,1MZPF@1224|Proteobacteria,2VX2K@28216|Betaproteobacteria,2KZAI@206389|Rhodocyclales	206389|Rhodocyclales	S	Putative zinc- or iron-chelating domain	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
k59_1122908_3	159087.Daro_1959	8.91e-40	132.0	COG4628@1|root,COG4628@2|Bacteria,1N7DG@1224|Proteobacteria,2VW2Y@28216|Betaproteobacteria,2KXDU@206389|Rhodocyclales	206389|Rhodocyclales	S	Pfam:DUF2132	-	-	-	-	-	-	-	-	-	-	-	-	VF530
k59_1767829_1	317025.Tcr_1303	2.25e-82	266.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,1RNES@1236|Gammaproteobacteria,460C3@72273|Thiotrichales	72273|Thiotrichales	E	PFAM Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k59_1767829_2	376686.Fjoh_2791	1.01e-46	156.0	COG2954@1|root,COG2954@2|Bacteria,4NNGE@976|Bacteroidetes,1I1YE@117743|Flavobacteriia,2NW17@237|Flavobacterium	976|Bacteroidetes	S	Adenylate cyclase	cyaA	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CYTH
k59_241511_1	497321.C664_04042	1.15e-18	91.7	COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,2VPB3@28216|Betaproteobacteria,2KVVY@206389|Rhodocyclales	206389|Rhodocyclales	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_4,TPR_8
k59_1063071_1	709032.Sulku_1117	4.37e-129	389.0	COG2197@1|root,COG4191@1|root,COG2197@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42R06@68525|delta/epsilon subdivisions,2YP00@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9
k59_477096_1	159087.Daro_1547	3.33e-136	403.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2VH0Y@28216|Betaproteobacteria,2KU6T@206389|Rhodocyclales	206389|Rhodocyclales	I	3-hydroxyacyl-CoA dehydrogenase	-	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
k59_1297872_1	553220.CAMGR0001_2504	1.19e-38	148.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2YMJS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,NIT,Response_reg
k59_358491_1	395494.Galf_2837	8.33e-08	53.1	COG0438@1|root,COG0438@2|Bacteria,1PFQV@1224|Proteobacteria,2VXTU@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
k59_358491_2	404380.Gbem_1616	5.79e-72	228.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
k59_1063088_1	1249480.B649_05440	8.59e-119	340.0	COG0745@1|root,COG0745@2|Bacteria,1Q4AG@1224|Proteobacteria,42YR3@68525|delta/epsilon subdivisions,2YR20@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_1122950_1	1165841.SULAR_07805	3.18e-85	284.0	COG1629@1|root,COG1629@2|Bacteria,1MX4K@1224|Proteobacteria,42WVW@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
k59_1122950_2	387093.SUN_2276	8.14e-42	153.0	COG3203@1|root,COG3203@2|Bacteria,1QZ2N@1224|Proteobacteria,42QVI@68525|delta/epsilon subdivisions,2YP28@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1005741_1	1537917.JU82_01960	4.91e-107	319.0	COG3347@1|root,COG3347@2|Bacteria,1QVWU@1224|Proteobacteria,43CKY@68525|delta/epsilon subdivisions,2YNA2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	IQ	PFAM Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
k59_477112_1	1304888.ATWF01000002_gene340	1.98e-25	106.0	COG1033@1|root,COG1033@2|Bacteria,2GFIN@200930|Deferribacteres	200930|Deferribacteres	K	Sterol-sensing domain of SREBP cleavage-activation	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_477112_2	1304888.ATWF01000002_gene339	6.69e-09	57.4	COG2834@1|root,COG2834@2|Bacteria,2GG12@200930|Deferribacteres	200930|Deferribacteres	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
k59_8394_1	1537917.JU82_01535	7.34e-89	271.0	COG2710@1|root,COG2710@2|Bacteria,1MWSX@1224|Proteobacteria,42P89@68525|delta/epsilon subdivisions,2YN9D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the NifD NifK NifE NifN family	-	-	-	ko:K02592	-	-	-	-	ko00000	-	-	-	Oxidored_nitro
k59_710047_1	1165841.SULAR_06123	1.47e-155	453.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2YMRM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
k59_1709169_1	1165841.SULAR_06483	0.000476	42.7	COG2194@1|root,COG2194@2|Bacteria,1MWS7@1224|Proteobacteria,42MI1@68525|delta/epsilon subdivisions,2YMPQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Sulfatase	eptA	-	2.7.8.43	ko:K03760	ko01503,map01503	M00722	R11555,R11556,R11557	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DUF1705,Sulfatase
k59_1709169_2	1249480.B649_11070	1.61e-95	298.0	COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,42P62@68525|delta/epsilon subdivisions,2YNNE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k59_769027_1	1537917.JU82_11025	3.63e-111	328.0	COG0601@1|root,COG0601@2|Bacteria,1NS80@1224|Proteobacteria,42N5D@68525|delta/epsilon subdivisions,2YMX1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	ABC transporter permease	nikY	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
k59_1650608_1	159087.Daro_2728	4.58e-74	239.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,2KV7D@206389|Rhodocyclales	206389|Rhodocyclales	NT	Cache_2	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,dCache_2,sCache_2
k59_594056_1	90813.JQMT01000001_gene1441	2.22e-73	233.0	COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,1RQ1Q@1236|Gammaproteobacteria,45ZV5@72273|Thiotrichales	72273|Thiotrichales	S	PFAM Phosphotransferase enzyme family	-	-	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
k59_1650616_1	1249480.B649_01005	5.59e-49	171.0	2C99Z@1|root,2Z9YV@2|Bacteria,1N0B7@1224|Proteobacteria,42P3M@68525|delta/epsilon subdivisions,2YMWY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF3373)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3373
k59_1063148_1	317025.Tcr_0200	1.1e-49	171.0	COG2199@1|root,COG3706@2|Bacteria,1NC00@1224|Proteobacteria,1RR2D@1236|Gammaproteobacteria,460S3@72273|Thiotrichales	72273|Thiotrichales	T	diguanylate cyclase	-	-	2.7.7.65	ko:K13590	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF
k59_829338_1	717772.THIAE_00630	5.06e-86	256.0	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,1RMQW@1236|Gammaproteobacteria,4605S@72273|Thiotrichales	72273|Thiotrichales	EH	Glutamine amidotransferase of anthranilate synthase	-	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
k59_829338_2	1283284.AZUK01000001_gene707	1.87e-07	52.8	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1Y56A@135624|Aeromonadales	135624|Aeromonadales	T	5TMR of 5TMR-LYT	-	-	-	-	-	-	-	-	-	-	-	-	5TM-5TMR_LYT,EAL,GGDEF,PAS_4
k59_182024_1	709032.Sulku_2078	1.75e-76	241.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,42MET@68525|delta/epsilon subdivisions,2YMVE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	phosphomannomutase	glmM_1	-	5.4.2.2,5.4.2.8	ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_182024_2	709032.Sulku_2079	2.28e-61	199.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,42M8M@68525|delta/epsilon subdivisions,2YNUK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Ammonium Transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
k59_477201_1	709032.Sulku_1659	5.27e-51	175.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42QQC@68525|delta/epsilon subdivisions,2YPD6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	SMART GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
k59_1063172_1	1249480.B649_10250	6.04e-32	124.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Histidine kinase A domain protein	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3,dCache_1
k59_1063172_2	1249480.B649_10255	2.97e-33	120.0	COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,42SB8@68525|delta/epsilon subdivisions,2YPI9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA	gidB	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
k59_358561_1	365044.Pnap_1634	1.7e-29	122.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,2VJCZ@28216|Betaproteobacteria,4AAY1@80864|Comamonadaceae	28216|Betaproteobacteria	O	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	ppiD	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
k59_536725_1	709032.Sulku_1108	1.55e-08	54.7	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,42NYD@68525|delta/epsilon subdivisions,2YNI5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Permease, YjgP YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_536725_2	1249480.B649_04630	4.14e-85	256.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,42S2A@68525|delta/epsilon subdivisions,2YP5V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NOU	Peptidase A24	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
k59_1767947_1	583345.Mmol_0242	1.3e-98	304.0	COG1450@1|root,COG1450@2|Bacteria,1MVNC@1224|Proteobacteria,2VMT1@28216|Betaproteobacteria,2KKGD@206350|Nitrosomonadales	206350|Nitrosomonadales	NU	type II and III secretion system protein	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N_2
k59_1416225_1	1249480.B649_04145	7.13e-152	431.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,42MG3@68525|delta/epsilon subdivisions,2YMCB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	ABC-type transport system involved in resistance to organic solvents permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
k59_1181122_1	666681.M301_0214	1.91e-13	70.1	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1MWPE@1224|Proteobacteria,2VI4V@28216|Betaproteobacteria,2KKZV@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
k59_1181122_2	1132855.KB913035_gene388	2.57e-42	143.0	29CX4@1|root,2ZZV8@2|Bacteria,1RFY7@1224|Proteobacteria,2VR98@28216|Betaproteobacteria,2KN1E@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Domain of unknown function (DUF4390)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4390
k59_299447_1	1218076.BAYB01000006_gene1056	1.01e-41	152.0	COG3550@1|root,COG3550@2|Bacteria,1R5CM@1224|Proteobacteria,2VH9A@28216|Betaproteobacteria,1KFUP@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Pfam:HipA_N	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
k59_1416240_1	1249480.B649_03510	2.12e-106	335.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,42MGK@68525|delta/epsilon subdivisions,2YMHU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_1181137_1	1122599.AUGR01000018_gene3960	1.09e-14	80.1	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,1RPC6@1236|Gammaproteobacteria,1XIKY@135619|Oceanospirillales	135619|Oceanospirillales	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA	recB	-	3.1.11.5	ko:K03582	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
k59_594132_2	522306.CAP2UW1_1702	2.17e-89	266.0	COG1309@1|root,COG1309@2|Bacteria,1N659@1224|Proteobacteria,2VS47@28216|Betaproteobacteria	28216|Betaproteobacteria	K	PFAM regulatory protein TetR	acrR	-	-	ko:K03577	-	M00647	-	-	ko00000,ko00002,ko03000	-	-	-	TetR_C_2,TetR_N
k59_1181144_1	1249480.B649_10295	9.11e-93	277.0	COG2863@1|root,COG2863@2|Bacteria,1Q4WC@1224|Proteobacteria,42NFN@68525|delta/epsilon subdivisions,2YMWE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Plasminogen-binding protein pgbA N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PGBA_N
k59_241668_2	1122975.AQVC01000038_gene1814	9.7e-45	149.0	COG3743@1|root,COG3743@2|Bacteria,4NQGZ@976|Bacteroidetes,2FT5C@200643|Bacteroidia,230IQ@171551|Porphyromonadaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4332)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4332,HHH_5
k59_1241102_1	1249480.B649_08015	3.24e-21	90.1	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,42MV7@68525|delta/epsilon subdivisions,2YMFH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
k59_1534493_1	598659.NAMH_0020	5.65e-14	75.1	2EJXW@1|root,33DNI@2|Bacteria,1NJTD@1224|Proteobacteria,42XYW@68525|delta/epsilon subdivisions,2YSJ5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	LPP20 lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	LPP20
k59_1298001_1	1026882.MAMP_02259	3.67e-58	194.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,1RN9N@1236|Gammaproteobacteria,46052@72273|Thiotrichales	72273|Thiotrichales	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
k59_829418_1	709032.Sulku_0957	1.62e-81	254.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,42MIH@68525|delta/epsilon subdivisions,2YRA4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing EAL and modified HD-GYP domains	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
k59_1241108_1	1304883.KI912532_gene150	2.72e-81	249.0	COG1705@1|root,COG3951@1|root,COG1705@2|Bacteria,COG3951@2|Bacteria,1MX2W@1224|Proteobacteria,2VH35@28216|Betaproteobacteria,2KW3R@206389|Rhodocyclales	206389|Rhodocyclales	N	Flagellar rod assembly protein muramidase FlgJ	flgJ	-	-	ko:K02395	-	-	-	-	ko00000,ko02035	-	-	-	Glucosaminidase,Rod-binding
k59_1241108_2	266940.Krad_1622	5.23e-08	57.0	COG1256@1|root,COG1256@2|Bacteria,2GNXQ@201174|Actinobacteria	201174|Actinobacteria	N	flagellar hook-associated protein	flgK	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k59_1063252_1	1537917.JU82_03730	7.37e-129	376.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,42N4K@68525|delta/epsilon subdivisions,2YMVY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	HI0933 family	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
k59_829433_1	666681.M301_2149	9.61e-34	119.0	COG3152@1|root,COG3152@2|Bacteria,1MZJ4@1224|Proteobacteria,2VWQY@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF805)	-	-	-	-	-	-	-	-	-	-	-	-	DUF805
k59_1005926_1	709032.Sulku_1488	7.27e-199	563.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,42M1X@68525|delta/epsilon subdivisions,2YMQ9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	acetolactate synthase	ilvI	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_1592154_1	1249480.B649_00595	8.75e-123	375.0	COG0715@1|root,COG0834@1|root,COG4191@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PNA@68525|delta/epsilon subdivisions,2YTBI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EPT	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,NMT1,SBP_bac_3
k59_1006824_1	159087.Daro_4104	1.1e-84	253.0	COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,2VR3B@28216|Betaproteobacteria,2KWCK@206389|Rhodocyclales	206389|Rhodocyclales	J	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA	gidB	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
k59_1006824_2	159087.Daro_4105	1.51e-59	189.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,2VHNK@28216|Betaproteobacteria,2KV5R@206389|Rhodocyclales	206389|Rhodocyclales	D	involved in chromosome partitioning	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
k59_65620_1	935863.AWZR01000003_gene2637	3.26e-59	198.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,1RN13@1236|Gammaproteobacteria,1X44W@135614|Xanthomonadales	135614|Xanthomonadales	F	Catalyzes the hydrolytic cleavage of a carbon-halogen bond in N-ethylammeline	-	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k59_655058_1	159087.Daro_1891	1.67e-39	134.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2VQ9M@28216|Betaproteobacteria,2KWI4@206389|Rhodocyclales	206389|Rhodocyclales	C	[2Fe-2S] binding domain	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
k59_1242075_1	159087.Daro_0846	1.68e-124	360.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,2VIQ4@28216|Betaproteobacteria,2KUG2@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
k59_1651567_1	305700.B447_11872	1.42e-69	233.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KUCK@206389|Rhodocyclales	206389|Rhodocyclales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CZB,EAL,GAF,GGDEF,PAS,PAS_4,PAS_9,Response_reg
k59_1357418_1	1249480.B649_11360	4.28e-139	422.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YMHP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF,PAS_4
k59_65640_1	394503.Ccel_3423	1.06e-77	253.0	COG3973@1|root,COG3973@2|Bacteria,1TP39@1239|Firmicutes,249IG@186801|Clostridia,36E3M@31979|Clostridiaceae	186801|Clostridia	L	DNA helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_19,UvrD-helicase,UvrD_C,UvrD_C_2
k59_125895_1	1249480.B649_05830	6.85e-74	225.0	2AJ4F@1|root,319NZ@2|Bacteria,1Q3DH@1224|Proteobacteria,42X57@68525|delta/epsilon subdivisions,2YQQ1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_610412_3	1537917.JU82_04435	7.75e-61	192.0	COG0212@1|root,COG0212@2|Bacteria,1RDZJ@1224|Proteobacteria,42SXM@68525|delta/epsilon subdivisions,2YPJD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	-	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
k59_1140454_1	399795.CtesDRAFT_PD0374	1.01e-111	329.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,2VHGF@28216|Betaproteobacteria,4AE59@80864|Comamonadaceae	28216|Betaproteobacteria	M	NAD(P)H-binding	capD	-	4.2.1.115,5.1.3.2	ko:K15894,ko:K17716	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00362	R00291,R09697	RC00289,RC02609	ko00000,ko00001,ko00002,ko01000	-	-	-	Polysacc_syn_2C,Polysacc_synt_2
k59_1723975_1	697282.Mettu_2965	8.02e-55	194.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,MASE1,PAS,PAS_3,PAS_4,PAS_9
k59_1025609_1	929558.SMGD1_0378	8.68e-104	326.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2YMB9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	chemotaxis protein	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
k59_1372016_1	1537917.JU82_08040	2.08e-144	429.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2YMW4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_784486_1	1229485.AMYV01000156_gene2688	5.68e-29	110.0	COG3787@1|root,COG3787@2|Bacteria,1RH76@1224|Proteobacteria,1S6F1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the UPF0306 family	yhbP	-	-	ko:K09979	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
k59_672353_2	502025.Hoch_6116	1.11e-23	101.0	COG0282@1|root,COG4869@1|root,COG0282@2|Bacteria,COG4869@2|Bacteria,1MW61@1224|Proteobacteria,42MJA@68525|delta/epsilon subdivisions,2WJBJ@28221|Deltaproteobacteria,2YUMX@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase,PTAC
k59_371906_1	159087.Daro_3094	1.06e-62	192.0	COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,2VSCU@28216|Betaproteobacteria,2KWPQ@206389|Rhodocyclales	206389|Rhodocyclales	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
k59_371906_2	1165096.ARWF01000001_gene1109	3e-28	112.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,2VH1K@28216|Betaproteobacteria,2KKYH@206350|Nitrosomonadales	206350|Nitrosomonadales	O	TIGRFAM ATP-dependent Clp protease ATP-binding subunit clpA	-	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_256761_1	1249480.B649_10230	1.25e-212	595.0	COG3303@1|root,COG3303@2|Bacteria,1QUJG@1224|Proteobacteria,42RGW@68525|delta/epsilon subdivisions,2YMPH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
k59_256761_2	1249480.B649_10225	7.32e-36	122.0	2A4UE@1|root,30TFZ@2|Bacteria,1PDA5@1224|Proteobacteria,42WVN@68525|delta/epsilon subdivisions,2YQRH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_555366_1	159087.Daro_3935	1.89e-39	138.0	COG0524@1|root,COG0524@2|Bacteria,1PDQE@1224|Proteobacteria,2VHMF@28216|Betaproteobacteria,2KUNE@206389|Rhodocyclales	206389|Rhodocyclales	G	COG0524 Sugar kinases, ribokinase family	pfkB	-	2.7.1.20	ko:K00856	ko00230,ko01100,map00230,map01100	-	R00185	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
k59_371918_1	159087.Daro_0858	2.41e-37	134.0	COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,2VJA4@28216|Betaproteobacteria,2KUQ4@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
k59_371918_2	159087.Daro_0859	4.87e-41	136.0	COG2841@1|root,COG2841@2|Bacteria,1PJWS@1224|Proteobacteria,2W88I@28216|Betaproteobacteria,2KZMI@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF465)	-	-	-	ko:K09794	-	-	-	-	ko00000	-	-	-	DUF465
k59_1782577_1	1165841.SULAR_03218	1.91e-79	246.0	COG1792@1|root,COG1792@2|Bacteria,1QB26@1224|Proteobacteria,42MF4@68525|delta/epsilon subdivisions,2YNT9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Rod shape-determining protein MreC	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
k59_1195326_2	1249480.B649_00205	1.02e-148	428.0	COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,42UBK@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	SMART Metal-dependent phosphohydrolase, HD region	-	-	-	-	-	-	-	-	-	-	-	-	DUF3391,HD,HD_5
k59_1195326_3	1537917.JU82_03095	1.43e-57	184.0	2AIM2@1|root,319HK@2|Bacteria,1Q2ST@1224|Proteobacteria,42W74@68525|delta/epsilon subdivisions,2YQAM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_142435_1	709032.Sulku_1585	3.73e-32	115.0	COG2050@1|root,COG2050@2|Bacteria,1N1PP@1224|Proteobacteria,42TRH@68525|delta/epsilon subdivisions,2YPTG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	thioesterase	-	-	-	ko:K02614	ko00360,map00360	-	R09840	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	4HBT
k59_142435_2	709032.Sulku_1584	4.63e-82	246.0	COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,42QWD@68525|delta/epsilon subdivisions,2YNVD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COG0491 Zn-dependent hydrolases, including glyoxylases	ycbL	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_20815_1	709032.Sulku_1891	1.75e-99	294.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,42QV4@68525|delta/epsilon subdivisions,2YMTK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
k59_1552597_1	522306.CAP2UW1_0976	2.96e-24	97.1	2FH2G@1|root,348X9@2|Bacteria,1P05V@1224|Proteobacteria,2W3Y8@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1724029_2	709032.Sulku_1300	6.52e-99	288.0	COG0716@1|root,COG0716@2|Bacteria,1QRBW@1224|Proteobacteria,43ACU@68525|delta/epsilon subdivisions,2YT0R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Low-potential electron donor to a number of redox enzymes	-	-	-	ko:K03839	-	-	-	-	ko00000	-	-	-	Flavodoxin_1
k59_784545_1	709032.Sulku_0301	4.33e-44	148.0	2AIHQ@1|root,318ZM@2|Bacteria,1Q19H@1224|Proteobacteria,42T48@68525|delta/epsilon subdivisions,2YPGP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_784545_2	1249480.B649_01315	4.68e-78	237.0	COG3166@1|root,COG3166@2|Bacteria,1Q1VC@1224|Proteobacteria,42UGS@68525|delta/epsilon subdivisions,2YPY1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	PFAM Fimbrial assembly family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_784545_3	1537917.JU82_09955	4.03e-25	101.0	2BQX9@1|root,32JUG@2|Bacteria,1Q2H0@1224|Proteobacteria,42VPF@68525|delta/epsilon subdivisions,2YQMK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1195359_1	1216967.L100_07774	1.07e-23	95.5	COG2010@1|root,COG2010@2|Bacteria,4NQN1@976|Bacteroidetes,1I3G4@117743|Flavobacteriia,34RED@308865|Elizabethkingia	976|Bacteroidetes	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
k59_1846206_1	1123514.KB905902_gene226	8.32e-94	283.0	COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,1RMNR@1236|Gammaproteobacteria,4609K@72273|Thiotrichales	72273|Thiotrichales	E	Aminotransferase class-V	-	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
k59_1025728_1	477228.YO5_07022	1.25e-116	347.0	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,1RMFQ@1236|Gammaproteobacteria,1Z2FC@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0007059,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0022607,GO:0022611,GO:0022613,GO:0022618,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0043021,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0065003,GO:0065007,GO:0070925,GO:0071826,GO:0071840,GO:0090069,GO:0090071,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
k59_555487_1	1249480.B649_05890	6.27e-37	130.0	COG1451@1|root,COG1451@2|Bacteria,1MXZU@1224|Proteobacteria,42V1Y@68525|delta/epsilon subdivisions,2YQDY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	hmm pf01863	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
k59_720977_1	1537917.JU82_03520	2.45e-99	295.0	COG1686@1|root,COG1686@2|Bacteria,1MWZA@1224|Proteobacteria,43AWC@68525|delta/epsilon subdivisions,2YT3V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
k59_1310015_1	768671.ThimaDRAFT_4023	2.07e-105	330.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,1RPF7@1236|Gammaproteobacteria,1WWWW@135613|Chromatiales	135613|Chromatiales	CO	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
k59_610596_1	709032.Sulku_0607	1.93e-151	429.0	COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,42PR1@68525|delta/epsilon subdivisions,2YMT0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	forms the ion channels that couple flagellar rotation to proton sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine	motA	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
k59_77254_1	709032.Sulku_1444	3e-39	142.0	COG0579@1|root,COG0579@2|Bacteria,1MUCC@1224|Proteobacteria,42M2Q@68525|delta/epsilon subdivisions,2YMYG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Malate quinone- oxidoreductase	mqo	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.1.5.4	ko:K00116	ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00009,M00011	R00360,R00361,R01257	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0086	Mqo
k59_77254_2	709032.Sulku_1505	3.55e-32	127.0	COG2199@1|root,COG3706@2|Bacteria,1R1K2@1224|Proteobacteria,42YWW@68525|delta/epsilon subdivisions,2YR1I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Double sensory domain of two-component sensor kinase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_3
k59_1846304_1	1537917.JU82_07040	4.04e-59	187.0	COG3787@1|root,COG3787@2|Bacteria,1RH76@1224|Proteobacteria,42TS4@68525|delta/epsilon subdivisions,2YPWQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	cofactor binding	Cj1449c	-	-	ko:K09979	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
k59_1846304_2	709032.Sulku_1902	1.05e-31	110.0	2EH2E@1|root,33AUC@2|Bacteria,1NI43@1224|Proteobacteria,42WYJ@68525|delta/epsilon subdivisions,2YQNV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1025838_2	1242969.ATCC51562_325	2.3e-21	94.4	COG3672@1|root,COG3672@2|Bacteria,1RDQS@1224|Proteobacteria,42QWJ@68525|delta/epsilon subdivisions,2YNVX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Bacterial transglutaminase-like cysteine proteinase BTLCP	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C93
k59_1666101_1	1283284.AZUK01000001_gene1556	5.94e-10	53.9	2DR8E@1|root,33ANS@2|Bacteria,1NI69@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1259665_1	709032.Sulku_1225	4.3e-100	303.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42MH9@68525|delta/epsilon subdivisions,2YMWG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	COG1459 Type II secretory pathway, component PulF	-	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
k59_1259665_2	709032.Sulku_1224	2.95e-31	120.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2YMIX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE
k59_494279_2	1123514.KB905901_gene146	9.01e-12	65.1	COG2945@1|root,COG2945@2|Bacteria,1MUDY@1224|Proteobacteria,1S92R@1236|Gammaproteobacteria,463J9@72273|Thiotrichales	72273|Thiotrichales	S	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Peptidase_S15
k59_1195454_1	1537917.JU82_08610	7.41e-101	298.0	COG3786@1|root,COG3786@2|Bacteria,1RH22@1224|Proteobacteria,42U32@68525|delta/epsilon subdivisions,2YPTI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COGs COG3786 conserved	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
k59_555586_1	1265502.KB905947_gene1106	3.03e-54	175.0	COG0789@1|root,COG0789@2|Bacteria,1MZ3P@1224|Proteobacteria,2VSF9@28216|Betaproteobacteria,4AEFI@80864|Comamonadaceae	28216|Betaproteobacteria	K	transcriptional regulator, MerR family	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR-DNA-bind,MerR_1
k59_1724161_1	1304883.KI912532_gene2891	1.23e-115	342.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,2VH5S@28216|Betaproteobacteria,2KVN3@206389|Rhodocyclales	206389|Rhodocyclales	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
k59_312274_1	1249480.B649_11380	7.32e-51	167.0	COG0791@1|root,COG0791@2|Bacteria,1RBV6@1224|Proteobacteria,42RZU@68525|delta/epsilon subdivisions,2YPA6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_4
k59_1372229_1	1249480.B649_11300	3.03e-76	239.0	2AIAA@1|root,318R4@2|Bacteria,1Q0T4@1224|Proteobacteria,42SFV@68525|delta/epsilon subdivisions,2YPR6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	1.13.11.63	ko:K21817	-	-	-	-	ko00000,ko01000	-	-	-	-
k59_1259715_1	709032.Sulku_1959	1.11e-115	349.0	COG3437@1|root,COG3437@2|Bacteria,1QYD6@1224|Proteobacteria,43CBH@68525|delta/epsilon subdivisions,2YTB6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	cheY-homologous receiver domain	-	-	3.1.1.61,3.5.1.44	ko:K03412,ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	Response_reg
k59_432104_1	426114.THI_3202	1.02e-11	67.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,2VHBB@28216|Betaproteobacteria,1KKAT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN2	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
k59_432104_2	1123517.JOMR01000001_gene201	2.03e-33	121.0	COG1516@1|root,COG1516@2|Bacteria	2|Bacteria	N	flagellar protein fliS	fliS	-	-	ko:K02422	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliS
k59_1724180_1	709032.Sulku_0957	3.6e-77	244.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,42MIH@68525|delta/epsilon subdivisions,2YRA4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing EAL and modified HD-GYP domains	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
k59_256974_1	1123401.JHYQ01000019_gene1505	3.96e-70	223.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,1RMKY@1236|Gammaproteobacteria,4609B@72273|Thiotrichales	72273|Thiotrichales	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10	ko:K00795	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364	R01658,R02003	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
k59_555621_1	709032.Sulku_0019	1.12e-45	163.0	COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,42RCJ@68525|delta/epsilon subdivisions,2YNX9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG4775 Outer membrane protein protective antigen OMA87	-	-	-	ko:K07278	-	-	-	-	ko00000,ko02000	1.B.33.2.4	-	-	Bac_surface_Ag,POTRA
k59_1195511_1	666681.M301_1502	1.57e-88	266.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,2VJ7N@28216|Betaproteobacteria,2KNI9@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
k59_197203_1	159087.Daro_0955	1.05e-143	426.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,2VJYV@28216|Betaproteobacteria,2KVHX@206389|Rhodocyclales	206389|Rhodocyclales	C	COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G)	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
k59_1490041_1	1304888.ATWF01000002_gene340	2.52e-45	167.0	COG1033@1|root,COG1033@2|Bacteria,2GFIN@200930|Deferribacteres	200930|Deferribacteres	K	Sterol-sensing domain of SREBP cleavage-activation	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_1490041_2	509190.Cseg_2857	5.72e-15	70.9	COG0640@1|root,COG0640@2|Bacteria,1QVGE@1224|Proteobacteria,2TWFD@28211|Alphaproteobacteria,2KK7D@204458|Caulobacterales	204458|Caulobacterales	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_34
k59_77353_1	1537917.JU82_04755	4.44e-74	228.0	COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,42SI3@68525|delta/epsilon subdivisions,2YRUU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Membrane	-	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
k59_1606649_1	709032.Sulku_2414	7.17e-90	282.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,42MMR@68525|delta/epsilon subdivisions,2YMF0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	GM	Polysaccharide biosynthesis protein	pglF	-	4.2.1.135	ko:K15912	ko00520,map00520	-	-	-	ko00000,ko00001,ko01000	-	-	-	Polysacc_synt_2
k59_494385_1	1537917.JU82_10505	1e-67	213.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,42MW0@68525|delta/epsilon subdivisions,2YM9U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
k59_494385_2	1249480.B649_07215	3.05e-33	121.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,42NJE@68525|delta/epsilon subdivisions,2YM8V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
k59_555678_1	1249480.B649_03070	3.1e-34	119.0	COG0776@1|root,COG0776@2|Bacteria,1QQYR@1224|Proteobacteria,42V36@68525|delta/epsilon subdivisions,2YQA9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the bacterial histone-like protein family	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k59_144972_2	1537917.JU82_11070	3.49e-41	139.0	COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,42QXP@68525|delta/epsilon subdivisions,2YPJE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
k59_1374361_1	1249480.B649_11775	2.15e-27	102.0	2BTTK@1|root,32P16@2|Bacteria,1Q41F@1224|Proteobacteria,42Y3I@68525|delta/epsilon subdivisions,2YQQG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1374361_2	1537917.JU82_05060	8.83e-173	503.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2YN94@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
k59_434006_1	1249480.B649_03995	2.56e-103	314.0	COG4753@1|root,COG4753@2|Bacteria,1Q8YM@1224|Proteobacteria,42YGW@68525|delta/epsilon subdivisions,2YR37@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_434006_2	1249480.B649_04000	4.94e-09	55.8	COG0426@1|root,COG0426@2|Bacteria,1N2Y0@1224|Proteobacteria,42WJ3@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_847286_1	497321.C664_17407	1.57e-74	231.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,2VHUJ@28216|Betaproteobacteria,2KWM7@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
k59_1555237_1	1122236.KB905142_gene387	2.05e-69	217.0	COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,2VJEC@28216|Betaproteobacteria,2KN5C@206350|Nitrosomonadales	206350|Nitrosomonadales	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
k59_1374368_1	640081.Dsui_1870	4.92e-28	117.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2VI5V@28216|Betaproteobacteria,2KVEZ@206389|Rhodocyclales	206389|Rhodocyclales	M	Outer membrane efflux protein	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
k59_1262181_1	1249480.B649_10060	1.56e-19	87.8	COG1287@1|root,COG1287@2|Bacteria,1R481@1224|Proteobacteria,42MNZ@68525|delta/epsilon subdivisions,2YMU3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Oligosaccharyl transferase, STT3 subunit	pglB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0034645,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046872,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.4.99.18,2.4.99.19	ko:K07151,ko:K17251	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	STT3
k59_1262181_2	639283.Snov_3219	5.92e-06	53.1	COG0110@1|root,COG0110@2|Bacteria,1MZ7U@1224|Proteobacteria,2UBQS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	GM	sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family	-	-	-	ko:K13006	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2
k59_144996_1	1165841.SULAR_06138	2.33e-25	97.1	COG1959@1|root,COG1959@2|Bacteria,1MZ1C@1224|Proteobacteria,42SJM@68525|delta/epsilon subdivisions,2YPJG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
k59_144996_2	387093.SUN_1874	3.16e-49	157.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,42TPZ@68525|delta/epsilon subdivisions,2YPU9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
k59_313785_1	709032.Sulku_0308	1.16e-106	315.0	COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria,42P5V@68525|delta/epsilon subdivisions,2YNBJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	msrP	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
k59_722683_1	709032.Sulku_1739	1.22e-72	241.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2YRKW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0474 Cation transport ATPase	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
k59_558152_1	1249480.B649_05965	8.76e-136	404.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,42N50@68525|delta/epsilon subdivisions,2YN1V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
k59_787317_1	709032.Sulku_0308	2.83e-111	325.0	COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria,42P5V@68525|delta/epsilon subdivisions,2YNBJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	msrP	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
k59_787317_2	709032.Sulku_0309	1.64e-29	110.0	COG2717@1|root,COG2717@2|Bacteria,1RDUP@1224|Proteobacteria,42VZ2@68525|delta/epsilon subdivisions,2YQGP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	PFAM Ferric reductase domain protein transmembrane component domain	-	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
k59_965525_1	1537917.JU82_05340	7.73e-48	157.0	COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,42NIV@68525|delta/epsilon subdivisions,2YN3P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Imidazoleglycerol-phosphate dehydratase	hisB	-	3.1.3.15,4.2.1.19	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013,R03457	RC00017,RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD,PNK3P
k59_965525_2	1537917.JU82_05335	6.23e-65	203.0	COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,42PQF@68525|delta/epsilon subdivisions,2YMTU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
k59_1491834_1	1537917.JU82_02925	2.11e-75	236.0	2AIMJ@1|root,3193W@2|Bacteria,1Q1QU@1224|Proteobacteria,42U73@68525|delta/epsilon subdivisions,2YSXF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_787337_1	709032.Sulku_0794	8.94e-58	199.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42UBD@68525|delta/epsilon subdivisions,2YRGP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	7TM diverse intracellular signalling	-	-	-	ko:K20971	ko02025,map02025	-	-	-	ko00000,ko00001,ko01001,ko02022	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c
k59_1555336_1	90814.KL370892_gene1951	4.83e-102	322.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria,45ZWK@72273|Thiotrichales	72273|Thiotrichales	M	TIGRFAM penicillin-binding protein, 1A	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
k59_1028754_1	1304883.KI912532_gene2242	3.02e-98	298.0	COG0642@1|root,COG3850@1|root,COG2205@2|Bacteria,COG3850@2|Bacteria,1N58A@1224|Proteobacteria,2VHVP@28216|Betaproteobacteria,2KUT7@206389|Rhodocyclales	206389|Rhodocyclales	T	Histidine kinase	yfhK	-	2.7.13.3	ko:K07711	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
k59_1082122_1	1144888.CM001467_gene328	3.29e-46	166.0	COG2227@1|root,COG4797@1|root,COG2227@2|Bacteria,COG4797@2|Bacteria,1QU8H@1224|Proteobacteria,2TWMI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	MethyTransf_Reg,Methyltransf_25,Methyltransf_31
k59_919581_1	713586.KB900536_gene2399	4.47e-127	370.0	COG4447@1|root,COG4447@2|Bacteria,1ND1J@1224|Proteobacteria,1RQ15@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	BNR_6
k59_630432_1	1485544.JQKP01000007_gene2032	2.66e-52	187.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_8,PAS_9
k59_216464_1	326298.Suden_1477	1.88e-80	255.0	COG1070@1|root,COG1070@2|Bacteria,1MWS5@1224|Proteobacteria,43CSA@68525|delta/epsilon subdivisions,2YNV8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	COG1070 Sugar (pentulose and hexulose)	-	-	2.7.1.189	ko:K11216	ko02024,map02024	-	R11183	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
k59_1624131_1	159087.Daro_2858	1.45e-90	277.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,2VIEM@28216|Betaproteobacteria,2KVIM@206389|Rhodocyclales	206389|Rhodocyclales	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	odhB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
k59_919595_1	1249480.B649_09310	2.74e-84	262.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,42MIH@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	PFAM EAL domain protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
k59_859078_1	583345.Mmol_1215	1.97e-107	312.0	296ZZ@1|root,2ZU8H@2|Bacteria,1RED2@1224|Proteobacteria,2VJPT@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1390129_1	159087.Daro_0131	9.26e-74	226.0	2F8Y9@1|root,341A3@2|Bacteria,1NZBI@1224|Proteobacteria,2W3I6@28216|Betaproteobacteria,2KYYW@206389|Rhodocyclales	206389|Rhodocyclales	S	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
k59_1047011_1	1278309.KB907101_gene525	1.89e-09	61.6	COG0697@1|root,COG0697@2|Bacteria,1N024@1224|Proteobacteria,1S1KP@1236|Gammaproteobacteria,1XJFJ@135619|Oceanospirillales	135619|Oceanospirillales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_1624160_1	1453501.JELR01000001_gene2219	9.33e-43	148.0	COG0424@1|root,COG0424@2|Bacteria,1RDA9@1224|Proteobacteria,1S3TQ@1236|Gammaproteobacteria,467IH@72275|Alteromonadaceae	1236|Gammaproteobacteria	D	COG0424 Nucleotide-binding protein implicated in inhibition of septum formation	yceF	GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0047429	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
k59_1742461_1	1537917.JU82_06590	2.49e-53	176.0	COG0330@1|root,COG0330@2|Bacteria,1N5JY@1224|Proteobacteria,42MNX@68525|delta/epsilon subdivisions,2YME9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	COG0330 Membrane protease subunits stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_919639_1	563040.Saut_2116	8.93e-45	150.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,42RFN@68525|delta/epsilon subdivisions,2YP6C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
k59_919639_2	1537917.JU82_05115	1.57e-69	224.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,42NBJ@68525|delta/epsilon subdivisions,2YMTY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Mg chelatase-related protein	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
k59_326197_1	1121459.AQXE01000001_gene2757	2.2e-66	221.0	COG1328@1|root,COG1328@2|Bacteria,1MWMS@1224|Proteobacteria,42M8V@68525|delta/epsilon subdivisions,2WJ7S@28221|Deltaproteobacteria,2M8SA@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	TIGRFAM anaerobic ribonucleoside-triphosphate reductase	-	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	NRDD
k59_735232_1	1249480.B649_01370	2.58e-33	125.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,42PFG@68525|delta/epsilon subdivisions,2YN2E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1252 NADH dehydrogenase FAD-containing subunit	ndh	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_1390179_1	1537917.JU82_03475	5.49e-56	176.0	COG3323@1|root,COG3323@2|Bacteria,1MZF5@1224|Proteobacteria,42W00@68525|delta/epsilon subdivisions,2YS8D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_326208_1	709032.Sulku_1023	1.95e-58	182.0	COG0526@1|root,COG0526@2|Bacteria,1R1JZ@1224|Proteobacteria,43EIF@68525|delta/epsilon subdivisions,2YTHD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CO	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
k59_326208_2	1537917.JU82_10560	1.31e-18	85.1	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,42MVQ@68525|delta/epsilon subdivisions,2YMEZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CO	Thiol disulfide interchange protein	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin,Thioredoxin_2,Thioredoxin_7
k59_216545_1	159087.Daro_2868	9.32e-116	338.0	COG2301@1|root,COG2301@2|Bacteria,1Q91U@1224|Proteobacteria,2VJJY@28216|Betaproteobacteria,2KUFC@206389|Rhodocyclales	206389|Rhodocyclales	G	Belongs to the HpcH HpaI aldolase family	citE	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
k59_1624224_1	1249480.B649_11160	4.6e-77	236.0	COG0124@1|root,COG0124@2|Bacteria,1QUJQ@1224|Proteobacteria,42NX2@68525|delta/epsilon subdivisions,2YN2F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	PFAM tRNA synthetase class II (G H P and S)	hisZ	-	-	-	-	-	-	-	-	-	-	-	tRNA-synt_His
k59_1327850_1	1537917.JU82_00735	1.88e-95	285.0	28M05@1|root,32SJ0@2|Bacteria,1N115@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_630506_1	159087.Daro_0763	8.13e-77	235.0	COG1338@1|root,COG1338@2|Bacteria,1MVBU@1224|Proteobacteria,2VIU6@28216|Betaproteobacteria,2KV4G@206389|Rhodocyclales	206389|Rhodocyclales	N	Plays a role in the flagellum-specific transport system	fliP	-	-	ko:K02419	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliP
k59_630506_2	1304883.KI912532_gene145	5.89e-45	146.0	COG1987@1|root,COG1987@2|Bacteria,1N73W@1224|Proteobacteria,2VU8S@28216|Betaproteobacteria,2KX39@206389|Rhodocyclales	206389|Rhodocyclales	N	Role in flagellar biosynthesis	fliQ	-	-	ko:K02420	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_3
k59_983899_1	1454004.AW11_03013	4.02e-24	98.2	COG0348@1|root,COG0348@2|Bacteria,1MWR5@1224|Proteobacteria,2VJGG@28216|Betaproteobacteria	28216|Betaproteobacteria	C	4Fe-4S binding domain	-	-	-	ko:K02574	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_5
k59_983899_2	1089552.KI911559_gene3033	1.2e-52	176.0	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,2TQQC@28211|Alphaproteobacteria,2JQ2D@204441|Rhodospirillales	204441|Rhodospirillales	E	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
k59_1455005_1	159087.Daro_0030	1.79e-49	173.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,2VIDI@28216|Betaproteobacteria,2KV2P@206389|Rhodocyclales	206389|Rhodocyclales	T	Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k59_1455005_2	159087.Daro_0031	1.33e-42	149.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VKD8@28216|Betaproteobacteria,2KV57@206389|Rhodocyclales	206389|Rhodocyclales	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activ_2
k59_1097011_1	589865.DaAHT2_0789	8.94e-76	236.0	COG0426@1|root,COG0426@2|Bacteria,1N2Y0@1224|Proteobacteria,42WJ3@68525|delta/epsilon subdivisions,2X5E1@28221|Deltaproteobacteria,2MKUJ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_1572806_1	754436.JCM19237_2946	1.85e-09	57.8	COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,1RMMT@1236|Gammaproteobacteria,1XTVH@135623|Vibrionales	135623|Vibrionales	M	Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate	mpl	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_1572806_2	580332.Slit_0508	6.14e-43	156.0	COG0557@1|root,COG0557@2|Bacteria,1NGSQ@1224|Proteobacteria,2VHMM@28216|Betaproteobacteria,44VP2@713636|Nitrosomonadales	28216|Betaproteobacteria	K	RNB	rnb	-	3.1.13.1	ko:K01147	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNB
k59_1097026_1	563040.Saut_0839	1.4e-101	310.0	COG2010@1|root,COG3391@1|root,COG2010@2|Bacteria,COG3391@2|Bacteria,1N3PN@1224|Proteobacteria,42Q19@68525|delta/epsilon subdivisions,2YNSV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	nitrite reductase	-	-	1.7.2.1,1.7.99.1	ko:K15864	ko00910,ko01120,map00910,map01120	M00529	R00143,R00783,R00785	RC00086,RC02797	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_D1,Cytochrome_CBB3
k59_35417_1	159087.Daro_0545	1.14e-60	188.0	2E4DA@1|root,33604@2|Bacteria,1NCA3@1224|Proteobacteria,2VWKE@28216|Betaproteobacteria,2KZUR@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_35417_2	159087.Daro_0546	3.26e-22	94.7	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2VH4I@28216|Betaproteobacteria,2KV7T@206389|Rhodocyclales	206389|Rhodocyclales	L	DNA helicase	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_630574_2	1537917.JU82_11505	1.33e-139	398.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,42MV7@68525|delta/epsilon subdivisions,2YMFH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
k59_1213145_1	338969.Rfer_1983	3.63e-133	416.0	COG2203@1|root,COG5000@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5000@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,4AD7J@80864|Comamonadaceae	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	CZB,EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,dCache_1
k59_919773_1	159087.Daro_3618	2.31e-85	282.0	COG0457@1|root,COG1075@1|root,COG4995@1|root,COG0457@2|Bacteria,COG1075@2|Bacteria,COG4995@2|Bacteria,1MUIQ@1224|Proteobacteria,2VKH5@28216|Betaproteobacteria,2KVCP@206389|Rhodocyclales	206389|Rhodocyclales	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,LCAT
k59_449353_1	742159.HMPREF0004_5621	4.1e-106	319.0	COG1146@1|root,COG1146@2|Bacteria,1MU2I@1224|Proteobacteria,2VJHI@28216|Betaproteobacteria,3T21S@506|Alcaligenaceae	28216|Betaproteobacteria	C	utilization protein B	citB	-	-	ko:K13795	-	-	-	-	ko00000	-	-	-	-
k59_449353_2	748247.AZKH_1926	8.36e-101	305.0	COG1053@1|root,COG1053@2|Bacteria,1MX5A@1224|Proteobacteria,2VN6P@28216|Betaproteobacteria,2KZIA@206389|Rhodocyclales	206389|Rhodocyclales	C	FAD dependent oxidoreductase	-	-	-	ko:K13796	-	-	-	-	ko00000	-	-	-	FAD_binding_2
k59_1798747_1	709032.Sulku_2618	6.59e-62	196.0	COG0664@1|root,COG0664@2|Bacteria,1RIIE@1224|Proteobacteria,42T56@68525|delta/epsilon subdivisions,2YPFT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	- catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
k59_1798747_2	709032.Sulku_2619	5.9e-07	50.4	COG3850@1|root,COG3850@2|Bacteria,1QZ2D@1224|Proteobacteria,42RD6@68525|delta/epsilon subdivisions,2YNZ2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Type IV pili methyl-accepting chemotaxis transducer N-term	-	-	-	-	-	-	-	-	-	-	-	-	PilJ
k59_919792_1	640081.Dsui_1076	1.83e-111	342.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VH8J@28216|Betaproteobacteria,2KVKK@206389|Rhodocyclales	206389|Rhodocyclales	P	P-type ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
k59_216722_2	387093.SUN_1969	1.72e-76	230.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,42THF@68525|delta/epsilon subdivisions,2YPXJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
k59_216722_3	1165841.SULAR_06753	1.91e-99	298.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,42NBS@68525|delta/epsilon subdivisions,2YMPP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	riboflavin biosynthesis protein	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
k59_735371_1	1123517.JOMR01000001_gene124	1.26e-44	157.0	COG2391@1|root,COG2391@2|Bacteria,1MXSE@1224|Proteobacteria,1RSMW@1236|Gammaproteobacteria,4628N@72273|Thiotrichales	72273|Thiotrichales	S	Sulphur transport	-	-	-	-	-	-	-	-	-	-	-	-	Sulf_transp
k59_693394_1	1123514.KB905902_gene230	9.64e-140	410.0	COG2759@1|root,COG2759@2|Bacteria,1MUR8@1224|Proteobacteria,1RME6@1236|Gammaproteobacteria,46012@72273|Thiotrichales	72273|Thiotrichales	F	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
k59_859331_1	946483.Cenrod_1746	4.66e-57	203.0	COG0642@1|root,COG0745@1|root,COG2198@1|root,COG2199@1|root,COG0745@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	bvgS2	-	-	ko:K14978	ko02020,map02020	M00663	-	-	ko00000,ko00001,ko00002,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_7,Response_reg
k59_1742771_1	1304883.KI912532_gene1716	1.01e-115	340.0	COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,2VH4W@28216|Betaproteobacteria,2KU9M@206389|Rhodocyclales	206389|Rhodocyclales	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroG	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
k59_1506451_1	1537917.JU82_10520	6.21e-182	508.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,42N8G@68525|delta/epsilon subdivisions,2YMHA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
k59_1455232_1	709032.Sulku_1984	9.57e-81	240.0	COG2198@1|root,COG2198@2|Bacteria,1Q0HI@1224|Proteobacteria,42S4B@68525|delta/epsilon subdivisions,2YP8X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	Hpt
k59_160449_1	10704.B4UTW9_BP163	7.39e-15	78.2	4QEHM@10239|Viruses,4QZJ0@35237|dsDNA viruses  no RNA stage,4QR9D@28883|Caudovirales,4QMUT@10699|Siphoviridae	10699|Siphoviridae	S	DNA polymerase III beta subunit, central domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_160449_2	1245471.PCA10_00030	2.95e-14	74.3	COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,1RN5P@1236|Gammaproteobacteria,1YETD@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
k59_1865978_1	1179778.PMM47T1_09666	2.91e-15	83.6	COG0318@1|root,COG0764@1|root,COG0318@2|Bacteria,COG0764@2|Bacteria,1MXPB@1224|Proteobacteria,1RRD5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,FabA
k59_160453_2	1172190.M947_05175	8.21e-51	176.0	COG1001@1|root,COG1001@2|Bacteria,1MVFP@1224|Proteobacteria,42NWX@68525|delta/epsilon subdivisions,2YR28@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Adenine deaminase C-terminal domain	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
k59_92573_1	580332.Slit_2101	2.17e-83	259.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,2VJ29@28216|Betaproteobacteria,44VB5@713636|Nitrosomonadales	28216|Betaproteobacteria	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	algC	GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_984218_2	998674.ATTE01000001_gene3046	1.54e-50	171.0	COG1106@1|root,COG1106@2|Bacteria,1NER1@1224|Proteobacteria,1SFR8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21,ParBc
k59_1624573_1	1165841.SULAR_09854	1.13e-61	192.0	COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,42SVZ@68525|delta/epsilon subdivisions,2YPE3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the UPF0234 family	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
k59_1624584_1	1297865.APJD01000006_gene4448	4.21e-54	187.0	COG0515@1|root,COG0631@1|root,COG0515@2|Bacteria,COG0631@2|Bacteria,1MV1P@1224|Proteobacteria,2TQTS@28211|Alphaproteobacteria,3JQUJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	KLT	Serine/threonine phosphatases, family 2C, catalytic domain	MA20_17085	-	-	-	-	-	-	-	-	-	-	-	PP2C_2,Pkinase
k59_1742871_1	1304883.KI912532_gene623	1.09e-54	172.0	2C1YJ@1|root,32ZXK@2|Bacteria,1N98H@1224|Proteobacteria,2VVT5@28216|Betaproteobacteria,2KXDS@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF2782)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2782
k59_1742871_2	1304883.KI912532_gene624	3.66e-108	315.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,2VK4I@28216|Betaproteobacteria,2KUFM@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
k59_160485_1	1537917.JU82_06250	2.91e-124	368.0	COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,42N0P@68525|delta/epsilon subdivisions,2YN14@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	UPF0313 protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,Radical_SAM_N
k59_574992_1	159087.Daro_0917	1.42e-29	119.0	COG3034@1|root,COG3034@2|Bacteria,1N2B6@1224|Proteobacteria,2VJXB@28216|Betaproteobacteria,2KVPI@206389|Rhodocyclales	206389|Rhodocyclales	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
k59_574992_2	1500893.JQNB01000001_gene328	1.25e-05	49.7	COG0745@1|root,COG0745@2|Bacteria,1RD6H@1224|Proteobacteria,1S623@1236|Gammaproteobacteria,1X5ZG@135614|Xanthomonadales	135614|Xanthomonadales	KT	two-component system	YH67_17215	-	-	ko:K02485	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg
k59_693508_1	1249480.B649_05425	5.99e-128	374.0	COG0282@1|root,COG0282@2|Bacteria,1MW61@1224|Proteobacteria,42MJA@68525|delta/epsilon subdivisions,2YMX6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0903m	Acetate_kinase
k59_919975_2	929558.SMGD1_0379	1.57e-54	173.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	cheY40H-4	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
k59_859451_1	1502770.JQMG01000001_gene2248	7.23e-68	211.0	COG1309@1|root,COG1309@2|Bacteria,1N659@1224|Proteobacteria,2VS47@28216|Betaproteobacteria,2KM73@206350|Nitrosomonadales	206350|Nitrosomonadales	K	MAATS-type transcriptional repressor, C-terminal region	-	-	-	ko:K03577	-	M00647	-	-	ko00000,ko00002,ko03000	-	-	-	TetR_C_2,TetR_N
k59_1627720_1	266264.Rmet_4976	1.96e-89	263.0	COG2510@1|root,COG2510@2|Bacteria,1RJ4E@1224|Proteobacteria,2VS3K@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Psort location CytoplasmicMembrane, score 9.46	-	-	-	ko:K08978	-	-	-	-	ko00000,ko02000	2.A.7.2	-	-	EamA
k59_1627720_2	266264.Rmet_4977	4.8e-34	127.0	COG0642@1|root,COG2205@2|Bacteria,1N1Z2@1224|Proteobacteria,2VJBG@28216|Betaproteobacteria,1K3RW@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Histidine kinase	qseC	-	2.7.13.3	ko:K02484,ko:K07645	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_1392450_1	159087.Daro_0651	2.45e-28	110.0	28IJP@1|root,2Z8KI@2|Bacteria,1R9DP@1224|Proteobacteria,2VVJ7@28216|Betaproteobacteria,2KX2H@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1392450_2	640081.Dsui_1333	5.77e-17	76.6	COG1664@1|root,COG1664@2|Bacteria,1MZN0@1224|Proteobacteria,2VTZQ@28216|Betaproteobacteria,2KWWR@206389|Rhodocyclales	206389|Rhodocyclales	M	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
k59_808061_1	709032.Sulku_0959	1.47e-134	392.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42Z0P@68525|delta/epsilon subdivisions,2YR4F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG0513 Superfamily II DNA and RNA	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k59_1868130_1	159087.Daro_0912	2.04e-93	276.0	COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,2VRSR@28216|Betaproteobacteria,2KWDP@206389|Rhodocyclales	206389|Rhodocyclales	S	Predicted membrane protein (DUF2238)	-	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
k59_737385_1	929558.SMGD1_1144	1.05e-52	173.0	COG3038@1|root,COG3038@2|Bacteria,1NC3G@1224|Proteobacteria,42SCY@68525|delta/epsilon subdivisions,2YQ0N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
k59_219251_2	1537917.JU82_02205	1.67e-73	224.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,42NBY@68525|delta/epsilon subdivisions,2YMSY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Co-chaperone-curved DNA binding protein A	cbpA	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
k59_1801360_1	1537917.JU82_08515	4.95e-127	379.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,43BJ8@68525|delta/epsilon subdivisions,2YMMJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	penicillin-binding protein	pbpA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
k59_1458012_1	709032.Sulku_1383	1.59e-28	109.0	COG0007@1|root,COG0007@2|Bacteria,1MUI0@1224|Proteobacteria,42MCB@68525|delta/epsilon subdivisions,2YNRA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme	-	-	1.3.1.76,2.1.1.107,4.99.1.4	ko:K02302,ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03194,R03947	RC00003,RC00871,RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_7,Sirohm_synth_M,TP_methylase
k59_1458012_2	1249480.B649_07115	1.53e-83	265.0	COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,42PHY@68525|delta/epsilon subdivisions,2YMBI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG0155 Sulfite reductase, beta subunit (hemoprotein)	-	-	1.7.7.1,1.8.7.1	ko:K00366,ko:K00392	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00531	R00790,R00859,R03600	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
k59_329175_1	1249480.B649_06920	3.49e-97	292.0	COG0517@1|root,COG2199@1|root,COG0517@2|Bacteria,COG2199@2|Bacteria,1RGCV@1224|Proteobacteria,43DAF@68525|delta/epsilon subdivisions,2YTHJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG2199 FOG GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GGDEF
k59_1458014_1	338969.Rfer_1608	6.11e-46	150.0	COG5572@1|root,COG5572@2|Bacteria,1MZ6Q@1224|Proteobacteria,2VV7D@28216|Betaproteobacteria,4AF57@80864|Comamonadaceae	28216|Betaproteobacteria	S	Predicted integral membrane protein (DUF2282)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2282
k59_1458014_2	1470593.BW43_05396	1.65e-18	83.6	COG3220@1|root,COG3220@2|Bacteria,1MURE@1224|Proteobacteria,1RQ9H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the UPF0276 family	-	-	-	ko:K09930	-	-	-	-	ko00000	-	-	-	DUF692
k59_94934_1	709032.Sulku_2255	1.8e-54	177.0	COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,42N66@68525|delta/epsilon subdivisions,2YMY7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate	ate	-	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	ATE_C,ATE_N
k59_749785_2	1123517.JOMR01000001_gene1766	3.14e-112	331.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,1RQ72@1236|Gammaproteobacteria,460HI@72273|Thiotrichales	72273|Thiotrichales	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxC
k59_1405429_1	387093.SUN_1475	4.99e-138	404.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2YMB5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	abc transporter atp-binding protein	yheS	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
k59_1345168_1	1165841.SULAR_05543	6.64e-56	191.0	COG0642@1|root,COG4564@1|root,COG0642@2|Bacteria,COG4564@2|Bacteria,1QZ2C@1224|Proteobacteria,42QBR@68525|delta/epsilon subdivisions,2YNQB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_2,sCache_2
k59_1113046_1	1122201.AUAZ01000010_gene2562	3.32e-61	192.0	COG0716@1|root,COG0716@2|Bacteria,1MX7F@1224|Proteobacteria,1RMNT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Low-potential electron donor to a number of redox enzymes	nifF	-	-	ko:K03839	-	-	-	-	ko00000	-	-	-	Flavodoxin_1
k59_1345174_1	1249480.B649_08390	3.88e-103	304.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,42M98@68525|delta/epsilon subdivisions,2YPXH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
k59_821748_1	1538644.KO02_09600	5.33e-08	58.5	COG2207@1|root,COG2207@2|Bacteria,4NHYH@976|Bacteroidetes,1IPGH@117747|Sphingobacteriia	976|Bacteroidetes	K	PFAM helix-turn-helix- domain containing protein AraC type	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
k59_1813434_1	1537917.JU82_09450	1.1e-105	311.0	COG2996@1|root,COG2996@2|Bacteria,1MXC3@1224|Proteobacteria,42P2A@68525|delta/epsilon subdivisions,2YMVD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	S1 domain	-	-	-	ko:K00243	-	-	-	-	ko00000	-	-	-	S1_2
k59_527198_1	1121935.AQXX01000138_gene3144	5.41e-27	115.0	COG0642@1|root,COG3452@1|root,COG2205@2|Bacteria,COG3452@2|Bacteria,1NRP8@1224|Proteobacteria,1T44K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	signal transduction Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_343089_1	709032.Sulku_1898	9.65e-113	329.0	28M05@1|root,2ZAF9@2|Bacteria,1MY5U@1224|Proteobacteria,42MJP@68525|delta/epsilon subdivisions,2YMVI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	General glycosylation pathway protein	pglG	-	-	-	-	-	-	-	-	-	-	-	dCache_1
k59_230298_1	159087.Daro_1952	7.5e-67	203.0	COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,2VSKY@28216|Betaproteobacteria,2KWP9@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the HesB IscA family	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
k59_230298_2	1000565.METUNv1_00563	1.63e-77	232.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,2VQ2I@28216|Betaproteobacteria,2KWB3@206389|Rhodocyclales	206389|Rhodocyclales	C	A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
k59_230298_3	688245.CtCNB1_2733	9.72e-11	61.2	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,2VH91@28216|Betaproteobacteria,4AABE@80864|Comamonadaceae	28216|Betaproteobacteria	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
k59_874509_1	1437824.BN940_15786	3.62e-38	147.0	COG1262@1|root,COG1352@1|root,COG1262@2|Bacteria,COG1352@2|Bacteria,1MUNC@1224|Proteobacteria,2VH4V@28216|Betaproteobacteria,3T3DF@506|Alcaligenaceae	28216|Betaproteobacteria	NT	DinB superfamily	egtB	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase
k59_1522351_1	1249480.B649_07775	2.58e-97	296.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2YM8S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
k59_289783_1	1304883.KI912532_gene511	1.41e-92	281.0	COG0116@1|root,COG0116@2|Bacteria,1MUQM@1224|Proteobacteria,2VHMY@28216|Betaproteobacteria,2KV05@206389|Rhodocyclales	206389|Rhodocyclales	L	Belongs to the methyltransferase superfamily	-	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
k59_1813508_1	1537917.JU82_01985	1.25e-236	656.0	COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2YMD8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	porA	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
k59_1230898_1	1304883.KI912532_gene1019	1.42e-102	315.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2VH59@28216|Betaproteobacteria,2KVJZ@206389|Rhodocyclales	206389|Rhodocyclales	I	carboxylase	pccA	-	6.4.1.3	ko:K01965	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
k59_1347524_1	709032.Sulku_1524	5.32e-98	305.0	COG0659@1|root,COG0664@1|root,COG0659@2|Bacteria,COG0664@2|Bacteria,1MVWV@1224|Proteobacteria,42MMU@68525|delta/epsilon subdivisions,2YTMR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	STAS domain	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp,cNMP_binding
k59_291499_1	1038867.AXAY01000005_gene7217	2.13e-33	131.0	COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,3JVPA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF
k59_467623_1	1249480.B649_04030	8.61e-69	222.0	COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,4302Q@68525|delta/epsilon subdivisions,2YRWT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
k59_1408299_1	1249480.B649_01065	2.78e-112	328.0	COG2214@1|root,COG2214@2|Bacteria,1QV0K@1224|Proteobacteria,42RGB@68525|delta/epsilon subdivisions	1224|Proteobacteria	O	DnaJ domain protein	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ
k59_876867_1	1268072.PSAB_12900	1.56e-102	330.0	COG0243@1|root,COG0369@1|root,COG0243@2|Bacteria,COG0369@2|Bacteria,1VTS0@1239|Firmicutes,4HAZ4@91061|Bacilli,26RIP@186822|Paenibacillaceae	91061|Bacilli	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.8.1.2	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_1,Flavodoxin_1,LysM,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NAD_binding_1
k59_1408330_1	377629.TERTU_3358	4.09e-10	60.1	COG2010@1|root,COG2010@2|Bacteria,1NG71@1224|Proteobacteria,1RNZA@1236|Gammaproteobacteria,2PQ8W@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1408330_2	1168067.JAGP01000001_gene1536	5.11e-50	177.0	COG3211@1|root,COG3211@2|Bacteria,1MU8T@1224|Proteobacteria,1RSM7@1236|Gammaproteobacteria,461T0@72273|Thiotrichales	72273|Thiotrichales	S	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
k59_467678_1	709032.Sulku_2450	8.03e-118	367.0	COG0517@1|root,COG2202@1|root,COG5001@1|root,COG0517@2|Bacteria,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YMHP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF,PAS_4
k59_467678_2	1249480.B649_11365	5.88e-15	73.9	COG0517@1|root,COG2199@1|root,COG0517@2|Bacteria,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42SZE@68525|delta/epsilon subdivisions,2YR4N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GGDEF
k59_232538_1	90814.KL370891_gene93	1.24e-71	231.0	COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,1RMDI@1236|Gammaproteobacteria,4601I@72273|Thiotrichales	72273|Thiotrichales	C	TIGRFAM cytochrome c oxidase accessory protein FixG	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
k59_345718_1	1249480.B649_02490	1.26e-45	147.0	COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,42V30@68525|delta/epsilon subdivisions,2YPWV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
k59_345718_2	709032.Sulku_0497	6.6e-42	138.0	COG1837@1|root,COG1837@2|Bacteria,1N7IX@1224|Proteobacteria,42VEW@68525|delta/epsilon subdivisions,2YQ7J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	RNA-binding protein	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
k59_345718_3	709032.Sulku_0498	1.26e-36	128.0	COG0806@1|root,COG0806@2|Bacteria,1MYUH@1224|Proteobacteria,42SEN@68525|delta/epsilon subdivisions,2YPH6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
k59_467732_1	159087.Daro_3566	4.94e-76	231.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,2VI2C@28216|Betaproteobacteria,2KVV2@206389|Rhodocyclales	206389|Rhodocyclales	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
k59_467734_2	1537917.JU82_07035	1.72e-73	232.0	COG1168@1|root,COG1168@2|Bacteria,1MY33@1224|Proteobacteria,42M6F@68525|delta/epsilon subdivisions,2YMXE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Aminotransferase, class I	patB	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_1231014_1	159087.Daro_4114	1.7e-38	139.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,2VHDZ@28216|Betaproteobacteria,2KUDB@206389|Rhodocyclales	206389|Rhodocyclales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
k59_1231014_2	159087.Daro_4115	4.46e-87	257.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,2VR2R@28216|Betaproteobacteria,2KWEP@206389|Rhodocyclales	206389|Rhodocyclales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
k59_752422_1	709032.Sulku_1467	4.14e-73	232.0	COG0642@1|root,COG5000@1|root,COG0642@2|Bacteria,COG5000@2|Bacteria,1N5IQ@1224|Proteobacteria,42N7Z@68525|delta/epsilon subdivisions,2YN64@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
k59_345778_1	640081.Dsui_3086	6.8e-28	115.0	COG3034@1|root,COG3034@2|Bacteria,1N2B6@1224|Proteobacteria,2VJXB@28216|Betaproteobacteria,2KVPI@206389|Rhodocyclales	206389|Rhodocyclales	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
k59_1408477_1	1123326.JFBL01000002_gene1759	4.95e-41	145.0	COG0834@1|root,COG0834@2|Bacteria,1RDJ0@1224|Proteobacteria,4315G@68525|delta/epsilon subdivisions	1224|Proteobacteria	ET	Bacterial extracellular solute-binding proteins, family 3	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_3
k59_467867_1	709032.Sulku_0004	1.31e-59	197.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1RGCV@1224|Proteobacteria,42M47@68525|delta/epsilon subdivisions,2YMRS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	(EAL) domain protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_109284_1	1485544.JQKP01000011_gene754	4.61e-20	94.7	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,44W78@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S)	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3
k59_467890_1	1537917.JU82_09970	3.02e-153	440.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,42MQ3@68525|delta/epsilon subdivisions,2YMPC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
k59_1231121_1	395494.Galf_1546	9.46e-78	241.0	COG1879@1|root,COG1879@2|Bacteria,1MXJS@1224|Proteobacteria,2VJJZ@28216|Betaproteobacteria	28216|Betaproteobacteria	G	PFAM Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
k59_406673_1	1123517.JOMR01000001_gene165	2.66e-177	512.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RR00@1236|Gammaproteobacteria,461XN@72273|Thiotrichales	72273|Thiotrichales	EH	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_1347752_1	497321.C664_06758	5.38e-50	168.0	COG0348@1|root,COG0348@2|Bacteria,1MUWD@1224|Proteobacteria,2VMUP@28216|Betaproteobacteria,2KUX9@206389|Rhodocyclales	206389|Rhodocyclales	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
k59_1347752_2	85643.Tmz1t_2602	2.99e-66	209.0	COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,2VHWI@28216|Betaproteobacteria,2KUMP@206389|Rhodocyclales	206389|Rhodocyclales	S	COG0714 MoxR-like ATPases	norQ	-	-	ko:K04748	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	AAA_5,CbbQ_C
k59_406753_1	289376.THEYE_A0296	1.14e-23	105.0	COG3505@1|root,COG3505@2|Bacteria,3J18N@40117|Nitrospirae	40117|Nitrospirae	U	Type IV secretion-system coupling protein DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	TrwB_AAD_bind
k59_752585_1	159087.Daro_1051	1.53e-178	518.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VH8J@28216|Betaproteobacteria,2KU93@206389|Rhodocyclales	206389|Rhodocyclales	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copA	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
k59_232776_1	572480.Arnit_1858	2.45e-38	135.0	COG0745@1|root,COG0745@2|Bacteria,1N7TJ@1224|Proteobacteria,42SSI@68525|delta/epsilon subdivisions,2YPDF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_232776_2	709032.Sulku_2077	6.95e-148	422.0	COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,42ND2@68525|delta/epsilon subdivisions,2YMQ0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_2
k59_468125_1	583345.Mmol_1617	3.33e-82	249.0	2C8XG@1|root,2Z7PK@2|Bacteria,1RA5I@1224|Proteobacteria,2VQGY@28216|Betaproteobacteria,2KKNU@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
k59_1408704_1	1537917.JU82_11855	8.78e-11	61.2	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,42MRQ@68525|delta/epsilon subdivisions,2YMJY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1g
k59_1408704_2	563040.Saut_0585	9.46e-103	310.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,42M2H@68525|delta/epsilon subdivisions,2YMM9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k59_468214_2	1121439.dsat_0648	3.13e-15	80.5	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,43BN0@68525|delta/epsilon subdivisions,2X702@28221|Deltaproteobacteria,2M8FC@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,HATPase_c,HisKA,PAS_4,PAS_9,Response_reg
k59_468228_1	1249480.B649_07120	2.1e-96	297.0	COG0437@1|root,COG3302@1|root,COG0437@2|Bacteria,COG3302@2|Bacteria,1MU1B@1224|Proteobacteria,42QHG@68525|delta/epsilon subdivisions,2YN5C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K07307	ko00920,map00920	-	R09501	RC02555	ko00000,ko00001,ko02000	5.A.3.3	-	-	DmsC,Fer4_11,Fer4_4
k59_752658_1	709032.Sulku_2355	7.3e-161	458.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,42M9E@68525|delta/epsilon subdivisions,2YMCM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
k59_877206_1	159087.Daro_0855	7.76e-85	258.0	COG0731@1|root,COG0731@2|Bacteria,1QG36@1224|Proteobacteria,2VK7Z@28216|Betaproteobacteria,2KVBZ@206389|Rhodocyclales	206389|Rhodocyclales	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_232847_2	1249480.B649_10875	1.22e-40	140.0	COG1385@1|root,COG1385@2|Bacteria,1QDSD@1224|Proteobacteria,42S1W@68525|delta/epsilon subdivisions,2YP9M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
k59_752681_1	1537917.JU82_08525	6.69e-172	496.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,42MFA@68525|delta/epsilon subdivisions,2YMUE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
k59_468274_1	1304883.KI912532_gene47	7.74e-148	433.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,2VH14@28216|Betaproteobacteria,2KVAY@206389|Rhodocyclales	206389|Rhodocyclales	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
k59_1701200_1	1122603.ATVI01000006_gene285	2.86e-11	60.1	2B3E9@1|root,31W34@2|Bacteria,1MZ95@1224|Proteobacteria,1SA6A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1701200_2	1235279.C772_02983	2.16e-51	166.0	COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,4HKEF@91061|Bacilli,26FEZ@186818|Planococcaceae	91061|Bacilli	J	Endoribonuclease L-PSP	yabJ	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019239,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046360,GO:0046361,GO:0046394,GO:0046459,GO:0051790,GO:0071704,GO:0072330,GO:1901576	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
k59_1701200_3	387093.SUN_1784	1.34e-60	187.0	COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,42SGM@68525|delta/epsilon subdivisions,2YPJ3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
k59_1701200_4	1165841.SULAR_05768	9.8e-15	67.8	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,42THK@68525|delta/epsilon subdivisions,2YQ0A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
k59_1347931_1	367737.Abu_0678	5.28e-60	204.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,42MEI@68525|delta/epsilon subdivisions,2YND5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	asparagine	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_468335_1	1249480.B649_05370	4.56e-63	214.0	COG1449@1|root,COG1449@2|Bacteria,1P2YJ@1224|Proteobacteria,42N8E@68525|delta/epsilon subdivisions,2YNF0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
k59_1524288_1	1249480.B649_01765	2.98e-187	528.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,42ME0@68525|delta/epsilon subdivisions,2YMC8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_232909_1	709032.Sulku_2269	3.37e-264	765.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2YMP9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5,RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_1408820_1	78245.Xaut_3664	2.93e-26	113.0	2CYA9@1|root,32T3V@2|Bacteria,1RGRN@1224|Proteobacteria,2U90D@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_468436_1	525897.Dbac_1136	6.57e-61	199.0	COG0158@1|root,COG0158@2|Bacteria,1MW0E@1224|Proteobacteria,42NRA@68525|delta/epsilon subdivisions,2WJ62@28221|Deltaproteobacteria,2M7YJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1	fbp	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
k59_346151_1	94122.Shewana3_0129	2.2e-51	169.0	COG0670@1|root,COG0670@2|Bacteria,1MVGU@1224|Proteobacteria,1RNKB@1236|Gammaproteobacteria,2Q8Z5@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Belongs to the BI1 family	-	-	-	ko:K06890	-	-	-	-	ko00000	-	-	-	Bax1-I
k59_1347992_1	760154.Sulba_2445	2.08e-49	166.0	COG3980@1|root,COG3980@2|Bacteria,1Q330@1224|Proteobacteria,42P4J@68525|delta/epsilon subdivisions,2YMEH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	pseudaminic acid biosynthesis-associated protein PseG	pseG	-	3.6.1.57	ko:K15897	ko00520,map00520	-	R09834	RC00005,RC00078	ko00000,ko00001,ko01000	-	-	-	Glyco_tran_28_C
k59_1347992_2	1249480.B649_00705	1.2e-35	126.0	COG1083@1|root,COG1083@2|Bacteria,1QACI@1224|Proteobacteria,42QBP@68525|delta/epsilon subdivisions,2YNAX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	CMP-N-acetylneuraminic acid synthetase	pseF	-	2.7.7.43,2.7.7.81	ko:K00983,ko:K15899	ko00520,ko01100,map00520,map01100	-	R01117,R04215,R09843	RC00152	ko00000,ko00001,ko01000	-	-	-	CTP_transf_3
k59_468446_2	1454004.AW11_00651	2.23e-54	179.0	COG2354@1|root,COG2354@2|Bacteria,1MVYU@1224|Proteobacteria,2VHTU@28216|Betaproteobacteria	28216|Betaproteobacteria	S	protein conserved in bacteria	yedI	-	-	ko:K09781	-	-	-	-	ko00000	-	-	-	DUF808
k59_291888_1	1442598.JABW01000031_gene1296	1.9e-21	98.2	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,43BRF@68525|delta/epsilon subdivisions,2YNGV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	TonB dependent receptor	-	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
k59_752795_1	305700.B447_01326	2e-12	65.1	COG1028@1|root,COG1028@2|Bacteria,1MUEV@1224|Proteobacteria,2VH8R@28216|Betaproteobacteria,2KVKX@206389|Rhodocyclales	206389|Rhodocyclales	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	1.1.1.36	ko:K00023	ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200	M00373	R01779,R01977	RC00103,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short,adh_short_C2
k59_752795_2	159087.Daro_1608	2.79e-189	539.0	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,2VH50@28216|Betaproteobacteria,2KUWX@206389|Rhodocyclales	206389|Rhodocyclales	I	Poly(R)-hydroxyalkanoic acid synthase, class I	-	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	PhaC_N
k59_406973_2	1537917.JU82_01115	9.35e-79	240.0	COG0788@1|root,COG0788@2|Bacteria,1MVCF@1224|Proteobacteria,42MPM@68525|delta/epsilon subdivisions,2YMX5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT,Formyl_trans_N
k59_346187_1	1249480.B649_07200	5.33e-56	183.0	COG2301@1|root,COG2301@2|Bacteria,1NUDQ@1224|Proteobacteria,42QUW@68525|delta/epsilon subdivisions,2YNZV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the HpcH HpaI aldolase family	citE	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
k59_346187_2	1249480.B649_07205	2.11e-66	203.0	COG2010@1|root,COG2010@2|Bacteria,1Q2E5@1224|Proteobacteria,42VHQ@68525|delta/epsilon subdivisions,2YQ7N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
k59_468540_1	795666.MW7_1734	4.31e-19	85.9	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2VH5A@28216|Betaproteobacteria,1K0RZ@119060|Burkholderiaceae	28216|Betaproteobacteria	C	PFAM FAD linked oxidase domain protein	glcD2	-	1.1.2.4	ko:K00102	ko00620,map00620	-	R00197	RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
k59_468540_2	395494.Galf_1660	2.54e-85	259.0	COG0289@1|root,COG0289@2|Bacteria,1RAV8@1224|Proteobacteria,2VZHT@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Dihydrodipicolinate reductase, C-terminus	-	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
k59_346212_1	1123487.KB892867_gene996	6.52e-42	147.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,2VHBD@28216|Betaproteobacteria,2KVKQ@206389|Rhodocyclales	206389|Rhodocyclales	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_1231508_1	709032.Sulku_2261	3.71e-102	307.0	COG0845@1|root,COG0845@2|Bacteria,1QMYR@1224|Proteobacteria,42WWX@68525|delta/epsilon subdivisions,2YR01@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	RND family efflux transporter, MFP subunit	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
k59_1231508_2	1537917.JU82_02050	2.67e-23	98.6	COG1538@1|root,COG1538@2|Bacteria,1Q5X2@1224|Proteobacteria,43200@68525|delta/epsilon subdivisions,2YS78@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_1816141_3	1197951.I6S2A3_9CAUD	3.68e-35	132.0	4QAIV@10239|Viruses,4QYFZ@35237|dsDNA viruses  no RNA stage,4QQUY@28883|Caudovirales	28883|Caudovirales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
## 12515 queries scanned
## Total time (seconds): 98.72971034049988
## Rate: 126.76 q/s