## Sat Jan 4 12:07:06 2025 ## emapper-2.1.12 ## /data/home/zhuyingjie/miniforge3/envs/eggnog/bin/emapper.py -i /data/home/zhuyingjie/01_Project/01_metagenome/mangrove/mmseqs_cluster/PRJNA437562/SRR6820481/SRR6820481_p_cluster_rep_seq.fasta --output PRJNA437562_SRR6820481 --data_dir /data/software/eggnog_database -m diamond --sensmode fast --output_dir /data/home/zhuyingjie/01_Project/01_metagenome/mangrove/annotation --temp_dir /data/software/eggnog_database/temp --excel --dbmem --cpu 24 ## #query seed_ortholog evalue score eggNOG_OGs max_annot_lvl COG_category Description Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction PFAMs k59_596016_3 1042209.HK44_029890 6.24e-32 125.0 28H9R@1|root,2Z7MD@2|Bacteria,1MVTR@1224|Proteobacteria,1RMPH@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Psort location Cytoplasmic, score 8.96 yfjQ - - - - - - - - - - - DUF932 k59_596016_4 679197.HMPREF9336_00431 1.01e-14 85.9 COG3378@1|root,COG3378@2|Bacteria,2GQQM@201174|Actinobacteria 201174|Actinobacteria S Phage plasmid primase P4 family - - - - - - - - - - - - D5_N k59_596016_6 1204521.I7A8M4_9CAUD 2.26e-62 205.0 4QCW5@10239|Viruses,4QWI1@35237|dsDNA viruses no RNA stage,4QQVP@28883|Caudovirales,4QHUS@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_596016_10 573174.M4MA40_9VIRU 4.93e-14 68.6 4QC2V@10239|Viruses,4QUQ5@35237|dsDNA viruses no RNA stage 10239|Viruses S Superinfection immunity protein - - - - - - - - - - - - - k59_596016_11 1353529.M899_2142 1.23e-07 59.7 COG3091@1|root,COG3091@2|Bacteria,1R1VA@1224|Proteobacteria,43DBF@68525|delta/epsilon subdivisions,2X8HF@28221|Deltaproteobacteria 28221|Deltaproteobacteria S SprT-like family - - - - - - - - - - - - DUF2786,SprT-like k59_186109_2 691965.D4P7H8_9CAUD 3.01e-56 185.0 4QG1E@10239|Viruses,4QZE1@35237|dsDNA viruses no RNA stage,4QU6Q@28883|Caudovirales,4QMKH@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_145054_1 1379719.S5TMX6_9CIRC 1.06e-50 180.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_165467_2 492774.JQMB01000002_gene1077 2.3e-76 235.0 COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,2TU7F@28211|Alphaproteobacteria,4B6Y5@82115|Rhizobiaceae 28211|Alphaproteobacteria F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) queC - 6.3.4.20 ko:K06920 ko00790,ko01100,map00790,map01100 - R09978 RC00959 ko00000,ko00001,ko01000,ko03016 - - - QueC k59_514568_2 269482.Bcep1808_1155 9.14e-43 150.0 2DM17@1|root,319VU@2|Bacteria,1R6RI@1224|Proteobacteria,2WG8E@28216|Betaproteobacteria,1KIBI@119060|Burkholderiaceae 28216|Betaproteobacteria L PFAM GIY-YIG catalytic domain - - - - - - - - - - - - - k59_452855_1 691965.D4P7L3_9CAUD 7.87e-146 431.0 4QBH7@10239|Viruses,4QWWF@35237|dsDNA viruses no RNA stage,4QQ8R@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_370547_1 585198.HMPREF0574_1043 3.19e-22 102.0 COG2887@1|root,COG2887@2|Bacteria,2IBBB@201174|Actinobacteria,4D5D6@85005|Actinomycetales 201174|Actinobacteria L Protein of unknown function (DUF2800) - - - - - - - - - - - - DUF2800 k59_637562_2 367336.OM2255_09016 6.61e-17 79.7 COG2189@1|root,COG2189@2|Bacteria,1MX9M@1224|Proteobacteria,2TSW9@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the N(4) N(6)-methyltransferase family ccrM - 2.1.1.72 ko:K13581 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko02048 - - - N6_N4_Mtase k59_124433_5 1540823.A0A088FC23_9CAUD 6.64e-22 100.0 4QC5D@10239|Viruses,4QPVU@28883|Caudovirales,4QM4F@10699|Siphoviridae 10699|Siphoviridae S Protein of unknown function (DUF2800) - - - - - - - - - - - - - k59_411975_2 1217714.F975_02344 6.98e-62 204.0 28HEE@1|root,2Z7QU@2|Bacteria,1MXU6@1224|Proteobacteria,1RZSJ@1236|Gammaproteobacteria,3NJ4Z@468|Moraxellaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF932) - - - - - - - - - - - - DUF932 k59_330366_7 926562.Oweho_2253 2.15e-06 57.8 COG4409@1|root,COG4409@2|Bacteria 2|Bacteria G exo-alpha-(2->6)-sialidase activity - - - - - - - - - - - - BNR_2,Gram_pos_anchor k59_65736_2 1151122.AQYD01000006_gene1759 0.000194 49.3 COG4733@1|root,COG4733@2|Bacteria,2GMKC@201174|Actinobacteria,4FKWD@85023|Microbacteriaceae 201174|Actinobacteria S Fibronectin type 3 domain - - - - - - - - - - - - - k59_557768_1 1121459.AQXE01000001_gene2737 4.36e-70 221.0 2EMTV@1|root,33FG7@2|Bacteria 2|Bacteria S Gene 88 protein - - - - - - - - - - - - GP88 k59_24575_1 313612.L8106_24385 2.56e-13 74.7 COG0675@1|root,COG0675@2|Bacteria,1G10J@1117|Cyanobacteria,1H8Q7@1150|Oscillatoriales 1117|Cyanobacteria L COG0675 Transposase and inactivated derivatives - - - ko:K07496 - - - - ko00000 - - - OrfB_IS605,OrfB_Zn_ribbon k59_270792_1 1121344.JHZO01000006_gene1818 1.51e-28 111.0 28MKK@1|root,2ZAWR@2|Bacteria,1UYAT@1239|Firmicutes,24GI2@186801|Clostridia,3WR2E@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - RNA_helicase,Viral_Rep k59_147961_2 216816.GS08_06960 2.4e-21 99.8 COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4CZKT@85004|Bifidobacteriales 201174|Actinobacteria L DNA polymerase III alpha subunit dnaE GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k59_414427_2 1157708.KB907450_gene5419 1.2e-20 89.4 2EB1Y@1|root,3352R@2|Bacteria,1NASI@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_291451_1 717606.PaecuDRAFT_1527 2.52e-24 103.0 COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,4HBXF@91061|Bacilli,26SEN@186822|Paenibacillaceae 91061|Bacilli M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose spsK - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind k59_456583_2 1453500.AT05_10735 0.000161 50.4 COG2908@1|root,COG2908@2|Bacteria,4NFD8@976|Bacteroidetes,1HY0C@117743|Flavobacteriia 976|Bacteroidetes S Phosphoesterase - - - - - - - - - - - - Metallophos,Metallophos_2 k59_478091_3 105154.Q9MBU6_9VIRU 5e-182 530.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_478091_5 1165094.RINTHH_3920 1.16e-50 176.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_271202_2 1498011.A0A096XUY1_9CAUD 1.72e-46 164.0 4QHBE@10239|Viruses,4QT2W@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_25027_1 1408321.JNJD01000012_gene2287 3.12e-19 88.6 COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,2484K@186801|Clostridia,27IH7@186928|unclassified Lachnospiraceae 186801|Clostridia M Belongs to the MurCDEF family murC - - - - - - - - - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k59_414875_2 469660.A8HNW8_9CAUD 1.04e-44 153.0 4QHKD@10239|Viruses,4R09W@35237|dsDNA viruses no RNA stage,4QQVX@28883|Caudovirales,4QNWT@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_599330_1 691965.D4P7I3_9CAUD 1.76e-29 120.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_599330_3 691965.D4P7I8_9CAUD 1.49e-52 172.0 4QGJH@10239|Viruses,4QZ35@35237|dsDNA viruses no RNA stage,4QRZS@28883|Caudovirales,4QMAA@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_478141_1 1038860.AXAP01000015_gene2006 5.14e-42 153.0 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,2U6BJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S TIGRFAM phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_127951_1 420662.Mpe_B0284 6.44e-13 65.5 COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,2VQ5I@28216|Betaproteobacteria 1224|Proteobacteria F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA - - 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase k59_456610_1 981335.G4W934_9CAUD 6.49e-37 135.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales 28883|Caudovirales S N-methyltransferase activity - - - - - - - - - - - - - k59_478145_2 360094.PXO_01340 0.000291 46.6 COG5283@1|root,COG5412@1|root,COG5283@2|Bacteria,COG5412@2|Bacteria,1NFKU@1224|Proteobacteria,1RP2D@1236|Gammaproteobacteria,1X7F9@135614|Xanthomonadales 135614|Xanthomonadales S Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_251444_1 1444309.JAQG01000013_gene1929 8.96e-59 194.0 29YKT@1|root,30KG4@2|Bacteria,1UNWA@1239|Firmicutes,4IUSF@91061|Bacilli,2721K@186822|Paenibacillaceae 91061|Bacilli S RecT family - - - - - - - - - - - - RecT k59_478175_1 68199.JNZO01000002_gene1396 4.67e-25 109.0 COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria 201174|Actinobacteria V ABC transporter - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k59_28513_1 863365.XHC_0698 1.64e-09 56.2 COG1426@1|root,COG1426@2|Bacteria,1R1FD@1224|Proteobacteria,1T50M@1236|Gammaproteobacteria,1XB6W@135614|Xanthomonadales 135614|Xanthomonadales K Helix-turn-helix domain - - - - - - - - - - - - HTH_31 k59_28513_2 266779.Meso_1199 4.62e-94 298.0 COG0553@1|root,COG0553@2|Bacteria,1R7CK@1224|Proteobacteria,2U228@28211|Alphaproteobacteria,43I7K@69277|Phyllobacteriaceae 28211|Alphaproteobacteria KL DEAD-like helicases superfamily - - - - - - - - - - - - Helicase_C,N6_N4_Mtase k59_483111_2 691965.D4P7C3_9CAUD 6.84e-42 141.0 4QDCX@10239|Viruses,4R0GS@35237|dsDNA viruses no RNA stage,4QS3P@28883|Caudovirales,4QKU8@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_92131_1 1095743.HMPREF1054_2026 1.61e-18 89.7 COG5185@1|root,COG5281@1|root,COG5185@2|Bacteria,COG5281@2|Bacteria 2|Bacteria D sister chromatid segregation - - 3.2.1.18 ko:K01186,ko:K21471,ko:K22051 ko00511,ko00600,ko04142,map00511,map00600,map04142 - R04018 RC00028,RC00077 ko00000,ko00001,ko01000,ko01002,ko01011,ko02000,ko02042 1.A.23.1.2,1.A.23.1.3 GH33 - Phage_HK97_TLTM k59_28528_2 1410612.JNKO01000045_gene2218 0.000804 41.2 COG3780@1|root,COG3780@2|Bacteria,1V8Q2@1239|Firmicutes,25GNQ@186801|Clostridia,2PTH5@265975|Oribacterium 186801|Clostridia L Cro/C1-type HTH DNA-binding domain - - - - - - - - - - - - HTH_3 k59_70006_1 1038860.AXAP01000067_gene8427 5.44e-21 96.7 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,2U6BJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S TIGRFAM phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_254976_2 1419711.U6BML2_9CIRC 1.22e-19 94.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_397702_1 118168.MC7420_4218 1.89e-10 65.9 28HEE@1|root,2Z7QU@2|Bacteria,1GB7S@1117|Cyanobacteria 1117|Cyanobacteria S Domain of unknown function (DUF932) - - - - - - - - - - - - DUF932 k59_233231_1 1453501.JELR01000001_gene2531 4.03e-72 237.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,1RP8Z@1236|Gammaproteobacteria,467QB@72275|Alteromonadaceae 1236|Gammaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_377576_1 1385658.U5KPZ6_9VIRU 7.78e-62 207.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_418636_1 1618237.A0A0C5IMG6_9CIRC 6.62e-13 70.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_441071_1 452652.KSE_60110 1.7e-06 58.2 COG3170@1|root,COG3291@1|root,COG3170@2|Bacteria,COG3291@2|Bacteria,2GKNE@201174|Actinobacteria,2M2FF@2063|Kitasatospora 201174|Actinobacteria NU Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - 3.4.24.3 ko:K01387 - - - - ko00000,ko01000,ko01002,ko02042 - - - PKD,PPC,Peptidase_M9,Peptidase_M9_N k59_460213_1 1538804.A0A088F6T3_9CAUD 1.65e-61 210.0 4QAKM@10239|Viruses,4QPEF@28883|Caudovirales,4QKNE@10699|Siphoviridae 10699|Siphoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_48227_1 768671.ThimaDRAFT_0726 5.87e-12 73.6 COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,1RXX2@1236|Gammaproteobacteria,1WX24@135613|Chromatiales 135613|Chromatiales S VWA-like domain (DUF2201) - - - - - - - - - - - - DUF2201,DUF2201_N k59_193151_1 1692244.A0A0K1RLR5_9CIRC 1.23e-48 169.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_544540_1 1121100.JCM6294_1078 8.95e-15 72.8 COG0863@1|root,COG0863@2|Bacteria 2|Bacteria L N-4 methylation of cytosine - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_356192_1 1121448.DGI_2056 2.99e-09 62.4 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,42QKN@68525|delta/epsilon subdivisions,2WK3R@28221|Deltaproteobacteria,2MA6M@213115|Desulfovibrionales 28221|Deltaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_462822_1 1548905.A0A0A1IUL8_9CAUD 9.51e-66 216.0 4QBA2@10239|Viruses,4QPPI@28883|Caudovirales,4QM0B@10699|Siphoviridae 10699|Siphoviridae S Thymidylate synthase - GO:0003674,GO:0003824,GO:0004799,GO:0008150,GO:0008152,GO:0008168,GO:0016740,GO:0016741,GO:0032259,GO:0042083 - - - - - - - - - - - k59_584909_1 212035.YR563_MIMIV 6.21e-10 67.8 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage 10239|Viruses S N-methyltransferase activity - GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0097159,GO:1901363 - - - - - - - - - - - k59_421141_1 1283300.ATXB01000001_gene198 7.96e-11 72.4 COG0582@1|root,COG0582@2|Bacteria,1N2H9@1224|Proteobacteria,1RYEY@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Belongs to the 'phage' integrase family intF GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0050896 - - - - - - - - - - Arm-DNA-bind_3,Phage_integrase k59_526962_1 1206735.BAGG01000011_gene584 2.92e-17 84.3 COG0270@1|root,COG0270@2|Bacteria,2GNB2@201174|Actinobacteria,4G2GK@85025|Nocardiaceae 201174|Actinobacteria L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_650810_2 999541.bgla_1g10950 1.72e-12 69.7 2C095@1|root,32VKM@2|Bacteria,1N0Y9@1224|Proteobacteria,2VUZF@28216|Betaproteobacteria,1KEDA@119060|Burkholderiaceae 28216|Betaproteobacteria S Domain of unknown function (DUF1833) - - - - - - - - - - - - DUF1833 k59_650810_3 272942.RCAP_rcc02911 3.08e-13 71.6 COG1511@1|root,COG5281@1|root,COG1511@2|Bacteria,COG5281@2|Bacteria 2|Bacteria D sister chromatid segregation - - - - - - - - - - - - Peptidase_M23,PhageMin_Tail,Phage_HK97_TLTM,TMP_2,Tape_meas_lam_C k59_30935_1 691965.D4P7E6_9CAUD 8.29e-06 53.5 4QAK6@10239|Viruses,4R01K@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_527678_1 445970.ALIPUT_02667 2.81e-72 232.0 2BKC5@1|root,32ESM@2|Bacteria,4PAIX@976|Bacteroidetes,2FX36@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_605883_1 31535.Q9XJT6_BPD3 3.84e-33 130.0 4QBV3@10239|Viruses,4QW0W@35237|dsDNA viruses no RNA stage,4QPPJ@28883|Caudovirales,4QKW5@10699|Siphoviridae 10699|Siphoviridae S Phage Terminase - - - - - - - - - - - - - k59_487224_1 1123321.KB905821_gene4276 9.3e-17 85.5 COG2369@1|root,COG2369@2|Bacteria 2|Bacteria K cell adhesion yqbB3 - - - - - - - - - - - Phage_Mu_F,Phage_portal k59_421694_1 399795.CtesDRAFT_PD0612 2.6e-05 52.4 COG3209@1|root,COG3210@1|root,COG4675@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,COG4675@2|Bacteria,1RJRG@1224|Proteobacteria,2WEZQ@28216|Betaproteobacteria 28216|Betaproteobacteria M COG3209 Rhs family protein - - - - - - - - - - - - - k59_135413_1 553171.HMPREF0648_0995 1.1e-17 78.6 COG1943@1|root,COG1943@2|Bacteria,4NWI3@976|Bacteroidetes,2FZ9S@200643|Bacteroidia 976|Bacteroidetes L Transposase IS200 like - - - ko:K07491 - - - - ko00000 - - - Y1_Tnp k59_527699_1 1089549.AZUQ01000001_gene1354 4.72e-06 56.2 COG5519@1|root,COG5519@2|Bacteria,2I395@201174|Actinobacteria,4F07U@85014|Glycomycetales 201174|Actinobacteria L Bifunctional DNA primase/polymerase, N-terminal - - - - - - - - - - - - Prim-Pol k59_651564_1 1410620.SHLA_101c000120 9.71e-10 65.9 COG0714@1|root,COG0714@2|Bacteria,1PQFK@1224|Proteobacteria,2V2UH@28211|Alphaproteobacteria,4BJN1@82115|Rhizobiaceae 28211|Alphaproteobacteria O AAA domain (dynein-related subfamily) - - - - - - - - - - - - AAA_5 k59_503343_1 1618237.A0A0C5IMG6_9CIRC 1.42e-17 85.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_487265_1 1226994.AMZB01000059_gene3617 1.99e-11 72.0 COG3096@1|root,COG5281@1|root,COG5283@1|root,COG3096@2|Bacteria,COG5281@2|Bacteria,COG5283@2|Bacteria,1MX2R@1224|Proteobacteria,1S3MM@1236|Gammaproteobacteria,1YGRX@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria D tape measure protein Z012_10445 - - - - - - - - - - - Phage_HK97_TLTM,Tape_meas_lam_C k59_358181_1 67356.KL575597_gene7661 0.000331 45.4 COG0726@1|root,COG4409@1|root,COG0726@2|Bacteria,COG4409@2|Bacteria,2IC87@201174|Actinobacteria 201174|Actinobacteria G Polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 k59_195936_1 1444310.JANV01000096_gene3265 0.000267 48.9 COG0526@1|root,COG0526@2|Bacteria 2|Bacteria CO cell redox homeostasis - - - - - - - - - - - - DUF4369,Omp28 k59_277561_1 1123320.KB889672_gene3707 1.44e-48 185.0 COG0392@1|root,COG0392@2|Bacteria,2GMAV@201174|Actinobacteria 201174|Actinobacteria T integral membrane protein - - - - - - - - - - - - LPG_synthase_TM k59_277561_2 1519464.HY22_05510 0.0001 45.1 COG0671@1|root,COG0671@2|Bacteria,1FFPS@1090|Chlorobi 1090|Chlorobi I PAP2 superfamily - - - - - - - - - - - - PAP2 k59_214023_1 1618248.A0A0C5IB82_9CIRC 5.82e-84 260.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_346590_1 1540095.A0A0A0YTT7_9CAUD 0.000137 48.9 4QAK6@10239|Viruses,4QPBY@28883|Caudovirales,4QI82@10662|Myoviridae 10662|Myoviridae S virus tail, fiber - GO:0005575,GO:0019012 - - - - - - - - - - - k59_655790_2 1788454.A0A190WHE4_9CIRC 2.97e-57 192.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_588521_2 1121924.ATWH01000001_gene4299 8.62e-18 92.4 COG3291@1|root,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria,4FKX3@85023|Microbacteriaceae 201174|Actinobacteria G Repeats in polycystic kidney disease 1 (PKD1) and other proteins wcoG - - - - - - - - - - - Laminin_G_3,PKD k59_449021_1 390989.JOEG01000021_gene2617 3.51e-56 192.0 COG1572@1|root,COG1572@2|Bacteria,2GJ8Y@201174|Actinobacteria,4DCGB@85008|Micromonosporales 201174|Actinobacteria S Glycosyl hydrolase family 71 - - - - - - - - - - - - Glyco_hydro_71 k59_403598_2 942016.E9NID5_9CAUD 2.01e-07 51.6 4QBMV@10239|Viruses,4QUU6@35237|dsDNA viruses no RNA stage,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_113481_1 411470.RUMGNA_01746 0.000992 45.4 COG2137@1|root,COG2137@2|Bacteria,1V72V@1239|Firmicutes,24J7X@186801|Clostridia,3Y0I4@572511|Blautia 186801|Clostridia S Regulatory protein RecX recX - - ko:K03565 - - - - ko00000,ko03400 - - - RecX k59_15426_2 1235802.C823_01510 1.76e-14 74.7 COG4626@1|root,COG4626@2|Bacteria,1TPU1@1239|Firmicutes,248RI@186801|Clostridia,25W4U@186806|Eubacteriaceae 186801|Clostridia S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_261481_2 521674.Plim_0014 2.96e-78 246.0 COG1351@1|root,COG1351@2|Bacteria 2|Bacteria F thymidylate synthase (FAD) activity thyX - 2.1.1.148 ko:K03465 ko00240,ko00670,ko01100,map00240,map00670,map01100 - R06613 RC00022,RC00332 ko00000,ko00001,ko01000 - - - Thy1 k59_52686_1 1436889.W6ASK4_9CAUD 2.84e-08 60.1 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales 28883|Caudovirales S N-acetylmuramoyl-L-alanine amidase activity - - - - - - - - - - - - - k59_157530_1 908340.HMPREF9406_2595 5.68e-39 145.0 COG0553@1|root,COG0553@2|Bacteria,1TP2C@1239|Firmicutes,24DVA@186801|Clostridia,36FNM@31979|Clostridiaceae 186801|Clostridia L SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,N6_N4_Mtase,SNF2_N k59_241663_2 755731.Clo1100_2169 5.06e-34 129.0 2CWXD@1|root,32T0J@2|Bacteria,1VCVP@1239|Firmicutes,24MPK@186801|Clostridia,36KI7@31979|Clostridiaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_159926_1 948071.S4S2S9_9CAUD 9.27e-43 164.0 4QBYN@10239|Viruses,4QZT8@35237|dsDNA viruses no RNA stage,4QR5G@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_387632_1 1035308.AQYY01000002_gene859 2.73e-09 63.5 COG1409@1|root,COG4932@1|root,COG1409@2|Bacteria,COG4932@2|Bacteria,1UNMY@1239|Firmicutes,25H2U@186801|Clostridia,267I4@186807|Peptococcaceae 2|Bacteria M domain protein - - - ko:K20276 ko02024,map02024 - - - ko00000,ko00001 - - - Big_3_2,Big_3_3,CHU_C,Metallophos k59_18582_1 1234888.K0A2J2_9VIRU 4.95e-13 69.7 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_633498_1 1234888.K0A2J2_9VIRU 4.89e-54 187.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_38528_4 242861.Q6UYH1_9CAUD 1.96e-14 72.0 4QB07@10239|Viruses,4QUZW@35237|dsDNA viruses no RNA stage,4QPGS@28883|Caudovirales,4QMBY@10699|Siphoviridae 10699|Siphoviridae S Domain of unknown function (DUF4326) - - - - - - - - - - - - - k59_634472_2 1288494.EBAPG3_9520 3.05e-05 48.5 COG0582@1|root,COG0582@2|Bacteria,1N2H9@1224|Proteobacteria,2VT4R@28216|Betaproteobacteria,3723T@32003|Nitrosomonadales 28216|Betaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_3,Phage_integrase k59_325632_1 634176.NT05HA_0494 9.74e-56 190.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,1TKGR@1236|Gammaproteobacteria,1Y7SY@135625|Pasteurellales 135625|Pasteurellales S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_203059_1 316057.RPD_1986 1.36e-09 64.7 COG5281@1|root,COG5281@2|Bacteria,1R47M@1224|Proteobacteria,2TUIV@28211|Alphaproteobacteria,3JY6I@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S COG5281, Phage-related minor tail protein - - - - - - - - - - - - - k59_56377_1 1414739.W6AT00_9CAUD 3.04e-05 55.5 4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - GO:0008150,GO:0044403,GO:0044409,GO:0044411,GO:0044419,GO:0051701,GO:0051704,GO:0051828,GO:0051830,GO:0085027 - - - - - - - - - - - k59_305518_2 751945.Theos_1690 4.06e-56 187.0 2CHRY@1|root,30Z9E@2|Bacteria,1WN8T@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus - - - - - - - - - - - - - - - k59_81562_2 864069.MicloDRAFT_00037670 4.37e-105 335.0 COG1061@1|root,COG1061@2|Bacteria,1N52C@1224|Proteobacteria,2U3TE@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Type III restriction enzyme, res subunit - - - - - - - - - - - - Helicase_C,ResIII k59_40776_1 691965.D4P7I3_9CAUD 1.8e-93 305.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_40776_3 428125.CLOLEP_01377 1.44e-41 144.0 2E0G5@1|root,32W28@2|Bacteria,1VAS0@1239|Firmicutes,24NYA@186801|Clostridia,3WNKT@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_511963_2 886882.PPSC2_p0514 8.36e-31 119.0 2EN4Y@1|root,30UJG@2|Bacteria,1U1MI@1239|Firmicutes,4IB3Y@91061|Bacilli,273NQ@186822|Paenibacillaceae 91061|Bacilli - - - - - - - - - - - - - - - k59_244647_2 1236000.L0AQZ2_9CAUD 1.24e-38 134.0 4QEGD@10239|Viruses,4QVU1@35237|dsDNA viruses no RNA stage,4QPN9@28883|Caudovirales,4QJCM@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_244647_3 1264700.L0MYI2_9CAUD 2.35e-154 458.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QI9F@10662|Myoviridae 10662|Myoviridae S Type III restriction enzyme, res subunit - - - - - - - - - - - - - k59_511974_1 673376.F2VHW3_9CAUD 1.6e-31 119.0 4QBHW@10239|Viruses,4QW8N@35237|dsDNA viruses no RNA stage,4QTT7@28883|Caudovirales,4QKR7@10699|Siphoviridae 10699|Siphoviridae S sequence-specific DNA binding transcription factor activity - - - - - - - - - - - - - k59_327641_1 1278073.MYSTI_03261 1.96e-05 52.0 COG3740@1|root,COG3740@2|Bacteria,1NBQ9@1224|Proteobacteria,431K2@68525|delta/epsilon subdivisions,2WX1Z@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Caudovirus prohead serine protease - - - - - - - - - - - - Peptidase_S78 k59_594420_1 1556290.A0A0A0RQI3_9CAUD 8.08e-77 259.0 4QCZC@10239|Viruses,4QRH3@28883|Caudovirales,4QM07@10699|Siphoviridae 10699|Siphoviridae S Bacterial DNA polymerase III alpha subunit - - - - - - - - - - - - - k59_81615_2 742733.HMPREF9469_05037 1.23e-24 97.1 2BD7A@1|root,326VE@2|Bacteria,1USRB@1239|Firmicutes,25ASG@186801|Clostridia,223BG@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_224212_1 479434.Sthe_1218 8.44e-23 105.0 COG0728@1|root,COG0728@2|Bacteria,2G5MD@200795|Chloroflexi,27XGY@189775|Thermomicrobia 189775|Thermomicrobia S Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane - - - ko:K03980 - - - - ko00000,ko01011,ko02000 2.A.66.4 - - MVIN k59_60138_1 365044.Pnap_1638 5.95e-09 63.5 COG4932@1|root,COG4932@2|Bacteria 2|Bacteria M domain protein - - - - - - - - - - - - CHU_C,Calx-beta,Collagen_bind,DUF11,Gram_pos_anchor,SdrD_B k59_368449_2 105154.Q9MBU3_9VIRU 1.06e-08 60.5 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_368449_3 105154.Q9MBU6_9VIRU 8.6e-64 212.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_121788_2 268739.Nmlp_1149 2.8e-10 68.9 COG0419@1|root,arCOG00368@2157|Archaea,2XX1N@28890|Euryarchaeota,23VV7@183963|Halobacteria 183963|Halobacteria L Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex - - - - - - - - - - - - Peptidase_S74 k59_224318_1 679201.HMPREF9334_00311 2.38e-66 224.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4H2W4@909932|Negativicutes 909932|Negativicutes L SNF2 family - - - - - - - - - - - - Helicase_C,SNF2_N k59_368469_1 105154.Q9MBU6_9VIRU 1.35e-33 128.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_368469_4 105154.Q9MBU0_9VIRU 3.4e-69 224.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_60198_1 1609634.A0A0C5AFV4_9VIRU 1.78e-73 241.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_368525_2 1788445.A0A190WHA3_9CIRC 2.62e-43 156.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_121897_1 1219035.NT2_05_03750 1.06e-09 59.3 COG3772@1|root,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,2U7X4@28211|Alphaproteobacteria,2K9AH@204457|Sphingomonadales 204457|Sphingomonadales G lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_121897_2 1480731.X2KUH8_9CAUD 4.75e-08 65.5 4QAK6@10239|Viruses,4QPBY@28883|Caudovirales 28883|Caudovirales S N-acetylmuramoyl-L-alanine amidase activity - GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0008150,GO:0016032,GO:0016787,GO:0016798,GO:0019012,GO:0019058,GO:0019062,GO:0022610,GO:0044403,GO:0044406,GO:0044409,GO:0044411,GO:0044419,GO:0044423,GO:0044650,GO:0051701,GO:0051704,GO:0051828,GO:0051830,GO:0085027,GO:0098015,GO:0098024 - - - - - - - - - - - k59_121901_1 1005395.CSV86_06226 1.87e-20 93.6 COG3206@1|root,COG3206@2|Bacteria,1ND5H@1224|Proteobacteria,1RNXC@1236|Gammaproteobacteria 1236|Gammaproteobacteria M DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease - - - - - - - - - - - - Rad52_Rad22 k59_60227_1 1048339.KB913029_gene3575 1.03e-62 202.0 COG1351@1|root,COG1351@2|Bacteria,2HCNJ@201174|Actinobacteria 201174|Actinobacteria F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant thyX GO:0000166,GO:0003674,GO:0003824,GO:0004799,GO:0005488,GO:0008150,GO:0008152,GO:0008168,GO:0016740,GO:0016741,GO:0032259,GO:0036094,GO:0040007,GO:0042083,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050797,GO:0070402,GO:0097159,GO:1901265,GO:1901363 2.1.1.148 ko:K03465 ko00240,ko00670,ko01100,map00240,map00670,map01100 - R06613 RC00022,RC00332 ko00000,ko00001,ko01000 - - iNJ661.Rv2754c Thy1 k59_60227_2 767434.Fraau_1461 2.51e-05 47.8 COG1694@1|root,COG1694@2|Bacteria,1N3XF@1224|Proteobacteria,1SSUP@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Mazg nucleotide pyrophosphohydrolase - - - - - - - - - - - - - k59_368634_1 666685.R2APBS1_2704 0.00082 49.7 COG3209@1|root,COG4733@1|root,COG3209@2|Bacteria,COG4733@2|Bacteria,1MVV1@1224|Proteobacteria,1RP75@1236|Gammaproteobacteria,1X54E@135614|Xanthomonadales 135614|Xanthomonadales M rhs family - - - - - - - - - - - - RHS_repeat k59_368692_3 411470.RUMGNA_00207 3.59e-19 85.9 29CPM@1|root,2ZZMW@2|Bacteria,1V5MJ@1239|Firmicutes,25HQ9@186801|Clostridia 186801|Clostridia S VRR_NUC - - - - - - - - - - - - VRR_NUC k59_368698_1 1563661.A0A097PAJ0_9CAUD 0.000314 46.6 4QBMV@10239|Viruses,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_368731_1 1051632.TPY_2737 2.75e-32 129.0 COG0863@1|root,COG0863@2|Bacteria,1TR56@1239|Firmicutes,248NR@186801|Clostridia,3WCTG@538999|Clostridiales incertae sedis 186801|Clostridia L DNA methylase cfr9IM - 2.1.1.113 ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_224525_10 1121445.ATUZ01000003_gene36 4.95e-08 62.4 COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,42QA8@68525|delta/epsilon subdivisions,2WJBW@28221|Deltaproteobacteria,2M8NS@213115|Desulfovibrionales 28221|Deltaproteobacteria S PFAM ATPase associated with various cellular activities - - - - - - - - - - - - AAA_3,AAA_5 k59_246220_1 691965.D4P7C5_9CAUD 0.0 919.0 4QBV3@10239|Viruses,4QW0W@35237|dsDNA viruses no RNA stage,4QPPJ@28883|Caudovirales,4QKW5@10699|Siphoviridae 10699|Siphoviridae S Phage Terminase - - - - - - - - - - - - - k59_533364_7 1168289.AJKI01000011_gene567 1.15e-14 82.0 COG5295@1|root,COG5295@2|Bacteria,4NV9S@976|Bacteroidetes,2FYT9@200643|Bacteroidia 976|Bacteroidetes UW serine threonine protein kinase - - - - - - - - - - - - DUF1566 k59_328250_1 467661.RKLH11_3555 2.96e-07 60.5 28JTG@1|root,2Z7PY@2|Bacteria,1QVNY@1224|Proteobacteria 1224|Proteobacteria S Protein of unknown function (DUF2793) - - - - - - - - - - - - DUF2793 k59_421083_1 520999.PROVALCAL_00771 2.38e-22 95.1 COG3409@1|root,COG3409@2|Bacteria,1R4RS@1224|Proteobacteria,1S346@1236|Gammaproteobacteria 1236|Gammaproteobacteria M CHAP domain - - - - - - - - - - - - CHAP k59_153807_1 186617.M9M8L2_9VIRU 1.53e-56 195.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_341888_2 305700.B447_04933 1.13e-17 79.7 2EBGC@1|root,335GX@2|Bacteria,1NC6Y@1224|Proteobacteria,2VWRZ@28216|Betaproteobacteria,2KZHU@206389|Rhodocyclales 206389|Rhodocyclales - - - - - - - - - - - - - - - k59_564155_1 1283076.M1HM36_9CAUD 4.52e-33 124.0 4QCXM@10239|Viruses,4QZZ5@35237|dsDNA viruses no RNA stage,4QT8U@28883|Caudovirales,4QJ27@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_317213_2 10506.Q98540_PBCV1 2.3e-13 74.7 4QC9Q@10239|Viruses,4R0EV@35237|dsDNA viruses no RNA stage 10239|Viruses - - - - - - - - - - - - - - - k59_444806_1 443143.GM18_2891 1.68e-08 57.0 COG4227@1|root,COG4227@2|Bacteria,1MU8I@1224|Proteobacteria,42N43@68525|delta/epsilon subdivisions,2WM7N@28221|Deltaproteobacteria 28221|Deltaproteobacteria L Domain of unknown function (DUF1738) - - - - - - - - - - - - DUF1738,Toprim_3 k59_380643_2 1129146.H2BDB2_9CAUD 1.1e-38 138.0 4QEAQ@10239|Viruses,4QVWS@35237|dsDNA viruses no RNA stage,4QQWE@28883|Caudovirales,4QMGH@10699|Siphoviridae 10699|Siphoviridae S transferase activity, transferring glycosyl groups - - - - - - - - - - - - - k59_380643_5 314230.DSM3645_28572 1.2e-14 80.5 COG0457@1|root,COG1216@1|root,COG0457@2|Bacteria,COG1216@2|Bacteria,2J1FB@203682|Planctomycetes 203682|Planctomycetes S Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 k59_213936_1 1234888.K0A2J2_9VIRU 2.43e-48 172.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_72583_1 1540097.A0A0A0YU59_9CAUD 1.24e-32 128.0 4QB3X@10239|Viruses,4QPEE@28883|Caudovirales,4QNCI@10744|Podoviridae 10744|Podoviridae S VWA-like domain (DUF2201) - - - - - - - - - - - - - k59_400569_1 2003327.CAPSD_BPCHP 5.97e-37 142.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_31473_2 553217.ENHAE0001_2201 1.18e-31 115.0 2EE3H@1|root,337Y3@2|Bacteria,1NF3P@1224|Proteobacteria,1SJGT@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_323816_2 517418.Ctha_1820 7.18e-05 48.9 COG1073@1|root,COG1073@2|Bacteria 2|Bacteria S thiolester hydrolase activity mhpC - - ko:K06889 - - - - ko00000 - - - Hydrolase_4 k59_362644_3 563192.HMPREF0179_05148 4.48e-40 140.0 COG1092@1|root,COG1092@2|Bacteria,1RDWK@1224|Proteobacteria,42ZM3@68525|delta/epsilon subdivisions,2WUW8@28221|Deltaproteobacteria,2MBQK@213115|Desulfovibrionales 28221|Deltaproteobacteria J Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA - - - - - - - - - - - - - k59_37056_1 370438.PTH_2512 2.29e-45 152.0 COG1943@1|root,COG1943@2|Bacteria,1V1CM@1239|Firmicutes,24BK2@186801|Clostridia,262Y3@186807|Peptococcaceae 186801|Clostridia L PFAM Transposase IS200 like - - - ko:K07491 - - - - ko00000 - - - Y1_Tnp k59_282794_1 691965.D4P7L7_9CAUD 1.92e-90 293.0 4QB9J@10239|Viruses,4QXFE@35237|dsDNA viruses no RNA stage,4QS1Z@28883|Caudovirales,4QN8F@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_633005_1 1609634.A0A0C5ANA6_9VIRU 2.65e-15 79.0 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_218700_1 1618256.A0A0C5IM93_9CIRC 1.17e-34 134.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_55009_1 1073754.G0ZNE5_9VIRU 4.74e-20 89.7 4QAIU@10239|Viruses 10239|Viruses S HNH endonuclease - - - - - - - - - - - - - k59_183050_1 1150469.RSPPHO_02396 3.63e-33 126.0 COG1793@1|root,COG1793@2|Bacteria 2|Bacteria L dna ligase lig GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 ko:K10747 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00381,R00382,R10822,R10823 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - DNA_ligase_A_M,DNA_ligase_OB_2 k59_183050_3 598659.NAMH_0358 8.25e-38 132.0 COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,42SJS@68525|delta/epsilon subdivisions,2YRU7@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA dut - 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - iIT341.HP0865 dUTPase k59_183050_13 1498011.A0A096XUV4_9CAUD 1.03e-22 95.5 4QBHW@10239|Viruses,4QTT7@28883|Caudovirales,4QNKM@10744|Podoviridae 10744|Podoviridae S transferase activity, transferring alkyl or aryl (other than methyl) groups - - - - - - - - - - - - - k59_183050_14 1094755.MCO_00096 6.32e-06 48.5 COG2452@1|root,COG2452@2|Bacteria,1QV30@1224|Proteobacteria,2V4ZN@28211|Alphaproteobacteria,48TYJ@772|Bartonellaceae 28211|Alphaproteobacteria L Resolvase, N terminal domain - - - - - - - - - - - - MerR,Resolvase k59_387043_1 1329516.JPST01000014_gene652 1.2e-05 46.6 COG1694@1|root,COG1694@2|Bacteria,1VIQA@1239|Firmicutes,4HM6C@91061|Bacilli 91061|Bacilli S Nucleotide pyrophosphohydrolase - - - - - - - - - - - - MazG k59_55931_2 69328.PVLB_20830 2.04e-24 109.0 COG4695@1|root,COG4695@2|Bacteria,1MUP5@1224|Proteobacteria,1RPB0@1236|Gammaproteobacteria 1236|Gammaproteobacteria S portal protein - - - - - - - - - - - - Phage_portal k59_265532_2 1538804.A0A088F6T3_9CAUD 1.15e-66 228.0 4QAKM@10239|Viruses,4QPEF@28883|Caudovirales,4QKNE@10699|Siphoviridae 10699|Siphoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_79358_2 862908.BMS_1457 1.86e-18 82.0 COG1694@1|root,COG1694@2|Bacteria 2|Bacteria FG Mazg nucleotide pyrophosphohydrolase MA20_27270 - - - - - - - - - - - MazG k59_634011_1 1122201.AUAZ01000017_gene2960 9.66e-58 209.0 COG5362@1|root,COG5362@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Terminase_6C k59_363649_1 27923.ML013510a-PA 3.65e-08 60.1 COG0367@1|root,KOG0571@2759|Eukaryota,38H99@33154|Opisthokonta,3BECT@33208|Metazoa 33208|Metazoa E L-asparagine biosynthetic process - - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 k59_305123_3 1038860.AXAP01000015_gene2006 1.64e-09 61.6 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,2U6BJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S TIGRFAM phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_473098_2 745014.OMB55_00019200 2.65e-34 127.0 COG0582@1|root,COG0582@2|Bacteria 2|Bacteria L DNA integration - - - - - - - - - - - - Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase k59_83345_1 1005995.GTPT_2564 7.38e-09 58.9 COG2932@1|root,COG2932@2|Bacteria,1N4SP@1224|Proteobacteria,1SYN0@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Peptidase S24-like - - - - - - - - - - - - HTH_3,Peptidase_S24,Phage_CI_repr k59_616903_3 449673.BACSTE_02196 1.54e-54 189.0 COG1475@1|root,COG1475@2|Bacteria,4P1X3@976|Bacteroidetes,2FQKQ@200643|Bacteroidia,4AQK8@815|Bacteroidaceae 976|Bacteroidetes K ParB-like nuclease domain - - - - - - - - - - - - DUF4417,ParBc k59_473500_2 469660.A8HNX4_9CAUD 8.42e-26 104.0 4QBFN@10239|Viruses,4QXWN@35237|dsDNA viruses no RNA stage,4QPTW@28883|Caudovirales,4QNPZ@10744|Podoviridae 10744|Podoviridae S Phage stabilisation protein - - - - - - - - - - - - - k59_452832_4 314271.RB2654_05280 4.72e-14 76.3 COG5281@1|root,COG5281@2|Bacteria,1R47M@1224|Proteobacteria,2TUIV@28211|Alphaproteobacteria 28211|Alphaproteobacteria S COG5281, Phage-related minor tail protein - - - - - - - - - - - - - k59_205904_1 1007105.PT7_P068 1.46e-63 206.0 2DXNB@1|root,345PI@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_62927_1 156889.Mmc1_2604 4.45e-103 312.0 COG1475@1|root,COG4725@1|root,COG1475@2|Bacteria,COG4725@2|Bacteria,1R553@1224|Proteobacteria,2TRP6@28211|Alphaproteobacteria 28211|Alphaproteobacteria KT Belongs to the MT-A70-like family - - - - - - - - - - - - MT-A70 k59_62927_2 571166.KI421509_gene3812 2.65e-29 112.0 28PMA@1|root,2ZCAD@2|Bacteria,1RARQ@1224|Proteobacteria,2U6X3@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_83744_2 1788449.A0A190WHL0_9CIRC 4.94e-28 113.0 4QBFZ@10239|Viruses,4QUKU@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_514539_1 996637.SGM_4307 4.16e-09 65.5 COG0739@1|root,COG0739@2|Bacteria,2GU2Q@201174|Actinobacteria 201174|Actinobacteria M peptidase - - - - - - - - - - - - Peptidase_M23 k59_575823_1 536232.CLM_2512 1.36e-28 121.0 COG5283@1|root,COG5293@1|root,COG5283@2|Bacteria,COG5293@2|Bacteria,1UHQM@1239|Firmicutes,25E9Q@186801|Clostridia,36USH@31979|Clostridiaceae 186801|Clostridia D phage tail tape measure protein - - - - - - - - - - - - PhageMin_Tail k59_493691_1 74545.EU96_0210 1.09e-29 122.0 COG1061@1|root,COG4889@1|root,COG1061@2|Bacteria,COG4889@2|Bacteria,1G4WD@1117|Cyanobacteria,1MNED@1212|Prochloraceae 1117|Cyanobacteria L Helicase associated domain - - - - - - - - - - - - HA,Helicase_C,Mrr_cat_2,ResIII k59_247960_2 693272.E3T5B8_CROVB 6.75e-19 83.2 4QAXN@10239|Viruses,4QVNW@35237|dsDNA viruses no RNA stage 10239|Viruses S D12 class N6 adenine-specific DNA methyltransferase - - - - - - - - - - - - - k59_391234_1 186617.M9M8L2_9VIRU 2.47e-30 122.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_66996_1 1327983.R9ZYX6_9CAUD 5.95e-11 61.6 4QAIJ@10239|Viruses,4QVZ9@35237|dsDNA viruses no RNA stage,4QPXI@28883|Caudovirales,4QNHT@10744|Podoviridae 10744|Podoviridae S C-5 cytosine-specific DNA methylase - - - - - - - - - - - - - k59_251959_1 269482.Bcep1808_1155 1.3e-30 116.0 2DM17@1|root,319VU@2|Bacteria,1R6RI@1224|Proteobacteria,2WG8E@28216|Betaproteobacteria,1KIBI@119060|Burkholderiaceae 28216|Betaproteobacteria L PFAM GIY-YIG catalytic domain - - - - - - - - - - - - - k59_312285_4 1122599.AUGR01000001_gene288 1.25e-50 169.0 COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,1SQ0T@1236|Gammaproteobacteria 1236|Gammaproteobacteria L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_45523_1 417280.A1YZY4_9CAUD 7.78e-108 337.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QI9F@10662|Myoviridae 10662|Myoviridae S Type III restriction enzyme, res subunit - - - - - - - - - - - - - k59_251974_2 5217.XP_007004332.1 2.66e-20 91.7 COG1087@1|root,KOG1371@2759|Eukaryota,38C46@33154|Opisthokonta,3NVGX@4751|Fungi,3UYJA@5204|Basidiomycota,3VETN@5234|Tremellales 4751|Fungi M Galactose metabolism-related protein GAL10 GO:0003674,GO:0003824,GO:0003978,GO:0004034,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006012,GO:0006464,GO:0006486,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019318,GO:0019320,GO:0019388,GO:0019538,GO:0033499,GO:0034645,GO:0036211,GO:0042125,GO:0042802,GO:0042803,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046983,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.1.3.2,5.1.3.3 ko:K01784,ko:K01785 ko00010,ko00052,ko00520,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map00520,map01100,map01110,map01120,map01130 M00361,M00362,M00632 R00291,R01602,R02984,R10619 RC00289,RC00563 ko00000,ko00001,ko00002,ko01000 - - iMM904.YBR019C,iND750.YBR019C Aldose_epim,Epimerase,GDP_Man_Dehyd k59_437575_1 471854.Dfer_1756 1.19e-38 152.0 COG1749@1|root,COG3386@1|root,COG1749@2|Bacteria,COG3386@2|Bacteria,4NTUT@976|Bacteroidetes 976|Bacteroidetes N Domain of unknown function (DUF4082) - - - - - - - - - - - - Cu-binding_MopE,DUF4082 k59_88482_1 997346.HMPREF9374_0456 1.01e-16 83.2 COG0302@1|root,COG0302@2|Bacteria,1TRNM@1239|Firmicutes,4HAXS@91061|Bacilli,27B0B@186824|Thermoactinomycetaceae 91061|Bacilli H GTP cyclohydrolase I folE GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydroI k59_67499_2 462590.A9J528_BPPYU 1.25e-07 50.8 4QE7X@10239|Viruses,4QVF0@35237|dsDNA viruses no RNA stage,4QPUM@28883|Caudovirales,4QMAZ@10699|Siphoviridae 10699|Siphoviridae S Cytidine and deoxycytidylate deaminase zinc-binding region - - - - - - - - - - - - - k59_643667_2 1121101.HMPREF1532_04034 2.51e-30 117.0 COG3023@1|root,COG3023@2|Bacteria,4P4CH@976|Bacteroidetes,2FRT5@200643|Bacteroidia,4AQU8@815|Bacteroidaceae 976|Bacteroidetes V N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - Amidase_2 k59_579886_1 575540.Isop_2441 1.41e-17 80.5 2CEI6@1|root,2ZED5@2|Bacteria,2J3S1@203682|Planctomycetes 203682|Planctomycetes S Protein of unknown function (DUF669) - - - - - - - - - - - - DUF669 k59_335458_1 469383.Cwoe_4526 5.56e-40 160.0 COG1061@1|root,COG1061@2|Bacteria,2GIU5@201174|Actinobacteria,4CPQY@84995|Rubrobacteria 84995|Rubrobacteria L type III restriction enzyme, res subunit - - - - - - - - - - - - Helicase_C,ResIII k59_129277_1 110365.A0A023AXA1 4.57e-23 103.0 2EWQP@1|root,2SYH6@2759|Eukaryota 2759|Eukaryota S RNA helicase - - - - - - - - - - - - RNA_helicase,Viral_Rep k59_600573_1 592028.GCWU000321_01367 3.42e-24 105.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4H2W4@909932|Negativicutes 909932|Negativicutes L SNF2 family - - - - - - - - - - - - Helicase_C,SNF2_N k59_316345_3 388051.AUFE01000035_gene4020 5.68e-46 163.0 COG4653@1|root,COG4653@2|Bacteria 2|Bacteria G Phage capsid family - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_526367_2 1313172.YM304_09440 4.06e-34 140.0 COG1061@1|root,COG1061@2|Bacteria,2GIU5@201174|Actinobacteria 201174|Actinobacteria L type III restriction enzyme, res subunit sdrA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - ResIII k59_71845_2 1530186.JQEY01000010_gene2771 2.48e-69 215.0 2EKAM@1|root,33E0W@2|Bacteria,1MYSP@1224|Proteobacteria,2UBGW@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_650257_2 929712.KI912613_gene4074 9.18e-19 85.5 2EGA5@1|root,33A1Y@2|Bacteria,2GSDD@201174|Actinobacteria 201174|Actinobacteria S HNH endonuclease - - - - - - - - - - - - HNH_3 k59_650257_4 1244531.CIG1485E_1177 1.28e-10 63.5 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,42RN6@68525|delta/epsilon subdivisions,2YP9W@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_650257_5 1410634.JHVD01000028_gene2099 2.32e-10 62.0 COG4570@1|root,COG4570@2|Bacteria,2GV9V@201174|Actinobacteria 201174|Actinobacteria L Endodeoxyribonuclease RusA - - - - - - - - - - - - RusA k59_546721_1 1090320.KB900605_gene3208 1.83e-06 57.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2TSDW@28211|Alphaproteobacteria,2K42P@204457|Sphingomonadales 204457|Sphingomonadales S Terminase - - - - - - - - - - - - Terminase_1 k59_195076_2 1340810.V5UTB4_9CAUD 1.05e-06 60.8 4QB3T@10239|Viruses,4QWCJ@35237|dsDNA viruses no RNA stage,4QS7B@28883|Caudovirales,4QK0J@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_49693_1 596153.Alide_1431 1.17e-66 221.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2VNHP@28216|Betaproteobacteria,4AC68@80864|Comamonadaceae 28216|Betaproteobacteria S Terminase - - - - - - - - - - - - Terminase_1 k59_526471_1 411460.RUMTOR_01350 1.93e-08 56.2 2EAAT@1|root,334F2@2|Bacteria,1VJJI@1239|Firmicutes,24TQU@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_347812_1 1618248.A0A0C5IB82_9CIRC 1.45e-22 98.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_610184_1 1430440.MGMSRv2_2300 1.11e-26 113.0 COG4733@1|root,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria,2TV2W@28211|Alphaproteobacteria,2JV2T@204441|Rhodospirillales 204441|Rhodospirillales S COG4733 Phage-related protein, tail component - - - - - - - - - - - - Lambda_tail_I,Phage-tail_3 k59_217357_3 861454.HMPREF9099_02237 5.93e-05 45.8 COG2189@1|root,COG2189@2|Bacteria 2|Bacteria L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.72 ko:K00571,ko:K07316 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_507229_1 622312.ROSEINA2194_03627 2.07e-30 119.0 28MKK@1|root,2ZAWR@2|Bacteria,1UYAT@1239|Firmicutes,24GI2@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - RNA_helicase,Viral_Rep k59_114606_1 1327990.S0A3B9_9CAUD 1.15e-13 67.8 4QC5A@10239|Viruses,4QX98@35237|dsDNA viruses no RNA stage,4QRV3@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_426086_1 1026955.F5B3N1_9CAUD 8.32e-31 122.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales 28883|Caudovirales S N-acetylmuramoyl-L-alanine amidase activity - GO:0005575,GO:0019012,GO:0019028,GO:0019030,GO:0039617,GO:0044423,GO:0046729 - - - - - - - - - - - k59_200128_3 313594.PI23P_11187 2.6e-53 178.0 2DB9A@1|root,2Z7VI@2|Bacteria,4NJ4U@976|Bacteroidetes,1HXKW@117743|Flavobacteriia 976|Bacteroidetes S Adenine-specific methyltransferase EcoRI - - - - - - - - - - - - EcoRI_methylase k59_102200_2 1538804.A0A088F6Q5_9CAUD 7.94e-19 86.3 4QFED@10239|Viruses,4QPEH@28883|Caudovirales,4QN2V@10699|Siphoviridae 10699|Siphoviridae S tRNA modification - - - - - - - - - - - - - k59_240651_1 5786.XP_003294292.1 2.1e-28 116.0 COG1372@1|root,2QRRC@2759|Eukaryota,3XA2K@554915|Amoebozoa 554915|Amoebozoa F reductase - GO:0003674,GO:0003824,GO:0004748,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009141,GO:0009142,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_386341_1 1788443.A0A190WHB4_9CIRC 4.49e-12 66.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_282212_2 1121007.AUML01000009_gene3782 5.27e-51 163.0 29D93@1|root,30071@2|Bacteria,4PH46@976|Bacteroidetes,1IHUK@117743|Flavobacteriia,2YJQX@290174|Aquimarina 976|Bacteroidetes - - - - - - - - - - - - - - - k59_246218_2 1609634.A0A0C5AFV4_9VIRU 2.14e-78 262.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_41132_1 1230343.CANP01000008_gene882 1.48e-13 75.5 COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,1RPZ7@1236|Gammaproteobacteria,1JC8A@118969|Legionellales 118969|Legionellales L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA - - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII k59_533535_10 742733.HMPREF9469_05026 7.8e-83 253.0 28NM4@1|root,2ZBMQ@2|Bacteria,1V1QD@1239|Firmicutes,24G1B@186801|Clostridia,221N8@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_533535_11 428125.CLOLEP_01417 1.09e-52 173.0 2CGG9@1|root,2ZVSJ@2|Bacteria,1V633@1239|Firmicutes,24HD0@186801|Clostridia,3WMXK@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_533535_14 1537917.JU82_09980 1.22e-33 120.0 2ARVA@1|root,31H70@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - HK97-gp10_like k59_533535_15 742733.HMPREF9469_05020 2.29e-133 469.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia,221IX@1506553|Lachnoclostridium 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_533535_23 478749.BRYFOR_08569 1.05e-31 125.0 2A0KC@1|root,30NQJ@2|Bacteria,1V3K4@1239|Firmicutes,24HYK@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_307885_1 1385658.U5KPZ6_9VIRU 4.47e-125 376.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_82487_1 1068978.AMETH_6319 1.39e-10 68.6 COG3409@1|root,COG3409@2|Bacteria,2GRFR@201174|Actinobacteria,4EE9A@85010|Pseudonocardiales 201174|Actinobacteria M Putative peptidoglycan binding domain - - - - - - - - - - - - PG_binding_1 k59_82487_8 742735.HMPREF9467_00071 3.01e-07 62.0 COG3266@1|root,COG3266@2|Bacteria,1UIAK@1239|Firmicutes,25EFR@186801|Clostridia,223R6@1506553|Lachnoclostridium 186801|Clostridia M to Mitochondrial intermediate peptidase K01410 - - - - - - - - - - - - Collagen k59_82487_9 742740.HMPREF9474_02274 2.09e-31 117.0 2DHA9@1|root,32U8X@2|Bacteria,1VD44@1239|Firmicutes,24NC3@186801|Clostridia,222SC@1506553|Lachnoclostridium 186801|Clostridia S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - - k59_82487_10 691965.D4P7C0_9CAUD 2.26e-64 199.0 4QDUR@10239|Viruses,4QVMY@35237|dsDNA viruses no RNA stage,4QU8R@28883|Caudovirales,4QKNQ@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_82487_11 478749.BRYFOR_08531 8.65e-19 82.4 2CGGA@1|root,345NF@2|Bacteria,1VZU0@1239|Firmicutes,253ZW@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_595034_1 1035184.HMPREF1042_1245 2.27e-22 101.0 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,4H9Z7@91061|Bacilli,42E32@671232|Streptococcus anginosus group 91061|Bacilli L DNA polymerase family A - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_82488_1 1041930.Mtc_1683 1.39e-05 54.7 COG0614@1|root,COG1520@1|root,COG1572@1|root,arCOG02483@1|root,arCOG02515@1|root,arCOG03557@1|root,arCOG06792@1|root,arCOG02482@2157|Archaea,arCOG02483@2157|Archaea,arCOG02515@2157|Archaea,arCOG02532@2157|Archaea,arCOG03557@2157|Archaea,arCOG03611@2157|Archaea,arCOG06792@2157|Archaea,2XW0A@28890|Euryarchaeota,2NAJX@224756|Methanomicrobia 224756|Methanomicrobia P Protein of unknown function (DUF3344) - - - - - - - - - - - - CARDB,DUF3344,PKD k59_451583_2 1618259.A0A0C5I2B5_9CIRC 4.98e-100 300.0 4QE84@10239|Viruses,4QUKR@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_492617_2 498742.BSPA14S_0650 6.55e-25 118.0 COG0507@1|root,COG0507@2|Bacteria,2JAK2@203691|Spirochaetes 203691|Spirochaetes L Helicase recD - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,Viral_helicase1 k59_328578_1 5286.M7XIA9 2.59e-12 72.0 COG5265@1|root,KOG0056@2759|Eukaryota,38D03@33154|Opisthokonta,3NV8N@4751|Fungi,3UZ0R@5204|Basidiomycota,2YCWK@29000|Pucciniomycotina 4751|Fungi Q ABC transporter transmembrane region hmt1 GO:0000041,GO:0000166,GO:0000322,GO:0000323,GO:0000324,GO:0000329,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005774,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006857,GO:0006950,GO:0007034,GO:0008144,GO:0008150,GO:0009636,GO:0009987,GO:0010035,GO:0010038,GO:0015399,GO:0015405,GO:0015440,GO:0015711,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030001,GO:0030554,GO:0031090,GO:0031166,GO:0031224,GO:0031300,GO:0031301,GO:0031310,GO:0032553,GO:0032555,GO:0032559,GO:0033220,GO:0034220,GO:0034486,GO:0034635,GO:0034775,GO:0035443,GO:0035639,GO:0035672,GO:0036094,GO:0036246,GO:0036249,GO:0042221,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0042939,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044422,GO:0044424,GO:0044425,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044604,GO:0046686,GO:0050896,GO:0051179,GO:0051181,GO:0051234,GO:0051716,GO:0055085,GO:0061687,GO:0070887,GO:0071241,GO:0071248,GO:0071276,GO:0071585,GO:0071627,GO:0071628,GO:0071702,GO:0071705,GO:0071993,GO:0071994,GO:0071995,GO:0071996,GO:0072337,GO:0072348,GO:0097159,GO:0097237,GO:0097367,GO:0097501,GO:0098588,GO:0098655,GO:0098656,GO:0098660,GO:0098662,GO:0098754,GO:0098805,GO:0098849,GO:0098852,GO:1901265,GO:1901363,GO:1904680,GO:1990170,GO:1990748 - ko:K05661 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1.210 - - ABC_membrane,ABC_tran k59_287463_2 511.JT27_05515 6.1e-33 136.0 COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,2VIPG@28216|Betaproteobacteria,3T8Y5@506|Alcaligenaceae 28216|Betaproteobacteria L Pfam:DUF4102 - - - - - - - - - - - - Arm-DNA-bind_3,Phage_integrase k59_61801_6 889378.Spiaf_2417 4.16e-60 228.0 COG0209@1|root,COG0209@2|Bacteria 2|Bacteria F ribonucleoside-diphosphate reductase activity rtpR - 1.1.98.6,1.17.4.1 ko:K00525,ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024,R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,LAGLIDADG_3,Ribonuc_red_lgC k59_43465_1 879310.HMPREF9162_1725 2.16e-21 99.0 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,4H2EZ@909932|Negativicutes 909932|Negativicutes L DNA polymerase - - - - - - - - - - - - DNA_pol_A k59_249492_2 1177179.A11A3_12968 4.08e-45 162.0 COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,1RMJ1@1236|Gammaproteobacteria,1XP69@135619|Oceanospirillales 135619|Oceanospirillales L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_3,Phage_integrase k59_290093_1 1123507.ATVQ01000001_gene1305 2.23e-39 142.0 COG3023@1|root,COG3023@2|Bacteria,2GJ9M@201174|Actinobacteria,1WBHT@1268|Micrococcaceae 201174|Actinobacteria V Ami_2 - - - - - - - - - - - - Amidase_2 k59_43468_1 1609634.A0A0C5AFV4_9VIRU 8.25e-09 57.4 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_536847_1 1121028.ARQE01000009_gene4195 6.23e-06 56.2 COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,2TRU2@28211|Alphaproteobacteria,2PJDV@255475|Aurantimonadaceae 28211|Alphaproteobacteria K RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,Toprim_4,Toprim_N,zf-CHC2 k59_433693_2 1692249.A0A0K1RLN8_9CIRC 5.51e-29 115.0 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_433693_3 1234881.K0A1K7_9CIRC 9.37e-12 70.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_85349_2 467661.RKLH11_1789 0.000896 50.1 COG3409@1|root,COG3409@2|Bacteria,1RAFU@1224|Proteobacteria,2U9U7@28211|Alphaproteobacteria 28211|Alphaproteobacteria M D-alanyl-D-alanine carboxypeptidase - - - - - - - - - - - - Peptidase_M15_4 k59_351214_1 399739.Pmen_3992 1.95e-28 119.0 28MC2@1|root,2ZAQD@2|Bacteria,1R5I0@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - ParBc k59_331665_1 31234.CRE01053 2.04e-13 75.9 COG0187@1|root,KOG0355@2759|Eukaryota,38CPA@33154|Opisthokonta,3BFVW@33208|Metazoa,3CW22@33213|Bilateria,40BF1@6231|Nematoda,1KXR3@119089|Chromadorea,40WVD@6236|Rhabditida 33208|Metazoa B Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks Top2 GO:0000003,GO:0000070,GO:0000075,GO:0000182,GO:0000217,GO:0000228,GO:0000278,GO:0000280,GO:0000400,GO:0000712,GO:0000785,GO:0000790,GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003690,GO:0003696,GO:0003723,GO:0003729,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0006139,GO:0006259,GO:0006265,GO:0006310,GO:0006323,GO:0006325,GO:0006342,GO:0006355,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007060,GO:0007076,GO:0007093,GO:0007127,GO:0007131,GO:0007140,GO:0007276,GO:0007346,GO:0008094,GO:0008150,GO:0008152,GO:0008623,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016043,GO:0016458,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019953,GO:0022402,GO:0022412,GO:0022414,GO:0030261,GO:0031010,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031570,GO:0031974,GO:0031981,GO:0032501,GO:0032504,GO:0032991,GO:0034641,GO:0035825,GO:0040029,GO:0042623,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043565,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0044703,GO:0044774,GO:0045132,GO:0045786,GO:0045814,GO:0045892,GO:0045930,GO:0045934,GO:0046483,GO:0048232,GO:0048285,GO:0048519,GO:0048523,GO:0048609,GO:0050000,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051252,GO:0051253,GO:0051276,GO:0051303,GO:0051304,GO:0051307,GO:0051310,GO:0051321,GO:0051640,GO:0051641,GO:0051649,GO:0051656,GO:0051704,GO:0051726,GO:0060255,GO:0061505,GO:0061982,GO:0065007,GO:0070013,GO:0070603,GO:0071103,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0098813,GO:0140013,GO:0140014,GO:0140097,GO:1901360,GO:1901363,GO:1902494,GO:1902679,GO:1903046,GO:1903047,GO:1903506,GO:1903507,GO:1904949,GO:1990837,GO:2000112,GO:2000113,GO:2001141 5.99.1.3 ko:K03164 ko01524,map01524 - - - ko00000,ko00001,ko01000,ko03032,ko03036 - - - DNA_gyraseB,DNA_topoisoIV,DTHCT,HATPase_c,TOPRIM_C,Toprim k59_249504_2 1492922.GY26_16080 3.72e-216 618.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,1RP8Z@1236|Gammaproteobacteria,1J8Y8@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_249504_3 571.MC52_01410 0.000158 45.8 COG4695@1|root,COG4695@2|Bacteria,1MUP5@1224|Proteobacteria,1RPB0@1236|Gammaproteobacteria 1236|Gammaproteobacteria S portal protein - - - - - - - - - - - - Phage_portal k59_228190_1 11082.PRO_0000037747 5.72e-83 256.0 4QBXT@10239|Viruses,4R138@439488|ssRNA viruses,4R0R1@35278|ssRNA positive-strand viruses no DNA stage 10239|Viruses K ATP-dependent helicase activity - GO:0000122,GO:0001172,GO:0001510,GO:0001558,GO:0001817,GO:0001818,GO:0001932,GO:0001933,GO:0001934,GO:0001959,GO:0001960,GO:0001961,GO:0002039,GO:0002673,GO:0002674,GO:0002682,GO:0002683,GO:0002694,GO:0002695,GO:0002697,GO:0002698,GO:0002791,GO:0002792,GO:0002831,GO:0002832,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003725,GO:0003727,GO:0003824,GO:0003968,GO:0004175,GO:0004252,GO:0004482,GO:0004483,GO:0005102,GO:0005124,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005793,GO:0006139,GO:0006355,GO:0006357,GO:0006370,GO:0006396,GO:0006397,GO:0006417,GO:0006508,GO:0006725,GO:0006807,GO:0006810,GO:0006897,GO:0006898,GO:0007155,GO:0007159,GO:0008104,GO:0008134,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008171,GO:0008173,GO:0008174,GO:0008233,GO:0008236,GO:0008270,GO:0008284,GO:0008285,GO:0008757,GO:0009058,GO:0009059,GO:0009451,GO:0009452,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010562,GO:0010563,GO:0010564,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0010639,GO:0010646,GO:0010647,GO:0010648,GO:0010692,GO:0010694,GO:0010803,GO:0010804,GO:0010821,GO:0010823,GO:0010921,GO:0010922,GO:0010941,GO:0015031,GO:0015833,GO:0016020,GO:0016032,GO:0016070,GO:0016071,GO:0016192,GO:0016462,GO:0016556,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017016,GO:0017111,GO:0017137,GO:0017151,GO:0017171,GO:0018130,GO:0018995,GO:0019012,GO:0019031,GO:0019048,GO:0019049,GO:0019050,GO:0019054,GO:0019056,GO:0019058,GO:0019065,GO:0019068,GO:0019080,GO:0019082,GO:0019215,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019538,GO:0019899,GO:0019900,GO:0019902,GO:0019903,GO:0020012,GO:0022610,GO:0023051,GO:0023056,GO:0023057,GO:0030162,GO:0030234,GO:0030260,GO:0030307,GO:0030430,GO:0030682,GO:0030683,GO:0030888,GO:0030889,GO:0031072,GO:0031090,GO:0031267,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031329,GO:0031330,GO:0031347,GO:0031348,GO:0031369,GO:0031399,GO:0031400,GO:0031401,GO:0031952,GO:0031953,GO:0032069,GO:0032074,GO:0032101,GO:0032102,GO:0032259,GO:0032268,GO:0032269,GO:0032270,GO:0032386,GO:0032465,GO:0032467,GO:0032675,GO:0032715,GO:0032774,GO:0032780,GO:0032879,GO:0032880,GO:0032944,GO:0032945,GO:0032991,GO:0032993,GO:0033036,GO:0033043,GO:0033116,GO:0033592,GO:0033643,GO:0033644,GO:0033645,GO:0033646,GO:0033647,GO:0033648,GO:0033650,GO:0033655,GO:0033662,GO:0033663,GO:0033668,GO:0033673,GO:0034062,GO:0034121,GO:0034122,GO:0034135,GO:0034136,GO:0034143,GO:0034144,GO:0034155,GO:0034156,GO:0034163,GO:0034164,GO:0034248,GO:0034250,GO:0034641,GO:0034654,GO:0035303,GO:0035306,GO:0035325,GO:0035663,GO:0035821,GO:0036260,GO:0036265,GO:0036338,GO:0039502,GO:0039503,GO:0039506,GO:0039507,GO:0039513,GO:0039516,GO:0039526,GO:0039527,GO:0039547,GO:0039560,GO:0039580,GO:0039584,GO:0039612,GO:0039613,GO:0039644,GO:0039653,GO:0039656,GO:0039657,GO:0039713,GO:0039714,GO:0040008,GO:0042000,GO:0042025,GO:0042127,GO:0042287,GO:0042288,GO:0042325,GO:0042326,GO:0042327,GO:0042509,GO:0042532,GO:0042802,GO:0042886,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043085,GO:0043086,GO:0043122,GO:0043123,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043414,GO:0043462,GO:0043487,GO:0043489,GO:0043549,GO:0043656,GO:0043657,GO:0043900,GO:0043901,GO:0043902,GO:0043903,GO:0044003,GO:0044053,GO:0044068,GO:0044092,GO:0044093,GO:0044164,GO:0044165,GO:0044167,GO:0044177,GO:0044186,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044220,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044279,GO:0044359,GO:0044362,GO:0044403,GO:0044409,GO:0044413,GO:0044414,GO:0044415,GO:0044417,GO:0044419,GO:0044422,GO:0044423,GO:0044424,GO:0044444,GO:0044464,GO:0044501,GO:0044531,GO:0044532,GO:0044766,GO:0044833,GO:0044877,GO:0045069,GO:0045070,GO:0045088,GO:0045184,GO:0045727,GO:0045787,GO:0045824,GO:0045862,GO:0045892,GO:0045927,GO:0045934,GO:0045936,GO:0045937,GO:0046425,GO:0046426,GO:0046483,GO:0046718,GO:0046755,GO:0046762,GO:0046774,GO:0046794,GO:0046872,GO:0046914,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048524,GO:0048583,GO:0048584,GO:0048585,GO:0050670,GO:0050672,GO:0050687,GO:0050688,GO:0050689,GO:0050690,GO:0050691,GO:0050708,GO:0050709,GO:0050727,GO:0050728,GO:0050730,GO:0050732,GO:0050776,GO:0050777,GO:0050789,GO:0050790,GO:0050792,GO:0050794,GO:0050864,GO:0050865,GO:0050866,GO:0050869,GO:0050896,GO:0051020,GO:0051046,GO:0051047,GO:0051048,GO:0051049,GO:0051050,GO:0051051,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051223,GO:0051224,GO:0051234,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051248,GO:0051249,GO:0051250,GO:0051252,GO:0051253,GO:0051302,GO:0051336,GO:0051338,GO:0051345,GO:0051346,GO:0051348,GO:0051701,GO:0051704,GO:0051707,GO:0051726,GO:0051781,GO:0051805,GO:0051806,GO:0051807,GO:0051808,GO:0051817,GO:0051828,GO:0051832,GO:0051833,GO:0051834,GO:0051836,GO:0052026,GO:0052027,GO:0052029,GO:0052031,GO:0052037,GO:0052038,GO:0052040,GO:0052041,GO:0052053,GO:0052055,GO:0052056,GO:0052148,GO:0052150,GO:0052167,GO:0052170,GO:0052173,GO:0052199,GO:0052200,GO:0052203,GO:0052204,GO:0052205,GO:0052230,GO:0052248,GO:0052250,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052312,GO:0052433,GO:0052490,GO:0052493,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0060147,GO:0060149,GO:0060255,GO:0060338,GO:0060339,GO:0060341,GO:0060548,GO:0060589,GO:0060590,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0060759,GO:0060760,GO:0060761,GO:0060966,GO:0060967,GO:0060968,GO:0060969,GO:0065007,GO:0065008,GO:0065009,GO:0070011,GO:0070103,GO:0070104,GO:0070201,GO:0070486,GO:0070663,GO:0070664,GO:0071593,GO:0071702,GO:0071704,GO:0071705,GO:0072583,GO:0075109,GO:0075111,GO:0075112,GO:0075114,GO:0075136,GO:0075344,GO:0075509,GO:0075512,GO:0075528,GO:0080009,GO:0080090,GO:0080134,GO:0080135,GO:0090068,GO:0090087,GO:0090199,GO:0090201,GO:0090304,GO:0097159,GO:0097617,GO:0097659,GO:0097677,GO:0097747,GO:0098588,GO:0098609,GO:0098657,GO:0098772,GO:0106005,GO:0140096,GO:0140098,GO:1900101,GO:1900102,GO:1900117,GO:1900118,GO:1900368,GO:1900369,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901576,GO:1902369,GO:1902531,GO:1902532,GO:1902533,GO:1902579,GO:1902679,GO:1903265,GO:1903506,GO:1903507,GO:1903530,GO:1903531,GO:1903573,GO:1903719,GO:1903721,GO:1903900,GO:1903902,GO:1904892,GO:1904893,GO:1904950,GO:1905897,GO:1990214,GO:1990216,GO:1990219,GO:1990254,GO:1990814,GO:1990904,GO:2000112,GO:2000113,GO:2001141,GO:2001233,GO:2001234 - - - - - - - - - - - k59_105160_1 391625.PPSIR1_33811 9.88e-24 106.0 COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,42N7D@68525|delta/epsilon subdivisions,2WKJS@28221|Deltaproteobacteria,2YTZI@29|Myxococcales 28221|Deltaproteobacteria M Belongs to the peptidase S8 family - - - ko:K14645 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - Peptidase_S8 k59_434426_5 1300345.LF41_1722 1.5e-11 63.5 COG0582@1|root,COG0582@2|Bacteria,1NWGS@1224|Proteobacteria,1S4PB@1236|Gammaproteobacteria,1X89K@135614|Xanthomonadales 135614|Xanthomonadales L Phage integrase family - - - - - - - - - - - - Phage_integrase k59_520550_1 511437.Lbuc_1418 1.34e-32 137.0 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1TSMG@1239|Firmicutes,4HBFH@91061|Bacilli,3F5CJ@33958|Lactobacillaceae 91061|Bacilli S Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C k59_521249_5 1234888.K0A2J2_9VIRU 1.53e-145 433.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_231534_1 224324.aq_1008 4.79e-42 158.0 COG0587@1|root,COG0587@2|Bacteria,2G3PZ@200783|Aquificae 200783|Aquificae L TIGRFAM DNA polymerase III, alpha subunit dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,Intein_splicing,LAGLIDADG_3,PHP,tRNA_anti-codon k59_150107_1 1379717.S5SY19_9CIRC 1.82e-74 238.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_416941_1 1168547.L7P648_9CIRC 1.11e-20 96.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_622474_1 64471.sync_2415 7.79e-21 92.8 2DCYU@1|root,32U0J@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_336439_1 1265845.PWEIH_00500 3.24e-66 216.0 28MC2@1|root,2ZAQD@2|Bacteria,1VSEU@1239|Firmicutes,4HT1S@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k59_89891_1 1121459.AQXE01000023_gene398 9.58e-17 88.6 COG0358@1|root,COG3378@1|root,COG0358@2|Bacteria,COG3378@2|Bacteria,1MV7I@1224|Proteobacteria,42QE4@68525|delta/epsilon subdivisions,2WM1X@28221|Deltaproteobacteria,2MAWM@213115|Desulfovibrionales 28221|Deltaproteobacteria L Poxvirus D5 protein-like - - - ko:K06919 - - - - ko00000 - - - D5_N,Pox_D5,Toprim_2,zf-CHC2 k59_458565_1 1634484.A0A0E3GLN4_9VIRU 4.31e-38 137.0 4QB6C@10239|Viruses 10239|Viruses L Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_644735_6 742733.HMPREF9469_05037 3.18e-13 67.8 2BD7A@1|root,326VE@2|Bacteria,1USRB@1239|Firmicutes,25ASG@186801|Clostridia,223BG@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_339990_5 158500.BV97_02703 3.97e-15 76.3 COG4974@1|root,COG4974@2|Bacteria,1QUTD@1224|Proteobacteria,2TW6U@28211|Alphaproteobacteria,2K7FW@204457|Sphingomonadales 204457|Sphingomonadales L Phage integrase family - - - - - - - - - - - - Phage_integrase k59_234200_1 1234888.K0A2J2_9VIRU 3.29e-71 233.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_152697_1 742740.HMPREF9474_02278 1.52e-18 87.4 28JED@1|root,2Z98K@2|Bacteria,1TW1U@1239|Firmicutes,24CFD@186801|Clostridia,2226E@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - GerE k59_625253_1 269482.Bcep1808_4543 5.12e-26 105.0 2DP75@1|root,330U8@2|Bacteria,1N8XA@1224|Proteobacteria,2VXCX@28216|Betaproteobacteria,1KA22@119060|Burkholderiaceae 28216|Betaproteobacteria L HNH endonuclease - - - - - - - - - - - - AP2,HNH_3 k59_501451_1 332101.JIBU02000048_gene3721 1.48e-46 169.0 COG5545@1|root,COG5545@2|Bacteria,1TQNX@1239|Firmicutes,2495S@186801|Clostridia,36EHX@31979|Clostridiaceae 186801|Clostridia S virulence-associated E family protein - - - - - - - - - - - - VirE k59_194208_1 1327981.S0A2H8_9CAUD 5.81e-36 135.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0019012,GO:0019028,GO:0042802,GO:0044423 - - - - - - - - - - - k59_603798_2 1123037.AUDE01000021_gene2181 1.03e-41 156.0 COG0582@1|root,COG0582@2|Bacteria,4PKC8@976|Bacteroidetes,1HYZC@117743|Flavobacteriia 976|Bacteroidetes L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_5,Phage_int_SAM_5,Phage_integrase k59_356551_3 585394.RHOM_12085 1.93e-19 94.0 2DBCR@1|root,2Z8FA@2|Bacteria,1V8ZT@1239|Firmicutes,24KB5@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_501477_2 211586.SO_4784 0.000269 43.9 2CZQD@1|root,32T6U@2|Bacteria,1N0VG@1224|Proteobacteria,1SB5H@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_340034_1 36875.HQ29_00960 6.37e-06 55.5 COG0323@1|root,COG0323@2|Bacteria,4NHAV@976|Bacteroidetes,2FWGA@200643|Bacteroidia 976|Bacteroidetes L Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - HATPase_c_3 k59_153184_2 63737.Npun_R4417 3.8e-06 53.1 COG0055@1|root,COG0055@2|Bacteria,1G1BK@1117|Cyanobacteria,1HIUK@1161|Nostocales 1117|Cyanobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0016020,GO:0016469,GO:0032991,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_N k59_443033_1 1443665.JACA01000052_gene1878 1.58e-12 77.4 COG0726@1|root,COG2730@1|root,COG3250@1|root,COG4733@1|root,COG0726@2|Bacteria,COG2730@2|Bacteria,COG3250@2|Bacteria,COG4733@2|Bacteria,4NIBG@976|Bacteroidetes,1HYT8@117743|Flavobacteriia,2YJTE@290174|Aquimarina 976|Bacteroidetes G Cellulase (glycosyl hydrolase family 5) - - 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 - R06200,R11307,R11308 - ko00000,ko00001,ko01000 - GH5,GH9 - CBM_6,Cellulase,F5_F8_type_C,fn3 k59_629167_1 187303.BN69_1626 2.08e-31 128.0 COG1475@1|root,COG4725@1|root,COG1475@2|Bacteria,COG4725@2|Bacteria,1R553@1224|Proteobacteria,2TRP6@28211|Alphaproteobacteria,36XZ4@31993|Methylocystaceae 28211|Alphaproteobacteria KT MT-A70 - - - - - - - - - - - - MT-A70,ParBc k59_489913_1 145579.CAPSD_BPPHM 3.99e-41 153.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_260220_1 1048207.F8UBT5_9CAUD 1e-13 70.5 4QH92@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_505079_2 717606.PaecuDRAFT_3108 2.39e-18 82.4 COG1694@1|root,COG1694@2|Bacteria,1VG7F@1239|Firmicutes,4HWVH@91061|Bacilli,26ZEB@186822|Paenibacillaceae 91061|Bacilli S Mazg nucleotide pyrophosphohydrolase - - - - - - - - - - - - MazG k59_629190_2 1147157.K7PJW8_9CAUD 2.2e-37 140.0 4QBV3@10239|Viruses,4QW0W@35237|dsDNA viruses no RNA stage,4QPPJ@28883|Caudovirales,4QKW5@10699|Siphoviridae 10699|Siphoviridae S Phage Terminase - - - - - - - - - - - - - k59_197876_1 641526.ADIWIN_2664 5.35e-33 123.0 2DM6V@1|root,31Z5X@2|Bacteria,4NR9U@976|Bacteroidetes,1I88Y@117743|Flavobacteriia 976|Bacteroidetes S D12 class N6 adenine-specific DNA methyltransferase - - - - - - - - - - - - MethyltransfD12 k59_112879_1 1121895.Q765_03270 4.68e-05 53.5 2EAST@1|root,334US@2|Bacteria,4NRGD@976|Bacteroidetes,1I583@117743|Flavobacteriia,2NU1I@237|Flavobacterium 976|Bacteroidetes - - - - - - - - - - - - - - - k59_112891_2 1313172.YM304_09440 5.93e-22 102.0 COG1061@1|root,COG1061@2|Bacteria,2GIU5@201174|Actinobacteria 201174|Actinobacteria L type III restriction enzyme, res subunit sdrA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - ResIII k59_655292_1 571166.KI421509_gene1198 1.81e-45 161.0 28J3M@1|root,2Z8ZT@2|Bacteria,1Q2A4@1224|Proteobacteria,2TSHZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - PDDEXK_1 k59_179702_1 1692244.A0A0K1RLR5_9CIRC 1.67e-22 100.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_629825_1 1214217.ALNF01000017_gene194 2.28e-40 151.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4H9YP@91061|Bacilli 91061|Bacilli L SNF2 family - - - - - - - - - - - - Helicase_C,SNF2_N k59_424101_1 1618258.A0A0C5I9K3_9CIRC 1.86e-39 145.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_490755_1 91464.S7335_2834 4.36e-51 176.0 COG0030@1|root,COG0030@2|Bacteria,1G03N@1117|Cyanobacteria,1GZ58@1129|Synechococcus 1117|Cyanobacteria J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits ksgA GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - RrnaAD k59_220736_1 546270.GEMHA0001_0918 1.12e-17 84.7 COG0692@1|root,COG0692@2|Bacteria,1TPSN@1239|Firmicutes,4HBTR@91061|Bacilli,3WEDG@539002|Bacillales incertae sedis 91061|Bacilli L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine ung GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k59_20126_1 1618236.A0A0C5I2F3_9CIRC 7.15e-28 116.0 4QGVY@10239|Viruses,4QUKN@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_20126_2 1574422.A0A0A1ENW9_9CIRC 6.3e-58 195.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_20126_3 1676988.A0A0H4FV52_9CIRC 1.86e-24 103.0 4QGVY@10239|Viruses,4QUKN@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_408232_1 49964.Q94MS4_9CAUD 1.1e-95 305.0 4QCUF@10239|Viruses,4QV7U@35237|dsDNA viruses no RNA stage,4QQ89@28883|Caudovirales,4QNCY@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_510515_2 1028307.EAE_08850 1.88e-30 122.0 28H9R@1|root,2Z7MD@2|Bacteria,1MVTR@1224|Proteobacteria,1RMPH@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Psort location Cytoplasmic, score 8.96 - - - - - - - - - - - - DUF932 k59_510515_4 1204521.I6ZXZ4_9CAUD 1.21e-51 179.0 4QHBE@10239|Viruses,4QT2W@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_429854_1 1618236.A0A0C5IB23_9CIRC 1.1e-14 73.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_429854_3 1379719.S5TMX6_9CIRC 2.71e-29 117.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_571937_11 622312.ROSEINA2194_01264 1.25e-36 134.0 COG0270@1|root,COG0270@2|Bacteria,1VSZI@1239|Firmicutes,24YBG@186801|Clostridia 186801|Clostridia L C-5 cytosine-specific DNA methylase - - - - - - - - - - - - DNA_methylase k59_118104_1 323097.Nham_0322 2.68e-35 130.0 COG4712@1|root,COG4712@2|Bacteria,1N9U1@1224|Proteobacteria,2UVCK@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Rad52/22 family double-strand break repair protein - - - - - - - - - - - - Rad52_Rad22 k59_118123_1 1121406.JAEX01000001_gene340 1.28e-26 106.0 COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,42M3X@68525|delta/epsilon subdivisions,2WJDF@28221|Deltaproteobacteria,2M9TD@213115|Desulfovibrionales 28221|Deltaproteobacteria F Catalyzes the reversible phosphorylation of UMP to UDP pyrH GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - - AA_kinase k59_118132_1 1609634.A0A0C5ANA6_9VIRU 1.54e-10 65.1 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_389378_1 1385658.U5KNR1_9VIRU 2.63e-48 167.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_118142_1 504832.OCAR_5533 3.39e-14 71.6 COG0137@1|root,COG0137@2|Bacteria,1MYHX@1224|Proteobacteria,2UJMK@28211|Alphaproteobacteria,3K25M@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Protein of unknown function (DUF2493) - - - - - - - - - - - - DUF2493 k59_429915_2 1236976.JCM16418_2785 1.01e-05 52.4 COG0451@1|root,COG0451@2|Bacteria,1V34Y@1239|Firmicutes,4HCJE@91061|Bacilli,26RRS@186822|Paenibacillaceae 91061|Bacilli GM GDP-mannose 4,6 dehydratase - - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GAF_3,GDP_Man_Dehyd k59_243337_1 1121406.JAEX01000013_gene1261 3.8e-15 85.1 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2WJ3W@28221|Deltaproteobacteria,2M7UN@213115|Desulfovibrionales 28221|Deltaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_409351_1 318586.Pden_2063 6.79e-24 97.1 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2TSDW@28211|Alphaproteobacteria,2PWN8@265|Paracoccus 28211|Alphaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_40469_1 1038860.AXAP01000067_gene8427 1.26e-39 150.0 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,2U6BJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S TIGRFAM phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_119107_2 1540097.A0A0A0YUA7_9CAUD 7.77e-48 161.0 4QGM6@10239|Viruses,4QRH4@28883|Caudovirales,4QP0P@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_371151_1 1708497.A0A0M4F952_9VIRU 8.44e-28 112.0 4QB6C@10239|Viruses 10239|Viruses L Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_84379_1 387631.Asulf_00521 6.36e-14 78.6 COG3979@1|root,COG5306@1|root,arCOG02420@1|root,arCOG03511@1|root,arCOG03553@1|root,arCOG09173@1|root,arCOG02420@2157|Archaea,arCOG03508@2157|Archaea,arCOG03511@2157|Archaea,arCOG03553@2157|Archaea,arCOG07581@2157|Archaea,arCOG09173@2157|Archaea 2157|Archaea C PKD domain containing protein - - - - - - - - - - - - CARDB,DUF2341,PKD,Pilin_N,S_layer_C k59_617715_2 472759.Nhal_1137 1.79e-47 155.0 COG1403@1|root,COG1403@2|Bacteria,1N6FJ@1224|Proteobacteria 1224|Proteobacteria V HNH endonuclease - - - - - - - - - - - - - k59_555707_1 46681.XP_001738227.1 2.4e-07 53.9 2CSEE@1|root,2RBK2@2759|Eukaryota,3X9MH@554915|Amoebozoa 554915|Amoebozoa G RNA helicase - - - - - - - - - - - - RNA_helicase k59_330667_1 1244869.H261_02916 2.59e-09 56.6 arCOG06669@1|root,2ZC1E@2|Bacteria,1RBUZ@1224|Proteobacteria,2UIVS@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_494310_1 582899.Hden_1166 6.96e-25 103.0 COG0175@1|root,COG0175@2|Bacteria,1R52W@1224|Proteobacteria,2U0Y4@28211|Alphaproteobacteria,3N7GH@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria EH COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase and related enzymes - - - - - - - - - - - - PAPS_reduct k59_309190_7 478749.BRYFOR_06507 5.4e-22 90.5 2A2ID@1|root,30QVY@2|Bacteria,1V5QB@1239|Firmicutes,24KQU@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_309190_11 691965.D4P7I0_9CAUD 1.51e-73 235.0 4QDSZ@10239|Viruses,4QXJ8@35237|dsDNA viruses no RNA stage,4QPKE@28883|Caudovirales,4QM8R@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_309190_14 742733.HMPREF9469_05066 4.27e-29 118.0 2EWZQ@1|root,33QB0@2|Bacteria,1V0T1@1239|Firmicutes,249Z2@186801|Clostridia,221YV@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_206529_2 1121887.AUDK01000001_gene527 5.7e-19 91.7 COG2885@1|root,COG2885@2|Bacteria,4NHTP@976|Bacteroidetes,1HZH8@117743|Flavobacteriia,2NUA6@237|Flavobacterium 976|Bacteroidetes M Belongs to the ompA family - - - ko:K03286 - - - - ko00000,ko02000 1.B.6 - - OMP_b-brl,OmpA,TSP_3 k59_371562_1 192952.MM_3038 4.56e-62 210.0 COG0675@1|root,arCOG00684@2157|Archaea,2XSWB@28890|Euryarchaeota,2NAE6@224756|Methanomicrobia 224756|Methanomicrobia L Probable transposase - - - ko:K07496 - - - - ko00000 - - - HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon k59_371562_2 387631.Asulf_02143 1.17e-59 187.0 COG1943@1|root,arCOG02759@2157|Archaea,2XWPT@28890|Euryarchaeota 28890|Euryarchaeota L COG1943 Transposase and inactivated derivatives - - - ko:K07491 - - - - ko00000 - - - Y1_Tnp k59_371562_4 457396.CSBG_03079 1.62e-15 89.7 COG3378@1|root,COG3378@2|Bacteria,1TQP9@1239|Firmicutes,24JCD@186801|Clostridia,36VQB@31979|Clostridiaceae 186801|Clostridia S D5 N terminal like - - - ko:K06919 - - - - ko00000 - - - D5_N k59_536205_1 1120934.KB894461_gene953 1.34e-16 85.9 COG0210@1|root,COG0358@1|root,COG0553@1|root,COG0827@1|root,COG4646@1|root,COG0210@2|Bacteria,COG0358@2|Bacteria,COG0553@2|Bacteria,COG0827@2|Bacteria,COG4646@2|Bacteria,2GU9Z@201174|Actinobacteria,4E9CY@85010|Pseudonocardiales 201174|Actinobacteria L UvrD/REP helicase N-terminal domain - - - - - - - - - - - - AAA_19,Helicase_C,UvrD-helicase,UvrD_C,UvrD_C_2 k59_638920_1 317655.Sala_0708 6.01e-09 63.9 COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,2TSRZ@28211|Alphaproteobacteria,2K052@204457|Sphingomonadales 204457|Sphingomonadales L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 k59_89801_2 1396141.BATP01000029_gene2258 1.04e-32 126.0 2E0FE@1|root,32W1M@2|Bacteria,46TEN@74201|Verrucomicrobia,2IVPU@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Domain of unknown function (DUF932) - - - - - - - - - - - - DUF932 k59_89801_3 870187.Thini_1827 0.000196 44.7 2DMHT@1|root,32RN3@2|Bacteria,1N0KK@1224|Proteobacteria,1TH1D@1236|Gammaproteobacteria,463EV@72273|Thiotrichales 72273|Thiotrichales - - - - - - - - - - - - - - PEGA k59_7224_1 1618247.A0A0C5I2K0_9CIRC 8.44e-12 68.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_644653_1 582899.Hden_1166 3.27e-106 314.0 COG0175@1|root,COG0175@2|Bacteria,1R52W@1224|Proteobacteria,2U0Y4@28211|Alphaproteobacteria,3N7GH@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria EH COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase and related enzymes - - - - - - - - - - - - PAPS_reduct k59_89817_1 1101189.AQUO01000001_gene1434 7.19e-40 151.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2TSDW@28211|Alphaproteobacteria,2PWI6@265|Paracoccus 28211|Alphaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_150070_1 1224136.AMFN01000003_gene3608 5.25e-12 63.5 COG3772@1|root,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,1S99W@1236|Gammaproteobacteria 1236|Gammaproteobacteria G lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_498783_1 1449976.KALB_6064 0.000894 43.9 COG0741@1|root,COG0741@2|Bacteria,2IGMV@201174|Actinobacteria,4E6UR@85010|Pseudonocardiales 201174|Actinobacteria M Transglycosylase SLT domain - - - - - - - - - - - - PG_binding_1,SLT,T7SS_ESX_EspC k59_498783_5 1556290.A0A0A0RM05_9CAUD 2.88e-191 551.0 4QAYV@10239|Viruses,4QPU3@28883|Caudovirales,4QKKX@10699|Siphoviridae 10699|Siphoviridae S Phage portal protein - - - - - - - - - - - - - k59_498783_7 1556290.A0A0A0RL61_9CAUD 1.14e-115 342.0 4QAK6@10239|Viruses,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - GO:0005575,GO:0019012,GO:0019028,GO:0032991,GO:0044423,GO:0046806 - - - - - - - - - - - k59_68310_3 1410638.JHXJ01000001_gene1735 1.92e-13 68.6 COG0758@1|root,COG0758@2|Bacteria,1VNFT@1239|Firmicutes,24S79@186801|Clostridia,3WMKC@541000|Ruminococcaceae 186801|Clostridia LU Protein of unknown function (DUF2493) - - - - - - - - - - - - DUF2493 k59_560138_1 927658.AJUM01000047_gene2931 1.86e-71 230.0 COG0042@1|root,COG0042@2|Bacteria,4NEMR@976|Bacteroidetes,2FRWE@200643|Bacteroidia,3XJHB@558415|Marinilabiliaceae 976|Bacteroidetes J Dihydrouridine synthase (Dus) - - - - - - - - - - - - Dus k59_416904_1 1353529.M899_2645 0.000597 47.4 COG3210@1|root,COG3420@1|root,COG3210@2|Bacteria,COG3420@2|Bacteria,1NED3@1224|Proteobacteria,42WDX@68525|delta/epsilon subdivisions,2MTVC@213481|Bdellovibrionales,2WRDH@28221|Deltaproteobacteria 213481|Bdellovibrionales U cell wall surface anchor family protein - - - - - - - - - - - - Peptidase_S74 k59_171490_1 691965.D4P7I3_9CAUD 4.43e-141 439.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_480767_2 999550.KI421507_gene3808 1.04e-51 172.0 COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,2TU8N@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_644680_4 1227453.C444_08940 2.2e-16 83.2 COG0286@1|root,arCOG02632@2157|Archaea,2Y0X4@28890|Euryarchaeota,23XY7@183963|Halobacteria 183963|Halobacteria V COG0286 Type I restriction-modification system methyltransferase subunit - - - - - - - - - - - - N6_Mtase k59_210196_1 1122201.AUAZ01000017_gene2950 3.35e-54 182.0 COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,1RY1X@1236|Gammaproteobacteria,46BED@72275|Alteromonadaceae 1236|Gammaproteobacteria S associated with various cellular activities - - - - - - - - - - - - AAA,AAA_5 k59_541553_2 794846.AJQU01000075_gene3402 3.94e-06 59.7 2DQJ1@1|root,3376F@2|Bacteria,1RKWB@1224|Proteobacteria,2UA4H@28211|Alphaproteobacteria,4BE0C@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - Beta_helix,Pectate_lyase_3 k59_337056_1 1234888.K0A2J2_9VIRU 5.76e-41 149.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_444256_1 742740.HMPREF9474_02271 5.67e-76 241.0 28J3N@1|root,2Z8ZU@2|Bacteria,1V15Z@1239|Firmicutes,249Z0@186801|Clostridia,221RR@1506553|Lachnoclostridium 186801|Clostridia S Phage portal protein - - - - - - - - - - - - Phage_portal k59_72251_1 232237.Q7Y5K0_9CAUD 2.59e-15 79.0 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales,4QKM7@10699|Siphoviridae 10699|Siphoviridae S HNH endonuclease - - - - - - - - - - - - - k59_626657_3 1203554.HMPREF1476_00420 2.63e-11 60.5 COG1328@1|root,COG1328@2|Bacteria,1N8MB@1224|Proteobacteria,2VW43@28216|Betaproteobacteria,4PRD8@995019|Sutterellaceae 28216|Betaproteobacteria F Anaerobic ribonucleoside-triphosphate reductase - - - - - - - - - - - - NRDD k59_213649_1 1234888.K0A2J2_9VIRU 3.96e-51 178.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_258212_1 762982.HMPREF9442_01223 6.28e-23 100.0 COG0270@1|root,COG0270@2|Bacteria,4NJPP@976|Bacteroidetes,2FKYT@200643|Bacteroidia 976|Bacteroidetes H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_277585_1 626887.J057_01785 2.57e-30 122.0 2DCM2@1|root,32TZV@2|Bacteria,1NAGE@1224|Proteobacteria,1SMRS@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_277585_2 691965.D4P7B9_9CAUD 2.43e-31 113.0 4QFDH@10239|Viruses,4QWV5@35237|dsDNA viruses no RNA stage,4QPB8@28883|Caudovirales,4QKNN@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_176724_3 96561.Dole_0853 1.15e-05 46.2 arCOG06669@1|root,2ZC1E@2|Bacteria,1RBUZ@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_527785_1 1437882.AZRU01000034_gene457 2.45e-26 103.0 COG2197@1|root,COG2197@2|Bacteria,1NA3X@1224|Proteobacteria 1224|Proteobacteria KT HNH endonuclease - - - - - - - - - - - - HNH_3 k59_564787_1 644107.SL1157_2140 7.09e-07 58.2 COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria 2|Bacteria D nuclear chromosome segregation - - - - - - - - - - - - PhageMin_Tail,TMP_2,Tape_meas_lam_C k59_214068_1 1121115.AXVN01000082_gene2996 1.27e-09 65.1 COG4548@1|root,COG4548@2|Bacteria,1TPW1@1239|Firmicutes,24ASV@186801|Clostridia,3XYZT@572511|Blautia 186801|Clostridia P Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - CobT_C k59_463664_1 164328.Phyra73454 1.07e-69 231.0 COG1372@1|root,2QRRC@2759|Eukaryota,3Q9PN@4776|Peronosporales 4776|Peronosporales L reductase - - - - - - - - - - - - - k59_258252_2 1305737.JAFX01000001_gene2992 1.45e-28 117.0 COG1233@1|root,COG1233@2|Bacteria,4NG7V@976|Bacteroidetes,47MT8@768503|Cytophagia 976|Bacteroidetes Q phytoene crtI - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 - R04787,R04798,R04800,R09691,R09692 RC01214,RC02088,RC02605 ko00000,ko00001,ko01000 - - - Amino_oxidase k59_116805_4 1122973.KB904242_gene570 3.88e-07 56.6 COG0582@1|root,COG0582@2|Bacteria,4NF9Q@976|Bacteroidetes,2FQ40@200643|Bacteroidia 976|Bacteroidetes L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_int_SAM_3,Phage_integrase k59_202475_2 1796001.A0A140CTP2_9CIRC 7.83e-49 163.0 4QB6C@10239|Viruses 10239|Viruses L Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_183668_2 1095750.HMPREF9970_1019 0.000264 43.1 COG2887@1|root,COG2887@2|Bacteria,1TPIC@1239|Firmicutes,247TB@186801|Clostridia 186801|Clostridia L Psort location Cytoplasmic, score - - - - - - - - - - - - DUF2800 k59_304913_1 1476391.X5L4M4_9CAUD 6.87e-33 131.0 4QBY0@10239|Viruses,4QW35@35237|dsDNA viruses no RNA stage,4QQ4Q@28883|Caudovirales,4QNNN@10744|Podoviridae 10744|Podoviridae S UvrD-like helicase C-terminal domain - - - - - - - - - - - - - k59_509525_1 1433126.BN938_2585 8.7e-60 199.0 COG0863@1|root,COG0863@2|Bacteria,4NID2@976|Bacteroidetes,2FV9W@200643|Bacteroidia 976|Bacteroidetes L DNA methylase - - 2.1.1.113 ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_183695_2 1618236.A0A0C5I2F3_9CIRC 2.89e-56 194.0 4QGVY@10239|Viruses,4QUKN@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_37907_2 388051.AUFE01000035_gene4020 2.02e-17 84.0 COG4653@1|root,COG4653@2|Bacteria 2|Bacteria G Phage capsid family - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_265390_1 382640.BT_0527 7.15e-26 108.0 COG3646@1|root,COG3646@2|Bacteria,1N7SM@1224|Proteobacteria,2TY95@28211|Alphaproteobacteria,48UQH@772|Bartonellaceae 28211|Alphaproteobacteria S protein HI1412 of Haemophilus influenzae (P45197) - - - - - - - - - - - - Phage_pRha k59_592664_1 1234888.K0A2J2_9VIRU 5.91e-69 227.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_21786_1 553207.HMPREF0299_5229 2.95e-26 107.0 COG2189@1|root,COG2189@2|Bacteria 2|Bacteria L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.72,3.1.21.3 ko:K01154,ko:K03933,ko:K07316 - - - - ko00000,ko01000,ko02048 - AA10,CBM73 - MethyltransfD12,N6_N4_Mtase,PT k59_21786_3 990285.RGCCGE502_04825 4.51e-09 64.3 COG2189@1|root,COG2189@2|Bacteria,1MX9M@1224|Proteobacteria,2TSW9@28211|Alphaproteobacteria,4B8SP@82115|Rhizobiaceae 28211|Alphaproteobacteria L Belongs to the N(4) N(6)-methyltransferase family ccrM - 2.1.1.72 ko:K13581 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko02048 - - - N6_N4_Mtase k59_205715_1 1560342.A0A0A0RLS5_9CAUD 2.4e-54 200.0 4QCHF@10239|Viruses,4QPIH@28883|Caudovirales,4QHVS@10662|Myoviridae 10662|Myoviridae S PhoH-like protein - - - - - - - - - - - - - k59_165556_1 1537917.JU82_06570 2.07e-32 119.0 2CGG9@1|root,2ZVSJ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_165556_2 691965.D4P7D9_9CAUD 7.09e-29 115.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_288567_1 1445714.W0LNL3_9CAUD 4.52e-39 144.0 4QB79@10239|Viruses,4QX2S@35237|dsDNA viruses no RNA stage,4QS2C@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_596073_1 749222.Nitsa_1810 5.38e-68 213.0 2C2E9@1|root,32RAA@2|Bacteria,1RF5M@1224|Proteobacteria,433I8@68525|delta/epsilon subdivisions 1224|Proteobacteria - - - - - - - - - - - - - - - k59_575929_2 1262914.BN533_00794 2.55e-42 157.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4H2W4@909932|Negativicutes 909932|Negativicutes L SNF2 family - - - - - - - - - - - - Helicase_C,SNF2_N k59_473665_1 1229760.K4I381_9CAUD 9.71e-11 68.9 4QAPV@10239|Viruses,4QV7H@35237|dsDNA viruses no RNA stage,4QQ0U@28883|Caudovirales,4QHZK@10662|Myoviridae 10662|Myoviridae S regulation of transcription, DNA-dependent - - - - - - - - - - - - - k59_473665_2 1525715.IX54_15005 1.06e-09 62.8 COG3740@1|root,COG3740@2|Bacteria,1N2D8@1224|Proteobacteria,2UD3U@28211|Alphaproteobacteria,2PW5G@265|Paracoccus 28211|Alphaproteobacteria S Caudovirus prohead serine protease - - - ko:K06904 - - - - ko00000 - - - Peptidase_S78 k59_432078_1 105154.Q9MBU6_9VIRU 2.47e-80 259.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_1762_1 1073754.G0ZNE5_9VIRU 6.25e-24 99.4 4QAIU@10239|Viruses 10239|Viruses S HNH endonuclease - - - - - - - - - - - - - k59_411763_1 1463920.JOGB01000045_gene2826 1.89e-17 87.8 COG4932@1|root,COG4932@2|Bacteria,2IFAA@201174|Actinobacteria 201174|Actinobacteria M domain protein - - - - - - - - - - - - - k59_308880_1 500635.MITSMUL_03105 2.1e-13 75.1 COG0756@1|root,COG0756@2|Bacteria,1U4S1@1239|Firmicutes,4H64B@909932|Negativicutes 909932|Negativicutes F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA - - 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase k59_370592_1 1618241.A0A0C5I2I4_9CIRC 1.96e-84 258.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_370592_3 1618241.A0A0C5I2I4_9CIRC 1.7e-11 68.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_391391_1 41431.PCC8801_4296 1.02e-10 67.0 COG0270@1|root,COG0270@2|Bacteria,1G288@1117|Cyanobacteria 1117|Cyanobacteria H PFAM C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_391391_2 585394.RHOM_12995 5.82e-08 56.2 COG2189@1|root,COG2189@2|Bacteria,1TR8A@1239|Firmicutes,249A1@186801|Clostridia 186801|Clostridia L PFAM DNA methylase N-4 N-6 domain protein - - 2.1.1.72 ko:K00571,ko:K07316 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_83899_2 1788454.A0A190WHE4_9CIRC 3.75e-16 78.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_1763_1 1122201.AUAZ01000017_gene2947 9.94e-71 248.0 COG0749@1|root,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,465DD@72275|Alteromonadaceae 1236|Gammaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity - - - - - - - - - - - - DNA_pol_A k59_1763_3 1122201.AUAZ01000017_gene2947 3.6e-135 415.0 COG0749@1|root,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,465DD@72275|Alteromonadaceae 1236|Gammaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity - - - - - - - - - - - - DNA_pol_A k59_642207_1 537007.BLAHAN_05507 4.57e-95 282.0 COG0863@1|root,COG0863@2|Bacteria,1V0ZF@1239|Firmicutes,24CQV@186801|Clostridia 186801|Clostridia L Belongs to the N(4) N(6)-methyltransferase family - - - - - - - - - - - - N6_N4_Mtase k59_579099_2 318464.IO99_02985 2.41e-08 60.5 COG2896@1|root,COG2896@2|Bacteria,1TP89@1239|Firmicutes,247PP@186801|Clostridia,36EQA@31979|Clostridiaceae 186801|Clostridia H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate moaA - 4.1.99.22 ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09394 RC03420 ko00000,ko00001,ko01000 - - - Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM k59_229943_5 314271.RB2654_05280 4.42e-13 77.0 COG5281@1|root,COG5281@2|Bacteria,1R47M@1224|Proteobacteria,2TUIV@28211|Alphaproteobacteria 28211|Alphaproteobacteria S COG5281, Phage-related minor tail protein - - - - - - - - - - - - - k59_229943_7 398525.KB900701_gene5079 4.72e-09 58.5 COG0791@1|root,COG0791@2|Bacteria,1N732@1224|Proteobacteria,2UH6X@28211|Alphaproteobacteria,3K18Y@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M NlpC/P60 family - - - - - - - - - - - - NLPC_P60 k59_229943_8 265072.Mfla_2685 7.78e-11 74.7 COG4733@1|root,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria,2VJEP@28216|Betaproteobacteria 28216|Betaproteobacteria NT Phage-related protein, tail - - - - - - - - - - - - DUF1983,Phage-tail_3 k59_87774_1 1238186.AOCN01000019_gene398 1.46e-56 212.0 COG0553@1|root,COG0553@2|Bacteria,2GISC@201174|Actinobacteria,4FM8B@85023|Microbacteriaceae 201174|Actinobacteria L SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,SNF2_N k59_5484_1 1206735.BAGG01000249_gene6011 9.47e-15 80.1 COG0392@1|root,COG0671@1|root,COG3642@1|root,COG0392@2|Bacteria,COG0671@2|Bacteria,COG3642@2|Bacteria,2GMAV@201174|Actinobacteria,4FXZC@85025|Nocardiaceae 201174|Actinobacteria IT Lysylphosphatidylglycerol synthase TM region - - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - LPG_synthase_TM,PAP2 k59_271437_1 1788452.A0A190WHG0_9CIRC 2.96e-22 97.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_599557_1 1109717.G9FGV8_9CAUD 2.96e-21 102.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_415173_1 278963.ATWD01000001_gene4141 2.61e-28 114.0 COG4227@1|root,COG4227@2|Bacteria,3Y6Y0@57723|Acidobacteria,2JMEW@204432|Acidobacteriia 204432|Acidobacteriia L Domain of unknown function (DUF1738) - - - - - - - - - - - - DUF1738 k59_518992_1 1406793.U5PT82_9CAUD 6.67e-05 49.3 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales 28883|Caudovirales S N-acetylmuramoyl-L-alanine amidase activity - - - - - - - - - - - - - k59_599579_1 1144312.PMI09_00682 1.35e-08 61.2 COG5301@1|root,COG5301@2|Bacteria,1R22J@1224|Proteobacteria,2TZ94@28211|Alphaproteobacteria 28211|Alphaproteobacteria G cellulose 1,4-beta-cellobiosidase activity - - - - - - - - - - - - - k59_5938_1 1122175.ATXU01000013_gene498 2.95e-05 52.4 COG1475@1|root,COG1475@2|Bacteria,2HTYC@201174|Actinobacteria,4FM7Z@85023|Microbacteriaceae 201174|Actinobacteria K ParB-like nuclease domain - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_45464_1 1538804.A0A088FAQ4_9CAUD 5.41e-33 125.0 4QCT7@10239|Viruses,4QPFU@28883|Caudovirales,4QKS9@10699|Siphoviridae 10699|Siphoviridae S iron-sulfur cluster binding - - - - - - - - - - - - - k59_174341_3 1618238.A0A0C5IB41_9CIRC 1.86e-07 58.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_132942_1 582402.Hbal_0007 1.34e-21 97.1 COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,2TQPK@28211|Alphaproteobacteria,43X47@69657|Hyphomonadaceae 28211|Alphaproteobacteria J due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 k59_109242_1 298654.FraEuI1c_7061 2.84e-05 55.1 2EJNR@1|root,33DDM@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Peptidase_S74 k59_70787_1 93220.LV28_05180 1.96e-72 228.0 COG0302@1|root,COG0302@2|Bacteria,1MY3N@1224|Proteobacteria,2VH10@28216|Betaproteobacteria,1K0A7@119060|Burkholderiaceae 28216|Betaproteobacteria H GTP cyclohydrolase folE - 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydroI k59_297277_1 240292.Ava_4870 0.000185 43.5 COG2336@1|root,COG2336@2|Bacteria,1G9A5@1117|Cyanobacteria,1HPNY@1161|Nostocales 1117|Cyanobacteria T SpoVT / AbrB like domain - - - ko:K07172 - - - - ko00000,ko02048 - - - MazE_antitoxin k59_604175_2 1151292.QEW_4647 8.37e-06 52.0 COG0791@1|root,COG1388@1|root,COG4193@1|root,COG0791@2|Bacteria,COG1388@2|Bacteria,COG4193@2|Bacteria,1UMD7@1239|Firmicutes,25GF2@186801|Clostridia 186801|Clostridia M SH3, type 3 domain protein - - - - - - - - - - - - Cu_amine_oxidN1,LysM,SH3_3 k59_604175_3 556269.ACDQ01000003_gene1356 5.95e-11 73.6 COG4733@1|root,COG4733@2|Bacteria,1PG9M@1224|Proteobacteria,2W1MG@28216|Betaproteobacteria,4782D@75682|Oxalobacteraceae 28216|Betaproteobacteria S cellulase activity - - - - - - - - - - - - - k59_30008_1 1121937.AUHJ01000018_gene206 2.21e-16 84.3 COG0582@1|root,COG0582@2|Bacteria,1N2H9@1224|Proteobacteria,1RYEY@1236|Gammaproteobacteria,46A5F@72275|Alteromonadaceae 1236|Gammaproteobacteria L Pfam:DUF4102 - - - - - - - - - - - - Arm-DNA-bind_3,Phage_int_SAM_1,Phage_integrase k59_10540_2 1009370.ALO_09559 4.43e-15 75.1 COG2340@1|root,COG2340@2|Bacteria,1V6GZ@1239|Firmicutes,4H4BG@909932|Negativicutes 909932|Negativicutes S Cysteine-rich secretory protein family - - - - - - - - - - - - CAP k59_10540_3 883066.HMPREF9233_00128 8.21e-05 44.7 COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4D33G@85005|Actinomycetales 201174|Actinobacteria L DNA-directed DNA polymerase dnaE GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k59_379115_1 1324957.K933_09627 5.29e-27 117.0 COG3378@1|root,arCOG08578@1|root,arCOG06914@2157|Archaea,arCOG08578@2157|Archaea,2XYEY@28890|Euryarchaeota,23WKP@183963|Halobacteria 183963|Halobacteria S Phage plasmid primase, P4 family - - - ko:K06919 - - - - ko00000 - - - D5_N k59_501874_1 416269.APL_0148 4.52e-75 243.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,1RMPV@1236|Gammaproteobacteria,1Y7PP@135625|Pasteurellales 135625|Pasteurellales F Ribonucleotide reductase, alpha subunit - - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_lgC k59_583996_1 186617.M9M8L2_9VIRU 9.83e-32 132.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_420249_1 1123487.KB892865_gene1394 5.87e-35 135.0 COG0749@1|root,COG0749@2|Bacteria,1MWX7@1224|Proteobacteria,2VMZW@28216|Betaproteobacteria 28216|Betaproteobacteria L DNA polymerase family A - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_94209_1 1122201.AUAZ01000017_gene2950 1.9e-30 117.0 COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,1RY1X@1236|Gammaproteobacteria,46BED@72275|Alteromonadaceae 1236|Gammaproteobacteria S associated with various cellular activities - - - - - - - - - - - - AAA,AAA_5 k59_525628_2 873449.STRCR_0440 6.9e-11 66.6 COG3883@1|root,COG3942@1|root,COG3883@2|Bacteria,COG3942@2|Bacteria 2|Bacteria S pathogenesis usp - 3.5.1.28 ko:K21471,ko:K22409 - - - - ko00000,ko01000,ko01002,ko01011 - CBM50 - CHAP,LysM,NLPC_P60 k59_485186_2 1340826.S5Z5D6_9CAUD 3.19e-16 77.0 4QUTY@35237|dsDNA viruses no RNA stage,4QM17@10699|Siphoviridae 10699|Siphoviridae S Protein of unknwon function (DUF3310) - - - - - - - - - - - - - k59_584022_1 1234888.K0A2J2_9VIRU 2.29e-54 188.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_49310_1 1234888.K0A2J2_9VIRU 6.1e-140 417.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_360498_1 1379715.S5TMW6_9CIRC 9.7e-10 59.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_100510_1 626418.bglu_1g23810 6.77e-11 67.4 COG0790@1|root,COG0790@2|Bacteria 2|Bacteria S beta-lactamase activity - - 3.1.1.32,3.1.1.4 ko:K01058,ko:K07502 ko00564,ko00565,ko00590,ko00591,ko00592,ko01100,ko01110,map00564,map00565,map00590,map00591,map00592,map01100,map01110 - R01315,R01316,R01317,R02053,R02054,R04034,R07064,R07379,R07387,R07859,R07860 RC00020,RC00037,RC00041,RC00094 ko00000,ko00001,ko01000 - - - DUF2911,PEGA,T5orf172 k59_100539_1 717231.Flexsi_2224 1.22e-14 79.0 COG0507@1|root,COG0507@2|Bacteria,2GFD3@200930|Deferribacteres 200930|Deferribacteres L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD recD - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,UvrD_C_2 k59_630294_1 859653.HIMB5_00011180 1.08e-10 68.9 COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2TSCY@28211|Alphaproteobacteria,4BQ84@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria E TIGRFAM asparagine synthase (glutamine-hydrolyzing) - - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 k59_567494_1 172088.AUGA01000082_gene6217 4.3e-09 60.8 COG3740@1|root,COG3740@2|Bacteria,1NBQ9@1224|Proteobacteria,2UK6T@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Caudovirus prohead serine protease - - - - - - - - - - - - Peptidase_S78 k59_199290_2 1101192.KB910516_gene3504 1.34e-12 68.2 COG5281@1|root,COG5281@2|Bacteria,1R47M@1224|Proteobacteria,2TUIV@28211|Alphaproteobacteria,1JV0F@119045|Methylobacteriaceae 28211|Alphaproteobacteria S COG5281, Phage-related minor tail protein - - - - - - - - - - - - - k59_384107_1 227470.Q76YY3_9CAUD 8.23e-07 51.2 4QC1M@10239|Viruses,4R055@35237|dsDNA viruses no RNA stage,4QQ4W@28883|Caudovirales,4QJAV@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_286715_2 1345695.CLSA_c30140 5.96e-05 44.7 2DR9Y@1|root,33AUY@2|Bacteria,1VEP1@1239|Firmicutes,24SWA@186801|Clostridia,36NAT@31979|Clostridiaceae 186801|Clostridia V NUMOD4 motif - - - - - - - - - - - - HNH_3,NUMOD4 k59_533195_2 105154.Q9MBU3_9VIRU 1.6e-07 57.8 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_635714_1 1788455.A0A190WHF5_9CIRC 7.76e-68 218.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_143592_1 1121865.OMW_01016 5.22e-33 140.0 COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,4H9T3@91061|Bacilli,4B07H@81852|Enterococcaceae 91061|Bacilli L DNA polymerase alpha chain like domain dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k59_574202_3 186617.M9M8L2_9VIRU 4.17e-17 80.9 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_164113_2 1129192.A0A0E3D9T0_9CAUD 2.29e-21 93.6 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales,4QI6J@10662|Myoviridae 10662|Myoviridae S sequence-specific DNA binding transcription factor activity - - - - - - - - - - - - - k59_287132_2 1618248.A0A0C5IB82_9CIRC 3.36e-95 290.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_389673_1 1269813.ATUL01000006_gene1804 1.61e-15 85.1 COG1511@1|root,COG5281@1|root,COG1511@2|Bacteria,COG5281@2|Bacteria,1R1X9@1224|Proteobacteria 1224|Proteobacteria S domain protein - - - - - - - - - - - - - k59_430651_2 411460.RUMTOR_01342 8.86e-67 209.0 28NM4@1|root,2ZBMQ@2|Bacteria,1V1QD@1239|Firmicutes,24G1B@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_594702_1 2003327.CAPSD_BPCHP 1.22e-07 53.9 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_22912_1 1618237.A0A0C5IMG6_9CIRC 1.5e-10 65.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_432991_2 1406780.U5PZS8_9CAUD 4.69e-07 50.4 4QGGR@10239|Viruses,4QZHR@35237|dsDNA viruses no RNA stage,4QUGZ@28883|Caudovirales,4QNY3@10744|Podoviridae 10744|Podoviridae S viral capsid - - - - - - - - - - - - - k59_2706_1 765910.MARPU_05580 1.59e-71 228.0 COG3723@1|root,COG3723@2|Bacteria,1R6DB@1224|Proteobacteria,1RZZ3@1236|Gammaproteobacteria 1236|Gammaproteobacteria L COG3723 Recombinational DNA repair protein (RecE pathway) recT GO:0000724,GO:0000725,GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0018130,GO:0019438,GO:0032392,GO:0032508,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043150,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071704,GO:0071840,GO:0071897,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - ko:K07455 - - - - ko00000,ko03400 - - - RecT k59_331125_1 1205681.CALW02000066_gene568 1.17e-19 95.9 COG4733@1|root,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria,2TV2W@28211|Alphaproteobacteria 28211|Alphaproteobacteria S COG4733 Phage-related protein, tail component - - - - - - - - - - - - Phage-tail_3 k59_269207_2 575540.Isop_2435 1.86e-22 103.0 COG5511@1|root,COG5511@2|Bacteria,2IZFA@203682|Planctomycetes 203682|Planctomycetes S Phage portal protein, lambda family - - - - - - - - - - - - Phage_portal_2 k59_43165_2 2003327.CAPSD_BPCHP 2.57e-63 212.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_309475_1 1788443.A0A190WHB4_9CIRC 1.35e-06 55.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_392225_2 1131266.ARWQ01000001_gene1242 1.13e-10 74.3 COG1287@1|root,arCOG02043@2157|Archaea,arCOG02044@2157|Archaea,41SBI@651137|Thaumarchaeota 651137|Thaumarchaeota G Oligosaccharyl transferase STT3 subunit - - 2.4.99.18 ko:K07151 ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141 M00072 R04216,R05976 RC00005,RC00482 ko00000,ko00001,ko00002,ko01000,ko01003 - GT66 - STT3 k59_392225_4 118168.MC7420_7380 3.37e-14 80.5 COG1215@1|root,COG1215@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Glyco_trans_2_3,Glycos_transf_1,Glycos_transf_2 k59_618455_4 135651.CBN12547 3.37e-22 114.0 29JZG@1|root,2RT8A@2759|Eukaryota,38VFU@33154|Opisthokonta,3C5VR@33208|Metazoa,3DKXY@33213|Bilateria,40IHK@6231|Nematoda,1M1T3@119089|Chromadorea,414WI@6236|Rhabditida 33208|Metazoa - - - - - - - - - - - - - - - k59_412921_2 1538804.A0A088F6N3_9CAUD 6.31e-19 84.0 4QFW7@10239|Viruses,4QU0S@28883|Caudovirales,4QM9S@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_3111_1 460265.Mnod_4078 1.11e-37 146.0 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,2U6BJ@28211|Alphaproteobacteria,1JZ7Y@119045|Methylobacteriaceae 28211|Alphaproteobacteria S TIGRFAM phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_558837_1 1325372.N0DPG8_9CAUD 1.77e-18 85.9 4QBHW@10239|Viruses,4QW8N@35237|dsDNA viruses no RNA stage,4QTT7@28883|Caudovirales,4QJZQ@10662|Myoviridae 10662|Myoviridae S sequence-specific DNA binding transcription factor activity - - - - - - - - - - - - - k59_169990_1 1692259.A0A0K1RL59_9CIRC 3.58e-11 67.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_600328_2 103372.F4WEQ8 8.06e-07 55.1 2CXGH@1|root,2RX9T@2759|Eukaryota,39YTV@33154|Opisthokonta,3BMVG@33208|Metazoa,3DDBX@33213|Bilateria,42250@6656|Arthropoda,3SITN@50557|Insecta,46M7W@7399|Hymenoptera 33208|Metazoa - - - - - - - - - - - - - - Parvo_coat_N k59_643276_1 697281.Mahau_0585 0.000333 47.4 COG3941@1|root,COG3941@2|Bacteria,1V33U@1239|Firmicutes,24S63@186801|Clostridia,42GAX@68295|Thermoanaerobacterales 186801|Clostridia S tape measure - - - - - - - - - - - - - k59_394987_1 1379698.RBG1_1C00001G1620 3.39e-38 142.0 COG2222@1|root,COG2222@2|Bacteria,2NQVV@2323|unclassified Bacteria 2|Bacteria M Bacterial phospho-glucose isomerase C-terminal SIS domain pgi - 5.3.1.8,5.3.1.9 ko:K15916 ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R01819,R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000 - - - SIS,bact-PGI_C k59_190284_2 1218084.BBJK01000019_gene2008 2.7e-31 117.0 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,2VR2Z@28216|Betaproteobacteria,1K2Q6@119060|Burkholderiaceae 28216|Betaproteobacteria L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_415978_2 1555208.A0A097EW09_9CAUD 1.31e-22 107.0 4QCW3@10239|Viruses,4QRS3@28883|Caudovirales,4QMID@10699|Siphoviridae 10699|Siphoviridae S Peptidase family S49 - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0018995,GO:0019012,GO:0030430,GO:0033643,GO:0033646,GO:0042802,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_395003_1 1461580.CCAS010000067_gene4013 1.94e-06 57.8 2DKV2@1|root,30F83@2|Bacteria,1V1YU@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - k59_129076_2 1121106.JQKB01000009_gene241 1.77e-35 147.0 COG1061@1|root,COG1061@2|Bacteria,1Q7YV@1224|Proteobacteria,2U3NE@28211|Alphaproteobacteria 28211|Alphaproteobacteria KL PFAM type III restriction protein res subunit - - - - - - - - - - - - ResIII k59_600339_3 287.DR97_4255 4.1e-07 61.6 COG5511@1|root,COG5511@2|Bacteria,1MVN4@1224|Proteobacteria,1RRK4@1236|Gammaproteobacteria 1236|Gammaproteobacteria S portal protein - - - - - - - - - - - - Phage_portal_2 k59_415991_2 186617.M9M8L2_9VIRU 1.84e-21 96.7 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_479591_1 1075090.GOAMR_06_01010 2.22e-62 204.0 COG1403@1|root,COG1479@1|root,COG1403@2|Bacteria,COG1479@2|Bacteria,2IE40@201174|Actinobacteria 201174|Actinobacteria V HNH endonuclease - - - - - - - - - - - - DUF262,HNH k59_643350_1 748280.NH8B_1855 5.14e-29 123.0 COG3598@1|root,COG4983@1|root,COG3598@2|Bacteria,COG4983@2|Bacteria,1R4EA@1224|Proteobacteria,2VKG4@28216|Betaproteobacteria 28216|Betaproteobacteria L AAA domain - - - - - - - - - - - - AAA_25,PriCT_2 k59_315682_1 1476390.A0A060RF85_9CAUD 5.12e-28 114.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_315682_2 1175654.A0A0S0NDG6_9CAUD 8.45e-80 252.0 4QDKA@10239|Viruses,4QUPP@35237|dsDNA viruses no RNA stage,4QPPG@28883|Caudovirales,4QMZH@10699|Siphoviridae 10699|Siphoviridae S nuclease activity - - - - - - - - - - - - - k59_48818_1 1096546.WYO_0164 1.78e-53 191.0 COG0749@1|root,COG0749@2|Bacteria,1MWX7@1224|Proteobacteria 1224|Proteobacteria L COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A,DNA_pol_A_exo1 k59_562516_1 1234888.K0A2J2_9VIRU 2.91e-76 247.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_297026_2 691965.D4P7C0_9CAUD 4.83e-59 186.0 4QDUR@10239|Viruses,4QVMY@35237|dsDNA viruses no RNA stage,4QU8R@28883|Caudovirales,4QKNQ@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_297026_3 742733.HMPREF9469_05035 1.41e-32 119.0 2DHA9@1|root,32U8X@2|Bacteria,1VD44@1239|Firmicutes,24NC3@186801|Clostridia,222SC@1506553|Lachnoclostridium 186801|Clostridia S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - - k59_49140_1 1500301.JQMF01000006_gene1766 9.86e-21 89.4 2E0FP@1|root,300A6@2|Bacteria,1PQHQ@1224|Proteobacteria,2V2WQ@28211|Alphaproteobacteria,4BJS5@82115|Rhizobiaceae 28211|Alphaproteobacteria L Phage endonuclease I - - - - - - - - - - - - Phage_endo_I k59_484806_2 145579.CAPSD_BPPHM 1.56e-191 553.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_484806_4 105154.Q9MBU0_9VIRU 7.5e-46 166.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_583732_2 1618259.A0A0C5I2B5_9CIRC 1.09e-46 166.0 4QE84@10239|Viruses,4QUKR@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_29795_1 89187.ISM_05190 5.49e-18 89.4 COG5281@1|root,COG5281@2|Bacteria,1R47M@1224|Proteobacteria,2TUIV@28211|Alphaproteobacteria,46QA2@74030|Roseovarius 28211|Alphaproteobacteria S COG5281 Phage-related minor tail protein - - - - - - - - - - - - - k59_649018_1 411465.PEPMIC_01335 2.79e-07 54.3 COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,248YB@186801|Clostridia,22GBR@1570339|Peptoniphilaceae 186801|Clostridia L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity polC - 2.7.7.7 ko:K02342,ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon k59_316158_1 795666.MW7_1575 1.3e-26 108.0 COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,2VJD3@28216|Betaproteobacteria,1JZZT@119060|Burkholderiaceae 28216|Betaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_3,Phage_integrase k59_625484_1 322855.Q52PN7_9CAUD 5.9e-26 111.0 4QBNE@10239|Viruses,4QXM4@35237|dsDNA viruses no RNA stage,4QPE9@28883|Caudovirales 28883|Caudovirales S Pfam:Carbam_trans_C - - - - - - - - - - - - - k59_525279_1 1556290.A0A0A0RQH0_9CAUD 0.00016 51.2 4QAK6@10239|Viruses,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_152913_9 36809.MAB_1759 1.44e-11 63.5 2BKJ5@1|root,32F0D@2|Bacteria,2HYIA@201174|Actinobacteria,23EHR@1762|Mycobacteriaceae 201174|Actinobacteria S Domain of unknown function (DUF4326) - - - - - - - - - - - - DUF4326 k59_49159_3 1636182.A0A0F6R505_9CAUD 3.62e-09 57.4 4QF35@10239|Viruses,4QPS1@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_234506_1 349161.Dred_1193 1.81e-91 282.0 COG0863@1|root,COG0863@2|Bacteria,1UZIN@1239|Firmicutes,24CGS@186801|Clostridia 186801|Clostridia L Belongs to the N(4) N(6)-methyltransferase family - - - - - - - - - - - - N6_N4_Mtase k59_234506_2 1121100.JCM6294_535 1.54e-98 313.0 COG0553@1|root,COG0863@1|root,COG0553@2|Bacteria,COG0863@2|Bacteria,4NHHF@976|Bacteroidetes,2FRI5@200643|Bacteroidia,4ATW7@815|Bacteroidaceae 976|Bacteroidetes KL DNA methylase - - - - - - - - - - - - Helicase_C,N6_N4_Mtase,SNF2_N k59_525303_2 1223545.GS4_41_00410 4.25e-24 99.4 2EGA5@1|root,33A1Y@2|Bacteria,2GSDD@201174|Actinobacteria 201174|Actinobacteria S HNH endonuclease - - - - - - - - - - - - HNH_3 k59_14614_1 691965.D4P7D6_9CAUD 3.06e-105 331.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_14614_2 428125.CLOLEP_01413 4.76e-34 120.0 2E2Y0@1|root,32XYV@2|Bacteria,1VD9S@1239|Firmicutes,24PK0@186801|Clostridia,3WPDR@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_551445_1 765911.Thivi_3542 6.25e-06 55.1 COG0741@1|root,COG3941@1|root,COG0741@2|Bacteria,COG3941@2|Bacteria,1MZWI@1224|Proteobacteria,1S51D@1236|Gammaproteobacteria 1236|Gammaproteobacteria D Mu-like prophage protein - - - - - - - - - - - - - k59_33701_1 1121887.AUDK01000017_gene82 2.18e-33 120.0 COG0338@1|root,COG0338@2|Bacteria 2|Bacteria L D12 class N6 adenine-specific DNA methyltransferase dmnB - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - Dam,MethyltransfD12 k59_424025_2 10704.B4UTP0_BP163 3.31e-13 73.2 4QBV3@10239|Viruses,4QW0W@35237|dsDNA viruses no RNA stage,4QPPJ@28883|Caudovirales,4QKW5@10699|Siphoviridae 10699|Siphoviridae S Phage Terminase - - - - - - - - - - - - - k59_448111_1 1788438.A0A190WHE1_9CIRC 1.63e-16 83.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_466272_1 1166130.H650_15670 8.69e-23 94.4 COG3108@1|root,COG3108@2|Bacteria,1RICX@1224|Proteobacteria,1S6D5@1236|Gammaproteobacteria 1236|Gammaproteobacteria S peptidase M15 - - - ko:K17733 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M15_4 k59_629771_3 1540823.A0A088FC23_9CAUD 1.26e-19 94.7 4QC5D@10239|Viruses,4QPVU@28883|Caudovirales,4QM4F@10699|Siphoviridae 10699|Siphoviridae S Protein of unknown function (DUF2800) - - - - - - - - - - - - - k59_490687_1 1196095.GAPWK_0054 8.35e-28 124.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria 1236|Gammaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_629786_1 1692249.A0A0K1RLN8_9CIRC 3.29e-13 68.9 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_383260_1 1408428.JNJP01000005_gene5 2.55e-12 68.9 2C9JF@1|root,32RPD@2|Bacteria,1N8CG@1224|Proteobacteria,42REW@68525|delta/epsilon subdivisions,2WNQ1@28221|Deltaproteobacteria,2MB30@213115|Desulfovibrionales 28221|Deltaproteobacteria S ERF superfamily - - - - - - - - - - - - ERF k59_466290_2 938709.AUSH02000001_gene1577 1.19e-05 51.2 COG1361@1|root,COG2911@1|root,COG4886@1|root,COG1361@2|Bacteria,COG2911@2|Bacteria,COG4886@2|Bacteria,4NJQ1@976|Bacteroidetes 976|Bacteroidetes O Protein conserved in bacteria - - - - - - - - - - - - Big_2,CHU_C,Laminin_G_3 k59_52132_1 1121447.JONL01000012_gene3405 5.79e-30 123.0 COG0503@1|root,COG2518@1|root,COG0503@2|Bacteria,COG2518@2|Bacteria 2|Bacteria O Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins apt - 2.1.1.163,2.1.1.201,2.1.1.77,2.4.2.7 ko:K00573,ko:K00759,ko:K03183,ko:K07003 ko00130,ko00230,ko01100,ko01110,map00130,map00230,map01100,map01110 M00116,M00117 R00190,R01229,R04378,R04990,R04993,R06859,R08774,R09736 RC00003,RC00063,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000,ko04147 - - - DUF3560,Methyltransf_21,Pribosyltran k59_424430_2 477184.KYC_12548 1.11e-71 224.0 28JXH@1|root,2Z9MZ@2|Bacteria,1MXNC@1224|Proteobacteria 1224|Proteobacteria S RecT family STY2074 - - - - - - - - - - - RecT k59_655687_1 388051.AUFE01000035_gene4020 1.19e-59 200.0 COG4653@1|root,COG4653@2|Bacteria 2|Bacteria G Phage capsid family - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_142508_1 1504672.669782891 4.01e-17 82.8 COG2931@1|root,COG2931@2|Bacteria,1R7DP@1224|Proteobacteria 1224|Proteobacteria Q Collagen triple helix repeat - - - - - - - - - - - - Collagen k59_363600_1 682795.AciX8_1835 7.32e-52 190.0 COG4626@1|root,COG4626@2|Bacteria,3Y7XC@57723|Acidobacteria,2JMX4@204432|Acidobacteriia 204432|Acidobacteriia S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_324994_1 417280.A1YZY2_9CAUD 3.73e-38 146.0 4QCZC@10239|Viruses,4QX3V@35237|dsDNA viruses no RNA stage,4QRH3@28883|Caudovirales,4QHVR@10662|Myoviridae 10662|Myoviridae S Bacterial DNA polymerase III alpha subunit - - - - - - - - - - - - - k59_242186_2 1408428.JNJP01000003_gene3493 1.82e-73 228.0 COG0270@1|root,COG0270@2|Bacteria 2|Bacteria L DNA (cytosine-5-)-methyltransferase activity - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_242186_3 1147139.A0A0A6Z582_9CAUD 1.12e-08 59.3 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales,4QNBQ@10744|Podoviridae 10744|Podoviridae S HNH endonuclease - - - - - - - - - - - - - k59_570785_1 212035.TOP2_MIMIV 1.23e-39 164.0 4QDCP@10239|Viruses,4QVJZ@35237|dsDNA viruses no RNA stage 10239|Viruses S DNA gyrase B - GO:0005575,GO:0032991 - - - - - - - - - - - k59_19053_1 1986029.Q9MBM6_9VIRU 9.61e-22 92.4 4QDBB@10239|Viruses,4QUM0@29258|ssDNA viruses,4QP4D@10841|Microviridae 10841|Microviridae S Chlamydia-phage Chp2 scaffold (Chlamy_scaf) - - - - - - - - - - - - - k59_470760_1 5762.XP_002674895.1 7.77e-05 50.1 28IEN@1|root,2QQRD@2759|Eukaryota 2759|Eukaryota S Poly A polymerase regulatory subunit - - 2.1.1.296 ko:K18776,ko:K18777 - - R10812 RC00003,RC00466 ko00000,ko01000,ko03019 - - - PARP_regulatory k59_325031_2 424716.B1GS49_9CAUD 3.13e-06 49.3 4QHQR@10239|Viruses,4QV7H@35237|dsDNA viruses no RNA stage,4QSV7@28883|Caudovirales,4QKSI@10699|Siphoviridae 10699|Siphoviridae S DNA binding - - - - - - - - - - - - - k59_305559_1 1094553.MCS_01290 4.35e-07 58.2 COG4675@1|root,COG4675@2|Bacteria,1N0FZ@1224|Proteobacteria,2UDXB@28211|Alphaproteobacteria,48T3C@772|Bartonellaceae 28211|Alphaproteobacteria S Phage Tail Collar Domain - - - - - - - - - - - - Collar k59_364145_1 1249480.B649_06870 2.58e-07 58.5 COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,42VWM@68525|delta/epsilon subdivisions,2YQKK@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria S COG0714 MoxR-like - - - - - - - - - - - - AAA_5 k59_117606_2 1692249.A0A0K1RL40_9CIRC 3.34e-59 196.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_571357_1 575540.Isop_2452 4.64e-28 116.0 COG5525@1|root,COG5525@2|Bacteria,2IXN3@203682|Planctomycetes 203682|Planctomycetes S Phage terminase large subunit (GpA) - - - - - - - - - - - - Terminase_GpA k59_388804_1 1541065.JRFE01000019_gene3243 1.53e-21 103.0 COG0642@1|root,COG2202@1|root,COG2203@1|root,COG4191@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria,1FZYQ@1117|Cyanobacteria,3VI2D@52604|Pleurocapsales 1117|Cyanobacteria T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - - - - - - - - - - CBS,GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg k59_284279_1 1125863.JAFN01000001_gene3562 4.89e-18 90.1 COG4733@1|root,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria,42QDD@68525|delta/epsilon subdivisions,2WIU9@28221|Deltaproteobacteria 28221|Deltaproteobacteria U Phage-related protein, tail - - - - - - - - - - - - Phage-tail_3 k59_429451_1 46681.XP_001735097.1 5.1e-07 58.2 COG5049@1|root,KOG2044@2759|Eukaryota,3XF9X@554915|Amoebozoa 554915|Amoebozoa AL XRN 5'-3' exonuclease N-terminus - - - ko:K12619 ko03008,ko03018,map03008,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03016,ko03019,ko03021 - - - XRN_N k59_305605_2 1041826.FCOL_05440 6.3e-106 310.0 COG0270@1|root,COG0270@2|Bacteria,4P351@976|Bacteroidetes,1I9UJ@117743|Flavobacteriia,2NZ0G@237|Flavobacterium 976|Bacteroidetes L C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_143098_1 713587.THITH_01545 2.33e-85 272.0 COG3378@1|root,COG3378@2|Bacteria,1QN90@1224|Proteobacteria,1SH5I@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage plasmid primase P4 family - - - - - - - - - - - - PriCT_2,Prim-Pol k59_19687_2 645099.MREP_BBTVA 1.12e-10 68.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_471354_1 1120792.JAFV01000001_gene3539 2.1e-27 116.0 COG4695@1|root,COG4695@2|Bacteria,1MUP5@1224|Proteobacteria,2TT33@28211|Alphaproteobacteria,36ZVJ@31993|Methylocystaceae 28211|Alphaproteobacteria S Phage portal protein - - - - - - - - - - - - Phage_portal k59_247490_1 1120980.JQKH01000096_gene845 0.000734 45.4 COG3298@1|root,COG3298@2|Bacteria,1MVZJ@1224|Proteobacteria,2VISP@28216|Betaproteobacteria,2KQ37@206351|Neisseriales 206351|Neisseriales L Psort location Cytoplasmic, score 8.96 - - - ko:K07501 - - - - ko00000 - - - DNA_pol_B_exo2 k59_493300_1 1238190.AMQY01000010_gene2305 1.74e-44 162.0 COG5377@1|root,COG5377@2|Bacteria,1MWP8@1224|Proteobacteria,1RN9Q@1236|Gammaproteobacteria,1XN9D@135619|Oceanospirillales 135619|Oceanospirillales L COG5377 Phage-related protein - - - - - - - - - - - - YqaJ k59_493300_2 287.DR97_5374 1.87e-99 299.0 COG3723@1|root,COG3723@2|Bacteria,1R6DB@1224|Proteobacteria,1RZZ3@1236|Gammaproteobacteria,1YKA6@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria L RecT family recT GO:0000724,GO:0000725,GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0018130,GO:0019438,GO:0032392,GO:0032508,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043150,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071704,GO:0071840,GO:0071897,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - ko:K07455 - - - - ko00000,ko03400 - - - RecT k59_83270_2 237368.SCABRO_03334 2.29e-10 60.5 COG1327@1|root,COG1327@2|Bacteria,2IZQ3@203682|Planctomycetes 203682|Planctomycetes K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes nrdR - - ko:K07738 - - - - ko00000,ko03000 - - - ATP-cone k59_370043_1 118161.KB235917_gene94 2.59e-15 82.4 COG5545@1|root,COG5545@2|Bacteria,1G1ZC@1117|Cyanobacteria,3VMRW@52604|Pleurocapsales 1117|Cyanobacteria S Virulence-associated protein E - - - - - - - - - - - - DUF3854,VirE k59_164966_2 1609634.A0A0C5ANA6_9VIRU 1.26e-11 68.9 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_123920_1 749222.Nitsa_0068 2.82e-21 99.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2YN94@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdA - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN k59_637010_2 566461.SSFG_00959 2.03e-12 65.1 2CC1Y@1|root,32RUK@2|Bacteria,2IQ4Q@201174|Actinobacteria 201174|Actinobacteria K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA whmD - - ko:K18955 - - - - ko00000,ko03000 - - - Whib k59_247511_1 1379717.S5SY19_9CIRC 6.08e-65 211.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_308725_2 1692244.A0A0K1RLR5_9CIRC 3.89e-54 179.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_595990_1 861299.J421_4323 7.13e-17 89.7 COG4643@1|root,COG4643@2|Bacteria 2|Bacteria P DNA integration - - - ko:K06919 - - - - ko00000 - - - DUF3631,Toprim_3 k59_349922_1 1336208.JADY01000006_gene611 2.53e-17 89.4 COG4695@1|root,COG4695@2|Bacteria,1MUP5@1224|Proteobacteria,2TT33@28211|Alphaproteobacteria 28211|Alphaproteobacteria S portal protein - - - - - - - - - - - - Phage_portal k59_473415_1 999541.bgla_1g10970 1.02e-20 101.0 COG4733@1|root,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria,2VJEP@28216|Betaproteobacteria,1KBVU@119060|Burkholderiaceae 28216|Betaproteobacteria S Phage-related protein, tail - - - - - - - - - - - - DUF1983,Phage-tail_3 k59_597874_2 580340.Tlie_0724 2.24e-29 111.0 COG0756@1|root,COG0756@2|Bacteria,3TB7M@508458|Synergistetes 508458|Synergistetes F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA dut - 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase k59_455038_1 864069.MicloDRAFT_00070230 1.21e-20 90.9 COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,2V9NK@28211|Alphaproteobacteria,1JYU9@119045|Methylobacteriaceae 28211|Alphaproteobacteria H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds - - 4.3.99.3 ko:K10026 ko00790,ko01100,map00790,map01100 - R10002 RC02989 ko00000,ko00001,ko01000,ko03016 - - - Fer4_14 k59_577545_2 1347342.BN863_1500 9.73e-25 99.4 COG2131@1|root,COG2131@2|Bacteria,4NM48@976|Bacteroidetes,1I1AE@117743|Flavobacteriia 976|Bacteroidetes F deaminase comEB - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 k59_577545_3 285514.JNWO01000071_gene4 5.82e-17 83.6 COG0749@1|root,COG0749@2|Bacteria,2IG0A@201174|Actinobacteria 201174|Actinobacteria L DNA polymerase - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_332126_1 1234880.K0A2H8_9CIRC 4.71e-29 119.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_85931_2 767434.Fraau_1253 3.39e-27 105.0 COG2131@1|root,COG2131@2|Bacteria,1NC75@1224|Proteobacteria,1T01U@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Deoxycytidylate deaminase - - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 k59_597886_1 1540097.A0A0A0YRN0_9CAUD 8.1e-131 397.0 4QF3C@10239|Viruses,4QU4U@28883|Caudovirales,4QNNQ@10744|Podoviridae 10744|Podoviridae S host cell wall - - - - - - - - - - - - - k59_290790_1 1788454.A0A190WHE4_9CIRC 1.61e-28 112.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_413797_1 1357279.N018_05425 5.58e-30 122.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,1SMCU@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_332539_1 1530186.JQEY01000002_gene1537 6.97e-68 229.0 COG1061@1|root,COG1061@2|Bacteria,1MV9F@1224|Proteobacteria,2TUXC@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Type III restriction enzyme res subunit - - - ko:K19789 - - - - ko00000,ko03400 - - - DUF3427,HIT,Helicase_C,PLDc_2,ResIII,UPF0547 k59_23986_2 1618260.A0A0C5I2C5_9CIRC 6.07e-84 259.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_372649_1 1385658.U5KPZ6_9VIRU 1.43e-184 536.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_250253_2 696281.Desru_3571 4.54e-08 55.1 29X0R@1|root,30IP0@2|Bacteria,1V3X0@1239|Firmicutes 1239|Firmicutes L NUMOD4 domain protein - - - - - - - - - - - - HNH_3,NUMOD4 k59_105356_1 1475143.W8SNN0_9CIRC 1.2e-28 117.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_517182_1 1042876.PPS_1220 7.43e-39 142.0 COG0582@1|root,COG0582@2|Bacteria,1QB64@1224|Proteobacteria,1RY8S@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_1,Phage_int_SAM_4,Phage_integrase k59_270171_1 1051675.G0YQF1_9CAUD 1.43e-28 117.0 4QW35@35237|dsDNA viruses no RNA stage,4QQ4Q@28883|Caudovirales,4QNNN@10744|Podoviridae 10744|Podoviridae S UvrD-like helicase C-terminal domain - - - - - - - - - - - - - k59_191539_1 457398.HMPREF0326_02660 4.4e-22 97.8 COG4227@1|root,COG4643@1|root,COG4227@2|Bacteria,COG4643@2|Bacteria,1MU8I@1224|Proteobacteria,42N43@68525|delta/epsilon subdivisions,2WM7N@28221|Deltaproteobacteria,2M823@213115|Desulfovibrionales 28221|Deltaproteobacteria L Domain of unknown function (DUF1738) - - - - - - - - - - - - DUF1738,Toprim_3 k59_231666_1 1127692.HMPREF9075_02379 2.83e-18 84.0 COG0270@1|root,COG0270@2|Bacteria,4NVMZ@976|Bacteroidetes,1IEAJ@117743|Flavobacteriia,1EQWM@1016|Capnocytophaga 976|Bacteroidetes L C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_231666_3 1121100.JCM6294_1074 2.04e-49 171.0 COG0270@1|root,COG0270@2|Bacteria,4P3IR@976|Bacteroidetes,2FN10@200643|Bacteroidia,4AN47@815|Bacteroidaceae 976|Bacteroidetes H C-5 cytosine-specific DNA methylase - - - - - - - - - - - - DNA_methylase k59_541758_1 1234888.K0A2J2_9VIRU 5.09e-63 211.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_107757_1 264462.Bd1130 3.7e-11 69.3 COG3209@1|root,COG3209@2|Bacteria,1QY1R@1224|Proteobacteria,43C93@68525|delta/epsilon subdivisions,2MUT2@213481|Bdellovibrionales,2X7JI@28221|Deltaproteobacteria 213481|Bdellovibrionales M cell wall surface anchor family protein - - - - - - - - - - - - Peptidase_S74 k59_253463_3 105154.Q9MBU6_9VIRU 9.56e-187 541.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_253463_6 1609634.A0A0C5AFT2_9VIRU 1.38e-27 116.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_580916_1 1408419.JHYG01000005_gene577 2.6e-39 144.0 COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,2TS2G@28211|Alphaproteobacteria,2JQ5C@204441|Rhodospirillales 204441|Rhodospirillales L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_3,Phage_integrase k59_376494_1 120574.Q94M55_9CAUD 9.92e-06 47.4 4QV7S@35237|dsDNA viruses no RNA stage,4QPCP@28883|Caudovirales,4QKP2@10699|Siphoviridae 10699|Siphoviridae S YopX protein - - - - - - - - - - - - - k59_110372_1 1266908.AQPB01000049_gene779 9.16e-40 149.0 COG4643@1|root,COG4643@2|Bacteria,1R6M4@1224|Proteobacteria 1224|Proteobacteria L Phage plasmid primase P4 family - - - ko:K06919 - - - - ko00000 - - - PriCT_2,Prim-Pol k59_235688_1 478749.BRYFOR_08571 1.33e-17 86.7 2A0KC@1|root,31HXF@2|Bacteria,1V8F6@1239|Firmicutes,24K13@186801|Clostridia 186801|Clostridia S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - - k59_235688_5 691965.D4P7H8_9CAUD 1.27e-52 176.0 4QG1E@10239|Viruses,4QZE1@35237|dsDNA viruses no RNA stage,4QU6Q@28883|Caudovirales,4QMKH@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_235688_6 478749.BRYFOR_08565 1.29e-65 215.0 2A0KC@1|root,2ZGJK@2|Bacteria,1V2JS@1239|Firmicutes,24H6R@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_235688_9 691965.D4P7I3_9CAUD 0.0 1494.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_235688_10 691965.D4P7I8_9CAUD 3.16e-46 156.0 4QGJH@10239|Viruses,4QZ35@35237|dsDNA viruses no RNA stage,4QRZS@28883|Caudovirales,4QMAA@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_380306_1 345201.VF244_IIV3 1.16e-25 107.0 4QAIK@10239|Viruses,4QUPH@35237|dsDNA viruses no RNA stage 10239|Viruses S bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity - - - - - - - - - - - - - k59_400252_1 279383.Q5DN23_9CAUD 7.32e-12 78.2 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_134929_1 356851.JOAN01000015_gene2749 5.98e-08 58.5 COG1404@1|root,COG3055@1|root,COG1404@2|Bacteria,COG3055@2|Bacteria,2HU5X@201174|Actinobacteria,4DBT0@85008|Micromonosporales 2|Bacteria O Peptidase S8 and S53 subtilisin kexin sedolisin nanM GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0005623,GO:0016853,GO:0016854,GO:0016857,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 5.1.3.24 ko:K13276,ko:K17948 - - - - ko00000,ko01000,ko01002,ko03110 - - - CarbopepD_reg_2,CarboxypepD_reg,Inhibitor_I9,Kelch_1,Kelch_4,Kelch_6,PKD,Peptidase_M6,Peptidase_S8 k59_96010_1 1476390.A0A060RJ50_9CAUD 9.51e-40 156.0 4QBSJ@10239|Viruses,4QXH4@35237|dsDNA viruses no RNA stage,4QPFJ@28883|Caudovirales,4QKUK@10699|Siphoviridae 10699|Siphoviridae S DNA primase activity - - - - - - - - - - - - - k59_342216_2 278963.ATWD01000001_gene2337 1.96e-34 123.0 2AV7S@1|root,31KYE@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_50029_1 344747.PM8797T_26995 1.17e-82 283.0 COG3087@1|root,COG3087@2|Bacteria,2IX3F@203682|Planctomycetes 203682|Planctomycetes D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - - - - - - - - - - - k59_357863_1 459349.CLOAM1507 1.97e-12 68.2 COG0863@1|root,COG0863@2|Bacteria 2|Bacteria L N-4 methylation of cytosine - - 2.1.1.113,2.1.1.72 ko:K00571,ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_585584_4 1468411.X2L008_9CAUD 2.76e-17 80.9 4QFED@10239|Viruses,4R072@35237|dsDNA viruses no RNA stage,4QPEH@28883|Caudovirales,4QN2V@10699|Siphoviridae 10699|Siphoviridae S tRNA modification - - - - - - - - - - - - - k59_548171_1 1051675.G0YQF5_9CAUD 2.21e-29 123.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_527843_2 953739.SVEN_2147 9.61e-18 82.8 2EGA5@1|root,33A1Y@2|Bacteria,2GSDD@201174|Actinobacteria 201174|Actinobacteria S HNH endonuclease - - - - - - - - - - - - HNH_3 k59_552620_1 941824.TCEL_01744 1.33e-35 137.0 COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,248IA@186801|Clostridia,36E84@31979|Clostridiaceae 186801|Clostridia M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG - 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 - Glyco_tran_28_C,Glyco_transf_28 k59_532328_1 1609634.A0A0C5AFV4_9VIRU 2.57e-57 198.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_655804_1 1379719.S5TMX6_9CIRC 4.44e-47 165.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_280410_1 641526.ADIWIN_1986 2.93e-14 83.2 COG5295@1|root,COG5295@2|Bacteria,4NJTK@976|Bacteroidetes,1HZNB@117743|Flavobacteriia 976|Bacteroidetes UW surface antigen - - - - - - - - - - - - Peptidase_S74 k59_449162_1 1227266.HMPREF1551_00524 3.48e-26 110.0 COG1783@1|root,COG1783@2|Bacteria,4NHPB@976|Bacteroidetes,1IH79@117743|Flavobacteriia,1ESIH@1016|Capnocytophaga 976|Bacteroidetes S Phage terminase, large subunit, PBSX family - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C k59_655880_1 1692253.A0A0K1RLM4_9CIRC 7.83e-18 90.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_567786_1 765420.OSCT_3100 0.000141 45.8 COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,2G854@200795|Chloroflexi 200795|Chloroflexi M Domain of unknown function DUF11 - - - - - - - - - - - - DUF11 k59_15932_1 388051.AUFE01000035_gene4020 1.54e-36 139.0 COG4653@1|root,COG4653@2|Bacteria 2|Bacteria G Phage capsid family - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_347137_1 1173762.S4TRQ3_9CAUD 6.79e-19 91.7 4QBY0@10239|Viruses,4QW35@35237|dsDNA viruses no RNA stage,4QQ4Q@28883|Caudovirales,4QNNN@10744|Podoviridae 10744|Podoviridae S UvrD-like helicase C-terminal domain - - - - - - - - - - - - - k59_280787_1 1423144.Gal_04433 0.000291 51.6 COG4733@1|root,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria,2TV2W@28211|Alphaproteobacteria 28211|Alphaproteobacteria S COG4733 Phage-related protein, tail component - - - - - - - - - - - - Phage-tail_3 k59_157491_1 1165094.RINTHH_3920 8.16e-55 184.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_449671_1 691965.D4P7L7_9CAUD 1e-30 125.0 4QB9J@10239|Viruses,4QXFE@35237|dsDNA viruses no RNA stage,4QS1Z@28883|Caudovirales,4QN8F@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_368762_24 1499684.CCNP01000018_gene1741 3.89e-07 60.1 COG3409@1|root,COG3409@2|Bacteria,1TS29@1239|Firmicutes,247SQ@186801|Clostridia,36UHG@31979|Clostridiaceae 186801|Clostridia M Peptidoglycan-binding domain 1 protein - - - - - - - - - - - - LysM,PG_binding_1,SpoIID k59_368762_28 1176422.I6R9Y1_9CAUD 2.32e-26 112.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_368762_32 443254.Marpi_0320 3.71e-19 98.2 COG1783@1|root,COG1783@2|Bacteria,2GE2Z@200918|Thermotogae 200918|Thermotogae S Terminase RNAseH like domain - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C k59_368762_43 585543.HMPREF0969_03348 1.73e-11 63.9 2E2D8@1|root,32XI3@2|Bacteria,4NS7Z@976|Bacteroidetes,2FTX3@200643|Bacteroidia,4ARPA@815|Bacteroidaceae 976|Bacteroidetes S WYL_2, Sm-like SH3 beta-barrel fold - - - - - - - - - - - - WYL_2 k59_368762_44 1408428.JNJP01000079_gene3367 6.84e-87 283.0 COG0827@1|root,COG0827@2|Bacteria,1N9G8@1224|Proteobacteria,42YEM@68525|delta/epsilon subdivisions,2WTY5@28221|Deltaproteobacteria,2ME31@213115|Desulfovibrionales 28221|Deltaproteobacteria L Domain of unknown function (DUF4942) - - - - - - - - - - - - DUF4942 k59_368762_55 497965.Cyan7822_3833 2.18e-54 204.0 COG0210@1|root,COG0210@2|Bacteria,1GQP4@1117|Cyanobacteria 1117|Cyanobacteria L PFAM UvrD REP helicase - - - - - - - - - - - - UvrD-helicase,UvrD_C k59_368762_76 1121286.AUMT01000013_gene2646 3.41e-12 80.5 COG5283@1|root,COG5283@2|Bacteria,4NG54@976|Bacteroidetes,1I01C@117743|Flavobacteriia,3ZTVT@59732|Chryseobacterium 976|Bacteroidetes D Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_368762_78 1005058.UMN179_00178 3.82e-14 84.0 COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,1RNYW@1236|Gammaproteobacteria,1Y748@135625|Pasteurellales 135625|Pasteurellales OU signal peptide peptidase sppA - - ko:K04773 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49 k59_122523_2 439235.Dalk_4426 2.94e-26 102.0 arCOG05626@1|root,32V4D@2|Bacteria,1NXWW@1224|Proteobacteria,430Y7@68525|delta/epsilon subdivisions,2WVX7@28221|Deltaproteobacteria 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_60732_1 1111131.HMPREF1255_0618 1.45e-50 184.0 COG1061@1|root,COG1061@2|Bacteria,2GIU5@201174|Actinobacteria,4DP3W@85009|Propionibacteriales 201174|Actinobacteria L Type III restriction enzyme, res subunit sdrA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - ResIII k59_122630_2 1051675.G0YQH8_9CAUD 1.19e-08 61.2 4QEQT@10239|Viruses,4QYJH@35237|dsDNA viruses no RNA stage,4QQ1B@28883|Caudovirales,4QNPW@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_225144_2 1692252.A0A0K1RL35_9CIRC 2.08e-42 151.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_60751_2 1177928.TH2_05948 9.18e-07 51.2 COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,2U05W@28211|Alphaproteobacteria,2JS7J@204441|Rhodospirillales 204441|Rhodospirillales L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_3,Phage_integrase k59_187016_2 1692255.A0A0K1RL52_9CIRC 2.1e-92 284.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_453821_6 1548903.A0A0A1IWR6_9CAUD 3.13e-11 65.5 4QB7P@10239|Viruses,4QPMV@28883|Caudovirales 28883|Caudovirales S metallopeptidase activity - - - - - - - - - - - - - k59_248801_1 1618238.A0A0C5IB41_9CIRC 0.000416 43.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_494530_2 756275.H2BCT9_9CAUD 2.16e-09 69.7 4QEXP@10239|Viruses,4QUDQ@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_474584_2 979533.F1D0U3_9CAUD 5.77e-06 48.5 4QAM4@10239|Viruses,4QWEA@35237|dsDNA viruses no RNA stage,4QPGM@28883|Caudovirales,4QNJD@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_474584_8 1166018.FAES_4045 2.2e-35 133.0 COG1896@1|root,COG1896@2|Bacteria,4NUQR@976|Bacteroidetes,47W5J@768503|Cytophagia 976|Bacteroidetes S Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates - - - ko:K06952 - - - - ko00000 - - - - k59_597316_3 1173762.S4TRR3_9CAUD 1.77e-42 151.0 4QD9V@10239|Viruses,4QYQ1@35237|dsDNA viruses no RNA stage,4QTHS@28883|Caudovirales,4QP1H@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_475186_1 320850.Q4ZA78_9CAUD 1.51e-24 100.0 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales,4QKM7@10699|Siphoviridae 10699|Siphoviridae S HNH endonuclease - - - - - - - - - - - - - k59_539767_10 290402.Cbei_1632 5.28e-15 84.7 COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,1TPHP@1239|Firmicutes,249MR@186801|Clostridia,36FKT@31979|Clostridiaceae 186801|Clostridia KL Belongs to the N(4) N(6)-methyltransferase family - - - - - - - - - - - - N6_N4_Mtase,ParBc k59_539767_15 1123508.JH636439_gene1949 1.23e-07 62.8 2DM4Q@1|root,31Q2U@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_457636_1 753085.F4YCR7_9CAUD 8.87e-18 92.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_209537_1 1192868.CAIU01000008_gene966 3.05e-55 181.0 2A4D4@1|root,30SYX@2|Bacteria,1PCIM@1224|Proteobacteria,2USSQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_94851_1 1214065.BAGV01000099_gene2076 1.17e-68 220.0 COG3969@1|root,COG3969@2|Bacteria,1NBDM@1224|Proteobacteria,1RYRP@1236|Gammaproteobacteria 1236|Gammaproteobacteria S phosphoadenosine phosphosulfate ybdN - - - - - - - - - - - DUF3440,PAPS_reduct k59_626108_2 1219045.BV98_000743 1.41e-25 104.0 COG4096@1|root,COG4096@2|Bacteria,1QXJA@1224|Proteobacteria,2TXZ6@28211|Alphaproteobacteria 28211|Alphaproteobacteria V Type III restriction enzyme, res subunit - - 3.1.21.5 ko:K01156 - - - - ko00000,ko01000,ko02048 - - - ResIII k59_134062_2 1385658.U5KQQ9_9VIRU 1.71e-24 103.0 4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_626110_2 266265.Bxe_A3100 4.91e-18 86.3 2DM17@1|root,319VU@2|Bacteria,1R6RI@1224|Proteobacteria,2WG8E@28216|Betaproteobacteria,1KIBI@119060|Burkholderiaceae 28216|Betaproteobacteria L PFAM GIY-YIG catalytic domain - - - - - - - - - - - - - k59_297618_10 1487953.JMKF01000022_gene2495 7.39e-36 137.0 COG3108@1|root,COG3772@1|root,COG3108@2|Bacteria,COG3772@2|Bacteria,1G7YF@1117|Cyanobacteria,1HASB@1150|Oscillatoriales 1117|Cyanobacteria M Phage lysozyme - - - - - - - - - - - - PG_binding_1,Phage_lysozyme k59_502225_2 1121445.ATUZ01000003_gene36 3.3e-38 145.0 COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,42QA8@68525|delta/epsilon subdivisions,2WJBW@28221|Deltaproteobacteria,2M8NS@213115|Desulfovibrionales 28221|Deltaproteobacteria S PFAM ATPase associated with various cellular activities - - - - - - - - - - - - AAA_3,AAA_5 k59_546398_1 929562.Emtol_1428 9.4e-05 48.5 COG1403@1|root,COG1403@2|Bacteria,4NJ0T@976|Bacteroidetes,47MEF@768503|Cytophagia 976|Bacteroidetes L HNH endonuclease - - - - - - - - - - - - HNH,HNH_5 k59_109909_2 866895.HBHAL_2436 1.32e-09 63.9 COG0438@1|root,COG2520@1|root,COG0438@2|Bacteria,COG2520@2|Bacteria,1U9Z2@1239|Firmicutes,4HEVV@91061|Bacilli 91061|Bacilli M Glycosyl transferases group 1 - - - - - - - - - - - - Glycos_transf_1,Glycos_transf_2,Methyltransf_21 k59_526165_1 1327982.R9ZZE9_9CAUD 5.2e-183 526.0 4QGM3@10239|Viruses,4QYG4@35237|dsDNA viruses no RNA stage,4QPTC@28883|Caudovirales,4QMVS@10699|Siphoviridae 10699|Siphoviridae S oxidoreductase activity - - - - - - - - - - - - - k59_526165_2 679189.HMPREF9019_0945 2.6e-14 71.6 2EHJD@1|root,33BB9@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - HTH_8 k59_153823_1 679937.Bcop_0420 5.63e-44 156.0 COG0530@1|root,COG0530@2|Bacteria,4NFBC@976|Bacteroidetes,2FNX9@200643|Bacteroidia,4ANFN@815|Bacteroidaceae 976|Bacteroidetes P K -dependent Na Ca exchanger yrbG - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex k59_584888_1 886293.Sinac_0178 2.44e-05 48.9 COG2189@1|root,COG2189@2|Bacteria,2IWRP@203682|Planctomycetes 203682|Planctomycetes L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_605215_1 1244869.H261_11074 6.76e-20 94.4 COG4733@1|root,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria,2TV2W@28211|Alphaproteobacteria,2JV2T@204441|Rhodospirillales 204441|Rhodospirillales S COG4733 Phage-related protein, tail component - - - - - - - - - - - - Lambda_tail_I,Phage-tail_3 k59_444158_1 1986029.Q9MBM6_9VIRU 7.61e-12 66.6 4QDBB@10239|Viruses,4QUM0@29258|ssDNA viruses,4QP4D@10841|Microviridae 10841|Microviridae S Chlamydia-phage Chp2 scaffold (Chlamy_scaf) - - - - - - - - - - - - - k59_444158_3 1986029.Q9MBM8_9VIRU 1.32e-13 70.1 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_257505_1 399795.CtesDRAFT_PD0612 6.98e-07 57.0 COG3209@1|root,COG3210@1|root,COG4675@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,COG4675@2|Bacteria,1RJRG@1224|Proteobacteria,2WEZQ@28216|Betaproteobacteria 28216|Betaproteobacteria M COG3209 Rhs family protein - - - - - - - - - - - - - k59_195325_1 1414742.V5R9A3_9CAUD 1.73e-13 70.5 4QD8P@10239|Viruses,4QZGQ@35237|dsDNA viruses no RNA stage,4QRTU@28883|Caudovirales,4QMS6@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_110232_2 194699.Q774Z7_BPBPP 4.63e-20 85.1 4QAZF@10239|Viruses,4QUTY@35237|dsDNA viruses no RNA stage,4QPH6@28883|Caudovirales,4QNEM@10744|Podoviridae 10744|Podoviridae S Protein of unknwon function (DUF3310) - - - - - - - - - - - - - k59_462813_1 1556290.A0A0A0RQE6_9CAUD 1.52e-26 104.0 4QAUS@10239|Viruses,4QQ2S@28883|Caudovirales,4QKRA@10699|Siphoviridae 10699|Siphoviridae S flavin adenine dinucleotide binding - - - - - - - - - - - - - k59_175984_1 1038860.AXAP01000015_gene2003 8.45e-37 143.0 COG3740@1|root,COG3740@2|Bacteria,1QVIJ@1224|Proteobacteria,2TVIM@28211|Alphaproteobacteria,3K0XM@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Caudovirus prohead serine protease - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_564192_1 887898.HMPREF0551_0616 7.82e-19 87.8 COG0546@1|root,COG0546@2|Bacteria,1RDA7@1224|Proteobacteria,2VIZ2@28216|Betaproteobacteria,1K0S7@119060|Burkholderiaceae 28216|Betaproteobacteria S HAD-superfamily hydrolase, subfamily IA, variant 1 ppaX - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 k59_298153_1 1476391.X5L4L4_9CAUD 1.28e-16 81.6 4QEWC@10239|Viruses,4QYMK@35237|dsDNA viruses no RNA stage,4QUH4@28883|Caudovirales,4QP0K@10744|Podoviridae 10744|Podoviridae S signal transduction - - - - - - - - - - - - - k59_526939_1 1353529.M899_2545 3.94e-14 78.6 2EGQU@1|root,33AGZ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Collagen k59_502776_1 1234888.K0A2J2_9VIRU 3.87e-61 207.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_587582_1 640513.Entas_3082 2.79e-85 270.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,1RP8Z@1236|Gammaproteobacteria,3X3FH@547|Enterobacter 1236|Gammaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_346025_1 1618260.A0A0C5I2C5_9CIRC 3.48e-16 78.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_179853_1 105154.Q9MBU6_9VIRU 4.58e-76 244.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_655480_2 929704.Myrod_0673 6.36e-22 88.6 2EPRJ@1|root,33HC2@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_403154_2 1121406.JAEX01000006_gene2231 1.07e-14 78.6 COG4974@1|root,COG4974@2|Bacteria,1QU6A@1224|Proteobacteria,42Q4U@68525|delta/epsilon subdivisions,2WJ08@28221|Deltaproteobacteria,2M93X@213115|Desulfovibrionales 28221|Deltaproteobacteria D Belongs to the 'phage' integrase family. XerC subfamily xerC - - ko:K03733,ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase k59_403154_3 641526.ADIWIN_2664 5.89e-83 254.0 2DM6V@1|root,31Z5X@2|Bacteria,4NR9U@976|Bacteroidetes,1I88Y@117743|Flavobacteriia 976|Bacteroidetes S D12 class N6 adenine-specific DNA methyltransferase - - - - - - - - - - - - MethyltransfD12 k59_100122_2 1306406.ASHX01000001_gene2679 2.57e-12 67.4 COG4912@1|root,COG4912@2|Bacteria,2ID3C@201174|Actinobacteria 201174|Actinobacteria L DNA alkylation repair - - - - - - - - - - - - DNA_alkylation k59_260912_1 240292.Ava_2569 5.02e-20 95.9 COG5545@1|root,COG5545@2|Bacteria,1G4RT@1117|Cyanobacteria,1HNNZ@1161|Nostocales 1117|Cyanobacteria S Virulence-associated protein E - - - - - - - - - - - - RepB_primase,VirE k59_179866_1 1123242.JH636435_gene2404 2.66e-20 97.1 COG5525@1|root,COG5525@2|Bacteria,2IXN3@203682|Planctomycetes 203682|Planctomycetes S Phage terminase large subunit (GpA) - - - - - - - - - - - - Terminase_GpA k59_346067_1 1403946.Q615_SPAC00131G0040 4.77e-37 141.0 COG4626@1|root,COG4626@2|Bacteria,1TPU1@1239|Firmicutes,4HAXI@91061|Bacilli 91061|Bacilli L Terminase - - - - - - - - - - - - Terminase_1 k59_346068_2 497964.CfE428DRAFT_3201 3.9e-22 103.0 COG1475@1|root,COG1475@2|Bacteria 2|Bacteria K chromosome segregation - - - - - - - - - - - - MT-A70,ParBc,RepB k59_320693_1 1038860.AXAP01000015_gene1988 2.33e-17 81.6 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2TSDW@28211|Alphaproteobacteria,3JTQV@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_320693_2 348824.LPU83_0595 3.42e-182 537.0 COG3740@1|root,COG3740@2|Bacteria,1QVIJ@1224|Proteobacteria,2TVIM@28211|Alphaproteobacteria,4BNVZ@82115|Rhizobiaceae 28211|Alphaproteobacteria S Phage capsid family - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_54488_1 1122201.AUAZ01000017_gene2950 7.99e-35 131.0 COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,1RY1X@1236|Gammaproteobacteria,46BED@72275|Alteromonadaceae 1236|Gammaproteobacteria S associated with various cellular activities - - - - - - - - - - - - AAA,AAA_5 k59_54488_2 113355.CM001775_gene3638 2.17e-27 119.0 COG3864@1|root,COG3864@2|Bacteria,1G20V@1117|Cyanobacteria 1117|Cyanobacteria S metallopeptidase (DUF2201) - - - - - - - - - - - - DUF2201,DUF2201_N k59_590445_1 867902.Ornrh_0783 7.76e-19 82.4 2C8RN@1|root,32RMQ@2|Bacteria,4NSD0@976|Bacteroidetes,1I3WH@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_569413_1 679189.HMPREF9019_0902 4.13e-08 53.5 COG1044@1|root,COG1044@2|Bacteria 2|Bacteria M lipid A biosynthetic process - - - - - - - - - - - - Hexapep k59_182659_3 1392489.JPOL01000002_gene2839 4.64e-42 161.0 COG1061@1|root,COG1061@2|Bacteria,4NECV@976|Bacteroidetes,1HWX1@117743|Flavobacteriia,2XIJU@283735|Leeuwenhoekiella 976|Bacteroidetes L helicase superfamily c-terminal domain res - - - - - - - - - - - Helicase_C,ResIII k59_469241_1 1234888.K0A2J2_9VIRU 7.09e-73 238.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_610763_1 1481785.A0A068Q5W4_9CAUD 7.84e-40 142.0 4QAUT@10239|Viruses,4QVIM@35237|dsDNA viruses no RNA stage,4QQ7X@28883|Caudovirales,4QNET@10744|Podoviridae 10744|Podoviridae S DNA ligase (ATP) activity - - - - - - - - - - - - - k59_610763_2 596324.TREVI0001_0553 3.6e-20 97.8 COG0208@1|root,COG0208@2|Bacteria,2J642@203691|Spirochaetes 203691|Spirochaetes F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdB - 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_sm k59_610763_3 1007105.PT7_P024 3.02e-12 68.9 2DP75@1|root,330U8@2|Bacteria,1N8XA@1224|Proteobacteria,2VXCX@28216|Betaproteobacteria,3T4S7@506|Alcaligenaceae 28216|Betaproteobacteria S to Bacteriophage phiYeO3-12 1.45 protein 1.45 SWALL Q9T140 (EMBL AJ251805) (157 aa) fasta scores E() 2.6e-06, 36.06 id in 122 aa, and to Escherichia coli O157 H7 - - - - - - - - - - - - AP2,HNH_3 k59_282384_1 1618254.A0A0C5IBG4_9CIRC 4.21e-47 162.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_219152_4 294631.Q5ZGE9_9CAUD 4.24e-22 91.7 4QBCW@10239|Viruses,4QUN6@35237|dsDNA viruses no RNA stage,4QPS7@28883|Caudovirales,4QKNA@10699|Siphoviridae 10699|Siphoviridae S Phage gp6-like head-tail connector protein - - - - - - - - - - - - - k59_264921_1 105154.Q9MBU6_9VIRU 2.22e-65 217.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_264921_2 105154.Q9MBU3_9VIRU 1.05e-16 81.3 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_264921_6 1385658.U5KPZ6_9VIRU 5.64e-102 318.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_116453_1 1435356.Y013_24780 1.57e-23 95.5 2AV81@1|root,31KYQ@2|Bacteria,2HHXC@201174|Actinobacteria,4G1GW@85025|Nocardiaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_159882_1 1434929.X946_2448 1.18e-08 61.6 COG0207@1|root,COG0207@2|Bacteria,1RA8U@1224|Proteobacteria,2VX0I@28216|Betaproteobacteria,1K8GE@119060|Burkholderiaceae 28216|Betaproteobacteria F Thymidylate synthase - - 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt k59_430113_3 5762.XP_002679059.1 4.41e-32 123.0 COG5018@1|root,KOG0542@2759|Eukaryota 2759|Eukaryota U exonuclease activity - GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016441,GO:0016458,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019219,GO:0019222,GO:0031047,GO:0031323,GO:0034641,GO:0035194,GO:0040029,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048519,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060147,GO:0060255,GO:0060966,GO:0060968,GO:0065007,GO:0070920,GO:0071704,GO:0080090,GO:0090065,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1900368,GO:1901360 - ko:K18416,ko:K18418 - - - - ko00000,ko01000,ko03019,ko03036 - - - RNase_T k59_57355_1 56110.Oscil6304_5443 7.45e-07 56.2 COG0515@1|root,COG0642@1|root,COG0745@1|root,COG2114@1|root,COG3899@1|root,COG0515@2|Bacteria,COG0745@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,COG3899@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales 1117|Cyanobacteria KLT Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - AAA_16,GAF,HATPase_c,HisKA,Hpt,Pkinase,Response_reg k59_118580_1 428125.CLOLEP_01409 2.97e-134 399.0 COG4626@1|root,COG4626@2|Bacteria,1TT9I@1239|Firmicutes,24AFK@186801|Clostridia,3WNF4@541000|Ruminococcaceae 186801|Clostridia S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_365143_1 2003327.CAPSD_BPCHP 7.28e-18 85.1 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_39869_2 880071.Fleli_2637 0.000336 52.4 COG3291@1|root,COG3420@1|root,COG3866@1|root,COG3291@2|Bacteria,COG3420@2|Bacteria,COG3866@2|Bacteria,4P2UU@976|Bacteroidetes,47Y1J@768503|Cytophagia 976|Bacteroidetes G bacterial surface protein 26-residue repeat - - - - - - - - - - - - CHU_C,DUF1573,DUF285,TSP_3 k59_593524_2 661367.LLO_p0041 2.84e-44 152.0 COG1961@1|root,COG1961@2|Bacteria,1MXXT@1224|Proteobacteria,1S2SK@1236|Gammaproteobacteria,1JE5Q@118969|Legionellales 118969|Legionellales L Resolvase, N terminal domain - - - - - - - - - - - - HTH_7,Resolvase k59_221258_1 504728.K649_15055 1.65e-08 60.1 COG2176@1|root,COG2176@2|Bacteria,1WJJB@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus L DNA polymerase III - - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T k59_221258_4 6500.XP_005108611.1 2.87e-08 60.8 COG1028@1|root,KOG0725@2759|Eukaryota,3A087@33154|Opisthokonta,3C0DB@33208|Metazoa,3DGU6@33213|Bilateria 33208|Metazoa Q Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short,adh_short_C2 k59_365967_1 1234888.K0A2J2_9VIRU 3.07e-56 193.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_119397_1 1234888.K0A2J2_9VIRU 1.16e-49 174.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_40752_2 1247726.MIM_c10900 9.65e-48 159.0 2F14A@1|root,33U5N@2|Bacteria,1RJ2V@1224|Proteobacteria,2W9XY@28216|Betaproteobacteria,3T84G@506|Alcaligenaceae 28216|Betaproteobacteria S Methyltransferase domain - - - - - - - - - - - - - k59_366003_1 1379692.S5SXY7_9CIRC 4.56e-07 56.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_244625_3 1353529.M899_2309 4.24e-06 53.9 COG2911@1|root,COG3209@1|root,COG2911@2|Bacteria,COG3209@2|Bacteria,1QY1R@1224|Proteobacteria,43C93@68525|delta/epsilon subdivisions,2MUT2@213481|Bdellovibrionales,2X7JI@28221|Deltaproteobacteria 213481|Bdellovibrionales M cell wall surface anchor family protein - - - - - - - - - - - - Peptidase_S74 k59_40761_1 344747.PM8797T_10219 1.53e-44 159.0 COG2401@1|root,COG2401@2|Bacteria,2IYZ0@203682|Planctomycetes 203682|Planctomycetes K acetyltransferase - - - - - - - - - - - - - k59_409774_1 156889.Mmc1_2604 8.99e-70 226.0 COG1475@1|root,COG4725@1|root,COG1475@2|Bacteria,COG4725@2|Bacteria,1R553@1224|Proteobacteria,2TRP6@28211|Alphaproteobacteria 28211|Alphaproteobacteria KT Belongs to the MT-A70-like family - - - - - - - - - - - - MT-A70 k59_119451_1 1183438.GKIL_2298 5.57e-43 155.0 COG0438@1|root,COG0438@2|Bacteria,1FZZP@1117|Cyanobacteria 1117|Cyanobacteria M PFAM Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k59_82234_3 240302.BN982_00193 9.28e-11 61.2 COG1403@1|root,COG1403@2|Bacteria,1VH3I@1239|Firmicutes,4HQB1@91061|Bacilli 91061|Bacilli V HNH nucleases - - - - - - - - - - - - HNH k59_150_1 1618247.A0A0C5IMK7_9CIRC 9.62e-06 53.5 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_389756_2 1475143.W8SNN0_9CIRC 5.91e-52 180.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_123187_1 1155718.KB891925_gene2435 2.57e-05 50.1 2BN1C@1|root,32GMH@2|Bacteria,2IERF@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_21038_2 942016.E9NIH0_9CAUD 3.36e-165 493.0 4QGA5@10239|Viruses,4QURD@35237|dsDNA viruses no RNA stage,4QT9N@28883|Caudovirales,4QP47@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_21038_5 1476391.X5KNA6_9CAUD 1.34e-67 216.0 4QEMD@10239|Viruses,4R0JN@35237|dsDNA viruses no RNA stage,4QUGF@28883|Caudovirales,4QNXF@10744|Podoviridae 10744|Podoviridae S AAA domain - - - - - - - - - - - - - k59_246848_2 1038860.AXAP01000067_gene8427 8.97e-20 90.9 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,2U6BJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S TIGRFAM phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_410777_1 272630.MexAM1_META1p3950 9.87e-26 108.0 COG2197@1|root,COG2197@2|Bacteria,1NA3X@1224|Proteobacteria,2UHEF@28211|Alphaproteobacteria 28211|Alphaproteobacteria KT HNH endonuclease - - - - - - - - - - - - HNH_3 k59_533748_1 1234888.K0A2J2_9VIRU 3.78e-148 438.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_21044_3 477641.MODMU_1582 2.81e-13 77.8 COG0739@1|root,COG0739@2|Bacteria,2GXEC@201174|Actinobacteria 201174|Actinobacteria M peptidase - - - - - - - - - - - - Peptidase_M23 k59_144075_4 1038867.AXAY01000025_gene2082 3.73e-22 102.0 COG0417@1|root,COG0417@2|Bacteria,1R7PE@1224|Proteobacteria,2TRUR@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DNA replication proofreading - - - - - - - - - - - - - k59_205381_1 693272.E3T4M9_CROVB 1.66e-13 82.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage 10239|Viruses S N-methyltransferase activity - GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0097159,GO:1901363 - - - - - - - - - - - k59_533755_1 278957.ABEA03000120_gene1207 1.07e-26 107.0 2CMPB@1|root,32SF8@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - SprT-like k59_554333_1 305700.B447_10643 3.5e-30 115.0 COG2197@1|root,COG2197@2|Bacteria,1NA3X@1224|Proteobacteria,2VW90@28216|Betaproteobacteria 28216|Betaproteobacteria KT HNH endonuclease - - - - - - - - - - - - HNH_3 k59_349185_1 1429046.RR21198_0302 6.69e-06 56.6 2EC0B@1|root,335ZK@2|Bacteria,2I86C@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_349185_3 309803.CTN_0223 5.74e-07 51.6 COG1351@1|root,COG1351@2|Bacteria,2GC26@200918|Thermotogae 200918|Thermotogae F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant thyX - 2.1.1.148 ko:K03465 ko00240,ko00670,ko01100,map00240,map00670,map01100 - R06613 RC00022,RC00332 ko00000,ko00001,ko01000 - - - Thy1 k59_185235_1 288000.BBta_6866 0.000455 40.8 COG3750@1|root,COG3750@2|Bacteria,1N77J@1224|Proteobacteria,2UFX6@28211|Alphaproteobacteria,3JZE3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Belongs to the UPF0335 family MA20_03860 - - - - - - - - - - - DUF2312 k59_636826_3 1175654.A0A0S0NAI5_9CAUD 3e-10 59.7 4QCT7@10239|Viruses,4QVJT@35237|dsDNA viruses no RNA stage,4QPFU@28883|Caudovirales,4QKS9@10699|Siphoviridae 10699|Siphoviridae S iron-sulfur cluster binding - - - - - - - - - - - - - k59_411031_1 1173020.Cha6605_4391 3.1e-39 149.0 COG0442@1|root,COG0442@2|Bacteria,1G238@1117|Cyanobacteria 1117|Cyanobacteria J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS proS - 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iJN678.proS HGTP_anticodon,tRNA-synt_2b,tRNA_edit k59_267729_1 1235800.C819_01431 4.81e-47 180.0 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,2487V@186801|Clostridia,27JEU@186928|unclassified Lachnospiraceae 186801|Clostridia L DNA polymerase A domain - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_267729_3 999411.HMPREF1092_03279 7.11e-38 135.0 28J2E@1|root,2Z8YX@2|Bacteria,1TRF9@1239|Firmicutes,249U3@186801|Clostridia,36EHP@31979|Clostridiaceae 186801|Clostridia S Protein of unknown function (DUF2815) - - - - - - - - - - - - DUF2815 k59_452204_1 1234888.K0A2J2_9VIRU 4.91e-89 281.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_431643_2 1316932.MHH_c12920 3.55e-29 110.0 2AMM7@1|root,31CH8@2|Bacteria,1RJ8Y@1224|Proteobacteria,1SAP1@1236|Gammaproteobacteria,1Y8V6@135625|Pasteurellales 135625|Pasteurellales L Pyrimidine dimer DNA glycosylase denV - 3.1.25.1 ko:K01161 - - - - ko00000,ko01000 - - - Pyr_excise k59_349800_1 661087.HMPREF1008_01479 2.23e-10 67.0 COG1674@1|root,COG1674@2|Bacteria,2GK3T@201174|Actinobacteria,4CU9F@84998|Coriobacteriia 84998|Coriobacteriia D FtsK SpoIIIE family - - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma k59_493564_2 573061.Clocel_0761 2.75e-19 95.1 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,2487V@186801|Clostridia,36EDD@31979|Clostridiaceae 186801|Clostridia L DNA polymerase - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_431680_1 1123059.KB823011_gene873 4.15e-14 75.9 COG5323@1|root,COG5323@2|Bacteria,1MW8S@1224|Proteobacteria,2TREI@28211|Alphaproteobacteria,43WIM@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_1417_1 682795.AciX8_3781 0.000103 51.2 COG1475@1|root,COG1475@2|Bacteria,3Y2KS@57723|Acidobacteria,2JIEE@204432|Acidobacteriia 204432|Acidobacteriia K Belongs to the ParB family - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_226623_3 1589746.A0A0B5A6P7_9CAUD 4.66e-47 177.0 4QB5I@10239|Viruses,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_535581_2 1121479.AUBS01000026_gene393 4.53e-12 66.2 COG1396@1|root,COG1396@2|Bacteria,1RK54@1224|Proteobacteria,2UC16@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Transcriptional - - - - - - - - - - - - HTH_19,HTH_3 k59_576341_1 1205681.CALW02000053_gene1472 3.1e-10 66.2 COG1044@1|root,COG1044@2|Bacteria,1QYEK@1224|Proteobacteria,2TXQB@28211|Alphaproteobacteria,48T4F@772|Bartonellaceae 28211|Alphaproteobacteria M Homologous to orf229 gp Streptococcus thermophilus bacteriophage Sfi19 gi 9632919 ref NP_049948.1 - - - - - - - - - - - - - k59_350486_1 172088.AUGA01000082_gene6213 1.53e-41 153.0 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,2U6BJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S TIGRFAM phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_84328_4 204669.Acid345_0849 4.94e-20 102.0 COG3299@1|root,COG3299@2|Bacteria,3Y440@57723|Acidobacteria,2JI7B@204432|Acidobacteriia 204432|Acidobacteriia S homolog of phage Mu protein gp47 - - - - - - - - - - - - Baseplate_J k59_576344_3 1385658.U5KPZ6_9VIRU 1.63e-29 117.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_2150_2 1416760.AYMS01000142_gene640 2.27e-11 77.4 COG1196@1|root,COG1196@2|Bacteria,4NUKP@976|Bacteroidetes,1I4MA@117743|Flavobacteriia 976|Bacteroidetes D nuclear chromosome segregation - - - - - - - - - - - - - k59_268834_1 1692249.A0A0K1RLN8_9CIRC 1.1e-11 70.1 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_432569_1 1986029.Q9MBM8_9VIRU 8.84e-30 117.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_494270_1 716544.wcw_0487 4.27e-28 108.0 COG1845@1|root,COG1845@2|Bacteria,2JFY3@204428|Chlamydiae 204428|Chlamydiae C Cytochrome c oxidase subunit III cyoC - - ko:K02299 ko00190,ko01100,map00190,map01100 M00417 - - ko00000,ko00001,ko00002 3.D.4.5 - - COX3 k59_494270_2 1267600.JFGT01000005_gene2953 1.02e-19 84.7 COG3125@1|root,COG3125@2|Bacteria,1RHE5@1224|Proteobacteria,1S6KQ@1236|Gammaproteobacteria,3W0QG@53335|Pantoea 1236|Gammaproteobacteria C Cytochrome o ubiquinol oxidase subunit IV cyoD GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009319,GO:0009486,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015453,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016491,GO:0019646,GO:0022804,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0070069,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1902494,GO:1902600 - ko:K02300 ko00190,ko01100,map00190,map01100 M00417 - - ko00000,ko00001,ko00002 3.D.4.5 - iAF1260.b0429,iB21_1397.B21_00384,iBWG_1329.BWG_0311,iE2348C_1286.E2348C_0364,iEC042_1314.EC042_0467,iEC55989_1330.EC55989_0443,iECBD_1354.ECBD_3229,iECB_1328.ECB_00380,iECDH10B_1368.ECDH10B_0385,iECDH1ME8569_1439.ECDH1ME8569_0414,iECD_1391.ECD_00380,iECED1_1282.ECED1_0452,iECH74115_1262.ECH74115_0513,iECIAI1_1343.ECIAI1_0432,iECIAI39_1322.ECIAI39_0244,iECO103_1326.ECO103_0406,iECO111_1330.ECO111_0462,iECO26_1355.ECO26_0464,iECOK1_1307.ECOK1_0409,iECP_1309.ECP_0489,iECS88_1305.ECS88_0425,iECSE_1348.ECSE_0454,iECSF_1327.ECSF_0389,iECSP_1301.ECSP_0497,iECUMN_1333.ECUMN_0468,iECW_1372.ECW_m0501,iECs_1301.ECs0483,iEKO11_1354.EKO11_3417,iEcDH1_1363.EcDH1_3180,iEcE24377_1341.EcE24377A_0464,iEcHS_1320.EcHS_A0504,iEcSMS35_1347.EcSMS35_0469,iEcolC_1368.EcolC_3204,iG2583_1286.G2583_0541,iJO1366.b0429,iJR904.b0429,iLF82_1304.LF82_0407,iNRG857_1313.NRG857_02020,iSBO_1134.SBO_0323,iSSON_1240.SSON_0412,iUMN146_1321.UM146_15215,iUMNK88_1353.UMNK88_479,iUTI89_1310.UTI89_C0452,iWFL_1372.ECW_m0501,iY75_1357.Y75_RS02215,iYL1228.KPN_00391,iZ_1308.Z0532 COX4_pro k59_596547_1 592015.HMPREF1705_00115 1.61e-15 72.8 COG2359@1|root,COG2359@2|Bacteria,3TBE1@508458|Synergistetes 508458|Synergistetes S PFAM Stage V sporulation protein S - - - ko:K06416 - - - - ko00000 - - - SpoVS k59_22455_1 1249997.JHZW01000002_gene1546 5.45e-13 82.8 COG3291@1|root,COG4254@1|root,COG4412@1|root,COG4733@1|root,COG4886@1|root,COG5184@1|root,COG3291@2|Bacteria,COG4254@2|Bacteria,COG4412@2|Bacteria,COG4733@2|Bacteria,COG4886@2|Bacteria,COG5184@2|Bacteria,4NF17@976|Bacteroidetes,1IJNI@117743|Flavobacteriia 976|Bacteroidetes O Mycoplasma protein of unknown function, DUF285 - - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - DUF285,LRR_5 k59_248613_1 445974.CLORAM_02936 7.55e-24 110.0 COG1783@1|root,COG1783@2|Bacteria,1TRQP@1239|Firmicutes,3VRP7@526524|Erysipelotrichia 526524|Erysipelotrichia S Phage terminase, large subunit, PBSX family - - - - - - - - - - - - Terminase_3,Terminase_3C k59_248613_2 1232447.BAHW02000040_gene2764 5.8e-12 68.6 COG0732@1|root,COG0732@2|Bacteria,1V2VF@1239|Firmicutes,24WBX@186801|Clostridia,26CBI@186813|unclassified Clostridiales 186801|Clostridia V Type I restriction modification DNA specificity domain - - - - - - - - - - - - Methylase_S k59_555675_1 1234888.K0A2J2_9VIRU 1.18e-39 147.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_535630_2 195522.BD01_0567 1.24e-10 67.4 COG0675@1|root,arCOG00683@2157|Archaea,2XUAH@28890|Euryarchaeota,242SS@183968|Thermococci 183968|Thermococci L Probable transposase - - - ko:K07496 - - - - ko00000 - - - OrfB_IS605,OrfB_Zn_ribbon k59_412220_2 1538804.A0A088FAP5_9CAUD 1.04e-36 132.0 4QB0T@10239|Viruses,4QPUT@28883|Caudovirales,4QKQK@10699|Siphoviridae 10699|Siphoviridae S Protein of unknown function (DUF669) - - - - - - - - - - - - - k59_337709_1 1986029.Q9MBM3_9VIRU 7.68e-17 85.5 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_273979_1 1038860.AXAP01000067_gene8427 1.03e-31 125.0 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,2U6BJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S TIGRFAM phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_459541_1 47716.JOFH01000001_gene2364 1.24e-27 117.0 2DWRB@1|root,341IF@2|Bacteria,2ID68@201174|Actinobacteria 201174|Actinobacteria S Domain of unknown function (DUF5047) - - - - - - - - - - - - DUF5047 k59_47502_1 1234888.K0A2J2_9VIRU 5.6e-55 188.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_602300_1 1618248.A0A0C5IB82_9CIRC 1.15e-74 238.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_91207_1 926556.Echvi_4181 1.49e-38 155.0 COG1961@1|root,COG1961@2|Bacteria,4NFJA@976|Bacteroidetes,47RIT@768503|Cytophagia 976|Bacteroidetes L Site-specific recombinase, DNA invertase Pin - - - - - - - - - - - - Recombinase,Resolvase,Zn_ribbon_recom k59_500130_1 1121865.OMW_01120 2.27e-08 60.5 COG4469@1|root,COG4469@2|Bacteria,1TRGD@1239|Firmicutes,4HFP5@91061|Bacilli,4B2RU@81852|Enterococcaceae 91061|Bacilli S Competence protein CoiA-like family coiA - - ko:K06198 - - - - ko00000 - - - CoiA k59_561525_1 483216.BACEGG_02721 8.29e-10 68.2 2F135@1|root,33U4N@2|Bacteria,4P2MK@976|Bacteroidetes,2FTM1@200643|Bacteroidia,4AT68@815|Bacteroidaceae 976|Bacteroidetes S Capsid protein (F protein) - - - - - - - - - - - - Phage_F k59_131761_1 1385658.U5KPZ6_9VIRU 4.86e-22 94.7 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_47937_1 1692257.A0A0K1RL39_9CIRC 3.22e-24 102.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_108596_1 155864.EDL933_1740 5.72e-05 51.2 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,1RPEK@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Terminase - - - - - - - - - - - - Terminase_1 k59_314548_1 1563661.A0A097PAJ0_9CAUD 1.59e-06 54.7 4QBMV@10239|Viruses,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_500143_2 1692249.A0A0K1RLN8_9CIRC 8.1e-71 223.0 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_530519_1 411902.CLOBOL_04837 7.73e-19 86.3 COG0791@1|root,COG3772@1|root,COG0791@2|Bacteria,COG3772@2|Bacteria,1VG3D@1239|Firmicutes,25FTG@186801|Clostridia,223QR@1506553|Lachnoclostridium 186801|Clostridia M Phage lysozyme - - - - - - - - - - - - - k59_530519_2 365044.Pnap_4462 1.72e-26 105.0 2CWXD@1|root,32T0J@2|Bacteria,1N3Z7@1224|Proteobacteria,2VVQI@28216|Betaproteobacteria,4AID3@80864|Comamonadaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_550902_1 227377.CBU_2083 1.81e-09 60.5 COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,1RMG9@1236|Gammaproteobacteria,1JC8U@118969|Legionellales 118969|Legionellales F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) queC - 6.3.4.20 ko:K06920 ko00790,ko01100,map00790,map01100 - R09978 RC00959 ko00000,ko00001,ko01000,ko03016 - - - QueC k59_550902_2 879243.Poras_1677 2.3e-57 182.0 COG0720@1|root,COG0720@2|Bacteria,4PIUG@976|Bacteroidetes,2FSF1@200643|Bacteroidia,22Z05@171551|Porphyromonadaceae 976|Bacteroidetes H 6-pyruvoyl tetrahydrobiopterin synthase queD - 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 - - - PTPS k59_33837_1 234267.Acid_5770 1.08e-17 90.1 COG4625@1|root,COG4932@1|root,COG4625@2|Bacteria,COG4932@2|Bacteria,3Y354@57723|Acidobacteria 57723|Acidobacteria M PKD domain containing protein - - - - - - - - - - - - He_PIG k59_301100_2 1121448.DGI_4068 5.95e-18 86.7 COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,42QA8@68525|delta/epsilon subdivisions,2WJBW@28221|Deltaproteobacteria,2M8NS@213115|Desulfovibrionales 28221|Deltaproteobacteria S PFAM ATPase associated with various cellular activities - - - - - - - - - - - - AAA_3,AAA_5 k59_588073_1 10736.A0A1P8CWY5_BPPHT 4.54e-07 53.5 4QAUT@10239|Viruses,4QVIM@35237|dsDNA viruses no RNA stage,4QQ7X@28883|Caudovirales 28883|Caudovirales S DNA ligase (ATP) activity - - - - - - - - - - - - - k59_33854_1 391038.Bphy_1919 1.19e-22 94.4 COG2197@1|root,COG2197@2|Bacteria,1NA3X@1224|Proteobacteria,2VWX0@28216|Betaproteobacteria,1KAW7@119060|Burkholderiaceae 28216|Betaproteobacteria KT phage-related functions and prophages - - - - - - - - - - - - HNH_3 k59_505616_1 272560.BPSL1143 3.12e-15 77.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2VNHP@28216|Betaproteobacteria,1K7BW@119060|Burkholderiaceae 28216|Betaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_279844_2 742733.HMPREF9469_05036 2.5e-50 165.0 2AIHK@1|root,318ZG@2|Bacteria,1V7P0@1239|Firmicutes,24KNU@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_238371_3 1609634.A0A0C5AFV4_9VIRU 1.93e-20 90.9 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_346005_1 658187.LDG_6493 3.72e-18 88.6 COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,1RMB8@1236|Gammaproteobacteria,1JDNX@118969|Legionellales 118969|Legionellales S RmuC family rmuC - - ko:K09760 - - - - ko00000 - - - RmuC k59_100065_1 1105386.G8E3Y4_9CIRC 1.46e-30 121.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_100065_2 1618236.A0A0C5I2F3_9CIRC 2.68e-38 144.0 4QGVY@10239|Viruses,4QUKN@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_608535_2 78398.KS43_20465 5.02e-22 102.0 COG0749@1|root,COG0749@2|Bacteria,1MWX7@1224|Proteobacteria,1S0Q1@1236|Gammaproteobacteria 1236|Gammaproteobacteria L ORF located using Glimmer RBSfinder - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A,DNA_pol_A_exo1 k59_33877_1 1385658.U5KQQ9_9VIRU 3.93e-05 50.8 4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_156620_1 1406780.U5PZU8_9CAUD 3.1e-15 80.5 4QBMV@10239|Viruses,4QUU6@35237|dsDNA viruses no RNA stage,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_448325_2 1347392.CCEZ01000024_gene791 0.000844 40.8 28IN7@1|root,2Z8NM@2|Bacteria,1U60P@1239|Firmicutes,249JG@186801|Clostridia,36HNF@31979|Clostridiaceae 186801|Clostridia S Capsid protein (F protein) - - - - - - - - - - - - Phage_F k59_245902_1 13690.CP98_01297 1.64e-05 52.4 COG1196@1|root,COG1196@2|Bacteria 2|Bacteria D nuclear chromosome segregation - - - ko:K10953 ko05110,map05110 - - - ko00000,ko00001,ko02042 - - - Peptidase_C80,RtxA,TMP_2 k59_223621_1 1056820.KB900699_gene1252 4.27e-08 64.7 COG3291@1|root,COG3291@2|Bacteria,1RCBA@1224|Proteobacteria,1T3K8@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Mycoplasma protein of unknown function, DUF285 - - - - - - - - - - - - DUF11,DUF285 k59_367754_1 334413.FMG_P0072 3.07e-06 55.5 COG0270@1|root,COG0270@2|Bacteria,1TSNX@1239|Firmicutes,2490C@186801|Clostridia,22G1X@1570339|Peptoniphilaceae 186801|Clostridia L C-5 cytosine-specific DNA methylase haeIIIM - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_223695_6 1234888.K0A2J2_9VIRU 6.97e-95 303.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_163659_1 1096546.WYO_0193 3.46e-50 171.0 28JC4@1|root,2Z96S@2|Bacteria,1RI8W@1224|Proteobacteria 1224|Proteobacteria S P22 coat protein-protein 5 domain protein - - - - - - - - - - - - - k59_121263_2 1305737.JAFX01000001_gene2807 2.33e-12 66.6 COG0566@1|root,COG0566@2|Bacteria,4NM8C@976|Bacteroidetes,47PEY@768503|Cytophagia 976|Bacteroidetes J PFAM SpoU rRNA Methylase family spoU - - - - - - - - - - - SpoU_methylase k59_223782_1 1280685.AUKC01000014_gene3 5.36e-50 175.0 COG0773@1|root,COG0773@2|Bacteria,1VTVI@1239|Firmicutes,24Y9A@186801|Clostridia,4C1ZN@830|Butyrivibrio 186801|Clostridia M Mur ligase family, catalytic domain - - - - - - - - - - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k59_143528_1 298653.Franean1_1236 1.08e-36 139.0 COG1626@1|root,COG1626@2|Bacteria,2I1MU@201174|Actinobacteria,4ESP9@85013|Frankiales 201174|Actinobacteria G Trehalase - - - - - - - - - - - - Glyco_hydro_63,Trehalase k59_184536_2 1618248.A0A0C5IB82_9CIRC 1.96e-06 52.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_225550_1 4155.Migut.J01770.1.p 6.76e-37 142.0 COG0481@1|root,KOG0462@2759|Eukaryota,37K2D@33090|Viridiplantae,3GBUJ@35493|Streptophyta,44C9D@71274|asterids 35493|Streptophyta J Elongation factor G C-terminus - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009507,GO:0009536,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031647,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050821,GO:0050896,GO:0065007,GO:0065008,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K06207 - - - - ko00000 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2 k59_123032_1 1788449.A0A190WHL0_9CIRC 2.39e-35 130.0 4QBFZ@10239|Viruses,4QUKU@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_328071_2 1123008.KB905702_gene2353 6.25e-12 65.9 COG1783@1|root,COG1783@2|Bacteria,4NHPB@976|Bacteroidetes,2FR95@200643|Bacteroidia,22WQM@171551|Porphyromonadaceae 976|Bacteroidetes S Terminase RNAseH like domain - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C k59_225555_2 1235799.C818_04202 2.18e-74 246.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,27J0X@186928|unclassified Lachnospiraceae 186801|Clostridia KL SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,SNF2_N k59_143548_2 399739.Pmen_0185 1.45e-10 67.0 COG0739@1|root,COG0739@2|Bacteria,1RIS0@1224|Proteobacteria,1S6KP@1236|Gammaproteobacteria,1YD3S@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria M Peptidase family M23 - - - - - - - - - - - - DUF4124,Peptidase_M23 k59_184559_1 906668.G8C7I3_9CAUD 1.82e-97 301.0 4QBV3@10239|Viruses,4QW0W@35237|dsDNA viruses no RNA stage,4QPPJ@28883|Caudovirales,4QKW5@10699|Siphoviridae 10699|Siphoviridae S Phage Terminase - - - - - - - - - - - - - k59_492116_1 105154.Q9MBU0_9VIRU 1.31e-36 136.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_492116_4 105154.Q9MBU3_9VIRU 1.9e-10 65.1 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_597698_3 500153.JOEK01000002_gene330 8.75e-32 119.0 COG0739@1|root,COG0739@2|Bacteria,2IFNV@201174|Actinobacteria 201174|Actinobacteria M Peptidase family M23 - - - - - - - - - - - - PG_binding_1,Peptidase_M23 k59_290237_1 442493.A8E284_BPPHE 2.74e-18 97.8 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QIPS@10662|Myoviridae 10662|Myoviridae S N-acetylmuramoyl-L-alanine amidase activity - - - - - - - - - - - - - k59_23487_2 29540.C481_11105 1.92e-05 52.0 COG5410@1|root,arCOG09550@2157|Archaea,2Y627@28890|Euryarchaeota,240H1@183963|Halobacteria 183963|Halobacteria K chromosome segregation - - - - - - - - - - - - - k59_351317_1 1481112.A0A023W6W3_9CAUD 6.16e-15 73.2 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QI82@10662|Myoviridae 10662|Myoviridae S virus tail, fiber - - - - - - - - - - - - - k59_597707_1 1173762.S4TT67_9CAUD 6.28e-73 233.0 4QCT5@10239|Viruses,4QYJH@35237|dsDNA viruses no RNA stage,4QTPG@28883|Caudovirales,4QNK2@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_249626_1 641526.ADIWIN_3678 1.59e-13 77.0 COG0729@1|root,COG5295@1|root,COG0729@2|Bacteria,COG5295@2|Bacteria,4NJTK@976|Bacteroidetes,1HZNB@117743|Flavobacteriia 976|Bacteroidetes UW surface antigen - - - - - - - - - - - - Peptidase_S74 k59_639519_1 888062.HMPREF9083_0015 5.84e-08 60.5 COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,4H2CW@909932|Negativicutes 909932|Negativicutes L DNA polymerase dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k59_475642_1 1692253.A0A0K1RLM4_9CIRC 2.3e-55 191.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_537116_1 105154.Q9MBU6_9VIRU 9.13e-49 174.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_455242_1 455632.SGR_3347 1.29e-16 77.0 COG0270@1|root,COG0270@2|Bacteria,2GNB2@201174|Actinobacteria,41CRY@629295|Streptomyces griseus group 201174|Actinobacteria L DNA (cytosine-5-)-methyltransferase activity - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_376768_2 110365.A0A023AX31 1.08e-27 116.0 2EWQP@1|root,2SYH6@2759|Eukaryota 2759|Eukaryota S RNA helicase - - - - - - - - - - - - RNA_helicase,Viral_Rep k59_69223_1 1206730.BAGA01000174_gene2167 5.27e-23 103.0 COG0392@1|root,COG0671@1|root,COG3642@1|root,COG0392@2|Bacteria,COG0671@2|Bacteria,COG3642@2|Bacteria,2GMAV@201174|Actinobacteria,4FXZC@85025|Nocardiaceae 201174|Actinobacteria IT Lysylphosphatidylglycerol synthase TM region - - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - LPG_synthase_TM,PAP2 k59_560925_1 272134.KB731324_gene3692 1.78e-23 103.0 COG3409@1|root,COG3409@2|Bacteria,1GDBE@1117|Cyanobacteria,1HFCB@1150|Oscillatoriales 1117|Cyanobacteria M Pfam:DUF3380 - - - - - - - - - - - - Muraidase,PG_binding_1 k59_646012_2 234267.Acid_6035 9.58e-13 68.6 COG1403@1|root,COG1403@2|Bacteria 2|Bacteria V endonuclease activity - - - - - - - - - - - - HNH k59_355295_2 483216.BACEGG_03178 3.27e-10 68.2 COG3378@1|root,COG3378@2|Bacteria,4NG1J@976|Bacteroidetes,2FQRK@200643|Bacteroidia,4AQ5P@815|Bacteroidaceae 976|Bacteroidetes S Phage plasmid primase, P4 family domain protein - - - ko:K06919 - - - - ko00000 - - - D5_N,Pox_D5 k59_211313_1 1123237.Salmuc_03412 4.16e-103 310.0 COG1403@1|root,COG1403@2|Bacteria,1QE4E@1224|Proteobacteria 1224|Proteobacteria L HNH endonuclease - - - - - - - - - - - - HNH,HNH_5,RRXRR k59_338072_1 105154.Q9MBU6_9VIRU 4.33e-55 188.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_338072_3 1165094.RINTHH_3920 9.24e-65 213.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_646591_1 1556290.A0A0A0RL61_9CAUD 5.02e-46 158.0 4QAK6@10239|Viruses,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - GO:0005575,GO:0019012,GO:0019028,GO:0032991,GO:0044423,GO:0046806 - - - - - - - - - - - k59_91581_3 656519.Halsa_1785 1.66e-76 243.0 COG1397@1|root,COG1397@2|Bacteria,1TQXG@1239|Firmicutes,24C2X@186801|Clostridia 186801|Clostridia O PFAM ADP-ribosylation Crystallin J1 - - 3.2.2.24 ko:K05521 - - - - ko00000,ko01000 - - - ADP_ribosyl_GH k59_69655_1 273068.TTE2069 1.6e-11 72.8 COG1475@1|root,COG1475@2|Bacteria,1V4KU@1239|Firmicutes,24IEQ@186801|Clostridia,42GN3@68295|Thermoanaerobacterales 186801|Clostridia K CHROMOSOME PARTITIONING PROTEIN PARB gi 11280351 pir D82035 ParB family protein VC2772 imported - Vibrio cholerae (group O1 strain N16961) gi 9657374 gb AAF95911.1 (AE004343) ParB family protein Vibrio cholerae , score - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_28250_1 1500281.JQKZ01000024_gene2768 0.000143 50.1 COG4886@1|root,COG4886@2|Bacteria,4NF17@976|Bacteroidetes,1IJNI@117743|Flavobacteriia,3ZUQS@59732|Chryseobacterium 976|Bacteroidetes U Mycoplasma protein of unknown function, DUF285 - - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - DUF285,LRR_5 k59_602572_1 1123313.ATUT01000011_gene1479 3.1e-57 193.0 COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,3VP17@526524|Erysipelotrichia 526524|Erysipelotrichia L Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N k59_543266_1 1395516.PMO01_03075 8.76e-16 79.3 2DP75@1|root,330U8@2|Bacteria,1N8XA@1224|Proteobacteria,1SCZN@1236|Gammaproteobacteria 1236|Gammaproteobacteria S HNH endonuclease - - - - - - - - - - - - AP2,HNH_3 k59_608180_1 1536769.P40081_01135 2.7e-16 82.4 COG4409@1|root,COG4409@2|Bacteria,1UPKZ@1239|Firmicutes 1239|Firmicutes G exo-alpha-(2->6)-sialidase activity - - - - - - - - - - - - - k59_608180_2 322710.Avin_51230 1.11e-11 74.3 COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q COG2931 RTX toxins and related Ca2 -binding proteins psmE - - - - - - - - - - - Beta_helix,Cadherin_3,DUF4114,He_PIG,HemolysinCabind,Pectate_lyase_3,Peptidase_M10,Peptidase_M10_C k59_137833_3 397945.Aave_2353 5.85e-06 52.8 COG4626@1|root,COG4626@2|Bacteria 2|Bacteria S Terminase - - - - - - - - - - - - Terminase_1 k59_280129_4 1166018.FAES_1949 7.16e-08 56.2 2AFQQ@1|root,315SK@2|Bacteria,4NJD4@976|Bacteroidetes,47PFM@768503|Cytophagia 976|Bacteroidetes S NUMOD4 motif - - - - - - - - - - - - HNH_3,NUMOD4 k59_280129_15 66692.ABC1368 1.72e-16 92.8 COG3378@1|root,COG4983@1|root,COG3378@2|Bacteria,COG4983@2|Bacteria,1TQP9@1239|Firmicutes,4HBTB@91061|Bacilli,1ZEU3@1386|Bacillus 91061|Bacilli S D5 N terminal like - - - ko:K06919 - - - - ko00000 - - - D5_N,Pox_D5,PriCT_1,Prim-Pol k59_224926_1 1121396.KB892966_gene957 3.92e-16 85.1 COG0305@1|root,COG3598@1|root,COG0305@2|Bacteria,COG3598@2|Bacteria,1R4EA@1224|Proteobacteria,42TKF@68525|delta/epsilon subdivisions,2WQ0D@28221|Deltaproteobacteria,2MNNZ@213118|Desulfobacterales 28221|Deltaproteobacteria L AAA domain - - - - - - - - - - - - AAA_25 k59_224926_2 28444.JODQ01000007_gene5819 1.13e-06 54.3 28NEI@1|root,2ZBH3@2|Bacteria,2I25R@201174|Actinobacteria,4EQGR@85012|Streptosporangiales 201174|Actinobacteria - - - - - - - - - - - - - - - k59_60645_1 1157708.KB907450_gene5797 1.17e-51 172.0 COG0745@1|root,COG0745@2|Bacteria,1PDAM@1224|Proteobacteria,2VZJG@28216|Betaproteobacteria,4AHQU@80864|Comamonadaceae 28216|Betaproteobacteria T Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Response_reg,Trans_reg_C k59_635748_2 28985.XP_452850.1 4.93e-69 238.0 COG0464@1|root,KOG0741@2759|Eukaryota,38CBE@33154|Opisthokonta,3NV43@4751|Fungi,3QKQE@4890|Ascomycota,3RSNZ@4891|Saccharomycetes,3RYK5@4893|Saccharomycetaceae 4751|Fungi O to Saccharomyces cerevisiae SEC18 (YBR080C) SEC18 GO:0000045,GO:0000149,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0005829,GO:0005937,GO:0006810,GO:0006886,GO:0006888,GO:0006891,GO:0006892,GO:0006893,GO:0006906,GO:0006914,GO:0006996,GO:0007033,GO:0008104,GO:0008144,GO:0008150,GO:0008152,GO:0008289,GO:0009056,GO:0009987,GO:0012505,GO:0015031,GO:0015833,GO:0016043,GO:0016050,GO:0016192,GO:0016236,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022406,GO:0022411,GO:0022607,GO:0030427,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032984,GO:0033036,GO:0034613,GO:0035494,GO:0035639,GO:0036094,GO:0042144,GO:0042886,GO:0042995,GO:0043001,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043332,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044463,GO:0044464,GO:0045184,GO:0046907,GO:0048193,GO:0048211,GO:0048219,GO:0048278,GO:0048280,GO:0048284,GO:0051179,GO:0051234,GO:0051286,GO:0051640,GO:0051641,GO:0051649,GO:0061024,GO:0061025,GO:0061919,GO:0061951,GO:0070300,GO:0070727,GO:0070925,GO:0071702,GO:0071705,GO:0071840,GO:0072657,GO:0072659,GO:0090150,GO:0090174,GO:0097159,GO:0097367,GO:0097576,GO:0098876,GO:0120025,GO:0120038,GO:0140056,GO:1901265,GO:1901363,GO:1905037,GO:1990778 3.6.4.6 ko:K06027 ko04138,ko04721,ko04727,ko04962,map04138,map04721,map04727,map04962 - - - ko00000,ko00001,ko01000,ko04131 1.F.1.1 - - AAA,CDC48_2,CDC48_N k59_225652_1 1234888.K0A2J2_9VIRU 7.42e-27 109.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_164142_2 690585.JNNU01000002_gene4506 1.29e-67 210.0 2A41J@1|root,30SK4@2|Bacteria,1Q8VC@1224|Proteobacteria,2V3IY@28211|Alphaproteobacteria,4BKPS@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_20603_1 1121935.AQXX01000096_gene2550 1.52e-22 102.0 COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,1MVH7@1224|Proteobacteria,1S09Z@1236|Gammaproteobacteria,1XP1M@135619|Oceanospirillales 135619|Oceanospirillales KL DNA methylase - - - - - - - - - - - - N6_N4_Mtase,ParBc k59_328216_2 760568.Desku_1119 1.61e-09 62.8 2DENI@1|root,2ZNKC@2|Bacteria,1W40M@1239|Firmicutes,256HE@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_287184_1 1123487.KB892865_gene1388 8.23e-08 57.8 COG3378@1|root,COG3378@2|Bacteria 2|Bacteria KL Phage plasmid primase P4 family - - - ko:K06919 - - - - ko00000 - - - PriCT_2,Prim-Pol k59_187380_2 1385658.U5KQQ9_9VIRU 1.08e-08 61.6 4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_597209_1 1732201.A0A0N9N7I3_9CIRC 1.74e-23 103.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_289799_1 942016.E9NIG9_9CAUD 1.12e-64 212.0 4QEG2@10239|Viruses,4QVSD@35237|dsDNA viruses no RNA stage,4QRJ9@28883|Caudovirales,4QP0R@10744|Podoviridae 10744|Podoviridae S exonuclease activity - - - - - - - - - - - - - k59_412782_1 1328029.S0A548_9CAUD 7.98e-55 188.0 4QB9T@10239|Viruses,4R0FI@35237|dsDNA viruses no RNA stage,4QQR9@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_166862_3 1385658.U5KPZ6_9VIRU 1.12e-16 79.7 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_187390_1 105154.Q9MBU3_9VIRU 2.44e-13 70.1 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_187390_2 105154.Q9MBU6_9VIRU 1.34e-157 464.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_371654_2 428125.CLOLEP_01416 1.42e-33 122.0 2ECB3@1|root,3369E@2|Bacteria,1VEV9@1239|Firmicutes,24R69@186801|Clostridia,3WNCY@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_494951_2 1173135.I4DSL7_9CAUD 1.29e-23 99.0 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales,4QKM7@10699|Siphoviridae 10699|Siphoviridae S HNH endonuclease - - - - - - - - - - - - - k59_290086_2 428125.CLOLEP_01409 7.64e-98 301.0 COG4626@1|root,COG4626@2|Bacteria,1TT9I@1239|Firmicutes,24AFK@186801|Clostridia,3WNF4@541000|Ruminococcaceae 186801|Clostridia S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_479528_1 713586.KB900536_gene2649 1.44e-08 60.1 COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1RMSS@1236|Gammaproteobacteria,1WWPX@135613|Chromatiales 135613|Chromatiales L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_int_SAM_4,Phage_integrase k59_129451_1 1121930.AQXG01000001_gene1548 4.57e-10 67.8 COG5164@1|root,COG5164@2|Bacteria,4NT5R@976|Bacteroidetes,1ISIJ@117747|Sphingobacteriia 976|Bacteroidetes K regulation of DNA-templated transcription, elongation - - - - - - - - - - - - LRR_5 k59_335690_4 744979.R2A130_3480 4.15e-19 82.4 COG4725@1|root,COG4725@2|Bacteria,1R553@1224|Proteobacteria,2TRP6@28211|Alphaproteobacteria 28211|Alphaproteobacteria KT Belongs to the MT-A70-like family - - - - - - - - - - - - MT-A70 k59_170855_1 742740.HMPREF9474_02312 7.65e-17 80.1 2B7V5@1|root,3211Y@2|Bacteria,1V7MK@1239|Firmicutes,24JA7@186801|Clostridia,222WR@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_89171_1 115711.CP_0543 1.85e-13 70.1 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_209747_1 1234888.K0A2J2_9VIRU 7.02e-34 132.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_353847_1 1469557.JSWF01000031_gene2027 1.35e-14 78.6 COG0270@1|root,COG0270@2|Bacteria,4NG9A@976|Bacteroidetes,1HYT0@117743|Flavobacteriia 976|Bacteroidetes L C-5 cytosine-specific DNA methylase dcm - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase,Eco57I k59_170870_3 1484157.PSNIH2_13450 7.26e-44 151.0 COG1403@1|root,COG1403@2|Bacteria,1N3CX@1224|Proteobacteria,1S45B@1236|Gammaproteobacteria 1236|Gammaproteobacteria V Bacteriophage Lambda NinG protein - - - - - - - - - - - - NinG k59_600781_1 1457250.BBMO01000002_gene2316 1.64e-13 78.6 arCOG00373@1|root,arCOG00373@2157|Archaea 2157|Archaea - - - - - - - - - - - - - - - k59_26348_1 472175.EL18_01375 4.25e-42 156.0 COG3740@1|root,COG3740@2|Bacteria,1QVIJ@1224|Proteobacteria,2TVIM@28211|Alphaproteobacteria,43N07@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Caudovirus prohead serine protease - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_46042_1 1463901.JOIY01000002_gene1068 3.74e-50 180.0 COG1132@1|root,COG1132@2|Bacteria,2GJWP@201174|Actinobacteria 201174|Actinobacteria V ABC transporter ywjA - - ko:K06147,ko:K18893 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k59_293434_1 756275.H2BCT9_9CAUD 3.88e-15 81.6 4QEXP@10239|Viruses,4QUDQ@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_149639_1 1157635.KB892035_gene6489 3.38e-48 170.0 COG0766@1|root,COG0766@2|Bacteria,2GJPW@201174|Actinobacteria 201174|Actinobacteria M Belongs to the EPSP synthase family. MurA subfamily murA - 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - - EPSP_synthase,HTH_3 k59_462589_1 186617.M9M8L2_9VIRU 2.58e-50 175.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_30688_1 1538804.A0A088F6T3_9CAUD 1.36e-151 451.0 4QAKM@10239|Viruses,4QPEF@28883|Caudovirales,4QKNE@10699|Siphoviridae 10699|Siphoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_153682_2 457405.FSDG_00355 1.16e-18 98.2 COG3378@1|root,COG3378@2|Bacteria,37A1N@32066|Fusobacteria 32066|Fusobacteria S D5 N terminal like - - - ko:K06919 - - - - ko00000 - - - D5_N,Pox_D5 k59_399872_1 935866.JAER01000006_gene3401 3.08e-19 95.1 COG4653@1|root,COG4653@2|Bacteria,2ICZP@201174|Actinobacteria 201174|Actinobacteria S Phage capsid family - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_297964_3 985255.APHJ01000018_gene3092 1e-22 97.4 COG4974@1|root,COG4974@2|Bacteria,4NX3Q@976|Bacteroidetes,1HXCN@117743|Flavobacteriia,2P5WF@244698|Gillisia 976|Bacteroidetes L Arm DNA-binding domain - - - - - - - - - - - - Arm-DNA-bind_5,Phage_int_SAM_5,Phage_integrase k59_462621_1 411460.RUMTOR_01335 4.61e-05 46.6 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_176331_1 374847.Kcr_0638 2.77e-45 164.0 arCOG02559@1|root,arCOG02559@2157|Archaea 2157|Archaea P by modhmm - - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - - k59_463136_1 35343.Q38644_9CAUD 1.06e-29 120.0 4QAQE@10239|Viruses,4QUYF@35237|dsDNA viruses no RNA stage,4QPDM@28883|Caudovirales,4QI70@10662|Myoviridae 10662|Myoviridae S DNA integration - - - - - - - - - - - - - k59_277256_3 1165094.RINTHH_3920 2.79e-50 171.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_380385_2 1267534.KB906755_gene3947 8.65e-23 100.0 COG4974@1|root,COG4974@2|Bacteria,3Y5GN@57723|Acidobacteria,2JJXR@204432|Acidobacteriia 204432|Acidobacteriia L Phage integrase family - - - - - - - - - - - - Phage_integrase k59_31182_1 641526.ADIWIN_3678 2.3e-12 73.9 COG0729@1|root,COG5295@1|root,COG0729@2|Bacteria,COG5295@2|Bacteria,4NJTK@976|Bacteroidetes,1HZNB@117743|Flavobacteriia 976|Bacteroidetes UW surface antigen - - - - - - - - - - - - Peptidase_S74 k59_235747_1 1449357.JQLK01000003_gene2526 3.51e-05 49.3 COG4974@1|root,COG4974@2|Bacteria,1WJ4B@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus L Phage integrase family - - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase k59_527320_1 1385658.U5KPZ6_9VIRU 1.42e-26 115.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_491939_1 316055.RPE_2099 4.49e-23 100.0 COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,2TRQA@28211|Alphaproteobacteria,3JT8T@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 k59_630761_1 32057.KB217474_gene7975 4.97e-40 161.0 COG5545@1|root,COG5545@2|Bacteria,1G4RT@1117|Cyanobacteria,1HNNZ@1161|Nostocales 1117|Cyanobacteria S Virulence-associated protein E - - - - - - - - - - - - RepB_primase,VirE k59_101315_1 1196323.ALKF01000200_gene2705 2.88e-61 199.0 COG0207@1|root,COG0207@2|Bacteria,1TSIR@1239|Firmicutes,4H9QS@91061|Bacilli,26T1B@186822|Paenibacillaceae 91061|Bacilli F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA - 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt k59_347458_7 1476391.X5L106_9CAUD 1.01e-35 134.0 4QH15@10239|Viruses,4QZKH@35237|dsDNA viruses no RNA stage,4QT0Z@28883|Caudovirales,4QP1H@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_347458_8 1476391.X5KNA6_9CAUD 1.94e-68 216.0 4QEMD@10239|Viruses,4R0JN@35237|dsDNA viruses no RNA stage,4QUGF@28883|Caudovirales,4QNXF@10744|Podoviridae 10744|Podoviridae S AAA domain - - - - - - - - - - - - - k59_347458_10 1054461.G0XNU3_9CAUD 1.38e-226 657.0 4QGA5@10239|Viruses,4QURD@35237|dsDNA viruses no RNA stage,4QT9N@28883|Caudovirales,4QP47@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_361320_1 1200352.A606_02455 1.19e-53 193.0 COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,22KC7@1653|Corynebacteriaceae 201174|Actinobacteria P cation transport ATPase - - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 k59_589250_1 1005999.GLGR_1993 2.05e-15 72.8 COG3772@1|root,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,1S99W@1236|Gammaproteobacteria 1236|Gammaproteobacteria G lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_217121_1 648333.Q77NU8_PFDNG 4.81e-10 68.9 4QAUG@10239|Viruses,4QUM5@29258|ssDNA viruses 10239|Viruses L Parvovirus non-structural protein NS1 - GO:0001906,GO:0001907,GO:0005575,GO:0008150,GO:0009889,GO:0010556,GO:0010941,GO:0010942,GO:0016032,GO:0018995,GO:0019048,GO:0019051,GO:0019054,GO:0019056,GO:0019058,GO:0019079,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031341,GO:0031343,GO:0031640,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0035821,GO:0039526,GO:0039592,GO:0039656,GO:0039685,GO:0039693,GO:0042025,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043656,GO:0043657,GO:0043900,GO:0043902,GO:0043903,GO:0044003,GO:0044004,GO:0044068,GO:0044071,GO:0044215,GO:0044216,GO:0044217,GO:0044364,GO:0044403,GO:0044419,GO:0044531,GO:0044532,GO:0044533,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0051701,GO:0051704,GO:0051709,GO:0051712,GO:0051726,GO:0051817,GO:0051818,GO:0051883,GO:0052026,GO:0052040,GO:0052042,GO:0052150,GO:0052151,GO:0052248,GO:0052312,GO:0052330,GO:0052433,GO:0052501,GO:0060139,GO:0060153,GO:0060255,GO:0065007,GO:0080090,GO:2001141 - - - - - - - - - - - k59_450030_1 1123009.AUID01000045_gene1202 6.72e-58 190.0 2E1MQ@1|root,32WYT@2|Bacteria,1VB8R@1239|Firmicutes,24R84@186801|Clostridia,269J6@186813|unclassified Clostridiales 186801|Clostridia - - - - - - - - - - - - - - - k59_609879_1 272563.CD630_09170 5.39e-32 130.0 COG3723@1|root,COG3723@2|Bacteria,1V3B6@1239|Firmicutes,24HHQ@186801|Clostridia 186801|Clostridia L Phage recombination protein Bet bet - - - - - - - - - - - RecT k59_239651_2 987059.RBXJA2T_07753 1.56e-19 90.9 COG2110@1|root,COG2110@2|Bacteria,1MVYN@1224|Proteobacteria,2VH7H@28216|Betaproteobacteria 28216|Betaproteobacteria S Appr-1-p processing - - - - - - - - - - - - Macro k59_239651_4 1328029.S0A1I2_9CAUD 1.35e-22 93.2 4QB07@10239|Viruses,4QVI0@35237|dsDNA viruses no RNA stage,4QQSI@28883|Caudovirales,4QNMQ@10744|Podoviridae 10744|Podoviridae S Protein of unknown function (DUF2493) - - - - - - - - - - - - - k59_568171_2 1121324.CLIT_8c00800 4.35e-28 117.0 COG4626@1|root,COG4626@2|Bacteria,1TPU1@1239|Firmicutes,248RI@186801|Clostridia,25TIP@186804|Peptostreptococcaceae 186801|Clostridia S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_82236_6 648757.Rvan_3136 4.32e-26 105.0 COG4186@1|root,COG4186@2|Bacteria,1RD94@1224|Proteobacteria,2U7MY@28211|Alphaproteobacteria,3N946@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria S Phosphoesterase or phosphohydrolase - - - - - - - - - - - - Metallophos,Metallophos_2 k59_553837_1 1379711.S5SYC9_9CIRC 7.16e-12 65.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_635885_1 411467.BACCAP_02633 5.84e-25 105.0 2DPIQ@1|root,3328X@2|Bacteria,1VFYC@1239|Firmicutes,25PC8@186801|Clostridia,26C3X@186813|unclassified Clostridiales 186801|Clostridia - - - - - - - - - - - - - - - k59_512885_2 410359.Pcal_1351 2.21e-07 55.5 arCOG05626@1|root,arCOG05626@2157|Archaea 2157|Archaea - - - - - - - - - - - - - - - k59_266759_1 529507.PMI3029 2.37e-45 161.0 COG0338@1|root,COG0338@2|Bacteria,1P85S@1224|Proteobacteria,1RMNW@1236|Gammaproteobacteria,3Z2IS@583|Proteus 1236|Gammaproteobacteria H D12 class N6 adenine-specific DNA methyltransferase dam GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006281,GO:0006298,GO:0006304,GO:0006305,GO:0006306,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007049,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009007,GO:0009008,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0022402,GO:0032259,GO:0032775,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043412,GO:0043414,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044728,GO:0044786,GO:0044787,GO:0046483,GO:0048037,GO:0050662,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901576,GO:1901681,GO:1902292,GO:1902328,GO:1904047 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 k59_266759_8 243230.DR_1889 2.18e-06 53.9 COG2389@1|root,COG2389@2|Bacteria,1WJUN@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S metal-binding protein (DUF2227) - - - - - - - - - - - - DUF2227 k59_267211_1 142661.REP_CACV 1.82e-24 107.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_246802_1 186617.M9M8L2_9VIRU 2.57e-34 139.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_372447_1 1234888.K0A2J2_9VIRU 9.32e-58 197.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_167578_1 1463920.JOGB01000001_gene3290 0.000911 48.1 COG0367@1|root,COG0367@2|Bacteria,2GJIM@201174|Actinobacteria 201174|Actinobacteria E asparagine synthase - - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 k59_598066_1 671143.DAMO_1309 0.000126 45.8 COG1943@1|root,COG1943@2|Bacteria,2NRRG@2323|unclassified Bacteria 2|Bacteria L Transposase IS200 like isplu5A - - ko:K07491 - - - - ko00000 - - - Y1_Tnp k59_476224_1 263358.VAB18032_15090 6.66e-10 61.2 COG2199@1|root,COG3706@2|Bacteria,2IABQ@201174|Actinobacteria,4D9W3@85008|Micromonosporales 201174|Actinobacteria T response regulator - - - - - - - - - - - - GGDEF,Response_reg k59_476224_2 1048830.GUU_00372 1.02e-11 65.9 COG0180@1|root,COG0180@2|Bacteria,3WT2W@544448|Tenericutes 544448|Tenericutes J Tryptophanyl-tRNA synthetase trpS - 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b k59_557072_2 1502724.FF80_01372 1.41e-16 82.8 COG3773@1|root,COG3773@2|Bacteria,1MWX3@1224|Proteobacteria,2TT15@28211|Alphaproteobacteria,3N6W7@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria M Cell Wall Hydrolase sleB - - - - - - - - - - - Hydrolase_2 k59_393112_1 406818.XBJ1_2043 3.44e-101 316.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,1SMCU@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_3797_4 13035.Dacsa_1441 2.56e-58 211.0 COG1351@1|root,COG1372@1|root,COG1403@1|root,COG1351@2|Bacteria,COG1372@2|Bacteria,COG1403@2|Bacteria,1G1PU@1117|Cyanobacteria 1117|Cyanobacteria F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant thyX - 2.1.1.148 ko:K03465 ko00240,ko00670,ko01100,map00240,map00670,map01100 - R06613 RC00022,RC00332 ko00000,ko00001,ko01000 - - - HNH,Intein_splicing,Thy1 k59_516961_1 360104.CCC13826_0188 5.04e-37 132.0 COG0270@1|root,COG0270@2|Bacteria 2|Bacteria L DNA (cytosine-5-)-methyltransferase activity dcm - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_516961_4 657309.BXY_05780 1.34e-10 63.5 COG0582@1|root,COG0582@2|Bacteria,4NVIT@976|Bacteroidetes,2G080@200643|Bacteroidia,4AV97@815|Bacteroidaceae 976|Bacteroidetes L COG4974 Site-specific recombinase XerD - - - - - - - - - - - - Arm-DNA-bind_5,Phage_int_SAM_5,Phage_integrase k59_64902_1 649743.HMPREF0972_02580 2.76e-11 68.9 COG0640@1|root,COG0640@2|Bacteria 2|Bacteria K DNA-binding transcription factor activity - - - ko:K19505,ko:K21885 - - - - ko00000,ko03000 - - - Fic,Fic_N,HTH_36,RP-C k59_598082_1 1202962.KB907186_gene2923 0.000424 47.4 COG1961@1|root,COG1961@2|Bacteria,1RC1A@1224|Proteobacteria,1S2ZW@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Resolvase, N terminal domain - - - - - - - - - - - - Resolvase k59_105441_10 1120933.ATUY01000002_gene83 1.65e-12 69.7 COG0553@1|root,COG0553@2|Bacteria,2IC31@201174|Actinobacteria,4D420@85005|Actinomycetales 201174|Actinobacteria KL SNF2 family N-terminal domain protein - - - - - - - - - - - - SNF2_N k59_578075_2 1165094.RINTHH_3920 4.07e-69 223.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_86643_1 1618247.A0A0C5IMK7_9CIRC 9.21e-12 70.9 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_517498_1 1123504.JQKD01000021_gene5682 3.13e-69 229.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2VNHP@28216|Betaproteobacteria,4AC68@80864|Comamonadaceae 28216|Betaproteobacteria S Terminase - - - - - - - - - - - - Terminase_1 k59_496370_3 1283079.M1IDA0_9CAUD 2.34e-07 51.2 4QAZF@10239|Viruses,4QUTY@35237|dsDNA viruses no RNA stage,4QPH6@28883|Caudovirales 28883|Caudovirales S Protein of unknwon function (DUF3310) - - - - - - - - - - - - - k59_557504_1 1327977.S0A018_9CAUD 0.000576 51.6 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QNBD@10744|Podoviridae 10744|Podoviridae S outer membrane - - - - - - - - - - - - - k59_208041_4 319236.JCM19294_1799 3.88e-05 46.2 COG1319@1|root,COG4886@1|root,COG1319@2|Bacteria,COG4886@2|Bacteria,4PHVI@976|Bacteroidetes,1IG6U@117743|Flavobacteriia,3HKW5@363408|Nonlabens 976|Bacteroidetes C Parallel beta-helix repeats - - - - - - - - - - - - - k59_624241_3 1236689.MMALV_03220 2.67e-09 58.2 COG1601@1|root,COG3269@1|root,arCOG01640@2157|Archaea,arCOG01641@2157|Archaea,2XTVZ@28890|Euryarchaeota,3F2N9@33867|unclassified Euryarchaeota 28890|Euryarchaeota J eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA eif2b - - ko:K03238 ko03013,map03013 - - - ko00000,ko00001,ko01009,ko03012 - - - TRAM,eIF-5_eIF-2B k59_483049_2 335541.Swol_2167 3.73e-40 142.0 COG0330@1|root,COG0330@2|Bacteria,1UZJK@1239|Firmicutes,24IK1@186801|Clostridia 186801|Clostridia O SPFH domain Band 7 family - - - - - - - - - - - - Band_7 k59_647119_2 904293.HMPREF9176_1201 2.49e-42 150.0 COG0842@1|root,COG0842@2|Bacteria,1UYSF@1239|Firmicutes,4HEYE@91061|Bacilli 91061|Bacilli V ABC-type multidrug transport system, permease component - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane,ABC2_membrane_3 k59_28459_2 762983.HMPREF9444_01670 3.7e-07 53.9 COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,1RN65@1236|Gammaproteobacteria,1Y3QX@135624|Aeromonadales 135624|Aeromonadales K Belongs to the ParB family - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_108698_1 1327993.S0A180_9CAUD 3.41e-07 58.5 4QFF1@10239|Viruses,4QWNY@35237|dsDNA viruses no RNA stage,4QPE1@28883|Caudovirales,4QN4T@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_295668_1 105154.Q9MBU6_9VIRU 7.23e-38 146.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_151621_1 1486472.A0A068F3I8_9CAUD 5.76e-97 304.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QM52@10699|Siphoviridae 10699|Siphoviridae S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor - - - - - - - - - - - - - k59_397654_1 1051675.G0YQI0_9CAUD 6.39e-35 137.0 4QF3C@10239|Viruses,4QWIA@35237|dsDNA viruses no RNA stage,4QU4U@28883|Caudovirales,4QNNQ@10744|Podoviridae 10744|Podoviridae S host cell wall - - - - - - - - - - - - - k59_233658_1 1499968.TCA2_0647 1.84e-57 187.0 COG1351@1|root,COG1351@2|Bacteria,1TRHD@1239|Firmicutes,4HTFB@91061|Bacilli,26S56@186822|Paenibacillaceae 91061|Bacilli F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - 2.1.1.148 ko:K03465 ko00240,ko00670,ko01100,map00240,map00670,map01100 - R06613 RC00022,RC00332 ko00000,ko00001,ko01000 - - - Thy1 k59_233658_3 1435356.Y013_21445 1.57e-42 153.0 COG3583@1|root,COG3583@2|Bacteria,2H4RU@201174|Actinobacteria,4FU6Q@85025|Nocardiaceae 201174|Actinobacteria S G5 rpfB - - ko:K21688 - - - - ko00000 - - - DUF348,G5,Transglycosylas k59_48568_1 1265756.AWZW01000008_gene1118 4.92e-08 58.5 2AN8I@1|root,31D6K@2|Bacteria,1P458@1224|Proteobacteria,2UWQ2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_132554_1 1161939.A0A067XGX5_9CAUD 1.49e-07 56.2 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales,4QNBQ@10744|Podoviridae 10744|Podoviridae S HNH endonuclease - - - - - - - - - - - - - k59_173995_1 1336208.JADY01000006_gene611 4.49e-18 92.0 COG4695@1|root,COG4695@2|Bacteria,1MUP5@1224|Proteobacteria,2TT33@28211|Alphaproteobacteria 28211|Alphaproteobacteria S portal protein - - - - - - - - - - - - Phage_portal k59_544420_1 1234888.K0A2J2_9VIRU 4.09e-49 173.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_179451_1 1408473.JHXO01000001_gene2330 3.37e-42 154.0 COG0008@1|root,COG0008@2|Bacteria,4NEED@976|Bacteroidetes,2FN2D@200643|Bacteroidia 976|Bacteroidetes J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX - 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - - tRNA-synt_1c k59_359982_1 1177928.TH2_05208 1.71e-25 118.0 COG4733@1|root,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria,2TV2W@28211|Alphaproteobacteria,2JV2T@204441|Rhodospirillales 204441|Rhodospirillales S COG4733 Phage-related protein, tail component - - - - - - - - - - - - Lambda_tail_I,Phage-tail_3 k59_359982_3 1430440.MGMSRv2_0660 3.14e-31 117.0 2C095@1|root,32VKM@2|Bacteria,1N5WT@1224|Proteobacteria,2VFY0@28211|Alphaproteobacteria,2JWAS@204441|Rhodospirillales 1224|Proteobacteria S Evidence 4 Homologs of previously reported genes of - - - - - - - - - - - - DUF1833 k59_359982_5 1123401.JHYQ01000021_gene1024 6.28e-15 82.8 COG0741@1|root,COG0741@2|Bacteria 2|Bacteria M lytic transglycosylase activity - - - - - - - - - - - - LysM,SLT k59_238591_3 105154.Q9MBU6_9VIRU 4.86e-134 403.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_588282_4 1408437.JNJN01000045_gene599 4e-09 62.4 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,25VCN@186806|Eubacteriaceae 186801|Clostridia L SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,SNF2_N,SNF2_assoc,SWIM k59_320846_2 1123020.AUIE01000007_gene3228 1.91e-46 162.0 2C89E@1|root,33QWA@2|Bacteria,1RDPC@1224|Proteobacteria,1SKAK@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_448656_1 575540.Isop_2443 1.66e-29 120.0 COG1061@1|root,COG1061@2|Bacteria,2J0ES@203682|Planctomycetes 203682|Planctomycetes L COGs COG1061 DNA or RNA helicase of superfamily II - - - ko:K19789 - - - - ko00000,ko03400 - - - Helicase_C,ResIII k59_505918_2 1147139.A0A0A6Z582_9CAUD 2.58e-13 70.5 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales,4QNBQ@10744|Podoviridae 10744|Podoviridae S HNH endonuclease - - - - - - - - - - - - - k59_424565_2 655812.HMPREF0061_0053 6.55e-09 63.9 COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,4HARA@91061|Bacilli,27DTX@186827|Aerococcaceae 91061|Bacilli D Belongs to the 'phage' integrase family. XerC subfamily xerC - - ko:K03733,ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase k59_531742_1 979556.MTES_3251 3.12e-08 52.8 arCOG05626@1|root,2Z9D9@2|Bacteria,2IIAB@201174|Actinobacteria,4FS1R@85023|Microbacteriaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_531742_2 1556290.A0A0A0RQE6_9CAUD 9.31e-55 179.0 4QAUS@10239|Viruses,4QQ2S@28883|Caudovirales,4QKRA@10699|Siphoviridae 10699|Siphoviridae S flavin adenine dinucleotide binding - - - - - - - - - - - - - k59_369651_1 942016.E9NIF8_9CAUD 5.21e-52 176.0 4QAR1@10239|Viruses,4QUNA@35237|dsDNA viruses no RNA stage,4QPJE@28883|Caudovirales,4QNDS@10744|Podoviridae 10744|Podoviridae S ATPase activity - - - - - - - - - - - - - k59_41564_1 1235799.C818_04197 1.86e-25 109.0 COG2887@1|root,COG2887@2|Bacteria,1TPIC@1239|Firmicutes,247TB@186801|Clostridia,27IAF@186928|unclassified Lachnospiraceae 186801|Clostridia L Protein of unknown function (DUF2800) - - - - - - - - - - - - DUF2800 k59_328921_2 61647.LG71_06515 1.61e-71 229.0 COG1475@1|root,COG1475@2|Bacteria,1R5VN@1224|Proteobacteria,1RZ7C@1236|Gammaproteobacteria 1236|Gammaproteobacteria K ParB-like nuclease domain ybdM - - - - - - - - - - - ParBc k59_328921_3 1157943.KB892705_gene2039 1.29e-125 377.0 COG3969@1|root,COG3969@2|Bacteria,2H4MT@201174|Actinobacteria 201174|Actinobacteria S Phosphoadenosine phosphosulfate reductase family - - - - - - - - - - - - PAPS_reduct k59_164844_1 1215114.BBIU01000011_gene1684 3.73e-28 107.0 2DSAB@1|root,33F8C@2|Bacteria 2|Bacteria S Protein of unknown function (DUF3168) - - - - - - - - - - - - DUF3168 k59_164844_2 243924.LT42_06420 1.07e-07 56.2 2B2IU@1|root,31V3Y@2|Bacteria,1QSZG@1224|Proteobacteria,1SSIH@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_164844_4 1150626.PHAMO_340052 1.26e-05 52.0 2CK39@1|root,32SBG@2|Bacteria,1Q39J@1224|Proteobacteria,2VA7Q@28211|Alphaproteobacteria,2JX2Y@204441|Rhodospirillales 204441|Rhodospirillales S Phage gp6-like head-tail connector protein - - - - - - - - - - - - Phage_connect_1 k59_144391_1 1353529.M899_2309 4e-06 51.6 COG2911@1|root,COG3209@1|root,COG2911@2|Bacteria,COG3209@2|Bacteria,1QY1R@1224|Proteobacteria,43C93@68525|delta/epsilon subdivisions,2MUT2@213481|Bdellovibrionales,2X7JI@28221|Deltaproteobacteria 213481|Bdellovibrionales M cell wall surface anchor family protein - - - - - - - - - - - - Peptidase_S74 k59_123757_1 1618251.A0A0C5I2L8_9CIRC 1.05e-18 92.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_493171_2 1618248.A0A0C5IB82_9CIRC 3.48e-91 280.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_575241_1 1498011.A0A096XUY1_9CAUD 7.3e-11 63.5 4QHBE@10239|Viruses,4QT2W@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_575241_2 1211579.PP4_02980 1.28e-07 58.5 COG1351@1|root,COG1351@2|Bacteria,1R6TS@1224|Proteobacteria,1S3UM@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant thyX - 2.1.1.148 ko:K03465 ko00240,ko00670,ko01100,map00240,map00670,map01100 - R06613 RC00022,RC00332 ko00000,ko00001,ko01000 - - - Thy1 k59_1091_1 1288963.ADIS_1093 7.23e-08 60.5 COG4974@1|root,COG4974@2|Bacteria,4NGE1@976|Bacteroidetes,47KKB@768503|Cytophagia 976|Bacteroidetes L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_int_SAM_4,Phage_integrase k59_616344_4 1392487.JIAD01000001_gene537 2.3e-06 51.2 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,25VE1@186806|Eubacteriaceae 186801|Clostridia KL SNF2 family N-terminal domain - - - - - - - - - - - - SNF2_N k59_476338_6 1394178.AWOO02000005_gene3597 6.96e-14 80.5 COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4EFIG@85012|Streptosporangiales 201174|Actinobacteria S ATPase family associated with various cellular activities (AAA) moxR2 - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 k59_351780_1 880073.Calab_0118 5.89e-05 55.8 COG2911@1|root,COG4733@1|root,COG2911@2|Bacteria,COG4733@2|Bacteria 2|Bacteria S cellulase activity - - 3.2.1.89 ko:K01224,ko:K20276 ko02024,map02024 - - - ko00000,ko00001,ko01000 - - - DctA-YdbH,Laminin_G_3 k59_310639_1 883081.HMPREF9698_01109 7.53e-16 82.8 COG5283@1|root,COG5412@1|root,COG5283@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,4HAFE@91061|Bacilli,27GNM@186828|Carnobacteriaceae 91061|Bacilli S Phage tail tape measure protein - - - - - - - - - - - - Peptidase_M23,PhageMin_Tail,SLT k59_167760_1 1556290.A0A0A0RSX5_9CAUD 1.1e-78 243.0 4QCAU@10239|Viruses,4QPJ6@28883|Caudovirales,4QKZJ@10699|Siphoviridae 10699|Siphoviridae S Pfam:GP88 - - - - - - - - - - - - - k59_250208_1 1234888.K0A2J2_9VIRU 1.34e-76 247.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_372610_4 1618242.A0A0C5IBR9_9CIRC 1.72e-37 142.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_393272_1 574376.BAMA_18490 8.81e-36 138.0 COG1674@1|root,COG1674@2|Bacteria,1V17G@1239|Firmicutes,4HD1E@91061|Bacilli,1ZDR7@1386|Bacillus 91061|Bacilli D FtsK/SpoIIIE family - - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_SpoIIIE k59_310650_1 994601.G9BW80_9CAUD 6.71e-23 95.9 4QCUC@10239|Viruses,4QY13@35237|dsDNA viruses no RNA stage,4QQ7E@28883|Caudovirales,4QNMG@10744|Podoviridae 10744|Podoviridae S nucleic acid binding - - - - - - - - - - - - - k59_105343_3 1121937.AUHJ01000007_gene1928 6.32e-36 126.0 2CJKM@1|root,314EI@2|Bacteria,1N8C9@1224|Proteobacteria,1SGI2@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_619195_8 67275.JOAP01000007_gene4300 5.13e-10 58.5 2CC1Y@1|root,32RUK@2|Bacteria,2IQ4Q@201174|Actinobacteria 201174|Actinobacteria K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA whmD - - ko:K18955 - - - - ko00000,ko03000 - - - Whib k59_228853_1 1120792.JAFV01000001_gene3544 1.46e-21 96.7 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2TSDW@28211|Alphaproteobacteria,36Z9P@31993|Methylocystaceae 28211|Alphaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_86717_2 1193128.A200_03694 2.8e-14 72.8 COG1388@1|root,COG3757@1|root,COG1388@2|Bacteria,COG3757@2|Bacteria 2|Bacteria M lysozyme activity - - 3.5.1.28 ko:K01447,ko:K01448,ko:K07273 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - CW_7,Glyco_hydro_25,LysM k59_210908_2 877240.E1AC06_9CAUD 2.06e-15 79.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_172412_3 1123321.KB905834_gene406 1.94e-29 128.0 COG3740@1|root,COG3740@2|Bacteria,2II2M@201174|Actinobacteria 201174|Actinobacteria S Phage prohead protease, HK97 family - - - - - - - - - - - - - k59_499546_1 69328.PVLB_04360 1.65e-08 60.1 COG3209@1|root,COG3209@2|Bacteria,1QVEQ@1224|Proteobacteria,1SGCM@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Chaperone of endosialidase - - - - - - - - - - - - Peptidase_S74 k59_232348_1 1173709.M3VMK9_9CIRC 5.79e-37 133.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_150842_3 1160718.SU9_10404 3.47e-08 58.5 COG0270@1|root,COG0270@2|Bacteria,2I8R8@201174|Actinobacteria 201174|Actinobacteria H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_274275_1 691965.D4P7D6_9CAUD 6.12e-46 164.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_482666_1 1132026.I6NQU5_9CAUD 3.06e-20 91.3 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_459880_1 1385658.U5KPZ6_9VIRU 4.96e-19 88.6 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_500087_2 1122175.ATXU01000009_gene1778 4.88e-15 75.9 COG4695@1|root,COG4695@2|Bacteria,2IE2H@201174|Actinobacteria,4FQ4F@85023|Microbacteriaceae 201174|Actinobacteria S Phage portal protein - - - - - - - - - - - - Phage_portal k59_543309_1 279383.Q5DN81_9CAUD 8.87e-64 212.0 4QBA2@10239|Viruses,4QV98@35237|dsDNA viruses no RNA stage,4QPPI@28883|Caudovirales,4QM0B@10699|Siphoviridae 10699|Siphoviridae S Thymidylate synthase - GO:0003674,GO:0003824,GO:0004799,GO:0008150,GO:0008152,GO:0008168,GO:0016740,GO:0016741,GO:0032259,GO:0042083 - - - - - - - - - - - k59_543309_4 1133022.I6NPA3_9CAUD 6.72e-37 144.0 4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_623970_1 658187.LDG_6143 1.62e-14 80.5 COG0467@1|root,COG1119@1|root,COG0467@2|Bacteria,COG1119@2|Bacteria 2|Bacteria P ATPase activity - - - ko:K03546,ko:K06919,ko:K07452,ko:K08482,ko:K09384,ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko01000,ko02042,ko02048,ko03400 - - - AAA_11,AAA_12,AAA_25,DUF4011 k59_215430_1 1000569.HMPREF1040_0205 3.34e-20 100.0 COG5545@1|root,COG5545@2|Bacteria,1TQNX@1239|Firmicutes,4H3CH@909932|Negativicutes 909932|Negativicutes S Virulence-associated protein E - - - - - - - - - - - - VirE k59_382374_1 105154.Q9MBU3_9VIRU 6.32e-06 51.6 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_112002_2 691965.D4P7D6_9CAUD 1.29e-134 412.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_279062_2 349123.Lreu23DRAFT_3114 7.62e-06 51.6 2CWXD@1|root,32T0J@2|Bacteria,1VJPE@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - k59_319614_1 1121952.ATXT01000007_gene1114 5.76e-06 53.5 COG4695@1|root,COG4695@2|Bacteria,2IJHD@201174|Actinobacteria,4FQ46@85023|Microbacteriaceae 201174|Actinobacteria S Portal protein - - - - - - - - - - - - Phage_portal k59_319622_2 1618248.A0A0C5IB82_9CIRC 3.25e-57 187.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_447114_1 1343740.M271_23415 9.98e-09 60.1 2B5ZH@1|root,31YVR@2|Bacteria,2IPSG@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_344790_1 1234888.K0A2J2_9VIRU 8.72e-59 201.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_382427_1 903818.KI912268_gene1318 0.000998 42.7 COG0702@1|root,COG0702@2|Bacteria,3Y7DF@57723|Acidobacteria 57723|Acidobacteria GM Protein of unknown function (DUF2867) - - - - - - - - - - - - DUF2867,NAD_binding_10 k59_382427_3 796620.VIBC2010_02331 6.04e-58 195.0 COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,1RMCP@1236|Gammaproteobacteria,1Y0HD@135623|Vibrionales 135623|Vibrionales F Dihydroorotate dehydrogenase - - 1.3.5.2 ko:K00254 ko00240,ko01100,map00240,map01100 M00051 R01868 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh k59_98913_1 56107.Cylst_3541 1.24e-16 79.3 COG0338@1|root,COG0338@2|Bacteria,1G6KT@1117|Cyanobacteria,1HRAN@1161|Nostocales 1117|Cyanobacteria L PFAM D12 class N6 adenine-specific DNA methyltransferase - - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 k59_155895_1 49964.Q94MS1_9CAUD 6.29e-97 293.0 4QB4H@10239|Viruses,4QYQI@35237|dsDNA viruses no RNA stage,4QUAR@28883|Caudovirales,4QNUV@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_112056_1 77856.CAPSD_BFDV 3.72e-40 143.0 4QC68@10239|Viruses,4QUKE@29258|ssDNA viruses 10239|Viruses S viral capsid assembly - - - - - - - - - - - - - k59_74424_1 186617.M9M8L2_9VIRU 6.06e-88 280.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_423803_1 1141140.K4FCD2_9CAUD 4.84e-05 53.9 4QAQ9@10239|Viruses,4QUYQ@35237|dsDNA viruses no RNA stage,4QPTV@28883|Caudovirales,4QKRS@10699|Siphoviridae 10699|Siphoviridae S Putative phage tail protein - GO:0005575,GO:0008150,GO:0016032,GO:0018995,GO:0019012,GO:0019058,GO:0019062,GO:0022610,GO:0030430,GO:0033643,GO:0033646,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044403,GO:0044406,GO:0044419,GO:0044650,GO:0051704 - - - - - - - - - - - k59_587713_2 469378.Ccur_01830 9.93e-38 139.0 COG1104@1|root,COG1104@2|Bacteria,2GKUT@201174|Actinobacteria,4CUWW@84998|Coriobacteriia 84998|Coriobacteriia E aminotransferase class V - - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 k59_654910_2 327277.JHAL01000002_gene535 1.2e-27 108.0 COG0863@1|root,COG2521@1|root,COG0863@2|Bacteria,COG2521@2|Bacteria,2IM4X@201174|Actinobacteria 201174|Actinobacteria L DNA methylase - - - - - - - - - - - - N6_N4_Mtase k59_74958_1 1463936.JOJI01000112_gene3307 1.44e-19 88.2 COG1403@1|root,COG1403@2|Bacteria,2GYWG@201174|Actinobacteria 201174|Actinobacteria L HNH endonuclease - - - - - - - - - - - - HNH,HNH_3 k59_551221_1 759938.F5BSB4_9CIRC 2.58e-20 92.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_634164_2 717606.PaecuDRAFT_2133 2.26e-05 50.8 COG4675@1|root,COG4675@2|Bacteria,1V943@1239|Firmicutes,4HJCC@91061|Bacilli,26YNV@186822|Paenibacillaceae 91061|Bacilli S Phage Tail Collar Domain - - - - - - - - - - - - Collar k59_570974_1 1379711.S5TNC7_9CIRC 7.61e-13 75.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_509882_1 1262528.L7TI46_9VIRU 3.28e-14 71.6 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage 10239|Viruses S HNH endonuclease - - - - - - - - - - - - - k59_509882_2 421052.F945_02819 2.43e-31 118.0 COG0302@1|root,COG0302@2|Bacteria,1MY3N@1224|Proteobacteria,1RMQM@1236|Gammaproteobacteria,3NKQ6@468|Moraxellaceae 1236|Gammaproteobacteria H GTP cyclohydrolase - - 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydroI k59_570981_2 1244869.H261_03473 1.43e-58 185.0 COG2131@1|root,COG2131@2|Bacteria,1RD1P@1224|Proteobacteria,2UD7X@28211|Alphaproteobacteria,2JUU2@204441|Rhodospirillales 204441|Rhodospirillales F COG2131 Deoxycytidylate deaminase - - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 k59_388957_1 589924.Ferp_0521 1.33e-08 61.2 COG0501@1|root,COG3864@1|root,arCOG01334@2157|Archaea,arCOG06980@2157|Archaea,2Y3NI@28890|Euryarchaeota 28890|Euryarchaeota O Putative metallopeptidase domain - - - - - - - - - - - - DUF2201,DUF2201_N k59_143235_2 1144932.ATTF01000015_gene1210 2.16e-22 94.7 COG0817@1|root,COG0817@2|Bacteria,1NDKU@1224|Proteobacteria 1224|Proteobacteria L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group ruvC - 3.1.22.4 ko:K01159 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - - k59_325927_2 1692242.A0A0K1RL37_9CIRC 6.96e-40 144.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_19809_1 105154.Q9MBU6_9VIRU 4.27e-40 149.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_388978_1 414996.IL38_17240 1.71e-30 122.0 COG0124@1|root,COG0124@2|Bacteria,2GIYJ@201174|Actinobacteria,409ZU@622450|Actinopolysporales 201174|Actinobacteria J Histidyl-tRNA synthetase hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_His k59_284408_1 1605.Lani381_0869 2.2e-19 99.4 COG4487@1|root,COG5283@1|root,COG4487@2|Bacteria,COG5283@2|Bacteria,1UHQM@1239|Firmicutes,4ISAG@91061|Bacilli,3F4HB@33958|Lactobacillaceae 91061|Bacilli S Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_429612_1 1041147.AUFB01000014_gene329 5.03e-19 84.3 2CXZV@1|root,32T32@2|Bacteria,1N4R9@1224|Proteobacteria,2UM96@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_266314_1 420324.KI911999_gene8048 4.15e-97 297.0 COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,2TQPK@28211|Alphaproteobacteria,1JR9H@119045|Methylobacteriaceae 28211|Alphaproteobacteria J Belongs to the class-I aminoacyl-tRNA synthetase family leuS - 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 k59_617309_1 1173762.S4TP28_9CAUD 1.25e-66 224.0 4QGA5@10239|Viruses,4QURD@35237|dsDNA viruses no RNA stage,4QT9N@28883|Caudovirales,4QP47@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_411914_1 880070.Cycma_3143 3.21e-22 100.0 COG0358@1|root,COG0358@2|Bacteria,4NEFU@976|Bacteroidetes,47Q6Q@768503|Cytophagia 976|Bacteroidetes L COG NOG08810 non supervised orthologous group - - - - - - - - - - - - - k59_22188_1 691965.D4P7I3_9CAUD 0.0 1156.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_84042_1 1033739.CAEU01000065_gene108 0.000854 47.8 COG4695@1|root,COG4695@2|Bacteria,1TP8B@1239|Firmicutes,4HHWD@91061|Bacilli 91061|Bacilli S portal protein - - - - - - - - - - - - Phage_portal k59_309005_4 391596.PBAL39_13060 8.35e-07 53.1 2DRDZ@1|root,33BC3@2|Bacteria,4NZJ0@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - k59_309005_6 657309.BXY_25280 1.24e-16 81.6 COG0270@1|root,COG0270@2|Bacteria,4NJPP@976|Bacteroidetes,2FKYT@200643|Bacteroidia,4AQVC@815|Bacteroidaceae 976|Bacteroidetes L C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_514995_1 742733.HMPREF9469_05036 2.59e-54 175.0 2AIHK@1|root,318ZG@2|Bacteria,1V7P0@1239|Firmicutes,24KNU@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_309007_1 500635.MITSMUL_03105 5.47e-16 82.0 COG0756@1|root,COG0756@2|Bacteria,1U4S1@1239|Firmicutes,4H64B@909932|Negativicutes 909932|Negativicutes F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA - - 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase k59_268554_3 1178825.ALIH01000004_gene2985 0.000214 53.9 COG1470@1|root,COG2911@1|root,COG3209@1|root,COG3291@1|root,COG5184@1|root,COG1470@2|Bacteria,COG2911@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG5184@2|Bacteria,4NDZC@976|Bacteroidetes,1IJ8A@117743|Flavobacteriia 976|Bacteroidetes G Pkd domain containing protein - - - - - - - - - - - - CHU_C,DUF11,Gal_Lectin,HYR,Laminin_G_3,PKD,SprB,TSP_3 k59_535336_1 1609634.A0A0C5ANA6_9VIRU 1.47e-10 65.1 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_268565_1 1455075.W6PUJ9_9CAUD 9.79e-28 107.0 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales,4QNBQ@10744|Podoviridae 10744|Podoviridae S HNH endonuclease - - - - - - - - - - - - - k59_596261_1 1589297.A0A0B5H2N7_9CAUD 8.64e-18 90.5 4QAXA@10239|Viruses,4QQ1A@28883|Caudovirales,4QNU7@10744|Podoviridae 10744|Podoviridae S metallopeptidase activity - - - - - - - - - - - - - k59_576136_1 1357400.HMPREF2086_01502 1.95e-83 259.0 COG0863@1|root,COG0863@2|Bacteria,1R7RV@1224|Proteobacteria,42NFT@68525|delta/epsilon subdivisions 1224|Proteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.113 ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_576136_2 411473.RUMCAL_00286 4.11e-63 204.0 COG0270@1|root,COG0270@2|Bacteria,1VSZI@1239|Firmicutes,24YBG@186801|Clostridia 186801|Clostridia L C-5 cytosine-specific DNA methylase - - - - - - - - - - - - DNA_methylase k59_350251_6 694429.Pyrfu_0137 1.2e-05 50.4 COG1573@1|root,arCOG00905@2157|Archaea,2XQ7T@28889|Crenarchaeota 28889|Crenarchaeota L TIGRFAM phage SPO1 DNA polymerase-related protein - GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k59_535353_1 1540097.A0A0A0YW88_9CAUD 3.2e-24 102.0 4QGA5@10239|Viruses,4QT9N@28883|Caudovirales,4QP47@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_535353_2 1051675.G0YQG3_9CAUD 7.6e-45 158.0 4QEG2@10239|Viruses,4QVSD@35237|dsDNA viruses no RNA stage,4QRJ9@28883|Caudovirales,4QP0R@10744|Podoviridae 10744|Podoviridae S exonuclease activity - - - - - - - - - - - - - k59_350566_2 653045.Strvi_0013 6.51e-15 78.2 2C1BF@1|root,33VHU@2|Bacteria,2IE0H@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_268874_4 1406840.Q763_17125 9.5e-50 170.0 COG0740@1|root,COG0740@2|Bacteria,4NNEB@976|Bacteroidetes,1IN9D@117743|Flavobacteriia,2NYMF@237|Flavobacterium 976|Bacteroidetes OU Clp protease - - 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease k59_227437_2 755731.Clo1100_1151 1.92e-09 60.5 COG1694@1|root,COG1694@2|Bacteria 2|Bacteria FG Mazg nucleotide pyrophosphohydrolase - - - - - - - - - - - - - k59_311577_3 469383.Cwoe_4526 1.32e-53 199.0 COG1061@1|root,COG1061@2|Bacteria,2GIU5@201174|Actinobacteria,4CPQY@84995|Rubrobacteria 84995|Rubrobacteria L type III restriction enzyme, res subunit - - - - - - - - - - - - Helicase_C,ResIII k59_641868_2 548479.HMPREF0573_11392 3.89e-28 113.0 COG4695@1|root,COG4695@2|Bacteria,2IE2H@201174|Actinobacteria,4D5XF@85005|Actinomycetales 201174|Actinobacteria S Phage portal protein - - - - - - - - - - - - Phage_portal k59_478013_2 1122201.AUAZ01000017_gene2947 3.08e-18 85.5 COG0749@1|root,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,465DD@72275|Alteromonadaceae 1236|Gammaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity - - - - - - - - - - - - DNA_pol_A k59_352920_2 391008.Smal_2505 1.8e-11 63.2 COG1403@1|root,COG1403@2|Bacteria,1Q1AJ@1224|Proteobacteria,1TEH4@1236|Gammaproteobacteria,1XBNU@135614|Xanthomonadales 135614|Xanthomonadales L HNH endonuclease - - - ko:K07451 - - - - ko00000,ko01000,ko02048 - - - HNH_3 k59_497522_1 1234888.K0A2J2_9VIRU 1.38e-56 194.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_579244_1 1089121.G8I4T8_9CAUD 4.03e-32 117.0 4QASD@10239|Viruses,4QZ7D@35237|dsDNA viruses no RNA stage,4QTMZ@28883|Caudovirales,4QM9B@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_579244_2 202955.BBND01000008_gene2154 5.79e-08 55.8 COG1403@1|root,COG1403@2|Bacteria,1Q88B@1224|Proteobacteria,1RTRW@1236|Gammaproteobacteria,3NQAV@468|Moraxellaceae 1236|Gammaproteobacteria V HNH endonuclease - - - - - - - - - - - - HNH k59_189740_2 78345.BMERY_1861 2.3e-39 146.0 COG1134@1|root,COG1682@1|root,COG1134@2|Bacteria,COG1682@2|Bacteria,2GIVF@201174|Actinobacteria,4CZ1B@85004|Bifidobacteriales 201174|Actinobacteria GM ABC transporter, ATP-binding protein - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,Wzt_C k59_599669_1 1220714.L7TK38_9CAUD 1.02e-20 94.7 4QFED@10239|Viruses,4R072@35237|dsDNA viruses no RNA stage,4QPEH@28883|Caudovirales 28883|Caudovirales S tRNA modification - - - - - - - - - - - - - k59_230092_1 1111121.HMPREF1247_0229 2.2e-53 186.0 COG0154@1|root,COG0154@2|Bacteria,2GJK5@201174|Actinobacteria,4CUA0@84998|Coriobacteriia 84998|Coriobacteriia J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase k59_87956_4 1410631.JHWZ01000006_gene316 3.95e-21 87.8 COG0853@1|root,COG0853@2|Bacteria,1V6NQ@1239|Firmicutes,24JVN@186801|Clostridia,27MXS@186928|unclassified Lachnospiraceae 186801|Clostridia H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine panD - 4.1.1.11 ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R00489 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Asp_decarbox k59_87956_5 118161.KB235922_gene3805 5.77e-08 58.5 COG0189@1|root,COG0189@2|Bacteria,1GE84@1117|Cyanobacteria,3VM8I@52604|Pleurocapsales 1117|Cyanobacteria HJ ligase activity - - - - - - - - - - - - - k59_128386_2 1692244.A0A0K1RLR5_9CIRC 2.46e-93 283.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_87959_1 1458697.W6EKG4_9CAUD 7.5e-07 56.2 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QM2K@10699|Siphoviridae 10699|Siphoviridae S Phage Tail Collar Domain - - - - - - - - - - - - - k59_292357_1 1123321.KB905822_gene3894 3.54e-14 78.2 2DWF6@1|root,3400H@2|Bacteria,2IBDX@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_499895_1 319236.JCM19294_2093 8.85e-91 286.0 COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,1HXHB@117743|Flavobacteriia,3HKGC@363408|Nonlabens 976|Bacteroidetes F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdA - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_lgC,Ribonuc_red_lgN k59_482362_2 1238450.VIBNISOn1_1560031 4.17e-19 83.6 2BVTZ@1|root,31ABS@2|Bacteria,1R1C7@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_459698_2 1692249.A0A0K1RL40_9CIRC 3.94e-44 158.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_337933_1 1041159.AZUW01000018_gene765 0.000807 48.5 COG1475@1|root,COG1475@2|Bacteria,1QAFW@1224|Proteobacteria,2U1MZ@28211|Alphaproteobacteria,4BB0X@82115|Rhizobiaceae 28211|Alphaproteobacteria K Belongs to the ParB family - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc,RepB k59_522725_1 186617.M9M8L2_9VIRU 1.13e-21 100.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_232687_2 713586.KB900536_gene1134 1.17e-12 72.4 COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,1RY1X@1236|Gammaproteobacteria,1WW3S@135613|Chromatiales 135613|Chromatiales S associated with various cellular activities - - - - - - - - - - - - AAA,AAA_5 k59_418103_2 29875.EHK22908 1.8e-05 58.2 2CNC5@1|root,2QV54@2759|Eukaryota,39S8X@33154|Opisthokonta,3NZKK@4751|Fungi,3QRQ4@4890|Ascomycota,214Z4@147550|Sordariomycetes,3TUCQ@5125|Hypocreales 4751|Fungi O Pectate lyase superfamily protein - - 3.2.1.58 ko:K01210 ko00500,map00500 - R00308,R03115 RC00467 ko00000,ko00001,ko01000 - - - Pectate_lyase_3 k59_499896_3 42099.EPrPV00000023206 4.11e-09 63.9 2EIIE@1|root,2SNY1@2759|Eukaryota 2759|Eukaryota - - - - - - - - - - - - - - HTH_OrfB_IS605,OrfB_Zn_ribbon k59_522749_1 573370.DMR_25050 1.84e-12 72.4 28W6R@1|root,2ZI7D@2|Bacteria,1N49N@1224|Proteobacteria,431A7@68525|delta/epsilon subdivisions,2WWPT@28221|Deltaproteobacteria,2M9A2@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_108421_2 1556290.A0A0A0RLF5_9CAUD 1.11e-70 228.0 4QCWQ@10239|Viruses,4QQZU@28883|Caudovirales,4QMRV@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_440845_1 1692253.A0A0K1RLM4_9CIRC 2.35e-14 77.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_131884_1 596153.Alide_1431 2.95e-68 224.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2VNHP@28216|Betaproteobacteria,4AC68@80864|Comamonadaceae 28216|Betaproteobacteria S Terminase - - - - - - - - - - - - Terminase_1 k59_543516_1 1609634.A0A0C5AFT2_9VIRU 7.93e-28 112.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_214182_2 1150398.JIBJ01000003_gene1825 9.19e-30 112.0 COG0741@1|root,COG0741@2|Bacteria 2|Bacteria M lytic transglycosylase activity - - - - - - - - - - - - SLT,Transglycosylas k59_236201_1 1234888.K0A2J2_9VIRU 2.62e-62 207.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_196197_1 1234888.K0A2J2_9VIRU 8.48e-100 311.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_214688_1 172088.AUGA01000082_gene6217 3.57e-49 169.0 COG3740@1|root,COG3740@2|Bacteria,1NBQ9@1224|Proteobacteria,2UK6T@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Caudovirus prohead serine protease - - - - - - - - - - - - Peptidase_S78 k59_445987_3 105422.BBPM01000058_gene4616 5.24e-71 239.0 COG1475@1|root,COG4422@1|root,COG1475@2|Bacteria,COG4422@2|Bacteria,2IAY7@201174|Actinobacteria,2NK47@228398|Streptacidiphilus 201174|Actinobacteria K DNA binding - - - - - - - - - - - - ParBc k59_586314_1 755732.Fluta_2952 1.79e-11 67.0 28HND@1|root,2Z7WP@2|Bacteria,4NMSD@976|Bacteroidetes,1I1C9@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_586314_2 1121896.JMLU01000038_gene1963 9.91e-16 89.7 COG5545@1|root,COG5545@2|Bacteria,4NG2W@976|Bacteroidetes,1HYGS@117743|Flavobacteriia,2NUAG@237|Flavobacterium 976|Bacteroidetes S Virulence-associated protein E - - - - - - - - - - - - DUF3874,VirE,VirE_N k59_97600_1 1123320.KB889698_gene9323 4.94e-08 60.1 COG2133@1|root,COG3055@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3055@2|Bacteria,COG3291@2|Bacteria 2|Bacteria S metallopeptidase activity - - 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 - R06200,R11307,R11308 - ko00000,ko00001,ko01000 - GH5,GH9 - Calx-beta,GSDH,Laminin_G_3,Malectin,PKD k59_586316_2 28229.ND2E_3441 2.67e-12 71.2 COG1196@1|root,COG1196@2|Bacteria,1NK8W@1224|Proteobacteria,1SGJD@1236|Gammaproteobacteria 1236|Gammaproteobacteria D DNA N-6-adenine-methyltransferase (Dam) - - - - - - - - - - - - Dam k59_214716_2 1141136.K4F9L2_9CAUD 8.5e-16 77.8 4QAIK@10239|Viruses,4QUPH@35237|dsDNA viruses no RNA stage,4QPEB@28883|Caudovirales,4QHXI@10662|Myoviridae 10662|Myoviridae S hydrolase activity - - - - - - - - - - - - - k59_196786_1 755178.Cyan10605_2313 6.84e-12 64.3 COG1403@1|root,COG1403@2|Bacteria,1G7VH@1117|Cyanobacteria 1117|Cyanobacteria L PFAM HNH endonuclease - - - ko:K07451 - - - - ko00000,ko01000,ko02048 - - - HNH,HNH_5 k59_464563_2 266265.Bxe_A3055 3.09e-09 61.6 29F88@1|root,3025X@2|Bacteria,1NBJS@1224|Proteobacteria,2VWHK@28216|Betaproteobacteria,1KB80@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_422553_2 411902.CLOBOL_04837 2.97e-40 147.0 COG0791@1|root,COG3772@1|root,COG0791@2|Bacteria,COG3772@2|Bacteria,1VG3D@1239|Firmicutes,25FTG@186801|Clostridia,223QR@1506553|Lachnoclostridium 186801|Clostridia M Phage lysozyme - - - - - - - - - - - - - k59_381623_2 411489.CLOL250_02031 4.64e-07 52.8 COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,36DTR@31979|Clostridiaceae 186801|Clostridia L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_136331_1 1732201.A0A0N9N7I3_9CIRC 1.19e-20 94.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_214727_2 417280.A1YZY4_9CAUD 3.48e-71 235.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QI9F@10662|Myoviridae 10662|Myoviridae S Type III restriction enzyme, res subunit - - - - - - - - - - - - - k59_115372_18 1327970.R9ZZD0_9CAUD 5.33e-68 214.0 4QEMB@10239|Viruses,4QVSG@35237|dsDNA viruses no RNA stage,4QQ55@28883|Caudovirales,4QNA8@10699|Siphoviridae 10699|Siphoviridae S Bacteriophage Lambda NinG protein - - - - - - - - - - - - - k59_115372_19 762982.HMPREF9442_01223 1.12e-95 294.0 COG0270@1|root,COG0270@2|Bacteria,4NJPP@976|Bacteroidetes,2FKYT@200643|Bacteroidia 976|Bacteroidetes H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_282183_1 903818.KI912268_gene2766 3.7e-06 53.5 COG1506@1|root,COG3291@1|root,COG1506@2|Bacteria,COG3291@2|Bacteria 2|Bacteria S metallopeptidase activity - - - ko:K06889 - - - - ko00000 - - - Abhydrolase_3,Peptidase_S9 k59_78537_1 76114.ebA7273 2.23e-64 207.0 28J67@1|root,2Z91Y@2|Bacteria,1R7RG@1224|Proteobacteria,2VRTM@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_264749_2 1210884.HG799466_gene12740 4.87e-15 78.2 2C9JF@1|root,32RPD@2|Bacteria 2|Bacteria S Erf family - - - - - - - - - - - - ERF k59_241434_1 691965.D4P7D3_9CAUD 4.35e-158 458.0 4QAYV@10239|Viruses,4QUZ7@35237|dsDNA viruses no RNA stage,4QPU3@28883|Caudovirales,4QKKX@10699|Siphoviridae 10699|Siphoviridae S Phage portal protein - - - - - - - - - - - - - k59_37312_1 691965.D4P7I3_9CAUD 1.87e-31 124.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_144009_1 1250006.JHZZ01000001_gene1559 4.95e-08 59.3 COG4675@1|root,COG4675@2|Bacteria,4NR3Y@976|Bacteroidetes,1INAY@117743|Flavobacteriia,3VXBV@52959|Polaribacter 976|Bacteroidetes S Phage Tail Collar Domain - - - - - - - - - - - - Collar k59_574803_1 498848.TaqDRAFT_3019 2.4e-08 53.1 28XPN@1|root,2ZJKF@2|Bacteria 2|Bacteria S Domain of unknown function (DUF1874) - - - - - - - - - - - - DUF1874 k59_636313_1 1111121.HMPREF1247_0772 4.42e-22 102.0 COG0305@1|root,COG0305@2|Bacteria,2GKXQ@201174|Actinobacteria,4CUUP@84998|Coriobacteriia 84998|Coriobacteriia L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_533642_1 1609634.A0A0C5AFT2_9VIRU 7.2e-34 128.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_226089_1 1120936.KB907208_gene1116 1.53e-39 147.0 2FA48@1|root,342D2@2|Bacteria,2H6VX@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_41439_1 1463900.JOIX01000006_gene741 3.33e-06 57.4 COG1783@1|root,COG1783@2|Bacteria,2I8SC@201174|Actinobacteria 201174|Actinobacteria S Terminase-like family - - - - - - - - - - - - Terminase_3,Terminase_6,Terminase_6C k59_554204_1 1444712.BN1013_00113 2.96e-231 654.0 COG0843@1|root,COG0843@2|Bacteria,2JFT7@204428|Chlamydiae 204428|Chlamydiae C Cytochrome C and Quinol oxidase polypeptide I cyoB - 1.10.3.10 ko:K02298 ko00190,ko01100,map00190,map01100 M00417 R11335 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.5 - - COX1 k59_144021_2 1589297.A0A0B5H2N3_9CAUD 1.14e-101 302.0 4QEMD@10239|Viruses,4QUGF@28883|Caudovirales,4QNXF@10744|Podoviridae 10744|Podoviridae S AAA domain - - - - - - - - - - - - - k59_226107_1 1283300.ATXB01000001_gene707 1.56e-109 348.0 COG4643@1|root,COG5519@1|root,COG4643@2|Bacteria,COG5519@2|Bacteria,1MW5H@1224|Proteobacteria,1RQ7H@1236|Gammaproteobacteria,1XGJ9@135618|Methylococcales 1236|Gammaproteobacteria L Domain of unknown function (DUF927) Z012_01240 - - ko:K06919 - - - - ko00000 - - - DUF927,Prim_Zn_Ribbon,Toprim_3 k59_102991_1 1234888.K0A2J2_9VIRU 1.39e-52 181.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_246786_2 186617.M9M8L2_9VIRU 2.48e-40 157.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_451731_1 388051.AUFE01000035_gene4020 3.2e-46 163.0 COG4653@1|root,COG4653@2|Bacteria 2|Bacteria G Phage capsid family - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_61879_2 1476876.JOJO01000002_gene6649 3.29e-122 374.0 COG5362@1|root,COG5362@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Terminase_6C k59_61879_3 1476876.JOJO01000002_gene6648 2.57e-94 299.0 2E3FN@1|root,32YEG@2|Bacteria 2|Bacteria S Phage portal protein, SPP1 Gp6-like - - - - - - - - - - - - Phage_prot_Gp6 k59_513369_1 1563661.A0A097PAJ8_9CAUD 7.05e-52 180.0 4QAR1@10239|Viruses,4QPJE@28883|Caudovirales,4QNDS@10744|Podoviridae 10744|Podoviridae S ATPase activity - - - - - - - - - - - - - k59_639009_13 865861.AZSU01000007_gene1124 1.27e-12 68.9 COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,24HF0@186801|Clostridia,36IFF@31979|Clostridiaceae 186801|Clostridia F Cytidine and deoxycytidylate deaminase zinc-binding region comEB - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 k59_618412_1 1176423.I6S776_9VIRU 6.31e-28 107.0 4QE7X@10239|Viruses,4QVF0@35237|dsDNA viruses no RNA stage 10239|Viruses S Cytidine and deoxycytidylate deaminase zinc-binding region - - - - - - - - - - - - - k59_412760_1 1204521.I6ZXZ4_9CAUD 2.88e-12 67.4 4QHBE@10239|Viruses,4QT2W@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_412760_2 857087.Metme_0048 1.24e-07 59.3 COG1351@1|root,COG1351@2|Bacteria,1R6TS@1224|Proteobacteria,1S3UM@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant thyX - 2.1.1.148 ko:K03465 ko00240,ko00670,ko01100,map00240,map00670,map01100 - R06613 RC00022,RC00332 ko00000,ko00001,ko01000 - - - Thy1 k59_269345_1 329381.D9ICQ3_9CAUD 1.08e-13 76.3 4QAKE@10239|Viruses,4QUP7@35237|dsDNA viruses no RNA stage,4QPCE@28883|Caudovirales,4QI56@10662|Myoviridae 10662|Myoviridae S nucleic acid binding - - - - - - - - - - - - - k59_309906_1 665956.HMPREF1032_00686 1.26e-33 134.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia,3WN92@541000|Ruminococcaceae 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_475451_1 1692253.A0A0K1RLM4_9CIRC 1.11e-41 157.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_516251_1 1429767.W6AQV5_9CAUD 2.53e-42 157.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_516251_2 1476391.X5KIN0_9CAUD 2.1e-15 76.6 4QEG2@10239|Viruses,4QVSD@35237|dsDNA viruses no RNA stage,4QRJ9@28883|Caudovirales,4QP0R@10744|Podoviridae 10744|Podoviridae S exonuclease activity - - - - - - - - - - - - - k59_249522_1 1382359.JIAL01000001_gene220 1.91e-29 120.0 COG0675@1|root,COG0675@2|Bacteria 2|Bacteria L Transposase, IS605 OrfB family insQ - - ko:K07496 - - - - ko00000 - - - HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon k59_64403_2 391600.ABRU01000008_gene2868 9.85e-13 68.6 2DMHT@1|root,32RN3@2|Bacteria,1N0KK@1224|Proteobacteria,2UCFK@28211|Alphaproteobacteria,2KJ8K@204458|Caulobacterales 204458|Caulobacterales J PEGA domain - - - - - - - - - - - - PEGA k59_26675_1 768671.ThimaDRAFT_2191 8.54e-29 110.0 COG0358@1|root,COG0358@2|Bacteria,1N364@1224|Proteobacteria,1SHYJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria L DNA primase - - - - - - - - - - - - - k59_416732_1 1120978.KB894079_gene668 1.06e-08 60.5 COG0847@1|root,COG1199@1|root,COG0847@2|Bacteria,COG1199@2|Bacteria,1TQHQ@1239|Firmicutes,4HB2Y@91061|Bacilli,27FUH@186828|Carnobacteriaceae 91061|Bacilli L helicase involved in DNA repair and perhaps also replication dinG GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901576,GO:1902494,GO:1990234 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - DEAD,Helicase_C_2,RNase_T,ResIII k59_293806_2 1408444.JHYC01000018_gene307 4.15e-42 151.0 COG0582@1|root,COG0582@2|Bacteria,1MWBN@1224|Proteobacteria,1RPD0@1236|Gammaproteobacteria,1JDMK@118969|Legionellales 118969|Legionellales L Phage integrase family - - - - - - - - - - - - Phage_integrase k59_559975_1 196162.Noca_3857 2.61e-18 88.2 COG3583@1|root,COG3583@2|Bacteria,2H4RU@201174|Actinobacteria,4DMZZ@85009|Propionibacteriales 201174|Actinobacteria M G5 rlpA - - ko:K21688 - - - - ko00000 - - - DUF348,G5,Transglycosylas k59_580593_1 717785.HYPMC_4253 3.31e-06 53.5 COG5281@1|root,COG5281@2|Bacteria,1MX2R@1224|Proteobacteria,2U3WK@28211|Alphaproteobacteria 28211|Alphaproteobacteria D tape measure protein - - - - - - - - - - - - - k59_273030_1 754331.AEME01000001_gene3872 1.46e-66 215.0 COG1475@1|root,COG1475@2|Bacteria,1R5VN@1224|Proteobacteria,1RZ7C@1236|Gammaproteobacteria,3XNY5@561|Escherichia 1236|Gammaproteobacteria K ParB-like nuclease domain ybdM - - - - - - - - - - - ParBc k59_129912_1 247633.GP2143_10887 4.32e-45 166.0 COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,1RMIV@1236|Gammaproteobacteria,1J5FI@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Peptidoglycan polymerase that is essential for cell division ftsW GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008360,GO:0009987,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032153,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051179,GO:0051234,GO:0051301,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505 - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE k59_129912_2 882.DVU_2504 1.48e-30 127.0 COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,42ME1@68525|delta/epsilon subdivisions,2WJNY@28221|Deltaproteobacteria,2M8I2@213115|Desulfovibrionales 28221|Deltaproteobacteria M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG - 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 - Glyco_tran_28_C,Glyco_transf_28 k59_68153_1 59538.XP_005973169.1 2.25e-64 214.0 COG0143@1|root,KOG0436@2759|Eukaryota,38HBR@33154|Opisthokonta,3B9FE@33208|Metazoa,3CXB5@33213|Bilateria,480WR@7711|Chordata,48YQN@7742|Vertebrata,3J8AY@40674|Mammalia,4J8KS@91561|Cetartiodactyla 33154|Opisthokonta J methionyl-tRNA synthetase 2, mitochondrial MSM1 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031974,GO:0032543,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140053,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1g k59_601364_3 1042163.BRLA_07p000010 3.77e-26 110.0 28KEB@1|root,3063N@2|Bacteria,1TZ4V@1239|Firmicutes,4I8BZ@91061|Bacilli,273D7@186822|Paenibacillaceae 91061|Bacilli - - - - - - - - - - - - - - - k59_501535_1 1234888.K0A2J2_9VIRU 2.91e-73 239.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_194755_1 384765.SIAM614_02716 0.000168 49.7 2EZ1Q@1|root,33S85@2|Bacteria,1NSWJ@1224|Proteobacteria,2UQSR@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Helix-turn-helix domain - - - - - - - - - - - - HTH_36 k59_297473_1 1120936.KB907208_gene1108 3.22e-48 166.0 COG0468@1|root,COG0468@2|Bacteria,2GJ4P@201174|Actinobacteria,4EGN4@85012|Streptosporangiales 201174|Actinobacteria L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage - - - - - - - - - - - - RecA k59_604376_1 1692249.A0A0K1RLN8_9CIRC 1.11e-16 81.3 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_546092_1 626418.bglu_1g20980 1.51e-13 74.7 COG3756@1|root,COG3756@2|Bacteria,1RFD3@1224|Proteobacteria,2VWCR@28216|Betaproteobacteria 28216|Betaproteobacteria S Protein of unknown function (DUF1376) - - - - - - - - - - - - DUF1376 k59_420415_1 1437824.BN940_06986 2.82e-57 197.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2VNHP@28216|Betaproteobacteria,3T3DM@506|Alcaligenaceae 28216|Betaproteobacteria S COG4626 Phage terminase-like protein, large subunit - - - - - - - - - - - - Terminase_1 k59_420423_1 626887.J057_01900 7.42e-08 55.8 2C2XN@1|root,32GT6@2|Bacteria,1REZE@1224|Proteobacteria,1SG9Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria S ERF superfamily - - - - - - - - - - - - ERF k59_420423_2 1265502.KB905977_gene528 6.07e-26 103.0 COG2197@1|root,COG2197@2|Bacteria,1NA3X@1224|Proteobacteria,2VWX0@28216|Betaproteobacteria,4AIQ3@80864|Comamonadaceae 28216|Betaproteobacteria KT HNH endonuclease - - - - - - - - - - - - HNH_3 k59_256730_1 1986029.Q9MBM3_9VIRU 1.82e-68 222.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_30194_3 290397.Adeh_3627 2.02e-25 100.0 COG1403@1|root,COG1403@2|Bacteria,1NI5K@1224|Proteobacteria 1224|Proteobacteria V HNH nucleases - - - - - - - - - - - - - k59_30194_4 1122201.AUAZ01000017_gene2960 9.1e-82 260.0 COG5362@1|root,COG5362@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Terminase_6C k59_462034_2 1230338.MOMA_06926 1.6e-48 176.0 COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,1RY1X@1236|Gammaproteobacteria 1236|Gammaproteobacteria S associated with various cellular activities - - - - - - - - - - - - AAA,AAA_5 k59_175195_1 637389.Acaty_c2719 8.72e-28 113.0 COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,1S8R3@1236|Gammaproteobacteria,2NCRE@225057|Acidithiobacillales 225057|Acidithiobacillales M Domain of unknown function (DUF4124) - - - - - - - - - - - - DUF4124,SLT k59_133874_1 388739.RSK20926_11829 9.91e-10 66.6 COG4733@1|root,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria,2TV2W@28211|Alphaproteobacteria 28211|Alphaproteobacteria S COG4733 Phage-related protein, tail component - - - - - - - - - - - - Phage-tail_3 k59_340955_1 411473.RUMCAL_00893 2.65e-14 77.8 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,3WH0A@541000|Ruminococcaceae 186801|Clostridia L helicase - - - - - - - - - - - - Helicase_C,SNF2_N k59_30202_1 1618256.A0A0C5IM93_9CIRC 2.86e-42 154.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_109821_2 411460.RUMTOR_02036 3.4e-29 118.0 2EWZQ@1|root,33QB0@2|Bacteria,1V0T1@1239|Firmicutes,249Z2@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_297533_1 1220714.L7TNL6_9CAUD 1.04e-40 155.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QJW9@10662|Myoviridae 10662|Myoviridae S nucleic acid binding - - - - - - - - - - - - - k59_399422_2 748449.Halha_0969 1.41e-39 146.0 COG0464@1|root,COG0464@2|Bacteria,1TPQZ@1239|Firmicutes,24BQK@186801|Clostridia,3WB5K@53433|Halanaerobiales 186801|Clostridia O PFAM ATPase family associated with various cellular activities (AAA) spoVK - - ko:K06413 - - - - ko00000 - - - AAA k59_280001_1 1123252.ATZF01000007_gene124 1.62e-53 185.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,27B1K@186824|Thermoactinomycetaceae 91061|Bacilli E DegT/DnrJ/EryC1/StrS aminotransferase family aspB GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297 2.6.1.1,2.6.1.14 ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R01346,R02433,R02619,R05052 RC00006,RC00025 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k59_360370_1 1530186.JQEY01000002_gene1537 1.88e-111 347.0 COG1061@1|root,COG1061@2|Bacteria,1MV9F@1224|Proteobacteria,2TUXC@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Type III restriction enzyme res subunit - - - ko:K19789 - - - - ko00000,ko03400 - - - DUF3427,HIT,Helicase_C,PLDc_2,ResIII,UPF0547 k59_52351_1 548476.cauri_2358 2.52e-08 59.7 COG0500@1|root,COG0500@2|Bacteria,2I2MK@201174|Actinobacteria,22KBE@1653|Corynebacteriaceae 201174|Actinobacteria Q (SAM)-dependent - GO:0008150,GO:0040007 - - - - - - - - - - Methyltransf_11 k59_630103_1 251221.35214278 9.11e-31 126.0 COG3291@1|root,COG3291@2|Bacteria 2|Bacteria S metallopeptidase activity - - - - - - - - - - - - Big_3_3,PA,Peptidase_M36,Peptidase_M43,REJ k59_280013_1 428127.EUBDOL_02260 3.43e-90 291.0 COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,3VNRB@526524|Erysipelotrichia 526524|Erysipelotrichia L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran k59_491046_1 1316927.ATKI01000032_gene4867 9.48e-05 50.4 COG0689@1|root,COG2931@1|root,COG0689@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria,1YSF7@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria Q Pectate lyase superfamily protein psmE - - - - - - - - - - - Beta_helix,Cadherin_3,DUF4114,He_PIG,HemolysinCabind,Pectate_lyase_3,Peptidase_M10,Peptidase_M10_C k59_346593_4 1168289.AJKI01000003_gene2831 7.71e-05 53.9 COG1196@1|root,COG1196@2|Bacteria,4PP9M@976|Bacteroidetes 976|Bacteroidetes D nuclear chromosome segregation - - - - - - - - - - - - - k59_655797_1 1475143.W8SNN0_9CIRC 2.42e-23 101.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_403622_2 1515615.HQ41_00660 7.11e-41 141.0 COG0780@1|root,COG0780@2|Bacteria,4NMSC@976|Bacteroidetes,2FRSH@200643|Bacteroidia,231X0@171551|Porphyromonadaceae 976|Bacteroidetes F Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) queF - 1.7.1.13 ko:K09457 ko00790,ko01100,map00790,map01100 - R07605 RC01875 ko00000,ko00001,ko01000,ko03016 - - - QueF k59_383925_1 1234888.K0A2J2_9VIRU 1.79e-57 194.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_75815_1 1453505.JASY01000013_gene4303 6.45e-08 59.3 COG3291@1|root,COG5184@1|root,COG3291@2|Bacteria,COG5184@2|Bacteria,4PI2H@976|Bacteroidetes,1IA3E@117743|Flavobacteriia,2NXN5@237|Flavobacterium 976|Bacteroidetes DZ Concanavalin A-like lectin/glucanases superfamily - - - - - - - - - - - - Laminin_G_3 k59_491537_3 936455.KI421499_gene5909 3.65e-27 117.0 COG3409@1|root,COG3772@1|root,COG3409@2|Bacteria,COG3772@2|Bacteria,1QW72@1224|Proteobacteria,2UBY3@28211|Alphaproteobacteria,3K0F5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Peptidoglycan-binding domain 1 protein - - - - - - - - - - - - - k59_552608_1 1340810.V5UTB4_9CAUD 1.45e-08 62.0 4QB3T@10239|Viruses,4QWCJ@35237|dsDNA viruses no RNA stage,4QS7B@28883|Caudovirales,4QK0J@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_113531_1 85929.N1QEF2 4.73e-08 62.4 COG3119@1|root,KOG3731@2759|Eukaryota,38E91@33154|Opisthokonta,3NVCA@4751|Fungi,3QR41@4890|Ascomycota,203NX@147541|Dothideomycetes,3MHTH@451867|Dothideomycetidae 4751|Fungi G Sulfatase - - - - - - - - - - - - Sulfatase k59_408759_3 1404245.CGLY_15325 0.000373 51.2 COG0584@1|root,COG0584@2|Bacteria,2GMMS@201174|Actinobacteria,22M3I@1653|Corynebacteriaceae 201174|Actinobacteria C glycerophosphoryl diester phosphodiesterase glpQ - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD k59_285060_1 1173762.S4TU76_9CAUD 2.02e-73 243.0 4QF3C@10239|Viruses,4QWIA@35237|dsDNA viruses no RNA stage,4QU4U@28883|Caudovirales,4QNNQ@10744|Podoviridae 10744|Podoviridae S host cell wall - - - - - - - - - - - - - k59_221280_2 500632.CLONEX_02252 1.29e-62 206.0 COG0270@1|root,COG0270@2|Bacteria,1TS3G@1239|Firmicutes,249Q9@186801|Clostridia 186801|Clostridia H Psort location Cytoplasmic, score - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_161828_1 382245.ASA_1776 2.18e-15 78.6 COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,1RNQZ@1236|Gammaproteobacteria,1Y4UA@135624|Aeromonadales 135624|Aeromonadales H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds queE - 4.3.99.3 ko:K10026 ko00790,ko01100,map00790,map01100 - R10002 RC02989 ko00000,ko00001,ko01000,ko03016 - - - Fer4_14,Radical_SAM k59_430241_1 1475143.W8SNN0_9CIRC 4.43e-23 99.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_430241_3 1379692.S5SXY7_9CIRC 2.68e-23 102.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_572701_1 27923.ML131119a-PA 3.61e-05 55.8 COG0417@1|root,KOG2242@1|root,KOG0970@2759|Eukaryota,KOG2242@2759|Eukaryota,38CZ4@33154|Opisthokonta,3BBX1@33208|Metazoa 33208|Metazoa L DNA polymerase POLA1 GO:0000082,GO:0000083,GO:0000166,GO:0000228,GO:0000278,GO:0000428,GO:0000723,GO:0000726,GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003690,GO:0003824,GO:0003887,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005654,GO:0005657,GO:0005658,GO:0005694,GO:0005730,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006270,GO:0006271,GO:0006272,GO:0006273,GO:0006281,GO:0006302,GO:0006303,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007049,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0012505,GO:0016043,GO:0016070,GO:0016363,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018130,GO:0019103,GO:0019219,GO:0019222,GO:0019438,GO:0019725,GO:0019899,GO:0019900,GO:0019901,GO:0022402,GO:0022616,GO:0030880,GO:0030894,GO:0031323,GO:0031326,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032200,GO:0032201,GO:0032774,GO:0032991,GO:0032993,GO:0033260,GO:0033554,GO:0034061,GO:0034399,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0042592,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043596,GO:0043601,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044454,GO:0044464,GO:0044770,GO:0044772,GO:0044786,GO:0044843,GO:0046483,GO:0046982,GO:0046983,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051276,GO:0051716,GO:0055029,GO:0060249,GO:0060255,GO:0061695,GO:0065007,GO:0065008,GO:0070013,GO:0071704,GO:0071840,GO:0071897,GO:0080090,GO:0090304,GO:0097159,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1903047,GO:1903506,GO:1990234,GO:2000112,GO:2001141 2.7.7.7 ko:K02320 ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030 M00261 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032 - - - DNA_pol_B,DNA_pol_B_exo1,DNA_pol_alpha_N,zf-DNA_Pol k59_593593_1 1692257.A0A0K1RL39_9CIRC 7.93e-35 135.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_306450_1 639283.Snov_0004 5.49e-18 94.7 COG0863@1|root,COG0863@2|Bacteria,1PCSC@1224|Proteobacteria,2U4M6@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_326856_2 1234888.K0A2J2_9VIRU 6.88e-142 424.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_39982_1 1449126.JQKL01000003_gene1702 2.87e-11 61.2 COG4570@1|root,COG4570@2|Bacteria,1VFJ9@1239|Firmicutes,24NSB@186801|Clostridia 186801|Clostridia L Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC - - - - - - - - - - - - RusA k59_511074_1 484022.Fphi_1038 1.41e-09 65.5 COG0507@1|root,COG0507@2|Bacteria,1QFB2@1224|Proteobacteria,1SE0Z@1236|Gammaproteobacteria,46326@72273|Thiotrichales 72273|Thiotrichales L PIF1-like helicase - - - - - - - - - - - - AAA_30,UvrD_C_2,Viral_helicase1 k59_365251_1 994573.T472_0208830 1.42e-28 124.0 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,2487V@186801|Clostridia,36EDD@31979|Clostridiaceae 186801|Clostridia L DNA polymerase - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_326895_1 1449351.RISW2_21770 8.51e-11 73.6 COG1196@1|root,COG3941@1|root,COG1196@2|Bacteria,COG3941@2|Bacteria 2|Bacteria O tape measure - - - - - - - - - - - - PhageMin_Tail,TMP_2,Tape_meas_lam_C k59_430298_1 272558.10175535 2.05e-07 57.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4HAIF@91061|Bacilli,1ZBZT@1386|Bacillus 91061|Bacilli L COG0553 Superfamily II DNA RNA helicases, SNF2 family ywqA - - - - - - - - - - - DUF3670,Helicase_C,SNF2_N k59_80904_1 1980924.B2ZYD3_9CAUD 2.65e-52 179.0 4QBA2@10239|Viruses,4QPPI@28883|Caudovirales,4QIA3@10662|Myoviridae 10662|Myoviridae S Thymidylate synthase - - - - - - - - - - - - - k59_593623_1 1370121.AUWS01000040_gene4243 5.97e-09 67.0 COG0305@1|root,COG1372@1|root,COG0305@2|Bacteria,COG1372@2|Bacteria,2GKXQ@201174|Actinobacteria,234JE@1762|Mycobacteriaceae 201174|Actinobacteria L Participates in initiation and elongation during chromosome replication dnaB GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0030312,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3 k59_221375_3 953739.SVEN_2157 2.68e-35 135.0 2DWRB@1|root,341IF@2|Bacteria,2ID68@201174|Actinobacteria 201174|Actinobacteria S Domain of unknown function (DUF5047) - - - - - - - - - - - - DUF5047 k59_285163_1 530564.Psta_2054 5.83e-05 48.1 COG1361@1|root,COG1361@2|Bacteria,2IYS8@203682|Planctomycetes 203682|Planctomycetes M Domain of unknown function DUF11 - - - - - - - - - - - - DUF11 k59_246288_2 1234888.K0A2J2_9VIRU 2.19e-163 478.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_553875_1 1692259.A0A0K1RL59_9CIRC 1.02e-21 97.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_41187_2 1123518.ARWI01000001_gene1155 5.38e-27 106.0 COG1525@1|root,COG1525@2|Bacteria,1N0I9@1224|Proteobacteria,1S8DU@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Staphylococcal nuclease homologue - - - - - - - - - - - - SNase k59_20739_3 105154.Q9MBU6_9VIRU 9.18e-93 300.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_20739_4 1165094.RINTHH_3920 5.14e-06 55.1 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_594852_1 1197951.I6S6K3_9CAUD 3.94e-06 58.2 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales 28883|Caudovirales S N-acetylmuramoyl-L-alanine amidase activity - - - - - - - - - - - - - k59_369237_22 1121285.AUFK01000002_gene13 1.63e-56 187.0 COG1235@1|root,COG1235@2|Bacteria,4NDVI@976|Bacteroidetes,1I7IQ@117743|Flavobacteriia 976|Bacteroidetes S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B,Lactamase_B_2 k59_20748_1 1054213.HMPREF9946_02152 1.4e-14 83.2 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2TTEX@28211|Alphaproteobacteria,2JVUB@204441|Rhodospirillales 204441|Rhodospirillales S Terminase - - - - - - - - - - - - Terminase_1 k59_533488_1 313606.M23134_07327 2.76e-48 172.0 COG1783@1|root,COG1783@2|Bacteria,4NSZ4@976|Bacteroidetes,47P61@768503|Cytophagia 976|Bacteroidetes S phage Terminase large subunit - - - - - - - - - - - - - k59_225812_2 553218.CAMRE0001_2407 8.45e-22 94.0 COG0863@1|root,COG0863@2|Bacteria,1NQ2A@1224|Proteobacteria 1224|Proteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - - - - - - - - - - - N6_N4_Mtase k59_328343_1 332101.JIBU02000018_gene2291 3.55e-09 62.8 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,248A4@186801|Clostridia,36E3C@31979|Clostridiaceae 186801|Clostridia M penicillin-binding protein 1A - - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase k59_61701_3 1219065.VPR01S_01_02560 6.11e-08 59.7 2C3WM@1|root,3002C@2|Bacteria,1RDC0@1224|Proteobacteria,1TIHI@1236|Gammaproteobacteria,1XZ4X@135623|Vibrionales 135623|Vibrionales S Domain of unknown function (DUF4326) - - - - - - - - - - - - DUF4326 k59_41219_1 691965.D4P7I3_9CAUD 4.87e-83 278.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_413695_1 1429767.W6B150_9CAUD 2.75e-95 305.0 4QF3C@10239|Viruses,4QWIA@35237|dsDNA viruses no RNA stage,4QU4U@28883|Caudovirales,4QNNQ@10744|Podoviridae 10744|Podoviridae S host cell wall - - - - - - - - - - - - - k59_86284_2 1379722.S5SY31_9CIRC 3.52e-72 229.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_188235_1 575540.Isop_1325 6.2e-06 53.5 COG0587@1|root,COG0587@2|Bacteria,2IYGA@203682|Planctomycetes 203682|Planctomycetes L DNA polymerase III alpha subunit - - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k59_43997_1 747365.Thena_0773 2.68e-38 139.0 COG1573@1|root,COG1573@2|Bacteria,1V267@1239|Firmicutes,24DFW@186801|Clostridia,42G30@68295|Thermoanaerobacterales 186801|Clostridia L TIGRFAM Phage SPO1 DNA polymerase-related protein - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k59_250161_1 1175654.A0A0S0MVN0_9CAUD 2.41e-62 201.0 4QFED@10239|Viruses,4R072@35237|dsDNA viruses no RNA stage,4QPEH@28883|Caudovirales,4QN2V@10699|Siphoviridae 10699|Siphoviridae S tRNA modification - - - - - - - - - - - - - k59_577798_2 1524880.A0A076G7R3_9VIRU 2.02e-50 171.0 4QAUS@10239|Viruses 10239|Viruses S flavin adenine dinucleotide binding - - - - - - - - - - - - - k59_228792_1 1234888.K0A2J2_9VIRU 5.71e-13 73.6 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_105310_1 1124780.ANNU01000013_gene3877 4.79e-47 173.0 COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,47NQV@768503|Cytophagia 976|Bacteroidetes F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrd - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_lgC,Ribonuc_red_lgN k59_270100_1 1528098.NOVO_00290 1.78e-14 74.3 COG2131@1|root,COG2131@2|Bacteria,1RD1P@1224|Proteobacteria,2UD7X@28211|Alphaproteobacteria,47G99@766|Rickettsiales 766|Rickettsiales F MafB19-like deaminase - - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 k59_640367_1 1121360.AUAQ01000003_gene2057 2.36e-33 139.0 COG5412@1|root,COG5412@2|Bacteria,2IH91@201174|Actinobacteria 201174|Actinobacteria E phage tail tape measure protein - - - - - - - - - - - - - k59_538110_1 2002.JOEQ01000023_gene1166 2.58e-05 49.7 COG1396@1|root,COG1396@2|Bacteria,2GP3T@201174|Actinobacteria 201174|Actinobacteria K Helix-turn-helix domain protein - - - - - - - - - - - - HTH_3,HTH_31 k59_517436_1 172088.AUGA01000033_gene4641 3.17e-58 189.0 2CXZV@1|root,32T32@2|Bacteria,1N4R9@1224|Proteobacteria,2UM96@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_126981_3 742725.HMPREF9450_00223 0.000239 52.4 COG5434@1|root,COG5434@2|Bacteria,4NFSC@976|Bacteroidetes,2FNQN@200643|Bacteroidia 976|Bacteroidetes G Belongs to the glycosyl hydrolase 28 family - - - - - - - - - - - - Glyco_hydro_28,Pectate_lyase_3 k59_372842_2 1692255.A0A0K1RL52_9CIRC 3.09e-75 239.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_310854_1 10224.XP_006811177.1 1.1e-57 211.0 COG0553@1|root,KOG1000@2759|Eukaryota,38C05@33154|Opisthokonta,3BE0M@33208|Metazoa,3CT9F@33213|Bilateria 33208|Metazoa B SWI SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein ZRANB3 GO:0000018,GO:0000228,GO:0000733,GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005657,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006275,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0008156,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010556,GO:0010558,GO:0010605,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0017111,GO:0019219,GO:0019222,GO:0031297,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031593,GO:0031974,GO:0031981,GO:0032392,GO:0033554,GO:0034641,GO:0034645,GO:0036292,GO:0036310,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043596,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0045005,GO:0045910,GO:0045934,GO:0046483,GO:0048478,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0065007,GO:0070013,GO:0070530,GO:0071103,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090329,GO:0097159,GO:0097617,GO:0140030,GO:0140097,GO:1901360,GO:1901363,GO:1901576,GO:2000104,GO:2000112,GO:2000113 - - - - - - - - - - HNH,Helicase_C,SNF2_N,zf-RanBP k59_414016_2 999541.bgla_1g14450 1.64e-77 246.0 28HEE@1|root,2Z7QU@2|Bacteria,1MXU6@1224|Proteobacteria,2VISI@28216|Betaproteobacteria,1K35U@119060|Burkholderiaceae 28216|Betaproteobacteria S Domain of unknown function (DUF932) - - - - - - - - - - - - DUF932 k59_476743_1 1408823.AXUS01000024_gene2728 7.88e-17 89.7 COG5281@1|root,COG5281@2|Bacteria,1TPWF@1239|Firmicutes,24A8R@186801|Clostridia,25SJX@186804|Peptostreptococcaceae 186801|Clostridia S tape measure - - - - - - - - - - - - PhageMin_Tail k59_557470_2 1204539.J9QPV1_9CAUD 1.45e-21 87.8 4QB07@10239|Viruses,4QUZW@35237|dsDNA viruses no RNA stage,4QPGS@28883|Caudovirales,4QMBY@10699|Siphoviridae 10699|Siphoviridae S Domain of unknown function (DUF4326) - - - - - - - - - - - - - k59_90773_1 714943.Mucpa_3836 1.92e-07 63.2 COG3391@1|root,COG4677@1|root,COG3391@2|Bacteria,COG4677@2|Bacteria 2|Bacteria G pectinesterase activity - - - - - - - - - - - - Cadherin,NHL,RicinB_lectin_2 k59_542517_3 536233.CLO_0532 1.01e-11 70.9 COG1783@1|root,COG1783@2|Bacteria,1TRQP@1239|Firmicutes,248E9@186801|Clostridia,36EE3@31979|Clostridiaceae 186801|Clostridia L Phage terminase, large subunit, PBSX family - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C k59_439763_1 1385658.U5KPZ6_9VIRU 1.77e-50 177.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_337333_2 1788442.A0A190WH98_9CIRC 3.31e-20 95.9 4QB6C@10239|Viruses,4QUKM@29258|ssDNA viruses 10239|Viruses J Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_522044_2 326298.Suden_1782 3.51e-45 164.0 COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,42QA8@68525|delta/epsilon subdivisions,2YNH6@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria S PFAM ATPase family associated with various cellular activities (AAA) - - - - - - - - - - - - AAA_3 k59_130879_2 1048207.F8UBT5_9CAUD 6.36e-34 122.0 4QH92@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_273771_1 66869.JNXG01000002_gene6367 5.27e-38 145.0 COG4974@1|root,COG4974@2|Bacteria,2HD2H@201174|Actinobacteria,41BHU@629295|Streptomyces griseus group 201174|Actinobacteria L Phage integrase family - - - - - - - - - - - - Phage_int_SAM_3,Phage_integrase k59_623217_1 399739.Pmen_3992 4.82e-41 149.0 28MC2@1|root,2ZAQD@2|Bacteria,1R5I0@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - ParBc k59_337372_1 1235803.C825_03383 3.34e-17 77.0 2ETIK@1|root,33M2E@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_90852_3 33876.JNXY01000004_gene1766 2.61e-08 51.6 2CHCE@1|root,325FJ@2|Bacteria,2HAM1@201174|Actinobacteria 201174|Actinobacteria S Transmembrane Fragile-X-F protein - - - - - - - - - - - - Tmemb_185A k59_8166_1 1692242.A0A0K1RKZ2_9CIRC 1.76e-43 157.0 4QFEW@10239|Viruses,4QUKZ@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_8166_2 1692250.A0A0K1RLR1_9CIRC 1.18e-84 263.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_376668_1 313606.M23134_05534 0.000182 48.1 COG0705@1|root,COG0705@2|Bacteria,4NGT3@976|Bacteroidetes,47R3F@768503|Cytophagia 976|Bacteroidetes S Rhomboid family - - - - - - - - - - - - Rhomboid k59_130927_1 1906.SFRA_26500 1.39e-16 83.2 COG0739@1|root,COG1652@1|root,COG0739@2|Bacteria,COG1652@2|Bacteria,2GK68@201174|Actinobacteria 201174|Actinobacteria M domain protein - - - ko:K21687 - - - - ko00000 - GH23 - LysM,Peptidase_M23,Transglycosylas k59_130927_2 1486472.A0A068F3I8_9CAUD 1.38e-40 150.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QM52@10699|Siphoviridae 10699|Siphoviridae S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor - - - - - - - - - - - - - k59_646523_1 1321782.HMPREF1986_02255 3.63e-32 127.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,2PRYV@265975|Oribacterium 186801|Clostridia L SNF2 family N-terminal domain - - - - - - - - - - - - SNF2_N k59_131779_1 186617.M9M8L2_9VIRU 2.1e-37 143.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_8948_2 31535.Q9MC91_BPD3 5.06e-22 96.3 4QBHW@10239|Viruses,4QW8N@35237|dsDNA viruses no RNA stage,4QTT7@28883|Caudovirales,4QN92@10699|Siphoviridae 10699|Siphoviridae S sequence-specific DNA binding transcription factor activity - - - - - - - - - - - - - k59_232928_1 1540097.A0A0A0YU43_9CAUD 6.52e-42 152.0 4QBMV@10239|Viruses,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_254825_1 1321779.HMPREF1984_00484 3.99e-21 92.4 COG0052@1|root,COG0052@2|Bacteria,3795U@32066|Fusobacteria 32066|Fusobacteria J Belongs to the universal ribosomal protein uS2 family rpsB GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02967 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S2 k59_254825_2 869210.Marky_1198 2.91e-46 156.0 COG0264@1|root,COG0264@2|Bacteria,1WJ3W@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS k59_151444_1 1120936.KB907208_gene1108 2.85e-32 122.0 COG0468@1|root,COG0468@2|Bacteria,2GJ4P@201174|Actinobacteria,4EGN4@85012|Streptosporangiales 201174|Actinobacteria L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage - - - - - - - - - - - - RecA k59_47949_3 525255.HMPREF0077_0992 5.54e-17 82.0 COG5492@1|root,COG5492@2|Bacteria,1V2Y7@1239|Firmicutes,25NMA@186801|Clostridia,22IIR@1570339|Peptoniphilaceae 186801|Clostridia N domain, Protein - - - - - - - - - - - - - k59_47949_4 1214184.ALKY01000039_gene912 2.81e-10 63.2 COG5492@1|root,COG5492@2|Bacteria,1V2Y7@1239|Firmicutes,4HGHB@91061|Bacilli,1WU07@1307|Streptococcus suis 91061|Bacilli N domain, Protein - - - - - - - - - - - - - k59_314555_1 1122201.AUAZ01000007_gene3692 1.56e-08 57.4 28H5T@1|root,2Z7IB@2|Bacteria,1N7V9@1224|Proteobacteria,1S23F@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_314555_2 35754.JNYJ01000015_gene8535 8.38e-109 325.0 COG0451@1|root,COG0451@2|Bacteria,2IDID@201174|Actinobacteria 201174|Actinobacteria GM GDP-mannose 4,6 dehydratase - - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase k59_108612_1 266762.HQ36_05355 3.04e-41 140.0 COG3023@1|root,COG3023@2|Bacteria,4NQ2J@976|Bacteroidetes,2FS4K@200643|Bacteroidia,230M3@171551|Porphyromonadaceae 976|Bacteroidetes V Ami_2 - - 3.5.1.28 ko:K01447 - - R04112 RC00064,RC00141 ko00000,ko01000 - - - Amidase_2 k59_482838_1 1692250.A0A0K1RLR1_9CIRC 8.61e-51 178.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_192834_1 1028806.GGE_2172 2.26e-26 117.0 COG1196@1|root,COG5281@1|root,COG1196@2|Bacteria,COG5281@2|Bacteria,1MX2R@1224|Proteobacteria,1SYI1@1236|Gammaproteobacteria 1236|Gammaproteobacteria D tape measure protein - - - - - - - - - - - - Phage_HK97_TLTM k59_355431_1 557598.LHK_01799 1.16e-16 81.6 COG0582@1|root,COG0582@2|Bacteria,1NWGS@1224|Proteobacteria,2VKWM@28216|Betaproteobacteria,2KR09@206351|Neisseriales 206351|Neisseriales L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_integrase k59_418413_2 145579.CAPSD_BPPHM 4.52e-81 268.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_296129_2 1788452.A0A190WHG0_9CIRC 2.4e-56 190.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_624701_1 28229.ND2E_3441 1.83e-37 137.0 COG1196@1|root,COG1196@2|Bacteria,1NK8W@1224|Proteobacteria,1SGJD@1236|Gammaproteobacteria 1236|Gammaproteobacteria D DNA N-6-adenine-methyltransferase (Dam) - - - - - - - - - - - - Dam k59_132466_1 406818.XBJ1_2997 2.26e-07 58.2 COG4675@1|root,COG5301@1|root,COG4675@2|Bacteria,COG5301@2|Bacteria,1RDJW@1224|Proteobacteria,1S415@1236|Gammaproteobacteria 1236|Gammaproteobacteria S tail collar domain protein - - - - - - - - - - - - Collar,Phage_fiber_2 k59_500786_1 435591.BDI_0861 7.13e-55 183.0 COG0270@1|root,COG0270@2|Bacteria,4NJPP@976|Bacteroidetes,2FKYT@200643|Bacteroidia 976|Bacteroidetes H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_500786_3 1121370.AQUY01000004_gene1330 1.74e-37 141.0 COG0305@1|root,COG0305@2|Bacteria,2GKXQ@201174|Actinobacteria,22K4C@1653|Corynebacteriaceae 201174|Actinobacteria L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_136636_8 1094980.Mpsy_2316 4.72e-12 75.9 COG0582@1|root,arCOG01242@2157|Archaea,2Y83U@28890|Euryarchaeota,2NAAN@224756|Methanomicrobia 224756|Methanomicrobia L Phage integrase family - - - - - - - - - - - - Phage_int_SAM_4,Phage_integrase k59_654533_1 1297863.APJF01000020_gene2704 2.86e-13 76.6 28JTG@1|root,2Z9IR@2|Bacteria,1R0GC@1224|Proteobacteria,2TURR@28211|Alphaproteobacteria,3JUCC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF2793) - - - - - - - - - - - - DUF2793 k59_447482_1 626418.bglu_1g20980 1.06e-11 70.9 COG3756@1|root,COG3756@2|Bacteria,1RFD3@1224|Proteobacteria,2VWCR@28216|Betaproteobacteria 28216|Betaproteobacteria S Protein of unknown function (DUF1376) - - - - - - - - - - - - DUF1376 k59_629213_1 1229276.DI53_1624 2.92e-22 98.2 COG0270@1|root,COG0270@2|Bacteria,4NJPP@976|Bacteroidetes,1IYYG@117747|Sphingobacteriia 976|Bacteroidetes L C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_489948_1 1499684.CCNP01000020_gene2299 0.000519 47.8 COG4974@1|root,COG4974@2|Bacteria,1UTX8@1239|Firmicutes,24DFG@186801|Clostridia,36E3B@31979|Clostridiaceae 186801|Clostridia L Belongs to the 'phage' integrase family - - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_int_SAM_4,Phage_int_SAM_5,Phage_integrase k59_607916_1 27923.ML104626a-PA 1.96e-25 101.0 2AUXR@1|root,2RZV2@2759|Eukaryota,39BV2@33154|Opisthokonta,3BKHA@33208|Metazoa 33208|Metazoa - - - - - - - - - - - - - - - k59_654574_2 292459.STH2807 2.67e-15 73.6 COG0662@1|root,COG0662@2|Bacteria,1V3H4@1239|Firmicutes,24HNT@186801|Clostridia 186801|Clostridia G Cupin 2, conserved barrel domain protein - - - - - - - - - - - - Cupin_2 k59_505117_1 1116482.K9L5J1_9CAUD 3.73e-15 73.9 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales 28883|Caudovirales S HNH endonuclease - - - - - - - - - - - - - k59_51679_1 1291743.LOSG293_110580 3.47e-35 130.0 2DPIQ@1|root,3328X@2|Bacteria,1VFYC@1239|Firmicutes,4HNHQ@91061|Bacilli,3F5FA@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - AP2 k59_447525_1 926549.KI421517_gene2345 3.68e-57 191.0 COG1783@1|root,COG1783@2|Bacteria,4PMA2@976|Bacteroidetes,47RRH@768503|Cytophagia 976|Bacteroidetes S Terminase RNAseH like domain - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C k59_279281_1 1274524.BSONL12_23100 2.94e-08 60.1 COG0417@1|root,COG0417@2|Bacteria,1TQJQ@1239|Firmicutes,4HF6F@91061|Bacilli,1ZF50@1386|Bacillus 91061|Bacilli L DNA polymerase elongation subunit (Family B) - - - - - - - - - - - - - k59_14252_2 1327970.R9ZVU4_9CAUD 5.67e-10 64.3 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales,4QKM7@10699|Siphoviridae 10699|Siphoviridae S HNH endonuclease - - - - - - - - - - - - - k59_402601_1 186617.M9M8L2_9VIRU 3.24e-58 196.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_359842_1 1572715.A0A0A7TXC8_9CAUD 2.03e-47 164.0 4QBA2@10239|Viruses,4QPPI@28883|Caudovirales,4QM0B@10699|Siphoviridae 10699|Siphoviridae S Thymidylate synthase - GO:0003674,GO:0003824,GO:0004799,GO:0008150,GO:0008152,GO:0008168,GO:0016740,GO:0016741,GO:0032259,GO:0042083 - - - - - - - - - - - k59_359842_3 1538804.A0A088F6T3_9CAUD 5.62e-65 223.0 4QAKM@10239|Viruses,4QPEF@28883|Caudovirales,4QKNE@10699|Siphoviridae 10699|Siphoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_359845_1 1380387.JADM01000008_gene930 1.41e-34 137.0 COG5283@1|root,COG5283@2|Bacteria,1NFKU@1224|Proteobacteria,1RP2D@1236|Gammaproteobacteria,1XKUI@135619|Oceanospirillales 135619|Oceanospirillales S Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_447563_1 1122225.AULQ01000009_gene341 2.43e-30 129.0 2EAST@1|root,334US@2|Bacteria,4NRGD@976|Bacteroidetes,1I583@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_81056_2 1096546.WYO_0171 1.53e-58 201.0 COG0553@1|root,COG0553@2|Bacteria,1PXS8@1224|Proteobacteria,2UAZ5@28211|Alphaproteobacteria 28211|Alphaproteobacteria KL COG0553 Superfamily II DNA RNA helicases, SNF2 family - - - - - - - - - - - - SNF2_N k59_81071_1 1210908.HSB1_44590 1.05e-05 52.0 COG0500@1|root,arCOG01402@2157|Archaea,2XYWP@28890|Euryarchaeota,23WPJ@183963|Halobacteria 183963|Halobacteria Q COG0500 SAM-dependent methyltransferases - - - - - - - - - - - - Methyltransf_21 k59_118950_2 1247024.JRLH01000003_gene327 0.000215 46.6 2DY6H@1|root,348CU@2|Bacteria,1NQ66@1224|Proteobacteria,1SRHE@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_244190_1 1457393.AZ09_06195 1.91e-18 80.9 COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,2TSAM@28211|Alphaproteobacteria,2JPX2@204441|Rhodospirillales 204441|Rhodospirillales O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA - 1.8.4.11 ko:K07304 - - - - ko00000,ko01000 - - - PMSR k59_244190_2 1121405.dsmv_1161 4.24e-138 412.0 COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,42M04@68525|delta/epsilon subdivisions,2WJJD@28221|Deltaproteobacteria,2MIN7@213118|Desulfobacterales 28221|Deltaproteobacteria J Belongs to the class-I aminoacyl-tRNA synthetase family cysS GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e,tRNA-synt_1g k59_244193_1 105154.Q9MBU6_9VIRU 1.51e-197 570.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_223579_4 391612.CY0110_08961 1.09e-74 243.0 COG3179@1|root,COG4990@1|root,COG3179@2|Bacteria,COG4990@2|Bacteria,1GR5P@1117|Cyanobacteria,3KIMF@43988|Cyanothece 1117|Cyanobacteria S Peptidase_C39 like family - - - - - - - - - - - - Peptidase_C39_2 k59_309560_1 1343740.M271_23110 7.75e-05 46.2 COG0568@1|root,COG0568@2|Bacteria,2I7WF@201174|Actinobacteria 201174|Actinobacteria K Sigma-70, region 4 - - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r3,Sigma70_r4 k59_371586_5 338969.Rfer_1436 3.8e-11 71.2 COG1793@1|root,COG1793@2|Bacteria,1MUW3@1224|Proteobacteria,2VI3P@28216|Betaproteobacteria,4ABUA@80864|Comamonadaceae 28216|Betaproteobacteria L DNA ligase dnaL - 6.5.1.1,6.5.1.6,6.5.1.7 ko:K10747 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00381,R00382,R10822,R10823 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - DNA_ligase_A_M,DNA_ligase_OB_2 k59_371586_6 765913.ThidrDRAFT_3685 5.71e-162 461.0 COG0451@1|root,COG0451@2|Bacteria,1MUGT@1224|Proteobacteria,1RMPQ@1236|Gammaproteobacteria,1WVWB@135613|Chromatiales 135613|Chromatiales GM Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction fcl - 1.1.1.271 ko:K02377 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R05692 RC01014 ko00000,ko00001,ko01000 - - - Epimerase k59_371586_7 765913.ThidrDRAFT_3683 7.4e-176 498.0 COG1089@1|root,COG1089@2|Bacteria,1MUX0@1224|Proteobacteria,1RMIY@1236|Gammaproteobacteria,1WWR3@135613|Chromatiales 135613|Chromatiales M Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose gmd - 4.2.1.47 ko:K01711 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R00888 RC00402 ko00000,ko00001,ko01000 - - - GDP_Man_Dehyd k59_309567_2 1325372.N0DPG8_9CAUD 7.25e-20 89.0 4QBHW@10239|Viruses,4QW8N@35237|dsDNA viruses no RNA stage,4QTT7@28883|Caudovirales,4QJZQ@10662|Myoviridae 10662|Myoviridae S sequence-specific DNA binding transcription factor activity - - - - - - - - - - - - - k59_494823_1 326424.FRAAL6260 1.15e-08 64.7 COG1404@1|root,COG1404@2|Bacteria,2GIRE@201174|Actinobacteria,4EW2X@85013|Frankiales 201174|Actinobacteria O Subtilase family mycP - - ko:K14743 - - - - ko00000,ko01000,ko01002,ko03110 - - - Peptidase_S8 k59_206897_1 1234888.K0A2J2_9VIRU 4.16e-105 324.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_597086_2 765913.ThidrDRAFT_1101 6.24e-05 54.3 COG3598@1|root,COG3598@2|Bacteria,1PWN4@1224|Proteobacteria,1T47X@1236|Gammaproteobacteria 1236|Gammaproteobacteria L AAA domain - - - - - - - - - - - - AAA_25 k59_23006_1 1788447.A0A190WHJ9_9CIRC 8.08e-59 192.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_125577_2 871584.D9ZNE3_9CAUD 7.8e-67 217.0 4QE60@10239|Viruses,4QZTN@35237|dsDNA viruses no RNA stage,4QQMB@28883|Caudovirales,4QKS8@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_618376_2 1158165.KB898873_gene350 7.76e-32 113.0 2DSMC@1|root,33GP4@2|Bacteria,1NCDH@1224|Proteobacteria,1T10M@1236|Gammaproteobacteria,1X1TS@135613|Chromatiales 135613|Chromatiales S Domain of unknown function (DUF4326) - - - - - - - - - - - - DUF4326 k59_556214_1 351016.RAZWK3B_16615 4.77e-16 83.2 2FFRP@1|root,347NW@2|Bacteria,1P2BR@1224|Proteobacteria,2UVQC@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_494868_1 1484460.JSWG01000001_gene2443 1.02e-08 63.2 COG3420@1|root,COG5295@1|root,COG3420@2|Bacteria,COG5295@2|Bacteria,4NJTK@976|Bacteroidetes,1HZNB@117743|Flavobacteriia 976|Bacteroidetes UW surface antigen - - - - - - - - - - - - Peptidase_S74,YadA_head k59_351007_2 1173762.S4TT79_9CAUD 1.31e-56 186.0 4QGM6@10239|Viruses,4QYNV@35237|dsDNA viruses no RNA stage,4QRH4@28883|Caudovirales,4QP0P@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_559398_5 1128912.GMES_4151 4.12e-09 57.4 COG0745@1|root,COG0745@2|Bacteria,1RD9E@1224|Proteobacteria,1S3PS@1236|Gammaproteobacteria,46DAR@72275|Alteromonadaceae 1236|Gammaproteobacteria T Helix-turn-helix domain - - - - - - - - - - - - HTH_17,Response_reg k59_457794_1 1218084.BBJK01000077_gene5333 2.54e-127 382.0 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,2VP7E@28216|Betaproteobacteria,1KFK1@119060|Burkholderiaceae 28216|Betaproteobacteria S Phage portal protein - - - - - - - - - - - - Phage_portal k59_457812_1 391038.Bphy_1861 1.68e-36 134.0 2CWXD@1|root,32T0J@2|Bacteria,1N3Z7@1224|Proteobacteria,2VUEJ@28216|Betaproteobacteria,1K8Z8@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_540646_1 1206558.I7LHB5_9CAUD 1.24e-05 52.8 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QI82@10662|Myoviridae 10662|Myoviridae S virus tail, fiber - GO:0005575,GO:0019012 - - - - - - - - - - - k59_643714_2 1444310.JANV01000096_gene3232 4.18e-21 93.2 COG0270@1|root,COG0270@2|Bacteria,1V3W2@1239|Firmicutes 1239|Firmicutes L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K17398 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko03032,ko03036 - - - DNA_methylase k59_170758_1 195253.Syn6312_2899 1.14e-54 186.0 COG1403@1|root,COG1403@2|Bacteria,1G2XW@1117|Cyanobacteria 1117|Cyanobacteria L HNH endonuclease - - - - - - - - - - - - HNH,HNH_5,RRXRR k59_26547_1 5762.XP_002679146.1 1.92e-80 261.0 COG1372@1|root,2QRRC@2759|Eukaryota 2759|Eukaryota L reductase - GO:0003674,GO:0003824,GO:0004748,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009141,GO:0009142,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - Ribonuc_red_lgC k59_231190_3 1357279.N018_05420 5.97e-05 47.8 2E1G4@1|root,32WUP@2|Bacteria,1N4N0@1224|Proteobacteria,1SQHB@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_541171_1 1157708.KB907450_gene5414 7.04e-43 147.0 COG1403@1|root,COG1403@2|Bacteria 2|Bacteria V endonuclease activity - - - - - - - - - - - - HNH,HNH_5 k59_520876_2 1123276.KB893263_gene4649 1e-46 172.0 COG0582@1|root,COG0582@2|Bacteria,4NDZJ@976|Bacteroidetes,47P6T@768503|Cytophagia 976|Bacteroidetes L Phage integrase SAM-like domain - - - - - - - - - - - - Phage_int_SAM_5,Phage_integrase k59_458203_2 1195073.I6WLM5_9CAUD 2.36e-35 128.0 4QBHW@10239|Viruses,4QW8N@35237|dsDNA viruses no RNA stage,4QTT7@28883|Caudovirales,4QNKM@10744|Podoviridae 10744|Podoviridae S transferase activity, transferring alkyl or aryl (other than methyl) groups - - - - - - - - - - - - - k59_277283_1 1237149.C900_02841 0.000714 43.9 COG1396@1|root,COG1396@2|Bacteria 2|Bacteria K sequence-specific DNA binding - - - - - - - - - - - - HTH_3 k59_277283_5 391625.PPSIR1_21429 8.26e-27 115.0 COG0582@1|root,COG0582@2|Bacteria,1MWBN@1224|Proteobacteria,42QZQ@68525|delta/epsilon subdivisions,2WMV8@28221|Deltaproteobacteria,2YVB0@29|Myxococcales 28221|Deltaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase k59_503094_1 156889.Mmc1_1299 2.07e-17 83.6 2CWXD@1|root,32T0J@2|Bacteria,1N3Z7@1224|Proteobacteria,2UMWB@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_463229_1 932213.SPM24T3_04851 9.86e-18 82.8 COG0317@1|root,COG0317@2|Bacteria,1RGUA@1224|Proteobacteria,1S6AN@1236|Gammaproteobacteria,401C6@613|Serratia 1236|Gammaproteobacteria KT HD domain rela3 - - - - - - - - - - - HD_4 k59_72430_5 1173762.S4TRS0_9CAUD 3.66e-21 94.4 4QDXM@10239|Viruses,4QWIX@35237|dsDNA viruses no RNA stage,4QQF6@28883|Caudovirales,4QNXH@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_72430_10 1051675.G0YQH7_9CAUD 2.18e-112 343.0 4QGGR@10239|Viruses,4QZHR@35237|dsDNA viruses no RNA stage,4QUGZ@28883|Caudovirales,4QNY3@10744|Podoviridae 10744|Podoviridae S viral capsid - - - - - - - - - - - - - k59_527402_1 1500890.JQNL01000001_gene3314 5.3e-21 103.0 COG0845@1|root,COG4733@1|root,COG0845@2|Bacteria,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria,1RNFD@1236|Gammaproteobacteria,1XABA@135614|Xanthomonadales 135614|Xanthomonadales M Phage-related protein, tail component - - - - - - - - - - - - DUF1983,Phage-tail_3 k59_213849_1 1563661.A0A097PAP3_9CAUD 2.13e-62 217.0 4QAKM@10239|Viruses,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_11927_2 1618243.A0A0C5IAV0_9CIRC 1.85e-43 157.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_605661_1 1086011.HJ01_02729 2.3e-10 61.6 COG4696@1|root,COG4696@2|Bacteria,4NNW2@976|Bacteroidetes,1I23U@117743|Flavobacteriia,2NWAR@237|Flavobacterium 976|Bacteroidetes S Phosphoribosyl-ATP pyrophosphohydrolase - - - - - - - - - - - - PRA-PH k59_50106_2 1692242.A0A0K1RL37_9CIRC 2.69e-64 209.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_585272_1 1414738.V5UQL8_9CAUD 2.14e-116 363.0 4QGA5@10239|Viruses,4QURD@35237|dsDNA viruses no RNA stage,4QT9N@28883|Caudovirales,4QP47@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_342351_1 1618256.A0A0C5IM93_9CIRC 1.52e-08 55.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_31280_1 1166018.FAES_0827 1.45e-11 67.0 COG0468@1|root,COG0468@2|Bacteria,4NEXT@976|Bacteroidetes,47K6D@768503|Cytophagia 976|Bacteroidetes L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA - - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA k59_357980_1 1234888.K0A2J2_9VIRU 7.08e-53 181.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_257912_1 1410619.SRDD_27170 2.69e-10 62.8 COG1396@1|root,COG2932@1|root,COG1396@2|Bacteria,COG2932@2|Bacteria,1PIRG@1224|Proteobacteria,1S499@1236|Gammaproteobacteria,405PW@613|Serratia 1236|Gammaproteobacteria K Peptidase S24-like prtR3 - - - - - - - - - - - HTH_3,Peptidase_S24 k59_135147_1 1120985.AUMI01000001_gene2164 2.64e-10 67.0 COG5281@1|root,COG5281@2|Bacteria,1TPWF@1239|Firmicutes,4H3NF@909932|Negativicutes 909932|Negativicutes S tape measure - - - - - - - - - - - - - k59_400424_1 272942.RCAP_rcc00964 1.08e-25 118.0 COG4733@1|root,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria,2TV2W@28211|Alphaproteobacteria,1FD1T@1060|Rhodobacter 28211|Alphaproteobacteria S COG4733 Phage-related protein, tail component - - - - - - - - - - - - Phage-tail_3 k59_527440_1 709484.E5DI52_9CAUD 3.6e-09 60.8 4QBA2@10239|Viruses,4QV98@35237|dsDNA viruses no RNA stage,4QPPI@28883|Caudovirales,4QIA3@10662|Myoviridae 10662|Myoviridae S Thymidylate synthase - - - - - - - - - - - - - k59_527440_2 871968.DESME_15505 1.39e-26 104.0 COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,24HF0@186801|Clostridia,261R0@186807|Peptococcaceae 186801|Clostridia F PFAM Cytidine and deoxycytidylate deaminase zinc-binding region comEB - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 k59_547754_1 650150.ERH_0610 6.21e-16 86.3 COG2369@1|root,COG2369@2|Bacteria,1U6KJ@1239|Firmicutes,3VRMN@526524|Erysipelotrichia 526524|Erysipelotrichia S Phage Mu protein F like protein - - - - - - - - - - - - Phage_Mu_F k59_115445_2 195253.Syn6312_2561 1.4e-48 168.0 COG0338@1|root,COG0338@2|Bacteria,1G2H8@1117|Cyanobacteria,1H380@1129|Synechococcus 1117|Cyanobacteria L PFAM D12 class N6 adenine-specific DNA methyltransferase dmnB - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 k59_115445_3 290397.Adeh_3627 1.13e-24 98.2 COG1403@1|root,COG1403@2|Bacteria,1NI5K@1224|Proteobacteria 1224|Proteobacteria V HNH nucleases - - - - - - - - - - - - - k59_263946_1 1347342.BN863_6930 1.01e-16 82.8 COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,1HXGF@117743|Flavobacteriia 976|Bacteroidetes F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrd - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_lgC,Ribonuc_red_lgN k59_386373_2 1262513.K7Z9I9_9CAUD 3.87e-15 76.3 4QBYC@10239|Viruses,4R0KA@35237|dsDNA viruses no RNA stage,4QSRI@28883|Caudovirales,4QJGA@10662|Myoviridae 10662|Myoviridae S lyase activity - - - - - - - - - - - - - k59_632419_1 264462.Bd1130 9.82e-07 57.0 COG3209@1|root,COG3209@2|Bacteria,1QY1R@1224|Proteobacteria,43C93@68525|delta/epsilon subdivisions,2MUT2@213481|Bdellovibrionales,2X7JI@28221|Deltaproteobacteria 213481|Bdellovibrionales M cell wall surface anchor family protein - - - - - - - - - - - - Peptidase_S74 k59_201112_1 1308863.U5J9Q1_9CAUD 1.26e-14 72.4 4QCFK@10239|Viruses,4QXH5@35237|dsDNA viruses no RNA stage,4QPB3@28883|Caudovirales,4QN18@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_427101_1 909613.UO65_2975 2.48e-25 106.0 COG0285@1|root,COG0285@2|Bacteria,2IB4Z@201174|Actinobacteria,4EAJA@85010|Pseudonocardiales 201174|Actinobacteria H Mur ligase middle domain - - - - - - - - - - - - Mur_ligase_M k59_240711_1 1556290.A0A0A0RM00_9CAUD 1.03e-61 208.0 4QAXQ@10239|Viruses,4QRFY@28883|Caudovirales,4QM52@10699|Siphoviridae 10699|Siphoviridae S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor - - - - - - - - - - - - - k59_324184_2 102129.Lepto7375DRAFT_7192 1.35e-24 112.0 COG0467@1|root,COG1467@1|root,COG0467@2|Bacteria,COG1467@2|Bacteria 2|Bacteria L DNA replication initiation - - - - - - - - - - - - AAA_11,AAA_12,AAA_25,DUF3320,DUF3987,DUF4011 k59_387381_1 348824.LPU83_0595 3.31e-16 84.0 COG3740@1|root,COG3740@2|Bacteria,1QVIJ@1224|Proteobacteria,2TVIM@28211|Alphaproteobacteria,4BNVZ@82115|Rhizobiaceae 28211|Alphaproteobacteria S Phage capsid family - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_570172_1 1237149.C900_05366 1.01e-10 67.4 COG3740@1|root,COG3740@2|Bacteria,4NDXV@976|Bacteroidetes,47V54@768503|Cytophagia 976|Bacteroidetes S Phage prohead protease, HK97 family - - - - - - - - - - - - Peptidase_S78 k59_509093_2 1406793.U5PXJ2_9CAUD 3.25e-23 90.5 4QAZF@10239|Viruses,4QUTY@35237|dsDNA viruses no RNA stage,4QPH6@28883|Caudovirales,4QM17@10699|Siphoviridae 10699|Siphoviridae S Protein of unknwon function (DUF3310) - - - - - - - - - - - - - k59_37402_1 1692244.A0A0K1RLR5_9CIRC 2.17e-11 63.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_37402_2 1788454.A0A190WHE4_9CIRC 8.59e-41 146.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_611342_2 1385658.U5KNR1_9VIRU 7.04e-41 147.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_472620_1 396588.Tgr7_0386 4.07e-64 224.0 COG1345@1|root,COG1345@2|Bacteria,1QZZ9@1224|Proteobacteria 1224|Proteobacteria N Prophage tail length tape measure protein - - - - - - - - - - - - TMP_2 k59_472620_3 1101190.ARWB01000001_gene646 4.45e-14 73.2 2E3EW@1|root,32YDU@2|Bacteria,1NFHT@1224|Proteobacteria,2VGTE@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - Phage_tail_3 k59_411094_3 1165094.RINTHH_3920 6.37e-49 172.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_411094_6 1385658.U5KPZ6_9VIRU 2.29e-181 525.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_1161_1 360911.EAT1b_1551 1.33e-15 85.1 COG4942@1|root,COG4942@2|Bacteria,1VJ3D@1239|Firmicutes,4ITEE@91061|Bacilli 91061|Bacilli D Peptidase family M23 - - - - - - - - - - - - Peptidase_M23 k59_534235_2 1618248.A0A0C5IB82_9CIRC 2.57e-15 82.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_431435_1 1121344.JHZO01000006_gene1818 6.89e-16 79.7 28MKK@1|root,2ZAWR@2|Bacteria,1UYAT@1239|Firmicutes,24GI2@186801|Clostridia,3WR2E@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - RNA_helicase,Viral_Rep k59_164918_1 1986029.Q9MBM8_9VIRU 1.27e-58 204.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_452314_1 1121286.AUMT01000001_gene60 1.79e-46 169.0 29FGV@1|root,302EG@2|Bacteria,4PJGH@976|Bacteroidetes,1I8PA@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_472959_11 880073.Calab_1470 2.9e-54 180.0 COG0270@1|root,COG0270@2|Bacteria 2|Bacteria L DNA (cytosine-5-)-methyltransferase activity dcm - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_83244_2 1236000.L0ASY2_9CAUD 1.61e-68 226.0 4QC5D@10239|Viruses,4QVY9@35237|dsDNA viruses no RNA stage,4QPVU@28883|Caudovirales,4QIJW@10662|Myoviridae 10662|Myoviridae S Protein of unknown function (DUF2800) - - - - - - - - - - - - - k59_513991_1 449447.MAE_62330 1.45e-26 108.0 28K7U@1|root,2Z9VT@2|Bacteria,1G5VD@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - k59_21558_1 631362.Thi970DRAFT_01654 8.72e-150 451.0 COG0749@1|root,COG0749@2|Bacteria,1MVWW@1224|Proteobacteria,1SFM4@1236|Gammaproteobacteria 1236|Gammaproteobacteria L DNA polymerase family A - - - - - - - - - - - - DNA_pol_A k59_83246_2 990285.RGCCGE502_05005 0.00026 50.8 COG1475@1|root,COG4725@1|root,COG1475@2|Bacteria,COG4725@2|Bacteria,1R553@1224|Proteobacteria,2TRP6@28211|Alphaproteobacteria,4BGSK@82115|Rhizobiaceae 28211|Alphaproteobacteria KT Belongs to the MT-A70-like family - - - - - - - - - - - - MT-A70,ParBc k59_390801_1 1000565.METUNv1_01675 1.83e-14 79.3 COG4733@1|root,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria,2VJEP@28216|Betaproteobacteria 28216|Betaproteobacteria NT Phage-related protein, tail - - - - - - - - - - - - DUF1983,Phage-tail_3 k59_123901_1 530564.Psta_1055 2.32e-09 63.9 COG0841@1|root,COG0841@2|Bacteria,2IYJA@203682|Planctomycetes 203682|Planctomycetes V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k59_126873_1 397290.C810_05192 1.24e-18 82.4 29VAC@1|root,30GQG@2|Bacteria,1UGFG@1239|Firmicutes,24P9A@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - DUF1523 k59_126873_2 1123009.AUID01000002_gene2075 2.86e-09 61.6 COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,24HEX@186801|Clostridia,2691D@186813|unclassified Clostridiales 186801|Clostridia F Essential for recycling GMP and indirectly, cGMP gmk - 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_kin k59_188365_5 1089453.GOSPT_007_00440 6.98e-26 108.0 COG0515@1|root,COG0515@2|Bacteria,2IMGY@201174|Actinobacteria,4GC2T@85026|Gordoniaceae 201174|Actinobacteria KLT Domain of unknown function (DUF4352) - - - - - - - - - - - - DUF4352 k59_413882_1 536232.CLM_2667 1.64e-57 194.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,36DK9@31979|Clostridiaceae 186801|Clostridia L snf2 family - - - - - - - - - - - - Helicase_C,SNF2_N k59_270220_4 765420.OSCT_3182 3.94e-20 89.7 COG2189@1|root,COG2189@2|Bacteria,2G7K2@200795|Chloroflexi,3756B@32061|Chloroflexia 32061|Chloroflexia L DNA methylase - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_372704_3 714943.Mucpa_4926 6.05e-11 65.5 COG3378@1|root,COG3378@2|Bacteria,4NNKX@976|Bacteroidetes,1ISH6@117747|Sphingobacteriia 976|Bacteroidetes L Bifunctional DNA primase/polymerase, N-terminal - - - - - - - - - - - - Prim-Pol k59_4095_1 1618248.A0A0C5IB82_9CIRC 1.92e-52 175.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_641079_1 1121895.Q765_15005 4.91e-09 64.3 2EAST@1|root,334US@2|Bacteria,4NRGD@976|Bacteroidetes,1I583@117743|Flavobacteriia,2NU1I@237|Flavobacterium 976|Bacteroidetes - - - - - - - - - - - - - - - k59_538416_2 1125712.HMPREF1316_1543 1.34e-12 67.0 COG4570@1|root,COG4570@2|Bacteria,2HWEZ@201174|Actinobacteria,4CYBJ@84998|Coriobacteriia 84998|Coriobacteriia L Endodeoxyribonuclease RusA - - - - - - - - - - - - RusA k59_250769_1 1173762.S4TP20_9CAUD 2.23e-40 149.0 4QB3X@10239|Viruses,4QWKP@35237|dsDNA viruses no RNA stage,4QPEE@28883|Caudovirales,4QNCI@10744|Podoviridae 10744|Podoviridae S VWA-like domain (DUF2201) - - - - - - - - - - - - - k59_65501_2 1234888.K0A2J2_9VIRU 3.1e-131 395.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_542781_2 1122991.BAIZ01000025_gene1859 6.75e-63 201.0 COG0270@1|root,COG0270@2|Bacteria,4NJPP@976|Bacteroidetes,2FKYT@200643|Bacteroidia 976|Bacteroidetes H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_542781_3 755731.Clo1100_1143 9.2e-07 52.4 COG0270@1|root,COG0270@2|Bacteria,1TPNE@1239|Firmicutes,24B1A@186801|Clostridia,36JFQ@31979|Clostridiaceae 186801|Clostridia H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_150924_1 428125.CLOLEP_01422 1.41e-25 110.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia,3WN92@541000|Ruminococcaceae 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_646032_1 1692253.A0A0K1RLM4_9CIRC 3.12e-61 209.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_440030_1 1509405.GV67_04245 3.09e-24 97.8 COG3023@1|root,COG3023@2|Bacteria,1N032@1224|Proteobacteria,2U6P9@28211|Alphaproteobacteria,4BHDN@82115|Rhizobiaceae 28211|Alphaproteobacteria V N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - Amidase_2,PG_binding_1 k59_355056_1 997346.HMPREF9374_0725 1.94e-26 111.0 COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,4HGWM@91061|Bacilli,27B6J@186824|Thermoactinomycetaceae 91061|Bacilli LU DNA recombination-mediator protein A dprA GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - ko:K04096 - - - - ko00000 - - - DNA_processg_A k59_396884_1 382359.Q0QZC0_BPSYS 1.71e-11 63.9 4QEX9@10239|Viruses,4QZVS@35237|dsDNA viruses no RNA stage,4QSTV@28883|Caudovirales,4QIUZ@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_652035_1 553175.POREN0001_0070 2.69e-34 134.0 COG1187@1|root,COG1187@2|Bacteria,4NEE1@976|Bacteroidetes,2FP7M@200643|Bacteroidia,22WKX@171551|Porphyromonadaceae 976|Bacteroidetes J Belongs to the pseudouridine synthase RsuA family rluB - 5.4.99.22 ko:K06178 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k59_463901_2 1122599.AUGR01000001_gene288 1.25e-42 145.0 COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,1SQ0T@1236|Gammaproteobacteria 1236|Gammaproteobacteria L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_96920_1 61647.LG71_06515 3.97e-65 207.0 COG1475@1|root,COG1475@2|Bacteria,1R5VN@1224|Proteobacteria,1RZ7C@1236|Gammaproteobacteria 1236|Gammaproteobacteria K ParB-like nuclease domain ybdM - - - - - - - - - - - ParBc k59_12602_2 1609634.A0A0C5ANA6_9VIRU 4.41e-05 50.4 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_196258_1 1504822.CCNO01000015_gene594 1.03e-105 331.0 COG0553@1|root,COG0863@1|root,COG0553@2|Bacteria,COG0863@2|Bacteria 2|Bacteria L N-4 methylation of cytosine - - - - - - - - - - - - Helicase_C,N6_N4_Mtase,SNF2_N k59_278268_1 742741.HMPREF9475_00404 0.000299 48.9 29R5M@1|root,30C6X@2|Bacteria,1V4R3@1239|Firmicutes,249E1@186801|Clostridia,2228Z@1506553|Lachnoclostridium 186801|Clostridia S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - - k59_259052_1 402612.FP0810 1.41e-48 161.0 COG3023@1|root,COG3023@2|Bacteria,4NQ2J@976|Bacteroidetes,1I3X8@117743|Flavobacteriia,2NXVJ@237|Flavobacterium 976|Bacteroidetes V N-acetylmuramoyl-L-alanine amidase - - 3.5.1.28 ko:K01447 - - R04112 RC00064,RC00141 ko00000,ko01000 - - - Amidase_2 k59_214632_4 1038862.KB893851_gene6274 7.85e-08 54.3 2E0C4@1|root,32VZ6@2|Bacteria,1R26E@1224|Proteobacteria,2TZBD@28211|Alphaproteobacteria,3K6Z8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_343525_1 521097.Coch_0883 1.7e-46 165.0 COG0270@1|root,COG0270@2|Bacteria,4NVMZ@976|Bacteroidetes,1IEAJ@117743|Flavobacteriia,1EQWM@1016|Capnocytophaga 976|Bacteroidetes L C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_115032_2 266779.Meso_1239 2.49e-14 76.6 COG3409@1|root,COG3409@2|Bacteria,1NWZG@1224|Proteobacteria,2US3G@28211|Alphaproteobacteria,43QVQ@69277|Phyllobacteriaceae 28211|Alphaproteobacteria M Pfam:DUF3380 - - - - - - - - - - - - Muraidase k59_201348_1 151528.L0CQP2_9CAUD 1.46e-08 63.5 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QNBD@10744|Podoviridae 10744|Podoviridae S outer membrane - - - - - - - - - - - - - k59_303855_3 107636.JQNK01000008_gene4031 4.58e-29 116.0 28J3M@1|root,2Z8ZT@2|Bacteria,1Q2A4@1224|Proteobacteria,2TSHZ@28211|Alphaproteobacteria,370YR@31993|Methylocystaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - PDDEXK_1 k59_323511_1 1047013.AQSP01000118_gene1252 3.91e-47 166.0 COG0433@1|root,COG0433@2|Bacteria 2|Bacteria S helicase activity - - - - - - - - - - - - - k59_141304_1 1054460.SPPN_00145 2.36e-07 57.0 2CWXD@1|root,32T0J@2|Bacteria,1V83I@1239|Firmicutes,4HPQE@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k59_590597_1 1692255.A0A0K1RL52_9CIRC 1.97e-67 219.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_141332_1 1196322.A370_03126 1.67e-38 139.0 28JYX@1|root,2Z9P3@2|Bacteria,1V1YH@1239|Firmicutes,24KAB@186801|Clostridia 186801|Clostridia S Domain of unknown function (DUF4343) - - - - - - - - - - - - DUF4343 k59_182846_1 649747.HMPREF0083_01683 3.04e-19 91.7 COG4373@1|root,COG4373@2|Bacteria,1TQNK@1239|Firmicutes,4HDES@91061|Bacilli,26WPR@186822|Paenibacillaceae 91061|Bacilli S Mu-like prophage FluMu protein gp28 gp17a - - - - - - - - - - - Terminase_6,Terminase_6C k59_386678_1 1158614.I592_02352 8.48e-47 166.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4HC9V@91061|Bacilli,4B1WH@81852|Enterococcaceae 91061|Bacilli KL SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,ResIII,SNF2_N k59_159201_1 1506572.A0A097ZPG0_9CIRC 5.66e-17 85.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_282591_1 1492922.GY26_16080 5.98e-87 281.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,1RP8Z@1236|Gammaproteobacteria,1J8Y8@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_323611_1 428125.CLOLEP_01399 3.36e-39 135.0 29YRZ@1|root,30KMY@2|Bacteria,1V4Y4@1239|Firmicutes,24HPY@186801|Clostridia,3WNNS@541000|Ruminococcaceae 186801|Clostridia S Protein of unknown function (DUF2800) - - - - - - - - - - - - DUF2800 k59_323611_2 428125.CLOLEP_01398 7.45e-33 116.0 2CGGB@1|root,32UNH@2|Bacteria,1VD9W@1239|Firmicutes,24MWC@186801|Clostridia,3WPKG@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_469468_1 1234888.K0A2J2_9VIRU 1.57e-38 146.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_115841_1 272560.BPSL1143 2.65e-25 107.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2VNHP@28216|Betaproteobacteria,1K7BW@119060|Burkholderiaceae 28216|Betaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_182915_1 1234888.K0A2J2_9VIRU 9.51e-58 196.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_17940_1 1196835.A458_06950 1.73e-48 177.0 COG1511@1|root,COG5281@1|root,COG1511@2|Bacteria,COG5281@2|Bacteria,1MX2R@1224|Proteobacteria,1TAY6@1236|Gammaproteobacteria,1Z3JC@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria D tape measure protein - - - - - - - - - - - - - k59_141399_1 634499.EpC_20850 3.94e-29 114.0 COG0847@1|root,COG0847@2|Bacteria,1R9YS@1224|Proteobacteria,1S23K@1236|Gammaproteobacteria 1236|Gammaproteobacteria L 3' exoribonuclease, RNase T-like - - - - - - - - - - - - DUF5051 k59_282623_1 585502.HMPREF0645_2609 2.01e-59 207.0 COG0553@1|root,COG0863@1|root,COG0553@2|Bacteria,COG0863@2|Bacteria,4NHHF@976|Bacteroidetes,2FRI5@200643|Bacteroidia 976|Bacteroidetes KL DNA methylase - - - - - - - - - - - - Helicase_C,N6_N4_Mtase,SNF2_N k59_241018_1 557598.LHK_01799 1.36e-84 265.0 COG0582@1|root,COG0582@2|Bacteria,1NWGS@1224|Proteobacteria,2VKWM@28216|Betaproteobacteria,2KR09@206351|Neisseriales 206351|Neisseriales L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_integrase k59_164459_1 478741.JAFS01000002_gene208 3.79e-23 99.8 COG0675@1|root,COG0675@2|Bacteria 2|Bacteria L Transposase, IS605 OrfB family - - - ko:K07496 - - - - ko00000 - - - - k59_308015_2 1443665.JACA01000034_gene2489 5.31e-06 50.4 COG1595@1|root,COG1595@2|Bacteria,4NU6U@976|Bacteroidetes,1I42V@117743|Flavobacteriia,2YH0U@290174|Aquimarina 976|Bacteroidetes K Sigma-70, region 4 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k59_472444_2 391038.Bphy_1919 4.14e-11 64.3 COG2197@1|root,COG2197@2|Bacteria,1NA3X@1224|Proteobacteria,2VWX0@28216|Betaproteobacteria,1KAW7@119060|Burkholderiaceae 28216|Betaproteobacteria KT phage-related functions and prophages - - - - - - - - - - - - HNH_3 k59_369586_2 1122201.AUAZ01000017_gene2950 7.07e-76 239.0 COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,1RY1X@1236|Gammaproteobacteria,46BED@72275|Alteromonadaceae 1236|Gammaproteobacteria S associated with various cellular activities - - - - - - - - - - - - AAA,AAA_5 k59_615849_4 1122201.AUAZ01000017_gene2949 8.52e-73 239.0 COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,1RXX2@1236|Gammaproteobacteria,46B9P@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative metallopeptidase domain - - - - - - - - - - - - DUF2201,DUF2201_N k59_410771_1 1173709.M3VMK9_9CIRC 1.54e-68 214.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_492739_11 620914.JH621271_gene1708 3.1e-06 48.9 2EEZE@1|root,338SK@2|Bacteria,4NVC1@976|Bacteroidetes,1I5BS@117743|Flavobacteriia,2YM2A@290174|Aquimarina 976|Bacteroidetes - - - - - - - - - - - - - - - k59_492739_22 243274.THEMA_04875 3.37e-85 268.0 COG0468@1|root,COG0468@2|Bacteria,2GBXS@200918|Thermotogae 200918|Thermotogae L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA k59_492739_23 357276.EL88_11480 2.21e-80 261.0 COG1061@1|root,COG1061@2|Bacteria,4NECV@976|Bacteroidetes,2FN7J@200643|Bacteroidia,4AN2T@815|Bacteroidaceae 976|Bacteroidetes L helicase superfamily c-terminal domain - - - ko:K19789 - - - - ko00000,ko03400 - - - Helicase_C,QSregVF_b,ResIII k59_472760_1 1121468.AUBR01000020_gene2866 1.83e-54 178.0 COG0047@1|root,COG0047@2|Bacteria,1TP1B@1239|Firmicutes,24A2E@186801|Clostridia,42EVD@68295|Thermoanaerobacterales 186801|Clostridia F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purQ - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - GATase_5 k59_472760_2 1235811.HMPREF0653_01693 2.17e-06 55.1 COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,4NETY@976|Bacteroidetes,2FM2Z@200643|Bacteroidia 976|Bacteroidetes F Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate purL - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS_C,GATase_5 k59_636674_1 142661.REP_CACV 1.51e-31 125.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_390487_1 1094508.Tsac_2371 2.41e-42 148.0 COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia,42FTY@68295|Thermoanaerobacterales 186801|Clostridia V Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides macB - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k59_291106_3 1121451.DESAM_20350 2.2e-28 129.0 COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,1N2VJ@1224|Proteobacteria,43C4Q@68525|delta/epsilon subdivisions,2WREQ@28221|Deltaproteobacteria 28221|Deltaproteobacteria M PFAM Glycosyl transferase family 2 - - - - - - - - - - - - Glyco_trans_4_4,Glycos_transf_1,Glycos_transf_2 k59_332840_1 2003327.CAPSD_BPCHP 6.15e-14 81.6 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_352016_1 412419.BDU_550 3.33e-12 70.5 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2J5FM@203691|Spirochaetes 203691|Spirochaetes L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_127070_1 317936.Nos7107_2657 4.44e-27 114.0 COG2189@1|root,COG2189@2|Bacteria,1G2XK@1117|Cyanobacteria,1HU8N@1161|Nostocales 1117|Cyanobacteria L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.72 ko:K00571,ko:K07319 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_517540_1 1385658.U5KPZ6_9VIRU 6.57e-50 175.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_270470_1 1380354.JIAN01000008_gene3362 1.83e-33 142.0 COG3291@1|root,COG3420@1|root,COG3291@2|Bacteria,COG3420@2|Bacteria,2GN7G@201174|Actinobacteria 201174|Actinobacteria P PFAM PKD domain containing protein - - - - - - - - - - - - DUF5122,Laminin_G_3,Malectin,PKD k59_435417_1 421052.F945_01971 9.04e-16 82.0 28JXH@1|root,2ZA3Z@2|Bacteria,1R8CZ@1224|Proteobacteria,1TME3@1236|Gammaproteobacteria,3NMYG@468|Moraxellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - RecT k59_517985_1 1788455.A0A190WHF5_9CIRC 2.27e-56 188.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_333279_1 1692259.A0A0K1RL59_9CIRC 1.69e-13 77.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_435896_1 1234888.K0A2J2_9VIRU 3.01e-61 206.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_251018_1 203119.Cthe_2488 8.81e-09 67.0 COG5281@1|root,COG5281@2|Bacteria,1TPWF@1239|Firmicutes,24A8R@186801|Clostridia,3WN6S@541000|Ruminococcaceae 186801|Clostridia S tape measure - - - - - - - - - - - - - k59_641401_2 55529.EKX55560 1.1e-11 64.7 COG0124@1|root,KOG1936@2759|Eukaryota 2759|Eukaryota J Histidyl-trna synthetase - GO:0003674,GO:0003824,GO:0004812,GO:0004821,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006427,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009536,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 3.6.4.13,6.1.1.21 ko:K01892,ko:K14442 ko00970,ko03018,map00970,map03018 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03019 - - - HGTP_anticodon,tRNA-synt_His k59_393759_1 1391647.AVSV01000022_gene2570 7.34e-20 102.0 COG5283@1|root,COG5412@1|root,COG5283@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,247QT@186801|Clostridia,36E7F@31979|Clostridiaceae 186801|Clostridia M tail tape measure protein - - - - - - - - - - - - PhageMin_Tail k59_24631_1 1151292.QEW_1348 8.01e-12 74.3 COG5281@1|root,COG5281@2|Bacteria,1TPWF@1239|Firmicutes,24A8R@186801|Clostridia,25SJX@186804|Peptostreptococcaceae 186801|Clostridia S tape measure - - - - - - - - - - - - PhageMin_Tail k59_87054_2 391038.Bphy_1919 1.38e-19 87.4 COG2197@1|root,COG2197@2|Bacteria,1NA3X@1224|Proteobacteria,2VWX0@28216|Betaproteobacteria,1KAW7@119060|Burkholderiaceae 28216|Betaproteobacteria KT phage-related functions and prophages - - - - - - - - - - - - HNH_3 k59_578561_1 688246.Premu_2041 0.000256 50.8 COG1595@1|root,COG1595@2|Bacteria,4NQH8@976|Bacteroidetes,2FT5W@200643|Bacteroidia 976|Bacteroidetes K DNA-templated transcription, initiation - - - - - - - - - - - - - k59_208317_1 145579.CAPSD_BPPHM 3.96e-53 193.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_624823_1 1331060.RLDS_16020 2.57e-45 164.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2TSDW@28211|Alphaproteobacteria,2K42P@204457|Sphingomonadales 204457|Sphingomonadales S Terminase - - - - - - - - - - - - Terminase_1 k59_524424_1 1122998.AUHZ01000011_gene560 7.96e-13 76.3 COG0584@1|root,COG0584@2|Bacteria 2|Bacteria C glycerophosphodiester phosphodiesterase activity - - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD k59_109090_3 1732201.A0A0N9N7I3_9CIRC 1.35e-11 72.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_70517_1 310539.Q5G7P7_9CAUD 4.54e-48 160.0 4QGB5@10239|Viruses,4QXR2@35237|dsDNA viruses no RNA stage,4QSQD@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_624855_1 10742.Q9MCV7_BPHK0 8.99e-52 182.0 4QBV3@10239|Viruses,4QW0W@35237|dsDNA viruses no RNA stage,4QPPJ@28883|Caudovirales,4QKW5@10699|Siphoviridae 10699|Siphoviridae S Phage Terminase - - - - - - - - - - - - - k59_441743_1 1122201.AUAZ01000017_gene2949 6.34e-33 127.0 COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,1RXX2@1236|Gammaproteobacteria,46B9P@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative metallopeptidase domain - - - - - - - - - - - - DUF2201,DUF2201_N k59_212074_1 1121286.AUMT01000001_gene51 1.38e-09 67.8 COG5280@1|root,COG5280@2|Bacteria,4NKDN@976|Bacteroidetes,1I134@117743|Flavobacteriia 976|Bacteroidetes D Phage tail tape measure protein, TP901 family - - - - - - - - - - - - PhageMin_Tail k59_92922_1 1397284.AYMN01000003_gene1296 1.92e-24 111.0 COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,1RNE0@1236|Gammaproteobacteria,40545@613|Serratia 1236|Gammaproteobacteria L Pfam:DUF4102 - - - - - - - - - - - - Arm-DNA-bind_3,Phage_int_SAM_3,Phage_integrase k59_92923_1 1788447.A0A190WHJ9_9CIRC 1.6e-28 114.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_194322_1 481448.Minf_0497 0.000103 53.1 COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,46ZHJ@74201|Verrucomicrobia,37H45@326457|unclassified Verrucomicrobia 74201|Verrucomicrobia M Glycosyltransferase like family 2 - - - - - - - - - - - - Glyco_trans_1_4,Glycos_transf_2 k59_419867_2 891968.Anamo_0742 4.17e-44 171.0 COG3378@1|root,COG3378@2|Bacteria,3TBFP@508458|Synergistetes 508458|Synergistetes S D5 N terminal like - - - ko:K06919 - - - - ko00000 - - - D5_N,Pox_D5 k59_419867_3 1203605.HMPREF1531_02519 9.03e-09 61.6 COG0358@1|root,COG0358@2|Bacteria,2GJFX@201174|Actinobacteria,4DN6K@85009|Propionibacteriales 201174|Actinobacteria L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,DnaG_DnaB_bind,Toprim_4,Toprim_N,zf-CHC2 k59_356644_1 864069.MicloDRAFT_00037670 6.28e-29 123.0 COG1061@1|root,COG1061@2|Bacteria,1N52C@1224|Proteobacteria,2U3TE@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Type III restriction enzyme, res subunit - - - - - - - - - - - - Helicase_C,ResIII k59_296969_1 634994.GCWU000323_01816 2.21e-27 111.0 COG1743@1|root,COG1743@2|Bacteria 2|Bacteria L DNA methylAse - - - ko:K07448 - - - - ko00000,ko02048 - - - HSDR_N_2,MethyltransfD12,Mrr_cat,N6_N4_Mtase k59_52471_1 644966.Tmar_1145 1.35e-31 125.0 COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,247QQ@186801|Clostridia,3WD2S@538999|Clostridiales incertae sedis 186801|Clostridia L Phage integrase, N-terminal SAM-like domain xerD - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase k59_630818_2 936136.ARRT01000006_gene5340 5.6e-79 260.0 COG1783@1|root,COG1783@2|Bacteria,1RAGC@1224|Proteobacteria,2U6JF@28211|Alphaproteobacteria,4BID4@82115|Rhizobiaceae 28211|Alphaproteobacteria S phage Terminase large subunit - - - - - - - - - - - - - k59_609519_1 1325372.N0DPG8_9CAUD 1.19e-21 95.1 4QBHW@10239|Viruses,4QW8N@35237|dsDNA viruses no RNA stage,4QTT7@28883|Caudovirales,4QJZQ@10662|Myoviridae 10662|Myoviridae S sequence-specific DNA binding transcription factor activity - - - - - - - - - - - - - k59_261948_1 1040987.AZUY01000006_gene1805 9.75e-59 205.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2TSDW@28211|Alphaproteobacteria,43K5X@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_180858_2 1236689.MMALV_03740 7.13e-20 85.9 COG0603@1|root,arCOG00039@2157|Archaea,2XTS7@28890|Euryarchaeota,3F2JU@33867|unclassified Euryarchaeota 28890|Euryarchaeota H Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) queC - 6.3.4.20 ko:K06920 ko00790,ko01100,map00790,map01100 - R09978 RC00959 ko00000,ko00001,ko01000,ko03016 - - - QueC k59_101401_1 749414.SBI_08881 2.41e-14 77.0 COG4295@1|root,COG4295@2|Bacteria,2GKXE@201174|Actinobacteria 201174|Actinobacteria K Uncharacterized protein conserved in bacteria (DUF2263) - - - - - - - - - - - - DUF2263 k59_630827_1 1121382.JQKG01000001_gene2517 1.3e-12 72.8 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria 2|Bacteria K chromosome segregation terL - - - - - - - - - - - Terminase_6,Terminase_6C k59_492064_1 1188795.K7ZRM7_9CAUD 1e-19 93.2 4QHMX@10239|Viruses,4QW8C@35237|dsDNA viruses no RNA stage,4QRQS@28883|Caudovirales,4QNWI@10744|Podoviridae 10744|Podoviridae S metallopeptidase activity - - - - - - - - - - - - - k59_553029_1 1692252.A0A0K1RL35_9CIRC 2.7e-47 163.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_609538_1 1094556.MCY_01320 2.74e-58 202.0 COG4643@1|root,COG4643@2|Bacteria,1N08G@1224|Proteobacteria,2U9N8@28211|Alphaproteobacteria,48SYH@772|Bartonellaceae 28211|Alphaproteobacteria S membrane spanning protein Brucella melitensis 16M gi 17987979 ref - - - - - - - - - - - - DUF3987 k59_553038_1 272621.LBA0966 0.000397 46.6 COG1388@1|root,COG1388@2|Bacteria,1W2PN@1239|Firmicutes,4I0F8@91061|Bacilli,3F6G9@33958|Lactobacillaceae 91061|Bacilli M Lysin motif - - - - - - - - - - - - LysM k59_630856_2 1402875.U3TK13_9CAUD 0.00014 45.1 4QD7Q@10239|Viruses,4QWCG@35237|dsDNA viruses no RNA stage,4QPCM@28883|Caudovirales,4QNQT@10744|Podoviridae 10744|Podoviridae S Pfam:Phage_tail_APC - - - - - - - - - - - - - k59_492069_5 875454.BAEW01000002_gene465 6.89e-23 111.0 COG5281@1|root,COG5281@2|Bacteria,1TPWF@1239|Firmicutes,24A8R@186801|Clostridia 186801|Clostridia S tape measure - - - - - - - - - - - - - k59_76228_1 319003.Bra1253DRAFT_07733 2.07e-25 103.0 COG0175@1|root,COG0175@2|Bacteria 2|Bacteria EH sulfate reduction - - - - - - - - - - - - PAPS_reduct k59_76228_2 709986.Deima_3170 3.4e-08 56.6 COG4422@1|root,COG4422@2|Bacteria 2|Bacteria F Protein of unknown function (DUF5131) - - - - - - - - - - - - DUF5131 k59_121478_3 1206558.I7LHB5_9CAUD 9.16e-08 56.2 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QI82@10662|Myoviridae 10662|Myoviridae S virus tail, fiber - GO:0005575,GO:0019012 - - - - - - - - - - - k59_368137_2 673375.C9EHC8_9CAUD 1.03e-20 93.2 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QKNE@10699|Siphoviridae 10699|Siphoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_121522_1 1122201.AUAZ01000017_gene2960 1.09e-99 306.0 COG5362@1|root,COG5362@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Terminase_6C k59_368202_3 1480731.X2KUH8_9CAUD 3.33e-09 66.2 4QAK6@10239|Viruses,4QPBY@28883|Caudovirales 28883|Caudovirales S N-acetylmuramoyl-L-alanine amidase activity - GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0008150,GO:0016032,GO:0016787,GO:0016798,GO:0019012,GO:0019058,GO:0019062,GO:0022610,GO:0044403,GO:0044406,GO:0044409,GO:0044411,GO:0044419,GO:0044423,GO:0044650,GO:0051701,GO:0051704,GO:0051828,GO:0051830,GO:0085027,GO:0098015,GO:0098024 - - - - - - - - - - - k59_224094_1 1618258.A0A0C5I9K3_9CIRC 2.88e-18 86.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_224094_4 1618236.A0A0C5IB23_9CIRC 1.37e-15 80.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_60083_7 1609634.A0A0C5AFV4_9VIRU 2.9e-90 292.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_368359_1 744985.HIMB59_00014240 1.63e-40 149.0 COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2TRFY@28211|Alphaproteobacteria,4BPTP@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase k59_533530_1 242861.Q6UYH2_9CAUD 5.77e-15 80.1 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QKNE@10699|Siphoviridae 10699|Siphoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_513032_3 1449049.JONW01000013_gene4764 8.42e-19 80.5 COG3772@1|root,COG3772@2|Bacteria,1PFG5@1224|Proteobacteria,2V4QB@28211|Alphaproteobacteria,2KJDV@204458|Caulobacterales 204458|Caulobacterales S lysozyme - - - - - - - - - - - - Phage_lysozyme k59_307779_1 666509.RCA23_c22890 4.22e-15 84.0 COG5545@1|root,COG5545@2|Bacteria,1MVGK@1224|Proteobacteria,2U0ID@28211|Alphaproteobacteria 28211|Alphaproteobacteria L virulence-associated E family protein - - - - - - - - - - - - Prim-Pol,Toprim_3,VirE k59_225877_1 1618248.A0A0C5IB82_9CIRC 4.92e-10 61.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_295_1 291607.MREP_SCSVF 9.48e-12 73.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_166930_1 756272.Plabr_0094 8.8e-10 68.9 COG0187@1|root,COG0187@2|Bacteria,2IWXP@203682|Planctomycetes 203682|Planctomycetes L COG0187 Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) B subunit - - 5.99.1.3 ko:K02470,ko:K02622 - - - - ko00000,ko01000,ko02048,ko03032,ko03036,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim k59_351347_2 1151126.AQYI01000007_gene1539 1.73e-50 165.0 2C5J1@1|root,3067M@2|Bacteria,2IKFX@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_516437_1 1541887.A0A097P485_9CAUD 8.66e-24 103.0 4QB5I@10239|Viruses,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_372083_2 411464.DESPIG_02220 7.12e-13 75.5 COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,42MEI@68525|delta/epsilon subdivisions,2WJEG@28221|Deltaproteobacteria,2M88F@213115|Desulfovibrionales 28221|Deltaproteobacteria E TIGRFAM asparagine synthase (glutamine-hydrolyzing) - - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 k59_146714_1 1224164.B843_01055 1.46e-05 53.5 COG0419@1|root,COG0791@1|root,COG3953@1|root,COG5412@1|root,COG0419@2|Bacteria,COG0791@2|Bacteria,COG3953@2|Bacteria,COG5412@2|Bacteria,2H75F@201174|Actinobacteria,22N4W@1653|Corynebacteriaceae 201174|Actinobacteria M Tail protein - - - - - - - - - - - - - k59_64541_2 1204521.I7B2R4_9CAUD 5.12e-53 177.0 4QF3X@10239|Viruses,4QWSV@35237|dsDNA viruses no RNA stage,4QT5P@28883|Caudovirales 28883|Caudovirales S oxidoreductase activity - - - - - - - - - - - - - k59_64541_4 562743.JH976435_gene3237 2.53e-10 66.6 COG1199@1|root,COG2176@1|root,COG1199@2|Bacteria,COG2176@2|Bacteria,1TQHQ@1239|Firmicutes,4HB2Y@91061|Bacilli 91061|Bacilli L helicase involved in DNA repair and perhaps also replication dinG - 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - DEAD,Helicase_C_2,RNase_T,ResIII k59_64541_5 1449063.JMLS01000002_gene1415 1.17e-75 277.0 COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,4H9T3@91061|Bacilli,26QTS@186822|Paenibacillaceae 91061|Bacilli L DNA polymerase dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k59_105009_2 1437610.BREU_1253 9.59e-27 112.0 COG3740@1|root,COG3740@2|Bacteria,2HBPZ@201174|Actinobacteria,4CZX1@85004|Bifidobacteriales 201174|Actinobacteria S Caudovirus prohead serine protease - - - ko:K06904 - - - - ko00000 - - - Peptidase_S78 k59_597716_1 1122201.AUAZ01000026_gene1209 3.12e-74 236.0 2C6N9@1|root,32RHI@2|Bacteria,1P488@1224|Proteobacteria,1SUTU@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_597716_3 490913.C4NTD1_9CAUD 2.21e-112 357.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_597716_4 1122201.AUAZ01000017_gene2947 4.01e-78 269.0 COG0749@1|root,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,465DD@72275|Alteromonadaceae 1236|Gammaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity - - - - - - - - - - - - DNA_pol_A k59_597716_5 1236501.BAJU01000001_gene263 2.14e-38 135.0 COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,2U7B5@28211|Alphaproteobacteria,2JS8T@204441|Rhodospirillales 204441|Rhodospirillales F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA dut - 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase k59_597716_7 997829.HMPREF1121_00509 2.65e-13 80.1 COG0507@1|root,COG0507@2|Bacteria,4NDYK@976|Bacteroidetes,2FNT1@200643|Bacteroidia,22WXS@171551|Porphyromonadaceae 976|Bacteroidetes L COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member recD2_2 - 3.1.11.5 ko:K01144 - - - - ko00000,ko01000 - - - AAA_30,UvrD_C_2 k59_228362_1 720554.Clocl_0687 3.26e-05 52.4 COG1403@1|root,COG1403@2|Bacteria,1V178@1239|Firmicutes,24DE2@186801|Clostridia,3WM5B@541000|Ruminococcaceae 186801|Clostridia V HNH endonuclease - - - - - - - - - - - - DUF4373 k59_639608_1 1234888.K0A2J2_9VIRU 8.87e-52 179.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_23509_6 742733.HMPREF9469_05020 2.37e-121 428.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia,221IX@1506553|Lachnoclostridium 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_23509_7 691965.D4P7E5_9CAUD 1.28e-44 148.0 4QEVD@10239|Viruses,4QW84@35237|dsDNA viruses no RNA stage,4QQSX@28883|Caudovirales,4QMU4@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_600936_3 1234679.BN424_1486 9.8e-20 88.2 COG3772@1|root,COG3772@2|Bacteria,1VQ7P@1239|Firmicutes,4ITH9@91061|Bacilli 91061|Bacilli G Phage lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_6845_6 314230.DSM3645_08762 3.8e-42 143.0 COG0629@1|root,COG0629@2|Bacteria,2IZJ8@203682|Planctomycetes 203682|Planctomycetes L Single-stranded DNA-binding protein ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_231140_1 1692249.A0A0K1RL40_9CIRC 1.3e-41 149.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_354002_1 1444310.JANV01000162_gene1198 2.6e-05 51.6 2DC6Z@1|root,2ZD43@2|Bacteria 2|Bacteria S HNH endonuclease - - - - - - - - - - - - HNH_3 k59_46134_1 551895.B5AX97_9CAUD 2.57e-27 110.0 4QBHS@10239|Viruses,4QUVV@35237|dsDNA viruses no RNA stage,4QPT9@28883|Caudovirales,4QJCJ@10662|Myoviridae 10662|Myoviridae S DNA metabolic process - - - - - - - - - - - - - k59_375513_1 870187.Thini_0411 3.83e-26 111.0 2EP1Y@1|root,33GNT@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_107377_1 1133022.I6NPA3_9CAUD 1.1e-28 126.0 4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_171064_2 110457.Q9T140_9CAUD 2.47e-05 50.8 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales,4QNBQ@10744|Podoviridae 10744|Podoviridae S HNH endonuclease - - - - - - - - - - - - - k59_520838_2 1609634.A0A0C5AFV4_9VIRU 6.92e-74 250.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_560329_2 186617.M9M8L2_9VIRU 2.8e-46 170.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_354535_1 485917.Phep_3205 3.36e-06 57.8 COG3291@1|root,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1IS57@117747|Sphingobacteriia 976|Bacteroidetes S C-terminal domain of CHU protein family - - - - - - - - - - - - CHU_C,HYR,SprB k59_336741_1 1117943.SFHH103_01649 3.63e-10 70.9 2DQJ1@1|root,3376F@2|Bacteria,1RKWB@1224|Proteobacteria,2UA4H@28211|Alphaproteobacteria,4BE0C@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - Beta_helix,Pectate_lyase_3 k59_521510_1 743721.Psesu_1179 7.74e-10 62.4 2DSRK@1|root,33H6U@2|Bacteria,1P21N@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_585846_1 662755.CRES_1577 2.86e-10 68.6 COG1961@1|root,COG1961@2|Bacteria,2GMAS@201174|Actinobacteria,22MK3@1653|Corynebacteriaceae 201174|Actinobacteria L Recombinase - - - - - - - - - - - - Recombinase,Resolvase,Zn_ribbon_recom k59_445422_1 103733.JNYO01000029_gene908 1.81e-37 134.0 arCOG05626@1|root,2Z9D9@2|Bacteria,2IIAB@201174|Actinobacteria,4E3RQ@85010|Pseudonocardiales 201174|Actinobacteria - - - - - - - - - - - - - - - k59_50539_1 1385658.U5KPZ6_9VIRU 1.22e-96 296.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_50539_2 1385658.U5KQQ9_9VIRU 5.68e-10 65.1 4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_277852_6 1556290.A0A0A0RSX4_9CAUD 4e-44 159.0 4QBP9@10239|Viruses,4QPQF@28883|Caudovirales,4QMF3@10699|Siphoviridae 10699|Siphoviridae S Domain of unknown function (DUF932) - - - - - - - - - - - - - k59_381111_1 1114179.I2FLP0_9CAUD 1.73e-32 124.0 4QE8X@10239|Viruses,4QYGD@35237|dsDNA viruses no RNA stage,4QRJF@28883|Caudovirales,4QNB2@10744|Podoviridae 10744|Podoviridae S Phage phiEco32-like COOH.NH2 ligase-type 2 - - - - - - - - - - - - - k59_463964_1 1385658.U5KPZ6_9VIRU 2.62e-176 505.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_154775_1 1283300.ATXB01000001_gene650 5.31e-06 55.5 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1XEFJ@135618|Methylococcales 135618|Methylococcales L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_236326_1 929556.Solca_0654 1.66e-14 70.5 COG2131@1|root,COG2131@2|Bacteria,4NM48@976|Bacteroidetes,1IRSP@117747|Sphingobacteriia 976|Bacteroidetes F PFAM Cytidine and deoxycytidylate deaminase zinc-binding region comEB - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 k59_487764_1 749222.Nitsa_1810 1.32e-72 225.0 2C2E9@1|root,32RAA@2|Bacteria,1RF5M@1224|Proteobacteria,433I8@68525|delta/epsilon subdivisions 1224|Proteobacteria - - - - - - - - - - - - - - - k59_97060_1 1034101.G1D1G4_9CAUD 2.74e-10 68.9 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales 28883|Caudovirales S N-methyltransferase activity - - - - - - - - - - - - - k59_565623_2 1609634.A0A0C5ANA6_9VIRU 4.77e-10 65.9 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_264709_1 360910.BAV1283 6.38e-52 179.0 COG0270@1|root,COG0270@2|Bacteria,1NPQG@1224|Proteobacteria,2W1GI@28216|Betaproteobacteria 28216|Betaproteobacteria H C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_508996_1 469382.Hbor_29150 9.63e-26 110.0 arCOG07960@1|root,arCOG07960@2157|Archaea,2Y3GN@28890|Euryarchaeota,23ZIV@183963|Halobacteria 183963|Halobacteria - - - - - - - - - - - - - - - k59_18382_1 1385658.U5KPZ6_9VIRU 2.06e-35 138.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_55182_1 1429767.W6ARM9_9CAUD 8.39e-40 146.0 4QGGR@10239|Viruses,4QZHR@35237|dsDNA viruses no RNA stage,4QUGZ@28883|Caudovirales,4QNY3@10744|Podoviridae 10744|Podoviridae S viral capsid - - - - - - - - - - - - - k59_591982_1 1408813.AYMG01000038_gene270 3.15e-90 293.0 COG0286@1|root,COG0732@1|root,COG0286@2|Bacteria,COG0732@2|Bacteria 2|Bacteria V type I restriction modification DNA specificity domain - - 2.1.1.72 ko:K03427,ko:K07317 - - - - ko00000,ko01000,ko02048 - - - Eco57I,HSDR_N_2,Methylase_S,N6_Mtase,TaqI_C k59_407357_3 1283283.ATXA01000006_gene1855 1.61e-22 97.8 COG0464@1|root,COG0464@2|Bacteria 2|Bacteria O ATPase activity - - - - - - - - - - - - AAA k59_283849_1 1160137.KB907309_gene5493 1.1e-32 125.0 COG0270@1|root,COG0270@2|Bacteria,2GNB2@201174|Actinobacteria,4G2GK@85025|Nocardiaceae 201174|Actinobacteria L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_219823_4 160799.PBOR_26750 4.41e-18 94.0 2EYIP@1|root,33RSF@2|Bacteria,1VSNU@1239|Firmicutes,4HUJ1@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k59_470918_3 631362.Thi970DRAFT_03076 2.77e-27 100.0 2EH2T@1|root,33AUS@2|Bacteria,1NIC1@1224|Proteobacteria,1SJET@1236|Gammaproteobacteria,1X18R@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k59_226643_3 330396.A8ATF8_9CAUD 9.36e-16 74.3 4QAKE@10239|Viruses,4QUP7@35237|dsDNA viruses no RNA stage,4QPCE@28883|Caudovirales,4QKTX@10699|Siphoviridae 10699|Siphoviridae S HNH endonuclease - - - - - - - - - - - - - k59_473310_2 1173762.S4TP25_9CAUD 4.78e-138 421.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_473310_4 1283071.R9R5B2_9CAUD 1.29e-68 236.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_473310_6 572544.Ilyop_0371 5.7e-41 141.0 COG0756@1|root,COG0756@2|Bacteria,37A2G@32066|Fusobacteria 32066|Fusobacteria F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA dut GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase k59_288264_1 1408823.AXUS01000024_gene2703 2.47e-08 57.4 COG4570@1|root,COG4570@2|Bacteria 2|Bacteria L crossover junction endodeoxyribonuclease activity rusA - 3.1.22.4 ko:K01160 - - - - ko00000,ko01000,ko03400 - - - RusA k59_288264_2 1041147.AUFB01000014_gene357 3.56e-09 68.9 COG5519@1|root,COG5519@2|Bacteria,1QU3K@1224|Proteobacteria,2TVXZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Bifunctional DNA primase/polymerase, N-terminal - - - - - - - - - - - - DUF3987,Prim-Pol k59_452669_2 1133022.I6NPA3_9CAUD 6.78e-19 91.7 4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_595939_4 1120968.AUBX01000010_gene922 1.26e-11 64.3 2AR54@1|root,31GER@2|Bacteria,4NSCR@976|Bacteroidetes,47VAR@768503|Cytophagia 976|Bacteroidetes S 23S rRNA-intervening sequence protein - - - - - - - - - - - - 23S_rRNA_IVP k59_616764_2 1051675.G0YQF5_9CAUD 1.47e-39 152.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_370340_8 1206557.I7KQW5_9CAUD 7.61e-18 83.6 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales,4QKM7@10699|Siphoviridae 10699|Siphoviridae S HNH endonuclease - - - - - - - - - - - - - k59_124236_1 398720.MED217_15260 8.32e-11 71.6 COG5295@1|root,COG5295@2|Bacteria,4NJTK@976|Bacteroidetes,1HZNB@117743|Flavobacteriia 976|Bacteroidetes UW surface antigen - - - - - - - - - - - - Peptidase_S74 k59_103584_2 1692253.A0A0K1RLM4_9CIRC 2.28e-31 125.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_514407_1 357804.Ping_1595 1.36e-41 152.0 2CWXD@1|root,32T0J@2|Bacteria,1N3Z7@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_205805_1 443598.AUFA01000067_gene1958 0.000234 47.8 2DCY5@1|root,2ZFSD@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_205805_2 882.DVU_2154 8.4e-07 50.1 COG0791@1|root,COG0791@2|Bacteria,1N732@1224|Proteobacteria,42Y2T@68525|delta/epsilon subdivisions,2WSQU@28221|Deltaproteobacteria,2MFUQ@213115|Desulfovibrionales 28221|Deltaproteobacteria M NlpC/P60 family - - - - - - - - - - - - NLPC_P60 k59_124244_3 100226.SCO7392 2.96e-39 136.0 arCOG05626@1|root,32V4D@2|Bacteria,2I38M@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_370553_1 658401.C7F4B8_9CAUD 0.000566 50.1 4QH5W@10239|Viruses,4QYFG@35237|dsDNA viruses no RNA stage,4QQD8@28883|Caudovirales,4QN2T@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_598467_1 936455.KI421499_gene5909 1.89e-17 90.5 COG3409@1|root,COG3772@1|root,COG3409@2|Bacteria,COG3772@2|Bacteria,1QW72@1224|Proteobacteria,2UBY3@28211|Alphaproteobacteria,3K0F5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Peptidoglycan-binding domain 1 protein - - - - - - - - - - - - - k59_455996_4 871968.DESME_08930 2.02e-58 214.0 2E2CM@1|root,32XHK@2|Bacteria,1VCFP@1239|Firmicutes,24Q3M@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_598719_3 1234888.K0A2J2_9VIRU 3e-131 395.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_517775_2 349161.Dred_1189 1.28e-31 121.0 28J2E@1|root,2Z8YX@2|Bacteria,1TRF9@1239|Firmicutes,249U3@186801|Clostridia 186801|Clostridia S Protein of unknown function (DUF2815) - - - - - - - - - - - - DUF2815 k59_517775_4 1555208.A0A097EW24_9CAUD 3.27e-28 118.0 4QAKM@10239|Viruses,4QPEF@28883|Caudovirales,4QKNE@10699|Siphoviridae 10699|Siphoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_517775_5 662755.CRES_0898 2.09e-38 157.0 COG0749@1|root,COG0749@2|Bacteria,2IG0A@201174|Actinobacteria,22MKV@1653|Corynebacteriaceae 201174|Actinobacteria L DNA polymerase I - 3'-5' exonuclease and polymerase domains - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_517775_7 696281.Desru_1084 3.4e-29 123.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia 186801|Clostridia L snf2 family - - - - - - - - - - - - SNF2_N k59_127312_1 469618.FVAG_02954 9.36e-11 68.9 COG3209@1|root,COG3209@2|Bacteria,37B7F@32066|Fusobacteria 32066|Fusobacteria M Chaperone of endosialidase - - - - - - - - - - - - Peptidase_S74 k59_435745_1 1423758.BN55_01455 6.05e-69 230.0 COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,1TPHP@1239|Firmicutes,4HC9M@91061|Bacilli,3F5AA@33958|Lactobacillaceae 91061|Bacilli KL DNA methylase - - - - - - - - - - - - N6_N4_Mtase,ParBc k59_150367_1 76114.ebA5488 5.21e-11 67.4 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2VNHP@28216|Betaproteobacteria 28216|Betaproteobacteria S Terminase - - - - - - - - - - - - Terminase_1 k59_521580_3 1396141.BATP01000029_gene2258 1.96e-19 91.3 2E0FE@1|root,32W1M@2|Bacteria,46TEN@74201|Verrucomicrobia,2IVPU@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Domain of unknown function (DUF932) - - - - - - - - - - - - DUF932 k59_27272_1 395961.Cyan7425_3706 9.83e-45 157.0 COG0338@1|root,COG0338@2|Bacteria,1G2H8@1117|Cyanobacteria,3KHAX@43988|Cyanothece 1117|Cyanobacteria H D12 class N6 adenine-specific DNA methyltransferase dmnB - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 k59_273477_1 867845.KI911784_gene557 2.94e-31 119.0 COG0675@1|root,COG0675@2|Bacteria,2G823@200795|Chloroflexi,3779K@32061|Chloroflexia 32061|Chloroflexia L Putative transposase DNA-binding domain - - - - - - - - - - - - HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon k59_521630_1 582345.D6RRU0_BPKPP 6.47e-09 62.0 4QAUT@10239|Viruses,4QVIM@35237|dsDNA viruses no RNA stage,4QQ7X@28883|Caudovirales,4QIGV@10662|Myoviridae 10662|Myoviridae S DNA ligase (ATP) activity - - - - - - - - - - - - - k59_560427_2 101510.RHA1_ro01428 1.14e-53 173.0 COG1403@1|root,COG1403@2|Bacteria,2GYWG@201174|Actinobacteria,4G243@85025|Nocardiaceae 201174|Actinobacteria L HNH nucleases - - - - - - - - - - - - HNH,HNH_3 k59_560427_4 546805.B5LJE6_9CAUD 7.55e-13 66.2 4QFUH@10239|Viruses,4QZ2M@35237|dsDNA viruses no RNA stage,4QSQV@28883|Caudovirales,4QI2M@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_336886_2 257310.BB2209 1.87e-09 60.5 COG0305@1|root,COG0305@2|Bacteria,1PP51@1224|Proteobacteria,2VQ9Z@28216|Betaproteobacteria,3T82N@506|Alcaligenaceae 28216|Betaproteobacteria L DnaB-like helicase C terminal domain - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - AAA_25,DnaB_C k59_313816_1 1051675.G0YQH7_9CAUD 1.57e-09 64.7 4QGGR@10239|Viruses,4QZHR@35237|dsDNA viruses no RNA stage,4QUGZ@28883|Caudovirales,4QNY3@10744|Podoviridae 10744|Podoviridae S viral capsid - - - - - - - - - - - - - k59_481657_1 1385658.U5KNR1_9VIRU 2.4e-26 108.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_399942_4 490103.B0FII1_BPE32 1.21e-14 82.4 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QNI0@10744|Podoviridae 10744|Podoviridae S viral capsid - GO:0003674,GO:0005488,GO:0005515,GO:0042802 - - - - - - - - - - - k59_526788_1 231434.JQJH01000012_gene2822 9.91e-14 73.9 COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,2UFII@28211|Alphaproteobacteria 28211|Alphaproteobacteria S VWA-like domain (DUF2201) - - - - - - - - - - - - DUF2201,DUF2201_N k59_526788_2 748224.HMPREF9436_02205 1.05e-11 73.9 COG0714@1|root,COG0714@2|Bacteria,1U8NZ@1239|Firmicutes,248X1@186801|Clostridia,3WHAV@541000|Ruminococcaceae 186801|Clostridia S AAA domain (dynein-related subfamily) - - - - - - - - - - - - AAA,AAA_5 k59_421015_1 39416.CAZ84400 2.99e-05 48.9 COG1678@1|root,KOG1567@2759|Eukaryota,38B80@33154|Opisthokonta,3NW0V@4751|Fungi,3QKBC@4890|Ascomycota 4751|Fungi F reductase small RNR2 GO:0003674,GO:0003824,GO:0004748,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006240,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009147,GO:0009148,GO:0009165,GO:0009185,GO:0009186,GO:0009189,GO:0009193,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009215,GO:0009216,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0032991,GO:0034641,GO:0034654,GO:0042278,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046062,GO:0046131,GO:0046385,GO:0046483,GO:0046704,GO:0051063,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0072521,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1902494,GO:1990204 1.17.4.1 ko:K10808 ko00230,ko00240,ko00480,ko00983,ko01100,ko04115,map00230,map00240,map00480,map00983,map01100,map04115 M00053 R02017,R02019,R02024,R08363,R08364,R11893 RC00613,RC01003 ko00000,ko00001,ko00002,ko01000,ko03400 - - iMM904.YJL026W,iND750.YJL026W Ribonuc_red_sm k59_176506_1 1449343.JQLQ01000002_gene1549 2.95e-24 102.0 COG3723@1|root,COG3723@2|Bacteria,1V3B6@1239|Firmicutes,4HG19@91061|Bacilli,27HB5@186828|Carnobacteriaceae 91061|Bacilli L RecT family bet - - - - - - - - - - - RecT k59_257964_2 1121930.AQXG01000012_gene3236 8.63e-12 70.9 COG2911@1|root,COG5295@1|root,COG2911@2|Bacteria,COG5295@2|Bacteria,4NMJW@976|Bacteroidetes 976|Bacteroidetes UW Hep Hag repeat protein - - - - - - - - - - - - DUF1566,Peptidase_S74 k59_547815_1 294631.Q5ZGD7_9CAUD 1.98e-15 82.0 4QGUS@10239|Viruses,4QX38@35237|dsDNA viruses no RNA stage,4QRVV@28883|Caudovirales,4QN8J@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_605744_2 1609634.A0A0C5ANA6_9VIRU 1.53e-10 67.4 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_31377_1 66875.JODY01000017_gene569 2.49e-30 114.0 2EGA5@1|root,33A1Y@2|Bacteria,2GSDD@201174|Actinobacteria 201174|Actinobacteria S HNH endonuclease - - - - - - - - - - - - HNH_3 k59_277406_2 1000569.HMPREF1040_0207 1.02e-11 68.9 28J2E@1|root,2Z8YX@2|Bacteria,1TRF9@1239|Firmicutes,4H7E2@909932|Negativicutes 909932|Negativicutes S Protein of unknown function (DUF2815) - - - - - - - - - - - - DUF2815 k59_213897_1 1540098.A0A0A0RQI2_9CAUD 5.22e-29 124.0 4QB5I@10239|Viruses,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_213897_5 1196323.ALKF01000200_gene2705 2.58e-77 242.0 COG0207@1|root,COG0207@2|Bacteria,1TSIR@1239|Firmicutes,4H9QS@91061|Bacilli,26T1B@186822|Paenibacillaceae 91061|Bacilli F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA - 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt k59_213897_6 767434.Fraau_1253 1.41e-23 96.7 COG2131@1|root,COG2131@2|Bacteria,1NC75@1224|Proteobacteria,1T01U@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Deoxycytidylate deaminase - - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 k59_213897_7 1538804.A0A088F6T3_9CAUD 2.92e-86 299.0 4QAKM@10239|Viruses,4QPEF@28883|Caudovirales,4QKNE@10699|Siphoviridae 10699|Siphoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_527537_2 1304880.JAGB01000003_gene1191 4.21e-28 115.0 COG0201@1|root,COG0201@2|Bacteria,1TPHB@1239|Firmicutes,248T9@186801|Clostridia 186801|Clostridia U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY - - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY k59_564612_1 691965.D4P7E6_9CAUD 5.37e-95 312.0 4QAK6@10239|Viruses,4R01K@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_50185_2 1234888.K0A2J2_9VIRU 2.05e-39 145.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_12083_1 1146883.BLASA_2790 8.89e-18 84.7 COG1266@1|root,COG1266@2|Bacteria,2GKRA@201174|Actinobacteria,4EVQR@85013|Frankiales 201174|Actinobacteria S Abortive infection protein - - - ko:K07052 - - - - ko00000 - - - Abi k59_12083_2 547163.BN979_02388 2.9e-15 79.0 COG0596@1|root,COG0596@2|Bacteria,2HF12@201174|Actinobacteria,238C8@1762|Mycobacteriaceae 201174|Actinobacteria S Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 k59_258019_1 1122180.Lokhon_03139 3.69e-11 68.6 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2VBK9@28211|Alphaproteobacteria,2PA3A@245186|Loktanella 28211|Alphaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_566995_7 909663.KI867149_gene3255 1.64e-28 112.0 COG1475@1|root,COG1475@2|Bacteria 2|Bacteria K chromosome segregation - - - - - - - - - - - - N6_N4_Mtase,ParBc k59_566995_10 1329250.WOSG25_260090 3.96e-41 154.0 COG3757@1|root,COG5632@1|root,COG3757@2|Bacteria,COG5632@2|Bacteria,1VABA@1239|Firmicutes,4HKUV@91061|Bacilli,4AYNF@81850|Leuconostocaceae 91061|Bacilli M Lyzozyme M1 - - - ko:K07273 - - - - ko00000 - - - Glyco_hydro_25,ZoocinA_TRD k59_566995_15 1215915.BN193_09055 7.57e-72 253.0 COG5185@1|root,COG5412@1|root,COG5185@2|Bacteria,COG5412@2|Bacteria,1TPR1@1239|Firmicutes,4HC94@91061|Bacilli,1YCBA@1357|Lactococcus 91061|Bacilli D phage tail tape measure protein - - - - - - - - - - - - PhageMin_Tail k59_566995_19 883077.HMPREF9241_01703 3.67e-51 169.0 COG5492@1|root,COG5492@2|Bacteria,2IK71@201174|Actinobacteria 201174|Actinobacteria N domain, Protein - - - - - - - - - - - - - k59_566995_29 706433.HMPREF9430_01265 3.74e-37 141.0 28IBR@1|root,2Z8E5@2|Bacteria,1TS1H@1239|Firmicutes 1239|Firmicutes S Phage capsid family - - - - - - - - - - - - Phage_capsid k59_180019_1 639283.Snov_1953 5.41e-16 89.0 COG5281@1|root,COG5281@2|Bacteria,1MX2R@1224|Proteobacteria,2TW9T@28211|Alphaproteobacteria,3F0FI@335928|Xanthobacteraceae 28211|Alphaproteobacteria S tape measure protein - - - - - - - - - - - - - k59_383549_1 1788439.A0A190WHD0_9CIRC 1.03e-07 54.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_531639_1 313606.M23134_08279 0.000649 50.4 COG1361@1|root,COG1409@1|root,COG2931@1|root,COG3420@1|root,COG4886@1|root,COG1361@2|Bacteria,COG1409@2|Bacteria,COG2931@2|Bacteria,COG3420@2|Bacteria,COG4886@2|Bacteria,4PMET@976|Bacteroidetes 976|Bacteroidetes Q Concanavalin A-like lectin/glucanases superfamily - - - - - - - - - - - - Laminin_G_3 k59_320797_1 485913.Krac_6819 2.27e-14 73.2 293RF@1|root,2ZR72@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_588278_3 1307436.PBF_14979 7.51e-12 61.6 COG0695@1|root,COG0695@2|Bacteria,1VIGD@1239|Firmicutes,4HNUE@91061|Bacilli,1ZHUC@1386|Bacillus 91061|Bacilli O Glutaredoxin - - - - - - - - - - - - Glutaredoxin k59_552671_2 1385658.U5KNR1_9VIRU 1.75e-59 201.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_101043_1 1618240.A0A0C5IMJ1_9CIRC 1.08e-71 227.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_532442_1 857293.CAAU_0906 1.6e-15 82.4 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,2487V@186801|Clostridia,36EDD@31979|Clostridiaceae 186801|Clostridia L DNA polymerase - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_613402_1 1493511.A0A0E3HRS2_9CAUD 2.12e-16 79.0 4QDAY@10239|Viruses,4QTPU@28883|Caudovirales,4QKG9@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_327361_1 172088.AUGA01000071_gene7567 2.76e-51 194.0 COG3740@1|root,COG3740@2|Bacteria,1QVIJ@1224|Proteobacteria,2TVIM@28211|Alphaproteobacteria,3K0XM@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Caudovirus prohead serine protease - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_58036_2 1504981.KO116_4059 1.7e-28 114.0 28HEE@1|root,2Z7QU@2|Bacteria,1MXU6@1224|Proteobacteria,1RZSJ@1236|Gammaproteobacteria,1XNV1@135619|Oceanospirillales 135619|Oceanospirillales S Domain of unknown function (DUF932) - - - - - - - - - - - - DUF932 k59_409515_1 227882.SAP1_18 1.19e-15 81.6 COG1061@1|root,COG1061@2|Bacteria 2|Bacteria L Type III restriction enzyme res subunit - - - - - - - - - - - - HA,Helicase_C,Mrr_cat_2,ResIII k59_244512_1 1410631.JHWZ01000012_gene2061 1.43e-08 58.9 COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,249EA@186801|Clostridia,27JTZ@186928|unclassified Lachnospiraceae 186801|Clostridia S Putative single-stranded nucleic acids-binding domain jag - - ko:K06346 - - - - ko00000 - - - Jag_N,KH_4,R3H k59_594192_1 1423754.BALY01000006_gene1325 7.55e-05 48.5 COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,4HAYW@91061|Bacilli,3F3X9@33958|Lactobacillaceae 91061|Bacilli F Essential for recycling GMP and indirectly, cGMP gmk GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15680 Guanylate_kin k59_81377_2 1206558.I7LHB5_9CAUD 4.06e-05 48.5 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QI82@10662|Myoviridae 10662|Myoviridae S virus tail, fiber - GO:0005575,GO:0019012 - - - - - - - - - - - k59_594199_1 1041138.KB890232_gene6066 2.44e-129 397.0 COG2189@1|root,COG2189@2|Bacteria,1MX9M@1224|Proteobacteria,2U066@28211|Alphaproteobacteria,4BMUP@82115|Rhizobiaceae 28211|Alphaproteobacteria L dna methylase - - 2.1.1.72 ko:K07316 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_573700_1 373407.Q1A0N7_9CAUD 1.93e-18 89.4 4QBP3@10239|Viruses,4QVAZ@35237|dsDNA viruses no RNA stage,4QPEQ@28883|Caudovirales,4QM06@10699|Siphoviridae 10699|Siphoviridae S PDDEXK-like domain of unknown function (DUF3799) - - - - - - - - - - - - - k59_327432_1 1122201.AUAZ01000017_gene2960 1.46e-55 189.0 COG5362@1|root,COG5362@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Terminase_6C k59_573750_1 1051675.G0YQG3_9CAUD 4.34e-29 114.0 4QEG2@10239|Viruses,4QVSD@35237|dsDNA viruses no RNA stage,4QRJ9@28883|Caudovirales,4QP0R@10744|Podoviridae 10744|Podoviridae S exonuclease activity - - - - - - - - - - - - - k59_573750_2 1051675.G0YQF5_9CAUD 8.75e-29 116.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_162396_1 691965.D4P7D6_9CAUD 5.18e-61 209.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_244542_9 1208587.S6CQN3_9CAUD 6.87e-15 76.3 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales,4QKM7@10699|Siphoviridae 10699|Siphoviridae S HNH endonuclease - - - - - - - - - - - - - k59_83980_1 1219077.VAZ01S_090_00200 1.46e-122 367.0 COG3969@1|root,COG3969@2|Bacteria,1NBDM@1224|Proteobacteria,1RYRP@1236|Gammaproteobacteria,1XT86@135623|Vibrionales 135623|Vibrionales S Domain of unknown function (DUF3440) - - - - - - - - - - - - DUF3440,PAPS_reduct k59_165711_1 1429767.W6B150_9CAUD 7.05e-62 214.0 4QF3C@10239|Viruses,4QWIA@35237|dsDNA viruses no RNA stage,4QU4U@28883|Caudovirales,4QNNQ@10744|Podoviridae 10744|Podoviridae S host cell wall - - - - - - - - - - - - - k59_227062_2 37919.EP51_10315 5.16e-125 365.0 COG1131@1|root,COG1131@2|Bacteria,2GKEH@201174|Actinobacteria,4FUJH@85025|Nocardiaceae 201174|Actinobacteria V ABC transporter ATP-binding - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 k59_473859_1 1262513.K7YIR2_9CAUD 7.36e-05 51.6 4QAKE@10239|Viruses,4QUP7@35237|dsDNA viruses no RNA stage,4QPCE@28883|Caudovirales,4QI56@10662|Myoviridae 10662|Myoviridae S nucleic acid binding - - - - - - - - - - - - - k59_432205_2 1476390.A0A060RFG9_9CAUD 6.53e-24 101.0 4QBA5@10239|Viruses,4QXFW@35237|dsDNA viruses no RNA stage,4QPTU@28883|Caudovirales,4QN4A@10699|Siphoviridae 10699|Siphoviridae S AAA domain - - - - - - - - - - - - - k59_1850_1 1234679.BN424_1486 5.86e-29 115.0 COG3772@1|root,COG3772@2|Bacteria,1VQ7P@1239|Firmicutes,4ITH9@91061|Bacilli 91061|Bacilli G Phage lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_330227_2 502025.Hoch_1300 8.26e-05 52.4 COG0535@1|root,COG0535@2|Bacteria,1PVRY@1224|Proteobacteria,4380G@68525|delta/epsilon subdivisions,2X9U8@28221|Deltaproteobacteria,2YZH0@29|Myxococcales 28221|Deltaproteobacteria S Elongator protein 3, MiaB family, Radical SAM - - - - - - - - - - - - Radical_SAM k59_330227_7 349161.Dred_1404 1.37e-107 328.0 2EYIP@1|root,33RSF@2|Bacteria,1VSNU@1239|Firmicutes,24YEW@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_432214_1 388051.AUFE01000035_gene4020 7.02e-11 63.2 COG4653@1|root,COG4653@2|Bacteria 2|Bacteria G Phage capsid family - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_411870_2 1379709.S5TMV0_9CIRC 2.61e-72 226.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_555434_3 985762.SAGN_06040 6.19e-17 77.8 COG1403@1|root,COG1403@2|Bacteria,1VA8J@1239|Firmicutes,4HNCA@91061|Bacilli,4GZVD@90964|Staphylococcaceae 91061|Bacilli L COG1403 Restriction endonuclease - - - ko:K07451 - - - - ko00000,ko01000,ko02048 - - - HNH k59_620525_2 145579.CAPSD_BPPHM 5.26e-79 264.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_88108_1 1492922.GY26_01800 8.71e-08 63.5 COG1196@1|root,COG4733@1|root,COG1196@2|Bacteria,COG4733@2|Bacteria 2|Bacteria S cellulase activity - - - ko:K02316,ko:K06882 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - AAA_15,FIVAR k59_106523_2 1283340.Q6WI94_BPKVM 1.34e-06 56.2 4QAUT@10239|Viruses,4QVIM@35237|dsDNA viruses no RNA stage,4QQ7X@28883|Caudovirales,4QIGV@10662|Myoviridae 10662|Myoviridae S DNA ligase (ATP) activity - - - - - - - - - - - - - k59_519312_1 1122236.KB905146_gene1926 3.24e-19 92.0 COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,2VI5Q@28216|Betaproteobacteria,2KM9S@206350|Nitrosomonadales 206350|Nitrosomonadales M Peptidoglycan polymerase that is essential for cell division ftsW - - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE k59_25453_2 445686.E3SKU6_9CAUD 6.82e-12 77.8 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QI82@10662|Myoviridae 10662|Myoviridae S virus tail, fiber - - - - - - - - - - - - - k59_334629_1 1561065.A0A0B5A7I7_9CAUD 1.9e-76 263.0 4QBSJ@10239|Viruses,4QPFJ@28883|Caudovirales,4QKUK@10699|Siphoviridae 10699|Siphoviridae S DNA primase activity - - - - - - - - - - - - - k59_415510_1 107636.JQNK01000002_gene117 0.00039 45.8 COG0582@1|root,COG0582@2|Bacteria,1N2H9@1224|Proteobacteria,2TS7K@28211|Alphaproteobacteria,36YAE@31993|Methylocystaceae 28211|Alphaproteobacteria L Phage integrase family - - - - - - - - - - - - Arm-DNA-bind_3,Phage_int_SAM_3,Phage_integrase k59_579338_1 1214065.BAGV01000099_gene2076 2e-110 331.0 COG3969@1|root,COG3969@2|Bacteria,1NBDM@1224|Proteobacteria,1RYRP@1236|Gammaproteobacteria 1236|Gammaproteobacteria S phosphoadenosine phosphosulfate ybdN - - - - - - - - - - - DUF3440,PAPS_reduct k59_394569_2 1328029.S0A1Z2_9CAUD 6.58e-116 358.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_66758_1 1250232.JQNJ01000001_gene2061 3.37e-09 65.5 COG1361@1|root,COG2982@1|root,COG3210@1|root,COG4932@1|root,COG1361@2|Bacteria,COG2982@2|Bacteria,COG3210@2|Bacteria,COG4932@2|Bacteria,4NG16@976|Bacteroidetes,1HY10@117743|Flavobacteriia 976|Bacteroidetes M C-terminal domain of CHU protein family - - - - - - - - - - - - CHU_C,Calx-beta,DUF11,SdrD_B k59_48337_1 1235661.K0IGL1_9CAUD 1.84e-26 112.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QNI0@10744|Podoviridae 10744|Podoviridae S viral capsid - GO:0003674,GO:0005488,GO:0005515,GO:0042802 - - - - - - - - - - - k59_173608_1 649639.Bcell_2721 2.56e-89 294.0 COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,1UHQM@1239|Firmicutes,4HGW7@91061|Bacilli,1ZBWW@1386|Bacillus 91061|Bacilli D phage tail tape measure protein - - - - - - - - - - - - Peptidase_M23,PhageMin_Tail,SLT k59_28715_2 537874.B3GVX7_9CAUD 4.73e-12 68.6 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales,4QKM7@10699|Siphoviridae 10699|Siphoviridae S HNH endonuclease - - - - - - - - - - - - - k59_274772_1 105154.Q9MBU6_9VIRU 4.05e-111 340.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_582592_1 1234888.K0A2J2_9VIRU 8.59e-55 188.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_355818_2 358220.C380_12195 2.43e-72 230.0 COG0582@1|root,COG0582@2|Bacteria,1NWGS@1224|Proteobacteria,2VKWM@28216|Betaproteobacteria 28216|Betaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_integrase k59_397891_1 1385658.U5KPZ6_9VIRU 7.3e-29 122.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_339581_2 942016.E9NIJ0_9CAUD 1.76e-33 128.0 4QF0B@10239|Viruses,4QX8P@35237|dsDNA viruses no RNA stage,4QSJT@28883|Caudovirales,4QNNK@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_460906_2 1380894.S5TR92_9CIRC 4.72e-53 181.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_48704_1 1033733.CAEK01000007_gene1593 1.19e-31 132.0 COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,22FY9@1570339|Peptoniphilaceae 186801|Clostridia L DNA-directed DNA polymerase dnaE - 2.7.7.7 ko:K02337,ko:K14162 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k59_603489_1 1609634.A0A0C5ANA6_9VIRU 2.97e-15 77.8 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_484095_1 1432056.X781_11190 2.85e-29 120.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,1RP8Z@1236|Gammaproteobacteria,1Y9US@135625|Pasteurellales 135625|Pasteurellales S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_460919_1 1385658.U5KPZ6_9VIRU 2.08e-61 206.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_339610_1 1165094.RINTHH_3920 5.88e-30 119.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_339610_2 105154.Q9MBT9_9VIRU 2.19e-15 71.6 4QCC5@10239|Viruses,4QUKW@29258|ssDNA viruses,4QP4C@10841|Microviridae 10841|Microviridae S viral process - - - - - - - - - - - - - k59_339610_3 1385658.U5KPZ6_9VIRU 3.83e-156 459.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_51060_1 1449351.RISW2_21770 7.1e-22 102.0 COG1196@1|root,COG3941@1|root,COG1196@2|Bacteria,COG3941@2|Bacteria 2|Bacteria O tape measure - - - - - - - - - - - - PhageMin_Tail,TMP_2,Tape_meas_lam_C k59_98109_2 1443665.JACA01000064_gene4790 4.1e-37 132.0 2DYRW@1|root,34AUU@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_565774_2 1618248.A0A0C5IB82_9CIRC 4.1e-35 138.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_465457_1 406818.XBJ1_2043 9.43e-123 372.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,1SMCU@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_74432_2 393480.FNP_1672 4.35e-14 71.6 COG5377@1|root,COG5377@2|Bacteria 2|Bacteria L YqaJ viral recombinase family - - - - - - - - - - - - YqaJ k59_344813_1 1268240.ATFI01000008_gene2581 4.58e-06 49.3 COG1783@1|root,COG1783@2|Bacteria,4PMA2@976|Bacteroidetes,2G2CX@200643|Bacteroidia,4AVWS@815|Bacteroidaceae 976|Bacteroidetes S Terminase RNAseH like domain - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C k59_550453_1 1234888.K0A2J2_9VIRU 3.4e-57 193.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_201590_1 1484157.PSNIH2_13485 1.54e-16 77.4 28J67@1|root,2Z91Y@2|Bacteria,1R7RG@1224|Proteobacteria,1RZB8@1236|Gammaproteobacteria,3W0AP@53335|Pantoea 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_55522_1 1123508.JH636447_gene7991 1.72e-66 217.0 COG2401@1|root,COG2401@2|Bacteria,2IYZ0@203682|Planctomycetes 203682|Planctomycetes K acetyltransferase - - - - - - - - - - - - - k59_387788_1 762982.HMPREF9442_00544 9.57e-27 101.0 2C7AV@1|root,32S15@2|Bacteria,4NUJ2@976|Bacteroidetes,2FXZ4@200643|Bacteroidia 976|Bacteroidetes S zinc-finger-containing domain - - - - - - - - - - - - DUF3268 k59_304709_2 189753.AXAS01000012_gene4367 1.16e-20 88.6 2DMHT@1|root,32RN3@2|Bacteria,1N0KK@1224|Proteobacteria,2UCFK@28211|Alphaproteobacteria,3JZ5E@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - MA20_36130 - - - - - - - - - - - PEGA k59_304709_3 932213.SPM24T3_17060 8.23e-09 59.3 COG1396@1|root,COG2932@1|root,COG1396@2|Bacteria,COG2932@2|Bacteria,1R80S@1224|Proteobacteria,1S1UR@1236|Gammaproteobacteria,403ZC@613|Serratia 1236|Gammaproteobacteria K Peptidase S24-like - - - - - - - - - - - - HTH_3,HTH_31,Peptidase_S24 k59_219341_1 1788454.A0A190WHE4_9CIRC 2.59e-12 71.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_509362_1 714083.JH370377_gene1444 4.29e-24 107.0 COG1215@1|root,COG1215@2|Bacteria,2IK1V@201174|Actinobacteria 201174|Actinobacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - - k59_591519_1 716928.AJQT01000109_gene1178 1.46e-28 115.0 COG0553@1|root,COG0553@2|Bacteria,1R7CK@1224|Proteobacteria,2U228@28211|Alphaproteobacteria,4BN0G@82115|Rhizobiaceae 28211|Alphaproteobacteria KL DNA methylase N-4 - - - - - - - - - - - - Helicase_C,N6_N4_Mtase k59_142184_1 1463864.JOGO01000036_gene2520 7.56e-07 56.6 COG0419@1|root,COG1842@1|root,COG3953@1|root,COG5412@1|root,COG0419@2|Bacteria,COG1842@2|Bacteria,COG3953@2|Bacteria,COG5412@2|Bacteria,2GNNQ@201174|Actinobacteria 201174|Actinobacteria KT Phage tail tape measure protein TP901 - - - - - - - - - - - - NLPC_P60,SLT k59_639221_2 563192.HMPREF0179_02963 1.52e-11 67.0 COG1196@1|root,COG3941@1|root,COG1196@2|Bacteria,COG3941@2|Bacteria 2|Bacteria O tape measure - - - ko:K03529 - - - - ko00000,ko03036 - - - PhageMin_Tail,Tape_meas_lam_C k59_371745_1 1120985.AUMI01000001_gene2164 3.74e-10 66.2 COG5281@1|root,COG5281@2|Bacteria,1TPWF@1239|Firmicutes,4H3NF@909932|Negativicutes 909932|Negativicutes S tape measure - - - - - - - - - - - - - k59_597345_1 1123487.KB892865_gene1394 6.88e-59 201.0 COG0749@1|root,COG0749@2|Bacteria,1MWX7@1224|Proteobacteria,2VMZW@28216|Betaproteobacteria 28216|Betaproteobacteria L DNA polymerase family A - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_289928_1 1094466.KQS_02590 2.74e-07 61.6 COG4733@1|root,COG4733@2|Bacteria,4PPGG@976|Bacteroidetes,1IKM3@117743|Flavobacteriia,2P0RW@237|Flavobacterium 976|Bacteroidetes S Concanavalin A-like lectin/glucanases superfamily - - - - - - - - - - - - Laminin_G_3 k59_433445_1 1556290.A0A0A0RM05_9CAUD 2.94e-143 429.0 4QAYV@10239|Viruses,4QPU3@28883|Caudovirales,4QKKX@10699|Siphoviridae 10699|Siphoviridae S Phage portal protein - - - - - - - - - - - - - k59_187513_1 1327977.R9ZXS2_9CAUD 4.06e-61 199.0 4QARC@10239|Viruses,4QV4E@35237|dsDNA viruses no RNA stage,4QPDS@28883|Caudovirales,4QP0H@10744|Podoviridae 10744|Podoviridae S nucleic acid binding - - - - - - - - - - - - - k59_475222_2 1475143.W8SNN0_9CIRC 6.06e-41 150.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_556426_1 1306990.BARG01000020_gene1898 1.36e-06 49.3 COG1814@1|root,COG1814@2|Bacteria,2GIZ3@201174|Actinobacteria 201174|Actinobacteria S membrane - - - - - - - - - - - - VIT1 k59_556426_2 1828.JOKB01000008_gene339 5.51e-97 295.0 COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4FUZ1@85025|Nocardiaceae 201174|Actinobacteria V ABC transporter - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 k59_207141_1 1331060.RLDS_16020 2.13e-37 141.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2TSDW@28211|Alphaproteobacteria,2K42P@204457|Sphingomonadales 204457|Sphingomonadales S Terminase - - - - - - - - - - - - Terminase_1 k59_43664_2 428125.CLOLEP_01413 1.55e-35 124.0 2E2Y0@1|root,32XYV@2|Bacteria,1VD9S@1239|Firmicutes,24PK0@186801|Clostridia,3WPDR@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_43664_3 691965.D4P7D8_9CAUD 2.92e-32 115.0 4QBBW@10239|Viruses,4QXCP@35237|dsDNA viruses no RNA stage,4QQ3N@28883|Caudovirales,4QN1X@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_43664_4 742733.HMPREF9469_05026 1.34e-45 154.0 28NM4@1|root,2ZBMQ@2|Bacteria,1V1QD@1239|Firmicutes,24G1B@186801|Clostridia,221N8@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_577405_1 326424.FRAAL2754 6.07e-13 71.6 28HEE@1|root,2Z7QU@2|Bacteria,2I1I5@201174|Actinobacteria 201174|Actinobacteria S Domain of unknown function (DUF932) - - - - - - - - - - - - DUF932 k59_372141_2 1229172.JQFA01000002_gene4632 6.63e-25 102.0 COG3772@1|root,COG3772@2|Bacteria,1G7YF@1117|Cyanobacteria,1HASB@1150|Oscillatoriales 1117|Cyanobacteria M Phage lysozyme - - - - - - - - - - - - PG_binding_1,Phage_lysozyme k59_478182_1 1357279.N018_05425 2.01e-12 77.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,1SMCU@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_148369_2 395961.Cyan7425_3706 1.92e-51 175.0 COG0338@1|root,COG0338@2|Bacteria,1G2H8@1117|Cyanobacteria,3KHAX@43988|Cyanothece 1117|Cyanobacteria H D12 class N6 adenine-specific DNA methyltransferase dmnB - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 k59_373777_1 1227739.Hsw_3348 3.14e-16 82.8 COG1783@1|root,COG1783@2|Bacteria,4NSZ4@976|Bacteroidetes,47P61@768503|Cytophagia 976|Bacteroidetes S phage Terminase large subunit - - - - - - - - - - - - - k59_436675_2 1423144.Gal_02255 2.14e-10 63.5 2EK50@1|root,33DVF@2|Bacteria,1NK6R@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_209013_1 1094755.MCO_00272 2.13e-13 74.7 COG4675@1|root,COG4675@2|Bacteria,1N0FZ@1224|Proteobacteria,2UDXB@28211|Alphaproteobacteria,48T3C@772|Bartonellaceae 28211|Alphaproteobacteria S Phage Tail Collar Domain - - - - - - - - - - - - Collar k59_352990_1 1165094.RINTHH_3920 9.43e-53 182.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_394495_1 1234888.K0A2J2_9VIRU 4.26e-41 151.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_579305_1 1439940.BAY1663_02360 7.01e-30 129.0 28JTG@1|root,2Z9IR@2|Bacteria,1PCXZ@1224|Proteobacteria,1SIJB@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF2793) - - - - - - - - - - - - DUF2793 k59_88027_2 1116375.VEJY3_09835 2.72e-26 100.0 COG2852@1|root,COG2852@2|Bacteria,1N2UX@1224|Proteobacteria,1TIHC@1236|Gammaproteobacteria,1XZ4M@135623|Vibrionales 135623|Vibrionales S Protein conserved in bacteria - - - - - - - - - - - - - k59_5728_1 348780.NP_0212A 2.16e-07 56.6 COG1061@1|root,arCOG00874@2157|Archaea,2XTYQ@28890|Euryarchaeota,23SWE@183963|Halobacteria 183963|Halobacteria K COG1061 DNA or RNA helicases of superfamily II rad25 - - - - - - - - - - - ERCC3_RAD25_C,ResIII k59_334578_1 1380600.AUYN01000007_gene3035 6.66e-09 64.7 COG1404@1|root,COG2866@1|root,COG1404@2|Bacteria,COG2866@2|Bacteria,4PM4C@976|Bacteroidetes,1IJJ4@117743|Flavobacteriia 976|Bacteroidetes O Belongs to the peptidase S8 family - - - - - - - - - - - - MAM,Peptidase_S8,fn3 k59_169654_1 691965.D4P7L7_9CAUD 3.25e-57 202.0 4QB9J@10239|Viruses,4QXFE@35237|dsDNA viruses no RNA stage,4QS1Z@28883|Caudovirales,4QN8F@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_558687_1 145579.H_BPPHM 1.02e-11 66.2 4QCA6@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_558687_2 105154.Q9MBU6_9VIRU 2.86e-156 465.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_519281_1 1128073.G9LQV6_9CIRC 6.07e-13 76.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_230157_2 1385658.U5KPZ6_9VIRU 3.1e-204 585.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_230157_4 2003327.REP_BPCHP 1.6e-11 72.8 4QCVK@10239|Viruses,4QUMV@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_251824_2 1609634.A0A0C5AFV4_9VIRU 1.7e-76 251.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_558690_1 1458357.BG58_31410 5.63e-13 77.0 COG5434@1|root,COG5434@2|Bacteria,1RCW1@1224|Proteobacteria,2W4G2@28216|Betaproteobacteria,1KBDM@119060|Burkholderiaceae 28216|Betaproteobacteria M Pectate lyase superfamily protein - - - - - - - - - - - - Pectate_lyase_3 k59_562329_1 1027273.GZ77_21170 9.67e-82 255.0 COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,1MVH7@1224|Proteobacteria,1S09Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria KL Belongs to the N(4) N(6)-methyltransferase family - - - - - - - - - - - - N6_N4_Mtase,ParBc k59_339513_1 756499.Desde_1078 1.05e-30 120.0 2CWXD@1|root,32T0J@2|Bacteria,1V83I@1239|Firmicutes,25DQF@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - AP2 k59_544556_1 1170562.Cal6303_2206 2.85e-09 62.8 COG1475@1|root,COG1475@2|Bacteria,1GR59@1117|Cyanobacteria,1HTTC@1161|Nostocales 1117|Cyanobacteria K DNA binding - - - - - - - - - - - - - k59_624917_1 272623.L111159 3.56e-06 55.1 COG1388@1|root,COG1388@2|Bacteria,1UI5H@1239|Firmicutes,4ID2P@91061|Bacilli,1YC5P@1357|Lactococcus 91061|Bacilli M Pfam:Cpl-7 - - - - - - - - - - - - CW_7 k59_624917_2 691965.D4P7C0_9CAUD 4.42e-32 115.0 4QDUR@10239|Viruses,4QVMY@35237|dsDNA viruses no RNA stage,4QU8R@28883|Caudovirales,4QKNQ@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_624917_3 691965.D4P7B9_9CAUD 3.81e-25 97.4 4QFDH@10239|Viruses,4QWV5@35237|dsDNA viruses no RNA stage,4QPB8@28883|Caudovirales,4QKNN@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_649095_2 1618257.A0A0C5IBI9_9CIRC 1.37e-53 183.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_29847_1 663278.Ethha_2633 3.94e-07 57.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia,3WGRT@541000|Ruminococcaceae 186801|Clostridia L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_297107_1 948071.S4S2D9_9CAUD 1.26e-34 136.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QNQ6@10744|Podoviridae 10744|Podoviridae S ribonucleoside-triphosphate reductase activity - - - - - - - - - - - - - k59_93836_2 105154.Q9MBU3_9VIRU 1.55e-07 58.2 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_93836_3 1385658.U5KPZ6_9VIRU 1.32e-136 413.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_259785_2 1379695.S5TNA9_9CIRC 3.41e-66 210.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_259789_2 65093.PCC7418_0823 3.88e-21 91.7 COG4902@1|root,COG4902@2|Bacteria,1G6BZ@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - DUF2202 k59_51728_2 1505225.A0A068CBG2_9CAUD 3.78e-51 171.0 4QBHW@10239|Viruses,4QTT7@28883|Caudovirales,4QJZQ@10662|Myoviridae 10662|Myoviridae S sequence-specific DNA binding transcription factor activity - - - - - - - - - - - - - k59_382813_3 485918.Cpin_3834 9.49e-44 152.0 COG0270@1|root,COG0270@2|Bacteria,4NRFG@976|Bacteroidetes,1IY5U@117747|Sphingobacteriia 976|Bacteroidetes L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_530551_2 1123322.KB904689_gene5035 2.16e-24 107.0 2DWRB@1|root,341IF@2|Bacteria,2ID68@201174|Actinobacteria 201174|Actinobacteria S Domain of unknown function (DUF5047) - - - - - - - - - - - - DUF5047 k59_99377_1 272569.rrnAC1831 4.09e-15 86.7 COG0417@1|root,arCOG00328@2157|Archaea,2XU1K@28890|Euryarchaeota,23RXE@183963|Halobacteria 183963|Halobacteria L COG0417 DNA polymerase elongation subunit (family B) polB1 - 2.7.7.7 ko:K02319 ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032 - - - DNA_pol_B,DNA_pol_B_exo1,Intein_splicing k59_608014_1 686340.Metal_1150 2.12e-12 74.7 COG2369@1|root,COG2369@2|Bacteria,1R40R@1224|Proteobacteria,1RPEA@1236|Gammaproteobacteria,1XGP8@135618|Methylococcales 135618|Methylococcales L PFAM Phage Mu protein F like protein - - - - - - - - - - - - Phage_Mu_F k59_629382_2 421052.F945_02819 1.06e-51 172.0 COG0302@1|root,COG0302@2|Bacteria,1MY3N@1224|Proteobacteria,1RMQM@1236|Gammaproteobacteria,3NKQ6@468|Moraxellaceae 1236|Gammaproteobacteria H GTP cyclohydrolase - - 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydroI k59_33418_1 1234888.K0A2J2_9VIRU 2.79e-33 131.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_130471_1 1172188.KB911820_gene2885 2.02e-108 336.0 COG0209@1|root,COG0209@2|Bacteria,2IC1H@201174|Actinobacteria 201174|Actinobacteria F Ribonucleotide reductase, barrel domain - - - - - - - - - - - - Ribonuc_red_lgC k59_313605_1 526227.Mesil_0490 2.21e-16 83.6 COG3378@1|root,COG3378@2|Bacteria,1WK78@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S Phage plasmid primase P4 family - - - ko:K06919 - - - - ko00000 - - - - k59_107948_2 1561065.A0A0B5A7I1_9CAUD 3.91e-18 86.3 4QAKM@10239|Viruses,4QPEF@28883|Caudovirales,4QKNE@10699|Siphoviridae 10699|Siphoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_191852_1 1234888.K0A2J2_9VIRU 2.71e-55 189.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_336941_1 1234888.K0A2J2_9VIRU 6.92e-70 226.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_542087_1 1986029.Q9MBM8_9VIRU 4.74e-26 106.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_354690_2 768670.Calni_0915 2.18e-24 99.0 COG0756@1|root,COG0756@2|Bacteria,2GFRX@200930|Deferribacteres 200930|Deferribacteres F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA dut - 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase k59_560475_3 691965.D4P7I8_9CAUD 8.31e-50 165.0 4QGJH@10239|Viruses,4QZ35@35237|dsDNA viruses no RNA stage,4QRZS@28883|Caudovirales,4QMAA@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_560475_5 691965.D4P7I3_9CAUD 4.39e-63 218.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_645293_1 620914.JH621246_gene2719 1.12e-29 123.0 2DMAC@1|root,32C43@2|Bacteria,4PMNJ@976|Bacteroidetes,1I3I7@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_439388_1 10752.A0MZC9_BPN4 6.59e-96 306.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_354696_1 172088.AUGA01000033_gene4641 8.55e-42 147.0 2CXZV@1|root,32T32@2|Bacteria,1N4R9@1224|Proteobacteria,2UM96@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_376851_1 1472912.A0A023NGU4_9CAUD 2.82e-27 119.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales 28883|Caudovirales S N-acetylmuramoyl-L-alanine amidase activity - GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019058,GO:0019062,GO:0022610,GO:0039638,GO:0044403,GO:0044406,GO:0044419,GO:0044423,GO:0044650,GO:0051704,GO:0098015,GO:0098024 - - - - - - - - - - - k59_27859_1 1224163.B841_09130 9.82e-05 50.8 COG0675@1|root,COG0675@2|Bacteria,2GM6K@201174|Actinobacteria 201174|Actinobacteria L Transposase - - - ko:K07496 - - - - ko00000 - - - OrfB_IS605,OrfB_Zn_ribbon k59_417917_1 5888.CAK83615 1.61e-05 56.2 KOG1975@1|root,KOG1975@2759|Eukaryota,3ZBU2@5878|Ciliophora 5878|Ciliophora A Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family - - 2.1.1.56 ko:K00565 ko03015,map03015 - R03805 RC00003,RC00336 ko00000,ko00001,ko01000,ko03019 - - - Pox_MCEL k59_499731_2 691965.D4P7L5_9CAUD 1.68e-32 116.0 4QG3V@10239|Viruses,4QW5T@35237|dsDNA viruses no RNA stage,4QSWE@28883|Caudovirales,4QM1Q@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_319068_1 1397284.AYMN01000028_gene3417 1.56e-17 93.6 COG0749@1|root,COG0749@2|Bacteria,1MWX7@1224|Proteobacteria,1S0Q1@1236|Gammaproteobacteria 1236|Gammaproteobacteria L ORF located using Glimmer RBSfinder - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A,DNA_pol_A_exo1 k59_51101_1 572477.Alvin_0895 5.78e-36 139.0 COG4983@1|root,COG4983@2|Bacteria,1N636@1224|Proteobacteria,1RZVN@1236|Gammaproteobacteria,1WZ8Z@135613|Chromatiales 1236|Gammaproteobacteria T Protein of unknown function (DUF3987) - - - - - - - - - - - - DUF3987 k59_529291_1 1173762.S4TT67_9CAUD 3.7e-66 218.0 4QCT5@10239|Viruses,4QYJH@35237|dsDNA viruses no RNA stage,4QTPG@28883|Caudovirales,4QNK2@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_529291_2 1051675.G0YQH7_9CAUD 3.46e-57 197.0 4QGGR@10239|Viruses,4QZHR@35237|dsDNA viruses no RNA stage,4QUGZ@28883|Caudovirales,4QNY3@10744|Podoviridae 10744|Podoviridae S viral capsid - - - - - - - - - - - - - k59_178202_3 1379695.S5TNA9_9CIRC 3.34e-08 55.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_401851_1 153721.MYP_3637 8.78e-11 74.7 COG4733@1|root,COG4733@2|Bacteria,4NTXR@976|Bacteroidetes,47SSC@768503|Cytophagia 976|Bacteroidetes S Concanavalin A-like lectin/glucanases superfamily - - - - - - - - - - - - CHU_C,Laminin_G_3 k59_98188_2 105154.Q9MBU6_9VIRU 3.57e-48 177.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_278661_1 1197906.CAJQ02000016_gene198 8.06e-16 82.4 28JTG@1|root,2Z9IR@2|Bacteria,1R0GC@1224|Proteobacteria,2TURR@28211|Alphaproteobacteria,3JUCC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF2793) - - - - - - - - - - - - DUF2793 k59_51114_2 1173709.M3VMK9_9CIRC 1.1e-39 141.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_215025_1 1245469.S58_00030 5.25e-29 120.0 COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,2TSRZ@28211|Alphaproteobacteria,3JUE8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 k59_51126_1 31964.CMS0848 1.77e-12 67.8 arCOG05626@1|root,30CNA@2|Bacteria,2I38B@201174|Actinobacteria,4FS6S@85023|Microbacteriaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_237074_1 714943.Mucpa_4104 1.76e-12 75.5 COG2373@1|root,COG3210@1|root,COG5184@1|root,COG2373@2|Bacteria,COG3210@2|Bacteria,COG5184@2|Bacteria,4NKG5@976|Bacteroidetes 976|Bacteroidetes U Psort location Extracellular, score 9.64 - - - - - - - - - - - - CHU_C,HYR,SASA k59_549720_1 1121097.JCM15093_3233 2.07e-34 139.0 COG0863@1|root,COG0863@2|Bacteria,4PMGB@976|Bacteroidetes,2G0C7@200643|Bacteroidia,4APG6@815|Bacteroidaceae 976|Bacteroidetes L Belongs to the N(4) N(6)-methyltransferase family - - - - - - - - - - - - - k59_259558_1 1280.SAXN108_2150 4.25e-06 55.1 COG0209@1|root,COG1372@1|root,COG0209@2|Bacteria,COG1372@2|Bacteria,1TPFH@1239|Firmicutes,4H9X0@91061|Bacilli,4H0KV@90964|Staphylococcaceae 91061|Bacilli FL Hint (Hedgehog/Intein) domain C-terminal region nrdE - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - iYO844.BSU17380 RNR_N,Ribonuc_red_lgC,Ribonuc_red_lgN k59_381958_1 1173709.M3VMK9_9CIRC 6.74e-51 172.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_634670_1 426114.THI_1427 0.000225 48.9 COG1846@1|root,COG1846@2|Bacteria 2|Bacteria K DNA-binding transcription factor activity - - - - - - - - - - - - MarR,MarR_2 k59_143153_1 933262.AXAM01000071_gene2218 9.32e-19 87.4 28XPA@1|root,2ZJK5@2|Bacteria,1P9T2@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_79957_1 1286632.P278_33640 2.15e-124 354.0 28HGS@1|root,2Z7SJ@2|Bacteria,4NERU@976|Bacteroidetes,1HZIZ@117743|Flavobacteriia 976|Bacteroidetes S Major spike protein (G protein) - - - - - - - - - - - - Phage_G k59_79957_2 1270196.JCKI01000013_gene3205 0.0 889.0 28IN7@1|root,2Z8NM@2|Bacteria,4NHTH@976|Bacteroidetes 976|Bacteroidetes S Capsid protein (F protein) - - - - - - - - - - - - Phage_F k59_79957_3 1286632.P278_33670 1.35e-19 79.0 2EFW9@1|root,339NJ@2|Bacteria,4P71N@976|Bacteroidetes,1I6VT@117743|Flavobacteriia 976|Bacteroidetes S Microvirus J protein - - - - - - - - - - - - Microvir_J k59_79957_4 1288298.rosmuc_01661 4.9e-103 298.0 28HVF@1|root,2Z81Q@2|Bacteria,1NZPF@1224|Proteobacteria 1224|Proteobacteria S Bacteriophage scaffolding protein D - - - - - - - - - - - - gpD k59_79957_5 1270196.JCKI01000013_gene3202 4.42e-56 174.0 2AGWD@1|root,3174S@2|Bacteria 2|Bacteria S Phage protein C - - - - - - - - - - - - Phage_C k59_79957_6 1286632.P278_33700 0.0 1035.0 28I9J@1|root,2Z8C8@2|Bacteria,4P06R@976|Bacteroidetes,1I7XB@117743|Flavobacteriia 976|Bacteroidetes S Bacteriophage replication gene A protein (GPA) - - - - - - - - - - - - Phage_GPA k59_79957_7 1288298.rosmuc_01659 6.62e-188 527.0 2DBBW@1|root,2Z8AR@2|Bacteria,1R492@1224|Proteobacteria,2UP8C@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Microvirus H protein (pilot protein) - - - - - - - - - - - - Microvir_H k59_79961_1 1234888.K0A2J2_9VIRU 5.11e-58 196.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_203244_1 1692242.A0A0K1RL37_9CIRC 1.49e-60 198.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_471423_1 1395516.PMO01_03075 1.11e-18 86.3 2DP75@1|root,330U8@2|Bacteria,1N8XA@1224|Proteobacteria,1SCZN@1236|Gammaproteobacteria 1236|Gammaproteobacteria S HNH endonuclease - - - - - - - - - - - - AP2,HNH_3 k59_612228_5 318464.IO99_00635 6.37e-08 63.5 COG5281@1|root,COG5281@2|Bacteria,1TPWF@1239|Firmicutes,24A8R@186801|Clostridia,36GW3@31979|Clostridiaceae 186801|Clostridia S tape measure - - - - - - - - - - - - - k59_184507_5 1210884.HG799463_gene10348 9.29e-11 67.8 COG2264@1|root,COG2264@2|Bacteria 2|Bacteria J protein methyltransferase activity prmA1 - - ko:K02687 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_31,PrmA k59_117727_5 753084.F4YCI4_9CAUD 7.62e-124 368.0 4QAIK@10239|Viruses,4QUPH@35237|dsDNA viruses no RNA stage,4QS4V@28883|Caudovirales,4QKNC@10699|Siphoviridae 10699|Siphoviridae S hydrolase activity - - - - - - - - - - - - - k59_117727_8 202952.BBLI01000126_gene3983 1.39e-47 162.0 2CS3D@1|root,32SQ7@2|Bacteria,1N5BY@1224|Proteobacteria,1S9EX@1236|Gammaproteobacteria,3NKGG@468|Moraxellaceae 1236|Gammaproteobacteria S ERF superfamily - - - - - - - - - - - - ERF k59_510275_1 1366055.S5MLS6_9CAUD 6.84e-32 117.0 4QE7X@10239|Viruses,4QVF0@35237|dsDNA viruses no RNA stage,4QPUM@28883|Caudovirales,4QN8I@10699|Siphoviridae 10699|Siphoviridae S Cytidine and deoxycytidylate deaminase zinc-binding region - - - - - - - - - - - - - k59_327023_3 563192.HMPREF0179_02963 1.12e-07 63.5 COG1196@1|root,COG3941@1|root,COG1196@2|Bacteria,COG3941@2|Bacteria 2|Bacteria O tape measure - - - ko:K03529 - - - - ko00000,ko03036 - - - PhageMin_Tail,Tape_meas_lam_C k59_409078_2 1327982.R9ZZE9_9CAUD 1.8e-61 205.0 4QGM3@10239|Viruses,4QYG4@35237|dsDNA viruses no RNA stage,4QPTC@28883|Caudovirales,4QMVS@10699|Siphoviridae 10699|Siphoviridae S oxidoreductase activity - - - - - - - - - - - - - k59_391617_1 1122917.KB899659_gene5165 9.36e-16 87.8 COG1643@1|root,COG1643@2|Bacteria,1TPET@1239|Firmicutes,4HE8W@91061|Bacilli,26U7B@186822|Paenibacillaceae 91061|Bacilli L ATP-dependent helicase hrpB - 3.6.4.13 ko:K03579 - - - - ko00000,ko01000 - - - DEAD,HA2,Helicase_C,HrpB_C k59_42544_1 105154.Q9MBU6_9VIRU 1.25e-106 325.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_42544_2 105154.Q9MBU3_9VIRU 5.87e-10 64.3 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_474052_1 691965.D4P7I3_9CAUD 3.96e-105 341.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_555779_1 2003327.CAPSD_BPCHP 1.51e-100 317.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_515472_1 1385658.U5KPZ6_9VIRU 8.22e-88 277.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_371242_2 484019.THA_1171 9.56e-05 51.6 COG0642@1|root,COG2205@2|Bacteria,2GEGV@200918|Thermotogae 200918|Thermotogae T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - HATPase_c k59_309215_5 1234888.K0A2J2_9VIRU 4.83e-136 405.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_227511_1 1122175.ATXU01000006_gene1928 1.32e-09 59.3 COG0270@1|root,COG0270@2|Bacteria,2GNB2@201174|Actinobacteria,4FS7A@85023|Microbacteriaceae 201174|Actinobacteria L DNA (cytosine-5-)-methyltransferase activity - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_330773_1 105154.Q9MBU6_9VIRU 8.03e-77 246.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_84444_2 1354314.CHV_a0505 1.31e-35 127.0 COG2131@1|root,COG2131@2|Bacteria,4NM48@976|Bacteroidetes,47P6P@768503|Cytophagia 976|Bacteroidetes F PFAM Cytidine and deoxycytidylate deaminase zinc-binding region comEB - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 k59_125106_1 551275.KB899546_gene2190 9.73e-06 52.8 COG0524@1|root,COG0524@2|Bacteria,1MUUC@1224|Proteobacteria,2TS9D@28211|Alphaproteobacteria,43WJU@69657|Hyphomonadaceae 28211|Alphaproteobacteria G COG0524 Sugar kinases, ribokinase family pfkB - 2.7.1.20,2.7.1.4 ko:K00847,ko:K00856 ko00051,ko00230,ko00500,ko00520,ko01100,map00051,map00230,map00500,map00520,map01100 - R00185,R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB k59_125106_2 1227349.C170_28128 2.58e-10 61.6 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,4HD42@91061|Bacilli,271WS@186822|Paenibacillaceae 91061|Bacilli G Fructose-bisphosphate aldolase - - 4.1.2.13 ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 - - - F_bP_aldolase k59_2343_1 948071.S4S2N2_9CAUD 1.93e-07 53.1 4QH10@10239|Viruses,4QVVN@35237|dsDNA viruses no RNA stage,4QSY9@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_555803_1 1692255.A0A0K1RL52_9CIRC 6.74e-78 244.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_248703_3 97139.C824_00252 6.52e-05 56.6 COG4733@1|root,COG5492@1|root,COG4733@2|Bacteria,COG5492@2|Bacteria 2|Bacteria N domain, Protein - - 3.2.1.81 ko:K01219,ko:K20276 ko02024,map02024 - - - ko00000,ko00001,ko01000 - - - BACON,Big_2,Big_4,CARDB,CBM_6,Laminin_G_3,Lipase_GDSL_2,M60-like_N,PKD,Peptidase_M60,Phage-tail_3,SLH,TSP_3 k59_206597_2 1618260.A0A0C5I2C5_9CIRC 3.48e-40 148.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_231206_1 476272.RUMHYD_01966 2.94e-20 84.7 2EK5K@1|root,33DW0@2|Bacteria,1UU54@1239|Firmicutes,255II@186801|Clostridia 186801|Clostridia S Putative phage holin Dp-1 - - - - - - - - - - - - Phage_holin_Dp1 k59_6915_1 1094551.MEC_00712 1.34e-11 73.2 COG4675@1|root,COG4675@2|Bacteria,1N0FZ@1224|Proteobacteria,2UDXB@28211|Alphaproteobacteria,48T3C@772|Bartonellaceae 28211|Alphaproteobacteria S Phage Tail Collar Domain - - - - - - - - - - - - Collar k59_107413_1 431943.CKL_0424 3.59e-15 81.3 COG0603@1|root,COG0603@2|Bacteria,1TP4Z@1239|Firmicutes,2497A@186801|Clostridia,36DMD@31979|Clostridiaceae 186801|Clostridia F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) queC - 6.3.4.20 ko:K06920 ko00790,ko01100,map00790,map01100 - R09978 RC00959 ko00000,ko00001,ko01000,ko03016 - - - QueC k59_293700_1 643867.Ftrac_1210 8.2e-17 80.9 COG1484@1|root,COG1484@2|Bacteria,4NFYG@976|Bacteroidetes,47Q3D@768503|Cytophagia 976|Bacteroidetes L DNA-dependent DNA replication - - - - - - - - - - - - - k59_130221_2 1395516.PMO01_05050 2.14e-06 50.1 2EI4V@1|root,33BW7@2|Bacteria,1NN3Z@1224|Proteobacteria 1224|Proteobacteria S Protein of unknwon function (DUF3310) - - - - - - - - - - - - DUF3310 k59_439086_1 7668.SPU_022516-tr 1.53e-11 69.3 COG0210@1|root,KOG2108@2759|Eukaryota,396PD@33154|Opisthokonta,3BHJH@33208|Metazoa,3CTGZ@33213|Bilateria 33208|Metazoa L response to intra-S DNA damage checkpoint signaling FBXO18 GO:0000018,GO:0000151,GO:0000724,GO:0000725,GO:0000737,GO:0000785,GO:0001932,GO:0001934,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003690,GO:0003697,GO:0003824,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006275,GO:0006281,GO:0006282,GO:0006302,GO:0006308,GO:0006310,GO:0006464,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0008156,GO:0008219,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009607,GO:0009719,GO:0009889,GO:0009890,GO:0009892,GO:0009893,GO:0009966,GO:0009967,GO:0009987,GO:0010556,GO:0010558,GO:0010562,GO:0010569,GO:0010604,GO:0010605,GO:0010646,GO:0010647,GO:0010941,GO:0010942,GO:0015616,GO:0016043,GO:0016462,GO:0016567,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019005,GO:0019219,GO:0019220,GO:0019222,GO:0019439,GO:0019538,GO:0023051,GO:0023056,GO:0031297,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031399,GO:0031401,GO:0031461,GO:0032268,GO:0032270,GO:0032392,GO:0032446,GO:0032508,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0034655,GO:0035561,GO:0035562,GO:0036211,GO:0042325,GO:0042327,GO:0042623,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043138,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043412,GO:0044092,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0045005,GO:0045738,GO:0045910,GO:0045934,GO:0045937,GO:0046483,GO:0046700,GO:0048478,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051098,GO:0051100,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051246,GO:0051247,GO:0051276,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070647,GO:0071103,GO:0071216,GO:0071495,GO:0071704,GO:0071840,GO:0072396,GO:0072402,GO:0072423,GO:0072429,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0090305,GO:0090329,GO:0097159,GO:0140097,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1902229,GO:1902231,GO:1902494,GO:1902531,GO:1902533,GO:1990234,GO:2000042,GO:2000104,GO:2000112,GO:2000113,GO:2000779,GO:2000780,GO:2001020,GO:2001021,GO:2001022,GO:2001233,GO:2001235,GO:2001242,GO:2001244 3.6.4.12 ko:K10300 - - - - ko00000,ko01000,ko04121 - - - AAA_19,F-box,F-box-like,UvrD-helicase,UvrD_C k59_541784_2 107636.JQNK01000009_gene1975 2.75e-16 75.5 2AKUS@1|root,31BMX@2|Bacteria,1NZDG@1224|Proteobacteria,2UTNA@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_480980_1 931276.Cspa_c57170 5.14e-83 268.0 COG5410@1|root,COG5410@2|Bacteria,1TSMG@1239|Firmicutes,248S7@186801|Clostridia,36FFT@31979|Clostridiaceae 186801|Clostridia S TIGRFAM Phage - - - - - - - - - - - - Terminase_6,Terminase_6C k59_68528_1 1540098.A0A0A0RQI2_9CAUD 3.37e-66 227.0 4QB5I@10239|Viruses,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_580936_1 34839.XP_005381992.1 8.43e-52 181.0 COG1678@1|root,KOG1567@2759|Eukaryota,38B80@33154|Opisthokonta,3B9U0@33208|Metazoa,3CT3A@33213|Bilateria,484EH@7711|Chordata,48X4B@7742|Vertebrata,3JDGH@40674|Mammalia,35JTK@314146|Euarchontoglires,4PZSZ@9989|Rodentia 33208|Metazoa F Ribonucleoside-diphosphate reductase subunit M2 B RRM2B GO:0000002,GO:0001655,GO:0001822,GO:0003008,GO:0003014,GO:0003674,GO:0003824,GO:0004748,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005829,GO:0005971,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006264,GO:0006281,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006919,GO:0006950,GO:0006974,GO:0006979,GO:0006996,GO:0007005,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009141,GO:0009165,GO:0009200,GO:0009262,GO:0009263,GO:0009790,GO:0009792,GO:0009893,GO:0009966,GO:0009968,GO:0009987,GO:0010604,GO:0010646,GO:0010648,GO:0010941,GO:0010942,GO:0010950,GO:0010952,GO:0016043,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019222,GO:0019438,GO:0019637,GO:0023051,GO:0023057,GO:0030162,GO:0031323,GO:0031325,GO:0031974,GO:0031981,GO:0032042,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042981,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043085,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043280,GO:0043281,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045862,GO:0046483,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048731,GO:0048856,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051336,GO:0051345,GO:0051716,GO:0052547,GO:0052548,GO:0055086,GO:0055114,GO:0060255,GO:0060548,GO:0061731,GO:0065007,GO:0065009,GO:0070013,GO:0071704,GO:0071840,GO:0072001,GO:0080090,GO:0090304,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576,GO:1901796,GO:1901797,GO:1902253,GO:1902254,GO:1902494,GO:1902531,GO:1902532,GO:1990204,GO:2000116,GO:2001056,GO:2001233,GO:2001234,GO:2001242,GO:2001243 1.17.4.1 ko:K10808 ko00230,ko00240,ko00480,ko00983,ko01100,ko04115,map00230,map00240,map00480,map00983,map01100,map04115 M00053 R02017,R02019,R02024,R08363,R08364,R11893 RC00613,RC01003 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_sm k59_488587_6 305700.B447_10643 9.53e-31 114.0 COG2197@1|root,COG2197@2|Bacteria,1NA3X@1224|Proteobacteria,2VW90@28216|Betaproteobacteria 28216|Betaproteobacteria KT HNH endonuclease - - - - - - - - - - - - HNH_3 k59_318909_1 375286.mma_2189 7.15e-32 125.0 2CWXD@1|root,32T0J@2|Bacteria,1N3Z7@1224|Proteobacteria,2WBUY@28216|Betaproteobacteria,477U0@75682|Oxalobacteraceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_446312_1 649639.Bcell_1685 0.000526 50.8 COG0553@1|root,COG0553@2|Bacteria,1TQ5E@1239|Firmicutes,4H9WB@91061|Bacilli,1ZAR5@1386|Bacillus 91061|Bacilli L COG0553 Superfamily II DNA RNA helicases, SNF2 family yqhH - - - - - - - - - - - Helicase_C,SNF2_N k59_299724_1 1234888.K0A2J2_9VIRU 5.39e-56 193.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_32495_1 1122201.AUAZ01000026_gene1209 2.69e-55 186.0 2C6N9@1|root,32RHI@2|Bacteria,1P488@1224|Proteobacteria,1SUTU@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_488608_4 1122173.AXVL01000045_gene2105 2.02e-60 207.0 COG1475@1|root,COG2189@1|root,COG1475@2|Bacteria,COG2189@2|Bacteria,37ATR@32066|Fusobacteria 32066|Fusobacteria KL ParB-like nuclease domain - - - - - - - - - - - - N6_N4_Mtase,ParBc k59_73673_1 469660.A8HP51_9CAUD 1.21e-64 203.0 4QBFR@10239|Viruses,4QV1E@35237|dsDNA viruses no RNA stage,4QPRX@28883|Caudovirales,4QNJQ@10744|Podoviridae 10744|Podoviridae S ERF superfamily - - - - - - - - - - - - - k59_178078_1 880073.Calab_1470 6.78e-45 154.0 COG0270@1|root,COG0270@2|Bacteria 2|Bacteria L DNA (cytosine-5-)-methyltransferase activity dcm - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_97975_3 488538.SAR116_0386 1.18e-37 133.0 COG1351@1|root,COG1351@2|Bacteria,1MWY8@1224|Proteobacteria,2TTER@28211|Alphaproteobacteria,4BRKK@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant thyX - 2.1.1.148 ko:K03465 ko00240,ko00670,ko01100,map00240,map00670,map01100 - R06613 RC00022,RC00332 ko00000,ko00001,ko01000 - - - Thy1 k59_464732_1 443144.GM21_0805 2.83e-12 74.7 COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,42N7I@68525|delta/epsilon subdivisions,2WJG8@28221|Deltaproteobacteria 28221|Deltaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_3,Phage_integrase k59_606883_1 488538.SAR116_2344 1.76e-06 55.1 2EBZ0@1|root,335Y9@2|Bacteria,1NF45@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_628326_1 502558.EGYY_00600 5.22e-33 123.0 COG0270@1|root,COG0270@2|Bacteria,2HTYU@201174|Actinobacteria,4CWG1@84998|Coriobacteriia 84998|Coriobacteriia L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_381824_3 1692257.A0A0K1RL39_9CIRC 5.79e-22 101.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_236951_1 883078.HMPREF9695_04259 2.63e-07 58.2 COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,2U05W@28211|Alphaproteobacteria,3JV47@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_3,Phage_int_SAM_3,Phage_integrase k59_504400_2 366602.Caul_4287 5.81e-19 84.7 COG1715@1|root,COG1715@2|Bacteria,1Q2VY@1224|Proteobacteria,2TVMP@28211|Alphaproteobacteria 28211|Alphaproteobacteria L restriction endonuclease mrr - - ko:K07448 - - - - ko00000,ko02048 - - - Mrr_N,Mrr_cat k59_278581_1 697282.Mettu_3886 5.3e-82 273.0 COG1749@1|root,COG2319@1|root,COG2372@1|root,COG1749@2|Bacteria,COG2319@2|Bacteria,COG2372@2|Bacteria,1MWJA@1224|Proteobacteria,1S1AJ@1236|Gammaproteobacteria,1XF66@135618|Methylococcales 135618|Methylococcales N WD40 repeat, subgroup - - - - - - - - - - - - Big_5,DUF4082,WD40 k59_51399_1 1692252.A0A0K1RL35_9CIRC 2.52e-59 193.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_471166_1 1267533.KB906733_gene3133 9.49e-36 130.0 COG5549@1|root,COG5549@2|Bacteria,3Y7J6@57723|Acidobacteria,2JMQZ@204432|Acidobacteriia 204432|Acidobacteriia O Zinc-dependent metalloprotease - - - - - - - - - - - - - k59_220097_1 910964.GEAM_4248 3.44e-06 54.3 COG1196@1|root,COG1196@2|Bacteria,1MU81@1224|Proteobacteria,1RS6P@1236|Gammaproteobacteria 1236|Gammaproteobacteria D tail length tape measure - - - - - - - - - - - - TMP_2,Tape_meas_lam_C k59_612091_1 1385658.U5KPZ6_9VIRU 1.4e-95 301.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_571263_3 1185652.USDA257_c46250 1e-29 116.0 2C3WM@1|root,3002C@2|Bacteria,1R3MS@1224|Proteobacteria,2U048@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Domain of unknown function (DUF4326) - - - - - - - - - - - - DUF4326 k59_38528_1 888055.HMPREF9015_01905 7.54e-14 74.7 COG3935@1|root,COG3935@2|Bacteria,37ANW@32066|Fusobacteria 32066|Fusobacteria L Helix-turn-helix domain - - - - - - - - - - - - HTH_36 k59_284812_1 1443125.Z962_p0001 3.97e-12 72.0 COG1961@1|root,COG1961@2|Bacteria,1TS5B@1239|Firmicutes,248MZ@186801|Clostridia,36DMB@31979|Clostridiaceae 186801|Clostridia L resolvase - - - - - - - - - - - - Recombinase,Resolvase,Zn_ribbon_recom k59_612621_1 1133849.O3I_018095 8.68e-26 111.0 COG0392@1|root,COG0671@1|root,COG3642@1|root,COG0392@2|Bacteria,COG0671@2|Bacteria,COG3642@2|Bacteria,2GMAV@201174|Actinobacteria,4FXZC@85025|Nocardiaceae 201174|Actinobacteria IT Lysylphosphatidylglycerol synthase TM region - - 3.6.1.27 ko:K07027,ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011,ko02000 4.D.2 - - LPG_synthase_TM,PAP2 k59_430008_1 981335.G4W934_9CAUD 3.77e-58 188.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales 28883|Caudovirales S N-methyltransferase activity - - - - - - - - - - - - - k59_389513_3 1445726.W0LKB6_9CAUD 1.14e-12 67.8 4QB0C@10239|Viruses,4QW7S@35237|dsDNA viruses no RNA stage,4QPK3@28883|Caudovirales,4QKQC@10699|Siphoviridae 10699|Siphoviridae S magnesium ion binding - - - - - - - - - - - - - k59_635393_1 1123401.JHYQ01000003_gene2190 2.06e-06 56.6 COG0741@1|root,COG2911@1|root,COG0741@2|Bacteria,COG2911@2|Bacteria,1N9K5@1224|Proteobacteria,1SE7W@1236|Gammaproteobacteria 1236|Gammaproteobacteria D lytic transglycosylase activity - - - - - - - - - - - - - k59_83907_2 748224.HMPREF9436_02205 5.48e-08 60.8 COG0714@1|root,COG0714@2|Bacteria,1U8NZ@1239|Firmicutes,248X1@186801|Clostridia,3WHAV@541000|Ruminococcaceae 186801|Clostridia S AAA domain (dynein-related subfamily) - - - - - - - - - - - - AAA,AAA_5 k59_473721_1 118173.KB235914_gene2661 1.54e-60 196.0 COG0603@1|root,COG0603@2|Bacteria,1G24C@1117|Cyanobacteria,1H9ZJ@1150|Oscillatoriales 1117|Cyanobacteria F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) queC - 6.3.4.20 ko:K06920 ko00790,ko01100,map00790,map01100 - R09978 RC00959 ko00000,ko00001,ko01000,ko03016 - - - QueC k59_268397_3 526222.Desal_1848 3.33e-21 90.5 2DMPB@1|root,32SV8@2|Bacteria,1NHUE@1224|Proteobacteria,430VU@68525|delta/epsilon subdivisions,2WW0U@28221|Deltaproteobacteria,2MCJ3@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_268397_4 1392490.JHZX01000001_gene1735 1.24e-64 239.0 2EAST@1|root,334US@2|Bacteria,4NRGD@976|Bacteroidetes,1I583@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_268397_6 1406840.Q763_17125 4.59e-61 207.0 COG0740@1|root,COG0740@2|Bacteria,4NNEB@976|Bacteroidetes,1IN9D@117743|Flavobacteriia,2NYMF@237|Flavobacterium 976|Bacteroidetes OU Clp protease - - 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease k59_145181_2 439809.A5YK43_9CAUD 1.18e-10 64.3 4QAKE@10239|Viruses,4QUP7@35237|dsDNA viruses no RNA stage,4QPCE@28883|Caudovirales 28883|Caudovirales S endonuclease activity - - - - - - - - - - - - - k59_514747_1 870187.Thini_0411 7.3e-08 59.7 2EP1Y@1|root,33GNT@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_535119_1 1122962.AULH01000018_gene333 8.69e-13 79.0 COG4733@1|root,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria,2TV2W@28211|Alphaproteobacteria,36XJ8@31993|Methylocystaceae 28211|Alphaproteobacteria S COG4733 Phage-related protein, tail component - - - - - - - - - - - - Phage-tail_3 k59_83912_2 706587.Desti_0995 4.29e-18 95.9 COG0358@1|root,COG3378@1|root,COG0358@2|Bacteria,COG3378@2|Bacteria,1MV7I@1224|Proteobacteria,42QE4@68525|delta/epsilon subdivisions,2WM1X@28221|Deltaproteobacteria 28221|Deltaproteobacteria L Phage plasmid primase, P4 family - - - ko:K06919 - - - - ko00000 - - - D5_N,Pox_D5,Toprim_2,zf-CHC2 k59_637719_1 1556290.A0A0A0RSX4_9CAUD 1.39e-59 199.0 4QBP9@10239|Viruses,4QPQF@28883|Caudovirales,4QMF3@10699|Siphoviridae 10699|Siphoviridae S Domain of unknown function (DUF932) - - - - - - - - - - - - - k59_411815_1 2342.SOPEG_2715 2.36e-08 62.4 COG4397@1|root,COG4397@2|Bacteria,1MWX8@1224|Proteobacteria,1RR4A@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Mu-like prophage major head subunit gpT - - - - - - - - - - - - Mu-like_gpT k59_288583_4 2003327.CAPSD_BPCHP 2.41e-50 180.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_5109_4 1385658.U5KNR1_9VIRU 3.65e-67 220.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_5109_6 1609634.A0A0C5AFV4_9VIRU 1.87e-42 153.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_436384_2 767434.Fraau_1461 3.93e-09 57.8 COG1694@1|root,COG1694@2|Bacteria,1N3XF@1224|Proteobacteria,1SSUP@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Mazg nucleotide pyrophosphohydrolase - - - - - - - - - - - - - k59_352498_1 1492922.GY26_01890 1.8e-139 411.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,1RP8Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria K terminase - - - - - - - - - - - - Terminase_1 k59_87348_5 211114.JOEF01000001_gene7051 2.53e-35 136.0 COG0330@1|root,COG0330@2|Bacteria,2IGTF@201174|Actinobacteria 201174|Actinobacteria O SPFH domain / Band 7 family - - - - - - - - - - - - Band_7 k59_24863_4 1385935.N836_23450 5.5e-07 57.8 COG0845@1|root,COG2227@1|root,COG0845@2|Bacteria,COG2227@2|Bacteria,1G3EJ@1117|Cyanobacteria,1HA8B@1150|Oscillatoriales 1117|Cyanobacteria H Methionine biosynthesis protein MetW - - - - - - - - - - - - Methyltransf_11,Methyltransf_23 k59_24863_5 67593.Physo155230 2.94e-28 130.0 COG3914@1|root,KOG4626@2759|Eukaryota,3QC0T@4776|Peronosporales 4776|Peronosporales GOT Glycosyl transferase family 41 - - - - - - - - - - - - Glyco_transf_41,TPR_16 k59_24863_7 649747.HMPREF0083_01683 3.59e-14 81.6 COG4373@1|root,COG4373@2|Bacteria,1TQNK@1239|Firmicutes,4HDES@91061|Bacilli,26WPR@186822|Paenibacillaceae 91061|Bacilli S Mu-like prophage FluMu protein gp28 gp17a - - - - - - - - - - - Terminase_6,Terminase_6C k59_436388_1 2003327.CAPSD_BPCHP 1.79e-34 135.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_105923_1 1460634.JCM19037_3684 1.23e-29 116.0 COG0270@1|root,COG0270@2|Bacteria,1TPNE@1239|Firmicutes,4HHQR@91061|Bacilli 91061|Bacilli H C-5 cytosine-specific DNA methylase - - - - - - - - - - - - DNA_methylase k59_251537_2 414996.IL38_24185 1.62e-05 50.4 COG1372@1|root,COG1372@2|Bacteria,2IABP@201174|Actinobacteria 201174|Actinobacteria L Participates in initiation and elongation during chromosome replication - - - - - - - - - - - - - k59_436750_1 1692246.A0A0K1RLM8_9CIRC 2.35e-15 77.0 4QBFZ@10239|Viruses,4QUKU@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_539404_1 1788454.A0A190WHE4_9CIRC 2.82e-37 136.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_5423_1 525257.HMPREF0204_11331 2.32e-18 85.1 2DNSD@1|root,32YWU@2|Bacteria,4PK7A@976|Bacteroidetes,1IBMQ@117743|Flavobacteriia,3ZU2R@59732|Chryseobacterium 976|Bacteroidetes L HNH endonuclease - - - - - - - - - - - - HNH_3 k59_5423_2 1540097.A0A0A0YU70_9CAUD 2.89e-14 72.4 4QAKM@10239|Viruses,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_373878_1 1173709.M3VMK9_9CIRC 6.96e-41 141.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_436752_2 1618248.A0A0C5IB82_9CIRC 5.58e-60 201.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_642146_1 1157708.KB907450_gene5414 1.18e-50 167.0 COG1403@1|root,COG1403@2|Bacteria 2|Bacteria V endonuclease activity - - - - - - - - - - - - HNH,HNH_5 k59_5435_1 504346.PRO_0000326456 2.72e-07 60.1 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales 28883|Caudovirales S N-acetylmuramoyl-L-alanine amidase activity - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019028,GO:0019058,GO:0019062,GO:0022610,GO:0042802,GO:0044403,GO:0044406,GO:0044419,GO:0044423,GO:0044650,GO:0051704,GO:0098015,GO:0098024 - - - - - - - - - - - k59_582495_2 622312.ROSEINA2194_01264 3.55e-36 133.0 COG0270@1|root,COG0270@2|Bacteria,1VSZI@1239|Firmicutes,24YBG@186801|Clostridia 186801|Clostridia L C-5 cytosine-specific DNA methylase - - - - - - - - - - - - DNA_methylase k59_460235_1 1234888.K0A2J2_9VIRU 1.81e-61 206.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_561843_1 224719.Abm4_0443 1.02e-05 52.0 COG0582@1|root,arCOG01241@2157|Archaea,2XV3E@28890|Euryarchaeota,23NKR@183925|Methanobacteria 183925|Methanobacteria L Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules xerA - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_integrase k59_647320_1 1125779.HMPREF1219_00167 7.46e-19 95.1 COG3953@1|root,COG5412@1|root,COG3953@2|Bacteria,COG5412@2|Bacteria,2I5CG@201174|Actinobacteria,22KNY@1653|Corynebacteriaceae 201174|Actinobacteria M heme binding - - - - - - - - - - - - SLT k59_582499_1 909297.G8CLB5_9CAUD 9.72e-06 53.5 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_274692_2 941449.dsx2_3151 1.6e-16 78.2 COG4725@1|root,COG4725@2|Bacteria,1R553@1224|Proteobacteria,42QPR@68525|delta/epsilon subdivisions,2WN79@28221|Deltaproteobacteria,2MEB7@213115|Desulfovibrionales 28221|Deltaproteobacteria KT MT-A70 - - - - - - - - - - - - MT-A70 k59_132129_1 329381.D9ICQ3_9CAUD 1.65e-13 73.9 4QAKE@10239|Viruses,4QUP7@35237|dsDNA viruses no RNA stage,4QPCE@28883|Caudovirales,4QI56@10662|Myoviridae 10662|Myoviridae S nucleic acid binding - - - - - - - - - - - - - k59_397800_3 1410620.SHLA_4c002050 0.000105 45.4 COG1694@1|root,COG1694@2|Bacteria,1N3XF@1224|Proteobacteria,2UG4F@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Mazg nucleotide pyrophosphohydrolase - - - - - - - - - - - - - k59_377649_1 1034347.CAHJ01000080_gene1214 3.9e-06 52.0 2DPIQ@1|root,3328X@2|Bacteria,1VFYC@1239|Firmicutes,4HNHQ@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - AP2 k59_377652_1 1176423.I6S776_9VIRU 1.93e-27 107.0 4QE7X@10239|Viruses,4QVF0@35237|dsDNA viruses no RNA stage 10239|Viruses S Cytidine and deoxycytidylate deaminase zinc-binding region - - - - - - - - - - - - - k59_624423_1 445970.ALIPUT_02667 2.19e-50 174.0 2BKC5@1|root,32ESM@2|Bacteria,4PAIX@976|Bacteroidetes,2FX36@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_549843_1 1038860.AXAP01000015_gene2003 2.43e-40 155.0 COG3740@1|root,COG3740@2|Bacteria,1QVIJ@1224|Proteobacteria,2TVIM@28211|Alphaproteobacteria,3K0XM@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Caudovirus prohead serine protease - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_111745_1 1094466.KQS_08940 5.93e-05 53.5 COG3291@1|root,COG5184@1|root,COG3291@2|Bacteria,COG5184@2|Bacteria,4NDZC@976|Bacteroidetes,1I0G4@117743|Flavobacteriia,2NT7Y@237|Flavobacterium 976|Bacteroidetes M Pkd domain containing protein - - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - CHU_C,He_PIG,fn3 k59_549847_1 1123288.SOV_2c10440 3.7e-77 246.0 COG0553@1|root,COG0553@2|Bacteria,1TP2C@1239|Firmicutes,4H2V4@909932|Negativicutes 909932|Negativicutes KL DEAD-like helicases superfamily - - - - - - - - - - - - N6_N4_Mtase k59_278765_1 329381.D9ICX0_9CAUD 5.28e-16 80.9 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QI82@10662|Myoviridae 10662|Myoviridae S virus tail, fiber - - - - - - - - - - - - - k59_155593_1 186617.M9M8L2_9VIRU 7.13e-33 129.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_489047_1 1234888.K0A2J2_9VIRU 3.95e-09 57.8 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_489047_2 1234888.K0A2J2_9VIRU 5.83e-39 145.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_215558_1 215803.DB30_3022 1.46e-08 64.3 COG1520@1|root,COG3420@1|root,COG4733@1|root,COG1520@2|Bacteria,COG3420@2|Bacteria,COG4733@2|Bacteria,1PEHC@1224|Proteobacteria,437JY@68525|delta/epsilon subdivisions,2X2U0@28221|Deltaproteobacteria,2Z04Z@29|Myxococcales 28221|Deltaproteobacteria P Parallel beta-helix repeats - - - - - - - - - - - - - k59_607806_1 65393.PCC7424_5628 4.05e-25 108.0 COG0358@1|root,COG0467@1|root,COG3378@1|root,COG0358@2|Bacteria,COG0467@2|Bacteria,COG3378@2|Bacteria,1G2WM@1117|Cyanobacteria,3KKMJ@43988|Cyanothece 1117|Cyanobacteria L D5 N terminal like - - - ko:K06919 - - - - ko00000 - - - D5_N,DUF3854,Toprim_N k59_550648_1 1187128.I2GUC6_9CAUD 8.44e-27 108.0 4QBHW@10239|Viruses,4QW8N@35237|dsDNA viruses no RNA stage,4QTT7@28883|Caudovirales,4QJZQ@10662|Myoviridae 10662|Myoviridae S sequence-specific DNA binding transcription factor activity - - - - - - - - - - - - - k59_156019_2 417280.A1YZY4_9CAUD 6.39e-114 353.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QI9F@10662|Myoviridae 10662|Myoviridae S Type III restriction enzyme, res subunit - - - - - - - - - - - - - k59_505050_1 1692249.A0A0K1RLN8_9CIRC 7.71e-16 81.3 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_51628_2 631454.N177_3007 9.1e-50 184.0 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1NKZK@1224|Proteobacteria,2U0EG@28211|Alphaproteobacteria 28211|Alphaproteobacteria S TIGRFAM Phage - - - - - - - - - - - - Terminase_6C k59_51628_3 1505225.A0A068CBG2_9CAUD 1.14e-28 112.0 4QBHW@10239|Viruses,4QTT7@28883|Caudovirales,4QJZQ@10662|Myoviridae 10662|Myoviridae S sequence-specific DNA binding transcription factor activity - - - - - - - - - - - - - k59_99188_1 406818.XBJ1_2043 1.89e-19 94.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,1SMCU@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_570508_1 485913.Krac_8498 3.77e-14 75.5 COG0356@1|root,COG0356@2|Bacteria,2G6NF@200795|Chloroflexi 200795|Chloroflexi C it plays a direct role in the translocation of protons across the membrane atpB - - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A k59_37734_1 1123237.Salmuc_01776 4.82e-11 63.5 COG3750@1|root,COG3750@2|Bacteria,1N77J@1224|Proteobacteria,2UFX6@28211|Alphaproteobacteria 28211|Alphaproteobacteria D Belongs to the UPF0335 family - - - - - - - - - - - - DUF2312 k59_387866_1 1788447.A0A190WHJ9_9CIRC 1.26e-42 154.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_55665_1 521460.Athe_1632 5.43e-14 79.0 COG0741@1|root,COG0741@2|Bacteria,1V6DD@1239|Firmicutes,24JDA@186801|Clostridia,42GU3@68295|Thermoanaerobacterales 186801|Clostridia M PFAM Lytic transglycosylase catalytic yjbJ - - ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 - SLT k59_509421_1 78898.MVEG_04238T0 1.25e-34 138.0 COG0085@1|root,KOG0214@2759|Eukaryota,38F5S@33154|Opisthokonta,3NW78@4751|Fungi,1GS89@112252|Fungi incertae sedis 4751|Fungi K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates RPB2 GO:0000228,GO:0000428,GO:0000775,GO:0000785,GO:0000790,GO:0000792,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005665,GO:0005694,GO:0005720,GO:0005721,GO:0005737,GO:0005739,GO:0006139,GO:0006325,GO:0006342,GO:0006351,GO:0006355,GO:0006366,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010494,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016458,GO:0016591,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030880,GO:0031047,GO:0031048,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031618,GO:0031974,GO:0031981,GO:0032774,GO:0032991,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0040029,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044454,GO:0044464,GO:0045814,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051276,GO:0055029,GO:0060255,GO:0061695,GO:0065007,GO:0070013,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0098687,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1902679,GO:1903506,GO:1903507,GO:1990234,GO:1990904,GO:2000112,GO:2000113,GO:2001141 2.7.7.6 ko:K03010 ko00230,ko00240,ko01100,ko03020,ko05016,ko05169,map00230,map00240,map01100,map03020,map05016,map05169 M00180 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_4,RNA_pol_Rpb2_5,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 k59_283421_1 1296415.JACC01000059_gene1025 7.36e-05 54.7 COG1874@1|root,COG3291@1|root,COG3420@1|root,COG3897@1|root,COG4257@1|root,COG4886@1|root,COG1874@2|Bacteria,COG3291@2|Bacteria,COG3420@2|Bacteria,COG3897@2|Bacteria,COG4257@2|Bacteria,COG4886@2|Bacteria,4NMJ3@976|Bacteroidetes,1IKV6@117743|Flavobacteriia,2YJTU@290174|Aquimarina 976|Bacteroidetes G leucine- rich repeat protein - - - - - - - - - - - - ASH,DUF5011,Laminin_G_3 k59_470452_1 1538804.A0A088FAQ9_9CAUD 1.42e-34 131.0 4QFYS@10239|Viruses,4QUD0@28883|Caudovirales,4QMR9@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_265210_3 1139219.I569_01395 3.78e-16 77.8 2CDFK@1|root,2Z8BH@2|Bacteria,1V43D@1239|Firmicutes,4HY70@91061|Bacilli 91061|Bacilli S DNA N-6-adenine-methyltransferase (Dam) - - - - - - - - - - - - Dam k59_55691_1 573065.Astex_0328 4.59e-20 93.2 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2TTEX@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Terminase - - - - - - - - - - - - Terminase_1 k59_265264_1 1385658.U5KPZ6_9VIRU 3.04e-88 279.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_202443_3 236097.ADG881_1743 5.98e-14 73.9 28HEE@1|root,2Z7QU@2|Bacteria,1MXU6@1224|Proteobacteria,1RZSJ@1236|Gammaproteobacteria,1XNV1@135619|Oceanospirillales 135619|Oceanospirillales S Domain of unknown function (DUF932) - - - - - - - - - - - - DUF932 k59_429058_2 1122201.AUAZ01000017_gene2947 5.21e-114 357.0 COG0749@1|root,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,465DD@72275|Alteromonadaceae 1236|Gammaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity - - - - - - - - - - - - DNA_pol_A k59_431701_2 1379718.S5TMX4_9CIRC 1.87e-39 145.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_616720_2 1380387.JADM01000006_gene1297 4.05e-36 135.0 COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,1RMTU@1236|Gammaproteobacteria,1XH3I@135619|Oceanospirillales 135619|Oceanospirillales M UDP-glucose 4-epimerase - - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd k59_124191_1 1498011.A0A096XUY1_9CAUD 3.29e-12 66.6 4QHBE@10239|Viruses,4QT2W@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_124191_3 1399774.JDWH01000001_gene2887 2.8e-34 131.0 28H9R@1|root,2Z7MD@2|Bacteria,1MVTR@1224|Proteobacteria,1RMPH@1236|Gammaproteobacteria,3X3N1@547|Enterobacter 1236|Gammaproteobacteria S Domain of unknown function (DUF932) - - - - - - - - - - - - DUF932 k59_124191_4 937777.Deipe_0496 1.58e-08 64.7 COG3378@1|root,COG5519@1|root,COG3378@2|Bacteria,COG5519@2|Bacteria 2|Bacteria KL Phage plasmid primase P4 family - - - ko:K02316,ko:K06919 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - D5_N,Pox_D5,Prim-Pol,VirE_N k59_268112_2 1051675.G0YQF1_9CAUD 1.89e-24 106.0 4QW35@35237|dsDNA viruses no RNA stage,4QQ4Q@28883|Caudovirales,4QNNN@10744|Podoviridae 10744|Podoviridae S UvrD-like helicase C-terminal domain - - - - - - - - - - - - - k59_62749_1 1634476.A0A0F6TGK2_9CIRC 5.83e-30 120.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_185928_2 1502851.FG93_01937 1.82e-10 65.9 COG1511@1|root,COG3064@1|root,COG5281@1|root,COG1511@2|Bacteria,COG3064@2|Bacteria,COG5281@2|Bacteria,1QWWI@1224|Proteobacteria,2TX6J@28211|Alphaproteobacteria,3JZ4H@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Prophage tail length tape measure protein - - - - - - - - - - - - TMP_2 k59_431723_1 545264.KB898744_gene2270 3.33e-19 91.3 COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,1RMNP@1236|Gammaproteobacteria,1WWQF@135613|Chromatiales 135613|Chromatiales L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria - - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 k59_534632_1 5671.XP_003392524.1 2.08e-13 76.3 28IEN@1|root,2QTMU@2759|Eukaryota,3XSI5@5653|Kinetoplastida 5653|Kinetoplastida S Poly A polymerase regulatory subunit - - 2.1.1.296 ko:K18776 - - R10812 RC00003,RC00466 ko00000,ko01000,ko03019 - - - PARP_regulatory k59_595932_2 931626.Awo_c30930 4.15e-05 53.9 28K55@1|root,2Z9TX@2|Bacteria,1V0P7@1239|Firmicutes,24DCX@186801|Clostridia,25YTV@186806|Eubacteriaceae 186801|Clostridia S Siphovirus ReqiPepy6 Gp37-like protein - - - - - - - - - - - - Sipho_Gp37 k59_329778_2 240016.ABIZ01000001_gene259 1.13e-31 122.0 COG4760@1|root,COG4760@2|Bacteria,46ZIY@74201|Verrucomicrobia,2IV4T@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Bax inhibitor 1 like - - - - - - - - - - - - BaxI_1 k59_185933_1 105154.Q9MBU0_9VIRU 1.8e-42 151.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_534636_1 470.IX87_01165 5.24e-32 137.0 COG2518@1|root,COG2518@2|Bacteria,1QU6Q@1224|Proteobacteria,1TGQC@1236|Gammaproteobacteria,3NM2S@468|Moraxellaceae 1236|Gammaproteobacteria L DEAD-like helicases superfamily - - - - - - - - - - - - Helicase_C,ResIII k59_124211_1 1517681.HW45_02700 1.16e-14 85.1 COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,1QZAD@1224|Proteobacteria,1RYP3@1236|Gammaproteobacteria 1236|Gammaproteobacteria D nuclear chromosome segregation - - - - - - - - - - - - - k59_349860_3 1131269.AQVV01000013_gene1719 3.18e-07 53.5 COG0381@1|root,COG0381@2|Bacteria 2|Bacteria M UDP-N-acetylglucosamine 2-epimerase activity wecB - 5.1.3.14 ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420 RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 - - - AAA_22,Epimerase_2 k59_391495_1 1618260.A0A0C5I2C5_9CIRC 3.29e-12 70.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_124642_1 1618238.A0A0C5IB41_9CIRC 2.73e-22 101.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_473873_3 7029.ACYPI36509-PA 5.99e-66 222.0 2CTDS@1|root,2S4BN@2759|Eukaryota,39MEW@33154|Opisthokonta,3C42E@33208|Metazoa,3E55M@33213|Bilateria,423CZ@6656|Arthropoda,3SVX3@50557|Insecta,3EDV1@33342|Paraneoptera 2759|Eukaryota S Parvovirus non-structural protein NS1 - - - - - - - - - - - - Parvo_NS1 k59_370745_1 1124991.MU9_2666 1.61e-45 167.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,1RP8Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria K terminase - - - - - - - - - - - - Terminase_1 k59_168425_2 411460.RUMTOR_01348 2.07e-41 151.0 28J3N@1|root,2Z8ZU@2|Bacteria,1V15Z@1239|Firmicutes,249Z0@186801|Clostridia 186801|Clostridia S Phage portal protein - - - - - - - - - - - - Phage_portal k59_87075_1 985867.AEWF01000005_gene2482 1.65e-42 149.0 COG1533@1|root,COG1533@2|Bacteria,1R8E3@1224|Proteobacteria,2U77U@28211|Alphaproteobacteria,47FZA@766|Rickettsiales 766|Rickettsiales L DNA photolyase activity - - 4.1.99.14 ko:K03716 - - - - ko00000,ko01000 - - - - k59_373377_1 545696.HOLDEFILI_01184 5.7e-13 73.9 COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,3VNR9@526524|Erysipelotrichia 526524|Erysipelotrichia L Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - DUF4368,Recombinase,Resolvase,Zn_ribbon_recom k59_169294_2 445971.ANASTE_01705 5.43e-11 66.6 COG0500@1|root,COG2226@2|Bacteria,1TSVN@1239|Firmicutes,24BR1@186801|Clostridia,25XWW@186806|Eubacteriaceae 186801|Clostridia H Mycolic acid cyclopropane synthetase - - - - - - - - - - - - Methyltransf_11,Methyltransf_25,Methyltransf_31 k59_352825_3 1234888.K0A2J2_9VIRU 2.35e-152 450.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_352825_5 1234888.K0A2R8_9VIRU 3.87e-29 120.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_87799_6 5888.CAK63124 1.54e-09 68.6 COG0617@1|root,KOG2159@2759|Eukaryota,3ZBIA@5878|Ciliophora 5878|Ciliophora H Belongs to the tRNA nucleotidyltransferase poly(A) polymerase family - - 2.7.7.72 ko:K00974 ko03013,map03013 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016 - - - PolyA_pol,PolyA_pol_RNAbd k59_642307_1 694427.Palpr_1970 1.81e-28 116.0 COG4675@1|root,COG4675@2|Bacteria 2|Bacteria M tail collar domain protein - - - - - - - - - - - - Collar k59_642307_2 266779.Meso_0240 2.34e-34 131.0 COG4675@1|root,COG4675@2|Bacteria,1Q0KH@1224|Proteobacteria,2UIYI@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Phage Tail Collar Domain - - - - - - - - - - - - Collar k59_148571_1 1519439.JPJG01000060_gene1885 6.03e-09 62.8 COG1783@1|root,COG4373@1|root,COG1783@2|Bacteria,COG4373@2|Bacteria,1TU2Y@1239|Firmicutes,25MM3@186801|Clostridia,2N7J6@216572|Oscillospiraceae 186801|Clostridia S phage Terminase large subunit - - - - - - - - - - - - Terminase_3 k59_292215_3 994479.GL877878_gene3308 4.72e-20 92.0 COG0629@1|root,COG0629@2|Bacteria,2IR4I@201174|Actinobacteria,4ECNJ@85010|Pseudonocardiales 201174|Actinobacteria L ERF superfamily - - - - - - - - - - - - ERF k59_196039_1 756282.M4SPS1_9CAUD 1.14e-44 169.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QM52@10699|Siphoviridae 10699|Siphoviridae S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor - - - - - - - - - - - - - k59_358259_3 306263.Cla_1223 2.51e-15 82.8 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,42M7X@68525|delta/epsilon subdivisions,2YM91@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB GO:0003674,GO:0005488,GO:0005515,GO:0042802 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_155237_1 1049564.TevJSym_ak00940 2.36e-65 215.0 COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,1RMY6@1236|Gammaproteobacteria,1J4D3@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA ilvA GO:0003674,GO:0003824,GO:0004794,GO:0005488,GO:0006082,GO:0006520,GO:0006549,GO:0006566,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009081,GO:0009082,GO:0009097,GO:0009987,GO:0016053,GO:0016597,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0019842,GO:0030170,GO:0031406,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_2699 PALP,Thr_dehydrat_C k59_422557_1 1124780.ANNU01000013_gene3877 3.82e-247 720.0 COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,47NQV@768503|Cytophagia 976|Bacteroidetes F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrd - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_lgC,Ribonuc_red_lgN k59_422557_2 267748.MMOB0340 7.21e-45 162.0 COG0207@1|root,COG0207@2|Bacteria,3WT2X@544448|Tenericutes 544448|Tenericutes F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA - 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt k59_13156_1 324831.LGAS_0896 9.65e-07 57.8 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4HAIF@91061|Bacilli,3F52K@33958|Lactobacillaceae 91061|Bacilli KL domain protein - - - - - - - - - - - - Helicase_C,SNF2_N k59_196841_1 388051.AUFE01000035_gene4020 4.03e-35 133.0 COG4653@1|root,COG4653@2|Bacteria 2|Bacteria G Phage capsid family - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_111417_1 279714.FuraDRAFT_3155 8.87e-17 87.8 28KTY@1|root,2ZAAW@2|Bacteria,1R81A@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_111417_3 1112217.PPL19_05125 7.08e-13 80.1 COG5185@1|root,COG5185@2|Bacteria,1QV8Y@1224|Proteobacteria,1T2AE@1236|Gammaproteobacteria 1236|Gammaproteobacteria D tail protein - - - - - - - - - - - - TMP_2,Tape_meas_lam_C k59_488461_1 1038860.AXAP01000067_gene8427 1.12e-23 104.0 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,2U6BJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S TIGRFAM phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_343728_1 2003327.CAPSD_BPCHP 6.23e-72 244.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_299618_2 12353.Q7Y5C3_BPR69 1.75e-05 50.8 4QBY0@10239|Viruses,4QW35@35237|dsDNA viruses no RNA stage,4QQ4Q@28883|Caudovirales,4QIYE@10662|Myoviridae 10662|Myoviridae S AAA domain - - - - - - - - - - - - - k59_586388_4 929562.Emtol_1428 7.39e-07 55.8 COG1403@1|root,COG1403@2|Bacteria,4NJ0T@976|Bacteroidetes,47MEF@768503|Cytophagia 976|Bacteroidetes L HNH endonuclease - - - - - - - - - - - - HNH,HNH_5 k59_266408_1 1121382.JQKG01000001_gene2497 4.09e-19 90.1 COG0210@1|root,COG0210@2|Bacteria,1WN9U@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus L UvrD-like helicase C-terminal domain - - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k59_117882_1 1322246.BN4_20101 7.65e-19 93.6 COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,42QJ2@68525|delta/epsilon subdivisions,2WM78@28221|Deltaproteobacteria,2M8CT@213115|Desulfovibrionales 28221|Deltaproteobacteria S VWA-like domain (DUF2201) - - - - - - - - - - - - DUF2201,DUF2201_N k59_284495_1 1618251.A0A0C5I2L8_9CIRC 1.36e-25 106.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_471591_1 1336241.JAEB01000012_gene1784 5.22e-13 74.3 COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia,25V2F@186806|Eubacteriaceae 186801|Clostridia M Penicillin-binding protein, transpeptidase domain protein - - - ko:K08384 ko00550,map00550 - - - ko00000,ko00001,ko01011 - - - PBP_dimer,Transpeptidase k59_305850_1 864702.OsccyDRAFT_3629 1.32e-05 53.5 COG5545@1|root,COG5545@2|Bacteria,1G1ZC@1117|Cyanobacteria,1HATX@1150|Oscillatoriales 1117|Cyanobacteria S Virulence-associated protein E - - - - - - - - - - - - DUF3854,Prim-Pol,VirE k59_117910_1 1538804.A0A088F6T3_9CAUD 3.76e-27 114.0 4QAKM@10239|Viruses,4QPEF@28883|Caudovirales,4QKNE@10699|Siphoviridae 10699|Siphoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_266451_2 323261.Noc_0053 1.13e-111 341.0 COG0305@1|root,COG0305@2|Bacteria,1QWI1@1224|Proteobacteria,1RZ7K@1236|Gammaproteobacteria,1X1UJ@135613|Chromatiales 135613|Chromatiales L Toprim-like - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - DnaB_C k59_510441_2 397290.C810_01502 2e-14 72.0 2EDYB@1|root,337T6@2|Bacteria,1VMZH@1239|Firmicutes,24VTA@186801|Clostridia,27S7W@186928|unclassified Lachnospiraceae 186801|Clostridia - - - - - - - - - - - - - - - k59_510441_3 1313421.JHBV01000031_gene1416 3.77e-111 328.0 COG0860@1|root,COG3409@1|root,COG0860@2|Bacteria,COG3409@2|Bacteria 2|Bacteria M Peptidoglycan-binding domain 1 protein - - 3.5.1.28,3.5.2.6 ko:K01448,ko:K02172,ko:K06381,ko:K17836 ko00311,ko01130,ko01501,ko01503,map00311,map01130,map01501,map01503 M00627,M00628,M00727 R04112,R06363 RC00064,RC00141,RC01499 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko03036 - - - Amidase_3,Beta-lactamase2,Glucosaminidase,LysM,PG_binding_1,Peptidase_M56,SpoIID,Y_Y_Y k59_39049_1 1234888.K0A2J2_9VIRU 8.36e-76 245.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_511396_1 2711.XP_006485769.1 1.24e-36 136.0 COG0193@1|root,KOG2255@2759|Eukaryota,37HFV@33090|Viridiplantae,3G8N9@35493|Streptophyta 35493|Streptophyta J Belongs to the PTH family - GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0016787,GO:0016788,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro k59_244203_1 1122981.AUME01000026_gene524 6.76e-14 76.6 COG5280@1|root,COG5280@2|Bacteria,4PNYN@976|Bacteroidetes,2FPMT@200643|Bacteroidia 976|Bacteroidetes S domain protein - - - - - - - - - - - - - k59_409208_1 1392498.JQLH01000001_gene3059 2.92e-20 103.0 COG3210@1|root,COG3210@2|Bacteria,4PKI0@976|Bacteroidetes,1IKUE@117743|Flavobacteriia,2PI31@252356|Maribacter 976|Bacteroidetes U PFAM Collagen triple helix repeat (20 copies) - - - - - - - - - - - - - k59_432109_3 1235689.K4NWL6_9CAUD 9e-42 160.0 4QAY9@10239|Viruses,4QWGZ@35237|dsDNA viruses no RNA stage,4QRJC@28883|Caudovirales,4QP2W@10744|Podoviridae 10744|Podoviridae S DNA primase activity - - - - - - - - - - - - - k59_555370_4 647113.Metok_1356 5.96e-09 69.7 COG5306@1|root,arCOG03508@2157|Archaea,arCOG06599@2157|Archaea,2XWAH@28890|Euryarchaeota,23QAG@183939|Methanococci 183939|Methanococci S Domain of unknown function (DUF2341) - - - - - - - - - - - - DUF2341 k59_288576_7 1285586.H131_22204 3.68e-09 54.3 29R18@1|root,30C2C@2|Bacteria,1W3U4@1239|Firmicutes,4I259@91061|Bacilli,3IYYN@400634|Lysinibacillus 91061|Bacilli - - - - - - - - - - - - - - - k59_617502_1 889378.Spiaf_2417 5.75e-15 80.9 COG0209@1|root,COG0209@2|Bacteria 2|Bacteria F ribonucleoside-diphosphate reductase activity rtpR - 1.1.98.6,1.17.4.1 ko:K00525,ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024,R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,LAGLIDADG_3,Ribonuc_red_lgC k59_42609_1 1229276.DI53_1323 1.83e-48 159.0 COG0720@1|root,COG0720@2|Bacteria,4NM8H@976|Bacteroidetes 976|Bacteroidetes H 6-pyruvoyl tetrahydropterin synthase queD - 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 - - - PTPS k59_42609_2 536232.CLM_1798 1.19e-53 178.0 COG0603@1|root,COG0603@2|Bacteria,1TP4Z@1239|Firmicutes,2497A@186801|Clostridia,36DMD@31979|Clostridiaceae 186801|Clostridia F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) queC - 6.3.4.20 ko:K06920 ko00790,ko01100,map00790,map01100 - R09978 RC00959 ko00000,ko00001,ko01000,ko03016 - - - QueC k59_227259_1 1609634.A0A0C5AFV4_9VIRU 6.5e-46 171.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_2090_2 1121403.AUCV01000013_gene3930 9e-06 48.5 COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,42MKY@68525|delta/epsilon subdivisions,2WM9K@28221|Deltaproteobacteria,2MKHH@213118|Desulfobacterales 28221|Deltaproteobacteria E Pyridoxal-phosphate dependent enzyme ilvA - 4.3.1.17,4.3.1.19 ko:K01754,ko:K17989 ko00260,ko00270,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00590,R00996 RC00331,RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - ACT,PALP,Thr_dehydrat_C k59_63371_1 572265.HDEF_0629 2.04e-67 230.0 COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RMTB@1236|Gammaproteobacteria,282PB@191675|unclassified Enterobacteriaceae 1236|Gammaproteobacteria O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009987,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019058,GO:0019068,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0044183,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0097159,GO:0097367,GO:0101031,GO:1901265,GO:1901363,GO:1990220 - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 k59_535449_1 1121289.JHVL01000007_gene2775 6.56e-40 162.0 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,2487V@186801|Clostridia,36EDD@31979|Clostridiaceae 186801|Clostridia L DNA polymerase - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_535449_3 679197.HMPREF9336_02239 1.82e-06 50.8 2EI48@1|root,33BVK@2|Bacteria,2GZ85@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_535449_6 388401.RB2150_15970 3.52e-08 64.7 COG3378@1|root,COG3378@2|Bacteria,1MV7I@1224|Proteobacteria,2TRS2@28211|Alphaproteobacteria,3ZIK7@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria S D5 N terminal like - - - ko:K06919 - - - - ko00000 - - - D5_N,Pox_D5 k59_535449_19 1432055.GLUCORHAEAF1_16365 0.000445 43.1 2EMWV@1|root,33FJ4@2|Bacteria,1NI97@1224|Proteobacteria,2UJMC@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_272319_1 716544.wcw_0485 1.39e-61 203.0 COG0109@1|root,COG0109@2|Bacteria,2JFWP@204428|Chlamydiae 204428|Chlamydiae H Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group cyoE - 2.5.1.141 ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 M00154 R07411 RC01786 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 - - - UbiA k59_293238_1 1353529.M899_2696 0.000516 50.8 COG3250@1|root,COG5295@1|root,COG3250@2|Bacteria,COG5295@2|Bacteria 2|Bacteria UW Hep Hag repeat protein - - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - ESPR,Peptidase_S74,YadA_anchor,YadA_head,YadA_stalk k59_45876_2 547045.NEISICOT_01693 4.48e-23 107.0 COG0714@1|root,COG0714@2|Bacteria,1PM35@1224|Proteobacteria,2VM64@28216|Betaproteobacteria,2KRK7@206351|Neisseriales 206351|Neisseriales S AAA domain (dynein-related subfamily) - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_5 k59_498235_2 1088721.NSU_pLA2074 2.3e-06 48.1 2AKKP@1|root,31BD1@2|Bacteria,1NYYR@1224|Proteobacteria,2UT2T@28211|Alphaproteobacteria,2KAYI@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - k59_252412_1 1609634.A0A0C5AFV4_9VIRU 4.55e-100 313.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_579876_2 691965.D4P7B9_9CAUD 2.07e-24 96.7 4QFDH@10239|Viruses,4QWV5@35237|dsDNA viruses no RNA stage,4QPB8@28883|Caudovirales,4QKNN@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_520208_1 1123312.KB904575_gene72 1.43e-60 206.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4H9YP@91061|Bacilli 91061|Bacilli L SNF2 family - - - - - - - - - - - - Helicase_C,SNF2_N k59_520208_2 985762.SAGN_06040 3.39e-16 75.9 COG1403@1|root,COG1403@2|Bacteria,1VA8J@1239|Firmicutes,4HNCA@91061|Bacilli,4GZVD@90964|Staphylococcaceae 91061|Bacilli L COG1403 Restriction endonuclease - - - ko:K07451 - - - - ko00000,ko01000,ko02048 - - - HNH k59_520208_4 940282.CADQ01000042_gene690 1.41e-164 487.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2TSDW@28211|Alphaproteobacteria,2JYGZ@204441|Rhodospirillales 204441|Rhodospirillales S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_540607_2 1380354.JIAN01000005_gene1679 1.73e-06 48.1 2E39Y@1|root,32Y9G@2|Bacteria,2GQJA@201174|Actinobacteria,4F1MN@85016|Cellulomonadaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_438394_1 1406780.U5PZU8_9CAUD 2.05e-17 87.0 4QBMV@10239|Viruses,4QUU6@35237|dsDNA viruses no RNA stage,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_644161_1 1618256.A0A0C5IM93_9CIRC 1.19e-16 82.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_89371_1 861208.AGROH133_06202 3.56e-108 340.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2TSDW@28211|Alphaproteobacteria,4BCQ8@82115|Rhizobiaceae 28211|Alphaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_26482_2 1203605.HMPREF1531_01727 0.00015 45.1 2CC1Y@1|root,32RUK@2|Bacteria,2IQ4Q@201174|Actinobacteria,4DRN7@85009|Propionibacteriales 201174|Actinobacteria K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA whiB2 - - ko:K18955 - - - - ko00000,ko03000 - - - Whib k59_194989_2 1045856.EcWSU1_02967 9.24e-05 52.4 COG0438@1|root,COG0438@2|Bacteria,1MVKK@1224|Proteobacteria,1RQ8J@1236|Gammaproteobacteria,3X0GR@547|Enterobacter 1236|Gammaproteobacteria M PFAM Glycosyl transferase, group 1 wcaL GO:0003674,GO:0003824,GO:0016740,GO:0016757 - ko:K16703 - - - - ko00000,ko01000,ko01003 - GT4 - Glyco_transf_4,Glycos_transf_1 k59_194989_3 384616.Pisl_1491 8.97e-05 51.6 COG0500@1|root,arCOG01400@2157|Archaea 2157|Archaea Q TIGRFAM methyltransferase FkbM family - - - - - - - - - - - - Methyltransf_21 k59_485843_2 579138.Zymop_1663 7.34e-06 53.1 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2TQZE@28211|Alphaproteobacteria,2K148@204457|Sphingomonadales 204457|Sphingomonadales M COG0739 Membrane proteins related to metalloendopeptidases - - - - - - - - - - - - Peptidase_M23 k59_95054_1 1141106.CAIB01000118_gene968 1.49e-09 61.2 COG3935@1|root,COG3935@2|Bacteria,1VHK1@1239|Firmicutes,4I46Z@91061|Bacilli,4H03Q@90964|Staphylococcaceae 91061|Bacilli L Helix-turn-helix domain - - - - - - - - - - - - DnaB_2,HTH_36 k59_316875_1 1116472.MGMO_218c00030 5.59e-81 249.0 COG1609@1|root,COG1609@2|Bacteria,1MVZ4@1224|Proteobacteria,1RMGU@1236|Gammaproteobacteria 1236|Gammaproteobacteria K binds specific sites in lac operon resulting in DNA looping between the operators lacI GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042802,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - - - - - - - - - - LacI,Peripla_BP_3 k59_546608_1 1234888.K0A2J2_9VIRU 4.07e-36 137.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_276501_2 1073754.G0ZNE5_9VIRU 1.5e-41 144.0 4QAIU@10239|Viruses 10239|Viruses S HNH endonuclease - - - - - - - - - - - - - k59_276501_3 1095747.HMPREF1049_1056 5.14e-11 65.9 COG0208@1|root,COG0208@2|Bacteria,378I2@32066|Fusobacteria 32066|Fusobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides - - 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_sm k59_502329_1 1177594.MIC448_1190014 2.08e-26 104.0 COG0545@1|root,COG0545@2|Bacteria,2IHQC@201174|Actinobacteria,4FP5U@85023|Microbacteriaceae 201174|Actinobacteria O FKBP-type peptidyl-prolyl cis-trans isomerase fkbP - 5.2.1.8 ko:K01802,ko:K03772 - - - - ko00000,ko01000,ko03110 - - - FKBP_C k59_195017_1 485913.Krac_4688 1.31e-33 125.0 COG1437@1|root,COG1437@2|Bacteria,2G9FW@200795|Chloroflexi 200795|Chloroflexi F CYTH domain - - 4.6.1.1 ko:K05873 ko00230,map00230 - R00089,R00434 RC00295 ko00000,ko00001,ko01000 - - - CYTH k59_526322_2 1150599.MPHLEI_22419 2.83e-50 168.0 2EB9A@1|root,3359T@2|Bacteria,2INFV@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_526322_3 1121445.ATUZ01000017_gene2107 1.37e-05 51.2 COG1738@1|root,COG1738@2|Bacteria,1N0RB@1224|Proteobacteria,4329A@68525|delta/epsilon subdivisions,2WY3W@28221|Deltaproteobacteria,2MB9S@213115|Desulfovibrionales 28221|Deltaproteobacteria S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage - - - ko:K09125 - - - - ko00000 - - - Vut_1 k59_11076_3 145579.REP_BPPHM 2.58e-32 129.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_11076_5 1385658.U5KPZ6_9VIRU 6.34e-184 530.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_153578_1 202956.BBNL01000060_gene1856 5.46e-28 114.0 COG0270@1|root,COG0270@2|Bacteria,1MV9H@1224|Proteobacteria,1RPM4@1236|Gammaproteobacteria,3NPF7@468|Moraxellaceae 1236|Gammaproteobacteria L C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_30503_1 387093.SUN_0712 1.29e-15 82.4 COG1253@1|root,COG1253@2|Bacteria,1MWT3@1224|Proteobacteria,42N45@68525|delta/epsilon subdivisions,2YTP5@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria S Domain of unknown function DUF21 - - - - - - - - - - - - CBS,DUF21 k59_502357_1 1618248.A0A0C5IB82_9CIRC 1.28e-11 65.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_199993_3 1538644.KO02_12365 8.9e-31 120.0 2DXNB@1|root,345PI@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_181545_2 1537917.JU82_06570 3.27e-54 176.0 2CGG9@1|root,2ZVSJ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_347660_1 369723.Strop_1948 1.15e-41 155.0 COG4676@1|root,COG4676@2|Bacteria,2GPA6@201174|Actinobacteria,4DCBY@85008|Micromonosporales 201174|Actinobacteria S Protein conserved in bacteria - - - - - - - - - - - - - k59_102004_1 105154.Q9MBU3_9VIRU 8.76e-13 71.6 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_302641_1 1123229.AUBC01000015_gene4684 7.14e-09 63.2 COG1196@1|root,COG3941@1|root,COG1196@2|Bacteria,COG3941@2|Bacteria,1RM55@1224|Proteobacteria,2U759@28211|Alphaproteobacteria 28211|Alphaproteobacteria D Prophage tail length tape measure protein - - - - - - - - - - - - TMP_2,Tape_meas_lam_C k59_589408_1 1476390.A0A060RFG9_9CAUD 7.16e-20 92.0 4QBA5@10239|Viruses,4QXFW@35237|dsDNA viruses no RNA stage,4QPTU@28883|Caudovirales,4QN4A@10699|Siphoviridae 10699|Siphoviridae S AAA domain - - - - - - - - - - - - - k59_35471_1 309798.COPRO5265_0219 3.66e-14 73.2 COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,42EKM@68295|Thermoanaerobacterales 186801|Clostridia C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family trxB - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Thioredoxin_3 k59_262631_1 1123504.JQKD01000021_gene5682 5.84e-86 274.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2VNHP@28216|Betaproteobacteria,4AC68@80864|Comamonadaceae 28216|Betaproteobacteria S Terminase - - - - - - - - - - - - Terminase_1 k59_610110_1 742727.HMPREF9447_04874 1.26e-64 206.0 COG0863@1|root,COG0863@2|Bacteria,4NQQ1@976|Bacteroidetes,2G1PS@200643|Bacteroidia,4ARBB@815|Bacteroidaceae 976|Bacteroidetes L DNA methylase - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_631419_1 1609634.A0A0C5AFV4_9VIRU 4.43e-26 107.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_631419_2 1609634.A0A0C5AFV4_9VIRU 1.07e-06 53.5 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_568328_1 269482.Bcep1808_4568 8.82e-37 136.0 COG2963@1|root,COG2963@2|Bacteria 2|Bacteria L transposase activity - - - ko:K07483,ko:K07497 - - - - ko00000 - - - HTH_Tnp_1,HTH_Tnp_IS630 k59_610126_1 1223410.KN050846_gene1233 2.24e-06 52.4 2ECBS@1|root,336A4@2|Bacteria,4PMF6@976|Bacteroidetes,1IJRW@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_217287_1 1358423.N180_03800 2.65e-09 57.0 COG4122@1|root,COG4122@2|Bacteria,4NQW7@976|Bacteroidetes,1IXC9@117747|Sphingobacteriia 976|Bacteroidetes S O-methyltransferase activity - - - - - - - - - - - - Methyltransf_24 k59_347741_2 1537917.JU82_09980 1.33e-28 107.0 2ARVA@1|root,31H70@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - HK97-gp10_like k59_200803_1 1121367.AQXC01000001_gene1467 1.59e-11 71.6 COG1061@1|root,COG1061@2|Bacteria,2GIU5@201174|Actinobacteria,22JJC@1653|Corynebacteriaceae 201174|Actinobacteria L DNA or RNA helicases of superfamily II sdrA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - ResIII k59_115267_1 1234888.K0A2J2_9VIRU 1.5e-90 285.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_217855_1 424716.B1GS49_9CAUD 2.83e-35 142.0 4QHQR@10239|Viruses,4QV7H@35237|dsDNA viruses no RNA stage,4QSV7@28883|Caudovirales,4QKSI@10699|Siphoviridae 10699|Siphoviridae S DNA binding - - - - - - - - - - - - - k59_303429_1 266779.Meso_1200 1.81e-67 216.0 COG0863@1|root,COG0863@2|Bacteria,1NQ2A@1224|Proteobacteria,2UJ12@28211|Alphaproteobacteria,43KMC@69277|Phyllobacteriaceae 28211|Alphaproteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - - - - - - - - - - - N6_N4_Mtase k59_426832_1 1313265.JNIE01000003_gene1143 1.16e-22 94.4 COG0756@1|root,COG0756@2|Bacteria,2G4CU@200783|Aquificae 200783|Aquificae F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA dut GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase k59_636509_1 1618260.A0A0C5I2C5_9CIRC 2.05e-33 126.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_164881_1 439375.Oant_0254 8.41e-55 180.0 2CWXD@1|root,32T0J@2|Bacteria,1N3Z7@1224|Proteobacteria,2UMWB@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_390713_1 1169152.AXVD01000037_gene2959 3.24e-07 60.1 COG0791@1|root,COG1511@1|root,COG0791@2|Bacteria,COG1511@2|Bacteria 2|Bacteria Q domain protein MA20_07280 - - ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4 - - GAF_2,HAMP,HATPase_c,HisKA,Response_reg k59_616379_1 1510531.JQJJ01000009_gene989 3.64e-10 64.7 COG5281@1|root,COG5281@2|Bacteria,1R47M@1224|Proteobacteria,2TUIV@28211|Alphaproteobacteria,3JY6I@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S COG5281, Phage-related minor tail protein - - - - - - - - - - - - - k59_595616_5 1026955.F5B475_9CAUD 1.44e-16 80.1 4QAKE@10239|Viruses,4QUP7@35237|dsDNA viruses no RNA stage,4QPCE@28883|Caudovirales,4QI56@10662|Myoviridae 10662|Myoviridae S nucleic acid binding - - - - - - - - - - - - - k59_185589_4 1123311.KB904448_gene55 6.07e-23 101.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4H9YP@91061|Bacilli 91061|Bacilli L SNF2 family - - - - - - - - - - - - Helicase_C,SNF2_N k59_431404_1 1234888.K0A2J2_9VIRU 2.85e-51 187.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_205558_2 1449069.JMLO01000001_gene1579 2.7e-09 57.0 2CICW@1|root,346YY@2|Bacteria,2HIJU@201174|Actinobacteria,4G48K@85025|Nocardiaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_83201_1 313596.RB2501_02025 1.32e-05 57.0 COG3210@1|root,COG3210@2|Bacteria,4PKI0@976|Bacteroidetes,1HYWF@117743|Flavobacteriia 976|Bacteroidetes U PFAM Collagen triple helix repeat (20 copies) - - - - - - - - - - - - Collagen k59_392481_1 272560.BPSL1143 1.36e-63 217.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2VNHP@28216|Betaproteobacteria,1K7BW@119060|Burkholderiaceae 28216|Betaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_43431_1 1618257.A0A0C5IBI9_9CIRC 2.27e-31 122.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_371784_3 1676184.A0A186YBN5_9CIRC 5.48e-40 152.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_125817_2 1618236.A0A0C5IB23_9CIRC 3.39e-26 110.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_3122_1 1144319.PMI16_03070 1.96e-11 66.6 COG3409@1|root,COG3409@2|Bacteria,1R4RS@1224|Proteobacteria,2VTC5@28216|Betaproteobacteria 28216|Betaproteobacteria M CHAP domain - - - - - - - - - - - - CHAP k59_433511_1 1161401.ASJA01000008_gene1673 9.29e-05 53.9 COG1196@1|root,COG5281@1|root,COG1196@2|Bacteria,COG5281@2|Bacteria,1MX2R@1224|Proteobacteria,2U3WK@28211|Alphaproteobacteria 28211|Alphaproteobacteria D tape measure protein - - - - - - - - - - - - Peptidase_M15_4,Tape_meas_lam_C k59_207157_1 388051.AUFE01000035_gene4020 2.98e-39 143.0 COG4653@1|root,COG4653@2|Bacteria 2|Bacteria G Phage capsid family - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_85224_1 1385658.U5KPZ6_9VIRU 8.21e-31 123.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_639405_6 1316932.MHH_c11630 1.31e-05 54.7 28H88@1|root,2Z7K7@2|Bacteria,1R5AY@1224|Proteobacteria,1RZB1@1236|Gammaproteobacteria,1Y86Y@135625|Pasteurellales 135625|Pasteurellales - - - - - - - - - - - - - - Phage_cap_E k59_639405_14 68219.JNXI01000001_gene6110 8.23e-08 55.8 2BTCI@1|root,32NIA@2|Bacteria,2IC2R@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_639405_15 1121022.ABENE_12120 1.32e-05 58.9 COG0739@1|root,COG0739@2|Bacteria,1R8E7@1224|Proteobacteria,2TYFZ@28211|Alphaproteobacteria,2KKAG@204458|Caulobacterales 204458|Caulobacterales M BlaR1 peptidase M56 - - - - - - - - - - - - Peptidase_M23,Peptidase_M56 k59_475523_1 1463934.JOCF01000064_gene4216 1.08e-48 166.0 COG0270@1|root,COG0270@2|Bacteria,2GNB2@201174|Actinobacteria 201174|Actinobacteria L DNA (cytosine-5-)-methyltransferase activity - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_392689_1 477641.MODMU_1705 1.15e-22 105.0 COG0286@1|root,COG1111@1|root,COG4889@1|root,COG0286@2|Bacteria,COG1111@2|Bacteria,COG4889@2|Bacteria,2GJEP@201174|Actinobacteria,4EWCJ@85013|Frankiales 201174|Actinobacteria L site-specific DNA-methyltransferase (adenine-specific) activity - - - - - - - - - - - - N6_Mtase k59_392697_1 1244869.H261_10527 2.99e-13 69.7 2EIAE@1|root,30RJN@2|Bacteria,1P0MA@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_354196_1 926692.AZYG01000082_gene546 8.39e-71 238.0 COG2268@1|root,COG2268@2|Bacteria 2|Bacteria T Band 7 protein - - - ko:K07192 ko04910,map04910 - - - ko00000,ko00001,ko03036,ko04131,ko04147 - - - Band_7,DUF4157,Flot,Mob_Pre k59_149999_1 929556.Solca_3424 7.14e-28 125.0 COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,4NIIR@976|Bacteroidetes,1IPF7@117747|Sphingobacteriia 976|Bacteroidetes L Belongs to the helicase family. UvrD subfamily - - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C k59_498753_2 186617.M9M8L2_9VIRU 7.2e-28 119.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_210101_1 940282.CADQ01000042_gene690 8.25e-45 162.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2TSDW@28211|Alphaproteobacteria,2JYGZ@204441|Rhodospirillales 204441|Rhodospirillales S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_336265_1 1050201.KB913034_gene999 4.72e-21 99.4 COG3757@1|root,COG3757@2|Bacteria,1UWPN@1239|Firmicutes,3VRZ5@526524|Erysipelotrichia 2|Bacteria M hydrolase, family 25 - - - - - - - - - - - - Glyco_hydro_25 k59_7152_2 1000565.METUNv1_03721 5.2e-05 51.2 COG2946@1|root,COG2946@2|Bacteria,1RDKM@1224|Proteobacteria,2VNHY@28216|Betaproteobacteria,2KX1X@206389|Rhodocyclales 206389|Rhodocyclales L Replication initiation factor - - - - - - - - - - - - Rep_trans k59_375798_4 1408418.JNJH01000043_gene3127 1.37e-73 234.0 2FITE@1|root,34AIX@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_46335_1 272134.KB731324_gene5410 8.48e-16 79.0 2CWYZ@1|root,32T0P@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_644538_1 1692254.A0A0K1RLS2_9CIRC 2.61e-19 92.8 4QB6C@10239|Viruses,4QUKM@29258|ssDNA viruses 10239|Viruses J Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_171400_1 1395516.PMO01_03075 3.8e-34 127.0 2DP75@1|root,330U8@2|Bacteria,1N8XA@1224|Proteobacteria,1SCZN@1236|Gammaproteobacteria 1236|Gammaproteobacteria S HNH endonuclease - - - - - - - - - - - - AP2,HNH_3 k59_458460_1 1163409.UUA_14809 2.24e-15 80.1 COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,1RMCS@1236|Gammaproteobacteria,1X2XX@135614|Xanthomonadales 135614|Xanthomonadales E Belongs to the DegT DnrJ EryC1 family - - - - - - - - - - - - DegT_DnrJ_EryC1 k59_89759_1 1379725.S5TMY9_9CIRC 7.24e-30 125.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_580663_2 158189.SpiBuddy_0286 8.69e-19 95.5 COG5519@1|root,COG5519@2|Bacteria 2|Bacteria - - - - - ko:K06919 - - - - ko00000 - - - DUF927,zf-CHC2 k59_498782_1 426114.THI_1948 1.11e-44 164.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2VNHP@28216|Betaproteobacteria 28216|Betaproteobacteria S Terminase - - - - - - - - - - - - Terminase_1 k59_416851_1 638303.Thal_1246 9.99e-09 65.9 COG0749@1|root,COG0749@2|Bacteria,2G4NU@200783|Aquificae 200783|Aquificae L DNA polymerase polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - DNA_pol_A,DNA_pol_A_exo1 k59_541484_1 1636270.A0A0E3JPE0_9CAUD 1.01e-05 50.1 4QBI1@10239|Viruses,4QPC5@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_313492_1 942016.E9NII1_9CAUD 1.1e-06 55.8 4QGGR@10239|Viruses,4QZHR@35237|dsDNA viruses no RNA stage,4QUGZ@28883|Caudovirales,4QNY3@10744|Podoviridae 10744|Podoviridae S viral capsid - - - - - - - - - - - - - k59_541910_1 1380894.S5TR92_9CIRC 3.12e-16 84.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_645112_1 1609634.A0A0C5ANA6_9VIRU 9.16e-11 67.0 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_10823_1 1618248.A0A0C5IB82_9CIRC 8.05e-19 84.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_10823_2 1692242.A0A0K1RKZ2_9CIRC 7.1e-43 155.0 4QFEW@10239|Viruses,4QUKZ@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_10823_3 1692257.A0A0K1RL39_9CIRC 1.38e-64 210.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_626050_1 1379713.S5SYD9_9CIRC 5.86e-06 51.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_563604_1 768671.ThimaDRAFT_2798 2.98e-06 54.7 COG0582@1|root,COG0582@2|Bacteria 2|Bacteria L DNA integration - - - - - - - - - - - - PHINT_rpt,Phage_Integr_2,Phage_int_SAM_1,Phage_integrase k59_564032_5 1151122.AQYD01000006_gene1759 2.48e-06 56.2 COG4733@1|root,COG4733@2|Bacteria,2GMKC@201174|Actinobacteria,4FKWD@85023|Microbacteriaceae 201174|Actinobacteria S Fibronectin type 3 domain - - - - - - - - - - - - - k59_297986_2 620914.JH621284_gene1588 1.05e-10 61.2 COG3108@1|root,COG3108@2|Bacteria,4NR2G@976|Bacteroidetes,1I3PE@117743|Flavobacteriia,2YM3D@290174|Aquimarina 2|Bacteria S Peptidase M15 - - - - - - - - - - - - Peptidase_M15_3 k59_95490_2 1609634.A0A0C5AFV4_9VIRU 2.72e-71 232.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_213425_1 1120936.KB907208_gene1116 1.32e-26 109.0 2FA48@1|root,342D2@2|Bacteria,2H6VX@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_49809_2 71421.HI_0765 0.000291 49.7 COG3306@1|root,COG3306@2|Bacteria,1RI6Z@1224|Proteobacteria,1SYHZ@1236|Gammaproteobacteria,1Y9W1@135625|Pasteurellales 135625|Pasteurellales M Lipooligosaccharide biosynthesis protein - - - ko:K07270 - - - - ko00000 - GT25 - Glyco_transf_25 k59_462664_1 870187.Thini_0411 1.51e-21 98.2 2EP1Y@1|root,33GNT@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_486198_1 1027292.HMPREF9372_0586 6.51e-05 52.0 COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,4H9WA@91061|Bacilli,26DRP@186818|Planococcaceae 91061|Bacilli D Belongs to the FtsK SpoIIIE SftA family ftsK GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma k59_486198_2 762966.HMPREF9439_00997 1.58e-35 137.0 COG3723@1|root,COG3723@2|Bacteria,1R6DB@1224|Proteobacteria,2W11U@28216|Betaproteobacteria,4PRPY@995019|Sutterellaceae 28216|Betaproteobacteria L RecT family - - - - - - - - - - - - RecT k59_110145_1 1540097.A0A0A0YRN0_9CAUD 1.61e-92 293.0 4QF3C@10239|Viruses,4QU4U@28883|Caudovirales,4QNNQ@10744|Podoviridae 10744|Podoviridae S host cell wall - - - - - - - - - - - - - k59_195239_1 794903.OPIT5_08140 1.88e-24 98.6 COG0270@1|root,COG0270@2|Bacteria 2|Bacteria L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_588656_2 472175.EL18_01353 3.75e-11 67.0 COG3772@1|root,COG3772@2|Bacteria,1N3ZC@1224|Proteobacteria 1224|Proteobacteria S lysozyme - - - - - - - - - - - - - k59_655816_1 1611039.A0A0C5C3Z3_9CIRC 1.72e-07 53.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_655816_3 1379695.S5TNA9_9CIRC 6.57e-49 170.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_261678_2 686340.Metal_2604 3.09e-10 61.6 2ERQK@1|root,33J9W@2|Bacteria,1NQEB@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_425111_1 403833.Pmob_0798 1.96e-25 104.0 COG1403@1|root,COG1403@2|Bacteria,2GDSZ@200918|Thermotogae 200918|Thermotogae L HNH endonuclease - - - - - - - - - - - - RRXRR k59_360798_1 1692249.A0A0K1RLN8_9CIRC 7.23e-27 109.0 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_321329_2 1121286.AUMT01000002_gene1393 1.47e-08 53.9 COG0629@1|root,COG0629@2|Bacteria,4NT9M@976|Bacteroidetes,1I1XK@117743|Flavobacteriia,3ZRV0@59732|Chryseobacterium 976|Bacteroidetes L Domain of unknown function (DUF3127) - - - - - - - - - - - - DUF3127 k59_630636_4 89187.ISM_05190 1.59e-16 87.0 COG5281@1|root,COG5281@2|Bacteria,1R47M@1224|Proteobacteria,2TUIV@28211|Alphaproteobacteria,46QA2@74030|Roseovarius 28211|Alphaproteobacteria S COG5281 Phage-related minor tail protein - - - - - - - - - - - - - k59_467217_1 1218352.B597_019440 6.22e-19 81.3 COG4570@1|root,COG4570@2|Bacteria,1N92D@1224|Proteobacteria,1TA3B@1236|Gammaproteobacteria,1Z47G@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria L Endodeoxyribonuclease RusA - - - - - - - - - - - - RusA k59_449290_2 397290.C810_01484 2.71e-53 178.0 2CWXD@1|root,32T0J@2|Bacteria,1VCVP@1239|Firmicutes,24MPK@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_199669_2 1286619.L7WUM1_9CIRC 4.67e-20 90.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_119328_1 942016.E9NIH0_9CAUD 3.3e-35 137.0 4QGA5@10239|Viruses,4QURD@35237|dsDNA viruses no RNA stage,4QT9N@28883|Caudovirales,4QP47@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_573780_2 445974.CLORAM_02950 1.26e-26 108.0 2DPVC@1|root,333IQ@2|Bacteria,1UKHD@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - k59_222070_1 51511.ENSCSAVP00000011276 1.85e-15 83.2 COG0187@1|root,KOG0355@2759|Eukaryota,38CPA@33154|Opisthokonta,3BFVW@33208|Metazoa,3CW22@33213|Bilateria,4871R@7711|Chordata 33208|Metazoa B DNA topoisomerase II activity TOP2B GO:0000003,GO:0000070,GO:0000075,GO:0000166,GO:0000182,GO:0000217,GO:0000228,GO:0000278,GO:0000280,GO:0000287,GO:0000302,GO:0000400,GO:0000712,GO:0000785,GO:0000790,GO:0000792,GO:0000793,GO:0000819,GO:0000902,GO:0000904,GO:0001764,GO:0002244,GO:0002376,GO:0002520,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003690,GO:0003696,GO:0003723,GO:0003729,GO:0003824,GO:0003916,GO:0003918,GO:0005080,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005730,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006265,GO:0006266,GO:0006282,GO:0006310,GO:0006323,GO:0006325,GO:0006342,GO:0006355,GO:0006357,GO:0006725,GO:0006807,GO:0006915,GO:0006921,GO:0006928,GO:0006950,GO:0006974,GO:0006979,GO:0006996,GO:0007049,GO:0007059,GO:0007060,GO:0007076,GO:0007093,GO:0007127,GO:0007131,GO:0007140,GO:0007143,GO:0007154,GO:0007275,GO:0007276,GO:0007292,GO:0007346,GO:0007399,GO:0007409,GO:0007417,GO:0007420,GO:0007568,GO:0007569,GO:0007584,GO:0008022,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008219,GO:0008283,GO:0008301,GO:0008623,GO:0009058,GO:0009059,GO:0009314,GO:0009330,GO:0009605,GO:0009628,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010035,GO:0010212,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010639,GO:0010941,GO:0010942,GO:0012501,GO:0014070,GO:0014074,GO:0016043,GO:0016321,GO:0016458,GO:0016462,GO:0016477,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0019899,GO:0019900,GO:0019901,GO:0019953,GO:0021533,GO:0021549,GO:0021575,GO:0021587,GO:0021680,GO:0021681,GO:0021683,GO:0021684,GO:0021692,GO:0021694,GO:0021695,GO:0021696,GO:0021697,GO:0021702,GO:0021707,GO:0021953,GO:0022008,GO:0022037,GO:0022402,GO:0022411,GO:0022412,GO:0022414,GO:0030030,GO:0030097,GO:0030154,GO:0030182,GO:0030261,GO:0030262,GO:0030263,GO:0030332,GO:0030554,GO:0030900,GO:0030902,GO:0031010,GO:0031175,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031570,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0031974,GO:0031981,GO:0032182,GO:0032501,GO:0032502,GO:0032504,GO:0032553,GO:0032555,GO:0032559,GO:0032989,GO:0032990,GO:0032991,GO:0033043,GO:0033044,GO:0033198,GO:0033554,GO:0034599,GO:0034614,GO:0034641,GO:0034645,GO:0035639,GO:0035690,GO:0035825,GO:0036094,GO:0040011,GO:0040016,GO:0040029,GO:0042221,GO:0042493,GO:0042542,GO:0042623,GO:0042752,GO:0042802,GO:0042803,GO:0042826,GO:0042981,GO:0043021,GO:0043065,GO:0043067,GO:0043068,GO:0043130,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043565,GO:0043900,GO:0043902,GO:0043903,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044454,GO:0044464,GO:0044703,GO:0044774,GO:0044877,GO:0045069,GO:0045070,GO:0045091,GO:0045132,GO:0045739,GO:0045786,GO:0045814,GO:0045870,GO:0045892,GO:0045893,GO:0045930,GO:0045934,GO:0045935,GO:0045944,GO:0046483,GO:0046677,GO:0046683,GO:0046872,GO:0046982,GO:0046983,GO:0048232,GO:0048285,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048524,GO:0048534,GO:0048583,GO:0048584,GO:0048609,GO:0048646,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048870,GO:0050000,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051173,GO:0051179,GO:0051234,GO:0051252,GO:0051253,GO:0051254,GO:0051276,GO:0051301,GO:0051303,GO:0051304,GO:0051306,GO:0051307,GO:0051309,GO:0051310,GO:0051321,GO:0051640,GO:0051641,GO:0051649,GO:0051656,GO:0051674,GO:0051704,GO:0051716,GO:0051726,GO:0060255,GO:0060322,GO:0061505,GO:0061564,GO:0061982,GO:0065007,GO:0070013,GO:0070301,GO:0070603,GO:0070887,GO:0071103,GO:0071107,GO:0071236,GO:0071310,GO:0071318,GO:0071407,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0071840,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0097159,GO:0097194,GO:0097237,GO:0097367,GO:0098813,GO:0120036,GO:0120039,GO:0140013,GO:0140014,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902494,GO:1902679,GO:1902680,GO:1903046,GO:1903047,GO:1903506,GO:1903507,GO:1903508,GO:1903900,GO:1903902,GO:1904949,GO:1905462,GO:1905463,GO:1990837,GO:1990904,GO:2000112,GO:2000113,GO:2000779,GO:2000781,GO:2001020,GO:2001022,GO:2001032,GO:2001034,GO:2001141,GO:2001251 5.99.1.3 ko:K03164 ko01524,map01524 - - - ko00000,ko00001,ko01000,ko03032,ko03036 - - - DNA_gyraseB,DNA_topoisoIV,DTHCT,HATPase_c,TOPRIM_C,Toprim k59_81468_1 1618248.A0A0C5IB82_9CIRC 2.33e-18 90.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_245283_2 856793.MICA_990 4.35e-40 144.0 COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,2TT5T@28211|Alphaproteobacteria,4BQCW@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily rfbB - 4.2.1.46,4.2.1.76,5.1.3.2 ko:K01710,ko:K01784,ko:K12450 ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130 M00361,M00362,M00632,M00793 R00291,R00293,R02984,R06513 RC00289,RC00402 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd k59_222935_2 941824.TCEL_02215 1.33e-06 50.8 COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,2487H@186801|Clostridia,36EFC@31979|Clostridiaceae 186801|Clostridia L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO recR - - ko:K06187 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - HHH,RecR,Toprim_4 k59_58966_1 1692259.A0A0K1RL59_9CIRC 2.67e-13 75.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_512576_1 1038860.AXAP01000067_gene8427 8e-53 186.0 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,2U6BJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S TIGRFAM phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_614192_1 1111728.ATYS01000085_gene4044 5.83e-17 88.2 COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,1RMJ1@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Belongs to the 'phage' integrase family intA - - - - - - - - - - - Arm-DNA-bind_3,Phage_integrase k59_614205_1 702437.HMPREF9432_00897 3.23e-10 62.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes 1239|Firmicutes L snf2 family - - - - - - - - - - - - SNF2_N k59_120344_3 1116482.K9L572_9CAUD 1.33e-20 88.2 4QAUS@10239|Viruses,4QURX@35237|dsDNA viruses no RNA stage,4QQ2S@28883|Caudovirales,4QHWP@10662|Myoviridae 10662|Myoviridae S flavin adenine dinucleotide binding - - - - - - - - - - - - - k59_286868_1 935839.JAGJ01000029_gene22 1.29e-07 60.8 COG0810@1|root,COG3055@1|root,COG0810@2|Bacteria,COG3055@2|Bacteria 2|Bacteria G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - 3.2.1.4 ko:K01179,ko:K03832 ko00500,ko01100,map00500,map01100 - R06200,R11307,R11308 - ko00000,ko00001,ko01000,ko02000 2.C.1.1 GH5,GH9 - Malectin,NPCBM,Sigma70_r2 k59_59094_1 444875.E3SMF7_9CAUD 3.04e-05 55.5 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QNBD@10744|Podoviridae 10744|Podoviridae S outer membrane - - - - - - - - - - - - - k59_120427_1 1337936.IJ00_27500 3.74e-13 72.0 COG1249@1|root,COG1249@2|Bacteria,1G198@1117|Cyanobacteria,1HKQ5@1161|Nostocales 1117|Cyanobacteria C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family merA - - - - - - - - - - - Pyr_redox_2,Pyr_redox_dim,SNARE_assoc k59_120427_2 522772.Dacet_0951 1.16e-22 90.9 COG0724@1|root,COG0724@2|Bacteria,2GG4M@200930|Deferribacteres 200930|Deferribacteres S SMART RNP-1 like RNA-binding protein - - - - - - - - - - - - RRM_1 k59_614334_2 452471.Aasi_0628 5.33e-25 99.4 COG0629@1|root,COG0629@2|Bacteria,4NT9M@976|Bacteroidetes,47S1E@768503|Cytophagia 976|Bacteroidetes L Domain of unknown function (DUF3127) - - - - - - - - - - - - DUF3127 k59_614334_5 1345695.CLSA_c30050 2.54e-41 145.0 COG0863@1|root,COG0863@2|Bacteria,1VRVB@1239|Firmicutes,24GNY@186801|Clostridia 186801|Clostridia L DNA methylase - - - - - - - - - - - - N6_N4_Mtase k59_120436_1 105154.Q9MBU6_9VIRU 4.6e-16 77.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_366959_1 44689.DDB0187223 1.47e-30 113.0 2ERHU@1|root,2RID2@2759|Eukaryota,3XI40@554915|Amoebozoa 554915|Amoebozoa - - - - - - - - - - - - - - - k59_576274_1 1480731.X2KUH8_9CAUD 1.56e-07 52.4 4QAK6@10239|Viruses,4QPBY@28883|Caudovirales 28883|Caudovirales S N-acetylmuramoyl-L-alanine amidase activity - GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0008150,GO:0016032,GO:0016787,GO:0016798,GO:0019012,GO:0019058,GO:0019062,GO:0022610,GO:0044403,GO:0044406,GO:0044409,GO:0044411,GO:0044419,GO:0044423,GO:0044650,GO:0051701,GO:0051704,GO:0051828,GO:0051830,GO:0085027,GO:0098015,GO:0098024 - - - - - - - - - - - k59_515200_1 504346.PRO_0000326456 2.1e-15 84.7 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales 28883|Caudovirales S N-acetylmuramoyl-L-alanine amidase activity - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019028,GO:0019058,GO:0019062,GO:0022610,GO:0042802,GO:0044403,GO:0044406,GO:0044419,GO:0044423,GO:0044650,GO:0051704,GO:0098015,GO:0098024 - - - - - - - - - - - k59_42646_1 759938.F5BSB4_9CIRC 1.19e-09 60.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_42646_3 1692249.A0A0K1RL40_9CIRC 7.9e-38 138.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_535473_2 1122201.AUAZ01000017_gene2962 2.18e-07 63.5 COG4675@1|root,COG4675@2|Bacteria 2|Bacteria M tail collar domain protein - - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - Collar,Phage_fiber_2 k59_166027_2 742767.HMPREF9456_03404 2.06e-62 200.0 COG0270@1|root,COG0270@2|Bacteria,4P351@976|Bacteroidetes 976|Bacteroidetes L DNA (cytosine-5-)-methyltransferase activity - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_186653_1 698440.XP_007296594.1 4.88e-13 74.3 COG0277@1|root,KOG1231@2759|Eukaryota,38FXH@33154|Opisthokonta,3NUBF@4751|Fungi,3QKU6@4890|Ascomycota,20VX5@147548|Leotiomycetes 4751|Fungi C FAD linked oxidases, C-terminal domain DLD1 GO:0003674,GO:0003824,GO:0004457,GO:0004458,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016020,GO:0016054,GO:0016491,GO:0016614,GO:0016898,GO:0019752,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0055114,GO:0070013,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616,GO:1903457 1.1.2.4 ko:K00102 ko00620,map00620 - R00197 RC00044 ko00000,ko00001,ko01000 - - iMM904.YDL174C,iND750.YDL174C FAD-oxidase_C,FAD_binding_4 k59_617561_2 1038860.AXAP01000067_gene8427 1.37e-74 242.0 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,2U6BJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S TIGRFAM phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_166042_1 1618236.A0A0C5I2F3_9CIRC 1.5e-28 117.0 4QGVY@10239|Viruses,4QUKN@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_494151_1 563192.HMPREF0179_02963 1.26e-07 57.0 COG1196@1|root,COG3941@1|root,COG1196@2|Bacteria,COG3941@2|Bacteria 2|Bacteria O tape measure - - - ko:K03529 - - - - ko00000,ko03036 - - - PhageMin_Tail,Tape_meas_lam_C k59_227321_1 1548905.A0A0A1IUL8_9CAUD 1.47e-23 99.8 4QBA2@10239|Viruses,4QPPI@28883|Caudovirales,4QM0B@10699|Siphoviridae 10699|Siphoviridae S Thymidylate synthase - GO:0003674,GO:0003824,GO:0004799,GO:0008150,GO:0008152,GO:0008168,GO:0016740,GO:0016741,GO:0032259,GO:0042083 - - - - - - - - - - - k59_371409_1 10752.Q8LTE3_BPN4 1.59e-17 82.0 4QBMV@10239|Viruses,4QUU6@35237|dsDNA viruses no RNA stage,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_125290_1 907931.AEIZ01000026_gene1633 1.25e-58 201.0 COG1892@1|root,COG1892@2|Bacteria,1V0S3@1239|Firmicutes,4HUB7@91061|Bacilli,4AXDH@81850|Leuconostocaceae 91061|Bacilli H Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle ppcA - 4.1.1.31 ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00168,M00170,M00171,M00172,M00173,M00346,M00374 R00345 RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPcase_2 k59_456367_2 1692261.A0A0K1RLL5_9CIRC 2.15e-16 81.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_393868_3 370438.PTH_2463 9.96e-12 67.8 28K97@1|root,2Z9WV@2|Bacteria,1TRTN@1239|Firmicutes,24B2J@186801|Clostridia,2664F@186807|Peptococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_599072_3 1117958.PE143B_0130490 1.65e-10 63.2 COG3935@1|root,COG3935@2|Bacteria,1MZTW@1224|Proteobacteria,1T07T@1236|Gammaproteobacteria 1236|Gammaproteobacteria L DnaD domain protein - - - - - - - - - - - - - k59_599367_1 61647.LG71_03505 0.000199 53.1 COG1511@1|root,COG5281@1|root,COG1511@2|Bacteria,COG5281@2|Bacteria,1MX2R@1224|Proteobacteria,1RS2K@1236|Gammaproteobacteria 1236|Gammaproteobacteria M tape measure protein - - - - - - - - - - - - Phage_HK97_TLTM k59_229869_1 1498011.A0A096XUV4_9CAUD 1.18e-36 133.0 4QBHW@10239|Viruses,4QTT7@28883|Caudovirales,4QNKM@10744|Podoviridae 10744|Podoviridae S transferase activity, transferring alkyl or aryl (other than methyl) groups - - - - - - - - - - - - - k59_394143_2 395492.Rleg2_1171 4.23e-25 101.0 COG2197@1|root,COG2197@2|Bacteria,1NA3X@1224|Proteobacteria,2UHEF@28211|Alphaproteobacteria 28211|Alphaproteobacteria KT HNH endonuclease - - - - - - - - - - - - HNH_3 k59_518694_1 985867.AEWF01000005_gene2482 5.42e-27 108.0 COG1533@1|root,COG1533@2|Bacteria,1R8E3@1224|Proteobacteria,2U77U@28211|Alphaproteobacteria,47FZA@766|Rickettsiales 766|Rickettsiales L DNA photolyase activity - - 4.1.99.14 ko:K03716 - - - - ko00000,ko01000 - - - - k59_642060_1 591001.Acfer_1951 6.64e-06 57.0 COG5519@1|root,COG5519@2|Bacteria,1TRMV@1239|Firmicutes,4H697@909932|Negativicutes 909932|Negativicutes L Domain of unknown function (DUF927) - - - - - - - - - - - - DUF927 k59_642060_2 979533.F1D0U3_9CAUD 2.38e-14 68.9 4QAM4@10239|Viruses,4QWEA@35237|dsDNA viruses no RNA stage,4QPGM@28883|Caudovirales,4QNJD@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_87606_1 1618238.A0A0C5IB41_9CIRC 6.7e-05 47.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_87606_3 1618248.A0A0C5IB82_9CIRC 8.43e-13 72.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_352688_2 1609634.A0A0C5ANA6_9VIRU 1.49e-09 64.7 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_599401_2 105154.Q9MBU6_9VIRU 2.75e-100 309.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_578977_1 1158165.KB898873_gene350 8.51e-15 71.2 2DSMC@1|root,33GP4@2|Bacteria,1NCDH@1224|Proteobacteria,1T10M@1236|Gammaproteobacteria,1X1TS@135613|Chromatiales 135613|Chromatiales S Domain of unknown function (DUF4326) - - - - - - - - - - - - DUF4326 k59_642093_1 1029823.AFIE01000007_gene1922 5.13e-53 181.0 COG5377@1|root,COG5377@2|Bacteria,1MWP8@1224|Proteobacteria,1RN9Q@1236|Gammaproteobacteria,3NIHJ@468|Moraxellaceae 1236|Gammaproteobacteria L YqaJ-like viral recombinase domain - - - - - - - - - - - - YqaJ k59_87638_2 1540097.A0A0A0YW88_9CAUD 8.93e-241 692.0 4QGA5@10239|Viruses,4QT9N@28883|Caudovirales,4QP47@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_394179_1 1121895.Q765_03190 5.05e-53 181.0 COG0467@1|root,COG0467@2|Bacteria,4PK66@976|Bacteroidetes,1INEQ@117743|Flavobacteriia,2NZBJ@237|Flavobacterium 976|Bacteroidetes T Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction - - - - - - - - - - - - - k59_561574_1 1121365.AQXB01000009_gene565 1.42e-33 146.0 COG5412@1|root,COG5412@2|Bacteria,2IH91@201174|Actinobacteria 201174|Actinobacteria E phage tail tape measure protein - - - - - - - - - - - - - k59_131867_1 1472716.KBK24_0106755 1.33e-09 65.5 COG2730@1|root,COG2730@2|Bacteria,1R4XH@1224|Proteobacteria,2VY3Y@28216|Betaproteobacteria 28216|Betaproteobacteria G Cellulase (glycosyl hydrolase family 5) - - - - - - - - - - - - Cellulase k59_48018_2 1572239.A0A0A0YP18_9CIRC 7.11e-17 83.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_561915_1 1005994.GTGU_00289 3.68e-14 73.9 2DR9Y@1|root,33AUY@2|Bacteria,1NAA8@1224|Proteobacteria,1SDFU@1236|Gammaproteobacteria 1236|Gammaproteobacteria L NUMOD4 motif - - - - - - - - - - - - HNH_3,NUMOD4 k59_647399_1 1122201.AUAZ01000017_gene2960 7.23e-94 291.0 COG5362@1|root,COG5362@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Terminase_6C k59_397823_2 105154.Q9MBU3_9VIRU 1.16e-14 77.0 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_582548_1 1692250.A0A0K1RLR1_9CIRC 1.69e-51 178.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_338860_1 1618260.A0A0C5I2C5_9CIRC 1.22e-47 164.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_338860_2 1618247.A0A0C5IMK7_9CIRC 2.78e-10 66.6 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_338860_3 1379713.S5SYD9_9CIRC 5.15e-27 106.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_418782_2 1230469.M5AAF0_9CAUD 5.14e-05 47.0 4QGP7@10239|Viruses,4QWWZ@35237|dsDNA viruses no RNA stage,4QQ0Q@28883|Caudovirales,4QMNP@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_523874_1 452863.Achl_2542 1.38e-74 242.0 COG3046@1|root,COG3046@2|Bacteria,2GMF6@201174|Actinobacteria 201174|Actinobacteria S deoxyribodipyrimidine cry1 - - ko:K06876 - - - - ko00000 - - - DPRP,FAD_binding_7 k59_178844_1 161934.XP_010674730.1 1.46e-14 84.0 COG0417@1|root,KOG0968@2759|Eukaryota,37RRF@33090|Viridiplantae,3GCAV@35493|Streptophyta 35493|Streptophyta L DNA polymerase - GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0010225,GO:0016035,GO:0018130,GO:0019438,GO:0019985,GO:0032991,GO:0033554,GO:0034641,GO:0034644,GO:0034645,GO:0034654,GO:0042276,GO:0042575,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071214,GO:0071478,GO:0071482,GO:0071494,GO:0071704,GO:0071897,GO:0090304,GO:0104004,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02350 ko01100,ko01524,ko03460,map01100,map01524,map03460 M00293 - - ko00000,ko00001,ko00002,ko01000,ko03400 - - - DNA_pol_B,DNA_pol_B_exo1,zf-C4pol,zf-RanBP k59_504910_2 1506572.A0A097ZPG0_9CIRC 5.03e-31 117.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_504910_3 1506572.A0A097ZPG0_9CIRC 2.74e-153 434.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_504910_4 1506572.A0A097ZPF9_9CIRC 8.63e-63 200.0 4QC68@10239|Viruses,4QUKE@29258|ssDNA viruses 10239|Viruses S viral capsid assembly - - - - - - - - - - - - - k59_112102_1 1234888.K0A2J2_9VIRU 9.82e-57 195.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_215498_3 434131.NRI_0529 1.12e-78 261.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,2TSF9@28211|Alphaproteobacteria,47F12@766|Rickettsiales 766|Rickettsiales L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_423688_2 172088.AUGA01000082_gene6213 7.14e-24 102.0 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,2U6BJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S TIGRFAM phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_14384_1 999411.HMPREF1092_00177 7.39e-06 55.8 COG0391@1|root,COG0391@2|Bacteria,1TPNV@1239|Firmicutes,248G0@186801|Clostridia,36EUV@31979|Clostridiaceae 186801|Clostridia S Required for morphogenesis under gluconeogenic growth conditions - - - - - - - - - - - - UPF0052 k59_505266_1 660470.Theba_1057 2.03e-07 54.3 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2GCCM@200918|Thermotogae 200918|Thermotogae L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_465934_2 301.JNHE01000017_gene4667 1.86e-18 89.7 COG3645@1|root,COG3646@1|root,COG3645@2|Bacteria,COG3646@2|Bacteria,1R939@1224|Proteobacteria,1S2IZ@1236|Gammaproteobacteria,1YGJU@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Phage regulatory protein Rha (Phage_pRha) - - - - - - - - - - - - ANT,Phage_pRha k59_654804_1 762982.HMPREF9442_00539 2.21e-23 105.0 COG1061@1|root,COG1061@2|Bacteria,4NECV@976|Bacteroidetes,2FN7J@200643|Bacteroidia 976|Bacteroidetes L Helicase C-terminal domain protein - - - ko:K19789 - - - - ko00000,ko03400 - - - Helicase_C,QSregVF_b,ResIII k59_654804_3 428127.EUBDOL_02124 1.09e-05 52.4 COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,3VNVZ@526524|Erysipelotrichia 526524|Erysipelotrichia L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_551062_1 2003327.CAPSD_BPCHP 4.89e-08 61.6 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_241885_1 1007105.PT7_P059 2.44e-73 238.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2VNHP@28216|Betaproteobacteria,3T3DM@506|Alcaligenaceae 28216|Betaproteobacteria S COG4626 Phage terminase-like protein, large subunit - - - - - - - - - - - - Terminase_1 k59_37713_1 1183239.I1ZBD6_9VIRU 1.37e-18 85.9 4QBIH@10239|Viruses,4QVPB@35237|dsDNA viruses no RNA stage 10239|Viruses S recombinase activity - - - - - - - - - - - - - k59_160721_1 1296660.S5MA26_9CAUD 3.15e-58 201.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QI9F@10662|Myoviridae 10662|Myoviridae S Type III restriction enzyme, res subunit - - - - - - - - - - - - - k59_79655_3 767817.Desgi_4512 6e-22 92.4 COG2105@1|root,COG2105@2|Bacteria,1VDAD@1239|Firmicutes,24HW1@186801|Clostridia 186801|Clostridia S COG NOG17855 non supervised orthologous group - - - - - - - - - - - - GGACT k59_79655_4 452471.Aasi_0650 2.66e-23 106.0 COG0587@1|root,COG0587@2|Bacteria,4NFA0@976|Bacteroidetes,47K9H@768503|Cytophagia 976|Bacteroidetes L DNA-directed DNA polymerase dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon k59_509962_4 1458357.BG58_33000 5.21e-12 61.6 2CIZN@1|root,33BAP@2|Bacteria,1NJHF@1224|Proteobacteria 1224|Proteobacteria S Superinfection immunity protein - - - - - - - - - - - - Imm_superinfect,SHOCT k59_509962_6 1357714.A0A067XRB3_9CAUD 6.59e-38 135.0 4QCXM@10239|Viruses,4QZZ5@35237|dsDNA viruses no RNA stage,4QT8U@28883|Caudovirales,4QJ27@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_160723_1 1122247.C731_2962 1.43e-16 78.6 2DQ0N@1|root,32UN8@2|Bacteria,2IP80@201174|Actinobacteria,23DIM@1762|Mycobacteriaceae 201174|Actinobacteria S Toprim-like - - - - - - - - - - - - Toprim_2 k59_142788_6 406552.NJ7G_3369 2.59e-08 62.8 COG0584@1|root,arCOG00701@2157|Archaea,2XXRI@28890|Euryarchaeota,23W41@183963|Halobacteria 183963|Halobacteria C glycerophosphoryl diester phosphodiesterase glpQ1 - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD k59_407469_3 1692242.A0A0K1RL37_9CIRC 3.65e-69 221.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_202919_2 1692247.A0A0K1RL30_9CIRC 4.32e-51 175.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_509980_2 1391433.V5R4L5_9CAUD 9.72e-81 248.0 4QCAU@10239|Viruses,4QXFG@35237|dsDNA viruses no RNA stage,4QPJ6@28883|Caudovirales,4QKZJ@10699|Siphoviridae 10699|Siphoviridae S Pfam:GP88 - - - - - - - - - - - - - k59_595521_1 1618242.A0A0C5IBR9_9CIRC 3.71e-30 120.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_575185_1 985867.AEWF01000001_gene1847 1.55e-30 123.0 COG4870@1|root,COG4870@2|Bacteria,1MV6S@1224|Proteobacteria,2UC0Y@28211|Alphaproteobacteria,47G9R@766|Rickettsiales 766|Rickettsiales O Papain family cysteine protease - - - - - - - - - - - - - k59_247228_1 1636270.A0A0E3JPD6_9CAUD 4.72e-14 77.8 4QAKM@10239|Viruses,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_411002_2 1618248.A0A0C5IB82_9CIRC 2.69e-15 82.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_123721_3 469381.Dpep_0394 4.47e-23 96.3 COG0817@1|root,COG0817@2|Bacteria,3TCBE@508458|Synergistetes 508458|Synergistetes L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group - - - - - - - - - - - - - k59_123721_8 1172188.KB911820_gene2885 1.61e-221 640.0 COG0209@1|root,COG0209@2|Bacteria,2IC1H@201174|Actinobacteria 201174|Actinobacteria F Ribonucleotide reductase, barrel domain - - - - - - - - - - - - Ribonuc_red_lgC k59_123721_12 1397693.KK211187_gene1243 7.58e-35 132.0 COG1191@1|root,COG1191@2|Bacteria,1TP9K@1239|Firmicutes,4HCJV@91061|Bacilli 91061|Bacilli K Belongs to the sigma-70 factor family sigD - - ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 - - - ko00000,ko00001,ko02035,ko03021 - - - Sigma70_r2,Sigma70_r3,Sigma70_r4 k59_123721_18 1123269.NX02_21835 1.69e-32 127.0 COG3023@1|root,COG3409@1|root,COG3023@2|Bacteria,COG3409@2|Bacteria,1RHPU@1224|Proteobacteria,2UA2W@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Putative peptidoglycan binding domain - - - - - - - - - - - - PG_binding_1 k59_123721_22 1123023.JIAI01000012_gene9202 1.32e-57 193.0 COG1351@1|root,COG1351@2|Bacteria 2|Bacteria F thymidylate synthase (FAD) activity - - 2.1.1.148 ko:K03465 ko00240,ko00670,ko01100,map00240,map00670,map01100 - R06613 RC00022,RC00332 ko00000,ko00001,ko01000 - - - Thy1 k59_123721_25 1123013.AUIC01000003_gene746 9.34e-83 263.0 COG1875@1|root,COG1875@2|Bacteria,2GK8U@201174|Actinobacteria,4FMEX@85023|Microbacteriaceae 201174|Actinobacteria T Large family of predicted nucleotide-binding domains phoH2 - - ko:K07175 - - - - ko00000 - - - PIN_4,PhoH k59_493118_1 1035184.HMPREF1042_1237 2.72e-14 73.6 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4H9YP@91061|Bacilli,42E26@671232|Streptococcus anginosus group 91061|Bacilli L SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,SNF2_N k59_493118_3 585501.HMPREF6123_0851 8.1e-08 61.6 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,2487V@186801|Clostridia,2PQVX@265975|Oribacterium 186801|Clostridia L DNA polymerase A domain - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_41746_1 1692249.A0A0K1RLN8_9CIRC 7.98e-24 102.0 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_595793_1 323098.Nwi_1546 1.83e-20 90.9 COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,1MVH7@1224|Proteobacteria,2TRNA@28211|Alphaproteobacteria,3JW7V@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria KL DNA methylase - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase,ParBc k59_595793_2 329381.D9ICQ3_9CAUD 1e-17 83.6 4QAKE@10239|Viruses,4QUP7@35237|dsDNA viruses no RNA stage,4QPCE@28883|Caudovirales,4QI56@10662|Myoviridae 10662|Myoviridae S nucleic acid binding - - - - - - - - - - - - - k59_496345_2 1416009.V9VFZ7_9CAUD 0.000728 44.7 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales,4QNBQ@10744|Podoviridae 10744|Podoviridae S HNH endonuclease - - - - - - - - - - - - - k59_538152_1 526218.Sterm_1259 1.74e-06 50.8 COG1783@1|root,COG1783@2|Bacteria,3797J@32066|Fusobacteria 32066|Fusobacteria S Phage terminase, large subunit, PBSX family - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C k59_640807_1 1692242.A0A0K1RL37_9CIRC 1e-70 228.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_86617_1 1211844.CBLM010000090_gene2700 4.13e-28 114.0 COG2189@1|root,COG2189@2|Bacteria,1UKK3@1239|Firmicutes,3VTXZ@526524|Erysipelotrichia 526524|Erysipelotrichia L DNA methylase - - - - - - - - - - - - N6_N4_Mtase k59_538155_1 1449126.JQKL01000046_gene2072 9.26e-18 90.9 COG1783@1|root,COG1783@2|Bacteria,1TT85@1239|Firmicutes,24ETQ@186801|Clostridia 186801|Clostridia S Psort location Cytoplasmic, score - - - - - - - - - - - - Terminase_6 k59_105441_1 411465.PEPMIC_00741 4.47e-22 95.9 2DFCM@1|root,2ZRBY@2|Bacteria,1V500@1239|Firmicutes,25FKQ@186801|Clostridia,22ID7@1570339|Peptoniphilaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_105441_4 1121365.AQXB01000009_gene565 2.99e-20 104.0 COG5412@1|root,COG5412@2|Bacteria,2IH91@201174|Actinobacteria 201174|Actinobacteria E phage tail tape measure protein - - - - - - - - - - - - - k59_496749_1 512565.AMIS_2480 3.95e-23 110.0 COG1749@1|root,COG1749@2|Bacteria,2HGM7@201174|Actinobacteria,4DJW6@85008|Micromonosporales 201174|Actinobacteria N Flagellar hook protein flgE - - - - - - - - - - - - - k59_311243_3 1177928.TH2_05218 9.4e-29 111.0 2C095@1|root,32VKM@2|Bacteria,1N0Y9@1224|Proteobacteria,2UJ59@28211|Alphaproteobacteria,2JYQC@204441|Rhodospirillales 204441|Rhodospirillales S Domain of unknown function (DUF1833) - - - - - - - - - - - - DUF1833 k59_65728_1 765420.OSCT_0770 4.03e-09 63.2 COG5295@1|root,COG5295@2|Bacteria,2GB82@200795|Chloroflexi,377IZ@32061|Chloroflexia 32061|Chloroflexia UW Hep Hag repeat protein - - - - - - - - - - - - Pectinesterase k59_24563_1 861208.AGROH133_06202 3.87e-11 66.2 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2TSDW@28211|Alphaproteobacteria,4BCQ8@82115|Rhizobiaceae 28211|Alphaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_311245_1 596153.Alide_1720 6.36e-32 132.0 COG4643@1|root,COG4643@2|Bacteria,1NUZ8@1224|Proteobacteria,2VSPB@28216|Betaproteobacteria,4AGB3@80864|Comamonadaceae 28216|Betaproteobacteria P DNA integration - - - - - - - - - - - - DUF3987 k59_641327_1 1541065.JRFE01000001_gene2536 1.1e-17 86.7 COG0055@1|root,COG0055@2|Bacteria,1G1BK@1117|Cyanobacteria,3VIG9@52604|Pleurocapsales 1117|Cyanobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0016020,GO:0016469,GO:0032991,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_N k59_482502_2 1144932.ATTF01000014_gene1158 1.66e-10 63.9 2EDRD@1|root,337KY@2|Bacteria,1NF3A@1224|Proteobacteria,2UKF1@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_69614_1 765914.ThisiDRAFT_0425 8.55e-13 68.2 COG3617@1|root,COG3646@1|root,COG3617@2|Bacteria,COG3646@2|Bacteria,1N7SM@1224|Proteobacteria,1RRD1@1236|Gammaproteobacteria,1X1Z0@135613|Chromatiales 135613|Chromatiales K PFAM Phage regulatory protein - - - - - - - - - - - - Phage_pRha k59_499991_2 145579.REP_BPPHM 2.8e-44 159.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_543211_1 1461693.ATO10_02065 4.43e-05 47.8 COG5281@1|root,COG5281@2|Bacteria,1R47M@1224|Proteobacteria,2TUIV@28211|Alphaproteobacteria 28211|Alphaproteobacteria S COG5281, Phage-related minor tail protein - - - - - - - - - - - - - k59_543211_2 371042.NG99_23805 2.41e-05 50.1 29J09@1|root,305XQ@2|Bacteria,1RAQN@1224|Proteobacteria,1S23I@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF1833) - - - - - - - - - - - - DUF1833 k59_338035_1 1007103.AFHW01000034_gene2067 2.19e-13 83.6 COG3941@1|root,COG3941@2|Bacteria,1V33U@1239|Firmicutes,4HMR7@91061|Bacilli,2711P@186822|Paenibacillaceae 91061|Bacilli S tape measure - - - - - - - - - - - - - k59_338052_1 1379692.S5SXY7_9CIRC 2.41e-08 58.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_172906_5 63737.Npun_F2574 6.49e-11 70.1 COG0270@1|root,COG1196@1|root,COG0270@2|Bacteria,COG1196@2|Bacteria,1GEKG@1117|Cyanobacteria,1HNKS@1161|Nostocales 1117|Cyanobacteria D DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - Dam k59_278248_1 212035.ASNS_MIMIV 3.27e-33 132.0 4QB8C@10239|Viruses,4QZ8Y@35237|dsDNA viruses no RNA stage 10239|Viruses E asparagine synthase (glutamine-hydrolyzing) activity - - - - - - - - - - - - - k59_627987_2 1234888.K0A2J2_9VIRU 3.49e-43 157.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_299421_1 445686.E3SKU6_9CAUD 1.99e-18 88.2 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QI82@10662|Myoviridae 10662|Myoviridae S virus tail, fiber - - - - - - - - - - - - - k59_528665_2 1452718.JBOY01000124_gene1276 3.48e-18 87.0 2ERBN@1|root,33IXA@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_300026_2 1561065.A0A0B5A580_9CAUD 2.51e-09 58.5 4QB5I@10239|Viruses,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_529617_2 1121020.JIAG01000002_gene781 1.89e-05 54.7 COG3291@1|root,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria 201174|Actinobacteria P PFAM PKD domain containing protein wcoG - - - - - - - - - - - Laminin_G_3,PKD k59_344438_1 1121353.H924_07255 1.55e-58 203.0 COG0553@1|root,COG0553@2|Bacteria,2IC31@201174|Actinobacteria,22MAR@1653|Corynebacteriaceae 201174|Actinobacteria KL Superfamily II DNA RNA helicases, SNF2 family - - - - - - - - - - - - SNF2_N k59_51300_1 97138.C820_01005 2e-12 72.0 COG1783@1|root,COG1783@2|Bacteria,1TRQP@1239|Firmicutes,248E9@186801|Clostridia,36EE3@31979|Clostridiaceae 186801|Clostridia L Phage terminase, large subunit, PBSX family - - - ko:K06909 - - - - ko00000 - - - Terminase_2,Terminase_3,Terminase_3C k59_344444_3 1453505.JASY01000009_gene470 2.06e-30 119.0 COG0639@1|root,COG0639@2|Bacteria 2|Bacteria T phosphoprotein phosphatase activity - - 6.5.1.3 ko:K14680 - - - - ko00000,ko01000 - - - Metallophos_2,RNA_lig_T4_1 k59_586870_1 105154.Q9MBU6_9VIRU 1.71e-103 317.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_446755_1 216591.BCAL2507 4.49e-69 223.0 28HEE@1|root,2Z7QU@2|Bacteria,1MXU6@1224|Proteobacteria,2VISI@28216|Betaproteobacteria,1K35U@119060|Burkholderiaceae 28216|Betaproteobacteria S Domain of unknown function (DUF932) - - - - - - - - - - - - DUF932 k59_529645_1 1234888.K0A2J2_9VIRU 1.16e-74 244.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_98528_5 575540.Isop_0751 2.11e-14 77.4 COG1043@1|root,COG1043@2|Bacteria,2IYJJ@203682|Planctomycetes 203682|Planctomycetes M Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxA - 2.3.1.129 ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 M00060 R04567 RC00039,RC00055 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Acetyltransf_11,Hexapep k59_259768_2 391615.ABSJ01000031_gene743 1.62e-22 97.4 COG2925@1|root,COG2925@2|Bacteria,1MV0U@1224|Proteobacteria,1RM85@1236|Gammaproteobacteria,1J4T9@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L COG2925 Exonuclease I sbcB GO:0000175,GO:0000287,GO:0000738,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0008852,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016829,GO:0016835,GO:0016895,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0046872,GO:0051575,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575 3.1.11.1 ko:K01141 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_X-T_C,RNase_T k59_136848_1 1618257.A0A0C5IBI9_9CIRC 2.55e-89 272.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_13633_2 411460.RUMTOR_01348 3.12e-86 269.0 28J3N@1|root,2Z8ZU@2|Bacteria,1V15Z@1239|Firmicutes,249Z0@186801|Clostridia 186801|Clostridia S Phage portal protein - - - - - - - - - - - - Phage_portal k59_155709_1 1121438.JNJA01000028_gene96 2.56e-20 92.0 COG0827@1|root,COG0827@2|Bacteria 2|Bacteria L DNA restriction-modification system - - - - - - - - - - - - DUF4942,MTS k59_32909_1 419610.Mext_3540 1.31e-07 55.5 COG1403@1|root,COG1403@2|Bacteria,1N90G@1224|Proteobacteria,2UGUS@28211|Alphaproteobacteria 28211|Alphaproteobacteria L HNH nucleases - - - - - - - - - - - - HNH k59_384484_1 110365.A0A023AXA1 1.61e-08 61.6 2EWQP@1|root,2SYH6@2759|Eukaryota 2759|Eukaryota S RNA helicase - - - - - - - - - - - - RNA_helicase,Viral_Rep k59_630978_1 1235659.S4T941_9CAUD 5.26e-10 63.9 4QI6J@10662|Myoviridae 10662|Myoviridae S sequence-specific DNA binding transcription factor activity - - - - - - - - - - - - - k59_655895_1 1618242.A0A0C5IBR9_9CIRC 1.15e-22 100.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_655895_3 1475143.W8SNN0_9CIRC 2.21e-16 79.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_321742_1 2003327.CAPSD_BPCHP 1.05e-43 159.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_589025_1 388051.AUFE01000035_gene4020 5.75e-81 260.0 COG4653@1|root,COG4653@2|Bacteria 2|Bacteria G Phage capsid family - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_425554_1 1117958.PE143B_0121610 6.08e-24 105.0 2CHG1@1|root,32YZS@2|Bacteria,1NBVV@1224|Proteobacteria,1RYDN@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_347250_1 1218352.B597_019615 3.69e-34 124.0 2E5K5@1|root,330BC@2|Bacteria,1RG8X@1224|Proteobacteria,1S3Z1@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Siphovirus Gp157 - - - - - - - - - - - - Sipho_Gp157 k59_655904_3 1692261.A0A0K1RLL5_9CIRC 4.87e-34 129.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_533000_4 1166948.JPZL01000002_gene1842 8.58e-96 321.0 28P6A@1|root,2ZC10@2|Bacteria,1RBZE@1224|Proteobacteria,1RRNS@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_533000_5 1307759.JOMJ01000003_gene1802 5.18e-126 383.0 COG5565@1|root,COG5565@2|Bacteria,1R6R3@1224|Proteobacteria,43BCR@68525|delta/epsilon subdivisions,2X6RN@28221|Deltaproteobacteria,2MA58@213115|Desulfovibrionales 28221|Deltaproteobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C k59_533000_6 1268072.PSAB_06050 7.96e-13 72.0 COG3728@1|root,COG3728@2|Bacteria,1VAD9@1239|Firmicutes,4HNDI@91061|Bacilli 91061|Bacilli L terminase small subunit - - - ko:K07474 - - - - ko00000 - - - Terminase_2 k59_533000_10 644524.C5IHQ1_9CAUD 1.94e-21 101.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QNBD@10744|Podoviridae 10744|Podoviridae S outer membrane - - - - - - - - - - - - - k59_35089_1 1234888.K0A2J2_9VIRU 9.66e-31 123.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_216929_1 1003195.SCAT_2252 2.29e-89 280.0 COG4626@1|root,COG4626@2|Bacteria,2GM6F@201174|Actinobacteria 201174|Actinobacteria L phage terminase - - - - - - - - - - - - Terminase_1 k59_101625_1 323097.Nham_3328 8.24e-26 110.0 COG5301@1|root,COG5301@2|Bacteria,1N6XX@1224|Proteobacteria,2USJX@28211|Alphaproteobacteria 28211|Alphaproteobacteria G cellulose 1,4-beta-cellobiosidase activity - - - - - - - - - - - - - k59_322353_1 883078.HMPREF9695_02222 3.98e-18 79.3 COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,2U956@28211|Alphaproteobacteria,3JY6T@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria FG Scavenger mRNA decapping enzyme C-term binding MA20_36190 - - ko:K02503 - - - - ko00000,ko04147 - - - HIT k59_404888_1 1404245.CGLY_12240 1.63e-12 72.4 COG3757@1|root,COG3757@2|Bacteria,2IIP7@201174|Actinobacteria,22MBT@1653|Corynebacteriaceae 201174|Actinobacteria M Glycosyl hydrolases family 25 acm - - - - - - - - - - - Glyco_hydro_25,Peptidase_M23 k59_284204_1 580332.Slit_2140 3.08e-19 82.4 COG1225@1|root,COG1225@2|Bacteria,1RH4P@1224|Proteobacteria,2VT1P@28216|Betaproteobacteria,44WFG@713636|Nitrosomonadales 28216|Betaproteobacteria O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA k59_242769_1 1340493.JNIF01000003_gene3508 2.39e-08 60.1 COG1322@1|root,COG1322@2|Bacteria,3Y45F@57723|Acidobacteria 57723|Acidobacteria S RmuC family - - - ko:K09760 - - - - ko00000 - - - RmuC k59_79883_1 1692242.A0A0K1RKZ2_9CIRC 2.82e-22 95.5 4QFEW@10239|Viruses,4QUKZ@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_38610_1 1548905.A0A0A1IUL8_9CAUD 1.18e-21 98.2 4QBA2@10239|Viruses,4QPPI@28883|Caudovirales,4QM0B@10699|Siphoviridae 10699|Siphoviridae S Thymidylate synthase - GO:0003674,GO:0003824,GO:0004799,GO:0008150,GO:0008152,GO:0008168,GO:0016740,GO:0016741,GO:0032259,GO:0042083 - - - - - - - - - - - k59_635464_2 1618256.A0A0C5IM93_9CIRC 2.47e-24 105.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_430088_1 294631.Q5ZGB2_9CAUD 3.18e-82 250.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_161693_1 1096546.WYO_4003 8.08e-06 52.8 COG3298@1|root,COG3298@2|Bacteria,1MVZJ@1224|Proteobacteria,2TSM7@28211|Alphaproteobacteria,1JRQU@119045|Methylobacteriaceae 28211|Alphaproteobacteria L Predicted 3'-5' exonuclease related to the exonuclease domain of PolB - - - ko:K07501 - - - - ko00000 - - - DNA_pol_B_exo2 k59_123536_8 441768.ACL_0293 2.82e-14 67.4 COG1278@1|root,COG1278@2|Bacteria,3WU23@544448|Tenericutes 544448|Tenericutes K Cold shock protein domain csp - - ko:K03704 - - - - ko00000,ko03000 - - - CSD k59_103053_1 1618238.A0A0C5IB41_9CIRC 9.99e-15 81.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_410799_1 1788454.A0A190WHE4_9CIRC 2.83e-35 136.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_431103_1 765914.ThisiDRAFT_0530 2.94e-88 273.0 COG0675@1|root,COG0675@2|Bacteria,1MUU0@1224|Proteobacteria,1RS1J@1236|Gammaproteobacteria,1X038@135613|Chromatiales 135613|Chromatiales L Probable transposase - - - ko:K07496 - - - - ko00000 - - - HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon k59_369848_3 1122201.AUAZ01000021_gene3157 0.000148 53.9 2EXSU@1|root,33R23@2|Bacteria,1NS77@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_369848_7 1192759.AKIB01000023_gene2889 7.77e-94 291.0 28W6R@1|root,2ZI7D@2|Bacteria,1N49N@1224|Proteobacteria,2UQMC@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_369848_10 1166948.JPZL01000002_gene1842 2.3e-10 67.8 28P6A@1|root,2ZC10@2|Bacteria,1RBZE@1224|Proteobacteria,1RRNS@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_123724_2 1618238.A0A0C5IB41_9CIRC 7.67e-07 58.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_534099_1 1692255.A0A0K1RL52_9CIRC 1.44e-36 133.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_164829_1 1165094.RINTHH_3920 1.91e-64 212.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_164829_3 1385658.U5KPZ6_9VIRU 1.16e-175 513.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_164829_4 105154.Q9MBU3_9VIRU 3.78e-15 72.8 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_369874_2 278963.ATWD01000001_gene4475 2.62e-11 60.8 COG0791@1|root,COG0791@2|Bacteria 2|Bacteria M cysteine-type peptidase activity - - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - LysM,NLPC_P60 k59_534113_2 1120746.CCNL01000014_gene2090 1.63e-16 76.3 2E38J@1|root,32Y88@2|Bacteria 2|Bacteria S VRR-NUC domain protein - - - - - - - - - - - - VRR_NUC k59_103525_1 1041147.AUFB01000014_gene330 1.67e-15 77.0 2FIAW@1|root,34A38@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_62715_1 1986029.Q9MBM3_9VIRU 1.61e-38 140.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_596145_1 585502.HMPREF0645_2609 1.4e-224 647.0 COG0553@1|root,COG0863@1|root,COG0553@2|Bacteria,COG0863@2|Bacteria,4NHHF@976|Bacteroidetes,2FRI5@200643|Bacteroidia 976|Bacteroidetes KL DNA methylase - - - - - - - - - - - - Helicase_C,N6_N4_Mtase,SNF2_N k59_391425_3 1609634.A0A0C5AFV4_9VIRU 1.64e-12 78.2 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_288587_1 862751.SACTE_2004 3.22e-10 62.0 COG1091@1|root,COG1091@2|Bacteria,2GNY8@201174|Actinobacteria 201174|Actinobacteria M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose rmlD GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008831,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019305,GO:0019438,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901576 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind k59_83941_2 1204521.I7B2R4_9CAUD 2.39e-53 176.0 4QF3X@10239|Viruses,4QWSV@35237|dsDNA viruses no RNA stage,4QT5P@28883|Caudovirales 28883|Caudovirales S oxidoreductase activity - - - - - - - - - - - - - k59_268435_1 1692242.A0A0K1RL37_9CIRC 1.91e-61 204.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_350154_1 1122238.AULR01000002_gene411 6.87e-29 115.0 COG0741@1|root,COG0741@2|Bacteria,2GM11@201174|Actinobacteria,4FTPW@85023|Microbacteriaceae 201174|Actinobacteria M Transglycosylase SLT domain - - - - - - - - - - - - SLT k59_432177_1 748727.CLJU_c03370 4.59e-18 90.9 COG2887@1|root,COG2887@2|Bacteria,1TPIC@1239|Firmicutes,247TB@186801|Clostridia,36EZ3@31979|Clostridiaceae 186801|Clostridia L Protein of unknown function (DUF2800) - - - - - - - - - - - - DUF2800 k59_268443_1 267608.RSc3232 5.31e-17 76.6 COG2197@1|root,COG2197@2|Bacteria,1NA3X@1224|Proteobacteria,2VWX0@28216|Betaproteobacteria,1KAW7@119060|Burkholderiaceae 28216|Betaproteobacteria KT phage-related functions and prophages - - - - - - - - - - - - HNH_3 k59_84688_5 1268072.PSAB_06285 2.56e-12 68.9 COG1028@1|root,COG1028@2|Bacteria,1UJNN@1239|Firmicutes,4HFTZ@91061|Bacilli,26VGN@186822|Paenibacillaceae 91061|Bacilli IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) fabG3 - 1.1.1.100,1.1.1.385 ko:K00059,ko:K19548 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572,M00787 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R10917,R11671 RC00029,RC00117,RC00154 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k59_269119_2 202952.BBLI01000132_gene4005 5.93e-06 52.0 COG5527@1|root,COG5527@2|Bacteria 2|Bacteria L Initiator Replication protein - - - - - - - - - - - - Rep_3 k59_536056_1 1121864.OMO_01343 2.98e-33 130.0 COG3378@1|root,COG3378@2|Bacteria,1TQP9@1239|Firmicutes,4HA5U@91061|Bacilli,4B1ET@81852|Enterococcaceae 91061|Bacilli S Phage plasmid primase, P4 family - - - ko:K06919 - - - - ko00000 - - - D5_N,Pox_D5 k59_596895_2 1572704.A0A0D3MVQ2_9CAUD 5.71e-07 53.9 4QIIB@10662|Myoviridae 10662|Myoviridae S Bacterial SH3 domain - - - - - - - - - - - - - k59_576643_3 1088869.GMO_09510 2.02e-13 77.4 COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,2TQWC@28211|Alphaproteobacteria,2JUVV@204441|Rhodospirillales 204441|Rhodospirillales L UvrD-like helicase C-terminal domain - - 3.1.11.5 ko:K01144 - - - - ko00000,ko01000 - - - AAA_30,UvrD_C_2,Viral_helicase1 k59_638823_2 105154.Q9MBU3_9VIRU 9.1e-11 67.0 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_638823_3 1385658.U5KPZ6_9VIRU 1.64e-178 520.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_638823_5 105154.Q9MBU0_9VIRU 2.55e-50 176.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_2626_1 1458848.A0A0A7X6X9_9CAUD 4.34e-30 115.0 4QEMD@10239|Viruses,4R0JN@35237|dsDNA viruses no RNA stage,4QUGF@28883|Caudovirales,4QNXF@10744|Podoviridae 10744|Podoviridae S AAA domain - - - - - - - - - - - - - k59_576644_1 202952.BBLI01000148_gene4049 1.49e-21 99.8 COG5655@1|root,COG5655@2|Bacteria,1N22J@1224|Proteobacteria,1SRUQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria L COG5655 Plasmid rolling circle replication initiator protein and truncated derivatives - - - - - - - - - - - - Rep_1 k59_596920_2 113395.AXAI01000019_gene6114 4.85e-33 126.0 28MC2@1|root,2ZAQD@2|Bacteria,1R5I0@1224|Proteobacteria,2TUSQ@28211|Alphaproteobacteria,3K1WH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_166942_3 204773.HEAR0694 1.07e-52 183.0 28HEE@1|root,2Z7QU@2|Bacteria,1MXU6@1224|Proteobacteria,2VISI@28216|Betaproteobacteria,473AC@75682|Oxalobacteraceae 28216|Betaproteobacteria S Evidence 4 Homologs of previously reported genes of - - - - - - - - - - - - DUF932 k59_166942_10 1177928.TH2_05208 6.59e-15 87.8 COG4733@1|root,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria,2TV2W@28211|Alphaproteobacteria,2JV2T@204441|Rhodospirillales 204441|Rhodospirillales S COG4733 Phage-related protein, tail component - - - - - - - - - - - - Lambda_tail_I,Phage-tail_3 k59_166942_11 68199.JNZO01000018_gene6917 0.000329 47.4 COG0791@1|root,COG1196@1|root,COG0791@2|Bacteria,COG1196@2|Bacteria,2GMK4@201174|Actinobacteria 201174|Actinobacteria M NlpC/P60 family - - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - DUF4226,NLPC_P60 k59_166942_13 1555208.A0A097EW01_9CAUD 1.54e-22 113.0 4QAK6@10239|Viruses,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - GO:0008150,GO:0044403,GO:0044409,GO:0044411,GO:0044419,GO:0051701,GO:0051704,GO:0051828,GO:0051830,GO:0085027 - - - - - - - - - - - k59_536755_3 888743.HMPREF9141_0984 4.2e-06 55.8 2EVUA@1|root,33P81@2|Bacteria,4P82D@976|Bacteroidetes,2FV68@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_104747_2 10228.TriadP52877 6.92e-22 99.0 2D04N@1|root,2SCSW@2759|Eukaryota,3AE35@33154|Opisthokonta 33154|Opisthokonta - - - - - - - - - - - - - - - k59_475316_1 406327.Mevan_1221 2.86e-49 175.0 COG0475@1|root,arCOG01955@2157|Archaea,2XWIX@28890|Euryarchaeota,23RH1@183939|Methanococci 183939|Methanococci P PFAM TrkA-N domain protein - - - - - - - - - - - - Na_H_Exchanger,TrkA_N k59_249452_3 1211813.CAPH01000006_gene1549 1.4e-08 57.4 COG1704@1|root,COG1704@2|Bacteria,4NMD3@976|Bacteroidetes,2FNPV@200643|Bacteroidia,22UF4@171550|Rikenellaceae 976|Bacteroidetes S LemA family lemA - - ko:K03744 - - - - ko00000 - - - LemA k59_495158_1 1609634.A0A0C5ANA6_9VIRU 6.02e-10 64.7 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_577145_2 639283.Snov_1953 1.52e-13 79.0 COG5281@1|root,COG5281@2|Bacteria,1MX2R@1224|Proteobacteria,2TW9T@28211|Alphaproteobacteria,3F0FI@335928|Xanthobacteraceae 28211|Alphaproteobacteria S tape measure protein - - - - - - - - - - - - - k59_516110_31 1347393.HG726021_gene517 5.15e-17 79.7 2BR89@1|root,32K6M@2|Bacteria,4NQWW@976|Bacteroidetes,2FT14@200643|Bacteroidia,4ASE9@815|Bacteroidaceae 976|Bacteroidetes - - - - - - - - - - - - - - - k59_146823_1 861299.J421_2187 4.99e-07 56.6 COG0739@1|root,COG0739@2|Bacteria 2|Bacteria M heme binding envC_2 - 3.4.24.75 ko:K08259,ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M23 k59_146823_2 691965.D4P7C0_9CAUD 1.84e-42 142.0 4QDUR@10239|Viruses,4QVMY@35237|dsDNA viruses no RNA stage,4QU8R@28883|Caudovirales,4QKNQ@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_597795_3 394503.Ccel_3062 1.6e-51 193.0 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,2487V@186801|Clostridia,36EDD@31979|Clostridiaceae 186801|Clostridia L DNA polymerase - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_146830_1 1423815.BACR01000037_gene1793 8.89e-26 104.0 COG0588@1|root,COG0588@2|Bacteria,1TQFP@1239|Firmicutes,4HAW7@91061|Bacilli,3F3SK@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmA GO:0001871,GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009986,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031,GO:2001065 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 k59_434258_1 1219084.AP014508_gene863 4.03e-20 100.0 COG0367@1|root,COG0367@2|Bacteria,2GDF1@200918|Thermotogae 200918|Thermotogae E TIGRFAM asparagine synthase (glutamine-hydrolyzing) - - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 k59_249784_1 1385658.U5KNR1_9VIRU 1.15e-69 219.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_249784_2 1385658.U5KNR1_9VIRU 5.15e-07 53.5 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_249784_3 1385658.U5KPZ6_9VIRU 8.93e-10 58.2 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_597804_1 1589297.A0A0B5H2N3_9CAUD 9.85e-76 234.0 4QEMD@10239|Viruses,4QUGF@28883|Caudovirales,4QNXF@10744|Podoviridae 10744|Podoviridae S AAA domain - - - - - - - - - - - - - k59_495607_1 475178.B2BTN9_9CAUD 9.37e-40 158.0 4QB9J@10239|Viruses,4QXFE@35237|dsDNA viruses no RNA stage,4QS1Z@28883|Caudovirales,4QN8F@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_537317_1 32042.PstZobell_10267 1.93e-25 102.0 COG3575@1|root,COG3575@2|Bacteria,1RDEB@1224|Proteobacteria,1RR6S@1236|Gammaproteobacteria,1Z2V3@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K09962 - - - - ko00000 - - - NTP_transf_6 k59_556902_2 742743.HMPREF9453_00576 2.12e-25 106.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4H2W4@909932|Negativicutes 909932|Negativicutes L SNF2 family - - - - - - - - - - - - Helicase_C,SNF2_N k59_249790_2 1298867.AUES01000024_gene2962 7.48e-26 110.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2TTEX@28211|Alphaproteobacteria,3JTCQ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Terminase - - - - - - - - - - - - Terminase_1 k59_413371_1 431943.CKL_3292 2.7e-20 95.1 COG0270@1|root,COG0270@2|Bacteria,1TPNE@1239|Firmicutes,24B1A@186801|Clostridia,36JFQ@31979|Clostridiaceae 186801|Clostridia H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_413371_3 78398.KS43_19495 1.91e-55 179.0 2C5J1@1|root,3067M@2|Bacteria,1N4SF@1224|Proteobacteria,1SFV6@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_147391_1 935848.JAEN01000011_gene1857 1.06e-15 82.4 COG4678@1|root,COG4678@2|Bacteria,1N51M@1224|Proteobacteria,2UC8H@28211|Alphaproteobacteria,2PWTF@265|Paracoccus 28211|Alphaproteobacteria G Muramidase (Phage lambda lysozyme) - - - - - - - - - - - - - k59_413895_1 1122997.AUDD01000007_gene815 7.03e-82 255.0 COG0553@1|root,COG0553@2|Bacteria,2H20C@201174|Actinobacteria,4DTBP@85009|Propionibacteriales 201174|Actinobacteria KL DEAD-like helicases superfamily - - - - - - - - - - - - Helicase_C,N6_N4_Mtase k59_65216_1 1002340.AFCF01000027_gene1324 1.64e-15 81.6 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2TSDW@28211|Alphaproteobacteria,34FTT@302485|Phaeobacter 28211|Alphaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_598350_2 1122218.KB893653_gene548 1.07e-19 102.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2TRJF@28211|Alphaproteobacteria,1JTT7@119045|Methylobacteriaceae 28211|Alphaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_250356_2 1234888.K0A2J2_9VIRU 6.19e-49 171.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_372731_1 1986029.Q9MBM3_9VIRU 4.23e-65 213.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_332636_5 1234888.K0A2J2_9VIRU 5.62e-104 324.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_270241_1 1692249.A0A0K1RLN8_9CIRC 3.28e-27 111.0 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_228972_1 1116369.KB890024_gene1790 7.21e-17 87.0 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2TQZE@28211|Alphaproteobacteria,43J93@69277|Phyllobacteriaceae 28211|Alphaproteobacteria M membrane MA20_30780 - - - - - - - - - - - Peptidase_M23 k59_455597_1 1385658.U5KPZ6_9VIRU 7.77e-60 202.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_250373_2 532078.B3VCM2_9CAUD 2.22e-09 60.8 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales,4QNBQ@10744|Podoviridae 10744|Podoviridae S HNH endonuclease - - - - - - - - - - - - - k59_640633_2 1340534.S4X394_9CAUD 8e-30 131.0 4QEIG@10239|Viruses,4R0E7@35237|dsDNA viruses no RNA stage,4QTGA@28883|Caudovirales 28883|Caudovirales S regulation of transcription, DNA-dependent - - - - - - - - - - - - - k59_640633_3 279238.Saro_0647 3.24e-12 73.9 COG4695@1|root,COG4695@2|Bacteria,1MUP5@1224|Proteobacteria,2TT33@28211|Alphaproteobacteria,2K2QM@204457|Sphingomonadales 204457|Sphingomonadales S Phage portal protein - - - - - - - - - - - - Phage_portal k59_207943_1 1692253.A0A0K1RLM4_9CIRC 2.75e-21 97.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_372747_2 439292.Bsel_3020 3.12e-61 208.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4H9YP@91061|Bacilli 91061|Bacilli L SNF2 family - - - - - - - - - - - - Helicase_C,SNF2_N k59_24494_2 1406780.U5PZU8_9CAUD 7.23e-17 85.5 4QBMV@10239|Viruses,4QUU6@35237|dsDNA viruses no RNA stage,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_557715_1 1336237.JAEE01000006_gene816 0.000242 46.6 COG0711@1|root,COG0711@2|Bacteria,1RHZ0@1224|Proteobacteria,1S402@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) atpF GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031225,GO:0032991,GO:0033177,GO:0034220,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902600 - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - e_coli_core.b3736,iAF1260.b3736,iB21_1397.B21_03564,iBWG_1329.BWG_3427,iE2348C_1286.E2348C_4046,iEC042_1314.EC042_4123,iEC55989_1330.EC55989_4211,iECABU_c1320.ECABU_c42210,iECBD_1354.ECBD_4296,iECB_1328.ECB_03620,iECDH10B_1368.ECDH10B_3923,iECDH1ME8569_1439.ECDH1ME8569_3624,iECD_1391.ECD_03620,iECED1_1282.ECED1_4426,iECH74115_1262.ECH74115_5172,iECIAI1_1343.ECIAI1_3920,iECIAI39_1322.ECIAI39_4340,iECO103_1326.ECO103_4422,iECO111_1330.ECO111_4570,iECO26_1355.ECO26_4842,iECOK1_1307.ECOK1_4185,iECP_1309.ECP_3935,iECS88_1305.ECS88_4158,iECSE_1348.ECSE_4026,iECSF_1327.ECSF_3584,iECSP_1301.ECSP_4786,iECUMN_1333.ECUMN_4266,iECW_1372.ECW_m4039,iECs_1301.ECs4678,iEKO11_1354.EKO11_4609,iETEC_1333.ETEC_4027,iEcDH1_1363.EcDH1_4231,iEcE24377_1341.EcE24377A_4252,iEcHS_1320.EcHS_A3952,iEcSMS35_1347.EcSMS35_4104,iEcolC_1368.EcolC_4258,iG2583_1286.G2583_4532,iJO1366.b3736,iJR904.b3736,iSDY_1059.SDY_4012,iSFV_1184.SFV_3762,iSF_1195.SF3816,iSFxv_1172.SFxv_4159,iSSON_1240.SSON_3883,iS_1188.S3952,iSbBS512_1146.SbBS512_E4185,iUMN146_1321.UM146_18870,iUMNK88_1353.UMNK88_4548,iUTI89_1310.UTI89_C4291,iWFL_1372.ECW_m4039,iY75_1357.Y75_RS18390,iZ_1308.Z5234,ic_1306.c4664 ATP-synt_B k59_105633_1 4897.EEB08892 0.000121 45.4 COG1061@1|root,2QT4U@2759|Eukaryota,38GE0@33154|Opisthokonta,3NWXY@4751|Fungi,3QQHS@4890|Ascomycota,3MCH3@451866|Taphrinomycotina 4751|Fungi L ATP-dependent DNA helicase Irc3 irc3 GO:0000002,GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005739,GO:0005759,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0007005,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010467,GO:0010501,GO:0016043,GO:0016070,GO:0016072,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022613,GO:0031974,GO:0031981,GO:0032042,GO:0033676,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042623,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070035,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 - ko:K17677 - - - - ko00000,ko01000,ko03029 - - - Helicase_C,ResIII k59_352195_1 234267.Acid_6164 0.000147 52.4 COG0823@1|root,COG2374@1|root,COG3170@1|root,COG3291@1|root,COG3391@1|root,COG3867@1|root,COG4257@1|root,COG4625@1|root,COG0823@2|Bacteria,COG2374@2|Bacteria,COG3170@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,COG3867@2|Bacteria,COG4257@2|Bacteria,COG4625@2|Bacteria,3Y354@57723|Acidobacteria 2|Bacteria M PKD domain containing protein - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 3.2.1.4 ko:K01179,ko:K07004,ko:K13277,ko:K20276,ko:K21449 ko00500,ko01100,ko02024,map00500,map01100,map02024 - R06200,R11307,R11308 - ko00000,ko00001,ko01000,ko01002,ko02000,ko03110 1.B.40.2 GH5,GH9 - Big_3_2,Exo_endo_phos,He_PIG,LTD k59_414337_1 145579.CAPSD_BPPHM 9.11e-29 119.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_435775_1 1618248.A0A0C5IB82_9CIRC 2.5e-23 99.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_188910_1 233412.HD_1452 0.000721 47.8 2CI0W@1|root,2Z81W@2|Bacteria,1R9FZ@1224|Proteobacteria,1S0NA@1236|Gammaproteobacteria,1Y9SV@135625|Pasteurellales 135625|Pasteurellales S Phage X family - - - - - - - - - - - - Phage_CRI,Phage_X k59_373226_2 767031.HMPREF9137_2263 0.000988 48.9 COG0863@1|root,COG0863@2|Bacteria,4NK2X@976|Bacteroidetes,2FPTJ@200643|Bacteroidia 976|Bacteroidetes L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.113 ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase,SNase k59_557741_2 1234880.K0A2H8_9CIRC 1.01e-24 103.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_148270_4 1986029.Q9MBM8_9VIRU 2.13e-43 156.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_641888_2 879308.HMPREF9130_1219 1.45e-11 61.6 2E38J@1|root,30W1S@2|Bacteria,1VI6Q@1239|Firmicutes,24T2F@186801|Clostridia 186801|Clostridia S VRR_NUC - - - - - - - - - - - - - k59_208565_1 1234888.K0A2J2_9VIRU 7.29e-56 192.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_539114_1 1424334.W822_20045 1.82e-30 128.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2VNHP@28216|Betaproteobacteria,3T3DM@506|Alcaligenaceae 28216|Betaproteobacteria S COG4626 Phage terminase-like protein, large subunit - - - - - - - - - - - - Terminase_1 k59_152042_2 5888.CAK82084 1.85e-07 56.6 COG5190@1|root,KOG1605@2759|Eukaryota 2759|Eukaryota K phosphoprotein phosphatase activity - GO:0003674,GO:0003824,GO:0004721,GO:0004722,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0006355,GO:0006357,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008420,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0031974,GO:0031981,GO:0036211,GO:0042578,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070013,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1903506,GO:2000112,GO:2001141 3.1.3.16 ko:K15731,ko:K17616 - - - - ko00000,ko01000,ko01009,ko03021 - - - NIF k59_92681_3 864069.MicloDRAFT_00037670 3.13e-62 216.0 COG1061@1|root,COG1061@2|Bacteria,1N52C@1224|Proteobacteria,2U3TE@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Type III restriction enzyme, res subunit - - - - - - - - - - - - Helicase_C,ResIII k59_544966_1 1122201.AUAZ01000017_gene2949 8.64e-47 166.0 COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,1RXX2@1236|Gammaproteobacteria,46B9P@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative metallopeptidase domain - - - - - - - - - - - - DUF2201,DUF2201_N k59_212325_1 1618240.A0A0C5IMJ1_9CIRC 5.56e-107 314.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_70865_1 765914.ThisiDRAFT_0530 2.6e-51 175.0 COG0675@1|root,COG0675@2|Bacteria,1MUU0@1224|Proteobacteria,1RS1J@1236|Gammaproteobacteria,1X038@135613|Chromatiales 135613|Chromatiales L Probable transposase - - - ko:K07496 - - - - ko00000 - - - HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon k59_133004_1 1234888.K0A2J2_9VIRU 1.6e-47 171.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_378570_1 762660.E5EZ16_9CAUD 0.000487 48.9 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QI82@10662|Myoviridae 10662|Myoviridae S virus tail, fiber - GO:0005575,GO:0019012 - - - - - - - - - - - k59_174408_3 1165094.RINTHH_3920 6.52e-69 223.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_174408_5 1385658.U5KPZ6_9VIRU 2.12e-159 468.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_296748_1 1231185.BAMP01000097_gene2372 2.04e-41 155.0 COG1475@1|root,COG4725@1|root,COG1475@2|Bacteria,COG4725@2|Bacteria,1R553@1224|Proteobacteria,2TRP6@28211|Alphaproteobacteria,43KW8@69277|Phyllobacteriaceae 28211|Alphaproteobacteria KT MT-A70 - - - - - - - - - - - - MT-A70,ParBc k59_378574_1 1385658.U5KNR1_9VIRU 4.69e-18 83.2 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_315845_1 1235793.C809_02225 3.3e-43 160.0 COG4383@1|root,COG4383@2|Bacteria,1TS7T@1239|Firmicutes,24CCB@186801|Clostridia 186801|Clostridia S Mu-like prophage protein gp29 - - - - - - - - - - - - - k59_378580_1 691965.D4P7I3_9CAUD 1.04e-79 264.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_109313_1 388739.RSK20926_02032 4.29e-27 120.0 COG0286@1|root,COG4889@1|root,COG0286@2|Bacteria,COG4889@2|Bacteria,1MWUJ@1224|Proteobacteria,2TT41@28211|Alphaproteobacteria 28211|Alphaproteobacteria L InterPro DEAD DEAH box helicase - - - - - - - - - - - - Helicase_C,Mrr_cat_2,N6_Mtase,ResIII k59_93342_2 105154.Q9MBU6_9VIRU 1.34e-124 379.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_347405_1 942016.E9NIG5_9CAUD 1.49e-10 65.9 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_347405_2 1122201.AUAZ01000017_gene2947 1.28e-74 250.0 COG0749@1|root,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,465DD@72275|Alteromonadaceae 1236|Gammaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity - - - - - - - - - - - - DNA_pol_A k59_16135_1 1229780.BN381_50110 8.59e-26 111.0 COG2255@1|root,COG2255@2|Bacteria,2GJZF@201174|Actinobacteria,3UWC6@52018|unclassified Actinobacteria (class) 201174|Actinobacteria L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N k59_53260_1 1234888.K0A2J2_9VIRU 3.93e-57 195.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_76485_1 563038.HMPREF0851_00147 3.06e-61 212.0 COG0308@1|root,COG0308@2|Bacteria,1TR43@1239|Firmicutes,4HA20@91061|Bacilli 91061|Bacilli E aminopeptidase pepN GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - ERAP1_C,Peptidase_M1 k59_655959_1 1379708.S5SYC3_9CIRC 3.88e-27 112.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_425732_1 469660.A8HP44_9CAUD 9.62e-65 199.0 4QCMM@10239|Viruses,4QUPN@35237|dsDNA viruses no RNA stage,4QRPI@28883|Caudovirales,4QP24@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_302420_1 272562.CA_C0062 1.77e-14 77.0 COG4722@1|root,COG4722@2|Bacteria,1V8VY@1239|Firmicutes,2494G@186801|Clostridia,36F4E@31979|Clostridiaceae 186801|Clostridia S tail component - - - - - - - - - - - - Sipho_tail k59_589200_1 1177181.T9A_00138 5.65e-18 80.1 COG0358@1|root,COG0358@2|Bacteria,1N364@1224|Proteobacteria,1SDEX@1236|Gammaproteobacteria 1236|Gammaproteobacteria L DNA primase - - - - - - - - - - - - zf-CHC2 k59_157731_1 1280679.ATVX01000013_gene2580 8.74e-09 59.7 COG2189@1|root,COG2189@2|Bacteria,1TR8A@1239|Firmicutes,249A1@186801|Clostridia,4BZX8@830|Butyrivibrio 186801|Clostridia L DNA methylase - - 2.1.1.72 ko:K00571,ko:K07316 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_449988_2 1692246.A0A0K1RLM8_9CIRC 6.55e-19 87.4 4QBFZ@10239|Viruses,4QUKU@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_450000_1 1201293.AKXQ01000022_gene442 2.79e-08 60.5 2FCN8@1|root,344RH@2|Bacteria,1P2BH@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_425751_1 1121360.AUAQ01000003_gene2057 3.78e-22 105.0 COG5412@1|root,COG5412@2|Bacteria,2IH91@201174|Actinobacteria 201174|Actinobacteria E phage tail tape measure protein - - - - - - - - - - - - - k59_425757_2 1379713.S5SYD9_9CIRC 6.01e-18 84.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_492116_5 105154.Q9MBU6_9VIRU 1.67e-221 630.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_246085_1 316407.85674960 3.65e-05 50.1 COG0675@1|root,COG0675@2|Bacteria,1MUU0@1224|Proteobacteria,1RS1J@1236|Gammaproteobacteria,3XPN5@561|Escherichia 1236|Gammaproteobacteria L Transposase Z012_11195 - - ko:K07496 - - - - ko00000 - - - HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon k59_41027_3 1088864.G8IEE0_9CAUD 2.63e-28 106.0 4QAQV@10239|Viruses,4QUPK@35237|dsDNA viruses no RNA stage,4QPCB@28883|Caudovirales 28883|Caudovirales S protein disulfide oxidoreductase activity - - - - - - - - - - - - - k59_328101_1 391165.GbCGDNIH1_1507 2.25e-32 126.0 COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,2TR3H@28211|Alphaproteobacteria,2JPAT@204441|Rhodospirillales 204441|Rhodospirillales M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C k59_266587_1 1121451.DESAM_22654 2.9e-24 111.0 COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,42QJ2@68525|delta/epsilon subdivisions,2WM78@28221|Deltaproteobacteria,2M8CT@213115|Desulfovibrionales 28221|Deltaproteobacteria S VWA-like domain (DUF2201) - - - - - - - - - - - - DUF2201,DUF2201_N k59_492144_1 1385658.U5KPZ6_9VIRU 2.44e-82 259.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_266591_4 1382304.JNIL01000001_gene1829 1.5e-30 130.0 COG2425@1|root,COG2425@2|Bacteria,1UZ1Z@1239|Firmicutes,4HCH8@91061|Bacilli 91061|Bacilli S von Willebrand factor (vWF) type A domain - - - - - - - - - - - - VWA_2,VWA_CoxE k59_41389_1 260827.Q6R6B4_9CAUD 2.75e-40 148.0 4QCM5@10239|Viruses,4QVZY@35237|dsDNA viruses no RNA stage,4QQFH@28883|Caudovirales,4QNDH@10744|Podoviridae 10744|Podoviridae S Bacteriophage head to tail connecting protein - GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019028,GO:0019058,GO:0019068,GO:0019072,GO:0019073,GO:0032991,GO:0044403,GO:0044419,GO:0044423,GO:0046798,GO:0051704 - - - - - - - - - - - k59_41389_2 439235.Dalk_3968 3.63e-16 82.4 COG5323@1|root,COG5323@2|Bacteria,1R049@1224|Proteobacteria,42UYF@68525|delta/epsilon subdivisions 1224|Proteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6 k59_82509_1 1121271.AUCM01000049_gene2545 4.38e-44 159.0 COG0270@1|root,COG0270@2|Bacteria,1NPQG@1224|Proteobacteria,2U226@28211|Alphaproteobacteria 28211|Alphaproteobacteria L C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_410666_2 1126411.I1TEL3_9CIRC 7.56e-37 141.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_20983_3 1618247.A0A0C5IMK7_9CIRC 2.87e-11 69.3 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_226003_6 1234888.K0A2J2_9VIRU 1.85e-112 344.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_537640_1 105154.Q9MBU6_9VIRU 1.5e-70 229.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_516974_1 1234888.K0A2J2_9VIRU 2.06e-46 167.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_167602_1 1555208.A0A097EW24_9CAUD 4.95e-07 53.1 4QAKM@10239|Viruses,4QPEF@28883|Caudovirales,4QKNE@10699|Siphoviridae 10699|Siphoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_167602_3 1325130.HFN_1892 3.88e-20 89.4 COG0500@1|root,COG0500@2|Bacteria,1QYFD@1224|Proteobacteria,42Y49@68525|delta/epsilon subdivisions,2YRNW@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria Q methyltransferase - - - - - - - - - - - - Methyltransf_2 k59_188158_10 864702.OsccyDRAFT_3629 2.91e-12 73.6 COG5545@1|root,COG5545@2|Bacteria,1G1ZC@1117|Cyanobacteria,1HATX@1150|Oscillatoriales 1117|Cyanobacteria S Virulence-associated protein E - - - - - - - - - - - - DUF3854,Prim-Pol,VirE k59_455250_1 864702.OsccyDRAFT_0687 2.11e-44 155.0 2CWXD@1|root,32T0J@2|Bacteria,1GAQJ@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - k59_455256_1 1120971.AUCA01000043_gene1177 4.06e-19 90.9 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,4H9Z7@91061|Bacilli,279M8@186823|Alicyclobacillaceae 91061|Bacilli L DNA polymerase A domain - - - - - - - - - - - - DNA_pol_A k59_3824_1 105154.Q9MBU6_9VIRU 8.08e-61 204.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_619077_1 1122931.AUAE01000034_gene2775 0.000197 49.7 COG1196@1|root,COG1196@2|Bacteria,4NF3E@976|Bacteroidetes,2FNYJ@200643|Bacteroidia,22YP9@171551|Porphyromonadaceae 976|Bacteroidetes D Psort location OuterMembrane, score - - - - - - - - - - - - - k59_332371_1 1540092.A0A0A0RSY9_9CAUD 2.47e-27 110.0 4QC2T@10239|Viruses,4QPRB@28883|Caudovirales,4QNKM@10744|Podoviridae 10744|Podoviridae S transferase activity, transferring alkyl or aryl (other than methyl) groups - - - - - - - - - - - - - k59_332371_6 1195073.I6WLM5_9CAUD 4.88e-43 150.0 4QBHW@10239|Viruses,4QW8N@35237|dsDNA viruses no RNA stage,4QTT7@28883|Caudovirales,4QNKM@10744|Podoviridae 10744|Podoviridae S transferase activity, transferring alkyl or aryl (other than methyl) groups - - - - - - - - - - - - - k59_517001_1 1609634.A0A0C5AFV4_9VIRU 6.21e-39 146.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_23849_1 5850.PKH_122030 6.72e-15 79.3 COG0648@1|root,KOG3997@2759|Eukaryota,3YBDG@5794|Apicomplexa,3KA46@422676|Aconoidasida,3YYT3@5819|Haemosporida 422676|Aconoidasida G Apurinic apyrimidinic endonuclease - GO:0000726,GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 4.2.99.18 ko:K10771 ko03410,map03410 M00296 - - ko00000,ko00001,ko00002,ko01000,ko03400 - - - AP_endonuc_2 k59_207748_1 637389.Acaty_c1001 3.58e-11 65.5 COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,1RMBB@1236|Gammaproteobacteria,2NCKN@225057|Acidithiobacillales 225057|Acidithiobacillales IQ KR domain fabG - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k59_310935_2 1038860.AXAP01000015_gene2006 9.66e-17 83.2 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,2U6BJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S TIGRFAM phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_68559_1 1692253.A0A0K1RLM4_9CIRC 6.58e-30 120.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_580953_1 391615.ABSJ01000042_gene2283 7.8e-10 63.9 COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,1RN8S@1236|Gammaproteobacteria,1J4VC@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria NU COG4972 Tfp pilus assembly protein, ATPase PilM pilM - - ko:K02662 - - - - ko00000,ko02035,ko02044 - - - PilM_2 k59_622671_2 1609634.A0A0C5AFV4_9VIRU 5.63e-101 314.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_458765_1 744979.R2A130_1861 5.1e-05 48.9 COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,2TS2G@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the 'phage' integrase family intB - - - - - - - - - - - Arm-DNA-bind_3,Phage_integrase k59_644982_1 1538804.A0A088F6T3_9CAUD 4.55e-62 216.0 4QAKM@10239|Viruses,4QPEF@28883|Caudovirales,4QKNE@10699|Siphoviridae 10699|Siphoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_90102_3 1331060.RLDS_16020 8.38e-25 105.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2TSDW@28211|Alphaproteobacteria,2K42P@204457|Sphingomonadales 204457|Sphingomonadales S Terminase - - - - - - - - - - - - Terminase_1 k59_542703_2 1264737.K9S139_9CAUD 2.21e-29 108.0 4QE7X@10239|Viruses,4QVF0@35237|dsDNA viruses no RNA stage,4QPUM@28883|Caudovirales,4QP17@10744|Podoviridae 10744|Podoviridae S Cytidine and deoxycytidylate deaminase zinc-binding region - - - - - - - - - - - - - k59_581617_1 472759.Nhal_0629 6.22e-108 323.0 COG0675@1|root,COG0675@2|Bacteria,1MUU0@1224|Proteobacteria,1RY56@1236|Gammaproteobacteria,1WYVN@135613|Chromatiales 135613|Chromatiales L TIGRFAM transposase, IS605 OrfB - - - ko:K07496 - - - - ko00000 - - - HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon k59_645937_2 1117943.SFHH103_01649 2.45e-11 71.6 2DQJ1@1|root,3376F@2|Bacteria,1RKWB@1224|Proteobacteria,2UA4H@28211|Alphaproteobacteria,4BE0C@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - Beta_helix,Pectate_lyase_3 k59_232369_1 942016.E9NIH3_9CAUD 2.95e-30 112.0 4QDJJ@10239|Viruses,4QYWQ@35237|dsDNA viruses no RNA stage,4QTQX@28883|Caudovirales,4QP11@10744|Podoviridae 10744|Podoviridae S magnesium ion binding - - - - - - - - - - - - - k59_69195_1 1233951.IO90_17965 6.04e-07 53.1 2FDWD@1|root,30047@2|Bacteria,4PGXS@976|Bacteroidetes,1IM89@117743|Flavobacteriia,3HIXR@358033|Chryseobacterium 976|Bacteroidetes - - - - - - - - - - - - - - - k59_623348_1 679192.HMPREF9013_1318 5.48e-30 121.0 28HHC@1|root,2Z7T2@2|Bacteria,1TR3B@1239|Firmicutes,3VQ9J@526524|Erysipelotrichia 526524|Erysipelotrichia S AAA domain - - - - - - - - - - - - AAA_24 k59_232381_2 1147141.H6WSJ8_9CAUD 6.75e-27 103.0 4QBPX@10239|Viruses,4QQFB@28883|Caudovirales,4QMNJ@10699|Siphoviridae 10699|Siphoviridae S Protein of unknown function (DUF3307) - - - - - - - - - - - - - k59_652189_2 279383.Q5DN86_9CAUD 6.3e-08 56.2 4QG7K@10239|Viruses,4QZQI@35237|dsDNA viruses no RNA stage,4QQZP@28883|Caudovirales,4QN68@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_12707_1 1234888.K0A2J2_9VIRU 1.5e-55 189.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_606328_1 637390.AFOH01000122_gene429 0.000121 43.1 COG4197@1|root,COG4197@2|Bacteria,1QDBG@1224|Proteobacteria,1T99E@1236|Gammaproteobacteria,2NE25@225057|Acidithiobacillales 225057|Acidithiobacillales K Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT - - - - - - - - - - - - YdaS_antitoxin k59_464025_1 1122176.KB903536_gene1787 3.34e-55 204.0 COG3209@1|root,COG4932@1|root,COG4935@1|root,COG3209@2|Bacteria,COG4932@2|Bacteria,COG4935@2|Bacteria,4PKBQ@976|Bacteroidetes,1IQYI@117747|Sphingobacteriia 976|Bacteroidetes M SprB repeat - - - - - - - - - - - - CHU_C,DUF11,SdrD_B,SprB k59_445529_2 10742.Q9MCV7_BPHK0 2.42e-22 99.0 4QBV3@10239|Viruses,4QW0W@35237|dsDNA viruses no RNA stage,4QPPJ@28883|Caudovirales,4QKW5@10699|Siphoviridae 10699|Siphoviridae S Phage Terminase - - - - - - - - - - - - - k59_503785_2 1379707.S5T672_9CIRC 1.46e-23 103.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_528262_1 198110.B3FJH9_9CAUD 1.77e-12 71.6 4QFGJ@10239|Viruses,4R0A2@35237|dsDNA viruses no RNA stage,4QTCF@28883|Caudovirales,4QIHG@10662|Myoviridae 10662|Myoviridae S tRNA guanylyltransferase activity - - - - - - - - - - - - - k59_111085_2 298386.PBPRB1277 6.67e-12 77.4 COG5281@1|root,COG5281@2|Bacteria,1QUCD@1224|Proteobacteria,1T1T2@1236|Gammaproteobacteria 1236|Gammaproteobacteria D tape measure protein - - - - - - - - - - - - Phage_HK97_TLTM,TMP_2,Tape_meas_lam_C k59_214413_1 585502.HMPREF0645_2609 1.21e-77 253.0 COG0553@1|root,COG0863@1|root,COG0553@2|Bacteria,COG0863@2|Bacteria,4NHHF@976|Bacteroidetes,2FRI5@200643|Bacteroidia 976|Bacteroidetes KL DNA methylase - - - - - - - - - - - - Helicase_C,N6_N4_Mtase,SNF2_N k59_214419_1 194867.ALBQ01000032_gene969 1.23e-21 95.5 COG0451@1|root,COG4641@1|root,COG0451@2|Bacteria,COG4641@2|Bacteria,1MXKV@1224|Proteobacteria,2TRM0@28211|Alphaproteobacteria,2K1V1@204457|Sphingomonadales 204457|Sphingomonadales GM GDP-mannose 4,6 dehydratase - - 4.1.1.35,5.1.3.2 ko:K01784,ko:K08678 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R01384,R02984 RC00289,RC00508 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd,Glyco_trans_1_2 k59_299235_3 428125.CLOLEP_01362 5.74e-21 92.0 2A0KC@1|root,30NQJ@2|Bacteria,1V3K4@1239|Firmicutes,24HYK@186801|Clostridia,3WN0E@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_548649_1 1556290.A0A0A0RQH0_9CAUD 1.09e-29 124.0 4QAK6@10239|Viruses,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_202012_2 381764.Fnod_0559 1.32e-09 59.3 COG0836@1|root,COG0836@2|Bacteria,2GCPW@200918|Thermotogae 200918|Thermotogae M PFAM Nucleotidyl transferase - - 2.7.7.13 ko:K00971 ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110 M00114,M00361,M00362 R00885 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase k59_219100_1 861208.AGROH133_06202 1.22e-24 102.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2TSDW@28211|Alphaproteobacteria,4BCQ8@82115|Rhizobiaceae 28211|Alphaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_264917_1 444876.E3SQN9_9CAUD 5.49e-16 86.3 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales 28883|Caudovirales S N-acetylmuramoyl-L-alanine amidase activity - GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019058,GO:0019062,GO:0022610,GO:0039638,GO:0044403,GO:0044406,GO:0044419,GO:0044423,GO:0044650,GO:0051704,GO:0098015,GO:0098024 - - - - - - - - - - - k59_159822_1 1692242.A0A0K1RL37_9CIRC 1.81e-19 90.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_202070_1 105154.Q9MBU6_9VIRU 2.89e-79 258.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_509173_1 1150864.MILUP08_40784 4.97e-63 200.0 COG0566@1|root,COG0566@2|Bacteria,2GM1A@201174|Actinobacteria,4DB7B@85008|Micromonosporales 201174|Actinobacteria J tRNA rRNA methyltransferase trmH - 2.1.1.34 ko:K00556 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase k59_304501_1 1197951.I6S6K3_9CAUD 1.08e-06 57.8 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales 28883|Caudovirales S N-acetylmuramoyl-L-alanine amidase activity - - - - - - - - - - - - - k59_510003_1 1090319.KE386571_gene341 1.73e-14 79.0 COG1388@1|root,COG4842@1|root,COG1388@2|Bacteria,COG4842@2|Bacteria,1PEC9@1224|Proteobacteria,2URJJ@28211|Alphaproteobacteria,2K7Z3@204457|Sphingomonadales 204457|Sphingomonadales M Lysin motif - - - - - - - - - - - - LysM k59_56300_1 314271.RB2654_05400 7e-37 135.0 COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,2TRHR@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the pirin family yhhW - - ko:K06911 - - - - ko00000 - - - Pirin,Pirin_C k59_388574_1 232721.Ajs_0930 7.24e-25 106.0 2E8E5@1|root,332SK@2|Bacteria,1QXJ1@1224|Proteobacteria,2VX3U@28216|Betaproteobacteria,4AFIH@80864|Comamonadaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_160799_1 411471.SUBVAR_05969 4.1e-15 74.3 COG0756@1|root,COG0756@2|Bacteria,1V6HX@1239|Firmicutes,24K3X@186801|Clostridia,3WK0P@541000|Ruminococcaceae 186801|Clostridia F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA dut - 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase k59_510013_1 649747.HMPREF0083_01012 6.51e-05 49.3 COG4695@1|root,COG4695@2|Bacteria,1TP8B@1239|Firmicutes,4HCI7@91061|Bacilli,26WHP@186822|Paenibacillaceae 91061|Bacilli S Phage portal protein - - - - - - - - - - - - Phage_portal k59_142857_1 1214065.BAGV01000099_gene2076 9.15e-36 134.0 COG3969@1|root,COG3969@2|Bacteria,1NBDM@1224|Proteobacteria,1RYRP@1236|Gammaproteobacteria 1236|Gammaproteobacteria S phosphoadenosine phosphosulfate ybdN - - - - - - - - - - - DUF3440,PAPS_reduct k59_142857_2 1214065.BAGV01000099_gene2075 6.38e-36 133.0 COG1475@1|root,COG1475@2|Bacteria,1R5VN@1224|Proteobacteria,1RZ7C@1236|Gammaproteobacteria 1236|Gammaproteobacteria K ParB-like nuclease domain ybdM - - - - - - - - - - - ParBc k59_202993_1 1502770.JQMG01000001_gene2158 3.86e-62 209.0 COG4643@1|root,COG4643@2|Bacteria,1R6M4@1224|Proteobacteria,2WIC2@28216|Betaproteobacteria 28216|Betaproteobacteria L Phage plasmid primase P4 family - - - - - - - - - - - - - k59_634422_1 1461579.CCNK01000031_gene1091 2.23e-29 114.0 COG3646@1|root,COG3646@2|Bacteria,1N86G@1224|Proteobacteria,1S8Y9@1236|Gammaproteobacteria,1Y871@135625|Pasteurellales 135625|Pasteurellales S Phage regulatory protein Rha (Phage_pRha) Z012_01170 - - - - - - - - - - - ORF11CD3,Phage_pRha k59_268181_2 90814.KL370891_gene1763 0.000639 45.1 COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,1RMQI@1236|Gammaproteobacteria,45ZT2@72273|Thiotrichales 72273|Thiotrichales K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth rpoD - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 k59_431789_1 948071.S4S2N2_9CAUD 1.14e-11 66.6 4QH10@10239|Viruses,4QVVN@35237|dsDNA viruses no RNA stage,4QSY9@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_637351_1 1234888.K0A2J2_9VIRU 1.55e-76 247.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_514437_1 1618237.A0A0C5IMG6_9CIRC 1.13e-22 99.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_534710_1 1203605.HMPREF1531_01505 7.53e-27 110.0 COG0526@1|root,COG0785@1|root,COG0526@2|Bacteria,COG0785@2|Bacteria,2HPPV@201174|Actinobacteria,4DVCD@85009|Propionibacteriales 201174|Actinobacteria O Cytochrome C biogenesis protein - - - - - - - - - - - - - k59_124269_1 2003327.CAPSD_BPCHP 2.43e-44 161.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_411471_1 222984.JNCS01000002_gene1065 5.69e-32 137.0 COG0417@1|root,COG1372@1|root,arCOG00328@2157|Archaea,arCOG03145@2157|Archaea,2XU1K@28890|Euryarchaeota,23RXE@183963|Halobacteria 183963|Halobacteria L COG0417 DNA polymerase elongation subunit (family B) polB1 - 2.7.7.7 ko:K02319 ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032 - - - DNA_pol_B,DNA_pol_B_exo1,Intein_splicing k59_268195_1 563192.HMPREF0179_01975 9.72e-79 251.0 COG3969@1|root,COG3969@2|Bacteria,1NBDM@1224|Proteobacteria,42YI7@68525|delta/epsilon subdivisions,2WTVR@28221|Deltaproteobacteria,2MAX0@213115|Desulfovibrionales 28221|Deltaproteobacteria S Domain of unknown function (DUF3440) - - - - - - - - - - - - DUF3440,PAPS_reduct k59_431815_1 1158292.JPOE01000002_gene2727 1.36e-56 192.0 COG0582@1|root,COG0582@2|Bacteria,1MWBN@1224|Proteobacteria,2VK8Q@28216|Betaproteobacteria,1KMNI@119065|unclassified Burkholderiales 28216|Betaproteobacteria L Phage integrase family - - - - - - - - - - - - Arm-DNA-bind_3,Phage_int_SAM_3,Phage_integrase k59_268200_1 319225.Plut_0088 7.65e-23 90.9 COG0724@1|root,COG0724@2|Bacteria,1FE64@1090|Chlorobi 1090|Chlorobi S PFAM RNP-1 like RNA-binding protein - - - - - - - - - - - - RRM_1 k59_268200_2 1304878.AUGD01000014_gene3052 7.17e-41 143.0 COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,2TRTZ@28211|Alphaproteobacteria,3JT22@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T transcriptional regulator, winged helix family copR - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C k59_124289_1 1005995.GTPT_1641 5.93e-08 57.4 2AC53@1|root,311PE@2|Bacteria,1REZC@1224|Proteobacteria,1S4EF@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_493582_2 253839.SSNG_02571 2.82e-08 64.3 2E9RT@1|root,32Y7C@2|Bacteria,2I89H@201174|Actinobacteria 201174|Actinobacteria S Siphovirus ReqiPepy6 Gp37-like protein - - - - - - - - - - - - Sipho_Gp37 k59_493582_16 1159870.KB907784_gene2419 1.23e-23 114.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2VJ57@28216|Betaproteobacteria,3T32Z@506|Alcaligenaceae 28216|Betaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_452739_1 575540.Isop_3669 3.06e-08 60.5 COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,2J1FN@203682|Planctomycetes 203682|Planctomycetes KL Belongs to the N(4) N(6)-methyltransferase family - - - - - - - - - - - - N6_N4_Mtase,ParBc k59_477124_3 511062.GU3_08615 4.5e-19 83.2 COG3108@1|root,COG3108@2|Bacteria,1N6F7@1224|Proteobacteria,1SBQ7@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Peptidase M15 - - - - - - - - - - - - Peptidase_M15_3 k59_393584_1 1250232.JQNJ01000001_gene3055 3.61e-05 52.8 COG3055@1|root,COG3291@1|root,COG3055@2|Bacteria,COG3291@2|Bacteria,4NHHD@976|Bacteroidetes,1HWPE@117743|Flavobacteriia 976|Bacteroidetes M Di-glucose binding within endoplasmic reticulum - - - - - - - - - - - - He_PIG,Kelch_1,Kelch_6,Malectin,PKD k59_86829_3 105154.Q9MBU6_9VIRU 1.16e-141 426.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_270623_3 1149133.ppKF707_0767 1.16e-09 65.5 COG5525@1|root,COG5525@2|Bacteria,1MVS3@1224|Proteobacteria,1RRH5@1236|Gammaproteobacteria,1YEHD@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Phage terminase large subunit (GpA) - - - - - - - - - - - - Terminase_GpA k59_578303_1 1278078.G419_20340 2.71e-13 72.4 COG3247@1|root,COG3247@2|Bacteria 2|Bacteria U response to pH - - - - - - - - - - - - DUF308 k59_4610_1 330214.NIDE3986 6.17e-09 62.4 COG4626@1|root,COG4626@2|Bacteria 2|Bacteria S Terminase - - - - - - - - - - - - Terminase_1 k59_517768_1 1234880.K0A2H8_9CIRC 6.37e-14 78.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_641737_1 1379717.S5SY19_9CIRC 1.77e-31 121.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_352476_1 323261.Noc_0401 8.88e-164 471.0 COG0675@1|root,COG0675@2|Bacteria,1MUU0@1224|Proteobacteria,1RY56@1236|Gammaproteobacteria,1WYVN@135613|Chromatiales 135613|Chromatiales L TIGRFAM transposase, IS605 OrfB - - - ko:K07496 - - - - ko00000 - - - HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon k59_127740_1 1234888.K0A2J2_9VIRU 3.79e-32 127.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_539005_1 1122176.KB903532_gene2460 7.05e-17 91.3 COG1028@1|root,COG1028@2|Bacteria,4NUJD@976|Bacteroidetes 976|Bacteroidetes IQ Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - - - - - - - - - - - k59_477899_1 1382306.JNIM01000001_gene1551 2.2e-18 86.7 COG0556@1|root,COG0556@2|Bacteria,2G5SU@200795|Chloroflexi 200795|Chloroflexi L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB - - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB k59_251254_1 1123072.AUDH01000038_gene151 6.75e-23 107.0 COG5281@1|root,COG5281@2|Bacteria,1MX2R@1224|Proteobacteria,2U3WK@28211|Alphaproteobacteria,2JTUX@204441|Rhodospirillales 204441|Rhodospirillales D tape measure protein - - - - - - - - - - - - - k59_271024_1 1122225.AULQ01000009_gene341 1.45e-29 125.0 2EAST@1|root,334US@2|Bacteria,4NRGD@976|Bacteroidetes,1I583@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_497078_1 1234888.K0A2J2_9VIRU 2.08e-50 177.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_5109_1 105154.Q9MBU6_9VIRU 3.61e-114 348.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_459712_1 105559.Nwat_1521 2.3e-153 445.0 COG0675@1|root,COG0675@2|Bacteria,1MUU0@1224|Proteobacteria,1RS1J@1236|Gammaproteobacteria,1X038@135613|Chromatiales 135613|Chromatiales L Probable transposase - - - ko:K07496 - - - - ko00000 - - - HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon k59_192532_1 1788444.A0A190WHB9_9CIRC 0.00081 48.5 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_192532_2 759938.F5BSB4_9CIRC 9.26e-32 128.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_482431_2 203275.BFO_0169 4.36e-50 175.0 COG1449@1|root,COG1449@2|Bacteria,4NFXW@976|Bacteroidetes,2FMRY@200643|Bacteroidia,22X3U@171551|Porphyromonadaceae 976|Bacteroidetes G Belongs to the glycosyl hydrolase 57 family amyA - 3.2.1.1 ko:K07405 ko00500,ko01100,map00500,map01100 - R02108,R02112,R11262 - ko00000,ko00001,ko01000 - GH57 - Glyco_hydro_57 k59_254562_1 1354303.M917_2306 8.05e-13 73.6 COG4695@1|root,COG4695@2|Bacteria,1MUP5@1224|Proteobacteria,1RPB0@1236|Gammaproteobacteria,3NMGT@468|Moraxellaceae 1236|Gammaproteobacteria S Phage portal protein - - - - - - - - - - - - Phage_portal k59_355228_1 1383055.S5Y190_9CAUD 9.42e-29 112.0 4QGJF@10239|Viruses,4QU68@28883|Caudovirales,4QMKG@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_582022_1 649639.Bcell_2721 6.57e-30 122.0 COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,1UHQM@1239|Firmicutes,4HGW7@91061|Bacilli,1ZBWW@1386|Bacillus 91061|Bacilli D phage tail tape measure protein - - - - - - - - - - - - Peptidase_M23,PhageMin_Tail,SLT k59_91467_1 867845.KI911784_gene676 2.21e-07 57.8 COG1559@1|root,COG1559@2|Bacteria,2G6G8@200795|Chloroflexi,375DA@32061|Chloroflexia 32061|Chloroflexia S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation mltG - - ko:K07082 - - - - ko00000 - - - YceG k59_254568_1 1234888.K0A2J2_9VIRU 2.26e-74 241.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_418136_1 281090.Lxx03850 2.58e-15 78.6 2AYW5@1|root,31R1R@2|Bacteria,2HT7A@201174|Actinobacteria,4FS92@85023|Microbacteriaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_397169_4 1540097.A0A0A0YW79_9CAUD 1.42e-30 123.0 4QBY0@10239|Viruses,4QQ4Q@28883|Caudovirales,4QNNN@10744|Podoviridae 10744|Podoviridae S UvrD-like helicase C-terminal domain - - - - - - - - - - - - - k59_582030_1 292414.TM1040_1679 7.03e-49 161.0 COG4725@1|root,COG4725@2|Bacteria,1R553@1224|Proteobacteria,2TRP6@28211|Alphaproteobacteria,4NDH5@97050|Ruegeria 28211|Alphaproteobacteria H MT-A70 - - - - - - - - - - - - MT-A70 k59_172870_1 1229172.JQFA01000002_gene4276 7.19e-27 111.0 COG0577@1|root,COG0577@2|Bacteria,1G1W4@1117|Cyanobacteria,1H89H@1150|Oscillatoriales 1117|Cyanobacteria V ABC-type antimicrobial peptide transport system, permease component salY - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k59_295175_2 1038860.AXAP01000015_gene2006 1.06e-30 123.0 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,2U6BJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S TIGRFAM phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_151219_1 1073754.G0ZNE5_9VIRU 2.93e-29 114.0 4QAIU@10239|Viruses 10239|Viruses S HNH endonuclease - - - - - - - - - - - - - k59_254585_1 1123511.KB905855_gene1994 1.47e-05 52.8 COG0749@1|root,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,4H1ZM@909932|Negativicutes 909932|Negativicutes L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A k59_459753_1 77586.LPERR08G14530.1 4.14e-16 84.3 COG0428@1|root,KOG2693@2759|Eukaryota,37N50@33090|Viridiplantae,3GBBF@35493|Streptophyta,3KPIY@4447|Liliopsida,3I370@38820|Poales 35493|Streptophyta P ZIP Zinc transporter - GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0006873,GO:0006875,GO:0006882,GO:0008150,GO:0008324,GO:0009987,GO:0012505,GO:0015075,GO:0015318,GO:0019725,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0034220,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0046873,GO:0046915,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055069,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0070838,GO:0071577,GO:0072503,GO:0072507,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:0098771 - ko:K14713 - - - - ko00000,ko02000 2.A.5.4.3,2.A.5.4.4,2.A.5.4.7 - - Zip k59_97511_1 1123508.JH636447_gene7991 2.19e-55 187.0 COG2401@1|root,COG2401@2|Bacteria,2IYZ0@203682|Planctomycetes 203682|Planctomycetes K acetyltransferase - - - - - - - - - - - - - k59_155138_1 1480731.X2KUJ0_9CAUD 1.01e-05 53.5 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_299498_1 945713.IALB_1498 8.23e-11 60.1 COG1983@1|root,COG1983@2|Bacteria 2|Bacteria KT positive regulation of macromolecule biosynthetic process pspC1 - - ko:K03973 - - - - ko00000,ko02048,ko03000 - - - PspC k59_565471_2 455632.SGR_3885 2.18e-19 90.1 COG1651@1|root,COG1651@2|Bacteria,2IGR9@201174|Actinobacteria,419IK@629295|Streptomyces griseus group 201174|Actinobacteria O DSBA-like thioredoxin domain - - - - - - - - - - - - Thioredoxin_4 k59_628055_1 1406785.U5PU90_9CAUD 1e-14 85.1 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales 28883|Caudovirales S N-acetylmuramoyl-L-alanine amidase activity - GO:0005575,GO:0019012,GO:0044423,GO:0098015,GO:0098025 - - - - - - - - - - - k59_358871_2 69328.PVLB_20830 1.09e-13 77.0 COG4695@1|root,COG4695@2|Bacteria,1MUP5@1224|Proteobacteria,1RPB0@1236|Gammaproteobacteria 1236|Gammaproteobacteria S portal protein - - - - - - - - - - - - Phage_portal k59_13451_1 643867.Ftrac_3133 2.27e-05 47.8 COG0805@1|root,COG0805@2|Bacteria,4NEKM@976|Bacteroidetes,47KG0@768503|Cytophagia 976|Bacteroidetes U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes tatC - - ko:K03118 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - TatC k59_359268_2 981335.G4W934_9CAUD 5.3e-44 153.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales 28883|Caudovirales S N-methyltransferase activity - - - - - - - - - - - - - k59_111693_1 1470593.BW43_03642 5.67e-42 146.0 COG0237@1|root,COG0237@2|Bacteria,1NEFS@1224|Proteobacteria 1224|Proteobacteria H dephospho-CoA kinase activity - - - - - - - - - - - - - k59_504494_1 1437882.AZRU01000008_gene2961 1.68e-26 107.0 COG4695@1|root,COG4695@2|Bacteria 2|Bacteria N Portal protein - - - - - - - - - - - - Collagen k59_401926_1 1123278.KB893581_gene1049 6.46e-05 47.8 292N1@1|root,2ZQ5X@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_382031_1 1238186.AOCN01000004_gene58 3.34e-11 66.2 2F7JH@1|root,34004@2|Bacteria,2INSW@201174|Actinobacteria,4FQ8A@85023|Microbacteriaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_628564_1 477184.KYC_19384 4.57e-12 68.2 COG3501@1|root,COG3501@2|Bacteria,1R540@1224|Proteobacteria,2VS00@28216|Betaproteobacteria 28216|Betaproteobacteria S Baseplate assembly protein - - - - - - - - - - - - - k59_592084_1 1250232.JQNJ01000001_gene2386 1.86e-06 59.7 COG1511@1|root,COG3210@1|root,COG5644@1|root,COG1511@2|Bacteria,COG3210@2|Bacteria,COG5644@2|Bacteria,4PKI0@976|Bacteroidetes,1HYWF@117743|Flavobacteriia 976|Bacteroidetes U PFAM Collagen triple helix repeat (20 copies) - - - - - - - - - - - - Collagen k59_184104_1 1041159.AZUW01000007_gene5298 4.64e-33 134.0 COG3378@1|root,COG3378@2|Bacteria,1R0JX@1224|Proteobacteria,2TYRR@28211|Alphaproteobacteria,4BHI9@82115|Rhizobiaceae 28211|Alphaproteobacteria S Phage plasmid primase P4 family - - - - - - - - - - - - - k59_202842_1 105154.Q9MBU6_9VIRU 3.09e-160 469.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_184127_1 494416.AYXN01000023_gene703 4.71e-09 63.2 COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,1RMNP@1236|Gammaproteobacteria,3NJI0@468|Moraxellaceae 1236|Gammaproteobacteria L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 k59_202851_1 1385658.U5KNR1_9VIRU 9.78e-40 143.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_202851_3 1385658.U5KPZ6_9VIRU 2.78e-229 649.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_471014_2 760192.Halhy_3005 1.01e-28 108.0 COG0629@1|root,COG0629@2|Bacteria,4PGRJ@976|Bacteroidetes,1IU5E@117747|Sphingobacteriia 976|Bacteroidetes L Domain of unknown function (DUF3127) - - - - - - - - - - - - DUF3127 k59_407449_1 140626.JHWB01000009_gene1075 1.76e-05 50.1 COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,2490S@186801|Clostridia 186801|Clostridia L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA - - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N k59_305342_1 1416011.V9QJ30_9CAUD 8.66e-13 69.3 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales,4QNBQ@10744|Podoviridae 10744|Podoviridae S HNH endonuclease - - - - - - - - - - - - - k59_20123_2 1498011.A0A096XUU0_9CAUD 6.03e-45 167.0 4QG38@10239|Viruses,4QQVI@28883|Caudovirales,4QNWM@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_596210_2 1239384.K4MPS9_9CAUD 7.92e-09 53.9 4QC2V@10239|Viruses,4QUQ5@35237|dsDNA viruses no RNA stage,4QPIC@28883|Caudovirales,4QNYP@10744|Podoviridae 10744|Podoviridae S Superinfection immunity protein - - - - - - - - - - - - - k59_432219_1 1038860.AXAP01000067_gene8427 4.6e-98 305.0 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,2U6BJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S TIGRFAM phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_411881_2 691965.D4P7D6_9CAUD 3.42e-147 445.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_22176_2 1618259.A0A0C5I2B5_9CIRC 2.56e-51 177.0 4QE84@10239|Viruses,4QUKR@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_350206_1 754059.M1PRW7_9CAUD 1.41e-33 140.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QNBD@10744|Podoviridae 10744|Podoviridae S outer membrane - - - - - - - - - - - - - k59_555445_1 691965.D4P7L7_9CAUD 1.2e-118 374.0 4QB9J@10239|Viruses,4QXFE@35237|dsDNA viruses no RNA stage,4QS1Z@28883|Caudovirales,4QN8F@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_555445_2 742740.HMPREF9474_02279 9.39e-78 237.0 29YRZ@1|root,30KMY@2|Bacteria,1V4Y4@1239|Firmicutes,24HPY@186801|Clostridia,221XY@1506553|Lachnoclostridium 186801|Clostridia S Protein of unknown function (DUF2800) - - - - - - - - - - - - DUF2800 k59_330260_2 216594.MMAR_3906 3.84e-17 81.6 COG2197@1|root,COG2197@2|Bacteria 2|Bacteria K response regulator - - - - - - - - - - - - HNH_3,Replicase k59_103921_1 1618260.A0A0C5I2C5_9CIRC 2.79e-79 245.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_596216_1 400668.Mmwyl1_4219 2.53e-25 109.0 COG1061@1|root,COG1061@2|Bacteria,1N52C@1224|Proteobacteria,1RSQN@1236|Gammaproteobacteria,1XJ09@135619|Oceanospirillales 135619|Oceanospirillales L Helicase conserved C-terminal domain - - - - - - - - - - - - Helicase_C,ResIII k59_227118_1 1788455.A0A190WHF5_9CIRC 5.31e-14 75.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_186778_2 1379720.S5TNF0_9CIRC 9.95e-17 85.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_330635_1 1452718.JBOY01000021_gene722 3.03e-23 100.0 COG0749@1|root,COG0749@2|Bacteria,1MWX7@1224|Proteobacteria,1S0Q1@1236|Gammaproteobacteria 1236|Gammaproteobacteria L ORF located using Glimmer RBSfinder - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A,DNA_pol_A_exo1 k59_638349_2 1121948.AUAC01000007_gene271 5.09e-06 54.7 COG1403@1|root,COG1403@2|Bacteria,1MWEQ@1224|Proteobacteria,2TR3M@28211|Alphaproteobacteria,43WS5@69657|Hyphomonadaceae 28211|Alphaproteobacteria L HNH endonuclease MA20_20605 - - - - - - - - - - - HNH,HNH_5 k59_42773_2 945083.E7EKU2_9CAUD 3.14e-07 52.8 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QKNE@10699|Siphoviridae 10699|Siphoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_576364_1 1437610.BREU_1261 6.98e-11 72.4 COG5412@1|root,COG5412@2|Bacteria,2IH91@201174|Actinobacteria 201174|Actinobacteria E phage tail tape measure protein - - - - - - - - - - - - - k59_125041_1 1147157.K7PJW8_9CAUD 5.86e-19 94.7 4QBV3@10239|Viruses,4QW0W@35237|dsDNA viruses no RNA stage,4QPPJ@28883|Caudovirales,4QKW5@10699|Siphoviridae 10699|Siphoviridae S Phage Terminase - - - - - - - - - - - - - k59_268852_1 472759.Nhal_3989 2.54e-17 84.7 28H9R@1|root,2Z7MD@2|Bacteria,1MVTR@1224|Proteobacteria,1RMPH@1236|Gammaproteobacteria,1X2QH@135613|Chromatiales 135613|Chromatiales S Domain of unknown function (DUF932) - - - - - - - - - - - - DUF932 k59_170221_1 742740.HMPREF9474_02276 1.57e-11 61.2 2BD7A@1|root,326VE@2|Bacteria,1USRB@1239|Firmicutes,25ASG@186801|Clostridia,223BG@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_170221_2 742733.HMPREF9469_05036 1.75e-44 149.0 2AIHK@1|root,318ZG@2|Bacteria,1V7P0@1239|Firmicutes,24KNU@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_170221_3 665950.HMPREF1025_01991 2.77e-37 131.0 2DHA9@1|root,32U8X@2|Bacteria,1VD44@1239|Firmicutes,24NC3@186801|Clostridia 186801|Clostridia S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - - k59_579592_1 309801.trd_1166 6.01e-56 189.0 COG0593@1|root,COG0593@2|Bacteria,2G5W8@200795|Chloroflexi,27XP6@189775|Thermomicrobia 189775|Thermomicrobia L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA - - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N k59_457818_1 1788454.A0A190WHE4_9CIRC 4.33e-54 184.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_45927_1 753085.F4YCV3_9CAUD 2.13e-09 57.8 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_45927_2 1121100.JCM6294_535 1.88e-179 519.0 COG0553@1|root,COG0863@1|root,COG0553@2|Bacteria,COG0863@2|Bacteria,4NHHF@976|Bacteroidetes,2FRI5@200643|Bacteroidia,4ATW7@815|Bacteroidaceae 976|Bacteroidetes KL DNA methylase - - - - - - - - - - - - Helicase_C,N6_N4_Mtase,SNF2_N k59_209648_2 105154.Q9MBU3_9VIRU 1.45e-11 68.9 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_498299_1 10752.Q8LTE3_BPN4 1.81e-09 60.5 4QBMV@10239|Viruses,4QUU6@35237|dsDNA viruses no RNA stage,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_252471_1 1385658.U5KPZ6_9VIRU 4.57e-162 473.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_252471_3 1165094.RINTHH_3920 1.92e-77 244.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_252471_4 1986029.Q9MBM6_9VIRU 2.82e-18 83.6 4QDBB@10239|Viruses,4QUM0@29258|ssDNA viruses,4QP4D@10841|Microviridae 10841|Microviridae S Chlamydia-phage Chp2 scaffold (Chlamy_scaf) - - - - - - - - - - - - - k59_252471_6 105154.Q9MBU6_9VIRU 6.19e-72 232.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_89046_2 105154.Q9MBU6_9VIRU 4.6e-134 407.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_6571_2 1037409.BJ6T_53040 3.77e-19 95.5 COG5565@1|root,COG5565@2|Bacteria,1RHD5@1224|Proteobacteria,2UB9H@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6 k59_353749_1 1168034.FH5T_07240 1.01e-07 62.0 COG4733@1|root,COG4733@2|Bacteria 2|Bacteria S cellulase activity - - 3.2.1.8 ko:K01181 - - - - ko00000,ko01000 - - - Big_2,CBM9_1,CBM_4_9,Cellulase,DUF285,Glyco_hydro_10,SLH,VCBS,fn3 k59_621632_1 1357400.HMPREF2086_01502 2.57e-65 211.0 COG0863@1|root,COG0863@2|Bacteria,1R7RV@1224|Proteobacteria,42NFT@68525|delta/epsilon subdivisions 1224|Proteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.113 ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_457859_2 553220.CAMGR0001_2769 7.48e-11 67.4 COG4675@1|root,COG4675@2|Bacteria,1N0FZ@1224|Proteobacteria,42TXS@68525|delta/epsilon subdivisions 1224|Proteobacteria S Phage Tail Collar Domain - - - - - - - - - - - - Collar k59_316815_1 765911.Thivi_4612 1.36e-72 233.0 COG1241@1|root,COG1241@2|Bacteria,1R189@1224|Proteobacteria,1S5IK@1236|Gammaproteobacteria,1WYBT@135613|Chromatiales 135613|Chromatiales L DNA replication initiation - - - - - - - - - - - - - k59_94979_1 1609634.A0A0C5ANA6_9VIRU 1.49e-14 77.0 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_235140_1 1126411.I1TEL3_9CIRC 2.4e-27 110.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_650113_1 138119.DSY0542 3.05e-05 56.6 COG2247@1|root,COG4932@1|root,COG2247@2|Bacteria,COG4932@2|Bacteria,1UIDD@1239|Firmicutes,25EIH@186801|Clostridia,264RK@186807|Peptococcaceae 186801|Clostridia M Fibronectin type 3 domain - - - - - - - - - - - - CW_binding_2,fn3 k59_379600_1 1122201.AUAZ01000017_gene2962 2.89e-07 60.5 COG4675@1|root,COG4675@2|Bacteria 2|Bacteria M tail collar domain protein - - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - Collar,Phage_fiber_2 k59_485795_2 880073.Calab_1470 1.54e-46 156.0 COG0270@1|root,COG0270@2|Bacteria 2|Bacteria L DNA (cytosine-5-)-methyltransferase activity dcm - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_316846_2 997346.HMPREF9374_0456 1.77e-28 109.0 COG0302@1|root,COG0302@2|Bacteria,1TRNM@1239|Firmicutes,4HAXS@91061|Bacilli,27B0B@186824|Thermoactinomycetaceae 91061|Bacilli H GTP cyclohydrolase I folE GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydroI k59_650135_1 419665.Maeo_0791 4.68e-13 76.3 COG0085@1|root,arCOG01762@2157|Archaea,2XU9Q@28890|Euryarchaeota,23Q3N@183939|Methanococci 183939|Methanococci K Belongs to the RNA polymerase beta chain family rpoB2 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03045 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00184 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3 k59_379608_1 1634486.A0A0E3M1X5_9VIRU 3.4e-34 127.0 4QB6C@10239|Viruses 10239|Viruses L Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_584459_2 1235801.C822_01135 8.91e-31 120.0 COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,4H9YT@91061|Bacilli,3F3RQ@33958|Lactobacillaceae 91061|Bacilli F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - - Adenylsucc_synt k59_444223_2 644968.DFW101_3503 1.31e-41 160.0 COG4695@1|root,COG4695@2|Bacteria,1MUP5@1224|Proteobacteria,42MDD@68525|delta/epsilon subdivisions,2WU18@28221|Deltaproteobacteria,2MACT@213115|Desulfovibrionales 28221|Deltaproteobacteria S portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_462840_1 649747.HMPREF0083_01048 2.82e-21 104.0 COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,4H9Y8@91061|Bacilli,26R5G@186822|Paenibacillaceae 91061|Bacilli L Participates in initiation and elongation during chromosome replication - - - - - - - - - - - - DnaB,DnaB_C k59_462840_3 294631.Q5ZGB2_9CAUD 0.000828 43.5 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_584939_2 1123250.KB908384_gene1351 6.02e-10 60.1 COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,4H206@909932|Negativicutes 909932|Negativicutes L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_235641_1 1234888.K0A2J2_9VIRU 2.48e-46 166.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_298185_1 1173025.GEI7407_1420 2.64e-14 73.9 COG3108@1|root,COG3108@2|Bacteria,1GQNJ@1117|Cyanobacteria,1H8ID@1150|Oscillatoriales 1117|Cyanobacteria S Peptidase M15 - - - - - - - - - - - - Peptidase_M15_3 k59_182692_2 1234888.K0A2J2_9VIRU 1.09e-46 164.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_141173_12 1124849.G9IAC1_9CAUD 3.89e-06 51.2 4QAIK@10239|Viruses,4QUPH@35237|dsDNA viruses no RNA stage,4QPEB@28883|Caudovirales 28883|Caudovirales S phosphoprotein phosphatase activity - - - - - - - - - - - - - k59_201285_1 29760.VIT_14s0036g00990.t01 9.43e-24 99.0 COG5272@1|root,KOG0001@2759|Eukaryota,37K87@33090|Viridiplantae,3G7XW@35493|Streptophyta 35493|Streptophyta O Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked - GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0019538,GO:0019941,GO:0030163,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0071704,GO:1901564,GO:1901565,GO:1901575 - ko:K08770 ko03320,map03320 - - - ko00000,ko00001,ko04121 - - - ubiquitin k59_54593_1 1234888.K0A2J2_9VIRU 4.85e-89 280.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_264183_1 322710.Avin_05900 2.95e-124 364.0 COG0675@1|root,COG0675@2|Bacteria,1MUU0@1224|Proteobacteria,1RS1J@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Transposase gipA - - ko:K07496 - - - - ko00000 - - - HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon k59_36768_1 652103.Rpdx1_2983 8.04e-27 105.0 COG2197@1|root,COG2197@2|Bacteria,1NA3X@1224|Proteobacteria,2UHEF@28211|Alphaproteobacteria 28211|Alphaproteobacteria KT HNH endonuclease - - - - - - - - - - - - HNH_3 k59_590519_1 391009.Tmel_1446 5.25e-18 95.1 COG3500@1|root,COG4733@1|root,COG3500@2|Bacteria,COG4733@2|Bacteria,2GDX2@200918|Thermotogae 200918|Thermotogae S Fibronectin type 3 domain - - - - - - - - - - - - - k59_77994_1 221915.Q6Y7T9_BPPGK 5.28e-35 129.0 4QBHW@10239|Viruses,4QVHG@35237|dsDNA viruses no RNA stage,4QTT7@28883|Caudovirales,4QJZQ@10662|Myoviridae 10662|Myoviridae S sequence-specific DNA binding transcription factor activity - - - - - - - - - - - - - k59_362367_2 398525.KB900701_gene5079 1.96e-05 48.1 COG0791@1|root,COG0791@2|Bacteria,1N732@1224|Proteobacteria,2UH6X@28211|Alphaproteobacteria,3K18Y@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M NlpC/P60 family - - - - - - - - - - - - NLPC_P60 k59_182766_1 525904.Tter_0176 6.39e-35 133.0 COG0143@1|root,COG0143@2|Bacteria,2NNTX@2323|unclassified Bacteria 2|Bacteria J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g,tRNA_bind k59_469361_1 1234888.K0A2J2_9VIRU 1.96e-70 231.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_386599_1 356851.JOAN01000021_gene2365 5.46e-05 51.6 COG0553@1|root,COG0553@2|Bacteria,2GNS0@201174|Actinobacteria 201174|Actinobacteria L SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,SNF2_N k59_386599_5 526218.Sterm_2019 2.02e-22 113.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,378G8@32066|Fusobacteria 32066|Fusobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,HHH_5 k59_386599_6 1255043.TVNIR_1739 2.95e-51 184.0 COG1652@1|root,COG3023@1|root,COG3179@1|root,COG1652@2|Bacteria,COG3023@2|Bacteria,COG3179@2|Bacteria,1R71F@1224|Proteobacteria,1RZTY@1236|Gammaproteobacteria,1WZ8I@135613|Chromatiales 135613|Chromatiales V Chitinase class I - - - - - - - - - - - - Glyco_hydro_19 k59_386599_7 1123277.KB893184_gene3959 4.31e-10 66.2 COG0847@1|root,COG0847@2|Bacteria,4NE82@976|Bacteroidetes,47N5P@768503|Cytophagia 976|Bacteroidetes L DNA polymerase III dnaQ - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T k59_386599_9 1395983.A0A067Y1K5_9CAUD 3.85e-18 85.1 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales,4QNBQ@10744|Podoviridae 10744|Podoviridae S HNH endonuclease - - - - - - - - - - - - - k59_386599_11 861452.HMPREF9093_02214 3.02e-09 60.5 COG0419@1|root,COG0419@2|Bacteria,3797C@32066|Fusobacteria 32066|Fusobacteria L AAA domain - - - ko:K03546 - - - - ko00000,ko03400 - - - AAA_15,AAA_23 k59_508500_1 176652.VF244_IIV6 4.38e-22 98.6 4QAIK@10239|Viruses,4QUPH@35237|dsDNA viruses no RNA stage 10239|Viruses S bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity - - - - - - - - - - - - - k59_17795_1 247490.KSU1_C1664 2.05e-58 204.0 COG3387@1|root,COG3387@2|Bacteria,2J1PN@203682|Planctomycetes 203682|Planctomycetes G Glycosyl hydrolases family 15 - - 3.2.1.3 ko:K01178 ko00500,ko01100,map00500,map01100 - R01790,R01791,R06199 - ko00000,ko00001,ko01000 - GH15 - Glyco_hydro_15 k59_362389_1 504832.OCAR_6140 6.91e-05 47.4 28JTG@1|root,2Z9IR@2|Bacteria,1R0GC@1224|Proteobacteria,2TURR@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF2793) - - - - - - - - - - - - DUF2793 k59_36792_3 1416009.V9VG06_9CAUD 9.65e-70 228.0 4QAR1@10239|Viruses,4QUNA@35237|dsDNA viruses no RNA stage,4QPJE@28883|Caudovirales,4QNDS@10744|Podoviridae 10744|Podoviridae S ATPase activity - - - - - - - - - - - - - k59_36792_4 1540097.A0A0A0YU59_9CAUD 4.01e-79 254.0 4QB3X@10239|Viruses,4QPEE@28883|Caudovirales,4QNCI@10744|Podoviridae 10744|Podoviridae S VWA-like domain (DUF2201) - - - - - - - - - - - - - k59_636874_1 1132026.I6NQ46_9CAUD 1.89e-07 62.4 4QBSJ@10239|Viruses,4QXH4@35237|dsDNA viruses no RNA stage,4QPFJ@28883|Caudovirales,4QKUK@10699|Siphoviridae 10699|Siphoviridae S DNA primase activity - - - - - - - - - - - - - k59_205549_1 1692256.A0A0K1RL85_9CIRC 4.9e-20 88.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_205549_2 1692242.A0A0K1RKZ2_9CIRC 1.83e-28 114.0 4QFEW@10239|Viruses,4QUKZ@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_329307_1 1204521.I7A8M7_9CAUD 1.03e-99 324.0 4QCZC@10239|Viruses,4QX3V@35237|dsDNA viruses no RNA stage,4QRH3@28883|Caudovirales,4QHVR@10662|Myoviridae 10662|Myoviridae S Bacterial DNA polymerase III alpha subunit - - - - - - - - - - - - - k59_329307_2 1460634.JCM19037_221 3.73e-07 58.2 COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,4H9RF@91061|Bacilli 91061|Bacilli L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity polC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.7 ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon k59_472922_1 553204.CORAM0001_0889 8.59e-06 47.0 COG0756@1|root,COG0756@2|Bacteria,2IHYY@201174|Actinobacteria,22N78@1653|Corynebacteriaceae 201174|Actinobacteria F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA dut - 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase k59_472922_5 1392498.JQLH01000001_gene3001 1.28e-08 59.7 COG0494@1|root,COG0494@2|Bacteria,4PKI3@976|Bacteroidetes,1IJ9T@117743|Flavobacteriia,2PGDJ@252356|Maribacter 976|Bacteroidetes L NUDIX domain - - - - - - - - - - - - NUDIX k59_267977_2 109760.SPPG_05489T0 8.9e-09 67.0 2CMGD@1|root,2QQ9V@2759|Eukaryota,39B3J@33154|Opisthokonta 33154|Opisthokonta - - - - - - - - - - - - - - DNA_pol_B_2,Rho_N k59_103461_1 269796.Rru_A2664 2.17e-50 175.0 COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,2TSI0@28211|Alphaproteobacteria,2JQSR@204441|Rhodospirillales 204441|Rhodospirillales K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA - 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L k59_103461_2 598659.NAMH_1694 1.3e-06 48.5 COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,42SBD@68525|delta/epsilon subdivisions,2YPKU@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria J ribosomal protein L17 rplQ - - ko:K02879 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L17 k59_616634_2 637389.Acaty_c0848 8.4e-07 49.3 2CIZN@1|root,33BAP@2|Bacteria,1NJHF@1224|Proteobacteria,1SJH5@1236|Gammaproteobacteria,2NDBN@225057|Acidithiobacillales 225057|Acidithiobacillales S Superinfection immunity protein - - - - - - - - - - - - Imm_superinfect k59_493499_1 1385658.U5KPZ6_9VIRU 1.05e-100 313.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_205708_1 1788455.A0A190WHF5_9CIRC 9.12e-31 124.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_83414_3 1618248.A0A0C5IB82_9CIRC 1.79e-21 94.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_534496_1 935840.JAEQ01000007_gene3957 1.21e-33 133.0 COG3740@1|root,COG3740@2|Bacteria,1QVIJ@1224|Proteobacteria,2TVIM@28211|Alphaproteobacteria,43N07@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Caudovirus prohead serine protease - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_288207_2 1505225.A0A068CBG2_9CAUD 2.33e-32 123.0 4QBHW@10239|Viruses,4QTT7@28883|Caudovirales,4QJZQ@10662|Myoviridae 10662|Myoviridae S sequence-specific DNA binding transcription factor activity - - - - - - - - - - - - - k59_288209_1 1173762.S4TP25_9CAUD 9.1e-31 126.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_226602_1 1219031.BBJR01000049_gene1546 3.66e-25 101.0 2CIEP@1|root,315ZW@2|Bacteria,1NVZS@1224|Proteobacteria,2W2U4@28216|Betaproteobacteria,4AHV4@80864|Comamonadaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_554995_1 1618248.A0A0C5IB82_9CIRC 1.26e-61 205.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_452510_1 948870.J3JSC0_9CAUD 1.1e-07 52.4 4QBY1@10239|Viruses,4QZSN@35237|dsDNA viruses no RNA stage,4QS4Q@28883|Caudovirales,4QK9A@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_45464_2 1538804.A0A088FAL2_9CAUD 1.1e-49 163.0 4QBB2@10239|Viruses,4QRAZ@28883|Caudovirales,4QKR3@10699|Siphoviridae 10699|Siphoviridae S 6-pyruvoyl tetrahydropterin synthase - - - - - - - - - - - - - k59_45488_1 1173762.S4TP25_9CAUD 8.21e-45 163.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_5965_1 95619.PM1_0217520 5.34e-19 85.5 COG2197@1|root,COG2197@2|Bacteria,1NA3X@1224|Proteobacteria 1224|Proteobacteria KT HNH endonuclease - - - - - - - - - - - - HNH_3 k59_437510_2 428125.CLOLEP_01413 2.77e-29 108.0 2E2Y0@1|root,32XYV@2|Bacteria,1VD9S@1239|Firmicutes,24PK0@186801|Clostridia,3WPDR@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_437510_3 665956.HMPREF1032_00678 1.23e-26 101.0 2E6F6@1|root,3312K@2|Bacteria,1VFHE@1239|Firmicutes,24SVA@186801|Clostridia,3WPKU@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_437510_4 742740.HMPREF9474_02267 4.29e-85 259.0 28NM4@1|root,2ZBMQ@2|Bacteria,1V1QD@1239|Firmicutes,24G1B@186801|Clostridia,221N8@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_437510_5 411460.RUMTOR_01339 1.54e-47 160.0 2CGG9@1|root,2ZVSJ@2|Bacteria,1V633@1239|Firmicutes,24HD0@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_437510_6 411460.RUMTOR_01342 1.02e-33 129.0 28NM4@1|root,2ZBMQ@2|Bacteria,1V1QD@1239|Firmicutes,24G1B@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_497841_2 1177928.TH2_10614 1.54e-05 53.5 COG1100@1|root,COG1100@2|Bacteria,1N5QS@1224|Proteobacteria,2TSKW@28211|Alphaproteobacteria,2JVNE@204441|Rhodospirillales 204441|Rhodospirillales S AAA domain - - - - - - - - - - - - AAA_24 k59_497841_6 86106.I862_04365 1.77e-14 75.9 28J3M@1|root,2Z8ZT@2|Bacteria,1Q2A4@1224|Proteobacteria,2TSHZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - PDDEXK_1 k59_353636_1 41875.XP_007508914.1 9.51e-17 85.9 COG0553@1|root,KOG0384@2759|Eukaryota,389PT@33090|Viridiplantae 33090|Viridiplantae K SNF2 family N-terminal domain - - 3.6.4.12 ko:K14436 - - - - ko00000,ko01000,ko03036 - - - Chromo,FYRC,FYRN,Helicase_C,SNF2_N k59_498215_1 1007105.PT7_P068 1.38e-32 128.0 2DXNB@1|root,345PI@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_479781_1 1330700.JQNC01000003_gene755 3.28e-18 82.4 COG1694@1|root,COG1694@2|Bacteria,1WK7E@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S PFAM MazG nucleotide pyrophosphohydrolase - - - - - - - - - - - - MazG k59_420793_2 1038860.AXAP01000067_gene8427 2.08e-23 104.0 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,2U6BJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S TIGRFAM phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_486538_2 1123487.KB892865_gene1372 8.1e-29 110.0 2ECIJ@1|root,336GQ@2|Bacteria,1NFBI@1224|Proteobacteria,2VYFZ@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_444328_1 264462.Bd2548 2.68e-07 58.5 COG0729@1|root,COG2911@1|root,COG0729@2|Bacteria,COG2911@2|Bacteria,1N928@1224|Proteobacteria 1224|Proteobacteria M Chaperone of endosialidase - - - - - - - - - - - - Peptidase_S74 k59_547373_1 1348908.KI518589_gene2548 1.06e-64 218.0 COG3378@1|root,COG3378@2|Bacteria,1TQP9@1239|Firmicutes,4HA5U@91061|Bacilli,1ZQE6@1386|Bacillus 91061|Bacilli S Phage plasmid primase, P4 family - - - ko:K06919 - - - - ko00000 - - - D5_N,Pox_D5 k59_298243_1 172088.AUGA01000071_gene7569 8.96e-69 228.0 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,2U6BJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S TIGRFAM phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_400184_1 1429794.A0A0A0Q3J1_9CAUD 1.97e-09 62.8 4QAKE@10239|Viruses,4QUP7@35237|dsDNA viruses no RNA stage,4QPCE@28883|Caudovirales,4QI56@10662|Myoviridae 10662|Myoviridae S nucleic acid binding - - - - - - - - - - - - - k59_357796_1 1278971.AOGF01000034_gene1771 1.04e-08 58.2 2CDFK@1|root,2Z8BH@2|Bacteria,1R6SX@1224|Proteobacteria,1RZJS@1236|Gammaproteobacteria,1Y88G@135625|Pasteurellales 135625|Pasteurellales S DNA N-6-adenine-methyltransferase (Dam) - - - - - - - - - - - - Dam k59_502878_1 744980.TRICHSKD4_2427 0.00088 47.0 COG4733@1|root,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria,2TV2W@28211|Alphaproteobacteria 28211|Alphaproteobacteria S COG4733 Phage-related protein, tail component - - - - - - - - - - - - Phage-tail_3 k59_650938_1 400668.Mmwyl1_1424 4.97e-15 79.7 COG0591@1|root,COG0784@1|root,COG4191@1|root,COG0591@2|Bacteria,COG0784@2|Bacteria,COG4191@2|Bacteria,1QTSW@1224|Proteobacteria,1T1G2@1236|Gammaproteobacteria,1XH3H@135619|Oceanospirillales 135619|Oceanospirillales T COG0591 Na proline symporter - - - - - - - - - - - - HATPase_c,HisKA,PAS_4,PAS_7,Response_reg,SSF k59_547394_1 1117943.SFHH103_03053 1.27e-19 87.8 29YD9@1|root,30K7Q@2|Bacteria,1Q0E3@1224|Proteobacteria,2V1AY@28211|Alphaproteobacteria,4BHJW@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_650959_4 450851.PHZ_c2212 2.33e-39 155.0 COG5323@1|root,COG5323@2|Bacteria,1R0EP@1224|Proteobacteria,2TYQ7@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - - k59_564334_1 1449347.JQLN01000004_gene7007 1.4e-27 113.0 COG5323@1|root,COG5323@2|Bacteria,2I1XF@201174|Actinobacteria,2M5NQ@2063|Kitasatospora 201174|Actinobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6 k59_95951_1 105154.Q9MBU6_9VIRU 9.5e-90 281.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_95951_2 1609634.A0A0C5ANA6_9VIRU 3.91e-05 51.6 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_95951_4 105154.Q9MBU0_9VIRU 1.83e-59 201.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_95951_6 1385658.U5KPZ6_9VIRU 1.63e-119 362.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_564345_1 1416009.V9VEJ1_9CAUD 5.76e-28 118.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_11728_3 1235798.C817_05404 1.47e-08 55.5 28NEI@1|root,2ZBH3@2|Bacteria,1U6F4@1239|Firmicutes,24GVI@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_200848_1 1540097.A0A0A0YW88_9CAUD 1.22e-52 186.0 4QGA5@10239|Viruses,4QT9N@28883|Caudovirales,4QP47@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_507917_1 1234888.K0A2J2_9VIRU 1.03e-13 75.9 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_36358_1 1458669.W6AQY0_9CAUD 1.23e-07 58.5 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - GO:0008150,GO:0044403,GO:0044409,GO:0044411,GO:0044419,GO:0051701,GO:0051704,GO:0051828,GO:0051830,GO:0085027 - - - - - - - - - - - k59_240560_3 1203550.HMPREF1475_00629 1.31e-17 85.9 COG2189@1|root,COG2189@2|Bacteria,4NHTG@976|Bacteroidetes,2FPXQ@200643|Bacteroidia 976|Bacteroidetes L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.72 ko:K00571,ko:K07319 - - - - ko00000,ko01000,ko02048 - - - MerR,N6_N4_Mtase k59_140884_3 221359.RS9916_36792 2.27e-39 154.0 COG2931@1|root,COG2982@1|root,COG5563@1|root,COG2931@2|Bacteria,COG2982@2|Bacteria,COG5563@2|Bacteria,1G2XZ@1117|Cyanobacteria,1H051@1129|Synechococcus 1117|Cyanobacteria Q repeat protein - - - - - - - - - - - - Big_3_3,DUF4347,FG-GAP_2,VCBS k59_54328_1 1336208.JADY01000006_gene611 4.08e-10 68.2 COG4695@1|root,COG4695@2|Bacteria,1MUP5@1224|Proteobacteria,2TT33@28211|Alphaproteobacteria 28211|Alphaproteobacteria S portal protein - - - - - - - - - - - - Phage_portal k59_303484_1 1073754.G0ZNE5_9VIRU 1.07e-27 110.0 4QAIU@10239|Viruses 10239|Viruses S HNH endonuclease - - - - - - - - - - - - - k59_140886_2 742767.HMPREF9456_02044 2.9e-38 138.0 2CWXD@1|root,32T0J@2|Bacteria,4P63N@976|Bacteroidetes,2FYM4@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_240570_2 1469607.KK073768_gene2405 2.13e-06 50.8 COG1403@1|root,COG1403@2|Bacteria,1G2XW@1117|Cyanobacteria,1HQGV@1161|Nostocales 1117|Cyanobacteria V RRXRR protein - - - - - - - - - - - - HNH,HNH_5,RRXRR k59_264686_1 873513.HMPREF6485_2449 1.98e-15 76.6 COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes,2FNDJ@200643|Bacteroidia 976|Bacteroidetes E Asparagine synthase, glutamine-hydrolyzing asnB - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 k59_264686_2 439375.Oant_1510 4.5e-29 115.0 COG0270@1|root,COG0270@2|Bacteria,1MV9H@1224|Proteobacteria,2VAY6@28211|Alphaproteobacteria,1J477@118882|Brucellaceae 28211|Alphaproteobacteria L C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_18306_2 1327970.R9ZYA0_9CAUD 6.78e-21 92.4 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales,4QKM7@10699|Siphoviridae 10699|Siphoviridae S HNH endonuclease - - - - - - - - - - - - - k59_18306_3 1131812.JQMS01000001_gene52 4.05e-10 59.7 2AA6Y@1|root,30ZG0@2|Bacteria,4PDQN@976|Bacteroidetes,1INJM@117743|Flavobacteriia,2NZVB@237|Flavobacterium 976|Bacteroidetes - - - - - - - - - - - - - - - k59_141748_1 556269.ACDQ01000003_gene1356 1.19e-27 129.0 COG4733@1|root,COG4733@2|Bacteria,1PG9M@1224|Proteobacteria,2W1MG@28216|Betaproteobacteria,4782D@75682|Oxalobacteraceae 28216|Betaproteobacteria S cellulase activity - - - - - - - - - - - - - k59_574671_1 1201293.AKXQ01000022_gene442 4.17e-33 130.0 2FCN8@1|root,344RH@2|Bacteria,1P2BH@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_328544_1 641526.ADIWIN_3678 3.32e-15 80.1 COG0729@1|root,COG5295@1|root,COG0729@2|Bacteria,COG5295@2|Bacteria,4NJTK@976|Bacteroidetes,1HZNB@117743|Flavobacteriia 976|Bacteroidetes UW surface antigen - - - - - - - - - - - - Peptidase_S74 k59_533535_1 691965.D4P7C0_9CAUD 6.35e-28 104.0 4QDUR@10239|Viruses,4QVMY@35237|dsDNA viruses no RNA stage,4QU8R@28883|Caudovirales,4QKNQ@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_533535_3 691965.D4P7C3_9CAUD 4.36e-45 149.0 4QDCX@10239|Viruses,4R0GS@35237|dsDNA viruses no RNA stage,4QS3P@28883|Caudovirales,4QKU8@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_533535_4 742740.HMPREF9474_02273 1.46e-07 54.7 2EAAT@1|root,334F2@2|Bacteria,1VJJI@1239|Firmicutes,24TQU@186801|Clostridia,223KD@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_533535_5 691965.D4P7C5_9CAUD 0.0 933.0 4QBV3@10239|Viruses,4QW0W@35237|dsDNA viruses no RNA stage,4QPPJ@28883|Caudovirales,4QKW5@10699|Siphoviridae 10699|Siphoviridae S Phage Terminase - - - - - - - - - - - - - k59_533535_6 691965.D4P7D3_9CAUD 4.04e-168 485.0 4QAYV@10239|Viruses,4QUZ7@35237|dsDNA viruses no RNA stage,4QPU3@28883|Caudovirales,4QKKX@10699|Siphoviridae 10699|Siphoviridae S Phage portal protein - - - - - - - - - - - - - k59_533535_7 691965.D4P7D6_9CAUD 1.39e-199 585.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_410823_9 1411685.U062_02146 0.000621 43.9 2DGI2@1|root,2ZW2M@2|Bacteria,1P4XI@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_533837_2 279006.Q6J2M7_9CAUD 7.24e-06 53.5 4QAKE@10239|Viruses,4QUP7@35237|dsDNA viruses no RNA stage,4QPCE@28883|Caudovirales,4QI56@10662|Myoviridae 10662|Myoviridae S nucleic acid binding - - - - - - - - - - - - - k59_267377_1 1540098.A0A0A0RQI2_9CAUD 1.53e-116 365.0 4QB5I@10239|Viruses,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_41575_1 1692242.A0A0K1RKZ2_9CIRC 6.79e-31 120.0 4QFEW@10239|Viruses,4QUKZ@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_41575_2 1618248.A0A0C5IB82_9CIRC 3.82e-88 272.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_328929_2 417280.A1YZY9_9CAUD 2.37e-34 129.0 4QCW5@10239|Viruses,4QWI1@35237|dsDNA viruses no RNA stage,4QQVP@28883|Caudovirales,4QHUS@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_226234_1 880073.Calab_1470 3.03e-37 135.0 COG0270@1|root,COG0270@2|Bacteria 2|Bacteria L DNA (cytosine-5-)-methyltransferase activity dcm - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_328938_1 691965.D4P7D6_9CAUD 4.2e-53 187.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_123630_2 1486472.A0A068F4N3_9CAUD 3.8e-26 107.0 4QB8Y@10239|Viruses,4QRW4@28883|Caudovirales,4QMEY@10699|Siphoviridae 10699|Siphoviridae S nuclease activity - - - - - - - - - - - - - k59_185314_1 1123248.KB893316_gene4591 2.39e-10 60.1 COG0566@1|root,COG0566@2|Bacteria,4NM8C@976|Bacteroidetes,1IS2Z@117747|Sphingobacteriia 976|Bacteroidetes J SpoU rRNA Methylase family spoU - - - - - - - - - - - SpoU_methylase k59_23448_2 1562701.BBOF01000001_gene1844 2.17e-08 61.6 2F8II@1|root,340XB@2|Bacteria,1N0UB@1224|Proteobacteria,2WIF4@28216|Betaproteobacteria,1K8ZD@119060|Burkholderiaceae 1224|Proteobacteria S Carbohydrate binding domain - - - - - - - - - - - - - k59_516352_6 402777.KB235904_gene4460 4.4e-27 125.0 COG1028@1|root,COG1028@2|Bacteria,1G2IN@1117|Cyanobacteria,1H8RG@1150|Oscillatoriales 1117|Cyanobacteria IQ Short-chain dehydrogenase reductase Sdr - - - - - - - - - - - - - k59_413133_3 1556290.A0A0A0RSX5_9CAUD 2.75e-69 220.0 4QCAU@10239|Viruses,4QPJ6@28883|Caudovirales,4QKZJ@10699|Siphoviridae 10699|Siphoviridae S Pfam:GP88 - - - - - - - - - - - - - k59_23460_1 1380346.JNIH01000014_gene845 4.23e-10 66.6 COG3598@1|root,COG3598@2|Bacteria,2H0QU@201174|Actinobacteria 201174|Actinobacteria L Bifunctional DNA primase/polymerase, N-terminal - - - - - - - - - - - - Prim-Pol k59_167117_1 142661.REP_CACV 2.1e-142 410.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_537039_1 520709.F985_01890 2.66e-06 50.4 COG0270@1|root,COG0270@2|Bacteria,1N0XD@1224|Proteobacteria,1T05A@1236|Gammaproteobacteria 1236|Gammaproteobacteria L C-5 cytosine-specific DNA methylase - - - - - - - - - - - - DNA_methylase k59_577288_5 387631.Asulf_00521 9.9e-07 60.8 COG3979@1|root,COG5306@1|root,arCOG02420@1|root,arCOG03511@1|root,arCOG03553@1|root,arCOG09173@1|root,arCOG02420@2157|Archaea,arCOG03508@2157|Archaea,arCOG03511@2157|Archaea,arCOG03553@2157|Archaea,arCOG07581@2157|Archaea,arCOG09173@2157|Archaea 2157|Archaea C PKD domain containing protein - - - - - - - - - - - - CARDB,DUF2341,PKD,Pilin_N,S_layer_C k59_372359_1 1344012.ATMI01000056_gene1749 9.37e-05 50.1 2DNU8@1|root,32Z5M@2|Bacteria,1RGT6@1224|Proteobacteria,1S5HA@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - Peptidase_S74 k59_23753_1 1051675.G0YQJ1_9CAUD 4.28e-45 155.0 4QGM6@10239|Viruses,4QYNV@35237|dsDNA viruses no RNA stage,4QRH4@28883|Caudovirales,4QP0P@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_372360_3 338963.Pcar_1758 2.04e-17 85.5 COG1215@1|root,COG1215@2|Bacteria,1RJNP@1224|Proteobacteria,42ST7@68525|delta/epsilon subdivisions,2X7KP@28221|Deltaproteobacteria,43V18@69541|Desulfuromonadales 28221|Deltaproteobacteria H Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 k59_269910_1 105154.Q9MBU0_9VIRU 7.07e-35 135.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_269910_3 1609634.A0A0C5AFV4_9VIRU 1.63e-43 156.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_167503_1 148960.XP_006959034.1 4.08e-19 97.1 COG3579@1|root,KOG4128@2759|Eukaryota,38E6A@33154|Opisthokonta,3NVD9@4751|Fungi,3UZ1X@5204|Basidiomycota 4751|Fungi E bleomycin hydrolase LAP3 GO:0000096,GO:0000098,GO:0000122,GO:0000976,GO:0000977,GO:0000978,GO:0000987,GO:0001012,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003723,GO:0003729,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006355,GO:0006357,GO:0006508,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0009056,GO:0009063,GO:0009636,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016054,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042221,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043418,GO:0043436,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046395,GO:0046677,GO:0048519,GO:0048523,GO:0050667,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0097159,GO:0140096,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.22.40 ko:K01372 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C1_2 k59_249993_2 1385658.U5KNR1_9VIRU 1.43e-47 167.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_516831_2 1589297.A0A0B5H2N3_9CAUD 7.79e-84 257.0 4QEMD@10239|Viruses,4QUGF@28883|Caudovirales,4QNXF@10744|Podoviridae 10744|Podoviridae S AAA domain - - - - - - - - - - - - - k59_455150_1 105154.Q9MBU0_9VIRU 1.11e-26 114.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_540926_1 417280.A1YZY4_9CAUD 3.54e-75 248.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QI9F@10662|Myoviridae 10662|Myoviridae S Type III restriction enzyme, res subunit - - - - - - - - - - - - - k59_312814_5 478749.BRYFOR_08531 8.57e-18 79.7 2CGGA@1|root,345NF@2|Bacteria,1VZU0@1239|Firmicutes,253ZW@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_312814_6 691965.D4P7C0_9CAUD 4.61e-57 181.0 4QDUR@10239|Viruses,4QVMY@35237|dsDNA viruses no RNA stage,4QU8R@28883|Caudovirales,4QKNQ@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_312814_7 428125.CLOLEP_01407 2.55e-32 117.0 2DHA9@1|root,32U8X@2|Bacteria,1VD44@1239|Firmicutes,24NC3@186801|Clostridia,3WP9P@541000|Ruminococcaceae 186801|Clostridia S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - - k59_312814_8 658401.C7F4B3_9CAUD 4.67e-10 67.8 4QGP7@10239|Viruses,4QWWZ@35237|dsDNA viruses no RNA stage,4QQ0Q@28883|Caudovirales,4QMNP@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_621790_1 397945.Aave_1768 1.49e-47 172.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2VNHP@28216|Betaproteobacteria,4AC68@80864|Comamonadaceae 28216|Betaproteobacteria S Terminase - - - - - - - - - - - - Terminase_1 k59_353891_2 1237149.C900_05366 3.4e-07 58.2 COG3740@1|root,COG3740@2|Bacteria,4NDXV@976|Bacteroidetes,47V54@768503|Cytophagia 976|Bacteroidetes S Phage prohead protease, HK97 family - - - - - - - - - - - - Peptidase_S78 k59_231010_1 56780.SYN_02966 1.99e-75 247.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,42MW3@68525|delta/epsilon subdivisions,2WJRZ@28221|Deltaproteobacteria 28221|Deltaproteobacteria G Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate ppsA - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N k59_46057_4 264462.Bd1130 7.19e-07 62.0 COG3209@1|root,COG3209@2|Bacteria,1QY1R@1224|Proteobacteria,43C93@68525|delta/epsilon subdivisions,2MUT2@213481|Bdellovibrionales,2X7JI@28221|Deltaproteobacteria 213481|Bdellovibrionales M cell wall surface anchor family protein - - - - - - - - - - - - Peptidase_S74 k59_498419_1 755731.Clo1100_2169 1.99e-32 124.0 2CWXD@1|root,32T0J@2|Bacteria,1VCVP@1239|Firmicutes,24MPK@186801|Clostridia,36KI7@31979|Clostridiaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_129553_1 869209.Tresu_1582 1.75e-12 72.4 COG1198@1|root,COG1198@2|Bacteria,2J5B4@203691|Spirochaetes 203691|Spirochaetes L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA - - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII k59_580212_1 759362.KVU_1125 6.03e-07 54.3 COG1403@1|root,COG1403@2|Bacteria,1MWEQ@1224|Proteobacteria,2TR3M@28211|Alphaproteobacteria 28211|Alphaproteobacteria L HNH endonuclease MA20_20605 - - - - - - - - - - - HNH,HNH_5 k59_395476_2 1234888.K0A2J2_9VIRU 1.07e-19 88.2 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_438274_3 1235800.C819_00843 1.79e-20 97.1 COG0739@1|root,COG0791@1|root,COG0739@2|Bacteria,COG0791@2|Bacteria,1TP24@1239|Firmicutes,247K5@186801|Clostridia,27J83@186928|unclassified Lachnospiraceae 186801|Clostridia M NlpC p60 family protein - - - - - - - - - - - - NLPC_P60,Peptidase_M23 k59_26420_1 935948.KE386495_gene1203 3.33e-25 111.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,42HQD@68295|Thermoanaerobacterales 186801|Clostridia KL SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,SNF2_N k59_600801_1 105154.Q9MBU6_9VIRU 1.1e-202 583.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_600801_3 105154.Q9MBU0_9VIRU 9.82e-40 150.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_600801_6 105154.Q9MBU3_9VIRU 1.11e-06 54.3 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_375425_1 1327982.S0A1X8_9CAUD 1.52e-94 293.0 4QAYV@10239|Viruses 10239|Viruses S Phage portal protein - - - - - - - - - - - - - k59_335782_1 556269.ACDQ01000003_gene1356 9.98e-52 187.0 COG4733@1|root,COG4733@2|Bacteria,1PG9M@1224|Proteobacteria,2W1MG@28216|Betaproteobacteria,4782D@75682|Oxalobacteraceae 28216|Betaproteobacteria S cellulase activity - - - - - - - - - - - - - k59_149688_2 925409.KI911562_gene2008 2.25e-22 95.9 COG4627@1|root,COG4627@2|Bacteria 2|Bacteria - - - - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - Glycos_transf_2,Methyltransf_11,Methyltransf_23 k59_375439_2 864702.OsccyDRAFT_0687 3.49e-58 189.0 2CWXD@1|root,32T0J@2|Bacteria,1GAQJ@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - k59_560007_1 1448860.BBJO01000012_gene955 5.36e-11 73.6 arCOG02542@1|root,arCOG07554@1|root,arCOG02542@2157|Archaea,arCOG07554@2157|Archaea,2Y82Y@28890|Euryarchaeota,24140@183963|Halobacteria 183963|Halobacteria S The GLUG motif - - - - - - - - - - - - Glug k59_545527_1 693272.E3T4Z4_CROVB 1.76e-34 135.0 4QDEE@10239|Viruses,4QXW5@35237|dsDNA viruses no RNA stage 10239|Viruses L RNA polymerase beta subunit - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_297091_1 1121930.AQXG01000001_gene1548 6.41e-14 78.6 COG5164@1|root,COG5164@2|Bacteria,4NT5R@976|Bacteroidetes,1ISIJ@117747|Sphingobacteriia 976|Bacteroidetes K regulation of DNA-templated transcription, elongation - - - - - - - - - - - - LRR_5 k59_109542_1 552396.HMPREF0863_00318 3.71e-18 90.9 COG5281@1|root,COG5281@2|Bacteria,1TPWF@1239|Firmicutes 1239|Firmicutes M tape measure - - - - - - - - - - - - - k59_420021_1 1234888.K0A2J2_9VIRU 1.2e-24 107.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_420480_1 1172188.KB911820_gene2847 2.03e-17 80.9 COG3567@1|root,COG3567@2|Bacteria,2H48H@201174|Actinobacteria 201174|Actinobacteria S Phage portal protein, SPP1 Gp6-like - - - - - - - - - - - - Phage_prot_Gp6 k59_525949_2 1460634.JCM19037_4377 1.17e-18 84.0 2DQBA@1|root,335SB@2|Bacteria,1VHD4@1239|Firmicutes,4HPCE@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k59_133911_2 1121459.AQXE01000004_gene1690 1.56e-14 78.6 COG5323@1|root,COG5323@2|Bacteria,1R049@1224|Proteobacteria,42UYF@68525|delta/epsilon subdivisions,2WQN3@28221|Deltaproteobacteria,2M90K@213115|Desulfovibrionales 28221|Deltaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6 k59_626009_1 1203606.HMPREF1526_00223 1.25e-08 57.0 2EUAJ@1|root,33MSZ@2|Bacteria,1VP1P@1239|Firmicutes,24X0X@186801|Clostridia,36TTH@31979|Clostridiaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_626009_2 926562.Oweho_3332 1.61e-25 102.0 COG2003@1|root,COG2003@2|Bacteria,4NFBF@976|Bacteroidetes,1HXJ3@117743|Flavobacteriia,2PAQH@246874|Cryomorphaceae 976|Bacteroidetes L RadC-like JAB domain radC - - ko:K03630 - - - - ko00000 - - - RadC k59_297542_1 1449351.RISW2_21770 2.19e-09 68.9 COG1196@1|root,COG3941@1|root,COG1196@2|Bacteria,COG3941@2|Bacteria 2|Bacteria O tape measure - - - - - - - - - - - - PhageMin_Tail,TMP_2,Tape_meas_lam_C k59_485516_1 1169161.KB897755_gene6991 4.78e-07 51.6 COG0739@1|root,COG0739@2|Bacteria,2I4NQ@201174|Actinobacteria 201174|Actinobacteria M Peptidase family M23 - - - - - - - - - - - - Peptidase_M23,SLT k59_30232_1 290512.Paes_0835 1.35e-64 220.0 COG1226@1|root,COG4651@1|root,COG1226@2|Bacteria,COG4651@2|Bacteria,1FENU@1090|Chlorobi 1090|Chlorobi P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family - - - - - - - - - - - - Na_H_Exchanger,TrkA_N k59_10798_2 279303.Q6J817_9CAUD 1.28e-55 197.0 4QG9U@10239|Viruses,4R0A6@35237|dsDNA viruses no RNA stage,4QSKC@28883|Caudovirales,4QM4R@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_649869_1 1788455.A0A190WHF5_9CIRC 2.13e-68 220.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_553332_1 1234888.K0A2R8_9VIRU 3.34e-25 104.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_609714_2 1414738.V5UNX0_9CAUD 7.87e-05 45.4 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales,4QNBQ@10744|Podoviridae 10744|Podoviridae S HNH endonuclease - - - - - - - - - - - - - k59_655921_1 1692249.A0A0K1RLN8_9CIRC 9.19e-31 120.0 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_157614_1 1123073.KB899242_gene894 2.43e-15 80.1 COG1387@1|root,COG1387@2|Bacteria,1MYXV@1224|Proteobacteria,1RXT9@1236|Gammaproteobacteria,1X4PW@135614|Xanthomonadales 135614|Xanthomonadales L DNA polymerase beta thumb - - - - - - - - - - - - DNA_pol_B_thumb,HHH_5,HHH_8,PHP k59_16101_1 768710.DesyoDRAFT_5203 2.73e-15 82.4 COG5281@1|root,COG5281@2|Bacteria,1TPWF@1239|Firmicutes,24A8R@186801|Clostridia,265B7@186807|Peptococcaceae 186801|Clostridia S tape measure - - - - - - - - - - - - - k59_655944_1 1692242.A0A0K1RL37_9CIRC 9.46e-17 85.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_239500_1 1406780.U5PW18_9CAUD 1.02e-43 162.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_35825_1 865938.Weevi_0254 3.46e-29 117.0 COG1783@1|root,COG1783@2|Bacteria,4P9P0@976|Bacteroidetes,1I733@117743|Flavobacteriia 976|Bacteroidetes S Phage terminase large subunit - - - ko:K06909 - - - - ko00000 - - - Terminase_3 k59_35825_2 1229205.BUPH_04460 1.43e-06 48.9 COG0494@1|root,COG0494@2|Bacteria,1N317@1224|Proteobacteria,2WGF0@28216|Betaproteobacteria,1KDCF@119060|Burkholderiaceae 28216|Betaproteobacteria L nUDIX hydrolase - - - - - - - - - - - - DUF4406 k59_114858_2 1028806.GGE_2172 2.51e-28 121.0 COG1196@1|root,COG5281@1|root,COG1196@2|Bacteria,COG5281@2|Bacteria,1MX2R@1224|Proteobacteria,1SYI1@1236|Gammaproteobacteria 1236|Gammaproteobacteria D tape measure protein - - - - - - - - - - - - Phage_HK97_TLTM k59_240125_1 1316932.MHH_c16870 3.17e-16 81.6 COG0640@1|root,COG0640@2|Bacteria,1R194@1224|Proteobacteria,1T4WW@1236|Gammaproteobacteria,1Y94K@135625|Pasteurellales 135625|Pasteurellales K Helix-turn-helix domain - - - - - - - - - - - - HTH_36 k59_610344_3 1121926.AXWO01000003_gene732 2.55e-05 52.0 COG0322@1|root,COG0847@1|root,COG0322@2|Bacteria,COG0847@2|Bacteria,2GMC0@201174|Actinobacteria,4EXSP@85014|Glycomycetales 201174|Actinobacteria L GIY-YIG type nucleases (URI domain) dnaQ GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - GIY-YIG,RNase_T,UVR k59_610344_4 1204521.I7A8M7_9CAUD 2.53e-200 614.0 4QCZC@10239|Viruses,4QX3V@35237|dsDNA viruses no RNA stage,4QRH3@28883|Caudovirales,4QHVR@10662|Myoviridae 10662|Myoviridae S Bacterial DNA polymerase III alpha subunit - - - - - - - - - - - - - k59_610344_6 417280.A1YZY4_9CAUD 5.5e-117 360.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QI9F@10662|Myoviridae 10662|Myoviridae S Type III restriction enzyme, res subunit - - - - - - - - - - - - - k59_225151_2 1235659.S4T8U3_9CAUD 8.62e-24 99.0 4QAQV@10239|Viruses,4QUPK@35237|dsDNA viruses no RNA stage,4QPCB@28883|Caudovirales,4QHX6@10662|Myoviridae 10662|Myoviridae S hydrolase activity - - - - - - - - - - - - - k59_369011_1 1986029.Q9MBM3_9VIRU 1.17e-36 140.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_225171_1 563192.HMPREF0179_02963 1.01e-09 65.9 COG1196@1|root,COG3941@1|root,COG1196@2|Bacteria,COG3941@2|Bacteria 2|Bacteria O tape measure - - - ko:K03529 - - - - ko00000,ko03036 - - - PhageMin_Tail,Tape_meas_lam_C k59_369034_6 411460.RUMTOR_01348 7.58e-181 518.0 28J3N@1|root,2Z8ZU@2|Bacteria,1V15Z@1239|Firmicutes,249Z0@186801|Clostridia 186801|Clostridia S Phage portal protein - - - - - - - - - - - - Phage_portal k59_225224_1 1268068.PG5_22070 7.02e-11 67.8 COG3209@1|root,COG3209@2|Bacteria,1QVEQ@1224|Proteobacteria,1SGCM@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Chaperone of endosialidase - - - - - - - - - - - - Peptidase_S74 k59_225237_2 1347342.BN863_4870 3e-23 95.9 COG0357@1|root,COG0357@2|Bacteria,4NEJG@976|Bacteroidetes,1HYFU@117743|Flavobacteriia 976|Bacteroidetes J Specifically methylates the N7 position of a guanine in 16S rRNA rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 - - - - ko00000,ko01000,ko03009,ko03036 - - - GidB k59_122780_2 691965.D4P7D3_9CAUD 1.67e-17 83.6 4QAYV@10239|Viruses,4QUZ7@35237|dsDNA viruses no RNA stage,4QPU3@28883|Caudovirales,4QKKX@10699|Siphoviridae 10699|Siphoviridae S Phage portal protein - - - - - - - - - - - - - k59_60876_1 105154.Q9MBU6_9VIRU 3.62e-103 319.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_122874_1 1005994.GTGU_00289 2.69e-09 61.2 2DR9Y@1|root,33AUY@2|Bacteria,1NAA8@1224|Proteobacteria,1SDFU@1236|Gammaproteobacteria 1236|Gammaproteobacteria L NUMOD4 motif - - - - - - - - - - - - HNH_3,NUMOD4 k59_122887_1 1540098.A0A0A0RW10_9CAUD 7.76e-25 104.0 4QB40@10239|Viruses,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_122888_1 1229276.DI53_1323 1.06e-39 138.0 COG0720@1|root,COG0720@2|Bacteria,4NM8H@976|Bacteroidetes 976|Bacteroidetes H 6-pyruvoyl tetrahydropterin synthase queD - 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 - - - PTPS k59_122888_2 1538804.A0A088F7Y4_9CAUD 2.25e-96 293.0 4QH75@10239|Viruses,4QQZ4@28883|Caudovirales,4QKSF@10699|Siphoviridae 10699|Siphoviridae S GTP cyclohydrolase I activity - - - - - - - - - - - - - k59_122888_3 1175654.A0A0S0MVN0_9CAUD 3.31e-115 342.0 4QFED@10239|Viruses,4R072@35237|dsDNA viruses no RNA stage,4QPEH@28883|Caudovirales,4QN2V@10699|Siphoviridae 10699|Siphoviridae S tRNA modification - - - - - - - - - - - - - k59_122888_4 1538804.A0A088FAQ9_9CAUD 4.19e-101 306.0 4QFYS@10239|Viruses,4QUD0@28883|Caudovirales,4QMR9@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_122888_5 1538804.A0A088F6T3_9CAUD 1.55e-279 788.0 4QAKM@10239|Viruses,4QPEF@28883|Caudovirales,4QKNE@10699|Siphoviridae 10699|Siphoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_225467_1 1122182.KB903813_gene2836 5.76e-05 49.3 COG4570@1|root,COG4570@2|Bacteria,2GV9V@201174|Actinobacteria 201174|Actinobacteria L Endodeoxyribonuclease RusA - - - - - - - - - - - - RusA k59_61010_1 1227454.C446_09043 2.51e-13 79.0 arCOG01243@1|root,arCOG01243@2157|Archaea,2XTGZ@28890|Euryarchaeota,23SPG@183963|Halobacteria 183963|Halobacteria L integrase family - - - - - - - - - - - - Phage_integrase k59_225495_1 563192.HMPREF0179_02963 1.53e-13 80.1 COG1196@1|root,COG3941@1|root,COG1196@2|Bacteria,COG3941@2|Bacteria 2|Bacteria O tape measure - - - ko:K03529 - - - - ko00000,ko03036 - - - PhageMin_Tail,Tape_meas_lam_C k59_227723_2 69328.PVLB_20830 9.22e-16 83.6 COG4695@1|root,COG4695@2|Bacteria,1MUP5@1224|Proteobacteria,1RPB0@1236|Gammaproteobacteria 1236|Gammaproteobacteria S portal protein - - - - - - - - - - - - Phage_portal k59_125303_2 765911.Thivi_3515 1.79e-09 56.6 COG3772@1|root,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,1S99W@1236|Gammaproteobacteria 1236|Gammaproteobacteria G lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_392158_2 1379707.S5T672_9CIRC 2.32e-36 138.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_331001_1 1403819.BATR01000046_gene1343 1.03e-44 170.0 COG3941@1|root,COG3941@2|Bacteria,46Z3Y@74201|Verrucomicrobia,2IWBM@203494|Verrucomicrobiae 203494|Verrucomicrobiae S tape measure - - - - - - - - - - - - - k59_474681_1 145579.REP_BPPHM 6.94e-09 59.7 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_474681_3 2003327.CAPSD_BPCHP 1.45e-73 251.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_227729_1 1120936.KB907208_gene1069 7.88e-67 215.0 COG3567@1|root,COG3567@2|Bacteria,2H48H@201174|Actinobacteria 201174|Actinobacteria S Phage portal protein, SPP1 Gp6-like - - - - - - - - - - - - Phage_prot_Gp6 k59_618160_1 1609634.A0A0C5AFV4_9VIRU 2.02e-19 92.8 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_350839_1 1165094.RINTHH_3920 4.76e-39 142.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_516048_1 1385658.U5KPZ6_9VIRU 1.57e-51 179.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_536391_1 1122201.AUAZ01000017_gene2947 1.06e-59 208.0 COG0749@1|root,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,465DD@72275|Alteromonadaceae 1236|Gammaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity - - - - - - - - - - - - DNA_pol_A k59_331304_1 1385658.U5KNR1_9VIRU 3.88e-37 136.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_556243_1 1476390.A0A060RJ50_9CAUD 6.03e-24 112.0 4QBSJ@10239|Viruses,4QXH4@35237|dsDNA viruses no RNA stage,4QPFJ@28883|Caudovirales,4QKUK@10699|Siphoviridae 10699|Siphoviridae S DNA primase activity - - - - - - - - - - - - - k59_2872_3 1498011.A0A096XUV3_9CAUD 1.02e-55 183.0 4QAUS@10239|Viruses,4QQ2S@28883|Caudovirales 28883|Caudovirales S flavin adenine dinucleotide binding - - - - - - - - - - - - - k59_331306_1 1692242.A0A0K1RL37_9CIRC 1.14e-41 147.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_639009_1 1229780.BN381_430072 8.59e-218 674.0 COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,3UWBK@52018|unclassified Actinobacteria (class) 201174|Actinobacteria L DNA polymerase alpha chain like domain dnaE GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k59_639009_2 59374.Fisuc_2373 1.72e-58 199.0 COG0468@1|root,COG0468@2|Bacteria 2|Bacteria L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA k59_334664_1 7460.GB45451-PA 8.18e-05 50.4 COG0666@1|root,KOG0504@2759|Eukaryota,3A0WN@33154|Opisthokonta,3BPHY@33208|Metazoa,3CY26@33213|Bilateria,420BY@6656|Arthropoda,3SP2Y@50557|Insecta,46JII@7399|Hymenoptera 33208|Metazoa S Ankyrin repeats (3 copies) ASZ1 GO:0000003,GO:0000280,GO:0003006,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0006139,GO:0006259,GO:0006304,GO:0006305,GO:0006306,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007140,GO:0007276,GO:0007281,GO:0007283,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016070,GO:0019953,GO:0022402,GO:0022412,GO:0022414,GO:0030154,GO:0032259,GO:0032501,GO:0032502,GO:0032504,GO:0032991,GO:0034587,GO:0034641,GO:0034660,GO:0035770,GO:0036464,GO:0043046,GO:0043170,GO:0043186,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044703,GO:0044728,GO:0045495,GO:0046483,GO:0048232,GO:0048285,GO:0048468,GO:0048609,GO:0048856,GO:0048869,GO:0051321,GO:0051704,GO:0060293,GO:0071546,GO:0071704,GO:0071840,GO:0090304,GO:0140013,GO:1901360,GO:1903046,GO:1990904 - ko:K18410 - - - - ko00000,ko03036 - - - Ank_2,Ank_3,Ank_4,SAM_1,SAM_2 k59_45317_1 1449347.JQLN01000004_gene7007 1.23e-60 203.0 COG5323@1|root,COG5323@2|Bacteria,2I1XF@201174|Actinobacteria,2M5NQ@2063|Kitasatospora 201174|Actinobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6 k59_457483_6 1296660.S5MA26_9CAUD 2.02e-10 62.8 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QI9F@10662|Myoviridae 10662|Myoviridae S Type III restriction enzyme, res subunit - - - - - - - - - - - - - k59_540242_1 1323663.AROI01000009_gene3839 6.26e-24 110.0 2CERA@1|root,33EN3@2|Bacteria,1NPCT@1224|Proteobacteria,1SITV@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_519777_2 428125.CLOLEP_01398 3.46e-35 122.0 2CGGB@1|root,32UNH@2|Bacteria,1VD9W@1239|Firmicutes,24MWC@186801|Clostridia,3WPKG@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_479376_1 326424.FRAAL6628 5.12e-16 86.3 COG1361@1|root,COG3468@1|root,COG4719@1|root,COG1361@2|Bacteria,COG3468@2|Bacteria,COG4719@2|Bacteria,2I8F1@201174|Actinobacteria 201174|Actinobacteria M cellulase activity - - - - - - - - - - - - DUF11,He_PIG,fn3 k59_579601_2 1227352.C173_08376 5.59e-14 72.8 COG0463@1|root,COG0463@2|Bacteria,1TY2D@1239|Firmicutes,4I75G@91061|Bacilli,26W1J@186822|Paenibacillaceae 91061|Bacilli M Glycosyl transferase, family 2 - - - - - - - - - - - - Glyco_tranf_2_4 k59_170274_1 691965.D4P7L6_9CAUD 1.87e-65 206.0 4QFKG@10239|Viruses,4QV77@35237|dsDNA viruses no RNA stage,4QR6Q@28883|Caudovirales,4QMGT@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_170274_2 691965.D4P7L7_9CAUD 2.94e-26 110.0 4QB9J@10239|Viruses,4QXFE@35237|dsDNA viruses no RNA stage,4QS1Z@28883|Caudovirales,4QN8F@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_479440_1 1237149.C900_02036 2.24e-11 68.9 COG0330@1|root,COG0330@2|Bacteria,4NHJA@976|Bacteroidetes 976|Bacteroidetes O SPFH domain / Band 7 family - - - - - - - - - - - - Band_7 k59_457529_2 1379714.S5TND6_9CIRC 4.06e-17 84.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_67155_1 768066.HELO_2115 5.1e-24 98.6 COG2197@1|root,COG2197@2|Bacteria,1NA3X@1224|Proteobacteria 1224|Proteobacteria KT HNH endonuclease - - - - - - - - - - - - HNH_3 k59_252103_1 765913.ThidrDRAFT_1187 5.44e-101 307.0 COG0582@1|root,COG0582@2|Bacteria,1MWBN@1224|Proteobacteria,1RPD0@1236|Gammaproteobacteria,1WZ49@135613|Chromatiales 135613|Chromatiales L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_integrase k59_437734_1 1100720.ALKN01000018_gene1738 2.68e-46 168.0 COG1061@1|root,COG1061@2|Bacteria,1MV9F@1224|Proteobacteria,2VQF3@28216|Betaproteobacteria,4ADUP@80864|Comamonadaceae 28216|Betaproteobacteria L Helicase conserved C-terminal domain - - - - - - - - - - - - Helicase_C,ResIII,UPF0547 k59_519854_2 1458669.W6ASC9_9CAUD 6.23e-50 196.0 4QBSJ@10239|Viruses,4QXH4@35237|dsDNA viruses no RNA stage,4QPFJ@28883|Caudovirales,4QKUK@10699|Siphoviridae 10699|Siphoviridae S DNA primase activity - - - - - - - - - - - - - k59_438088_1 1423758.BN55_01455 3.54e-29 118.0 COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,1TPHP@1239|Firmicutes,4HC9M@91061|Bacilli,3F5AA@33958|Lactobacillaceae 91061|Bacilli KL DNA methylase - - - - - - - - - - - - N6_N4_Mtase,ParBc k59_107156_2 1288079.AUKN01000040_gene1507 1.01e-12 70.5 COG3291@1|root,COG3291@2|Bacteria,2IHHS@201174|Actinobacteria 201174|Actinobacteria S Pkd domain containing protein - - - - - - - - - - - - - k59_457866_1 1234888.K0A2J2_9VIRU 2.05e-59 201.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_524649_1 2045.KR76_13505 2.12e-46 165.0 COG0766@1|root,COG0766@2|Bacteria,2GJPW@201174|Actinobacteria,4DP2I@85009|Propionibacteriales 201174|Actinobacteria M EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) murA - 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - - EPSP_synthase,HTH_3 k59_524650_3 266264.Rmet_6534 5.43e-10 57.4 2EDZS@1|root,337UK@2|Bacteria,1NATD@1224|Proteobacteria,2VW7Y@28216|Betaproteobacteria,1KARX@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_501126_1 1086011.HJ01_01869 2.19e-16 79.3 COG0668@1|root,COG0668@2|Bacteria,4NH7C@976|Bacteroidetes,1ICX5@117743|Flavobacteriia,2NVTM@237|Flavobacterium 976|Bacteroidetes M Mechanosensitive ion channel - - - ko:K22044 - - - - ko00000,ko02000 1.A.23.3 - - MS_channel k59_152361_2 1147043.H9A108_9CAUD 2.35e-17 78.2 4QAKE@10239|Viruses,4QUP7@35237|dsDNA viruses no RNA stage,4QPCE@28883|Caudovirales,4QKTX@10699|Siphoviridae 10699|Siphoviridae S HNH endonuclease - - - - - - - - - - - - - k59_524659_2 1128912.GMES_2715 1.73e-10 67.4 COG2304@1|root,COG3204@1|root,COG3419@1|root,COG2304@2|Bacteria,COG3204@2|Bacteria,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,1RPV3@1236|Gammaproteobacteria,46578@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Tfp pilus assembly protein tip-associated adhesin pilY1 - - ko:K02674 - - - - ko00000,ko02035,ko02044 - - - Neisseria_PilC,VWA_2 k59_93509_1 445970.ALIPUT_00537 2.59e-48 172.0 COG0305@1|root,COG0305@2|Bacteria,4NF8P@976|Bacteroidetes,2FNG7@200643|Bacteroidia,22UPI@171550|Rikenellaceae 976|Bacteroidetes L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_194244_1 1524880.A0A076G697_9VIRU 0.00016 51.2 4QD1M@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_296885_1 1340534.S4WXX3_9CAUD 1.08e-14 75.1 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales 28883|Caudovirales S HNH endonuclease - - - - - - - - - - - - - k59_109414_1 278957.ABEA03000180_gene2028 2.93e-49 177.0 COG2804@1|root,COG2804@2|Bacteria,46SDR@74201|Verrucomicrobia,3K77E@414999|Opitutae 414999|Opitutae NU General secretory system II protein E domain protein - - - ko:K02454,ko:K02652 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 - - T2SSE,T2SSE_N k59_484650_1 105154.Q9MBU6_9VIRU 4.61e-94 291.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_442440_2 1458858.A0A088C4S7_9CAUD 8.03e-44 157.0 4QGM3@10239|Viruses,4QYG4@35237|dsDNA viruses no RNA stage,4QPTC@28883|Caudovirales,4QKCW@10662|Myoviridae 10662|Myoviridae S oxidoreductase activity - - - - - - - - - - - - - k59_461336_1 1220714.L7TNN0_9CAUD 1.75e-65 224.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QI9F@10662|Myoviridae 10662|Myoviridae S Type III restriction enzyme, res subunit - - - - - - - - - - - - - k59_461336_4 1094556.MCY_01183 8.3e-06 48.1 COG1044@1|root,COG1044@2|Bacteria,1NBEI@1224|Proteobacteria,2TZFU@28211|Alphaproteobacteria,48URD@772|Bartonellaceae 28211|Alphaproteobacteria M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell - - - - - - - - - - - - - k59_10223_2 1123267.JONN01000001_gene1032 0.000307 44.3 2B3XE@1|root,31WMD@2|Bacteria,1P4DI@1224|Proteobacteria,2UW3Y@28211|Alphaproteobacteria,2KBX1@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - Phage_CI_repr k59_525050_1 1618248.A0A0C5IB82_9CIRC 4.72e-12 70.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_234361_2 1101189.AQUO01000001_gene3030 6.61e-17 78.6 2E46I@1|root,32Z2G@2|Bacteria,1N9GR@1224|Proteobacteria,2UFE5@28211|Alphaproteobacteria,2PYX6@265|Paracoccus 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_137669_1 417280.A1YZY2_9CAUD 7.93e-30 122.0 4QCZC@10239|Viruses,4QX3V@35237|dsDNA viruses no RNA stage,4QRH3@28883|Caudovirales,4QHVR@10662|Myoviridae 10662|Myoviridae S Bacterial DNA polymerase III alpha subunit - - - - - - - - - - - - - k59_74898_2 205914.HS_1384 1.01e-111 355.0 28P6A@1|root,2ZC10@2|Bacteria,1RBZE@1224|Proteobacteria,1RRNS@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_198631_1 864702.OsccyDRAFT_0751 6.03e-30 118.0 2DCM2@1|root,32TZV@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_198631_4 667121.ET1_08_00770 1.76e-13 68.9 COG3613@1|root,COG3613@2|Bacteria,1NB40@1224|Proteobacteria,1SCJ5@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Domain of unknown function (DUF4406) - - - - - - - - - - - - DUF4406 k59_448436_1 408672.NBCG_03451 2.71e-66 214.0 COG1091@1|root,COG1898@1|root,COG1091@2|Bacteria,COG1898@2|Bacteria,2GNY8@201174|Actinobacteria,4DN84@85009|Propionibacteriales 201174|Actinobacteria M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose rfbD - 1.1.1.133,5.1.3.13 ko:K00067,ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777,R06514 RC00182,RC01531 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind,dTDP_sugar_isom k59_448436_2 1536773.R70331_28750 4.13e-08 54.7 COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,4HA3Y@91061|Bacilli,26RIV@186822|Paenibacillaceae 91061|Bacilli M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily spsJ - 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd k59_113069_1 509190.Cseg_0268 7.03e-14 79.7 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2TQMR@28211|Alphaproteobacteria,2KFHI@204458|Caulobacterales 204458|Caulobacterales V ABC transporter - - - ko:K06147,ko:K18893 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k59_588179_1 1158612.I580_01897 6.61e-61 193.0 COG0742@1|root,COG0742@2|Bacteria,1UN8R@1239|Firmicutes 1239|Firmicutes L ribosomal rna small subunit methyltransferase - - - - - - - - - - - - - k59_320722_1 521011.Mpal_0838 6.14e-09 64.3 COG0367@1|root,COG0449@1|root,arCOG00057@2157|Archaea,arCOG00071@2157|Archaea,2XV5E@28890|Euryarchaeota,2N9BC@224756|Methanomicrobia 224756|Methanomicrobia E TIGRFAM asparagine synthase (glutamine-hydrolyzing) asnB-1 - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 k59_279985_1 293826.Amet_0834 5.88e-70 229.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,36E1F@31979|Clostridiaceae 186801|Clostridia O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 k59_52341_3 456320.Mvol_1434 2.87e-12 62.4 COG3269@1|root,arCOG01641@2157|Archaea,2Y1N9@28890|Euryarchaeota,23R8T@183939|Methanococci 183939|Methanococci S PFAM Deoxyribonuclease rho motif-related TRAM - - - - - - - - - - - - TRAM k59_388532_1 1007869.M9MUW6_9CAUD 8.1e-09 62.4 4QDKP@10239|Viruses,4QZHT@35237|dsDNA viruses no RNA stage,4QTRD@28883|Caudovirales,4QJJC@10662|Myoviridae 10662|Myoviridae S transaminase activity - - - - - - - - - - - - - k59_19426_1 232721.Ajs_0943 7.63e-19 79.7 2BZU4@1|root,33P2G@2|Bacteria,1NMV2@1224|Proteobacteria,2VYVW@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_243126_3 1184251.TCELL_0579 3.04e-08 63.2 COG0582@1|root,arCOG01242@2157|Archaea,2XSQE@28889|Crenarchaeota 28889|Crenarchaeota L Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules xerA - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_4,Phage_integrase,zinc_ribbon_2 k59_510445_2 1298593.TOL_3056 1.09e-08 59.7 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria,1XJHS@135619|Oceanospirillales 135619|Oceanospirillales L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism - - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_203473_4 1121434.AULY01000011_gene1834 2.04e-26 107.0 2DZ82@1|root,32V6V@2|Bacteria,1N3UK@1224|Proteobacteria,431CX@68525|delta/epsilon subdivisions,2WX13@28221|Deltaproteobacteria,2M9YP@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - Tube k59_243132_2 1300345.LF41_1722 6.16e-48 163.0 COG0582@1|root,COG0582@2|Bacteria,1NWGS@1224|Proteobacteria,1S4PB@1236|Gammaproteobacteria,1X89K@135614|Xanthomonadales 135614|Xanthomonadales L Phage integrase family - - - - - - - - - - - - Phage_integrase k59_143427_2 266265.Bxe_A3055 6.8e-21 93.6 29F88@1|root,3025X@2|Bacteria,1NBJS@1224|Proteobacteria,2VWHK@28216|Betaproteobacteria,1KB80@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_326193_4 391587.KAOT1_16558 8.86e-52 168.0 COG0791@1|root,COG0791@2|Bacteria,4NPFE@976|Bacteroidetes,1I29F@117743|Flavobacteriia 976|Bacteroidetes M CHAP domain - - - - - - - - - - - - CHAP k59_429764_1 1464048.JNZS01000009_gene5875 6.27e-07 51.6 COG0791@1|root,COG0791@2|Bacteria,2GIWB@201174|Actinobacteria,4DC0B@85008|Micromonosporales 201174|Actinobacteria M NlpC/P60 family - - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - NLPC_P60 k59_634999_2 1004785.AMBLS11_09105 2.25e-05 51.6 COG0739@1|root,COG0739@2|Bacteria,1MY2X@1224|Proteobacteria,1RMYN@1236|Gammaproteobacteria,466FY@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0739 Membrane proteins related to metalloendopeptidases - - - - - - - - - - - - Peptidase_M23 k59_117968_1 691965.D4P7I0_9CAUD 2.02e-44 156.0 4QDSZ@10239|Viruses,4QXJ8@35237|dsDNA viruses no RNA stage,4QPKE@28883|Caudovirales,4QM8R@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_143429_1 1173762.S4TP25_9CAUD 7.67e-31 122.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_635003_1 309798.COPRO5265_1446 4.7e-56 186.0 arCOG06575@1|root,2Z7V5@2|Bacteria,1UZHZ@1239|Firmicutes,247UQ@186801|Clostridia,42GUK@68295|Thermoanaerobacterales 186801|Clostridia L Recognizes the double-stranded unmethylated sequence GATC and cleaves before G-1 dpnB - 3.1.21.4 ko:K01155 - - - - ko00000,ko01000,ko02048 - - - DpnII k59_326210_1 1201293.AKXQ01000054_gene4148 1.98e-09 63.2 COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1S1WF@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_int_SAM_4,Phage_integrase k59_266524_1 439375.Oant_0230 5.16e-63 202.0 COG0270@1|root,COG0270@2|Bacteria,1R5MR@1224|Proteobacteria,2U53Z@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_612401_1 1379712.S5TMV9_9CIRC 7.24e-18 87.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_429793_1 1234888.K0A2J2_9VIRU 6.9e-88 277.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_592831_2 1165094.RINTHH_3920 2.81e-73 234.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_266545_1 32057.KB217474_gene7975 8.11e-44 168.0 COG5545@1|root,COG5545@2|Bacteria,1G4RT@1117|Cyanobacteria,1HNNZ@1161|Nostocales 1117|Cyanobacteria S Virulence-associated protein E - - - - - - - - - - - - RepB_primase,VirE k59_56880_1 1395516.PMO01_03075 9.24e-17 80.9 2DP75@1|root,330U8@2|Bacteria,1N8XA@1224|Proteobacteria,1SCZN@1236|Gammaproteobacteria 1236|Gammaproteobacteria S HNH endonuclease - - - - - - - - - - - - AP2,HNH_3 k59_635076_1 1268240.ATFI01000007_gene431 1.44e-59 192.0 COG0863@1|root,COG0863@2|Bacteria,4NQQ1@976|Bacteroidetes,2G1PS@200643|Bacteroidia,4ARBB@815|Bacteroidaceae 976|Bacteroidetes L DNA methylase - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_185038_1 1126411.I1TEL3_9CIRC 2.83e-21 99.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_451651_4 1250006.JHZZ01000001_gene2354 6.24e-17 76.3 COG0758@1|root,COG0758@2|Bacteria 2|Bacteria LU DNA mediated transformation smf - - ko:K04096 - - - - ko00000 - - - DNA_processg_A,DUF2493,MoCo_carrier k59_534_1 178901.AmDm5_1686 7.58e-66 221.0 COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,2TQSP@28211|Alphaproteobacteria,2JPXK@204441|Rhodospirillales 204441|Rhodospirillales L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB - - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB k59_287520_2 1449351.RISW2_21770 2.45e-10 71.2 COG1196@1|root,COG3941@1|root,COG1196@2|Bacteria,COG3941@2|Bacteria 2|Bacteria O tape measure - - - - - - - - - - - - PhageMin_Tail,TMP_2,Tape_meas_lam_C k59_533624_1 574087.Acear_1218 1.61e-15 73.9 arCOG06669@1|root,2ZC1E@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_267113_2 882.DVU_2154 1.36e-25 101.0 COG0791@1|root,COG0791@2|Bacteria,1N732@1224|Proteobacteria,42Y2T@68525|delta/epsilon subdivisions,2WSQU@28221|Deltaproteobacteria,2MFUQ@213115|Desulfovibrionales 28221|Deltaproteobacteria M NlpC/P60 family - - - - - - - - - - - - NLPC_P60 k59_267113_4 1340493.JNIF01000003_gene3557 3.88e-10 68.9 COG3386@1|root,COG4625@1|root,COG3386@2|Bacteria,COG4625@2|Bacteria 2|Bacteria T pathogenesis - - 1.15.1.1,3.4.21.50 ko:K01337,ko:K04565,ko:K20276,ko:K21449 ko02024,ko04146,ko04213,ko05014,ko05016,ko05020,map02024,map04146,map04213,map05014,map05016,map05020 - - - ko00000,ko00001,ko01000,ko01002,ko02000 1.B.40.2 - - Autotransporter,He_PIG,SGL k59_328670_1 1002339.HMPREF9373_1750 0.000212 43.1 COG1694@1|root,COG1694@2|Bacteria,1N3XF@1224|Proteobacteria,1SSUP@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Mazg nucleotide pyrophosphohydrolase - - - - - - - - - - - - - k59_533629_1 1385658.U5KPZ6_9VIRU 6.29e-127 377.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_123427_1 1122176.KB903578_gene4850 9.04e-13 80.5 COG0726@1|root,COG3209@1|root,COG3291@1|root,COG3391@1|root,COG0726@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria 2|Bacteria CO amine dehydrogenase activity xlnB GO:0005575,GO:0016020 1.14.17.3,3.2.1.156,3.2.1.8 ko:K00504,ko:K01181,ko:K15531 - - - - ko00000,ko01000 - GH8 - CHU_C,Glyco_hydro_11,PKD,Polysacc_deac_1,SprB k59_61860_1 1234888.K0A2J2_9VIRU 3.27e-24 100.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_547_2 1227272.HMPREF1556_01379 4.89e-09 64.7 COG3774@1|root,COG3774@2|Bacteria 2|Bacteria M pathogenesis - - - - - - - - - - - - Anp1,Gly_transf_sug,Glycos_transf_2 k59_287526_4 105154.Q9MBU6_9VIRU 5.61e-88 275.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_996_1 1316936.K678_15209 1.31e-65 224.0 COG0305@1|root,COG0305@2|Bacteria,1QT50@1224|Proteobacteria,2TTND@28211|Alphaproteobacteria,2JV0Y@204441|Rhodospirillales 204441|Rhodospirillales L AAA domain - - - - - - - - - - - - Toprim_4 k59_287898_2 1165094.RINTHH_3920 4.71e-09 63.9 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_392816_1 1538804.A0A0A1CM43_9CAUD 9.54e-118 358.0 4QB5I@10239|Viruses,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_392821_2 1510531.JQJJ01000009_gene989 3.13e-09 62.4 COG5281@1|root,COG5281@2|Bacteria,1R47M@1224|Proteobacteria,2TUIV@28211|Alphaproteobacteria,3JY6I@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S COG5281, Phage-related minor tail protein - - - - - - - - - - - - - k59_597771_1 1692244.A0A0K1RLR5_9CIRC 2.76e-17 81.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_372145_2 398720.MED217_15260 1.19e-09 70.1 COG5295@1|root,COG5295@2|Bacteria,4NJTK@976|Bacteroidetes,1HZNB@117743|Flavobacteriia 976|Bacteroidetes UW surface antigen - - - - - - - - - - - - Peptidase_S74 k59_3542_1 926561.KB900620_gene3002 1.12e-07 59.7 COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,3WA77@53433|Halanaerobiales 186801|Clostridia L DNA polymerase III alpha subunit dnaE - 2.7.7.7 ko:K02337,ko:K14162 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k59_3542_2 111781.Lepto7376_1410 1.72e-12 73.9 COG2340@1|root,COG2340@2|Bacteria,1G4UZ@1117|Cyanobacteria,1HAAV@1150|Oscillatoriales 1117|Cyanobacteria Q Scp-like extracellular - - - - - - - - - - - - CAP,HemolysinCabind,PPC k59_639653_3 1385658.U5KPZ6_9VIRU 8.45e-216 615.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_516529_2 172088.AUGA01000071_gene7569 3.55e-61 207.0 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,2U6BJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S TIGRFAM phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_167293_1 375286.mma_2211 9.38e-46 157.0 COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,2W3M1@28216|Betaproteobacteria,475QA@75682|Oxalobacteraceae 28216|Betaproteobacteria L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_577773_1 1168289.AJKI01000019_gene2047 3.25e-07 57.4 COG0587@1|root,COG0587@2|Bacteria,4NE2R@976|Bacteroidetes,2FW95@200643|Bacteroidia,3XIXS@558415|Marinilabiliaceae 976|Bacteroidetes L DNA polymerase alpha chain like domain - - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP k59_413670_1 1692256.A0A0K1RL85_9CIRC 3.51e-66 215.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_557118_1 1122933.JNIY01000003_gene1007 7.7e-52 183.0 COG0004@1|root,COG0004@2|Bacteria,2GIZK@201174|Actinobacteria,4F1S2@85016|Cellulomonadaceae 201174|Actinobacteria P Ammonium Transporter Family amt - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp k59_105289_1 742733.HMPREF9469_05039 2.04e-45 169.0 28JED@1|root,2Z98K@2|Bacteria,1TW1U@1239|Firmicutes,24CFD@186801|Clostridia,2226E@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - GerE k59_599269_1 1121423.JONT01000003_gene1096 0.000106 49.3 COG3409@1|root,COG3773@1|root,COG3409@2|Bacteria,COG3773@2|Bacteria,1TRFW@1239|Firmicutes,24912@186801|Clostridia,261NC@186807|Peptococcaceae 186801|Clostridia M Cell wall hydrolase sleB - 3.5.1.28 ko:K01449 - - R04112 RC00064,RC00141 ko00000,ko01000 - - - Hydrolase_2,PG_binding_1 k59_641914_1 145579.CAPSD_BPPHM 8.81e-52 190.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_373685_2 335797.C7BGG1_9CAUD 2.36e-07 58.2 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales,4QKWY@10699|Siphoviridae 10699|Siphoviridae S DNA helicase activity - - - - - - - - - - - - - k59_518534_3 1038860.AXAP01000015_gene2006 5.53e-90 288.0 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,2U6BJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S TIGRFAM phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_168839_1 247490.KSU1_D0180 5.98e-24 105.0 COG0209@1|root,COG0209@2|Bacteria 2|Bacteria F ribonucleoside-diphosphate reductase activity rtpR - 1.1.98.6,1.17.4.1 ko:K00525,ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024,R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,LAGLIDADG_3,Ribonuc_red_lgC k59_168839_3 536233.CLO_1816 3.8e-28 108.0 COG0863@1|root,COG0863@2|Bacteria,1V0ZF@1239|Firmicutes,24CQV@186801|Clostridia,36J76@31979|Clostridiaceae 186801|Clostridia L Belongs to the N(4) N(6)-methyltransferase family - - - - - - - - - - - - N6_N4_Mtase k59_352596_1 1297570.MESS4_510150 8.72e-11 64.7 2DP75@1|root,330U8@2|Bacteria,1N8XA@1224|Proteobacteria,2UIHW@28211|Alphaproteobacteria,43QHP@69277|Phyllobacteriaceae 28211|Alphaproteobacteria L Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - - - - - - - - - - AP2,HNH_3 k59_558200_1 1095743.HMPREF1054_2026 0.000367 50.4 COG5185@1|root,COG5281@1|root,COG5185@2|Bacteria,COG5281@2|Bacteria 2|Bacteria D sister chromatid segregation - - 3.2.1.18 ko:K01186,ko:K21471,ko:K22051 ko00511,ko00600,ko04142,map00511,map00600,map04142 - R04018 RC00028,RC00077 ko00000,ko00001,ko01000,ko01002,ko01011,ko02000,ko02042 1.A.23.1.2,1.A.23.1.3 GH33 - Phage_HK97_TLTM k59_5231_2 161934.XP_010680182.1 2.05e-49 174.0 COG2256@1|root,KOG2028@2759|Eukaryota,37PNU@33090|Viridiplantae,3G93Y@35493|Streptophyta 35493|Streptophyta L AAA-type ATPase family protein - GO:0000731,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006139,GO:0006259,GO:0006275,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010556,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030174,GO:0031323,GO:0031326,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0071897,GO:0080090,GO:0090304,GO:0090329,GO:1901360,GO:1901362,GO:1901576,GO:2000112 - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,UBA k59_578878_3 342113.DM82_4547 5.49e-14 75.5 COG1387@1|root,COG1387@2|Bacteria,1MYXV@1224|Proteobacteria,2VJIQ@28216|Betaproteobacteria,1K4RW@119060|Burkholderiaceae 28216|Betaproteobacteria L DNA polymerase - - - ko:K02347 - - - - ko00000,ko03400 - - - DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP k59_334747_1 1542743.A0A088G061_9VIRU 2.54e-33 132.0 4QHM9@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_128593_1 445972.ANACOL_00151 4.93e-07 51.2 COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,24HF9@186801|Clostridia,3WJAP@541000|Ruminococcaceae 186801|Clostridia L Single-stranded DNA-binding protein ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_539924_1 1123325.JHUV01000001_gene109 9.65e-24 100.0 2DMHT@1|root,32RN3@2|Bacteria 2|Bacteria - - MA20_36130 - - - - - - - - - - - PEGA k59_189918_3 1219072.VHA01S_087_00080 8.78e-47 174.0 COG0714@1|root,COG0714@2|Bacteria,1PC08@1224|Proteobacteria,1RQ5U@1236|Gammaproteobacteria,1Y0U5@135623|Vibrionales 135623|Vibrionales S AAA domain (dynein-related subfamily) - - - - - - - - - - - - AAA_5 k59_540491_1 272942.RCAP_rcc02341 2.69e-12 72.8 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2TSDW@28211|Alphaproteobacteria,1FCC1@1060|Rhodobacter 28211|Alphaproteobacteria S Phage Terminase terL2 - - - - - - - - - - - Terminase_1 k59_67410_1 397290.C810_01484 1.35e-34 130.0 2CWXD@1|root,32T0J@2|Bacteria,1VCVP@1239|Firmicutes,24MPK@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_353620_1 485918.Cpin_3879 1.49e-57 198.0 COG1783@1|root,COG1783@2|Bacteria,4PN7V@976|Bacteroidetes 976|Bacteroidetes S Terminase-like family - - - - - - - - - - - - Terminase_3,Terminase_6 k59_252354_1 1127692.HMPREF9075_00069 2.23e-69 232.0 COG0553@1|root,COG0863@1|root,COG0553@2|Bacteria,COG0863@2|Bacteria,4NHHF@976|Bacteroidetes,1I7WE@117743|Flavobacteriia,1EQNF@1016|Capnocytophaga 976|Bacteroidetes KL DNA methylase - - - - - - - - - - - - Helicase_C,N6_N4_Mtase,SNF2_N k59_600489_1 1122212.AULO01000011_gene505 0.000104 51.6 COG3210@1|root,COG3210@2|Bacteria,1MXIP@1224|Proteobacteria,1RSAX@1236|Gammaproteobacteria,1XRXS@135619|Oceanospirillales 135619|Oceanospirillales U The GLUG motif - - - - - - - - - - - - Glug,Haemagg_act k59_621475_4 1327036.R4JHP8_9CAUD 1.6e-13 77.4 4QCEF@10239|Viruses,4QVWZ@35237|dsDNA viruses no RNA stage,4QTBA@28883|Caudovirales,4QMGR@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_437904_2 1009370.ALO_12376 1.03e-20 89.7 2EC8I@1|root,33670@2|Bacteria,1VENI@1239|Firmicutes,4H668@909932|Negativicutes 909932|Negativicutes - - - - - - - - - - - - - - - k59_559888_2 537874.B3GVX7_9CAUD 2.28e-28 112.0 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales,4QKM7@10699|Siphoviridae 10699|Siphoviridae S HNH endonuclease - - - - - - - - - - - - - k59_644311_1 205918.Psyr_2827 9.5e-35 132.0 COG0175@1|root,COG0175@2|Bacteria,1PZ96@1224|Proteobacteria,1SBUC@1236|Gammaproteobacteria 1236|Gammaproteobacteria EH Phosphoadenosine phosphosulfate reductase family - - - - - - - - - - - - PAPS_reduct k59_149890_1 1500281.JQKZ01000020_gene3218 1.42e-30 123.0 29XK5@1|root,30JB8@2|Bacteria,4PN9G@976|Bacteroidetes,1IK1X@117743|Flavobacteriia,3ZSWM@59732|Chryseobacterium 976|Bacteroidetes - - - - - - - - - - - - - - - k59_340845_1 945712.CULC22_01185 2.49e-20 94.7 COG0553@1|root,COG0553@2|Bacteria,2IC31@201174|Actinobacteria,22MAR@1653|Corynebacteriaceae 201174|Actinobacteria KL Superfamily II DNA RNA helicases, SNF2 family - - - - - - - - - - - - SNF2_N k59_625863_3 1349820.M707_02560 1.1e-14 76.3 COG0270@1|root,COG0270@2|Bacteria,2I8R8@201174|Actinobacteria 201174|Actinobacteria H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_546032_1 1005048.CFU_2230 1.58e-10 69.7 COG3468@1|root,COG3468@2|Bacteria,1QUZ3@1224|Proteobacteria,2WGMH@28216|Betaproteobacteria,4731U@75682|Oxalobacteraceae 28216|Betaproteobacteria MU Autotransporter beta-domain - - - - - - - - - - - - Autotransporter,He_PIG k59_316558_3 1458462.JNLK01000001_gene350 8.28e-19 96.7 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,27J0X@186928|unclassified Lachnospiraceae 186801|Clostridia KL SNF2 family N-terminal domain - - - - - - - - - - - - SNF2_N k59_257429_3 203275.BFO_1851 2.67e-07 52.0 COG0729@1|root,COG0729@2|Bacteria,4NVBC@976|Bacteroidetes,2FTDT@200643|Bacteroidia,22YG7@171551|Porphyromonadaceae 976|Bacteroidetes M Chaperone of endosialidase - - - - - - - - - - - - Peptidase_S74 k59_195253_2 445971.ANASTE_00711 8.02e-18 91.3 COG1783@1|root,COG1783@2|Bacteria,1TRQP@1239|Firmicutes,248E9@186801|Clostridia,25YQA@186806|Eubacteriaceae 186801|Clostridia S Phage terminase, large subunit, PBSX family - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C k59_213456_1 1219065.VPR01S_01_02560 1.27e-06 55.8 2C3WM@1|root,3002C@2|Bacteria,1RDC0@1224|Proteobacteria,1TIHI@1236|Gammaproteobacteria,1XZ4X@135623|Vibrionales 135623|Vibrionales S Domain of unknown function (DUF4326) - - - - - - - - - - - - DUF4326 k59_49833_2 1618248.A0A0C5IB82_9CIRC 4.83e-77 244.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_462722_1 398525.KB900701_gene5079 1.35e-09 56.2 COG0791@1|root,COG0791@2|Bacteria,1N732@1224|Proteobacteria,2UH6X@28211|Alphaproteobacteria,3K18Y@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M NlpC/P60 family - - - - - - - - - - - - NLPC_P60 k59_30823_1 1120979.ATVB01000007_gene1117 6.46e-09 61.2 28MKK@1|root,2ZAWR@2|Bacteria,2IS2W@201174|Actinobacteria,4D1DD@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - RNA_helicase,Viral_Rep k59_110170_2 1397696.KK211189_gene1853 6.75e-05 48.9 COG1738@1|root,COG1738@2|Bacteria,1TSAY@1239|Firmicutes,4HB9T@91061|Bacilli,3WFVD@539002|Bacillales incertae sedis 91061|Bacilli S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage ypdP - - ko:K09125 - - - - ko00000 - - - Vut_1 k59_547119_1 1537917.JU82_03700 6.19e-32 122.0 COG0553@1|root,COG0553@2|Bacteria 2|Bacteria L helicase activity - - - - - - - - - - - - Helicase_C,PLDc_2,ResIII,SNF2_N k59_486270_1 526226.Gbro_1519 1.11e-11 70.9 COG3757@1|root,COG3757@2|Bacteria,2GKS0@201174|Actinobacteria,4GBJN@85026|Gordoniaceae 201174|Actinobacteria M Glycosyl hydrolases family 25 - - - ko:K07273 - - - - ko00000 - - - Glyco_hydro_25,PG_binding_1 k59_526844_2 266762.HQ36_05355 2.37e-41 141.0 COG3023@1|root,COG3023@2|Bacteria,4NQ2J@976|Bacteroidetes,2FS4K@200643|Bacteroidia,230M3@171551|Porphyromonadaceae 976|Bacteroidetes V Ami_2 - - 3.5.1.28 ko:K01447 - - R04112 RC00064,RC00141 ko00000,ko01000 - - - Amidase_2 k59_235549_4 1436889.W6ASR9_9CAUD 7.09e-09 63.5 4QFN8@10239|Viruses,4QYWE@35237|dsDNA viruses no RNA stage,4QS52@28883|Caudovirales,4QP1K@10744|Podoviridae 10744|Podoviridae S metal ion binding - - - - - - - - - - - - - k59_341865_1 2003327.CAPSD_BPCHP 2.18e-30 120.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_195270_2 1692252.A0A0K1RL35_9CIRC 1.53e-110 330.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_49858_1 1475143.W8SNN0_9CIRC 6.03e-35 131.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_361317_1 221915.Q6Y7T9_BPPGK 5.97e-21 93.6 4QBHW@10239|Viruses,4QVHG@35237|dsDNA viruses no RNA stage,4QTT7@28883|Caudovirales,4QJZQ@10662|Myoviridae 10662|Myoviridae S sequence-specific DNA binding transcription factor activity - - - - - - - - - - - - - k59_348266_2 1379715.S5TMW6_9CIRC 5.8e-18 83.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_348266_3 1692244.A0A0K1RLR5_9CIRC 2.84e-61 197.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_16924_1 1089547.KB913013_gene172 3.62e-15 79.3 COG3740@1|root,COG3740@2|Bacteria,4NW89@976|Bacteroidetes,47SZC@768503|Cytophagia 976|Bacteroidetes S Caudovirus prohead serine protease - - - ko:K06904 - - - - ko00000 - - - Peptidase_S78 k59_385748_2 1692249.A0A0K1RL40_9CIRC 9.22e-77 241.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_158429_1 160492.XF_2691 0.000204 47.0 COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,1RMFR@1236|Gammaproteobacteria,1X3U9@135614|Xanthomonadales 135614|Xanthomonadales K RNA polymerase sigma factor RpoH rpoH - - ko:K03089 - - - - ko00000,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r4 k59_36023_1 145579.REP_BPPHM 0.000246 50.4 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_77353_3 1500259.JQLD01000001_gene3655 1.71e-07 59.7 COG4653@1|root,COG4653@2|Bacteria,1R171@1224|Proteobacteria,2TYXN@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Phage capsid family - - - - - - - - - - - - Phage_capsid k59_632035_1 880073.Calab_1470 1.8e-20 86.7 COG0270@1|root,COG0270@2|Bacteria 2|Bacteria L DNA (cytosine-5-)-methyltransferase activity dcm - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_468694_1 28042.GU90_04365 1.76e-15 73.6 2F2UR@1|root,33VQR@2|Bacteria,2IN2B@201174|Actinobacteria,4E553@85010|Pseudonocardiales 201174|Actinobacteria S Domain of unknown function (DUF4326) - - - - - - - - - - - - DUF4326 k59_217718_1 1476391.X5KNB4_9CAUD 1.2e-43 185.0 4QAXA@10239|Viruses,4QYJI@35237|dsDNA viruses no RNA stage,4QQ1A@28883|Caudovirales,4QNU7@10744|Podoviridae 10744|Podoviridae S metallopeptidase activity - - - - - - - - - - - - - k59_636634_1 1134413.ANNK01000054_gene2225 3.77e-12 64.3 2E38J@1|root,32Y88@2|Bacteria,1VAXK@1239|Firmicutes,4HNXW@91061|Bacilli,1ZHZI@1386|Bacillus 91061|Bacilli S VRR_NUC - - - - - - - - - - - - VRR_NUC k59_636634_2 1157490.EL26_01805 1.64e-08 57.8 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4H9YP@91061|Bacilli,2791R@186823|Alicyclobacillaceae 91061|Bacilli KL SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,SNF2_N k59_472713_1 574376.BAMA_02055 2.32e-30 137.0 COG4983@1|root,COG5519@1|root,COG4983@2|Bacteria,COG5519@2|Bacteria,1TSFH@1239|Firmicutes,4HFH5@91061|Bacilli,1ZD36@1386|Bacillus 91061|Bacilli L Domain of unknown function (DUF927) - - - - - - - - - - - - DUF927 k59_103123_3 945712.CULC22_01190 1.12e-17 93.6 COG2887@1|root,COG2887@2|Bacteria,2IBBB@201174|Actinobacteria,22K0W@1653|Corynebacteriaceae 201174|Actinobacteria L Protein of unknown function (DUF2800) - - - - - - - - - - - - DUF2800 k59_472726_1 1123288.SOV_1c10590 4.32e-29 119.0 COG3378@1|root,COG3378@2|Bacteria,1TQP9@1239|Firmicutes,4H4C8@909932|Negativicutes 909932|Negativicutes S D5 N terminal like - - - - - - - - - - - - D5_N,Pox_D5 k59_267572_1 994573.T472_0210840 3.95e-42 153.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,36DK9@31979|Clostridiaceae 186801|Clostridia L snf2 family - - - - - - - - - - - - SNF2_N k59_410959_1 644968.DFW101_3487 3.66e-07 58.2 2AG31@1|root,3167H@2|Bacteria,1NGCE@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_493004_1 1692256.A0A0K1RL85_9CIRC 1.7e-84 263.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_390464_1 1173762.S4TP28_9CAUD 9.27e-61 207.0 4QGA5@10239|Viruses,4QURD@35237|dsDNA viruses no RNA stage,4QT9N@28883|Caudovirales,4QP47@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_288153_2 1217718.ALOU01000019_gene2655 0.000128 45.4 COG0568@1|root,COG0568@2|Bacteria,1MUDI@1224|Proteobacteria,2VIUT@28216|Betaproteobacteria,1K412@119060|Burkholderiaceae 28216|Betaproteobacteria K RNA polymerase sigma factor RpoS rpoS - - ko:K03087 ko02026,ko05111,map02026,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 k59_41899_1 654929.REP_PCV1C 8.05e-32 125.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_41899_3 1676988.A0A0H4FV52_9CIRC 3.02e-46 167.0 4QGVY@10239|Viruses,4QUKN@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_41899_4 1618236.A0A0C5IB23_9CIRC 2.21e-21 92.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_247524_1 197221.22294879 5.17e-41 145.0 COG1351@1|root,COG1351@2|Bacteria,1GDYD@1117|Cyanobacteria 1117|Cyanobacteria F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - - - - - - - - - - Thy1 k59_62524_1 1120951.AUBG01000002_gene1173 4.7e-30 122.0 COG0467@1|root,COG0467@2|Bacteria,4NIAQ@976|Bacteroidetes,1I265@117743|Flavobacteriia 976|Bacteroidetes T AAA domain - - - - - - - - - - - - AAA_25 k59_164985_6 196490.AUEZ01000158_gene5994 6.48e-13 64.7 2EMWV@1|root,33FJ4@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_83315_1 2003327.CAPSD_BPCHP 5.49e-19 92.8 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_247532_1 369723.Strop_2108 6.34e-14 77.8 COG0367@1|root,COG0367@2|Bacteria,2I9UP@201174|Actinobacteria,4D9YF@85008|Micromonosporales 201174|Actinobacteria E Glutamine amidotransferase domain - - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 k59_452389_1 655097.C8ZKG2_9CAUD 3.41e-24 103.0 4QGA5@10239|Viruses,4QURD@35237|dsDNA viruses no RNA stage,4QT9N@28883|Caudovirales,4QP47@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_477624_2 742740.HMPREF9474_02302 2.17e-16 74.7 2E0G5@1|root,324TP@2|Bacteria,1UQZN@1239|Firmicutes,258ST@186801|Clostridia,222Q1@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_189041_1 649831.L083_6423 0.000488 48.5 COG1572@1|root,COG1572@2|Bacteria,2H1Z9@201174|Actinobacteria,4D9C8@85008|Micromonosporales 201174|Actinobacteria S CARDB - - - - - - - - - - - - Beta_helix,CARDB,F5_F8_type_C k59_518097_2 1449336.JQLO01000001_gene1124 9.26e-13 67.0 COG1694@1|root,COG1694@2|Bacteria,1VIQA@1239|Firmicutes,4HM6C@91061|Bacilli 91061|Bacilli S Nucleotide pyrophosphohydrolase - - - - - - - - - - - - MazG k59_518097_3 1408428.JNJP01000026_gene342 2.94e-32 125.0 28HR1@1|root,2Z7YI@2|Bacteria,1R47S@1224|Proteobacteria,42NUC@68525|delta/epsilon subdivisions,2WM38@28221|Deltaproteobacteria,2M896@213115|Desulfovibrionales 28221|Deltaproteobacteria S Putative amidoligase enzyme - - - - - - - - - - - - Amidoligase_2 k59_393806_1 83219.PM02_19300 2.56e-19 99.0 COG2911@1|root,COG2931@1|root,COG5276@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria,COG5276@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q COG2931 RTX toxins and related Ca2 -binding proteins - - - - - - - - - - - - Cadherin_3,DUF4214,GDPD,He_PIG,HemolysinCabind,PPC,Peptidase_M10_C k59_65802_2 1382305.AZUC01000063_gene3210 4.16e-05 54.3 COG0616@1|root,COG0616@2|Bacteria,1TRQW@1239|Firmicutes,4HB4R@91061|Bacilli,26DSC@186818|Planococcaceae 91061|Bacilli OU Peptidase family S49 sppA - - ko:K04773 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49 k59_251079_2 1217656.F964_00545 0.000213 48.5 COG3740@1|root,COG3740@2|Bacteria,1QJGG@1224|Proteobacteria,1SQG3@1236|Gammaproteobacteria,3NMP5@468|Moraxellaceae 1236|Gammaproteobacteria S Caudovirus prohead serine protease - - - - - - - - - - - - Peptidase_S78 k59_148042_3 1385658.U5KPZ6_9VIRU 1.97e-11 65.5 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_333405_4 1223545.GS4_39_00550 9.82e-10 66.2 COG3953@1|root,COG5283@1|root,COG5412@1|root,COG3953@2|Bacteria,COG5283@2|Bacteria,COG5412@2|Bacteria,2I92I@201174|Actinobacteria,4GCJR@85026|Gordoniaceae 201174|Actinobacteria M Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_456309_2 428125.CLOLEP_01415 1.89e-77 237.0 28NM4@1|root,2ZBMQ@2|Bacteria,1V1QD@1239|Firmicutes,24G1B@186801|Clostridia,3WNFY@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_333411_1 1121346.KB899820_gene2840 1.31e-17 89.0 COG5301@1|root,COG5301@2|Bacteria,1VEZ9@1239|Firmicutes,4HNUH@91061|Bacilli,26TPX@186822|Paenibacillaceae 91061|Bacilli G cellulose 1,4-beta-cellobiosidase activity - - - - - - - - - - - - - k59_168482_2 1429916.X566_20585 1.97e-62 197.0 COG1738@1|root,COG1738@2|Bacteria,1RDSF@1224|Proteobacteria,2U7ZF@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage - - - ko:K09125 - - - - ko00000 - - - Vut_1 k59_168482_3 1318628.MARLIPOL_10926 6.46e-23 98.2 COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,1RMG9@1236|Gammaproteobacteria,465AV@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) queC - 6.3.4.20 ko:K06920 ko00790,ko01100,map00790,map01100 - R09978 RC00959 ko00000,ko00001,ko01000,ko03016 - - - QueC k59_456318_1 114615.BRADO2879 6.26e-09 58.5 COG2520@1|root,COG2520@2|Bacteria,1RIYU@1224|Proteobacteria,2U2ZF@28211|Alphaproteobacteria,3JSC4@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Methyltransferase FkbM domain - - - - - - - - - - - - Methyltransf_21 k59_394362_1 1385658.U5KPZ6_9VIRU 4.74e-98 308.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_128301_1 1218076.BAYB01000051_gene6029 8.57e-16 86.7 COG4653@1|root,COG4653@2|Bacteria,1Q3BS@1224|Proteobacteria,2VT2K@28216|Betaproteobacteria,1K7FS@119060|Burkholderiaceae 28216|Betaproteobacteria S Phage major capsid protein - - - - - - - - - - - - Phage_capsid k59_599602_1 1234888.K0A2J2_9VIRU 6.15e-107 329.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_251700_1 318464.IO99_00635 6.95e-09 66.6 COG5281@1|root,COG5281@2|Bacteria,1TPWF@1239|Firmicutes,24A8R@186801|Clostridia,36GW3@31979|Clostridiaceae 186801|Clostridia S tape measure - - - - - - - - - - - - - k59_25252_1 1385658.U5KPZ6_9VIRU 1.33e-66 219.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_543267_2 981383.AEWH01000051_gene471 5.76e-09 60.1 COG4734@1|root,COG4734@2|Bacteria,1TNY7@1239|Firmicutes,4HDCV@91061|Bacilli 91061|Bacilli S Antirestriction protein (ArdA) - - - - - - - - - - - - ArdA k59_131675_1 305700.B447_10643 7.03e-23 95.5 COG2197@1|root,COG2197@2|Bacteria,1NA3X@1224|Proteobacteria,2VW90@28216|Betaproteobacteria 28216|Betaproteobacteria KT HNH endonuclease - - - - - - - - - - - - HNH_3 k59_172977_1 69328.PVLB_20830 1.04e-13 75.9 COG4695@1|root,COG4695@2|Bacteria,1MUP5@1224|Proteobacteria,1RPB0@1236|Gammaproteobacteria 1236|Gammaproteobacteria S portal protein - - - - - - - - - - - - Phage_portal k59_151332_1 1437882.AZRU01000006_gene1499 1.85e-11 63.9 COG0582@1|root,COG0582@2|Bacteria,1NWGS@1224|Proteobacteria,1S1RT@1236|Gammaproteobacteria,1YG3N@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria L Phage integrase family - - - - - - - - - - - - Phage_integrase k59_28274_1 1121396.KB892966_gene957 6.85e-30 127.0 COG0305@1|root,COG3598@1|root,COG0305@2|Bacteria,COG3598@2|Bacteria,1R4EA@1224|Proteobacteria,42TKF@68525|delta/epsilon subdivisions,2WQ0D@28221|Deltaproteobacteria,2MNNZ@213118|Desulfobacterales 28221|Deltaproteobacteria L AAA domain - - - - - - - - - - - - AAA_25 k59_92570_1 1026955.F5B3N6_9CAUD 0.00027 47.4 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QI82@10662|Myoviridae 10662|Myoviridae S virus tail, fiber - - - - - - - - - - - - - k59_441410_1 105154.Q9MBU6_9VIRU 7.48e-129 392.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_441410_2 105154.Q9MBU3_9VIRU 1.15e-11 67.4 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_524087_2 691965.D4P7E6_9CAUD 4.01e-55 195.0 4QAK6@10239|Viruses,4R01K@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_108948_2 382640.BT_2229 1.19e-14 72.0 COG3772@1|root,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,2U7X4@28211|Alphaproteobacteria,48TF4@772|Bartonellaceae 28211|Alphaproteobacteria G Phage lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_92596_2 318464.IO99_00635 3.77e-09 66.2 COG5281@1|root,COG5281@2|Bacteria,1TPWF@1239|Firmicutes,24A8R@186801|Clostridia,36GW3@31979|Clostridiaceae 186801|Clostridia S tape measure - - - - - - - - - - - - - k59_624621_1 710685.MycrhN_2819 2.3e-42 158.0 COG0392@1|root,COG0671@1|root,COG3642@1|root,COG0392@2|Bacteria,COG0671@2|Bacteria,COG3642@2|Bacteria,2GMAV@201174|Actinobacteria,234XJ@1762|Mycobacteriaceae 201174|Actinobacteria T integral membrane protein - - 3.6.1.27 ko:K07027,ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011,ko02000 4.D.2 - - LPG_synthase_TM,PAP2 k59_355936_1 1609634.A0A0C5ANA6_9VIRU 7.54e-08 59.3 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_377883_1 444875.E3SMD8_9CAUD 1.3e-86 260.0 4QD0J@10239|Viruses,4R0A5@35237|dsDNA viruses no RNA stage,4QSK9@28883|Caudovirales,4QNR4@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_566150_1 145579.CAPSD_BPPHM 1.25e-31 127.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_319499_1 1163409.UUA_11403 8.3e-22 97.1 COG0438@1|root,COG0438@2|Bacteria,1N01H@1224|Proteobacteria,1S8Z9@1236|Gammaproteobacteria,1X5Z9@135614|Xanthomonadales 135614|Xanthomonadales M glycosyltransferase - - - - - - - - - - - - Glyco_trans_1_4,Glycos_transf_1 k59_300213_1 755731.Clo1100_2438 4.67e-37 141.0 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1TSMG@1239|Firmicutes,248S7@186801|Clostridia,36FFT@31979|Clostridiaceae 186801|Clostridia S TIGRFAM Phage - - - - - - - - - - - - Terminase_6,Terminase_6C k59_446962_1 411901.BACCAC_01168 1.19e-47 160.0 29XC7@1|root,30J1Z@2|Bacteria,4PMTX@976|Bacteroidetes,2FR7E@200643|Bacteroidia,4APEM@815|Bacteroidaceae 976|Bacteroidetes S Domain of unknown function (DUF3560) - - - - - - - - - - - - DUF3560 k59_215386_2 926567.TheveDRAFT_0494 0.000235 43.5 COG0720@1|root,COG0720@2|Bacteria,3TB85@508458|Synergistetes 508458|Synergistetes H PFAM 6-pyruvoyl tetrahydropterin synthase - - 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 - - - PTPS k59_654054_2 145579.REP_BPPHM 1.96e-18 89.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_489474_2 216591.pBCA072 8.36e-10 64.7 COG0863@1|root,COG0863@2|Bacteria,1R7KV@1224|Proteobacteria,2VU55@28216|Betaproteobacteria,1KB3M@119060|Burkholderiaceae 28216|Betaproteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.72 ko:K00571,ko:K07319 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_98770_1 1316936.K678_00030 2.01e-29 121.0 COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,2TS8W@28211|Alphaproteobacteria,2JR1Y@204441|Rhodospirillales 204441|Rhodospirillales D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N k59_111973_1 342113.DM82_3252 3.53e-52 186.0 COG2189@1|root,COG2189@2|Bacteria,1MX9M@1224|Proteobacteria,2VGZB@28216|Betaproteobacteria 28216|Betaproteobacteria L PFAM DNA methylase N-4 N-6 - - 2.1.1.72 ko:K07316 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_155828_1 1380387.JADM01000008_gene932 1.44e-07 57.8 COG5492@1|root,COG5492@2|Bacteria,1R065@1224|Proteobacteria 1224|Proteobacteria N domain, Protein - - - - - - - - - - - - - k59_98803_3 1173762.S4TRN6_9CAUD 4.29e-18 84.7 4QBMV@10239|Viruses,4QUU6@35237|dsDNA viruses no RNA stage,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_566172_3 1540257.JQMW01000004_gene519 7.66e-09 59.7 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,24ANG@186801|Clostridia,36F6H@31979|Clostridiaceae 186801|Clostridia P E1-E2 ATPase-associated domain protein - - - - - - - - - - - - Cation_ATPase,Cation_ATPase_N,E1-E2_ATPase k59_466111_1 1692252.A0A0K1RL35_9CIRC 4.63e-23 99.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_51963_1 1357279.N018_05420 0.000411 44.3 2E1G4@1|root,32WUP@2|Bacteria,1N4N0@1224|Proteobacteria,1SQHB@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_51963_2 629773.AORY01000012_gene1039 8.67e-91 282.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2TSDW@28211|Alphaproteobacteria,2K42P@204457|Sphingomonadales 204457|Sphingomonadales S Terminase - - - - - - - - - - - - Terminase_1 k59_260539_3 717772.THIAE_06200 3.99e-32 121.0 COG1961@1|root,COG1961@2|Bacteria,1MXXT@1224|Proteobacteria,1S08N@1236|Gammaproteobacteria,4611V@72273|Thiotrichales 72273|Thiotrichales L Resolvase, N terminal domain - - - - - - - - - - - - HTH_7,Resolvase k59_364969_2 1217656.F964_00566 1.35e-30 116.0 COG3935@1|root,COG3935@2|Bacteria,1N2SH@1224|Proteobacteria,1SBMX@1236|Gammaproteobacteria,3NTFF@468|Moraxellaceae 1236|Gammaproteobacteria L DnaD domain protein - - - - - - - - - - - - - k59_326636_1 1385658.U5KPZ6_9VIRU 1.17e-112 345.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_612692_1 76114.ebA5486 2.4e-10 66.2 COG3740@1|root,COG3740@2|Bacteria,1QVIJ@1224|Proteobacteria,2WGSR@28216|Betaproteobacteria 28216|Betaproteobacteria S Phage capsid family - - - - - - - - - - - - Phage_capsid k59_306245_1 272942.RCAP_rcc02911 1.23e-10 70.1 COG1511@1|root,COG5281@1|root,COG1511@2|Bacteria,COG5281@2|Bacteria 2|Bacteria D sister chromatid segregation - - - - - - - - - - - - Peptidase_M23,PhageMin_Tail,Phage_HK97_TLTM,TMP_2,Tape_meas_lam_C k59_306245_5 999541.bgla_1g10940 3.16e-05 50.1 2EDKQ@1|root,337GJ@2|Bacteria,1NAT9@1224|Proteobacteria,2VXFY@28216|Betaproteobacteria,1KEM3@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_389543_2 945712.CULC22_01186 9.45e-09 55.5 2E38J@1|root,32Y88@2|Bacteria,2GX8Q@201174|Actinobacteria,22P5P@1653|Corynebacteriaceae 201174|Actinobacteria S VRR_NUC - - - - - - - - - - - - VRR_NUC k59_39702_1 196490.AUEZ01000004_gene4000 8.22e-14 79.3 COG4733@1|root,COG4733@2|Bacteria,1Q2WW@1224|Proteobacteria,2TUS9@28211|Alphaproteobacteria,3JZVG@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Phage-related protein, tail component - - - - - - - - - - - - DUF1983,Phage-tail_3 k59_80634_3 349521.HCH_02886 2.26e-14 70.1 COG3023@1|root,COG3023@2|Bacteria,1N032@1224|Proteobacteria,1SFIP@1236|Gammaproteobacteria,1XPM6@135619|Oceanospirillales 135619|Oceanospirillales V N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - Amidase_2 k59_635460_1 759938.F5BSB4_9CIRC 4.17e-10 64.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_286121_1 1134445.AJJM01000011_gene3537 7.59e-18 89.0 2CHG1@1|root,32YZS@2|Bacteria,2IRMN@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_244733_2 105154.Q9MBU3_9VIRU 1.67e-13 74.3 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_409945_1 568816.Acin_1836 4.45e-48 170.0 COG0507@1|root,COG5323@1|root,COG0507@2|Bacteria,COG5323@2|Bacteria,1TQWH@1239|Firmicutes,4H656@909932|Negativicutes 909932|Negativicutes L Terminase RNaseH-like domain - - - - - - - - - - - - - k59_81648_1 1126627.BAWE01000005_gene5331 3.37e-10 65.9 COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2TSCY@28211|Alphaproteobacteria,3JS0Q@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 k59_409949_2 1051675.G0YQI0_9CAUD 1.11e-160 479.0 4QF3C@10239|Viruses,4QWIA@35237|dsDNA viruses no RNA stage,4QU4U@28883|Caudovirales,4QNNQ@10744|Podoviridae 10744|Podoviridae S host cell wall - - - - - - - - - - - - - k59_307376_1 1244869.H261_11074 2.98e-57 218.0 COG4733@1|root,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria,2TV2W@28211|Alphaproteobacteria,2JV2T@204441|Rhodospirillales 204441|Rhodospirillales S COG4733 Phage-related protein, tail component - - - - - - - - - - - - Lambda_tail_I,Phage-tail_3 k59_2516_2 1327970.R9ZXR7_9CAUD 2.14e-61 199.0 4QAXN@10239|Viruses,4QVNW@35237|dsDNA viruses no RNA stage,4QPV1@28883|Caudovirales,4QM0D@10699|Siphoviridae 10699|Siphoviridae S D12 class N6 adenine-specific DNA methyltransferase - - - - - - - - - - - - - k59_2516_3 1123252.ATZF01000005_gene4125 1.46e-58 218.0 COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,4H9T3@91061|Bacilli,27BHW@186824|Thermoactinomycetaceae 91061|Bacilli L Helix-hairpin-helix motif dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k59_453850_1 1122201.AUAZ01000017_gene2950 9.15e-47 163.0 COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,1RY1X@1236|Gammaproteobacteria,46BED@72275|Alteromonadaceae 1236|Gammaproteobacteria S associated with various cellular activities - - - - - - - - - - - - AAA,AAA_5 k59_330914_4 1538804.A0A0A1CM43_9CAUD 8.09e-130 397.0 4QB5I@10239|Viruses,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_145905_1 620914.JH621275_gene418 8.78e-27 114.0 COG2273@1|root,COG5492@1|root,COG2273@2|Bacteria,COG5492@2|Bacteria,4NZUZ@976|Bacteroidetes,1I7XW@117743|Flavobacteriia 976|Bacteroidetes GN Cellulose Binding Domain Type IV - - - - - - - - - - - - Big_2,CBM_6 k59_535939_1 460265.Mnod_6992 8.04e-93 288.0 COG0270@1|root,COG0270@2|Bacteria,1MV9H@1224|Proteobacteria,2TTZG@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family dcm - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase,HTH_3,HTH_31 k59_638706_1 1234888.K0A2J2_9VIRU 9.71e-57 193.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_432812_5 136084.Q9G0H8_9CAUD 2.59e-05 57.8 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QNBD@10744|Podoviridae 10744|Podoviridae S outer membrane - - - - - - - - - - - - - k59_432812_9 1327977.S0A018_9CAUD 1.02e-09 72.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QNBD@10744|Podoviridae 10744|Podoviridae S outer membrane - - - - - - - - - - - - - k59_432812_10 910475.E5FFH1_9CAUD 0.000656 50.8 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QI82@10662|Myoviridae 10662|Myoviridae S virus tail, fiber - - - - - - - - - - - - - k59_432812_11 33035.JPJF01000033_gene2262 1.86e-14 84.3 28K55@1|root,2Z9TX@2|Bacteria,1V0P7@1239|Firmicutes,24DCX@186801|Clostridia,3Y0KI@572511|Blautia 186801|Clostridia S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - Sipho_Gp37 k59_412445_1 742821.HMPREF9464_01834 7.74e-37 140.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2VNHP@28216|Betaproteobacteria 28216|Betaproteobacteria S Terminase - - - - - - - - - - - - Terminase_1 k59_309332_1 742733.HMPREF9469_05034 0.000548 45.4 2EAAT@1|root,334F2@2|Bacteria,1VJJI@1239|Firmicutes,24TQU@186801|Clostridia,223KD@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_474631_1 929713.NIASO_17340 0.000308 50.1 COG3291@1|root,COG4409@1|root,COG3291@2|Bacteria,COG4409@2|Bacteria,4NGV7@976|Bacteroidetes 976|Bacteroidetes L PKD domain protein - - - - - - - - - - - - CarboxypepD_reg,Laminin_G_3,PKD,Peptidase_M14 k59_474631_3 1206741.BAFX01000172_gene7413 1.25e-34 124.0 2CICW@1|root,346YY@2|Bacteria,2HIJU@201174|Actinobacteria,4G48K@85025|Nocardiaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_535963_2 28444.JODQ01000009_gene3832 9.11e-19 82.4 COG0629@1|root,COG0629@2|Bacteria,2GMM3@201174|Actinobacteria,4EFMR@85012|Streptosporangiales 201174|Actinobacteria L Single-strand binding protein family ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_187097_2 1126885.I3VYX0_9CAUD 3.17e-34 131.0 4QG21@10239|Viruses,4QYV7@35237|dsDNA viruses no RNA stage,4QRQT@28883|Caudovirales,4QM3S@10699|Siphoviridae 10699|Siphoviridae S Phage terminase large subunit - - - - - - - - - - - - - k59_206979_2 1234888.K0A2J2_9VIRU 1.27e-73 240.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_433274_1 321332.CYB_1340 1.65e-19 86.7 COG0328@1|root,COG0328@2|Bacteria,1G12J@1117|Cyanobacteria,1GYK3@1129|Synechococcus 1117|Cyanobacteria L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhA - 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_H k59_166856_1 489825.LYNGBM3L_02700 3.22e-35 132.0 COG1403@1|root,COG1403@2|Bacteria,1G2XW@1117|Cyanobacteria,1H9Y3@1150|Oscillatoriales 1117|Cyanobacteria L HNH endonuclease domain protein - - - - - - - - - - - - HNH,HNH_5,RRXRR k59_519424_2 292459.STH3030 7.12e-25 98.6 COG1738@1|root,COG1738@2|Bacteria,1V8R2@1239|Firmicutes,24K5V@186801|Clostridia 186801|Clostridia S ACR, YhhQ family COG1738 - - - ko:K09125 - - - - ko00000 - - - Vut_1 k59_415558_4 1122175.ATXU01000009_gene1783 3.16e-26 103.0 2FJV8@1|root,34BHS@2|Bacteria,2GTIC@201174|Actinobacteria,4FT49@85023|Microbacteriaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_374816_1 1795983.A0A140CTJ3_9CIRC 8.85e-09 59.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_479483_1 1469607.KK073765_gene6586 1.88e-26 108.0 2CWXD@1|root,32T0J@2|Bacteria,1GAQJ@1117|Cyanobacteria,1HSA8@1161|Nostocales 1117|Cyanobacteria - - - - - - - - - - - - - - - k59_312409_2 1385935.N836_28775 4.42e-97 312.0 COG0433@1|root,COG0433@2|Bacteria,1G9M9@1117|Cyanobacteria,1HE23@1150|Oscillatoriales 1117|Cyanobacteria S AAA-like domain - - - - - - - - - - - - - k59_312409_3 575540.Isop_3669 5.72e-14 81.6 COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,2J1FN@203682|Planctomycetes 203682|Planctomycetes KL Belongs to the N(4) N(6)-methyltransferase family - - - - - - - - - - - - N6_N4_Mtase,ParBc k59_6230_1 591019.Shell_0107 0.000135 44.3 COG0863@1|root,arCOG00115@2157|Archaea,2XSS3@28889|Crenarchaeota 28889|Crenarchaeota L DNA methylase - - 2.1.1.113 ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_106920_1 1247726.MIM_c10960 7.87e-21 99.8 COG3096@1|root,COG5281@1|root,COG3096@2|Bacteria,COG5281@2|Bacteria,1MX2R@1224|Proteobacteria,2VIQC@28216|Betaproteobacteria,3T937@506|Alcaligenaceae 28216|Betaproteobacteria D tape measure - - - - - - - - - - - - Tape_meas_lam_C k59_67206_2 279530.Q6IWP7_9CAUD 1.07e-28 109.0 4QAQV@10239|Viruses,4QUPK@35237|dsDNA viruses no RNA stage,4QPCB@28883|Caudovirales 28883|Caudovirales S protein disulfide oxidoreductase activity - - - - - - - - - - - - - k59_540275_4 420324.KI911996_gene8012 3.52e-43 150.0 COG3772@1|root,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,2UE28@28211|Alphaproteobacteria,1JW5E@119045|Methylobacteriaceae 28211|Alphaproteobacteria G Phage lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_540275_12 1120977.JHUX01000003_gene794 5.83e-07 60.8 COG5281@1|root,COG5283@1|root,COG5281@2|Bacteria,COG5283@2|Bacteria,1QZFN@1224|Proteobacteria 1224|Proteobacteria D domain protein - - - - - - - - - - - - - k59_374850_2 395494.Galf_2026 6.43e-06 52.8 COG3170@1|root,COG3170@2|Bacteria 2|Bacteria NU translation initiation factor activity - - - - - - - - - - - - HP_OMP k59_579679_1 411460.RUMTOR_01356 1.72e-80 270.0 28JED@1|root,2Z98K@2|Bacteria,1TW1U@1239|Firmicutes,24CFD@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - GerE k59_353477_1 655097.C8ZKD3_9CAUD 4.13e-11 67.4 4QB3X@10239|Viruses,4QWKP@35237|dsDNA viruses no RNA stage,4QPEE@28883|Caudovirales,4QNCI@10744|Podoviridae 10744|Podoviridae S VWA-like domain (DUF2201) - - - - - - - - - - - - - k59_399306_1 1123277.KB893212_gene16 1.24e-45 174.0 COG1196@1|root,COG3941@1|root,COG1196@2|Bacteria,COG3941@2|Bacteria,4NS30@976|Bacteroidetes 976|Bacteroidetes D tape measure - - - - - - - - - - - - - k59_649496_1 1120971.AUCA01000053_gene370 5.76e-59 193.0 COG0553@1|root,COG0553@2|Bacteria,1TP2C@1239|Firmicutes,4HTYH@91061|Bacilli 91061|Bacilli KL DEAD-like helicases superfamily - - - - - - - - - - - - - k59_625795_1 643867.Ftrac_1402 6.47e-27 106.0 COG1961@1|root,COG1961@2|Bacteria 2|Bacteria L recombinase activity - - - ko:K06400 - - - - ko00000 - - - HTH_7,Recombinase,Resolvase,Zn_ribbon_recom k59_175023_3 1385658.U5KPZ6_9VIRU 1.05e-41 152.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_30080_1 444158.MmarC6_1417 6.73e-35 127.0 arCOG06669@1|root,arCOG06669@2157|Archaea,2XV2H@28890|Euryarchaeota,23RJC@183939|Methanococci 183939|Methanococci - - - - - - - - - - - - - - - k59_109719_2 1385658.U5KPZ6_9VIRU 5.64e-57 192.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_340775_1 1537917.JU82_00020 6.26e-52 170.0 COG0553@1|root,COG0553@2|Bacteria,1PM15@1224|Proteobacteria,42ZGS@68525|delta/epsilon subdivisions,2YS8B@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria L DEAD-like helicases superfamily - - - - - - - - - - - - - k59_356956_1 1692250.A0A0K1RLR1_9CIRC 5.34e-15 78.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_501912_2 1226322.HMPREF1545_02211 8.62e-16 79.0 2E9RM@1|root,333XV@2|Bacteria,1VSS6@1239|Firmicutes,25DZ3@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_30102_1 585425.KR52_03475 5.09e-13 69.7 29CPA@1|root,2ZZMJ@2|Bacteria 2|Bacteria S Domain of unknown function (DUF4338) - - - - - - - - - - - - DUF4338 k59_545963_1 1172188.KB911820_gene2847 1.17e-126 379.0 COG3567@1|root,COG3567@2|Bacteria,2H48H@201174|Actinobacteria 201174|Actinobacteria S Phage portal protein, SPP1 Gp6-like - - - - - - - - - - - - Phage_prot_Gp6 k59_650488_8 639030.JHVA01000001_gene234 6.63e-11 65.1 COG1028@1|root,COG1028@2|Bacteria,3Y2YB@57723|Acidobacteria,2JKGN@204432|Acidobacteriia 204432|Acidobacteriia IQ NAD dependent epimerase/dehydratase family - - - - - - - - - - - - adh_short_C2 k59_357502_1 555500.I215_14793 3.27e-48 166.0 COG0675@1|root,COG0675@2|Bacteria,4NQSI@976|Bacteroidetes 976|Bacteroidetes L Transposase, IS605 OrfB family - - - - - - - - - - - - - k59_546939_1 511437.Lbuc_1541 8e-40 145.0 2CWXD@1|root,32T0J@2|Bacteria,1V83I@1239|Firmicutes,4HPQE@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k59_491382_7 1157490.EL26_01805 7.2e-56 198.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4H9YP@91061|Bacilli,2791R@186823|Alicyclobacillaceae 91061|Bacilli KL SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,SNF2_N k59_655782_2 1692252.A0A0K1RL35_9CIRC 2.19e-78 248.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_424811_1 497965.Cyan7822_1959 8.87e-50 171.0 COG0675@1|root,COG0675@2|Bacteria,1G01E@1117|Cyanobacteria,3KHKD@43988|Cyanothece 1117|Cyanobacteria L TIGRFAM transposase, IS605 OrfB family - - - ko:K07496 - - - - ko00000 - - - HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon k59_506444_1 365659.smi_1090 0.000212 50.4 COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,1TPSU@1239|Firmicutes,4HB12@91061|Bacilli,2TP9M@28037|Streptococcus mitis 91061|Bacilli L UvrD/REP helicase N-terminal domain - - - - - - - - - - - - PDDEXK_1,UvrD-helicase,UvrD_C k59_280595_1 236097.ADG881_730 7.55e-15 79.3 COG1793@1|root,COG1793@2|Bacteria,1MUW3@1224|Proteobacteria,1S2JP@1236|Gammaproteobacteria,1XJ7T@135619|Oceanospirillales 135619|Oceanospirillales L DNA ligase - - 6.5.1.1,6.5.1.6,6.5.1.7 ko:K10747 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00381,R00382,R10822,R10823 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - DNA_ligase_A_M,DNA_ligase_OB_2 k59_384193_1 1476391.X5KCE1_9CAUD 3.39e-78 255.0 4QF3C@10239|Viruses,4QWIA@35237|dsDNA viruses no RNA stage,4QU4U@28883|Caudovirales,4QNNQ@10744|Podoviridae 10744|Podoviridae S host cell wall - - - - - - - - - - - - - k59_655841_1 1123009.AUID01000045_gene1202 1.61e-63 205.0 2E1MQ@1|root,32WYT@2|Bacteria,1VB8R@1239|Firmicutes,24R84@186801|Clostridia,269J6@186813|unclassified Clostridiales 186801|Clostridia - - - - - - - - - - - - - - - k59_384196_1 1121286.AUMT01000022_gene1687 0.000359 48.1 2F8FG@1|root,340U7@2|Bacteria,4P45X@976|Bacteroidetes,1I9YA@117743|Flavobacteriia,3ZSXJ@59732|Chryseobacterium 976|Bacteroidetes - - - - - - - - - - - - - - - k59_76071_2 102129.Lepto7375DRAFT_7192 1.37e-15 84.7 COG0467@1|root,COG1467@1|root,COG0467@2|Bacteria,COG1467@2|Bacteria 2|Bacteria L DNA replication initiation - - - - - - - - - - - - AAA_11,AAA_12,AAA_25,DUF3320,DUF3987,DUF4011 k59_139258_1 1521187.JPIM01000114_gene1936 2.9e-68 227.0 COG0504@1|root,COG0504@2|Bacteria,2G5U0@200795|Chloroflexi,376WB@32061|Chloroflexia 32061|Chloroflexia F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG - 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - - CTP_synth_N,GATase k59_101284_1 265072.Mfla_2685 2.83e-23 111.0 COG4733@1|root,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria,2VJEP@28216|Betaproteobacteria 28216|Betaproteobacteria NT Phage-related protein, tail - - - - - - - - - - - - DUF1983,Phage-tail_3 k59_223346_1 1051675.G0YQC7_9CAUD 2.94e-27 110.0 4QAR1@10239|Viruses,4QUNA@35237|dsDNA viruses no RNA stage,4QPJE@28883|Caudovirales,4QNDS@10744|Podoviridae 10744|Podoviridae S ATPase activity - - - - - - - - - - - - - k59_245597_2 145579.CAPSD_BPPHM 2.99e-50 175.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_614667_1 1120985.AUMI01000001_gene2164 1.56e-13 78.2 COG5281@1|root,COG5281@2|Bacteria,1TPWF@1239|Firmicutes,4H3NF@909932|Negativicutes 909932|Negativicutes S tape measure - - - - - - - - - - - - - k59_223394_1 589865.DaAHT2_0649 1.34e-05 50.1 COG2203@1|root,COG2203@2|Bacteria 2|Bacteria T Gaf domain - - - - - - - - - - - - GAF,GAF_2,GGDEF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg k59_223430_2 1385658.U5KQQ9_9VIRU 7.99e-12 70.1 4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_614875_1 391595.RLO149_c000590 0.000333 50.8 COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,2P437@2433|Roseobacter 28211|Alphaproteobacteria Q Laminin G domain - - 3.4.24.40 ko:K01406 ko01503,map01503 - - - ko00000,ko00001,ko01000,ko01002 - - - CBM60,HemolysinCabind,Laminin_G_3,Metallophos,PPC,Peptidase_M10_C k59_163247_1 406327.Mevan_0570 8.2e-24 95.9 arCOG06669@1|root,arCOG06669@2157|Archaea,2XV2H@28890|Euryarchaeota,23RJC@183939|Methanococci 183939|Methanococci - - - - - - - - - - - - - - - k59_163264_1 691965.D4P7D6_9CAUD 1.35e-47 175.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_163276_1 1187128.I2GUC6_9CAUD 1.77e-40 146.0 4QBHW@10239|Viruses,4QW8N@35237|dsDNA viruses no RNA stage,4QTT7@28883|Caudovirales,4QJZQ@10662|Myoviridae 10662|Myoviridae S sequence-specific DNA binding transcription factor activity - - - - - - - - - - - - - k59_223515_4 1348663.KCH_25590 3.89e-43 180.0 COG4733@1|root,COG4733@2|Bacteria,2ID73@201174|Actinobacteria 201174|Actinobacteria S cellulase activity - - - - - - - - - - - - - k59_120876_1 411462.DORLON_00791 3.73e-33 124.0 2CWXD@1|root,32T0J@2|Bacteria,1V83I@1239|Firmicutes,25DQF@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - AP2 k59_225542_4 1165094.RINTHH_3920 6.4e-75 239.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_225542_6 105154.Q9MBU6_9VIRU 9.77e-222 631.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_225542_7 105154.Q9MBU3_9VIRU 1.1e-14 75.1 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_61120_1 279303.Q6J827_9CAUD 3.73e-34 140.0 4QBSP@10239|Viruses,4QZ8J@35237|dsDNA viruses no RNA stage,4QRAT@28883|Caudovirales,4QM0N@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_61196_1 1122214.AQWH01000019_gene3406 7.67e-31 129.0 COG5280@1|root,COG5280@2|Bacteria 2|Bacteria NT Phage tail tape measure protein TP901 yqbO5 - - - - - - - - - - - PhageMin_Tail,SLT k59_412980_2 670307.HYPDE_23438 3.13e-12 73.9 COG2327@1|root,COG2327@2|Bacteria,1N1VM@1224|Proteobacteria,2UTMS@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Polysaccharide pyruvyl transferase - - - - - - - - - - - - PS_pyruv_trans k59_249463_3 574087.Acear_1218 4.64e-30 114.0 arCOG06669@1|root,2ZC1E@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_85319_1 9361.ENSDNOP00000009689 2.09e-06 55.5 COG0553@1|root,KOG1000@2759|Eukaryota,38C05@33154|Opisthokonta,3BE0M@33208|Metazoa,3CT9F@33213|Bilateria,4833X@7711|Chordata,4986G@7742|Vertebrata,3J96H@40674|Mammalia 33208|Metazoa B annealing helicase activity SMARCAL1 GO:0000278,GO:0000723,GO:0000724,GO:0000725,GO:0000726,GO:0000733,GO:0001325,GO:0001501,GO:0001525,GO:0001568,GO:0001944,GO:0002376,GO:0002520,GO:0003674,GO:0003676,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005700,GO:0005705,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006302,GO:0006310,GO:0006355,GO:0006357,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007049,GO:0007275,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009378,GO:0009653,GO:0009790,GO:0009888,GO:0009889,GO:0009987,GO:0010171,GO:0010172,GO:0010468,GO:0010556,GO:0010709,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030097,GO:0030491,GO:0031297,GO:0031323,GO:0031326,GO:0031974,GO:0031981,GO:0032200,GO:0032392,GO:0032501,GO:0032502,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0035239,GO:0035295,GO:0035861,GO:0036292,GO:0036310,GO:0040007,GO:0042592,GO:0042623,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044464,GO:0045002,GO:0045003,GO:0045005,GO:0046483,GO:0048513,GO:0048514,GO:0048534,GO:0048589,GO:0048598,GO:0048646,GO:0048731,GO:0048856,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051216,GO:0051252,GO:0051276,GO:0051716,GO:0060249,GO:0060255,GO:0061306,GO:0061448,GO:0065007,GO:0065008,GO:0070013,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0072358,GO:0072359,GO:0080090,GO:0090304,GO:0090656,GO:0090734,GO:0090737,GO:0097159,GO:0097617,GO:0098687,GO:0140097,GO:1901360,GO:1901363,GO:1901576,GO:1903506,GO:1990163,GO:2000112,GO:2001141 3.6.4.12 ko:K14440 - - - - ko00000,ko01000,ko03036 - - - HARP,Helicase_C,SNF2_N k59_23318_2 862515.HMPREF0658_1276 1.6e-37 159.0 COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,4NMBI@976|Bacteroidetes,2FR6N@200643|Bacteroidia 976|Bacteroidetes D nuclear chromosome segregation - - - - - - - - - - - - - k59_146506_1 1234888.K0A2J2_9VIRU 8.44e-143 424.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_475371_3 1618247.A0A0C5IMK7_9CIRC 2.13e-06 54.7 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_64319_1 946362.XP_004995355.1 5.73e-53 188.0 COG1372@1|root,2QRRC@2759|Eukaryota,39SG8@33154|Opisthokonta 33154|Opisthokonta L reductase - - - - - - - - - - - - Ribonuc_red_lgC k59_249481_1 888059.HMPREF9071_1492 2.95e-26 111.0 COG0305@1|root,COG0305@2|Bacteria,4NF8P@976|Bacteroidetes,1HWS1@117743|Flavobacteriia,1EQN3@1016|Capnocytophaga 976|Bacteroidetes L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_413008_1 1520935.A0A0H3UB63_9CIRC 6.73e-42 151.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_167551_1 1286171.EAL2_c21930 6.71e-14 74.7 COG0739@1|root,COG3583@1|root,COG0739@2|Bacteria,COG3583@2|Bacteria,1TRWJ@1239|Firmicutes,24A2J@186801|Clostridia,25X5A@186806|Eubacteriaceae 186801|Clostridia M COG0739 Membrane proteins related to metalloendopeptidases - - - - - - - - - - - - G5,LysM,Peptidase_M23 k59_577682_1 1131730.BAVI_14074 2.85e-23 111.0 COG4373@1|root,COG4373@2|Bacteria,1TQNK@1239|Firmicutes,4HDES@91061|Bacilli,1ZBVH@1386|Bacillus 91061|Bacilli S Mu-like prophage FluMu protein gp28 gp17a - - - - - - - - - - - Terminase_6,Terminase_6C k59_310407_1 1038860.AXAP01000067_gene8427 7.73e-50 175.0 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,2U6BJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S TIGRFAM phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_167557_1 41431.PCC8801_3900 1.38e-29 112.0 COG1943@1|root,COG1943@2|Bacteria,1G603@1117|Cyanobacteria,3KI97@43988|Cyanothece 1117|Cyanobacteria L PFAM transposase IS200-family protein - - - ko:K07491 - - - - ko00000 - - - Y1_Tnp k59_557069_2 101510.RHA1_ro06566 6.1e-36 128.0 2DRAR@1|root,33AZK@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_537599_1 1123279.ATUS01000005_gene3101 1.43e-42 159.0 COG4653@1|root,COG4653@2|Bacteria,1MYMH@1224|Proteobacteria,1RR5E@1236|Gammaproteobacteria 1236|Gammaproteobacteria S capsid protein - - - - - - - - - - - - Phage_capsid k59_537599_2 742821.HMPREF9464_01832 1.25e-38 140.0 COG3740@1|root,COG3740@2|Bacteria,1N2D8@1224|Proteobacteria,2VX9U@28216|Betaproteobacteria 28216|Betaproteobacteria S Caudovirus prohead serine protease - - - ko:K06904 - - - - ko00000 - - - Peptidase_S78 k59_8487_1 1234888.K0A2J2_9VIRU 3.37e-33 129.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_69398_1 556268.OFAG_00835 6.34e-41 155.0 COG2963@1|root,COG2963@2|Bacteria,1PCWW@1224|Proteobacteria,2VKXF@28216|Betaproteobacteria,47377@75682|Oxalobacteraceae 28216|Betaproteobacteria L transposase activity - - - - - - - - - - - - - k59_314145_7 1122973.KB904281_gene1062 3.96e-56 179.0 COG0720@1|root,COG0720@2|Bacteria,4PIUG@976|Bacteroidetes,2FSF1@200643|Bacteroidia,22Z05@171551|Porphyromonadaceae 976|Bacteroidetes H 6-pyruvoyl tetrahydrobiopterin synthase queD - 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 - - - PTPS k59_314145_8 1538804.A0A088FAQ4_9CAUD 1.8e-50 171.0 4QCT7@10239|Viruses,4QPFU@28883|Caudovirales,4QKS9@10699|Siphoviridae 10699|Siphoviridae S iron-sulfur cluster binding - - - - - - - - - - - - - k59_314145_9 533240.CRC_00931 1.52e-47 166.0 COG0302@1|root,COG0302@2|Bacteria,1G1K8@1117|Cyanobacteria,1HIXJ@1161|Nostocales 1117|Cyanobacteria H PFAM GTP cyclohydrolase I folE GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - iECNA114_1301.folE,iJN678.folE GTP_cyclohydroI k59_274017_1 6326.BUX.s01078.185 2.6e-11 70.9 COG5271@1|root,KOG1808@2759|Eukaryota,38FBP@33154|Opisthokonta,3BD9P@33208|Metazoa,3CUCR@33213|Bilateria,40ATB@6231|Nematoda,1KUCP@119089|Chromadorea 33208|Metazoa S Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits mdn1 - - ko:K14572 ko03008,map03008 - - - ko00000,ko00001,ko03009 - - - AAA_5,VWA_2 k59_482222_1 265072.Mfla_2685 2.09e-20 104.0 COG4733@1|root,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria,2VJEP@28216|Betaproteobacteria 28216|Betaproteobacteria NT Phage-related protein, tail - - - - - - - - - - - - DUF1983,Phage-tail_3 k59_172660_3 391037.Sare_1514 2.01e-13 66.6 2EMZM@1|root,33FMT@2|Bacteria,2GYG9@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_27948_3 1144313.PMI10_00498 5.92e-11 63.2 COG1196@1|root,COG1196@2|Bacteria,4PFK2@976|Bacteroidetes,1I7AN@117743|Flavobacteriia 976|Bacteroidetes D nuclear chromosome segregation - - - - - - - - - - - - AAA_23 k59_69418_2 1572239.A0A0A0YP18_9CIRC 1.34e-06 56.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_337841_1 1231377.C426_0487 1.26e-45 159.0 COG1470@1|root,COG1470@2|Bacteria,1TRGE@1239|Firmicutes,4HBPI@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF3048) C-terminal domain yerB - - - - - - - - - - - DUF3048,DUF3048_C k59_344597_1 579138.Zymop_0145 1.04e-30 117.0 COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,2TTVJ@28211|Alphaproteobacteria,2K0JM@204457|Sphingomonadales 204457|Sphingomonadales I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids uppS - 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf k59_344597_2 553973.CLOHYLEM_06493 5.47e-05 45.8 COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,247MT@186801|Clostridia,21XP2@1506553|Lachnoclostridium 186801|Clostridia M zinc metalloprotease rseP - - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_M50 k59_504759_2 861208.AGROH133_06202 3.18e-19 88.6 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2TSDW@28211|Alphaproteobacteria,4BCQ8@82115|Rhizobiaceae 28211|Alphaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_629468_5 1217705.F900_02095 2.24e-20 87.4 COG3772@1|root,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,1S99W@1236|Gammaproteobacteria,3NKTC@468|Moraxellaceae 1236|Gammaproteobacteria G Phage lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_345434_1 264732.Moth_0002 2.05e-49 175.0 COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,2490S@186801|Clostridia,42F49@68295|Thermoanaerobacterales 186801|Clostridia L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA - - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N k59_530681_1 1236514.BAKL01000134_gene5619 1.98e-26 125.0 COG5283@1|root,COG5283@2|Bacteria,4NG54@976|Bacteroidetes,2FN2V@200643|Bacteroidia,4ANSK@815|Bacteroidaceae 976|Bacteroidetes S Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_530681_2 1348663.KCH_26220 3.93e-73 245.0 COG5323@1|root,COG5362@1|root,COG5410@1|root,COG5323@2|Bacteria,COG5362@2|Bacteria,COG5410@2|Bacteria,2I1XF@201174|Actinobacteria,2M5NQ@2063|Kitasatospora 201174|Actinobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6 k59_530681_4 1087481.AGFX01000039_gene1478 2.02e-77 254.0 COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,1TPHP@1239|Firmicutes,4HC9M@91061|Bacilli,26TY2@186822|Paenibacillaceae 91061|Bacilli KL DNA methylase - - - - - - - - - - - - N6_N4_Mtase,ParBc k59_99546_1 411460.RUMTOR_01350 6.29e-08 55.1 2EAAT@1|root,334F2@2|Bacteria,1VJJI@1239|Firmicutes,24TQU@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_14447_1 679197.HMPREF9336_00431 1.74e-06 58.5 COG3378@1|root,COG3378@2|Bacteria,2GQQM@201174|Actinobacteria 201174|Actinobacteria S Phage plasmid primase P4 family - - - - - - - - - - - - D5_N k59_505331_1 1071679.BG57_03870 4.21e-14 80.5 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2VNHP@28216|Betaproteobacteria,1K7BW@119060|Burkholderiaceae 28216|Betaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_608092_1 1388763.O165_022250 9.44e-68 226.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria 1224|Proteobacteria K Terminase - - - - - - - - - - - - Terminase_1 k59_608092_3 504346.PRO_0000326456 3.28e-20 99.4 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales 28883|Caudovirales S N-acetylmuramoyl-L-alanine amidase activity - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019028,GO:0019058,GO:0019062,GO:0022610,GO:0042802,GO:0044403,GO:0044406,GO:0044419,GO:0044423,GO:0044650,GO:0051704,GO:0098015,GO:0098024 - - - - - - - - - - - k59_608092_5 329254.Q2NPI6_9CAUD 1.41e-11 74.7 4QAYV@10239|Viruses,4QUZ7@35237|dsDNA viruses no RNA stage,4QPU3@28883|Caudovirales,4QKKX@10699|Siphoviridae 10699|Siphoviridae S Phage portal protein - - - - - - - - - - - - - k59_490298_2 105154.Q9MBU6_9VIRU 4.74e-109 335.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_466014_1 547559.Nmag_0757 9.43e-10 60.8 arCOG11413@1|root,arCOG11413@2157|Archaea,2XWQW@28890|Euryarchaeota,23VBV@183963|Halobacteria 183963|Halobacteria S T4-like virus tail tube protein gp19 - - - - - - - - - - - - Phage_T4_gp19 k59_466014_2 1005048.CFU_2035 1.8e-11 65.1 COG3497@1|root,COG3497@2|Bacteria,1MX89@1224|Proteobacteria,2VM4U@28216|Betaproteobacteria,4771I@75682|Oxalobacteraceae 28216|Betaproteobacteria S Phage tail sheath C-terminal domain - - - ko:K06907 - - - - ko00000 - - - Phage_sheath_1,Phage_sheath_1C k59_382980_1 984262.SGRA_2540 2.37e-24 97.4 COG0629@1|root,COG0629@2|Bacteria,4PGRJ@976|Bacteroidetes,1IU5E@117747|Sphingobacteriia 976|Bacteroidetes L Domain of unknown function (DUF3127) - - - - - - - - - - - - DUF3127 k59_81103_3 1618247.A0A0C5I2K0_9CIRC 4.4e-45 164.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_306776_1 28115.HR11_07040 1.86e-68 233.0 COG0305@1|root,COG0305@2|Bacteria,4NF8P@976|Bacteroidetes,2FNG7@200643|Bacteroidia,22XCZ@171551|Porphyromonadaceae 976|Bacteroidetes L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_40408_1 1120936.KB907208_gene1108 1.6e-59 196.0 COG0468@1|root,COG0468@2|Bacteria,2GJ4P@201174|Actinobacteria,4EGN4@85012|Streptosporangiales 201174|Actinobacteria L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage - - - - - - - - - - - - RecA k59_306865_1 1236976.JCM16418_4619 2.41e-29 117.0 COG1876@1|root,COG1876@2|Bacteria,1V1F7@1239|Firmicutes,4HG3S@91061|Bacilli,274A7@186822|Paenibacillaceae 91061|Bacilli M D-alanyl-D-alanine carboxypeptidase - - 3.4.17.14 ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 M00651 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 - - - VanY k59_593979_1 639283.Snov_3140 1.34e-24 105.0 COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,2TREC@28211|Alphaproteobacteria,3EXYW@335928|Xanthobacteraceae 28211|Alphaproteobacteria F Cell wall formation ddl - 1.3.1.98,6.3.2.4 ko:K00075,ko:K01921 ko00473,ko00520,ko00550,ko01100,ko01502,map00473,map00520,map00550,map01100,map01502 - R01150,R03191,R03192 RC00064,RC00141,RC02639 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N k59_365662_1 1238186.AOCN01000011_gene1388 7.35e-12 73.9 COG2755@1|root,COG3291@1|root,COG2755@2|Bacteria,COG3291@2|Bacteria,2I8JW@201174|Actinobacteria,4FPT9@85023|Microbacteriaceae 201174|Actinobacteria E GDSL-like Lipase/Acylhydrolase family - - - - - - - - - - - - Lipase_GDSL_2 k59_306891_1 1051675.G0YQF5_9CAUD 1.37e-49 184.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_244348_1 634176.NT05HA_0494 6.5e-73 235.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,1TKGR@1236|Gammaproteobacteria,1Y7SY@135625|Pasteurellales 135625|Pasteurellales S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_59931_1 1333856.L686_18255 2.37e-12 73.2 COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,1RMJ1@1236|Gammaproteobacteria,1Z2PJ@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria L phage integrase family - - - - - - - - - - - - Arm-DNA-bind_3,Phage_integrase k59_187005_1 646529.Desaci_1283 3.72e-12 72.0 COG0417@1|root,COG0417@2|Bacteria,1TQJQ@1239|Firmicutes,24AUM@186801|Clostridia 186801|Clostridia L DNA polymerase elongation subunit (Family B) - - - - - - - - - - - - - k59_475084_1 1234888.K0A2J2_9VIRU 3.97e-77 249.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_639107_4 768066.HELO_4194 5.11e-16 88.6 COG3378@1|root,COG3378@2|Bacteria,1QVIS@1224|Proteobacteria,1S02S@1236|Gammaproteobacteria,1XP9I@135619|Oceanospirillales 135619|Oceanospirillales S Phage plasmid primase P4 family - - - ko:K06919 - - - - ko00000 - - - - k59_412815_1 1151292.QEW_2423 1.86e-23 112.0 COG3941@1|root,COG5412@1|root,COG3941@2|Bacteria,COG5412@2|Bacteria,1TQDE@1239|Firmicutes,249I0@186801|Clostridia,25T13@186804|Peptostreptococcaceae 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_536538_1 767817.Desgi_1033 1.65e-37 151.0 COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,2605R@186807|Peptococcaceae 186801|Clostridia L DNA polymerase III alpha subunit dnaE - 2.7.7.7 ko:K02337,ko:K14162 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k59_125684_1 2003327.CAPSD_BPCHP 2.77e-14 79.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_166911_1 186617.M9M8L2_9VIRU 3.68e-57 191.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_269395_2 298654.FraEuI1c_7007 0.000357 49.7 COG1442@1|root,COG1442@2|Bacteria 2|Bacteria M lipopolysaccharide 3-alpha-galactosyltransferase activity yfnF - - - - - - - - - - - GT-D,Glyco_transf_8 k59_125692_1 691965.D4P7D6_9CAUD 2.99e-118 367.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_309709_1 272560.BPSL0146 0.000767 48.1 COG4942@1|root,COG4942@2|Bacteria,1QTW5@1224|Proteobacteria,2WGFW@28216|Betaproteobacteria,1K552@119060|Burkholderiaceae 28216|Betaproteobacteria D peptidase - - - - - - - - - - - - - k59_228009_1 10855.CAPSD_SPV4 3.21e-21 100.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_104688_3 44088.Q6VZJ4_CNPV 5.62e-34 133.0 4QB1C@10239|Viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_187458_1 1611039.A0A0C5C3Z3_9CIRC 3.16e-27 110.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_371704_2 1618256.A0A0C5IM93_9CIRC 1.13e-66 217.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_125714_1 1244869.H261_10894 2.48e-86 271.0 COG0270@1|root,COG0270@2|Bacteria,1MV9H@1224|Proteobacteria,2U64S@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_475162_2 1321782.HMPREF1986_02255 1.31e-87 277.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,2PRYV@265975|Oribacterium 186801|Clostridia L SNF2 family N-terminal domain - - - - - - - - - - - - SNF2_N k59_249284_1 1788454.A0A190WHE4_9CIRC 1.17e-43 155.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_392399_3 1038860.AXAP01000067_gene8427 5.34e-67 227.0 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,2U6BJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S TIGRFAM phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_645056_1 1297534.CAUJ01000005_gene180 3.64e-07 55.5 COG3740@1|root,COG3740@2|Bacteria 2|Bacteria OU Phage prohead protease, HK97 family - - - ko:K06904 - - - - ko00000 - - - Peptidase_S78 k59_231781_3 1121100.JCM6294_1074 1.57e-147 427.0 COG0270@1|root,COG0270@2|Bacteria,4P3IR@976|Bacteroidetes,2FN10@200643|Bacteroidia,4AN47@815|Bacteroidaceae 976|Bacteroidetes H C-5 cytosine-specific DNA methylase - - - - - - - - - - - - DNA_methylase k59_541902_2 1618237.A0A0C5IMG6_9CIRC 2.02e-40 149.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_581049_1 1116369.KB890024_gene2035 1.69e-11 68.9 COG1215@1|root,COG3774@1|root,COG1215@2|Bacteria,COG3774@2|Bacteria,1PG7X@1224|Proteobacteria,2VE3G@28211|Alphaproteobacteria,43MWG@69277|Phyllobacteriaceae 28211|Alphaproteobacteria M Anp1 - - - - - - - - - - - - Anp1,Gly_transf_sug k59_645100_2 329381.D9ICQ3_9CAUD 2.01e-14 78.2 4QAKE@10239|Viruses,4QUP7@35237|dsDNA viruses no RNA stage,4QPCE@28883|Caudovirales,4QI56@10662|Myoviridae 10662|Myoviridae S nucleic acid binding - - - - - - - - - - - - - k59_294268_1 1352230.S6B1J7_9CAUD 0.000632 47.8 4QB4T@10239|Viruses,4QVRD@35237|dsDNA viruses no RNA stage 10239|Viruses - - - - - - - - - - - - - - - k59_459282_6 1196083.SALWKB12_2039 3.14e-07 50.4 COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,2VU2J@28216|Betaproteobacteria,2KS2I@206351|Neisseriales 206351|Neisseriales O Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins grxC - - ko:K03676 - - - - ko00000,ko03110 - - - Glutaredoxin k59_560770_1 105154.Q9MBU3_9VIRU 8.79e-08 57.4 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_560770_2 1385658.U5KPZ6_9VIRU 1.24e-140 417.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_645854_2 1123377.AUIV01000026_gene579 5.81e-21 95.9 COG4983@1|root,COG4983@2|Bacteria,1N636@1224|Proteobacteria,1RZVN@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Protein of unknown function (DUF3987) - - - - - - - - - - - - DUF3987 k59_396731_1 10752.A0MZC7_BPN4 6.79e-13 74.3 4QBY0@10239|Viruses,4QW35@35237|dsDNA viruses no RNA stage,4QQ4Q@28883|Caudovirales,4QNNN@10744|Podoviridae 10744|Podoviridae S UvrD-like helicase C-terminal domain - - - - - - - - - - - - - k59_359019_1 1197951.I6R9K8_9CAUD 4.89e-20 87.8 4QFIC@10239|Viruses,4QXG2@35237|dsDNA viruses no RNA stage,4QTVA@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_401662_1 942016.E9NIF9_9CAUD 3.51e-25 108.0 4QB3X@10239|Viruses,4QWKP@35237|dsDNA viruses no RNA stage,4QPEE@28883|Caudovirales,4QNCI@10744|Podoviridae 10744|Podoviridae S VWA-like domain (DUF2201) - - - - - - - - - - - - - k59_381733_1 76114.ebA532 1.15e-52 181.0 COG1961@1|root,COG1961@2|Bacteria,1MV0C@1224|Proteobacteria,2VPTV@28216|Betaproteobacteria,2KZ7S@206389|Rhodocyclales 206389|Rhodocyclales L Recombinase - - - - - - - - - - - - Recombinase,Resolvase k59_318861_1 1187128.I2GUC6_9CAUD 4.16e-39 142.0 4QBHW@10239|Viruses,4QW8N@35237|dsDNA viruses no RNA stage,4QTT7@28883|Caudovirales,4QJZQ@10662|Myoviridae 10662|Myoviridae S sequence-specific DNA binding transcription factor activity - - - - - - - - - - - - - k59_359021_2 765910.MARPU_05580 1.25e-105 323.0 COG3723@1|root,COG3723@2|Bacteria,1R6DB@1224|Proteobacteria,1RZZ3@1236|Gammaproteobacteria 1236|Gammaproteobacteria L COG3723 Recombinational DNA repair protein (RecE pathway) recT GO:0000724,GO:0000725,GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0018130,GO:0019438,GO:0032392,GO:0032508,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043150,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071704,GO:0071840,GO:0071897,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - ko:K07455 - - - - ko00000,ko03400 - - - RecT k59_504322_1 1265502.KB905983_gene551 4.15e-05 50.8 28KRA@1|root,2ZA8W@2|Bacteria,1R7WX@1224|Proteobacteria,2W0N1@28216|Betaproteobacteria 1265502.KB905983_gene551|- - - - - - - - - - - - - - - - k59_214848_1 269798.CHU_3266 4.92e-14 72.0 COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,4NIIR@976|Bacteroidetes,47UJ0@768503|Cytophagia 976|Bacteroidetes L Exodeoxyribonuclease V, gamma subunit - - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C k59_196904_1 291607.MREP_SCSVF 1.08e-09 61.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_236871_2 759938.F5BSB4_9CIRC 4.11e-33 127.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_13250_1 1461579.CCNK01000042_gene2127 1.41e-08 60.5 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RM7S@1236|Gammaproteobacteria,1Y70U@135625|Pasteurellales 135625|Pasteurellales M Membrane proteins related to metalloendopeptidases Z012_08405 - - - - - - - - - - - OapA,Peptidase_M23 k59_178014_1 767817.Desgi_2098 1.15e-22 99.8 COG0046@1|root,COG0046@2|Bacteria,1TPAS@1239|Firmicutes,247W2@186801|Clostridia,260FM@186807|Peptococcaceae 186801|Clostridia F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purL - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C,GATase_5 k59_214854_1 888439.HMPREF9240_01630 0.000768 48.9 COG1132@1|root,COG1132@2|Bacteria,2IB0X@201174|Actinobacteria,4D3HK@85005|Actinomycetales 201174|Actinobacteria V ABC transporter, ATP-binding protein - - - ko:K06147,ko:K06148 - - - - ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k59_51446_1 1556290.A0A0A0RL96_9CAUD 1.21e-108 332.0 4QGMJ@10239|Viruses,4QSYG@28883|Caudovirales,4QM5B@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_364379_2 880070.Cycma_2357 3.85e-08 52.4 2A7X2@1|root,30WWV@2|Bacteria,4PA9D@976|Bacteroidetes,47SZW@768503|Cytophagia 976|Bacteroidetes S Helix-turn-helix domain - - - - - - - - - - - - HTH_17 k59_389033_2 1091052.I0J2R0_9CAUD 1.64e-06 54.7 4QAKE@10239|Viruses,4QUP7@35237|dsDNA viruses no RNA stage,4QPCE@28883|Caudovirales,4QI56@10662|Myoviridae 10662|Myoviridae S nucleic acid binding - - - - - - - - - - - - - k59_612289_1 391008.Smal_0903 9.96e-25 111.0 COG4643@1|root,COG5545@1|root,COG4643@2|Bacteria,COG5545@2|Bacteria,1MVGK@1224|Proteobacteria,1SAWT@1236|Gammaproteobacteria,1XBW3@135614|Xanthomonadales 135614|Xanthomonadales S Virulence-associated protein E - - - ko:K06919 - - - - ko00000 - - - VirE k59_634885_1 1460634.JCM19037_4377 2.53e-20 87.0 2DQBA@1|root,335SB@2|Bacteria,1VHD4@1239|Firmicutes,4HPCE@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k59_510382_1 1123326.JFBL01000001_gene1382 0.000177 49.3 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42TH4@68525|delta/epsilon subdivisions,2YRFX@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria T GHKL domain - - - - - - - - - - - - HATPase_c,PAS_3 k59_40064_1 691965.D4P7I3_9CAUD 5.99e-53 188.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_243975_3 655097.C8ZKI1_9CAUD 2.25e-18 87.8 4QF3C@10239|Viruses,4QWIA@35237|dsDNA viruses no RNA stage,4QU4U@28883|Caudovirales,4QNNQ@10744|Podoviridae 10744|Podoviridae S host cell wall - - - - - - - - - - - - - k59_365305_1 1255043.TVNIR_2104 4.27e-65 215.0 COG0305@1|root,COG0305@2|Bacteria 2|Bacteria L Participates in initiation and elongation during chromosome replication - - 3.6.4.12 ko:K02314,ko:K17680 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03029,ko03032 - - - AAA_25,DUF3987,DnaB k59_306537_3 1121422.AUMW01000060_gene85 4.7e-15 83.6 COG1475@1|root,COG1475@2|Bacteria,1UF7N@1239|Firmicutes,24URT@186801|Clostridia 186801|Clostridia K DNA binding - - - - - - - - - - - - HTH_23,ParBc k59_430345_1 10752.A0MZC9_BPN4 1.73e-69 241.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_430345_2 1173762.S4TP25_9CAUD 3.27e-142 432.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_430345_3 1416009.V9VCX5_9CAUD 6.46e-79 251.0 4QEG2@10239|Viruses,4QVSD@35237|dsDNA viruses no RNA stage,4QRJ9@28883|Caudovirales,4QP0R@10744|Podoviridae 10744|Podoviridae S exonuclease activity - - - - - - - - - - - - - k59_430345_5 655097.C8ZKG2_9CAUD 5.47e-59 203.0 4QGA5@10239|Viruses,4QURD@35237|dsDNA viruses no RNA stage,4QT9N@28883|Caudovirales,4QP47@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_57596_1 55529.EKX49673 1.66e-05 53.9 COG0086@1|root,KOG0260@2759|Eukaryota 2759|Eukaryota K DNA-directed 5'-3' RNA polymerase activity - - 2.7.7.6 ko:K03006 ko00230,ko00240,ko01100,ko03020,ko05016,ko05168,ko05169,map00230,map00240,map01100,map03020,map05016,map05168,map05169 M00180 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5,RNA_pol_Rpb1_6,RNA_pol_Rpb1_7 k59_326982_1 1139219.I569_00086 8.28e-15 75.1 COG3740@1|root,COG3740@2|Bacteria,1VH0Q@1239|Firmicutes,4HZC1@91061|Bacilli 91061|Bacilli S Caudovirus prohead serine protease - - - - - - - - - - - - Peptidase_S78 k59_326982_2 329381.D9ICQ3_9CAUD 5.99e-13 75.5 4QAKE@10239|Viruses,4QUP7@35237|dsDNA viruses no RNA stage,4QPCE@28883|Caudovirales,4QI56@10662|Myoviridae 10662|Myoviridae S nucleic acid binding - - - - - - - - - - - - - k59_103735_1 457415.HMPREF1006_02378 0.000396 50.1 COG0449@1|root,COG0449@2|Bacteria,3T9QF@508458|Synergistetes 508458|Synergistetes M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS - 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - - GATase_6,SIS k59_370556_1 679190.HMPREF0650_0103 6.88e-21 92.0 2AFQQ@1|root,315SK@2|Bacteria,4NJD4@976|Bacteroidetes,2FURH@200643|Bacteroidia 976|Bacteroidetes L NUMOD4 motif - - - - - - - - - - - - HNH_3,NUMOD4 k59_473596_2 291603.REP7_FBNY1 7.94e-21 96.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_1703_1 1125863.JAFN01000001_gene3542 4.8e-23 94.0 COG2852@1|root,COG2852@2|Bacteria,1N2UX@1224|Proteobacteria 1224|Proteobacteria S Protein conserved in bacteria - - - - - - - - - - - - - k59_22042_2 1298920.KI911353_gene2079 0.000416 50.1 COG4974@1|root,COG4974@2|Bacteria,1UMMQ@1239|Firmicutes,25GMC@186801|Clostridia,223S0@1506553|Lachnoclostridium 186801|Clostridia L Phage integrase SAM-like domain - - - - - - - - - - - - Phage_int_SAM_3,Phage_integrase k59_555337_1 145579.CAPSD_BPPHM 2.62e-23 104.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_186138_2 556269.ACDQ01000003_gene1354 3.78e-35 127.0 2C095@1|root,32VKM@2|Bacteria,1N0Y9@1224|Proteobacteria,2VUZF@28216|Betaproteobacteria 28216|Betaproteobacteria S Domain of unknown function (DUF1833) - - - - - - - - - - - - DUF1833 k59_186138_3 556269.ACDQ01000003_gene1355 2.15e-38 133.0 COG0791@1|root,COG0791@2|Bacteria,1NA3R@1224|Proteobacteria,2VXXX@28216|Betaproteobacteria 28216|Betaproteobacteria M to Bacteriophage D3 Orf25 SWALL Q9MC96 (EMBL AF165214) (135 aa) fasta scores E() 0.00047, 30.46 id in 128 aa - - - - - - - - - - - - NLPC_P60 k59_186138_4 272942.RCAP_rcc02907 1.38e-29 125.0 COG4733@1|root,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria,2TV2W@28211|Alphaproteobacteria,1FD1T@1060|Rhodobacter 28211|Alphaproteobacteria S COG4733 Phage-related protein, tail component - - - - - - - - - - - - Lambda_tail_I,Phage-tail_3 k59_452893_1 1380600.AUYN01000001_gene2726 1.58e-06 57.8 COG1361@1|root,COG2356@1|root,COG4932@1|root,COG5184@1|root,COG1361@2|Bacteria,COG2356@2|Bacteria,COG4932@2|Bacteria,COG5184@2|Bacteria,4NMB8@976|Bacteroidetes,1I0EW@117743|Flavobacteriia 976|Bacteroidetes M Domain of unknown function DUF11 - - - - - - - - - - - - CHU_C,DUF11,He_PIG k59_22053_1 1907.SGLAU_22065 9.09e-13 73.2 COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria 201174|Actinobacteria O Peptidase s1 and s6 chymotrypsin hap - - - ko:K08372 ko02020,map02020 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ_2,Trypsin_2 k59_452902_1 1618236.A0A0C5I2F3_9CIRC 1.99e-50 177.0 4QGVY@10239|Viruses,4QUKN@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_145129_1 1169143.KB911052_gene5725 3.06e-09 64.3 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2VJIV@28216|Betaproteobacteria,1K1JU@119060|Burkholderiaceae 28216|Betaproteobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdA GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN k59_596061_1 10224.XP_002739627.1 1.94e-24 107.0 COG1678@1|root,KOG1567@2759|Eukaryota,38B80@33154|Opisthokonta,3B9U0@33208|Metazoa,3CT3A@33213|Bilateria 33208|Metazoa F ribonucleoside-diphosphate reductase activity - - 1.17.4.1 ko:K10808 ko00230,ko00240,ko00480,ko00983,ko01100,ko04115,map00230,map00240,map00480,map00983,map01100,map04115 M00053 R02017,R02019,R02024,R08363,R08364,R11893 RC00613,RC01003 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_sm k59_186165_2 1574422.A0A0A1ENW9_9CIRC 2.27e-20 92.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_42479_1 232237.Q7Y5K0_9CAUD 1.68e-38 139.0 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales,4QKM7@10699|Siphoviridae 10699|Siphoviridae S HNH endonuclease - - - - - - - - - - - - - k59_42479_2 522306.CAP2UW1_0591 2.07e-18 80.5 COG3772@1|root,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,2VTZX@28216|Betaproteobacteria 28216|Betaproteobacteria G lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_514975_1 886293.Sinac_4186 9.08e-48 169.0 COG1783@1|root,COG1783@2|Bacteria 2|Bacteria S DNA packaging - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_6 k59_514976_2 323097.Nham_0299 3.57e-15 76.3 2AI98@1|root,318PV@2|Bacteria,1NMYH@1224|Proteobacteria 1224|Proteobacteria L HNH endonuclease - - - - - - - - - - - - HNH_3 k59_435745_4 172088.AUGA01000017_gene2295 2.33e-37 140.0 COG5323@1|root,COG5323@2|Bacteria,1MW8S@1224|Proteobacteria,2TREI@28211|Alphaproteobacteria,3JVEX@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_557689_1 1043205.AFYF01000028_gene267 2.29e-19 99.4 COG3087@1|root,COG3291@1|root,COG3087@2|Bacteria,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria,4FHZF@85021|Intrasporangiaceae 201174|Actinobacteria P PKD domain - - - - - - - - - - - - CHB_HEX_C_1,Laminin_G_3,PKD k59_229309_1 1172185.KB911514_gene4351 1.77e-21 105.0 COG1061@1|root,COG1061@2|Bacteria,2GIU5@201174|Actinobacteria,4FV1N@85025|Nocardiaceae 201174|Actinobacteria L Type III restriction enzyme, res subunit sdrA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - ResIII k59_147870_1 1234888.K0A2J2_9VIRU 2.95e-45 166.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_641227_1 935848.JAEN01000011_gene1848 2.11e-20 90.9 COG3409@1|root,COG3409@2|Bacteria,1RAYU@1224|Proteobacteria,2U6D1@28211|Alphaproteobacteria,2PXU7@265|Paracoccus 28211|Alphaproteobacteria M N-acetylmuramidase - - - - - - - - - - - - Muraidase,PG_binding_1 k59_393625_2 195253.Syn6312_0710 3.27e-15 85.1 COG1215@1|root,COG1215@2|Bacteria,1G12A@1117|Cyanobacteria,1H432@1129|Synechococcus 1117|Cyanobacteria M COG0463 Glycosyltransferases involved in cell wall biogenesis - - - - - - - - - - - - Glycos_transf_2 k59_393625_4 78245.Xaut_3722 1.53e-06 52.4 2FEUE@1|root,346TC@2|Bacteria,1MZPB@1224|Proteobacteria,2UC4Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_229314_1 49964.Q94MS4_9CAUD 1.94e-32 129.0 4QCUF@10239|Viruses,4QV7U@35237|dsDNA viruses no RNA stage,4QQ89@28883|Caudovirales,4QNCY@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_311558_1 1692244.A0A0K1RLR5_9CIRC 4.39e-49 166.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_373600_1 1218076.BAYB01000015_gene3200 7.15e-60 200.0 COG0305@1|root,COG0305@2|Bacteria,1PP51@1224|Proteobacteria,2VQ9Z@28216|Betaproteobacteria 28216|Betaproteobacteria L DnaB-like helicase C terminal domain - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - AAA_25,DnaB_C k59_148242_2 998674.ATTE01000001_gene1819 1.57e-29 111.0 COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,1RP86@1236|Gammaproteobacteria,460D0@72273|Thiotrichales 72273|Thiotrichales E Belongs to the UPF0758 family - - - ko:K03630 - - - - ko00000 - - - RadC k59_436422_2 1210884.HG799466_gene12740 1.28e-29 117.0 2C9JF@1|root,32RPD@2|Bacteria 2|Bacteria S Erf family - - - - - - - - - - - - ERF k59_620267_1 1618259.A0A0C5I2B5_9CIRC 1.53e-20 93.2 4QE84@10239|Viruses,4QUKR@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_66067_2 1692249.A0A0K1RL40_9CIRC 5.53e-50 173.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_394002_1 759914.BP951000_0891 1.47e-21 103.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2J5JP@203691|Spirochaetes 203691|Spirochaetes G Belongs to the PEP-utilizing enzyme family ppdK - 2.7.9.1 ko:K01006 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 M00169,M00171,M00172,M00173 R00206 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N k59_518491_1 644283.Micau_0333 2.5e-28 117.0 COG3559@1|root,COG3559@2|Bacteria,2GMSI@201174|Actinobacteria,4D9NV@85008|Micromonosporales 201174|Actinobacteria M exporter of polyketide - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - - k59_482961_1 1408473.JHXO01000001_gene2383 5.22e-34 132.0 COG0297@1|root,COG0297@2|Bacteria,4PKP8@976|Bacteroidetes,2G0CZ@200643|Bacteroidia 976|Bacteroidetes G Starch synthase catalytic domain - - - - - - - - - - - - Glyco_transf_4,Glyco_transf_5,Glycos_transf_1 k59_108672_2 1121946.AUAX01000012_gene6529 9.15e-06 57.4 COG5434@1|root,COG5434@2|Bacteria 2|Bacteria M polygalacturonase activity - - - - - - - - - - - - Beta_helix,Pectate_lyase_3 k59_131915_1 158189.SpiBuddy_2346 1.77e-26 109.0 COG0629@1|root,COG0629@2|Bacteria 2|Bacteria L single-stranded DNA binding - - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - ERF,SSB k59_624200_3 985255.APHJ01000018_gene3097 4.22e-27 110.0 COG5545@1|root,COG5545@2|Bacteria,4PMA3@976|Bacteroidetes,1IJP7@117743|Flavobacteriia 976|Bacteroidetes L VirE N-terminal domain - - - - - - - - - - - - DUF3987,PriCT_2,VirE,VirE_N k59_151585_2 1007105.PT7_P059 2e-50 174.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2VNHP@28216|Betaproteobacteria,3T3DM@506|Alcaligenaceae 28216|Betaproteobacteria S COG4626 Phage terminase-like protein, large subunit - - - - - - - - - - - - Terminase_1 k59_355549_2 1094558.ME5_00023 1.52e-22 90.9 2DR9Y@1|root,33AUY@2|Bacteria 2|Bacteria L HNH endonuclease domain protein - - - - - - - - - - - - HNH_3,NUMOD4 k59_192969_1 1033743.CAES01000078_gene3700 2.11e-12 80.5 COG3170@1|root,COG3170@2|Bacteria,1UMRZ@1239|Firmicutes 1239|Firmicutes NU Tfp pilus assembly protein FimV - - - - - - - - - - - - - k59_441443_2 443254.Marpi_0683 1.09e-07 63.2 COG0328@1|root,COG0507@1|root,COG0328@2|Bacteria,COG0507@2|Bacteria,2GDAC@200918|Thermotogae 200918|Thermotogae L Ribonuclease H - - - ko:K06993 - - - - ko00000 - - - AAA_30,Cauli_VI,RNase_H,UvrD_C_2 k59_441459_2 1183438.GKIL_2298 8.32e-32 124.0 COG0438@1|root,COG0438@2|Bacteria,1FZZP@1117|Cyanobacteria 1117|Cyanobacteria M PFAM Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k59_504562_1 1433126.BN938_1883 2.1e-65 209.0 COG0863@1|root,COG0863@2|Bacteria,4NUV9@976|Bacteroidetes 976|Bacteroidetes H DNA methylase - - - - - - - - - - - - N6_N4_Mtase k59_549877_1 691965.D4P7E6_9CAUD 7.57e-91 302.0 4QAK6@10239|Viruses,4R01K@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_401987_1 1538804.A0A088F6N3_9CAUD 1.1e-14 72.0 4QFW7@10239|Viruses,4QU0S@28883|Caudovirales,4QM9S@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_299973_5 668618.C8CGZ6_9CAUD 3.14e-32 118.0 4QD6Y@10239|Viruses,4QWG5@35237|dsDNA viruses no RNA stage,4QPFN@28883|Caudovirales 28883|Caudovirales S DNA N-6-adenine-methyltransferase (Dam) - - - - - - - - - - - - - k59_401989_2 545695.TREAZ_2066 3.09e-05 47.4 COG1396@1|root,COG1396@2|Bacteria,2J70F@203691|Spirochaetes 203691|Spirochaetes K Cupin 2, conserved barrel - - - - - - - - - - - - Cupin_2,HTH_3 k59_98460_2 1096930.L284_10055 1.37e-23 101.0 COG0343@1|root,COG0343@2|Bacteria,1NRFY@1224|Proteobacteria,2UPEW@28211|Alphaproteobacteria,2KAIE@204457|Sphingomonadales 204457|Sphingomonadales J queuine tRNA-ribosyltransferase activity - - - - - - - - - - - - - k59_13561_2 1332071.L581_2452 1.68e-45 152.0 COG3772@1|root,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,1S99W@1236|Gammaproteobacteria,405GZ@613|Serratia 1236|Gammaproteobacteria G Phage lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_319289_1 1121333.JMLH01000034_gene2863 0.000798 51.2 COG1196@1|root,COG1409@1|root,COG1524@1|root,COG5492@1|root,COG1196@2|Bacteria,COG1409@2|Bacteria,COG1524@2|Bacteria,COG5492@2|Bacteria,1VBVT@1239|Firmicutes,3VU1E@526524|Erysipelotrichia 526524|Erysipelotrichia DN Concanavalin A-like lectin/glucanases superfamily - - - - - - - - - - - - FIVAR,Laminin_G_3 k59_489155_1 1692249.A0A0K1RLN8_9CIRC 1.28e-20 92.0 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_586837_2 575540.Isop_2441 1.51e-41 142.0 2CEI6@1|root,2ZED5@2|Bacteria,2J3S1@203682|Planctomycetes 203682|Planctomycetes S Protein of unknown function (DUF669) - - - - - - - - - - - - DUF669 k59_586837_6 553217.ENHAE0001_2189 4.07e-54 180.0 COG1100@1|root,COG1100@2|Bacteria 2|Bacteria S GTP binding - - - - - - - - - - - - MMR_HSR1,Zeta_toxin k59_51279_1 1788447.A0A190WHJ9_9CIRC 8.17e-52 179.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_278838_1 209285.XP_006690972.1 6.33e-09 60.1 COG3772@1|root,2S6UW@2759|Eukaryota,3A2UF@33154|Opisthokonta,3P2E0@4751|Fungi,3QU3D@4890|Ascomycota,218H2@147550|Sordariomycetes,3UANI@5139|Sordariales,3H9ZA@35718|Chaetomiaceae 4751|Fungi G Phage lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme,SH3_3 k59_591120_1 1235755.ANAM01000008_gene1348 3.5e-08 55.1 COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,4HA9K@91061|Bacilli,4GX35@90964|Staphylococcaceae 91061|Bacilli J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dus - - - - - - - - - - - Dus k59_324162_1 745411.B3C1_16566 1.71e-61 198.0 COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,1RMG9@1236|Gammaproteobacteria,1J5W1@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) queC - 6.3.4.20 ko:K06920 ko00790,ko01100,map00790,map01100 - R09978 RC00959 ko00000,ko00001,ko01000,ko03016 - - - QueC k59_324162_2 1282876.BAOK01000001_gene2180 6.36e-58 189.0 COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,2TU1S@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds queE - 4.3.99.3 ko:K10026 ko00790,ko01100,map00790,map01100 - R10002 RC02989 ko00000,ko00001,ko01000,ko03016 - - - Fer4_14,Radical_SAM k59_324162_3 471874.PROSTU_03779 5.66e-24 95.9 COG0720@1|root,COG0720@2|Bacteria,1RI4P@1224|Proteobacteria,1S3T6@1236|Gammaproteobacteria,3Z96P@586|Providencia 1236|Gammaproteobacteria H synthase queD GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0070497,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 - - iECIAI39_1322.ECIAI39_2947,iUTI89_1310.UTI89_C3129,ic_1306.c3324 PTPS k59_37327_1 1618238.A0A0C5IB41_9CIRC 8.78e-32 128.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_264787_2 1049564.TevJSym_au00620 2.72e-05 47.8 COG0568@1|root,COG0568@2|Bacteria,1MUDI@1224|Proteobacteria,1RN8V@1236|Gammaproteobacteria,1J4VY@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K COG0568 DNA-directed RNA polymerase, sigma subunit rpoS GO:0000988,GO:0000990,GO:0001000,GO:0001121,GO:0001123,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - ko:K03087 ko02026,ko05111,map02026,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 k59_264787_3 673832.D2IYU1_9CAUD 1.25e-15 73.6 4QAQV@10239|Viruses,4QUPK@35237|dsDNA viruses no RNA stage,4QPCB@28883|Caudovirales,4QKM5@10699|Siphoviridae 10699|Siphoviridae S sequence-specific DNA binding - - - - - - - - - - - - - k59_264791_1 1336245.JAGO01000012_gene1702 2.76e-15 84.3 COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,1RMS8@1236|Gammaproteobacteria,1XIND@135619|Oceanospirillales 135619|Oceanospirillales M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) slt - - ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 - SLT,SLT_L k59_18428_2 926692.AZYG01000075_gene2443 5.77e-37 147.0 COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,24CD5@186801|Clostridia,3WB04@53433|Halanaerobiales 186801|Clostridia O Peptidase S8 and S53 subtilisin kexin sedolisin - - - ko:K14645,ko:K20486 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - Big_2,Peptidase_S8 k59_18428_3 5911.EAS01484 0.000328 52.8 KOG4721@1|root,KOG4721@2759|Eukaryota 2759|Eukaryota T MAP kinase kinase kinase activity MAP3K13 GO:0000003,GO:0000165,GO:0000186,GO:0000187,GO:0000902,GO:0000904,GO:0001558,GO:0001932,GO:0001934,GO:0003008,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004709,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006325,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0007030,GO:0007154,GO:0007165,GO:0007254,GO:0007275,GO:0007276,GO:0007283,GO:0007399,GO:0007409,GO:0007610,GO:0007611,GO:0007613,GO:0007616,GO:0008022,GO:0008150,GO:0008152,GO:0008361,GO:0009611,GO:0009653,GO:0009889,GO:0009893,GO:0009894,GO:0009966,GO:0009967,GO:0009987,GO:0010256,GO:0010468,GO:0010556,GO:0010562,GO:0010604,GO:0010608,GO:0010646,GO:0010647,GO:0010720,GO:0010769,GO:0010770,GO:0010941,GO:0010975,GO:0010976,GO:0016020,GO:0016043,GO:0016049,GO:0016301,GO:0016310,GO:0016569,GO:0016570,GO:0016572,GO:0016740,GO:0016772,GO:0016773,GO:0018105,GO:0018107,GO:0018193,GO:0018209,GO:0018210,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0019899,GO:0019900,GO:0019901,GO:0019953,GO:0022008,GO:0022414,GO:0022603,GO:0022604,GO:0023014,GO:0023051,GO:0023052,GO:0023056,GO:0030030,GO:0030154,GO:0030182,GO:0030307,GO:0030424,GO:0030426,GO:0030427,GO:0030516,GO:0031098,GO:0031099,GO:0031102,GO:0031103,GO:0031175,GO:0031323,GO:0031325,GO:0031326,GO:0031329,GO:0031344,GO:0031346,GO:0031399,GO:0031401,GO:0031625,GO:0032101,GO:0032103,GO:0032147,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032504,GO:0032535,GO:0032879,GO:0032989,GO:0032990,GO:0033267,GO:0033554,GO:0033674,GO:0035556,GO:0036211,GO:0036477,GO:0040007,GO:0040008,GO:0040012,GO:0042325,GO:0042327,GO:0042802,GO:0042803,GO:0042981,GO:0042995,GO:0043005,GO:0043025,GO:0043066,GO:0043067,GO:0043069,GO:0043085,GO:0043170,GO:0043405,GO:0043406,GO:0043408,GO:0043410,GO:0043412,GO:0043487,GO:0043488,GO:0043523,GO:0043524,GO:0043549,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044297,GO:0044389,GO:0044424,GO:0044444,GO:0044463,GO:0044464,GO:0044703,GO:0045202,GO:0045595,GO:0045597,GO:0045664,GO:0045666,GO:0045773,GO:0045859,GO:0045860,GO:0045927,GO:0045937,GO:0046777,GO:0046983,GO:0048232,GO:0048468,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048588,GO:0048589,GO:0048609,GO:0048638,GO:0048639,GO:0048666,GO:0048667,GO:0048668,GO:0048674,GO:0048675,GO:0048677,GO:0048678,GO:0048679,GO:0048680,GO:0048682,GO:0048686,GO:0048687,GO:0048689,GO:0048690,GO:0048691,GO:0048699,GO:0048731,GO:0048812,GO:0048841,GO:0048856,GO:0048858,GO:0048869,GO:0050767,GO:0050769,GO:0050770,GO:0050772,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050803,GO:0050807,GO:0050877,GO:0050890,GO:0050896,GO:0050920,GO:0051090,GO:0051091,GO:0051092,GO:0051094,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051174,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051252,GO:0051270,GO:0051276,GO:0051338,GO:0051347,GO:0051403,GO:0051704,GO:0051716,GO:0051960,GO:0051962,GO:0060255,GO:0060284,GO:0060548,GO:0060560,GO:0061013,GO:0061387,GO:0061564,GO:0065007,GO:0065008,GO:0065009,GO:0070570,GO:0070572,GO:0071704,GO:0071840,GO:0071900,GO:0071902,GO:0071944,GO:0072375,GO:0080090,GO:0080134,GO:0080135,GO:0090066,GO:0097458,GO:0099174,GO:0120025,GO:0120035,GO:0120036,GO:0120038,GO:0120039,GO:0140096,GO:0150034,GO:1901214,GO:1901215,GO:1901564,GO:1902531,GO:1902533,GO:1902667,GO:1903034,GO:1903036,GO:1903311,GO:1903506,GO:1903616,GO:1905868,GO:1990138,GO:2000026,GO:2000112,GO:2000331,GO:2000671,GO:2000672,GO:2001141 2.7.11.25 ko:K04422,ko:K04423 ko04010,map04010 M00688,M00689 - - ko00000,ko00001,ko00002,ko01000,ko01001 - - - Pkinase,Pkinase_Tyr k59_116300_1 1235798.C817_04103 5.02e-57 201.0 COG4626@1|root,COG4626@2|Bacteria,1TPU1@1239|Firmicutes,248RI@186801|Clostridia 186801|Clostridia L Phage terminase-like protein large subunit - - - - - - - - - - - - LAGLIDADG_3,Terminase_1 k59_141860_1 323097.Nham_0587 1.88e-08 63.9 COG1520@1|root,COG1520@2|Bacteria 2|Bacteria S amino acid activation for nonribosomal peptide biosynthetic process - - - - - - - - - - - - FG-GAP_2,PQQ_2 k59_324877_3 742740.HMPREF9474_02272 8.82e-33 126.0 COG4626@1|root,COG4626@2|Bacteria,1TT9I@1239|Firmicutes,24AFK@186801|Clostridia,222GA@1506553|Lachnoclostridium 186801|Clostridia S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_219603_1 1051675.G0YQH7_9CAUD 1.64e-09 64.7 4QGGR@10239|Viruses,4QZHR@35237|dsDNA viruses no RNA stage,4QUGZ@28883|Caudovirales,4QNY3@10744|Podoviridae 10744|Podoviridae S viral capsid - - - - - - - - - - - - - k59_324889_1 529818.AMSG_12187T0 2.14e-08 57.8 COG5082@1|root,KOG4400@2759|Eukaryota 2759|Eukaryota OU zinc ion binding ZCCHC7 GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005829,GO:0031974,GO:0031981,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0070013 - ko:K12597 ko03018,map03018 M00393 - - ko00000,ko00001,ko00002,ko03016,ko03019 - - - zf-CCHC k59_305014_1 1094980.Mpsy_0622 2.79e-26 104.0 COG1961@1|root,arCOG03162@2157|Archaea,2Y10R@28890|Euryarchaeota 28890|Euryarchaeota L Resolvase helix-turn-helix domain protein - - - - - - - - - - - - HTH_7,Recombinase,Resolvase k59_142467_1 742925.D4N3R4_9CIRC 3.87e-15 78.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_142467_3 645099.MREP_BBTVA 1.97e-14 76.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_37976_1 981369.JQMJ01000004_gene3739 1.5e-103 316.0 COG0766@1|root,COG0766@2|Bacteria,2GJPW@201174|Actinobacteria,2NFUI@228398|Streptacidiphilus 201174|Actinobacteria M EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) murA - 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - - EPSP_synthase,HTH_3 k59_160363_2 1173263.Syn7502_01470 2.22e-23 95.1 COG4990@1|root,COG4990@2|Bacteria,1GHGJ@1117|Cyanobacteria 1117|Cyanobacteria S Peptidase_C39 like family - - - - - - - - - - - - Peptidase_C39_2 k59_388113_1 929712.KI912613_gene398 3.17e-05 50.8 2EGQU@1|root,33AGZ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Collagen k59_513574_3 350688.Clos_1826 1.34e-06 57.4 28KEB@1|root,2ZA0K@2|Bacteria,1V14E@1239|Firmicutes,25K6P@186801|Clostridia,36PDM@31979|Clostridiaceae 186801|Clostridia S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - - k59_164647_1 1341151.ASZU01000004_gene266 4.72e-13 73.9 2EAVR@1|root,334X3@2|Bacteria,1VHXF@1239|Firmicutes,4HSF1@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k59_554462_1 697281.Mahau_2402 1.68e-08 58.5 COG0739@1|root,COG5492@1|root,COG0739@2|Bacteria,COG5492@2|Bacteria,1UMBK@1239|Firmicutes,25GPY@186801|Clostridia 186801|Clostridia N domain, Protein - - - - - - - - - - - - - k59_82855_1 1300150.EMQU_2511 4.95e-52 181.0 COG0270@1|root,COG0270@2|Bacteria,1TS3G@1239|Firmicutes,4IPYS@91061|Bacilli,4B6QJ@81852|Enterococcaceae 91061|Bacilli H C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_513576_2 1538804.A0A088F6T3_9CAUD 2.81e-33 132.0 4QAKM@10239|Viruses,4QPEF@28883|Caudovirales,4QKNE@10699|Siphoviridae 10699|Siphoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_595393_1 498761.HM1_0049 9.81e-59 196.0 COG4383@1|root,COG4383@2|Bacteria,1TS7T@1239|Firmicutes,24CCB@186801|Clostridia 186801|Clostridia S Mu-like prophage protein gp29 - - - - - - - - - - - - - k59_390360_1 1298867.AUES01000066_gene4687 3.61e-15 82.0 COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,1MVH7@1224|Proteobacteria,2TRNA@28211|Alphaproteobacteria,3JW7V@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria KL DNA methylase - - - - - - - - - - - - N6_N4_Mtase,ParBc k59_185387_1 654929.REP_PCV1C 4.31e-34 133.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_185387_2 1618236.A0A0C5I2F3_9CIRC 9.54e-52 182.0 4QGVY@10239|Viruses,4QUKN@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_267505_1 1468411.X2KPA0_9CAUD 2.52e-42 155.0 4QGHR@10239|Viruses,4QWID@35237|dsDNA viruses no RNA stage,4QTRG@28883|Caudovirales,4QKSH@10699|Siphoviridae 10699|Siphoviridae S Queuosine biosynthesis protein QueC - - - - - - - - - - - - - k59_431204_1 1313292.BCO_0032400 4.68e-22 101.0 COG1643@1|root,COG1643@2|Bacteria,2J58M@203691|Spirochaetes 203691|Spirochaetes L Helicase hrpA - - - - - - - - - - - DEAD,HA2,Helicase_C,OB_NTP_bind k59_533938_1 1463881.KL591003_gene5860 1.2e-06 63.2 COG1293@1|root,COG5283@1|root,COG1293@2|Bacteria,COG5283@2|Bacteria,2I92I@201174|Actinobacteria 201174|Actinobacteria M Phage tail tape measure protein, TP901 family - - - - - - - - - - - - PhageMin_Tail k59_390805_1 691965.D4P7L7_9CAUD 2.14e-80 266.0 4QB9J@10239|Viruses,4QXFE@35237|dsDNA viruses no RNA stage,4QS1Z@28883|Caudovirales,4QN8F@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_616485_1 862971.SANR_1063 1.46e-05 50.8 COG0270@1|root,COG0270@2|Bacteria,1TSNX@1239|Firmicutes,4HDW0@91061|Bacilli 91061|Bacilli L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family dcm - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase,HTH_26,HTH_3 k59_123903_2 269482.Bcep1808_1155 4.64e-36 132.0 2DM17@1|root,319VU@2|Bacteria,1R6RI@1224|Proteobacteria,2WG8E@28216|Betaproteobacteria,1KIBI@119060|Burkholderiaceae 28216|Betaproteobacteria L PFAM GIY-YIG catalytic domain - - - - - - - - - - - - - k59_473011_3 1206101.AZXC01000001_gene4761 1.75e-12 66.6 COG1403@1|root,COG1403@2|Bacteria,2GYWG@201174|Actinobacteria 201174|Actinobacteria L HNH endonuclease - - - - - - - - - - - - HNH,HNH_3 k59_86323_20 1127692.HMPREF9075_01018 4.45e-09 63.2 COG4974@1|root,COG4974@2|Bacteria,4NGQW@976|Bacteroidetes,1HWMN@117743|Flavobacteriia,1EQ7K@1016|Capnocytophaga 976|Bacteroidetes L Belongs to the 'phage' integrase family xerC - - ko:K03733 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase k59_640501_2 1185876.BN8_06414 4.56e-11 69.7 COG3291@1|root,COG3291@2|Bacteria,4P6HC@976|Bacteroidetes,47YA8@768503|Cytophagia 2|Bacteria S Concanavalin A-like lectin/glucanases superfamily - - 3.1.4.46,3.2.1.8 ko:K01126,ko:K01181 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - CHU_C,Laminin_G_3,NLPC_P60,PKD,fn3 k59_598635_8 478749.BRYFOR_08548 1.02e-19 88.6 2AUTU@1|root,31KGW@2|Bacteria,1V7KU@1239|Firmicutes,24K4D@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_229198_1 145579.CAPSD_BPPHM 8.66e-23 103.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_414162_1 1692256.A0A0K1RL85_9CIRC 3.47e-27 107.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_332976_1 1458357.BG58_33125 2.13e-44 166.0 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,2VP7E@28216|Betaproteobacteria,1KFK1@119060|Burkholderiaceae 28216|Betaproteobacteria S Phage portal protein - - - - - - - - - - - - Phage_portal k59_538360_2 1051675.G0YQF5_9CAUD 3.43e-37 142.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_373030_2 1165094.RINTHH_3920 1.12e-66 218.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_373030_5 1385658.U5KPZ6_9VIRU 3.73e-62 211.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_270577_5 209285.XP_006690972.1 1.58e-11 66.2 COG3772@1|root,2S6UW@2759|Eukaryota,3A2UF@33154|Opisthokonta,3P2E0@4751|Fungi,3QU3D@4890|Ascomycota,218H2@147550|Sordariomycetes,3UANI@5139|Sordariales,3H9ZA@35718|Chaetomiaceae 4751|Fungi G Phage lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme,SH3_3 k59_147748_1 1379722.S5SY31_9CIRC 2.37e-49 164.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_393548_5 469371.Tbis_2241 3.86e-14 70.1 2CC1Y@1|root,32S23@2|Bacteria,2IQS5@201174|Actinobacteria,4E5XQ@85010|Pseudonocardiales 201174|Actinobacteria K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA whiB3 - - ko:K18955 - - - - ko00000,ko03000 - - - Whib k59_352108_1 1165094.RINTHH_3920 7.82e-19 86.7 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_482299_1 1353529.M899_1105 4.1e-06 54.3 COG0729@1|root,COG2911@1|root,COG0729@2|Bacteria,COG2911@2|Bacteria,1QY25@1224|Proteobacteria,43C9F@68525|delta/epsilon subdivisions,2MUT5@213481|Bdellovibrionales,2X7JW@28221|Deltaproteobacteria 213481|Bdellovibrionales M cell wall surface anchor family protein - - - - - - - - - - - - Peptidase_S74 k59_543034_1 349966.DJ58_4330 0.000325 47.4 2DZIT@1|root,32VBT@2|Bacteria,1RK3Y@1224|Proteobacteria,1S8C1@1236|Gammaproteobacteria,41H3T@629|Yersinia 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_192455_1 1054968.G0X507_9CAUD 1.62e-14 73.6 4QAUS@10239|Viruses,4QURX@35237|dsDNA viruses no RNA stage,4QQ2S@28883|Caudovirales,4QNNP@10744|Podoviridae 10744|Podoviridae S flavin adenine dinucleotide binding - - - - - - - - - - - - - k59_192455_7 1027371.GOALK_093_00420 2e-22 94.4 2E5GW@1|root,3308F@2|Bacteria,2GX64@201174|Actinobacteria 201174|Actinobacteria S Protein of unknwon function (DUF3310) - - - - - - - - - - - - DUF3310 k59_192455_8 31535.Q9MC50_BPD3 3.28e-36 132.0 4QBHW@10239|Viruses,4QW8N@35237|dsDNA viruses no RNA stage,4QTT7@28883|Caudovirales,4QKR7@10699|Siphoviridae 10699|Siphoviridae S sequence-specific DNA binding transcription factor activity - - - - - - - - - - - - - k59_192455_9 1410676.JNKL01000021_gene1104 1.9e-29 114.0 COG2131@1|root,COG2131@2|Bacteria,1RD1P@1224|Proteobacteria,1SFR6@1236|Gammaproteobacteria 1236|Gammaproteobacteria F PFAM CMP dCMP deaminase zinc-binding - - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 k59_192455_11 525146.Ddes_2235 1.28e-41 168.0 COG3378@1|root,COG3378@2|Bacteria,1PDTD@1224|Proteobacteria,42TSY@68525|delta/epsilon subdivisions,2WV92@28221|Deltaproteobacteria,2M9V8@213115|Desulfovibrionales 28221|Deltaproteobacteria S Phage plasmid primase P4 family - - - - - - - - - - - - - k59_192455_13 1525715.IX54_11130 1.33e-06 51.2 2DP75@1|root,330U8@2|Bacteria,1N8XA@1224|Proteobacteria,2UIHW@28211|Alphaproteobacteria 28211|Alphaproteobacteria L PFAM Pathogenesis-related transcriptional factor and ERF protein - - - - - - - - - - - - AP2,HNH_3 k59_69456_1 1121090.KB894685_gene3942 1.45e-06 57.8 COG0741@1|root,COG0741@2|Bacteria,1V6DD@1239|Firmicutes,4HIWA@91061|Bacilli,1ZH33@1386|Bacillus 91061|Bacilli M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) yjbJ - - - - - - - - - - - SLT k59_646305_1 743299.Acife_1194 3.94e-43 160.0 COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,1RMMN@1236|Gammaproteobacteria,2NC0G@225057|Acidithiobacillales 225057|Acidithiobacillales M TIGRFAM Undecaprenyl-phosphate galactose phosphotransferase, WbaP - - 2.7.8.6 ko:K00996 - - - - ko00000,ko01000,ko01005 - - - Bac_transf,CoA_binding_3 k59_28024_1 2340.JV46_13390 5.9e-18 87.8 COG1996@1|root,COG1996@2|Bacteria 2|Bacteria K Psort location Cytoplasmic, score - - - - - - - - - - - - DUF4379 k59_295057_1 699218.HMPREF0889_0300 2.6e-06 50.4 COG4570@1|root,COG4570@2|Bacteria 2|Bacteria L crossover junction endodeoxyribonuclease activity rusA - - - - - - - - - - - RusA k59_69462_1 1234888.K0A2J2_9VIRU 8.69e-40 149.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_28372_4 417280.A1YZY2_9CAUD 1.2e-60 217.0 4QCZC@10239|Viruses,4QX3V@35237|dsDNA viruses no RNA stage,4QRH3@28883|Caudovirales,4QHVR@10662|Myoviridae 10662|Myoviridae S Bacterial DNA polymerase III alpha subunit - - - - - - - - - - - - - k59_582207_1 1417599.U6C865_9CAUD 7.85e-07 54.7 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales,4QNBQ@10744|Podoviridae 10744|Podoviridae S HNH endonuclease - - - - - - - - - - - - - k59_482841_2 1385658.U5KQQ9_9VIRU 6.47e-32 123.0 4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_561571_1 1487921.DP68_11250 3.85e-39 146.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,36DK9@31979|Clostridiaceae 186801|Clostridia L snf2 family - - - - - - - - - - - - SNF2_N k59_459972_3 375286.mma_2211 1.16e-42 148.0 COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,2W3M1@28216|Betaproteobacteria,475QA@75682|Oxalobacteraceae 28216|Betaproteobacteria L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_459972_5 5671.XP_001468508.1 3.24e-19 100.0 COG0749@1|root,KOG0950@2759|Eukaryota,3XSG4@5653|Kinetoplastida 5653|Kinetoplastida H Mitochondrial DNA polymerase I protein A POL1A - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - DNA_pol_A k59_418426_2 330396.A8ATF8_9CAUD 8.2e-12 64.3 4QAKE@10239|Viruses,4QUP7@35237|dsDNA viruses no RNA stage,4QPCE@28883|Caudovirales,4QKTX@10699|Siphoviridae 10699|Siphoviridae S HNH endonuclease - - - - - - - - - - - - - k59_274412_1 411462.DORLON_00791 7.07e-18 82.0 2CWXD@1|root,32T0J@2|Bacteria,1V83I@1239|Firmicutes,25DQF@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - AP2 k59_274412_2 685782.O99_00932 2.73e-11 63.9 COG3772@1|root,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,2U7RQ@28211|Alphaproteobacteria,48UN8@772|Bartonellaceae 28211|Alphaproteobacteria G Phage lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_91809_1 36875.HQ29_07085 4.44e-05 52.0 COG0270@1|root,COG0270@2|Bacteria,4NG9A@976|Bacteroidetes,2FNPZ@200643|Bacteroidia,22YTP@171551|Porphyromonadaceae 976|Bacteroidetes L C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_459988_1 716928.AJQT01000109_gene1208 9.82e-05 44.3 2DIIY@1|root,303ET@2|Bacteria,1RD2S@1224|Proteobacteria,2U8HK@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_50373_3 1423734.JCM14202_1053 2.44e-08 56.6 COG1476@1|root,COG2932@1|root,COG1476@2|Bacteria,COG2932@2|Bacteria,1VAT3@1239|Firmicutes,4HM0X@91061|Bacilli,3F8CM@33958|Lactobacillaceae 91061|Bacilli K Peptidase S24-like - - - - - - - - - - - - HTH_3,Peptidase_S24 k59_176807_1 1175654.A0A0S0NAE3_9CAUD 1.32e-09 63.9 4QB5I@10239|Viruses,4QWYV@35237|dsDNA viruses no RNA stage,4QTTK@28883|Caudovirales,4QM8X@10699|Siphoviridae 10699|Siphoviridae S ATP-dependent DNA helicase activity - - - - - - - - - - - - - k59_31647_3 935866.JAER01000006_gene3401 4.83e-45 167.0 COG4653@1|root,COG4653@2|Bacteria,2ICZP@201174|Actinobacteria 201174|Actinobacteria S Phage capsid family - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_400812_3 1122176.KB903543_gene601 7.69e-06 49.7 COG0305@1|root,COG1372@1|root,COG0305@2|Bacteria,COG1372@2|Bacteria,4NF8P@976|Bacteroidetes,1IPIQ@117747|Sphingobacteriia 976|Bacteroidetes L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_214108_4 1986029.Q9MBM3_9VIRU 2.02e-50 176.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_236128_1 2003327.CAPSD_BPCHP 6.31e-10 65.1 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_527888_1 132113.XP_003484918.1 8.58e-05 50.8 COG0417@1|root,KOG0969@2759|Eukaryota,38DSD@33154|Opisthokonta,3C0ZN@33208|Metazoa,3CT03@33213|Bilateria,41WFZ@6656|Arthropoda,3SJV7@50557|Insecta,46GCJ@7399|Hymenoptera 33208|Metazoa L DNA polymerase POLD1 GO:0000109,GO:0000228,GO:0000723,GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003684,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005657,GO:0005694,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006283,GO:0006284,GO:0006287,GO:0006289,GO:0006296,GO:0006297,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007049,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016043,GO:0016234,GO:0016235,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0018130,GO:0019438,GO:0019725,GO:0019899,GO:0019985,GO:0022402,GO:0030894,GO:0031974,GO:0031981,GO:0032200,GO:0032201,GO:0032991,GO:0032993,GO:0033260,GO:0033554,GO:0033683,GO:0034061,GO:0034641,GO:0034644,GO:0034645,GO:0034654,GO:0042575,GO:0042592,GO:0042769,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043596,GO:0043601,GO:0043625,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044454,GO:0044464,GO:0044786,GO:0045004,GO:0045005,GO:0046483,GO:0048878,GO:0050801,GO:0050896,GO:0051276,GO:0051606,GO:0051716,GO:0055081,GO:0055088,GO:0055089,GO:0060249,GO:0061695,GO:0065007,GO:0065008,GO:0070013,GO:0071214,GO:0071478,GO:0071482,GO:0071704,GO:0071840,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0104004,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990234,GO:1990391 2.7.7.7 ko:K02327 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03430,ko03440,ko05166,map00230,map00240,map01100,map03030,map03410,map03420,map03430,map03440,map05166 M00262 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol_B,DNA_pol_B_exo1,zf-C4pol k59_548259_1 929703.KE386491_gene1258 9.02e-43 174.0 COG3941@1|root,COG3941@2|Bacteria,4PP2D@976|Bacteroidetes,47YF4@768503|Cytophagia 976|Bacteroidetes S tape measure - - - - - - - - - - - - - k59_278089_1 1788454.A0A190WHE4_9CIRC 3.29e-39 141.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_565285_1 759938.F5BSB4_9CIRC 5.65e-09 57.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_111171_1 469660.A8HP51_9CAUD 2.99e-31 122.0 4QBFR@10239|Viruses,4QV1E@35237|dsDNA viruses no RNA stage,4QPRX@28883|Caudovirales,4QNJQ@10744|Podoviridae 10744|Podoviridae S ERF superfamily - - - - - - - - - - - - - k59_54185_1 1027292.HMPREF9372_2654 1.18e-07 59.3 COG3378@1|root,COG4983@1|root,COG3378@2|Bacteria,COG4983@2|Bacteria,1TQP9@1239|Firmicutes,4HBTB@91061|Bacilli,26FA9@186818|Planococcaceae 91061|Bacilli S D5 N terminal like - - - ko:K06919 - - - - ko00000 - - - D5_N,Pox_D5 k59_54833_1 1234888.K0A2J2_9VIRU 2.58e-58 199.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_218553_2 1430331.EP10_02375 4.81e-20 87.8 COG2887@1|root,COG2887@2|Bacteria,1UYIX@1239|Firmicutes,4HF6W@91061|Bacilli 91061|Bacilli L AAA domain - - - - - - - - - - - - AAA_24,PDDEXK_1 k59_115934_2 861530.ALOZ01000074_gene990 3.88e-15 78.6 2DR9Y@1|root,33AUY@2|Bacteria,1VEP1@1239|Firmicutes,4HIWW@91061|Bacilli,4GZZG@90964|Staphylococcaceae 91061|Bacilli L HNH endonuclease - - - - - - - - - - - - HNH_3,NUMOD4 k59_218608_1 145579.CAPSD_BPPHM 3.42e-50 178.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_406165_1 1120973.AQXL01000132_gene2202 2.21e-62 205.0 COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,4HA5K@91061|Bacilli,2785X@186823|Alicyclobacillaceae 91061|Bacilli E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT k59_183012_2 882.DVU_1504 5.42e-24 96.7 COG3747@1|root,COG3747@2|Bacteria,1RBBT@1224|Proteobacteria,42MD1@68525|delta/epsilon subdivisions,2WKZF@28221|Deltaproteobacteria,2MCYR@213115|Desulfovibrionales 28221|Deltaproteobacteria L Phage terminase, small subunit - - - - - - - - - - - - Terminase_4 k59_406179_1 985762.SAGN_03060 2.21e-12 67.4 COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,4HCDG@91061|Bacilli,4GYFW@90964|Staphylococcaceae 91061|Bacilli F ComE operon protein 2 comEB - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 k59_183014_2 1151061.CAJY01000041_gene672 1.09e-18 80.9 2E46I@1|root,332GH@2|Bacteria,2I85D@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_267936_1 1566993.A0A0A7HE43_9CAUD 9.17e-07 56.6 4QDKV@10239|Viruses,4QSYY@28883|Caudovirales,4QJAG@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_534434_2 748280.NH8B_2802 3.46e-41 149.0 28HEE@1|root,2Z7QU@2|Bacteria,1MXU6@1224|Proteobacteria,2VISI@28216|Betaproteobacteria,2KPKY@206351|Neisseriales 206351|Neisseriales S Domain of unknown function (DUF932) - - - - - - - - - - - - DUF932 k59_308520_1 1385658.U5KPZ6_9VIRU 3.93e-59 199.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_390898_1 545695.TREAZ_0592 5.49e-51 175.0 COG1196@1|root,COG1196@2|Bacteria 2|Bacteria D nuclear chromosome segregation - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - Dam,PhageMin_Tail k59_637112_1 417280.A1YZY2_9CAUD 7.06e-50 182.0 4QCZC@10239|Viruses,4QX3V@35237|dsDNA viruses no RNA stage,4QRH3@28883|Caudovirales,4QHVR@10662|Myoviridae 10662|Myoviridae S Bacterial DNA polymerase III alpha subunit - - - - - - - - - - - - - k59_452415_1 1234888.K0A2J2_9VIRU 7.16e-63 211.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_534440_1 1122164.JHWF01000053_gene1415 8.02e-30 114.0 2CBKC@1|root,32RTJ@2|Bacteria,1N5I0@1224|Proteobacteria,1SACI@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_288195_6 212042.APH_0571 2.77e-11 73.6 COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,2TRU2@28211|Alphaproteobacteria,47ETE@766|Rickettsiales 766|Rickettsiales L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 k59_370133_1 665950.HMPREF1025_01961 1.19e-119 355.0 COG0553@1|root,COG0553@2|Bacteria,1TS9W@1239|Firmicutes,24CGX@186801|Clostridia 186801|Clostridia KL Helicase conserved C-terminal domain - - - - - - - - - - - - - k59_370133_3 742740.HMPREF9474_02280 5.47e-33 117.0 2CGGB@1|root,32UNH@2|Bacteria,1VD9W@1239|Firmicutes,24MWC@186801|Clostridia,2235P@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_370133_4 691965.D4P7L6_9CAUD 8.55e-81 244.0 4QFKG@10239|Viruses,4QV77@35237|dsDNA viruses no RNA stage,4QR6Q@28883|Caudovirales,4QMGT@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_370133_5 691965.D4P7L7_9CAUD 6.39e-27 113.0 4QB9J@10239|Viruses,4QXFE@35237|dsDNA viruses no RNA stage,4QS1Z@28883|Caudovirales,4QN8F@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_431561_2 1234888.K0A2J2_9VIRU 1.53e-25 105.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_329583_1 548476.cauri_1937 0.000245 45.1 2EGYA@1|root,33AQE@2|Bacteria,2I84S@201174|Actinobacteria,22P16@1653|Corynebacteriaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_308547_2 1175654.A0A0S0N882_9CAUD 4.19e-20 86.7 4QE70@10239|Viruses,4QSZC@28883|Caudovirales,4QMIW@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_247624_2 5811.TGME49_027080 2.4e-10 68.6 28P6D@1|root,2QVT7@2759|Eukaryota,3YC0H@5794|Apicomplexa,3YIRE@5796|Coccidia,3YQX4@5809|Sarcocystidae 5794|Apicomplexa A Phosphorylated CTD interacting factor 1 WW domain - - - ko:K17584 - - - - ko00000,ko01009 - - - PCIF1_WW k59_1356_1 1618238.A0A0C5IB41_9CIRC 9.82e-39 147.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_41935_1 1406780.U5PWH9_9CAUD 7.36e-20 93.2 4QBY0@10239|Viruses,4QW35@35237|dsDNA viruses no RNA stage,4QQ4Q@28883|Caudovirales,4QNNN@10744|Podoviridae 10744|Podoviridae S UvrD-like helicase C-terminal domain - - - - - - - - - - - - - k59_107020_1 525257.HMPREF0204_11338 1.64e-60 196.0 COG0270@1|root,COG0270@2|Bacteria,4P3NG@976|Bacteroidetes,1I91K@117743|Flavobacteriia 976|Bacteroidetes L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_67819_1 204773.HEAR2273 2.33e-32 122.0 2CWXD@1|root,32T0J@2|Bacteria,1N3Z7@1224|Proteobacteria,2WBUY@28216|Betaproteobacteria,477U0@75682|Oxalobacteraceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_559702_1 395492.Rleg2_0410 1.42e-05 49.3 COG0451@1|root,COG0451@2|Bacteria,1QUEV@1224|Proteobacteria,2U8DY@28211|Alphaproteobacteria,4B9JJ@82115|Rhizobiaceae 28211|Alphaproteobacteria M Male sterility protein - - - - - - - - - - - - Epimerase,GDP_Man_Dehyd k59_375459_2 388051.AUFE01000035_gene4020 1.05e-88 280.0 COG4653@1|root,COG4653@2|Bacteria 2|Bacteria G Phage capsid family - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_395521_1 1548905.A0A0A1IV55_9CAUD 1.63e-59 199.0 4QAUT@10239|Viruses,4QQ7X@28883|Caudovirales,4QKVS@10699|Siphoviridae 10699|Siphoviridae S DNA ligase (ATP) activity - - - - - - - - - - - - - k59_6818_9 997352.HMPREF9419_1498 0.000488 43.1 COG0393@1|root,COG0393@2|Bacteria,4NQGB@976|Bacteroidetes,2FT9V@200643|Bacteroidia 976|Bacteroidetes S Belongs to the UPF0145 family - - - - - - - - - - - - YbjQ_1 k59_189918_10 1077972.ARGLB_083_00870 6.76e-27 107.0 arCOG05626@1|root,2Z9D9@2|Bacteria,2IIAB@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_5859_1 592015.HMPREF1705_00528 0.000195 50.4 2DS9D@1|root,33F48@2|Bacteria,3TBQW@508458|Synergistetes 508458|Synergistetes S Helix-turn-helix domain - - - - - - - - - - - - HTH_36 k59_599997_1 318464.IO99_00635 2.26e-10 71.2 COG5281@1|root,COG5281@2|Bacteria,1TPWF@1239|Firmicutes,24A8R@186801|Clostridia,36GW3@31979|Clostridiaceae 186801|Clostridia S tape measure - - - - - - - - - - - - - k59_312198_2 1094466.KQS_11905 4.65e-06 54.7 COG5272@1|root,COG5295@1|root,COG5272@2|Bacteria,COG5295@2|Bacteria,4NHCC@976|Bacteroidetes,1I3GX@117743|Flavobacteriia,2NZZ3@237|Flavobacterium 976|Bacteroidetes UW tail collar domain protein - - - - - - - - - - - - Collagen k59_539937_1 1202768.JROF01000022_gene3289 2.77e-07 54.3 arCOG10187@1|root,arCOG10187@2157|Archaea 2157|Archaea - - - - - - - - - - - - - - - k59_88236_1 1692244.A0A0K1RLR5_9CIRC 1.14e-91 278.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_312200_1 1123024.AUII01000012_gene4145 4.11e-06 54.7 COG0305@1|root,COG0305@2|Bacteria,2GKXQ@201174|Actinobacteria,4DXQ3@85010|Pseudonocardiales 201174|Actinobacteria L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_230254_7 525909.Afer_1986 1.63e-08 67.8 COG2385@1|root,COG4733@1|root,COG2385@2|Bacteria,COG4733@2|Bacteria,2HGMX@201174|Actinobacteria,4CNMU@84992|Acidimicrobiia 84992|Acidimicrobiia D Peptidase A4 family - - - - - - - - - - - - Peptidase_A4 k59_25565_2 105154.Q9MBU6_9VIRU 1.85e-197 569.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_25565_4 1385658.U5KNR1_9VIRU 7.16e-66 216.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_251839_11 1288484.APCS01000031_gene2346 3.25e-93 301.0 COG5362@1|root,COG5362@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Terminase_6C k59_45792_1 1120971.AUCA01000053_gene371 1.64e-86 262.0 COG0863@1|root,COG0863@2|Bacteria,1UZIN@1239|Firmicutes,4HU16@91061|Bacilli 91061|Bacilli L DNA methylase - - - - - - - - - - - - N6_N4_Mtase k59_293125_1 351348.Maqu_4187 1.11e-19 89.0 COG0675@1|root,COG0675@2|Bacteria,1MUU0@1224|Proteobacteria,1RS1J@1236|Gammaproteobacteria,46A8F@72275|Alteromonadaceae 1236|Gammaproteobacteria L Probable transposase - - - ko:K07496 - - - - ko00000 - - - HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon k59_540470_1 391603.FBALC1_10962 2.46e-17 92.0 COG1361@1|root,COG2304@1|root,COG3209@1|root,COG4257@1|root,COG1361@2|Bacteria,COG2304@2|Bacteria,COG3209@2|Bacteria,COG4257@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ7S@117743|Flavobacteriia 976|Bacteroidetes M SPTR CHU large protein - - - - - - - - - - - - CHU_C,Calx-beta,DUF11,HYR,SprB k59_520111_2 478749.BRYFOR_08560 3.75e-37 143.0 COG3378@1|root,COG3378@2|Bacteria 2|Bacteria KL Phage plasmid primase P4 family - - - ko:K06919 - - - - ko00000 - - - D5_N,DUF3854,P22_AR_N,Pox_D5 k59_272245_1 65093.PCC7418_0988 3.73e-06 53.5 COG1573@1|root,COG1573@2|Bacteria,1FZYH@1117|Cyanobacteria 1117|Cyanobacteria L Uracil-DNA glycosylase - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k59_209562_3 1354303.M917_0161 3.34e-76 243.0 28HEE@1|root,2Z7QU@2|Bacteria,1MXU6@1224|Proteobacteria,1RZSJ@1236|Gammaproteobacteria,3NJ4Z@468|Moraxellaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF932) - - - - - - - - - - - - DUF932 k59_209562_4 1172562.HCN_0694 8.09e-08 52.4 COG1089@1|root,COG1089@2|Bacteria,1MUX0@1224|Proteobacteria,42KZY@68525|delta/epsilon subdivisions,2YMQF@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria M Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose gmd - 4.2.1.47 ko:K01711 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R00888 RC00402 ko00000,ko00001,ko01000 - - - GDP_Man_Dehyd k59_6440_1 1234888.K0A2J2_9VIRU 3.05e-84 271.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_498183_1 284031.JNXD01000012_gene6461 3.74e-24 107.0 COG1200@1|root,COG1200@2|Bacteria,2GKA3@201174|Actinobacteria 201174|Actinobacteria L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge,tRNA_anti-codon k59_339966_3 1234888.K0A2J2_9VIRU 1.23e-72 238.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_70892_1 1382306.JNIM01000001_gene2562 8.17e-05 53.1 COG0209@1|root,COG1372@1|root,COG0209@2|Bacteria,COG1372@2|Bacteria,2G5PW@200795|Chloroflexi 200795|Chloroflexi F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrdA - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Intein_splicing,Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD k59_524929_6 879630.E1A1X2_9CAUD 3.55e-67 224.0 4QF57@10239|Viruses,4QVID@35237|dsDNA viruses no RNA stage,4QSP7@28883|Caudovirales,4QIC6@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_545963_2 997296.PB1_10744 4.81e-05 54.7 COG0457@1|root,COG0463@1|root,COG0457@2|Bacteria,COG0463@2|Bacteria,1TQEM@1239|Firmicutes,4H9X9@91061|Bacilli,1ZCYT@1386|Bacillus 91061|Bacilli M COG0463 Glycosyltransferases involved in cell wall biogenesis - GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009403,GO:0009404,GO:0009987,GO:0016740,GO:0016757,GO:0016999,GO:0017000,GO:0017144,GO:0018193,GO:0018198,GO:0018240,GO:0018280,GO:0019538,GO:0019748,GO:0030152,GO:0030650,GO:0030651,GO:0034641,GO:0034645,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043413,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044550,GO:0046224,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - - - - - - - - - - Glycos_transf_2,TPR_16 k59_10611_3 665950.HMPREF1025_01961 1.91e-150 438.0 COG0553@1|root,COG0553@2|Bacteria,1TS9W@1239|Firmicutes,24CGX@186801|Clostridia 186801|Clostridia KL Helicase conserved C-terminal domain - - - - - - - - - - - - - k59_10611_5 742740.HMPREF9474_02280 8.07e-33 116.0 2CGGB@1|root,32UNH@2|Bacteria,1VD9W@1239|Firmicutes,24MWC@186801|Clostridia,2235P@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_10611_6 742740.HMPREF9474_02279 2.77e-82 248.0 29YRZ@1|root,30KMY@2|Bacteria,1V4Y4@1239|Firmicutes,24HPY@186801|Clostridia,221XY@1506553|Lachnoclostridium 186801|Clostridia S Protein of unknown function (DUF2800) - - - - - - - - - - - - DUF2800 k59_10611_7 742733.HMPREF9469_05039 1.37e-261 760.0 28JED@1|root,2Z98K@2|Bacteria,1TW1U@1239|Firmicutes,24CFD@186801|Clostridia,2226E@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - GerE k59_485292_1 226185.EF_1672 6e-25 108.0 COG4591@1|root,COG4591@2|Bacteria,1UIYX@1239|Firmicutes,4ISXR@91061|Bacilli,4B5XG@81852|Enterococcaceae 91061|Bacilli M MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k59_525763_1 596153.Alide_1431 2.26e-66 223.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2VNHP@28216|Betaproteobacteria,4AC68@80864|Comamonadaceae 28216|Betaproteobacteria S Terminase - - - - - - - - - - - - Terminase_1 k59_133752_3 1122175.ATXU01000006_gene1936 9.07e-14 77.4 COG3723@1|root,COG3723@2|Bacteria,2II5R@201174|Actinobacteria,4FPDV@85023|Microbacteriaceae 201174|Actinobacteria L RecT family - - - - - - - - - - - - RecT k59_10621_1 1618236.A0A0C5IB23_9CIRC 7.32e-33 127.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_238391_1 10726.Q6QGN6_BPT5 3.94e-37 132.0 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales,4QKM7@10699|Siphoviridae 10699|Siphoviridae S HNH endonuclease - - - - - - - - - - - - - k59_655805_2 1692244.A0A0K1RLR5_9CIRC 4.89e-26 110.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_655805_3 1618247.A0A0C5IMK7_9CIRC 3.88e-10 65.5 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_403665_1 105154.Q9MBU6_9VIRU 1.56e-22 96.3 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_552639_1 1354722.JQLS01000008_gene1424 0.000341 53.5 COG3391@1|root,COG3391@2|Bacteria 2|Bacteria CO amine dehydrogenase activity - - - - - - - - - - - - EGF_3,Fibrinogen_C,Trypsin,VCBS k59_301812_3 1307834.BARL01000003_gene1602 5.63e-07 54.7 COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,2UF5C@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Ribosomal-protein-alanine acetyltransferase rimI - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1,Acetyltransf_10 k59_655808_2 1692249.A0A0K1RL40_9CIRC 1.85e-74 235.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_199205_1 155515.JP36_07460 1.91e-08 54.7 COG5614@1|root,COG5614@2|Bacteria,1N9Y5@1224|Proteobacteria,1SHES@1236|Gammaproteobacteria,1Y8ZN@135625|Pasteurellales 135625|Pasteurellales S Phage head-tail joining protein - - - - - - - - - - - - Phage_H_T_join k59_609219_1 986075.CathTA2_2439 1.97e-17 84.3 COG0270@1|root,COG0270@2|Bacteria,1TPNE@1239|Firmicutes,4HHQR@91061|Bacilli 91061|Bacilli H C-5 cytosine-specific DNA methylase - - - - - - - - - - - - DNA_methylase k59_630589_8 991.IW20_19930 8.03e-34 126.0 2CEKZ@1|root,2ZIEM@2|Bacteria,4P8Z3@976|Bacteroidetes,1IB1A@117743|Flavobacteriia,2NZFN@237|Flavobacterium 976|Bacteroidetes - - - - - - - - - - - - - - - k59_630589_9 1347393.HG726022_gene3579 0.000225 46.2 2EGZP@1|root,33ART@2|Bacteria,4NYAA@976|Bacteroidetes,2FVRR@200643|Bacteroidia,4AST7@815|Bacteroidaceae 976|Bacteroidetes S YopX protein - - - - - - - - - - - - YopX k59_630589_12 679189.HMPREF9019_0945 3.63e-13 68.6 2EHJD@1|root,33BB9@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - HTH_8 k59_630589_13 1123058.KB894219_gene152 2.34e-102 321.0 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,4NN30@976|Bacteroidetes 976|Bacteroidetes S Psort location Cytoplasmic, score 8.96 - - - - - - - - - - - - Terminase_6,Terminase_6C k59_216574_1 504474.cu1412 5.23e-10 69.3 COG4626@1|root,COG4626@2|Bacteria,2IB7D@201174|Actinobacteria 201174|Actinobacteria S Terminase - - - - - - - - - - - - Terminase_3,Terminase_6 k59_216574_2 1395516.PMO01_04985 2.13e-15 85.5 COG4695@1|root,COG4695@2|Bacteria,1MUP5@1224|Proteobacteria,1RPB0@1236|Gammaproteobacteria 1236|Gammaproteobacteria S portal protein - - - - - - - - - - - - Phage_portal k59_533580_1 1123355.JHYO01000004_gene2518 1.59e-23 112.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2TS19@28211|Alphaproteobacteria,36YIW@31993|Methylocystaceae 28211|Alphaproteobacteria F Ribonucleotide reductase, all-alpha domain nrdA - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - RNR_N,Ribonuc_red_lgC,Ribonuc_red_lgN k59_82534_1 935948.KE386495_gene1203 5.87e-24 105.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,42HQD@68295|Thermoanaerobacterales 186801|Clostridia KL SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,SNF2_N k59_410682_1 242861.Q6UYH2_9CAUD 7.68e-15 85.1 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QKNE@10699|Siphoviridae 10699|Siphoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_575091_1 1423144.Gal_04448 6.86e-25 111.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2TTEX@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Terminase - - - - - - - - - - - - Terminase_1 k59_247116_1 591158.SSMG_02772 1.47e-20 90.9 COG3409@1|root,COG3409@2|Bacteria,2GR1Q@201174|Actinobacteria 201174|Actinobacteria M N-Acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - CHAP,LysM,PG_binding_1 k59_349306_1 1406780.U5PWH9_9CAUD 4.97e-56 196.0 4QBY0@10239|Viruses,4QW35@35237|dsDNA viruses no RNA stage,4QQ4Q@28883|Caudovirales,4QNNN@10744|Podoviridae 10744|Podoviridae S UvrD-like helicase C-terminal domain - - - - - - - - - - - - - k59_533944_1 526218.Sterm_1409 1.71e-23 102.0 COG2887@1|root,COG2887@2|Bacteria,379RI@32066|Fusobacteria 32066|Fusobacteria L Protein of unknown function (DUF2800) - - - - - - - - - - - - DUF2800 k59_103121_1 1246459.KB898353_gene373 4.43e-55 222.0 COG1749@1|root,COG1749@2|Bacteria,1QWWE@1224|Proteobacteria,2TX6F@28211|Alphaproteobacteria,4BP3J@82115|Rhizobiaceae 28211|Alphaproteobacteria N Domain of unknown function (DUF4082) - - - - - - - - - - - - DUF4082 k59_103121_2 1206730.BAGA01000181_gene3003 1.53e-06 58.5 29WW4@1|root,30IHS@2|Bacteria,2H7TK@201174|Actinobacteria,4G08V@85025|Nocardiaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_287800_1 1692249.A0A0K1RL40_9CIRC 2.81e-56 189.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_247130_2 1381123.AYOD01000005_gene1290 2.9e-64 206.0 2CHRY@1|root,30Z9E@2|Bacteria,1RGQK@1224|Proteobacteria,2U9J0@28211|Alphaproteobacteria,43MIB@69277|Phyllobacteriaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - RecT k59_595431_1 935863.AWZR01000005_gene2346 9.41e-88 276.0 COG1961@1|root,COG1961@2|Bacteria,1MV0C@1224|Proteobacteria 1224|Proteobacteria L COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - - - - - - - - - - Recombinase,Resolvase,Zn_ribbon_recom k59_329072_1 886882.PPSC2_c1526 5.78e-24 109.0 COG5002@1|root,COG5002@2|Bacteria,1TPSK@1239|Firmicutes,4HD2N@91061|Bacilli,26R1F@186822|Paenibacillaceae 91061|Bacilli T Histidine kinase lisK - - - - - - - - - - - HAMP,HATPase_c,HisKA k59_329072_2 1423807.BACO01000071_gene2231 3.09e-08 55.5 COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,4H9KP@91061|Bacilli,3F61A@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulatory protein, C-terminal domain protein - - - ko:K07658 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C k59_21258_1 1306947.ARQD01000003_gene224 8.98e-36 135.0 COG1351@1|root,COG1351@2|Bacteria,2NPQ2@2323|unclassified Bacteria 2|Bacteria F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant thyX - 2.1.1.148 ko:K03465 ko00240,ko00670,ko01100,map00240,map00670,map01100 - R06613 RC00022,RC00332 ko00000,ko00001,ko01000 - - - HNH,Thy1 k59_452006_1 1234888.K0A2J2_9VIRU 3.84e-56 191.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_619609_2 1122138.AQUZ01000016_gene201 2.96e-07 50.4 2E39Y@1|root,32Y9G@2|Bacteria,2GQJA@201174|Actinobacteria,4DSBB@85009|Propionibacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - k59_517566_1 11082.PRO_0000037750 1.16e-89 281.0 4QBXT@10239|Viruses,4R138@439488|ssRNA viruses,4R0R1@35278|ssRNA positive-strand viruses no DNA stage 10239|Viruses K ATP-dependent helicase activity - GO:0001510,GO:0001959,GO:0001960,GO:0002682,GO:0002683,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003725,GO:0003727,GO:0003824,GO:0004482,GO:0004483,GO:0005488,GO:0005575,GO:0006139,GO:0006370,GO:0006396,GO:0006397,GO:0006508,GO:0006725,GO:0006807,GO:0006810,GO:0006897,GO:0006898,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008171,GO:0008173,GO:0008174,GO:0008233,GO:0008757,GO:0009451,GO:0009452,GO:0009605,GO:0009607,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009966,GO:0009968,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010646,GO:0010648,GO:0010941,GO:0016032,GO:0016070,GO:0016071,GO:0016192,GO:0016556,GO:0016740,GO:0016741,GO:0016787,GO:0018995,GO:0019012,GO:0019031,GO:0019048,GO:0019049,GO:0019050,GO:0019054,GO:0019058,GO:0019065,GO:0019068,GO:0019219,GO:0019222,GO:0019538,GO:0020012,GO:0023051,GO:0023057,GO:0030260,GO:0030430,GO:0030682,GO:0030683,GO:0031323,GO:0031324,GO:0031329,GO:0031330,GO:0031347,GO:0031348,GO:0032259,GO:0032991,GO:0032993,GO:0033592,GO:0033643,GO:0033646,GO:0033655,GO:0033668,GO:0034641,GO:0035821,GO:0036260,GO:0036265,GO:0036338,GO:0039502,GO:0039503,GO:0039526,GO:0039713,GO:0039714,GO:0042981,GO:0043067,GO:0043069,GO:0043170,GO:0043207,GO:0043412,GO:0043414,GO:0043487,GO:0043489,GO:0043656,GO:0043657,GO:0043900,GO:0043902,GO:0043903,GO:0044003,GO:0044068,GO:0044215,GO:0044216,GO:0044217,GO:0044237,GO:0044238,GO:0044260,GO:0044403,GO:0044409,GO:0044413,GO:0044414,GO:0044415,GO:0044419,GO:0044423,GO:0044501,GO:0044531,GO:0044532,GO:0044766,GO:0045069,GO:0045070,GO:0045088,GO:0045824,GO:0045934,GO:0046483,GO:0046718,GO:0046755,GO:0046762,GO:0046794,GO:0048518,GO:0048519,GO:0048523,GO:0048524,GO:0048583,GO:0048585,GO:0050690,GO:0050776,GO:0050777,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051252,GO:0051253,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051806,GO:0051807,GO:0051817,GO:0051828,GO:0051832,GO:0051833,GO:0051834,GO:0052027,GO:0052029,GO:0052031,GO:0052037,GO:0052040,GO:0052041,GO:0052150,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052248,GO:0052250,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052433,GO:0052490,GO:0052493,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0060147,GO:0060149,GO:0060255,GO:0060338,GO:0060339,GO:0060548,GO:0060759,GO:0060761,GO:0060966,GO:0060967,GO:0060968,GO:0060969,GO:0065007,GO:0065008,GO:0071704,GO:0072583,GO:0075109,GO:0075111,GO:0075112,GO:0075114,GO:0075136,GO:0075509,GO:0075512,GO:0075528,GO:0080009,GO:0080090,GO:0080134,GO:0090304,GO:0097159,GO:0097617,GO:0098657,GO:0106005,GO:0140096,GO:0140098,GO:1900368,GO:1900369,GO:1901360,GO:1901363,GO:1901564,GO:1902369,GO:1902579,GO:1903900,GO:1903902,GO:1990814,GO:1990904 - - - - - - - - - - - k59_4386_4 1122201.AUAZ01000017_gene2950 9.9e-110 330.0 COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,1RY1X@1236|Gammaproteobacteria,46BED@72275|Alteromonadaceae 1236|Gammaproteobacteria S associated with various cellular activities - - - - - - - - - - - - AAA,AAA_5 k59_4386_5 713586.KB900536_gene1133 3.7e-30 127.0 COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,1RXX2@1236|Gammaproteobacteria,1WX24@135613|Chromatiales 135613|Chromatiales S VWA-like domain (DUF2201) - - - - - - - - - - - - DUF2201,DUF2201_N k59_4386_8 942016.E9NIG2_9CAUD 2.43e-74 245.0 4QBY0@10239|Viruses,4QW35@35237|dsDNA viruses no RNA stage,4QQ4Q@28883|Caudovirales,4QNNN@10744|Podoviridae 10744|Podoviridae S UvrD-like helicase C-terminal domain - - - - - - - - - - - - - k59_4386_10 1112212.JH584235_gene3395 7.12e-35 132.0 COG0452@1|root,COG0756@1|root,COG0452@2|Bacteria,COG0756@2|Bacteria,1MVQP@1224|Proteobacteria,2TRN1@28211|Alphaproteobacteria,2K0N6@204457|Sphingomonadales 204457|Sphingomonadales H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine coaBC - 4.1.1.36,6.3.2.5 ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - - DFP,Flavoprotein k59_310950_1 1137745.H6WFW1_9CAUD 1.46e-14 82.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QI82@10662|Myoviridae 10662|Myoviridae S virus tail, fiber - GO:0005575,GO:0019012 - - - - - - - - - - - k59_86706_1 67356.KL575597_gene7671 2.86e-07 55.5 2EH1V@1|root,33ATU@2|Bacteria,2GU12@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_598608_1 857312.D9J0X5_9CAUD 1.02e-12 67.8 4QAQV@10239|Viruses,4QUPK@35237|dsDNA viruses no RNA stage,4QPCB@28883|Caudovirales,4QHX6@10662|Myoviridae 10662|Myoviridae S hydrolase activity - - - - - - - - - - - - - k59_598608_3 444158.MmarC6_0019 6.93e-44 160.0 COG0863@1|root,arCOG00115@2157|Archaea,2XWB2@28890|Euryarchaeota,23RT5@183939|Methanococci 183939|Methanococci L PFAM DNA methylase N-4 N-6 domain protein - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_352046_1 467481.B0VK09_9CAUD 2.18e-06 48.9 4QB0W@10239|Viruses,4QZQH@35237|dsDNA viruses no RNA stage,4QQW9@28883|Caudovirales,4QN19@10699|Siphoviridae 10699|Siphoviridae S Protein of unknown function (DUF1064) - - - - - - - - - - - - - k59_86713_1 1234888.K0A2J2_9VIRU 1.88e-43 158.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_24338_1 411471.SUBVAR_07088 9.94e-16 84.0 COG0739@1|root,COG0739@2|Bacteria,1VAC5@1239|Firmicutes,25E3G@186801|Clostridia 186801|Clostridia M Peptidase, M23 - - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M23 k59_460559_1 717606.PaecuDRAFT_3112 6.53e-91 286.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4H9YP@91061|Bacilli,26W69@186822|Paenibacillaceae 91061|Bacilli L SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,SNF2_N k59_296086_1 1449353.JQMQ01000005_gene4448 4.06e-31 126.0 COG0305@1|root,COG1066@1|root,COG0305@2|Bacteria,COG1066@2|Bacteria,2I8H0@201174|Actinobacteria 201174|Actinobacteria L AAA domain - - - - - - - - - - - - AAA_25,DnaB k59_461140_1 1437448.AZRT01000054_gene484 7.34e-09 61.6 COG0175@1|root,COG0175@2|Bacteria,1QZJ1@1224|Proteobacteria,2U233@28211|Alphaproteobacteria 28211|Alphaproteobacteria EH sulfate reduction - - - - - - - - - - - - - k59_484365_1 1294142.CINTURNW_1038 4.73e-18 87.0 COG1511@1|root,COG5412@1|root,COG1511@2|Bacteria,COG5412@2|Bacteria,1UZR9@1239|Firmicutes,25B3A@186801|Clostridia,36W7V@31979|Clostridiaceae 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_93254_1 756282.M4T1Q0_9CAUD 2.54e-15 80.9 4QG21@10239|Viruses,4QYV7@35237|dsDNA viruses no RNA stage,4QRQT@28883|Caudovirales,4QM3S@10699|Siphoviridae 10699|Siphoviridae S Phage terminase large subunit - - - - - - - - - - - - - k59_296680_3 10704.B4UTP0_BP163 3.06e-77 256.0 4QBV3@10239|Viruses,4QW0W@35237|dsDNA viruses no RNA stage,4QPPJ@28883|Caudovirales,4QKW5@10699|Siphoviridae 10699|Siphoviridae S Phage Terminase - - - - - - - - - - - - - k59_419601_1 1618260.A0A0C5I2C5_9CIRC 1.72e-86 266.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_275427_1 521393.JH806633_gene1271 9.5e-12 70.9 COG4626@1|root,COG4626@2|Bacteria,2IB7D@201174|Actinobacteria,4D4JH@85005|Actinomycetales 201174|Actinobacteria S Terminase - - - - - - - - - - - - Terminase_1 k59_398690_1 525309.HMPREF0494_0891 3.07e-58 199.0 COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,1TPHP@1239|Firmicutes,4HC9M@91061|Bacilli,3F5AA@33958|Lactobacillaceae 91061|Bacilli KL DNA methylase - - - - - - - - - - - - N6_N4_Mtase,ParBc k59_544893_6 1234888.K0A2J2_9VIRU 4.29e-146 430.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_212313_1 883156.HMPREF9282_00934 4.37e-31 125.0 COG2887@1|root,COG2887@2|Bacteria,1TPIC@1239|Firmicutes,4H2UC@909932|Negativicutes 909932|Negativicutes L Psort location Cytoplasmic, score 8.96 - - - - - - - - - - - - DUF2800 k59_212313_2 1562701.BBOF01000081_gene242 5.46e-45 154.0 2AHFY@1|root,317T8@2|Bacteria,1PZ6Y@1224|Proteobacteria,2W3DA@28216|Betaproteobacteria 28216|Betaproteobacteria S Protein of unknown function (DUF2815) - - - - - - - - - - - - DUF2815 k59_484394_2 529709.PYCH_00150 1.41e-10 63.9 COG0464@1|root,arCOG01308@2157|Archaea,2XSYR@28890|Euryarchaeota,243CC@183968|Thermococci 183968|Thermococci D Cell division protein 48 (CDC48) N-terminal domain - - - ko:K13525 ko04141,ko05134,map04141,map05134 M00400,M00403 - - ko00000,ko00001,ko00002,ko03019,ko04131,ko04147 3.A.16.1 - - AAA,CDC48_2,CDC48_N,Vps4_C k59_461185_1 1165094.RINTHH_3920 2.25e-59 195.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_132994_1 266265.Bxe_A3052 2.64e-07 59.3 COG5283@1|root,COG5283@2|Bacteria,1QY47@1224|Proteobacteria,2WHBB@28216|Betaproteobacteria,1KIK8@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_10061_2 1121904.ARBP01000033_gene3202 1.95e-34 127.0 COG3409@1|root,COG3409@2|Bacteria,4NTD1@976|Bacteroidetes,47SRH@768503|Cytophagia 976|Bacteroidetes M N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - Amidase_2,PG_binding_1 k59_301509_1 1195073.I6WB45_9CAUD 2.4e-10 66.2 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QNBD@10744|Podoviridae 10744|Podoviridae S outer membrane - - - - - - - - - - - - - k59_52505_1 1476391.X5KCB6_9CAUD 3.51e-136 427.0 4QAKM@10239|Viruses,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_75615_1 1235797.C816_01614 4.02e-25 110.0 COG0270@1|root,COG0270@2|Bacteria,1V3W2@1239|Firmicutes,24HK1@186801|Clostridia 186801|Clostridia L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K17398 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko03032,ko03036 - - - DNA_methylase k59_15239_2 575540.Isop_2447 8.48e-16 73.9 2DTQ9@1|root,33M9R@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_113321_1 265072.Mfla_2685 1.25e-24 118.0 COG4733@1|root,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria,2VJEP@28216|Betaproteobacteria 28216|Betaproteobacteria NT Phage-related protein, tail - - - - - - - - - - - - DUF1983,Phage-tail_3 k59_261292_1 911045.PSE_3620 1.13e-08 63.2 COG0457@1|root,COG0741@1|root,COG0457@2|Bacteria,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,2TRDB@28211|Alphaproteobacteria 28211|Alphaproteobacteria M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) slt - - ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 - SLT k59_466828_1 485916.Dtox_3913 2.58e-40 147.0 2BCCI@1|root,325XX@2|Bacteria,1URXQ@1239|Firmicutes,259VG@186801|Clostridia,263Q9@186807|Peptococcaceae 186801|Clostridia S Putative amidoligase enzyme - - - - - - - - - - - - Amidoligase_2 k59_466828_3 1226322.HMPREF1545_02202 1.19e-21 92.8 COG2105@1|root,COG2105@2|Bacteria,1VDAD@1239|Firmicutes,24G9Y@186801|Clostridia,2N7KA@216572|Oscillospiraceae 186801|Clostridia S Gamma-glutamyl cyclotransferase, AIG2-like - - - - - - - - - - - - AIG2_2,GGACT k59_588816_1 1234888.K0A2J2_9VIRU 9.43e-86 275.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_588816_6 2003327.CAPSD_BPCHP 7.36e-18 84.3 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_425333_2 1449351.RISW2_21770 9.08e-13 75.9 COG1196@1|root,COG3941@1|root,COG1196@2|Bacteria,COG3941@2|Bacteria 2|Bacteria O tape measure - - - - - - - - - - - - PhageMin_Tail,TMP_2,Tape_meas_lam_C k59_655855_2 1692259.A0A0K1RL59_9CIRC 7.07e-30 122.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_119683_1 1140001.I571_00069 9.08e-22 96.3 28KEB@1|root,2ZA0K@2|Bacteria,1V14E@1239|Firmicutes,4HNU7@91061|Bacilli,4B291@81852|Enterococcaceae 91061|Bacilli S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - - k59_594560_2 1385658.U5KPZ6_9VIRU 8.34e-150 436.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_327767_1 1123288.SOV_1c10590 4.8e-14 77.8 COG3378@1|root,COG3378@2|Bacteria,1TQP9@1239|Firmicutes,4H4C8@909932|Negativicutes 909932|Negativicutes S D5 N terminal like - - - - - - - - - - - - D5_N,Pox_D5 k59_224525_23 1096546.WYO_0164 4.1e-62 226.0 COG0749@1|root,COG0749@2|Bacteria,1MWX7@1224|Proteobacteria 1224|Proteobacteria L COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A,DNA_pol_A_exo1 k59_122100_1 1609634.A0A0C5AFV4_9VIRU 2.3e-80 264.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_122100_6 2003327.CAPSD_BPCHP 2.9e-17 84.3 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_224634_1 459349.CLOAM1507 9.39e-12 69.3 COG0863@1|root,COG0863@2|Bacteria 2|Bacteria L N-4 methylation of cytosine - - 2.1.1.113,2.1.1.72 ko:K00571,ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_122130_1 992406.RIA_1959 5.58e-17 84.3 COG4974@1|root,COG4974@2|Bacteria,4NGE1@976|Bacteroidetes,1HY1D@117743|Flavobacteriia 976|Bacteroidetes L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_int_SAM_4,Phage_integrase k59_60458_1 997350.HMPREF9129_2139 2.51e-25 104.0 COG0302@1|root,COG0302@2|Bacteria,1TRNM@1239|Firmicutes,24867@186801|Clostridia,22ICG@1570339|Peptoniphilaceae 186801|Clostridia F GTP cyclohydrolase 1 folE - 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydroI k59_122175_1 1169152.AXVD01000040_gene922 2.93e-18 91.3 COG0326@1|root,COG0326@2|Bacteria,2H6C2@201174|Actinobacteria 201174|Actinobacteria O Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - HATPase_c_3 k59_515245_1 6669.EFX83336 1.59e-20 95.1 COG1087@1|root,KOG1371@2759|Eukaryota,38C46@33154|Opisthokonta,3BFFH@33208|Metazoa,3CTIM@33213|Bilateria,41TFK@6656|Arthropoda 33208|Metazoa Q coenzyme binding. It is involved in the biological process described with galactose metabolic process - GO:0002164,GO:0002376,GO:0002520,GO:0003674,GO:0003824,GO:0003974,GO:0003978,GO:0005975,GO:0005996,GO:0006012,GO:0007275,GO:0008150,GO:0008152,GO:0009791,GO:0016853,GO:0016854,GO:0016857,GO:0019318,GO:0030097,GO:0032501,GO:0032502,GO:0035166,GO:0035167,GO:0044238,GO:0044281,GO:0048513,GO:0048534,GO:0048542,GO:0048569,GO:0048731,GO:0048732,GO:0048856,GO:0071704 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd k59_268761_4 266762.HQ36_02045 1.48e-17 89.4 COG0749@1|root,COG0749@2|Bacteria,4PK8J@976|Bacteroidetes,2FU9T@200643|Bacteroidia 976|Bacteroidetes L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity - - - - - - - - - - - - DNA_pol_A k59_596454_1 1538804.A0A088F6T3_9CAUD 2.66e-151 455.0 4QAKM@10239|Viruses,4QPEF@28883|Caudovirales,4QKNE@10699|Siphoviridae 10699|Siphoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_576301_1 246197.MXAN_1209 6.15e-61 216.0 COG5545@1|root,COG5545@2|Bacteria,1MVGK@1224|Proteobacteria 1224|Proteobacteria D virulence-associated E family protein - - - ko:K06919 - - - - ko00000 - - - PriCT_2,Prim-Pol,Toprim_3,VirE k59_186695_1 1054460.SPPN_00145 4.3e-06 53.1 2CWXD@1|root,32T0J@2|Bacteria,1V83I@1239|Firmicutes,4HPQE@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k59_104099_1 121225.PHUM577340-PA 7.15e-09 62.4 COG5049@1|root,KOG2045@2759|Eukaryota,38DKU@33154|Opisthokonta,3BEVP@33208|Metazoa,3CUYH@33213|Bilateria,41TYE@6656|Arthropoda,3SHZV@50557|Insecta,3E99H@33342|Paraneoptera 33208|Metazoa DL 5'-3' exoribonuclease XRN1 GO:0000003,GO:0000184,GO:0000291,GO:0000723,GO:0000932,GO:0000956,GO:0001700,GO:0002009,GO:0002151,GO:0002165,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004534,GO:0004540,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006396,GO:0006401,GO:0006402,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0007049,GO:0007275,GO:0007276,GO:0007283,GO:0007391,GO:0007444,GO:0007472,GO:0007476,GO:0007552,GO:0007560,GO:0007568,GO:0007569,GO:0008150,GO:0008152,GO:0008334,GO:0008340,GO:0008409,GO:0009056,GO:0009057,GO:0009611,GO:0009653,GO:0009790,GO:0009791,GO:0009792,GO:0009886,GO:0009887,GO:0009888,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009987,GO:0010259,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010603,GO:0010605,GO:0010607,GO:0010608,GO:0010629,GO:0010639,GO:0010941,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0016246,GO:0016331,GO:0016441,GO:0016458,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017148,GO:0019219,GO:0019222,GO:0019439,GO:0019953,GO:0022414,GO:0030425,GO:0031047,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031333,GO:0032200,GO:0032204,GO:0032205,GO:0032210,GO:0032211,GO:0032268,GO:0032269,GO:0032501,GO:0032502,GO:0032504,GO:0032991,GO:0033043,GO:0033044,GO:0034248,GO:0034249,GO:0034428,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0035107,GO:0035114,GO:0035120,GO:0035194,GO:0035220,GO:0035239,GO:0035295,GO:0035770,GO:0036464,GO:0036477,GO:0040008,GO:0040029,GO:0042060,GO:0042592,GO:0042981,GO:0042995,GO:0043005,GO:0043025,GO:0043066,GO:0043067,GO:0043069,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043254,GO:0043487,GO:0043488,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044297,GO:0044424,GO:0044444,GO:0044463,GO:0044464,GO:0044703,GO:0045202,GO:0045570,GO:0045572,GO:0045927,GO:0045934,GO:0046483,GO:0046528,GO:0046529,GO:0046620,GO:0046622,GO:0046700,GO:0048232,GO:0048513,GO:0048518,GO:0048519,GO:0048523,GO:0048563,GO:0048569,GO:0048598,GO:0048609,GO:0048638,GO:0048639,GO:0048707,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048856,GO:0048869,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051094,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051239,GO:0051240,GO:0051246,GO:0051248,GO:0051252,GO:0051276,GO:0051321,GO:0051704,GO:0051880,GO:0060249,GO:0060255,GO:0060429,GO:0060548,GO:0060562,GO:0061013,GO:0065007,GO:0065008,GO:0070034,GO:0070481,GO:0071025,GO:0071027,GO:0071028,GO:0071044,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097447,GO:0097458,GO:0120025,GO:0120038,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902115,GO:1902116,GO:1903311,GO:1904356,GO:1904357,GO:1990904,GO:2000026,GO:2000112,GO:2000113,GO:2000278,GO:2000279,GO:2001251 - ko:K12618 ko03008,ko03018,map03008,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03016,ko03019,ko03036 - - - XRN_N k59_535530_1 1385658.U5KNR1_9VIRU 4.09e-84 263.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_22429_1 1556290.A0A0A0RQP8_9CAUD 4.35e-56 204.0 4QBG4@10239|Viruses,4QRSK@28883|Caudovirales,4QKVU@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_63436_1 565034.BHWA1_00556 6.54e-43 150.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase - - - - - - - - - - - - MetW,Methyltransf_11,Methyltransf_23 k59_474263_1 360910.BAV1474 4.5e-15 79.7 COG3979@1|root,COG3979@2|Bacteria,1RGTZ@1224|Proteobacteria 1224|Proteobacteria O Transposase - - - - - - - - - - - - - k59_432523_1 428125.CLOLEP_01422 8.28e-06 50.4 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia,3WN92@541000|Ruminococcaceae 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_515270_1 172088.AUGA01000082_gene6213 1.75e-05 48.1 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,2U6BJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S TIGRFAM phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_432529_2 926550.CLDAP_02830 1.7e-37 132.0 COG2131@1|root,COG2131@2|Bacteria,2G7AC@200795|Chloroflexi 200795|Chloroflexi F MafB19-like deaminase - - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 k59_227354_2 80637.XP_007762595.1 6.34e-19 87.4 COG2131@1|root,KOG3127@2759|Eukaryota,38HPY@33154|Opisthokonta,3NVNV@4751|Fungi,3V00Z@5204|Basidiomycota,228PT@155619|Agaricomycetes 4751|Fungi F Cytidine and deoxycytidylate deaminase zinc-binding region DCD1 GO:0003674,GO:0003824,GO:0004132,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006231,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009157,GO:0009162,GO:0009165,GO:0009176,GO:0009177,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046073,GO:0046078,GO:0046385,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 k59_166075_4 1429916.X566_07715 8.85e-12 75.1 COG0582@1|root,COG0582@2|Bacteria,1N2H9@1224|Proteobacteria,2TS7K@28211|Alphaproteobacteria,3JWPB@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_3,Phage_int_SAM_3,Phage_integrase k59_412171_1 1234888.K0A2J2_9VIRU 2.55e-44 160.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_515293_1 76869.PputGB1_1761 3.52e-23 102.0 2DNU8@1|root,32Z5M@2|Bacteria,1RGT6@1224|Proteobacteria,1S5HA@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - Peptidase_S74 k59_555893_1 1408433.JHXV01000042_gene1444 3.68e-07 57.4 COG3209@1|root,COG3209@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ6N@117743|Flavobacteriia,2PC6H@246874|Cryomorphaceae 976|Bacteroidetes M SPTR CHU large protein - - - - - - - - - - - - CHU_C,SprB k59_535925_2 3218.PP1S324_39V6.1 1.51e-17 94.7 KOG1037@1|root,KOG1037@2759|Eukaryota,37M1M@33090|Viridiplantae,3GF90@35493|Streptophyta 35493|Streptophyta KLO Poly (ADP-ribose) polymerase PARP2 GO:0000726,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576 2.4.2.30 ko:K10798 ko03410,ko04210,ko04212,ko04214,ko04217,map03410,map04210,map04212,map04214,map04217 M00296 - - ko00000,ko00001,ko00002,ko01000,ko03032,ko03036,ko03400 - - - PARP,PARP_reg,SAP,WGR k59_642163_2 1173709.M3VMK9_9CIRC 6.36e-55 179.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_415088_1 1788455.A0A190WHF5_9CIRC 5.82e-14 77.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_539463_1 105154.Q9MBU3_9VIRU 2.2e-18 84.0 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_539463_2 1283300.ATXB01000002_gene2532 3.02e-29 110.0 COG3772@1|root,COG3772@2|Bacteria,1N0ZQ@1224|Proteobacteria,1S9AE@1236|Gammaproteobacteria 1236|Gammaproteobacteria S lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_25096_2 1038859.AXAU01000001_gene3739 1.6e-51 189.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,2TSF9@28211|Alphaproteobacteria,3JRJJ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_25096_6 697281.Mahau_0077 2.51e-19 99.0 COG0507@1|root,COG0507@2|Bacteria,1TQWH@1239|Firmicutes,24A8I@186801|Clostridia,42HVJ@68295|Thermoanaerobacterales 186801|Clostridia L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD - - - - - - - - - - - - - k59_292526_3 1114959.SZMC14600_22475 2.74e-23 94.7 arCOG05626@1|root,30CNA@2|Bacteria,2I38B@201174|Actinobacteria,4EDYI@85010|Pseudonocardiales 201174|Actinobacteria - - - - - - - - - - - - - - - k59_271714_1 1088869.GMO_11580 1.04e-05 48.1 COG3740@1|root,COG3740@2|Bacteria,1NBQ9@1224|Proteobacteria,2UK6T@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Caudovirus prohead serine protease - - - - - - - - - - - - Peptidase_S78 k59_457218_2 1429767.W6B150_9CAUD 4.44e-53 189.0 4QF3C@10239|Viruses,4QWIA@35237|dsDNA viruses no RNA stage,4QU4U@28883|Caudovirales,4QNNQ@10744|Podoviridae 10744|Podoviridae S host cell wall - - - - - - - - - - - - - k59_189916_2 1265502.KB905977_gene538 3.28e-09 65.5 28KRA@1|root,2ZA8W@2|Bacteria,1R7WX@1224|Proteobacteria,2W0N1@28216|Betaproteobacteria 1265502.KB905977_gene538|- - - - - - - - - - - - - - - - k59_519401_1 1556290.A0A0A0RT35_9CAUD 8.87e-60 197.0 4QAWG@10239|Viruses,4QPII@28883|Caudovirales,4QKWY@10699|Siphoviridae 10699|Siphoviridae S DNA helicase activity - - - - - - - - - - - - - k59_558737_3 402612.FP1997 8.77e-24 107.0 COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes,1HXV0@117743|Flavobacteriia,2NVCP@237|Flavobacterium 976|Bacteroidetes E Glutamine amidotransferase domain asnB - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 k59_88183_2 1357279.N018_13055 3.86e-74 233.0 2E0AI@1|root,32VXW@2|Bacteria,1N2A1@1224|Proteobacteria,1SAFV@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_70399_2 1618248.A0A0C5IB82_9CIRC 3.12e-83 259.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_92720_3 760568.Desku_1126 8.27e-35 130.0 COG1475@1|root,COG4725@1|root,COG1475@2|Bacteria,COG4725@2|Bacteria,1TT7N@1239|Firmicutes,24D10@186801|Clostridia 186801|Clostridia L ParB-like nuclease domain - - - - - - - - - - - - ParBc k59_339284_2 1416009.V9VG35_9CAUD 1.17e-23 101.0 4QDXM@10239|Viruses,4QWIX@35237|dsDNA viruses no RNA stage,4QQF6@28883|Caudovirales,4QNXH@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_378012_1 242861.Q6UYH2_9CAUD 2.68e-45 169.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QKNE@10699|Siphoviridae 10699|Siphoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_193635_1 227470.Q76YS7_9CAUD 1.8e-16 83.2 4QC5J@10239|Viruses,4QXP7@35237|dsDNA viruses no RNA stage,4QTBX@28883|Caudovirales,4QJQT@10662|Myoviridae 10662|Myoviridae S Domain of unknown function (DUF2828) - - - - - - - - - - - - - k59_624750_1 457424.BFAG_02390 4.36e-52 173.0 COG1235@1|root,COG1235@2|Bacteria,4NDVI@976|Bacteroidetes,2FSEU@200643|Bacteroidia,4AQT2@815|Bacteroidaceae 976|Bacteroidetes S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B,Lactamase_B_2 k59_92735_1 340177.Cag_0702 7.27e-42 143.0 COG3772@1|root,COG3772@2|Bacteria 2|Bacteria S cytolysis by virus of host cell - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_356063_2 379066.GAU_1425 3.59e-13 70.9 COG0472@1|root,COG0472@2|Bacteria,1ZT4Y@142182|Gemmatimonadetes 142182|Gemmatimonadetes M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan mraY - 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - - Glycos_transf_4 k59_356064_1 1476391.X5L4L4_9CAUD 1.72e-17 84.0 4QEWC@10239|Viruses,4QYMK@35237|dsDNA viruses no RNA stage,4QUH4@28883|Caudovirales,4QP0K@10744|Podoviridae 10744|Podoviridae S signal transduction - - - - - - - - - - - - - k59_173962_2 1286171.EAL2_c13910 1.52e-24 104.0 COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,2480W@186801|Clostridia,25V6T@186806|Eubacteriaceae 186801|Clostridia L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 k59_603311_9 1463857.JOFZ01000008_gene728 9.23e-21 97.4 COG0739@1|root,COG0739@2|Bacteria,2GXEC@201174|Actinobacteria 201174|Actinobacteria M peptidase - - - - - - - - - - - - Peptidase_M23 k59_9718_4 1235835.C814_02364 2.54e-32 122.0 COG1961@1|root,COG1961@2|Bacteria,1UZT3@1239|Firmicutes,25BHM@186801|Clostridia,3WS5N@541000|Ruminococcaceae 186801|Clostridia L Resolvase, N terminal domain - - - - - - - - - - - - HTH_7,Resolvase k59_483845_1 1618240.A0A0C5IMJ1_9CIRC 1.29e-114 334.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_484540_2 716928.AJQT01000109_gene1196 2.6e-29 114.0 COG2520@1|root,COG2520@2|Bacteria 2|Bacteria J tRNA (guanine(37)-N(1))-methyltransferase activity XK27_03530 - - - - - - - - - - - Methyltransf_21,rRNA_methylase k59_545064_1 926550.CLDAP_28640 5.16e-67 214.0 COG0540@1|root,COG0540@2|Bacteria,2G6GU@200795|Chloroflexi 200795|Chloroflexi F Belongs to the ATCase OTCase family pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N k59_545064_2 267747.PPA2128 2.14e-18 86.7 COG0018@1|root,COG0018@2|Bacteria,2GKQ3@201174|Actinobacteria,4DNTZ@85009|Propionibacteriales 201174|Actinobacteria J Arginyl tRNA synthetase N terminal dom argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d k59_174465_1 929712.KI912613_gene4078 0.000264 51.2 28N3Q@1|root,2ZB9C@2|Bacteria,2GM98@201174|Actinobacteria 201174|Actinobacteria S Pectate lyase superfamily protein - - - - - - - - - - - - Beta_helix,Pectate_lyase_3 k59_448221_2 742722.HMPREF9463_01016 9.07e-09 55.5 COG0234@1|root,COG0234@2|Bacteria,2IKTH@201174|Actinobacteria,4CW90@84998|Coriobacteriia 84998|Coriobacteriia O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS - - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 k59_301080_1 591001.Acfer_1093 4.83e-63 237.0 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,4H28F@909932|Negativicutes 909932|Negativicutes L Psort location Cytoplasmic, score 8.96 - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_403067_1 1123252.ATZF01000001_gene1182 3.7e-08 58.9 COG0358@1|root,COG0358@2|Bacteria 2|Bacteria L DNA primase activity - - 3.6.4.12 ko:K02316,ko:K17680 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03029,ko03032 - - - DUF3991,DnaB_C,Toprim_2,Toprim_3,Toprim_N,zf-CHC2 k59_655770_2 1379692.S5SXY7_9CIRC 4.37e-47 168.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_608973_1 565045.NOR51B_255 2.29e-37 135.0 COG0582@1|root,COG0582@2|Bacteria,1QJCD@1224|Proteobacteria,1THBF@1236|Gammaproteobacteria,1JBPV@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_integrase k59_424741_3 1352941.M877_05070 0.000153 44.7 2CC1Y@1|root,32RUK@2|Bacteria,2IQ4Q@201174|Actinobacteria 201174|Actinobacteria K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA whmD - - ko:K18955 - - - - ko00000,ko03000 - - - Whib k59_75663_1 935836.JAEL01000062_gene2096 8.12e-95 295.0 COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,4HB81@91061|Bacilli,1ZC50@1386|Bacillus 91061|Bacilli L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB - - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB k59_655778_1 1391037.T1YRW0_9VIRU 4.8e-06 53.1 4QB6C@10239|Viruses 10239|Viruses L Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_608995_2 189753.AXAS01000008_gene6703 4.84e-25 110.0 COG3409@1|root,COG3926@1|root,COG3409@2|Bacteria,COG3926@2|Bacteria,1MVXW@1224|Proteobacteria,2TT3H@28211|Alphaproteobacteria,3K0NK@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Predicted Peptidoglycan domain - - - ko:K17733 - - - - ko00000,ko01000,ko01002,ko01011 - - - Glyco_hydro_108,PG_binding_1,PG_binding_3,VanY k59_113382_1 749222.Nitsa_1810 5.69e-79 241.0 2C2E9@1|root,32RAA@2|Bacteria,1RF5M@1224|Proteobacteria,433I8@68525|delta/epsilon subdivisions 1224|Proteobacteria - - - - - - - - - - - - - - - k59_655779_2 1732201.A0A0N9N7I3_9CIRC 1.7e-37 141.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_75705_1 906888.JCM19314_1159 1.07e-31 115.0 COG4696@1|root,COG4696@2|Bacteria,4NNW2@976|Bacteroidetes,1I23U@117743|Flavobacteriia,3HKD6@363408|Nonlabens 976|Bacteroidetes S Phosphoribosyl-ATP pyrophosphohydrolase - - - - - - - - - - - - PRA-PH k59_34331_2 198110.B3FK10_9CAUD 5.38e-29 116.0 4QBHW@10239|Viruses,4QVHG@35237|dsDNA viruses no RNA stage,4QTT7@28883|Caudovirales,4QJZQ@10662|Myoviridae 10662|Myoviridae S sequence-specific DNA binding transcription factor activity - - - - - - - - - - - - - k59_34331_4 1287276.X752_25920 9.78e-19 80.5 2E5GW@1|root,3308F@2|Bacteria,1N8DS@1224|Proteobacteria,2UVDU@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknwon function (DUF3310) - - - - - - - - - - - - DUF3310 k59_491382_1 1120963.KB894518_gene2794 7.27e-96 306.0 COG0749@1|root,COG0749@2|Bacteria,1MWX7@1224|Proteobacteria,1S0Q1@1236|Gammaproteobacteria 1236|Gammaproteobacteria L ORF located using Glimmer RBSfinder - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A,DNA_pol_A_exo1 k59_491382_4 862908.BMS_1457 3.84e-33 120.0 COG1694@1|root,COG1694@2|Bacteria 2|Bacteria FG Mazg nucleotide pyrophosphohydrolase MA20_27270 - - - - - - - - - - - MazG k59_365690_2 714943.Mucpa_5960 1.05e-18 92.4 2D7QU@1|root,32TPH@2|Bacteria,4NT9J@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - k59_306938_1 751944.HALDL1_06755 7.62e-20 95.9 COG0417@1|root,arCOG00328@2157|Archaea,2XU1K@28890|Euryarchaeota,23RXE@183963|Halobacteria 183963|Halobacteria L COG0417 DNA polymerase elongation subunit (family B) polB1 - 2.7.7.7 ko:K02319 ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032 - - - DNA_pol_B,DNA_pol_B_exo1,Intein_splicing k59_119150_1 428125.CLOLEP_01422 1.26e-65 253.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia,3WN92@541000|Ruminococcaceae 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_306997_1 1126950.G9J1V7_9CAUD 2.06e-10 60.8 4QBE2@10239|Viruses,4R0FU@35237|dsDNA viruses no RNA stage,4QT8G@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_40568_2 1120919.AUBI01000025_gene3551 4.2e-10 59.7 COG1403@1|root,COG1403@2|Bacteria 2|Bacteria V endonuclease activity - - - - - - - - - - - - DUF222,HNH k59_40574_1 1286619.L7WSA3_9CIRC 2.73e-25 105.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_204823_1 1234880.K0A2H8_9CIRC 1.44e-39 148.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_409499_1 1117108.PAALTS15_09985 4.89e-26 120.0 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,4H9Z7@91061|Bacilli,26RQI@186822|Paenibacillaceae 91061|Bacilli L DNA polymerase - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_163118_3 105154.Q9MBU6_9VIRU 1.21e-138 419.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_163118_4 145579.H_BPPHM 1.61e-07 57.8 4QCA6@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_287055_2 305700.B447_10643 2.83e-25 100.0 COG2197@1|root,COG2197@2|Bacteria,1NA3X@1224|Proteobacteria,2VW90@28216|Betaproteobacteria 28216|Betaproteobacteria KT HNH endonuclease - - - - - - - - - - - - HNH_3 k59_59189_1 1321778.HMPREF1982_02859 1.91e-21 104.0 COG0749@1|root,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia,267MY@186813|unclassified Clostridiales 186801|Clostridia L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity - - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - DNA_pol_A,DNA_pol_A_exo1 k59_245541_3 1028806.GGE_2172 2.7e-19 100.0 COG1196@1|root,COG5281@1|root,COG1196@2|Bacteria,COG5281@2|Bacteria,1MX2R@1224|Proteobacteria,1SYI1@1236|Gammaproteobacteria 1236|Gammaproteobacteria D tape measure protein - - - - - - - - - - - - Phage_HK97_TLTM k59_59247_1 1121104.AQXH01000001_gene1461 2.09e-07 54.3 COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,1INNM@117747|Sphingobacteriia 976|Bacteroidetes K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released rpoD - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 k59_371567_1 1692250.A0A0K1RLR1_9CIRC 1.47e-86 268.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_350951_1 1234888.K0A2J2_9VIRU 1.88e-59 200.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_146133_5 665956.HMPREF1032_02279 3.19e-79 244.0 COG0192@1|root,COG0192@2|Bacteria,1TT9U@1239|Firmicutes,24D9Z@186801|Clostridia 186801|Clostridia H S-adenosylmethionine synthetase, N-terminal domain - - 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - - S-AdoMet_synt_N k59_412667_1 1187851.A33M_1721 3.21e-11 69.3 COG1475@1|root,COG2265@1|root,COG1475@2|Bacteria,COG2265@2|Bacteria,1QZRI@1224|Proteobacteria,2TYCY@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family - - - - - - - - - - - - - k59_227859_2 1096546.WYO_0171 1.46e-134 407.0 COG0553@1|root,COG0553@2|Bacteria,1PXS8@1224|Proteobacteria,2UAZ5@28211|Alphaproteobacteria 28211|Alphaproteobacteria KL COG0553 Superfamily II DNA RNA helicases, SNF2 family - - - - - - - - - - - - SNF2_N k59_638980_2 105154.Q9MBU3_9VIRU 4.38e-11 66.6 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_516110_37 1002809.SSIL_0813 4.16e-12 71.6 COG3935@1|root,COG3935@2|Bacteria,1TSHD@1239|Firmicutes,4HIGY@91061|Bacilli,26GB5@186818|Planococcaceae 91061|Bacilli L Conserved phage C-terminus (Phg_2220_C) - - - - - - - - - - - - Phage_rep_org_N,Phg_2220_C k59_516110_38 1304888.ATWF01000001_gene2300 6.13e-32 134.0 COG0305@1|root,COG0305@2|Bacteria,2GERT@200930|Deferribacteres 200930|Deferribacteres L Participates in initiation and elongation during chromosome replication - - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_516110_57 484770.UFO1_2472 1.72e-19 83.6 28P3F@1|root,32U60@2|Bacteria,1VDW0@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - k59_516110_60 445970.ALIPUT_00696 2.99e-25 118.0 COG1196@1|root,COG3941@1|root,COG1196@2|Bacteria,COG3941@2|Bacteria,4NF3E@976|Bacteroidetes,2FNYJ@200643|Bacteroidia 976|Bacteroidetes D Psort location OuterMembrane, score - - - - - - - - - - - - - k59_331549_1 691965.D4P7D8_9CAUD 1.26e-37 129.0 4QBBW@10239|Viruses,4QXCP@35237|dsDNA viruses no RNA stage,4QQ3N@28883|Caudovirales,4QN1X@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_331549_2 742733.HMPREF9469_05026 9.97e-88 265.0 28NM4@1|root,2ZBMQ@2|Bacteria,1V1QD@1239|Firmicutes,24G1B@186801|Clostridia,221N8@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_331549_3 1537917.JU82_06570 1.8e-58 187.0 2CGG9@1|root,2ZVSJ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_331549_4 691965.D4P7D9_9CAUD 1.23e-41 150.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_331549_6 428125.CLOLEP_01421 9.57e-47 154.0 2ARVA@1|root,31H70@2|Bacteria,1V7JT@1239|Firmicutes,24JPE@186801|Clostridia,3WP7W@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - HK97-gp10_like k59_331549_7 428125.CLOLEP_01422 2.93e-169 565.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia,3WN92@541000|Ruminococcaceae 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_331549_9 931626.Awo_c30930 7.51e-08 62.4 28K55@1|root,2Z9TX@2|Bacteria,1V0P7@1239|Firmicutes,24DCX@186801|Clostridia,25YTV@186806|Eubacteriaceae 186801|Clostridia S Siphovirus ReqiPepy6 Gp37-like protein - - - - - - - - - - - - Sipho_Gp37 k59_249459_1 1096546.WYO_0193 7.35e-17 79.3 28JC4@1|root,2Z96S@2|Bacteria,1RI8W@1224|Proteobacteria 1224|Proteobacteria S P22 coat protein-protein 5 domain protein - - - - - - - - - - - - - k59_556512_1 1234888.K0A2J2_9VIRU 7.05e-85 271.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_597476_1 1121926.AXWO01000004_gene1187 1.3e-20 94.0 2B815@1|root,3218Y@2|Bacteria,2H57E@201174|Actinobacteria 201174|Actinobacteria S Rad52/22 family double-strand break repair protein - - - - - - - - - - - - Rad52_Rad22 k59_253843_1 1283079.M1IPS2_9CAUD 9.31e-05 52.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QNBD@10744|Podoviridae 10744|Podoviridae S outer membrane - GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0008150,GO:0016032,GO:0016787,GO:0016798,GO:0019012,GO:0019058,GO:0019062,GO:0022610,GO:0044403,GO:0044406,GO:0044409,GO:0044411,GO:0044419,GO:0044423,GO:0044650,GO:0051701,GO:0051704,GO:0051828,GO:0051830,GO:0085027,GO:0098015,GO:0098024 - - - - - - - - - - - k59_622955_1 411460.RUMTOR_01356 2.1e-22 99.4 28JED@1|root,2Z98K@2|Bacteria,1TW1U@1239|Firmicutes,24CFD@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - GerE k59_622955_2 428125.CLOLEP_01399 9.25e-21 87.8 29YRZ@1|root,30KMY@2|Bacteria,1V4Y4@1239|Firmicutes,24HPY@186801|Clostridia,3WNNS@541000|Ruminococcaceae 186801|Clostridia S Protein of unknown function (DUF2800) - - - - - - - - - - - - DUF2800 k59_210674_1 1033737.CAEV01000029_gene296 7.79e-10 66.6 COG4695@1|root,COG4695@2|Bacteria,1TP8B@1239|Firmicutes,2497C@186801|Clostridia,36H1A@31979|Clostridiaceae 186801|Clostridia S Phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_108026_3 631362.Thi970DRAFT_01680 5.06e-17 79.7 COG4122@1|root,COG4122@2|Bacteria,1N5R0@1224|Proteobacteria,1SHSR@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Macrocin-O-methyltransferase (TylF) - - - - - - - - - - - - TylF k59_396467_1 1429912.V5R9A1_9CAUD 0.000366 48.5 4QB4T@10239|Viruses,4QYFG@35237|dsDNA viruses no RNA stage,4QR7K@28883|Caudovirales,4QN2T@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_459049_1 202955.BBND01000035_gene3071 2.99e-12 68.9 COG1961@1|root,COG1961@2|Bacteria,1R3XB@1224|Proteobacteria,1RSC2@1236|Gammaproteobacteria,3NKN4@468|Moraxellaceae 1236|Gammaproteobacteria L Resolvase, N terminal domain - - - ko:K14060 - - - - ko00000 - - - HTH_7,Resolvase k59_396482_1 1123237.Salmuc_03630 3.76e-37 135.0 COG1403@1|root,COG1403@2|Bacteria,1QE4E@1224|Proteobacteria 1224|Proteobacteria L HNH endonuclease - - - - - - - - - - - - HNH,HNH_5,RRXRR k59_542258_1 1517681.HW45_02510 5.41e-07 54.7 COG0582@1|root,COG0582@2|Bacteria,1N2H9@1224|Proteobacteria,1RY6S@1236|Gammaproteobacteria,1Y2DS@135623|Vibrionales 1236|Gammaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_3,Phage_int_SAM_3,Phage_integrase k59_337103_1 1120978.KB894087_gene430 1.01e-13 75.9 COG1783@1|root,COG1783@2|Bacteria,1TRQP@1239|Firmicutes,4HDMY@91061|Bacilli,27HA6@186828|Carnobacteriaceae 91061|Bacilli S Terminase RNAseH like domain yqaT - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C k59_601782_1 1234888.K0A2J2_9VIRU 3.99e-59 202.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_521869_1 1692249.A0A0K1RLN8_9CIRC 9.89e-22 95.1 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_337128_3 1005048.CFU_3238 8.23e-05 44.7 COG2944@1|root,COG2944@2|Bacteria,1PT1U@1224|Proteobacteria,2WAKV@28216|Betaproteobacteria,478BI@75682|Oxalobacteraceae 28216|Betaproteobacteria K Helix-turn-helix XRE-family like proteins - - - ko:K07726 - - - - ko00000,ko03000 - - - HTH_3 k59_628198_1 1788452.A0A190WHG0_9CIRC 5.66e-25 105.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_381706_1 1051675.G0YQH9_9CAUD 6.68e-11 62.4 4QE9C@10239|Viruses,4QYNI@35237|dsDNA viruses no RNA stage,4QRG0@28883|Caudovirales,4QP0M@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_550076_1 1122214.AQWH01000025_gene4965 1.2e-09 63.9 COG5281@1|root,COG5281@2|Bacteria,1R47M@1224|Proteobacteria,2TUIV@28211|Alphaproteobacteria,2PJW4@255475|Aurantimonadaceae 28211|Alphaproteobacteria S COG5281, Phage-related minor tail protein - - - - - - - - - - - - - k59_259797_1 382638.Hac_0856 7.29e-12 65.5 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MKR@68525|delta/epsilon subdivisions,2YN1A@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria E Aminotransferase aspB - 2.6.1.1 ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k59_259797_2 797515.HMPREF9103_02905 3.04e-89 280.0 COG1892@1|root,COG1892@2|Bacteria,1V0S3@1239|Firmicutes,4HUB7@91061|Bacilli,3F5P7@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle ppcA - 4.1.1.31 ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00168,M00170,M00171,M00172,M00173,M00346,M00374 R00345 RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPcase_2 k59_136904_1 999411.HMPREF1092_00982 1.7e-50 181.0 COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia,36EV7@31979|Clostridiaceae 186801|Clostridia L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge k59_489323_1 1172188.KB911820_gene2842 7.14e-139 410.0 28MN1@1|root,2ZAXN@2|Bacteria,2H2TF@201174|Actinobacteria 201174|Actinobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6C k59_178557_1 145579.CAPSD_BPPHM 3.46e-22 99.4 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_423118_2 1408226.T233_01724 1.28e-38 157.0 COG3579@1|root,COG3579@2|Bacteria,1TRJN@1239|Firmicutes,4HBZ9@91061|Bacilli,4B0DP@81852|Enterococcaceae 91061|Bacilli E Peptidase C1-like family pepC GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006508,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0009056,GO:0009063,GO:0009636,GO:0009987,GO:0016054,GO:0016787,GO:0019538,GO:0019752,GO:0042221,GO:0043170,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0050667,GO:0050896,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.4.22.40 ko:K01372 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C1_2 k59_607413_2 2003327.CAPSD_BPCHP 1.56e-24 110.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_246433_1 1692244.A0A0K1RLR5_9CIRC 2.31e-57 187.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_205223_2 172088.AUGA01000082_gene6217 5.25e-40 146.0 COG3740@1|root,COG3740@2|Bacteria,1NBQ9@1224|Proteobacteria,2UK6T@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Caudovirus prohead serine protease - - - - - - - - - - - - Peptidase_S78 k59_615538_1 1150991.H9NBX2_9CAUD 2.12e-49 163.0 4QCZV@10239|Viruses,4QYBC@35237|dsDNA viruses no RNA stage,4QSBC@28883|Caudovirales,4QJBJ@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_594963_1 1434319.W5RV19_9CAUD 5.19e-30 119.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_472097_1 1618247.A0A0C5I2K0_9CIRC 3.16e-10 62.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_431111_1 663278.Ethha_1817 3.47e-15 81.6 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,2487V@186801|Clostridia,3WHUH@541000|Ruminococcaceae 186801|Clostridia L Psort location Cytoplasmic, score - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_636425_1 10704.B4UTP0_BP163 7.4e-87 281.0 4QBV3@10239|Viruses,4QW0W@35237|dsDNA viruses no RNA stage,4QPPJ@28883|Caudovirales,4QKW5@10699|Siphoviridae 10699|Siphoviridae S Phage Terminase - - - - - - - - - - - - - k59_636425_2 1038860.AXAP01000015_gene2003 4.32e-98 327.0 COG3740@1|root,COG3740@2|Bacteria,1QVIJ@1224|Proteobacteria,2TVIM@28211|Alphaproteobacteria,3K0XM@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Caudovirus prohead serine protease - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_636425_4 1038860.AXAP01000015_gene2006 8.01e-92 291.0 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,2U6BJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S TIGRFAM phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_61943_2 1692252.A0A0K1RL35_9CIRC 1.29e-95 291.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_144106_1 691965.D4P7I3_9CAUD 5.93e-281 814.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_595262_1 1096546.WYO_0164 1.05e-93 304.0 COG0749@1|root,COG0749@2|Bacteria,1MWX7@1224|Proteobacteria 1224|Proteobacteria L COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A,DNA_pol_A_exo1 k59_533804_1 1121342.AUCO01000012_gene1652 7.92e-11 61.6 2E5K5@1|root,330BC@2|Bacteria,1VC9N@1239|Firmicutes,24MU7@186801|Clostridia,36K12@31979|Clostridiaceae 186801|Clostridia S Siphovirus Gp157 - - - - - - - - - - - - Sipho_Gp157 k59_533804_2 1273125.Rrhod_0983 4.98e-58 189.0 29M5Z@1|root,3083E@2|Bacteria,2IKVT@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_513480_1 926559.JoomaDRAFT_1089 3.11e-46 165.0 COG3378@1|root,COG3378@2|Bacteria,4PP9A@976|Bacteroidetes,1IKGT@117743|Flavobacteriia 976|Bacteroidetes S Phage plasmid primase P4 family - - - - - - - - - - - - VirE_N k59_226210_3 1618241.A0A0C5I2I4_9CIRC 2e-127 374.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_451844_1 2003327.CAPSD_BPCHP 1.66e-72 246.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_61955_2 437329.A5A3R7_9CAUD 2.23e-34 131.0 4QFYS@10239|Viruses,4QYA8@35237|dsDNA viruses no RNA stage,4QUD0@28883|Caudovirales,4QMR9@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_144109_5 396034.A6XMH8_9CAUD 1.18e-44 155.0 4QCB0@10239|Viruses,4QX81@35237|dsDNA viruses no RNA stage,4QPFH@28883|Caudovirales 28883|Caudovirales S YqaJ-like viral recombinase domain - - - - - - - - - - - - - k59_44355_1 401526.TcarDRAFT_1293 4.43e-07 57.0 COG0503@1|root,COG0741@1|root,COG0503@2|Bacteria,COG0741@2|Bacteria,1TSYQ@1239|Firmicutes,4H5A6@909932|Negativicutes 909932|Negativicutes F protein secretion by the type IV secretion system - - - - - - - - - - - - SLT k59_393541_3 1123508.JH636439_gene1604 7.02e-13 71.2 29XN2@1|root,30JDF@2|Bacteria,2J498@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - k59_352068_1 1074488.AGBX01000001_gene429 2.55e-42 162.0 COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,4FBGZ@85020|Dermabacteraceae 201174|Actinobacteria M Transglycosylase pon1 - - - - - - - - - - - PASTA,Transgly,Transpeptidase k59_65474_1 91604.ID47_02960 4.16e-06 53.9 28HS3@1|root,2Z7ZE@2|Bacteria,1QH9A@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_4449_1 1116482.K9L5J1_9CAUD 2.65e-16 78.6 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales 28883|Caudovirales S HNH endonuclease - - - - - - - - - - - - - k59_578209_1 1234888.K0A2J2_9VIRU 2.29e-90 283.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_538331_1 1051675.G0YQG3_9CAUD 6.46e-55 184.0 4QEG2@10239|Viruses,4QVSD@35237|dsDNA viruses no RNA stage,4QRJ9@28883|Caudovirales,4QP0R@10744|Podoviridae 10744|Podoviridae S exonuclease activity - - - - - - - - - - - - - k59_86747_1 1618257.A0A0C5IBI9_9CIRC 6.95e-68 217.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_86747_2 1692249.A0A0K1RLN8_9CIRC 6.85e-71 223.0 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_86747_3 1618248.A0A0C5IB82_9CIRC 4.5e-07 52.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_619671_1 1692255.A0A0K1RL52_9CIRC 1.07e-44 154.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_352077_1 1266925.JHVX01000010_gene1355 9.47e-11 63.9 2DSKH@1|root,33GHY@2|Bacteria,1NI12@1224|Proteobacteria,2WE31@28216|Betaproteobacteria,374B0@32003|Nitrosomonadales 28216|Betaproteobacteria S PEP-CTERM motif - - - - - - - - - - - - VPEP k59_538345_2 316274.Haur_4955 1e-06 55.1 COG4675@1|root,COG4675@2|Bacteria 2|Bacteria M tail collar domain protein - - - - - - - - - - - - Collar k59_168150_6 575540.Isop_2425 2.56e-54 203.0 COG5283@1|root,COG5283@2|Bacteria,2J1F5@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - k59_477734_3 186617.M9M8L2_9VIRU 9.55e-53 192.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_538931_1 1618260.A0A0C5I2C5_9CIRC 4.67e-29 110.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_232895_1 1618238.A0A0C5I2G8_9CIRC 5.22e-38 142.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_232895_2 1379712.S5TMV9_9CIRC 6.3e-09 64.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_338201_2 652103.Rpdx1_3859 5.03e-33 119.0 COG0720@1|root,COG0720@2|Bacteria,1RI4P@1224|Proteobacteria,2VG5E@28211|Alphaproteobacteria,3JZWG@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H PFAM 6-pyruvoyl tetrahydropterin synthase queD - 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 - - - PTPS k59_338201_3 76114.ebA7273 5.4e-112 328.0 28J67@1|root,2Z91Y@2|Bacteria,1R7RG@1224|Proteobacteria,2VRTM@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_523160_1 1144305.PMI02_03196 1.68e-13 75.1 COG4695@1|root,COG4695@2|Bacteria,1MUP5@1224|Proteobacteria,2TT33@28211|Alphaproteobacteria,2K2QM@204457|Sphingomonadales 204457|Sphingomonadales S Phage portal protein - - - - - - - - - - - - Phage_portal k59_543325_2 160492.XF_1560 9.7e-13 74.3 COG3756@1|root,COG3756@2|Bacteria,1N7P7@1224|Proteobacteria,1SDRK@1236|Gammaproteobacteria,1X8A7@135614|Xanthomonadales 135614|Xanthomonadales S ORF located using Glimmer RBSfinder - - - - - - - - - - - - DUF1376 k59_274322_1 417280.A1YZY2_9CAUD 8.33e-107 343.0 4QCZC@10239|Viruses,4QX3V@35237|dsDNA viruses no RNA stage,4QRH3@28883|Caudovirales,4QHVR@10662|Myoviridae 10662|Myoviridae S Bacterial DNA polymerase III alpha subunit - - - - - - - - - - - - - k59_646716_2 706587.Desti_0995 2.28e-09 64.7 COG0358@1|root,COG3378@1|root,COG0358@2|Bacteria,COG3378@2|Bacteria,1MV7I@1224|Proteobacteria,42QE4@68525|delta/epsilon subdivisions,2WM1X@28221|Deltaproteobacteria 28221|Deltaproteobacteria L Phage plasmid primase, P4 family - - - ko:K06919 - - - - ko00000 - - - D5_N,Pox_D5,Toprim_2,zf-CHC2 k59_192780_1 994573.T472_0210770 1.95e-15 81.3 COG4695@1|root,COG4695@2|Bacteria,1TP8B@1239|Firmicutes,2497C@186801|Clostridia,36H1A@31979|Clostridiaceae 186801|Clostridia S Phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_28737_1 1038869.AXAN01000076_gene2993 1.13e-52 169.0 COG0720@1|root,COG0720@2|Bacteria 2|Bacteria H synthase queD - 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 - - - PTPS k59_544059_1 1788454.A0A190WHE4_9CIRC 2.7e-57 189.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_523954_1 742740.HMPREF9474_02273 8.87e-10 63.9 2EAAT@1|root,334F2@2|Bacteria,1VJJI@1239|Firmicutes,24TQU@186801|Clostridia,223KD@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_544065_1 563192.HMPREF0179_02963 2.79e-07 59.7 COG1196@1|root,COG3941@1|root,COG1196@2|Bacteria,COG3941@2|Bacteria 2|Bacteria O tape measure - - - ko:K03529 - - - - ko00000,ko03036 - - - PhageMin_Tail,Tape_meas_lam_C k59_255202_2 1235792.C808_05080 0.000104 48.9 COG0457@1|root,COG0463@1|root,COG0457@2|Bacteria,COG0463@2|Bacteria,1TSF5@1239|Firmicutes,25B5G@186801|Clostridia,27NEB@186928|unclassified Lachnospiraceae 186801|Clostridia M Glycosyl transferase family 2 - - - ko:K00786 - - - - ko00000,ko01000 - - - Glycos_transf_2,TPR_2,TPR_7,TPR_8 k59_647521_1 278957.ABEA03000173_gene2437 4.82e-25 107.0 28HHC@1|root,2Z7T2@2|Bacteria,46VSN@74201|Verrucomicrobia 74201|Verrucomicrobia S AAA domain - - - - - - - - - - - - AAA_24 k59_523983_1 1283300.ATXB01000001_gene707 1.85e-69 235.0 COG4643@1|root,COG5519@1|root,COG4643@2|Bacteria,COG5519@2|Bacteria,1MW5H@1224|Proteobacteria,1RQ7H@1236|Gammaproteobacteria,1XGJ9@135618|Methylococcales 1236|Gammaproteobacteria L Domain of unknown function (DUF927) Z012_01240 - - ko:K06919 - - - - ko00000 - - - DUF927,Prim_Zn_Ribbon,Toprim_3 k59_315038_1 1234888.K0A2J2_9VIRU 4.17e-54 185.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_490371_1 357804.Ping_0145 5.03e-16 87.0 COG1061@1|root,COG1061@2|Bacteria,1N52C@1224|Proteobacteria,1RSQN@1236|Gammaproteobacteria,2QJ0D@267894|Psychromonadaceae 1236|Gammaproteobacteria L Helicase conserved C-terminal domain - - - - - - - - - - - - Helicase_C,ResIII k59_629565_1 313598.MED152_07970 4.64e-13 75.1 COG1361@1|root,COG1470@1|root,COG1361@2|Bacteria,COG1470@2|Bacteria,4NMB8@976|Bacteroidetes,1I0EW@117743|Flavobacteriia 976|Bacteroidetes M Domain of unknown function DUF11 - - - - - - - - - - - - CHU_C,DUF11,He_PIG k59_587742_1 1609634.A0A0C5AFV4_9VIRU 1.6e-14 79.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_215875_1 292459.STH166 5.06e-07 55.5 COG1403@1|root,COG1403@2|Bacteria 2|Bacteria V endonuclease activity - - - - - - - - - - - - HNH,HNH_5 k59_360016_2 1618260.A0A0C5I2C5_9CIRC 9.78e-71 227.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_14509_1 1986029.Q9MBM8_9VIRU 3.13e-36 135.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_14509_2 105154.Q9MBU3_9VIRU 2.97e-08 58.5 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_402850_1 1234888.K0A2J2_9VIRU 9.89e-56 192.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_654964_4 1122622.ATWJ01000008_gene2692 0.000407 45.1 2C4MW@1|root,32RKK@2|Bacteria,2IQ6A@201174|Actinobacteria,4FHDI@85021|Intrasporangiaceae 201174|Actinobacteria S Lsr2 lsr - - - - - - - - - - - Lsr2 k59_466088_1 1298860.AUEM01000009_gene2301 3.24e-24 106.0 COG5479@1|root,COG5479@2|Bacteria,2HYIN@201174|Actinobacteria,4FMC4@85023|Microbacteriaceae 201174|Actinobacteria M hydrolase, family 25 wcqK - - - - - - - - - - - CW_binding_2,LGFP,SH3_3 k59_99659_1 644968.DFW101_3507 4.71e-29 114.0 COG3740@1|root,COG3740@2|Bacteria,1NBQ9@1224|Proteobacteria,431K2@68525|delta/epsilon subdivisions,2WX1Z@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Caudovirus prohead serine protease - - - - - - - - - - - - Peptidase_S78 k59_300916_1 1123312.KB904575_gene72 1.15e-19 90.1 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4H9YP@91061|Bacilli 91061|Bacilli L SNF2 family - - - - - - - - - - - - Helicase_C,SNF2_N k59_320870_1 182851.I4AZE0_9CAUD 4.73e-14 81.3 4QDXC@10239|Viruses,4QX56@35237|dsDNA viruses no RNA stage,4QPBP@28883|Caudovirales,4QM67@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_100480_1 351016.RAZWK3B_16615 4.55e-70 254.0 2FFRP@1|root,347NW@2|Bacteria,1P2BR@1224|Proteobacteria,2UVQC@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_630247_1 584708.Apau_0467 3.18e-05 50.8 COG3108@1|root,COG3108@2|Bacteria,3TBND@508458|Synergistetes 508458|Synergistetes S Peptidase M15 - - - - - - - - - - - - Peptidase_M15_3 k59_320878_1 1234888.K0A2J2_9VIRU 2.53e-77 249.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_34177_2 1121100.JCM6294_535 2.62e-98 306.0 COG0553@1|root,COG0863@1|root,COG0553@2|Bacteria,COG0863@2|Bacteria,4NHHF@976|Bacteroidetes,2FRI5@200643|Bacteroidia,4ATW7@815|Bacteroidaceae 976|Bacteroidetes KL DNA methylase - - - - - - - - - - - - Helicase_C,N6_N4_Mtase,SNF2_N k59_285227_1 1262449.CP6013_2050 0.000716 51.6 COG1061@1|root,COG1061@2|Bacteria,1UU4V@1239|Firmicutes,259QZ@186801|Clostridia,36F41@31979|Clostridiaceae 186801|Clostridia L DEAD-like helicases superfamily - - - - - - - - - - - - Helicase_C,ResIII k59_408984_1 1220534.B655_1301 0.00043 51.2 COG0417@1|root,arCOG00328@2157|Archaea,2XU1K@28890|Euryarchaeota,23NV0@183925|Methanobacteria 183925|Methanobacteria L DNA polymerase, family B, exonuclease domain polB1 - 2.7.7.7 ko:K02319 ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032 - - - DNA_pol_B,DNA_pol_B_exo1 k59_57600_1 762982.HMPREF9442_01170 6.03e-27 110.0 COG1475@1|root,COG1475@2|Bacteria,4P1X3@976|Bacteroidetes,2FRXC@200643|Bacteroidia 976|Bacteroidetes K Psort location Cytoplasmic, score 8.96 - - - - - - - - - - - - DUF4417,ParBc k59_244058_1 1392498.JQLH01000001_gene3554 7.5e-07 53.1 COG3291@1|root,COG4412@1|root,COG5184@1|root,COG3291@2|Bacteria,COG4412@2|Bacteria,COG5184@2|Bacteria,4P2UU@976|Bacteroidetes,1HYAX@117743|Flavobacteriia,2PI55@252356|Maribacter 976|Bacteroidetes DZ Mycoplasma protein of unknown function, DUF285 - - - - - - - - - - - - CHU_C,Cadherin,DUF285,TIG,TSP_3 k59_118815_1 1692242.A0A0K1RL37_9CIRC 3.91e-63 208.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_327003_1 457424.BFAG_01448 2e-32 128.0 COG3740@1|root,COG3740@2|Bacteria,4NDXV@976|Bacteroidetes,2FQ9I@200643|Bacteroidia,4APPV@815|Bacteroidaceae 976|Bacteroidetes S Phage prohead protease, HK97 family - - - - - - - - - - - - - k59_285260_1 1382304.JNIL01000001_gene3514 4.06e-26 122.0 COG3378@1|root,COG3378@2|Bacteria,1TQP9@1239|Firmicutes,4HBTB@91061|Bacilli 91061|Bacilli L Phage plasmid primase, P4 - - - ko:K06919 - - - - ko00000 - - - D5_N,Pox_D5,RepB_primase,Toprim_4,zf-CHC2 k59_512250_3 380358.XALC_0203 5.62e-113 346.0 COG0270@1|root,COG0270@2|Bacteria,1MV9H@1224|Proteobacteria,1RPSH@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase,Dam,MethyltransfD12 k59_162756_1 1379281.AVAG01000078_gene1575 2.85e-07 58.5 COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2WJR3@28221|Deltaproteobacteria,2M9BW@213115|Desulfovibrionales 28221|Deltaproteobacteria L PFAM UvrD REP helicase pcrA - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k59_81983_1 877455.Metbo_2475 4.27e-15 82.4 COG3291@1|root,arCOG02516@1|root,arCOG09475@1|root,arCOG02508@2157|Archaea,arCOG02510@2157|Archaea,arCOG02516@2157|Archaea,arCOG09475@2157|Archaea,2Y7U0@28890|Euryarchaeota 28890|Euryarchaeota S Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - - - - - - - - - - PKD k59_119950_1 1472912.A0A023NGU4_9CAUD 1.51e-14 79.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales 28883|Caudovirales S N-acetylmuramoyl-L-alanine amidase activity - GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019058,GO:0019062,GO:0022610,GO:0039638,GO:0044403,GO:0044406,GO:0044419,GO:0044423,GO:0044650,GO:0051704,GO:0098015,GO:0098024 - - - - - - - - - - - k59_286554_2 186617.M9M8L2_9VIRU 1.15e-44 160.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_327959_7 864069.MicloDRAFT_00032110 8.13e-05 46.2 2DSGM@1|root,33G20@2|Bacteria,1NM38@1224|Proteobacteria,2UW9B@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_58778_1 1234888.K0A2J2_9VIRU 1.78e-71 234.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_512353_1 1041147.AUFB01000014_gene329 1.64e-17 84.3 2CXZV@1|root,32T32@2|Bacteria,1N4R9@1224|Proteobacteria,2UM96@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_58781_2 33876.JNXY01000014_gene3951 0.000119 48.5 COG4972@1|root,COG4972@2|Bacteria,2IBNF@201174|Actinobacteria,4DAHI@85008|Micromonosporales 201174|Actinobacteria NU Type IV pilus assembly protein PilM; pilM - - ko:K02662 - - - - ko00000,ko02035,ko02044 - - - PilM_2 k59_366589_1 1329250.WOSG25_220160 0.00068 49.3 COG4695@1|root,COG4695@2|Bacteria,1TP8B@1239|Firmicutes,4HHWD@91061|Bacilli,4AWY2@81850|Leuconostocaceae 91061|Bacilli S Phage portal protein - - - - - - - - - - - - Phage_portal k59_286695_1 1126411.I1TEL3_9CIRC 2.22e-38 138.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_286695_3 1234880.K0A2H8_9CIRC 2.88e-42 149.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_162875_1 1234888.K0A2J2_9VIRU 6.45e-40 147.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_166182_1 753085.F4YCV3_9CAUD 2.55e-72 239.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_166182_2 411473.RUMCAL_00274 4.48e-144 426.0 COG0553@1|root,COG0553@2|Bacteria,1TP2C@1239|Firmicutes,24DVA@186801|Clostridia,3WP9W@541000|Ruminococcaceae 186801|Clostridia KL DEAD-like helicases superfamily - - - - - - - - - - - - Helicase_C,N6_N4_Mtase,SNF2_N k59_494323_2 1210908.HSB1_10570 8.82e-08 59.7 COG0500@1|root,arCOG01402@2157|Archaea,2XYWP@28890|Euryarchaeota,23WPJ@183963|Halobacteria 183963|Halobacteria Q COG0500 SAM-dependent methyltransferases - - - - - - - - - - - - Methyltransf_21 k59_494323_3 1232446.BAIE02000007_gene1995 5.61e-06 52.8 COG0500@1|root,COG2226@2|Bacteria,1TQEA@1239|Firmicutes,24HII@186801|Clostridia 186801|Clostridia Q Methyltransferase - - - - - - - - - - - - Methyltransf_11,Methyltransf_25,Methyltransf_31 k59_104215_2 886377.Murru_1897 1.48e-07 60.5 COG1361@1|root,COG2911@1|root,COG1361@2|Bacteria,COG2911@2|Bacteria,4NG16@976|Bacteroidetes,1HY10@117743|Flavobacteriia 976|Bacteroidetes M C-terminal domain of CHU protein family - - - - - - - - - - - - CHU_C,Calx-beta,DUF11,SdrD_B k59_412277_1 1380350.JIAP01000026_gene3419 1.52e-16 86.7 COG4678@1|root,COG4678@2|Bacteria,1N4B4@1224|Proteobacteria,2UE3B@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Muramidase (Phage lambda lysozyme) - - - - - - - - - - - - - k59_412277_2 1057002.KB905370_gene5880 1.97e-13 75.1 2C22H@1|root,305QB@2|Bacteria,1RFAD@1224|Proteobacteria,2U8GY@28211|Alphaproteobacteria,4BEFE@82115|Rhizobiaceae 28211|Alphaproteobacteria S Chaperone of endosialidase - - - - - - - - - - - - Peptidase_S74 k59_535727_1 1111479.AXAR01000022_gene1061 4.99e-06 51.6 COG1396@1|root,COG1396@2|Bacteria 2|Bacteria K sequence-specific DNA binding - - - - - - - - - - - - HTH_19,HTH_3 k59_350589_1 1029824.AFID01000010_gene1132 0.000124 51.2 COG0739@1|root,COG0739@2|Bacteria,2GKXN@201174|Actinobacteria,1W8U4@1268|Micrococcaceae 201174|Actinobacteria M Peptidase family M23 - - - - - - - - - - - - Peptidase_M23 k59_494327_1 1227261.HMPREF0043_01904 3.01e-39 145.0 COG0842@1|root,COG0842@2|Bacteria,2IB08@201174|Actinobacteria,4D4NV@85005|Actinomycetales 201174|Actinobacteria V ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane,ABC2_membrane_3 k59_494327_2 1435356.Y013_00245 0.000168 45.1 COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4FVC9@85025|Nocardiaceae 201174|Actinobacteria V AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 k59_535729_2 523850.TON_1368 4.96e-15 75.1 COG2131@1|root,arCOG01487@2157|Archaea,2XXBC@28890|Euryarchaeota,24304@183968|Thermococci 183968|Thermococci F MafB19-like deaminase - - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 k59_638440_1 1177928.TH2_05253 3.01e-29 131.0 COG1511@1|root,COG3941@1|root,COG1511@2|Bacteria,COG3941@2|Bacteria 2|Bacteria O tape measure - - - - - - - - - - - - DUF4175,TMP_2,Tape_meas_lam_C k59_596667_1 1122225.AULQ01000001_gene1526 3.72e-06 55.5 COG1345@1|root,COG1361@1|root,COG1404@1|root,COG3227@1|root,COG3897@1|root,COG1345@2|Bacteria,COG1361@2|Bacteria,COG1404@2|Bacteria,COG3227@2|Bacteria,COG3897@2|Bacteria 2|Bacteria P peptidase activity, acting on L-amino acid peptides - - - - - - - - - - - - DUF1573,Laminin_G_3,MAM,Peptidase_M8,SLH k59_432706_1 29176.XP_003882813.1 0.00012 53.5 COG0749@1|root,KOG2373@1|root,KOG0950@2759|Eukaryota,KOG2373@2759|Eukaryota,3YHT2@5794|Apicomplexa,3YKT6@5796|Coccidia,3YUR3@5809|Sarcocystidae 5794|Apicomplexa L Toprim-like - - 2.7.7.7,3.6.4.12 ko:K02335,ko:K17680 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03029,ko03032,ko03400 - - - AAA_25,DNA_pol_A,DNA_pol_A_exo1,Toprim_2 k59_84437_1 548479.HMPREF0573_11065 2.72e-15 80.5 COG5184@1|root,COG5184@2|Bacteria,2IG31@201174|Actinobacteria,4D6TS@85005|Actinomycetales 201174|Actinobacteria DZ Regulator of chromosome condensation (RCC1) repeat - - - - - - - - - - - - CW_binding_2,RCC1,RCC1_2 k59_186890_1 634452.APA01_44190 2.89e-24 100.0 28S8J@1|root,2ZEJW@2|Bacteria,1P7FP@1224|Proteobacteria,2UWWA@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - HTH_Crp_2 k59_556059_1 1379709.S5TMV0_9CIRC 2.48e-28 113.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_494689_1 2003327.CAPSD_BPCHP 4.9e-34 133.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_248983_3 1385658.U5KPZ6_9VIRU 3.46e-96 301.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_536146_1 1341151.ASZU01000008_gene1531 1.96e-53 186.0 COG1783@1|root,COG1783@2|Bacteria,1VK0H@1239|Firmicutes,4HQ2H@91061|Bacilli 91061|Bacilli S Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C k59_599709_1 864702.OsccyDRAFT_0687 2.94e-51 171.0 2CWXD@1|root,32T0J@2|Bacteria,1GAQJ@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - k59_539961_1 1609634.A0A0C5AFV4_9VIRU 5.49e-54 186.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_497796_1 591158.SSMG_02404 3.84e-24 102.0 COG0741@1|root,COG0741@2|Bacteria,2IGMV@201174|Actinobacteria 201174|Actinobacteria M Transglycosylase SLT domain - - - - - - - - - - - - PG_binding_1,SLT,T7SS_ESX_EspC k59_189962_1 1234888.K0A2J2_9VIRU 1.32e-52 182.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_312220_2 525368.HMPREF0591_0544 4.85e-39 140.0 COG0582@1|root,COG0582@2|Bacteria,2I2P9@201174|Actinobacteria,238VB@1762|Mycobacteriaceae 201174|Actinobacteria L to the 'phage' integrase family - - - - - - - - - - - - Phage_int_SAM_1,Phage_integrase k59_128662_1 479431.Namu_4628 1.13e-35 131.0 COG4725@1|root,COG4725@2|Bacteria,2IIR3@201174|Actinobacteria,4EVXR@85013|Frankiales 201174|Actinobacteria KT Belongs to the MT-A70-like family - - - - - - - - - - - - MT-A70 k59_292663_1 1204521.I6ZXZ4_9CAUD 1.36e-43 157.0 4QHBE@10239|Viruses,4QT2W@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_292663_3 911008.GLAD_01282 4.11e-31 124.0 28H9R@1|root,2Z7MD@2|Bacteria,1MVTR@1224|Proteobacteria,1RMPH@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Psort location Cytoplasmic, score 8.96 yfjQ - - - - - - - - - - - DUF932 k59_394682_1 941970.E7DUK7_9CAUD 2.91e-08 62.0 4QCM9@10239|Viruses,4QVZV@35237|dsDNA viruses no RNA stage,4QTYN@28883|Caudovirales,4QP2Y@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_251865_2 1692242.A0A0K1RKZ2_9CIRC 1.79e-16 82.4 4QFEW@10239|Viruses,4QUKZ@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_152017_1 1298867.AUES01000008_gene5183 1.23e-36 145.0 COG0358@1|root,COG0749@1|root,COG4643@1|root,COG0358@2|Bacteria,COG0749@2|Bacteria,COG4643@2|Bacteria,1MW9E@1224|Proteobacteria,2TS3B@28211|Alphaproteobacteria,3K18F@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Toprim domain - - - ko:K06919 - - - - ko00000 - - - Toprim_3 k59_255332_1 1122605.KB893643_gene665 8.88e-59 208.0 COG3378@1|root,COG3378@2|Bacteria,4NNKX@976|Bacteroidetes,1ISH6@117747|Sphingobacteriia 976|Bacteroidetes L Bifunctional DNA primase/polymerase, N-terminal - - - - - - - - - - - - Prim-Pol k59_255332_2 985255.APHJ01000018_gene3098 1.07e-84 272.0 COG3378@1|root,COG3378@2|Bacteria,4PP9A@976|Bacteroidetes,1IKGT@117743|Flavobacteriia 976|Bacteroidetes S Phage plasmid primase P4 family - - - - - - - - - - - - VirE_N k59_9652_2 1234888.K0A2J2_9VIRU 3.67e-88 279.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_624676_1 1101195.Meth11DRAFT_1274 2.04e-05 50.8 2F07U@1|root,33TBB@2|Bacteria,1NRBT@1224|Proteobacteria,2W10R@28216|Betaproteobacteria,2KNPB@206350|Nitrosomonadales 206350|Nitrosomonadales - - - - - - - - - - - - - - - k59_544256_2 665571.STHERM_c17410 9.91e-13 68.2 COG4696@1|root,COG4696@2|Bacteria 2|Bacteria J Protein conserved in bacteria XK27_03185 - - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - Acetyltransf_3,Hydrolase_3,PRA-PH k59_152018_1 691965.D4P7I3_9CAUD 2.57e-160 488.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_109202_1 1692256.A0A0K1RL85_9CIRC 4.68e-57 185.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_109202_3 1692256.A0A0K1RL85_9CIRC 1.01e-98 295.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_315631_1 441620.Mpop_0342 2.07e-05 50.8 COG0582@1|root,COG0582@2|Bacteria,1MXNK@1224|Proteobacteria,2TUAT@28211|Alphaproteobacteria,1JUH1@119045|Methylobacteriaceae 28211|Alphaproteobacteria L Phage integrase family - - - - - - - - - - - - Phage_integrase k59_544698_6 42256.RradSPS_0202 2.87e-27 125.0 COG0749@1|root,COG0749@2|Bacteria,2GJY2@201174|Actinobacteria,4CP7C@84995|Rubrobacteria 84995|Rubrobacteria L DNA polymerase - - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - DNA_pol_A,DNA_pol_A_exo1 k59_93097_1 294631.Q5ZGC6_9CAUD 9.22e-81 253.0 4QAIK@10239|Viruses,4QUPH@35237|dsDNA viruses no RNA stage,4QPEB@28883|Caudovirales,4QKNC@10699|Siphoviridae 10699|Siphoviridae S hydrolase activity - - - - - - - - - - - - - k59_70687_1 445961.IW15_16110 7.15e-48 172.0 COG0582@1|root,COG0582@2|Bacteria,4NDZJ@976|Bacteroidetes,1HZ88@117743|Flavobacteriia,3ZPXX@59732|Chryseobacterium 976|Bacteroidetes L Phage integrase SAM-like domain - - - - - - - - - - - - Phage_int_SAM_5,Phage_integrase k59_9953_1 1454004.AW11_00641 0.000959 45.8 COG2204@1|root,COG5001@1|root,COG2204@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria 28216|Betaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_4,PAS_9,Response_reg k59_504944_1 1280689.AUJC01000003_gene963 1.61e-47 172.0 2DB9U@1|root,2Z7Z6@2|Bacteria,1TR67@1239|Firmicutes,249U6@186801|Clostridia,36FNK@31979|Clostridiaceae 186801|Clostridia S Phage portal protein, SPP1 Gp6-like - - - - - - - - - - - - Phage_prot_Gp6 k59_33128_12 33035.JPJF01000033_gene2261 2.56e-10 70.9 COG4675@1|root,COG4675@2|Bacteria,1UI0V@1239|Firmicutes,25E9P@186801|Clostridia 186801|Clostridia S tail collar domain protein - - - - - - - - - - - - - k59_550526_2 399739.Pmen_0185 5.29e-08 59.7 COG0739@1|root,COG0739@2|Bacteria,1RIS0@1224|Proteobacteria,1S6KP@1236|Gammaproteobacteria,1YD3S@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria M Peptidase family M23 - - - - - - - - - - - - DUF4124,Peptidase_M23 k59_654360_1 762948.HMPREF0733_10457 2.26e-87 265.0 COG1054@1|root,COG1054@2|Bacteria,2GMMP@201174|Actinobacteria,1W8JF@1268|Micrococcaceae 201174|Actinobacteria S Belongs to the UPF0176 family - - - ko:K07146 - - - - ko00000 - - - Rhodanese,Rhodanese_C k59_654369_1 411477.PARMER_00988 1.81e-52 175.0 COG1533@1|root,COG1533@2|Bacteria,4P2UW@976|Bacteroidetes,2FS17@200643|Bacteroidia,23047@171551|Porphyromonadaceae 976|Bacteroidetes L DNA photolyase activity - - - - - - - - - - - - - k59_550571_1 1234888.K0A2J2_9VIRU 9.28e-59 197.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_279172_1 742767.HMPREF9456_03368 2.58e-09 68.6 COG5280@1|root,COG5280@2|Bacteria,4PNYN@976|Bacteroidetes,2FPMT@200643|Bacteroidia 976|Bacteroidetes S domain protein - - - - - - - - - - - - - k59_51603_1 398720.MED217_15260 1.96e-11 70.5 COG5295@1|root,COG5295@2|Bacteria,4NJTK@976|Bacteroidetes,1HZNB@117743|Flavobacteriia 976|Bacteroidetes UW surface antigen - - - - - - - - - - - - Peptidase_S74 k59_237705_2 1501230.ET33_26505 1e-26 112.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4H9YP@91061|Bacilli,26W69@186822|Paenibacillaceae 91061|Bacilli L SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,SNF2_N k59_197808_1 1618241.A0A0C5I2I4_9CIRC 9.8e-108 322.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_179619_2 1121866.AUGK01000007_gene323 6.59e-06 50.4 COG2271@1|root,COG2271@2|Bacteria,2H7G8@201174|Actinobacteria,4CXFZ@84998|Coriobacteriia 84998|Coriobacteriia G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 k59_300989_1 11082.PRO_0000037753 3.88e-206 598.0 4QBXT@10239|Viruses,4R138@439488|ssRNA viruses,4R0R1@35278|ssRNA positive-strand viruses no DNA stage 10239|Viruses K ATP-dependent helicase activity - GO:0000122,GO:0001172,GO:0001510,GO:0001558,GO:0001817,GO:0001818,GO:0001932,GO:0001933,GO:0001934,GO:0001959,GO:0001960,GO:0001961,GO:0002039,GO:0002673,GO:0002674,GO:0002682,GO:0002683,GO:0002694,GO:0002695,GO:0002697,GO:0002698,GO:0002791,GO:0002792,GO:0002831,GO:0002832,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003725,GO:0003727,GO:0003824,GO:0003968,GO:0004175,GO:0004252,GO:0004483,GO:0005102,GO:0005124,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005793,GO:0006139,GO:0006355,GO:0006357,GO:0006396,GO:0006417,GO:0006508,GO:0006725,GO:0006807,GO:0006810,GO:0006897,GO:0006898,GO:0007155,GO:0007159,GO:0008104,GO:0008134,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008174,GO:0008233,GO:0008236,GO:0008270,GO:0008284,GO:0008285,GO:0008757,GO:0009058,GO:0009059,GO:0009451,GO:0009452,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010562,GO:0010563,GO:0010564,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0010639,GO:0010646,GO:0010647,GO:0010648,GO:0010692,GO:0010694,GO:0010803,GO:0010804,GO:0010821,GO:0010823,GO:0010921,GO:0010922,GO:0010941,GO:0015031,GO:0015833,GO:0016020,GO:0016032,GO:0016070,GO:0016071,GO:0016192,GO:0016462,GO:0016556,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017016,GO:0017111,GO:0017137,GO:0017151,GO:0017171,GO:0018130,GO:0018995,GO:0019048,GO:0019049,GO:0019050,GO:0019054,GO:0019056,GO:0019058,GO:0019065,GO:0019068,GO:0019080,GO:0019082,GO:0019215,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019538,GO:0019899,GO:0019900,GO:0019902,GO:0019903,GO:0020012,GO:0022610,GO:0023051,GO:0023056,GO:0023057,GO:0030162,GO:0030234,GO:0030260,GO:0030307,GO:0030430,GO:0030682,GO:0030683,GO:0030888,GO:0030889,GO:0031072,GO:0031090,GO:0031267,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031329,GO:0031330,GO:0031347,GO:0031348,GO:0031369,GO:0031399,GO:0031400,GO:0031401,GO:0031952,GO:0031953,GO:0032069,GO:0032074,GO:0032101,GO:0032102,GO:0032259,GO:0032268,GO:0032269,GO:0032270,GO:0032386,GO:0032465,GO:0032467,GO:0032675,GO:0032715,GO:0032774,GO:0032780,GO:0032879,GO:0032880,GO:0032944,GO:0032945,GO:0032991,GO:0032993,GO:0033036,GO:0033043,GO:0033116,GO:0033592,GO:0033643,GO:0033644,GO:0033645,GO:0033646,GO:0033647,GO:0033648,GO:0033650,GO:0033655,GO:0033662,GO:0033663,GO:0033668,GO:0033673,GO:0034062,GO:0034121,GO:0034122,GO:0034135,GO:0034136,GO:0034143,GO:0034144,GO:0034155,GO:0034156,GO:0034163,GO:0034164,GO:0034248,GO:0034250,GO:0034641,GO:0034654,GO:0035303,GO:0035306,GO:0035325,GO:0035663,GO:0035821,GO:0036260,GO:0036265,GO:0039502,GO:0039503,GO:0039506,GO:0039507,GO:0039513,GO:0039516,GO:0039526,GO:0039527,GO:0039547,GO:0039560,GO:0039580,GO:0039584,GO:0039612,GO:0039613,GO:0039644,GO:0039653,GO:0039656,GO:0039657,GO:0039713,GO:0039714,GO:0040008,GO:0042000,GO:0042025,GO:0042127,GO:0042287,GO:0042288,GO:0042325,GO:0042326,GO:0042327,GO:0042509,GO:0042532,GO:0042802,GO:0042886,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043085,GO:0043086,GO:0043122,GO:0043123,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043414,GO:0043462,GO:0043487,GO:0043489,GO:0043549,GO:0043656,GO:0043657,GO:0043900,GO:0043901,GO:0043902,GO:0043903,GO:0044003,GO:0044053,GO:0044068,GO:0044092,GO:0044093,GO:0044164,GO:0044165,GO:0044167,GO:0044177,GO:0044186,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044220,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044279,GO:0044359,GO:0044362,GO:0044403,GO:0044409,GO:0044413,GO:0044414,GO:0044415,GO:0044417,GO:0044419,GO:0044422,GO:0044424,GO:0044444,GO:0044464,GO:0044501,GO:0044531,GO:0044532,GO:0044766,GO:0044833,GO:0044877,GO:0045069,GO:0045070,GO:0045088,GO:0045184,GO:0045727,GO:0045787,GO:0045824,GO:0045862,GO:0045892,GO:0045927,GO:0045934,GO:0045936,GO:0045937,GO:0046425,GO:0046426,GO:0046483,GO:0046718,GO:0046755,GO:0046762,GO:0046774,GO:0046794,GO:0046872,GO:0046914,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048524,GO:0048583,GO:0048584,GO:0048585,GO:0050670,GO:0050672,GO:0050687,GO:0050688,GO:0050689,GO:0050690,GO:0050691,GO:0050708,GO:0050709,GO:0050727,GO:0050728,GO:0050730,GO:0050732,GO:0050776,GO:0050777,GO:0050789,GO:0050790,GO:0050792,GO:0050794,GO:0050864,GO:0050865,GO:0050866,GO:0050869,GO:0050896,GO:0051020,GO:0051046,GO:0051047,GO:0051048,GO:0051049,GO:0051050,GO:0051051,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051223,GO:0051224,GO:0051234,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051248,GO:0051249,GO:0051250,GO:0051252,GO:0051253,GO:0051302,GO:0051336,GO:0051338,GO:0051345,GO:0051346,GO:0051348,GO:0051701,GO:0051704,GO:0051707,GO:0051726,GO:0051781,GO:0051805,GO:0051806,GO:0051807,GO:0051808,GO:0051817,GO:0051828,GO:0051832,GO:0051833,GO:0051834,GO:0051836,GO:0052026,GO:0052027,GO:0052029,GO:0052031,GO:0052037,GO:0052038,GO:0052040,GO:0052041,GO:0052053,GO:0052055,GO:0052056,GO:0052148,GO:0052150,GO:0052167,GO:0052170,GO:0052173,GO:0052199,GO:0052200,GO:0052203,GO:0052204,GO:0052205,GO:0052230,GO:0052248,GO:0052250,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052312,GO:0052433,GO:0052490,GO:0052493,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0060147,GO:0060149,GO:0060255,GO:0060338,GO:0060339,GO:0060341,GO:0060548,GO:0060589,GO:0060590,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0060759,GO:0060760,GO:0060761,GO:0060966,GO:0060967,GO:0060968,GO:0060969,GO:0065007,GO:0065008,GO:0065009,GO:0070011,GO:0070103,GO:0070104,GO:0070201,GO:0070486,GO:0070663,GO:0070664,GO:0071593,GO:0071702,GO:0071704,GO:0071705,GO:0072583,GO:0075109,GO:0075111,GO:0075112,GO:0075114,GO:0075136,GO:0075344,GO:0075509,GO:0075512,GO:0075528,GO:0080009,GO:0080090,GO:0080134,GO:0080135,GO:0090068,GO:0090087,GO:0090199,GO:0090201,GO:0090304,GO:0097159,GO:0097617,GO:0097659,GO:0097677,GO:0097747,GO:0098588,GO:0098609,GO:0098657,GO:0098772,GO:0106005,GO:0140096,GO:0140098,GO:1900101,GO:1900102,GO:1900117,GO:1900118,GO:1900368,GO:1900369,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901576,GO:1902369,GO:1902531,GO:1902532,GO:1902533,GO:1902579,GO:1902679,GO:1903265,GO:1903506,GO:1903507,GO:1903530,GO:1903531,GO:1903573,GO:1903719,GO:1903721,GO:1903900,GO:1903902,GO:1904892,GO:1904893,GO:1904950,GO:1905897,GO:1990214,GO:1990216,GO:1990219,GO:1990254,GO:1990814,GO:1990904,GO:2000112,GO:2000113,GO:2001141,GO:2001233,GO:2001234 - - - - - - - - - - - k59_79953_4 1177928.TH2_05208 5.95e-28 129.0 COG4733@1|root,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria,2TV2W@28211|Alphaproteobacteria,2JV2T@204441|Rhodospirillales 204441|Rhodospirillales S COG4733 Phage-related protein, tail component - - - - - - - - - - - - Lambda_tail_I,Phage-tail_3 k59_612199_1 589924.Ferp_0182 3.96e-33 134.0 COG0582@1|root,arCOG01242@2157|Archaea,2Y83U@28890|Euryarchaeota,246MT@183980|Archaeoglobi 183980|Archaeoglobi L Phage integrase family - - - - - - - - - - - - Phage_integrase k59_325819_1 1254432.SCE1572_30410 8.4e-32 137.0 COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2YUPG@29|Myxococcales 28221|Deltaproteobacteria O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner - - 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C k59_325819_2 7091.BGIBMGA000703-TA 1.75e-08 60.8 KOG1971@1|root,KOG1971@2759|Eukaryota,397ZU@33154|Opisthokonta,3CC8V@33208|Metazoa,3DTIT@33213|Bilateria,429MT@6656|Arthropoda,3SXB0@50557|Insecta,4446V@7088|Lepidoptera 33208|Metazoa O procollagen-lysine 5-dioxygenase activity - - 1.14.11.4 ko:K13647 ko00310,map00310 - R03376 RC00709 ko00000,ko00001,ko01000 - - - - k59_634665_1 10855.H_SPV4 2.56e-05 50.4 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_408322_2 1618248.A0A0C5IB82_9CIRC 1.23e-16 86.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_20248_1 485913.Krac_12128 1.07e-34 133.0 COG0305@1|root,COG0305@2|Bacteria,2G64D@200795|Chloroflexi 200795|Chloroflexi L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_306121_1 572544.Ilyop_1048 3.59e-12 66.6 COG0863@1|root,COG1475@1|root,COG2189@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,COG2189@2|Bacteria,37AID@32066|Fusobacteria 32066|Fusobacteria L DNA methylase - - - - - - - - - - - - N6_N4_Mtase,ParBc k59_306121_2 886379.AEWI01000001_gene1750 1.03e-14 79.3 COG0863@1|root,COG0863@2|Bacteria,4PIKF@976|Bacteroidetes,2G1FK@200643|Bacteroidia,3XM01@558415|Marinilabiliaceae 976|Bacteroidetes L DNA methylase - - - - - - - - - - - - N6_N4_Mtase k59_306139_1 1234888.K0A2J2_9VIRU 2.02e-53 186.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_20326_1 414684.RC1_0053 4.16e-10 67.4 COG4643@1|root,COG5545@1|root,COG4643@2|Bacteria,COG5545@2|Bacteria,1MVGK@1224|Proteobacteria,2U0ID@28211|Alphaproteobacteria,2JVCN@204441|Rhodospirillales 204441|Rhodospirillales S Virulence-associated protein E - - - - - - - - - - - - Toprim_3,VirE k59_572141_4 1204521.I7A8M7_9CAUD 1.2e-30 133.0 4QCZC@10239|Viruses,4QX3V@35237|dsDNA viruses no RNA stage,4QRH3@28883|Caudovirales,4QHVR@10662|Myoviridae 10662|Myoviridae S Bacterial DNA polymerase III alpha subunit - - - - - - - - - - - - - k59_616857_1 991.IW20_16405 1.3e-37 132.0 2BGX2@1|root,32AX0@2|Bacteria,4NY7K@976|Bacteroidetes,1IDC4@117743|Flavobacteriia,2NXZR@237|Flavobacterium 976|Bacteroidetes - - - - - - - - - - - - - - - k59_616857_2 537011.PREVCOP_05775 2.51e-08 58.2 COG1595@1|root,COG1595@2|Bacteria,4NQH8@976|Bacteroidetes,2FT5W@200643|Bacteroidia 976|Bacteroidetes K DNA-templated transcription, initiation - - - - - - - - - - - - - k59_391181_1 195253.Syn6312_2899 2.06e-108 325.0 COG1403@1|root,COG1403@2|Bacteria,1G2XW@1117|Cyanobacteria 1117|Cyanobacteria L HNH endonuclease - - - - - - - - - - - - HNH,HNH_5,RRXRR k59_21953_1 592029.DDD_2206 3.56e-10 68.9 COG0729@1|root,COG5295@1|root,COG0729@2|Bacteria,COG5295@2|Bacteria,4PDJG@976|Bacteroidetes,1IE0P@117743|Flavobacteriia,3HJZH@363408|Nonlabens 976|Bacteroidetes UW Hep Hag repeat protein - - - - - - - - - - - - - k59_329934_1 1788439.A0A190WHD0_9CIRC 5.18e-34 132.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_226738_2 1367847.JCM7686_2906 1.71e-22 99.4 COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,2TSJN@28211|Alphaproteobacteria,2PY3T@265|Paracoccus 28211|Alphaproteobacteria L impB/mucB/samB family C-terminal domain - - 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C k59_62911_1 706587.Desti_2197 3.75e-64 209.0 COG4422@1|root,COG4422@2|Bacteria,1MXQI@1224|Proteobacteria,42WFA@68525|delta/epsilon subdivisions,2X5AZ@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Pfam:Gp37_Gp68 - - - - - - - - - - - - DUF5131 k59_308756_3 1692252.A0A0K1RL35_9CIRC 2.83e-73 231.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_1837_2 485913.Krac_0204 6.28e-14 75.1 COG3864@1|root,COG3864@2|Bacteria 2|Bacteria S Putative metallopeptidase domain - - - - - - - - - - - - DUF2201,DUF2201_N k59_308961_1 487796.Flav2ADRAFT_0708 1.23e-06 56.2 COG2304@1|root,COG2885@1|root,COG3343@1|root,COG5184@1|root,COG5563@1|root,COG2304@2|Bacteria,COG2885@2|Bacteria,COG3343@2|Bacteria,COG5184@2|Bacteria,COG5563@2|Bacteria,4NI94@976|Bacteroidetes,1HZ68@117743|Flavobacteriia 976|Bacteroidetes M COG3210 Large exoproteins involved in heme utilization or adhesion - - - - - - - - - - - - FG-GAP_2 k59_103879_1 1556290.A0A0A0RQH0_9CAUD 8.05e-56 200.0 4QAK6@10239|Viruses,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_596172_1 45406.Q06EI0_BPR32 3.37e-07 58.2 4QB5A@10239|Viruses,4QYU7@35237|dsDNA viruses no RNA stage,4QU2H@28883|Caudovirales,4QJ7N@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_63109_2 1408438.JADD01000004_gene1090 2.7e-05 55.5 COG3378@1|root,COG3378@2|Bacteria,1TQP9@1239|Firmicutes,4HA5U@91061|Bacilli,27DM0@186827|Aerococcaceae 91061|Bacilli S Phage plasmid primase, P4 family - - - ko:K06919 - - - - ko00000 - - - D5_N,Pox_D5 k59_44390_4 1117943.SFHH103_00152 8.85e-43 147.0 COG3023@1|root,COG3023@2|Bacteria,1RM19@1224|Proteobacteria,2UBBX@28211|Alphaproteobacteria,4BFWD@82115|Rhizobiaceae 28211|Alphaproteobacteria V N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - Amidase_2,SH3_3 k59_270589_1 1238184.CM001792_gene2506 6.7e-11 68.9 COG4733@1|root,COG4733@2|Bacteria,1UX6J@1239|Firmicutes,4I2IK@91061|Bacilli,23MSY@182709|Oceanobacillus 91061|Bacilli S gp58-like protein - - - - - - - - - - - - Gp58,Peptidase_S74 k59_578609_1 1173709.M3VMK9_9CIRC 2.48e-39 137.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_518138_1 1088869.GMO_04990 3.26e-06 55.5 COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,2TRAA@28211|Alphaproteobacteria,2JQ9B@204441|Rhodospirillales 204441|Rhodospirillales L Belongs to the 'phage' integrase family. XerC subfamily xerD - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase k59_189086_1 49964.Q94MS1_9CAUD 1.46e-77 241.0 4QB4H@10239|Viruses,4QYQI@35237|dsDNA viruses no RNA stage,4QUAR@28883|Caudovirales,4QNUV@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_496936_1 145579.CAPSD_BPPHM 6.7e-31 124.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_393838_1 1321778.HMPREF1982_02475 6e-11 68.2 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,2487V@186801|Clostridia,26AU2@186813|unclassified Clostridiales 186801|Clostridia L DNA polymerase A domain - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_477697_1 1348663.KCH_49510 1.62e-18 88.6 COG0438@1|root,COG0438@2|Bacteria,2HH27@201174|Actinobacteria 201174|Actinobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 k59_189108_1 1348908.KI518589_gene2556 1.7e-70 233.0 COG0417@1|root,COG0417@2|Bacteria,1TQJQ@1239|Firmicutes,4HF6F@91061|Bacilli,1ZF50@1386|Bacillus 91061|Bacilli L DNA polymerase elongation subunit (Family B) - - - - - - - - - - - - DNA_pol_B k59_518207_1 1397284.AYMN01000081_gene2459 1.01e-21 94.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,1RP8Z@1236|Gammaproteobacteria,402XD@613|Serratia 1236|Gammaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_518207_2 762660.E5EYJ6_9CAUD 9.4e-12 68.6 4QAKE@10239|Viruses,4QUP7@35237|dsDNA viruses no RNA stage,4QPCE@28883|Caudovirales,4QI56@10662|Myoviridae 10662|Myoviridae S nucleic acid binding - - - - - - - - - - - - - k59_456361_1 42345.XP_008808520.1 1.42e-33 135.0 28HK1@1|root,2QPXS@2759|Eukaryota,37NXW@33090|Viridiplantae,3GF00@35493|Streptophyta,3KSZH@4447|Liliopsida 35493|Streptophyta L Toprim domain - GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003697,GO:0003824,GO:0003896,GO:0003899,GO:0004003,GO:0004386,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016043,GO:0016070,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032392,GO:0032508,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051276,GO:0055086,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090407,GO:0097159,GO:0097747,GO:0140097,GO:0140098,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - DnaB_C,Toprim_4 k59_311433_1 1089549.AZUQ01000001_gene1354 2.08e-05 53.1 COG5519@1|root,COG5519@2|Bacteria,2I395@201174|Actinobacteria,4F07U@85014|Glycomycetales 201174|Actinobacteria L Bifunctional DNA primase/polymerase, N-terminal - - - - - - - - - - - - Prim-Pol k59_538921_2 691965.D4P7D3_9CAUD 1.49e-40 147.0 4QAYV@10239|Viruses,4QUZ7@35237|dsDNA viruses no RNA stage,4QPU3@28883|Caudovirales,4QKKX@10699|Siphoviridae 10699|Siphoviridae S Phage portal protein - - - - - - - - - - - - - k59_192002_2 3055.EDP07404 9.47e-07 57.8 KOG4275@1|root,KOG4275@2759|Eukaryota,37WKY@33090|Viridiplantae,34I7Q@3041|Chlorophyta 3041|Chlorophyta O Epidermal growth factor-like domain. - - - ko:K06236 ko04151,ko04510,ko04512,ko04611,ko04926,ko04933,ko04974,ko05146,ko05165,map04151,map04510,map04512,map04611,map04926,map04933,map04974,map05146,map05165 - - - ko00000,ko00001,ko00536,ko04516 - - - EGF_2,zf-C3HC4_3 k59_560584_8 1112217.PPL19_05125 4.87e-12 77.8 COG5185@1|root,COG5185@2|Bacteria,1QV8Y@1224|Proteobacteria,1T2AE@1236|Gammaproteobacteria 1236|Gammaproteobacteria D tail protein - - - - - - - - - - - - TMP_2,Tape_meas_lam_C k59_8040_2 1618248.A0A0C5IB82_9CIRC 1.67e-20 92.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_232124_1 1211115.ALIQ01000188_gene622 5.9e-39 148.0 COG0749@1|root,COG0749@2|Bacteria,1MWX7@1224|Proteobacteria,2UNT9@28211|Alphaproteobacteria 28211|Alphaproteobacteria L COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A,DNA_pol_A_exo1 k59_645591_1 1120792.JAFV01000001_gene3544 1.04e-19 91.3 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2TSDW@28211|Alphaproteobacteria,36Z9P@31993|Methylocystaceae 28211|Alphaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_581864_1 1278971.AOGF01000029_gene2248 5.32e-07 49.3 2BR5Y@1|root,32K42@2|Bacteria,1QFDK@1224|Proteobacteria,1TFZN@1236|Gammaproteobacteria,1YAIH@135625|Pasteurellales 1278971.AOGF01000029_gene2248|- - - - - - - - - - - - - - - - k59_543005_2 1122201.AUAZ01000017_gene2947 1.4e-26 109.0 COG0749@1|root,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,465DD@72275|Alteromonadaceae 1236|Gammaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity - - - - - - - - - - - - DNA_pol_A k59_131300_2 1589746.A0A0B5A6P7_9CAUD 1.93e-14 77.8 4QB5I@10239|Viruses,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_561202_1 1382356.JQMP01000004_gene63 1.93e-12 73.6 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2G5J0@200795|Chloroflexi,27Y2S@189775|Thermomicrobia 189775|Thermomicrobia L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_543019_1 1234888.K0A2J2_9VIRU 2.94e-56 191.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_151047_3 1609634.A0A0C5AFT2_9VIRU 2.39e-08 62.4 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_623612_1 351607.Acel_0467 2.12e-08 60.5 COG1737@1|root,COG1737@2|Bacteria,2GMG0@201174|Actinobacteria,4ESQ5@85013|Frankiales 201174|Actinobacteria K Sugar isomerase (SIS) - - 5.3.1.8,5.3.1.9 ko:K15916 ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R01819,R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000 - - - bact-PGI_C k59_337867_2 411463.EUBVEN_01889 2.94e-06 55.5 COG1372@1|root,COG5444@1|root,COG1372@2|Bacteria,COG5444@2|Bacteria,1VH6J@1239|Firmicutes,24Q2W@186801|Clostridia 186801|Clostridia L Hint (Hedgehog/Intein) domain N-terminal region - - - - - - - - - - - - PT-HINT k59_482289_1 1234888.K0A2J2_9VIRU 9.31e-67 222.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_445698_1 272559.BF9343_2354 9.15e-17 83.2 COG1196@1|root,COG1196@2|Bacteria,4NMBI@976|Bacteroidetes,2FR6N@200643|Bacteroidia 976|Bacteroidetes D nuclear chromosome segregation - - - - - - - - - - - - - k59_50692_1 942016.E9NIJ0_9CAUD 7.03e-34 129.0 4QF0B@10239|Viruses,4QX8P@35237|dsDNA viruses no RNA stage,4QSJT@28883|Caudovirales,4QNNK@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_318494_1 762982.HMPREF9442_00539 5.99e-16 84.0 COG1061@1|root,COG1061@2|Bacteria,4NECV@976|Bacteroidetes,2FN7J@200643|Bacteroidia 976|Bacteroidetes L Helicase C-terminal domain protein - - - ko:K19789 - - - - ko00000,ko03400 - - - Helicase_C,QSregVF_b,ResIII k59_111178_2 1114922.CIFAM_23_00300 1.03e-05 56.2 COG2304@1|root,COG2373@1|root,COG2304@2|Bacteria,COG2373@2|Bacteria,1QU09@1224|Proteobacteria,1T271@1236|Gammaproteobacteria,3WX4U@544|Citrobacter 1236|Gammaproteobacteria S Bacterial Ig-like domain (group 3) - - - ko:K20276 ko02024,map02024 - - - ko00000,ko00001 - - - Big_3_2 k59_97284_1 1692253.A0A0K1RLM4_9CIRC 6.55e-40 149.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_565303_1 621372.ACIH01000244_gene1333 1.29e-10 67.4 COG0433@1|root,COG0433@2|Bacteria,1V130@1239|Firmicutes,4HFW9@91061|Bacilli,26VCZ@186822|Paenibacillaceae 91061|Bacilli S COG0433 Predicted ATPase - - - - - - - - - - - - DUF87,TrwB_AAD_bind k59_586131_3 216432.CA2559_11618 3.22e-24 97.8 2DMPB@1|root,32SV8@2|Bacteria,4NSG4@976|Bacteroidetes,1I3FJ@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_586131_4 1056512.D515_00209 0.000673 42.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XSRH@135623|Vibrionales 135623|Vibrionales T signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - - - - - - - - - - EAL,GGDEF,PAS_3,PAS_9 k59_343367_1 865938.Weevi_0273 2.43e-13 69.3 2CF43@1|root,33249@2|Bacteria,4NUU3@976|Bacteroidetes,1I6X0@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_73293_1 1379725.S5TMY9_9CIRC 4.62e-20 92.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_445753_1 5759.rna_EHI_193630-1 2.75e-19 87.0 2CSEE@1|root,2RBK2@2759|Eukaryota,3X9MH@554915|Amoebozoa 554915|Amoebozoa G RNA helicase - - - - - - - - - - - - RNA_helicase k59_12922_1 1788454.A0A190WHE4_9CIRC 9.05e-43 150.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_381379_2 1692.BMAGN_0502 1.01e-30 122.0 COG0438@1|root,COG0438@2|Bacteria,2GP0E@201174|Actinobacteria,4CZN5@85004|Bifidobacteriales 201174|Actinobacteria M Glycosyl transferase 4-like domain - - 2.4.1.345 ko:K08256 - - R11702 - ko00000,ko01000,ko01003 - GT4 - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 k59_606922_1 691965.D4P7L7_9CAUD 5.16e-95 306.0 4QB9J@10239|Viruses,4QXFE@35237|dsDNA viruses no RNA stage,4QS1Z@28883|Caudovirales,4QN8F@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_568235_2 948565.AFFP02000001_gene880 2.17e-14 74.3 COG0577@1|root,COG1136@1|root,COG0577@2|Bacteria,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RNUJ@1236|Gammaproteobacteria,1Y7R7@135625|Pasteurellales 135625|Pasteurellales V Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides macB - - ko:K05685 ko02010,map02010 M00709 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.122.1,3.A.1.122.12 - - ABC_tran,FtsX,MacB_PCD k59_609973_1 1116472.MGMO_218c00040 4.15e-201 557.0 COG2367@1|root,COG2367@2|Bacteria,1NMW4@1224|Proteobacteria,1RWGW@1236|Gammaproteobacteria 1236|Gammaproteobacteria V Beta-lactamase bla - 3.5.2.6 ko:K17836,ko:K18698,ko:K18795,ko:K19217 ko00311,ko01130,ko01501,map00311,map01130,map01501 M00627,M00628 R06363 RC01499 br01600,ko00000,ko00001,ko00002,ko01000,ko01504 - - - Beta-lactamase2 k59_53441_2 94624.Bpet0954 2.61e-08 58.2 29ZTU@1|root,30MUV@2|Bacteria,1P9JK@1224|Proteobacteria 1224|Proteobacteria L HNH endonuclease - - - - - - - - - - - - HNH_3 k59_53441_3 1124991.MU9_2939 1.14e-50 170.0 28IQ7@1|root,2Z8PY@2|Bacteria,1NA66@1224|Proteobacteria,1S212@1236|Gammaproteobacteria 1236|Gammaproteobacteria S RecT family bet - - - - - - - - - - - RecT k59_114440_3 1052673.G1FGL3_9CAUD 4e-13 70.1 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales 28883|Caudovirales S HNH endonuclease - - - - - - - - - - - - - k59_114440_6 234621.RER_24950 1e-17 82.4 COG3541@1|root,COG3541@2|Bacteria 2|Bacteria L Predicted nucleotidyltransferase - - - ko:K07074 - - - - ko00000 - - - Nuc-transf k59_115124_2 1121924.ATWH01000001_gene4299 1.15e-11 72.0 COG3291@1|root,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria,4FKX3@85023|Microbacteriaceae 201174|Actinobacteria G Repeats in polycystic kidney disease 1 (PKD1) and other proteins wcoG - - - - - - - - - - - Laminin_G_3,PKD k59_468711_1 926562.Oweho_2253 5.66e-07 56.2 COG4409@1|root,COG4409@2|Bacteria 2|Bacteria G exo-alpha-(2->6)-sialidase activity - - - - - - - - - - - - BNR_2,Gram_pos_anchor k59_426670_1 691965.D4P7I3_9CAUD 2.21e-13 72.4 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_426670_4 478749.BRYFOR_08565 4.46e-54 184.0 2A0KC@1|root,2ZGJK@2|Bacteria,1V2JS@1239|Firmicutes,24H6R@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_426670_5 691965.D4P7H8_9CAUD 8.1e-28 112.0 4QG1E@10239|Viruses,4QZE1@35237|dsDNA viruses no RNA stage,4QU6Q@28883|Caudovirales,4QMKH@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_140668_1 487521.OCU_06970 2.03e-13 77.4 2EP1Y@1|root,33GNT@2|Bacteria,2IC2I@201174|Actinobacteria,2380S@1762|Mycobacteriaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_451070_1 1121920.AUAU01000009_gene1881 6.37e-42 177.0 COG1520@1|root,COG1520@2|Bacteria 2|Bacteria S amino acid activation for nonribosomal peptide biosynthetic process - - - - - - - - - - - - He_PIG,I-set,Ig_3,PKD,Peptidase_S8 k59_281890_1 1692253.A0A0K1RLM4_9CIRC 8.56e-12 72.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_468745_1 640132.Srot_1173 4.36e-18 87.0 COG0270@1|root,COG0270@2|Bacteria,2GJR6@201174|Actinobacteria 2|Bacteria H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family dcm - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_240402_1 320837.Q4ZCU6_9CAUD 4.13e-114 350.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_263509_2 1172188.KB911820_gene2875 2.3e-34 132.0 COG0358@1|root,COG0358@2|Bacteria 2|Bacteria L DNA primase activity - - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - AAA_25,Toprim_2,Toprim_N,zf-CHC2 k59_158553_1 2003327.CAPSD_BPCHP 1.92e-46 167.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_217777_1 1414738.V5UQL8_9CAUD 1.2e-61 211.0 4QGA5@10239|Viruses,4QURD@35237|dsDNA viruses no RNA stage,4QT9N@28883|Caudovirales,4QP47@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_322831_2 1411123.JQNH01000001_gene98 2.86e-12 74.3 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2TQZE@28211|Alphaproteobacteria 28211|Alphaproteobacteria M COG0739 Membrane proteins related to metalloendopeptidases MA20_30780 - - - - - - - - - - - Peptidase_M23 k59_632116_1 942016.E9NIJ0_9CAUD 1.28e-18 85.9 4QF0B@10239|Viruses,4QX8P@35237|dsDNA viruses no RNA stage,4QSJT@28883|Caudovirales,4QNNK@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_263528_1 398720.MED217_15260 6.84e-14 78.2 COG5295@1|root,COG5295@2|Bacteria,4NJTK@976|Bacteroidetes,1HZNB@117743|Flavobacteriia 976|Bacteroidetes UW surface antigen - - - - - - - - - - - - Peptidase_S74 k59_515081_1 880071.Fleli_0208 2.35e-24 108.0 COG4974@1|root,COG4974@2|Bacteria,4P9HB@976|Bacteroidetes,47RB2@768503|Cytophagia 976|Bacteroidetes L Phage integrase family - - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase k59_22302_1 1120979.ATVB01000007_gene1117 0.000536 50.1 28MKK@1|root,2ZAWR@2|Bacteria,2IS2W@201174|Actinobacteria,4D1DD@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - RNA_helicase,Viral_Rep k59_638023_1 764299.STRIC_2124 1.87e-09 62.0 2DR9Y@1|root,33AUY@2|Bacteria,1VEP1@1239|Firmicutes,4HP3X@91061|Bacilli 91061|Bacilli L NUMOD4 motif - - - - - - - - - - - - HNH_3,NUMOD4 k59_350311_3 1219084.AP014508_gene2062 2.38e-57 196.0 COG0381@1|root,COG0381@2|Bacteria,2GC04@200918|Thermotogae 200918|Thermotogae G Belongs to the UDP-N-acetylglucosamine 2-epimerase family - - 5.1.3.14 ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420 RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Epimerase_2 k59_145441_1 1692253.A0A0K1RLM4_9CIRC 1.2e-21 97.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_248418_1 1795983.A0A140CTJ3_9CIRC 9.81e-14 75.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_288858_2 1234888.K0A2J2_9VIRU 3.53e-50 175.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_515136_2 268739.Nmlp_1807 8.68e-05 45.1 COG0210@1|root,arCOG00797@2157|Archaea,2XUH7@28890|Euryarchaeota,23S3W@183963|Halobacteria 183963|Halobacteria L COG0210 Superfamily I DNA and RNA helicases uvrD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k59_124825_1 1234888.K0A2J2_9VIRU 1.37e-49 177.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_268992_1 393283.XP_007828957.1 1.17e-08 63.5 COG0553@1|root,KOG1001@2759|Eukaryota,39YMI@33154|Opisthokonta,3P18K@4751|Fungi,3QPWG@4890|Ascomycota,21DQZ@147550|Sordariomycetes 4751|Fungi A helicase superfamily c-terminal domain - - - - - - - - - - - - Helicase_C,SNF2_N k59_42959_1 745411.B3C1_16566 2.76e-44 152.0 COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,1RMG9@1236|Gammaproteobacteria,1J5W1@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) queC - 6.3.4.20 ko:K06920 ko00790,ko01100,map00790,map01100 - R09978 RC00959 ko00000,ko00001,ko01000,ko03016 - - - QueC k59_309290_1 1123388.AQWU01000072_gene1403 7.25e-12 67.8 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1WJ4Q@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) - - 2.7.9.1 ko:K01006 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 M00169,M00171,M00172,M00173 R00206 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N k59_309290_2 67257.JODR01000002_gene1131 7.22e-13 72.8 COG2453@1|root,COG2453@2|Bacteria,2IHXA@201174|Actinobacteria 201174|Actinobacteria T phosphatase - - - - - - - - - - - - Y_phosphatase k59_521312_1 1556290.A0A0A0RQI3_9CAUD 2.97e-75 254.0 4QCZC@10239|Viruses,4QRH3@28883|Caudovirales,4QM07@10699|Siphoviridae 10699|Siphoviridae S Bacterial DNA polymerase III alpha subunit - - - - - - - - - - - - - k59_601356_1 1133569.AHYZ01000082_gene384 8.79e-29 119.0 COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,4HAWN@91061|Bacilli,3F3JW@33958|Lactobacillaceae 91061|Bacilli L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge k59_150145_4 1242969.ATCC51562_1773 1.94e-09 56.6 COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,42U7E@68525|delta/epsilon subdivisions,2YPT9@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 k59_458607_1 1618237.A0A0C5IMG6_9CIRC 7.2e-16 80.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_458607_2 1692244.A0A0K1RLR5_9CIRC 1.89e-29 114.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_294072_1 1137745.H6WFW1_9CAUD 3.08e-09 63.2 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QI82@10662|Myoviridae 10662|Myoviridae S virus tail, fiber - GO:0005575,GO:0019012 - - - - - - - - - - - k59_313288_3 536233.CLO_1816 2.11e-115 337.0 COG0863@1|root,COG0863@2|Bacteria,1V0ZF@1239|Firmicutes,24CQV@186801|Clostridia,36J76@31979|Clostridiaceae 186801|Clostridia L Belongs to the N(4) N(6)-methyltransferase family - - - - - - - - - - - - N6_N4_Mtase k59_521333_1 428125.CLOLEP_01415 1.09e-34 126.0 28NM4@1|root,2ZBMQ@2|Bacteria,1V1QD@1239|Firmicutes,24G1B@186801|Clostridia,3WNFY@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_521333_2 428125.CLOLEP_01417 1.05e-52 173.0 2CGG9@1|root,2ZVSJ@2|Bacteria,1V633@1239|Firmicutes,24HD0@186801|Clostridia,3WMXK@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_580836_3 410359.Pcal_1351 3.32e-09 58.9 arCOG05626@1|root,arCOG05626@2157|Archaea 2157|Archaea - - - - - - - - - - - - - - - k59_89974_1 1454007.JAUG01000005_gene2805 4.81e-83 256.0 COG0270@1|root,COG0270@2|Bacteria,4NJPP@976|Bacteroidetes,1IYYG@117747|Sphingobacteriia 976|Bacteroidetes L C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_150179_1 1168478.I6R9L7_9CAUD 8.47e-45 151.0 4QBFR@10239|Viruses,4QV1E@35237|dsDNA viruses no RNA stage,4QPRX@28883|Caudovirales,4QKMP@10699|Siphoviridae 10699|Siphoviridae S ERF superfamily - - - - - - - - - - - - - k59_625559_2 1127696.HMPREF9134_01826 1.05e-55 181.0 28HFG@1|root,2Z7RJ@2|Bacteria,4NFNY@976|Bacteroidetes,2FKZK@200643|Bacteroidia,22X14@171551|Porphyromonadaceae 976|Bacteroidetes S Domain of Unknown Function (DUF1599) - - - - - - - - - - - - DUF1599 k59_109561_1 1618238.A0A0C5IB41_9CIRC 3.65e-06 56.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_525380_1 693582.D2EBT0_9CAUD 1.4e-14 74.7 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales,4QNBQ@10744|Podoviridae 10744|Podoviridae S HNH endonuclease - - - - - - - - - - - - - k59_461622_1 587753.EY04_06585 4.16e-16 81.6 COG0582@1|root,COG0582@2|Bacteria,1MVZB@1224|Proteobacteria,1RSCD@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Belongs to the 'phage' integrase family - - - ko:K14059 - - - - ko00000 - - - Arm-DNA-bind_2,Phage_int_SAM_4,Phage_integrase k59_194484_2 479433.Caci_0336 1.56e-56 183.0 COG0629@1|root,COG0629@2|Bacteria,2GMM3@201174|Actinobacteria 201174|Actinobacteria L single-stranded DNA-binding protein ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_545625_3 1204521.I7A8N0_9CAUD 3.11e-60 198.0 4QAUS@10239|Viruses,4QURX@35237|dsDNA viruses no RNA stage,4QQ2S@28883|Caudovirales 28883|Caudovirales S flavin adenine dinucleotide binding - - - - - - - - - - - - - k59_234587_1 1458357.BG58_11025 1.44e-11 68.2 COG2197@1|root,COG2197@2|Bacteria,1NA3X@1224|Proteobacteria,2VWX0@28216|Betaproteobacteria,1KAW7@119060|Burkholderiaceae 28216|Betaproteobacteria KT phage-related functions and prophages - - - - - - - - - - - - HNH_3 k59_94786_1 1327981.S0A2H8_9CAUD 2.1e-36 141.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0019012,GO:0019028,GO:0042802,GO:0044423 - - - - - - - - - - - k59_546292_1 411460.RUMTOR_01350 1.55e-05 49.3 2EAAT@1|root,334F2@2|Bacteria,1VJJI@1239|Firmicutes,24TQU@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_109866_1 1385658.U5KPZ6_9VIRU 1.6e-47 167.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_109866_3 1385658.U5KNR1_9VIRU 6.23e-81 254.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_316721_1 7176.CPIJ008169-PA 4.86e-11 62.4 2E4T1@1|root,2SBN4@2759|Eukaryota,3ADG2@33154|Opisthokonta,3BWF0@33208|Metazoa,3DCTZ@33213|Bilateria 33208|Metazoa - - - - - - - - - - - - - - - k59_10842_1 1118059.CAHC01000010_gene88 1.75e-52 195.0 COG0749@1|root,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia,3WCFG@538999|Clostridiales incertae sedis 186801|Clostridia L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_420571_1 649349.Lbys_0384 1.06e-48 182.0 COG3209@1|root,COG3209@2|Bacteria,4PKBQ@976|Bacteroidetes,47XXU@768503|Cytophagia 976|Bacteroidetes M SprB repeat - - - - - - - - - - - - CHU_C,SdrD_B,SprB k59_175347_3 1458670.W8NP27_9CAUD 1.42e-09 59.7 4QF38@10239|Viruses,4QUXM@35237|dsDNA viruses no RNA stage,4QTDX@28883|Caudovirales,4QMUM@10699|Siphoviridae 10699|Siphoviridae S AAA domain - - - - - - - - - - - - - k59_585501_1 655097.C8ZKD4_9CAUD 5.37e-18 86.7 4QBY0@10239|Viruses,4QW35@35237|dsDNA viruses no RNA stage,4QQ4Q@28883|Caudovirales,4QNNN@10744|Podoviridae 10744|Podoviridae S UvrD-like helicase C-terminal domain - - - - - - - - - - - - - k59_258176_1 298386.PBPRA1531 2.15e-07 57.8 COG0417@1|root,COG0417@2|Bacteria,1MVY9@1224|Proteobacteria,1RMQ1@1236|Gammaproteobacteria,1XTIT@135623|Vibrionales 135623|Vibrionales L COG0417 DNA polymerase elongation subunit (family B) - - 2.7.7.7 ko:K02336 - - - - ko00000,ko01000,ko03400 - - - DNA_pol_B,DNA_pol_B_exo1 k59_380736_7 926562.Oweho_0361 7.4e-57 181.0 COG3108@1|root,COG3108@2|Bacteria,4NSZA@976|Bacteroidetes,1I46U@117743|Flavobacteriia 976|Bacteroidetes S Peptidase M15 - - - - - - - - - - - - Peptidase_M15_3 k59_176714_1 1192034.CAP_7645 2.52e-28 114.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,42M7X@68525|delta/epsilon subdivisions,2WJCA@28221|Deltaproteobacteria,2YTXF@29|Myxococcales 28221|Deltaproteobacteria L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_176714_2 1120999.JONM01000023_gene3155 1.01e-13 68.6 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,2VR2Z@28216|Betaproteobacteria,2KQZB@206351|Neisseriales 206351|Neisseriales L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_487286_4 264731.PRU_2485 1.83e-21 107.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,2FM8X@200643|Bacteroidia 976|Bacteroidetes L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_110715_1 679201.HMPREF9334_00311 1.9e-26 113.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4H2W4@909932|Negativicutes 909932|Negativicutes L SNF2 family - - - - - - - - - - - - Helicase_C,SNF2_N k59_236570_1 1150621.SMUL_2941 5.72e-20 90.9 COG0790@1|root,COG0790@2|Bacteria,1QWUU@1224|Proteobacteria 1224|Proteobacteria S T5orf172 - - - - - - - - - - - - T5orf172 k59_464310_1 1476390.A0A060RFG9_9CAUD 4.28e-13 71.6 4QBA5@10239|Viruses,4QXFW@35237|dsDNA viruses no RNA stage,4QPTU@28883|Caudovirales,4QN4A@10699|Siphoviridae 10699|Siphoviridae S AAA domain - - - - - - - - - - - - - k59_258984_1 202752.JL53_03695 7.24e-06 52.4 COG0417@1|root,COG0417@2|Bacteria,1TQJQ@1239|Firmicutes,4HF6F@91061|Bacilli 91061|Bacilli L DNA polymerase elongation subunit (Family B) - - - - - - - - - - - - DNA_pol_B k59_299393_1 641491.DND132_2087 2.19e-83 263.0 COG5323@1|root,COG5323@2|Bacteria,1R049@1224|Proteobacteria,42UYF@68525|delta/epsilon subdivisions,2WQN3@28221|Deltaproteobacteria,2M90K@213115|Desulfovibrionales 28221|Deltaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6 k59_401387_2 521674.Plim_0508 2.06e-12 67.0 COG0073@1|root,COG0073@2|Bacteria,2IYR2@203682|Planctomycetes 203682|Planctomycetes J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation - - - - - - - - - - - - RNA_ligase k59_236586_1 1156844.KB891809_gene7935 1.23e-15 83.2 COG0791@1|root,COG3409@1|root,COG0791@2|Bacteria,COG3409@2|Bacteria,2I61A@201174|Actinobacteria 201174|Actinobacteria M Peptidoglycan-binding domain 1 protein - - - - - - - - - - - - NLPC_P60,PG_binding_1 k59_318598_1 1217713.F993_01297 0.000357 44.7 2AZHX@1|root,31RS4@2|Bacteria,1QP97@1224|Proteobacteria,1TMYJ@1236|Gammaproteobacteria,3NPPM@468|Moraxellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_548958_2 1037409.BJ6T_36040 7.87e-18 89.7 COG4675@1|root,COG4675@2|Bacteria,1R7VJ@1224|Proteobacteria,2V8US@28211|Alphaproteobacteria,3JUWZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Phage Tail Collar Domain - - - - - - - - - - - - Collar k59_464330_1 488538.SAR116_0552 1.56e-17 80.9 COG3091@1|root,COG3091@2|Bacteria,1NK2B@1224|Proteobacteria 1224|Proteobacteria S SprT homologues. - - - - - - - - - - - - SprT-like k59_450592_1 1327981.S0A2J0_9CAUD 0.000862 45.1 4QB2X@10239|Viruses,4QXYM@35237|dsDNA viruses no RNA stage,4QRYM@28883|Caudovirales,4QMB2@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_181859_1 11082.PRO_0000037746 3.08e-106 323.0 4QBXT@10239|Viruses,4R138@439488|ssRNA viruses,4R0R1@35278|ssRNA positive-strand viruses no DNA stage 10239|Viruses K ATP-dependent helicase activity - GO:0001510,GO:0001959,GO:0001960,GO:0002682,GO:0002683,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003725,GO:0003727,GO:0003824,GO:0004482,GO:0004483,GO:0005488,GO:0005575,GO:0006139,GO:0006370,GO:0006396,GO:0006397,GO:0006508,GO:0006725,GO:0006807,GO:0006810,GO:0006897,GO:0006898,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008171,GO:0008173,GO:0008174,GO:0008233,GO:0008757,GO:0009451,GO:0009452,GO:0009605,GO:0009607,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009966,GO:0009968,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010646,GO:0010648,GO:0010941,GO:0016032,GO:0016070,GO:0016071,GO:0016192,GO:0016556,GO:0016740,GO:0016741,GO:0016787,GO:0018995,GO:0019012,GO:0019031,GO:0019048,GO:0019049,GO:0019050,GO:0019054,GO:0019058,GO:0019065,GO:0019068,GO:0019219,GO:0019222,GO:0019538,GO:0020012,GO:0023051,GO:0023057,GO:0030260,GO:0030430,GO:0030682,GO:0030683,GO:0031323,GO:0031324,GO:0031329,GO:0031330,GO:0031347,GO:0031348,GO:0032259,GO:0032991,GO:0032993,GO:0033592,GO:0033643,GO:0033646,GO:0033655,GO:0033668,GO:0034641,GO:0035821,GO:0036260,GO:0036265,GO:0036338,GO:0039502,GO:0039503,GO:0039526,GO:0039713,GO:0039714,GO:0042981,GO:0043067,GO:0043069,GO:0043170,GO:0043207,GO:0043412,GO:0043414,GO:0043487,GO:0043489,GO:0043656,GO:0043657,GO:0043900,GO:0043902,GO:0043903,GO:0044003,GO:0044068,GO:0044215,GO:0044216,GO:0044217,GO:0044237,GO:0044238,GO:0044260,GO:0044403,GO:0044409,GO:0044413,GO:0044414,GO:0044415,GO:0044419,GO:0044423,GO:0044501,GO:0044531,GO:0044532,GO:0044766,GO:0045069,GO:0045070,GO:0045088,GO:0045824,GO:0045934,GO:0046483,GO:0046718,GO:0046755,GO:0046762,GO:0046794,GO:0048518,GO:0048519,GO:0048523,GO:0048524,GO:0048583,GO:0048585,GO:0050690,GO:0050776,GO:0050777,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051252,GO:0051253,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051806,GO:0051807,GO:0051817,GO:0051828,GO:0051832,GO:0051833,GO:0051834,GO:0052027,GO:0052029,GO:0052031,GO:0052037,GO:0052040,GO:0052041,GO:0052150,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052248,GO:0052250,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052433,GO:0052490,GO:0052493,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0060147,GO:0060149,GO:0060255,GO:0060338,GO:0060339,GO:0060548,GO:0060759,GO:0060761,GO:0060966,GO:0060967,GO:0060968,GO:0060969,GO:0065007,GO:0065008,GO:0071704,GO:0072583,GO:0075109,GO:0075111,GO:0075112,GO:0075114,GO:0075136,GO:0075509,GO:0075512,GO:0075528,GO:0080009,GO:0080090,GO:0080134,GO:0090304,GO:0097159,GO:0097617,GO:0098657,GO:0106005,GO:0140096,GO:0140098,GO:1900368,GO:1900369,GO:1901360,GO:1901363,GO:1901564,GO:1902369,GO:1902579,GO:1903900,GO:1903902,GO:1990814,GO:1990904 - - - - - - - - - - - k59_589677_4 1454004.AW11_01751 1.8e-09 60.1 COG0791@1|root,COG0791@2|Bacteria,1N0EE@1224|Proteobacteria,2VSHN@28216|Betaproteobacteria,1KQUF@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria M Cell envelope biogenesis, outer membrane - - - ko:K13695,ko:K19303 - - - - ko00000,ko01000,ko01002,ko01011 - - - NLPC_P60 k59_589677_5 936136.ARRT01000006_gene4457 4.56e-13 80.9 COG4733@1|root,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria,2TV2W@28211|Alphaproteobacteria,4BIQV@82115|Rhizobiaceae 28211|Alphaproteobacteria S COG4733 Phage-related protein, tail component - - - - - - - - - - - - Phage-tail_3 k59_16683_2 748727.CLJU_c03660 4.38e-31 133.0 COG5283@1|root,COG5412@1|root,COG5283@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,247QT@186801|Clostridia,36E7F@31979|Clostridiaceae 186801|Clostridia M tail tape measure protein - - - - - - - - - - - - PhageMin_Tail k59_114807_1 105154.Q9MBU6_9VIRU 5.09e-66 219.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_158204_2 2003327.CAPSD_BPCHP 1.7e-24 106.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_102418_2 1109717.G9FGV8_9CAUD 7.48e-42 163.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_568578_2 691965.D4P7H8_9CAUD 2e-20 89.7 4QG1E@10239|Viruses,4QZE1@35237|dsDNA viruses no RNA stage,4QU6Q@28883|Caudovirales,4QMKH@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_361684_1 1234888.K0A2J2_9VIRU 1.32e-84 269.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_450668_1 1379695.S5TNA9_9CIRC 5.11e-73 227.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_450668_5 1379695.S5TNA9_9CIRC 4.76e-75 235.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_469182_1 942016.E9NIF8_9CAUD 5.78e-50 172.0 4QAR1@10239|Viruses,4QUNA@35237|dsDNA viruses no RNA stage,4QPJE@28883|Caudovirales,4QNDS@10744|Podoviridae 10744|Podoviridae S ATPase activity - - - - - - - - - - - - - k59_632475_1 105154.Q9MBU6_9VIRU 1.62e-111 337.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_498642_3 1234888.K0A2J2_9VIRU 1.05e-34 132.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_231275_1 926560.KE387023_gene1353 5.73e-52 176.0 COG0582@1|root,COG0582@2|Bacteria,1WM1D@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus L Phage integrase family - - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_integrase k59_7008_1 1476876.JOJO01000002_gene6625 2.06e-33 127.0 COG1088@1|root,COG1088@2|Bacteria,2GNDU@201174|Actinobacteria 2|Bacteria M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily rfbB - 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd k59_645212_1 1173762.S4TP28_9CAUD 8.44e-74 244.0 4QGA5@10239|Viruses,4QURD@35237|dsDNA viruses no RNA stage,4QT9N@28883|Caudovirales,4QP47@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_521654_1 1173762.S4TRN6_9CAUD 1.83e-25 105.0 4QBMV@10239|Viruses,4QUU6@35237|dsDNA viruses no RNA stage,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_273502_1 391587.KAOT1_03317 2.71e-09 68.2 COG4886@1|root,COG4886@2|Bacteria,4NF17@976|Bacteroidetes,1IJNI@117743|Flavobacteriia 976|Bacteroidetes O Mycoplasma protein of unknown function, DUF285 - - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - BACON,DUF285,LRR_5 k59_27292_1 118797.XP_007464375.1 5.67e-12 70.9 COG2453@1|root,KOG1716@2759|Eukaryota,39T0V@33154|Opisthokonta,3B93R@33208|Metazoa,3D04V@33213|Bilateria,487CH@7711|Chordata,4959H@7742|Vertebrata,3J7EN@40674|Mammalia,4J0Y5@91561|Cetartiodactyla 33208|Metazoa V dual specificity DUSP10 GO:0000188,GO:0001932,GO:0001933,GO:0002237,GO:0002682,GO:0002683,GO:0002684,GO:0002694,GO:0002696,GO:0002697,GO:0002698,GO:0002819,GO:0003674,GO:0003824,GO:0004721,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005794,GO:0005829,GO:0006464,GO:0006469,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0007275,GO:0007399,GO:0007417,GO:0008150,GO:0008152,GO:0008285,GO:0008330,GO:0008432,GO:0009605,GO:0009607,GO:0009617,GO:0009892,GO:0009966,GO:0009968,GO:0009987,GO:0010001,GO:0010033,GO:0010563,GO:0010605,GO:0010632,GO:0010633,GO:0010646,GO:0010648,GO:0010721,GO:0012505,GO:0014013,GO:0014014,GO:0016311,GO:0016604,GO:0016607,GO:0016787,GO:0016788,GO:0016791,GO:0019220,GO:0019222,GO:0019538,GO:0019899,GO:0019900,GO:0019901,GO:0022008,GO:0022407,GO:0022409,GO:0023051,GO:0023057,GO:0030154,GO:0030155,GO:0030334,GO:0030336,GO:0031323,GO:0031324,GO:0031347,GO:0031348,GO:0031399,GO:0031400,GO:0031974,GO:0031981,GO:0032101,GO:0032102,GO:0032268,GO:0032269,GO:0032496,GO:0032501,GO:0032502,GO:0032872,GO:0032873,GO:0032879,GO:0033549,GO:0033673,GO:0033993,GO:0035335,GO:0035970,GO:0036211,GO:0040008,GO:0040012,GO:0040013,GO:0042063,GO:0042127,GO:0042221,GO:0042325,GO:0042326,GO:0042578,GO:0043086,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043405,GO:0043407,GO:0043408,GO:0043409,GO:0043412,GO:0043506,GO:0043508,GO:0043549,GO:0044092,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044387,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0045088,GO:0045580,GO:0045582,GO:0045589,GO:0045591,GO:0045595,GO:0045596,GO:0045597,GO:0045598,GO:0045619,GO:0045621,GO:0045685,GO:0045686,GO:0045785,GO:0045824,GO:0045859,GO:0045926,GO:0045936,GO:0046328,GO:0046329,GO:0048273,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048638,GO:0048640,GO:0048699,GO:0048709,GO:0048713,GO:0048715,GO:0048731,GO:0048856,GO:0048869,GO:0050678,GO:0050680,GO:0050727,GO:0050728,GO:0050767,GO:0050768,GO:0050776,GO:0050777,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050863,GO:0050865,GO:0050867,GO:0050870,GO:0050896,GO:0051019,GO:0051093,GO:0051094,GO:0051171,GO:0051172,GO:0051174,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051248,GO:0051249,GO:0051251,GO:0051270,GO:0051271,GO:0051338,GO:0051348,GO:0051704,GO:0051707,GO:0051960,GO:0051961,GO:0060255,GO:0060263,GO:0060264,GO:0060266,GO:0060268,GO:0060284,GO:0061041,GO:0061045,GO:0065007,GO:0065009,GO:0070013,GO:0070302,GO:0070303,GO:0070372,GO:0070373,GO:0071704,GO:0071900,GO:0071901,GO:0080090,GO:0080134,GO:0080135,GO:0090335,GO:0140096,GO:1900744,GO:1901564,GO:1901700,GO:1902105,GO:1902107,GO:1902531,GO:1902532,GO:1903034,GO:1903035,GO:1903037,GO:1903039,GO:1903706,GO:1903708,GO:1903753,GO:1905041,GO:1905042,GO:1990264,GO:2000026,GO:2000145,GO:2000146 3.1.3.16,3.1.3.48 ko:K20216 ko04010,ko04013,ko04214,map04010,map04013,map04214 - - - ko00000,ko00001,ko01000,ko01009 - - - DSPc,Rhodanese k59_176620_1 97195.Q4JF81_HAV01 1.74e-42 174.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage 10239|Viruses S DNA polymerase family B - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004527,GO:0004540,GO:0005575,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016032,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0018130,GO:0018995,GO:0019058,GO:0019079,GO:0019438,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0039686,GO:0039693,GO:0042025,GO:0042221,GO:0043170,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044403,GO:0044419,GO:0046483,GO:0050896,GO:0051704,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140097,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902074 - - - - - - - - - - - k59_176620_2 128390.XP_009464505.1 8.5e-17 73.9 COG1552@1|root,KOG0003@2759|Eukaryota,39ZU5@33154|Opisthokonta,3BPCG@33208|Metazoa,3D67K@33213|Bilateria,48DZE@7711|Chordata,49AU8@7742|Vertebrata,4GV54@8782|Aves 33208|Metazoa J ubiquitin-60S ribosomal protein L40 UBA52 GO:0000122,GO:0000165,GO:0000184,GO:0000187,GO:0000209,GO:0000715,GO:0000731,GO:0000956,GO:0001666,GO:0001932,GO:0001934,GO:0002218,GO:0002221,GO:0002224,GO:0002253,GO:0002376,GO:0002682,GO:0002684,GO:0002753,GO:0002755,GO:0002756,GO:0002757,GO:0002758,GO:0002764,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005768,GO:0005783,GO:0005789,GO:0005791,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006283,GO:0006289,GO:0006294,GO:0006296,GO:0006297,GO:0006301,GO:0006355,GO:0006357,GO:0006401,GO:0006402,GO:0006412,GO:0006413,GO:0006464,GO:0006468,GO:0006508,GO:0006511,GO:0006518,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006625,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006886,GO:0006950,GO:0006974,GO:0006996,GO:0007031,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007178,GO:0007179,GO:0007249,GO:0007254,GO:0007267,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009628,GO:0009636,GO:0009719,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0010008,GO:0010033,GO:0010467,GO:0010468,GO:0010498,GO:0010556,GO:0010557,GO:0010558,GO:0010562,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0010646,GO:0010647,GO:0010648,GO:0010941,GO:0010942,GO:0012505,GO:0012506,GO:0015031,GO:0015833,GO:0015934,GO:0016020,GO:0016032,GO:0016043,GO:0016055,GO:0016070,GO:0016071,GO:0016192,GO:0016197,GO:0016310,GO:0016567,GO:0016579,GO:0017015,GO:0017085,GO:0018130,GO:0019058,GO:0019068,GO:0019219,GO:0019220,GO:0019221,GO:0019222,GO:0019438,GO:0019439,GO:0019538,GO:0019867,GO:0019941,GO:0019985,GO:0022607,GO:0022625,GO:0022626,GO:0023014,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030139,GO:0030163,GO:0030512,GO:0030522,GO:0030659,GO:0030666,GO:0030867,GO:0031090,GO:0031098,GO:0031145,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031329,GO:0031347,GO:0031349,GO:0031399,GO:0031401,GO:0031410,GO:0031966,GO:0031967,GO:0031968,GO:0031974,GO:0031975,GO:0031981,GO:0031982,GO:0031984,GO:0032147,GO:0032268,GO:0032270,GO:0032446,GO:0032991,GO:0033036,GO:0033365,GO:0033554,GO:0033674,GO:0033683,GO:0034097,GO:0034613,GO:0034622,GO:0034641,GO:0034645,GO:0034654,GO:0034655,GO:0035556,GO:0035666,GO:0035872,GO:0036211,GO:0036293,GO:0036294,GO:0036297,GO:0042175,GO:0042221,GO:0042276,GO:0042325,GO:0042327,GO:0042769,GO:0042886,GO:0042981,GO:0043043,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043085,GO:0043161,GO:0043170,GO:0043209,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043405,GO:0043406,GO:0043408,GO:0043410,GO:0043412,GO:0043487,GO:0043488,GO:0043549,GO:0043574,GO:0043603,GO:0043604,GO:0043618,GO:0043620,GO:0043632,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044391,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044429,GO:0044432,GO:0044433,GO:0044440,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044766,GO:0045047,GO:0045088,GO:0045089,GO:0045184,GO:0045859,GO:0045860,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045937,GO:0045944,GO:0046483,GO:0046700,GO:0046794,GO:0046907,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0050776,GO:0050778,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051090,GO:0051091,GO:0051092,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051252,GO:0051253,GO:0051254,GO:0051276,GO:0051338,GO:0051347,GO:0051403,GO:0051603,GO:0051606,GO:0051641,GO:0051649,GO:0051704,GO:0051716,GO:0055085,GO:0060255,GO:0060548,GO:0061013,GO:0061024,GO:0061418,GO:0065003,GO:0065004,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070423,GO:0070482,GO:0070498,GO:0070555,GO:0070646,GO:0070647,GO:0070727,GO:0070848,GO:0070887,GO:0070911,GO:0070972,GO:0070987,GO:0071310,GO:0071345,GO:0071347,GO:0071363,GO:0071453,GO:0071456,GO:0071495,GO:0071559,GO:0071560,GO:0071702,GO:0071704,GO:0071705,GO:0071824,GO:0071840,GO:0071897,GO:0071900,GO:0071902,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0072662,GO:0072663,GO:0075733,GO:0080090,GO:0080134,GO:0090092,GO:0090101,GO:0090150,GO:0090287,GO:0090288,GO:0090304,GO:0090305,GO:0097708,GO:0098552,GO:0098554,GO:0098556,GO:0098562,GO:0098588,GO:0098805,GO:0098827,GO:0198738,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1902531,GO:1902533,GO:1902579,GO:1902679,GO:1902680,GO:1903311,GO:1903506,GO:1903507,GO:1903508,GO:1903844,GO:1903845,GO:1905114,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - ko:K02927 ko03010,map03010 M00177,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L40e,ubiquitin k59_585450_1 279383.Q5DN81_9CAUD 5.72e-42 151.0 4QBA2@10239|Viruses,4QV98@35237|dsDNA viruses no RNA stage,4QPPI@28883|Caudovirales,4QM0B@10699|Siphoviridae 10699|Siphoviridae S Thymidylate synthase - GO:0003674,GO:0003824,GO:0004799,GO:0008150,GO:0008152,GO:0008168,GO:0016740,GO:0016741,GO:0032259,GO:0042083 - - - - - - - - - - - k59_214426_1 1327977.S0A018_9CAUD 0.00098 49.3 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QNBD@10744|Podoviridae 10744|Podoviridae S outer membrane - - - - - - - - - - - - - k59_487933_1 879305.HMPREF9290_0159 2.58e-11 66.6 COG0749@1|root,COG1372@1|root,COG0749@2|Bacteria,COG1372@2|Bacteria,1TPTJ@1239|Firmicutes,2487V@186801|Clostridia,22GI8@1570339|Peptoniphilaceae 186801|Clostridia L DNA-directed DNA polymerase - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_73193_2 1158614.I592_02353 2.62e-28 111.0 2DR9Y@1|root,33AUY@2|Bacteria,1VEP1@1239|Firmicutes,4HIWW@91061|Bacilli,4B4BW@81852|Enterococcaceae 91061|Bacilli L NUMOD4 motif - - - - - - - - - - - - HNH_3,NUMOD4 k59_422244_2 631454.N177_0326 1.1e-37 137.0 COG3108@1|root,COG3772@1|root,COG3108@2|Bacteria,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,2U7X4@28211|Alphaproteobacteria 28211|Alphaproteobacteria G lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_97220_1 395019.Bmul_3835 3.35e-09 62.0 COG0338@1|root,COG0338@2|Bacteria,1QZWQ@1224|Proteobacteria 1224|Proteobacteria L DNA N-6-adenine-methyltransferase (Dam) - - - - - - - - - - - - Dam k59_318464_2 1788439.A0A190WHD0_9CIRC 3.07e-08 58.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_464144_1 523791.Kkor_1898 2.5e-34 127.0 COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,1RQ4B@1236|Gammaproteobacteria,1XJ63@135619|Oceanospirillales 135619|Oceanospirillales L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB - 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII k59_142599_1 10228.TriadP52877 1.18e-14 79.7 2D04N@1|root,2SCSW@2759|Eukaryota,3AE35@33154|Opisthokonta 33154|Opisthokonta - - - - - - - - - - - - - - - k59_388242_1 1094553.MCS_01290 1.91e-05 52.8 COG4675@1|root,COG4675@2|Bacteria,1N0FZ@1224|Proteobacteria,2UDXB@28211|Alphaproteobacteria,48T3C@772|Bartonellaceae 28211|Alphaproteobacteria S Phage Tail Collar Domain - - - - - - - - - - - - Collar k59_183921_2 498761.HM1_0053 1.87e-06 54.7 COG1403@1|root,COG1403@2|Bacteria,1V178@1239|Firmicutes,24DE2@186801|Clostridia 186801|Clostridia V HNH endonuclease - - - - - - - - - - - - DUF4373 k59_470831_5 373903.Hore_07940 1.4e-16 84.7 COG0860@1|root,COG5401@1|root,COG0860@2|Bacteria,COG5401@2|Bacteria,1TQ74@1239|Firmicutes,24FT2@186801|Clostridia,3WBP8@53433|Halanaerobiales 186801|Clostridia M Sporulation and spore germination - - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3,Germane k59_202722_1 84531.JMTZ01000032_gene351 1.1e-06 58.9 COG0616@1|root,COG0616@2|Bacteria,1QGPW@1224|Proteobacteria,1RZZW@1236|Gammaproteobacteria,1X588@135614|Xanthomonadales 135614|Xanthomonadales OU Peptidase family S49 - - - - - - - - - - - - Peptidase_S49 k59_265598_1 1128421.JAGA01000004_gene2578 1.46e-13 74.3 COG0706@1|root,COG0706@2|Bacteria,2NP6C@2323|unclassified Bacteria 2|Bacteria U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins yidC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP k59_19138_1 1204521.I7A8M7_9CAUD 3.03e-140 429.0 4QCZC@10239|Viruses,4QX3V@35237|dsDNA viruses no RNA stage,4QRH3@28883|Caudovirales,4QHVR@10662|Myoviridae 10662|Myoviridae S Bacterial DNA polymerase III alpha subunit - - - - - - - - - - - - - k59_388276_1 411473.RUMCAL_02622 6.13e-46 156.0 28J2E@1|root,2Z8YX@2|Bacteria,1TRF9@1239|Firmicutes,249U3@186801|Clostridia,3WHI7@541000|Ruminococcaceae 186801|Clostridia S Protein of unknown function (DUF2815) - - - - - - - - - - - - DUF2815 k59_79444_1 1041138.KB890232_gene6065 3.53e-134 409.0 COG4096@1|root,COG4096@2|Bacteria,1QXJA@1224|Proteobacteria,2TXZ6@28211|Alphaproteobacteria,4BDD2@82115|Rhizobiaceae 28211|Alphaproteobacteria L Type III restriction enzyme, res subunit - - 3.1.21.5 ko:K01156 - - - - ko00000,ko01000,ko02048 - - - ResIII k59_363740_1 391038.Bphy_1919 1.59e-12 70.1 COG2197@1|root,COG2197@2|Bacteria,1NA3X@1224|Proteobacteria,2VWX0@28216|Betaproteobacteria,1KAW7@119060|Burkholderiaceae 28216|Betaproteobacteria KT phage-related functions and prophages - - - - - - - - - - - - HNH_3 k59_305200_2 932678.THERU_07455 3.43e-22 94.0 2FCKR@1|root,344Q1@2|Bacteria 2|Bacteria L DNA methylase - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_471373_5 1079986.JH164865_gene6779 2.25e-22 90.5 arCOG05626@1|root,32V4D@2|Bacteria,2I38M@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_329994_2 76114.ebA5484 1.92e-05 50.8 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,2VP7E@28216|Betaproteobacteria 28216|Betaproteobacteria S portal protein - - - - - - - - - - - - Phage_portal k59_186105_1 1618247.A0A0C5IMK7_9CIRC 7.18e-05 51.6 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_515033_2 1556290.A0A0A0RL96_9CAUD 6.91e-08 62.4 4QGMJ@10239|Viruses,4QSYG@28883|Caudovirales,4QM5B@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_124747_1 1470591.BW41_00472 4.19e-12 71.2 COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,2TRS3@28211|Alphaproteobacteria,2K1CG@204457|Sphingomonadales 204457|Sphingomonadales G Alpha-amylase domain - - 3.2.1.20 ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - GH31 - Alpha-amylase,DUF3459 k59_84084_1 1692249.A0A0K1RLN8_9CIRC 1.75e-18 88.2 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_103977_2 5932.XP_004027344.1 9.35e-26 119.0 COG0086@1|root,KOG0260@2759|Eukaryota,3ZAWJ@5878|Ciliophora 5878|Ciliophora K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates - - 2.7.7.6 ko:K03006 ko00230,ko00240,ko01100,ko03020,ko05016,ko05168,ko05169,map00230,map00240,map01100,map03020,map05016,map05168,map05169 M00180 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5,RNA_pol_Rpb1_6 k59_350270_1 749413.E5DV63_9VIRU 4.7e-09 61.6 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage 10239|Viruses S HNH endonuclease - - - - - - - - - - - - - k59_432325_1 743721.Psesu_1138 1.11e-06 51.6 COG1396@1|root,COG1396@2|Bacteria 2|Bacteria K sequence-specific DNA binding MA20_07360 - - ko:K07075,ko:K15546 - - - - ko00000,ko03000 - - - HTH_3,HTH_31,NTP_transf_2,Peptidase_S24,SKI k59_288774_1 1123302.KB904184_gene1005 1.48e-14 77.4 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,4H9Z7@91061|Bacilli 91061|Bacilli L DNA polymerase polA_2 - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_288774_2 1408424.JHYI01000032_gene3844 3.76e-20 90.5 28J2E@1|root,2Z8YX@2|Bacteria,1TRF9@1239|Firmicutes,4HHVK@91061|Bacilli,1ZEQW@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2815) - - - - - - - - - - - - DUF2815 k59_637974_6 1609634.A0A0C5AFV4_9VIRU 5.41e-83 274.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_515049_3 879308.HMPREF9130_1217 1.2e-25 115.0 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,2487V@186801|Clostridia,22GI8@1570339|Peptoniphilaceae 186801|Clostridia L DNA-directed DNA polymerase - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_432326_1 105154.Q9MBU6_9VIRU 7.6e-150 447.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_596288_2 1692257.A0A0K1RL39_9CIRC 8.17e-97 294.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_576168_1 1692249.A0A0K1RLN8_9CIRC 6.49e-24 102.0 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_227166_2 243233.MCA1971 2.93e-92 289.0 COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,1RNAQ@1236|Gammaproteobacteria,1XDIK@135618|Methylococcales 135618|Methylococcales J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS - 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b k59_145388_1 105154.Q9MBU6_9VIRU 3.68e-85 270.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_22279_2 1095769.CAHF01000022_gene258 1.38e-11 61.6 COG2155@1|root,COG2155@2|Bacteria,1N77I@1224|Proteobacteria,2WC2Z@28216|Betaproteobacteria,4752Q@75682|Oxalobacteraceae 28216|Betaproteobacteria S Domain of unknown function (DUF378) - - - ko:K09779 - - - - ko00000 - - - DUF378 k59_620611_1 942016.E9NIG5_9CAUD 2.57e-67 233.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_478596_2 1120936.KB907208_gene1116 2.89e-07 54.7 2FA48@1|root,342D2@2|Bacteria,2H6VX@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_251718_2 476272.RUMHYD_01755 0.000375 50.1 COG3860@1|root,COG3860@2|Bacteria,1UBEF@1239|Firmicutes,258T3@186801|Clostridia,3Y212@572511|Blautia 2|Bacteria L GIY-YIG type nucleases (URI domain) - - - - - - - - - - - - DUF2087,GIY-YIG,HTH_20,NUMOD3 k59_519098_3 504487.JCM19302_4005 3.4e-34 132.0 COG3298@1|root,COG3298@2|Bacteria,4NECH@976|Bacteroidetes,1HY85@117743|Flavobacteriia 976|Bacteroidetes L 3'-5' exonuclease related to the exonuclease domain of PolB - - - ko:K07501 - - - - ko00000 - - - DNA_pol_B_exo2 k59_579236_2 4641.GSMUA_Achr2P12740_001 1.53e-06 52.8 COG1403@1|root,2QQI3@2759|Eukaryota,37PXC@33090|Viridiplantae,3GEP1@35493|Streptophyta,3KMTV@4447|Liliopsida 35493|Streptophyta V HNH endonuclease - - - - - - - - - - - - HNH_5 k59_558599_1 1041159.AZUW01000007_gene4989 2.62e-25 109.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2TSDW@28211|Alphaproteobacteria,4BCQ8@82115|Rhizobiaceae 28211|Alphaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_374589_2 428125.CLOLEP_01413 2.8e-37 128.0 2E2Y0@1|root,32XYV@2|Bacteria,1VD9S@1239|Firmicutes,24PK0@186801|Clostridia,3WPDR@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_230348_1 1408428.JNJP01000003_gene3493 2.54e-58 189.0 COG0270@1|root,COG0270@2|Bacteria 2|Bacteria L DNA (cytosine-5-)-methyltransferase activity - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_579499_2 1618251.A0A0C5I2L8_9CIRC 3.33e-08 63.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_271873_2 1609634.A0A0C5AFV4_9VIRU 1.45e-62 213.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_174849_1 1165094.RINTHH_3920 1.51e-38 142.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_256427_1 1123248.KB893370_gene4948 1.47e-35 140.0 COG0474@1|root,COG0474@2|Bacteria,4NERM@976|Bacteroidetes,1IR88@117747|Sphingobacteriia 976|Bacteroidetes P TIGRFAM ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter yoaB - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 k59_649231_2 1121091.AUMP01000017_gene897 1.27e-10 65.1 COG0451@1|root,COG0451@2|Bacteria,1V34Y@1239|Firmicutes,4HCJE@91061|Bacilli 91061|Bacilli M epimerase dehydratase - - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GAF_3,GDP_Man_Dehyd k59_212686_1 620914.JH621251_gene2331 2.14e-66 228.0 COG2273@1|root,COG3401@1|root,COG2273@2|Bacteria,COG3401@2|Bacteria,4PNM1@976|Bacteroidetes,1IK8V@117743|Flavobacteriia 976|Bacteroidetes G Hydrolase Family 16 - - - - - - - - - - - - - k59_340523_1 1234888.K0A2J2_9VIRU 6.75e-65 216.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_563200_2 1429767.W6B178_9CAUD 1.31e-49 170.0 4QCUB@10239|Viruses,4QYNV@35237|dsDNA viruses no RNA stage,4QRVM@28883|Caudovirales,4QNUK@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_316319_1 49964.Q94MS4_9CAUD 1.77e-11 65.9 4QCUF@10239|Viruses,4QV7U@35237|dsDNA viruses no RNA stage,4QQ89@28883|Caudovirales,4QNCY@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_234632_1 1589297.A0A0B5H2K0_9CAUD 1.49e-31 119.0 4QFIS@10239|Viruses,4QSG1@28883|Caudovirales,4QP3U@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_297239_1 1120958.AULD01000005_gene1807 0.00015 49.7 COG1403@1|root,COG1403@2|Bacteria,2GTWN@201174|Actinobacteria 201174|Actinobacteria V Pfam HNH endonuclease - - - - - - - - - - - - HNH k59_256468_1 1234888.K0A2J2_9VIRU 9e-32 127.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_552956_1 1555202.A0A097EX05_9CAUD 1.55e-13 80.5 4QBY0@10239|Viruses,4QQ4Q@28883|Caudovirales,4QIYE@10662|Myoviridae 10662|Myoviridae S AAA domain - - - - - - - - - - - - - k59_180817_3 1112217.PPL19_05125 1.82e-13 76.6 COG5185@1|root,COG5185@2|Bacteria,1QV8Y@1224|Proteobacteria,1T2AE@1236|Gammaproteobacteria 1236|Gammaproteobacteria D tail protein - - - - - - - - - - - - TMP_2,Tape_meas_lam_C k59_492001_1 1120985.AUMI01000001_gene2164 7.59e-08 61.2 COG5281@1|root,COG5281@2|Bacteria,1TPWF@1239|Firmicutes,4H3NF@909932|Negativicutes 909932|Negativicutes S tape measure - - - - - - - - - - - - - k59_199457_1 977880.RALTA_B0417 1.14e-22 101.0 COG5164@1|root,COG5164@2|Bacteria,1N2ZN@1224|Proteobacteria,2W0KB@28216|Betaproteobacteria,1KCZE@119060|Burkholderiaceae 28216|Betaproteobacteria K regulation of DNA-templated transcription, elongation - - - - - - - - - - - - - k59_15850_1 428125.CLOLEP_01409 1.44e-59 199.0 COG4626@1|root,COG4626@2|Bacteria,1TT9I@1239|Firmicutes,24AFK@186801|Clostridia,3WNF4@541000|Ruminococcaceae 186801|Clostridia S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_239207_1 159749.K0SC59 4.52e-08 60.1 KOG1546@1|root,KOG1546@2759|Eukaryota,2XB63@2836|Bacillariophyta 2836|Bacillariophyta DO Caspase domain - - - - - - - - - - - - Peptidase_C14 k59_347017_1 298653.Franean1_6734 2.62e-14 75.5 COG0714@1|root,COG0714@2|Bacteria,2GWNF@201174|Actinobacteria,4EWUX@85013|Frankiales 201174|Actinobacteria S AAA domain (dynein-related subfamily) - - - - - - - - - - - - AAA_5 k59_655863_1 1692242.A0A0K1RL37_9CIRC 2.59e-17 84.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_655863_2 1788454.A0A190WHE4_9CIRC 3.31e-31 119.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_361509_1 929562.Emtol_1428 6.35e-10 64.7 COG1403@1|root,COG1403@2|Bacteria,4NJ0T@976|Bacteroidetes,47MEF@768503|Cytophagia 976|Bacteroidetes L HNH endonuclease - - - - - - - - - - - - HNH,HNH_5 k59_140133_1 172088.AUGA01000071_gene7569 5.13e-34 132.0 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,2U6BJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S TIGRFAM phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_302711_2 326427.Cagg_3641 1.17e-11 66.6 COG1200@1|root,COG1200@2|Bacteria,2G5YM@200795|Chloroflexi,3753C@32061|Chloroflexia 32061|Chloroflexia L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge k59_322182_1 416591.Tlet_0026 8.39e-08 58.9 COG4974@1|root,COG4974@2|Bacteria 2|Bacteria L Belongs to the 'phage' integrase family xerC_2 - - ko:K03733,ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_5,Phage_integrase k59_404714_3 445970.ALIPUT_01661 3.83e-122 365.0 2DBFR@1|root,2Z8ZR@2|Bacteria,4NG43@976|Bacteroidetes,2G0C1@200643|Bacteroidia 976|Bacteroidetes S Phage terminase large subunit - - - - - - - - - - - - Terminase_3,Terminase_6 k59_102131_1 1618242.A0A0C5IBR9_9CIRC 9.76e-29 118.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_610172_1 106648.BBLJ01000034_gene2596 7.96e-64 211.0 COG0582@1|root,COG0582@2|Bacteria,1NWGS@1224|Proteobacteria,1S5J8@1236|Gammaproteobacteria,3NM1I@468|Moraxellaceae 1236|Gammaproteobacteria L Phage integrase family - - - - - - - - - - - - Phage_integrase k59_390310_2 1038860.AXAP01000015_gene2006 3.05e-41 154.0 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,2U6BJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S TIGRFAM phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_349228_6 910314.HMPREF9220_0608 3.73e-07 65.5 COG4733@1|root,COG4733@2|Bacteria,1TSG2@1239|Firmicutes,4H2UE@909932|Negativicutes 909932|Negativicutes S cellulase activity - - - - - - - - - - - - Phage-tail_3 k59_533867_1 2003327.CAPSD_BPCHP 5.68e-26 114.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_431162_2 1120979.ATVB01000007_gene1117 5.08e-25 110.0 28MKK@1|root,2ZAWR@2|Bacteria,2IS2W@201174|Actinobacteria,4D1DD@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - RNA_helicase,Viral_Rep k59_205446_1 358823.DF19_25135 2.82e-41 154.0 COG0305@1|root,COG1066@1|root,COG0305@2|Bacteria,COG1066@2|Bacteria,2I8H0@201174|Actinobacteria 201174|Actinobacteria L AAA domain - - - - - - - - - - - - AAA_25,DnaB k59_308143_2 1353529.M899_2006 1.69e-12 67.0 COG1694@1|root,COG1694@2|Bacteria 2|Bacteria FG Mazg nucleotide pyrophosphohydrolase MA20_27270 - - - - - - - - - - - MazG k59_616011_1 1505225.A0A068CBG2_9CAUD 5.35e-32 120.0 4QBHW@10239|Viruses,4QTT7@28883|Caudovirales,4QJZQ@10662|Myoviridae 10662|Myoviridae S sequence-specific DNA binding transcription factor activity - - - - - - - - - - - - - k59_451926_1 1177181.T9A_00139 9.71e-08 60.5 COG3378@1|root,COG3378@2|Bacteria,1MV7I@1224|Proteobacteria,1RRN5@1236|Gammaproteobacteria,1XQQ9@135619|Oceanospirillales 135619|Oceanospirillales S D5 N terminal like - - - ko:K06919 - - - - ko00000 - - - D5_N k59_616038_1 909663.KI867149_gene3278 1.47e-09 65.9 COG1196@1|root,COG5281@1|root,COG1196@2|Bacteria,COG5281@2|Bacteria,1MX2R@1224|Proteobacteria,42THQ@68525|delta/epsilon subdivisions 1224|Proteobacteria D tape measure protein - - - - - - - - - - - - Phage_HK97_TLTM k59_82848_2 1244869.H261_11074 7.1e-59 228.0 COG4733@1|root,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria,2TV2W@28211|Alphaproteobacteria,2JV2T@204441|Rhodospirillales 204441|Rhodospirillales S COG4733 Phage-related protein, tail component - - - - - - - - - - - - Lambda_tail_I,Phage-tail_3 k59_639864_3 468059.AUHA01000003_gene1672 1.29e-07 57.8 28HY4@1|root,2Z83J@2|Bacteria,4P146@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - k59_495703_2 1168547.L7P648_9CIRC 5.45e-51 178.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_310280_1 329254.Q2NPI6_9CAUD 0.000725 47.4 4QAYV@10239|Viruses,4QUZ7@35237|dsDNA viruses no RNA stage,4QPU3@28883|Caudovirales,4QKKX@10699|Siphoviridae 10699|Siphoviridae S Phage portal protein - - - - - - - - - - - - - k59_207602_1 1566993.A0A1B1FBJ0_9CAUD 6.36e-15 78.2 4QGZV@10239|Viruses,4QT19@28883|Caudovirales 28883|Caudovirales S methyltransferase activity - - - - - - - - - - - - - k59_188062_1 5759.rna_EHI_193630-1 1.2e-23 100.0 2CSEE@1|root,2RBK2@2759|Eukaryota,3X9MH@554915|Amoebozoa 554915|Amoebozoa G RNA helicase - - - - - - - - - - - - RNA_helicase k59_146960_2 1172179.AUKV01000021_gene1819 4.51e-10 70.9 COG0791@1|root,COG3409@1|root,COG0791@2|Bacteria,COG3409@2|Bacteria,2I61A@201174|Actinobacteria 201174|Actinobacteria M Peptidoglycan-binding domain 1 protein - - - - - - - - - - - - NLPC_P60,PG_binding_1 k59_495709_2 504487.JCM19302_682 9.09e-09 59.7 COG1511@1|root,COG5295@1|root,COG1511@2|Bacteria,COG5295@2|Bacteria,4NRM9@976|Bacteroidetes,1I3QV@117743|Flavobacteriia 976|Bacteroidetes UW Hep Hag repeat protein - - - - - - - - - - - - - k59_167474_2 1462526.BN990_04234 2.54e-37 130.0 COG0758@1|root,COG0758@2|Bacteria,1VNFT@1239|Firmicutes,4HZZP@91061|Bacilli 91061|Bacilli LU Protein of unknown function (DUF2493) - - - - - - - - - - - - DUF2493 k59_618965_4 195105.CN97_00740 9.23e-05 54.3 295SR@1|root,2ZT41@2|Bacteria,1RF8D@1224|Proteobacteria,2U701@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_393024_1 1618260.A0A0C5I2C5_9CIRC 7.47e-69 218.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_393025_1 870187.Thini_0674 6.61e-08 62.4 COG4733@1|root,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria 1224|Proteobacteria O Phage-related protein, tail - - - - - - - - - - - - DUF1983,Lambda_tail_I,Phage-tail_3 k59_393316_2 1116482.K9L524_9CAUD 2.34e-11 67.0 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales 28883|Caudovirales S HNH endonuclease - - - - - - - - - - - - - k59_351805_2 1379717.S5SY19_9CIRC 3.21e-26 112.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_4037_1 652103.Rpdx1_3609 5e-10 64.7 COG5281@1|root,COG5281@2|Bacteria,1R47M@1224|Proteobacteria,2TUIV@28211|Alphaproteobacteria,3JY6I@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S COG5281, Phage-related minor tail protein - - - - - - - - - - - - - k59_68392_1 999541.bgla_1g10970 7.79e-12 76.6 COG4733@1|root,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria,2VJEP@28216|Betaproteobacteria,1KBVU@119060|Burkholderiaceae 28216|Betaproteobacteria S Phage-related protein, tail - - - - - - - - - - - - DUF1983,Phage-tail_3 k59_416962_2 360910.BAV0254 0.000269 46.2 COG1396@1|root,COG1396@2|Bacteria,1QU8X@1224|Proteobacteria,2VT1E@28216|Betaproteobacteria 28216|Betaproteobacteria K Transcriptional regulator - - - - - - - - - - - - HTH_3 k59_354701_1 1234888.K0A2J2_9VIRU 4.75e-50 176.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_521731_1 1122201.AUAZ01000017_gene2960 2.92e-74 239.0 COG5362@1|root,COG5362@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Terminase_6C k59_521731_3 1173762.S4TT79_9CAUD 1.12e-71 226.0 4QGM6@10239|Viruses,4QYNV@35237|dsDNA viruses no RNA stage,4QRH4@28883|Caudovirales,4QP0P@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_439415_1 105154.Q9MBU3_9VIRU 1.45e-08 60.8 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_150491_1 318586.Pden_0362 5.64e-11 67.8 COG4653@1|root,COG4653@2|Bacteria,1MYMH@1224|Proteobacteria,2TUSK@28211|Alphaproteobacteria,2PX8N@265|Paracoccus 28211|Alphaproteobacteria S Phage capsid family - - - - - - - - - - - - Phage_capsid k59_294426_3 335283.Neut_1467 0.000923 46.2 2AFXG@1|root,31610@2|Bacteria,1PWPJ@1224|Proteobacteria,2VWSI@28216|Betaproteobacteria,374EY@32003|Nitrosomonadales 28216|Betaproteobacteria S Phage gp6-like head-tail connector protein - - - - - - - - - - - - Phage_connect_1 k59_376421_1 543153.B3VMB9_9CAUD 2.09e-14 82.0 4QAY9@10239|Viruses,4QV7W@35237|dsDNA viruses no RNA stage 10239|Viruses S D5 N terminal like - GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016032,GO:0016070,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0018130,GO:0019058,GO:0019079,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0039693,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044403,GO:0044419,GO:0046483,GO:0051704,GO:0071704,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_191922_1 585503.HMPREF7545_1731 1.62e-21 100.0 COG5323@1|root,COG5323@2|Bacteria,1UMAZ@1239|Firmicutes,4H9ED@909932|Negativicutes 909932|Negativicutes S Terminase-like family - - - - - - - - - - - - Terminase_6 k59_439438_2 935261.JAGL01000009_gene1169 4.73e-18 79.0 2EI4V@1|root,33BW7@2|Bacteria 2|Bacteria S Protein of unknwon function (DUF3310) - - - - - - - - - - - - DUF3310 k59_622922_1 2003327.CAPSD_BPCHP 1.94e-37 139.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_622922_3 145579.B_BPPHM 7.73e-15 73.9 4QDBB@10239|Viruses,4QUM0@29258|ssDNA viruses,4QP4D@10841|Microviridae 10841|Microviridae S Chlamydia-phage Chp2 scaffold (Chlamy_scaf) - - - - - - - - - - - - - k59_90469_2 1500281.JQKZ01000001_gene1242 2.08e-05 47.8 COG3409@1|root,COG3409@2|Bacteria,4NFKN@976|Bacteroidetes,1HWSX@117743|Flavobacteriia,3ZRFD@59732|Chryseobacterium 976|Bacteroidetes M N-acetylmuramidase - - - - - - - - - - - - Muraidase,PG_binding_1 k59_27377_2 674081.D4N3W8_9CAUD 4.09e-26 103.0 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales 28883|Caudovirales S HNH endonuclease - - - - - - - - - - - - - k59_7906_2 1485543.JMME01000020_gene773 2.11e-18 92.0 COG1196@1|root,COG4123@1|root,COG1196@2|Bacteria,COG4123@2|Bacteria 2|Bacteria AJ Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) - - 2.1.1.255 ko:K16217 - - - - ko00000,ko01000 - - - DUF4349,Dimerisation2,Methyltransf_2 k59_547577_1 1618247.A0A0C5IMK7_9CIRC 7.24e-07 53.9 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_235762_1 1288079.AUKN01000040_gene1500 1.17e-48 174.0 COG1372@1|root,COG1372@2|Bacteria,2IABP@201174|Actinobacteria 201174|Actinobacteria L Participates in initiation and elongation during chromosome replication - - - - - - - - - - - - - k59_96130_1 457570.Nther_2910 5.84e-40 148.0 COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia 186801|Clostridia L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_564449_4 1692252.A0A0K1RL35_9CIRC 2.67e-86 268.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_503083_1 1609634.A0A0C5ANA6_9VIRU 1.44e-09 64.3 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_135708_3 1161902.HMPREF0378_1178 2.44e-30 114.0 COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,24HF0@186801|Clostridia,3WDAY@538999|Clostridiales incertae sedis 186801|Clostridia F MafB19-like deaminase comEB - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 k59_342914_3 57477.J9PLM0_9CAUD 6.23e-22 94.0 4QB9C@10239|Viruses,4QWED@35237|dsDNA viruses no RNA stage,4QTNA@28883|Caudovirales,4QJHN@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_627510_2 1408311.JNJM01000040_gene946 7.8e-10 61.6 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,2PRYV@265975|Oribacterium 186801|Clostridia L SNF2 family N-terminal domain - - - - - - - - - - - - SNF2_N k59_348180_1 1121481.AUAS01000004_gene1712 0.0 1123.0 COG0553@1|root,COG0863@1|root,COG0553@2|Bacteria,COG0863@2|Bacteria,4NHHF@976|Bacteroidetes,47S0J@768503|Cytophagia 976|Bacteroidetes L DNA methylase - - - - - - - - - - - - Helicase_C,N6_N4_Mtase,SNF2_N k59_348180_2 1327990.S0A3B9_9CAUD 6.22e-25 99.4 4QC5A@10239|Viruses,4QX98@35237|dsDNA viruses no RNA stage,4QRV3@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_348180_6 40523.A8AT12_BPA51 8.85e-57 186.0 4QHN9@10239|Viruses,4QX1H@35237|dsDNA viruses no RNA stage,4QU3Z@28883|Caudovirales,4QJE6@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_348186_1 926569.ANT_24370 1.75e-20 84.3 arCOG13021@1|root,33BFU@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_322582_1 589865.DaAHT2_2366 1.99e-19 95.5 COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,42MKZ@68525|delta/epsilon subdivisions,2WING@28221|Deltaproteobacteria,2MIYB@213118|Desulfobacterales 28221|Deltaproteobacteria F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) queC - 6.3.4.20 ko:K06920 ko00790,ko01100,map00790,map01100 - R09978 RC00959 ko00000,ko00001,ko01000,ko03016 - - iAF987.Gmet_3075 QueC k59_450880_1 1111454.HMPREF1250_1035 6.09e-31 121.0 COG0553@1|root,COG0553@2|Bacteria,1TP2C@1239|Firmicutes,4H2V4@909932|Negativicutes 909932|Negativicutes KL DEAD-like helicases superfamily - - - - - - - - - - - - N6_N4_Mtase k59_35944_2 649349.Lbys_1835 3.97e-07 58.9 COG3023@1|root,COG3023@2|Bacteria,4NE38@976|Bacteroidetes,47SI1@768503|Cytophagia 976|Bacteroidetes V Negative regulator of beta-lactamase expression amiD - 3.5.1.28 ko:K01447,ko:K11066 - - R04112 RC00064,RC00141 ko00000,ko01000,ko01011 - - - Amidase_2,PG_binding_1 k59_468593_2 1692257.A0A0K1RL39_9CIRC 1.45e-08 62.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_35966_1 1234888.K0A2J2_9VIRU 1.29e-43 157.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_16899_1 1172188.KB911820_gene2862 4.01e-13 82.4 COG4675@1|root,COG4675@2|Bacteria 2|Bacteria M tail collar domain protein - - - - - - - - - - - - Collar k59_240278_1 1618251.A0A0C5I2L8_9CIRC 3.71e-37 141.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_468597_1 33876.JNXY01000004_gene1766 6.6e-14 66.6 2CHCE@1|root,325FJ@2|Bacteria,2HAM1@201174|Actinobacteria 201174|Actinobacteria S Transmembrane Fragile-X-F protein - - - - - - - - - - - - Tmemb_185A k59_468597_3 641112.ACOK01000096_gene946 2e-14 80.9 COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,247SF@186801|Clostridia,3WGST@541000|Ruminococcaceae 186801|Clostridia L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA - - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA k59_348244_1 243164.DET0071 7.51e-35 136.0 COG0553@1|root,COG0553@2|Bacteria,2G7XH@200795|Chloroflexi 200795|Chloroflexi KL SNF2 family N-terminal domain - - 2.7.11.1 ko:K08282 - - - - ko00000,ko01000 - - - Helicase_C,SNF2_N,SNF2_assoc k59_405146_1 1609634.A0A0C5AFV4_9VIRU 3.33e-30 123.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_53998_2 1416009.V9VCX5_9CAUD 2.56e-54 184.0 4QEG2@10239|Viruses,4QVSD@35237|dsDNA viruses no RNA stage,4QRJ9@28883|Caudovirales,4QP0R@10744|Podoviridae 10744|Podoviridae S exonuclease activity - - - - - - - - - - - - - k59_589904_1 529818.AMSG_09577T0 5.16e-16 76.3 2E0C0@1|root,2S7SW@2759|Eukaryota 2759|Eukaryota - - - - - - - - - - - - - - - k59_247151_1 1121285.AUFK01000002_gene9 1.59e-132 411.0 COG1196@1|root,COG1196@2|Bacteria,4PFK2@976|Bacteroidetes,1I7AN@117743|Flavobacteriia 976|Bacteroidetes D nuclear chromosome segregation - - - - - - - - - - - - AAA_23 k59_247151_2 86416.Clopa_2514 6.38e-54 185.0 COG3723@1|root,COG3723@2|Bacteria,1V4M6@1239|Firmicutes,24CV2@186801|Clostridia,36GFQ@31979|Clostridiaceae 186801|Clostridia L Recombinational DNA repair protein (RecE pathway) - - - ko:K07455 - - - - ko00000,ko03400 - - - RecT k59_534017_1 1234888.K0A2J2_9VIRU 7.79e-39 146.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_164747_2 1449347.JQLN01000005_gene4625 2.47e-92 294.0 COG1215@1|root,COG1215@2|Bacteria,2I1T0@201174|Actinobacteria,2M5A6@2063|Kitasatospora 201174|Actinobacteria M Glycosyl transferase family 21 - - 2.4.1.212 ko:K00752 - - - - ko00000,ko01000,ko01003,ko02000 4.D.1.1.10,4.D.1.1.4,4.D.1.1.5 GT2 - - k59_636680_1 693986.MOC_3610 1.8e-12 76.6 COG4643@1|root,COG5545@1|root,COG4643@2|Bacteria,COG5545@2|Bacteria,1QZ04@1224|Proteobacteria,2TY2W@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DNA primase activity - - - - - - - - - - - - - k59_410982_1 1692255.A0A0K1RL52_9CIRC 2.28e-88 273.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_287866_1 1548905.A0A0A1IUL8_9CAUD 6.69e-35 131.0 4QBA2@10239|Viruses,4QPPI@28883|Caudovirales,4QM0B@10699|Siphoviridae 10699|Siphoviridae S Thymidylate synthase - GO:0003674,GO:0003824,GO:0004799,GO:0008150,GO:0008152,GO:0008168,GO:0016740,GO:0016741,GO:0032259,GO:0042083 - - - - - - - - - - - k59_636693_1 1692261.A0A0K1RLL5_9CIRC 1.42e-20 97.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_369842_1 1041930.Mtc_1693 4.52e-05 55.5 COG1520@1|root,COG3291@1|root,arCOG02421@1|root,arCOG02483@1|root,arCOG03550@1|root,arCOG03557@1|root,arCOG02421@2157|Archaea,arCOG02482@2157|Archaea,arCOG02483@2157|Archaea,arCOG02510@2157|Archaea,arCOG03550@2157|Archaea,arCOG03557@2157|Archaea,2Y7RP@28890|Euryarchaeota,2NBKZ@224756|Methanomicrobia 224756|Methanomicrobia S Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - - - - - - - - - - CARDB,DUF3344,PKD k59_369842_2 1107311.Q767_15695 5.69e-06 58.5 COG2304@1|root,COG3291@1|root,COG2304@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1IJ8A@117743|Flavobacteriia,2P0KQ@237|Flavobacterium 976|Bacteroidetes M Pkd domain containing protein - - - - - - - - - - - - CHU_C,Gal_Lectin,HYR,Laminin_G_3,PKD,SprB,TSP_3 k59_82979_2 1618257.A0A0C5IBI9_9CIRC 6.69e-27 113.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_493060_1 691965.D4P7D6_9CAUD 2.31e-79 260.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_513753_1 757424.Hsero_1015 6.12e-05 46.6 2DQWR@1|root,33947@2|Bacteria,1N73Y@1224|Proteobacteria,2W5G7@28216|Betaproteobacteria,478A7@75682|Oxalobacteraceae 28216|Betaproteobacteria S PEP-CTERM motif - - - - - - - - - - - - VPEP k59_534045_1 755731.Clo1100_1151 1.74e-05 49.7 COG1694@1|root,COG1694@2|Bacteria 2|Bacteria FG Mazg nucleotide pyrophosphohydrolase - - - - - - - - - - - - - k59_431285_1 1121447.JONL01000012_gene3405 8.23e-35 142.0 COG0503@1|root,COG2518@1|root,COG0503@2|Bacteria,COG2518@2|Bacteria 2|Bacteria O Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins apt - 2.1.1.163,2.1.1.201,2.1.1.77,2.4.2.7 ko:K00573,ko:K00759,ko:K03183,ko:K07003 ko00130,ko00230,ko01100,ko01110,map00130,map00230,map01100,map01110 M00116,M00117 R00190,R01229,R04378,R04990,R04993,R06859,R08774,R09736 RC00003,RC00063,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000,ko04147 - - - DUF3560,Methyltransf_21,Pribosyltran k59_410997_1 994573.T472_0214080 1.39e-17 92.0 COG4626@1|root,COG4626@2|Bacteria,1TPU1@1239|Firmicutes,248RI@186801|Clostridia,36E5Y@31979|Clostridiaceae 186801|Clostridia S Terminase - - - - - - - - - - - - Terminase_1 k59_410997_2 1144325.PMI22_05747 5.15e-25 112.0 28KTY@1|root,2ZAAW@2|Bacteria,1R81A@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_411397_1 575586.HMPREF0016_00841 5.16e-41 142.0 COG3772@1|root,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,1S99W@1236|Gammaproteobacteria,3NKTC@468|Moraxellaceae 1236|Gammaproteobacteria G Phage lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_185896_1 1234888.K0A2J2_9VIRU 1.83e-40 148.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_473289_1 546414.Deide_01610 1.92e-28 118.0 COG2812@1|root,COG2812@2|Bacteria,1WJ27@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX - 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3 k59_497450_5 1469557.JSWF01000036_gene808 4.28e-13 78.6 COG3209@1|root,COG3291@1|root,COG3897@1|root,COG4886@1|root,COG5306@1|root,COG5492@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3897@2|Bacteria,COG4886@2|Bacteria,COG5306@2|Bacteria,COG5492@2|Bacteria 2|Bacteria N domain, Protein htaA - 3.4.21.72 ko:K01347,ko:K03561,ko:K12287 - - - - ko00000,ko01000,ko01002,ko02000,ko02044 1.A.30.2.1,1.B.12.3 - - CHU_C,DUF2341,HtaA,LRR_5,Laminin_G_3,MotA_ExbB k59_436944_1 1173762.S4TP28_9CAUD 1.93e-54 191.0 4QGA5@10239|Viruses,4QURD@35237|dsDNA viruses no RNA stage,4QT9N@28883|Caudovirales,4QP47@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_519032_3 1121382.JQKG01000001_gene2517 5.69e-52 188.0 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria 2|Bacteria K chromosome segregation terL - - - - - - - - - - - Terminase_6,Terminase_6C k59_539603_1 388051.AUFE01000035_gene4020 1.02e-63 209.0 COG4653@1|root,COG4653@2|Bacteria 2|Bacteria G Phage capsid family - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_25716_2 984262.SGRA_1080 1.19e-65 209.0 COG0602@1|root,COG0602@2|Bacteria 2|Bacteria H queuosine metabolic process queE GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008144,GO:0016829,GO:0016840,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:1901681,GO:1904047 1.97.1.4,4.3.99.3 ko:K04068,ko:K10026 ko00790,ko01100,map00790,map01100 - R04710,R10002 RC02989 ko00000,ko00001,ko01000,ko03016 - - - Fer4_12,Fer4_14,Radical_SAM k59_600188_1 1122201.AUAZ01000017_gene2949 6.55e-63 212.0 COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,1RXX2@1236|Gammaproteobacteria,46B9P@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative metallopeptidase domain - - - - - - - - - - - - DUF2201,DUF2201_N k59_374664_1 1457250.BBMO01000002_gene2316 0.0001 53.1 arCOG00373@1|root,arCOG00373@2157|Archaea 2157|Archaea - - - - - - - - - - - - - - - k59_540192_2 643473.KB235930_gene3744 6.18e-59 196.0 COG0343@1|root,COG0343@2|Bacteria,1GAUU@1117|Cyanobacteria,1HS8U@1161|Nostocales 1117|Cyanobacteria J queuine tRNA-ribosyltransferase activity - - - - - - - - - - - - TGT k59_457481_1 490913.C4NT91_9CAUD 1.93e-22 95.9 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales,4QNBQ@10744|Podoviridae 10744|Podoviridae S HNH endonuclease - - - - - - - - - - - - - k59_540212_1 1420600.W5RNT1_9CIRC 1.18e-25 107.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_540212_2 1618237.A0A0C5IMG6_9CIRC 4.5e-34 127.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_374695_1 338966.Ppro_2579 0.000202 48.9 2ANJH@1|root,31DIJ@2|Bacteria,1P4XW@1224|Proteobacteria 1224|Proteobacteria S PEP-CTERM motif - - - - - - - - - - - - VPEP k59_106819_1 1187128.I2GUC6_9CAUD 4.01e-38 138.0 4QBHW@10239|Viruses,4QW8N@35237|dsDNA viruses no RNA stage,4QTT7@28883|Caudovirales,4QJZQ@10662|Myoviridae 10662|Myoviridae S sequence-specific DNA binding transcription factor activity - - - - - - - - - - - - - k59_479356_1 1029823.AFIE01000021_gene3181 6.15e-17 80.9 2DIG9@1|root,3036R@2|Bacteria,1R0G3@1224|Proteobacteria,1T4GR@1236|Gammaproteobacteria,3NMR1@468|Moraxellaceae 1236|Gammaproteobacteria L YqaJ-like viral recombinase domain - - - - - - - - - - - - YqaJ k59_25764_1 291607.MREP_SCSVF 3.57e-21 95.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_519774_1 445970.ALIPUT_01194 0.00067 42.0 2E8S0@1|root,3332X@2|Bacteria,4NWIA@976|Bacteroidetes,2FUQI@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_519774_2 1123058.KB894219_gene152 3.37e-38 142.0 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,4NN30@976|Bacteroidetes 976|Bacteroidetes S Psort location Cytoplasmic, score 8.96 - - - - - - - - - - - - Terminase_6,Terminase_6C k59_643091_3 1120945.ATUW01000003_gene99 5.43e-51 192.0 COG1061@1|root,COG1061@2|Bacteria,2GIU5@201174|Actinobacteria,4D3RX@85005|Actinomycetales 201174|Actinobacteria L Type III restriction enzyme, res subunit sdrA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - ResIII k59_525129_1 1234888.K0A2J2_9VIRU 4.55e-81 260.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_174644_2 1463934.JOCF01000062_gene4346 8.57e-15 82.0 COG1475@1|root,COG1475@2|Bacteria,2IAY7@201174|Actinobacteria 201174|Actinobacteria K Belongs to the glycosyl hydrolase 43 family - - - - - - - - - - - - ParBc k59_49111_1 105154.Q9MBU3_9VIRU 1.47e-06 55.1 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_256235_2 222534.KB893767_gene4796 1.46e-32 132.0 COG1061@1|root,COG1061@2|Bacteria,2GIU5@201174|Actinobacteria,4ERPY@85013|Frankiales 201174|Actinobacteria L PFAM type III restriction protein res subunit - - - - - - - - - - - - Helicase_C,ResIII k59_93696_1 1476391.X5KCE1_9CAUD 3.73e-97 306.0 4QF3C@10239|Viruses,4QWIA@35237|dsDNA viruses no RNA stage,4QU4U@28883|Caudovirales,4QNNQ@10744|Podoviridae 10744|Podoviridae S host cell wall - - - - - - - - - - - - - k59_340191_2 35344.A0A097PAT0_BPT12 8.66e-15 85.5 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QP39@10744|Podoviridae 10744|Podoviridae S N-acetylmuramoyl-L-alanine amidase activity - - - - - - - - - - - - - k59_194354_1 1618248.A0A0C5IB82_9CIRC 2.59e-10 60.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_297026_1 691965.D4P7B9_9CAUD 4.06e-32 116.0 4QFDH@10239|Viruses,4QWV5@35237|dsDNA viruses no RNA stage,4QPB8@28883|Caudovirales,4QKNN@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_213117_1 1121372.AULK01000004_gene1151 1.37e-21 101.0 COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,2GJPX@201174|Actinobacteria,4FM3I@85023|Microbacteriaceae 201174|Actinobacteria L DNA polymerase Ligase (LigD) ligD GO:0000166,GO:0000287,GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0003896,GO:0003899,GO:0003909,GO:0003910,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0004652,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006269,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016874,GO:0016886,GO:0016895,GO:0017076,GO:0018130,GO:0019438,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0033554,GO:0034061,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0070566,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0097747,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 ko:K01971,ko:K10747 ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450 - R00381,R00382,R10822,R10823 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - DNA_ligase_A_C,DNA_ligase_A_M,LigD_N k59_420646_1 1618254.A0A0C5IBG4_9CIRC 5.03e-61 196.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_316796_2 371042.NG99_23680 2.75e-88 276.0 COG2189@1|root,COG2189@2|Bacteria,1QUB9@1224|Proteobacteria,1RMSJ@1236|Gammaproteobacteria,3X6F2@551|Erwinia 1236|Gammaproteobacteria L DNA methylase - - 2.1.1.72 ko:K07319 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_626136_1 1122201.AUAZ01000017_gene2960 3.59e-242 680.0 COG5362@1|root,COG5362@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Terminase_6C k59_626136_2 1051675.G0YQI9_9CAUD 5.92e-38 139.0 4QF0B@10239|Viruses,4QX8P@35237|dsDNA viruses no RNA stage,4QSJT@28883|Caudovirales,4QNNK@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_492078_2 1234888.K0A2J2_9VIRU 2.57e-76 250.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_34940_1 883103.HMPREF9703_00522 3.31e-24 99.8 COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,4HH8I@91061|Bacilli,27GDC@186828|Carnobacteriaceae 91061|Bacilli L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_347859_1 1429759.W0LJ63_9CAUD 4.27e-08 62.8 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QKNE@10699|Siphoviridae 10699|Siphoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_281423_1 1042209.HK44_008035 1.27e-28 112.0 COG1041@1|root,COG1041@2|Bacteria,1QWHX@1224|Proteobacteria,1T2VC@1236|Gammaproteobacteria 1236|Gammaproteobacteria L tRNA (guanine-N2-)-methyltransferase activity - - - - - - - - - - - - - k59_347880_1 1034115.G1D5L0_9CAUD 1.1e-39 144.0 4QCF5@10239|Viruses,4QV2A@35237|dsDNA viruses no RNA stage,4QPJI@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_76892_1 196162.Noca_4570 4.59e-46 157.0 COG0518@1|root,COG0518@2|Bacteria,2GKS1@201174|Actinobacteria,4DU8K@85009|Propionibacteriales 201174|Actinobacteria F Glutamine amidotransferase class-I guaA_2 - 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase k59_181779_2 1158606.I579_02487 2.09e-10 67.8 COG0583@1|root,COG0583@2|Bacteria,1TSNI@1239|Firmicutes,4HDGS@91061|Bacilli,4B6UU@81852|Enterococcaceae 91061|Bacilli K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k59_568497_1 981336.F944_01665 6.88e-22 99.8 29XS2@1|root,30JHV@2|Bacteria,1Q0E2@1224|Proteobacteria,1THI7@1236|Gammaproteobacteria,3NQ98@468|Moraxellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_302835_1 768679.TTX_0291 7.27e-15 77.8 COG0602@1|root,arCOG02173@2157|Archaea,2XQYY@28889|Crenarchaeota 28889|Crenarchaeota H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds queE - 4.3.99.3 ko:K10026 ko00790,ko01100,map00790,map01100 - R10002 RC02989 ko00000,ko00001,ko01000,ko03016 - - - Fer4_14,Radical_SAM k59_507337_1 1618248.A0A0C5IB82_9CIRC 3.57e-51 177.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_568513_1 1385658.U5KPZ6_9VIRU 1.1e-215 614.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_568513_2 1609634.A0A0C5ANA6_9VIRU 2.75e-06 54.7 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_610326_1 665956.HMPREF1032_00686 6.55e-11 73.6 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia,3WN92@541000|Ruminococcaceae 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_102326_1 1175654.A0A0S0MVN0_9CAUD 2.64e-27 112.0 4QFED@10239|Viruses,4R072@35237|dsDNA viruses no RNA stage,4QPEH@28883|Caudovirales,4QN2V@10699|Siphoviridae 10699|Siphoviridae S tRNA modification - - - - - - - - - - - - - k59_53724_1 1249480.B649_00010 0.000231 48.9 COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,42NQW@68525|delta/epsilon subdivisions,2YM9J@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 k59_200241_1 1168289.AJKI01000018_gene1989 3e-07 57.8 COG4974@1|root,COG4974@2|Bacteria,4NGE1@976|Bacteroidetes,2FN75@200643|Bacteroidia,3XM1K@558415|Marinilabiliaceae 976|Bacteroidetes L Phage integrase, N-terminal SAM-like domain - - - - - - - - - - - - Phage_int_SAM_4,Phage_integrase k59_206603_1 411460.RUMTOR_00791 1.9e-05 48.1 COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,24XIM@186801|Clostridia,3Y0YK@572511|Blautia 186801|Clostridia K Sigma-70 factor, region 1.2 - - - - - - - - - - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 k59_391981_1 1692253.A0A0K1RLM4_9CIRC 1.32e-28 120.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_371269_4 373903.Hore_17090 4.96e-05 44.3 COG1551@1|root,COG1551@2|Bacteria,1VEEF@1239|Firmicutes,24QPD@186801|Clostridia,3WAY7@53433|Halanaerobiales 186801|Clostridia J Could accelerate the degradation of some genes transcripts potentially through selective RNA binding csrA - - ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 - - - ko00000,ko00001,ko03019 - - - CsrA k59_371269_6 1121033.AUCF01000004_gene5049 1.02e-34 130.0 COG3206@1|root,COG3206@2|Bacteria,1ND5H@1224|Proteobacteria,2UIQZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria M protein involved in exopolysaccharide biosynthesis - - - - - - - - - - - - - k59_371269_8 511437.Lbuc_1540 1.51e-26 119.0 COG1061@1|root,COG1061@2|Bacteria,1TQ62@1239|Firmicutes,4HAJ1@91061|Bacilli,3F3YQ@33958|Lactobacillaceae 91061|Bacilli L Helicase C-terminal domain protein - - - - - - - - - - - - Helicase_C,ResIII k59_432807_1 234267.Acid_6035 2.14e-06 51.6 COG1403@1|root,COG1403@2|Bacteria 2|Bacteria V endonuclease activity - - - - - - - - - - - - HNH k59_432807_2 1476391.X5L4Q2_9CAUD 2.61e-10 60.8 4QEFX@10239|Viruses,4QYYG@35237|dsDNA viruses no RNA stage,4QRRV@28883|Caudovirales,4QNTK@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_84509_1 2003327.CAPSD_BPCHP 1.06e-18 94.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_186986_1 1234888.K0A2J2_9VIRU 1.34e-71 234.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_2436_1 931626.Awo_c35200 1.86e-40 148.0 COG0270@1|root,COG0270@2|Bacteria,1TPNE@1239|Firmicutes,24B1A@186801|Clostridia,25WDZ@186806|Eubacteriaceae 186801|Clostridia H C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_350701_1 942016.E9NIH0_9CAUD 1.08e-51 183.0 4QGA5@10239|Viruses,4QURD@35237|dsDNA viruses no RNA stage,4QT9N@28883|Caudovirales,4QP47@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_229584_1 110365.A0A023AX31 9.73e-11 63.2 2EWQP@1|root,2SYH6@2759|Eukaryota 2759|Eukaryota S RNA helicase - - - - - - - - - - - - RNA_helicase,Viral_Rep k59_599075_1 1537917.JU82_06570 3.4e-56 182.0 2CGG9@1|root,2ZVSJ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_24813_1 1468411.X2KSP8_9CAUD 1.53e-21 94.0 4QDKA@10239|Viruses,4QUPP@35237|dsDNA viruses no RNA stage,4QPPG@28883|Caudovirales,4QMZH@10699|Siphoviridae 10699|Siphoviridae S nuclease activity - - - - - - - - - - - - - k59_5063_1 323848.Nmul_A0661 1.28e-27 109.0 COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,2VH2E@28216|Betaproteobacteria,3721N@32003|Nitrosomonadales 28216|Betaproteobacteria H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids uppS - 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf k59_5063_2 234267.Acid_0903 3.27e-40 142.0 COG0233@1|root,COG0233@2|Bacteria,3Y4AP@57723|Acidobacteria 57723|Acidobacteria J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another frr - - ko:K02838 - - - - ko00000,ko03012 - - - RRF k59_87263_1 1692244.A0A0K1RLR5_9CIRC 3.42e-65 207.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_373501_1 1129192.A0A0E3D9T0_9CAUD 2.78e-09 62.8 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales,4QI6J@10662|Myoviridae 10662|Myoviridae S sequence-specific DNA binding transcription factor activity - - - - - - - - - - - - - k59_251184_3 1399774.JDWH01000001_gene2887 4.24e-31 120.0 28H9R@1|root,2Z7MD@2|Bacteria,1MVTR@1224|Proteobacteria,1RMPH@1236|Gammaproteobacteria,3X3N1@547|Enterobacter 1236|Gammaproteobacteria S Domain of unknown function (DUF932) - - - - - - - - - - - - DUF932 k59_189144_1 322855.Q52PP4_9CAUD 3.95e-07 56.6 4QAUT@10239|Viruses,4QVIM@35237|dsDNA viruses no RNA stage,4QQ7X@28883|Caudovirales 28883|Caudovirales S DNA ligase (ATP) activity - - - - - - - - - - - - - k59_44726_1 1385658.U5KPZ6_9VIRU 1.38e-104 322.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_44726_2 1609634.A0A0C5ANA6_9VIRU 5.04e-09 62.4 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_270983_2 1609634.A0A0C5ANA6_9VIRU 5.13e-12 70.1 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_5085_2 683083.C414_000260173 9.74e-06 48.1 COG1403@1|root,COG1403@2|Bacteria,1ND6I@1224|Proteobacteria,42VUC@68525|delta/epsilon subdivisions,2YQMZ@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria L HNH endonuclease - - - - - - - - - - - - HNH k59_168644_2 105422.BBPM01000003_gene5637 4.48e-07 55.1 COG2730@1|root,COG2730@2|Bacteria,2HW9X@201174|Actinobacteria,2NHP5@228398|Streptacidiphilus 201174|Actinobacteria G CBD_II - - 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 - R06200,R11307,R11308 - ko00000,ko00001,ko01000 - GH5,GH9 - CBM_2,Cellulase k59_641723_3 142661.REP_CACV 1.93e-45 162.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_478398_1 1168034.FH5T_01910 1.44e-35 138.0 COG4974@1|root,COG4974@2|Bacteria,4NX3Q@976|Bacteroidetes,2G3F8@200643|Bacteroidia 976|Bacteroidetes L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_5,Phage_int_SAM_5,Phage_integrase k59_642194_1 1042876.PPS_1220 5.94e-68 221.0 COG0582@1|root,COG0582@2|Bacteria,1QB64@1224|Proteobacteria,1RY8S@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_1,Phage_int_SAM_4,Phage_integrase k59_603164_1 1408311.JNJM01000031_gene2485 7.85e-71 244.0 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,2487V@186801|Clostridia,2PQVX@265975|Oribacterium 186801|Clostridia L DNA polymerase A domain - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_28799_2 596152.DesU5LDRAFT_3375 2.59e-07 59.3 COG4974@1|root,COG4974@2|Bacteria,1RBMG@1224|Proteobacteria,42R21@68525|delta/epsilon subdivisions,2WN4K@28221|Deltaproteobacteria,2M90A@213115|Desulfovibrionales 28221|Deltaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_int_SAM_3,Phage_integrase k59_173719_1 1536772.R70723_06640 9.04e-95 294.0 COG5410@1|root,COG5410@2|Bacteria,1TSMG@1239|Firmicutes,4HBFH@91061|Bacilli,26WBM@186822|Paenibacillaceae 91061|Bacilli S Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C k59_109216_5 6334.EFV52031 2.18e-12 76.3 COG0258@1|root,KOG2519@2759|Eukaryota,38GN8@33154|Opisthokonta,3BAYM@33208|Metazoa,3CX02@33213|Bilateria,40C19@6231|Nematoda 33208|Metazoa L Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double- stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA FEN1 GO:0000287,GO:0000723,GO:0000724,GO:0000725,GO:0000737,GO:0001654,GO:0003008,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004521,GO:0004523,GO:0004527,GO:0004529,GO:0004536,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005730,GO:0005737,GO:0005739,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006302,GO:0006308,GO:0006309,GO:0006310,GO:0006401,GO:0006725,GO:0006807,GO:0006915,GO:0006921,GO:0006950,GO:0006974,GO:0006996,GO:0007049,GO:0007063,GO:0007275,GO:0007423,GO:0007610,GO:0007611,GO:0007613,GO:0008150,GO:0008152,GO:0008219,GO:0008309,GO:0008409,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009987,GO:0010564,GO:0010638,GO:0012501,GO:0016043,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016888,GO:0016891,GO:0016893,GO:0016895,GO:0017108,GO:0019439,GO:0019725,GO:0022402,GO:0022411,GO:0022616,GO:0030145,GO:0030262,GO:0031974,GO:0031981,GO:0032200,GO:0032201,GO:0032501,GO:0032502,GO:0032991,GO:0033043,GO:0033044,GO:0033045,GO:0033260,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0042592,GO:0043010,GO:0043137,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0044786,GO:0045787,GO:0045876,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0048256,GO:0048513,GO:0048518,GO:0048522,GO:0048731,GO:0048856,GO:0050789,GO:0050794,GO:0050877,GO:0050890,GO:0050896,GO:0051128,GO:0051130,GO:0051276,GO:0051716,GO:0051726,GO:0051983,GO:0051984,GO:0060041,GO:0060249,GO:0065007,GO:0065008,GO:0070013,GO:0071704,GO:0071840,GO:0090068,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0097194,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1901576,GO:2001252 - ko:K04799 ko03030,ko03410,ko03450,map03030,map03410,map03450 - - - ko00000,ko00001,ko01000,ko03032,ko03400,ko04147 - - - XPG_I,XPG_N k59_233971_1 942016.E9NIG9_9CAUD 5.09e-10 62.4 4QEG2@10239|Viruses,4QVSD@35237|dsDNA viruses no RNA stage,4QRJ9@28883|Caudovirales,4QP0R@10744|Podoviridae 10744|Podoviridae S exonuclease activity - - - - - - - - - - - - - k59_339767_1 1692246.A0A0K1RLM8_9CIRC 3.33e-19 88.2 4QBFZ@10239|Viruses,4QUKU@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_544812_1 1379719.S5TMX6_9CIRC 2.86e-22 98.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_48837_1 1234888.K0A2J2_9VIRU 1.44e-79 255.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_648441_2 357804.Ping_3459 2.74e-50 180.0 COG2230@1|root,COG3306@1|root,COG2230@2|Bacteria,COG3306@2|Bacteria,1NMM9@1224|Proteobacteria,1T05D@1236|Gammaproteobacteria 1236|Gammaproteobacteria M cyclopropane-fatty-acyl-phospholipid synthase - - - - - - - - - - - - - k59_648441_3 445970.ALIPUT_01612 2.37e-07 52.4 COG0270@1|root,COG0270@2|Bacteria,4NJPP@976|Bacteroidetes,2FKYT@200643|Bacteroidia 976|Bacteroidetes H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_484305_1 679935.Alfi_0779 3.34e-28 110.0 COG3023@1|root,COG3023@2|Bacteria,4PK0G@976|Bacteroidetes,2G1JR@200643|Bacteroidia,22VK1@171550|Rikenellaceae 976|Bacteroidetes V N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - Amidase_2 k59_234002_1 291607.REP6_SCSVF 1.11e-05 54.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_9999_1 1172188.KB911820_gene2876 3.02e-49 180.0 COG0553@1|root,COG0553@2|Bacteria,2GISC@201174|Actinobacteria 201174|Actinobacteria L helicase - - - - - - - - - - - - Helicase_C,SNF2_N k59_93211_1 1051675.G0YQG3_9CAUD 1.58e-53 181.0 4QEG2@10239|Viruses,4QVSD@35237|dsDNA viruses no RNA stage,4QRJ9@28883|Caudovirales,4QP0R@10744|Podoviridae 10744|Podoviridae S exonuclease activity - - - - - - - - - - - - - k59_315751_2 105154.Q9MBU6_9VIRU 2.11e-15 76.3 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_425162_1 1234888.K0A2J2_9VIRU 2.08e-66 220.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_630660_1 497964.CfE428DRAFT_2529 7.01e-17 79.7 2DSBU@1|root,33FEQ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_655826_1 1692249.A0A0K1RL40_9CIRC 1.6e-07 56.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_449318_1 1572715.A0A0A7TWV5_9CAUD 6.52e-20 89.4 4QKM7@10699|Siphoviridae 10699|Siphoviridae S HNH endonuclease - - - - - - - - - - - - - k59_449318_2 1406780.U5PW18_9CAUD 6.16e-10 60.8 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_101187_2 1117108.PAALTS15_09970 2.68e-07 53.9 2EI4V@1|root,33BW7@2|Bacteria,1VKQH@1239|Firmicutes,4HRPN@91061|Bacilli 91061|Bacilli S Protein of unknwon function (DUF3310) - - - - - - - - - - - - DUF3310 k59_655828_1 1692255.A0A0K1RL52_9CIRC 1.19e-13 70.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_655828_3 1692252.A0A0K1RL35_9CIRC 4.94e-73 232.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_216651_1 2711.XP_006468363.1 2.38e-28 120.0 28HK1@1|root,2QPXS@2759|Eukaryota,37NXW@33090|Viridiplantae,3GF00@35493|Streptophyta 35493|Streptophyta L Twinkle homolog protein chloroplastic - GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003697,GO:0003824,GO:0003896,GO:0003899,GO:0004003,GO:0004386,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016043,GO:0016070,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032392,GO:0032508,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051276,GO:0055086,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090407,GO:0097159,GO:0097747,GO:0140097,GO:0140098,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - DnaB_C,Toprim_4 k59_532600_1 1556290.A0A0A0RL61_9CAUD 1.11e-39 146.0 4QAK6@10239|Viruses,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - GO:0005575,GO:0019012,GO:0019028,GO:0032991,GO:0044423,GO:0046806 - - - - - - - - - - - k59_491827_2 1692253.A0A0K1RLM4_9CIRC 6.41e-32 127.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_239099_3 1437882.AZRU01000111_gene4953 6.94e-36 128.0 2CEI6@1|root,2ZED5@2|Bacteria,1RCK0@1224|Proteobacteria,1SJIE@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF669) - - - - - - - - - - - - DUF669 k59_101961_1 983544.Lacal_0490 7.19e-08 65.9 COG1511@1|root,COG1511@2|Bacteria,4NRM9@976|Bacteroidetes,1I3QV@117743|Flavobacteriia 976|Bacteroidetes UW Hep Hag repeat protein - - - - - - - - - - - - - k59_302609_1 1230338.MOMA_06926 6.55e-18 84.0 COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,1RY1X@1236|Gammaproteobacteria 1236|Gammaproteobacteria S associated with various cellular activities - - - - - - - - - - - - AAA,AAA_5 k59_589381_1 1385658.U5KPZ6_9VIRU 3.25e-60 199.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_262574_2 1223523.H340_01439 1.06e-12 70.5 2DRCF@1|root,33B7F@2|Bacteria,2GM2S@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_35438_1 1172188.KB911824_gene3251 6.46e-28 113.0 COG3409@1|root,COG3409@2|Bacteria,2H001@201174|Actinobacteria,4FIBG@85021|Intrasporangiaceae 201174|Actinobacteria M Peptidoglycan-binding domain 1 protein - - - - - - - - - - - - PG_binding_1 k59_102602_1 1589297.A0A0B5H2N7_9CAUD 2.55e-39 157.0 4QAXA@10239|Viruses,4QQ1A@28883|Caudovirales,4QNU7@10744|Podoviridae 10744|Podoviridae S metallopeptidase activity - - - - - - - - - - - - - k59_20583_2 1536592.A0A088FB29_9VIRU 5.02e-70 221.0 4QB5I@10239|Viruses 10239|Viruses S N-methyltransferase activity - - - - - - - - - - - - - k59_246167_2 267608.RSc3236 7.46e-11 62.0 COG2197@1|root,COG2197@2|Bacteria,1NA3X@1224|Proteobacteria,2VWX0@28216|Betaproteobacteria,1KAW7@119060|Burkholderiaceae 28216|Betaproteobacteria KT phage-related functions and prophages - - - - - - - - - - - - HNH_3 k59_266934_2 1160718.SU9_10414 1.61e-08 62.0 COG2887@1|root,COG2887@2|Bacteria,2IBTP@201174|Actinobacteria 201174|Actinobacteria L Belongs to the helicase family. UvrD subfamily - - - - - - - - - - - - PDDEXK_1 k59_61754_4 1234888.K0A2J2_9VIRU 5.09e-97 307.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_20865_1 1385658.U5KPZ6_9VIRU 1.99e-149 444.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_246496_1 865937.Gilli_0383 1.61e-14 79.0 COG4974@1|root,COG4974@2|Bacteria,4NGE1@976|Bacteroidetes,1HY1D@117743|Flavobacteriia,2P5FE@244698|Gillisia 976|Bacteroidetes L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_int_SAM_4,Phage_integrase k59_451503_1 118168.MC7420_4218 9.8e-14 77.4 28HEE@1|root,2Z7QU@2|Bacteria,1GB7S@1117|Cyanobacteria 1117|Cyanobacteria S Domain of unknown function (DUF932) - - - - - - - - - - - - DUF932 k59_410557_1 1498011.A0A096XUU5_9CAUD 1.04e-34 133.0 4QAUT@10239|Viruses,4QQ7X@28883|Caudovirales,4QNET@10744|Podoviridae 10744|Podoviridae S DNA ligase (ATP) activity - - - - - - - - - - - - - k59_615576_1 366394.Smed_1337 1.27e-140 415.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2TSDW@28211|Alphaproteobacteria,4BCQ8@82115|Rhizobiaceae 28211|Alphaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_348949_1 1385658.U5KPZ6_9VIRU 2.02e-68 226.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_434583_1 186617.M9M8L2_9VIRU 6.5e-50 176.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_476148_2 693746.OBV_02390 1.96e-22 95.9 28MKK@1|root,2ZAWR@2|Bacteria,1UYAT@1239|Firmicutes,24GI2@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - RNA_helicase,Viral_Rep k59_86088_1 1609634.A0A0C5AFV4_9VIRU 1.27e-30 119.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_64827_1 613026.HRAG_02102 2.08e-08 57.8 28K7U@1|root,2Z9VT@2|Bacteria,1RFB2@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - Methyltransf_21 k59_105228_2 1444309.JAQG01000021_gene1432 6.32e-05 46.2 COG0330@1|root,COG0330@2|Bacteria,1UZJK@1239|Firmicutes,4HGVU@91061|Bacilli,26RE7@186822|Paenibacillaceae 91061|Bacilli O HflC protein - - - - - - - - - - - - Band_7 k59_455162_1 1618258.A0A0C5I9K3_9CIRC 2.52e-25 106.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_619021_2 642492.Clole_0798 9.45e-22 97.1 COG3935@1|root,COG3935@2|Bacteria,1V6IW@1239|Firmicutes,24FSU@186801|Clostridia 186801|Clostridia L Domain of unknown function (DUF4373) - - - - - - - - - - - - DUF4373,DnaB_2 k59_372417_1 1220551.SCHR_00760 9.99e-05 50.4 COG3935@1|root,COG3935@2|Bacteria,1TSHD@1239|Firmicutes,4HIGY@91061|Bacilli,4GYXQ@90964|Staphylococcaceae 91061|Bacilli L Conserved phage C-terminus (Phg_2220_C) - - - - - - - - - - - - Phage_rep_org_N,Phg_2220_C k59_188147_3 394503.Ccel_2848 6.45e-16 77.8 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,36DK9@31979|Clostridiaceae 186801|Clostridia L snf2 family - - - - - - - - - - - - SNF2_N k59_476169_1 1676184.A0A186YBN5_9CIRC 6.4e-20 90.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_476169_2 1126411.I1TEL3_9CIRC 2.06e-17 84.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_538016_1 469660.A8HNX4_9CAUD 7.74e-210 589.0 4QBFN@10239|Viruses,4QXWN@35237|dsDNA viruses no RNA stage,4QPTW@28883|Caudovirales,4QNPZ@10744|Podoviridae 10744|Podoviridae S Phage stabilisation protein - - - - - - - - - - - - - k59_188411_2 1176423.I6RTT8_9VIRU 3.62e-16 84.3 4QCMA@10239|Viruses,4QZ56@35237|dsDNA viruses no RNA stage 10239|Viruses - - - - - - - - - - - - - - - k59_598398_1 1173709.M3VMK9_9CIRC 1.27e-49 165.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_65261_1 880070.Cycma_0276 4.02e-27 108.0 COG1896@1|root,COG1896@2|Bacteria,4NUQR@976|Bacteroidetes,47W5J@768503|Cytophagia 976|Bacteroidetes S Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates - - - ko:K06952 - - - - ko00000 - - - - k59_619398_1 1229204.AMYY01000017_gene1284 3.27e-16 83.2 COG1345@1|root,COG1345@2|Bacteria,1QZZ9@1224|Proteobacteria,2TZSX@28211|Alphaproteobacteria 28211|Alphaproteobacteria N Prophage tail length tape measure protein - - - - - - - - - - - - TMP_2 k59_538034_2 1609634.A0A0C5AFV4_9VIRU 2.52e-76 257.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_640683_1 1265502.KB905983_gene550 2.16e-11 72.0 COG5283@1|root,COG5283@2|Bacteria,1R5FU@1224|Proteobacteria,2WFBB@28216|Betaproteobacteria,4AFK0@80864|Comamonadaceae 1224|Proteobacteria NU nuclear chromosome segregation - - - - - - - - - - - - PhageMin_Tail,Tape_meas_lam_C k59_393408_1 1618247.A0A0C5IMK7_9CIRC 3.9e-09 63.2 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_393408_2 110365.A0A023B1R5 8.85e-07 58.2 2EWQP@1|root,2SYH6@2759|Eukaryota 2759|Eukaryota S RNA helicase - - - - - - - - - - - - RNA_helicase,Viral_Rep k59_578025_1 1385658.U5KPZ6_9VIRU 2.65e-10 66.6 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_351914_1 1096546.WYO_0203 3.41e-36 139.0 COG1783@1|root,COG1783@2|Bacteria,1RAGC@1224|Proteobacteria,2U6JF@28211|Alphaproteobacteria 28211|Alphaproteobacteria S phage Terminase large subunit - - - - - - - - - - - - - k59_294610_2 1279009.ADICEAN_01222 6.81e-21 93.6 28WDW@1|root,2ZIE6@2|Bacteria,4NN53@976|Bacteroidetes,47PHU@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_232157_1 1234888.K0A2J2_9VIRU 3.67e-68 223.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_601916_2 1692256.A0A0K1RL85_9CIRC 5.79e-34 132.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_439692_1 1147094.H6X3R8_9CAUD 0.000193 50.1 4QAKZ@10239|Viruses,4QYAE@35237|dsDNA viruses no RNA stage,4QPYH@28883|Caudovirales,4QIM4@10662|Myoviridae 10662|Myoviridae S N-acetyltransferase activity - - - - - - - - - - - - - k59_376594_2 1149133.ppKF707_0787 2.26e-08 63.2 29W4P@1|root,30HPJ@2|Bacteria,1Q0GE@1224|Proteobacteria,1TBBP@1236|Gammaproteobacteria,1YH79@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_522674_1 1038860.AXAP01000067_gene8427 5.05e-62 213.0 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,2U6BJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S TIGRFAM phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_499879_2 411474.COPEUT_01689 7.57e-44 159.0 COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,2484Y@186801|Clostridia 186801|Clostridia J Belongs to the class-I aminoacyl-tRNA synthetase family leuS - 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 k59_397101_2 1385658.U5KPZ6_9VIRU 1.02e-201 579.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_96754_2 926562.Oweho_2720 1.17e-28 117.0 COG0358@1|root,COG0358@2|Bacteria,4NENT@976|Bacteroidetes,1HWVC@117743|Flavobacteriia,2PAHZ@246874|Cryomorphaceae 976|Bacteroidetes L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 k59_72862_3 115991.Q56BB8_9CAUD 8.69e-07 53.1 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QI82@10662|Myoviridae 10662|Myoviridae S virus tail, fiber - - - - - - - - - - - - - k59_342873_2 504832.OCAR_6140 9.29e-06 57.4 28JTG@1|root,2Z9IR@2|Bacteria,1R0GC@1224|Proteobacteria,2TURR@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF2793) - - - - - - - - - - - - DUF2793 k59_400879_3 1122619.KB892340_gene835 1.24e-08 56.6 2EJIR@1|root,33D9N@2|Bacteria,1NHKK@1224|Proteobacteria,2VXU0@28216|Betaproteobacteria 28216|Betaproteobacteria S Phage tail assembly chaperone protein - - - - - - - - - - - - Phage_tail_APC k59_214166_1 1204521.I7B2R2_9CAUD 2.05e-60 209.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QI9F@10662|Myoviridae 10662|Myoviridae S Type III restriction enzyme, res subunit - - - - - - - - - - - - - k59_380932_1 1197951.I6S6K3_9CAUD 4.45e-07 58.2 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales 28883|Caudovirales S N-acetylmuramoyl-L-alanine amidase activity - - - - - - - - - - - - - k59_487522_3 290400.Jann_2321 7.74e-21 90.9 COG3108@1|root,COG3772@1|root,COG3108@2|Bacteria,COG3772@2|Bacteria,1QYHH@1224|Proteobacteria,2UGWI@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Phage lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_154666_1 1486472.A0A068F1U8_9CAUD 3.95e-94 287.0 4QATB@10239|Viruses,4QVUZ@35237|dsDNA viruses no RNA stage,4QPGA@28883|Caudovirales 28883|Caudovirales S Phosphoadenosine phosphosulfate reductase family - - - - - - - - - - - - - k59_258440_1 1610832.A0A0E3M1E6_9CAUD 1.38e-12 68.9 4QAIU@10239|Viruses,4QPDE@28883|Caudovirales 28883|Caudovirales S HNH endonuclease - - - - - - - - - - - - - k59_400894_1 1041159.AZUW01000007_gene5298 1.07e-25 109.0 COG3378@1|root,COG3378@2|Bacteria,1R0JX@1224|Proteobacteria,2TYRR@28211|Alphaproteobacteria,4BHI9@82115|Rhizobiaceae 28211|Alphaproteobacteria S Phage plasmid primase P4 family - - - - - - - - - - - - - k59_548325_3 1027273.GZ77_21170 1.57e-18 90.9 COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,1MVH7@1224|Proteobacteria,1S09Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria KL Belongs to the N(4) N(6)-methyltransferase family - - - - - - - - - - - - N6_N4_Mtase,ParBc k59_487544_1 742733.HMPREF9469_05034 0.000197 47.0 2EAAT@1|root,334F2@2|Bacteria,1VJJI@1239|Firmicutes,24TQU@186801|Clostridia,223KD@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_361689_1 563192.HMPREF0179_01752 2.02e-23 95.9 2C6KN@1|root,32Y69@2|Bacteria,1N8AV@1224|Proteobacteria,433PH@68525|delta/epsilon subdivisions,2WX67@28221|Deltaproteobacteria,2ME4E@213115|Desulfovibrionales 28221|Deltaproteobacteria S VRR_NUC - - - - - - - - - - - - VRR_NUC k59_281589_1 1122962.AULH01000001_gene1565 2.42e-05 48.1 COG3447@1|root,COG5001@1|root,COG3447@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,36XKH@31993|Methylocystaceae 28211|Alphaproteobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GAF,GGDEF,PAS,PAS_3,PAS_9 k59_385479_1 1229751.R9QM99_9CAUD 4.28e-15 77.4 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales,4QKM7@10699|Siphoviridae 10699|Siphoviridae S HNH endonuclease - - - - - - - - - - - - - k59_102470_5 1122146.AUHP01000010_gene1050 2.11e-22 93.6 COG0192@1|root,COG0192@2|Bacteria,1TT9U@1239|Firmicutes,4HUZ6@91061|Bacilli 91061|Bacilli H S-adenosylmethionine synthetase, N-terminal domain - - 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - - S-AdoMet_synt_N k59_200355_1 525904.Tter_1678 3.6e-40 149.0 COG0671@1|root,COG0671@2|Bacteria 2|Bacteria I phosphatidate phosphatase activity - - - - - - - - - - - - PAP2_3 k59_102485_1 1234888.K0A2J2_9VIRU 1.05e-52 182.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_200386_1 742733.HMPREF9469_05032 6.55e-98 298.0 28J3N@1|root,2Z8ZU@2|Bacteria,1V15Z@1239|Firmicutes,249Z0@186801|Clostridia,221RR@1506553|Lachnoclostridium 186801|Clostridia S Phage portal protein - - - - - - - - - - - - Phage_portal k59_631831_2 1476391.X5L4P7_9CAUD 1.16e-30 122.0 4QCT5@10239|Viruses,4QYJH@35237|dsDNA viruses no RNA stage,4QTPG@28883|Caudovirales,4QNK2@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_590277_1 645099.MREP_BBTVA 3.28e-15 76.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_323024_1 10742.Q9MCV7_BPHK0 3.48e-128 390.0 4QBV3@10239|Viruses,4QW0W@35237|dsDNA viruses no RNA stage,4QPPJ@28883|Caudovirales,4QKW5@10699|Siphoviridae 10699|Siphoviridae S Phage Terminase - - - - - - - - - - - - - k59_200949_2 1139219.I569_00086 5.22e-08 58.5 COG3740@1|root,COG3740@2|Bacteria,1VH0Q@1239|Firmicutes,4HZC1@91061|Bacilli 91061|Bacilli S Caudovirus prohead serine protease - - - - - - - - - - - - Peptidase_S78 k59_200958_1 428125.CLOLEP_01422 3.93e-64 221.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia,3WN92@541000|Ruminococcaceae 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_115372_2 1453505.JASY01000039_gene3879 8.98e-12 65.5 2DMPB@1|root,32SV8@2|Bacteria,4NSG4@976|Bacteroidetes,1I3FJ@117743|Flavobacteriia,2NW8N@237|Flavobacterium 976|Bacteroidetes - - - - - - - - - - - - - - - k59_115372_6 753084.F4YCI4_9CAUD 1.21e-133 392.0 4QAIK@10239|Viruses,4QUPH@35237|dsDNA viruses no RNA stage,4QS4V@28883|Caudovirales,4QKNC@10699|Siphoviridae 10699|Siphoviridae S hydrolase activity - - - - - - - - - - - - - k59_348819_3 2003327.CAPSD_BPCHP 1.17e-12 75.5 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_143753_1 349161.Dred_1193 3.16e-70 225.0 COG0863@1|root,COG0863@2|Bacteria,1UZIN@1239|Firmicutes,24CGS@186801|Clostridia 186801|Clostridia L Belongs to the N(4) N(6)-methyltransferase family - - - - - - - - - - - - N6_N4_Mtase k59_143753_2 1123269.NX02_04355 2.18e-42 155.0 COG0553@1|root,COG0553@2|Bacteria,1R7CK@1224|Proteobacteria,2U228@28211|Alphaproteobacteria,2KA8N@204457|Sphingomonadales 28211|Alphaproteobacteria KL DEAD-like helicases superfamily - - - - - - - - - - - - Helicase_C,N6_N4_Mtase k59_328356_1 691965.D4P7B9_9CAUD 1.15e-30 112.0 4QFDH@10239|Viruses,4QWV5@35237|dsDNA viruses no RNA stage,4QPB8@28883|Caudovirales,4QKNN@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_472031_1 756499.Desde_1078 3.74e-45 155.0 2CWXD@1|root,32T0J@2|Bacteria,1V83I@1239|Firmicutes,25DQF@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - AP2 k59_492471_1 1449126.JQKL01000046_gene2072 1.6e-54 192.0 COG1783@1|root,COG1783@2|Bacteria,1TT85@1239|Firmicutes,24ETQ@186801|Clostridia 186801|Clostridia S Psort location Cytoplasmic, score - - - - - - - - - - - - Terminase_6 k59_307763_1 1475143.W8SNN0_9CIRC 2.42e-46 165.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_389840_3 1234888.K0A2J2_9VIRU 2.18e-111 345.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_82399_2 691965.D4P7D6_9CAUD 1.21e-61 212.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_164177_11 1123058.KB894283_gene1542 9.95e-05 51.2 COG3064@1|root,COG5295@1|root,COG3064@2|Bacteria,COG5295@2|Bacteria 2|Bacteria UW Hep Hag repeat protein tek - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - HemolysinCabind,Hint_2,Peptidase_S74 k59_533525_5 1234888.K0A2J2_9VIRU 3.24e-149 441.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_287327_1 1420600.W5RNT1_9CIRC 3.48e-19 87.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_577246_2 1234888.K0A2J2_9VIRU 6.64e-81 267.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_167050_2 160799.PBOR_32325 1.31e-09 70.9 COG5301@1|root,COG5301@2|Bacteria 2|Bacteria G cellulose 1,4-beta-cellobiosidase activity - - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - DUF2793,Phage_fiber_2 k59_167050_9 621372.ACIH01000097_gene2792 2.39e-13 80.9 COG5362@1|root,COG5362@2|Bacteria,1TSQB@1239|Firmicutes,4HUUX@91061|Bacilli,2755X@186822|Paenibacillaceae 91061|Bacilli S TIGRFAM Phage - - - - - - - - - - - - - k59_495330_1 1327977.S0A018_9CAUD 3.66e-07 53.5 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QNBD@10744|Podoviridae 10744|Podoviridae S outer membrane - - - - - - - - - - - - - k59_207298_3 1234888.K0A2J2_9VIRU 9.76e-147 435.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_556905_1 365528.KB891217_gene1474 4.55e-60 200.0 2EW19@1|root,33PEJ@2|Bacteria,2ICKP@201174|Actinobacteria 201174|Actinobacteria S Phage capsid family - - - - - - - - - - - - Phage_capsid k59_434308_1 1540097.A0A0A0YWA1_9CAUD 4.16e-67 220.0 4QCT5@10239|Viruses,4QTPG@28883|Caudovirales,4QNK2@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_434308_2 1406780.U5PZS8_9CAUD 5.3e-117 357.0 4QGGR@10239|Viruses,4QZHR@35237|dsDNA viruses no RNA stage,4QUGZ@28883|Caudovirales,4QNY3@10744|Podoviridae 10744|Podoviridae S viral capsid - - - - - - - - - - - - - k59_537336_10 1123508.JH636454_gene5772 4.36e-21 89.4 2E6IZ@1|root,33162@2|Bacteria 2|Bacteria S Domain of unknown function (DUF4326) - - - - - - - - - - - - DUF4326 k59_85905_2 1230341.MJ3_13664 2.97e-06 54.3 COG0739@1|root,COG5280@1|root,COG5412@1|root,COG0739@2|Bacteria,COG5280@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,4HAFE@91061|Bacilli 91061|Bacilli M Phage tail tape measure protein - - - - - - - - - - - - Peptidase_M23,PhageMin_Tail,SLT k59_351503_2 550540.Fbal_2090 8.37e-65 200.0 2AJWZ@1|root,31AJY@2|Bacteria,1RKGH@1224|Proteobacteria,1S6YJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_332103_1 548479.HMPREF0573_11393 4.76e-32 130.0 COG3740@1|root,COG3740@2|Bacteria,2HBPZ@201174|Actinobacteria,4D6C0@85005|Actinomycetales 201174|Actinobacteria S Caudovirus prohead serine protease - - - ko:K06904 - - - - ko00000 - - - Peptidase_S78 k59_495665_1 998088.B565_3871 1.66e-10 63.5 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1Y479@135624|Aeromonadales 135624|Aeromonadales L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_479935_1 428125.CLOLEP_01417 1.51e-36 130.0 2CGG9@1|root,2ZVSJ@2|Bacteria,1V633@1239|Firmicutes,24HD0@186801|Clostridia,3WMXK@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_479935_2 742733.HMPREF9469_05026 3.23e-84 256.0 28NM4@1|root,2ZBMQ@2|Bacteria,1V1QD@1239|Firmicutes,24G1B@186801|Clostridia,221N8@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_479935_3 691965.D4P7D8_9CAUD 1.56e-41 139.0 4QBBW@10239|Viruses,4QXCP@35237|dsDNA viruses no RNA stage,4QQ3N@28883|Caudovirales,4QN1X@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_479935_4 411460.RUMTOR_01344 1.5e-39 134.0 2E2Y0@1|root,32XYV@2|Bacteria,1VD9S@1239|Firmicutes,24PK0@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_479935_5 691965.D4P7D6_9CAUD 3.27e-219 635.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_479935_6 742740.HMPREF9474_02271 1.96e-129 382.0 28J3N@1|root,2Z8ZU@2|Bacteria,1V15Z@1239|Firmicutes,249Z0@186801|Clostridia,221RR@1506553|Lachnoclostridium 186801|Clostridia S Phage portal protein - - - - - - - - - - - - Phage_portal k59_190620_1 1094497.BVwin_05900 1.19e-25 102.0 2EPJJ@1|root,31453@2|Bacteria,1PTIV@1224|Proteobacteria,2V5E9@28211|Alphaproteobacteria,48UHV@772|Bartonellaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_129380_1 1385658.U5KPZ6_9VIRU 3.42e-46 166.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_457868_1 706587.Desti_2197 9.98e-64 213.0 COG4422@1|root,COG4422@2|Bacteria,1MXQI@1224|Proteobacteria,42WFA@68525|delta/epsilon subdivisions,2X5AZ@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Pfam:Gp37_Gp68 - - - - - - - - - - - - DUF5131 k59_520393_2 391038.Bphy_1919 6.44e-30 114.0 COG2197@1|root,COG2197@2|Bacteria,1NA3X@1224|Proteobacteria,2VWX0@28216|Betaproteobacteria,1KAW7@119060|Burkholderiaceae 28216|Betaproteobacteria KT phage-related functions and prophages - - - - - - - - - - - - HNH_3 k59_498321_1 196490.AUEZ01000005_gene3656 1.24e-69 268.0 COG1749@1|root,COG1749@2|Bacteria,1QWWE@1224|Proteobacteria,2TX6F@28211|Alphaproteobacteria,3JXIB@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria N Domain of unknown function (DUF4082) - - - - - - - - - - - - DUF4082,He_PIG k59_540796_1 670307.HYPDE_26998 3.27e-17 78.6 2E3WG@1|root,32YTM@2|Bacteria,1N8TX@1224|Proteobacteria,2UFMP@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF3768) - - - - - - - - - - - - DUF3768 k59_438133_1 1288298.rosmuc_00464 1.42e-05 55.5 28JTG@1|root,2Z7PY@2|Bacteria,1QVNY@1224|Proteobacteria,2U7ED@28211|Alphaproteobacteria,46PQC@74030|Roseovarius 28211|Alphaproteobacteria S Protein of unknown function (DUF2793) - - - - - - - - - - - - DUF2793 k59_67657_1 1453500.AT05_01505 1.23e-58 198.0 COG4974@1|root,COG4974@2|Bacteria,4NGE1@976|Bacteroidetes,1HY1D@117743|Flavobacteriia 976|Bacteroidetes L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_int_SAM_4,Phage_integrase k59_416333_1 1204521.I7A8M4_9CAUD 1.61e-52 177.0 4QCW5@10239|Viruses,4QWI1@35237|dsDNA viruses no RNA stage,4QQVP@28883|Caudovirales,4QHUS@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_644394_1 1101189.AQUO01000002_gene108 1.09e-41 157.0 COG1961@1|root,COG1961@2|Bacteria,1MV0C@1224|Proteobacteria,2TTJT@28211|Alphaproteobacteria,2PU7A@265|Paracoccus 28211|Alphaproteobacteria L Resolvase, N terminal domain - - - - - - - - - - - - Recombinase,Resolvase,Zn_ribbon_recom k59_480580_1 1051675.G0YQG4_9CAUD 8.62e-123 382.0 4QGA5@10239|Viruses,4QURD@35237|dsDNA viruses no RNA stage,4QT9N@28883|Caudovirales,4QP47@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_293780_2 1123278.KB893559_gene3047 0.000219 46.6 COG0629@1|root,COG0629@2|Bacteria,4NQBK@976|Bacteroidetes,47QZT@768503|Cytophagia 976|Bacteroidetes L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_297537_1 38033.XP_001221915.1 1.01e-08 59.7 COG0445@1|root,KOG2311@2759|Eukaryota,38BWB@33154|Opisthokonta,3NUU9@4751|Fungi,3QJZZ@4890|Ascomycota,211WM@147550|Sordariomycetes,3U4Y1@5139|Sordariales,3HF88@35718|Chaetomiaceae 4751|Fungi J GidA associated domain 3 MTO1 GO:0000166,GO:0000959,GO:0000963,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0030488,GO:0032259,GO:0032543,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043414,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0070525,GO:0070899,GO:0070900,GO:0071704,GO:0090304,GO:0090646,GO:0097159,GO:0140053,GO:1900864,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K03495,ko:K12479 ko04138,ko04144,map04138,map04144 - R08701 RC00053,RC00209,RC00870 ko00000,ko00001,ko03016,ko03036,ko04131 - - - GIDA,GIDA_assoc k59_297537_2 1129146.H2BDF7_9CAUD 1.82e-25 100.0 4QBBN@10239|Viruses,4QUTX@35237|dsDNA viruses no RNA stage,4QPQU@28883|Caudovirales,4QMQE@10699|Siphoviridae 10699|Siphoviridae S Siphovirus Gp157 - - - - - - - - - - - - - k59_462501_1 478749.BRYFOR_08571 1.34e-16 84.0 2A0KC@1|root,31HXF@2|Bacteria,1V8F6@1239|Firmicutes,24K13@186801|Clostridia 186801|Clostridia S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - - k59_485998_1 1038867.AXAY01000025_gene2082 8.24e-43 160.0 COG0417@1|root,COG0417@2|Bacteria,1R7PE@1224|Proteobacteria,2TRUR@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DNA replication proofreading - - - - - - - - - - - - - k59_584599_1 1204521.I7A8M7_9CAUD 1.02e-74 251.0 4QCZC@10239|Viruses,4QX3V@35237|dsDNA viruses no RNA stage,4QRH3@28883|Caudovirales,4QHVR@10662|Myoviridae 10662|Myoviridae S Bacterial DNA polymerase III alpha subunit - - - - - - - - - - - - - k59_420858_1 1268622.AVS7_00732 7.3e-16 82.0 COG5301@1|root,COG5301@2|Bacteria,1NDIE@1224|Proteobacteria 1224|Proteobacteria G cellulose 1,4-beta-cellobiosidase activity - - - - - - - - - - - - - k59_584633_1 411473.RUMCAL_00898 1.51e-51 179.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,3WH0A@541000|Ruminococcaceae 186801|Clostridia L helicase - - - - - - - - - - - - Helicase_C,SNF2_N k59_526562_1 880073.Calab_1470 4.5e-63 202.0 COG0270@1|root,COG0270@2|Bacteria 2|Bacteria L DNA (cytosine-5-)-methyltransferase activity dcm - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_357490_2 991905.SL003B_3788 4.22e-22 96.3 COG3772@1|root,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,2UDUF@28211|Alphaproteobacteria 28211|Alphaproteobacteria G lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - PG_binding_1,Phage_lysozyme k59_297901_1 1517416.IDAT_06825 3.21e-32 127.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,2QFIM@267893|Idiomarinaceae 1236|Gammaproteobacteria L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_213366_1 634956.Geoth_1013 2.44e-27 114.0 COG1459@1|root,COG1459@2|Bacteria,1TQRZ@1239|Firmicutes,4HBFI@91061|Bacilli,1WF24@129337|Geobacillus 91061|Bacilli NU Type II secretion system (T2SS), protein F pilC - - ko:K02653 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSF k59_546920_1 1522072.IL54_1295 1.22e-21 99.4 COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,2TSRZ@28211|Alphaproteobacteria,2K052@204457|Sphingomonadales 204457|Sphingomonadales L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 k59_506695_1 103733.JNYO01000064_gene6458 3.49e-29 130.0 COG2304@1|root,COG2304@2|Bacteria,2HR55@201174|Actinobacteria,4DXBI@85010|Pseudonocardiales 201174|Actinobacteria S oxidoreductase activity - - - - - - - - - - - - VWA_CoxE k59_302223_1 446468.Ndas_4450 1.01e-28 114.0 COG0270@1|root,COG0270@2|Bacteria,2GNB2@201174|Actinobacteria,4EQ02@85012|Streptosporangiales 201174|Actinobacteria L DNA (cytosine-5-)-methyltransferase activity - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - - k59_449714_1 1173762.S4TP25_9CAUD 3.14e-89 288.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_567872_1 232348.ADXL01000068_gene284 3.32e-13 75.1 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1G1P1@1117|Cyanobacteria,1GYN9@1129|Synechococcus 1117|Cyanobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_655890_2 1618248.A0A0C5IB82_9CIRC 1.46e-96 293.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_404511_2 391603.FBALC1_12572 5.71e-12 70.5 COG3209@1|root,COG5295@1|root,COG3209@2|Bacteria,COG5295@2|Bacteria,4PKW4@976|Bacteroidetes,1I1PS@117743|Flavobacteriia 976|Bacteroidetes MUW Chaperone of endosialidase - - - - - - - - - - - - Peptidase_S74,YadA_head k59_114353_2 1038860.AXAP01000067_gene8427 1.53e-85 275.0 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,2U6BJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S TIGRFAM phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_114363_1 1609634.A0A0C5AFV4_9VIRU 1.47e-61 207.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_467986_1 1217656.F964_00519 7.76e-43 145.0 COG3772@1|root,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,1S99W@1236|Gammaproteobacteria,3NKTC@468|Moraxellaceae 1236|Gammaproteobacteria G Phage lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_507017_2 706587.Desti_2304 2.73e-25 119.0 COG3378@1|root,COG3378@2|Bacteria,1MV7I@1224|Proteobacteria,42QE4@68525|delta/epsilon subdivisions,2WM1X@28221|Deltaproteobacteria 28221|Deltaproteobacteria L Phage plasmid primase, P4 family - - - ko:K06919 - - - - ko00000 - - - D5_N,Pox_D5,Toprim_2,zf-CHC2 k59_101936_2 691965.D4P7L5_9CAUD 1.91e-26 101.0 4QG3V@10239|Viruses,4QW5T@35237|dsDNA viruses no RNA stage,4QSWE@28883|Caudovirales,4QM1Q@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_101936_3 428125.CLOLEP_01399 4.13e-72 223.0 29YRZ@1|root,30KMY@2|Bacteria,1V4Y4@1239|Firmicutes,24HPY@186801|Clostridia,3WNNS@541000|Ruminococcaceae 186801|Clostridia S Protein of unknown function (DUF2800) - - - - - - - - - - - - DUF2800 k59_101936_4 691965.D4P7L7_9CAUD 2.41e-283 815.0 4QB9J@10239|Viruses,4QXFE@35237|dsDNA viruses no RNA stage,4QS1Z@28883|Caudovirales,4QN8F@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_239712_1 1122146.AUHP01000010_gene934 3.54e-13 74.3 28JYX@1|root,2Z9P3@2|Bacteria,1V7F3@1239|Firmicutes,4HJ12@91061|Bacilli,3F7KE@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4343) - - - - - - - - - - - - DUF4343 k59_384966_1 626887.J057_07186 4.1e-52 171.0 COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,1RMG9@1236|Gammaproteobacteria,465AV@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) queC - 6.3.4.20 ko:K06920 ko00790,ko01100,map00790,map01100 - R09978 RC00959 ko00000,ko00001,ko01000,ko03016 - - - QueC k59_384966_2 1538804.A0A088F7Y4_9CAUD 7.05e-54 181.0 4QH75@10239|Viruses,4QQZ4@28883|Caudovirales,4QKSF@10699|Siphoviridae 10699|Siphoviridae S GTP cyclohydrolase I activity - - - - - - - - - - - - - k59_101940_1 1054968.G0X4T8_9CAUD 1e-11 71.2 4QAUF@10239|Viruses,4QWIQ@35237|dsDNA viruses no RNA stage,4QUFS@28883|Caudovirales,4QNVK@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_222423_1 880071.Fleli_1980 1.62e-05 55.5 COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes,47JQU@768503|Cytophagia 976|Bacteroidetes N C-terminal domain of CHU protein family - - - - - - - - - - - - CHU_C,PKD,SBBP k59_81784_1 1609634.A0A0C5AFV4_9VIRU 4.67e-10 59.7 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_307461_1 298386.PBPRA1354 2.99e-06 52.8 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,1RPEK@1236|Gammaproteobacteria,1XZMC@135623|Vibrionales 1236|Gammaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_162666_1 471856.Jden_2324 1.56e-31 125.0 2EDV8@1|root,337QD@2|Bacteria,2GTXK@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_244886_1 1556290.A0A0A0RQI3_9CAUD 2.02e-118 372.0 4QCZC@10239|Viruses,4QRH3@28883|Caudovirales,4QM07@10699|Siphoviridae 10699|Siphoviridae S Bacterial DNA polymerase III alpha subunit - - - - - - - - - - - - - k59_119775_1 742741.HMPREF9475_03952 2.82e-40 140.0 2C5J1@1|root,3067M@2|Bacteria,1V52W@1239|Firmicutes,24J2G@186801|Clostridia,221C6@1506553|Lachnoclostridium 186801|Clostridia S COG NOG12663 non supervised orthologous group - - - - - - - - - - - - - k59_81836_1 1187128.I2GUC6_9CAUD 1.07e-19 88.2 4QBHW@10239|Viruses,4QW8N@35237|dsDNA viruses no RNA stage,4QTT7@28883|Caudovirales,4QJZQ@10662|Myoviridae 10662|Myoviridae S sequence-specific DNA binding transcription factor activity - - - - - - - - - - - - - k59_512170_1 1618257.A0A0C5IBI9_9CIRC 8.81e-15 74.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_512170_3 1618260.A0A0C5I2C5_9CIRC 3.11e-23 100.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_512204_2 1379717.S5SY19_9CIRC 3.03e-05 48.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_286438_1 1385658.U5KPZ6_9VIRU 4.3e-99 305.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_222579_1 1125863.JAFN01000001_gene3561 2.71e-07 54.3 COG0791@1|root,COG0791@2|Bacteria,1N732@1224|Proteobacteria,42Y2T@68525|delta/epsilon subdivisions,2WSQU@28221|Deltaproteobacteria 28221|Deltaproteobacteria M NlpC/P60 family - - - - - - - - - - - - NLPC_P60 ## 4257 queries scanned ## Total time (seconds): 75.56374168395996 ## Rate: 56.34 q/s