## Sat Jan 4 12:12:49 2025 ## emapper-2.1.12 ## /data/home/zhuyingjie/miniforge3/envs/eggnog/bin/emapper.py -i /data/home/zhuyingjie/01_Project/01_metagenome/mangrove/mmseqs_cluster/PRJNA437562/SRR6820482/SRR6820482_p_cluster_rep_seq.fasta --output PRJNA437562_SRR6820482 --data_dir /data/software/eggnog_database -m diamond --sensmode fast --output_dir /data/home/zhuyingjie/01_Project/01_metagenome/mangrove/annotation --temp_dir /data/software/eggnog_database/temp --excel --dbmem --cpu 24 ## #query seed_ortholog evalue score eggNOG_OGs max_annot_lvl COG_category Description Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction PFAMs k59_33173_6 290633.GOX2545 1.21e-23 99.8 COG0175@1|root,COG0175@2|Bacteria,1R55Q@1224|Proteobacteria,2UC3A@28211|Alphaproteobacteria,2JURS@204441|Rhodospirillales 204441|Rhodospirillales EH Phosphoadenosine phosphosulfate reductase family - - - - - - - - - - - - PAPS_reduct k59_124398_1 656519.Halsa_1751 4.74e-16 88.6 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia,3WAIG@53433|Halanaerobiales 186801|Clostridia L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_199033_5 1136534.J9PUM4_9CAUD 1.08e-96 310.0 4QY3P@35237|dsDNA viruses no RNA stage,4QQ7H@28883|Caudovirales,4QK0H@10662|Myoviridae 10662|Myoviridae S Terminase-like family - - - - - - - - - - - - - k59_199033_6 1172188.KB911820_gene2845 1.18e-29 111.0 2F5XY@1|root,33YGK@2|Bacteria,2H6A2@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_240509_2 1455626.W5ZKV0_9CIRC 1.35e-37 142.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_74652_1 402612.FP0829 1.11e-74 251.0 COG0358@1|root,COG0358@2|Bacteria,4NIF3@976|Bacteroidetes,1HZ95@117743|Flavobacteriia,2NY6U@237|Flavobacterium 976|Bacteroidetes L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication - - - - - - - - - - - - Toprim_2,Toprim_4,Toprim_N,zf-CHC2 k59_74653_1 1335760.ASTG01000033_gene36 1.02e-88 266.0 COG0863@1|root,COG0863@2|Bacteria 2|Bacteria L N-4 methylation of cytosine - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_132703_1 573174.M4MBI0_9VIRU 7.73e-109 333.0 4QBV3@10239|Viruses,4QW0W@35237|dsDNA viruses no RNA stage 10239|Viruses S Phage Terminase - - - - - - - - - - - - - k59_132703_2 202954.BBNK01000044_gene109 0.000121 47.0 COG4695@1|root,COG4695@2|Bacteria,1MUP5@1224|Proteobacteria,1RPB0@1236|Gammaproteobacteria,3NMGT@468|Moraxellaceae 1236|Gammaproteobacteria S Phage portal protein beeE - - - - - - - - - - - Phage_portal k59_24898_6 398525.KB900701_gene5067 7.78e-19 79.0 2BZTS@1|root,33131@2|Bacteria,1NBBP@1224|Proteobacteria,2UIZA@28211|Alphaproteobacteria,3K1K3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_257099_1 1197951.I6RT34_9CAUD 7.73e-114 342.0 4QGAG@10239|Viruses,4R0KB@35237|dsDNA viruses no RNA stage,4QUA4@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_182455_1 1692242.A0A0K1RKZ2_9CIRC 4.14e-48 169.0 4QFEW@10239|Viruses,4QUKZ@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_182455_2 1692257.A0A0K1RL39_9CIRC 1.4e-74 238.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_232226_1 743721.Psesu_1164 1.33e-29 123.0 COG3170@1|root,COG3170@2|Bacteria,1N4R0@1224|Proteobacteria,1RY0B@1236|Gammaproteobacteria,1X91G@135614|Xanthomonadales 135614|Xanthomonadales NU Tfp pilus assembly protein FimV - - - - - - - - - - - - - k59_91238_1 490913.C4NTE3_9CAUD 8.94e-154 473.0 4QFFI@10239|Viruses,4R00C@35237|dsDNA viruses no RNA stage,4QRHK@28883|Caudovirales,4QNX0@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_16601_2 1385658.U5KPZ6_9VIRU 5.96e-09 57.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_240517_1 1788439.A0A190WHD0_9CIRC 2.42e-40 145.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_141001_1 110365.A0A023AWE7 5.79e-06 55.1 2EWQP@1|root,2SYH6@2759|Eukaryota 2759|Eukaryota S RNA helicase - - - - - - - - - - - - RNA_helicase,Viral_Rep k59_741_2 641107.CDLVIII_1315 1.18e-16 77.0 2C6KN@1|root,32Y69@2|Bacteria,1VANX@1239|Firmicutes,24MNG@186801|Clostridia,36KM4@31979|Clostridiaceae 186801|Clostridia S VRR-NUC domain - - - - - - - - - - - - VRR_NUC k59_50411_2 69328.PVLB_09020 1.62e-45 152.0 COG3793@1|root,COG3793@2|Bacteria,1MZYH@1224|Proteobacteria,1SUJQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria P PFAM Mo-dependent nitrogenase - - - ko:K05793 - - - - ko00000 - - - TerB k59_33939_1 1986029.Q9MBM8_9VIRU 6.38e-27 114.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_92008_1 105154.Q9MBU0_9VIRU 1.52e-07 58.9 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_216451_1 1329516.JPST01000018_gene2643 2.6e-16 85.5 COG2369@1|root,COG2369@2|Bacteria 2|Bacteria K cell adhesion - - - - - - - - - - - - Phage_Mu_F,Phage_min_cap2 k59_125256_5 1609634.A0A0C5AFT2_9VIRU 2.16e-126 371.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_67140_1 1234888.K0A2R8_9VIRU 1.72e-43 156.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_42223_2 1618238.A0A0C5I2G8_9CIRC 5.45e-54 182.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_92012_1 1327990.S0A059_9CAUD 1.95e-41 149.0 4QAIK@10239|Viruses,4QUPH@35237|dsDNA viruses no RNA stage,4QPEB@28883|Caudovirales,4QNC3@10744|Podoviridae 10744|Podoviridae S endonuclease activity - - - - - - - - - - - - - k59_257902_1 105154.Q9MBU0_9VIRU 3.77e-32 122.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_83624_1 1385658.U5KPZ6_9VIRU 7.57e-51 182.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_158212_1 279280.Q6J1R5_9CAUD 1.96e-30 125.0 4QC24@10239|Viruses,4QZPR@35237|dsDNA viruses no RNA stage,4QRZK@28883|Caudovirales,4QP0N@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_207930_1 1156919.QWC_12538 1.57e-64 228.0 COG3170@1|root,COG3170@2|Bacteria,1N4R0@1224|Proteobacteria,2VPR6@28216|Betaproteobacteria 28216|Betaproteobacteria NU Tfp pilus assembly protein FimV - - - - - - - - - - - - P22_portal k59_258727_3 1300005.R9RHA1_9CAUD 1.01e-26 111.0 4QBG0@10239|Viruses,4QWYZ@35237|dsDNA viruses no RNA stage,4QSGM@28883|Caudovirales,4QP2Q@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_26523_1 1475143.W8SNN0_9CIRC 2.99e-13 75.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_142599_1 1479239.JQMU01000001_gene2738 8.93e-30 121.0 COG4653@1|root,COG4653@2|Bacteria,1MWMB@1224|Proteobacteria,2TUJN@28211|Alphaproteobacteria,2K6TT@204457|Sphingomonadales 204457|Sphingomonadales S Phage capsid family - - - - - - - - - - - - Phage_capsid k59_76133_1 1279019.ARQK01000045_gene517 3.21e-25 108.0 COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,1R97W@1224|Proteobacteria,1TK9M@1236|Gammaproteobacteria,1X0PG@135613|Chromatiales 135613|Chromatiales D Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_76133_2 42565.FP66_04595 1.1e-07 53.9 2ER6M@1|root,33IS8@2|Bacteria,1NIM1@1224|Proteobacteria,1SU18@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_175288_1 411460.RUMTOR_01356 4.39e-70 237.0 28JED@1|root,2Z98K@2|Bacteria,1TW1U@1239|Firmicutes,24CFD@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - GerE k59_208504_3 1220601.L7TML5_9CAUD 1.61e-52 175.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales 28883|Caudovirales S N-acetylmuramoyl-L-alanine amidase activity - GO:0005575,GO:0018995,GO:0019012,GO:0030430,GO:0033643,GO:0033646,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044423,GO:0046729 - - - - - - - - - - - k59_208504_5 1197951.I6S2A3_9CAUD 2.26e-15 75.5 4QAIV@10239|Viruses,4QYFZ@35237|dsDNA viruses no RNA stage,4QQUY@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_76135_3 1234888.K0A2J2_9VIRU 1.29e-35 135.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_158709_1 2003327.CAPSD_BPCHP 7.57e-53 187.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_217334_2 1692242.A0A0K1RKZ2_9CIRC 2.28e-23 103.0 4QFEW@10239|Viruses,4QUKZ@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_175735_1 1520935.A0A0H3UB63_9CIRC 1.07e-37 141.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_259162_1 654929.REP_PCV1C 3.75e-27 115.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_143091_2 1094496.m07a_07920 1.04e-17 85.5 COG1044@1|root,COG1044@2|Bacteria,1NBEI@1224|Proteobacteria,2TZFU@28211|Alphaproteobacteria,48URD@772|Bartonellaceae 28211|Alphaproteobacteria M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell - - - - - - - - - - - - - k59_118292_1 2003327.CAPSD_BPCHP 2.77e-37 144.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_167856_1 1379717.S5SY19_9CIRC 2.03e-57 189.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_167856_2 1618236.A0A0C5IB23_9CIRC 2.01e-14 74.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_118294_1 105154.Q9MBU3_9VIRU 8.71e-11 61.6 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_118294_2 105154.Q9MBU6_9VIRU 2.09e-92 288.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_2164_2 1401297.U3PCJ3_9CAUD 1.38e-09 64.3 4QDVQ@10239|Viruses,4QWP4@35237|dsDNA viruses no RNA stage,4QRH2@28883|Caudovirales,4QNEX@10744|Podoviridae 10744|Podoviridae S exonuclease activity - - - - - - - - - - - - - k59_34999_6 411473.RUMCAL_01456 3.54e-07 61.2 COG3378@1|root,COG3378@2|Bacteria,1TQP9@1239|Firmicutes,24AY6@186801|Clostridia 186801|Clostridia L Phage plasmid primase, P4 family - - - ko:K06919 - - - - ko00000 - - - D5_N k59_34999_7 457398.HMPREF0326_03026 2.14e-62 200.0 2D1GK@1|root,32TAP@2|Bacteria,1QV4T@1224|Proteobacteria,43CXG@68525|delta/epsilon subdivisions,2X85J@28221|Deltaproteobacteria,2MFAA@213115|Desulfovibrionales 28221|Deltaproteobacteria L C-5 cytosine-specific DNA methylase - - - - - - - - - - - - - k59_225922_1 352165.HMPREF7215_2558 5.33e-37 146.0 COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria 2|Bacteria L DNA primase activity - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - AAA_25,DUF3987,DnaB_C,Toprim_2,Toprim_4 k59_264911_3 1245471.PCA10_29240 1.18e-76 249.0 COG4128@1|root,COG4128@2|Bacteria,1RK87@1224|Proteobacteria,1SYAX@1236|Gammaproteobacteria,1YH69@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Zonular occludens toxin (Zot) - - - ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko02042 - - - Zot k59_264911_4 181604.Q8W6D1_9VIRU 5.37e-07 51.6 4QGF7@10239|Viruses,4QUKH@29258|ssDNA viruses,4QP4F@10860|Inoviridae 10860|Inoviridae S Protein of unknown function (DUF2523) - - - - - - - - - - - - - k59_15513_1 926566.Terro_1757 1.75e-10 57.4 2FDB9@1|root,345D5@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_57888_1 1510531.JQJJ01000013_gene47 1.47e-13 73.6 COG0500@1|root,COG2226@2|Bacteria,1N73D@1224|Proteobacteria,2U7VH@28211|Alphaproteobacteria,3K61C@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_11 k59_23922_2 33898.JRHJ01000001_gene713 1.74e-21 90.9 2EHNC@1|root,33BE4@2|Bacteria,2IPVK@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - Phage_tail_2 k59_157514_1 1618247.A0A0C5IMK7_9CIRC 0.000391 48.9 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_98066_1 753084.F4YCI4_9CAUD 9.69e-57 189.0 4QAIK@10239|Viruses,4QUPH@35237|dsDNA viruses no RNA stage,4QS4V@28883|Caudovirales,4QKNC@10699|Siphoviridae 10699|Siphoviridae S hydrolase activity - - - - - - - - - - - - - k59_23929_2 3702.AT1G30680.1 4.42e-33 132.0 28HK1@1|root,2QPXS@2759|Eukaryota,37NXW@33090|Viridiplantae,3GF00@35493|Streptophyta,3HSRU@3699|Brassicales 35493|Streptophyta L nucleotidyltransferase activity - GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003697,GO:0003824,GO:0003896,GO:0003899,GO:0004003,GO:0004386,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016043,GO:0016070,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032392,GO:0032508,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051276,GO:0055086,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090407,GO:0097159,GO:0097747,GO:0140097,GO:0140098,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - AAA_25,DnaB_C,Toprim_4 k59_181978_1 765765.I3UMF6_9CAUD 1.12e-10 70.1 4QBMV@10239|Viruses,4QUU6@35237|dsDNA viruses no RNA stage,4QQ7Y@28883|Caudovirales,4QKR8@10699|Siphoviridae 10699|Siphoviridae S DNA-directed RNA polymerase activity - - - - - - - - - - - - - k59_214346_2 1692242.A0A0K1RL37_9CIRC 2.39e-07 55.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_247509_3 1120705.FG95_03264 1.16e-08 54.7 COG1396@1|root,COG1396@2|Bacteria,1ND0I@1224|Proteobacteria,2UIAT@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Transcriptional Regulator, XRE family - - - - - - - - - - - - HTH_3 k59_198199_1 1235689.K4NZ61_9CAUD 1.12e-09 60.1 4QAQA@10239|Viruses,4QXB8@35237|dsDNA viruses no RNA stage,4QQ03@28883|Caudovirales,4QNPC@10744|Podoviridae 10744|Podoviridae S NinB protein - - - - - - - - - - - - - k59_264930_4 145579.REP_BPPHM 8.4e-39 145.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_264930_9 105154.Q9MBU6_9VIRU 2.4e-204 586.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_165323_4 1382315.JPOI01000001_gene269 1.42e-12 68.9 COG1388@1|root,COG1876@1|root,COG1388@2|Bacteria,COG1876@2|Bacteria,1V8X4@1239|Firmicutes,4I29S@91061|Bacilli,1WHJU@129337|Geobacillus 91061|Bacilli M D-alanyl-D-alanine carboxypeptidase - - - ko:K17733 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M15_4 k59_207471_2 352165.HMPREF7215_2591 7.85e-17 80.9 COG5410@1|root,COG5410@2|Bacteria 2|Bacteria K chromosome segregation - - - - - - - - - - - - Terminase_6,Terminase_6C k59_107977_1 1385658.U5KPZ6_9VIRU 3.34e-96 301.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_66498_15 1121342.AUCO01000004_gene630 2.16e-33 137.0 COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,1TPHP@1239|Firmicutes,249MR@186801|Clostridia,36FKT@31979|Clostridiaceae 186801|Clostridia KL Belongs to the N(4) N(6)-methyltransferase family - - - - - - - - - - - - N6_N4_Mtase,ParBc k59_66498_24 469617.FUAG_00827 2.88e-69 227.0 COG0863@1|root,COG0863@2|Bacteria,37A63@32066|Fusobacteria 32066|Fusobacteria L DNA methylase - - 2.1.1.113 ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_66498_32 1459636.NTE_01091 8.76e-22 93.6 COG0468@1|root,arCOG00415@2157|Archaea,41SBA@651137|Thaumarchaeota 651137|Thaumarchaeota L Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules radA - - ko:K04483 - - - - ko00000,ko03400 - - - HHH_5,Rad51 k59_99668_3 1165094.RINTHH_3920 1.54e-75 240.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_91414_1 1500301.JQMF01000006_gene1773 6.35e-51 183.0 COG5108@1|root,COG5108@2|Bacteria,1PIWB@1224|Proteobacteria,2U1JR@28211|Alphaproteobacteria,4BC0X@82115|Rhizobiaceae 28211|Alphaproteobacteria K DNA-directed RNA polymerase N-terminal - - - - - - - - - - - - RNA_pol,RPOL_N k59_215816_1 1530454.A0A076JTZ1_9CIRC 4.8e-17 87.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_108054_1 1618247.A0A0C5IMK7_9CIRC 0.000166 50.4 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_49975_1 1197951.I6RT34_9CAUD 4.14e-103 315.0 4QGAG@10239|Viruses,4R0KB@35237|dsDNA viruses no RNA stage,4QUA4@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_182614_6 1618256.A0A0C5IM93_9CIRC 1.18e-05 50.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_207531_1 7739.XP_002605658.1 5.68e-07 57.4 KOG1565@1|root,KOG1565@2759|Eukaryota,38CRR@33154|Opisthokonta,3B9IY@33208|Metazoa,3CT1E@33213|Bilateria,47ZW6@7711|Chordata 33208|Metazoa OW Belongs to the peptidase M10A family MMP15 GO:0000003,GO:0000139,GO:0000902,GO:0000904,GO:0001501,GO:0001503,GO:0001525,GO:0001541,GO:0001558,GO:0001568,GO:0001666,GO:0001704,GO:0001706,GO:0001763,GO:0001838,GO:0001935,GO:0001944,GO:0001952,GO:0001953,GO:0001958,GO:0002009,GO:0002165,GO:0002218,GO:0002253,GO:0002376,GO:0002682,GO:0002684,GO:0002685,GO:0002687,GO:0002694,GO:0002696,GO:0003006,GO:0003007,GO:0003008,GO:0003143,GO:0003144,GO:0003313,GO:0003314,GO:0003315,GO:0003318,GO:0003319,GO:0003674,GO:0003824,GO:0004175,GO:0004177,GO:0004222,GO:0004252,GO:0005102,GO:0005178,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005768,GO:0005794,GO:0005796,GO:0005802,GO:0005829,GO:0005856,GO:0005886,GO:0005887,GO:0006464,GO:0006508,GO:0006807,GO:0006928,GO:0006929,GO:0006935,GO:0006950,GO:0006979,GO:0007154,GO:0007155,GO:0007162,GO:0007267,GO:0007275,GO:0007276,GO:0007292,GO:0007369,GO:0007399,GO:0007409,GO:0007411,GO:0007413,GO:0007417,GO:0007419,GO:0007424,GO:0007426,GO:0007444,GO:0007492,GO:0007503,GO:0007505,GO:0007507,GO:0007548,GO:0007552,GO:0007560,GO:0007561,GO:0007600,GO:0008037,GO:0008038,GO:0008045,GO:0008047,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008236,GO:0008237,GO:0008238,GO:0008270,GO:0008283,GO:0008285,GO:0008347,GO:0008406,GO:0008584,GO:0008585,GO:0008593,GO:0009056,GO:0009266,GO:0009581,GO:0009582,GO:0009605,GO:0009611,GO:0009612,GO:0009628,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009791,GO:0009792,GO:0009886,GO:0009887,GO:0009888,GO:0009893,GO:0009897,GO:0009966,GO:0009968,GO:0009986,GO:0009987,GO:0010001,GO:0010033,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0010646,GO:0010648,GO:0010810,GO:0010812,GO:0010830,GO:0010831,GO:0010952,GO:0010954,GO:0012505,GO:0014070,GO:0016020,GO:0016021,GO:0016043,GO:0016048,GO:0016331,GO:0016477,GO:0016485,GO:0016504,GO:0016787,GO:0017171,GO:0019222,GO:0019233,GO:0019538,GO:0019827,GO:0019953,GO:0022008,GO:0022411,GO:0022414,GO:0022610,GO:0022617,GO:0023051,GO:0023052,GO:0023057,GO:0030030,GO:0030111,GO:0030154,GO:0030155,GO:0030162,GO:0030178,GO:0030182,GO:0030198,GO:0030234,GO:0030307,GO:0030323,GO:0030324,GO:0030334,GO:0030335,GO:0030425,GO:0030574,GO:0030728,GO:0031090,GO:0031175,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031347,GO:0031349,GO:0031410,GO:0031638,GO:0031974,GO:0031982,GO:0031984,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032504,GO:0032588,GO:0032879,GO:0032963,GO:0032989,GO:0032990,GO:0034330,GO:0034769,GO:0035050,GO:0035148,GO:0035202,GO:0035239,GO:0035295,GO:0035987,GO:0035988,GO:0036075,GO:0036211,GO:0036293,GO:0036477,GO:0040008,GO:0040011,GO:0040012,GO:0040017,GO:0040036,GO:0040037,GO:0042060,GO:0042063,GO:0042127,GO:0042221,GO:0042330,GO:0042470,GO:0042995,GO:0043005,GO:0043009,GO:0043062,GO:0043085,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043615,GO:0043627,GO:0044087,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044331,GO:0044352,GO:0044354,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0044703,GO:0044877,GO:0045088,GO:0045089,GO:0045111,GO:0045137,GO:0045165,GO:0045168,GO:0045216,GO:0045296,GO:0045577,GO:0045579,GO:0045595,GO:0045597,GO:0045619,GO:0045621,GO:0045746,GO:0045862,GO:0045927,GO:0046331,GO:0046528,GO:0046529,GO:0046545,GO:0046546,GO:0046660,GO:0046661,GO:0046872,GO:0046914,GO:0048468,GO:0048513,GO:0048514,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048562,GO:0048563,GO:0048568,GO:0048569,GO:0048583,GO:0048584,GO:0048585,GO:0048598,GO:0048608,GO:0048609,GO:0048646,GO:0048666,GO:0048667,GO:0048699,GO:0048701,GO:0048704,GO:0048705,GO:0048706,GO:0048707,GO:0048729,GO:0048731,GO:0048754,GO:0048770,GO:0048771,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048870,GO:0050673,GO:0050776,GO:0050778,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050839,GO:0050864,GO:0050865,GO:0050867,GO:0050871,GO:0050877,GO:0050896,GO:0050906,GO:0050951,GO:0050961,GO:0050965,GO:0051094,GO:0051128,GO:0051129,GO:0051147,GO:0051149,GO:0051153,GO:0051155,GO:0051171,GO:0051173,GO:0051179,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051249,GO:0051251,GO:0051270,GO:0051272,GO:0051336,GO:0051345,GO:0051604,GO:0051606,GO:0051674,GO:0051704,GO:0051893,GO:0051895,GO:0052547,GO:0060255,GO:0060322,GO:0060348,GO:0060349,GO:0060350,GO:0060429,GO:0060541,GO:0060562,GO:0060612,GO:0060828,GO:0060973,GO:0061134,GO:0061138,GO:0061448,GO:0061458,GO:0061564,GO:0065007,GO:0065009,GO:0070006,GO:0070011,GO:0070013,GO:0070482,GO:0070613,GO:0071704,GO:0071711,GO:0071840,GO:0071944,GO:0072091,GO:0072175,GO:0072358,GO:0072359,GO:0080090,GO:0080134,GO:0090090,GO:0090109,GO:0090287,GO:0090288,GO:0097094,GO:0097150,GO:0097156,GO:0097447,GO:0097458,GO:0097485,GO:0097708,GO:0098552,GO:0098588,GO:0098609,GO:0098727,GO:0098742,GO:0098772,GO:0098791,GO:0106030,GO:0120025,GO:0120036,GO:0120038,GO:0120039,GO:0140096,GO:1901201,GO:1901202,GO:1901564,GO:1901888,GO:1901889,GO:1902105,GO:1902107,GO:1903053,GO:1903054,GO:1903317,GO:1903319,GO:1903391,GO:1903392,GO:1903706,GO:1903708,GO:1904888,GO:1905521,GO:1905523,GO:1990834,GO:2000026,GO:2000145,GO:2000147,GO:2000647 3.4.24.80 ko:K07763,ko:K07995,ko:K07996,ko:K07997,ko:K08002,ko:K08003 ko04668,ko04912,ko05206,map04668,map04912,map05206 - - - ko00000,ko00001,ko01000,ko01002 - - - DUF3377,Hemopexin,PG_binding_1,Peptidase_M10 k59_116342_4 105154.Q9MBU6_9VIRU 2.35e-170 501.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_99672_4 512565.AMIS_2500 1.66e-08 55.5 2DBIJ@1|root,2Z9G2@2|Bacteria,2IB2V@201174|Actinobacteria,4DKXD@85008|Micromonosporales 201174|Actinobacteria - - - - - - - - - - - - - - - k59_83144_1 1168281.I3PUX6_9CAUD 3.1e-22 99.4 4QCM6@10239|Viruses,4QVAQ@35237|dsDNA viruses no RNA stage,4QPVV@28883|Caudovirales,4QNID@10744|Podoviridae 10744|Podoviridae S actin binding - - - - - - - - - - - - - k59_49976_2 198467.NP92_00275 4.91e-24 102.0 COG1388@1|root,COG3023@1|root,COG3409@1|root,COG1388@2|Bacteria,COG3023@2|Bacteria,COG3409@2|Bacteria,1V5SV@1239|Firmicutes,4HI8B@91061|Bacilli,21WNR@150247|Anoxybacillus 91061|Bacilli MV Ami_2 - - - - - - - - - - - - Amidase_2,Cu_amine_oxidN1,LysM,PG_binding_1 k59_257333_5 1279017.AQYJ01000008_gene2558 7.09e-44 147.0 2BI7V@1|root,32CD5@2|Bacteria,1NEIV@1224|Proteobacteria,1T0WD@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_257333_7 1429767.W6B150_9CAUD 1.73e-36 140.0 4QF3C@10239|Viruses,4QWIA@35237|dsDNA viruses no RNA stage,4QU4U@28883|Caudovirales,4QNNQ@10744|Podoviridae 10744|Podoviridae S host cell wall - - - - - - - - - - - - - k59_215818_3 378806.STAUR_4357 3.09e-09 66.2 COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,42MNA@68525|delta/epsilon subdivisions,2X3SJ@28221|Deltaproteobacteria,2YX0A@29|Myxococcales 28221|Deltaproteobacteria OU Signal peptide peptidase sppA - - ko:K04773 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49 k59_42255_1 1392540.P256_00045 1e-25 98.6 2BRZC@1|root,32KZQ@2|Bacteria,1Q31I@1224|Proteobacteria,1RSVN@1236|Gammaproteobacteria,3NRT9@468|Moraxellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_141844_3 1385658.U5KPZ6_9VIRU 1.48e-218 622.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_141844_7 1385658.U5KNR1_9VIRU 1.67e-59 197.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_241230_3 691965.D4P7L3_9CAUD 1.41e-112 346.0 4QBH7@10239|Viruses,4QWWF@35237|dsDNA viruses no RNA stage,4QQ8R@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_241230_4 691965.D4P7I8_9CAUD 4.71e-16 79.3 4QGJH@10239|Viruses,4QZ35@35237|dsDNA viruses no RNA stage,4QRZS@28883|Caudovirales,4QMAA@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_241230_5 478749.BRYFOR_08560 1.8e-08 60.8 COG3378@1|root,COG3378@2|Bacteria 2|Bacteria KL Phage plasmid primase P4 family - - - ko:K06919 - - - - ko00000 - - - D5_N,DUF3854,P22_AR_N,Pox_D5 k59_207944_2 1609634.A0A0C5ANA6_9VIRU 2.8e-40 144.0 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_207944_3 1609634.A0A0C5AFV4_9VIRU 3.26e-277 771.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_207944_6 1609634.A0A0C5AFT2_9VIRU 5.1e-154 441.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_241231_3 315750.BPUM_0561 1.32e-18 88.2 COG0270@1|root,COG0270@2|Bacteria,1TPNE@1239|Firmicutes,4IPQ7@91061|Bacilli,1ZGRG@1386|Bacillus 91061|Bacilli H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006304,GO:0006305,GO:0006306,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0008150,GO:0008152,GO:0008168,GO:0009307,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0032776,GO:0034641,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044355,GO:0044728,GO:0046483,GO:0050896,GO:0071704,GO:0090304,GO:0099046,GO:1901360 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_216504_3 930946.AEOP01000051_gene630 1.11e-22 98.6 2B9XI@1|root,323AV@2|Bacteria,1V7VV@1239|Firmicutes,4HK2T@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF1071) - - - - - - - - - - - - DUF1071 k59_50605_2 694427.Palpr_1970 1.18e-31 133.0 COG4675@1|root,COG4675@2|Bacteria 2|Bacteria M tail collar domain protein - - - - - - - - - - - - Collar k59_249600_1 313612.L8106_17677 1.58e-45 165.0 COG3179@1|root,COG3409@1|root,COG3770@1|root,COG3179@2|Bacteria,COG3409@2|Bacteria,COG3770@2|Bacteria,1G1SC@1117|Cyanobacteria,1H7Z0@1150|Oscillatoriales 1117|Cyanobacteria M Chitinase class I - - - - - - - - - - - - Glyco_hydro_19,PG_binding_1,Peptidase_M74,VanY k59_166724_2 1536592.A0A088F742_9VIRU 8.44e-24 93.2 4QAQV@10239|Viruses 10239|Viruses S protein disulfide oxidoreductase activity - - - - - - - - - - - - - k59_25831_1 1217710.F969_00023 9.67e-52 191.0 291GM@1|root,2ZP3A@2|Bacteria,1RD1E@1224|Proteobacteria,1S4X6@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_200341_1 78398.KS43_20360 6.39e-05 54.7 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,1RR0M@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_26630_3 1986029.Q9MBM3_9VIRU 5.13e-32 125.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_142686_3 1234888.K0A2J2_9VIRU 2.72e-47 167.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_17669_1 145579.REP_BPPHM 8.81e-10 66.2 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_17669_3 1234888.K0A2J2_9VIRU 1.72e-154 455.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_208612_1 1123487.KB892865_gene1391 3.98e-121 365.0 COG0553@1|root,COG0553@2|Bacteria,1PN7I@1224|Proteobacteria,2VP2N@28216|Betaproteobacteria 28216|Betaproteobacteria L Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair - - - - - - - - - - - - SNF2_N k59_250176_2 1692253.A0A0K1RLM4_9CIRC 4.82e-18 85.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_43080_1 706587.Desti_1849 4.29e-40 157.0 COG0726@1|root,COG0726@2|Bacteria,1QZSR@1224|Proteobacteria,43D4Q@68525|delta/epsilon subdivisions 1224|Proteobacteria G PFAM Polysaccharide deacetylase - - - - - - - - - - - - Cadherin_3,Polysacc_deac_1 k59_43634_88 530564.Psta_0658 1.34e-49 184.0 COG5362@1|root,COG5362@2|Bacteria,2J0FK@203682|Planctomycetes 203682|Planctomycetes S Terminase-like family - - - - - - - - - - - - Terminase_6 k59_159455_1 1379713.S5SYD9_9CIRC 3.02e-25 104.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_250606_1 1123508.JH636446_gene6153 6.19e-32 137.0 COG4733@1|root,COG4733@2|Bacteria 2|Bacteria S cellulase activity - - - ko:K07451 - - - - ko00000,ko01000,ko02048 - - - Alginate_lyase,Big_2,F5_F8_type_C,Glyco_hydro_25,Phage-tail_3,SLH,fn3 k59_209147_2 1223542.GM1_041_00390 3.92e-24 105.0 COG1074@1|root,COG1074@2|Bacteria,2ICR2@201174|Actinobacteria,4GG6F@85026|Gordoniaceae 201174|Actinobacteria L PDDEXK-like domain of unknown function (DUF3799) - - - - - - - - - - - - DUF3799 k59_52119_1 1279019.ARQK01000045_gene517 6.64e-95 307.0 COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,1R97W@1224|Proteobacteria,1TK9M@1236|Gammaproteobacteria,1X0PG@135613|Chromatiales 135613|Chromatiales D Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_159458_1 1158150.KB906242_gene214 3.82e-22 97.8 COG0258@1|root,COG0258@2|Bacteria,1MYSI@1224|Proteobacteria,1SQ55@1236|Gammaproteobacteria 1236|Gammaproteobacteria L 5'-3' exonuclease, N-terminal resolvase-like domain - - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc_N k59_259514_1 1123072.AUDH01000066_gene1969 7.02e-06 53.1 COG5511@1|root,COG5511@2|Bacteria,1MVN4@1224|Proteobacteria,2TSGI@28211|Alphaproteobacteria,2JSIQ@204441|Rhodospirillales 204441|Rhodospirillales S COG5511 Bacteriophage capsid protein - - - - - - - - - - - - Phage_portal_2 k59_184444_2 1385658.U5KPZ6_9VIRU 6.23e-48 168.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_59983_2 105154.Q9MBU3_9VIRU 1.21e-09 62.8 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_59983_5 1165094.RINTHH_3920 2.6e-41 147.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_176089_1 1121448.DGI_2053 1.81e-102 321.0 COG4653@1|root,COG4653@2|Bacteria,1MXMN@1224|Proteobacteria,42UKA@68525|delta/epsilon subdivisions,2WQZV@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Phage capsid family - - - - - - - - - - - - Phage_capsid k59_143605_1 69279.BG36_20875 4.05e-43 155.0 COG1783@1|root,COG4373@1|root,COG1783@2|Bacteria,COG4373@2|Bacteria,1PE12@1224|Proteobacteria,2V9EC@28211|Alphaproteobacteria,43QJZ@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Mu-like prophage FluMu protein gp28 - - - - - - - - - - - - - k59_110111_1 9258.ENSOANP00000025670 3.55e-06 50.8 2BF6Y@1|root,2S16D@2759|Eukaryota,3A216@33154|Opisthokonta,3BQXI@33208|Metazoa,3D8B1@33213|Bilateria,48BMF@7711|Chordata,49B3K@7742|Vertebrata,3JCMZ@40674|Mammalia 33208|Metazoa S taxis LECT2 GO:0001501,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0006935,GO:0007275,GO:0008150,GO:0009605,GO:0009966,GO:0009968,GO:0010646,GO:0010648,GO:0023051,GO:0023057,GO:0030111,GO:0030178,GO:0032501,GO:0032502,GO:0040011,GO:0042221,GO:0042330,GO:0042802,GO:0044421,GO:0044424,GO:0044464,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0048731,GO:0048856,GO:0050789,GO:0050794,GO:0050896,GO:0065007 - - - - - - - - - - Peptidase_M23 k59_259611_1 259536.Psyc_1128 1.55e-84 279.0 COG1330@1|root,COG1330@2|Bacteria,1MWTI@1224|Proteobacteria,1RNT0@1236|Gammaproteobacteria,3NM1F@468|Moraxellaceae 1236|Gammaproteobacteria L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity recC GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008854,GO:0009314,GO:0009338,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016887,GO:0016895,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044355,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0099046,GO:0140097,GO:1901360,GO:1902494 3.1.11.5 ko:K03583 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_V_gamma k59_43747_2 1121459.AQXE01000001_gene2749 6.11e-35 140.0 28IA2@1|root,2Z8CQ@2|Bacteria,1PQM2@1224|Proteobacteria,42Y9U@68525|delta/epsilon subdivisions,2WTUC@28221|Deltaproteobacteria,2MARZ@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_36286_3 1005994.GTGU_01424 4.07e-05 53.1 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,1RR0M@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_227469_3 1122201.AUAZ01000017_gene2968 9.8e-75 231.0 COG1702@1|root,COG1702@2|Bacteria 2|Bacteria T phosphate starvation-inducible protein PhoH phoH GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K06217 - - - - ko00000 - - - PhoH k59_160725_1 10855.CAPSD_SPV4 1.03e-38 147.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_210173_1 649638.Trad_1811 2.73e-09 61.2 COG4974@1|root,COG4974@2|Bacteria,1WKPJ@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus L Belongs to the 'phage' integrase family - - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_integrase k59_185785_1 145579.CAPSD_BPPHM 1.79e-47 169.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_102811_7 1449347.JQLN01000004_gene6907 2.91e-20 97.4 2BMCR@1|root,32FWY@2|Bacteria,2GZKQ@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_94251_1 1121861.KB899915_gene1863 1.52e-09 65.9 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,2TVGJ@28211|Alphaproteobacteria,2JPR0@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - k59_193647_1 1319815.HMPREF0202_02631 4.09e-35 147.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,378G8@32066|Fusobacteria 32066|Fusobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,HHH_5 k59_60960_3 1788455.A0A190WHF5_9CIRC 3.23e-60 199.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_136270_1 49964.Q94MS4_9CAUD 1.12e-57 210.0 4QCUF@10239|Viruses,4QV7U@35237|dsDNA viruses no RNA stage,4QQ89@28883|Caudovirales,4QNCY@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_28736_1 1385658.U5KNR1_9VIRU 6.21e-70 226.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_227479_1 1423144.Gal_01774 1.21e-11 70.9 COG4653@1|root,COG4653@2|Bacteria,1MWU1@1224|Proteobacteria,2TSSY@28211|Alphaproteobacteria,34E9B@302485|Phaeobacter 28211|Alphaproteobacteria S Phage capsid family - - - - - - - - - - - - Phage_capsid k59_11414_1 266940.Krad_0558 1.19e-11 69.7 COG4124@1|root,COG4124@2|Bacteria,2GN8K@201174|Actinobacteria 201174|Actinobacteria G Belongs to the glycosyl hydrolase 26 family - - - - - - - - - - - - Glyco_hydro_26 k59_102934_1 1415780.JPOG01000001_gene1744 4.42e-23 110.0 COG0454@1|root,COG0827@1|root,COG1040@1|root,COG3087@1|root,COG0456@2|Bacteria,COG0827@2|Bacteria,COG1040@2|Bacteria,COG3087@2|Bacteria,1PI1K@1224|Proteobacteria,1T6BU@1236|Gammaproteobacteria,1XB7I@135614|Xanthomonadales 135614|Xanthomonadales D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - - - - - - - - - - - k59_102934_2 3218.PP1S44_312V6.1 3.16e-62 205.0 2CM75@1|root,2QPHU@2759|Eukaryota,37NYC@33090|Viridiplantae,3G7BP@35493|Streptophyta 35493|Streptophyta - - - GO:0000003,GO:0000902,GO:0000904,GO:0003006,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009653,GO:0009826,GO:0009846,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0016043,GO:0016049,GO:0022414,GO:0030154,GO:0032501,GO:0032502,GO:0032989,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0044706,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048868,GO:0048869,GO:0051704,GO:0060560,GO:0071840 - - - - - - - - - - - k59_70654_3 700598.Niako_1586 1.25e-06 52.0 COG0629@1|root,COG0629@2|Bacteria,4NQBK@976|Bacteroidetes 976|Bacteroidetes L single-stranded DNA-binding protein ssb1 - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_86370_1 358681.BBR47_17750 2.74e-23 102.0 COG1404@1|root,COG5184@1|root,COG5492@1|root,COG1404@2|Bacteria,COG5184@2|Bacteria,COG5492@2|Bacteria,1TQ2M@1239|Firmicutes,4HBYC@91061|Bacilli,27491@186822|Paenibacillaceae 91061|Bacilli O Subtilase family - - - ko:K13277 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - A2M_N,Big_2,Peptidase_S8,fn3 k59_78948_2 1385658.U5KNR1_9VIRU 1.96e-71 231.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_78948_3 105154.Q9MBT9_9VIRU 2.82e-13 66.2 4QCC5@10239|Viruses,4QUKW@29258|ssDNA viruses,4QP4C@10841|Microviridae 10841|Microviridae S viral process - - - - - - - - - - - - - k59_78948_4 1609634.A0A0C5AFV4_9VIRU 1.19e-156 464.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_78948_5 1609634.A0A0C5ANA6_9VIRU 7.84e-06 53.1 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_203556_2 110365.A0A023AX31 0.000533 48.5 2EWQP@1|root,2SYH6@2759|Eukaryota 2759|Eukaryota S RNA helicase - - - - - - - - - - - - RNA_helicase,Viral_Rep k59_129521_2 1123508.JH636439_gene766 2.92e-40 155.0 COG0553@1|root,COG0553@2|Bacteria,2IX46@203682|Planctomycetes 203682|Planctomycetes KL helicase superfamily c-terminal domain - - - - - - - - - - - - Helicase_C,SNF2_N,SWIM k59_86373_2 1165094.RINTHH_3920 3.86e-31 119.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_37272_2 1385658.U5KPZ6_9VIRU 1.17e-217 619.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_37272_3 105154.Q9MBU3_9VIRU 1.53e-07 57.4 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_37272_5 1165094.RINTHH_3920 3.36e-81 256.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_221273_1 1123288.SOV_6c01580 1.2e-26 111.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4H2W4@909932|Negativicutes 909932|Negativicutes L SNF2 family - - - - - - - - - - - - Helicase_C,SNF2_N k59_186991_1 145579.CAPSD_BPPHM 1.64e-53 184.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_186991_3 1385658.U5KNR1_9VIRU 5.76e-65 214.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_103780_1 2003327.CAPSD_BPCHP 2.12e-44 172.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_121006_1 118173.KB235914_gene2002 7.6e-28 118.0 COG2369@1|root,COG2369@2|Bacteria 2|Bacteria K cell adhesion - - - - - - - - - - - - Phage_Mu_F k59_194645_1 1249975.JQLP01000001_gene3212 1.34e-34 137.0 COG0582@1|root,COG0582@2|Bacteria,4NDZJ@976|Bacteroidetes,1HZ88@117743|Flavobacteriia 976|Bacteroidetes L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_5,Phage_int_SAM_5,Phage_integrase k59_104379_1 742733.HMPREF9469_05020 1.89e-44 171.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia,221IX@1506553|Lachnoclostridium 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_253198_1 2003327.CAPSD_BPCHP 0.000133 50.1 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_86997_1 1141136.K4F701_9CAUD 1.81e-22 100.0 4QB06@10239|Viruses,4QVR3@35237|dsDNA viruses no RNA stage,4QRS4@28883|Caudovirales,4QIQJ@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_30541_1 323098.Nwi_0796 8.87e-29 113.0 COG5448@1|root,COG5448@2|Bacteria,1MXM8@1224|Proteobacteria,2U8KA@28211|Alphaproteobacteria,3K44P@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Conserved hypothetical protein 2217 (DUF2460) - - - - - - - - - - - - DUF2460 k59_20866_1 742740.HMPREF9474_02278 4.03e-97 316.0 28JED@1|root,2Z98K@2|Bacteria,1TW1U@1239|Firmicutes,24CFD@186801|Clostridia,2226E@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - GerE k59_204431_2 460265.Mnod_4078 5.39e-45 160.0 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,2U6BJ@28211|Alphaproteobacteria,1JZ7Y@119045|Methylobacteriaceae 28211|Alphaproteobacteria S TIGRFAM phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_87072_1 167548.EU98_1870 1.04e-89 275.0 COG0451@1|root,COG0451@2|Bacteria,1G44E@1117|Cyanobacteria 1117|Cyanobacteria M PFAM NAD-dependent epimerase dehydratase - - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd k59_13035_1 1381123.AYOD01000005_gene1273 1.79e-66 209.0 COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,2TU8N@28211|Alphaproteobacteria,43KT4@69277|Phyllobacteriaceae 28211|Alphaproteobacteria L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_71592_1 1245471.PCA10_28690 2.1e-06 53.9 2FJ35@1|root,34ATG@2|Bacteria,1P008@1224|Proteobacteria,1SW0Q@1236|Gammaproteobacteria,1YK4X@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_95711_2 1385658.U5KPZ6_9VIRU 2.1e-158 465.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_62403_2 1165094.RINTHH_3920 2.28e-18 84.7 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_212653_1 643867.Ftrac_0861 7.52e-13 74.7 COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,47JYW@768503|Cytophagia 976|Bacteroidetes O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 k59_96624_1 28365.G6P_BPPHL 3.66e-05 46.2 4QFJJ@10239|Viruses,4QUMJ@29258|ssDNA viruses,4QP4J@10860|Inoviridae 10860|Inoviridae S integral to membrane - - - - - - - - - - - - - k59_7263_1 521674.Plim_4263 3.42e-13 78.2 COG3941@1|root,COG5412@1|root,COG3941@2|Bacteria,COG5412@2|Bacteria,2J3JW@203682|Planctomycetes 203682|Planctomycetes S phage tail tape measure protein - - - - - - - - - - - - - k59_105495_2 946362.XP_004997549.1 5.68e-05 48.5 COG0553@1|root,KOG0387@2759|Eukaryota,38BYH@33154|Opisthokonta 33154|Opisthokonta KL transcription-coupled nucleotide-excision repair ERCC6L2 GO:0000302,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005815,GO:0005829,GO:0005856,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0015630,GO:0019899,GO:0019900,GO:0019901,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0034641,GO:0036297,GO:0042221,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0070887,GO:0071704,GO:0090304,GO:1901360,GO:1901700,GO:1901701 - ko:K20098 - - - - ko00000,ko01000,ko03400 - - - Helicase_C,SNF2_N,VIGSSK k59_114813_1 240016.ABIZ01000001_gene5053 4.95e-07 58.5 2DR7Z@1|root,33AM6@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_173455_2 1618248.A0A0C5IB82_9CIRC 1.62e-35 130.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_97150_3 1123487.KB892865_gene1394 1.58e-23 99.8 COG0749@1|root,COG0749@2|Bacteria,1MWX7@1224|Proteobacteria,2VMZW@28216|Betaproteobacteria 28216|Betaproteobacteria L DNA polymerase family A - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_63799_1 1123248.KB893348_gene222 1.46e-07 59.3 COG3210@1|root,COG3210@2|Bacteria,4PPRF@976|Bacteroidetes,1IZDI@117747|Sphingobacteriia 976|Bacteroidetes U Chaperone of endosialidase - - - - - - - - - - - - Peptidase_S74 k59_190066_1 233412.HD_1555 9.3e-55 187.0 COG4373@1|root,COG4373@2|Bacteria,1N2KG@1224|Proteobacteria,1RNKU@1236|Gammaproteobacteria,1Y827@135625|Pasteurellales 135625|Pasteurellales S Terminase-like family - - - - - - - - - - - - Terminase_6 k59_190066_10 339670.Bamb_2226 4.29e-17 88.6 COG3179@1|root,COG3179@2|Bacteria,1QXAI@1224|Proteobacteria,2VRGC@28216|Betaproteobacteria,1K5FP@119060|Burkholderiaceae 28216|Betaproteobacteria S chitinase - - - - - - - - - - - - - k59_254809_2 391589.RGAI101_2476 9.89e-10 61.2 COG0438@1|root,COG0438@2|Bacteria,1R9FR@1224|Proteobacteria,2U3H6@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Methyltransferase FkbM domain - - - - - - - - - - - - Methyltransf_21 k59_173459_1 1618260.A0A0C5I2C5_9CIRC 4.76e-15 75.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_131727_1 1475143.W8SNN0_9CIRC 1.6e-06 51.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_196924_2 1046627.BZARG_781 2.23e-30 111.0 COG3179@1|root,COG3179@2|Bacteria 2|Bacteria Q chitinase - - - - - - - - - - - - Peptidase_M15_4,Pesticin k59_181109_5 1120988.AXWV01000047_gene1101 0.000339 42.4 COG0451@1|root,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,1RNJD@1236|Gammaproteobacteria 1236|Gammaproteobacteria GJM Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides - - 4.1.1.35 ko:K08678 ko00520,ko01100,map00520,map01100 M00361 R01384 RC00508 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd k59_230892_1 1165094.RINTHH_3920 3.68e-35 134.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_254916_1 428125.CLOLEP_01411 1.15e-145 424.0 28J3N@1|root,2Z8ZU@2|Bacteria,1V15Z@1239|Firmicutes,249Z0@186801|Clostridia,3WNJZ@541000|Ruminococcaceae 186801|Clostridia S Phage portal protein - - - - - - - - - - - - Phage_portal k59_32680_2 202956.BBNL01000011_gene2402 6.68e-57 190.0 2CHRY@1|root,30Z9E@2|Bacteria,1RGQK@1224|Proteobacteria,1T1AM@1236|Gammaproteobacteria,3NKV5@468|Moraxellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - RecT k59_140283_2 438753.AZC_3585 1.55e-98 301.0 28IR7@1|root,2Z8QR@2|Bacteria,1PBTP@1224|Proteobacteria,2U248@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_98181_3 506534.Rhein_1689 8.05e-07 53.9 COG4122@1|root,COG4122@2|Bacteria,1NKWV@1224|Proteobacteria,1SP79@1236|Gammaproteobacteria,1X22H@135613|Chromatiales 135613|Chromatiales S Methyltransferase domain - - - - - - - - - - - - Methyltransf_24 k59_15667_2 1379709.S5TMV0_9CIRC 4.29e-72 225.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_256041_1 1609634.A0A0C5AFV4_9VIRU 1.1e-40 150.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_264929_4 1788454.A0A190WHE4_9CIRC 2.62e-16 84.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_106949_2 646529.Desaci_1279 4.14e-14 68.6 COG1591@1|root,COG1591@2|Bacteria,1V9FG@1239|Firmicutes 1239|Firmicutes L VRR_NUC - - - - - - - - - - - - VRR_NUC k59_58021_1 1116232.AHBF01000135_gene1983 4.2e-20 88.2 2EB9A@1|root,3359T@2|Bacteria,2INFV@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_165318_3 1234888.K0A2J2_9VIRU 2.62e-110 341.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_231915_1 1385658.U5KPZ6_9VIRU 1.96e-83 264.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_231915_2 1609634.A0A0C5ANA6_9VIRU 9.44e-09 59.7 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_74512_1 1692253.A0A0K1RLM4_9CIRC 1.13e-12 75.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_64969_1 1618248.A0A0C5IB82_9CIRC 6.66e-46 160.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_24077_2 1589297.A0A0B5H2N7_9CAUD 2.64e-19 90.9 4QAXA@10239|Viruses,4QQ1A@28883|Caudovirales,4QNU7@10744|Podoviridae 10744|Podoviridae S metallopeptidase activity - - - - - - - - - - - - - k59_182109_1 742740.HMPREF9474_02273 1.85e-05 47.4 2EAAT@1|root,334F2@2|Bacteria,1VJJI@1239|Firmicutes,24TQU@186801|Clostridia,223KD@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_182109_2 691965.D4P7C3_9CAUD 2.48e-31 114.0 4QDCX@10239|Viruses,4R0GS@35237|dsDNA viruses no RNA stage,4QS3P@28883|Caudovirales,4QKU8@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_182109_3 411460.RUMTOR_01352 2.63e-43 145.0 2AIHK@1|root,318ZG@2|Bacteria,1V7P0@1239|Firmicutes,24KNU@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_247509_1 1118055.CAGU01000029_gene20 1.55e-05 45.4 2E3AH@1|root,32YA0@2|Bacteria,1VGN7@1239|Firmicutes,25DV7@186801|Clostridia,22HSA@1570339|Peptoniphilaceae 186801|Clostridia S Protein of unknown function (DUF1064) - - - - - - - - - - - - DUF1064 k59_182198_1 641143.HMPREF9331_01272 9.48e-14 76.6 COG5410@1|root,COG5410@2|Bacteria,4NN30@976|Bacteroidetes,1ICKB@117743|Flavobacteriia,1EQE2@1016|Capnocytophaga 976|Bacteroidetes S Psort location Cytoplasmic, score 8.96 - - - - - - - - - - - - Terminase_6 k59_214545_1 488538.SAR116_0377 6.27e-109 332.0 COG4373@1|root,COG4373@2|Bacteria 2|Bacteria - - gp17a - - ko:K06909 - - - - ko00000 - - - Terminase_6,Terminase_6C k59_240620_1 1538804.A0A088F6T3_9CAUD 2.05e-130 401.0 4QAKM@10239|Viruses,4QPEF@28883|Caudovirales,4QKNE@10699|Siphoviridae 10699|Siphoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_240620_2 1517681.HW45_08080 5.32e-35 125.0 COG2131@1|root,COG2131@2|Bacteria,1RD1P@1224|Proteobacteria,1T01V@1236|Gammaproteobacteria,1Y2XW@135623|Vibrionales 135623|Vibrionales F MafB19-like deaminase - - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 k59_240620_3 1283300.ATXB01000001_gene214 1.21e-76 240.0 COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,1RPYV@1236|Gammaproteobacteria,1XEA2@135618|Methylococcales 135618|Methylococcales F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA - 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt k59_74802_1 649747.HMPREF0083_01035 7e-71 229.0 COG0270@1|root,COG0270@2|Bacteria,1TPNE@1239|Firmicutes,4HHQR@91061|Bacilli 91061|Bacilli H C-5 cytosine-specific DNA methylase - - - - - - - - - - - - DNA_methylase k59_99657_1 1122951.ATUE01000006_gene1033 1.22e-06 57.0 2EJXI@1|root,33DN6@2|Bacteria,1NKIP@1224|Proteobacteria,1SRVY@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_165995_2 1500301.JQMF01000003_gene4211 9.95e-90 277.0 29X6Q@1|root,30IVV@2|Bacteria,1QZEA@1224|Proteobacteria,2TY78@28211|Alphaproteobacteria,4B9JD@82115|Rhizobiaceae 28211|Alphaproteobacteria S RecT family - - - - - - - - - - - - RecT k59_207509_5 1611039.A0A0C5C3Z3_9CIRC 8.17e-19 86.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_49946_3 1234888.K0A2J2_9VIRU 2e-102 318.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_207510_2 1283076.M1IDA1_9CAUD 2.45e-20 92.4 4QAKW@10239|Viruses,4QX74@35237|dsDNA viruses no RNA stage,4QPSV@28883|Caudovirales,4QI33@10662|Myoviridae 10662|Myoviridae - - - GO:0005575,GO:0019012,GO:0044423,GO:0098015,GO:0098025 - - - - - - - - - - - k59_108040_1 1235661.K0IK58_9CAUD 2.3e-36 133.0 4QNC3@10744|Podoviridae 10744|Podoviridae S endonuclease activity - - - - - - - - - - - - - k59_91501_1 1121468.AUBR01000104_gene3117 8.21e-28 114.0 COG0863@1|root,COG0863@2|Bacteria,1TR56@1239|Firmicutes,248NR@186801|Clostridia 186801|Clostridia L Belongs to the N(4) N(6)-methyltransferase family cfr9IM - 2.1.1.113 ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_207583_1 1317124.DW2_14945 1.24e-05 52.8 COG1216@1|root,COG1216@2|Bacteria,1NE2P@1224|Proteobacteria,2V85T@28211|Alphaproteobacteria,2XNTT@285107|Thioclava 28211|Alphaproteobacteria S Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 k59_58323_1 1120934.KB894459_gene1381 3.26e-53 180.0 COG0639@1|root,COG0639@2|Bacteria,2GMS4@201174|Actinobacteria,4E9IG@85010|Pseudonocardiales 201174|Actinobacteria T Calcineurin-like phosphoesterase superfamily domain - - - - - - - - - - - - Metallophos,Metallophos_2 k59_41768_2 1038860.AXAP01000015_gene2060 1.15e-41 154.0 COG0741@1|root,COG0741@2|Bacteria,1MX5R@1224|Proteobacteria,2TVHC@28211|Alphaproteobacteria,3JUU6@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Transglycosylase SLT domain - - - - - - - - - - - - SLT k59_9368_2 460265.Mnod_6241 4.44e-18 82.0 2ABTE@1|root,3119Z@2|Bacteria,1NP1V@1224|Proteobacteria,2UKGX@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF4054) - - - - - - - - - - - - DUF4054 k59_174988_3 1173029.JH980292_gene811 1.84e-16 85.9 COG0860@1|root,COG0860@2|Bacteria,1G008@1117|Cyanobacteria,1H876@1150|Oscillatoriales 1117|Cyanobacteria M N-acetylmuramoyl-L-alanine amidase amiC - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - AMIN,Amidase_3 k59_174988_4 909613.UO65_0508 5.05e-08 63.9 COG0553@1|root,COG0553@2|Bacteria,2GISC@201174|Actinobacteria,4E0BN@85010|Pseudonocardiales 201174|Actinobacteria L SNF2 family N-terminal domain - - - - - - - - - - - - HHH_5,Helicase_C,SNF2_N k59_174988_6 469381.Dpep_0394 1.3e-10 63.5 COG0817@1|root,COG0817@2|Bacteria,3TCBE@508458|Synergistetes 508458|Synergistetes L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group - - - - - - - - - - - - - k59_9371_3 1154860.SAG0136_09230 1.88e-08 54.3 COG3339@1|root,COG3339@2|Bacteria 2|Bacteria S Protein of unknown function (DUF1232) XK27_09985 - - - - - - - - - - - DUF1232 k59_233200_1 1282360.ABAC460_19840 4.58e-33 127.0 COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria 1224|Proteobacteria C SMART Elongator protein 3 MiaB NifB - - - - - - - - - - - - B12-binding,Radical_SAM k59_108917_1 663610.JQKO01000006_gene2682 1.44e-11 75.5 COG1511@1|root,COG1511@2|Bacteria,1PENR@1224|Proteobacteria,2UDEI@28211|Alphaproteobacteria,3NC7W@45404|Beijerinckiaceae 28211|Alphaproteobacteria S domain protein - - - - - - - - - - - - - k59_133928_1 115417.EPrPW00000021059 0.00025 47.8 2CMYF@1|root,2QSRN@2759|Eukaryota,1MF2J@121069|Pythiales 121069|Pythiales T RAS protein activator like 1. Source PGD - - - - - - - - - - - - EGF_2,Peptidase_S74 k59_1378_1 1385658.U5KNR1_9VIRU 1.97e-18 91.7 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_1378_2 1234888.K0A2J2_9VIRU 2.24e-158 465.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_183536_1 1173762.S4TNV6_9CAUD 6.37e-41 149.0 4QGGR@10239|Viruses,4QZHR@35237|dsDNA viruses no RNA stage,4QUGZ@28883|Caudovirales,4QNY3@10744|Podoviridae 10744|Podoviridae S viral capsid - - - - - - - - - - - - - k59_167108_1 1215114.BBIU01000011_gene1684 1.1e-29 110.0 2DSAB@1|root,33F8C@2|Bacteria 2|Bacteria S Protein of unknown function (DUF3168) - - - - - - - - - - - - DUF3168 k59_191669_1 97137.C821_00055 9.42e-06 53.1 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1TSMG@1239|Firmicutes,4HBFH@91061|Bacilli,3F5CJ@33958|Lactobacillaceae 91061|Bacilli S Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C k59_200080_1 913970.F8RW82_9VIRU 9e-15 77.8 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_26216_3 1618259.A0A0C5I2B5_9CIRC 2.22e-53 184.0 4QE84@10239|Viruses,4QUKR@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_17432_1 95619.PM1_0224510 5.03e-07 62.8 COG2911@1|root,COG2931@1|root,COG2982@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria,COG2982@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q COG2931 RTX toxins and related Ca2 -binding proteins - - - - - - - - - - - - DUF4214,DUF4347,He_PIG,HemolysinCabind,PA14,VWA_2 k59_100642_1 1410619.SRDD_41940 1.5e-32 120.0 COG3108@1|root,COG3108@2|Bacteria,1RICX@1224|Proteobacteria,1S6D5@1236|Gammaproteobacteria,403YE@613|Serratia 1236|Gammaproteobacteria S D-alanyl-D-alanine carboxypeptidase - - - ko:K17733 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M15_4 k59_183539_1 1618248.A0A0C5IB82_9CIRC 7.35e-20 95.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_125678_1 1197951.I6RT34_9CAUD 3.51e-130 386.0 4QGAG@10239|Viruses,4R0KB@35237|dsDNA viruses no RNA stage,4QUA4@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_125678_2 979533.F1D0V0_9CAUD 5.12e-174 513.0 4QCM5@10239|Viruses,4QVZY@35237|dsDNA viruses no RNA stage,4QQFH@28883|Caudovirales,4QNDH@10744|Podoviridae 10744|Podoviridae S Bacteriophage head to tail connecting protein - GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019028,GO:0019058,GO:0019068,GO:0019072,GO:0019073,GO:0032991,GO:0044403,GO:0044419,GO:0044423,GO:0046798,GO:0051704 - - - - - - - - - - - k59_118383_2 102125.Xen7305DRAFT_00048600 2.72e-05 51.2 COG0582@1|root,COG0582@2|Bacteria,1G5GW@1117|Cyanobacteria,3VM75@52604|Pleurocapsales 1117|Cyanobacteria L Phage integrase family - - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_integrase k59_218005_1 652103.Rpdx1_2951 2.29e-60 213.0 COG3064@1|root,COG3064@2|Bacteria,1R6JV@1224|Proteobacteria,2U5NE@28211|Alphaproteobacteria,3JTDC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Membrane - - - - - - - - - - - - - k59_101381_2 1126950.G9J2B2_9CAUD 4.1e-259 736.0 4QBG0@10239|Viruses,4QWYZ@35237|dsDNA viruses no RNA stage,4QSGM@28883|Caudovirales,4QK1H@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_101381_3 1195072.M4HNM8_9CAUD 7.72e-20 84.3 4QFW3@10239|Viruses,4R0GR@35237|dsDNA viruses no RNA stage,4QS8R@28883|Caudovirales,4QI0I@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_18032_1 1609634.A0A0C5AFT2_9VIRU 8.62e-47 165.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_18032_3 1986029.Q9MBM7_9VIRU 2.47e-11 67.4 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_18032_4 105154.Q9MBU6_9VIRU 1.14e-87 276.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_68148_1 691965.D4P7I8_9CAUD 1.06e-42 147.0 4QGJH@10239|Viruses,4QZ35@35237|dsDNA viruses no RNA stage,4QRZS@28883|Caudovirales,4QMAA@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_68148_2 691965.D4P7I3_9CAUD 0.0 1466.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_68148_5 478749.BRYFOR_08565 2.03e-31 118.0 2A0KC@1|root,2ZGJK@2|Bacteria,1V2JS@1239|Firmicutes,24H6R@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_51766_1 1609634.A0A0C5AFV4_9VIRU 4.74e-207 592.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_250487_3 1234888.K0A2J2_9VIRU 1.33e-150 446.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_250487_5 105154.Q9MBU0_9VIRU 6.44e-27 114.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_159115_1 1458858.A0A088C4F9_9CAUD 0.00021 48.9 4QARC@10239|Viruses,4QV4E@35237|dsDNA viruses no RNA stage,4QPDS@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_159115_2 1192124.LIG30_2095 2.69e-06 50.1 COG0419@1|root,COG0419@2|Bacteria,1R4K4@1224|Proteobacteria,2VJVF@28216|Betaproteobacteria,1K5QE@119060|Burkholderiaceae 28216|Betaproteobacteria L AAA domain recF - - - - - - - - - - - AAA_23 k59_134762_1 691965.D4P7I3_9CAUD 2.01e-282 819.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_126572_4 1379701.JPJC01000229_gene2442 6.26e-22 92.8 2E3EW@1|root,33ISG@2|Bacteria,1MZ6T@1224|Proteobacteria,2UD2B@28211|Alphaproteobacteria,2K5R8@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - k59_126572_5 1408428.JNJP01000077_gene2795 7.11e-21 89.4 2BENR@1|root,328EB@2|Bacteria,1RHI2@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_126572_6 1298858.AUEL01000029_gene95 7.44e-55 199.0 COG1345@1|root,COG1345@2|Bacteria,1QZZ9@1224|Proteobacteria,2TZSX@28211|Alphaproteobacteria 28211|Alphaproteobacteria N Prophage tail length tape measure protein - - - - - - - - - - - - TMP_2 k59_18038_2 1379713.S5SYD9_9CIRC 2.51e-28 109.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_184193_1 1218352.B597_022235 1.5e-09 64.3 COG1196@1|root,COG5281@1|root,COG1196@2|Bacteria,COG5281@2|Bacteria,1MX2R@1224|Proteobacteria,1TAY6@1236|Gammaproteobacteria,1Z3JC@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria D tape measure protein - - - - - - - - - - - - - k59_126699_1 1234888.K0A2J2_9VIRU 5.66e-66 219.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_184282_2 1269813.ATUL01000006_gene1804 6.45e-18 87.8 COG1511@1|root,COG5281@1|root,COG1511@2|Bacteria,COG5281@2|Bacteria,1R1X9@1224|Proteobacteria 1224|Proteobacteria S domain protein - - - - - - - - - - - - - k59_168048_2 948071.S4S2D9_9CAUD 1.01e-255 724.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QNQ6@10744|Podoviridae 10744|Podoviridae S ribonucleoside-triphosphate reductase activity - - - - - - - - - - - - - k59_168048_5 194699.Q774Z7_BPBPP 1.77e-19 82.0 4QAZF@10239|Viruses,4QUTY@35237|dsDNA viruses no RNA stage,4QPH6@28883|Caudovirales,4QNEM@10744|Podoviridae 10744|Podoviridae S Protein of unknwon function (DUF3310) - - - - - - - - - - - - - k59_209014_2 1788439.A0A190WHD0_9CIRC 1.61e-16 84.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_175891_2 1609634.A0A0C5AFV4_9VIRU 3.41e-55 190.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_243151_3 1437882.AZRU01000081_gene6687 1.25e-38 147.0 28H75@1|root,2Z7JG@2|Bacteria,1MU3Y@1224|Proteobacteria,1S198@1236|Gammaproteobacteria,1YI2X@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Phage major capsid protein E - - - - - - - - - - - - Phage_cap_E k59_93806_1 35703.DQ02_13795 8.86e-37 132.0 COG3926@1|root,COG3926@2|Bacteria,1QV3R@1224|Proteobacteria,1T276@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Glycosyl hydrolase 108 - - - - - - - - - - - - CHAP k59_201872_1 1347392.CCEZ01000005_gene1217 2.08e-26 113.0 COG3378@1|root,COG4983@1|root,COG3378@2|Bacteria,COG4983@2|Bacteria,1TQP9@1239|Firmicutes,24AY6@186801|Clostridia,36FK1@31979|Clostridiaceae 186801|Clostridia S Phage plasmid primase, P4 family - - - ko:K06919 - - - - ko00000 - - - D5_N,Pox_D5,PriCT_1,Prim-Pol k59_3377_1 1692244.A0A0K1RLR5_9CIRC 1.61e-51 172.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_28303_4 1201293.AKXQ01000008_gene667 6.64e-19 88.2 COG4112@1|root,COG4112@2|Bacteria,1RG92@1224|Proteobacteria,1SUT3@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_28303_5 113395.AXAI01000008_gene916 2.58e-21 100.0 28IJH@1|root,31CGV@2|Bacteria,1NQ1X@1224|Proteobacteria,2UY53@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_44486_3 1121441.AUCX01000014_gene507 5.79e-15 87.4 COG5563@1|root,COG5563@2|Bacteria,1Q0JE@1224|Proteobacteria,430IH@68525|delta/epsilon subdivisions,2X0GF@28221|Deltaproteobacteria,2MD65@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_251233_1 2003327.CAPSD_BPCHP 1.82e-62 213.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_69257_1 1166948.JPZL01000002_gene1809 3.71e-45 159.0 COG3206@1|root,COG3206@2|Bacteria,1ND5H@1224|Proteobacteria,1RNXC@1236|Gammaproteobacteria 1236|Gammaproteobacteria M DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease - - - - - - - - - - - - Rad52_Rad22 k59_45810_1 444878.E3SR61_9CAUD 3.07e-62 208.0 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales 28883|Caudovirales S DnaB-like helicase C terminal domain - - - - - - - - - - - - - k59_129161_1 665956.HMPREF1032_00686 4.61e-23 105.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia,3WN92@541000|Ruminococcaceae 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_261370_1 1477404.A0A023NFX4_9CAUD 5.4e-48 179.0 4QAXA@10239|Viruses,4QYJI@35237|dsDNA viruses no RNA stage,4QQ1A@28883|Caudovirales,4QNU7@10744|Podoviridae 10744|Podoviridae S metallopeptidase activity - - - - - - - - - - - - - k59_153665_1 1123326.JFBL01000013_gene388 5.91e-12 70.5 COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,42M69@68525|delta/epsilon subdivisions,2YN4V@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA k59_54178_1 324057.Pjdr2_1602 0.000971 45.8 COG0863@1|root,COG0863@2|Bacteria,1TR56@1239|Firmicutes,4HHJ7@91061|Bacilli,2721R@186822|Paenibacillaceae 91061|Bacilli L DNA methylase - - 2.1.1.113 ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_178208_2 1692244.A0A0K1RLR5_9CIRC 1.95e-35 133.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_203234_1 691965.D4P7I3_9CAUD 1.2e-78 263.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_170341_1 1385658.U5KPZ6_9VIRU 9.87e-27 109.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_170341_3 1165094.RINTHH_3920 4.7e-51 176.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_220781_2 257310.BB2223 4.64e-08 55.5 2EJ14@1|root,33CSB@2|Bacteria,1NB37@1224|Proteobacteria,2VX0D@28216|Betaproteobacteria,3T8IE@506|Alcaligenaceae 28216|Betaproteobacteria S protein Mlr8012 SWALL Q984G8 (EMBL AP003013) (130 aa) fasta scores E() 6.8, 26.82 id in 123 aa - - - - - - - - - - - - - k59_220781_3 1357272.AVEO02000188_gene4472 3.97e-24 97.1 28RH4@1|root,2ZDW4@2|Bacteria,1RAWH@1224|Proteobacteria,1SR9N@1236|Gammaproteobacteria,1ZAGX@136849|Pseudomonas syringae group 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_29338_3 1574422.A0A0A1ENW9_9CIRC 2.73e-34 127.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_45833_1 1165094.RINTHH_3920 1.18e-22 96.7 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_220939_4 1042377.AFPJ01000009_gene166 3.47e-80 245.0 COG4508@1|root,COG4508@2|Bacteria,1RAX1@1224|Proteobacteria,1RYFG@1236|Gammaproteobacteria,465HS@72275|Alteromonadaceae 1236|Gammaproteobacteria S dUTPase dut - - - - - - - - - - - dUTPase_2 k59_220939_5 445686.E3SL93_9CAUD 6.6e-41 140.0 4QBKQ@10239|Viruses,4QVKF@35237|dsDNA viruses no RNA stage,4QQM7@28883|Caudovirales,4QIAS@10662|Myoviridae 10662|Myoviridae S Bacteriophage translational regulator - - - - - - - - - - - - - k59_220939_6 445696.E3SSZ5_9CAUD 3.24e-25 99.8 4QBC7@10239|Viruses,4QUQW@35237|dsDNA viruses no RNA stage,4QPGT@28883|Caudovirales,4QIH8@10662|Myoviridae 10662|Myoviridae S Pfam:Phage_clamp_A - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039686,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_5004_2 471874.PROSTU_03948 2.5e-70 228.0 COG0754@1|root,COG0754@2|Bacteria,1MW6V@1224|Proteobacteria,1RQAP@1236|Gammaproteobacteria,3Z8PZ@586|Providencia 1236|Gammaproteobacteria E Psort location Cytoplasmic, score 8.96 yjfC - - - - - - - - - - - GSP_synth k59_94946_1 1397528.Q671_14285 4.85e-67 214.0 COG4128@1|root,COG4128@2|Bacteria,1REHG@1224|Proteobacteria,1S491@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Zonular occludens toxin (Zot) - - - - - - - - - - - - Zot k59_261510_1 1237149.C900_05357 1.36e-44 164.0 COG1293@1|root,COG3941@1|root,COG1293@2|Bacteria,COG3941@2|Bacteria,4NS30@976|Bacteroidetes 976|Bacteroidetes D tape measure - - - - - - - - - - - - - k59_262730_1 1385658.U5KNR1_9VIRU 3.48e-26 108.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_262730_3 1609634.A0A0C5AFV4_9VIRU 1.08e-63 212.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_104806_1 1231377.C426_0595 1.2e-13 80.1 COG3378@1|root,COG3378@2|Bacteria,1UYRX@1239|Firmicutes,4HC06@91061|Bacilli,1YBFM@1357|Lactococcus 91061|Bacilli L DNA primase - - - ko:K06919 - - - - ko00000 - - - D5_N,Pox_D5,PriCT_1 k59_171848_1 1385658.U5KPZ6_9VIRU 6.14e-223 632.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_171848_3 1385658.U5KNR1_9VIRU 3.19e-23 100.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_55631_1 4956.XP_002496905.1 5.83e-13 74.3 COG1061@1|root,2QT4U@2759|Eukaryota,38GE0@33154|Opisthokonta,3NWXY@4751|Fungi,3QQHS@4890|Ascomycota,3RR67@4891|Saccharomycetes,3RYZM@4893|Saccharomycetaceae 4751|Fungi A Saccharomyces cerevisiae YDR332W irc3 GO:0000002,GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005739,GO:0005759,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0007005,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010467,GO:0010501,GO:0016043,GO:0016070,GO:0016072,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022613,GO:0031974,GO:0031981,GO:0032042,GO:0033676,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042623,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070035,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 - ko:K17677 - - - - ko00000,ko01000,ko03029 - - - Helicase_C,ResIII k59_236825_1 1105171.H2A0E8_9CAUD 1.26e-10 65.1 4QAKZ@10239|Viruses,4QYAE@35237|dsDNA viruses no RNA stage,4QPYH@28883|Caudovirales,4QM57@10699|Siphoviridae 10699|Siphoviridae S intein-mediated protein splicing - - - - - - - - - - - - - k59_195676_3 202954.BBNK01000004_gene2052 6.47e-21 86.7 2E4R2@1|root,32ZJM@2|Bacteria,1N9RQ@1224|Proteobacteria,1TNBD@1236|Gammaproteobacteria,3NQAF@468|Moraxellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_104941_3 742733.HMPREF9469_05011 4.5e-06 47.4 2BT3T@1|root,30VXX@2|Bacteria,1U239@1239|Firmicutes,25JN1@186801|Clostridia,2232Q@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_55636_2 391596.PBAL39_09216 0.000981 41.6 COG4675@1|root,COG4675@2|Bacteria,4P4J8@976|Bacteroidetes,1IYES@117747|Sphingobacteriia 976|Bacteroidetes S Phage Tail Collar Domain - - - - - - - - - - - - Collar k59_138752_2 490913.C4NTE2_9CAUD 1.94e-09 60.5 4QG5J@10239|Viruses,4QZ68@35237|dsDNA viruses no RNA stage,4QUEU@28883|Caudovirales,4QNKE@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_138752_3 1429767.W6AQX8_9CAUD 9.56e-74 264.0 4QFFI@10239|Viruses,4R00C@35237|dsDNA viruses no RNA stage,4QRHK@28883|Caudovirales,4QNX0@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_147679_2 29581.BW37_03941 1.14e-07 61.6 COG2963@1|root,COG2963@2|Bacteria,1PCWW@1224|Proteobacteria,2VKXF@28216|Betaproteobacteria,47377@75682|Oxalobacteraceae 28216|Betaproteobacteria L transposase activity - - - - - - - - - - - - - k59_179736_2 264462.Bd3266 0.000643 50.8 COG3210@1|root,COG3210@2|Bacteria,1NED3@1224|Proteobacteria,42WDX@68525|delta/epsilon subdivisions,2MTVC@213481|Bdellovibrionales,2WRDH@28221|Deltaproteobacteria 213481|Bdellovibrionales U cell wall surface anchor family protein - - - - - - - - - - - - Peptidase_S74 k59_229565_8 1120705.FG95_03711 1.31e-39 139.0 2AUXR@1|root,2ZBPW@2|Bacteria,1RAID@1224|Proteobacteria,2U6KV@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_56801_1 1055815.AYYA01000051_gene1349 6.6e-88 259.0 COG0454@1|root,COG0456@2|Bacteria,1NKHK@1224|Proteobacteria,1SCR2@1236|Gammaproteobacteria,3NN7A@468|Moraxellaceae 1236|Gammaproteobacteria K Acetyltransferase (GNAT) domain - - - - - - - - - - - - DUF3749 k59_131727_2 1379707.S5T672_9CIRC 2.75e-33 130.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_56916_2 1122176.KB903543_gene601 4.84e-25 105.0 COG0305@1|root,COG1372@1|root,COG0305@2|Bacteria,COG1372@2|Bacteria,4NF8P@976|Bacteroidetes,1IPIQ@117747|Sphingobacteriia 976|Bacteroidetes L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_14446_1 2003327.CAPSD_BPCHP 1.32e-29 125.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_237932_1 394.NGR_c11420 2.28e-05 53.9 COG1409@1|root,COG1409@2|Bacteria 2|Bacteria S acid phosphatase activity - - - - - - - - - - - - Big_5,Collagen,Peptidase_S74 k59_49191_2 94624.Bpet1366 1.93e-109 331.0 COG3969@1|root,COG3969@2|Bacteria,1NBDM@1224|Proteobacteria,2W88H@28216|Betaproteobacteria,3T675@506|Alcaligenaceae 28216|Betaproteobacteria S Domain of unknown function (DUF3440) - - - - - - - - - - - - DUF3440,PAPS_reduct k59_148959_2 1207055.C100_20610 3.78e-05 46.2 COG1396@1|root,COG1396@2|Bacteria,1N6TH@1224|Proteobacteria,2U85N@28211|Alphaproteobacteria,2KAXF@204457|Sphingomonadales 204457|Sphingomonadales K Cro/C1-type HTH DNA-binding domain - - - - - - - - - - - - - k59_148959_3 10752.A0MZC9_BPN4 6.85e-51 193.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_148959_4 1122201.AUAZ01000017_gene2947 3.87e-40 150.0 COG0749@1|root,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,465DD@72275|Alteromonadaceae 1236|Gammaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity - - - - - - - - - - - - DNA_pol_A k59_190067_2 1210884.HG799464_gene10908 1.5e-45 163.0 COG0175@1|root,COG0175@2|Bacteria 2|Bacteria EH sulfate reduction - - - - - - - - - - - - PAPS_reduct k59_81145_1 1211777.BN77_4165 1.8e-106 322.0 COG1783@1|root,COG1783@2|Bacteria,1R66A@1224|Proteobacteria,2TV42@28211|Alphaproteobacteria,4BHJY@82115|Rhizobiaceae 28211|Alphaproteobacteria S Phage terminase large subunit - - - ko:K06909 - - - - ko00000 - - - Terminase_3 k59_106102_1 1121459.AQXE01000001_gene2739 1.67e-35 137.0 COG5410@1|root,COG5410@2|Bacteria,1N0W2@1224|Proteobacteria,42YNM@68525|delta/epsilon subdivisions,2WU2R@28221|Deltaproteobacteria,2MAIS@213115|Desulfovibrionales 28221|Deltaproteobacteria K chromosome segregation - - - - - - - - - - - - - k59_49201_2 679201.HMPREF9334_00370 1.41e-17 82.8 COG0175@1|root,COG0175@2|Bacteria,1TSMI@1239|Firmicutes,4H2P8@909932|Negativicutes 909932|Negativicutes EH Phosphoadenosine phosphosulfate reductase family - - - - - - - - - - - - PAPS_reduct k59_32537_1 1564096.A0A0A0YS25_9CAUD 5.1e-23 102.0 4QDKY@10239|Viruses,4QTV7@28883|Caudovirales,4QJ57@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_196822_1 1122931.AUAE01000001_gene741 2.53e-09 63.2 COG0358@1|root,COG0358@2|Bacteria,4NENT@976|Bacteroidetes,2FMV1@200643|Bacteroidia,22WQI@171551|Porphyromonadaceae 976|Bacteroidetes L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 k59_14453_2 598467.BrE312_2692 2.34e-20 86.7 2DISD@1|root,32UBM@2|Bacteria,1MZ73@1224|Proteobacteria,1SA29@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_8079_1 1618251.A0A0C5I2L8_9CIRC 4.18e-35 136.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_123655_1 1385658.U5KPZ6_9VIRU 1.14e-81 262.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_182274_1 1692257.A0A0K1RL39_9CIRC 4.1e-22 99.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_98385_1 43989.cce_1126 1.96e-25 104.0 COG2856@1|root,COG3093@1|root,COG2856@2|Bacteria,COG3093@2|Bacteria,1G3K4@1117|Cyanobacteria,3KI7N@43988|Cyanothece 1117|Cyanobacteria K Pfam:DUF955 - - - ko:K18831 - - - - ko00000,ko02048,ko03000 - - - HTH_3,Peptidase_M78 k59_165468_1 1357714.A0A067XQP7_9CAUD 5.63e-37 138.0 4QAJD@10239|Viruses,4QW4M@35237|dsDNA viruses no RNA stage,4QQ7U@28883|Caudovirales,4QIAP@10662|Myoviridae 10662|Myoviridae S gp32 DNA binding protein like - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039686,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_214613_1 279383.Q5DN38_9CAUD 2.79e-40 147.0 4QFB4@10239|Viruses,4QZ8P@35237|dsDNA viruses no RNA stage,4QSGK@28883|Caudovirales,4QKUP@10699|Siphoviridae 10699|Siphoviridae S viral capsid - - - - - - - - - - - - - k59_239472_1 1220717.L7TND1_9VIRU 6.22e-17 87.0 4QAK6@10239|Viruses 10239|Viruses S N-acetylmuramoyl-L-alanine amidase activity - GO:0005575,GO:0018995,GO:0019012,GO:0030430,GO:0033643,GO:0033646,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_165471_1 652103.Rpdx1_2942 8.93e-72 236.0 28S81@1|root,2ZEJD@2|Bacteria,1RCNN@1224|Proteobacteria,2U6Z0@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_82548_1 78245.Xaut_3032 6.14e-57 188.0 COG0175@1|root,COG0175@2|Bacteria,1QZJ1@1224|Proteobacteria,2U233@28211|Alphaproteobacteria 28211|Alphaproteobacteria EH sulfate reduction - - - - - - - - - - - - - k59_239474_1 1156844.KB891852_gene3730 5.12e-05 50.8 COG3740@1|root,COG3740@2|Bacteria 2|Bacteria OU Phage prohead protease, HK97 family - - - ko:K06904 - - - - ko00000 - - - Peptidase_S78,Phage_capsid k59_40778_1 1618250.A0A0C5I9W8_9CIRC 1.45e-08 61.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_24318_2 1156919.QWC_12603 2.07e-13 72.8 COG0741@1|root,COG0741@2|Bacteria,1N5XK@1224|Proteobacteria 1224|Proteobacteria M lytic transglycosylase activity - - - ko:K02395 - - - - ko00000,ko02035 - - - - k59_98407_1 927677.ALVU02000001_gene4243 2.4e-46 163.0 COG0582@1|root,COG0582@2|Bacteria,1G0M1@1117|Cyanobacteria,1H6MC@1142|Synechocystis 1117|Cyanobacteria L phage integrase family - - - - - - - - - - - - - k59_40787_1 679189.HMPREF9019_0917 1.13e-49 162.0 COG0756@1|root,COG0756@2|Bacteria,4NNI4@976|Bacteroidetes 2|Bacteria F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA dut GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23,4.1.1.36,6.3.2.5 ko:K01520,ko:K13038 ko00240,ko00770,ko00983,ko01100,map00240,map00770,map00983,map01100 M00053,M00120 R02100,R03269,R04231,R11896 RC00002,RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase k59_198513_20 1472716.KBK24_0121465 2.54e-42 149.0 COG2214@1|root,COG2214@2|Bacteria,1N1HS@1224|Proteobacteria,2W2UD@28216|Betaproteobacteria,1KA00@119060|Burkholderiaceae 28216|Betaproteobacteria O DnaJ molecular chaperone homology domain - - - - - - - - - - - - - k59_285_15 1121937.AUHJ01000007_gene1915 5.62e-14 69.7 2BW73@1|root,2ZHHX@2|Bacteria,1P6PK@1224|Proteobacteria,1SVI5@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_285_34 1150626.PHAMO_340068 6.61e-17 94.7 COG4675@1|root,COG4675@2|Bacteria,1N0FZ@1224|Proteobacteria,2UDXB@28211|Alphaproteobacteria,2JZKF@204441|Rhodospirillales 204441|Rhodospirillales S Phage Tail Collar Domain - - - - - - - - - - - - Collar k59_33588_1 558169.AGAV01000006_gene1206 2.96e-12 75.5 COG1061@1|root,COG4951@1|root,COG1061@2|Bacteria,COG4951@2|Bacteria,1TS5R@1239|Firmicutes,4HCVA@91061|Bacilli 91061|Bacilli L Type III restriction protein res subunit XK27_08510 - - - - - - - - - - - Helicase_C,ResIII k59_232603_2 10704.B4UTY5_BP163 9.31e-20 87.8 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_33590_1 1692252.A0A0K1RL35_9CIRC 9.52e-49 167.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_401_2 1788454.A0A190WHE4_9CIRC 1.58e-31 119.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_91628_1 1609634.A0A0C5ANA6_9VIRU 8.72e-15 78.2 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_50050_1 759914.BP951000_1469 2.27e-40 154.0 COG5283@1|root,COG5283@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - PhageMin_Tail k59_50050_9 1355374.JARU01000019_gene1937 9.25e-20 101.0 COG1215@1|root,COG1215@2|Bacteria,1QVA7@1224|Proteobacteria 1224|Proteobacteria M Glycosyl transferase, family 2 exoO - - ko:K12983,ko:K12988,ko:K16555,ko:K16564,ko:K19354 - - - - ko00000,ko01000,ko01003,ko01005 - GT2 - Glycos_transf_2 k59_50050_14 633131.TR2A62_1181 7.93e-13 72.0 COG0500@1|root,COG0500@2|Bacteria,1RIQB@1224|Proteobacteria,2U356@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q methyltransferase - - - - - - - - - - - - Methyltransf_23 k59_50050_17 533240.CRC_02915 2.06e-46 167.0 COG1086@1|root,COG1086@2|Bacteria,1G63C@1117|Cyanobacteria,1HMR1@1161|Nostocales 1117|Cyanobacteria M Polysaccharide biosynthesis protein - - 4.2.1.115,5.1.3.2 ko:K15894,ko:K17716 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00362 R00291,R09697 RC00289,RC02609 ko00000,ko00001,ko00002,ko01000 - - - Polysacc_synt_2 k59_50050_23 1166018.FAES_4010 2.86e-17 90.9 COG1372@1|root,COG1372@2|Bacteria,4P3TC@976|Bacteroidetes,47V1Q@768503|Cytophagia 976|Bacteroidetes L Participates in initiation and elongation during chromosome replication - - - - - - - - - - - - - k59_50050_38 1327982.S0A2L1_9CAUD 1.73e-117 348.0 4QAIJ@10239|Viruses,4QVZ9@35237|dsDNA viruses no RNA stage,4QPXI@28883|Caudovirales,4QM02@10699|Siphoviridae 10699|Siphoviridae S C-5 cytosine-specific DNA methylase - - - - - - - - - - - - - k59_50050_41 867903.ThesuDRAFT_02222 4.28e-44 174.0 COG3378@1|root,COG5519@1|root,COG3378@2|Bacteria,COG5519@2|Bacteria,1TQP9@1239|Firmicutes,24AY6@186801|Clostridia 186801|Clostridia L Phage plasmid primase, P4 family - - - ko:K06919 - - - - ko00000 - - - D5_N,Pox_D5,PriCT_1,Prim-Pol k59_50050_42 1041826.FCOL_05440 1.84e-49 166.0 COG0270@1|root,COG0270@2|Bacteria,4P351@976|Bacteroidetes,1I9UJ@117743|Flavobacteriia,2NZ0G@237|Flavobacterium 976|Bacteroidetes L C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_225342_3 395493.BegalDRAFT_0944 2.54e-13 78.6 COG0433@1|root,COG0433@2|Bacteria,1NE29@1224|Proteobacteria,1T4BP@1236|Gammaproteobacteria 2|Bacteria S PFAM Zonular occludens toxin (Zot) - - - ko:K06915 - - - - ko00000 - - - Zot k59_158670_1 1548905.A0A0A1IWZ4_9CAUD 2.69e-110 337.0 4QAKM@10239|Viruses,4QPEF@28883|Caudovirales,4QKNE@10699|Siphoviridae 10699|Siphoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_250036_1 1609634.A0A0C5AFT2_9VIRU 1.07e-30 117.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_17624_1 1609634.A0A0C5ANA6_9VIRU 2.68e-11 67.0 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_183667_1 1618247.A0A0C5IMK7_9CIRC 4.99e-09 60.8 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_150794_2 680198.SCAB_32881 2.53e-19 90.9 2EB9A@1|root,3359T@2|Bacteria,2INFV@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_150794_3 679201.HMPREF9334_01066 1.78e-20 91.3 COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,4H2DZ@909932|Negativicutes 909932|Negativicutes E Belongs to the UPF0758 family radC - - ko:K03630 - - - - ko00000 - - - RadC k59_76079_1 316275.VSAL_I1045 4.17e-18 97.4 COG5301@1|root,COG5301@2|Bacteria,1N4KH@1224|Proteobacteria,1RXZU@1236|Gammaproteobacteria,1XW3K@135623|Vibrionales 135623|Vibrionales S Phage tail-collar fibre protein - - - - - - - - - - - - DUF3751 k59_142537_1 179237.Q8W6K4_9CAUD 7.69e-78 269.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales 28883|Caudovirales S N-acetylmuramoyl-L-alanine amidase activity - - - - - - - - - - - - - k59_134184_2 1618248.A0A0C5IB82_9CIRC 3.82e-14 75.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_200275_1 1609634.A0A0C5AFV4_9VIRU 5.73e-142 418.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_200275_2 1609634.A0A0C5ANA6_9VIRU 2.67e-41 147.0 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_200275_5 1609634.A0A0C5AFT2_9VIRU 2.24e-148 427.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_200275_7 1609634.A0A0C5AFV4_9VIRU 2.42e-117 352.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_191830_2 571166.KI421509_gene1131 6.97e-22 95.9 COG3914@1|root,COG3914@2|Bacteria,1RC2I@1224|Proteobacteria,2U5BE@28211|Alphaproteobacteria 28211|Alphaproteobacteria O O-linked N-acetylglucosamine transferase SPINDLY family - - - - - - - - - - - - - k59_142619_2 547228.M4ZS05_9CAUD 1.28e-06 55.8 4QB6U@10239|Viruses,4QUPZ@35237|dsDNA viruses no RNA stage,4QQRQ@28883|Caudovirales,4QKMH@10699|Siphoviridae 10699|Siphoviridae S Terminase small subunit - - - - - - - - - - - - - k59_142619_6 717774.Marme_1832 1.85e-25 103.0 COG0741@1|root,COG0741@2|Bacteria,1QZ7X@1224|Proteobacteria,1T417@1236|Gammaproteobacteria 1236|Gammaproteobacteria M lytic transglycosylase activity - - - - - - - - - - - - - k59_109210_1 279238.Saro_2997 1.87e-35 135.0 2C8Q6@1|root,2Z882@2|Bacteria,1PY18@1224|Proteobacteria 1224|Proteobacteria S Phage stabilisation protein - - - - - - - - - - - - Phage_stabilise k59_76160_5 338966.Ppro_0057 1.55e-48 169.0 KOG1584@1|root,32BW5@2|Bacteria,1PW91@1224|Proteobacteria,42YNQ@68525|delta/epsilon subdivisions,2WTQC@28221|Deltaproteobacteria 28221|Deltaproteobacteria H Sulfotransferase domain - - - - - - - - - - - - Sulfotransfer_1 k59_76160_6 648757.Rvan_3315 2.64e-121 369.0 COG5323@1|root,COG5323@2|Bacteria,1MW8S@1224|Proteobacteria,2TREI@28211|Alphaproteobacteria,3N62D@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_3,Terminase_6,Terminase_6C k59_118986_1 347834.RHE_CH01097 2.24e-61 199.0 28NGF@1|root,2ZBII@2|Bacteria,1R9KY@1224|Proteobacteria,2U1P7@28211|Alphaproteobacteria,4B747@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_259679_1 1618254.A0A0C5IBG4_9CIRC 1.37e-124 362.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_110206_1 1101190.ARWB01000001_gene616 9.88e-22 91.7 COG1917@1|root,COG1917@2|Bacteria,1N6Q0@1224|Proteobacteria,2UKI2@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Cupin 2, conserved barrel domain protein - - - - - - - - - - - - - k59_259811_1 1234888.K0A2J2_9VIRU 1.85e-24 102.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_84886_2 342113.DM82_4348 5.28e-29 117.0 COG0749@1|root,COG0749@2|Bacteria,1P27P@1224|Proteobacteria 1224|Proteobacteria L DNA polymerase family A - - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - DNA_pol_A k59_135358_1 1173022.Cri9333_0392 1.19e-11 66.6 COG4474@1|root,COG4474@2|Bacteria,1GA9B@1117|Cyanobacteria,1HGRT@1150|Oscillatoriales 1117|Cyanobacteria S Protein of unknown function (DUF1273) - - - - - - - - - - - - DUF1273 k59_242757_2 1477404.A0A023NGI3_9CAUD 3.73e-125 373.0 4QEFX@10239|Viruses,4QYYG@35237|dsDNA viruses no RNA stage,4QRRV@28883|Caudovirales,4QNTK@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_2834_1 1986029.Q9MBM3_9VIRU 3.02e-39 146.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_2834_3 105154.Q9MBU6_9VIRU 2.22e-195 564.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_27636_1 345341.KUTG_05496 2.58e-14 79.0 COG0507@1|root,COG0507@2|Bacteria,2GJRK@201174|Actinobacteria,4DXGE@85010|Pseudonocardiales 201174|Actinobacteria L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity - - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 k59_152024_2 1379722.S5SY31_9CIRC 1.88e-69 218.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_184762_3 742766.HMPREF9455_03134 2.97e-16 75.9 2AEBE@1|root,3145V@2|Bacteria,4NZAM@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - k59_135360_1 1406780.U5PZT1_9CAUD 1.13e-19 90.1 4QEFX@10239|Viruses,4QYYG@35237|dsDNA viruses no RNA stage,4QRRV@28883|Caudovirales,4QNTK@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_135360_2 655097.C8ZKI5_9CAUD 2.27e-30 115.0 4QGM6@10239|Viruses,4QYNV@35237|dsDNA viruses no RNA stage,4QRH4@28883|Caudovirales,4QP0P@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_234185_2 476272.RUMHYD_01966 1.67e-18 78.6 2EK5K@1|root,33DW0@2|Bacteria,1UU54@1239|Firmicutes,255II@186801|Clostridia 186801|Clostridia S Putative phage holin Dp-1 - - - - - - - - - - - - Phage_holin_Dp1 k59_209340_1 1126411.I1TEL3_9CIRC 4.16e-19 89.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_84888_2 1379712.S5TMV9_9CIRC 6.13e-40 154.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_168584_1 765913.ThidrDRAFT_2489 1.37e-52 184.0 COG0582@1|root,COG0582@2|Bacteria,1QB64@1224|Proteobacteria,1S8Y0@1236|Gammaproteobacteria,1X12F@135613|Chromatiales 135613|Chromatiales L Belongs to the 'phage' integrase family - - - - - - - - - - - - - k59_45112_2 759938.F5BSB4_9CIRC 2.91e-46 167.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_53585_1 1385658.U5KPZ6_9VIRU 3.22e-57 192.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_202524_1 1692249.A0A0K1RLN8_9CIRC 2.26e-33 127.0 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_160782_1 136084.Q9G0H1_9CAUD 1.94e-21 98.2 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales,4QNBW@10744|Podoviridae 10744|Podoviridae S DNA helicase activity - - - - - - - - - - - - - k59_11341_4 1304877.KI519399_gene5021 1.58e-184 536.0 COG5362@1|root,COG5362@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Terminase_6C k59_210229_4 1408254.T458_20835 1.8e-14 75.9 COG4675@1|root,COG4675@2|Bacteria,1VHKQ@1239|Firmicutes,4HVG0@91061|Bacilli,26XMT@186822|Paenibacillaceae 91061|Bacilli S Phage Tail Collar Domain mdpB - - - - - - - - - - - Collar k59_28805_1 310539.Q5G7P7_9CAUD 1.01e-07 57.8 4QGB5@10239|Viruses,4QXR2@35237|dsDNA viruses no RNA stage,4QSQD@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_28805_2 90371.CY43_09840 5.23e-15 80.1 2DBI5@1|root,2Z9EN@2|Bacteria,1PMHG@1224|Proteobacteria,1RQE1@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Exodeoxyribonuclease VIII - - - ko:K10906 - - - - ko00000,ko01000,ko03400 - - - DUF3799 k59_128439_2 1122222.AXWR01000013_gene972 3.27e-27 114.0 COG0399@1|root,COG0399@2|Bacteria,1WJBP@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus E pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis - - - - - - - - - - - - DegT_DnrJ_EryC1 k59_60984_1 488538.SAR116_0377 2.65e-24 102.0 COG4373@1|root,COG4373@2|Bacteria 2|Bacteria - - gp17a - - ko:K06909 - - - - ko00000 - - - Terminase_6,Terminase_6C k59_185879_1 529929.B3FYJ5_9CAUD 3.36e-31 127.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_227541_2 1618254.A0A0C5IBG4_9CIRC 3.02e-78 243.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_146567_1 1385658.U5KPZ6_9VIRU 1.55e-76 245.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_5481_2 145579.CAPSD_BPPHM 2.61e-43 166.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_228983_1 1618247.A0A0C5IMK7_9CIRC 8.39e-11 68.2 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_236201_3 1313301.AUGC01000010_gene921 2.08e-14 75.9 COG0468@1|root,COG0468@2|Bacteria,4NEXT@976|Bacteroidetes 976|Bacteroidetes L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA - - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA k59_37564_1 78898.MVEG_05265T0 3.14e-16 91.7 COG1241@1|root,KOG0480@2759|Eukaryota,38B9W@33154|Opisthokonta,3NWN6@4751|Fungi 4751|Fungi L MCM OB domain - - - - - - - - - - - - MCM,MCM_OB k59_37564_3 1229909.NSED_07620 4.22e-12 62.4 arCOG08662@1|root,arCOG08662@2157|Archaea 1229909.NSED_07620|- - - - - - - - - - - - - - - - k59_95486_1 2003327.CAPSD_BPCHP 3.88e-96 306.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_179020_1 935261.JAGL01000009_gene1177 6.4e-22 103.0 COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1QT52@1224|Proteobacteria,2TVNI@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Toprim-like - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - DnaB_C,Toprim_2 k59_121415_1 1220601.L7TLW2_9CAUD 2.36e-178 537.0 4QASG@10239|Viruses,4QZZU@35237|dsDNA viruses no RNA stage,4QT37@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_137884_1 1609634.A0A0C5AFV4_9VIRU 2.86e-56 198.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_228986_4 1609634.A0A0C5AFV4_9VIRU 2.44e-42 161.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_221724_1 105154.Q9MBU3_9VIRU 2.49e-09 60.8 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_146749_2 1215114.BBIU01000011_gene1684 8.92e-29 108.0 2DSAB@1|root,33F8C@2|Bacteria 2|Bacteria S Protein of unknown function (DUF3168) - - - - - - - - - - - - DUF3168 k59_182458_1 563192.HMPREF0179_03434 4.77e-100 320.0 28IA2@1|root,2Z8CQ@2|Bacteria,1PQM2@1224|Proteobacteria,42Y9U@68525|delta/epsilon subdivisions,2WTUC@28221|Deltaproteobacteria,2MARZ@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_124421_2 1463926.JOCA01000001_gene4386 3.36e-09 59.3 COG3757@1|root,COG3757@2|Bacteria,2GKS0@201174|Actinobacteria 201174|Actinobacteria M lysozyme - - - - - - - - - - - - Glyco_hydro_25 k59_149295_2 717774.Marme_4207 2.83e-17 78.6 COG3772@1|root,COG3772@2|Bacteria,1N0ZQ@1224|Proteobacteria,1S9AE@1236|Gammaproteobacteria 1236|Gammaproteobacteria S lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_24914_2 186617.M9M8L2_9VIRU 1.16e-75 247.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_24915_1 69279.BG36_20875 2.43e-69 230.0 COG1783@1|root,COG4373@1|root,COG1783@2|Bacteria,COG4373@2|Bacteria,1PE12@1224|Proteobacteria,2V9EC@28211|Alphaproteobacteria,43QJZ@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Mu-like prophage FluMu protein gp28 - - - - - - - - - - - - - k59_257124_2 649831.L083_3123 3.78e-68 233.0 COG0399@1|root,COG0500@1|root,COG0399@2|Bacteria,COG0500@2|Bacteria,2GKD7@201174|Actinobacteria,4DCEX@85008|Micromonosporales 201174|Actinobacteria E Belongs to the DegT DnrJ EryC1 family - - 2.6.1.106 ko:K13310,ko:K16436 ko00523,ko01055,ko01130,map00523,map01055,map01130 M00797,M00800,M00803 R06426,R06631,R08928 RC00006,RC01514,RC03347 ko00000,ko00001,ko00002,ko01000 - - - DegT_DnrJ_EryC1 k59_24922_1 1385658.U5KPZ6_9VIRU 1.65e-108 333.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_175051_2 1041826.FCOL_05440 3.92e-61 196.0 COG0270@1|root,COG0270@2|Bacteria,4P351@976|Bacteroidetes,1I9UJ@117743|Flavobacteriia,2NZ0G@237|Flavobacterium 976|Bacteroidetes L C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_59175_1 755178.Cyan10605_3427 3.45e-06 56.6 COG1674@1|root,COG1674@2|Bacteria,1G2BT@1117|Cyanobacteria 1117|Cyanobacteria D DNA segregation ATPase FtsK SpoIIIE - - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - DNA_pol_A_exo1,FtsK_SpoIIIE,PDDEXK_1 k59_9414_1 1340810.V5UT29_9CAUD 0.000423 48.9 4QGTC@10239|Viruses,4QW5X@35237|dsDNA viruses no RNA stage,4QRPJ@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_92584_1 1609634.A0A0C5AFV4_9VIRU 4.93e-30 122.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_67630_1 1127515.H9C0H6_9CAUD 3.63e-36 148.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QI9F@10662|Myoviridae 10662|Myoviridae S Type III restriction enzyme, res subunit - - - - - - - - - - - - - k59_26428_1 1165094.RINTHH_3920 3.53e-51 177.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_26428_3 105154.Q9MBU6_9VIRU 1.37e-212 607.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_26428_5 105154.Q9MBU3_9VIRU 6.37e-21 93.2 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_258616_2 866536.Belba_2819 1.7e-12 77.8 COG0358@1|root,COG5545@1|root,COG0358@2|Bacteria,COG5545@2|Bacteria,4NETK@976|Bacteroidetes,47NER@768503|Cytophagia 976|Bacteroidetes L Protein of unknown function (DUF3987) - - - - - - - - - - - - DUF3987,PriCT_2,VirE_N k59_93380_1 10752.A0MZD9_BPN4 2.33e-52 184.0 4QEQT@10239|Viruses,4QYJH@35237|dsDNA viruses no RNA stage,4QQ1B@28883|Caudovirales,4QNPW@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_259707_1 561180.BIFGAL_04130 1.77e-18 89.4 COG0675@1|root,COG0675@2|Bacteria,2GM6K@201174|Actinobacteria,4D2K6@85004|Bifidobacteriales 201174|Actinobacteria L Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon k59_68593_2 1524467.IV04_20380 1.3e-96 296.0 COG0863@1|root,COG0863@2|Bacteria,1MY4G@1224|Proteobacteria,1RQHA@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.113,2.1.1.72 ko:K00571,ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_259713_2 234267.Acid_6941 2.54e-13 74.7 COG3064@1|root,COG4627@1|root,COG3064@2|Bacteria,COG4627@2|Bacteria 2|Bacteria M translation initiation factor activity - - - ko:K08307,ko:K19140 - - - - ko00000,ko01000,ko01011,ko02048 - - - DDE_Tnp_1,DUF772,Methyltransf_11 k59_27537_1 1458357.BG58_33085 2.59e-15 86.3 COG5283@1|root,COG5283@2|Bacteria,1R5FU@1224|Proteobacteria,2VPNW@28216|Betaproteobacteria,1K6D9@119060|Burkholderiaceae 28216|Betaproteobacteria D tape measure - - - - - - - - - - - - - k59_135276_1 375286.mma_2192 5.8e-29 127.0 2ES6Y@1|root,33JRQ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_159636_1 1986029.Q9MBM3_9VIRU 1.78e-06 57.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_10341_1 742740.HMPREF9474_01234 2.41e-33 135.0 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,2487V@186801|Clostridia,221Y2@1506553|Lachnoclostridium 186801|Clostridia L COG COG0749 DNA polymerase I - 3-5 exonuclease and polymerase domains - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_242680_2 160488.PP_2268 2.15e-30 112.0 2E0FP@1|root,32W1T@2|Bacteria,1NCZR@1224|Proteobacteria 1224|Proteobacteria L Phage endonuclease I - - - - - - - - - - - - Phage_endo_I k59_250760_1 1297865.APJD01000009_gene2699 3.86e-06 52.8 COG1216@1|root,COG1216@2|Bacteria,1NM61@1224|Proteobacteria,2TRZB@28211|Alphaproteobacteria,3K08D@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Glycosyltransferase like family 2 - - - ko:K07011 - - - - ko00000 - - - Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2 k59_201467_2 313628.LNTAR_02789 1.72e-07 54.3 COG0758@1|root,COG0758@2|Bacteria 2|Bacteria LU DNA mediated transformation smf - - ko:K04096 - - - - ko00000 - - - DNA_processg_A,DUF2493,MoCo_carrier k59_201467_3 1391647.AVSV01000017_gene675 4.27e-09 59.7 COG1525@1|root,COG1525@2|Bacteria,1VASF@1239|Firmicutes,24G14@186801|Clostridia,36I19@31979|Clostridiaceae 186801|Clostridia L Staphylococcal nuclease homologues - - 3.1.31.1 ko:K01174 - - - - ko00000,ko01000 - - - Ada_Zn_binding,Cu_amine_oxidN1,SNase k59_35589_1 1219035.NT2_13_00580 3.67e-32 132.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_52478_1 657322.FPR_04500 1.65e-08 54.7 2C5R4@1|root,33HN0@2|Bacteria,1VPDJ@1239|Firmicutes,24MSZ@186801|Clostridia 186801|Clostridia S Transposon-encoded protein TnpV - - - - - - - - - - - - TnpV k59_52478_2 314230.DSM3645_28042 7.26e-06 49.3 COG0827@1|root,COG4646@1|root,COG0827@2|Bacteria,COG4646@2|Bacteria,2J1PH@203682|Planctomycetes 203682|Planctomycetes L Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair - - - - - - - - - - - - - k59_135372_4 1234888.K0A2J2_9VIRU 6.18e-103 325.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_127274_1 1340829.S5Y5F0_9CAUD 5.75e-12 72.0 4QNA2@10699|Siphoviridae 10699|Siphoviridae S AAA domain - - - - - - - - - - - - - k59_128758_1 1120746.CCNL01000014_gene2086 6.49e-11 67.8 COG2887@1|root,COG2887@2|Bacteria 2|Bacteria L Belongs to the helicase family. UvrD subfamily - - - - - - - - - - - - DUF2800 k59_85993_1 1336243.JAEA01000002_gene2654 9.59e-11 64.3 COG4696@1|root,COG4696@2|Bacteria,1NMJC@1224|Proteobacteria,2VGV1@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - - k59_103232_4 425104.Ssed_2465 1.21e-25 115.0 COG0582@1|root,COG0582@2|Bacteria,1MVZB@1224|Proteobacteria,1RP4Y@1236|Gammaproteobacteria,2QBQ9@267890|Shewanellaceae 1236|Gammaproteobacteria L Belongs to the 'phage' integrase family intR - - ko:K14059 - - - - ko00000 - - - Arm-DNA-bind_2,Phage_integrase k59_178058_1 1123288.SOV_2c10450 2.38e-113 336.0 COG0863@1|root,COG0863@2|Bacteria,1UZIN@1239|Firmicutes,4H3N6@909932|Negativicutes 909932|Negativicutes L DNA methylase - - - - - - - - - - - - N6_N4_Mtase k59_227959_1 645099.MREP_BBTVA 2.84e-07 57.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_235363_1 1385658.U5KPZ6_9VIRU 1.18e-166 486.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_261238_1 1122201.AUAZ01000017_gene2962 3.64e-13 77.8 COG4675@1|root,COG4675@2|Bacteria 2|Bacteria M tail collar domain protein - - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - Collar,Phage_fiber_2 k59_210581_1 1234888.K0A2J2_9VIRU 2.25e-91 285.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_85996_2 40215.BBOS01000001_gene727 1.07e-11 74.7 COG0454@1|root,COG1040@1|root,COG0456@2|Bacteria,COG1040@2|Bacteria,1QV41@1224|Proteobacteria,1RSAP@1236|Gammaproteobacteria,3NM26@468|Moraxellaceae 1236|Gammaproteobacteria K acetyltransferase - - - - - - - - - - - - - k59_170190_1 202956.BBNL01000011_gene2401 1.93e-09 60.1 COG5377@1|root,COG5377@2|Bacteria,1MWP8@1224|Proteobacteria,1RN9Q@1236|Gammaproteobacteria,3NIHJ@468|Moraxellaceae 1236|Gammaproteobacteria L YqaJ-like viral recombinase domain - - - - - - - - - - - - YqaJ k59_94678_1 1498172.A0A0F6N5T0_9CAUD 4.21e-25 106.0 4QAIK@10239|Viruses,4QPEB@28883|Caudovirales,4QP3P@10744|Podoviridae 10744|Podoviridae S phosphoprotein phosphatase activity - - - - - - - - - - - - - k59_136807_1 652103.Rpdx1_2951 2.3e-69 233.0 COG3064@1|root,COG3064@2|Bacteria,1R6JV@1224|Proteobacteria,2U5NE@28211|Alphaproteobacteria,3JTDC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Membrane - - - - - - - - - - - - - k59_211968_1 1161935.H9D1F0_9CAUD 2.08e-10 62.8 4QFN3@10239|Viruses,4QZSZ@35237|dsDNA viruses no RNA stage,4QQ4M@28883|Caudovirales,4QNXC@10744|Podoviridae 10744|Podoviridae S exonuclease activity - - - - - - - - - - - - - k59_222382_2 1408452.JAGZ01000001_gene3188 0.000431 47.4 2B6CU@1|root,31ZAI@2|Bacteria,2H1WU@201174|Actinobacteria,23D8Z@1762|Mycobacteriaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_236692_4 1385658.U5KPZ6_9VIRU 1.58e-174 510.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_171829_1 938709.AUSH02000023_gene1941 7.99e-38 138.0 294MN@1|root,2ZS13@2|Bacteria,4P817@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - k59_195533_2 1219049.SP5_068_00880 1.08e-112 342.0 COG0827@1|root,COG0827@2|Bacteria,1R5Y7@1224|Proteobacteria,2VEZS@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Domain of unknown function (DUF4942) - - - - - - - - - - - - DUF4942,MTS k59_147483_1 77856.REP_BFDV 8.49e-14 75.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_55451_7 1609634.A0A0C5AFV4_9VIRU 2.04e-190 551.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_113954_1 759938.F5BSB4_9CIRC 6.24e-13 73.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_155337_2 1165094.RINTHH_3920 3.96e-18 84.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_155342_1 1121896.JMLU01000002_gene437 0.000587 50.1 COG3291@1|root,COG4935@1|root,COG3291@2|Bacteria,COG4935@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia,2NU73@237|Flavobacterium 976|Bacteroidetes O C-terminal domain of CHU protein family - - - - - - - - - - - - CHU_C,HYR,SprB k59_254734_1 1556290.A0A0A0RM00_9CAUD 3.7e-07 52.8 4QAXQ@10239|Viruses,4QRFY@28883|Caudovirales,4QM52@10699|Siphoviridae 10699|Siphoviridae S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor - - - - - - - - - - - - - k59_123731_1 272134.KB731324_gene2190 4.88e-05 50.8 COG0419@1|root,COG1196@1|root,COG0419@2|Bacteria,COG1196@2|Bacteria 2|Bacteria D nuclear chromosome segregation - - 2.7.11.1 ko:K03546,ko:K12132 - - - - ko00000,ko01000,ko01001,ko03400 - - - AAA_23,SMC_N k59_264211_2 691965.D4P7I0_9CAUD 1.66e-57 191.0 4QDSZ@10239|Viruses,4QXJ8@35237|dsDNA viruses no RNA stage,4QPKE@28883|Caudovirales,4QM8R@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_254888_2 261292.Nit79A3_2432 6.52e-15 76.3 COG0237@1|root,COG0237@2|Bacteria,1Q0GP@1224|Proteobacteria,2WC82@28216|Betaproteobacteria,374F8@32003|Nitrosomonadales 28216|Betaproteobacteria H dephospho-CoA kinase activity - - - - - - - - - - - - - k59_254888_3 163164.WD_0262 8.81e-09 55.5 COG0817@1|root,COG0817@2|Bacteria,1RCYK@1224|Proteobacteria,2U727@28211|Alphaproteobacteria,47GB1@766|Rickettsiales 766|Rickettsiales L genomic island protein Bartonella henselae str. Houston-1 gi 49238285 emb CAF27499.1 and to - - - - - - - - - - - - - k59_156642_1 1380394.JADL01000006_gene5249 3.12e-21 105.0 28QU5@1|root,2ZD9H@2|Bacteria,1RAU8@1224|Proteobacteria,2VC6Q@28211|Alphaproteobacteria,2JY0A@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - k59_97236_2 96561.Dole_0006 3.69e-22 100.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,42M7X@68525|delta/epsilon subdivisions,2WJCA@28221|Deltaproteobacteria,2MHKJ@213118|Desulfobacterales 28221|Deltaproteobacteria L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_246492_1 1548905.A0A0A1IVS6_9CAUD 1.03e-41 156.0 4QAQ9@10239|Viruses,4QPTV@28883|Caudovirales,4QKRS@10699|Siphoviridae 10699|Siphoviridae S Putative phage tail protein - GO:0005575,GO:0008150,GO:0016032,GO:0018995,GO:0019012,GO:0019058,GO:0019062,GO:0022610,GO:0030430,GO:0033643,GO:0033646,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044403,GO:0044406,GO:0044419,GO:0044650,GO:0051704 - - - - - - - - - - - k59_149032_1 1226994.AMZB01000079_gene96 5.9e-06 54.3 2CZBU@1|root,32T60@2|Bacteria,1N7TC@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_190172_1 290512.Paes_0859 2.09e-40 140.0 COG0302@1|root,COG0302@2|Bacteria,1FD81@1090|Chlorobi 1090|Chlorobi F PFAM GTP cyclohydrolase I folE - 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydroI k59_131828_1 1219035.NT2_13_00600 4.18e-52 177.0 290X3@1|root,2ZNIW@2|Bacteria,1P7TA@1224|Proteobacteria,2UXFQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_106174_3 10689.H9C0B6_BPCPT 1.42e-08 58.9 4QAIJ@10239|Viruses,4QVZ9@35237|dsDNA viruses no RNA stage,4QPXI@28883|Caudovirales 28883|Caudovirales S C-5 cytosine-specific DNA methylase - - - - - - - - - - - - - k59_107545_6 1609634.A0A0C5AFV4_9VIRU 2.19e-127 389.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_65944_1 2003327.CAPSD_BPCHP 3.21e-79 257.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_240239_1 279238.Saro_2694 4.96e-110 320.0 COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,2TU8N@28211|Alphaproteobacteria,2K409@204457|Sphingomonadales 204457|Sphingomonadales L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_89875_1 177437.HRM2_00020 3.87e-15 75.1 COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,42M7M@68525|delta/epsilon subdivisions,2WJ9X@28221|Deltaproteobacteria,2MHSK@213118|Desulfobacterales 28221|Deltaproteobacteria L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB - 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim k59_265078_1 1692244.A0A0K1RLR5_9CIRC 3.6e-43 150.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_265078_2 1618248.A0A0C5IB82_9CIRC 9.2e-30 117.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_107567_1 180332.JTGN01000026_gene1584 4.44e-05 51.2 COG1196@1|root,COG1572@1|root,COG3209@1|root,COG3210@1|root,COG5434@1|root,COG1196@2|Bacteria,COG1572@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG5434@2|Bacteria 2|Bacteria M polygalacturonase activity - - 3.2.1.97 ko:K02004,ko:K17624,ko:K20951,ko:K20952,ko:K21493 ko05111,map05111 M00258 - - ko00000,ko00001,ko00002,ko01000,ko02000,ko02048 3.A.1 GH101 - F5_F8_type_C,FIVAR,Glyco_hydro_28,LRR_5,Laminin_G_3 k59_90827_1 633149.Bresu_1398 0.000832 49.7 2DSRK@1|root,33H6U@2|Bacteria,1P21N@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_90831_1 335992.SAR11_0539 5.39e-09 58.9 COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1R7DJ@1224|Proteobacteria,2VF2S@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - - - - - - - - - - CTP_transf_like,PfkB k59_265259_2 1692249.A0A0K1RLN8_9CIRC 9.35e-13 70.5 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_116583_3 1385658.U5KNR1_9VIRU 5.72e-46 162.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_75173_1 1157943.KB892705_gene2039 2.21e-73 234.0 COG3969@1|root,COG3969@2|Bacteria,2H4MT@201174|Actinobacteria 201174|Actinobacteria S Phosphoadenosine phosphosulfate reductase family - - - - - - - - - - - - PAPS_reduct k59_91737_1 755178.Cyan10605_2107 3.93e-31 118.0 COG0270@1|root,COG0270@2|Bacteria,1G138@1117|Cyanobacteria 1117|Cyanobacteria H PFAM C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_16983_1 35703.DQ02_13760 1.12e-24 99.8 COG4570@1|root,COG4570@2|Bacteria,1RH5J@1224|Proteobacteria,1S7I6@1236|Gammaproteobacteria 1236|Gammaproteobacteria L endodeoxyribonuclease RusA - - - - - - - - - - - - RusA k59_116699_4 1123508.JH636442_gene4425 3.06e-48 158.0 2CCFB@1|root,32RVJ@2|Bacteria 2|Bacteria S zinc-finger-containing domain - - - - - - - - - - - - DUF3268 k59_66911_1 1235659.S4T8W6_9CAUD 1.74e-21 94.0 4QAPV@10239|Viruses,4QYKD@35237|dsDNA viruses no RNA stage,4QQ0U@28883|Caudovirales,4QHZK@10662|Myoviridae 10662|Myoviridae S regulation of transcription, DNA-dependent - - - - - - - - - - - - - k59_166450_1 669008.D3W681_9CAUD 2.97e-28 116.0 4QBMV@10239|Viruses,4QUU6@35237|dsDNA viruses no RNA stage,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_108344_1 105154.Q9MBU6_9VIRU 1.34e-77 251.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_75270_1 395963.Bind_2744 5.7e-09 60.1 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2TRJF@28211|Alphaproteobacteria,3NACC@45404|Beijerinckiaceae 28211|Alphaproteobacteria L DNA polymerase A domain polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_42052_1 1379717.S5SY19_9CIRC 2.32e-47 168.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_83476_2 472175.EL18_01354 1.43e-10 65.1 COG0438@1|root,COG0438@2|Bacteria,1PJ7G@1224|Proteobacteria,2U2TC@28211|Alphaproteobacteria,43Q7F@69277|Phyllobacteriaceae 28211|Alphaproteobacteria M Methyltransferase domain - - - - - - - - - - - - Methyltransf_25 k59_58603_2 768066.HELO_2633 7.05e-36 142.0 COG0542@1|root,COG4733@1|root,COG0542@2|Bacteria,COG4733@2|Bacteria,1PGW5@1224|Proteobacteria,1TCGB@1236|Gammaproteobacteria,1XQ94@135619|Oceanospirillales 135619|Oceanospirillales O response to heat - - - - - - - - - - - - - k59_58605_2 1618248.A0A0C5IB82_9CIRC 1.7e-10 63.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_643_3 1034101.G1D1G4_9CAUD 1.25e-82 261.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales 28883|Caudovirales S N-methyltransferase activity - - - - - - - - - - - - - k59_125973_1 1609634.A0A0C5AFV4_9VIRU 3.09e-74 241.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_100910_1 1204521.I7A8M7_9CAUD 5.03e-104 331.0 4QCZC@10239|Viruses,4QX3V@35237|dsDNA viruses no RNA stage,4QRH3@28883|Caudovirales,4QHVR@10662|Myoviridae 10662|Myoviridae S Bacterial DNA polymerase III alpha subunit - - - - - - - - - - - - - k59_51216_2 1123501.KB902299_gene3814 9.55e-20 88.6 COG3108@1|root,COG3108@2|Bacteria,1QDAN@1224|Proteobacteria,2TV1K@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Bacterial protein of unknown function (DUF882) - - - - - - - - - - - - Peptidase_M15_3 k59_42944_2 580332.Slit_1922 5.58e-39 152.0 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1NKZK@1224|Proteobacteria,2VM59@28216|Betaproteobacteria 28216|Betaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_125976_1 648885.KB316282_gene1384 6.09e-08 59.7 2CC8M@1|root,308VJ@2|Bacteria,1R789@1224|Proteobacteria,2U2NB@28211|Alphaproteobacteria,1JW8K@119045|Methylobacteriaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_241797_2 1692252.A0A0K1RL35_9CIRC 2.46e-90 278.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_225405_1 522373.Smlt1886 8.32e-20 94.4 COG3378@1|root,COG3378@2|Bacteria,1MV7I@1224|Proteobacteria,1RRN5@1236|Gammaproteobacteria,1X4S3@135614|Xanthomonadales 135614|Xanthomonadales S D5 N terminal like - - - ko:K06919 - - - - ko00000 - - - D5_N,Pox_D5 k59_250069_2 69328.PVLB_09335 2.78e-23 99.0 COG3206@1|root,COG3206@2|Bacteria,1ND5H@1224|Proteobacteria,1RNXC@1236|Gammaproteobacteria 1236|Gammaproteobacteria M DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease - - - - - - - - - - - - Rad52_Rad22 k59_67774_2 1618259.A0A0C5I2B5_9CIRC 9.92e-41 145.0 4QE84@10239|Viruses,4QUKR@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_67774_3 1618247.A0A0C5IMK7_9CIRC 1.11e-09 65.5 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_117816_4 742740.HMPREF9474_02273 0.000151 49.7 2EAAT@1|root,334F2@2|Bacteria,1VJJI@1239|Firmicutes,24TQU@186801|Clostridia,223KD@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_117816_5 691965.D4P7C5_9CAUD 0.0 951.0 4QBV3@10239|Viruses,4QW0W@35237|dsDNA viruses no RNA stage,4QPPJ@28883|Caudovirales,4QKW5@10699|Siphoviridae 10699|Siphoviridae S Phage Terminase - - - - - - - - - - - - - k59_117816_6 691965.D4P7D3_9CAUD 2.72e-155 453.0 4QAYV@10239|Viruses,4QUZ7@35237|dsDNA viruses no RNA stage,4QPU3@28883|Caudovirales,4QKKX@10699|Siphoviridae 10699|Siphoviridae S Phage portal protein - - - - - - - - - - - - - k59_117816_7 691965.D4P7D6_9CAUD 2.42e-168 507.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_117816_8 478749.BRYFOR_08520 3.49e-25 98.2 2E2Y0@1|root,32XYV@2|Bacteria,1VD9S@1239|Firmicutes,24PK0@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_117816_10 742733.HMPREF9469_05026 2.16e-36 129.0 28NM4@1|root,2ZBMQ@2|Bacteria,1V1QD@1239|Firmicutes,24G1B@186801|Clostridia,221N8@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_76234_1 1609634.A0A0C5AFT2_9VIRU 4.11e-86 264.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_167504_4 580331.Thit_1378 1.96e-42 163.0 COG5283@1|root,COG5412@1|root,COG5283@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,247QT@186801|Clostridia,42GRZ@68295|Thermoanaerobacterales 186801|Clostridia N tail tape measure protein TP901 core region - - - - - - - - - - - - PhageMin_Tail k59_43634_27 224719.Abm4_1676 1.6e-70 249.0 COG1199@1|root,arCOG00770@2157|Archaea,2XSWZ@28890|Euryarchaeota,23NV7@183925|Methanobacteria 183925|Methanobacteria L HELICc2 - - - - - - - - - - - - DEAD_2,Helicase_C_2,ResIII k59_43634_35 1189612.A33Q_3767 3.76e-13 73.6 COG1948@1|root,COG1948@2|Bacteria,4P5FR@976|Bacteroidetes,47W39@768503|Cytophagia 976|Bacteroidetes L ERCC4 domain - - - - - - - - - - - - ERCC4,HHH_5 k59_43634_38 765914.ThisiDRAFT_2068 1.41e-28 121.0 COG1573@1|root,COG3210@1|root,COG1573@2|Bacteria,COG3210@2|Bacteria,1MWX1@1224|Proteobacteria,1S2U7@1236|Gammaproteobacteria,1WWN0@135613|Chromatiales 135613|Chromatiales L TIGRFAM Phage SPO1 DNA polymerase-related protein - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k59_43634_55 317936.Nos7107_2133 9.99e-09 62.8 COG3409@1|root,COG3409@2|Bacteria,1GIYB@1117|Cyanobacteria,1HT7U@1161|Nostocales 1117|Cyanobacteria M Putative peptidoglycan binding domain - - - - - - - - - - - - PG_binding_1 k59_18435_1 314271.RB2654_16481 5.61e-39 156.0 COG0616@1|root,COG0740@1|root,COG0616@2|Bacteria,COG0740@2|Bacteria,1MUQ9@1224|Proteobacteria,2TX6D@28211|Alphaproteobacteria 28211|Alphaproteobacteria OU Belongs to the peptidase S14 family - - - - - - - - - - - - CLP_protease,Mu-like_gpT k59_151864_1 1692250.A0A0K1RLR1_9CIRC 1.89e-128 374.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_27473_1 1121028.ARQE01000006_gene4535 4.04e-15 77.0 28HHC@1|root,2Z7T2@2|Bacteria,1PZ57@1224|Proteobacteria,2U3R2@28211|Alphaproteobacteria 28211|Alphaproteobacteria S AAA domain - - - - - - - - - - - - AAA_24 k59_218480_1 1192868.CAIU01000008_gene937 2.11e-62 205.0 COG0863@1|root,COG0863@2|Bacteria,1NQ2A@1224|Proteobacteria,2UJ12@28211|Alphaproteobacteria,43KMC@69277|Phyllobacteriaceae 28211|Alphaproteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - - - - - - - - - - - N6_N4_Mtase k59_218481_1 865937.Gilli_1074 3.33e-06 49.7 COG0451@1|root,COG0451@2|Bacteria,4NDV4@976|Bacteroidetes,1HYF4@117743|Flavobacteriia,2P77G@244698|Gillisia 976|Bacteroidetes GM Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction fcl - 1.1.1.271 ko:K02377 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R05692 RC01014 ko00000,ko00001,ko01000 - - - Epimerase k59_218481_2 886293.Sinac_5882 7.86e-43 151.0 COG1089@1|root,COG1089@2|Bacteria,2IWZ4@203682|Planctomycetes 203682|Planctomycetes M Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose gmd - 4.2.1.47 ko:K01711 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R00888 RC00402 ko00000,ko00001,ko01000 - - - GDP_Man_Dehyd k59_101824_1 1385658.U5KPZ6_9VIRU 9.02e-102 315.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_68545_2 627192.SLG_22000 2.95e-84 263.0 COG1783@1|root,COG1783@2|Bacteria,1R66A@1224|Proteobacteria,2TV42@28211|Alphaproteobacteria,2K7D4@204457|Sphingomonadales 204457|Sphingomonadales S TIGRFAM phage terminase, large subunit, PBSX family - - - ko:K06909 - - - - ko00000 - - - Terminase_3 k59_143663_3 1961.JOAK01000020_gene7320 1.52e-07 53.5 COG3864@1|root,COG3864@2|Bacteria,2GWVA@201174|Actinobacteria 201174|Actinobacteria S VWA-like domain (DUF2201) - - - - - - - - - - - - DUF2201,DUF2201_N k59_119788_1 856793.MICA_280 4.5e-31 129.0 COG3378@1|root,COG4951@1|root,COG3378@2|Bacteria,COG4951@2|Bacteria,1MV7I@1224|Proteobacteria,2TRS2@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Phage plasmid primase P4 family - - - ko:K06919 - - - - ko00000 - - - D5_N,Pox_D5 k59_144976_1 1165094.RINTHH_3920 2.85e-53 179.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_36261_8 1122939.ATUD01000001_gene222 0.000253 42.7 2E3V5@1|root,32JJK@2|Bacteria,2HPIX@201174|Actinobacteria,4CQWE@84995|Rubrobacteria 84995|Rubrobacteria - - - - - - - - - - - - - - - k59_234878_1 1150398.JIBJ01000011_gene2316 2.21e-27 110.0 arCOG05626@1|root,2Z9D9@2|Bacteria,2IIAB@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_19344_3 1120963.KB894514_gene389 2.43e-52 192.0 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1NKZK@1224|Proteobacteria,1S4YH@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C k59_19344_4 49964.Q94MS4_9CAUD 1.68e-144 443.0 4QCUF@10239|Viruses,4QV7U@35237|dsDNA viruses no RNA stage,4QQ89@28883|Caudovirales,4QNCY@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_19344_8 49964.Q94MS1_9CAUD 1.76e-130 381.0 4QB4H@10239|Viruses,4QYQI@35237|dsDNA viruses no RNA stage,4QUAR@28883|Caudovirales,4QNUV@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_3950_3 1538804.A0A088F7W8_9CAUD 3.92e-109 327.0 4QAR1@10239|Viruses,4QPJE@28883|Caudovirales 28883|Caudovirales S ATPase activity - - - - - - - - - - - - - k59_119941_1 697282.Mettu_1302 2.08e-86 269.0 COG0535@1|root,COG0535@2|Bacteria,1PHAQ@1224|Proteobacteria 1224|Proteobacteria C Radical SAM - - - - - - - - - - - - Fer4_14,Radical_SAM,SPASM k59_53591_3 1609634.A0A0C5ANA6_9VIRU 6.42e-17 84.3 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_86534_1 882.DVU_2153 1.33e-13 81.3 COG4733@1|root,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria,42QDD@68525|delta/epsilon subdivisions,2WIU9@28221|Deltaproteobacteria,2MEC5@213115|Desulfovibrionales 28221|Deltaproteobacteria S Phage-related protein, tail - - - - - - - - - - - - Phage-tail_3 k59_137676_2 670252.C8CLI5_9CAUD 1.01e-50 196.0 4QCM6@10239|Viruses,4QVAQ@35237|dsDNA viruses no RNA stage,4QPVV@28883|Caudovirales,4QNID@10744|Podoviridae 10744|Podoviridae S actin binding - - - - - - - - - - - - - k59_137676_3 1220714.L7TMV1_9CAUD 3.27e-64 211.0 4QEFV@10239|Viruses,4QYS7@35237|dsDNA viruses no RNA stage,4QRRT@28883|Caudovirales,4QJVQ@10662|Myoviridae 10662|Myoviridae S Pfam:Terminase_3C - - - - - - - - - - - - - k59_12615_2 1385658.U5KPZ6_9VIRU 9.65e-88 279.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_5442_4 698761.RTCIAT899_CH08255 1.24e-12 70.5 COG3772@1|root,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,2U8JK@28211|Alphaproteobacteria,4BFHW@82115|Rhizobiaceae 28211|Alphaproteobacteria G Phage lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_221506_1 1267535.KB906767_gene3625 2.23e-23 102.0 COG5545@1|root,COG5545@2|Bacteria,3Y6U4@57723|Acidobacteria 57723|Acidobacteria S Domain of unknown function (DUF3854) - - - - - - - - - - - - DUF3854,VirE k59_178840_1 525282.HMPREF0391_11498 1.74e-08 59.7 COG0420@1|root,COG0420@2|Bacteria,1TXJV@1239|Firmicutes,24DM3@186801|Clostridia,22IEC@1570339|Peptoniphilaceae 186801|Clostridia L Calcineurin-like phosphoesterase superfamily domain - - - ko:K03546 - - - - ko00000,ko03400 - - - Metallophos,Metallophos_2 k59_187199_1 504472.Slin_1577 8.62e-12 68.2 2DC6Z@1|root,2ZD43@2|Bacteria 2|Bacteria S HNH endonuclease - - - - - - - - - - - - HNH_3 k59_146525_1 565045.NOR51B_2137 4.54e-05 46.6 COG2827@1|root,COG2827@2|Bacteria 2|Bacteria L Endonuclease containing a URI domain yhbQ GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - ko:K07461 - - - - ko00000 - - - GIY-YIG k59_252831_2 292414.TM1040_0794 2.9e-10 65.9 COG0640@1|root,COG0640@2|Bacteria 2|Bacteria K DNA-binding transcription factor activity - - - ko:K19505,ko:K21885 - - - - ko00000,ko03000 - - - Fic,Fic_N,GTP_EFTU,HTH_36,RP-C,RP-C_C,SelB-wing_3 k59_79177_1 756272.Plabr_0241 1.34e-104 315.0 COG0639@1|root,COG0639@2|Bacteria 2|Bacteria T phosphoprotein phosphatase activity - - 3.1.3.16 ko:K07313 - - - - ko00000,ko01000 - - - Metallophos,Metallophos_2 k59_46621_1 504728.K649_11105 3.57e-17 87.8 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1WIA1@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,Taq-exonuc k59_194860_1 1120941.AUBL01000026_gene2 2.58e-39 148.0 COG2304@1|root,COG2304@2|Bacteria,2HMJ4@201174|Actinobacteria,4D74C@85005|Actinomycetales 201174|Actinobacteria S TROVE domain - - - - - - - - - - - - TROVE k59_171060_1 102129.Lepto7375DRAFT_7301 1.44e-05 52.0 COG3941@1|root,COG4678@1|root,COG3941@2|Bacteria,COG4678@2|Bacteria,1G8BM@1117|Cyanobacteria,1HHG8@1150|Oscillatoriales 1117|Cyanobacteria G Muramidase (Phage lambda lysozyme) - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - - k59_228793_2 105154.Q9MBU6_9VIRU 2.67e-62 208.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_71054_1 1449058.JQKT01000007_gene1824 1.3e-15 77.0 COG0207@1|root,COG0207@2|Bacteria,2GKY0@201174|Actinobacteria,4FN07@85023|Microbacteriaceae 201174|Actinobacteria F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009125,GO:0009129,GO:0009130,GO:0009131,GO:0009157,GO:0009159,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009178,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0032259,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042083,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046073,GO:0046078,GO:0046079,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt k59_46623_1 403905.A7J284_9CAUD 2.53e-25 111.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_37420_2 906668.G8C7I3_9CAUD 1.38e-163 479.0 4QBV3@10239|Viruses,4QW0W@35237|dsDNA viruses no RNA stage,4QPPJ@28883|Caudovirales,4QKW5@10699|Siphoviridae 10699|Siphoviridae S Phage Terminase - - - - - - - - - - - - - k59_194862_1 592031.GCWU000322_00507 5.45e-13 68.9 COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,24HF0@186801|Clostridia,25W7R@186806|Eubacteriaceae 186801|Clostridia F Psort location Cytoplasmic, score comEB - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 k59_13802_1 469596.HMPREF9488_03270 1.47e-14 72.4 COG0758@1|root,COG0758@2|Bacteria,1VNFT@1239|Firmicutes 1239|Firmicutes LU Protein of unknown function (DUF2493) - - - - - - - - - - - - DUF2493 k59_13802_2 717785.HYPMC_1235 2.01e-26 111.0 COG1783@1|root,COG1783@2|Bacteria,1MVJB@1224|Proteobacteria,2U2BM@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6 k59_139351_1 1414739.W6AT15_9CAUD 4.02e-161 473.0 4QAXX@10239|Viruses,4QV9W@35237|dsDNA viruses no RNA stage,4QPTB@28883|Caudovirales,4QMAG@10699|Siphoviridae 10699|Siphoviridae S Phage terminase large subunit (GpA) - GO:0005575,GO:0008150,GO:0016032,GO:0018995,GO:0019058,GO:0019068,GO:0019072,GO:0019073,GO:0030430,GO:0032991,GO:0033643,GO:0033646,GO:0043493,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044403,GO:0044419,GO:0051704,GO:0098009,GO:1902494,GO:1904949 - - - - - - - - - - - k59_172614_1 1788447.A0A190WHJ9_9CIRC 6.42e-60 197.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_212604_1 2003327.CAPSD_BPCHP 2.77e-74 242.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_245780_2 1156919.QWC_12603 4.01e-15 84.7 COG0741@1|root,COG0741@2|Bacteria,1N5XK@1224|Proteobacteria 1224|Proteobacteria M lytic transglycosylase activity - - - ko:K02395 - - - - ko00000,ko02035 - - - - k59_48281_1 742727.HMPREF9447_01719 9.32e-32 121.0 COG1032@1|root,COG1032@2|Bacteria,4NZ46@976|Bacteroidetes,2FNXU@200643|Bacteroidia,4APA0@815|Bacteroidaceae 976|Bacteroidetes C radical SAM domain protein - - - - - - - - - - - - - k59_48281_2 1279017.AQYJ01000017_gene1398 3.99e-10 58.5 COG0582@1|root,COG0582@2|Bacteria 2|Bacteria L DNA integration - - - - - - - - - - - - Phage_int_SAM_4,Phage_integrase k59_245782_1 360910.BAV0432 1.29e-74 251.0 COG3170@1|root,COG3170@2|Bacteria,1Q45C@1224|Proteobacteria,2W196@28216|Betaproteobacteria 28216|Betaproteobacteria NU Tfp pilus assembly protein FimV - - - - - - - - - - - - - k59_48284_1 105154.Q9MBU6_9VIRU 9.04e-65 219.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_21858_1 322855.Q52PN7_9CAUD 6.46e-22 99.4 4QBNE@10239|Viruses,4QXM4@35237|dsDNA viruses no RNA stage,4QPE9@28883|Caudovirales 28883|Caudovirales S Pfam:Carbam_trans_C - - - - - - - - - - - - - k59_31819_1 1121422.AUMW01000021_gene1621 0.000139 48.9 COG3108@1|root,COG3409@1|root,COG3108@2|Bacteria,COG3409@2|Bacteria 2|Bacteria M Peptidoglycan-binding domain 1 protein - - 3.4.17.14 ko:K08640 - - - - ko00000,ko01000,ko01002,ko01011 - - - PG_binding_1,Peptidase_M15_3,Transglycosylas k59_237421_1 1325130.HFN_0354 2.85e-12 67.4 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,42RN6@68525|delta/epsilon subdivisions,2YP9W@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_237421_2 1070319.CAGGBEG34_190022 6.52e-20 92.0 COG3723@1|root,COG3723@2|Bacteria,1R6DB@1224|Proteobacteria,2VNV4@28216|Betaproteobacteria,1K7AD@119060|Burkholderiaceae 28216|Betaproteobacteria L PFAM RecT protein recT - - ko:K07455 - - - - ko00000,ko03400 - - - RecT k59_205689_1 314607.KB13_1178 1.27e-52 185.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,2VIKN@28216|Betaproteobacteria,1KPR6@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_196271_1 1788452.A0A190WHG0_9CIRC 9.53e-47 164.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_7383_1 1417599.U6C7Z1_9CAUD 5.8e-23 99.8 4QD9Y@10239|Viruses,4QUXQ@35237|dsDNA viruses no RNA stage,4QTPE@28883|Caudovirales,4QNY4@10744|Podoviridae 10744|Podoviridae S Terminase-like family - - - - - - - - - - - - - k59_96725_1 745310.G432_10085 1.17e-24 100.0 COG3751@1|root,COG3751@2|Bacteria,1RJST@1224|Proteobacteria,2UAC0@28211|Alphaproteobacteria,2K387@204457|Sphingomonadales 204457|Sphingomonadales O 2OG-Fe(II) oxygenase superfamily - - - - - - - - - - - - 2OG-FeII_Oxy_3 k59_96725_2 1227500.C494_05593 3.52e-08 55.8 arCOG01782@1|root,arCOG01782@2157|Archaea,2XTX4@28890|Euryarchaeota,23TWF@183963|Halobacteria 183963|Halobacteria Q COG0500 SAM-dependent methyltransferases - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 k59_115827_3 207559.Dde_2894 2.27e-07 58.2 COG2242@1|root,COG2242@2|Bacteria,1MYGE@1224|Proteobacteria,42VGU@68525|delta/epsilon subdivisions,2WS5G@28221|Deltaproteobacteria,2M91U@213115|Desulfovibrionales 28221|Deltaproteobacteria H TIGRFAM methyltransferase FkbM - - - - - - - - - - - - Methyltransf_21 k59_206570_2 1123008.KB905697_gene3236 3.95e-05 55.1 COG3210@1|root,COG3210@2|Bacteria,4PPCP@976|Bacteroidetes 976|Bacteroidetes U Chaperone of endosialidase - - - - - - - - - - - - Peptidase_S74 k59_190414_2 319225.Plut_0075 4.36e-09 60.8 COG0216@1|root,COG0216@2|Bacteria,1FDJD@1090|Chlorobi 1090|Chlorobi J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA - - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 k59_197234_1 981335.G4W934_9CAUD 8.77e-63 202.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales 28883|Caudovirales S N-methyltransferase activity - - - - - - - - - - - - - k59_132074_5 234831.PSM_A0149 1.76e-29 122.0 COG1226@1|root,COG1226@2|Bacteria,1NT9G@1224|Proteobacteria,1RZME@1236|Gammaproteobacteria,2Q04W@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria P COG1226 Kef-type K transport systems VP1064 - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans_2,TrkA_N k59_197388_1 105154.Q9MBU6_9VIRU 2.05e-56 194.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_213652_1 322855.Q52PS3_9CAUD 7.53e-36 135.0 4QAUS@10239|Viruses,4QURX@35237|dsDNA viruses no RNA stage,4QQ2S@28883|Caudovirales 28883|Caudovirales S flavin adenine dinucleotide binding - - - - - - - - - - - - - k59_115944_2 1862825.A0A193CDY3_9VIRU 1.44e-58 190.0 4QB6C@10239|Viruses 10239|Viruses L Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_206684_1 1122621.ATZA01000071_gene2343 1.3e-19 85.5 COG2131@1|root,COG2131@2|Bacteria,4NM48@976|Bacteroidetes,1IRSP@117747|Sphingobacteriia 976|Bacteroidetes F PFAM Cytidine and deoxycytidylate deaminase zinc-binding region comEB - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 k59_57350_1 1004785.AMBLS11_12290 2.79e-10 72.8 COG3209@1|root,COG4733@1|root,COG3209@2|Bacteria,COG4733@2|Bacteria,1R7KR@1224|Proteobacteria,1S1E5@1236|Gammaproteobacteria 1236|Gammaproteobacteria D COG4733 Phage-related protein, tail component - - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - DUF1983,Phage-tail_3 k59_57350_13 596153.Alide_1253 5.84e-10 59.3 28SSJ@1|root,2ZF2C@2|Bacteria,1RBGE@1224|Proteobacteria,2VTTC@28216|Betaproteobacteria 28216|Betaproteobacteria S Protein of unknown function (DUF2442) - - - - - - - - - - - - DUF2442 k59_57350_19 1124991.MU9_2764 1.61e-46 179.0 COG1061@1|root,COG1061@2|Bacteria,1MV9F@1224|Proteobacteria,1RNAN@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Type III restriction protein res subunit yejH GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042221,GO:0042493,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051301,GO:0051716,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - ko:K19789 - - - - ko00000,ko03400 - - - Helicase_C,ResIII k59_107806_1 322855.Q52PN4_9CAUD 5.32e-30 128.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales 28883|Caudovirales S N-methyltransferase activity - - - - - - - - - - - - - k59_248597_1 272123.Anacy_0525 7.87e-41 150.0 COG0438@1|root,COG0438@2|Bacteria,1GC4D@1117|Cyanobacteria 1117|Cyanobacteria M PFAM Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_4 k59_265129_1 1692244.A0A0K1RLR5_9CIRC 2.9e-92 279.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_99335_1 1692250.A0A0K1RLR1_9CIRC 1.64e-31 117.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_265132_1 1634476.A0A0F6TGK2_9CIRC 4.88e-30 121.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_248616_1 391595.RLO149_c014800 2.8e-22 92.4 2EJIR@1|root,33D9N@2|Bacteria,1NHKK@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - DUF4376,Phage_tail_APC k59_66246_1 996306.SSUR61_0556 2.28e-54 184.0 COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,4HBD5@91061|Bacilli,1WSZP@1307|Streptococcus suis 91061|Bacilli T PhoH-like protein phoH - - ko:K06217 - - - - ko00000 - - - PhoH k59_265133_1 1005995.GTPT_3397 3.37e-64 211.0 COG5655@1|root,COG5655@2|Bacteria,1N22J@1224|Proteobacteria,1SRUQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria L COG5655 Plasmid rolling circle replication initiator protein and truncated derivatives - - - - - - - - - - - - Rep_1 k59_99357_1 1357732.A0A059PYE1_9CAUD 1.04e-61 228.0 4QBWF@10239|Viruses,4QZPF@35237|dsDNA viruses no RNA stage,4QRA3@28883|Caudovirales,4QNG4@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_66418_2 314262.MED193_18924 1.95e-20 101.0 2EPTJ@1|root,33HE3@2|Bacteria,1NNYK@1224|Proteobacteria,2UWK5@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_132781_2 428125.CLOLEP_01411 2.64e-111 341.0 28J3N@1|root,2Z8ZU@2|Bacteria,1V15Z@1239|Firmicutes,249Z0@186801|Clostridia,3WNJZ@541000|Ruminococcaceae 186801|Clostridia S Phage portal protein - - - - - - - - - - - - Phage_portal k59_232971_22 1131315.H2DE37_9CAUD 6.16e-247 712.0 4QCM6@10239|Viruses,4QVAQ@35237|dsDNA viruses no RNA stage,4QPVV@28883|Caudovirales,4QNID@10744|Podoviridae 10744|Podoviridae S actin binding - - - - - - - - - - - - - k59_232971_26 644524.C5IHN6_9CAUD 2.37e-248 697.0 4QF06@10239|Viruses,4QVMB@35237|dsDNA viruses no RNA stage,4QPRV@28883|Caudovirales,4QP2V@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_232971_27 935557.ATYB01000014_gene1481 7.78e-53 172.0 2BVDA@1|root,32QTA@2|Bacteria,1MYBS@1224|Proteobacteria,2UZ7N@28211|Alphaproteobacteria,4BF99@82115|Rhizobiaceae 28211|Alphaproteobacteria S DNA-packaging protein gp3 - - - - - - - - - - - - GP3_package k59_232971_32 1338011.BD94_0591 1.17e-06 51.6 COG2003@1|root,COG2003@2|Bacteria,4PPJN@976|Bacteroidetes,1IKW0@117743|Flavobacteriia 976|Bacteroidetes L RadC-like JAB domain - - - - - - - - - - - - RadC k59_232971_39 211586.SO_3001 2.99e-39 137.0 28UB5@1|root,2ZGGM@2|Bacteria,1P5II@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_232971_41 1191380.J7I0S8_9CAUD 1.37e-51 170.0 4QD4R@10239|Viruses,4QUPD@35237|dsDNA viruses no RNA stage,4QTAJ@28883|Caudovirales 28883|Caudovirales S Protein of unknown function (DUF3268) - - - - - - - - - - - - - k59_100351_1 1410609.JHVB01000002_gene1373 1.08e-29 127.0 COG0749@1|root,COG0749@2|Bacteria,2J5FM@203691|Spirochaetes 203691|Spirochaetes L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_50727_4 195253.Syn6312_0710 1.57e-15 84.0 COG1215@1|root,COG1215@2|Bacteria,1G12A@1117|Cyanobacteria,1H432@1129|Synechococcus 1117|Cyanobacteria M COG0463 Glycosyltransferases involved in cell wall biogenesis - - - - - - - - - - - - Glycos_transf_2 k59_108731_1 105154.Q9MBU6_9VIRU 2.95e-36 135.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_108731_3 1165094.RINTHH_3920 8.06e-77 245.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_108731_8 1385658.U5KPZ6_9VIRU 1.65e-180 522.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_241388_1 411902.CLOBOL_04837 1.2e-05 47.8 COG0791@1|root,COG3772@1|root,COG0791@2|Bacteria,COG3772@2|Bacteria,1VG3D@1239|Firmicutes,25FTG@186801|Clostridia,223QR@1506553|Lachnoclostridium 186801|Clostridia M Phage lysozyme - - - - - - - - - - - - - k59_34246_1 397278.JOJN01000007_gene3288 4.42e-07 53.5 COG2909@1|root,COG2909@2|Bacteria,2GM1B@201174|Actinobacteria,4DTFJ@85009|Propionibacteriales 201174|Actinobacteria K AAA ATPase domain - - - - - - - - - - - - AAA_16,BTAD,GerE,Trans_reg_C k59_42448_1 97138.C820_01005 3.09e-05 52.4 COG1783@1|root,COG1783@2|Bacteria,1TRQP@1239|Firmicutes,248E9@186801|Clostridia,36EE3@31979|Clostridiaceae 186801|Clostridia L Phage terminase, large subunit, PBSX family - - - ko:K06909 - - - - ko00000 - - - Terminase_2,Terminase_3,Terminase_3C k59_1124_1 1234888.K0A2J2_9VIRU 4.16e-45 165.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_1124_3 115711.CP_0543 4.6e-22 95.5 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_83771_3 1234888.K0A2J2_9VIRU 2.64e-121 371.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_83771_5 1234888.K0A2R8_9VIRU 3.56e-46 163.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_2317_2 1121459.AQXE01000001_gene2748 2.1e-33 122.0 2AGTB@1|root,3171D@2|Bacteria,1RJGM@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - DUF2833 k59_159232_1 1028800.RG540_CH13740 3.33e-47 171.0 COG0749@1|root,COG0749@2|Bacteria,1P27P@1224|Proteobacteria,2TVEI@28211|Alphaproteobacteria,4BIH2@82115|Rhizobiaceae 28211|Alphaproteobacteria L DNA polymerase A domain - - - - - - - - - - - - DNA_pol_A k59_168032_1 1380387.JADM01000008_gene954 6.97e-06 48.9 COG1403@1|root,COG1403@2|Bacteria,1RIBS@1224|Proteobacteria,1S88N@1236|Gammaproteobacteria 1236|Gammaproteobacteria V Bacteriophage Lambda NinG protein - - - - - - - - - - - - NinG k59_76721_2 1234888.K0A2J2_9VIRU 2.08e-51 180.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_126680_3 742727.HMPREF9447_00582 4.92e-135 393.0 COG0175@1|root,COG0175@2|Bacteria,4PAD4@976|Bacteroidetes,2FWM0@200643|Bacteroidia 976|Bacteroidetes EH Phosphoadenosine phosphosulfate reductase family - - - - - - - - - - - - PAPS_reduct k59_18107_1 428127.EUBDOL_01565 7.25e-10 70.9 COG4733@1|root,COG4926@1|root,COG4733@2|Bacteria,COG4926@2|Bacteria,1TTBV@1239|Firmicutes,3VQVG@526524|Erysipelotrichia 526524|Erysipelotrichia S cellulase activity - - - - - - - - - - - - - k59_118509_1 1986029.Q9MBM3_9VIRU 1.32e-32 126.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_175877_1 1174528.JH992892_gene6255 1.68e-55 196.0 2C085@1|root,33VBW@2|Bacteria,1G7KS@1117|Cyanobacteria 1117|Cyanobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6C k59_18108_1 460265.Mnod_6992 1.94e-22 95.9 COG0270@1|root,COG0270@2|Bacteria,1MV9H@1224|Proteobacteria,2TTZG@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family dcm - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase,HTH_3,HTH_31 k59_18108_2 1335230.S5VMD2_9CAUD 2.3e-48 166.0 4QG35@10239|Viruses,4QUX3@35237|dsDNA viruses no RNA stage,4QUFA@28883|Caudovirales,4QJIT@10662|Myoviridae 10662|Myoviridae S tRNA wobble uridine modification - - - - - - - - - - - - - k59_159233_4 1219035.NT2_13_00580 1.6e-81 264.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_233827_2 1090134.G5DEG8_9CAUD 2.29e-16 79.7 4QBHE@10239|Viruses,4R09B@35237|dsDNA viruses no RNA stage,4QPAG@28883|Caudovirales,4QJZ5@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_35223_2 1385658.U5KPZ6_9VIRU 6.67e-25 106.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_234631_3 1082931.KKY_773 1.26e-11 67.8 28JTG@1|root,2Z7PY@2|Bacteria,1QVNY@1224|Proteobacteria,2TXVN@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF2793) - - - - - - - - - - - - DUF2793 k59_28351_1 1609634.A0A0C5AFT2_9VIRU 4.69e-31 123.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_152715_2 596152.DesU5LDRAFT_3296 1.78e-24 104.0 COG0305@1|root,COG0305@2|Bacteria,1PZ6S@1224|Proteobacteria,42YZ3@68525|delta/epsilon subdivisions,2WU0W@28221|Deltaproteobacteria,2MAW9@213115|Desulfovibrionales 28221|Deltaproteobacteria L Toprim-like - - - - - - - - - - - - DnaB_C,Toprim_2 k59_19100_1 323097.Nham_3219 1.51e-23 101.0 COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,2TT4Q@28211|Alphaproteobacteria,3JU3F@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L UreE urease accessory protein, C-terminal domain udgA - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k59_19100_2 1231190.NA8A_19588 8.05e-14 69.3 COG0863@1|root,COG0863@2|Bacteria,1R7KV@1224|Proteobacteria,2U3KV@28211|Alphaproteobacteria,43Q9K@69277|Phyllobacteriaceae 28211|Alphaproteobacteria L DNA methylase - - 2.1.1.72 ko:K00571,ko:K07319 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_102532_1 1337936.IJ00_12195 1.41e-32 130.0 COG0582@1|root,COG0582@2|Bacteria,1G0M1@1117|Cyanobacteria,1HKZK@1161|Nostocales 1117|Cyanobacteria L phage integrase family - - - - - - - - - - - - Phage_integrase k59_102532_2 1231185.BAMP01000018_gene3071 3.4e-12 71.6 COG5448@1|root,COG5448@2|Bacteria,1MXM8@1224|Proteobacteria,2TTJ3@28211|Alphaproteobacteria,43H4Y@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Conserved hypothetical protein 2217 (DUF2460) - - - - - - - - - - - - DUF2460 k59_69326_1 1385658.U5KPZ6_9VIRU 5.24e-106 330.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_193221_1 1609634.A0A0C5AFV4_9VIRU 1.79e-40 155.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_251306_1 1003195.SCAT_1653 3.15e-09 57.0 2EI4V@1|root,33BW7@2|Bacteria,2I5MI@201174|Actinobacteria 201174|Actinobacteria S Protein of unknwon function (DUF3310) - - - - - - - - - - - - DUF3310 k59_234701_1 691965.D4P7I3_9CAUD 1.68e-284 825.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_234701_5 478749.BRYFOR_08565 7.75e-44 158.0 2A0KC@1|root,2ZGJK@2|Bacteria,1V2JS@1239|Firmicutes,24H6R@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_44713_1 445686.E3SL58_9CAUD 3.44e-91 287.0 4QES4@10239|Viruses,4QXT9@35237|dsDNA viruses no RNA stage,4QQEY@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_152875_1 696281.Desru_1084 1.19e-07 56.2 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia 186801|Clostridia L snf2 family - - - - - - - - - - - - SNF2_N k59_111252_1 375286.mma_2206 7.2e-108 329.0 COG5323@1|root,COG5323@2|Bacteria 2|Bacteria M Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6 k59_94049_5 1209072.ALBT01000003_gene703 1.02e-73 238.0 COG0582@1|root,COG0582@2|Bacteria,1QWI5@1224|Proteobacteria,1T2VS@1236|Gammaproteobacteria 1236|Gammaproteobacteria L viral genome integration into host DNA - - - - - - - - - - - - - k59_94049_6 520709.F985_01890 3.71e-98 297.0 COG0270@1|root,COG0270@2|Bacteria,1N0XD@1224|Proteobacteria,1T05A@1236|Gammaproteobacteria 1236|Gammaproteobacteria L C-5 cytosine-specific DNA methylase - - - - - - - - - - - - DNA_methylase k59_28512_2 1556290.A0A0A0RKR9_9CAUD 8.58e-07 54.7 4QG66@10239|Viruses,4QUJP@28883|Caudovirales,4QMHX@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_234704_1 243233.MCA1515 6.23e-34 132.0 COG0438@1|root,COG4627@1|root,COG0438@2|Bacteria,COG4627@2|Bacteria,1N2HA@1224|Proteobacteria,1SJB1@1236|Gammaproteobacteria 1236|Gammaproteobacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Methyltransf_11 k59_60774_2 716928.AJQT01000109_gene1217 2.32e-32 117.0 2FEUE@1|root,346TC@2|Bacteria,1MZPB@1224|Proteobacteria,2UC4Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_94052_1 1234881.K0A1K7_9CIRC 2.85e-05 51.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_112761_1 563192.HMPREF0179_02930 2.66e-09 55.8 2EI4V@1|root,33BW7@2|Bacteria,1NN3Z@1224|Proteobacteria,432C4@68525|delta/epsilon subdivisions,2WXM5@28221|Deltaproteobacteria,2MFUS@213115|Desulfovibrionales 1224|Proteobacteria S Protein of unknwon function (DUF3310) - - - - - - - - - - - - DUF3310 k59_112761_4 445693.E3SN95_9CAUD 1.46e-16 79.0 4QASP@10239|Viruses,4QVR8@35237|dsDNA viruses no RNA stage,4QR4Z@28883|Caudovirales,4QNQ0@10744|Podoviridae 10744|Podoviridae S deoxyribonuclease IV (phage-T4-induced) activity - - - - - - - - - - - - - k59_235800_1 1506716.A0A076G4Y4_9CAUD 4.59e-05 50.8 4QB5I@10239|Viruses 10239|Viruses S N-methyltransferase activity - - - - - - - - - - - - - k59_129655_1 1441930.Z042_23145 8.03e-37 130.0 2D1MV@1|root,32TAZ@2|Bacteria,1N45A@1224|Proteobacteria,1S954@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage protein (N4 Gp49/phage Sf6 gene 66) family - - - - - - - - - - - - DUF2829,Phage_gp49_66 k59_129655_2 1081640.AGFU01000078_gene3370 1.55e-09 56.2 COG3772@1|root,COG3772@2|Bacteria,1N0ZQ@1224|Proteobacteria,2UFT6@28211|Alphaproteobacteria,2KAF3@204457|Sphingomonadales 204457|Sphingomonadales S Phage lysozyme - - - - - - - - - - - - Phage_lysozyme k59_228527_1 1279017.AQYJ01000016_gene407 7.09e-32 131.0 COG4733@1|root,COG4733@2|Bacteria,1R77Q@1224|Proteobacteria 1224|Proteobacteria D nuclear chromosome segregation - - - - - - - - - - - - - k59_79007_2 864073.HFRIS_014864 8.72e-79 241.0 COG4725@1|root,COG4725@2|Bacteria,1R553@1224|Proteobacteria,2VMV0@28216|Betaproteobacteria 28216|Betaproteobacteria KT Belongs to the MT-A70-like family - - - - - - - - - - - - MT-A70 k59_178582_1 1545915.JROG01000004_gene1901 2.01e-06 53.5 2DSHN@1|root,33G5Q@2|Bacteria,1NGM3@1224|Proteobacteria,2UK0H@28211|Alphaproteobacteria,2K4KJ@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - k59_103758_1 89187.ISM_08070 1.05e-45 156.0 28PMA@1|root,2ZCAD@2|Bacteria,1RARQ@1224|Proteobacteria,2U6X3@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_103758_2 1408418.JNJH01000015_gene3301 4.06e-22 99.0 COG0863@1|root,COG0863@2|Bacteria,1R7RR@1224|Proteobacteria,2TS8Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - - - - - - - - - - - N6_N4_Mtase k59_235813_2 742740.HMPREF9474_02272 9.83e-87 273.0 COG4626@1|root,COG4626@2|Bacteria,1TT9I@1239|Firmicutes,24AFK@186801|Clostridia,222GA@1506553|Lachnoclostridium 186801|Clostridia S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_70755_1 437329.A5A3S0_9CAUD 3.07e-36 135.0 4QFED@10239|Viruses,4R072@35237|dsDNA viruses no RNA stage,4QPEH@28883|Caudovirales,4QN2V@10699|Siphoviridae 10699|Siphoviridae S tRNA modification - - - - - - - - - - - - - k59_129671_1 1385658.U5KPZ6_9VIRU 1.4e-51 180.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_261730_3 1144319.PMI16_01375 3.31e-09 60.8 COG4970@1|root,COG4970@2|Bacteria,1NGHS@1224|Proteobacteria,2WCQV@28216|Betaproteobacteria,474MH@75682|Oxalobacteraceae 28216|Betaproteobacteria NU Type II transport protein GspH fimT - - ko:K08084 - - - - ko00000,ko02044 3.A.15.2 - - GspH,N_methyl k59_79798_1 1379713.S5SYD9_9CIRC 4.8e-17 79.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_13195_1 1121396.KB893057_gene2480 4.66e-08 59.3 2DB7C@1|root,2Z7KN@2|Bacteria,1N20J@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_104715_1 1120963.KB894501_gene316 1.66e-28 108.0 COG2852@1|root,COG2852@2|Bacteria,1N7EJ@1224|Proteobacteria,1SF5D@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - DUF559 k59_6306_1 940282.CADQ01000042_gene690 4.9e-16 84.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2TSDW@28211|Alphaproteobacteria,2JYGZ@204441|Rhodospirillales 204441|Rhodospirillales S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_30835_1 1634488.A0A0E3JHI1_9VIRU 7.7e-08 55.8 4QB6C@10239|Viruses 10239|Viruses L Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_104858_2 1618251.A0A0C5I2L8_9CIRC 6.49e-80 251.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_47644_4 700939.E5FIH0_9CAUD 6.44e-07 52.8 4QCN3@10239|Viruses,4R03K@35237|dsDNA viruses no RNA stage,4QR5D@28883|Caudovirales,4QI2B@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_236754_3 1986029.Q9MBM6_9VIRU 2.3e-11 65.1 4QDBB@10239|Viruses,4QUM0@29258|ssDNA viruses,4QP4D@10841|Microviridae 10841|Microviridae S Chlamydia-phage Chp2 scaffold (Chlamy_scaf) - - - - - - - - - - - - - k59_212039_4 1234888.K0A2J2_9VIRU 2.26e-83 265.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_6463_1 1123072.AUDH01000023_gene751 4.34e-06 52.8 COG3378@1|root,COG3598@1|root,COG3378@2|Bacteria,COG3598@2|Bacteria,1MV7I@1224|Proteobacteria,2TRS2@28211|Alphaproteobacteria,2JW3C@204441|Rhodospirillales 204441|Rhodospirillales L D5 N terminal like - - - - - - - - - - - - D5_N k59_71997_1 105154.Q9MBU3_9VIRU 5.21e-09 61.6 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_204861_1 1147140.H6WRY9_9CAUD 5.28e-31 120.0 4QEMB@10239|Viruses,4QVSG@35237|dsDNA viruses no RNA stage,4QQ55@28883|Caudovirales,4QNA8@10699|Siphoviridae 10699|Siphoviridae S Bacteriophage Lambda NinG protein - - - - - - - - - - - - - k59_195608_1 758.BBIX01000008_gene931 8.23e-56 187.0 2CI0W@1|root,2Z81W@2|Bacteria,1R9FZ@1224|Proteobacteria,1S0NA@1236|Gammaproteobacteria,1Y9SV@135625|Pasteurellales 1236|Gammaproteobacteria S Phage X family - - - - - - - - - - - - Phage_CRI,Phage_X k59_171919_1 587753.EY04_17215 2.09e-117 351.0 COG2369@1|root,COG2369@2|Bacteria,1PUNX@1224|Proteobacteria,1S0QA@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Head morphogenesis protein - - - - - - - - - - - - Phage_Mu_F k59_171919_2 220664.PFL_3762 7.58e-16 76.6 2BHS1@1|root,32BVJ@2|Bacteria,1RIYT@1224|Proteobacteria,1S7CG@1236|Gammaproteobacteria,1YS75@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_32545_1 1157634.KB912959_gene1714 3.78e-43 150.0 2C5J1@1|root,3067M@2|Bacteria,2IKFX@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_32545_2 420662.Mpe_A2998 2.21e-38 142.0 COG0582@1|root,COG0582@2|Bacteria,1MWBN@1224|Proteobacteria,2VW9J@28216|Betaproteobacteria 28216|Betaproteobacteria L Phage integrase family - - - - - - - - - - - - Phage_integrase k59_196825_1 1121468.AUBR01000008_gene2081 0.000879 43.5 COG4570@1|root,COG4570@2|Bacteria,1UDK7@1239|Firmicutes,24T1T@186801|Clostridia,42INU@68295|Thermoanaerobacterales 186801|Clostridia L PFAM endodeoxyribonuclease RusA - - 3.1.22.4 ko:K01160 - - - - ko00000,ko01000,ko03400 - - - RusA k59_196825_2 634452.APA01_26890 3.91e-13 78.6 COG3598@1|root,COG3598@2|Bacteria,1N7TV@1224|Proteobacteria,2U53X@28211|Alphaproteobacteria,2JXGJ@204441|Rhodospirillales 204441|Rhodospirillales L Bifunctional DNA primase/polymerase, N-terminal - - - - - - - - - - - - Prim-Pol k59_237944_1 1226994.AMZB01000137_gene5405 2.51e-52 188.0 COG3064@1|root,COG3064@2|Bacteria,1R6JV@1224|Proteobacteria 1224|Proteobacteria M Membrane - - - - - - - - - - - - - k59_140204_3 1003200.AXXA_27990 1.81e-37 137.0 28HXV@1|root,2Z83C@2|Bacteria,1PJBP@1224|Proteobacteria,2W8RH@28216|Betaproteobacteria,3T5DR@506|Alcaligenaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_206290_2 1211814.CAPG01000027_gene1326 6.24e-13 71.2 COG5301@1|root,COG5301@2|Bacteria,1VEZ9@1239|Firmicutes,4HNUH@91061|Bacilli 91061|Bacilli G cellulose 1,4-beta-cellobiosidase activity - - - - - - - - - - - - - k59_63833_1 521674.Plim_2641 0.000155 46.2 2E3Q3@1|root,32YN2@2|Bacteria,2J0W4@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - k59_264159_1 1166948.JPZL01000002_gene1836 1.86e-21 87.4 2EMXC@1|root,33FJM@2|Bacteria,1NFNP@1224|Proteobacteria,1SIUQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_63834_1 156889.Mmc1_1690 5.95e-51 178.0 COG1783@1|root,COG1783@2|Bacteria,1MVJB@1224|Proteobacteria,2U2BM@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6 k59_190103_1 673839.D2J048_9CAUD 1.7e-71 241.0 4QCHV@10239|Viruses,4QUW9@35237|dsDNA viruses no RNA stage,4QQEZ@28883|Caudovirales,4QMEA@10699|Siphoviridae 10699|Siphoviridae S Virulence-associated protein E - - - - - - - - - - - - - k59_264163_2 675812.VHA_000295 1.16e-20 89.0 2DMPB@1|root,32SV8@2|Bacteria,1NHUE@1224|Proteobacteria,1SIKI@1236|Gammaproteobacteria,1XY3E@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k59_115585_3 716928.AJQT01000109_gene1216 1.44e-07 58.2 2A70H@1|root,30VVP@2|Bacteria,1NFHJ@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_149002_1 292414.TM1040_0821 9.46e-08 59.3 COG3391@1|root,COG3391@2|Bacteria 2|Bacteria CO amine dehydrogenase activity - - - ko:K12287 - - - - ko00000,ko02044 - - - DUF11,VCBS k59_149107_1 1300350.DSW25_02400 1.98e-31 123.0 COG3935@1|root,COG3935@2|Bacteria,1MXB6@1224|Proteobacteria,2U3BK@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DnaD domain protein - - - - - - - - - - - - - k59_215180_2 145579.C_BPPHM 5.64e-09 55.5 4QCC5@10239|Viruses,4QUKW@29258|ssDNA viruses,4QP4C@10841|Microviridae 10841|Microviridae S viral process - - - - - - - - - - - - - k59_215180_3 1609634.A0A0C5AFV4_9VIRU 2.46e-05 46.2 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_256856_1 1609634.A0A0C5AFV4_9VIRU 8.07e-60 201.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_65730_2 313628.LNTAR_21400 1.78e-18 92.4 COG3291@1|root,COG4447@1|root,COG3291@2|Bacteria,COG4447@2|Bacteria 2|Bacteria S cellulose binding - - 3.2.1.4,3.2.1.73 ko:K01179,ko:K01216,ko:K21449 ko00500,ko01100,map00500,map01100 - R06200,R11307,R11308 - ko00000,ko00001,ko01000,ko02000 1.B.40.2 GH5,GH9 - CBM_3,F5_F8_type_C,PKD,fn3 k59_98870_1 1461577.CCMH01000006_gene1986 1.44e-11 73.9 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,1HXMT@117743|Flavobacteriia 976|Bacteroidetes L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_16468_1 1556290.A0A0A0RQP8_9CAUD 1.14e-55 199.0 4QBG4@10239|Viruses,4QRSK@28883|Caudovirales,4QKVU@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_99122_5 691965.D4P7C5_9CAUD 2.8e-59 199.0 4QBV3@10239|Viruses,4QW0W@35237|dsDNA viruses no RNA stage,4QPPJ@28883|Caudovirales,4QKW5@10699|Siphoviridae 10699|Siphoviridae S Phage Terminase - - - - - - - - - - - - - k59_240304_2 136084.Q9G0F7_9CAUD 8.41e-23 105.0 4QH2I@10239|Viruses,4QWWD@35237|dsDNA viruses no RNA stage,4QQE9@28883|Caudovirales,4QNFX@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_265090_2 1692258.A0A0K1RL51_9CIRC 5e-57 192.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_248414_4 1229172.JQFA01000002_gene4632 2.06e-16 82.0 COG3772@1|root,COG3772@2|Bacteria,1G7YF@1117|Cyanobacteria,1HASB@1150|Oscillatoriales 1117|Cyanobacteria M Phage lysozyme - - - - - - - - - - - - PG_binding_1,Phage_lysozyme k59_99130_1 1524880.A0A076G5J7_9VIRU 2.42e-13 75.1 4QE8X@10239|Viruses 10239|Viruses S Phage phiEco32-like COOH.NH2 ligase-type 2 - - - - - - - - - - - - - k59_107630_1 1609634.A0A0C5AFV4_9VIRU 5.03e-91 286.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_89982_1 1458858.A0A088C4G9_9CAUD 8.4e-29 113.0 4QBK0@10239|Viruses,4QUSV@35237|dsDNA viruses no RNA stage,4QU9J@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_99146_2 1618248.A0A0C5IB82_9CIRC 1.53e-85 266.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_265095_1 1692257.A0A0K1RL39_9CIRC 7.92e-70 224.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_66067_1 1121129.KB903359_gene1822 8.03e-10 60.5 COG0847@1|root,COG0847@2|Bacteria,4NP7B@976|Bacteroidetes,2FSMF@200643|Bacteroidia,22Y26@171551|Porphyromonadaceae 976|Bacteroidetes L Exonuclease - - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T k59_240341_1 626887.J057_01785 6.03e-23 102.0 2DCM2@1|root,32TZV@2|Bacteria,1NAGE@1224|Proteobacteria,1SMRS@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_199703_21 2754.EH55_13305 8.58e-16 78.6 COG3926@1|root,COG3926@2|Bacteria,3TBJA@508458|Synergistetes 508458|Synergistetes S Predicted Peptidoglycan domain - - - - - - - - - - - - Glyco_hydro_108,PG_binding_3 k59_199703_22 1444712.BN1013_01280 1.07e-228 654.0 COG0209@1|root,COG0209@2|Bacteria,2JFJ7@204428|Chlamydiae 204428|Chlamydiae F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides rtpR - 1.1.98.6 ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000 - - - - k59_174595_2 261292.Nit79A3_1409 3.83e-22 93.2 COG0863@1|root,COG0863@2|Bacteria 2|Bacteria L N-4 methylation of cytosine - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_207923_3 1347392.CCEZ01000011_gene2447 3.26e-45 160.0 COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,36DTR@31979|Clostridiaceae 186801|Clostridia L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_9043_3 948071.S4S2D9_9CAUD 2.19e-206 593.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QNQ6@10744|Podoviridae 10744|Podoviridae S ribonucleoside-triphosphate reductase activity - - - - - - - - - - - - - k59_224643_9 1357714.A0A067XRB3_9CAUD 4.67e-13 69.7 4QCXM@10239|Viruses,4QZZ5@35237|dsDNA viruses no RNA stage,4QT8U@28883|Caudovirales,4QJ27@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_67122_3 187764.Q8SCG8_9CAUD 1.75e-35 147.0 4QBMV@10239|Viruses,4QUU6@35237|dsDNA viruses no RNA stage,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_25742_1 1150626.PHAMO_80072 7.32e-35 134.0 COG1783@1|root,COG1783@2|Bacteria,1R66A@1224|Proteobacteria,2TV42@28211|Alphaproteobacteria,2JXEM@204441|Rhodospirillales 204441|Rhodospirillales S Terminase-like family - - - - - - - - - - - - - k59_224645_2 1618260.A0A0C5I2C5_9CIRC 3.92e-24 102.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_75403_2 1379719.S5TMX6_9CIRC 1.09e-33 130.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_100223_1 1219035.NT2_13_00580 1.02e-22 100.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_58720_1 1399774.JDWH01000016_gene3456 2.54e-10 60.5 2CWYZ@1|root,32T0P@2|Bacteria,1MZEM@1224|Proteobacteria,1S9HP@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_92006_1 1692248.A0A0K1RLN2_9CIRC 6.82e-42 148.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_34014_2 1692252.A0A0K1RL35_9CIRC 6.51e-95 289.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_42222_1 1219031.BBJR01000049_gene1548 1.74e-14 71.6 COG3756@1|root,COG3756@2|Bacteria,1QUEM@1224|Proteobacteria,2WHQP@28216|Betaproteobacteria,4AIKF@80864|Comamonadaceae 28216|Betaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - - k59_25837_1 1692258.A0A0K1RL51_9CIRC 2.61e-69 221.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_151141_1 483216.BACEGG_02723 1.45e-07 55.8 2BP9Z@1|root,32I1T@2|Bacteria,4PE07@976|Bacteroidetes,2FW3U@200643|Bacteroidia,4AUA1@815|Bacteroidaceae 976|Bacteroidetes - - - - - - - - - - - - - - - k59_43321_1 412597.AEPN01000059_gene3564 8.11e-39 150.0 COG3505@1|root,COG3505@2|Bacteria 412597.AEPN01000059_gene3564|- U unidirectional conjugation - - - - - - - - - - - - - k59_84427_1 1692259.A0A0K1RL59_9CIRC 1.91e-20 98.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_184018_2 1234888.K0A2J2_9VIRU 1.94e-107 335.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_109447_1 178901.AmDm5_0228 1.42e-15 76.3 COG1351@1|root,COG1351@2|Bacteria,1MWY8@1224|Proteobacteria,2TTER@28211|Alphaproteobacteria,2JQGP@204441|Rhodospirillales 204441|Rhodospirillales F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant thyX - 2.1.1.148 ko:K03465 ko00240,ko00670,ko01100,map00240,map00670,map01100 - R06613 RC00022,RC00332 ko00000,ko00001,ko01000 - - - Thy1 k59_109447_2 511.JT27_18245 4.88e-101 314.0 COG1475@1|root,COG1475@2|Bacteria,1QU9G@1224|Proteobacteria 1224|Proteobacteria K ParB-like nuclease domain - - - - - - - - - - - - ParBc k59_118254_1 608538.HTH_0614 1.86e-24 108.0 COG0305@1|root,COG0305@2|Bacteria,2G3QP@200783|Aquificae 200783|Aquificae L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_51665_1 1609634.A0A0C5AFT2_9VIRU 4.03e-22 100.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_225889_1 1504822.CCNO01000015_gene594 7.38e-56 194.0 COG0553@1|root,COG0863@1|root,COG0553@2|Bacteria,COG0863@2|Bacteria 2|Bacteria L N-4 methylation of cytosine - - - - - - - - - - - - Helicase_C,N6_N4_Mtase,SNF2_N k59_175721_1 438753.AZC_3575 1.94e-86 271.0 COG5410@1|root,COG5410@2|Bacteria,1N0W2@1224|Proteobacteria,2U18J@28211|Alphaproteobacteria 28211|Alphaproteobacteria K chromosome segregation - - - - - - - - - - - - Terminase_6C k59_175721_4 1401297.U3PIR1_9CAUD 4.8e-06 47.8 4QG7B@10239|Viruses,4QV9D@35237|dsDNA viruses no RNA stage,4QT29@28883|Caudovirales,4QNM0@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_175721_7 477184.KYC_12803 1.83e-23 97.1 29XIZ@1|root,30J9Y@2|Bacteria,1NNKQ@1224|Proteobacteria,2WHUE@28216|Betaproteobacteria,3T8BH@506|Alcaligenaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_175721_8 243265.plu3502 2.61e-16 75.5 COG5301@1|root,COG5301@2|Bacteria 2|Bacteria G cellulose 1,4-beta-cellobiosidase activity - - - - - - - - - - - - Collar,DUF3751,Phage_fiber_2 k59_184138_1 1692246.A0A0K1RL26_9CIRC 2.66e-06 52.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_184138_3 654929.REP_PCV1C 3.07e-18 90.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_59676_4 1618247.A0A0C5I2K0_9CIRC 7.22e-20 92.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_200764_2 247639.MGP2080_05417 5.54e-41 142.0 COG4627@1|root,COG4627@2|Bacteria,1N2HA@1224|Proteobacteria,1SJB1@1236|Gammaproteobacteria 1236|Gammaproteobacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Methyltransf_11 k59_200764_3 1297569.MESS2_1220034 6.99e-66 211.0 COG1442@1|root,COG1442@2|Bacteria,1QH4S@1224|Proteobacteria,2U9KQ@28211|Alphaproteobacteria,43JIY@69277|Phyllobacteriaceae 28211|Alphaproteobacteria M glycosyl transferase family 8 - - - - - - - - - - - - - k59_200764_4 1147150.K7PM60_9CAUD 6.12e-47 158.0 4QB1F@10239|Viruses,4QUYH@35237|dsDNA viruses no RNA stage,4QPSW@28883|Caudovirales,4QKPW@10699|Siphoviridae 10699|Siphoviridae S exonuclease activity - - - - - - - - - - - - - k59_200764_5 443152.MDG893_20584 1.09e-42 143.0 2DM6W@1|root,32UGB@2|Bacteria,1N425@1224|Proteobacteria,1SB1W@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF3168) - - - - - - - - - - - - DUF3168 k59_233612_2 497964.CfE428DRAFT_0770 3.29e-22 91.7 2DSBU@1|root,33FEQ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_101307_2 1379722.S5SY31_9CIRC 8.32e-19 85.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_185262_1 226185.EF_0330 1.78e-29 119.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4H9YP@91061|Bacilli,4B1S9@81852|Enterococcaceae 91061|Bacilli KL SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,SNF2_N k59_160253_1 743721.Psesu_1179 1.51e-16 83.6 2DSRK@1|root,33H6U@2|Bacteria,1P21N@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_152625_1 1129146.H2BDF8_9CAUD 1.19e-54 183.0 4QGDF@10239|Viruses,4R0KW@35237|dsDNA viruses no RNA stage,4QSIJ@28883|Caudovirales,4QMJY@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_28290_1 742767.HMPREF9456_03368 3.71e-49 188.0 COG5280@1|root,COG5280@2|Bacteria,4PNYN@976|Bacteroidetes,2FPMT@200643|Bacteroidia 976|Bacteroidetes S domain protein - - - - - - - - - - - - - k59_3371_1 988656.F0V6Y5_9CAUD 3.68e-06 48.1 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales,4QNBW@10744|Podoviridae 10744|Podoviridae S DNA helicase activity - - - - - - - - - - - - - k59_77717_1 1161927.I1TQ57_9CAUD 3.27e-11 76.6 4QB69@10239|Viruses,4QX5W@35237|dsDNA viruses no RNA stage,4QSF0@28883|Caudovirales,4QJ3A@10662|Myoviridae 10662|Myoviridae S peptidase activity - - - - - - - - - - - - - k59_119387_4 1120971.AUCA01000037_gene2900 9.19e-22 95.5 2CK39@1|root,32SBG@2|Bacteria,1V8KG@1239|Firmicutes,4HQKV@91061|Bacilli 91061|Bacilli S Phage gp6-like head-tail connector protein - - - - - - - - - - - - Phage_connect_1 k59_119387_6 631362.Thi970DRAFT_03408 3.77e-17 85.5 COG4627@1|root,COG4627@2|Bacteria,1N2HA@1224|Proteobacteria,1SJB1@1236|Gammaproteobacteria 1236|Gammaproteobacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Methyltransf_11 k59_102438_1 281687.CJA22623 1.68e-39 145.0 COG4227@1|root,2TJTB@2759|Eukaryota,39GN5@33154|Opisthokonta,3CKH1@33208|Metazoa,3E234@33213|Bilateria,40PR0@6231|Nematoda,1M787@119089|Chromadorea,415UE@6236|Rhabditida 33208|Metazoa L Domain of unknown function (DUF1738) - - - - - - - - - - - - DUF1738 k59_252456_1 202952.BBLI01000050_gene2977 6.14e-05 52.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,3NK54@468|Moraxellaceae 1236|Gammaproteobacteria L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3 k59_29595_1 99598.Cal7507_1583 6.01e-77 249.0 COG0305@1|root,COG0305@2|Bacteria,1G0R8@1117|Cyanobacteria,1HJAT@1161|Nostocales 1117|Cyanobacteria L Participates in initiation and elongation during chromosome replication dnaB GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3 k59_244254_1 1476888.X4Y7Z1_9CAUD 4.25e-48 165.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_86308_1 399741.Spro_3066 1.93e-22 102.0 COG0675@1|root,COG0675@2|Bacteria,1MUU0@1224|Proteobacteria,1RS1J@1236|Gammaproteobacteria,402WY@613|Serratia 1236|Gammaproteobacteria L Putative transposase DNA-binding domain Z012_11195 - - ko:K07496 - - - - ko00000 - - - HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon k59_252461_1 1453501.JELR01000001_gene2516 1.13e-47 176.0 COG4733@1|root,COG4926@1|root,COG4733@2|Bacteria,COG4926@2|Bacteria,1R77Q@1224|Proteobacteria,1S1WT@1236|Gammaproteobacteria,469QU@72275|Alteromonadaceae 1236|Gammaproteobacteria S Fibronectin type 3 domain - - - - - - - - - - - - - k59_186897_2 1072685.IX83_07085 1.35e-116 345.0 28HXV@1|root,2Z83C@2|Bacteria,1PJBP@1224|Proteobacteria,2W8RH@28216|Betaproteobacteria,3T5DR@506|Alcaligenaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_20285_1 598467.BrE312_3469 2.02e-31 124.0 COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,1RNE0@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Belongs to the 'phage' integrase family int - - - - - - - - - - - Arm-DNA-bind_3,Phage_integrase k59_261705_1 1028800.RG540_CH13810 2.06e-23 100.0 28MSK@1|root,2ZB0X@2|Bacteria,1R7CY@1224|Proteobacteria,2U2MY@28211|Alphaproteobacteria,4BJ92@82115|Rhizobiaceae 28211|Alphaproteobacteria S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_78990_1 1618248.A0A0C5IB82_9CIRC 3.42e-31 118.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_78990_3 1692250.A0A0K1RLR1_9CIRC 4.6e-75 234.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_5150_7 83406.HDN1F_35020 2.83e-126 398.0 COG3505@1|root,COG3505@2|Bacteria,1MVGD@1224|Proteobacteria,1RNGF@1236|Gammaproteobacteria,1J83J@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U TraM recognition site of TraD and TraG traD - - ko:K12071 - - - - ko00000,ko02044 3.A.7.11.1 - - TraG-D_C,TrwB_AAD_bind k59_29771_1 33898.JRHJ01000076_gene413 1.8e-14 80.1 COG1783@1|root,COG1783@2|Bacteria,2I8SC@201174|Actinobacteria 201174|Actinobacteria S Terminase-like family - - - - - - - - - - - - Terminase_3,Terminase_6,Terminase_6C k59_86422_2 1502851.FG93_05502 1.99e-59 191.0 COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,2TU8N@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_194580_4 1357732.A0A059PY39_9CAUD 2.6e-29 116.0 4QAQY@10239|Viruses,4QUWR@35237|dsDNA viruses no RNA stage,4QPIN@28883|Caudovirales,4QND6@10744|Podoviridae 10744|Podoviridae S KilA-N domain - - - - - - - - - - - - - k59_87684_1 521000.PROVRETT_05530 3.76e-10 59.7 COG3179@1|root,COG3179@2|Bacteria,1RE8K@1224|Proteobacteria,1S4U8@1236|Gammaproteobacteria,3Z9BP@586|Providencia 1236|Gammaproteobacteria S D-alanyl-D-alanine carboxypeptidase - - - - - - - - - - - - Peptidase_M15_4 k59_245729_1 1306990.BARG01000090_gene8970 6.31e-45 162.0 COG0847@1|root,COG0847@2|Bacteria,2ICSU@201174|Actinobacteria 201174|Actinobacteria L Exonuclease - - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T k59_21752_1 323098.Nwi_1615 1.17e-06 54.3 COG1511@1|root,COG5281@1|root,COG1511@2|Bacteria,COG5281@2|Bacteria,1MX2R@1224|Proteobacteria,2U3WK@28211|Alphaproteobacteria,3K1A2@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S tape measure protein - - - - - - - - - - - - Peptidase_M15_4,Tape_meas_lam_C k59_263274_1 536019.Mesop_3732 1.78e-42 157.0 COG0553@1|root,COG0553@2|Bacteria,1R7CK@1224|Proteobacteria,2U228@28211|Alphaproteobacteria,43I7K@69277|Phyllobacteriaceae 28211|Alphaproteobacteria KL DEAD-like helicases superfamily - - - - - - - - - - - - Helicase_C,N6_N4_Mtase k59_63129_1 749413.E5DV66_9VIRU 4.93e-07 54.7 4QB4T@10239|Viruses,4QVRD@35237|dsDNA viruses no RNA stage 10239|Viruses - - - - - - - - - - - - - - - k59_48189_1 643867.Ftrac_3748 7.68e-08 54.3 2DMPT@1|root,32SXV@2|Bacteria,4PKGT@976|Bacteroidetes,47R1K@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF3127) - - - - - - - - - - - - DUF3127 k59_7115_1 1096546.WYO_0201 6.19e-106 333.0 28P6A@1|root,2ZC10@2|Bacteria,1RBZE@1224|Proteobacteria,2UQEG@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_56067_1 665950.HMPREF1025_02007 5.64e-50 179.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_21755_1 1385658.U5KPZ6_9VIRU 2.42e-70 228.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_87688_1 1172188.KB911820_gene2847 6.68e-28 112.0 COG3567@1|root,COG3567@2|Bacteria,2H48H@201174|Actinobacteria 201174|Actinobacteria S Phage portal protein, SPP1 Gp6-like - - - - - - - - - - - - Phage_prot_Gp6 k59_72556_2 1197951.I6RT34_9CAUD 1.63e-96 296.0 4QGAG@10239|Viruses,4R0KB@35237|dsDNA viruses no RNA stage,4QUA4@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_223093_1 55207.KP22_04110 4.14e-05 52.4 2B5CE@1|root,31Y6M@2|Bacteria,1RIPZ@1224|Proteobacteria,1S7Y0@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_172529_2 160488.PP_2293 1.18e-65 218.0 COG5410@1|root,COG5410@2|Bacteria,1N0W2@1224|Proteobacteria,1S03G@1236|Gammaproteobacteria 1236|Gammaproteobacteria K chromosome segregation - - - - - - - - - - - - - k59_205442_1 1385658.U5KPZ6_9VIRU 1.01e-52 185.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_31578_3 1379710.S5TNC2_9CIRC 1.74e-14 77.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_245735_2 1196322.A370_05742 9.74e-14 71.2 2C6KN@1|root,32Y69@2|Bacteria,1VANX@1239|Firmicutes,24MNG@186801|Clostridia,36KM4@31979|Clostridiaceae 186801|Clostridia S VRR-NUC domain - - - - - - - - - - - - VRR_NUC k59_7123_1 633148.Tagg_0328 4.46e-22 103.0 COG1204@1|root,arCOG00553@2157|Archaea,2XPUH@28889|Crenarchaeota 28889|Crenarchaeota L DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks hel308 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - ko:K03726 - - - - ko00000,ko01000 - - - DEAD,HHH_5,Helicase_C k59_230002_1 113355.CM001775_gene2574 2.67e-15 79.7 COG0863@1|root,COG0863@2|Bacteria,1G4CX@1117|Cyanobacteria 1117|Cyanobacteria L DNA methylase - - 2.1.1.113 ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_230002_2 411467.BACCAP_00123 3.4e-09 58.9 COG0338@1|root,COG0338@2|Bacteria,1TRDX@1239|Firmicutes,25E75@186801|Clostridia,26CNS@186813|unclassified Clostridiales 186801|Clostridia L D12 class N6 adenine-specific DNA methyltransferase dam - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 k59_245862_2 864702.OsccyDRAFT_0719 4.13e-36 129.0 COG0817@1|root,COG0817@2|Bacteria,1G6YP@1117|Cyanobacteria 1117|Cyanobacteria L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group - - - - - - - - - - - - - k59_245862_3 1502852.FG94_04984 4.16e-10 59.3 2BZTS@1|root,33131@2|Bacteria,1NBBP@1224|Proteobacteria,2W4DH@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_245862_5 172045.KS04_14935 4.58e-23 102.0 2AF6W@1|root,3155U@2|Bacteria,4PJE5@976|Bacteroidetes,1IBGX@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_245862_6 1123508.JH636441_gene3587 3.26e-49 171.0 COG1484@1|root,COG1484@2|Bacteria 2|Bacteria L DNA-dependent DNA replication dnaC - - ko:K02315 - - - - ko00000,ko03032 - - - IstB_IS21 k59_140663_3 742740.HMPREF9474_02262 5.26e-17 85.9 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia,221IX@1506553|Lachnoclostridium 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_140665_1 1304275.C41B8_05368 7.12e-26 108.0 28S81@1|root,2ZEJD@2|Bacteria,1RCNN@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_197445_1 1410653.JHVC01000013_gene3685 6.85e-05 48.1 COG4383@1|root,COG4383@2|Bacteria,1U5A7@1239|Firmicutes,258CF@186801|Clostridia,36TMY@31979|Clostridiaceae 186801|Clostridia S Protein of unknown function (DUF935) - - - - - - - - - - - - DUF935 k59_213717_1 1234888.K0A2J2_9VIRU 8.34e-123 370.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_181705_1 1692253.A0A0K1RLM4_9CIRC 1.14e-26 114.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_15183_2 1437448.AZRT01000037_gene3265 4.63e-14 77.4 COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,2TSTN@28211|Alphaproteobacteria,1J2MA@118882|Brucellaceae 28211|Alphaproteobacteria K ParB-like nuclease domain parB - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_132548_1 10872.VG301_BPPF3 4.84e-39 145.0 4QBME@10239|Viruses,4QUKP@29258|ssDNA viruses,4QP4G@10860|Inoviridae 10860|Inoviridae S Zonular occludens toxin (Zot) - - - - - - - - - - - - - k59_197685_2 1609634.A0A0C5AFV4_9VIRU 4.97e-09 57.4 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_181718_4 313596.RB2501_01256 7.75e-40 136.0 COG3108@1|root,COG3108@2|Bacteria,4NV14@976|Bacteroidetes,1I63W@117743|Flavobacteriia 976|Bacteroidetes S Peptidase M15 - - - - - - - - - - - - Peptidase_M15_3 k59_15199_1 1250232.JQNJ01000001_gene2887 9.64e-06 48.1 2DSMC@1|root,33GP4@2|Bacteria,4P61U@976|Bacteroidetes 976|Bacteroidetes S Domain of unknown function (DUF4326) - - - - - - - - - - - - DUF4326 k59_15199_2 1210884.HG799462_gene8561 1.29e-35 135.0 COG1397@1|root,COG1397@2|Bacteria,2IZFE@203682|Planctomycetes 203682|Planctomycetes O ADP-ribosylglycohydrolase - - - - - - - - - - - - ADP_ribosyl_GH k59_174252_1 575540.Isop_2440 2.51e-81 252.0 28HHC@1|root,2Z7T2@2|Bacteria,2J15Z@203682|Planctomycetes 203682|Planctomycetes S AAA domain - - - - - - - - - - - - AAA_24 k59_174252_3 575540.Isop_2441 3.26e-45 151.0 2CEI6@1|root,2ZED5@2|Bacteria,2J3S1@203682|Planctomycetes 203682|Planctomycetes S Protein of unknown function (DUF669) - - - - - - - - - - - - DUF669 k59_99817_2 1692255.A0A0K1RL52_9CIRC 1.36e-102 309.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_83241_9 49964.Q94MR7_9CAUD 9.29e-97 311.0 4QERB@10239|Viruses,4R014@35237|dsDNA viruses no RNA stage,4QTGJ@28883|Caudovirales,4QNZG@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_25278_1 1410653.JHVC01000014_gene3333 1.29e-21 94.4 COG3409@1|root,COG3409@2|Bacteria,1UIRK@1239|Firmicutes,24KJ0@186801|Clostridia,36JPU@31979|Clostridiaceae 186801|Clostridia M N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - Amidase_2,PG_binding_1 k59_99823_1 1105383.G8E3X2_9CIRC 5.13e-12 72.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_91529_2 1051675.G0YQJ1_9CAUD 1.21e-79 246.0 4QGM6@10239|Viruses,4QYNV@35237|dsDNA viruses no RNA stage,4QRH4@28883|Caudovirales,4QP0P@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_91529_3 1051675.G0YQJ0_9CAUD 1.48e-292 809.0 4QEFX@10239|Viruses,4QYYG@35237|dsDNA viruses no RNA stage,4QRRV@28883|Caudovirales,4QNTK@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_91529_4 1051675.G0YQI9_9CAUD 1.07e-55 184.0 4QF0B@10239|Viruses,4QX8P@35237|dsDNA viruses no RNA stage,4QSJT@28883|Caudovirales,4QNNK@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_149508_1 352165.HMPREF7215_2558 1.42e-10 68.6 COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria 2|Bacteria L DNA primase activity - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - AAA_25,DUF3987,DnaB_C,Toprim_2,Toprim_4 k59_33540_1 484019.THA_826 1.06e-32 134.0 COG0305@1|root,COG0305@2|Bacteria,2GC55@200918|Thermotogae 200918|Thermotogae L Participates in initiation and elongation during chromosome replication - - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_16869_1 494416.AYXN01000012_gene1178 1.45e-80 252.0 COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,1RMYA@1236|Gammaproteobacteria,3NJRY@468|Moraxellaceae 1236|Gammaproteobacteria F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine purF GO:0003674,GO:0003824,GO:0004044,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009165,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019752,GO:0034641,GO:0034654,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - iAF1260.b2312,iB21_1397.B21_02197,iBWG_1329.BWG_2086,iECBD_1354.ECBD_1347,iECB_1328.ECB_02237,iECDH10B_1368.ECDH10B_2474,iECDH1ME8569_1439.ECDH1ME8569_2250,iECD_1391.ECD_02237,iECIAI1_1343.ECIAI1_2389,iECO103_1326.ECO103_2776,iECO111_1330.ECO111_3060,iECO26_1355.ECO26_3300,iECW_1372.ECW_m2501,iEKO11_1354.EKO11_1453,iETEC_1333.ETEC_2448,iEcDH1_1363.EcDH1_1344,iEcE24377_1341.EcE24377A_2606,iEcolC_1368.EcolC_1340,iJO1366.b2312,iJR904.b2312,iSF_1195.SF2388,iSFxv_1172.SFxv_2633,iSSON_1240.SSON_2370,iS_1188.S2523,iSbBS512_1146.SbBS512_E2690,iUMNK88_1353.UMNK88_2863,iWFL_1372.ECW_m2501,iY75_1357.Y75_RS12125 GATase_6,Pribosyltran k59_257476_2 1197951.I6R9K8_9CAUD 7.61e-129 377.0 4QFIC@10239|Viruses,4QXG2@35237|dsDNA viruses no RNA stage,4QTVA@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_257476_5 1197951.I6S2A9_9CAUD 1.4e-185 543.0 4QCM5@10239|Viruses,4QVZY@35237|dsDNA viruses no RNA stage,4QQFH@28883|Caudovirales 28883|Caudovirales S Bacteriophage head to tail connecting protein - GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019028,GO:0019058,GO:0019068,GO:0019072,GO:0019073,GO:0032991,GO:0044403,GO:0044419,GO:0044423,GO:0046798,GO:0051704 - - - - - - - - - - - k59_42080_2 1165094.RINTHH_3920 1.11e-62 207.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_42080_4 1385658.U5KPZ6_9VIRU 2.86e-117 359.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_75290_4 35703.DQ02_13795 8.44e-34 125.0 COG3926@1|root,COG3926@2|Bacteria,1QV3R@1224|Proteobacteria,1T276@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Glycosyl hydrolase 108 - - - - - - - - - - - - CHAP k59_108380_1 1234888.K0A2J2_9VIRU 1.06e-85 273.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_83492_1 312309.VF_0074 1.03e-11 76.6 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1XUAZ@135623|Vibrionales 135623|Vibrionales L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_42082_1 272560.BPSL2061 2.29e-20 95.9 COG0457@1|root,COG0457@2|Bacteria,1MUZK@1224|Proteobacteria,2VJNV@28216|Betaproteobacteria,1K0WR@119060|Burkholderiaceae 28216|Betaproteobacteria M repeat-containing protein - - - - - - - - - - - - Glyco_transf_9,TPR_1,TPR_11,TPR_16,TPR_2,TPR_4,TPR_8 k59_149875_1 1618247.A0A0C5IMK7_9CIRC 1.63e-08 60.1 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_668_1 563192.HMPREF0179_03460 2.02e-50 180.0 COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1PZ6S@1224|Proteobacteria,42YZ3@68525|delta/epsilon subdivisions,2WU0W@28221|Deltaproteobacteria,2MAW9@213115|Desulfovibrionales 28221|Deltaproteobacteria L Toprim-like - - - - - - - - - - - - DnaB_C,Toprim_2 k59_58616_1 1123326.JFBL01000002_gene1658 4.18e-30 130.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2YMQV@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_141641_3 462590.A9J580_BPPYU 1.27e-181 523.0 4QB49@10239|Viruses,4QUZD@35237|dsDNA viruses no RNA stage,4QPU2@28883|Caudovirales,4QKRQ@10699|Siphoviridae 10699|Siphoviridae S Domain of unknown function (DUF4055) - - - - - - - - - - - - - k59_8932_1 1524880.A0A076G6J2_9VIRU 1.49e-67 222.0 4QD9Y@10239|Viruses 10239|Viruses S Pfam:Terminase_6C - - - - - - - - - - - - - k59_33928_1 488538.SAR116_0382 9.03e-58 201.0 28S81@1|root,2ZEJD@2|Bacteria,1RCNN@1224|Proteobacteria,2U6Z0@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_50402_1 261726.A2I303_9CAUD 5.79e-18 82.4 4QBQJ@10239|Viruses,4QVNC@35237|dsDNA viruses no RNA stage,4QPZ3@28883|Caudovirales,4QIN9@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_207865_1 582345.D6RRL6_BPKPP 2.06e-76 240.0 4QAUS@10239|Viruses,4QURX@35237|dsDNA viruses no RNA stage,4QQ2S@28883|Caudovirales 28883|Caudovirales S flavin adenine dinucleotide binding - - - - - - - - - - - - - k59_116797_1 313606.M23134_01127 1.61e-05 55.5 COG3204@1|root,COG3211@1|root,COG4935@1|root,COG3204@2|Bacteria,COG3211@2|Bacteria,COG4935@2|Bacteria,4NJ5V@976|Bacteroidetes,47JPA@768503|Cytophagia 976|Bacteroidetes G Bacterial protein of unknown function (DUF839) - - - ko:K07093 - - - - ko00000 - - - DUF839 k59_83527_5 1234888.K0A2J2_9VIRU 2.43e-147 437.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_175011_1 1692252.A0A0K1RL35_9CIRC 1.53e-94 286.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_175011_2 1692252.A0A0K1RLN6_9CIRC 2.97e-28 117.0 4QCY8@10239|Viruses,4QUMD@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_42676_1 1692253.A0A0K1RLM4_9CIRC 1.67e-41 154.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_84027_1 1385658.U5KPZ6_9VIRU 5.25e-61 207.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_75935_1 153721.MYP_2462 1.11e-24 114.0 COG2730@1|root,COG3325@1|root,COG3469@1|root,COG5295@1|root,COG2730@2|Bacteria,COG3325@2|Bacteria,COG3469@2|Bacteria,COG5295@2|Bacteria,4NF6Q@976|Bacteroidetes,47KN7@768503|Cytophagia 976|Bacteroidetes GUW candidate b-glycosidase, glycoside hydrolase family 8 protein - - - - - - - - - - - - Beta_helix,Big_3_3,M60-like_N,NosD,Peptidase_M60 k59_158561_2 101570.Q5G8Y7_9CAUD 2.27e-40 148.0 4QEFV@10239|Viruses,4QYS7@35237|dsDNA viruses no RNA stage,4QRRT@28883|Caudovirales,4QMIB@10699|Siphoviridae 10699|Siphoviridae S Phage terminase large subunit - - - - - - - - - - - - - k59_150611_2 1340826.S5Y506_9CAUD 1.02e-37 139.0 4QARC@10239|Viruses,4QV4E@35237|dsDNA viruses no RNA stage,4QPDS@28883|Caudovirales,4QKXX@10699|Siphoviridae 10699|Siphoviridae S RNase_H superfamily - - - - - - - - - - - - - k59_150611_3 329254.Q2NPF7_9CAUD 2.49e-36 129.0 4QB0U@10239|Viruses,4QZQJ@35237|dsDNA viruses no RNA stage,4QR5X@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_142383_1 500637.PROVRUST_07448 3.94e-21 98.2 COG1061@1|root,COG1061@2|Bacteria,1MV9F@1224|Proteobacteria,1RNAN@1236|Gammaproteobacteria,3Z7NF@586|Providencia 1236|Gammaproteobacteria KL Helicase C-terminal domain protein yejH GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042221,GO:0042493,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051301,GO:0051716,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - ko:K19789 - - - - ko00000,ko03400 - - - Helicase_C,ResIII k59_108982_2 713586.KB900536_gene449 3.29e-08 56.6 COG0739@1|root,COG0739@2|Bacteria,1MY2X@1224|Proteobacteria,1RMYN@1236|Gammaproteobacteria 1236|Gammaproteobacteria M peptidase - - - - - - - - - - - - Peptidase_M23 k59_183584_1 2003327.CAPSD_BPCHP 2.24e-90 295.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_258537_1 1121459.AQXE01000001_gene2774 1.02e-36 144.0 COG5108@1|root,COG5108@2|Bacteria,1PIWB@1224|Proteobacteria,42YXG@68525|delta/epsilon subdivisions,2WU1V@28221|Deltaproteobacteria,2M9ED@213115|Desulfovibrionales 28221|Deltaproteobacteria K DNA-dependent RNA polymerase - - - - - - - - - - - - RNA_pol,RPOL_N k59_92486_1 460265.Mnod_4282 1.4e-18 90.9 COG3740@1|root,COG3740@2|Bacteria,1QVIJ@1224|Proteobacteria,2TVIM@28211|Alphaproteobacteria,1JX89@119045|Methylobacteriaceae 28211|Alphaproteobacteria S PFAM peptidase U35 phage prohead HK97 - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_183585_1 105154.Q9MBU6_9VIRU 1.83e-51 181.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_92487_1 158500.BV97_03964 1.2e-55 190.0 COG5323@1|root,COG5323@2|Bacteria,1MW8S@1224|Proteobacteria,2TREI@28211|Alphaproteobacteria,2K2BG@204457|Sphingomonadales 204457|Sphingomonadales S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_67554_1 1234888.K0A2J2_9VIRU 1.34e-42 153.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_158566_1 202954.BBNK01000009_gene1263 1.22e-43 148.0 COG3926@1|root,COG3926@2|Bacteria,1RKWV@1224|Proteobacteria,1SYTS@1236|Gammaproteobacteria,3NJ0N@468|Moraxellaceae 1236|Gammaproteobacteria S Predicted Peptidoglycan domain - - - - - - - - - - - - Glyco_hydro_108,PG_binding_3 k59_134016_2 882082.SaccyDRAFT_2319 0.000464 50.4 COG0739@1|root,COG3409@1|root,COG0739@2|Bacteria,COG3409@2|Bacteria,2GU2Q@201174|Actinobacteria,4E268@85010|Pseudonocardiales 201174|Actinobacteria M Peptidase family M23 - - - - - - - - - - - - PG_binding_1,Peptidase_M23 k59_125768_1 1161935.H9D1H6_9CAUD 6.51e-06 54.7 4QGAG@10239|Viruses,4R0KB@35237|dsDNA viruses no RNA stage,4QUA4@28883|Caudovirales,4QNFP@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_109493_3 1385658.U5KPZ6_9VIRU 2.05e-140 423.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_184076_2 1618247.A0A0C5IMK7_9CIRC 9.22e-07 56.6 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_84470_2 1234888.K0A2R8_9VIRU 7.65e-44 158.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_84470_5 1234888.K0A2J2_9VIRU 7.4e-128 387.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_242125_2 1096546.WYO_0201 1.56e-147 443.0 28P6A@1|root,2ZC10@2|Bacteria,1RBZE@1224|Proteobacteria,2UQEG@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_259086_1 460265.Mnod_4078 4.62e-29 123.0 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,2U6BJ@28211|Alphaproteobacteria,1JZ7Y@119045|Methylobacteriaceae 28211|Alphaproteobacteria S TIGRFAM phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_158988_1 1589297.A0A0B5H2N7_9CAUD 8.21e-48 181.0 4QAXA@10239|Viruses,4QQ1A@28883|Caudovirales,4QNU7@10744|Podoviridae 10744|Podoviridae S metallopeptidase activity - - - - - - - - - - - - - k59_225864_1 1231190.NA8A_00010 9.94e-19 89.0 COG2755@1|root,COG2755@2|Bacteria 2|Bacteria E lipolytic protein G-D-S-L family - - - - - - - - - - - - Cadherin,Calx-beta,FG-GAP,Flg_new,Laminin_G_3,Lipase_GDSL_2,M60-like_N,PA14,Peptidase_M60 k59_92964_2 1150989.H6WXH4_9CAUD 3.09e-25 99.0 4QB6G@10239|Viruses,4QVYX@35237|dsDNA viruses no RNA stage,4QQS8@28883|Caudovirales 28883|Caudovirales S Peptidase M15 - - - - - - - - - - - - - k59_118175_2 1034943.BN1094_00476 4.54e-23 101.0 COG1089@1|root,COG1089@2|Bacteria,1MUX0@1224|Proteobacteria,1RMIY@1236|Gammaproteobacteria,1JDXX@118969|Legionellales 118969|Legionellales H Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose gmd - 4.2.1.47 ko:K01711 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R00888 RC00402 ko00000,ko00001,ko01000 - - - GDP_Man_Dehyd k59_167779_3 335543.Sfum_3184 1.26e-54 190.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,42M7X@68525|delta/epsilon subdivisions,2WJCA@28221|Deltaproteobacteria,2MQ50@213462|Syntrophobacterales 28221|Deltaproteobacteria L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_34986_3 1242864.D187_000671 8.6e-05 45.4 COG5184@1|root,COG5184@2|Bacteria,1RD7W@1224|Proteobacteria 1224|Proteobacteria DZ Regulator of chromosome condensation (RCC1) repeat - - - - - - - - - - - - RCC1,RCC1_2 k59_175672_2 279238.Saro_2987 1.56e-97 295.0 2CYA9@1|root,32T3V@2|Bacteria,1RGRN@1224|Proteobacteria,2U90D@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_68058_1 1129368.SMIPMB4A_v3c3050 2.72e-12 76.3 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,3WT2S@544448|Tenericutes 544448|Tenericutes L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A k59_167783_1 438482.A4ZRC7_9CAUD 0.000191 49.7 4QNBD@10744|Podoviridae 10744|Podoviridae S outer membrane - - - - - - - - - - - - - k59_184151_1 556269.ACDQ01000006_gene1592 2.86e-54 186.0 2CENN@1|root,32VYV@2|Bacteria,1N4RC@1224|Proteobacteria,2W1J6@28216|Betaproteobacteria,476WV@75682|Oxalobacteraceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_151299_2 84588.SYNW0448 1.73e-08 59.3 COG2089@1|root,COG2089@2|Bacteria,1G4IG@1117|Cyanobacteria,1GZZR@1129|Synechococcus 1117|Cyanobacteria M acid synthetase spsE - 2.5.1.101,2.5.1.56 ko:K01654,ko:K18430 ko00520,ko01100,map00520,map01100 - R01804,R04435,R10304 RC00159 ko00000,ko00001,ko01000 - - - AP_endonuc_2,NeuB,SAF k59_118579_1 1692249.A0A0K1RL40_9CIRC 1.22e-36 135.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_218162_2 1414739.W6AT00_9CAUD 3.84e-31 125.0 4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - GO:0008150,GO:0044403,GO:0044409,GO:0044411,GO:0044419,GO:0051701,GO:0051704,GO:0051828,GO:0051830,GO:0085027 - - - - - - - - - - - k59_101536_1 1618236.A0A0C5IB23_9CIRC 7.88e-18 89.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_159279_1 428125.CLOLEP_01375 1.7e-96 315.0 2EWZQ@1|root,33QB0@2|Bacteria,1V0T1@1239|Firmicutes,249Z2@186801|Clostridia,3WNBH@541000|Ruminococcaceae 186801|Clostridia S DNA polymerase type-B family - - - - - - - - - - - - - k59_168099_1 1692250.A0A0K1RLR1_9CIRC 2.75e-54 179.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_109866_2 1096546.WYO_0193 1.75e-15 76.6 28JC4@1|root,2Z96S@2|Bacteria,1RI8W@1224|Proteobacteria 1224|Proteobacteria S P22 coat protein-protein 5 domain protein - - - - - - - - - - - - - k59_151578_1 1177181.T9A_00235 2.29e-52 183.0 COG4128@1|root,COG4128@2|Bacteria,1RCY8@1224|Proteobacteria,1S4JQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Zonular occludens toxin (Zot) - - - ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko02042 - - - Zot k59_233799_1 1161401.ASJA01000008_gene1658 9.87e-09 60.5 2CJWY@1|root,33MF9@2|Bacteria,1NKUU@1224|Proteobacteria,2UMVZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_233799_2 1388763.O165_010685 8.28e-112 337.0 COG2369@1|root,COG2369@2|Bacteria,1PUNX@1224|Proteobacteria,1RUNF@1236|Gammaproteobacteria,1YX7I@136845|Pseudomonas putida group 1236|Gammaproteobacteria S Phage Mu protein F like protein - - - - - - - - - - - - Phage_Mu_F k59_233799_3 1117958.PE143B_0129530 1.57e-19 90.5 28KYW@1|root,2ZAE8@2|Bacteria,1MX3D@1224|Proteobacteria,1RQQR@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4055) - - - - - - - - - - - - DUF4055 k59_143362_1 1077285.AGDG01000027_gene1631 2.81e-06 55.1 COG5434@1|root,COG5434@2|Bacteria,4NIPA@976|Bacteroidetes,2FY8I@200643|Bacteroidia,4AW1J@815|Bacteroidaceae 976|Bacteroidetes G Belongs to the glycosyl hydrolase 28 family - - - - - - - - - - - - Alginate_lyase,Glyco_hydro_28 k59_242402_1 1279015.KB908455_gene1428 5.43e-69 229.0 COG0740@1|root,COG0740@2|Bacteria,1MUQ9@1224|Proteobacteria,1RRQA@1236|Gammaproteobacteria,1Y67D@135624|Aeromonadales 135624|Aeromonadales OU Clp protease - - - - - - - - - - - - CLP_protease k59_59949_2 167542.P9515_09941 3.63e-09 56.2 COG1694@1|root,COG1694@2|Bacteria,1G25W@1117|Cyanobacteria,1MMRE@1212|Prochloraceae 1117|Cyanobacteria S Alternative locus ID - - - - - - - - - - - - MazG k59_2526_2 145579.B_BPPHM 2.89e-32 119.0 4QDBB@10239|Viruses,4QUM0@29258|ssDNA viruses,4QP4D@10841|Microviridae 10841|Microviridae S Chlamydia-phage Chp2 scaffold (Chlamy_scaf) - - - - - - - - - - - - - k59_184390_1 1262513.K7Z9P9_9CAUD 1.98e-20 91.3 4QB86@10239|Viruses,4QWTC@35237|dsDNA viruses no RNA stage,4QQ18@28883|Caudovirales,4QK1K@10662|Myoviridae 10662|Myoviridae S DNA primase activity - - - - - - - - - - - - - k59_184390_2 753084.F4YCR0_9CAUD 1.78e-73 243.0 4QAIK@10239|Viruses,4QUPH@35237|dsDNA viruses no RNA stage,4QPEB@28883|Caudovirales,4QKNC@10699|Siphoviridae 10699|Siphoviridae S hydrolase activity - - - - - - - - - - - - - k59_259454_1 525263.HMPREF0298_1810 2.69e-17 84.3 COG2197@1|root,COG2197@2|Bacteria,2IKHB@201174|Actinobacteria 201174|Actinobacteria KT Replicase family - - - - - - - - - - - - PriCT_1,Replicase k59_35268_1 1234888.K0A2J2_9VIRU 6.61e-40 148.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_68376_1 1147.D082_13490 1.57e-46 160.0 COG3179@1|root,COG3179@2|Bacteria,1G1SC@1117|Cyanobacteria 1117|Cyanobacteria M PFAM Chitinase class I - - - - - - - - - - - - Glyco_hydro_19,PG_binding_1,Peptidase_M74,VanY k59_201498_2 1385658.U5KPZ6_9VIRU 2.16e-52 182.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_52504_2 1128421.JAGA01000004_gene2630 6.75e-32 133.0 2D784@1|root,32TNH@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_2904_2 1379725.S5SYG4_9CIRC 1.84e-15 81.6 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_135410_2 444875.E3SMH9_9CAUD 1.51e-40 147.0 4QAM2@10239|Viruses,4QV3W@35237|dsDNA viruses no RNA stage,4QPGK@28883|Caudovirales,4QNW0@10744|Podoviridae 10744|Podoviridae S exonuclease activity - GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 - - - - - - - - - - - k59_110444_3 1234888.K0A2J2_9VIRU 3.47e-110 339.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_110527_1 1618248.A0A0C5IB82_9CIRC 1.27e-10 66.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_192822_1 1046714.AMRX01000006_gene3178 5.53e-10 69.3 COG4733@1|root,COG4733@2|Bacteria,1NCQ4@1224|Proteobacteria,1SEXE@1236|Gammaproteobacteria,46BS4@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF1983) - - - - - - - - - - - - DUF1983,DUF3672 k59_68897_1 1141137.K4F7X5_9CAUD 2.38e-20 94.0 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales,4QNBW@10744|Podoviridae 10744|Podoviridae S DNA helicase activity - - - - - - - - - - - - - k59_110532_1 1217710.F969_00036 2.3e-35 136.0 COG5565@1|root,COG5565@2|Bacteria,1R6R3@1224|Proteobacteria,1RY0J@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C k59_218872_2 1096546.WYO_0656 2.44e-18 83.2 COG1051@1|root,COG1051@2|Bacteria 2|Bacteria F GDP-mannose mannosyl hydrolase activity - - - - - - - - - - - - NUDIX k59_218872_4 1220601.L7TML1_9CAUD 2.85e-41 147.0 4QFUK@10239|Viruses,4QYFH@35237|dsDNA viruses no RNA stage,4QRPY@28883|Caudovirales,4QIG8@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_52606_1 13333.ERN14768 3.11e-44 162.0 28HK1@1|root,2QPXS@2759|Eukaryota,37NXW@33090|Viridiplantae,3GF00@35493|Streptophyta 35493|Streptophyta L Twinkle homolog protein chloroplastic - GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003697,GO:0003824,GO:0003896,GO:0003899,GO:0004003,GO:0004386,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016043,GO:0016070,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032392,GO:0032508,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051276,GO:0055086,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090407,GO:0097159,GO:0097747,GO:0140097,GO:0140098,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - DnaB_C,Toprim_4 k59_250971_3 1234888.K0A2J2_9VIRU 9.1e-147 435.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_131629_2 1280001.BAOA01000115_gene124 5.43e-18 82.0 COG0645@1|root,COG0645@2|Bacteria,1N1S8@1224|Proteobacteria,1SEDC@1236|Gammaproteobacteria,1XXSN@135623|Vibrionales 135623|Vibrionales S AAA domain - - - - - - - - - - - - AAA_33 k59_173323_1 1234888.K0A2J2_9VIRU 1.19e-86 282.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_140101_1 1121459.AQXE01000001_gene2739 1.62e-48 172.0 COG5410@1|root,COG5410@2|Bacteria,1N0W2@1224|Proteobacteria,42YNM@68525|delta/epsilon subdivisions,2WU2R@28221|Deltaproteobacteria,2MAIS@213115|Desulfovibrionales 28221|Deltaproteobacteria K chromosome segregation - - - - - - - - - - - - - k59_180945_4 754476.Q7A_921 1.19e-49 159.0 COG2944@1|root,COG2944@2|Bacteria,1MZGM@1224|Proteobacteria,1SB1E@1236|Gammaproteobacteria,461HY@72273|Thiotrichales 72273|Thiotrichales K Helix-turn-helix XRE-family like proteins - - - ko:K07726 - - - - ko00000,ko03000 - - - - k59_180945_5 1485545.JQLW01000010_gene1515 7.07e-52 166.0 COG4737@1|root,COG4737@2|Bacteria,1N7N5@1224|Proteobacteria 1224|Proteobacteria K Cytotoxic translational repressor of toxin-antitoxin stability system relE - - - - - - - - - - - RelE k59_115477_1 145579.CAPSD_BPPHM 4.8e-37 142.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_131689_3 1692249.A0A0K1RLN8_9CIRC 7.02e-26 107.0 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_49131_2 716928.AJQT01000109_gene1217 1.87e-12 66.2 2FEUE@1|root,346TC@2|Bacteria,1MZPB@1224|Proteobacteria,2UC4Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_223907_3 1502851.FG93_01114 3.85e-97 324.0 COG3170@1|root,COG3170@2|Bacteria,1PMRN@1224|Proteobacteria,2VC7S@28211|Alphaproteobacteria,3K5GP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria NU Tfp pilus assembly protein FimV - - - - - - - - - - - - - k59_223907_4 78245.Xaut_3704 8.35e-174 502.0 COG5323@1|root,COG5323@2|Bacteria,1MW8S@1224|Proteobacteria,2TREI@28211|Alphaproteobacteria,3EYR8@335928|Xanthobacteraceae 28211|Alphaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_180950_2 1347393.HG726020_gene1832 6.12e-07 55.1 COG4373@1|root,COG4373@2|Bacteria,4NI4T@976|Bacteroidetes,2FNH0@200643|Bacteroidia,4AT86@815|Bacteroidaceae 976|Bacteroidetes S Mu-like prophage FluMu protein gp28 - - - - - - - - - - - - - k59_106055_2 1692249.A0A0K1RL40_9CIRC 9.13e-39 144.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_63755_1 794903.OPIT5_06130 2.24e-18 82.8 COG0270@1|root,COG0270@2|Bacteria 2|Bacteria L DNA (cytosine-5-)-methyltransferase activity ydiP - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_230730_1 1618237.A0A0C5IMG6_9CIRC 2.62e-38 144.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_132291_2 478749.BRYFOR_08514 5.98e-40 136.0 2ARVA@1|root,31H70@2|Bacteria,1V7JT@1239|Firmicutes,24JPE@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - HK97-gp10_like k59_57409_1 145579.C_BPPHM 2.04e-29 107.0 4QCC5@10239|Viruses,4QUKW@29258|ssDNA viruses,4QP4C@10841|Microviridae 10841|Microviridae S viral process - - - - - - - - - - - - - k59_124280_1 1217810.I7EWC8_9CAUD 4.28e-17 87.0 4QASG@10239|Viruses,4QZZU@35237|dsDNA viruses no RNA stage,4QT37@28883|Caudovirales,4QNUJ@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_255357_1 1003200.AXXA_28025 3.29e-105 327.0 COG0507@1|root,COG5362@1|root,COG0507@2|Bacteria,COG5362@2|Bacteria,1R90H@1224|Proteobacteria,2W8BI@28216|Betaproteobacteria,3T6FT@506|Alcaligenaceae 28216|Betaproteobacteria L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD - - - - - - - - - - - - - k59_181585_2 273526.SMDB11_2873 7.89e-05 49.3 COG3108@1|root,COG3108@2|Bacteria,1RICX@1224|Proteobacteria,1S6D5@1236|Gammaproteobacteria,4039B@613|Serratia 1236|Gammaproteobacteria S D-alanyl-D-alanine carboxypeptidase - - - ko:K17733 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M15_4 k59_238485_2 1074309.G1JX92_9CAUD 2.8e-11 60.1 4QF4C@10239|Viruses,4QXEM@35237|dsDNA viruses no RNA stage,4QST2@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_246889_2 1692250.A0A0K1RLR1_9CIRC 3.85e-29 112.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_174027_2 1105367.CG50_10630 8.56e-13 73.9 COG2911@1|root,COG5281@1|root,COG5283@1|root,COG2911@2|Bacteria,COG5281@2|Bacteria,COG5283@2|Bacteria,1QU6S@1224|Proteobacteria,2TXGV@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Lambda phage tail tape-measure protein (Tape_meas_lam_C) - - - - - - - - - - - - Tape_meas_lam_C k59_140683_1 1089551.KE386572_gene1273 2.28e-29 124.0 COG4122@1|root,COG4122@2|Bacteria,1REAM@1224|Proteobacteria,2UPT1@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Methyltransferase domain - - - - - - - - - - - - Methyltransf_24 k59_132301_2 1121937.AUHJ01000007_gene1934 1.81e-35 127.0 2DICG@1|root,302RI@2|Bacteria,1PVSB@1224|Proteobacteria,1STCY@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_116022_3 870967.VIS19158_03906 1.19e-10 63.2 2DMPB@1|root,32SV8@2|Bacteria,1NHUE@1224|Proteobacteria,1SIKI@1236|Gammaproteobacteria,1XY3E@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k59_14982_1 1507.HMPREF0262_02449 5.35e-17 85.9 COG0249@1|root,COG0553@1|root,COG0827@1|root,COG3170@1|root,COG4646@1|root,COG0249@2|Bacteria,COG0553@2|Bacteria,COG0827@2|Bacteria,COG3170@2|Bacteria,COG4646@2|Bacteria,1TPQA@1239|Firmicutes,2491X@186801|Clostridia,36G7C@31979|Clostridiaceae 186801|Clostridia KL SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,N6_Mtase,ResIII,SNF2_N k59_156988_1 2003327.CAPSD_BPCHP 1.67e-108 340.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_190716_3 1031288.AXAA01000008_gene1301 4.09e-05 52.8 COG3409@1|root,COG3773@1|root,COG3409@2|Bacteria,COG3773@2|Bacteria,1TRFW@1239|Firmicutes,24912@186801|Clostridia,36EDT@31979|Clostridiaceae 186801|Clostridia M Cell wall hydrolase sleB - 3.5.1.28 ko:K01449 - - R04112 RC00064,RC00141 ko00000,ko01000 - - - Hydrolase_2,PG_binding_1 k59_213860_1 446470.Snas_6269 1.4e-12 69.3 COG0863@1|root,COG0863@2|Bacteria,2I9DJ@201174|Actinobacteria 201174|Actinobacteria L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.113,2.1.1.72 ko:K00571,ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_98890_2 1385935.N836_33990 8.96e-18 83.2 COG3108@1|root,COG3108@2|Bacteria,1GQNJ@1117|Cyanobacteria,1H8ID@1150|Oscillatoriales 1117|Cyanobacteria S Peptidase M15 - - - - - - - - - - - - Peptidase_M15_3 k59_16503_2 933262.AXAM01000111_gene2439 2.46e-44 154.0 COG1192@1|root,COG1192@2|Bacteria,1RFUN@1224|Proteobacteria,42RTS@68525|delta/epsilon subdivisions,2WNDF@28221|Deltaproteobacteria,2MJSU@213118|Desulfobacterales 28221|Deltaproteobacteria D 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family - - - - - - - - - - - - AAA_31 k59_198850_1 351016.RAZWK3B_16805 1.25e-32 128.0 2C2XN@1|root,32GT6@2|Bacteria,1REZE@1224|Proteobacteria,2U8HW@28211|Alphaproteobacteria 28211|Alphaproteobacteria S PFAM ERF family protein - - - - - - - - - - - - ERF k59_198850_3 319224.Sputcn32_0640 5.72e-35 127.0 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria,2Q8X8@267890|Shewanellaceae 1236|Gammaproteobacteria L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363,GO:1901576 - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_90031_1 1089439.KB902270_gene2574 2.46e-08 60.5 COG4379@1|root,COG4379@2|Bacteria,1MX68@1224|Proteobacteria 1224|Proteobacteria S Tail protein gpP - - - - - - - - - - - Phage_GPD k59_90042_3 1477404.A0A023NGM3_9CAUD 6.84e-13 68.2 4QBMV@10239|Viruses,4QUU6@35237|dsDNA viruses no RNA stage,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_107682_1 1556290.A0A0A0RL96_9CAUD 6.82e-110 339.0 4QGMJ@10239|Viruses,4QSYG@28883|Caudovirales,4QM5B@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_90044_1 1574422.A0A0A1ENW9_9CIRC 4.53e-38 140.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_265102_1 1618248.A0A0C5IB82_9CIRC 3.51e-31 124.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_99179_1 1234888.K0A2J2_9VIRU 4.37e-100 311.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_182769_1 1193128.A200_01691 1.63e-26 114.0 COG0305@1|root,COG0305@2|Bacteria,2GKXQ@201174|Actinobacteria,4CYY3@85004|Bifidobacteriales 201174|Actinobacteria L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_133083_1 1420600.W5RNT1_9CIRC 2.48e-22 99.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_75006_1 1692255.A0A0K1RL52_9CIRC 1.39e-10 67.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_352_2 1453501.JELR01000001_gene2535 7.8e-76 229.0 COG3772@1|root,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,1S6BA@1236|Gammaproteobacteria,46DFQ@72275|Alteromonadaceae 1236|Gammaproteobacteria G Phage lysozyme ybcS GO:0001906,GO:0001907,GO:0003674,GO:0003796,GO:0003824,GO:0004553,GO:0008150,GO:0016032,GO:0016787,GO:0016798,GO:0019048,GO:0019058,GO:0019076,GO:0031640,GO:0035821,GO:0035890,GO:0035891,GO:0039633,GO:0040011,GO:0044003,GO:0044004,GO:0044364,GO:0044403,GO:0044419,GO:0044659,GO:0044661,GO:0051701,GO:0051704,GO:0051817,GO:0051818,GO:0051883,GO:0052126,GO:0052192,GO:0061783 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_166134_3 2340.JV46_20980 1.19e-49 162.0 COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,1S3YC@1236|Gammaproteobacteria,1J5Z7@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_H k59_191039_1 1618238.A0A0C5I2G8_9CIRC 2.03e-35 132.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_149549_3 1121382.JQKG01000014_gene268 1.06e-15 82.8 COG4675@1|root,COG4675@2|Bacteria 2|Bacteria M tail collar domain protein - - - - - - - - - - - - Collar k59_108173_1 562981.HMPREF0428_01809 3.52e-12 79.3 2B4R5@1|root,31XHG@2|Bacteria,1UVXG@1239|Firmicutes,4I2CP@91061|Bacilli,3WFUD@539002|Bacillales incertae sedis 91061|Bacilli - - - - - - - - - - - - - - - k59_232558_27 1401297.U3PFP4_9CAUD 3.86e-20 104.0 4QBMV@10239|Viruses,4QUU6@35237|dsDNA viruses no RNA stage,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_232558_31 1458716.W8FWT5_9CAUD 1.93e-17 89.4 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_191041_3 1452718.JBOY01000021_gene715 1.06e-11 65.5 COG0553@1|root,COG0553@2|Bacteria 2|Bacteria L helicase activity - - - - - - - - - - - - Helicase_C,SNF2_N k59_50050_65 573569.F7308_1045 5.15e-09 64.7 COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,1RNHY@1236|Gammaproteobacteria,45ZTV@72273|Thiotrichales 72273|Thiotrichales O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ - - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG k59_50050_69 1610832.A0A0E3M1E6_9CAUD 3.58e-15 77.4 4QAIU@10239|Viruses,4QPDE@28883|Caudovirales 28883|Caudovirales S HNH endonuclease - - - - - - - - - - - - - k59_224746_1 563192.HMPREF0179_01974 2.42e-36 138.0 COG0553@1|root,COG0553@2|Bacteria,1NII1@1224|Proteobacteria 1224|Proteobacteria L SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,SNF2_N k59_216604_1 1692244.A0A0K1RLR5_9CIRC 4.99e-08 55.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_108647_1 440250.A5HL29_9CAUD 6.31e-26 101.0 4QAIK@10239|Viruses,4QUPH@35237|dsDNA viruses no RNA stage,4QPEB@28883|Caudovirales,4QNC3@10744|Podoviridae 10744|Podoviridae S endonuclease activity - - - - - - - - - - - - - k59_133590_1 1548905.A0A0A1IUN0_9CAUD 9.07e-14 72.8 4QB07@10239|Viruses,4QPGS@28883|Caudovirales,4QMBY@10699|Siphoviridae 10699|Siphoviridae S Domain of unknown function (DUF4326) - - - - - - - - - - - - - k59_199792_4 1051006.HMPREF1162_1154 5.37e-24 107.0 2F0SM@1|root,33TUQ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Rep_trans k59_58848_4 105154.Q9MBU0_9VIRU 6.94e-65 213.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_67170_1 293826.Amet_0541 1.6e-07 59.3 COG1388@1|root,COG3409@1|root,COG1388@2|Bacteria,COG3409@2|Bacteria,1V10C@1239|Firmicutes 1239|Firmicutes M PFAM LysM domain - - - - - - - - - - - - LysM k59_258098_3 1788439.A0A190WHD0_9CIRC 1.16e-29 121.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_42354_4 768710.DesyoDRAFT_5152 6.01e-06 53.1 2DT4K@1|root,33INK@2|Bacteria,1VQEE@1239|Firmicutes,253M4@186801|Clostridia 1239|Firmicutes - - - - - - - - - - - - - - - k59_999_2 1986029.Q9MBM7_9VIRU 2.3e-15 77.8 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_258175_1 1609634.A0A0C5AFV4_9VIRU 5.26e-24 100.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_258175_3 1165094.RINTHH_3920 8.82e-83 259.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_166840_1 2342.SOPEG_0824 2.55e-09 58.5 COG2974@1|root,COG2974@2|Bacteria,1MXPR@1224|Proteobacteria,1RMNN@1236|Gammaproteobacteria 1236|Gammaproteobacteria L May be involved in recombination rdgC GO:0000018,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009295,GO:0019219,GO:0019222,GO:0031323,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363 - ko:K03554 - - - - ko00000,ko03400 - - - RdgC k59_241364_1 417280.A1YZY2_9CAUD 1.69e-13 77.0 4QCZC@10239|Viruses,4QX3V@35237|dsDNA viruses no RNA stage,4QRH3@28883|Caudovirales,4QHVR@10662|Myoviridae 10662|Myoviridae S Bacterial DNA polymerase III alpha subunit - - - - - - - - - - - - - k59_208060_2 1236689.MMALV_07150 2.33e-07 60.8 COG0258@1|root,arCOG04050@2157|Archaea 1236689.MMALV_07150|- L Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into - - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - - k59_50715_1 1385658.U5KPZ6_9VIRU 4.85e-73 239.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_42426_1 1156919.QWC_12548 3.45e-53 184.0 2CK1H@1|root,33WMM@2|Bacteria,1RF5H@1224|Proteobacteria 1224|Proteobacteria S Protein of unknown function (DUF4043) - - - - - - - - - - - - DUF4043 k59_241365_1 1437882.AZRU01000111_gene4954 3.69e-30 120.0 28HHC@1|root,2Z7T2@2|Bacteria,1PZ57@1224|Proteobacteria,1SRT1@1236|Gammaproteobacteria 1236|Gammaproteobacteria S AAA domain - - - - - - - - - - - - AAA_24 k59_75624_1 1492922.GY26_16080 2.55e-38 142.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,1RP8Z@1236|Gammaproteobacteria,1J8Y8@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_75624_2 720554.Clocl_3718 2.43e-56 199.0 COG4695@1|root,COG4695@2|Bacteria,1TP8B@1239|Firmicutes,2497C@186801|Clostridia,3WHWY@541000|Ruminococcaceae 186801|Clostridia S Phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_9584_2 292414.TM1040_1655 1.07e-30 124.0 COG3391@1|root,COG3391@2|Bacteria 2|Bacteria CO amine dehydrogenase activity - - - ko:K12287 - - - - ko00000,ko02044 - - - DUF11,VCBS k59_225631_3 754027.HMPREF9554_00510 9.59e-11 66.2 COG5283@1|root,COG5283@2|Bacteria,2JAQ2@203691|Spirochaetes 203691|Spirochaetes S Phage tail tape measure protein, TP901 family - - - - - - - - - - - - PhageMin_Tail k59_200495_1 439235.Dalk_4556 6.94e-42 153.0 28MVD@1|root,2ZB2Y@2|Bacteria,1R8NK@1224|Proteobacteria,42QIP@68525|delta/epsilon subdivisions,2WKTY@28221|Deltaproteobacteria,2MME2@213118|Desulfobacterales 28221|Deltaproteobacteria S Protein of unknown function (DUF4043) - - - - - - - - - - - - DUF4043 k59_208668_1 935848.JAEN01000007_gene2923 5.79e-39 146.0 COG5323@1|root,COG5323@2|Bacteria,1MW8S@1224|Proteobacteria,2TREI@28211|Alphaproteobacteria,2PUVK@265|Paracoccus 28211|Alphaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_167559_1 292414.TM1040_0784 5.79e-62 198.0 2C2XN@1|root,32GT6@2|Bacteria,1REZE@1224|Proteobacteria,2U8HW@28211|Alphaproteobacteria 28211|Alphaproteobacteria S PFAM ERF family protein - - - - - - - - - - - - ERF k59_233471_2 1201035.KE007212_gene1417 6.01e-42 163.0 2CC8M@1|root,308VJ@2|Bacteria,1R789@1224|Proteobacteria,2U2NB@28211|Alphaproteobacteria,48TVI@772|Bartonellaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_191988_2 1395516.PMO01_05160 5.93e-89 274.0 COG2404@1|root,COG2404@2|Bacteria,1MXEH@1224|Proteobacteria,1SADM@1236|Gammaproteobacteria 1236|Gammaproteobacteria S phosphoesterase DHHA1 - - - - - - - - - - - - DHHA1 k59_191988_4 1027273.GZ77_09015 5.33e-60 196.0 28HHC@1|root,2Z7T2@2|Bacteria,1PZ57@1224|Proteobacteria,1SRT1@1236|Gammaproteobacteria 1236|Gammaproteobacteria S AAA domain - - - - - - - - - - - - AAA_24 k59_258926_1 1238186.AOCN01000026_gene2066 1.61e-13 75.5 COG0739@1|root,COG0739@2|Bacteria,2GXEC@201174|Actinobacteria,4FPUU@85023|Microbacteriaceae 201174|Actinobacteria M Peptidase family M23 nlpD - - - - - - - - - - - Peptidase_M23 k59_117927_1 1379725.S5SYG4_9CIRC 1.66e-29 118.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_43188_2 658172.CKC_05955 8.47e-20 90.5 COG0749@1|root,COG0749@2|Bacteria,1MWX7@1224|Proteobacteria,2UNT9@28211|Alphaproteobacteria,4BJFM@82115|Rhizobiaceae 28211|Alphaproteobacteria L COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A,DNA_pol_A_exo1 k59_92775_1 1129374.AJE_04971 8.26e-181 515.0 COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,1RMJ1@1236|Gammaproteobacteria,465SY@72275|Alteromonadaceae 1236|Gammaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_3,Phage_int_SAM_3,Phage_integrase k59_92775_4 231434.JQJH01000030_gene1407 1.62e-24 99.0 COG1974@1|root,COG1974@2|Bacteria,1MZFA@1224|Proteobacteria,2UCXW@28211|Alphaproteobacteria 28211|Alphaproteobacteria KT Belongs to the peptidase S24 family umuD - - ko:K03503 - - - - ko00000,ko01000,ko01002,ko03400 - - - Peptidase_S24 k59_92775_6 658187.LDG_5994 4.75e-175 511.0 COG3378@1|root,COG3378@2|Bacteria,1R6CB@1224|Proteobacteria,1S35E@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage plasmid primase P4 family - - - - - - - - - - - - - k59_84359_2 61273.S3BW10 1.65e-05 53.9 COG0465@1|root,KOG0743@2759|Eukaryota,39U06@33154|Opisthokonta,3NX6C@4751|Fungi,3QMIC@4890|Ascomycota,214AG@147550|Sordariomycetes,3UPY0@5151|Ophiostomatales 4751|Fungi U BCS1_N - - - ko:K08900 - - - - ko00000,ko03029 - - - AAA,BCS1_N k59_126197_6 1234888.K0A2J2_9VIRU 5.26e-46 164.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_43750_2 105154.Q9MBU0_9VIRU 6.79e-19 86.7 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_168412_2 466088.CL42_01225 3.38e-16 80.5 COG0210@1|root,COG0210@2|Bacteria,1R4PV@1224|Proteobacteria,1RZXT@1236|Gammaproteobacteria,3NJ6N@468|Moraxellaceae 1236|Gammaproteobacteria L DNA helicase - - - - - - - - - - - - AAA_19,UvrD-helicase,UvrD_C,UvrD_C_2 k59_43752_1 762982.HMPREF9442_01223 1.58e-08 61.2 COG0270@1|root,COG0270@2|Bacteria,4NJPP@976|Bacteroidetes,2FKYT@200643|Bacteroidia 976|Bacteroidetes H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_93324_1 1536597.A0A088F6J4_9CAUD 1.37e-32 128.0 4QAIK@10239|Viruses,4QPEB@28883|Caudovirales,4QP3P@10744|Podoviridae 10744|Podoviridae S phosphoprotein phosphatase activity - - - - - - - - - - - - - k59_226362_2 314282.PCNPT3_11640 5.93e-22 95.1 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria,2QHMK@267894|Psychromonadaceae 1236|Gammaproteobacteria L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363,GO:1901576 - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_209297_1 1296660.S5MUB5_9CAUD 4.14e-16 79.3 4QC5D@10239|Viruses,4QVY9@35237|dsDNA viruses no RNA stage,4QPVU@28883|Caudovirales,4QIJW@10662|Myoviridae 10662|Myoviridae S Protein of unknown function (DUF2800) - - - - - - - - - - - - - k59_209297_2 1111131.HMPREF1255_1442 6.98e-64 201.0 28J2E@1|root,2Z8YX@2|Bacteria,2IB5J@201174|Actinobacteria 201174|Actinobacteria S Protein of unknown function (DUF2815) - - - - - - - - - - - - DUF2815 k59_209297_3 1567012.A0A0A7RTL3_9VIRU 1.19e-235 675.0 4QAKM@10239|Viruses 10239|Viruses S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_209297_5 439292.Bsel_3022 8.59e-58 202.0 COG5545@1|root,COG5545@2|Bacteria,1TQNX@1239|Firmicutes,4HCHZ@91061|Bacilli 91061|Bacilli T Virulence-associated protein E - - - - - - - - - - - - VirE k59_259755_1 1122247.C731_2954 1.54e-49 178.0 COG0209@1|root,COG0209@2|Bacteria,2IC1H@201174|Actinobacteria,23CT3@1762|Mycobacteriaceae 201174|Actinobacteria F Ribonucleotide reductase, barrel domain - - - - - - - - - - - - Ribonuc_red_lgC k59_27572_1 1692244.A0A0K1RLR5_9CIRC 1.41e-20 92.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_27572_3 1120979.ATVB01000007_gene1117 8.13e-10 63.2 28MKK@1|root,2ZAWR@2|Bacteria,2IS2W@201174|Actinobacteria,4D1DD@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - RNA_helicase,Viral_Rep k59_52344_3 765912.Thimo_1718 1.45e-42 141.0 COG3093@1|root,COG3093@2|Bacteria,1N76J@1224|Proteobacteria,1SCYV@1236|Gammaproteobacteria,1WYTT@135613|Chromatiales 135613|Chromatiales K TIGRFAM Addiction module antidote protein, HigA - - - ko:K21498 - - - - ko00000,ko02048 - - - HTH_3 k59_168539_1 1327970.R9ZXU8_9CAUD 2.98e-06 50.1 4QFZ4@10239|Viruses,4QWCA@35237|dsDNA viruses no RNA stage,4QPIG@28883|Caudovirales,4QMKQ@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_168539_2 1121926.AXWO01000016_gene4138 1.02e-06 59.7 COG1674@1|root,COG1674@2|Bacteria,2GK3T@201174|Actinobacteria,4EXQP@85014|Glycomycetales 201174|Actinobacteria D Ftsk_gamma ftsK GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma k59_10378_1 1121324.CLIT_13c01770 0.000155 46.6 COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,247TQ@186801|Clostridia,25R2J@186804|Peptostreptococcaceae 186801|Clostridia L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC - - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N k59_43909_1 1618248.A0A0C5IB82_9CIRC 5.41e-15 80.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_84821_1 78245.Xaut_3704 6.72e-67 217.0 COG5323@1|root,COG5323@2|Bacteria,1MW8S@1224|Proteobacteria,2TREI@28211|Alphaproteobacteria,3EYR8@335928|Xanthobacteraceae 28211|Alphaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_27575_1 349521.HCH_00790 3.35e-11 65.1 COG2404@1|root,COG2404@2|Bacteria,1MXEH@1224|Proteobacteria,1SADM@1236|Gammaproteobacteria 1236|Gammaproteobacteria S phosphoesterase DHHA1 - - - - - - - - - - - - DHHA1 k59_177025_1 630626.EBL_c21750 2.09e-33 129.0 28J9D@1|root,2Z94E@2|Bacteria,1QE0C@1224|Proteobacteria,1RZ22@1236|Gammaproteobacteria 1236|Gammaproteobacteria S P22 coat protein - gene protein 5 - - - - - - - - - - - - P22_CoatProtein k59_144514_1 195105.CN97_00640 1.66e-41 147.0 COG3772@1|root,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,2U7X4@28211|Alphaproteobacteria 28211|Alphaproteobacteria G lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_36035_1 746697.Aeqsu_1032 0.000724 51.2 COG3391@1|root,COG5492@1|root,COG3391@2|Bacteria,COG5492@2|Bacteria,4NH7Q@976|Bacteroidetes,1HXMH@117743|Flavobacteriia 976|Bacteroidetes N domain, Protein - - - - - - - - - - - - - k59_36035_2 926556.Echvi_4543 6.8e-15 84.3 COG2911@1|root,COG2911@2|Bacteria,4NHHA@976|Bacteroidetes,47XBI@768503|Cytophagia 976|Bacteroidetes M Calx-beta domain - - - ko:K20276 ko02024,map02024 - - - ko00000,ko00001 - - - Big_4,CHU_C,Calx-beta,He_PIG,NHL,TIG,fn3 k59_234611_1 2003327.CAPSD_BPCHP 2.49e-11 69.7 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_127934_1 1357714.A0A067XQQ4_9CAUD 7.98e-17 82.4 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QHVQ@10662|Myoviridae 10662|Myoviridae S nucleotide binding - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016032,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019058,GO:0019079,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0039686,GO:0039693,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044403,GO:0044419,GO:0046483,GO:0051704,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_53134_4 1193181.BN10_1230014 3.57e-08 65.1 COG1674@1|root,COG1716@1|root,COG1674@2|Bacteria,COG1716@2|Bacteria,2GJBR@201174|Actinobacteria,4FF4U@85021|Intrasporangiaceae 201174|Actinobacteria D FtsK/SpoIIIE family - - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_SpoIIIE,Yop-YscD_cpl k59_209890_3 1589751.A0A0C5AEN1_9CAUD 1.81e-12 72.8 4QBNM@10239|Viruses,4QPUI@28883|Caudovirales,4QKV6@10699|Siphoviridae 10699|Siphoviridae S Clp protease - - - - - - - - - - - - - k59_44620_6 1234888.K0A2J2_9VIRU 7.57e-145 431.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_36062_1 497964.CfE428DRAFT_1361 1.26e-26 117.0 COG5283@1|root,COG5283@2|Bacteria,46VP2@74201|Verrucomicrobia 74201|Verrucomicrobia - - - - - - - - - - - - - - - k59_135940_1 428125.CLOLEP_01377 4.63e-44 149.0 2E0G5@1|root,32W28@2|Bacteria,1VAS0@1239|Firmicutes,24NYA@186801|Clostridia,3WNKT@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_135940_2 691965.D4P7I3_9CAUD 2.26e-76 258.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_28417_1 1416009.V9VG35_9CAUD 2.17e-17 82.8 4QDXM@10239|Viruses,4QWIX@35237|dsDNA viruses no RNA stage,4QQF6@28883|Caudovirales,4QNXH@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_85293_1 1121459.AQXE01000015_gene277 4.64e-07 57.4 COG5434@1|root,COG5434@2|Bacteria,1PGI5@1224|Proteobacteria,435Q3@68525|delta/epsilon subdivisions,2X046@28221|Deltaproteobacteria,2MAEU@213115|Desulfovibrionales 28221|Deltaproteobacteria M Belongs to the glycosyl hydrolase 28 family - - - - - - - - - - - - - k59_227122_1 105154.Q9MBU6_9VIRU 9.01e-111 341.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_193271_4 1327977.S0A0N2_9CAUD 5.31e-31 126.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales 28883|Caudovirales S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_44628_2 156889.Mmc1_1722 1.06e-11 70.5 COG4675@1|root,COG4675@2|Bacteria,1Q34D@1224|Proteobacteria,2UJKF@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Membrane - - - - - - - - - - - - - k59_185423_1 269482.Bcep1808_1184 2.98e-70 238.0 COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,2VKFN@28216|Betaproteobacteria,1K0GR@119060|Burkholderiaceae 28216|Betaproteobacteria M transglycosylase slt - - ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 - DUF4124,SLT k59_10966_2 1280682.AUKA01000008_gene3173 0.000281 48.5 COG3864@1|root,COG3864@2|Bacteria,1TQ6J@1239|Firmicutes,24C34@186801|Clostridia,4BY92@830|Butyrivibrio 186801|Clostridia S Putative metallopeptidase domain - - - - - - - - - - - - DUF2201,DUF2201_N k59_19710_6 105154.Q9MBU6_9VIRU 2.17e-136 414.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_145436_1 652103.Rpdx1_2955 1.74e-49 169.0 28PTM@1|root,2ZCEU@2|Bacteria,1R5DD@1224|Proteobacteria,2TVG7@28211|Alphaproteobacteria,3JU4C@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Family of unknown function (DUF5309) - - - - - - - - - - - - DUF5309 k59_4483_2 1347392.CCEZ01000011_gene2447 1.56e-15 85.5 COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,36DTR@31979|Clostridiaceae 186801|Clostridia L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_227808_1 1479238.JQMZ01000001_gene2181 2.2e-14 77.8 COG5511@1|root,COG5511@2|Bacteria,1MVN4@1224|Proteobacteria,2TSGI@28211|Alphaproteobacteria 28211|Alphaproteobacteria OU Phage portal protein lambda family - - - - - - - - - - - - Phage_portal_2 k59_170005_2 1379722.S5SY31_9CIRC 7.45e-102 304.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_227809_1 1609634.A0A0C5AFT2_9VIRU 5.27e-25 106.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_78508_1 935261.JAGL01000009_gene1165 4.36e-76 248.0 COG0209@1|root,COG0209@2|Bacteria,1PM78@1224|Proteobacteria,2UZUM@28211|Alphaproteobacteria,43QGW@69277|Phyllobacteriaceae 28211|Alphaproteobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides - - - - - - - - - - - - - k59_19799_1 391615.ABSJ01000042_gene2222 8.93e-28 112.0 COG2974@1|root,COG2974@2|Bacteria,1MXPR@1224|Proteobacteria,1RMNN@1236|Gammaproteobacteria,1J58F@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L May be involved in recombination rdgC GO:0000018,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009295,GO:0019219,GO:0019222,GO:0031323,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363 - ko:K03554 - - - - ko00000,ko03400 - - - RdgC k59_19799_3 580332.Slit_1940 4.71e-12 62.8 COG4197@1|root,COG4197@2|Bacteria,1NHMT@1224|Proteobacteria,2VXKP@28216|Betaproteobacteria 28216|Betaproteobacteria S Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT - - - - - - - - - - - - YdaS_antitoxin k59_36709_2 502025.Hoch_0774 1.58e-09 62.8 2AA2P@1|root,30ZBD@2|Bacteria,1PM8Z@1224|Proteobacteria,434GH@68525|delta/epsilon subdivisions,2WYTW@28221|Deltaproteobacteria,2Z0KT@29|Myxococcales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_153460_17 266834.SMc04187 2.48e-70 239.0 COG5565@1|root,COG5565@2|Bacteria,1R6R3@1224|Proteobacteria,2U1P9@28211|Alphaproteobacteria,4BDQ9@82115|Rhizobiaceae 28211|Alphaproteobacteria S DNA packaging protein gp2 - - - - - - - - - - - - Terminase_6,Terminase_6C k59_20582_1 1692252.A0A0K1RL35_9CIRC 2.46e-41 145.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_178832_1 1051985.l11_02320 3.79e-08 61.6 COG0863@1|root,COG0863@2|Bacteria,1MY4G@1224|Proteobacteria,2VQD7@28216|Betaproteobacteria,2KT8D@206351|Neisseriales 206351|Neisseriales H DNA methylase - - 2.1.1.113 ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_236016_2 1220601.L7TJ79_9CAUD 2.63e-79 256.0 4QCM5@10239|Viruses,4QVZY@35237|dsDNA viruses no RNA stage,4QQFH@28883|Caudovirales 28883|Caudovirales S Bacteriophage head to tail connecting protein - GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019028,GO:0019058,GO:0019068,GO:0019072,GO:0019073,GO:0032991,GO:0044403,GO:0044419,GO:0044423,GO:0046798,GO:0051704 - - - - - - - - - - - k59_228780_1 1120936.KB907208_gene1107 1.24e-87 280.0 COG0209@1|root,COG0209@2|Bacteria,2IC1H@201174|Actinobacteria 201174|Actinobacteria F Ribonucleotide reductase, barrel domain - - - - - - - - - - - - Ribonuc_red_lgC k59_154503_1 1556290.A0A0A0RM00_9CAUD 7.08e-76 246.0 4QAXQ@10239|Viruses,4QRFY@28883|Caudovirales,4QM52@10699|Siphoviridae 10699|Siphoviridae S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor - - - - - - - - - - - - - k59_79302_1 1122201.AUAZ01000021_gene3157 5.21e-16 83.6 2EXSU@1|root,33R23@2|Bacteria,1NS77@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_5588_5 1125973.JNLC01000012_gene891 2.58e-07 57.0 2C1TB@1|root,2ZB27@2|Bacteria,1N020@1224|Proteobacteria,2UP9F@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_171174_3 1636271.A0A0E3M3Z1_9CAUD 1.04e-19 88.2 4QAIK@10239|Viruses,4QPEB@28883|Caudovirales,4QKNC@10699|Siphoviridae 10699|Siphoviridae S hydrolase activity - - - - - - - - - - - - - k59_194962_1 1618259.A0A0C5I2B5_9CIRC 1.91e-42 147.0 4QE84@10239|Viruses,4QUKR@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_236149_1 1609634.A0A0C5AFV4_9VIRU 6.92e-62 207.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_129879_6 986075.CathTA2_0677 1.85e-13 74.7 COG0741@1|root,COG4942@1|root,COG0741@2|Bacteria,COG4942@2|Bacteria,1V8NJ@1239|Firmicutes,4HKSS@91061|Bacilli 91061|Bacilli D Transglycosylase SLT domain - - - - - - - - - - - - Peptidase_M23,SLT_2 k59_95464_2 438753.AZC_3585 1.04e-90 281.0 28IR7@1|root,2Z8QR@2|Bacteria,1PBTP@1224|Proteobacteria,2U248@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_104137_2 930169.B5T_02085 1.25e-20 85.9 2E3RU@1|root,32YPG@2|Bacteria,1NAWV@1224|Proteobacteria,1SDMM@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_162809_4 1238190.AMQY01000021_gene1593 2.53e-14 79.7 COG0749@1|root,COG0749@2|Bacteria,1MWX7@1224|Proteobacteria,1S0Q1@1236|Gammaproteobacteria 1236|Gammaproteobacteria L ORF located using Glimmer RBSfinder - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A,DNA_pol_A_exo1 k59_171936_1 105154.Q9MBU6_9VIRU 7.5e-79 252.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_138687_1 392499.Swit_1578 4.14e-07 59.7 COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,1MVH7@1224|Proteobacteria,2TRNA@28211|Alphaproteobacteria,2K05E@204457|Sphingomonadales 204457|Sphingomonadales KL DNA methylase - - - - - - - - - - - - N6_N4_Mtase,ParBc k59_87377_2 283699.D172_2689 5.56e-12 65.9 2E645@1|root,330T3@2|Bacteria,1NEGX@1224|Proteobacteria,1SC3K@1236|Gammaproteobacteria,2Q4P5@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S Holin of 3TMs, for gene-transfer release - - - - - - - - - - - - GTA_holin_3TM k59_87377_5 450851.PHZ_c0719 4.07e-12 69.3 COG0739@1|root,COG0739@2|Bacteria,1NQ1V@1224|Proteobacteria,2URCJ@28211|Alphaproteobacteria,2KIJ2@204458|Caulobacterales 204458|Caulobacterales M Peptidase family M23 - - - - - - - - - - - - Peptidase_M23 k59_138693_2 742725.HMPREF9450_02123 7.62e-37 140.0 COG1196@1|root,COG1196@2|Bacteria,4NMBI@976|Bacteroidetes,2FR6N@200643|Bacteroidia 976|Bacteroidetes D nuclear chromosome segregation - - - - - - - - - - - - - k59_262770_6 172045.KS04_01335 9.82e-05 51.2 2EI2J@1|root,33BTZ@2|Bacteria,4NZI5@976|Bacteroidetes,1I6DF@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_262770_9 1265310.CCBD010000081_gene5127 8.22e-06 56.6 COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,2IBWG@201174|Actinobacteria,236HX@1762|Mycobacteriaceae 201174|Actinobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_tranf_2_3,Glycos_transf_1 k59_188298_2 1692250.A0A0K1RLR1_9CIRC 8e-21 90.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_179654_1 1502724.FF80_03299 3.66e-75 233.0 COG0175@1|root,COG0175@2|Bacteria 2|Bacteria EH sulfate reduction - - - - - - - - - - - - PAPS_reduct k59_195626_1 1609634.A0A0C5AFT2_9VIRU 9.82e-58 194.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_47674_2 1144310.PMI07_002360 1.76e-05 55.5 2DPZ1@1|root,3340X@2|Bacteria,1R2EE@1224|Proteobacteria,2TZIB@28211|Alphaproteobacteria,4BP2Q@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_38136_1 536232.CLM_2667 2.6e-92 286.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,36DK9@31979|Clostridiaceae 186801|Clostridia L snf2 family - - - - - - - - - - - - Helicase_C,SNF2_N k59_7541_2 1458848.X2KS68_9CAUD 3.06e-51 174.0 4QGGR@10239|Viruses,4QZHR@35237|dsDNA viruses no RNA stage,4QUGZ@28883|Caudovirales,4QNY3@10744|Podoviridae 10744|Podoviridae S viral capsid - - - - - - - - - - - - - k59_223451_1 1692246.A0A0K1RL26_9CIRC 2.72e-16 85.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_148486_1 2003327.CAPSD_BPCHP 8.53e-30 121.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_148486_5 1609634.A0A0C5ANA6_9VIRU 1.37e-05 53.1 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_148486_6 2003327.CAPSD_BPCHP 1.66e-92 296.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_105753_2 742733.HMPREF9469_05062 1.65e-128 382.0 COG0553@1|root,COG0553@2|Bacteria,1TS9W@1239|Firmicutes,24CGX@186801|Clostridia,222GT@1506553|Lachnoclostridium 186801|Clostridia KL Helicase conserved C-terminal domain - - - - - - - - - - - - - k59_105753_3 742733.HMPREF9469_05065 2.21e-37 133.0 2E0G5@1|root,324TP@2|Bacteria,1UQZN@1239|Firmicutes,258ST@186801|Clostridia,222Q1@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_105753_4 691965.D4P7I3_9CAUD 6.81e-179 543.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_7689_1 212035.YL364_MIMIV 3.6e-37 149.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage 10239|Viruses S N-methyltransferase activity - GO:0005575,GO:0019012 - - - - - - - - - - - k59_148609_3 1227352.C173_13411 8.42e-15 80.9 COG0366@1|root,COG2819@1|root,COG4733@1|root,COG0366@2|Bacteria,COG2819@2|Bacteria,COG4733@2|Bacteria,1TXXX@1239|Firmicutes,4I70R@91061|Bacilli,26VRX@186822|Paenibacillaceae 91061|Bacilli G Starch binding domain - - - - - - - - - - - - CBM_25 k59_139807_3 1618260.A0A0C5I2C5_9CIRC 8.06e-57 190.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_230465_3 1367847.JCM7686_pAMI4p331 2.2e-08 64.3 COG1573@1|root,COG1573@2|Bacteria,1MW8T@1224|Proteobacteria,2TSAR@28211|Alphaproteobacteria,2PU9U@265|Paracoccus 28211|Alphaproteobacteria L Domain of unknown function (DUF4130 dpoL - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - DUF4130,UDG k59_205969_1 1618237.A0A0C5IMG6_9CIRC 2.34e-17 85.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_131508_1 1206545.S6CGI5_9CAUD 1.11e-135 417.0 4QBG0@10239|Viruses,4QWYZ@35237|dsDNA viruses no RNA stage,4QSGM@28883|Caudovirales,4QK1H@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_131508_2 1211643.K4JSN2_9CAUD 1.54e-09 60.1 4QFW3@10239|Viruses,4R0GR@35237|dsDNA viruses no RNA stage,4QS8R@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_131508_4 945550.VISI1226_13331 1.42e-25 112.0 COG1226@1|root,COG1226@2|Bacteria,1NT9G@1224|Proteobacteria,1RZME@1236|Gammaproteobacteria,1XTBJ@135623|Vibrionales 135623|Vibrionales P COG1226 Kef-type K transport systems VP1064 - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans_2,TrkA_N k59_131508_6 52598.EE36_15732 2.55e-121 364.0 COG0754@1|root,COG0754@2|Bacteria,1MW6V@1224|Proteobacteria,2TU8J@28211|Alphaproteobacteria,3ZWRY@60136|Sulfitobacter 28211|Alphaproteobacteria E Glutathionylspermidine synthase preATP-grasp MA20_09650 - - - - - - - - - - - GSP_synth k59_131508_7 232346.JHQL01000006_gene2995 2.59e-05 51.2 COG5463@1|root,COG5463@2|Bacteria 2|Bacteria S Protein of unknown function (DUF1190) yjfM - - - - - - - - - - - DUF1190 k59_88002_1 1121937.AUHJ01000007_gene1934 1.79e-63 199.0 2DICG@1|root,302RI@2|Bacteria,1PVSB@1224|Proteobacteria,1STCY@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_115753_1 2003327.CAPSD_BPCHP 1.78e-27 116.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_115753_2 1234888.K0A2R8_9VIRU 4.94e-45 159.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_254995_1 105154.Q9MBU0_9VIRU 2.84e-50 174.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_254995_3 1385658.U5KPZ6_9VIRU 3.26e-31 121.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_264366_1 717606.PaecuDRAFT_4465 4.66e-10 67.0 COG2730@1|root,COG3209@1|root,COG2730@2|Bacteria,COG3209@2|Bacteria 2|Bacteria M self proteolysis - - 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 - R06200,R11307,R11308 - ko00000,ko00001,ko01000 - GH5,GH9 - Cellulase,Cytochrom_C,Dockerin_1,F5_F8_type_C,Glyco_hydro_43,RicinB_lectin_2,Ricin_B_lectin k59_131955_4 1537917.JU82_09980 2.66e-25 99.8 2ARVA@1|root,31H70@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - HK97-gp10_like k59_123901_1 857087.Metme_2336 3.12e-55 187.0 2CI0W@1|root,2Z81W@2|Bacteria,1R9FZ@1224|Proteobacteria,1S0NA@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage X family - - - - - - - - - - - - Phage_CRI,Phage_X k59_49645_1 1161935.H9D1H5_9CAUD 7.41e-26 107.0 4QCM5@10239|Viruses,4QVZY@35237|dsDNA viruses no RNA stage,4QQFH@28883|Caudovirales,4QNDH@10744|Podoviridae 10744|Podoviridae S Bacteriophage head to tail connecting protein - GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019028,GO:0019058,GO:0019068,GO:0019072,GO:0019073,GO:0032991,GO:0044403,GO:0044419,GO:0044423,GO:0046798,GO:0051704 - - - - - - - - - - - k59_124064_1 272943.RSP_3722 1.04e-44 158.0 COG2236@1|root,COG2236@2|Bacteria,1R7GH@1224|Proteobacteria,2U4UX@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Phosphoribosyl transferase domain - - - - - - - - - - - - Pribosyltran k59_164470_2 520999.PROVALCAL_01867 3.65e-33 119.0 COG3179@1|root,COG3179@2|Bacteria,1RE8K@1224|Proteobacteria,1S4U8@1236|Gammaproteobacteria,3Z9BP@586|Providencia 1236|Gammaproteobacteria S D-alanyl-D-alanine carboxypeptidase - - - - - - - - - - - - Peptidase_M15_4 k59_140521_1 290633.GOX2477 1.08e-56 194.0 2CHRY@1|root,30Z9E@2|Bacteria,1RGQK@1224|Proteobacteria,2U9J0@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - RecT k59_132078_1 1226325.HMPREF1548_02959 8.53e-10 57.4 COG1694@1|root,COG1694@2|Bacteria,1VIQA@1239|Firmicutes,24SKH@186801|Clostridia,36SG4@31979|Clostridiaceae 186801|Clostridia S MazG nucleotide pyrophosphohydrolase domain - - - - - - - - - - - - MazG k59_264510_1 1385658.U5KPZ6_9VIRU 2.69e-70 230.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_64131_1 1986029.Q9MBM8_9VIRU 5.31e-60 201.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_181389_1 1379722.S5SY31_9CIRC 2.53e-55 181.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_124075_1 1234888.K0A2J2_9VIRU 6.93e-89 276.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_64133_1 698486.D2XJ98_9CAUD 1.41e-20 93.6 4QVZ9@35237|dsDNA viruses no RNA stage,4QPXI@28883|Caudovirales 28883|Caudovirales S C-5 cytosine-specific DNA methylase - - - - - - - - - - - - - k59_140531_1 1493510.A0A0E3ICA9_9CAUD 9.31e-07 57.0 4QB69@10239|Viruses,4QSF0@28883|Caudovirales,4QJ3A@10662|Myoviridae 10662|Myoviridae S peptidase activity - - - - - - - - - - - - - k59_156812_2 888055.HMPREF9015_01067 8.94e-07 57.8 COG3935@1|root,COG3935@2|Bacteria,37ANW@32066|Fusobacteria 32066|Fusobacteria L Helix-turn-helix domain - - - - - - - - - - - - HTH_36 k59_156812_4 33035.JPJF01000071_gene4462 4.16e-21 94.4 28JXH@1|root,2ZA3Z@2|Bacteria,1V5C4@1239|Firmicutes,24J0M@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_165401_8 1358423.N180_02870 4.44e-08 57.4 2DEUM@1|root,2ZPBE@2|Bacteria,4P78P@976|Bacteroidetes,1IZYU@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_165401_9 1497679.EP56_02095 3.24e-09 59.7 2EGZP@1|root,33ART@2|Bacteria 2|Bacteria S YopX protein - - - - - - - - - - - - YopX k59_40693_1 691965.D4P7I3_9CAUD 1.87e-144 449.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_182205_2 693746.OBV_42570 4.98e-82 253.0 COG0175@1|root,COG0175@2|Bacteria,1UZK3@1239|Firmicutes,24CWM@186801|Clostridia,2N8BZ@216572|Oscillospiraceae 186801|Clostridia EH Psort location Cytoplasmic, score - - - - - - - - - - - - - k59_256193_2 1080067.BAZH01000011_gene686 8.23e-40 148.0 COG1783@1|root,COG1783@2|Bacteria,1RGDZ@1224|Proteobacteria 1224|Proteobacteria S phage Terminase large subunit - - - - - - - - - - - - - k59_40711_1 1385658.U5KPZ6_9VIRU 3.82e-37 141.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_74631_3 716928.AJQT01000109_gene1217 6.61e-44 147.0 2FEUE@1|root,346TC@2|Bacteria,1MZPB@1224|Proteobacteria,2UC4Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_264951_3 658172.CKC_03455 2.44e-24 113.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 658172.CKC_03455|- - - - - - - - - - - - - - - - k59_40896_1 1197951.I6RT34_9CAUD 4.39e-200 571.0 4QGAG@10239|Viruses,4R0KB@35237|dsDNA viruses no RNA stage,4QUA4@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_165610_1 488538.SAR116_0377 2.84e-55 188.0 COG4373@1|root,COG4373@2|Bacteria 2|Bacteria - - gp17a - - ko:K06909 - - - - ko00000 - - - Terminase_6,Terminase_6C k59_165610_2 488538.SAR116_0376 9.82e-48 177.0 COG3064@1|root,COG3064@2|Bacteria,1R6JV@1224|Proteobacteria,2U5NE@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Membrane - - - - - - - - - - - - - k59_190984_2 675817.VDA_000912 4.64e-05 47.4 COG4733@1|root,COG4733@2|Bacteria,1NCQ4@1224|Proteobacteria,1SEXE@1236|Gammaproteobacteria,1XZ43@135623|Vibrionales 135623|Vibrionales S Domain of unknown function (DUF1983) - - - - - - - - - - - - DUF1983 k59_116451_1 1609634.A0A0C5AFV4_9VIRU 6.08e-76 245.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_157814_1 1120970.AUBZ01000070_gene1594 2.14e-20 90.9 2CEG2@1|root,2ZCEX@2|Bacteria,1RB74@1224|Proteobacteria,1S2JC@1236|Gammaproteobacteria,46AFF@72275|Alteromonadaceae 1236|Gammaproteobacteria S Phage replication protein CRI - - - - - - - - - - - - Phage_CRI,Phage_X k59_157814_6 1122194.AUHU01000013_gene665 1.15e-106 325.0 COG4128@1|root,COG4128@2|Bacteria,1REHG@1224|Proteobacteria,1S491@1236|Gammaproteobacteria,46BRE@72275|Alteromonadaceae 1236|Gammaproteobacteria S Zonular occludens toxin (Zot) - - - - - - - - - - - - Zot k59_157814_10 1120970.AUBZ01000070_gene1594 2.24e-28 115.0 2CEG2@1|root,2ZCEX@2|Bacteria,1RB74@1224|Proteobacteria,1S2JC@1236|Gammaproteobacteria,46AFF@72275|Alteromonadaceae 1236|Gammaproteobacteria S Phage replication protein CRI - - - - - - - - - - - - Phage_CRI,Phage_X k59_33517_2 756277.A0A096VKZ4_9VIRU 6.12e-18 83.6 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage 10239|Viruses S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_99791_3 935261.JAGL01000009_gene1177 1.41e-61 221.0 COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1QT52@1224|Proteobacteria,2TVNI@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Toprim-like - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - DnaB_C,Toprim_2 k59_99791_6 698761.RTCIAT899_CH00990 2e-10 70.1 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2TRJF@28211|Alphaproteobacteria,4B86G@82115|Rhizobiaceae 28211|Alphaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_108139_2 665956.HMPREF1032_00674 1.71e-13 74.7 28J3N@1|root,2Z8ZU@2|Bacteria,1V15Z@1239|Firmicutes,249Z0@186801|Clostridia,3WNJZ@541000|Ruminococcaceae 186801|Clostridia S Phage portal protein - - - - - - - - - - - - Phage_portal k59_174241_2 608538.HTH_0543 5.14e-28 124.0 COG5362@1|root,COG5362@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Terminase_6C k59_149577_3 420324.KI911948_gene9096 2.5e-08 56.2 COG4695@1|root,COG4695@2|Bacteria 2|Bacteria N Portal protein - - - - - - - - - - - - Collagen k59_133104_2 742740.HMPREF9474_02299 2.02e-131 390.0 COG0553@1|root,COG0553@2|Bacteria,1TS9W@1239|Firmicutes,24CGX@186801|Clostridia,222GT@1506553|Lachnoclostridium 186801|Clostridia KL Helicase conserved C-terminal domain - - - - - - - - - - - - - k59_174290_1 1692249.A0A0K1RL40_9CIRC 1.57e-50 175.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_215992_4 2003327.REP_BPCHP 1.28e-21 101.0 4QCVK@10239|Viruses,4QUMV@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_33574_1 1234888.K0A2J2_9VIRU 1.61e-36 143.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_91599_1 891968.Anamo_0662 1.15e-25 111.0 COG0587@1|root,COG0587@2|Bacteria,3T9YG@508458|Synergistetes 508458|Synergistetes L DNA polymerase III alpha subunit dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP k59_8688_6 563192.HMPREF0179_02928 4.97e-26 100.0 COG4570@1|root,COG4570@2|Bacteria,1N92D@1224|Proteobacteria,431HK@68525|delta/epsilon subdivisions,2WWYH@28221|Deltaproteobacteria,2MFAB@213115|Desulfovibrionales 28221|Deltaproteobacteria L Endodeoxyribonuclease RusA - - - - - - - - - - - - RusA k59_124845_1 1035191.HMPREF0185_03555 2.84e-23 107.0 28I9J@1|root,2Z8C8@2|Bacteria,1NQUB@1224|Proteobacteria 1224|Proteobacteria S Bacteriophage replication gene A protein (GPA) - - - - - - - - - - - - Phage_GPA k59_199950_1 665942.HMPREF1022_03283 1.99e-51 176.0 28IR7@1|root,2Z8QR@2|Bacteria,1PBTP@1224|Proteobacteria,42Z7V@68525|delta/epsilon subdivisions,2WTZ3@28221|Deltaproteobacteria,2M8NA@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_183428_2 1828.JOKB01000010_gene5308 8.54e-21 84.7 2BQQI@1|root,32JM2@2|Bacteria,2GYV9@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_174872_4 1370122.JHXQ01000023_gene3058 2.48e-25 102.0 COG3023@1|root,COG3023@2|Bacteria,1N032@1224|Proteobacteria,2U6P9@28211|Alphaproteobacteria,4BHDN@82115|Rhizobiaceae 28211|Alphaproteobacteria V N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - Amidase_2,PG_binding_1 k59_216856_1 1078085.HMPREF1210_01174 4.05e-25 102.0 COG3723@1|root,COG3723@2|Bacteria,1V0QW@1239|Firmicutes,4HBS2@91061|Bacilli,26HGR@186818|Planococcaceae 91061|Bacilli L RecT family - - - ko:K07455 - - - - ko00000,ko03400 - - - RecT k59_1239_4 1537917.JU82_09980 4.99e-23 93.2 2ARVA@1|root,31H70@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - HK97-gp10_like k59_224962_1 511.JT27_00670 1.82e-35 132.0 2CI1J@1|root,32S73@2|Bacteria,1N528@1224|Proteobacteria,2VYZ1@28216|Betaproteobacteria,3T65K@506|Alcaligenaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_75753_1 926550.CLDAP_22220 1.87e-09 63.2 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2G5J0@200795|Chloroflexi 200795|Chloroflexi L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_26048_1 1385658.U5KPZ6_9VIRU 2.31e-72 239.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_17363_1 32264.tetur04g06460.1 1.92e-08 62.4 KOG3714@1|root,KOG3714@2759|Eukaryota,39URU@33154|Opisthokonta,3BFDN@33208|Metazoa,3D4ED@33213|Bilateria,41YM1@6656|Arthropoda 33208|Metazoa O It is involved in the biological process described with proteolysis - - - - - - - - - - - - Astacin k59_67367_2 1307759.JOMJ01000003_gene1802 5.45e-90 290.0 COG5565@1|root,COG5565@2|Bacteria,1R6R3@1224|Proteobacteria,43BCR@68525|delta/epsilon subdivisions,2X6RN@28221|Deltaproteobacteria,2MA58@213115|Desulfovibrionales 28221|Deltaproteobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C k59_125537_4 1234888.K0A2J2_9VIRU 4.02e-35 143.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_142120_1 160488.PP_3042 1.16e-43 165.0 COG5525@1|root,COG5525@2|Bacteria,1MVS3@1224|Proteobacteria,1RRH5@1236|Gammaproteobacteria,1YWJB@136845|Pseudomonas putida group 1236|Gammaproteobacteria S Phage terminase large subunit (GpA) - - - - - - - - - - - - Terminase_GpA k59_199961_1 105154.Q9MBU6_9VIRU 1.52e-17 82.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_192132_1 1121396.KB893101_gene494 1.47e-08 62.8 COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,42N7D@68525|delta/epsilon subdivisions,2WKJS@28221|Deltaproteobacteria,2MPWR@213118|Desulfobacterales 28221|Deltaproteobacteria O Subtilase family - - - - - - - - - - - - Big_3_2,Big_3_3,Inhibitor_I9,Peptidase_S8 k59_134579_2 218284.CCDN010000001_gene906 5.8e-12 66.6 COG4570@1|root,COG4570@2|Bacteria,1VF2H@1239|Firmicutes,4HJ0V@91061|Bacilli,1ZHF6@1386|Bacillus 91061|Bacilli L Endodeoxyribonuclease RusA rusA - - - - - - - - - - - RusA k59_167752_1 1618236.A0A0C5IB23_9CIRC 7e-40 150.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_167752_2 1379708.S5SYC3_9CIRC 5.7e-15 80.1 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_101228_1 575540.Isop_3001 1.69e-06 55.1 COG4974@1|root,COG4974@2|Bacteria,2IX6A@203682|Planctomycetes 203682|Planctomycetes D Belongs to the 'phage' integrase family. XerC subfamily - - - ko:K03733 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase k59_2067_1 1366055.S5M3Y0_9CAUD 2.77e-25 99.8 4QB2U@10239|Viruses,4QVJC@35237|dsDNA viruses no RNA stage,4QTMH@28883|Caudovirales 28883|Caudovirales S Pfam:GTA_holin_3TM - - - - - - - - - - - - - k59_2067_2 1035191.HMPREF0185_01795 3.5e-17 80.5 2E6PI@1|root,3319W@2|Bacteria,1RCIK@1224|Proteobacteria,2UFSS@28211|Alphaproteobacteria,2KJ8M@204458|Caulobacterales 204458|Caulobacterales - - - - - - - - - - - - - - - k59_225847_1 665956.HMPREF1032_02256 5.89e-09 62.8 COG5283@1|root,COG5412@1|root,COG5283@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,247QT@186801|Clostridia,3WH3F@541000|Ruminococcaceae 186801|Clostridia E Phage tail tape measure protein, TP901 family - - - - - - - - - - - - PhageMin_Tail k59_217827_2 1298858.AUEL01000029_gene39 3.08e-07 59.7 COG4725@1|root,COG4725@2|Bacteria,1R553@1224|Proteobacteria,2TRP6@28211|Alphaproteobacteria,43KW8@69277|Phyllobacteriaceae 28211|Alphaproteobacteria KT MT-A70 - - - - - - - - - - - - MT-A70,ParBc k59_134589_1 1327970.R9ZXU8_9CAUD 7.48e-09 57.8 4QFZ4@10239|Viruses,4QWCA@35237|dsDNA viruses no RNA stage,4QPIG@28883|Caudovirales,4QMKQ@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_158981_1 395495.Lcho_0484 6.9e-18 84.7 COG2227@1|root,COG2520@1|root,COG2227@2|Bacteria,COG2520@2|Bacteria 2|Bacteria J tRNA (guanine(37)-N(1))-methyltransferase activity - - - - - - - - - - - - Glycos_transf_2,Methyltransf_11,Methyltransf_21,Methyltransf_23,Methyltransf_25 k59_208814_1 1556290.A0A0A0RT35_9CAUD 6.94e-50 173.0 4QAWG@10239|Viruses,4QPII@28883|Caudovirales,4QKWY@10699|Siphoviridae 10699|Siphoviridae S DNA helicase activity - - - - - - - - - - - - - k59_200699_1 391008.Smal_2489 2.65e-32 136.0 COG5281@1|root,COG5281@2|Bacteria,1QUCD@1224|Proteobacteria,1T1T2@1236|Gammaproteobacteria,1XD9Q@135614|Xanthomonadales 135614|Xanthomonadales S tape measure protein - - - - - - - - - - - - - k59_9948_3 1239384.K4MPY5_9CAUD 5.36e-11 64.7 4QCCZ@10239|Viruses,4QYIM@35237|dsDNA viruses no RNA stage,4QQNX@28883|Caudovirales 28883|Caudovirales S virion - - - - - - - - - - - - - k59_9948_4 742733.HMPREF9469_05037 3.75e-26 100.0 2BD7A@1|root,326VE@2|Bacteria,1USRB@1239|Firmicutes,25ASG@186801|Clostridia,223BG@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_9948_5 665956.HMPREF1032_00668 7.75e-28 104.0 2AIHK@1|root,318ZG@2|Bacteria,1V7P0@1239|Firmicutes,24KNU@186801|Clostridia,3WNH7@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_259220_1 1636270.A0A0E3JPE6_9CAUD 2.93e-40 142.0 4QB55@10239|Viruses,4QSJ0@28883|Caudovirales,4QNGX@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_259220_2 1112216.JH594425_gene1957 8.79e-28 111.0 2BHYZ@1|root,32C3A@2|Bacteria,1PZ9T@1224|Proteobacteria,2V3ER@28211|Alphaproteobacteria,2KB8W@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - k59_242839_1 1410650.JHWL01000003_gene2852 2.72e-09 63.2 28XPA@1|root,2ZJK5@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_127356_1 1609634.A0A0C5AFT2_9VIRU 2.81e-73 233.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_135445_2 1415145.V5Q7M3_9CAUD 4.18e-18 85.1 4QBMV@10239|Viruses,4QUU6@35237|dsDNA viruses no RNA stage,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_52549_1 1112217.PPL19_19897 3.46e-11 68.6 COG4643@1|root,COG5545@1|root,COG4643@2|Bacteria,COG5545@2|Bacteria,1MVGK@1224|Proteobacteria,1SAWT@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Virulence-associated protein E - - - ko:K06919 - - - - ko00000 - - - VirE k59_102059_1 666681.M301_0132 7.25e-07 55.8 2D784@1|root,32TNH@2|Bacteria,1N098@1224|Proteobacteria,2VX0M@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_218816_1 1234888.K0A2J2_9VIRU 2.5e-26 107.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_192780_1 257310.BB1661 2.21e-56 187.0 COG0582@1|root,COG0582@2|Bacteria,1QB64@1224|Proteobacteria,2VRP1@28216|Betaproteobacteria,3T1G1@506|Alcaligenaceae 28216|Betaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_integrase k59_60294_4 1235661.K0IK58_9CAUD 1.94e-34 131.0 4QNC3@10744|Podoviridae 10744|Podoviridae S endonuclease activity - - - - - - - - - - - - - k59_176526_1 109760.SPPG_05522T0 1.39e-11 71.6 COG0187@1|root,KOG0355@2759|Eukaryota,38CPA@33154|Opisthokonta,3NWYX@4751|Fungi 4751|Fungi B Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks TOP2 GO:0000003,GO:0000018,GO:0000019,GO:0000070,GO:0000075,GO:0000166,GO:0000228,GO:0000278,GO:0000280,GO:0000712,GO:0000775,GO:0000785,GO:0000790,GO:0000793,GO:0000794,GO:0000795,GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005739,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006265,GO:0006271,GO:0006275,GO:0006310,GO:0006323,GO:0006325,GO:0006333,GO:0006338,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007076,GO:0007093,GO:0007127,GO:0007131,GO:0007346,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022402,GO:0022414,GO:0022616,GO:0030261,GO:0030554,GO:0031055,GO:0031323,GO:0031326,GO:0031570,GO:0031974,GO:0031981,GO:0032553,GO:0032555,GO:0032559,GO:0034506,GO:0034641,GO:0034645,GO:0035327,GO:0035639,GO:0035825,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044454,GO:0044464,GO:0044774,GO:0045132,GO:0045786,GO:0045930,GO:0046483,GO:0048285,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0051276,GO:0051304,GO:0051306,GO:0051307,GO:0051321,GO:0051726,GO:0060255,GO:0061505,GO:0061982,GO:0065007,GO:0070013,GO:0071103,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090329,GO:0097046,GO:0097047,GO:0097159,GO:0097367,GO:0098687,GO:0098813,GO:0099086,GO:0140013,GO:0140014,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:1903046,GO:1903047,GO:2000112,GO:2000621 5.99.1.3 ko:K03164 ko01524,map01524 - - - ko00000,ko00001,ko01000,ko03032,ko03036 - - - DNA_gyraseB,DNA_topoisoIV,HATPase_c,TOPRIM_C,Toprim k59_119238_3 525368.HMPREF0591_4797 3.91e-14 71.6 2DYV8@1|root,32V63@2|Bacteria,2GRK5@201174|Actinobacteria,23EHA@1762|Mycobacteriaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_44175_1 1385658.U5KPZ6_9VIRU 1.79e-39 145.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_226613_1 482537.XP_008569757.1 1.16e-32 129.0 COG1088@1|root,KOG0747@2759|Eukaryota,39ADA@33154|Opisthokonta,3BF2W@33208|Metazoa,3CWS2@33213|Bilateria,484W4@7711|Chordata,4926F@7742|Vertebrata,3J8K7@40674|Mammalia,35B91@314146|Euarchontoglires 33208|Metazoa G dTDP-glucose 4,6-dehydratase activity TGDS - 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd k59_93638_1 1367847.JCM7686_1017 9.35e-47 180.0 2CV95@1|root,32SX6@2|Bacteria,1N2KM@1224|Proteobacteria,2UEE5@28211|Alphaproteobacteria,2PWVC@265|Paracoccus 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_10612_2 717785.HYPMC_1239 2.1e-28 113.0 2CK1H@1|root,33WMM@2|Bacteria,1RF5H@1224|Proteobacteria,2UMV7@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF4043) - - - - - - - - - - - - DUF4043 k59_152274_2 1158150.KB906242_gene210 1.77e-21 98.6 COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1QWI1@1224|Proteobacteria,1RZ7K@1236|Gammaproteobacteria,1X1UJ@135613|Chromatiales 135613|Chromatiales L Toprim-like - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - DnaB_C k59_260809_1 1168547.L7P648_9CIRC 4.13e-29 118.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_260893_1 1094980.Mpsy_0568 1.8e-82 259.0 COG5410@1|root,arCOG09550@2157|Archaea 2157|Archaea K chromosome segregation - - - - - - - - - - - - Terminase_6,Terminase_6C k59_136404_1 395492.Rleg2_2429 8.11e-11 67.8 COG3566@1|root,COG3566@2|Bacteria,1REIQ@1224|Proteobacteria,2U9XH@28211|Alphaproteobacteria,4BCNB@82115|Rhizobiaceae 28211|Alphaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2213) - - - ko:K09960 - - - - ko00000 - - - DUF2213 k59_119967_10 1121456.ATVA01000014_gene640 1.08e-55 202.0 28HPK@1|root,2Z7XJ@2|Bacteria,1NBHR@1224|Proteobacteria,42YKK@68525|delta/epsilon subdivisions,2WUDS@28221|Deltaproteobacteria,2M8E7@213115|Desulfovibrionales 28221|Deltaproteobacteria S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_119967_14 1283077.M1I7J8_9CAUD 6.19e-85 271.0 4QCWX@10239|Viruses,4QW0V@35237|dsDNA viruses no RNA stage,4QR4Y@28883|Caudovirales,4QP36@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_61038_1 314260.PB2503_06572 1.59e-62 214.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2TS19@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdA - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - RNR_N,Ribonuc_red_lgC,Ribonuc_red_lgN k59_185990_1 742918.D4N3P2_9CIRC 4.67e-08 60.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_193769_1 1150626.PHAMO_80087 2.98e-15 82.8 COG3941@1|root,COG3941@2|Bacteria,1PHQP@1224|Proteobacteria,2V9RW@28211|Alphaproteobacteria,2JWSI@204441|Rhodospirillales 204441|Rhodospirillales S Lambda phage tail tape-measure protein (Tape_meas_lam_C) - - - - - - - - - - - - Tape_meas_lam_C k59_119968_1 1122201.AUAZ01000017_gene2960 8.59e-35 135.0 COG5362@1|root,COG5362@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Terminase_6C k59_210323_1 1609634.A0A0C5AFT2_9VIRU 4.62e-38 142.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_227617_4 608538.HTH_0548 1.06e-49 174.0 2A75B@1|root,30W16@2|Bacteria,2G5D4@200783|Aquificae 200783|Aquificae S Family of unknown function (DUF5309) - - - - - - - - - - - - DUF5309 k59_94392_3 313612.L8106_16049 0.000296 50.4 COG3409@1|root,COG4990@1|root,COG3409@2|Bacteria,COG4990@2|Bacteria,1G4XP@1117|Cyanobacteria,1HAVP@1150|Oscillatoriales 1117|Cyanobacteria M Peptidase M15B M15C, D,D-carboxypeptidase VanY endolysins - - - - - - - - - - - - PG_binding_1,VanY k59_128546_1 941449.dsx2_2649 1.22e-29 124.0 28IJ1@1|root,2Z8K0@2|Bacteria,1R5PC@1224|Proteobacteria,435JM@68525|delta/epsilon subdivisions,2WZXR@28221|Deltaproteobacteria,2M8CX@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_153355_1 1267535.KB906767_gene167 2.56e-09 63.2 2A05Q@1|root,30N8J@2|Bacteria,3Y84W@57723|Acidobacteria,2JNCP@204432|Acidobacteriia 204432|Acidobacteriia - - - - - - - - - - - - - - Tape_meas_lam_C k59_193777_1 1476390.A0A060RJ50_9CAUD 8.5e-13 76.6 4QBSJ@10239|Viruses,4QXH4@35237|dsDNA viruses no RNA stage,4QPFJ@28883|Caudovirales,4QKUK@10699|Siphoviridae 10699|Siphoviridae S DNA primase activity - - - - - - - - - - - - - k59_11450_1 1986029.Q9MBM3_9VIRU 9.78e-39 142.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_104049_1 1120985.AUMI01000018_gene2930 3.4e-06 53.5 COG1573@1|root,COG1573@2|Bacteria,1V267@1239|Firmicutes,4H3WV@909932|Negativicutes 909932|Negativicutes L Uracil-DNA glycosylase - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k59_252891_4 1121935.AQXX01000130_gene2431 5.08e-29 113.0 2EUDH@1|root,33MVW@2|Bacteria,1NVTR@1224|Proteobacteria,1SP33@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_121280_1 1692258.A0A0K1RL51_9CIRC 4.49e-78 244.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_261969_1 1094508.Tsac_0966 1.45e-06 59.3 COG0209@1|root,COG1372@1|root,COG0209@2|Bacteria,COG1372@2|Bacteria,1TPFH@1239|Firmicutes,249EN@186801|Clostridia,42F6G@68295|Thermoanaerobacterales 186801|Clostridia F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrdJ - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Intein_splicing,LAGLIDADG_3,Ribonuc_red_2_N,Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD k59_113201_1 1692258.A0A0K1RL51_9CIRC 1.12e-24 102.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_113388_1 204773.HEAR2272 2.05e-14 81.6 2CENN@1|root,32VYV@2|Bacteria,1N4RC@1224|Proteobacteria,2W1J6@28216|Betaproteobacteria,476WV@75682|Oxalobacteraceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_204195_2 202954.BBNK01000034_gene3794 1.07e-29 110.0 2A3Q7@1|root,30S7S@2|Bacteria,1NP2K@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_179078_1 1055815.AYYA01000026_gene534 7.66e-08 52.8 COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,1RPB7@1236|Gammaproteobacteria,3NJ6E@468|Moraxellaceae 1236|Gammaproteobacteria E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) aroE GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_3165,iECOK1_1307.ECOK1_3701,iECS88_1305.ECS88_3669,iECUMN_1333.ECUMN_3755,iSBO_1134.SBO_3275,iUMN146_1321.UM146_16315,iUTI89_1310.UTI89_C3726 Shikimate_DH,Shikimate_dh_N k59_179078_2 1055815.AYYA01000026_gene532 3.23e-54 181.0 COG0115@1|root,COG0115@2|Bacteria,1MZAK@1224|Proteobacteria,1RPPG@1236|Gammaproteobacteria,3NIK0@468|Moraxellaceae 1236|Gammaproteobacteria EH Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase pabC GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008696,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0019842,GO:0030170,GO:0034641,GO:0036094,GO:0042558,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564 4.1.3.38 ko:K02619 ko00790,map00790 - R05553 RC01843,RC02148 ko00000,ko00001,ko01000 - - iAPECO1_1312.APECO1_177,iE2348C_1286.E2348C_1188,iECED1_1282.ECED1_1239,iECNA114_1301.ECNA114_1153,iECOK1_1307.ECOK1_1203,iECS88_1305.ECS88_1110,iECSF_1327.ECSF_0995,iECUMN_1333.ECUMN_1273,iJN746.PP_1917,iPC815.YPO1603,iUMN146_1321.UM146_11845,iUTI89_1310.UTI89_C1222,ic_1306.c1366 Aminotran_4 k59_195066_1 1286171.EAL2_c01150 7.64e-22 102.0 COG0209@1|root,COG0209@2|Bacteria,1TT3U@1239|Firmicutes,24C4U@186801|Clostridia 186801|Clostridia F TIGRFAM ribonucleoside-triphosphate reductase, adenosylcobalamin-dependent - - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,Ribonuc_red_lgC k59_154636_2 234267.Acid_6941 1.53e-10 66.6 COG3064@1|root,COG4627@1|root,COG3064@2|Bacteria,COG4627@2|Bacteria 2|Bacteria M translation initiation factor activity - - - ko:K08307,ko:K19140 - - - - ko00000,ko01000,ko01011,ko02048 - - - DDE_Tnp_1,DUF772,Methyltransf_11 k59_31293_1 794903.OPIT5_04015 8.87e-28 110.0 2CJW6@1|root,32SAX@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_263010_1 665942.HMPREF1022_00141 2.26e-35 141.0 28HPK@1|root,2Z7XJ@2|Bacteria,1NBHR@1224|Proteobacteria,42YKK@68525|delta/epsilon subdivisions,2WUDS@28221|Deltaproteobacteria,2M8E7@213115|Desulfovibrionales 28221|Deltaproteobacteria S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_212279_1 469617.FUAG_01566 1.3e-46 160.0 COG0451@1|root,COG0451@2|Bacteria,378E5@32066|Fusobacteria 32066|Fusobacteria M Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction fcl - 1.1.1.271 ko:K02377 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R05692 RC01014 ko00000,ko00001,ko01000 - - - Epimerase k59_114510_1 1121468.AUBR01000007_gene299 7.03e-65 219.0 COG0863@1|root,COG0863@2|Bacteria,1TR56@1239|Firmicutes,248NR@186801|Clostridia 186801|Clostridia L Belongs to the N(4) N(6)-methyltransferase family cfr9IM - 2.1.1.113 ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_114510_4 1392540.P256_00045 2.97e-32 115.0 2BRZC@1|root,32KZQ@2|Bacteria,1Q31I@1224|Proteobacteria,1RSVN@1236|Gammaproteobacteria,3NRT9@468|Moraxellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_163120_1 109760.SPPG_05243T0 2.25e-24 109.0 COG5108@1|root,KOG1038@2759|Eukaryota,38EAY@33154|Opisthokonta,3NU1C@4751|Fungi 4751|Fungi KL DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates RPO41 GO:0000002,GO:0000428,GO:0000959,GO:0001018,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006351,GO:0006390,GO:0006725,GO:0006807,GO:0006996,GO:0007005,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0031974,GO:0032774,GO:0032991,GO:0034062,GO:0034245,GO:0034641,GO:0034645,GO:0034654,GO:0042645,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0061695,GO:0070013,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097659,GO:0097747,GO:0098798,GO:0140053,GO:0140098,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K10908 - - - - ko00000,ko01000,ko03029 - - - RNA_pol,RPOL_N k59_122702_1 1316932.MHH_c17930 2.85e-27 115.0 COG3567@1|root,COG3567@2|Bacteria,1R45U@1224|Proteobacteria,1RY7G@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF1073) - - - ko:K09961 - - - - ko00000 - - - DUF1073 k59_229888_1 1341181.FLJC2902T_17310 2.65e-104 319.0 COG0270@1|root,COG0270@2|Bacteria,4NH5Z@976|Bacteroidetes,1ID39@117743|Flavobacteriia,2NX4R@237|Flavobacterium 976|Bacteroidetes L C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_21655_1 935261.JAGL01000009_gene1165 7.87e-58 199.0 COG0209@1|root,COG0209@2|Bacteria,1PM78@1224|Proteobacteria,2UZUM@28211|Alphaproteobacteria,43QGW@69277|Phyllobacteriaceae 28211|Alphaproteobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides - - - - - - - - - - - - - k59_238069_2 1402135.SUH3_12045 0.000207 46.6 COG3772@1|root,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,2U8JK@28211|Alphaproteobacteria,3ZWVW@60136|Sulfitobacter 28211|Alphaproteobacteria G Phage lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_230930_1 1449976.KALB_4853 9.02e-08 57.4 COG0629@1|root,COG0629@2|Bacteria,2IR4I@201174|Actinobacteria,4ECNJ@85010|Pseudonocardiales 201174|Actinobacteria L ERF superfamily - - - - - - - - - - - - ERF k59_140317_2 7209.EFO25451.1 5.06e-09 63.5 2EWQP@1|root,2SYH6@2759|Eukaryota 2759|Eukaryota S RNA helicase - - - - - - - - - - - - RNA_helicase,Viral_Rep k59_149088_1 490913.C4NTG0_9CAUD 1.12e-09 58.2 4QFVM@10239|Viruses,4QZ9I@35237|dsDNA viruses no RNA stage,4QRXV@28883|Caudovirales,4QNS4@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_32719_3 1116482.K9L536_9CAUD 0.000316 45.1 4QBY1@10239|Viruses,4QZSN@35237|dsDNA viruses no RNA stage,4QS4Q@28883|Caudovirales,4QK9A@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_123793_3 478749.BRYFOR_08524 8.38e-60 201.0 COG4626@1|root,COG4626@2|Bacteria,1TT9I@1239|Firmicutes,24AFK@186801|Clostridia 186801|Clostridia S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - Terminase_1 k59_246525_1 1500257.JQNM01000006_gene1746 4.9e-08 60.8 2DSWE@1|root,33HPD@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_246525_3 999141.GME_16357 2.94e-17 95.1 2DZHM@1|root,32VAY@2|Bacteria,1N0DC@1224|Proteobacteria,1SP9I@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_149092_1 1041159.AZUW01000001_gene3281 0.000285 50.1 2DQJ1@1|root,3376F@2|Bacteria,1RKWB@1224|Proteobacteria,2UA4H@28211|Alphaproteobacteria,4BE0C@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - Beta_helix,Pectate_lyase_3 k59_181158_3 665942.HMPREF1022_03262 5.82e-15 71.2 2AUG0@1|root,31K47@2|Bacteria,1P7NZ@1224|Proteobacteria,4339N@68525|delta/epsilon subdivisions,2WY3A@28221|Deltaproteobacteria,2ME32@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_164225_1 1280944.HY17_04705 8.92e-10 68.6 2E8SI@1|root,3333B@2|Bacteria,1N7MG@1224|Proteobacteria,2UJSF@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_39529_1 1122223.KB890687_gene2408 4.48e-11 62.4 COG1476@1|root,COG1476@2|Bacteria,1WNGE@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus K Cro/C1-type HTH DNA-binding domain - - - - - - - - - - - - HTH_3 k59_123796_1 399742.Ent638_2235 2.14e-55 188.0 COG4695@1|root,COG4695@2|Bacteria,1PFTD@1224|Proteobacteria,1RTWZ@1236|Gammaproteobacteria,3X3J3@547|Enterobacter 1236|Gammaproteobacteria S Portal protein - - - - - - - - - - - - - k59_123796_2 1123020.AUIE01000007_gene3232 8.97e-25 97.8 2EI3E@1|root,33BUW@2|Bacteria,1NGUW@1224|Proteobacteria,1ST4E@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage gp6-like head-tail connector protein - - - - - - - - - - - - Phage_connect_1 k59_14583_2 490913.C4NTF2_9CAUD 2.13e-48 164.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QNX8@10744|Podoviridae 10744|Podoviridae S N-acetylmuramoyl-L-alanine amidase activity - GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0008150,GO:0008745,GO:0016032,GO:0016787,GO:0016810,GO:0016811,GO:0019048,GO:0019058,GO:0019076,GO:0031640,GO:0032897,GO:0035821,GO:0035890,GO:0035891,GO:0039633,GO:0040011,GO:0043900,GO:0043901,GO:0043903,GO:0044003,GO:0044004,GO:0044364,GO:0044403,GO:0044419,GO:0044659,GO:0044661,GO:0046782,GO:0048519,GO:0048525,GO:0050789,GO:0050792,GO:0051701,GO:0051704,GO:0051817,GO:0051818,GO:0051883,GO:0052126,GO:0052192,GO:0061783,GO:0065007 - - - - - - - - - - - k59_123797_1 445688.E3SNL6_9CAUD 9.2e-25 111.0 4QGP7@10239|Viruses,4QQ0Q@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_264415_1 748280.NH8B_0537 6.71e-45 160.0 2DCM2@1|root,32TZV@2|Bacteria,1NAGE@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_88404_1 1410676.JNKL01000004_gene623 4.2e-22 96.3 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576 - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_23959_3 1051675.G0YQH7_9CAUD 5.27e-200 562.0 4QGGR@10239|Viruses,4QZHR@35237|dsDNA viruses no RNA stage,4QUGZ@28883|Caudovirales,4QNY3@10744|Podoviridae 10744|Podoviridae S viral capsid - - - - - - - - - - - - - k59_57938_1 1380394.JADL01000001_gene2581 2.87e-10 67.4 COG5565@1|root,COG5565@2|Bacteria,1R6R3@1224|Proteobacteria,2U1P9@28211|Alphaproteobacteria,2JX6C@204441|Rhodospirillales 204441|Rhodospirillales S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_23961_1 265729.GS18_0213905 6.87e-42 149.0 COG2877@1|root,COG2877@2|Bacteria,1TR2G@1239|Firmicutes,4HTSS@91061|Bacilli,1ZE1D@1386|Bacillus 91061|Bacilli M Belongs to the KdsA family kdsA - 2.5.1.55 ko:K01627 ko00540,ko01100,map00540,map01100 M00063 R03254 RC00435 ko00000,ko00001,ko00002,ko01000,ko01005 - - - DAHP_synth_1 k59_231832_2 33035.JPJF01000011_gene1265 1.92e-06 57.4 COG4974@1|root,COG4974@2|Bacteria,1TY7M@1239|Firmicutes,24BN9@186801|Clostridia 186801|Clostridia L Psort location Cytoplasmic, score - - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase k59_214374_1 1114964.L485_00905 2.66e-45 163.0 COG1061@1|root,COG1061@2|Bacteria,1MV9F@1224|Proteobacteria,2TUXC@28211|Alphaproteobacteria,2K4Z7@204457|Sphingomonadales 204457|Sphingomonadales KL helicase superfamily c-terminal domain - - - - - - - - - - - - Helicase_C,ResIII k59_106918_1 1304878.AUGD01000009_gene6390 3.96e-15 71.6 2AKH8@1|root,31B97@2|Bacteria,1NYNN@1224|Proteobacteria,2UTCA@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_106918_2 1123508.JH636439_gene1604 3.39e-11 62.4 29XN2@1|root,30JDF@2|Bacteria,2J498@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - k59_182029_2 186617.M9M8L2_9VIRU 1.11e-100 306.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_40505_1 1283071.R9R5B2_9CAUD 2.66e-81 261.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_231842_1 592316.Pat9b_2108 1.28e-24 109.0 COG4733@1|root,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria,1RNFD@1236|Gammaproteobacteria,3VXR4@53335|Pantoea 1236|Gammaproteobacteria S Fibronectin type 3 domain - - - - - - - - - - - - DUF1983,DUF3672,Phage-tail_3 k59_232052_1 1122137.AQXF01000001_gene2524 2.65e-65 214.0 COG5323@1|root,COG5323@2|Bacteria,1MW8S@1224|Proteobacteria,2TREI@28211|Alphaproteobacteria 28211|Alphaproteobacteria S ATP-binding protein' - - - - - - - - - - - - Terminase_3,Terminase_6,Terminase_6C k59_256222_5 926549.KI421517_gene2345 8.38e-15 75.5 COG1783@1|root,COG1783@2|Bacteria,4PMA2@976|Bacteroidetes,47RRH@768503|Cytophagia 976|Bacteroidetes S Terminase RNAseH like domain - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C k59_232057_1 1380394.JADL01000006_gene5258 1.93e-89 273.0 28NGF@1|root,2ZBII@2|Bacteria,1R9KY@1224|Proteobacteria,2U1P7@28211|Alphaproteobacteria,2JXPF@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - k59_107064_2 1300143.CCAV010000006_gene4313 1.76e-48 168.0 29D2S@1|root,3000U@2|Bacteria,4PGQF@976|Bacteroidetes,1IM4Y@117743|Flavobacteriia,3ZSNA@59732|Chryseobacterium 976|Bacteroidetes - - - - - - - - - - - - - - - k59_49878_1 153496.JNAB01000022_gene2627 1.67e-07 53.9 COG1783@1|root,COG1783@2|Bacteria,1R66A@1224|Proteobacteria,2TV42@28211|Alphaproteobacteria,2JXEM@204441|Rhodospirillales 204441|Rhodospirillales S Terminase-like family - - - - - - - - - - - - - k59_49878_2 1121438.JNJA01000001_gene2622 1.12e-12 65.9 2D0K9@1|root,32T8S@2|Bacteria,1MZRW@1224|Proteobacteria,42WKB@68525|delta/epsilon subdivisions,2WRMI@28221|Deltaproteobacteria,2MF33@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_257202_2 1692249.A0A0K1RL40_9CIRC 1.33e-48 168.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_8438_1 1540097.A0A0A0YU90_9CAUD 1.65e-22 95.1 4QDXM@10239|Viruses,4QQF6@28883|Caudovirales,4QNXH@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_215719_3 1609634.A0A0C5AFT2_9VIRU 4.62e-124 366.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_215719_7 1609634.A0A0C5ANA6_9VIRU 6.72e-14 77.0 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_215719_8 1385658.U5KPZ6_9VIRU 2.02e-135 407.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_58237_2 742733.HMPREF9469_05041 1.09e-30 111.0 2CGGB@1|root,32UNH@2|Bacteria,1VD9W@1239|Firmicutes,24MWC@186801|Clostridia,2235P@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_108068_1 391589.RGAI101_335 1.95e-06 48.9 2EK5N@1|root,33DW2@2|Bacteria,1NHDG@1224|Proteobacteria,2UJBG@28211|Alphaproteobacteria,2P404@2433|Roseobacter 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_215833_1 1304878.AUGD01000002_gene1857 2.7e-23 95.1 2C58H@1|root,32YYI@2|Bacteria,1N7UA@1224|Proteobacteria,2UHCE@28211|Alphaproteobacteria,3K1T7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S NinB protein - - - - - - - - - - - - NinB k59_249021_1 630626.EBL_c21750 1.74e-30 124.0 28J9D@1|root,2Z94E@2|Bacteria,1QE0C@1224|Proteobacteria,1RZ22@1236|Gammaproteobacteria 1236|Gammaproteobacteria S P22 coat protein - gene protein 5 - - - - - - - - - - - - P22_CoatProtein k59_116355_1 652103.Rpdx1_2992 4.36e-56 197.0 COG5108@1|root,COG5108@2|Bacteria,1PIWB@1224|Proteobacteria,2U1JR@28211|Alphaproteobacteria 28211|Alphaproteobacteria K DNA-dependent RNA polymerase - - - - - - - - - - - - RNA_pol,RPOL_N k59_66505_1 1219035.NT2_13_00580 1.55e-22 100.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_41692_4 1618242.A0A0C5IBR9_9CIRC 2.57e-28 120.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_257982_1 1552758.NC00_01265 3.45e-80 265.0 COG3567@1|root,COG3567@2|Bacteria,1QNPU@1224|Proteobacteria,1S4PU@1236|Gammaproteobacteria,1X7HW@135614|Xanthomonadales 135614|Xanthomonadales S to SP P44183 (percent identity 30 query alignment coverage 92.9 subject alignment coverage 99.5 - - - ko:K09961 - - - - ko00000 - - - DUF1073 k59_216517_3 105154.Q9MBU3_9VIRU 1.96e-13 74.3 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_83642_3 645099.MREP_BBTVA 2.01e-09 66.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_42284_1 1472912.A0A023NGD1_9CAUD 1.45e-35 141.0 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales 28883|Caudovirales S DnaB-like helicase C terminal domain - - - - - - - - - - - - - k59_133542_1 1410624.JNKK01000003_gene103 2.9e-54 183.0 COG0562@1|root,COG0562@2|Bacteria,1TQB9@1239|Firmicutes,249BR@186801|Clostridia,27IA3@186928|unclassified Lachnospiraceae 186801|Clostridia M UDP-galactopyranose mutase glf - 5.4.99.9 ko:K01854 ko00052,ko00520,map00052,map00520 - R00505,R09009 RC00317,RC02396 ko00000,ko00001,ko01000 - - - GLF,NAD_binding_8 k59_257991_2 1692244.A0A0K1RLR5_9CIRC 8.04e-86 267.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_166671_2 937777.Deipe_2101 5.33e-44 149.0 2BYEQ@1|root,32SXE@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_58792_2 1692250.A0A0K1RLR1_9CIRC 4.31e-15 75.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_25801_1 1574422.A0A0A1ENW9_9CIRC 1.72e-48 171.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_174633_2 105154.Q9MBU0_9VIRU 1.17e-36 140.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_174633_4 105154.Q9MBU6_9VIRU 1.07e-180 527.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_116905_1 1692250.A0A0K1RLR1_9CIRC 2.41e-70 223.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_199777_2 1219076.N646_0606 6.95e-19 82.0 2CHQ6@1|root,33N6R@2|Bacteria,1NM75@1224|Proteobacteria,1SUNZ@1236|Gammaproteobacteria,1Y1UP@135623|Vibrionales 1236|Gammaproteobacteria S Protein of unknown function (DUF2523) - - - - - - - - - - - - DUF2523 k59_125305_1 326442.PSHAa1557 8.12e-89 315.0 2DI1X@1|root,32UA7@2|Bacteria,1N6BQ@1224|Proteobacteria,1SBG2@1236|Gammaproteobacteria,2Q4VW@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_191970_2 1149133.ppKF707_0767 1.22e-29 122.0 COG5525@1|root,COG5525@2|Bacteria,1MVS3@1224|Proteobacteria,1RRH5@1236|Gammaproteobacteria,1YEHD@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Phage terminase large subunit (GpA) - - - - - - - - - - - - Terminase_GpA k59_109320_1 1219035.NT2_13_00580 1.21e-67 227.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_43130_2 298386.PBPRA1331 6.99e-33 118.0 2AFF0@1|root,315F0@2|Bacteria,1RHGE@1224|Proteobacteria,1S6YG@1236|Gammaproteobacteria,1Y17N@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k59_51382_1 1126411.I1TEL3_9CIRC 1.75e-10 65.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_84322_1 1379708.S5SYC3_9CIRC 4.17e-26 104.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_233451_1 1385658.U5KPZ6_9VIRU 1.5e-44 161.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_67917_12 1110502.TMO_2371 2.36e-36 159.0 COG5281@1|root,COG5281@2|Bacteria,1MX2R@1224|Proteobacteria,2U3WK@28211|Alphaproteobacteria,2JTUX@204441|Rhodospirillales 204441|Rhodospirillales D tape measure protein - - - - - - - - - - - - - k59_200458_1 1370122.JHXQ01000018_gene100 2.99e-22 97.8 COG1896@1|root,COG1896@2|Bacteria,1RACF@1224|Proteobacteria,2TUK3@28211|Alphaproteobacteria,4BGZB@82115|Rhizobiaceae 28211|Alphaproteobacteria S hydrolases of HD superfamily - - - ko:K06952 - - - - ko00000 - - - - k59_158952_2 1283071.R9R4H0_9CAUD 5.79e-28 110.0 4QEMD@10239|Viruses,4R0JN@35237|dsDNA viruses no RNA stage,4QUGF@28883|Caudovirales,4QNXF@10744|Podoviridae 10744|Podoviridae S AAA domain - - - - - - - - - - - - - k59_34923_1 445972.ANACOL_01831 5.27e-10 62.4 2ADP3@1|root,313E1@2|Bacteria,1W6J2@1239|Firmicutes,2572T@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_34923_2 1219035.NT2_15_00150 3.41e-08 53.9 COG0175@1|root,COG0175@2|Bacteria,1QZJ1@1224|Proteobacteria,2U233@28211|Alphaproteobacteria 28211|Alphaproteobacteria EH sulfate reduction - - - - - - - - - - - - - k59_126324_1 1123276.KB893251_gene3615 3.6e-07 52.8 COG0494@1|root,COG0494@2|Bacteria,4NR26@976|Bacteroidetes,47QYB@768503|Cytophagia 976|Bacteroidetes L nUDIX hydrolase - - - - - - - - - - - - - k59_126324_2 868131.MSWAN_0552 0.000509 44.3 COG1091@1|root,arCOG01367@2157|Archaea,2XVV7@28890|Euryarchaeota,23PC7@183925|Methanobacteria 183925|Methanobacteria M Male sterility protein - - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind k59_118069_1 1187851.A33M_3323 0.00048 50.1 COG0741@1|root,COG0741@2|Bacteria,1N5XK@1224|Proteobacteria,2UGUV@28211|Alphaproteobacteria 28211|Alphaproteobacteria M lytic transglycosylase activity - - - ko:K02395 - - - - ko00000,ko02035 - - - - k59_118069_2 864069.MicloDRAFT_00064820 1.44e-21 105.0 2D1N3@1|root,32TB0@2|Bacteria,1N49A@1224|Proteobacteria,2UCZB@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_184908_1 1219035.NT2_13_00580 3.04e-28 117.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_242877_2 329254.Q2NPF7_9CAUD 1.99e-28 108.0 4QB0U@10239|Viruses,4QZQJ@35237|dsDNA viruses no RNA stage,4QR5X@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_52752_6 595494.Tola_0336 7.17e-06 56.6 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1Y479@135624|Aeromonadales 135624|Aeromonadales L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_226697_1 1379725.S5SYG4_9CIRC 1.84e-47 163.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_168873_2 1385935.N836_31740 6.2e-33 130.0 COG0305@1|root,COG1372@1|root,COG0305@2|Bacteria,COG1372@2|Bacteria,1G0R8@1117|Cyanobacteria,1H75W@1150|Oscillatoriales 1117|Cyanobacteria L Participates in initiation and elongation during chromosome replication - - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3 k59_18841_1 1123279.ATUS01000005_gene3102 1.61e-84 269.0 2CJWY@1|root,31CWF@2|Bacteria,1RKEF@1224|Proteobacteria,1S75P@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_18841_2 1147150.K7PM60_9CAUD 3.2e-24 98.2 4QB1F@10239|Viruses,4QUYH@35237|dsDNA viruses no RNA stage,4QPSW@28883|Caudovirales,4QKPW@10699|Siphoviridae 10699|Siphoviridae S exonuclease activity - - - - - - - - - - - - - k59_69026_1 1452718.JBOY01000029_gene46 4.86e-67 219.0 28MVD@1|root,2ZB2Y@2|Bacteria,1R8NK@1224|Proteobacteria,1T01Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF4043) - - - - - - - - - - - - DUF4043 k59_10678_1 443143.GM18_2763 6.48e-13 69.7 COG0582@1|root,COG0582@2|Bacteria,1N59J@1224|Proteobacteria,42WQR@68525|delta/epsilon subdivisions,2WS30@28221|Deltaproteobacteria 28221|Deltaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_integrase k59_10678_2 159087.Daro_0797 6.08e-24 101.0 COG3617@1|root,COG3617@2|Bacteria,1N09A@1224|Proteobacteria,2W36F@28216|Betaproteobacteria,2KZMV@206389|Rhodocyclales 206389|Rhodocyclales K BRO family, N-terminal domain - - - - - - - - - - - - Bro-N k59_226702_1 1137799.GZ78_10890 9.68e-20 94.4 2DPH8@1|root,3322Q@2|Bacteria,1NF87@1224|Proteobacteria,1SFCH@1236|Gammaproteobacteria,1XQQC@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - Laminin_G_3 k59_127529_1 546273.VEIDISOL_00724 7.57e-22 106.0 COG5281@1|root,COG5281@2|Bacteria,1TPWF@1239|Firmicutes,4H3NF@909932|Negativicutes 909932|Negativicutes S tape measure - - - - - - - - - - - - - k59_102250_1 1618259.A0A0C5I2B5_9CIRC 5.03e-33 126.0 4QE84@10239|Viruses,4QUKR@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_144221_3 34506.g5911 5.48e-40 152.0 COG1875@1|root,2S7WC@2759|Eukaryota,3AIEB@33154|Opisthokonta,3BXHE@33208|Metazoa,3DD55@33213|Bilateria 33208|Metazoa T PhoH-like protein - - - - - - - - - - - - PhoH k59_260104_2 385682.AFSL01000096_gene613 0.000126 48.5 COG1179@1|root,COG1179@2|Bacteria,4NEKB@976|Bacteroidetes,2FMG4@200643|Bacteroidia,3XIVJ@558415|Marinilabiliaceae 976|Bacteroidetes H ThiF family hypB - - ko:K22132 - - - - ko00000,ko03016 - - - ThiF k59_18848_1 472175.EL18_01373 4.88e-78 249.0 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,2V9W4@28211|Alphaproteobacteria,43NEB@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Phage portal protein - - - - - - - - - - - - Phage_portal k59_3147_2 10228.TriadP52877 4.56e-23 101.0 2D04N@1|root,2SCSW@2759|Eukaryota,3AE35@33154|Opisthokonta 33154|Opisthokonta - - - - - - - - - - - - - - - k59_110706_2 1692255.A0A0K1RL52_9CIRC 1.75e-55 182.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_52769_1 1094755.MCO_00986 3.24e-09 63.2 2ERQ6@1|root,33851@2|Bacteria,1NKQW@1224|Proteobacteria,2UN9J@28211|Alphaproteobacteria,48TRX@772|Bartonellaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_160046_1 1385658.U5KPZ6_9VIRU 9.72e-63 209.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_3148_4 1297617.JPJD01000029_gene2358 1.43e-06 50.4 COG5377@1|root,COG5377@2|Bacteria,1TS2Y@1239|Firmicutes,249SB@186801|Clostridia,268K6@186813|unclassified Clostridiales 186801|Clostridia L YqaJ-like viral recombinase domain - - - - - - - - - - - - YqaJ k59_168887_1 259536.Psyc_1030 1.29e-33 136.0 COG5281@1|root,COG5281@2|Bacteria,1MX2R@1224|Proteobacteria,1S3MM@1236|Gammaproteobacteria,3NSS7@468|Moraxellaceae 1236|Gammaproteobacteria D tape measure protein Z012_10445 - - - - - - - - - - - Phage_HK97_TLTM,Tape_meas_lam_C k59_69034_1 1234888.K0A2J2_9VIRU 2.53e-69 227.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_78565_2 880073.Calab_3522 1.29e-05 53.9 COG4447@1|root,COG4447@2|Bacteria,2NRC1@2323|unclassified Bacteria 2|Bacteria S cellulose binding - - - - - - - - - - - - PSII_BNR k59_252108_1 1147044.H9A0L2_9CAUD 1.11e-10 67.8 4QG2D@10239|Viruses,4QY76@35237|dsDNA viruses no RNA stage,4QSXU@28883|Caudovirales,4QM4M@10699|Siphoviridae 10699|Siphoviridae S AAA domain - - - - - - - - - - - - - k59_128995_1 1540097.A0A0A0YU43_9CAUD 7.8e-21 97.8 4QBMV@10239|Viruses,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_161271_1 1096546.WYO_0201 1.87e-40 152.0 28P6A@1|root,2ZC10@2|Bacteria,1RBZE@1224|Proteobacteria,2UQEG@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_112121_1 1175654.A0A0S0N897_9CAUD 1.23e-62 211.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QM52@10699|Siphoviridae 10699|Siphoviridae S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor - - - - - - - - - - - - - k59_11961_2 575540.Isop_3007 7.92e-06 49.7 COG0727@1|root,COG0727@2|Bacteria,2IZM1@203682|Planctomycetes 203682|Planctomycetes S Putative zinc- or iron-chelating domain - - - ko:K06940 - - - - ko00000 - - - CxxCxxCC k59_19939_1 1234888.K0A2J2_9VIRU 1.06e-67 223.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_244085_2 114615.BRADO6930 3.69e-16 76.3 2EHBB@1|root,33B36@2|Bacteria,1RGAQ@1224|Proteobacteria,2U70Q@28211|Alphaproteobacteria,3JZ8Y@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_86116_2 1141519.H6VUA7_9CAUD 1.36e-10 63.5 4QBMV@10239|Viruses,4QUU6@35237|dsDNA viruses no RNA stage,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_103356_5 266762.HQ36_02045 5.95e-05 50.8 COG0749@1|root,COG0749@2|Bacteria,4PK8J@976|Bacteroidetes,2FU9T@200643|Bacteroidia 976|Bacteroidetes L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity - - - - - - - - - - - - DNA_pol_A k59_120501_3 1609634.A0A0C5AFV4_9VIRU 5.3e-39 144.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_146752_2 1385658.U5KPZ6_9VIRU 8.83e-66 216.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_104215_1 1265502.KB905988_gene44 1.97e-26 114.0 COG3378@1|root,COG3378@2|Bacteria,1MV7I@1224|Proteobacteria,2VM9Y@28216|Betaproteobacteria,4ABPN@80864|Comamonadaceae 28216|Betaproteobacteria S D5 N terminal like - - - ko:K06919 - - - - ko00000 - - - D5_N,PriCT_2 k59_95490_1 547042.BACCOPRO_02130 2.01e-23 99.4 28K97@1|root,2Z9WV@2|Bacteria,4P1GF@976|Bacteroidetes,2FS5S@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_137888_1 1208323.B30_05227 3.3e-06 48.9 COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,2TQSB@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA - 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt k59_137888_4 227470.Q76Z75_9CAUD 5.56e-29 115.0 4QASV@10239|Viruses,4QWD9@35237|dsDNA viruses no RNA stage,4QQ4N@28883|Caudovirales,4QIBN@10662|Myoviridae 10662|Myoviridae S recA bacterial DNA recombination protein - - - - - - - - - - - - - k59_262322_1 266835.14021429 5.01e-101 311.0 COG1783@1|root,COG1783@2|Bacteria,1MVJB@1224|Proteobacteria,2U2BM@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6 k59_20822_1 246194.CHY_0676 2.29e-05 55.8 COG0209@1|root,COG1372@1|root,COG1594@1|root,COG0209@2|Bacteria,COG1372@2|Bacteria,COG1594@2|Bacteria,1TPFH@1239|Firmicutes,249EN@186801|Clostridia,42F6G@68295|Thermoanaerobacterales 186801|Clostridia F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrdJ - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Intein_splicing,LAGLIDADG_3,Ribonuc_red_2_N,Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD k59_30452_1 438753.AZC_3607 1.74e-168 506.0 COG5108@1|root,COG5108@2|Bacteria,1PIWB@1224|Proteobacteria,2U1JR@28211|Alphaproteobacteria 28211|Alphaproteobacteria K DNA-dependent RNA polymerase - - - - - - - - - - - - RNA_pol,RPOL_N k59_179204_1 1380394.JADL01000006_gene5263 2.03e-40 152.0 COG2268@1|root,COG2268@2|Bacteria,1NT13@1224|Proteobacteria,2U335@28211|Alphaproteobacteria,2JXVD@204441|Rhodospirillales 204441|Rhodospirillales S Band 7 protein - - - - - - - - - - - - - k59_204359_1 395492.Rleg2_0413 3.58e-14 75.1 COG1861@1|root,COG1861@2|Bacteria,1RG42@1224|Proteobacteria,2UABZ@28211|Alphaproteobacteria,4BEAT@82115|Rhizobiaceae 28211|Alphaproteobacteria M Cytidylyltransferase - - - ko:K07257 - - - - ko00000 - - - CTP_transf_3 k59_121675_1 1054968.G0X4X0_9CAUD 4.97e-08 52.0 4QB07@10239|Viruses,4QVI0@35237|dsDNA viruses no RNA stage,4QQSI@28883|Caudovirales,4QNMQ@10744|Podoviridae 10744|Podoviridae S Protein of unknown function (DUF2493) - - - - - - - - - - - - - k59_62360_1 1461694.ATO9_03930 2.44e-14 72.4 2CJKM@1|root,314EI@2|Bacteria,1RGVN@1224|Proteobacteria,2UBK7@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_244844_1 3055.EDP00743 2.31e-23 95.9 COG0740@1|root,KOG0840@2759|Eukaryota,37J0P@33090|Viridiplantae,34HP5@3041|Chlorophyta 3041|Chlorophyta O ATP-dependent Clp protease, proteolytic subunit - - 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease k59_244844_2 1528098.NOVO_02330 2.75e-79 251.0 COG0208@1|root,COG0208@2|Bacteria,1MWUS@1224|Proteobacteria,2TS3X@28211|Alphaproteobacteria,47ETF@766|Rickettsiales 766|Rickettsiales F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdB - 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_sm k59_244844_3 1898060.A0A1B2RW72_9VIRU 1.79e-18 88.2 4QAXQ@10239|Viruses 10239|Viruses S Ribonucleotide reductase, barrel domain - GO:0001959,GO:0001960,GO:0003674,GO:0003824,GO:0004748,GO:0005575,GO:0008150,GO:0008152,GO:0009966,GO:0009968,GO:0010646,GO:0010648,GO:0010803,GO:0010804,GO:0016491,GO:0016725,GO:0016728,GO:0018995,GO:0023051,GO:0023057,GO:0030430,GO:0033643,GO:0033646,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0055114,GO:0060759,GO:0060761,GO:0061731,GO:0065007 - - - - - - - - - - - k59_187687_2 69279.BG36_24180 3.32e-13 74.7 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2TQZE@28211|Alphaproteobacteria,43J93@69277|Phyllobacteriaceae 28211|Alphaproteobacteria M membrane MA20_30780 - - - - - - - - - - - Peptidase_M23 k59_87815_5 1165094.RINTHH_3920 1.15e-70 227.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_163420_1 145579.CAPSD_BPPHM 2.2e-23 102.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_223301_2 1609634.A0A0C5AFV4_9VIRU 2.93e-52 187.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_230182_1 1114970.PSF113_4313 1.5e-72 257.0 COG4643@1|root,COG5545@1|root,COG4643@2|Bacteria,COG5545@2|Bacteria,1MVGK@1224|Proteobacteria,1S6W2@1236|Gammaproteobacteria,1YSKX@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria S Virulence-associated protein E - - - ko:K06919 - - - - ko00000 - - - Prim-Pol,Toprim_3,Toprim_4,VirE k59_230182_6 985762.SAGN_11317 1.46e-12 65.9 2E3FM@1|root,32YEF@2|Bacteria,1VF4E@1239|Firmicutes,4IRKE@91061|Bacilli 91061|Bacilli S VRR-NUC domain - - - - - - - - - - - - VRR_NUC k59_230182_7 1114964.L485_00905 7.91e-101 317.0 COG1061@1|root,COG1061@2|Bacteria,1MV9F@1224|Proteobacteria,2TUXC@28211|Alphaproteobacteria,2K4Z7@204457|Sphingomonadales 204457|Sphingomonadales KL helicase superfamily c-terminal domain - - - - - - - - - - - - Helicase_C,ResIII k59_230182_8 716928.AJQT01000026_gene1833 2.18e-19 89.4 COG1074@1|root,COG1074@2|Bacteria,1PNWW@1224|Proteobacteria,2V1FZ@28211|Alphaproteobacteria,4BJ4A@82115|Rhizobiaceae 28211|Alphaproteobacteria L PDDEXK-like domain of unknown function (DUF3799) - - - - - - - - - - - - DUF3799 k59_114872_1 1385658.U5KNR1_9VIRU 1.61e-72 231.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_172765_1 562742.F4YXM9_9CAUD 1.6e-21 95.9 4QAQV@10239|Viruses,4QUPK@35237|dsDNA viruses no RNA stage,4QPCB@28883|Caudovirales,4QKM5@10699|Siphoviridae 10699|Siphoviridae S sequence-specific DNA binding - - - - - - - - - - - - - k59_163425_1 365048.Q0H278_9CAUD 0.000452 42.7 4QAX8@10239|Viruses,4QVB1@35237|dsDNA viruses no RNA stage,4QPHH@28883|Caudovirales 28883|Caudovirales S calcium ion binding - - - - - - - - - - - - - k59_7356_1 1082931.KKY_297 7.54e-43 157.0 COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,2TQWC@28211|Alphaproteobacteria,3N7JI@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria L PIF1-like helicase recD - 3.1.11.5 ko:K01144 - - - - ko00000,ko01000 - - - AAA_30,UvrD_C_2 k59_180391_2 243159.AFE_1301 6.86e-82 255.0 COG0175@1|root,COG0175@2|Bacteria,1R55Q@1224|Proteobacteria,1RY1Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria EH Phosphoadenosine phosphosulfate reductase family - - - - - - - - - - - - PAPS_reduct k59_139490_1 716928.AJQT01000006_gene2795 7.14e-21 90.5 COG0791@1|root,COG0791@2|Bacteria,1N19W@1224|Proteobacteria,2UD6N@28211|Alphaproteobacteria,4BMUC@82115|Rhizobiaceae 28211|Alphaproteobacteria M NLP P60 protein - - - - - - - - - - - - - k59_223318_1 118166.JH976538_gene5499 3.89e-10 65.9 COG5362@1|root,COG5362@2|Bacteria,1G727@1117|Cyanobacteria 1117|Cyanobacteria S TIGRFAM Phage - - - - - - - - - - - - - k59_263514_1 314345.SPV1_02692 2.71e-31 126.0 COG5164@1|root,COG5164@2|Bacteria,1N2ZN@1224|Proteobacteria 1224|Proteobacteria K regulation of DNA-templated transcription, elongation - - - - - - - - - - - - Collagen k59_215629_2 1123519.PSJM300_14835 1.31e-42 160.0 COG0464@1|root,COG0464@2|Bacteria,1QU82@1224|Proteobacteria,1SA9J@1236|Gammaproteobacteria,1Z2EZ@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria O Zonular occludens toxin (Zot) - - - - - - - - - - - - Zot k59_149289_1 1331060.RLDS_03865 9.81e-54 176.0 2CMPB@1|root,32SF8@2|Bacteria,1RCNY@1224|Proteobacteria,2UPH0@28211|Alphaproteobacteria,2K2QJ@204457|Sphingomonadales 204457|Sphingomonadales S Transcription elongation protein SprT - - - - - - - - - - - - - k59_150141_1 1408428.JNJP01000079_gene3370 4.17e-05 49.7 2E57E@1|root,32ZZZ@2|Bacteria,1NATW@1224|Proteobacteria,436CJ@68525|delta/epsilon subdivisions,2X0XN@28221|Deltaproteobacteria,2MDQD@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_125317_1 1500301.JQMF01000006_gene1760 1.92e-108 333.0 COG0749@1|root,COG0749@2|Bacteria,1P27P@1224|Proteobacteria,2TVEI@28211|Alphaproteobacteria,4BIH2@82115|Rhizobiaceae 28211|Alphaproteobacteria L DNA polymerase A domain - - - - - - - - - - - - DNA_pol_A k59_183254_1 1385658.U5KPZ6_9VIRU 1.5e-106 326.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_141876_2 907931.AEIZ01000007_gene672 1.35e-11 68.9 COG3774@1|root,COG3774@2|Bacteria,1V3YG@1239|Firmicutes,4HXBN@91061|Bacilli,4AYJW@81850|Leuconostocaceae 91061|Bacilli M Glycosyltransferase sugar-binding region containing DXD motif - - - - - - - - - - - - Gly_transf_sug k59_75490_2 1179778.PMM47T1_13835 2.16e-10 73.6 2DPZ4@1|root,32UN5@2|Bacteria,1R0ZA@1224|Proteobacteria,1S69M@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_100301_2 1041147.AUFB01000009_gene1861 5.41e-20 99.4 2F5UF@1|root,33YDD@2|Bacteria,1PH7C@1224|Proteobacteria,2V8WS@28211|Alphaproteobacteria,4BKM2@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_100301_3 639283.Snov_0721 9.81e-25 108.0 COG4733@1|root,COG4733@2|Bacteria 2|Bacteria S cellulase activity - - - ko:K20276 ko02024,map02024 - - - ko00000,ko00001 - - - Big_3_5,Big_5,fn3 k59_937_1 103807.Q9MBZ3_9CAUD 1.54e-18 82.4 4QHC8@10239|Viruses,4QZ9A@35237|dsDNA viruses no RNA stage,4QSRC@28883|Caudovirales,4QKFD@10662|Myoviridae 10662|Myoviridae S D-alanyl-D-alanine carboxypeptidase - - - - - - - - - - - - - k59_92101_2 1453501.JELR01000001_gene2546 3.36e-12 64.3 2EIQ2@1|root,33CFI@2|Bacteria,1NHAI@1224|Proteobacteria,1SSQC@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_249574_1 580332.Slit_1922 8.05e-81 265.0 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1NKZK@1224|Proteobacteria,2VM59@28216|Betaproteobacteria 28216|Betaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_199875_1 1417296.U879_03920 1.15e-07 59.7 COG5525@1|root,COG5525@2|Bacteria,1MVS3@1224|Proteobacteria,2TRW8@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Terminase - - - - - - - - - - - - Terminase_GpA k59_258186_1 1234888.K0A2J2_9VIRU 2.08e-35 135.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_42431_2 931276.Cspa_c39570 4.76e-28 110.0 COG4186@1|root,COG4186@2|Bacteria,1V9R4@1239|Firmicutes,25CCX@186801|Clostridia 186801|Clostridia S Ser Thr phosphatase family protein - - - - - - - - - - - - - k59_150299_1 1692246.A0A0K1RLM8_9CIRC 3.35e-14 73.9 4QBFZ@10239|Viruses,4QUKU@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_258187_1 1366050.N234_18785 3.62e-18 84.7 2D0K9@1|root,32T8S@2|Bacteria,1MZRW@1224|Proteobacteria,2VW7X@28216|Betaproteobacteria,1KE19@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_1113_1 1137799.GZ78_10995 2.01e-21 89.7 2AD08@1|root,312N7@2|Bacteria,1NDC4@1224|Proteobacteria,1SAPT@1236|Gammaproteobacteria,1XQHK@135619|Oceanospirillales 135619|Oceanospirillales S Holin of 3TMs, for gene-transfer release - - - - - - - - - - - - GTA_holin_3TM k59_142014_7 1346791.M529_02355 5.66e-37 140.0 COG0175@1|root,COG0175@2|Bacteria,1QZJ1@1224|Proteobacteria,2U233@28211|Alphaproteobacteria 28211|Alphaproteobacteria EH sulfate reduction - - - - - - - - - - - - - k59_118440_1 497321.C664_00395 1.58e-44 161.0 COG0464@1|root,COG0464@2|Bacteria,1QU82@1224|Proteobacteria,2WHSD@28216|Betaproteobacteria,2KW8F@206389|Rhodocyclales 206389|Rhodocyclales O Zonular occludens toxin (Zot) - - - - - - - - - - - - Zot k59_2274_2 1618259.A0A0C5I2B5_9CIRC 1.84e-92 283.0 4QE84@10239|Viruses,4QUKR@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_184251_1 1618247.A0A0C5I2K0_9CIRC 6.34e-17 82.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_143237_1 1234888.K0A2J2_9VIRU 4.39e-29 119.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_151459_1 1458863.A0A088C4H0_9CAUD 3.69e-09 60.1 4QAX8@10239|Viruses,4QVB1@35237|dsDNA viruses no RNA stage,4QPHH@28883|Caudovirales 28883|Caudovirales S calcium ion binding - - - - - - - - - - - - - k59_118448_1 742740.HMPREF9474_02303 3.34e-96 320.0 2EWZQ@1|root,33QB0@2|Bacteria,1V0T1@1239|Firmicutes,249Z2@186801|Clostridia,221YV@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_10021_1 1229761.K4HZA5_9CAUD 1.85e-27 119.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QII1@10662|Myoviridae 10662|Myoviridae S N-methyltransferase activity - - - - - - - - - - - - - k59_126654_1 1692242.A0A0K1RL37_9CIRC 1.41e-58 194.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_51843_1 1234888.K0A2J2_9VIRU 9.58e-70 231.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_18076_3 1034115.G1D5L0_9CAUD 3.47e-18 83.2 4QCF5@10239|Viruses,4QV2A@35237|dsDNA viruses no RNA stage,4QPJI@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_2281_2 1110502.TMO_0047 2.85e-15 79.3 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,2TVGJ@28211|Alphaproteobacteria,2JPR0@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - k59_93182_1 2003327.CAPSD_BPCHP 6.23e-24 105.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_242413_1 1379708.S5SYC3_9CIRC 3.49e-27 110.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_76815_2 1121106.JQKB01000013_gene5433 2.02e-07 59.7 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,2TVGJ@28211|Alphaproteobacteria,2JPR0@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - k59_201056_5 2003327.CAPSD_BPCHP 1.22e-23 112.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_102408_1 1986029.Q9MBM8_9VIRU 1.98e-41 150.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_251196_4 1166016.W5S_2328 2.95e-50 172.0 2CI0W@1|root,2Z81W@2|Bacteria,1R9FZ@1224|Proteobacteria,1S0NA@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage X family - - - - - - - - - - - - Phage_CRI,Phage_X k59_260255_2 1234888.K0A2J2_9VIRU 2.48e-51 180.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_19004_1 926564.KI911577_gene454 6.16e-43 160.0 COG0358@1|root,COG3378@1|root,COG0358@2|Bacteria,COG3378@2|Bacteria,2H1DT@201174|Actinobacteria 201174|Actinobacteria T Phage plasmid primase, P4 family - - - ko:K06919 - - - - ko00000 - - - D5_N,Pox_D5,Toprim_2 k59_135929_3 1234888.K0A2R8_9VIRU 1.37e-14 79.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_202072_1 1205680.CAKO01000024_gene4509 3.79e-33 134.0 2F26G@1|root,33V4S@2|Bacteria,1NUS1@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_219497_1 1385658.U5KPZ6_9VIRU 4.62e-126 381.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_219497_2 1609634.A0A0C5ANA6_9VIRU 9.49e-23 98.6 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_77848_2 1380346.JNIH01000064_gene5212 2.89e-06 53.9 COG5301@1|root,COG5301@2|Bacteria,2ISHQ@201174|Actinobacteria 201174|Actinobacteria G cellulose 1,4-beta-cellobiosidase activity - - - - - - - - - - - - - k59_19120_4 1219035.NT2_13_00580 3.36e-20 92.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_135938_1 665950.HMPREF1025_02007 2.26e-13 75.5 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_60683_4 118005.AWNK01000007_gene550 2.47e-05 53.5 COG0859@1|root,COG0859@2|Bacteria 2|Bacteria M ADP-heptose-lipopolysaccharide heptosyltransferase activity rfaF - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02527,ko:K02841,ko:K02843,ko:K12982 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763 RC00009,RC00077,RC00247 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT30,GT9 - Glyco_transf_9 k59_219501_1 1150626.PHAMO_290112 2.6e-74 256.0 28HCK@1|root,2Z7PE@2|Bacteria,1NK7S@1224|Proteobacteria,2TSMJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_36060_2 89187.ISM_07470 4.19e-18 86.3 COG0457@1|root,COG0457@2|Bacteria,1RF9I@1224|Proteobacteria,2U8A6@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Tetratricopeptide repeat - - - - - - - - - - - - - k59_12219_1 1028800.RG540_CH13740 7.12e-115 366.0 COG0749@1|root,COG0749@2|Bacteria,1P27P@1224|Proteobacteria,2TVEI@28211|Alphaproteobacteria,4BIH2@82115|Rhizobiaceae 28211|Alphaproteobacteria L DNA polymerase A domain - - - - - - - - - - - - DNA_pol_A k59_252479_1 388399.SSE37_18682 2.94e-20 98.2 COG0553@1|root,COG0553@2|Bacteria,1MV6M@1224|Proteobacteria,2TU4W@28211|Alphaproteobacteria 28211|Alphaproteobacteria L COG0553 Superfamily II DNA RNA helicases, SNF2 family - - - - - - - - - - - - Helicase_C,SNF2_N k59_5036_3 1171373.PACID_13800 4.9e-36 150.0 COG1061@1|root,COG1061@2|Bacteria,2GIU5@201174|Actinobacteria,4DP3W@85009|Propionibacteriales 201174|Actinobacteria L Type III restriction enzyme, res subunit sdrA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - ResIII k59_228338_5 1380894.S5TR92_9CIRC 5.64e-26 112.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_112574_2 759362.KVU_1651 2.54e-20 89.0 COG3179@1|root,COG3179@2|Bacteria,1R71F@1224|Proteobacteria,2UD1N@28211|Alphaproteobacteria 28211|Alphaproteobacteria S chitinase - - - - - - - - - - - - Glyco_hydro_19 k59_95005_2 1609634.A0A0C5ANA6_9VIRU 7.74e-21 93.6 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_252486_1 1121334.KB911068_gene2299 1.44e-05 55.5 COG5283@1|root,COG5412@1|root,COG5283@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,247QT@186801|Clostridia,3WJR8@541000|Ruminococcaceae 186801|Clostridia D Phage tail tape measure protein, TP901 family - - - - - - - - - - - - PhageMin_Tail k59_46107_2 1121441.AUCX01000031_gene1701 1.81e-43 147.0 2AFF0@1|root,315F0@2|Bacteria,1RHGE@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_5041_1 1121459.AQXE01000001_gene2753 1.22e-10 64.7 2DUXE@1|root,32UY2@2|Bacteria,1N2YI@1224|Proteobacteria,430A8@68525|delta/epsilon subdivisions,2WVIN@28221|Deltaproteobacteria,2MCZ8@213115|Desulfovibrionales 28221|Deltaproteobacteria S Phage T7 capsid assembly protein - - - - - - - - - - - - Phage_T7_Capsid k59_186755_1 1636270.A0A0E3JSB2_9CAUD 2.55e-08 58.9 4QBFN@10239|Viruses,4QPTW@28883|Caudovirales,4QNPZ@10744|Podoviridae 10744|Podoviridae S Phage stabilisation protein - - - - - - - - - - - - - k59_146110_1 1609634.A0A0C5AFV4_9VIRU 1.92e-39 144.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_235708_1 1051985.l11_04660 5.03e-11 59.7 2AFW0@1|root,315YT@2|Bacteria,1PWKT@1224|Proteobacteria,2WC55@28216|Betaproteobacteria,2KTIZ@206351|Neisseriales 206351|Neisseriales S Phage protein (N4 Gp49/phage Sf6 gene 66) family - - - - - - - - - - - - Phage_gp49_66 k59_204918_2 906669.G8C7P6_9CAUD 4.56e-13 71.2 4QBZR@10239|Viruses,4QX8Z@35237|dsDNA viruses no RNA stage,4QPDZ@28883|Caudovirales,4QMQP@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_72055_3 111781.Lepto7376_4587 2.17e-18 81.6 COG1525@1|root,COG1525@2|Bacteria 2|Bacteria L nuclease - - 3.1.31.1 ko:K01174 - - - - ko00000,ko01000 - - - Ada_Zn_binding,Excalibur,SNase k59_47693_2 145579.CAPSD_BPPHM 7.07e-55 199.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_162857_1 1618238.A0A0C5IB41_9CIRC 6.58e-12 70.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_138741_1 1121106.JQKB01000016_gene5268 3.17e-41 152.0 COG0500@1|root,COG2520@1|root,COG2226@2|Bacteria,COG2520@2|Bacteria,1RIYU@1224|Proteobacteria,2U2ZF@28211|Alphaproteobacteria,2JSTB@204441|Rhodospirillales 204441|Rhodospirillales Q Methyltransferase FkbM domain - - - - - - - - - - - - Methyltransf_21 k59_72072_1 187303.BN69_2082 4.06e-78 247.0 COG0673@1|root,COG0673@2|Bacteria 2|Bacteria S inositol 2-dehydrogenase activity - - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - GFO_IDH_MocA,GFO_IDH_MocA_C k59_72072_2 402777.KB235904_gene3432 8.16e-15 73.2 COG0500@1|root,COG2226@2|Bacteria,1G5BT@1117|Cyanobacteria 1117|Cyanobacteria Q ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_31 k59_13290_2 1038860.AXAP01000015_gene2003 2.71e-10 65.1 COG3740@1|root,COG3740@2|Bacteria,1QVIJ@1224|Proteobacteria,2TVIM@28211|Alphaproteobacteria,3K0XM@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Caudovirus prohead serine protease - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_188621_1 742767.HMPREF9456_03415 5.15e-12 65.9 2DQVJ@1|root,338XS@2|Bacteria,4NWR7@976|Bacteroidetes,2FUTX@200643|Bacteroidia,2315D@171551|Porphyromonadaceae 976|Bacteroidetes - - - - - - - - - - - - - - - k59_55818_2 1234888.K0A2J2_9VIRU 2.78e-92 287.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_238022_1 1123314.AUIO01000005_gene168 5.73e-10 68.2 28MKK@1|root,2ZAWR@2|Bacteria,1UYAT@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - RNA_helicase,Viral_Rep k59_115654_1 710393.HSUHS1_0672 2.88e-24 105.0 COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,42M69@68525|delta/epsilon subdivisions,2YN4V@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA k59_22901_1 1156844.KB891809_gene7935 5.24e-14 81.6 COG0791@1|root,COG3409@1|root,COG0791@2|Bacteria,COG3409@2|Bacteria,2I61A@201174|Actinobacteria 201174|Actinobacteria M Peptidoglycan-binding domain 1 protein - - - - - - - - - - - - NLPC_P60,PG_binding_1 k59_149199_1 1476973.JMMB01000007_gene2168 2.8e-11 69.7 COG0305@1|root,COG0305@2|Bacteria,1VTC0@1239|Firmicutes,24XTJ@186801|Clostridia,25SWT@186804|Peptostreptococcaceae 186801|Clostridia L DnaB-like helicase N terminal domain - - - - - - - - - - - - DnaB,DnaB_C k59_173718_1 797304.Natgr_1861 1.69e-35 143.0 COG1196@1|root,arCOG00371@2157|Archaea 2157|Archaea D Required for chromosome condensation and partitioning - - 3.6.4.12 ko:K03658 - - - - ko00000,ko01000,ko03400 - - - - k59_190300_4 1205683.CAKR01000001_gene2100 5.59e-21 98.2 2DBI5@1|root,2Z9EN@2|Bacteria,1PMHG@1224|Proteobacteria,1RQE1@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Exodeoxyribonuclease VIII - - - ko:K10906 - - - - ko00000,ko01000,ko03400 - - - DUF3799 k59_264383_1 105422.BBPM01000058_gene4616 3.35e-47 169.0 COG1475@1|root,COG4422@1|root,COG1475@2|Bacteria,COG4422@2|Bacteria,2IAY7@201174|Actinobacteria,2NK47@228398|Streptacidiphilus 201174|Actinobacteria K DNA binding - - - - - - - - - - - - ParBc k59_14646_1 1380394.JADL01000008_gene3768 2.69e-14 77.8 COG3064@1|root,COG3064@2|Bacteria,1R6JV@1224|Proteobacteria,2U5NE@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Membrane - - - - - - - - - - - - - k59_14646_2 488538.SAR116_0377 8.13e-228 645.0 COG4373@1|root,COG4373@2|Bacteria 2|Bacteria - - gp17a - - ko:K06909 - - - - ko00000 - - - Terminase_6,Terminase_6C k59_49522_2 1165094.RINTHH_3920 1e-57 192.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_22931_2 691965.D4P7C5_9CAUD 2.78e-82 260.0 4QBV3@10239|Viruses,4QW0W@35237|dsDNA viruses no RNA stage,4QPPJ@28883|Caudovirales,4QKW5@10699|Siphoviridae 10699|Siphoviridae S Phage Terminase - - - - - - - - - - - - - k59_198683_1 1051675.G0YQH7_9CAUD 1.41e-170 489.0 4QGGR@10239|Viruses,4QZHR@35237|dsDNA viruses no RNA stage,4QUGZ@28883|Caudovirales,4QNY3@10744|Podoviridae 10744|Podoviridae S viral capsid - - - - - - - - - - - - - k59_265015_2 1692242.A0A0K1RL37_9CIRC 9.22e-79 248.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_239911_3 1121861.KB899915_gene1863 8.22e-96 314.0 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,2TVGJ@28211|Alphaproteobacteria,2JPR0@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - k59_215022_2 1692246.A0A0K1RLM8_9CIRC 3.52e-09 61.2 4QBFZ@10239|Viruses,4QUKU@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_16332_2 401526.TcarDRAFT_1284 2.39e-08 65.9 COG3170@1|root,COG3170@2|Bacteria,1U52E@1239|Firmicutes,4H6S0@909932|Negativicutes 909932|Negativicutes NU Tfp pilus assembly protein FimV - - - - - - - - - - - - - k59_65617_1 1986029.Q9MBM8_9VIRU 2.72e-05 45.4 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_65930_2 349102.Rsph17025_0444 2.34e-76 270.0 28IJ1@1|root,2Z8K0@2|Bacteria,1R5PC@1224|Proteobacteria,2U0RA@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_265074_4 1000565.METUNv1_03731 4.54e-59 202.0 COG0464@1|root,COG0464@2|Bacteria,1QU82@1224|Proteobacteria,2WHSD@28216|Betaproteobacteria,2KW8F@206389|Rhodocyclales 206389|Rhodocyclales O Zonular occludens toxin (Zot) - - - - - - - - - - - - Zot k59_265075_1 1692252.A0A0K1RL35_9CIRC 8.92e-40 143.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_265075_3 1692252.A0A0K1RL35_9CIRC 1.13e-45 158.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_240229_1 232346.JHQL01000009_gene2032 4.25e-55 189.0 2D784@1|root,32TNH@2|Bacteria,1N098@1224|Proteobacteria,1SDM3@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_257508_1 928724.SacglDRAFT_02350 0.00021 52.4 COG1961@1|root,COG1961@2|Bacteria,2I8IZ@201174|Actinobacteria,4E6C2@85010|Pseudonocardiales 201174|Actinobacteria L Resolvase, N terminal domain - - - - - - - - - - - - Recombinase,Resolvase,Zn_ribbon_recom k59_33608_1 1121935.AQXX01000123_gene247 4.78e-11 61.2 2AD08@1|root,312N7@2|Bacteria,1NDC4@1224|Proteobacteria,1SAPT@1236|Gammaproteobacteria,1XQHK@135619|Oceanospirillales 135619|Oceanospirillales S Holin of 3TMs, for gene-transfer release - - - - - - - - - - - - GTA_holin_3TM k59_25377_1 762982.HMPREF9442_01223 3.15e-20 93.2 COG0270@1|root,COG0270@2|Bacteria,4NJPP@976|Bacteroidetes,2FKYT@200643|Bacteroidia 976|Bacteroidetes H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_199425_1 1385658.U5KPZ6_9VIRU 1.55e-157 462.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_33609_1 749222.Nitsa_1386 3.22e-05 52.8 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2YMQV@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_41904_2 402612.FP2177 2.55e-39 147.0 COG0714@1|root,COG0714@2|Bacteria,4NJMT@976|Bacteroidetes,1HZMP@117743|Flavobacteriia 976|Bacteroidetes S AAA domain (dynein-related subfamily) - - 6.6.1.2 ko:K09882 ko00860,ko01100,map00860,map01100 - R05227 RC02000 ko00000,ko00001,ko01000 - - - AAA_5 k59_166194_2 1197951.I6R0Z0_9CAUD 5.56e-43 155.0 4QGZN@10239|Viruses,4R0FF@35237|dsDNA viruses no RNA stage,4QTUK@28883|Caudovirales 28883|Caudovirales S nuclease activity - - - - - - - - - - - - - k59_232624_1 1000565.METUNv1_01209 2.85e-10 62.0 2D784@1|root,32TNH@2|Bacteria,1N098@1224|Proteobacteria,2VX0M@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_42024_1 365046.Rta_33120 0.000465 43.9 COG3405@1|root,COG3405@2|Bacteria,1QZE5@1224|Proteobacteria,2W62R@28216|Betaproteobacteria,4AIQV@80864|Comamonadaceae 28216|Betaproteobacteria G Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - - - - - - - - - - - k59_33681_1 1986029.Q9MBM8_9VIRU 1.03e-44 159.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_33681_3 1165094.RINTHH_3920 5.13e-68 221.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_191157_1 370438.PTH_2456 7.49e-23 99.4 COG4227@1|root,COG4227@2|Bacteria,1TQN4@1239|Firmicutes,2482H@186801|Clostridia,2616R@186807|Peptococcaceae 186801|Clostridia L Psort location Cytoplasmic, score - - - - - - - - - - - - - k59_108280_1 145579.REP_BPPHM 1.14e-34 134.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_108280_3 105154.Q9MBU6_9VIRU 2.46e-231 655.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_108280_5 1986029.Q9MBM6_9VIRU 3.14e-19 86.3 4QDBB@10239|Viruses,4QUM0@29258|ssDNA viruses,4QP4D@10841|Microviridae 10841|Microviridae S Chlamydia-phage Chp2 scaffold (Chlamy_scaf) - - - - - - - - - - - - - k59_224390_1 1121441.AUCX01000014_gene511 7.78e-33 125.0 28MVD@1|root,2ZB2Y@2|Bacteria,1R8NK@1224|Proteobacteria,42QIP@68525|delta/epsilon subdivisions,2WKTY@28221|Deltaproteobacteria,2MA65@213115|Desulfovibrionales 28221|Deltaproteobacteria S Protein of unknown function (DUF4043) - - - - - - - - - - - - DUF4043 k59_8824_1 1234888.K0A2J2_9VIRU 1.89e-68 224.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_199507_1 1197951.I6S6K3_9CAUD 5.66e-12 75.9 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales 28883|Caudovirales S N-acetylmuramoyl-L-alanine amidase activity - - - - - - - - - - - - - k59_58511_2 1609634.A0A0C5ANA6_9VIRU 9.61e-20 90.9 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_116583_1 1385658.U5KPZ6_9VIRU 1.67e-40 149.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_233175_2 888832.HMPREF9420_1956 7.02e-10 68.2 COG5283@1|root,COG5283@2|Bacteria,4NIZH@976|Bacteroidetes,2G14D@200643|Bacteroidia 976|Bacteroidetes D domain protein - - - - - - - - - - - - PhageMin_Tail k59_67434_5 1234888.K0A2J2_9VIRU 6.18e-32 123.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_26154_2 1692249.A0A0K1RLN8_9CIRC 4.63e-50 169.0 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_50873_8 1235835.C814_01159 8.72e-31 131.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,3WGFC@541000|Ruminococcaceae 186801|Clostridia KL SNF2 family - - - - - - - - - - - - Helicase_C,SNF2_N,SNF2_assoc,SWIM k59_50873_16 326297.Sama_0093 6.25e-39 162.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,2Q9N3@267890|Shewanellaceae 1236|Gammaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_50873_22 1458697.W6E8P3_9CAUD 1.15e-07 63.2 4QB9Y@10239|Viruses,4QWGZ@35237|dsDNA viruses no RNA stage,4QPTT@28883|Caudovirales,4QKUM@10699|Siphoviridae 10699|Siphoviridae S hydrolase activity, acting on acid anhydrides - - - - - - - - - - - - - k59_92378_1 913970.F8RW82_9VIRU 8.06e-62 219.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_42621_1 691965.D4P7E6_9CAUD 1.82e-11 71.6 4QAK6@10239|Viruses,4R01K@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_117257_2 1196028.ALEF01000043_gene479 3.72e-34 124.0 COG0863@1|root,COG0863@2|Bacteria,1V0ZF@1239|Firmicutes,4HCF9@91061|Bacilli,4C694@84406|Virgibacillus 91061|Bacilli L DNA methylase - - - - - - - - - - - - N6_N4_Mtase k59_50998_1 1477404.A0A023NI07_9CAUD 1.93e-28 114.0 4QF3C@10239|Viruses,4QWIA@35237|dsDNA viruses no RNA stage,4QU4U@28883|Caudovirales,4QNNQ@10744|Podoviridae 10744|Podoviridae S host cell wall - - - - - - - - - - - - - k59_51871_1 1618247.A0A0C5IMK7_9CIRC 0.000258 49.3 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_27142_9 1451189.CFAL_11900 8.64e-26 108.0 COG2887@1|root,COG2887@2|Bacteria,2IBBB@201174|Actinobacteria,22K0W@1653|Corynebacteriaceae 201174|Actinobacteria L Protein of unknown function (DUF2800) - - - - - - - - - - - - DUF2800 k59_35129_1 645099.MREP_BBTVA 4.07e-14 77.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_175982_1 1157635.KB892046_gene5781 1.56e-18 84.3 COG0073@1|root,COG0073@2|Bacteria,2IMWW@201174|Actinobacteria 201174|Actinobacteria J RNA ligase - - - - - - - - - - - - RNA_ligase k59_27286_1 1233488.S4T7Z9_9CAUD 3.11e-71 242.0 4QG3G@10239|Viruses,4R03C@35237|dsDNA viruses no RNA stage,4QPZ8@28883|Caudovirales,4QNW8@10744|Podoviridae 10744|Podoviridae S catalytic activity - - - - - - - - - - - - - k59_250511_8 288000.BBta_5776 1.29e-16 76.3 2CC8P@1|root,2ZI81@2|Bacteria,1N10A@1224|Proteobacteria,2UD9A@28211|Alphaproteobacteria,3K0MK@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_250511_9 1094557.ME3_00393 4.75e-54 196.0 2CC8M@1|root,308VJ@2|Bacteria,1R789@1224|Proteobacteria,2U2NB@28211|Alphaproteobacteria,48T5T@772|Bartonellaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_250511_12 1524880.A0A076GC93_9VIRU 3.48e-43 159.0 4QAK6@10239|Viruses 10239|Viruses S N-acetylmuramoyl-L-alanine amidase activity - - - - - - - - - - - - - k59_250511_13 883156.HMPREF9282_00554 1.29e-06 58.2 2EVCH@1|root,33NSZ@2|Bacteria,1W370@1239|Firmicutes,4H8MI@909932|Negativicutes 909932|Negativicutes - - - - - - - - - - - - - - - k59_250511_15 392499.Swit_2199 2.18e-54 184.0 COG0338@1|root,COG0338@2|Bacteria,1P85S@1224|Proteobacteria,2TS2X@28211|Alphaproteobacteria,2K2FK@204457|Sphingomonadales 204457|Sphingomonadales L D12 class N6 adenine-specific DNA methyltransferase - - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 k59_250511_20 1517681.HW45_18920 2.27e-71 230.0 COG4227@1|root,COG4227@2|Bacteria,1MU8I@1224|Proteobacteria,1RNU7@1236|Gammaproteobacteria,1XVNE@135623|Vibrionales 135623|Vibrionales L Domain of unknown function (DUF1738) - - - - - - - - - - - - DUF1738 k59_250511_29 1380394.JADL01000008_gene3768 3.5e-92 309.0 COG3064@1|root,COG3064@2|Bacteria,1R6JV@1224|Proteobacteria,2U5NE@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Membrane - - - - - - - - - - - - - k59_250511_36 663241.C9E2I7_9CAUD 1.25e-38 151.0 4QFE9@10239|Viruses,4QYP9@35237|dsDNA viruses no RNA stage,4QQZT@28883|Caudovirales,4QMZ7@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_177078_2 1381123.AYOD01000034_gene3815 1.85e-08 61.6 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2TRJF@28211|Alphaproteobacteria,43GS4@69277|Phyllobacteriaceae 28211|Alphaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_119482_1 1234888.K0A2J2_9VIRU 2.12e-53 183.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_219487_1 1414739.W6ATE0_9CAUD 9.3e-93 293.0 4QHNU@10239|Viruses,4QQZH@28883|Caudovirales,4QKRG@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_60680_2 1618247.A0A0C5IMK7_9CIRC 1.32e-11 68.6 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_53127_1 1609634.A0A0C5AFT2_9VIRU 1.2e-81 254.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_53127_4 1609634.A0A0C5AFV4_9VIRU 7.15e-11 62.4 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_93977_1 1385658.U5KPZ6_9VIRU 5.34e-107 328.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_234644_1 156889.Mmc1_1716 1.47e-14 81.6 28NGF@1|root,2ZBII@2|Bacteria,1R9KY@1224|Proteobacteria,2U1P7@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_10938_1 691965.D4P7E6_9CAUD 1.06e-11 72.8 4QAK6@10239|Viruses,4R01K@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_53131_2 41431.PCC8801_1016 1.99e-44 157.0 COG0592@1|root,COG0592@2|Bacteria,1FZV5@1117|Cyanobacteria,3KH2G@43988|Cyanothece 1117|Cyanobacteria L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 k59_209877_1 44454.NF84_14185 1.37e-15 81.3 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2GJY2@201174|Actinobacteria,2338A@1762|Mycobacteriaceae 201174|Actinobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_85267_1 547045.NEISICOT_01400 2.18e-55 186.0 COG4653@1|root,COG4653@2|Bacteria,1MWMB@1224|Proteobacteria,2VN8K@28216|Betaproteobacteria 28216|Betaproteobacteria S Phage capsid family - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_102550_1 105154.Q9MBU0_9VIRU 6.62e-44 157.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_102550_2 1609634.A0A0C5ANA6_9VIRU 2.38e-07 57.0 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_102550_3 1385658.U5KPZ6_9VIRU 1.38e-65 215.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_127919_1 1385658.U5KPZ6_9VIRU 7.63e-98 303.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_193368_1 1416009.V9VCT7_9CAUD 3.61e-34 132.0 4QFP7@10239|Viruses,4QWTW@35237|dsDNA viruses no RNA stage,4QSRU@28883|Caudovirales,4QNWE@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - - - - - - - - - - - - - k59_243408_3 1609634.A0A0C5AFV4_9VIRU 1.11e-148 438.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_203400_1 762550.LEGAS_1589 4.05e-05 52.0 COG2369@1|root,COG2369@2|Bacteria,1U6KJ@1239|Firmicutes,4HFY6@91061|Bacilli,4AY7G@81850|Leuconostocaceae 91061|Bacilli S Phage Mu protein F like protein - - - - - - - - - - - - ADPrib_exo_Tox,Ntox50,Phage_Mu_F k59_145971_2 1182590.BN5_01565 1.34e-92 282.0 COG0175@1|root,COG0175@2|Bacteria,1PZ96@1224|Proteobacteria,1TC80@1236|Gammaproteobacteria,1YK10@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria EH 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase and related enzymes - - - - - - - - - - - - - k59_178310_1 1609634.A0A0C5AFT2_9VIRU 1.76e-35 133.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_12132_1 1609634.A0A0C5AFV4_9VIRU 2.97e-16 78.6 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_129345_1 1609634.A0A0C5AFV4_9VIRU 2.99e-86 275.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_194340_1 871968.DESME_08930 3.59e-27 119.0 2E2CM@1|root,32XHK@2|Bacteria,1VCFP@1239|Firmicutes,24Q3M@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_194511_1 1121468.AUBR01000007_gene299 2.57e-11 68.2 COG0863@1|root,COG0863@2|Bacteria,1TR56@1239|Firmicutes,248NR@186801|Clostridia 186801|Clostridia L Belongs to the N(4) N(6)-methyltransferase family cfr9IM - 2.1.1.113 ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_137345_1 1280949.HAD_00465 1.82e-40 148.0 COG0208@1|root,COG0208@2|Bacteria,1MWUS@1224|Proteobacteria,2TS3X@28211|Alphaproteobacteria,43WU8@69657|Hyphomonadaceae 28211|Alphaproteobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdF - 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_sm k59_137345_2 398720.MED217_17130 9.26e-31 125.0 COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,1HXHB@117743|Flavobacteriia,2XJHM@283735|Leeuwenhoekiella 976|Bacteroidetes F Ribonucleotide reductase, barrel domain nrdA - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_lgC,Ribonuc_red_lgN k59_37157_1 652103.Rpdx1_2519 9.09e-58 202.0 COG1783@1|root,COG1783@2|Bacteria,1MVJB@1224|Proteobacteria,2U2BM@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6 k59_79919_3 572547.Amico_0476 1.33e-06 52.8 2DPDE@1|root,331KH@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_13208_1 631362.Thi970DRAFT_04121 6.36e-07 55.5 COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,1RMS8@1236|Gammaproteobacteria,1WX5E@135613|Chromatiales 135613|Chromatiales M PFAM Lytic - - - ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 - SLT,SLT_L k59_6442_2 1476876.JOJO01000002_gene6633 7.31e-55 199.0 2B5CX@1|root,31Y73@2|Bacteria,2H0BC@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_96029_1 399795.CtesDRAFT_PD0612 0.000745 50.1 COG3209@1|root,COG3210@1|root,COG4675@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,COG4675@2|Bacteria,1RJRG@1224|Proteobacteria,2WEZQ@28216|Betaproteobacteria 28216|Betaproteobacteria M COG3209 Rhs family protein - - - - - - - - - - - - - k59_222493_1 521674.Plim_4263 2.34e-62 210.0 COG3941@1|root,COG5412@1|root,COG3941@2|Bacteria,COG5412@2|Bacteria,2J3JW@203682|Planctomycetes 203682|Planctomycetes S phage tail tape measure protein - - - - - - - - - - - - - k59_96034_1 1414737.V9QJG5_9CAUD 8.63e-10 65.1 4QGMJ@10239|Viruses,4QX02@35237|dsDNA viruses no RNA stage,4QSYG@28883|Caudovirales,4QM5B@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_31000_2 1262513.K7Z9S9_9CAUD 1e-55 185.0 4QAKW@10239|Viruses,4QX74@35237|dsDNA viruses no RNA stage,4QPSV@28883|Caudovirales,4QI33@10662|Myoviridae 10662|Myoviridae - - - GO:0005575,GO:0019012,GO:0044423,GO:0098015,GO:0098025 - - - - - - - - - - - k59_32159_7 1115512.EH105704_01_01570 9.25e-64 206.0 COG0175@1|root,COG0175@2|Bacteria,1PA2H@1224|Proteobacteria,1S0DB@1236|Gammaproteobacteria 1236|Gammaproteobacteria EH Phosphoadenosine phosphosulfate reductase family - - - - - - - - - - - - PAPS_reduct k59_148655_1 1385658.U5KPZ6_9VIRU 2.46e-70 231.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_180713_3 420324.KI911961_gene1745 1.42e-15 79.0 2CK39@1|root,32SBG@2|Bacteria,1MZ6F@1224|Proteobacteria,2UBT5@28211|Alphaproteobacteria,1JR6I@119045|Methylobacteriaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - Phage_connect_1 k59_56616_1 105154.Q9MBU6_9VIRU 5.21e-80 255.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_96935_1 105154.Q9MBU6_9VIRU 1.16e-171 503.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_206009_2 1385658.U5KPZ6_9VIRU 8.47e-37 138.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_206102_2 1177928.TH2_05253 1.69e-07 61.2 COG1511@1|root,COG3941@1|root,COG1511@2|Bacteria,COG3941@2|Bacteria 2|Bacteria O tape measure - - - - - - - - - - - - DUF4175,TMP_2,Tape_meas_lam_C k59_148769_1 1314.HKU360_01215 4.06e-29 124.0 COG5283@1|root,COG5283@2|Bacteria,1UHQM@1239|Firmicutes,4HEHJ@91061|Bacilli 91061|Bacilli D Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_156431_1 1574422.A0A0A1ENW9_9CIRC 4.25e-64 211.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_57350_21 1085623.GNIT_0964 1.65e-06 48.5 2DNTG@1|root,32Z26@2|Bacteria,1N9KE@1224|Proteobacteria,1SFHD@1236|Gammaproteobacteria,46C1C@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - HTH_17 k59_57350_22 1027273.GZ77_09015 1.09e-37 140.0 28HHC@1|root,2Z7T2@2|Bacteria,1PZ57@1224|Proteobacteria,1SRT1@1236|Gammaproteobacteria 1236|Gammaproteobacteria S AAA domain - - - - - - - - - - - - AAA_24 k59_156933_1 440250.A5HL28_9CAUD 2.11e-80 273.0 4QCM5@10239|Viruses,4QVZY@35237|dsDNA viruses no RNA stage,4QQFH@28883|Caudovirales,4QNDH@10744|Podoviridae 10744|Podoviridae S Bacteriophage head to tail connecting protein - GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019028,GO:0019058,GO:0019068,GO:0019072,GO:0019073,GO:0032991,GO:0044403,GO:0044419,GO:0044423,GO:0046798,GO:0051704 - - - - - - - - - - - k59_140623_2 492774.JQMB01000010_gene4567 1.26e-33 127.0 COG3179@1|root,COG3179@2|Bacteria,1RFSU@1224|Proteobacteria,2UDYJ@28211|Alphaproteobacteria,4BCH1@82115|Rhizobiaceae 28211|Alphaproteobacteria S chitinase - - - - - - - - - - - - Glyco_hydro_19 k59_246934_3 118161.KB235922_gene4822 2.22e-31 112.0 COG1351@1|root,COG1351@2|Bacteria,1G3FM@1117|Cyanobacteria,3VJQC@52604|Pleurocapsales 1117|Cyanobacteria F Thymidylate synthase complementing protein thyX - 2.1.1.148 ko:K03465 ko00240,ko00670,ko01100,map00240,map00670,map01100 - R06613 RC00022,RC00332 ko00000,ko00001,ko01000 - - - Thy1 k59_97686_1 44454.NF84_14495 7.71e-17 81.6 28PQS@1|root,2ZCCP@2|Bacteria,2IF0I@201174|Actinobacteria,236RC@1762|Mycobacteriaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_264748_2 1454202.PPBDW_90233___1 3.11e-12 67.0 COG4128@1|root,COG4128@2|Bacteria,1REHG@1224|Proteobacteria,1S491@1236|Gammaproteobacteria,1XW1I@135623|Vibrionales 135623|Vibrionales S Zonular occludens toxin (Zot) - - - - - - - - - - - - Zot k59_106610_2 489653.NLA_13540 4.64e-19 94.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,2VIKN@28216|Betaproteobacteria,2KPDW@206351|Neisseriales 206351|Neisseriales L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_206779_3 1385658.U5KNR1_9VIRU 2.83e-42 152.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_174078_3 948071.S4S2T1_9CAUD 1.02e-141 426.0 4QHPY@10239|Viruses,4QWIA@35237|dsDNA viruses no RNA stage,4QSXS@28883|Caudovirales,4QNJ2@10744|Podoviridae 10744|Podoviridae S host cell wall - - - - - - - - - - - - - k59_255431_1 1692249.A0A0K1RL40_9CIRC 2.63e-17 86.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_124346_2 1122201.AUAZ01000010_gene2520 1.17e-90 281.0 29UKS@1|root,30FY7@2|Bacteria,1RGKW@1224|Proteobacteria,1SKMS@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_197545_2 548479.HMPREF0573_11255 1.22e-08 55.5 2E38J@1|root,32Y88@2|Bacteria,2GX8Q@201174|Actinobacteria,4D7C7@85005|Actinomycetales 201174|Actinobacteria S VRR_NUC - - - - - - - - - - - - VRR_NUC k59_197545_4 1280671.AUJH01000012_gene3166 4.43e-25 110.0 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,2487V@186801|Clostridia,4BYZK@830|Butyrivibrio 186801|Clostridia L DNA polymerase family A - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_182527_2 1788447.A0A190WHJ9_9CIRC 1.15e-87 270.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_24993_1 439497.RR11_1905 1.99e-29 115.0 COG0582@1|root,COG0582@2|Bacteria,1R8G1@1224|Proteobacteria,2U3BN@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_integrase k59_165904_2 1788452.A0A190WHG0_9CIRC 1.41e-62 206.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_66422_2 929703.KE386491_gene3009 1.24e-05 48.5 COG1403@1|root,COG1403@2|Bacteria,4NJ0T@976|Bacteroidetes,47MEF@768503|Cytophagia 976|Bacteroidetes L HNH endonuclease - - - - - - - - - - - - HNH,HNH_5 k59_116222_1 675806.VII_003751 1.32e-13 76.6 COG0740@1|root,COG0740@2|Bacteria,1MUQ9@1224|Proteobacteria,1RRQA@1236|Gammaproteobacteria,1XWUR@135623|Vibrionales 135623|Vibrionales OU Clp protease - - - - - - - - - - - - CLP_protease k59_215709_7 411460.RUMTOR_01326 1.08e-33 119.0 2EN82@1|root,33FVV@2|Bacteria,1VKRH@1239|Firmicutes,24V2G@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_33272_3 655097.C8ZKH8_9CAUD 7.06e-156 451.0 4QGGR@10239|Viruses,4QZHR@35237|dsDNA viruses no RNA stage,4QUGZ@28883|Caudovirales,4QNY3@10744|Podoviridae 10744|Podoviridae S viral capsid - - - - - - - - - - - - - k59_33272_4 1173762.S4TT67_9CAUD 1.92e-57 199.0 4QCT5@10239|Viruses,4QYJH@35237|dsDNA viruses no RNA stage,4QTPG@28883|Caudovirales,4QNK2@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_58133_1 981335.G4W934_9CAUD 3.05e-57 187.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales 28883|Caudovirales S N-methyltransferase activity - - - - - - - - - - - - - k59_207420_1 272630.MexAM1_META1p3022 1.39e-18 89.7 COG1061@1|root,COG1061@2|Bacteria,1MV9F@1224|Proteobacteria,2TUXC@28211|Alphaproteobacteria,1JTIG@119045|Methylobacteriaceae 28211|Alphaproteobacteria L DEAD DEAH box helicase domain protein - - - ko:K19789 - - - - ko00000,ko03400 - - - DUF3427,HIT,Helicase_C,PLDc_2,ResIII,UPF0547 k59_240563_6 69279.BG36_03585 2.32e-93 299.0 COG1061@1|root,COG1061@2|Bacteria,1MV9F@1224|Proteobacteria,2V8QK@28211|Alphaproteobacteria,43QKU@69277|Phyllobacteriaceae 28211|Alphaproteobacteria L DEAD-like helicases superfamily - - - - - - - - - - - - Helicase_C,ResIII k59_240563_10 767434.Fraau_1474 1.17e-09 58.2 2DU37@1|root,33NS1@2|Bacteria,1N9FE@1224|Proteobacteria,1TM3Q@1236|Gammaproteobacteria,1X8XY@135614|Xanthomonadales 135614|Xanthomonadales S Protein of unknown function (DUF1364) - - - - - - - - - - - - DUF1364 k59_190_1 1215092.PA6_046_00270 7.45e-21 83.6 28QDM@1|root,2ZCVZ@2|Bacteria,1P5MR@1224|Proteobacteria,1SW6Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_199107_1 443152.MDG893_20679 6.33e-26 105.0 COG0237@1|root,COG0237@2|Bacteria,1NE9C@1224|Proteobacteria,1SCJ4@1236|Gammaproteobacteria 1236|Gammaproteobacteria H dephospho-CoA kinase activity - - - - - - - - - - - - - k59_124472_1 335543.Sfum_1893 1.1e-12 82.4 COG3210@1|root,COG4723@1|root,COG4733@1|root,COG3210@2|Bacteria,COG4723@2|Bacteria,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria,42QDD@68525|delta/epsilon subdivisions,2WIU9@28221|Deltaproteobacteria 28221|Deltaproteobacteria U Phage-related protein, tail - - - - - - - - - - - - Phage-tail_3 k59_116337_3 1449347.JQLN01000004_gene7029 1.45e-13 72.8 2C57A@1|root,33VMF@2|Bacteria,2ITD2@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - Peptidase_C1 k59_182606_1 1088721.NSU_0323 4.13e-78 247.0 COG5362@1|root,COG5362@2|Bacteria,1NKZK@1224|Proteobacteria,2U4BJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_83132_1 10717.Q9ZXE7_BPPH1 1.01e-13 75.5 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - GO:0008150,GO:0016032,GO:0019058,GO:0019068,GO:0044403,GO:0044419,GO:0051704,GO:0098003 - - - - - - - - - - - k59_158123_3 1229783.C273_01755 1.43e-13 68.6 COG1403@1|root,COG1403@2|Bacteria,1VH3I@1239|Firmicutes,4HPWS@91061|Bacilli,4GZVK@90964|Staphylococcaceae 91061|Bacilli L HNH nucleases - - - - - - - - - - - - HNH k59_133387_3 211165.AJLN01000015_gene2293 9.79e-19 104.0 COG0328@1|root,COG1539@1|root,COG0328@2|Bacteria,COG1539@2|Bacteria,1G326@1117|Cyanobacteria,1JGRS@1189|Stigonemataceae 1117|Cyanobacteria L RNA-DNA hybrid ribonuclease activity - - - - - - - - - - - - - k59_58647_1 343509.SG0856 2.75e-10 66.2 COG4385@1|root,COG4385@2|Bacteria,1N26V@1224|Proteobacteria,1S6M3@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Tail fiber protein - - - - - - - - - - - - Tail_P2_I k59_58647_2 598467.BrE312_3294 1.49e-13 75.1 COG3948@1|root,COG3948@2|Bacteria,1MUFF@1224|Proteobacteria,1RNBJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S baseplate assembly protein J - - - - - - - - - - - Baseplate_J k59_166517_4 438753.AZC_0840 3.35e-48 187.0 COG3170@1|root,COG3170@2|Bacteria,1R69E@1224|Proteobacteria,2U3B9@28211|Alphaproteobacteria 28211|Alphaproteobacteria NU Phage P22-like portal protein - - - - - - - - - - - - - k59_241101_1 948071.S4S2D9_9CAUD 7.85e-184 535.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QNQ6@10744|Podoviridae 10744|Podoviridae S ribonucleoside-triphosphate reductase activity - - - - - - - - - - - - - k59_141831_13 688245.CtCNB1_1438 1.8e-63 205.0 28J67@1|root,2Z91Y@2|Bacteria,1R7RG@1224|Proteobacteria,2VRTM@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_34038_1 1123279.ATUS01000005_gene3110 4.53e-53 190.0 COG1196@1|root,COG2911@1|root,COG1196@2|Bacteria,COG2911@2|Bacteria 2|Bacteria S protein secretion sca1 - - - - - - - - - - - Autotransporter,DUF4114,SLT,Tape_meas_lam_C,VPEP k59_841_1 1123371.ATXH01000008_gene281 5.26e-16 87.4 COG0587@1|root,COG0587@2|Bacteria,2GGUN@200940|Thermodesulfobacteria 2|Bacteria L Bacterial DNA polymerase III alpha subunit dnaE2 - 2.7.7.7 ko:K02337,ko:K14162 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP k59_257914_2 655097.C8ZKE0_9CAUD 2.26e-10 63.9 4QBG4@10239|Viruses,4QUZA@35237|dsDNA viruses no RNA stage,4QRSK@28883|Caudovirales,4QP0Z@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_42238_1 1618248.A0A0C5IB82_9CIRC 6.07e-79 249.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_249524_1 1192868.CAIU01000008_gene927 3.13e-124 373.0 COG1783@1|root,COG1783@2|Bacteria,1PE12@1224|Proteobacteria,2V9EC@28211|Alphaproteobacteria,43QJZ@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Mu-like prophage FluMu protein gp28 - - - - - - - - - - - - - k59_158219_2 570952.ATVH01000011_gene353 6.13e-51 189.0 2EXSU@1|root,33R23@2|Bacteria,1NS77@1224|Proteobacteria,2UR4M@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_183219_2 1120942.AUBM01000008_gene129 1.4e-19 92.0 COG0553@1|root,COG0553@2|Bacteria,2GISC@201174|Actinobacteria,4D3XH@85005|Actinomycetales 201174|Actinobacteria KL SNF2 family N-terminal domain protein helZ - - - - - - - - - - - Helicase_C,SNF2_N,SNF2_assoc,SWIM k59_191350_1 691965.D4P7L7_9CAUD 1.2e-70 243.0 4QB9J@10239|Viruses,4QXFE@35237|dsDNA viruses no RNA stage,4QS1Z@28883|Caudovirales,4QN8F@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_25768_2 1385658.U5KPZ6_9VIRU 3.86e-203 583.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_26594_4 1498011.A0A096XUV7_9CAUD 1.37e-65 215.0 4QB5I@10239|Viruses,4QPQ9@28883|Caudovirales,4QNX6@10744|Podoviridae 10744|Podoviridae S Helicase conserved C-terminal domain - - - - - - - - - - - - - k59_167472_4 953739.SVEN_2129 8.56e-30 112.0 2BM0Q@1|root,32FHM@2|Bacteria,2IK53@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_217421_1 1192868.CAIU01000008_gene938 3.39e-16 85.1 COG0553@1|root,COG0553@2|Bacteria,1R7CK@1224|Proteobacteria,2U228@28211|Alphaproteobacteria,43I7K@69277|Phyllobacteriaceae 28211|Alphaproteobacteria KL DEAD-like helicases superfamily - - - - - - - - - - - - Helicase_C,N6_N4_Mtase k59_142644_1 935565.JAEM01000006_gene3909 2.43e-40 140.0 COG5323@1|root,COG5323@2|Bacteria 2|Bacteria M Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6 k59_1730_1 1618248.A0A0C5IB82_9CIRC 8.16e-09 60.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_200379_2 1089439.KB902270_gene2571 5.69e-35 137.0 COG3299@1|root,COG3299@2|Bacteria,1PYEJ@1224|Proteobacteria 1224|Proteobacteria S Baseplate J family protein - - - - - - - - - - - - Baseplate_J k59_109242_3 1121887.AUDK01000007_gene1777 2.05e-24 101.0 2BNNK@1|root,32HBI@2|Bacteria,4PDBS@976|Bacteroidetes,1IDUK@117743|Flavobacteriia,2NZ8T@237|Flavobacterium 976|Bacteroidetes - - - - - - - - - - - - - - - k59_26604_2 1392486.JIAF01000004_gene2646 5.78e-10 58.5 COG0847@1|root,COG0847@2|Bacteria,4NPNG@976|Bacteroidetes,2FS7S@200643|Bacteroidia 976|Bacteroidetes L Exonuclease - - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T k59_84243_2 105154.Q9MBU6_9VIRU 1.4e-26 108.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_43043_1 1379713.S5SYD9_9CIRC 1.3e-27 114.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_1731_1 1609634.A0A0C5AFT2_9VIRU 3.06e-68 223.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_1731_3 1385658.U5KPZ6_9VIRU 6.6e-68 223.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_175327_2 1609634.A0A0C5AFV4_9VIRU 3.75e-80 262.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_134330_4 1234888.K0A2J2_9VIRU 3.29e-116 357.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_43047_1 1986029.Q9MBM6_9VIRU 2.53e-13 70.5 4QDBB@10239|Viruses,4QUM0@29258|ssDNA viruses,4QP4D@10841|Microviridae 10841|Microviridae S Chlamydia-phage Chp2 scaffold (Chlamy_scaf) - - - - - - - - - - - - - k59_68581_3 1609634.A0A0C5AFV4_9VIRU 1.59e-59 201.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_27515_1 536019.Mesop_3763 8.73e-72 236.0 2EAGC@1|root,334JN@2|Bacteria,1N1US@1224|Proteobacteria,2UEQF@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_135265_2 1234888.K0A2J2_9VIRU 3.62e-133 401.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_135265_4 1234888.K0A2R8_9VIRU 9.29e-31 122.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_10323_1 1144313.PMI10_02192 4.61e-05 56.2 COG1345@1|root,COG3386@1|root,COG1345@2|Bacteria,COG3386@2|Bacteria,4NM9F@976|Bacteroidetes,1I33Y@117743|Flavobacteriia,2P0DI@237|Flavobacterium 976|Bacteroidetes GN Domain of unknown function (DUF5122) beta-propeller - - - - - - - - - - - - DUF5008,DUF5122,DUF5124 k59_10323_2 211114.JOEF01000022_gene5584 3.28e-13 78.6 2E9RT@1|root,333Y0@2|Bacteria,2IESW@201174|Actinobacteria,4E4UX@85010|Pseudonocardiales 201174|Actinobacteria S Siphovirus ReqiPepy6 Gp37-like protein - - - - - - - - - - - - Sipho_Gp37 k59_127088_1 223283.PSPTO_0344 5.03e-22 103.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1Z75P@136849|Pseudomonas syringae group 1236|Gammaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_151899_1 1150599.MPHLEI_07809 3.13e-17 78.6 arCOG05626@1|root,32V4D@2|Bacteria,2I38M@201174|Actinobacteria,23FBM@1762|Mycobacteriaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_151899_4 691965.D4P7L3_9CAUD 1.32e-144 429.0 4QBH7@10239|Viruses,4QWWF@35237|dsDNA viruses no RNA stage,4QQ8R@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_68743_2 69014.TK2143 8.21e-39 138.0 COG1573@1|root,arCOG00905@2157|Archaea,2XUVI@28890|Euryarchaeota,243FM@183968|Thermococci 183968|Thermococci L Uracil DNA glycosylase superfamily - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k59_259822_1 1618247.A0A0C5I2K0_9CIRC 6.48e-23 103.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_2847_1 105154.Q9MBU6_9VIRU 1.19e-96 305.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_143855_1 1609634.A0A0C5ANA6_9VIRU 1.09e-08 59.3 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_218703_1 1692252.A0A0K1RL35_9CIRC 1.78e-36 134.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_218703_2 650150.ERH_1292 4.27e-10 64.3 28MKK@1|root,2ZAWR@2|Bacteria,1UYAT@1239|Firmicutes,3VSD5@526524|Erysipelotrichia 526524|Erysipelotrichia S Putative viral replication protein - - - - - - - - - - - - RNA_helicase,Viral_Rep k59_27652_1 987059.RBXJA2T_03793 5.61e-10 65.9 COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,2VHH0@28216|Betaproteobacteria,1KIWU@119065|unclassified Burkholderiales 28216|Betaproteobacteria L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA - - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N k59_201454_1 490913.C4NTD5_9CAUD 9.38e-22 94.0 4QGA5@10239|Viruses,4QURD@35237|dsDNA viruses no RNA stage,4QT9N@28883|Caudovirales,4QP47@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_201454_2 1477404.A0A023NHR5_9CAUD 8.95e-196 548.0 4QEG2@10239|Viruses,4QVSD@35237|dsDNA viruses no RNA stage,4QRJ9@28883|Caudovirales,4QP0R@10744|Podoviridae 10744|Podoviridae S exonuclease activity - - - - - - - - - - - - - k59_201454_3 490913.C4NTD1_9CAUD 3.62e-119 366.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_44005_1 1500301.JQMF01000006_gene1773 8.52e-11 67.4 COG5108@1|root,COG5108@2|Bacteria,1PIWB@1224|Proteobacteria,2U1JR@28211|Alphaproteobacteria,4BC0X@82115|Rhizobiaceae 28211|Alphaproteobacteria K DNA-directed RNA polymerase N-terminal - - - - - - - - - - - - RNA_pol,RPOL_N k59_234187_2 1370120.AUWR01000008_gene337 4.43e-08 58.5 COG0791@1|root,COG0791@2|Bacteria,2GIWB@201174|Actinobacteria,233BD@1762|Mycobacteriaceae 201174|Actinobacteria M NlpC/P60 family - GO:0005575,GO:0005576 - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - NLPC_P60 k59_193741_3 329381.D9ICX0_9CAUD 7.26e-14 82.8 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QI82@10662|Myoviridae 10662|Myoviridae S virus tail, fiber - - - - - - - - - - - - - k59_36398_1 118161.KB235922_gene5776 4.36e-15 77.0 COG1672@1|root,COG1672@2|Bacteria,1G5IV@1117|Cyanobacteria 1117|Cyanobacteria O Tetratricopeptide repeat - - - - - - - - - - - - AAA_22,CHAT,TIR_2,Trypsin_2 k59_243662_1 1618259.A0A0C5I2B5_9CIRC 6.06e-38 135.0 4QE84@10239|Viruses,4QUKR@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_85791_2 742740.HMPREF9474_02267 6.45e-48 162.0 28NM4@1|root,2ZBMQ@2|Bacteria,1V1QD@1239|Firmicutes,24G1B@186801|Clostridia,221N8@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_70026_1 1504822.CCNO01000015_gene594 5.03e-80 264.0 COG0553@1|root,COG0863@1|root,COG0553@2|Bacteria,COG0863@2|Bacteria 2|Bacteria L N-4 methylation of cytosine - - - - - - - - - - - - Helicase_C,N6_N4_Mtase,SNF2_N k59_210433_2 49964.Q94MS1_9CAUD 6.89e-69 220.0 4QB4H@10239|Viruses,4QYQI@35237|dsDNA viruses no RNA stage,4QUAR@28883|Caudovirales,4QNUV@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_136556_2 428125.CLOLEP_01398 3.17e-34 120.0 2CGGB@1|root,32UNH@2|Bacteria,1VD9W@1239|Firmicutes,24MWC@186801|Clostridia,3WPKG@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_136556_3 742740.HMPREF9474_02279 8.92e-49 161.0 29YRZ@1|root,30KMY@2|Bacteria,1V4Y4@1239|Firmicutes,24HPY@186801|Clostridia,221XY@1506553|Lachnoclostridium 186801|Clostridia S Protein of unknown function (DUF2800) - - - - - - - - - - - - DUF2800 k59_78387_1 743719.PaelaDRAFT_2395 0.000324 50.8 COG1783@1|root,COG1783@2|Bacteria,1TRQP@1239|Firmicutes,4HCUQ@91061|Bacilli,275JZ@186822|Paenibacillaceae 91061|Bacilli S Phage terminase large subunit - - - - - - - - - - - - Terminase_3,Terminase_3C k59_169932_4 1089548.KI783301_gene2632 9.93e-35 146.0 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,4H9Z7@91061|Bacilli 91061|Bacilli L DNA polymerase - - - - - - - - - - - - DNA_pol_A k59_220341_1 56110.Oscil6304_6015 1.85e-67 213.0 COG1961@1|root,COG1961@2|Bacteria,1G6E1@1117|Cyanobacteria,1HDPW@1150|Oscillatoriales 1117|Cyanobacteria L Resolvase, N terminal domain xisF - - - - - - - - - - - Recombinase,Resolvase,Zn_ribbon_recom k59_251915_1 1458858.A0A088C3U3_9CAUD 7.83e-38 135.0 4QAMW@10239|Viruses,4QV5I@35237|dsDNA viruses no RNA stage,4QRGE@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_70031_2 1165094.RINTHH_3920 8.69e-25 101.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_19670_4 1220601.L7TQW5_9CAUD 2.72e-45 169.0 4QBMV@10239|Viruses,4QUU6@35237|dsDNA viruses no RNA stage,4QQ7Y@28883|Caudovirales 28883|Caudovirales S DNA-dependent RNA polymerase - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_253045_1 1340493.JNIF01000003_gene2799 1.7e-10 68.2 COG0457@1|root,COG0457@2|Bacteria,3Y7H0@57723|Acidobacteria 57723|Acidobacteria S Tetratricopeptide repeat - - - - - - - - - - - - Glyco_transf_9,TPR_16 k59_187438_1 1147139.A0A0A6Z582_9CAUD 7.66e-10 62.0 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales,4QNBQ@10744|Podoviridae 10744|Podoviridae S HNH endonuclease - - - - - - - - - - - - - k59_129973_1 42099.EPrPV00000018749 4.2e-06 53.5 COG1404@1|root,KOG4266@2759|Eukaryota,1MFB0@121069|Pythiales 121069|Pythiales O serine protease. Source PGD - - - - - - - - - - - - Peptidase_S8 k59_236238_1 402881.Plav_1283 1.25e-15 78.2 COG0438@1|root,COG0438@2|Bacteria,1QY7T@1224|Proteobacteria,2TXJ6@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Sulfotransferase domain - - 2.8.2.1 ko:K01014 ko05204,map05204 - R01242 RC00007,RC00128 ko00000,ko00001,ko01000 - - - Sulfotransfer_1 k59_228998_2 105154.Q9MBU6_9VIRU 7.73e-65 216.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_262142_1 484022.Fphi_1687 1.61e-32 128.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,45ZTN@72273|Thiotrichales 72273|Thiotrichales L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_104222_2 1266909.AUAG01000012_gene979 8.39e-08 58.5 COG0210@1|root,COG0210@2|Bacteria,1R4PV@1224|Proteobacteria,1RZXT@1236|Gammaproteobacteria 1236|Gammaproteobacteria L DNA helicase - - - - - - - - - - - - AAA_19,UvrD-helicase,UvrD_C,UvrD_C_2 k59_30261_1 1121422.AUMW01000016_gene2063 0.000288 48.9 COG5434@1|root,COG5434@2|Bacteria,1UJS5@1239|Firmicutes,24VP2@186801|Clostridia,266SC@186807|Peptococcaceae 186801|Clostridia M Right handed beta helix region - - - - - - - - - - - - Beta_helix k59_12814_1 194867.ALBQ01000016_gene3018 5.46e-38 142.0 COG4653@1|root,COG4653@2|Bacteria,1Q3BS@1224|Proteobacteria,2TW86@28211|Alphaproteobacteria,2K50B@204457|Sphingomonadales 204457|Sphingomonadales S Phage capsid family - - - - - - - - - - - - Phage_capsid k59_12814_3 1231190.NA8A_23384 6.79e-133 395.0 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,2V9W4@28211|Alphaproteobacteria,43NEB@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Phage portal protein - - - - - - - - - - - - Phage_portal k59_187625_5 1121127.JAFA01000012_gene7335 1.69e-24 94.0 COG2378@1|root,COG2378@2|Bacteria 2|Bacteria K regulation of single-species biofilm formation - - - - - - - - - - - - HTH_11 k59_204314_1 380358.XALC_1544 2.94e-49 169.0 COG2946@1|root,COG2946@2|Bacteria,1RDKM@1224|Proteobacteria,1S46D@1236|Gammaproteobacteria,1X9BS@135614|Xanthomonadales 135614|Xanthomonadales L Replication initiation factor - - - ko:K07467 - - - - ko00000 - - - Rep_trans k59_179181_1 1234888.K0A2J2_9VIRU 4.71e-47 169.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_138054_1 1788455.A0A190WHF5_9CIRC 2.56e-08 55.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_113523_1 926550.CLDAP_02830 5.2e-24 94.7 COG2131@1|root,COG2131@2|Bacteria,2G7AC@200795|Chloroflexi 200795|Chloroflexi F MafB19-like deaminase - - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 k59_237338_1 649747.HMPREF0083_01029 4.03e-43 152.0 COG4422@1|root,COG4422@2|Bacteria,1TPP1@1239|Firmicutes,4HAU8@91061|Bacilli,26V16@186822|Paenibacillaceae 91061|Bacilli S Protein of unknown function (DUF5131) - - - - - - - - - - - - DUF5131 k59_7285_4 744980.TRICHSKD4_6171 7.9e-87 263.0 COG1961@1|root,COG1961@2|Bacteria,1MXXT@1224|Proteobacteria,2U9WZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Site-specific recombinases, DNA invertase Pin homologs - - - ko:K14060 - - - - ko00000 - - - Resolvase k59_223417_1 1123508.JH636439_gene1604 1.33e-12 71.2 29XN2@1|root,30JDF@2|Bacteria,2J498@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - k59_237487_3 1423321.AS29_12475 5.25e-13 77.8 COG1404@1|root,COG1404@2|Bacteria,1TPZ5@1239|Firmicutes,4HA5F@91061|Bacilli,1ZPUP@1386|Bacillus 91061|Bacilli O Belongs to the peptidase S8 family isp - - ko:K13275 - - - - ko00000,ko01000,ko01002,ko03110 - - - Peptidase_S8 k59_123140_1 1517681.HW45_02700 1.27e-20 100.0 COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,1QZAD@1224|Proteobacteria,1RYP3@1236|Gammaproteobacteria 1236|Gammaproteobacteria D nuclear chromosome segregation - - - - - - - - - - - - - k59_114982_2 1692259.A0A0K1RL59_9CIRC 1.04e-29 122.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_180489_1 937777.Deipe_1458 2.11e-21 102.0 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria 2|Bacteria K chromosome segregation - - - - - - - - - - - - Terminase_6,Terminase_6C k59_189387_1 440250.A5HL24_9CAUD 2.3e-27 116.0 4QGKB@10239|Viruses,4QZ0P@35237|dsDNA viruses no RNA stage,4QSXQ@28883|Caudovirales,4QNSQ@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_131392_1 105154.Q9MBU6_9VIRU 1.47e-53 183.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_163538_1 1197906.CAJQ02000023_gene2189 7.68e-22 95.5 COG0451@1|root,COG0451@2|Bacteria,1RKFJ@1224|Proteobacteria,2UAT9@28211|Alphaproteobacteria 28211|Alphaproteobacteria GM 3-beta hydroxysteroid dehydrogenase/isomerase family - - - - - - - - - - - - Epimerase k59_31892_1 642492.Clole_1479 4.04e-16 77.8 COG3935@1|root,COG3935@2|Bacteria,1W6YJ@1239|Firmicutes,24P7D@186801|Clostridia 186801|Clostridia L DnaD domain protein - - - - - - - - - - - - - k59_72897_2 61647.LG71_19615 6.22e-22 90.9 COG4570@1|root,COG4570@2|Bacteria,1N92D@1224|Proteobacteria,1S5SJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC rusA - 3.1.22.4 ko:K01160 - - - - ko00000,ko01000,ko03400 - - - RusA k59_231255_1 1262513.K7YB38_9CAUD 4.86e-70 234.0 4QBG0@10239|Viruses,4QWYZ@35237|dsDNA viruses no RNA stage,4QSGM@28883|Caudovirales,4QK1H@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_255241_3 871968.DESME_08930 7.39e-69 242.0 2E2CM@1|root,32XHK@2|Bacteria,1VCFP@1239|Firmicutes,24Q3M@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_206669_2 1088868.CIN_02710 8.45e-06 55.1 COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,2UIYJ@28211|Alphaproteobacteria,2JZ97@204441|Rhodospirillales 204441|Rhodospirillales M Glycosyltransferase family 9 (heptosyltransferase) - - - - - - - - - - - - Glyco_transf_9 k59_73881_1 1379715.S5TMW6_9CIRC 1.84e-27 113.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_73881_3 1379715.S5TMW6_9CIRC 2.38e-10 61.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_33084_1 866889.E1XUA1_9CAUD 3.13e-06 52.0 4QG66@10239|Viruses,4QUJP@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_173941_2 857087.Metme_1986 2.72e-14 67.4 2ER1H@1|root,33IM1@2|Bacteria,1NKBQ@1224|Proteobacteria,1SH23@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_173941_3 305700.B447_02451 3.54e-16 79.0 COG1192@1|root,COG1192@2|Bacteria,1Q9XV@1224|Proteobacteria,2VR8E@28216|Betaproteobacteria,2KUYF@206389|Rhodocyclales 206389|Rhodocyclales D Cobyrinic acid ac-diamide synthase - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 k59_64240_1 105154.Q9MBU6_9VIRU 2.38e-33 128.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_64240_2 105154.Q9MBU3_9VIRU 2.22e-17 84.3 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_124213_1 313596.RB2501_14029 2.24e-30 113.0 COG0860@1|root,COG0860@2|Bacteria,4NR00@976|Bacteroidetes,1I4WN@117743|Flavobacteriia 976|Bacteroidetes M N-acetylmuramoyl-L-alanine amidase - - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3 k59_190529_2 439235.Dalk_3976 3.99e-28 113.0 COG4675@1|root,COG4675@2|Bacteria,1PFYN@1224|Proteobacteria,436DC@68525|delta/epsilon subdivisions,2X0YN@28221|Deltaproteobacteria,2MP2M@213118|Desulfobacterales 28221|Deltaproteobacteria S Phage Tail Collar Domain - - - - - - - - - - - - Collar k59_14875_1 478749.BRYFOR_08560 1.92e-48 176.0 COG3378@1|root,COG3378@2|Bacteria 2|Bacteria KL Phage plasmid primase P4 family - - - ko:K06919 - - - - ko00000 - - - D5_N,DUF3854,P22_AR_N,Pox_D5 k59_255484_1 311424.DhcVS_1286 5.1e-16 82.4 2DBHG@1|root,2Z99H@2|Bacteria 2|Bacteria - - mom - - ko:K21527 - - - - ko00000,ko01000 - - - - k59_81815_1 1692256.A0A0K1RL85_9CIRC 8.74e-11 62.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_82571_4 1540097.A0A0A0YPX0_9CAUD 2.32e-127 374.0 4QEG2@10239|Viruses,4QRJ9@28883|Caudovirales,4QP0R@10744|Podoviridae 10744|Podoviridae S exonuclease activity - - - - - - - - - - - - - k59_65193_1 186617.M9M8L2_9VIRU 1.55e-55 190.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_264966_3 10228.TriadP52877 7.53e-29 115.0 2D04N@1|root,2SCSW@2759|Eukaryota,3AE35@33154|Opisthokonta 33154|Opisthokonta - - - - - - - - - - - - - - - k59_65194_1 4572.TRIUR3_27906-P1 1.98e-11 68.6 COG0484@1|root,KOG0713@2759|Eukaryota,37IWE@33090|Viridiplantae,3G8YA@35493|Streptophyta,3M45X@4447|Liliopsida,3ICNJ@38820|Poales 35493|Streptophyta O DnaJ molecular chaperone homology domain - GO:0001101,GO:0008150,GO:0009719,GO:0009725,GO:0009737,GO:0010033,GO:0033993,GO:0042221,GO:0050896,GO:0097305,GO:1901700 - - - - - - - - - - DnaJ k59_198411_1 1166018.FAES_4024 2.82e-06 55.5 29YBT@1|root,30K65@2|Bacteria,4NY8W@976|Bacteroidetes,47SZM@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_165685_2 1461580.CCAS010000060_gene3848 1.27e-11 67.4 COG3409@1|root,COG3409@2|Bacteria,1TPV1@1239|Firmicutes,4HI6Q@91061|Bacilli 91061|Bacilli M Domain of unknown function (DUF1906) - - - - - - - - - - - - DUF1906,PG_binding_1 k59_214846_1 105154.Q9MBU6_9VIRU 1.06e-106 325.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_24580_1 795797.C497_05662 6.4e-11 70.1 COG5283@1|root,arCOG11109@2157|Archaea,2Y67M@28890|Euryarchaeota,23YYB@183963|Halobacteria 183963|Halobacteria S Phage tail tape measure protein, TP901 family - - - - - - - - - - - - PhageMin_Tail k59_214854_2 670307.HYPDE_23298 6.69e-05 48.5 2C4D9@1|root,337PW@2|Bacteria,1NE4W@1224|Proteobacteria,2VGN3@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF1353) - - - - - - - - - - - - DUF1353 k59_82766_2 391595.RLO149_c014800 3.01e-17 81.6 2EJIR@1|root,33D9N@2|Bacteria,1NHKK@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - DUF4376,Phage_tail_APC k59_82766_6 910314.HMPREF9220_1083 2.66e-07 62.8 COG1511@1|root,COG4733@1|root,COG1511@2|Bacteria,COG4733@2|Bacteria,1TSG2@1239|Firmicutes,4H6TK@909932|Negativicutes 909932|Negativicutes S gp58-like protein - - - - - - - - - - - - Phage-tail_3 k59_247854_2 1526550.A0A088F868_9VIRU 2.96e-16 75.1 4QD1J@10239|Viruses 10239|Viruses S Protein of unknown function (DUF1364) - - - - - - - - - - - - - k59_75307_2 13690.CP98_05000 2.68e-84 266.0 COG4653@1|root,COG4653@2|Bacteria,1Q3BS@1224|Proteobacteria,2TW86@28211|Alphaproteobacteria,2K50B@204457|Sphingomonadales 204457|Sphingomonadales S Phage capsid family - - - - - - - - - - - - Phage_capsid k59_75308_1 1385658.U5KPZ6_9VIRU 5.33e-81 259.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_183098_1 1391038.T1YSF1_9VIRU 2.75e-68 215.0 4QB6C@10239|Viruses 10239|Viruses L Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_183098_2 1391034.T1YRW5_9VIRU 6.94e-48 167.0 4QAZA@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_183098_4 1391038.T1YSF1_9VIRU 6.8e-95 286.0 4QB6C@10239|Viruses 10239|Viruses L Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_17097_1 1692249.A0A0K1RLN8_9CIRC 6.06e-27 110.0 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_167544_2 1526550.A0A088F868_9VIRU 1.29e-20 86.3 4QD1J@10239|Viruses 10239|Viruses S Protein of unknown function (DUF1364) - - - - - - - - - - - - - k59_51411_1 644076.SCH4B_4375 1.19e-40 140.0 2AJ1X@1|root,319K5@2|Bacteria,1RK0X@1224|Proteobacteria,2UKUD@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF2829) - - - - - - - - - - - - DUF2829 k59_51411_3 1123269.NX02_04065 3.14e-28 110.0 28HXV@1|root,2Z83C@2|Bacteria,1PJBP@1224|Proteobacteria,2U8DN@28211|Alphaproteobacteria,2K5CZ@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - k59_76314_1 1415754.JQMK01000012_gene921 4.57e-13 73.9 COG1061@1|root,COG1061@2|Bacteria,1MV9F@1224|Proteobacteria,1RNAN@1236|Gammaproteobacteria,4659W@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG1061 DNA or RNA helicases of superfamily II yejH GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042221,GO:0042493,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051301,GO:0051716,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - ko:K19789 - - - - ko00000,ko03400 - - - Helicase_C,ResIII k59_17737_1 1692242.A0A0K1RKZ2_9CIRC 1.32e-25 108.0 4QFEW@10239|Viruses,4QUKZ@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_1826_2 1116369.KB890024_gene2562 1.26e-09 59.3 2E6IZ@1|root,33162@2|Bacteria,1N85B@1224|Proteobacteria,2UH5M@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Domain of unknown function (DUF4326) - - - - - - - - - - - - DUF4326 k59_134426_1 742740.HMPREF9474_02271 6.18e-83 263.0 28J3N@1|root,2Z8ZU@2|Bacteria,1V15Z@1239|Firmicutes,249Z0@186801|Clostridia,221RR@1506553|Lachnoclostridium 186801|Clostridia S Phage portal protein - - - - - - - - - - - - Phage_portal k59_117914_2 1385658.U5KPZ6_9VIRU 5.06e-202 580.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_51517_1 888060.HMPREF9081_0862 1.12e-11 68.6 COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,4H2HH@909932|Negativicutes 909932|Negativicutes E Belongs to the DegT DnrJ EryC1 family - - - - - - - - - - - - DegT_DnrJ_EryC1 k59_34906_6 268748.Q58N42_BPPRP 5.94e-15 79.0 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales,4QNBW@10744|Podoviridae 10744|Podoviridae S DNA helicase activity - - - - - - - - - - - - - k59_158942_1 1477404.A0A023NGA9_9CAUD 1.38e-61 209.0 4QCA4@10239|Viruses,4QZXY@35237|dsDNA viruses no RNA stage,4QRMB@28883|Caudovirales,4QNJI@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_1988_1 1385658.U5KPZ6_9VIRU 3.76e-129 387.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_225768_1 1609634.A0A0C5AFT2_9VIRU 4.6e-13 70.1 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_17829_1 1385658.U5KPZ6_9VIRU 9.92e-112 342.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_17829_3 10855.REP_SPV4 7.46e-21 95.5 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_43320_1 1548905.A0A0A1IVS4_9CAUD 7.05e-92 277.0 4QH9I@10239|Viruses,4QTW6@28883|Caudovirales,4QMZW@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_43320_2 1548905.A0A0A1IV69_9CAUD 1.67e-34 124.0 4QF2R@10239|Viruses,4QPI5@28883|Caudovirales,4QMKW@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_259043_3 319795.Dgeo_0872 8.07e-45 157.0 COG0714@1|root,COG0714@2|Bacteria,1WKMC@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S AAA domain (dynein-related subfamily) - - - - - - - - - - - - AAA_5 k59_167684_1 366394.Smed_1911 4.64e-53 175.0 COG2813@1|root,COG2813@2|Bacteria,1QYWA@1224|Proteobacteria,2TY0H@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Specifically methylates the guanine in position - - - - - - - - - - - - - k59_126308_1 365659.smi_0426 2.2e-11 63.2 2DJ23@1|root,32UC6@2|Bacteria,1VA3C@1239|Firmicutes,4HM73@91061|Bacilli 91061|Bacilli S VRR-NUC domain - - - - - - - - - - - - VRR_NUC k59_126308_2 1392487.JIAD01000001_gene369 8.34e-08 61.6 COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,2480W@186801|Clostridia,25V6T@186806|Eubacteriaceae 186801|Clostridia L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 k59_126308_8 795666.MW7_1076 5.39e-32 131.0 COG3378@1|root,COG3378@2|Bacteria,1MV7I@1224|Proteobacteria,2VM9Y@28216|Betaproteobacteria,1K6UZ@119060|Burkholderiaceae 28216|Betaproteobacteria S D5 N terminal like - - - ko:K06919 - - - - ko00000 - - - D5_N,PriCT_2 k59_9779_1 1079460.ATTQ01000011_gene2946 8.62e-25 107.0 COG1573@1|root,COG1573@2|Bacteria,1MW8T@1224|Proteobacteria,2TSAR@28211|Alphaproteobacteria,4BD94@82115|Rhizobiaceae 28211|Alphaproteobacteria L uracil-DNA glycosylase - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - DUF4130,UDG k59_18793_5 1234888.K0A2J2_9VIRU 2.9e-161 473.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_119279_15 1121441.AUCX01000014_gene507 2.52e-14 86.3 COG5563@1|root,COG5563@2|Bacteria,1Q0JE@1224|Proteobacteria,430IH@68525|delta/epsilon subdivisions,2X0GF@28221|Deltaproteobacteria,2MD65@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_119279_16 938709.AUSH02000051_gene289 0.00033 53.9 COG4675@1|root,COG4675@2|Bacteria 2|Bacteria M tail collar domain protein - - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - Collar,Phage_fiber_2 k59_176852_3 1196083.SALWKB12_0209 0.000775 49.3 COG2946@1|root,COG2946@2|Bacteria,1RDKM@1224|Proteobacteria,2VNHY@28216|Betaproteobacteria,2KQIU@206351|Neisseriales 206351|Neisseriales L Replication initiation factor - - - - - - - - - - - - Rep_trans k59_102330_3 105154.Q9MBU6_9VIRU 5.51e-110 337.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_168984_1 1197951.I6S2A9_9CAUD 9.25e-70 231.0 4QCM5@10239|Viruses,4QVZY@35237|dsDNA viruses no RNA stage,4QQFH@28883|Caudovirales 28883|Caudovirales S Bacteriophage head to tail connecting protein - GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019028,GO:0019058,GO:0019068,GO:0019072,GO:0019073,GO:0032991,GO:0044403,GO:0044419,GO:0044423,GO:0046798,GO:0051704 - - - - - - - - - - - k59_36747_2 1609634.A0A0C5AFV4_9VIRU 8.73e-118 357.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_70234_1 1035191.HMPREF0185_03271 6.01e-35 131.0 COG4227@1|root,COG4227@2|Bacteria,1MU8I@1224|Proteobacteria,2TRIT@28211|Alphaproteobacteria,2KI4E@204458|Caulobacterales 204458|Caulobacterales L Domain of unknown function (DUF1738) - - - - - - - - - - - - DUF1738 k59_227974_1 439375.Oant_1512 5.13e-10 56.2 2BZTS@1|root,33131@2|Bacteria,1NBBP@1224|Proteobacteria,2UIZA@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_19863_1 1166948.JPZL01000002_gene1842 1.77e-51 191.0 28P6A@1|root,2ZC10@2|Bacteria,1RBZE@1224|Proteobacteria,1RRNS@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_145614_1 937777.Deipe_0444 1.84e-07 51.6 COG0270@1|root,COG0270@2|Bacteria 2|Bacteria L DNA (cytosine-5-)-methyltransferase activity - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_4691_3 497965.Cyan7822_4104 2.39e-05 45.4 28S6Y@1|root,2ZEIG@2|Bacteria,1GH0B@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - k59_36756_1 1609634.A0A0C5ANA6_9VIRU 5e-17 79.3 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_244001_1 691965.D4P7E6_9CAUD 2.74e-17 95.5 4QAK6@10239|Viruses,4R01K@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_103251_1 145579.H_BPPHM 5.89e-10 60.5 4QCA6@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_103251_2 1385658.U5KPZ6_9VIRU 4.34e-96 298.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_86010_1 1385658.U5KPZ6_9VIRU 3.9e-56 194.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_112102_3 371731.Rsw2DRAFT_1087 1.13e-68 211.0 COG3023@1|root,COG3023@2|Bacteria,1N032@1224|Proteobacteria,2U2D2@28211|Alphaproteobacteria,1FCZU@1060|Rhodobacter 28211|Alphaproteobacteria V N-acetylmuramoyl-L-alanine amidase - - 3.5.1.28 ko:K01447 - - R04112 RC00064,RC00141 ko00000,ko01000 - - - Amidase_2,PG_binding_1 k59_70359_1 1234888.K0A2J2_9VIRU 3.28e-44 160.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_228108_1 151528.Q8W707_9CAUD 4.22e-23 98.2 4QAM2@10239|Viruses,4QV3W@35237|dsDNA viruses no RNA stage,4QPGK@28883|Caudovirales,4QNW0@10744|Podoviridae 10744|Podoviridae S exonuclease activity - GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 - - - - - - - - - - - k59_137017_3 1123508.JH636464_gene272 1.43e-42 154.0 28HHC@1|root,2Z7T2@2|Bacteria,2J15Z@203682|Planctomycetes 203682|Planctomycetes S AAA domain - - - - - - - - - - - - AAA_24 k59_4832_2 663278.Ethha_0496 5.08e-19 86.7 COG4653@1|root,COG4653@2|Bacteria,1UZMZ@1239|Firmicutes,24BQJ@186801|Clostridia,3WR58@541000|Ruminococcaceae 186801|Clostridia S Phage capsid family - - - - - - - - - - - - CarboxypepD_reg,Phage_capsid k59_261391_1 105154.Q9MBU3_9VIRU 1.66e-11 68.9 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_261391_2 1609634.A0A0C5AFV4_9VIRU 2.99e-10 60.5 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_203253_1 1449068.JMLQ01000004_gene1111 2.9e-12 66.6 arCOG05626@1|root,2Z9D9@2|Bacteria,2IIAB@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_78742_1 352165.HMPREF7215_2595 2.99e-05 53.5 COG3170@1|root,COG3170@2|Bacteria,3TCIQ@508458|Synergistetes 508458|Synergistetes NU Tfp pilus assembly protein FimV - - - - - - - - - - - - - k59_45840_1 1121403.AUCV01000002_gene629 5.67e-33 126.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,42M7X@68525|delta/epsilon subdivisions,2WJCA@28221|Deltaproteobacteria,2MHKJ@213118|Desulfobacterales 28221|Deltaproteobacteria L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_45840_3 457405.FSDG_01580 4.42e-23 96.3 COG2963@1|root,COG2963@2|Bacteria,37CEX@32066|Fusobacteria 32066|Fusobacteria L transposase activity - - - - - - - - - - - - - k59_170350_1 1692249.A0A0K1RL40_9CIRC 7.64e-23 104.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_147349_1 679935.Alfi_0795 3.91e-43 145.0 2E6PI@1|root,3319W@2|Bacteria,4NSA1@976|Bacteroidetes,2FT5Y@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_71747_1 259536.Psyc_1441 1.94e-94 284.0 COG3258@1|root,COG3258@2|Bacteria,1NIQK@1224|Proteobacteria,1RYGP@1236|Gammaproteobacteria,3NQMG@468|Moraxellaceae 1236|Gammaproteobacteria C Cytochrome c - - 1.8.2.2 ko:K19713 - - - - ko00000,ko01000 - - - Cytochrome_CBB3 k59_245036_2 105154.Q9MBU3_9VIRU 1.67e-10 62.8 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_21005_2 999423.HMPREF9161_01433 4.45e-38 134.0 COG0615@1|root,COG0615@2|Bacteria,1UJSU@1239|Firmicutes,4H4AI@909932|Negativicutes 909932|Negativicutes H Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose hldE_2 - - - - - - - - - - - CTP_transf_like k59_104666_2 1288298.rosmuc_03782 2.74e-49 159.0 COG1396@1|root,COG1396@2|Bacteria,1N6V6@1224|Proteobacteria,2UGCV@28211|Alphaproteobacteria 28211|Alphaproteobacteria K transcriptional regulator - - - - - - - - - - - - HTH_19,HTH_3,HTH_31 k59_95848_1 186617.M9M8L2_9VIRU 1.54e-25 109.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_47390_1 1168281.I3PUX1_9CAUD 1.14e-18 86.7 4QBFN@10239|Viruses,4QXWN@35237|dsDNA viruses no RNA stage,4QPTW@28883|Caudovirales,4QNPZ@10744|Podoviridae 10744|Podoviridae S Phage stabilisation protein - - - - - - - - - - - - - k59_147358_1 1303692.SFUL_3690 8.68e-29 113.0 COG0338@1|root,COG0338@2|Bacteria,2IBJA@201174|Actinobacteria 201174|Actinobacteria L D12 class N6 adenine-specific DNA methyltransferase - - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 k59_195444_1 1048207.F8UBS2_9CAUD 1.04e-39 147.0 4QAIK@10239|Viruses 10239|Viruses S bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity - - - - - - - - - - - - - k59_6221_1 2003327.CAPSD_BPCHP 1.35e-44 162.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_147370_1 33876.JNXY01000004_gene1746 0.000399 48.9 COG1196@1|root,COG5412@1|root,COG1196@2|Bacteria,COG5412@2|Bacteria 2|Bacteria N phage tail tape measure protein - - - - - - - - - - - - Apolipoprotein,PhageMin_Tail,SLT k59_121999_1 1234888.K0A2J2_9VIRU 1.97e-39 146.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_6227_3 665942.HMPREF1022_03296 6.59e-07 49.7 2BG8R@1|root,32A5R@2|Bacteria,1Q8SQ@1224|Proteobacteria,433DN@68525|delta/epsilon subdivisions,2WY7Q@28221|Deltaproteobacteria,2MFMB@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_130470_1 1500301.JQMF01000006_gene1760 8.76e-29 115.0 COG0749@1|root,COG0749@2|Bacteria,1P27P@1224|Proteobacteria,2TVEI@28211|Alphaproteobacteria,4BIH2@82115|Rhizobiaceae 28211|Alphaproteobacteria L DNA polymerase A domain - - - - - - - - - - - - DNA_pol_A k59_130470_2 420324.KI911970_gene1445 7.58e-47 164.0 COG0258@1|root,COG0258@2|Bacteria,1MYSI@1224|Proteobacteria,2U60N@28211|Alphaproteobacteria 28211|Alphaproteobacteria L 5'-3' exonuclease, N-terminal resolvase-like domain - - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc_N k59_130470_3 1231336.L248_1682 4.74e-05 45.1 29YRS@1|root,30KMR@2|Bacteria,1U4VJ@1239|Firmicutes,4IEQD@91061|Bacilli,3FAVS@33958|Lactobacillaceae 91061|Bacilli S Protein of unknwon function (DUF3310) - - - - - - - - - - - - DUF3310 k59_73197_2 89187.ISM_05190 6.52e-23 97.8 COG5281@1|root,COG5281@2|Bacteria,1R47M@1224|Proteobacteria,2TUIV@28211|Alphaproteobacteria,46QA2@74030|Roseovarius 28211|Alphaproteobacteria S COG5281 Phage-related minor tail protein - - - - - - - - - - - - - k59_88068_2 1692257.A0A0K1RL39_9CIRC 5.9e-174 490.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_263925_1 1385658.U5KPZ6_9VIRU 5.21e-20 90.1 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_246247_1 1385935.N836_35780 1.28e-71 229.0 28JU3@1|root,2Z9J6@2|Bacteria,1GFAJ@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - k59_156425_1 105154.Q9MBU6_9VIRU 1.14e-103 320.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_163838_1 1537994.JQFW01000004_gene3265 1.36e-26 115.0 COG5281@1|root,COG5283@1|root,COG5281@2|Bacteria,COG5283@2|Bacteria,1QZAD@1224|Proteobacteria,1RYP3@1236|Gammaproteobacteria 1236|Gammaproteobacteria D nuclear chromosome segregation - - - - - - - - - - - - - k59_131596_1 1088721.NSU_0328 5.71e-22 92.8 2E3Y3@1|root,32YV3@2|Bacteria,1NC81@1224|Proteobacteria,2UI7M@28211|Alphaproteobacteria,2KAEM@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - k59_73203_1 145579.C_BPPHM 3.97e-31 111.0 4QCC5@10239|Viruses,4QUKW@29258|ssDNA viruses,4QP4C@10841|Microviridae 10841|Microviridae S viral process - - - - - - - - - - - - - k59_73203_3 145579.REP_BPPHM 9.37e-19 85.9 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_164030_1 279303.Q6J7X1_9CAUD 2.45e-91 285.0 4QCM9@10239|Viruses,4QVZV@35237|dsDNA viruses no RNA stage,4QTYN@28883|Caudovirales,4QMZ7@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_190052_2 1788454.A0A190WHE4_9CIRC 1.15e-18 92.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_74330_1 272134.KB731324_gene5337 1.43e-06 56.2 COG5283@1|root,COG5283@2|Bacteria,1GA9R@1117|Cyanobacteria,1HGXV@1150|Oscillatoriales 1117|Cyanobacteria S Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_82333_1 1122201.AUAZ01000017_gene2960 7.68e-184 526.0 COG5362@1|root,COG5362@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Terminase_6C k59_98153_1 1609634.A0A0C5ANA6_9VIRU 4.79e-13 73.2 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_247465_1 343516.Q287A3_9CAUD 1.66e-69 242.0 4QC24@10239|Viruses,4QZPR@35237|dsDNA viruses no RNA stage,4QRZK@28883|Caudovirales,4QP0N@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_198144_1 105154.Q9MBU6_9VIRU 5.43e-42 151.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_15647_1 1165094.RINTHH_3920 4.61e-30 117.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_106929_1 1618254.A0A0C5IBG4_9CIRC 5.59e-74 234.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_165301_1 1234888.K0A2J2_9VIRU 2.16e-63 213.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_89021_3 1618248.A0A0C5IB82_9CIRC 2.15e-57 189.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_182087_1 979535.F1D037_9CAUD 7.13e-09 63.9 4QASG@10239|Viruses,4QZZU@35237|dsDNA viruses no RNA stage,4QT37@28883|Caudovirales,4QNXD@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_24041_2 522373.Smlt1872 7.96e-19 87.0 COG5511@1|root,2ZER7@2|Bacteria,1RAE0@1224|Proteobacteria,1SEPD@1236|Gammaproteobacteria,1X6A6@135614|Xanthomonadales 135614|Xanthomonadales S Phage portal protein, lambda family - - - - - - - - - - - - - k59_165309_1 428125.CLOLEP_01417 1.46e-17 81.6 2CGG9@1|root,2ZVSJ@2|Bacteria,1V633@1239|Firmicutes,24HD0@186801|Clostridia,3WMXK@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_239213_1 444875.E3SMH6_9CAUD 2e-13 77.8 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QNBK@10744|Podoviridae 10744|Podoviridae S Ribonucleotide reductase, barrel domain - - - - - - - - - - - - - k59_265150_1 1385658.U5KNR1_9VIRU 1.61e-63 207.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_141048_12 1123508.JH636451_gene5927 8.69e-07 55.1 2DXPM@1|root,345W1@2|Bacteria,2J3SF@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - k59_174225_1 1379720.S5TNF0_9CIRC 1.41e-08 62.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_174225_2 1379725.S5SYG4_9CIRC 1.71e-12 73.2 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_83016_2 383372.Rcas_0202 2.75e-05 53.5 COG1216@1|root,COG1216@2|Bacteria,2GBIQ@200795|Chloroflexi,374ZU@32061|Chloroflexia 32061|Chloroflexia S PFAM glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 k59_165910_2 1379710.S5TNC2_9CIRC 5.37e-39 137.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_190823_4 186617.M9M8L2_9VIRU 1.09e-49 183.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_199_2 438482.A4ZRC7_9CAUD 5.31e-24 108.0 4QNBD@10744|Podoviridae 10744|Podoviridae S outer membrane - - - - - - - - - - - - - k59_41567_1 105154.Q9MBU3_9VIRU 1.81e-07 54.7 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_41567_2 105154.Q9MBU6_9VIRU 1.68e-167 493.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_207431_1 1120978.KB894081_gene93 3.15e-53 190.0 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,4H9Z7@91061|Bacilli,27FFC@186828|Carnobacteriaceae 91061|Bacilli L DNA polymerase family A - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_157648_1 1385658.U5KPZ6_9VIRU 1.16e-68 230.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_24999_7 440250.A5HL26_9CAUD 8.14e-28 119.0 4QBD3@10239|Viruses,4QXFU@35237|dsDNA viruses no RNA stage,4QQ7Z@28883|Caudovirales,4QNJ0@10744|Podoviridae 10744|Podoviridae S P22 coat protein - gene protein 5 - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0008150,GO:0009987,GO:0016032,GO:0016043,GO:0019012,GO:0019028,GO:0019030,GO:0019058,GO:0019068,GO:0019069,GO:0019075,GO:0022607,GO:0039620,GO:0042802,GO:0042803,GO:0044085,GO:0044403,GO:0044419,GO:0044423,GO:0046729,GO:0046797,GO:0046983,GO:0051704,GO:0071840 - - - - - - - - - - - k59_124477_2 1234888.K0A2J2_9VIRU 1.8e-62 213.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_41570_1 105154.Q9MBU3_9VIRU 2.32e-10 64.3 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_182528_6 1219035.NT2_13_00580 5.54e-42 157.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_257194_1 742725.HMPREF9450_02130 1.53e-24 98.6 2DNV9@1|root,32ZB3@2|Bacteria,4NV7Y@976|Bacteroidetes,2FTAS@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_232405_1 1692244.A0A0K1RLR5_9CIRC 1.01e-23 102.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_16730_1 349102.Rsph17025_0443 2.66e-27 118.0 2DKW9@1|root,30JFD@2|Bacteria,1QZ8U@1224|Proteobacteria,2U83R@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_249593_2 1536770.R50345_29865 1.5e-08 58.5 COG1876@1|root,COG1876@2|Bacteria,1V3PP@1239|Firmicutes,4HE9P@91061|Bacilli,26RR8@186822|Paenibacillaceae 91061|Bacilli M D-alanyl-D-alanine carboxypeptidase vanY_1 - 3.4.17.14 ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 M00651 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 - - - VanY k59_241288_1 1273711.A0A096VKF5_9CAUD 1.07e-38 151.0 4QCM5@10239|Viruses,4QVZY@35237|dsDNA viruses no RNA stage,4QQFH@28883|Caudovirales,4QNDH@10744|Podoviridae 10744|Podoviridae S Bacteriophage head to tail connecting protein - GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019028,GO:0019058,GO:0019068,GO:0019072,GO:0019073,GO:0032991,GO:0044403,GO:0044419,GO:0044423,GO:0046798,GO:0051704 - - - - - - - - - - - k59_67165_4 1379281.AVAG01000008_gene1401 0.000758 50.8 COG0621@1|root,COG3551@1|root,COG0621@2|Bacteria,COG3551@2|Bacteria,1RB2G@1224|Proteobacteria,42UMV@68525|delta/epsilon subdivisions,2WR43@28221|Deltaproteobacteria,2MDHR@213115|Desulfovibrionales 28221|Deltaproteobacteria J Sulfotransferase family - - - - - - - - - - - - - k59_67165_16 202954.BBNK01000034_gene3794 1.57e-38 133.0 2A3Q7@1|root,30S7S@2|Bacteria,1NP2K@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_67165_23 926550.CLDAP_14930 5.68e-26 102.0 COG0629@1|root,COG0629@2|Bacteria,2G6YE@200795|Chloroflexi 200795|Chloroflexi L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism - - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_75590_2 1156919.QWC_17152 2.94e-07 52.4 COG3772@1|root,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,2VTZX@28216|Betaproteobacteria,3T4AD@506|Alcaligenaceae 28216|Betaproteobacteria G lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_199848_1 948071.S4S2D9_9CAUD 1.33e-65 219.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QNQ6@10744|Podoviridae 10744|Podoviridae S ribonucleoside-triphosphate reductase activity - - - - - - - - - - - - - k59_58897_2 105154.Q9MBU6_9VIRU 3.99e-197 568.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_58897_4 1165094.RINTHH_3920 1.65e-75 240.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_191485_2 373406.Q1A023_9CAUD 5.27e-38 145.0 4QBP9@10239|Viruses,4QPQF@28883|Caudovirales,4QMF3@10699|Siphoviridae 10699|Siphoviridae S Domain of unknown function (DUF932) - - - - - - - - - - - - - k59_142614_2 1609634.A0A0C5AFV4_9VIRU 9.72e-86 271.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_191929_1 1120983.KB894570_gene1694 1.5e-13 70.9 COG0582@1|root,COG0582@2|Bacteria,1N59J@1224|Proteobacteria,2UD0G@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_integrase k59_191929_2 438753.AZC_3607 7.4e-59 211.0 COG5108@1|root,COG5108@2|Bacteria,1PIWB@1224|Proteobacteria,2U1JR@28211|Alphaproteobacteria 28211|Alphaproteobacteria K DNA-dependent RNA polymerase - - - - - - - - - - - - RNA_pol,RPOL_N k59_9559_3 1168281.I3PUY1_9CAUD 4.93e-07 51.2 4QG00@10239|Viruses,4QZDS@35237|dsDNA viruses no RNA stage,4QTM4@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_26622_1 1385658.U5KPZ6_9VIRU 1.22e-58 201.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_241857_2 877418.ATWV01000006_gene2098 5.49e-05 50.8 COG3864@1|root,COG3864@2|Bacteria,2J6M4@203691|Spirochaetes 203691|Spirochaetes S VWA-like domain (DUF2201) - - - - - - - - - - - - DUF2201,DUF2201_N k59_167473_6 1234664.AMRO01000024_gene1822 6.64e-13 77.4 28K55@1|root,2Z9TX@2|Bacteria,1V0P7@1239|Firmicutes,4HEFY@91061|Bacilli,1WEQM@129337|Geobacillus 91061|Bacilli S Siphovirus ReqiPepy6 Gp37-like protein - - - - - - - - - - - - Sipho_Gp37 k59_67901_2 105154.Q9MBT9_9VIRU 8.65e-11 60.1 4QCC5@10239|Viruses,4QUKW@29258|ssDNA viruses,4QP4C@10841|Microviridae 10841|Microviridae S viral process - - - - - - - - - - - - - k59_76200_2 102125.Xen7305DRAFT_00036340 3.27e-16 81.3 2DKXV@1|root,30THP@2|Bacteria,1GQMH@1117|Cyanobacteria 1117|Cyanobacteria S Sulfotransferase family - - - - - - - - - - - - Sulfotransfer_2 k59_175338_1 1788452.A0A190WHG0_9CIRC 1.97e-27 110.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_200408_2 1234888.K0A2R8_9VIRU 5.78e-23 97.1 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_241865_2 909943.HIMB100_00006080 8.87e-06 55.1 COG0582@1|root,COG0582@2|Bacteria,1PTZ1@1224|Proteobacteria,2U1YG@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_integrase k59_1765_3 546264.NEIFLAOT_00952 9.54e-44 158.0 COG4128@1|root,COG4128@2|Bacteria,1R51Y@1224|Proteobacteria,2VIPX@28216|Betaproteobacteria,2KRCQ@206351|Neisseriales 206351|Neisseriales S Zonular occludens toxin (Zot) - - - ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko02042 - - - Zot k59_191935_2 1235689.K4NYY6_9CAUD 2.56e-18 83.2 4QGFZ@10239|Viruses,4QVJ7@35237|dsDNA viruses no RNA stage,4QU5D@28883|Caudovirales,4QNJN@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_109264_1 1618254.A0A0C5IBG4_9CIRC 1.51e-152 432.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_142681_1 1088721.NSU_0291 1.15e-160 462.0 COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,2TQWC@28211|Alphaproteobacteria,2KBNR@204457|Sphingomonadales 204457|Sphingomonadales L UvrD-like helicase C-terminal domain - - - - - - - - - - - - AAA_30,UvrD_C_2 k59_10157_3 759938.F5BSB4_9CIRC 0.00012 48.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_109946_2 195105.CN97_04315 4.35e-06 53.1 COG3740@1|root,COG3740@2|Bacteria,1N2D8@1224|Proteobacteria,2UD3U@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Phage prohead protease, HK97 family - - - ko:K06904 - - - - ko00000 - - - Peptidase_S78 k59_201102_2 985255.APHJ01000039_gene152 1.4e-19 84.0 2C8RN@1|root,32RMQ@2|Bacteria,4NSD0@976|Bacteroidetes,1I3WH@117743|Flavobacteriia,2P70C@244698|Gillisia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_27326_1 1000565.METUNv1_01679 1.79e-48 175.0 COG3941@1|root,COG5281@1|root,COG3941@2|Bacteria,COG5281@2|Bacteria,1MZWI@1224|Proteobacteria 1224|Proteobacteria D Mu-like prophage protein - - - - - - - - - - - - Tape_meas_lam_C k59_2535_2 1492922.GY26_15975 6.26e-07 53.5 COG1196@1|root,COG1511@1|root,COG1196@2|Bacteria,COG1511@2|Bacteria 2|Bacteria Q domain protein - - - ko:K02666 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - DUF349 k59_84636_24 1236573.K4LRR0_9CAUD 2.4e-10 66.6 4QBFR@10239|Viruses,4QV1E@35237|dsDNA viruses no RNA stage,4QPRX@28883|Caudovirales,4QKMP@10699|Siphoviridae 10699|Siphoviridae S ERF superfamily - - - - - - - - - - - - - k59_10236_1 572265.HDEF_1701 6.19e-35 124.0 2AD08@1|root,312N7@2|Bacteria,1NDC4@1224|Proteobacteria,1SAPT@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Holin of 3TMs, for gene-transfer release - - - - - - - - - - - - GTA_holin_3TM k59_10236_2 1280953.HOC_08107 7.75e-06 48.1 COG3108@1|root,COG3108@2|Bacteria,1NMU6@1224|Proteobacteria,2UJD2@28211|Alphaproteobacteria,43YD7@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Peptidase M15 - - - - - - - - - - - - Peptidase_M15_3 k59_126939_1 1234888.K0A2J2_9VIRU 3.8e-64 215.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_18366_2 105154.Q9MBU6_9VIRU 2.14e-106 325.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_226285_1 1618247.A0A0C5IMK7_9CIRC 6.01e-10 65.1 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_209160_8 181604.Q8W6D1_9VIRU 5.2e-16 74.7 4QGF7@10239|Viruses,4QUKH@29258|ssDNA viruses,4QP4F@10860|Inoviridae 10860|Inoviridae S Protein of unknown function (DUF2523) - - - - - - - - - - - - - k59_209160_9 1129374.AJE_00725 4.42e-60 206.0 COG4128@1|root,COG4128@2|Bacteria,1RK87@1224|Proteobacteria,1SYAX@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Zonular occludens toxin (Zot) - - - ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko02042 - - - Zot k59_93585_1 105154.Q9MBU6_9VIRU 4.04e-79 252.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_93585_3 105154.Q9MBU3_9VIRU 6.67e-19 84.0 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_35683_1 1379695.S5SXZ1_9CIRC 4.1e-27 122.0 4QD5V@10239|Viruses 10239|Viruses S Viral coat protein (S domain) - GO:0003674,GO:0003676,GO:0003723,GO:0005198,GO:0005488,GO:0005509,GO:0005575,GO:0008289,GO:0019012,GO:0019028,GO:0019030,GO:0039617,GO:0039660,GO:0043167,GO:0043169,GO:0044423,GO:0046872,GO:0097159,GO:1901363 - - - - - - - - - - - k59_35683_2 1676184.A0A186YBN5_9CIRC 2.39e-10 65.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_35683_3 1574422.A0A0A1ENW9_9CIRC 3.11e-34 132.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_218880_1 1304877.KI519399_gene4996 3.93e-48 174.0 COG0454@1|root,COG0827@1|root,COG1203@1|root,COG0456@2|Bacteria,COG0827@2|Bacteria,COG1203@2|Bacteria,1QZ6D@1224|Proteobacteria,2U5JW@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DNA restriction-modification system - - - - - - - - - - - - AAA_34 k59_10553_1 1172188.KB911820_gene2885 1.7e-164 485.0 COG0209@1|root,COG0209@2|Bacteria,2IC1H@201174|Actinobacteria 201174|Actinobacteria F Ribonucleotide reductase, barrel domain - - - - - - - - - - - - Ribonuc_red_lgC k59_127432_1 1692242.A0A0K1RKZ2_9CIRC 2.32e-35 135.0 4QFEW@10239|Viruses,4QUKZ@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_77472_1 1234888.K0A2J2_9VIRU 4.92e-32 127.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_135599_1 1198452.Jab_2c20470 6.8e-33 124.0 COG0582@1|root,COG0582@2|Bacteria,1MXUB@1224|Proteobacteria,2VPGU@28216|Betaproteobacteria,478A2@75682|Oxalobacteraceae 28216|Betaproteobacteria L Phage integrase, N-terminal - - - - - - - - - - - - Integrase_1,Phage_int_SAM_2 k59_10660_1 1618258.A0A0C5I9K3_9CIRC 3.58e-14 79.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_18834_1 69279.BG36_20875 8.28e-97 298.0 COG1783@1|root,COG4373@1|root,COG1783@2|Bacteria,COG4373@2|Bacteria,1PE12@1224|Proteobacteria,2V9EC@28211|Alphaproteobacteria,43QJZ@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Mu-like prophage FluMu protein gp28 - - - - - - - - - - - - - k59_3126_1 84751.XP_007878337.1 5.61e-16 84.7 COG1061@1|root,2QT4U@2759|Eukaryota,38GE0@33154|Opisthokonta,3NWXY@4751|Fungi,3UZD8@5204|Basidiomycota,3MYT9@452284|Ustilaginomycotina 4751|Fungi A Type III restriction enzyme, res subunit irc3 GO:0000002,GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005739,GO:0005759,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0007005,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010467,GO:0010501,GO:0016043,GO:0016070,GO:0016072,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022613,GO:0031974,GO:0031981,GO:0032042,GO:0033676,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042623,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070035,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 - ko:K17677 - - - - ko00000,ko01000,ko03029 - - - Helicase_C,ResIII k59_35777_1 626418.bglu_1g20910 1.56e-63 206.0 28KIJ@1|root,2ZA3S@2|Bacteria,1R4PD@1224|Proteobacteria,2VP07@28216|Betaproteobacteria,1KBS4@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_27991_1 342610.Patl_3555 6.6e-19 85.9 COG0741@1|root,COG0741@2|Bacteria,1QZ7X@1224|Proteobacteria,1T417@1236|Gammaproteobacteria 1236|Gammaproteobacteria M lytic transglycosylase activity - - - - - - - - - - - - - k59_260090_1 759938.F5BSB4_9CIRC 2.08e-34 138.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_192939_2 1618247.A0A0C5IMK7_9CIRC 0.000865 44.7 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_209515_3 105154.Q9MBU6_9VIRU 6.79e-218 621.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_209515_4 105154.Q9MBU3_9VIRU 5.24e-18 86.7 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_226689_1 488538.SAR116_0386 2.05e-55 182.0 COG1351@1|root,COG1351@2|Bacteria,1MWY8@1224|Proteobacteria,2TTER@28211|Alphaproteobacteria,4BRKK@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant thyX - 2.1.1.148 ko:K03465 ko00240,ko00670,ko01100,map00240,map00670,map01100 - R06613 RC00022,RC00332 ko00000,ko00001,ko01000 - - - Thy1 k59_60444_2 665956.HMPREF1032_00674 1.84e-49 171.0 28J3N@1|root,2Z8ZU@2|Bacteria,1V15Z@1239|Firmicutes,249Z0@186801|Clostridia,3WNJZ@541000|Ruminococcaceae 186801|Clostridia S Phage portal protein - - - - - - - - - - - - Phage_portal k59_18839_2 1121921.KB898717_gene3445 8.13e-17 84.7 COG5527@1|root,COG5527@2|Bacteria,1R7A6@1224|Proteobacteria,1RQMU@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Protein involved in initiation of plasmid replication repA - - - - - - - - - - - Rep_3 k59_69374_1 1385658.U5KPZ6_9VIRU 6.17e-141 420.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_69374_4 1165094.RINTHH_3920 6.29e-35 134.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_60699_1 1452718.JBOY01000021_gene715 1.8e-26 107.0 COG0553@1|root,COG0553@2|Bacteria 2|Bacteria L helicase activity - - - - - - - - - - - - Helicase_C,SNF2_N k59_36077_1 411473.RUMCAL_00893 2.26e-10 61.2 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,3WH0A@541000|Ruminococcaceae 186801|Clostridia L helicase - - - - - - - - - - - - Helicase_C,SNF2_N k59_160417_1 1206731.BAGB01000013_gene2363 3.98e-45 161.0 COG0438@1|root,COG0438@2|Bacteria,2HPJ5@201174|Actinobacteria,4G5MD@85025|Nocardiaceae 201174|Actinobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glycos_transf_1 k59_160420_1 1094560.ME9_00989 1.61e-07 56.6 COG3756@1|root,COG3756@2|Bacteria,1P6UX@1224|Proteobacteria,2UC8G@28211|Alphaproteobacteria,48UNA@772|Bartonellaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF1376) - - - - - - - - - - - - DUF1376 k59_234675_2 1122218.KB893668_gene2912 0.000227 52.8 COG1511@1|root,COG5283@1|root,COG1511@2|Bacteria,COG5283@2|Bacteria,1PGM4@1224|Proteobacteria,2V9RM@28211|Alphaproteobacteria,1JYSQ@119045|Methylobacteriaceae 28211|Alphaproteobacteria S domain protein - - - - - - - - - - - - - k59_144645_1 478749.BRYFOR_08561 2.31e-26 105.0 2BPMG@1|root,32IEH@2|Bacteria,1V9DC@1239|Firmicutes,24MC0@186801|Clostridia 186801|Clostridia S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - - k59_219557_1 1234888.K0A2J2_9VIRU 1.34e-51 181.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_77887_1 439235.Dalk_3293 4.1e-21 97.1 COG1061@1|root,COG1061@2|Bacteria,1QWMJ@1224|Proteobacteria,42NXF@68525|delta/epsilon subdivisions,2WJWA@28221|Deltaproteobacteria,2MHPY@213118|Desulfobacterales 28221|Deltaproteobacteria L type III restriction protein res subunit - - - - - - - - - - - - Helicase_C,ResIII k59_251358_1 1287276.X752_18575 3.56e-31 122.0 2BZ9Z@1|root,2Z97E@2|Bacteria,1RD7Q@1224|Proteobacteria,2U775@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_44644_3 1003200.AXXA_03459 1.36e-54 185.0 COG3409@1|root,COG3409@2|Bacteria,1RAYU@1224|Proteobacteria,2VPG4@28216|Betaproteobacteria 28216|Betaproteobacteria M N-acetylmuramidase - - - - - - - - - - - - Muraidase,PG_binding_1 k59_193840_1 1197951.I6S2A3_9CAUD 4.36e-25 104.0 4QAIV@10239|Viruses,4QYFZ@35237|dsDNA viruses no RNA stage,4QQUY@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_85780_1 1609634.A0A0C5AFV4_9VIRU 3.16e-120 362.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_251900_1 145579.REP_BPPHM 1.05e-53 181.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_103027_2 1034115.G1D5E6_9CAUD 2.42e-30 117.0 4QE8A@10239|Viruses,4QXTV@35237|dsDNA viruses no RNA stage,4QS6D@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_145337_2 866895.HBHAL_2436 4.15e-18 90.5 COG0438@1|root,COG2520@1|root,COG0438@2|Bacteria,COG2520@2|Bacteria,1U9Z2@1239|Firmicutes,4HEVV@91061|Bacilli 91061|Bacilli M Glycosyl transferases group 1 - - - - - - - - - - - - Glycos_transf_1,Glycos_transf_2,Methyltransf_21 k59_145337_3 796606.BMMGA3_10640 5.07e-07 56.6 COG2120@1|root,COG2120@2|Bacteria,1TV10@1239|Firmicutes,4HFJQ@91061|Bacilli,1ZAZI@1386|Bacillus 91061|Bacilli S proteins, LmbE homologs ypjG - - ko:K01463 - - - - ko00000,ko01000 - - - PIG-L k59_53779_2 1519439.JPJG01000072_gene1341 2.67e-05 47.8 COG1476@1|root,COG1476@2|Bacteria,1V36C@1239|Firmicutes,24933@186801|Clostridia,2N8XC@216572|Oscillospiraceae 186801|Clostridia K Bacteriophage CI repressor helix-turn-helix domain - - - - - - - - - - - - HTH_3 k59_53779_3 573413.Spirs_1973 5.9e-15 76.6 COG3723@1|root,COG3723@2|Bacteria,2JADR@203691|Spirochaetes 2|Bacteria L PFAM DNA single-strand annealing protein RecT-like bet - - ko:K07455 - - - - ko00000,ko03400 - - - RecT k59_69995_1 1556290.A0A0A0RM00_9CAUD 4.13e-58 199.0 4QAXQ@10239|Viruses,4QRFY@28883|Caudovirales,4QM52@10699|Siphoviridae 10699|Siphoviridae S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor - - - - - - - - - - - - - k59_94474_2 138119.DSY0667 3.99e-14 75.5 COG0524@1|root,COG3613@1|root,COG0524@2|Bacteria,COG3613@2|Bacteria 2|Bacteria F nucleoside 2-deoxyribosyltransferase gsk GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008906,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237 2.4.2.6,2.7.1.73,2.7.1.92 ko:K00892,ko:K03338,ko:K08728 ko00230,ko00240,ko00562,ko01100,ko01120,map00230,map00240,map00562,map01100,map01120 - R01131,R01228,R02806,R05661 RC00002,RC00017,RC00063 ko00000,ko00001,ko01000 - - iSDY_1059.SDY_0442 Nuc_deoxyrib_tr,PfkB k59_94474_3 1038858.AXBA01000001_gene3356 3e-08 61.2 COG1028@1|root,COG1028@2|Bacteria,1MU73@1224|Proteobacteria,2TQRG@28211|Alphaproteobacteria 28211|Alphaproteobacteria IQ reductase - - - - - - - - - - - - adh_short_C2 k59_94474_5 1266914.ATUK01000013_gene1893 4.53e-10 68.2 COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,1WXIX@135613|Chromatiales 135613|Chromatiales E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily - - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k59_94474_7 1498011.A0A096XUU8_9CAUD 3.82e-88 263.0 4QARC@10239|Viruses,4QPDS@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_202774_1 1165094.RINTHH_3920 9.47e-21 92.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_11539_2 691965.D4P7L7_9CAUD 1.04e-160 488.0 4QB9J@10239|Viruses,4QXFE@35237|dsDNA viruses no RNA stage,4QS1Z@28883|Caudovirales,4QN8F@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_227809_3 1609634.A0A0C5AFV4_9VIRU 2.88e-123 373.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_78425_11 348824.LPU83_1746 1.71e-69 239.0 COG0749@1|root,COG0749@2|Bacteria,1MWX7@1224|Proteobacteria,2UNT9@28211|Alphaproteobacteria,4BJFM@82115|Rhizobiaceae 28211|Alphaproteobacteria L COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A,DNA_pol_A_exo1 k59_170012_1 1379722.S5SY31_9CIRC 4.22e-07 52.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_120212_1 1034115.G1D5L0_9CAUD 5.26e-32 121.0 4QCF5@10239|Viruses,4QV2A@35237|dsDNA viruses no RNA stage,4QPJI@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_45707_7 1498011.A0A096XUW0_9CAUD 1.71e-30 117.0 4QF7M@10239|Viruses,4QSE1@28883|Caudovirales 28883|Caudovirales S AAA domain - - - - - - - - - - - - - k59_54106_2 145579.REP_BPPHM 2.83e-13 73.6 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_70276_1 398578.Daci_2097 1.5e-27 111.0 COG4128@1|root,COG4128@2|Bacteria,1R51Y@1224|Proteobacteria,2VIPX@28216|Betaproteobacteria,4AFJF@80864|Comamonadaceae 28216|Betaproteobacteria S Zonular occludens toxin (Zot) - - - ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko02042 - - - Zot k59_70276_10 399795.CtesDRAFT_PD4232 1.01e-14 79.7 COG0464@1|root,COG0464@2|Bacteria,1QU82@1224|Proteobacteria,2WHSD@28216|Betaproteobacteria 28216|Betaproteobacteria O PFAM Zonular occludens toxin - - - ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko02042 - - - Zot k59_186503_3 1229760.K4IBY8_9CAUD 1.45e-25 108.0 4QBFR@10239|Viruses,4QV1E@35237|dsDNA viruses no RNA stage,4QPRX@28883|Caudovirales,4QICS@10662|Myoviridae 10662|Myoviridae S ERF superfamily - - - - - - - - - - - - - k59_12002_1 1453496.AT03_12665 3.38e-29 116.0 COG3969@1|root,COG3969@2|Bacteria,1NBDM@1224|Proteobacteria,1RYRP@1236|Gammaproteobacteria 1236|Gammaproteobacteria S phosphoadenosine phosphosulfate ybdN - - - - - - - - - - - DUF3440,PAPS_reduct k59_12002_3 1486472.A0A068F3J9_9CAUD 3.43e-54 181.0 4QBNM@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales 28883|Caudovirales S N-methyltransferase activity - - - - - - - - - - - - - k59_54215_2 1609634.A0A0C5AFT2_9VIRU 1.64e-101 305.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_194247_1 1234888.K0A2J2_9VIRU 1.15e-48 174.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_228138_1 1121129.KB903359_gene1821 1.91e-15 80.9 COG0305@1|root,COG0305@2|Bacteria,4NF8P@976|Bacteroidetes,2FNG7@200643|Bacteroidia,22XCZ@171551|Porphyromonadaceae 976|Bacteroidetes L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_145844_1 2003327.CAPSD_BPCHP 1.15e-26 108.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_154009_2 1128111.HMPREF0870_01778 8.08e-06 48.1 2E38J@1|root,32Y88@2|Bacteria,1VAXK@1239|Firmicutes,4H5UC@909932|Negativicutes 909932|Negativicutes S VRR_NUC - - - - - - - - - - - - VRR_NUC k59_178428_1 1609634.A0A0C5AFV4_9VIRU 1.01e-69 226.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_221068_5 1385658.U5KNR1_9VIRU 2.02e-67 219.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_146142_1 1165094.RINTHH_3920 3.06e-65 214.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_170828_1 1298867.AUES01000015_gene3811 7.87e-67 216.0 COG0451@1|root,COG0451@2|Bacteria,1QUEV@1224|Proteobacteria,2TW46@28211|Alphaproteobacteria,3JUU7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Male sterility protein - - 4.2.1.46,5.1.3.2 ko:K01710,ko:K01784 ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130 M00361,M00362,M00632,M00793 R00291,R02984,R06513 RC00289,RC00402 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd k59_120979_1 509191.AEDB02000096_gene3491 2.45e-17 85.9 arCOG06858@1|root,2ZAA2@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_61843_2 1795995.A0A140CTL4_9CIRC 7.91e-13 72.0 4QHFI@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_29796_1 1458848.X2KMJ3_9CAUD 8.36e-10 59.3 4QBYE@10239|Viruses,4QVYH@35237|dsDNA viruses no RNA stage,4QQTP@28883|Caudovirales,4QP46@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_29796_2 1051675.G0YQH4_9CAUD 3.57e-27 121.0 4QE55@10239|Viruses,4QSGR@28883|Caudovirales,4QNIB@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_178610_1 1618247.A0A0C5IMK7_9CIRC 5.25e-09 62.0 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_137435_1 1288298.rosmuc_03783 8.8e-100 305.0 COG0582@1|root,COG0582@2|Bacteria,1N59J@1224|Proteobacteria,2UD0G@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_integrase k59_137435_3 1028800.RG540_CH13580 3.95e-83 285.0 COG5108@1|root,COG5108@2|Bacteria,1PIWB@1224|Proteobacteria,2U1JR@28211|Alphaproteobacteria,4BC0X@82115|Rhizobiaceae 28211|Alphaproteobacteria K DNA-directed RNA polymerase N-terminal - - - - - - - - - - - - RNA_pol,RPOL_N k59_20566_1 2003327.CAPSD_BPCHP 3.93e-49 174.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_54725_1 1168059.KB899087_gene1226 1.36e-05 53.5 COG0863@1|root,COG0863@2|Bacteria,1MY4G@1224|Proteobacteria,2U1X0@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.113 ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_194922_1 1540097.A0A0A0YPX0_9CAUD 1.57e-68 222.0 4QEG2@10239|Viruses,4QRJ9@28883|Caudovirales,4QP0R@10744|Podoviridae 10744|Podoviridae S exonuclease activity - - - - - - - - - - - - - k59_62103_1 1088864.G8IEB8_9CAUD 4.49e-06 51.2 4QH44@10239|Viruses,4QZ61@35237|dsDNA viruses no RNA stage,4QQH2@28883|Caudovirales,4QM4C@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_62103_4 1264700.L0MY07_9CAUD 8.49e-16 75.5 4QEGD@10239|Viruses,4QVU1@35237|dsDNA viruses no RNA stage,4QPN9@28883|Caudovirales,4QJCM@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_146644_1 1410624.JNKK01000017_gene1975 4.04e-21 99.4 COG4695@1|root,COG4695@2|Bacteria,1TP8B@1239|Firmicutes,2497C@186801|Clostridia,27I52@186928|unclassified Lachnospiraceae 186801|Clostridia S Phage portal protein - - - - - - - - - - - - Phage_portal k59_162017_2 1120936.KB907208_gene1181 3.1e-21 88.6 2B7G5@1|root,320K0@2|Bacteria,2GUCA@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_30156_1 1220601.L7TLU4_9CAUD 7.53e-33 124.0 4QAM2@10239|Viruses,4QV3W@35237|dsDNA viruses no RNA stage,4QPGK@28883|Caudovirales 28883|Caudovirales S catalytic activity - GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004521,GO:0004523,GO:0004527,GO:0004536,GO:0004540,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008409,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016888,GO:0016891,GO:0016893,GO:0017108,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048256,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140097,GO:0140098,GO:1901360 - - - - - - - - - - - k59_121336_1 1510531.JQJJ01000011_gene2921 5.79e-46 164.0 COG0553@1|root,COG0553@2|Bacteria,1R7CK@1224|Proteobacteria,2U228@28211|Alphaproteobacteria,3JXBV@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L DNA methylase N-4 - - - - - - - - - - - - Helicase_C,N6_N4_Mtase k59_86782_2 105154.Q9MBU6_9VIRU 8.16e-45 159.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_121341_1 187764.Q8SCG7_9CAUD 1e-07 58.5 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales,4QNBW@10744|Podoviridae 10744|Podoviridae S DNA helicase activity - - - - - - - - - - - - - k59_154497_1 1121422.AUMW01000021_gene1621 6.07e-05 48.9 COG3108@1|root,COG3409@1|root,COG3108@2|Bacteria,COG3409@2|Bacteria 2|Bacteria M Peptidoglycan-binding domain 1 protein - - 3.4.17.14 ko:K08640 - - - - ko00000,ko01000,ko01002,ko01011 - - - PG_binding_1,Peptidase_M15_3,Transglycosylas k59_154497_2 1173023.KE650771_gene5116 2.29e-11 66.2 COG0642@1|root,COG0784@1|root,COG2199@1|root,COG2202@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,1G09B@1117|Cyanobacteria 1117|Cyanobacteria T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - GAF,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg k59_221753_2 10658.DPOL_BPPRD 5.53e-32 126.0 4QAWD@10239|Viruses,4QVNG@35237|dsDNA viruses no RNA stage,4QHTW@10656|Tectiviridae 10656|Tectiviridae L DNA binding - GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_204232_3 49964.Q94MR7_9CAUD 1.09e-93 303.0 4QERB@10239|Viruses,4R014@35237|dsDNA viruses no RNA stage,4QTGJ@28883|Caudovirales,4QNZG@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_253125_2 1379725.S5TMY9_9CIRC 6.92e-37 141.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_62263_1 490913.C4NTD6_9CAUD 6.37e-18 80.9 4QEMD@10239|Viruses,4R0JN@35237|dsDNA viruses no RNA stage,4QUGF@28883|Caudovirales,4QNXF@10744|Podoviridae 10744|Podoviridae S AAA domain - - - - - - - - - - - - - k59_62263_2 490913.C4NTD7_9CAUD 2.7e-128 372.0 4QD9V@10239|Viruses,4QYQ1@35237|dsDNA viruses no RNA stage,4QTHS@28883|Caudovirales,4QP1H@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_62263_3 1477404.A0A023NH85_9CAUD 1.04e-79 248.0 4QDJJ@10239|Viruses,4QYWQ@35237|dsDNA viruses no RNA stage,4QTQX@28883|Caudovirales,4QP11@10744|Podoviridae 10744|Podoviridae S magnesium ion binding - - - - - - - - - - - - - k59_30354_1 1122201.AUAZ01000017_gene2948 3.5e-46 168.0 COG0507@1|root,COG0507@2|Bacteria,1QFB2@1224|Proteobacteria,1SE0Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria L AAA domain - - - - - - - - - - - - AAA_30,UvrD_C_2,Viral_helicase1 k59_137986_4 742733.HMPREF9469_05066 7.24e-24 102.0 2EWZQ@1|root,33QB0@2|Bacteria,1V0T1@1239|Firmicutes,249Z2@186801|Clostridia,221YV@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_95565_1 478749.BRYFOR_08565 5.84e-19 86.7 2A0KC@1|root,2ZGJK@2|Bacteria,1V2JS@1239|Firmicutes,24H6R@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_221824_3 105154.Q9MBU6_9VIRU 1.56e-09 58.5 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_187556_1 1121448.DGI_2053 7.28e-53 180.0 COG4653@1|root,COG4653@2|Bacteria,1MXMN@1224|Proteobacteria,42UKA@68525|delta/epsilon subdivisions,2WQZV@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Phage capsid family - - - - - - - - - - - - Phage_capsid k59_211521_2 1121935.AQXX01000130_gene2425 3.44e-23 95.1 2AD08@1|root,312N7@2|Bacteria,1NDC4@1224|Proteobacteria,1SAPT@1236|Gammaproteobacteria,1XQHK@135619|Oceanospirillales 135619|Oceanospirillales S Holin of 3TMs, for gene-transfer release - - - - - - - - - - - - GTA_holin_3TM k59_79498_1 869209.Tresu_0626 1.4e-05 52.0 COG0740@1|root,COG0740@2|Bacteria,2J78H@203691|Spirochaetes 203691|Spirochaetes OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins clpP-2 - 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease k59_187565_1 1121033.AUCF01000008_gene5755 8.13e-31 114.0 28NA5@1|root,2ZBDZ@2|Bacteria,1MXY5@1224|Proteobacteria,2TYZX@28211|Alphaproteobacteria,2JWWC@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - k59_187565_2 1121033.AUCF01000004_gene4990 5e-13 70.9 COG0811@1|root,COG0811@2|Bacteria,1PPAP@1224|Proteobacteria,2TS0F@28211|Alphaproteobacteria,2JUNK@204441|Rhodospirillales 204441|Rhodospirillales U MotA/TolQ/ExbB proton channel family - - - - - - - - - - - - MotA_ExbB k59_5945_1 1618248.A0A0C5IB82_9CIRC 7.13e-22 100.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_154863_1 1144313.PMI10_00628 2.8e-22 99.8 COG0553@1|root,COG0863@1|root,COG0553@2|Bacteria,COG0863@2|Bacteria,4NHHF@976|Bacteroidetes,1I7WE@117743|Flavobacteriia 976|Bacteroidetes L DNA methylase - - - - - - - - - - - - Helicase_C,N6_N4_Mtase,SNF2_N k59_222000_2 1234888.K0A2J2_9VIRU 2.04e-127 385.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_262383_1 1618247.A0A0C5IMK7_9CIRC 1.26e-14 78.6 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_262383_2 1618257.A0A0C5IBI9_9CIRC 1.68e-50 168.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_5950_1 156889.Mmc1_1690 5.61e-23 101.0 COG1783@1|root,COG1783@2|Bacteria,1MVJB@1224|Proteobacteria,2U2BM@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6 k59_79591_4 869724.H6BI57_9CAUD 3.29e-46 173.0 4QBYN@10239|Viruses,4QZT8@35237|dsDNA viruses no RNA stage,4QR5G@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_13021_1 1278073.MYSTI_01963 3.57e-39 162.0 COG0749@1|root,COG0749@2|Bacteria,1MWX7@1224|Proteobacteria 1224|Proteobacteria L COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A,DNA_pol_A_exo1 k59_55174_1 438753.AZC_3583 8.58e-32 130.0 28IA2@1|root,2Z8CQ@2|Bacteria,1PQM2@1224|Proteobacteria,2TUAP@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_222018_2 1282876.BAOK01000002_gene600 1.43e-25 107.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2TS19@28211|Alphaproteobacteria,4BP86@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdZ - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_lgC,Ribonuc_red_lgN k59_171489_3 420324.KI911948_gene9340 1.36e-27 110.0 2D0K9@1|root,32T8S@2|Bacteria,1MZRW@1224|Proteobacteria,2UDZH@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_204425_1 55207.KP22_06600 8.78e-34 126.0 COG4388@1|root,COG4388@2|Bacteria,1R5B8@1224|Proteobacteria,1RQUT@1236|Gammaproteobacteria,1MTKY@122277|Pectobacterium 1236|Gammaproteobacteria - - - - - - - - - - - - - - Mu-like_Pro k59_204425_2 1044.EH31_05480 1.23e-06 48.9 COG1396@1|root,COG1396@2|Bacteria,1NGM7@1224|Proteobacteria,2UG4Y@28211|Alphaproteobacteria,2K86Q@204457|Sphingomonadales 204457|Sphingomonadales K Cro/C1-type HTH DNA-binding domain - - - - - - - - - - - - HTH_3,HTH_31 k59_204425_3 1321778.HMPREF1982_02686 9.84e-23 96.7 COG3728@1|root,COG3728@2|Bacteria,1VAD9@1239|Firmicutes,24JSU@186801|Clostridia 186801|Clostridia L Terminase Small Subunit - - - ko:K07474 - - - - ko00000 - - - Terminase_2 k59_204425_4 221360.RS9917_03953 3.39e-23 101.0 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria 2|Bacteria K chromosome segregation - - - - - - - - - - - - Terminase_6,Terminase_6C k59_211659_1 1144310.PMI07_002360 6.34e-08 61.2 2DPZ1@1|root,3340X@2|Bacteria,1R2EE@1224|Proteobacteria,2TZIB@28211|Alphaproteobacteria,4BP2Q@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_204426_1 369723.Strop_1948 1.45e-29 121.0 COG4676@1|root,COG4676@2|Bacteria,2GPA6@201174|Actinobacteria,4DCBY@85008|Micromonosporales 201174|Actinobacteria S Protein conserved in bacteria - - - - - - - - - - - - - k59_188020_1 999549.KI421514_gene431 9.68e-59 187.0 2EKAP@1|root,33E0Y@2|Bacteria,1NAAI@1224|Proteobacteria,2UI39@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_130498_1 1279019.ARQK01000045_gene517 4.52e-11 68.2 COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,1R97W@1224|Proteobacteria,1TK9M@1236|Gammaproteobacteria,1X0PG@135613|Chromatiales 135613|Chromatiales D Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_122032_1 1514668.JOOA01000001_gene228 4.22e-14 68.2 2C6KN@1|root,32Y69@2|Bacteria,1VANX@1239|Firmicutes,24MNG@186801|Clostridia,3WR17@541000|Ruminococcaceae 186801|Clostridia S VRR_NUC - - - - - - - - - - - - VRR_NUC k59_138436_1 1417296.U879_13410 2.9e-83 274.0 COG3378@1|root,COG3598@1|root,COG3378@2|Bacteria,COG3598@2|Bacteria,1MV7I@1224|Proteobacteria,2TRS2@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Phage plasmid primase P4 family - - - ko:K06919 - - - - ko00000 - - - D5_N k59_138436_2 1002672.SAR11G3_01288 1.75e-60 191.0 2AV7S@1|root,31KYE@2|Bacteria,1RKQ6@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_79782_1 1121943.KB900008_gene1991 1.37e-41 159.0 COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,1R97W@1224|Proteobacteria 1224|Proteobacteria D Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_179454_2 640513.Entas_3067 4.42e-18 82.0 2AC53@1|root,311PE@2|Bacteria,1REZC@1224|Proteobacteria,1RTXS@1236|Gammaproteobacteria,3X3V8@547|Enterobacter 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_13180_1 1636270.A0A0E3JSA3_9CAUD 5.17e-35 136.0 4QB5I@10239|Viruses,4QPQ9@28883|Caudovirales,4QNNS@10744|Podoviridae 10744|Podoviridae S SNF2 family N-terminal domain - - - - - - - - - - - - - k59_113858_1 1226994.AMZB01000137_gene5411 1.31e-20 89.0 2EIQ2@1|root,33CFI@2|Bacteria,1NHAI@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_113858_3 743720.Psefu_1426 1.71e-54 187.0 COG2404@1|root,COG2404@2|Bacteria,1MXEH@1224|Proteobacteria,1SADM@1236|Gammaproteobacteria 1236|Gammaproteobacteria S phosphoesterase DHHA1 - - - - - - - - - - - - DHHA1 k59_253369_2 1248916.ANFY01000007_gene2173 4.9e-06 48.9 2EDVK@1|root,337QQ@2|Bacteria,1N33T@1224|Proteobacteria,2UDD4@28211|Alphaproteobacteria,2K6R1@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - k59_253369_5 1260356.D920_01722 2.28e-65 236.0 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,4H9Z7@91061|Bacilli,4B0F6@81852|Enterococcaceae 91061|Bacilli L DNA polymerase family A polA_2 - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_30954_1 1500257.JQNM01000006_gene1748 5.99e-24 113.0 291GM@1|root,2ZP3A@2|Bacteria,1RD1E@1224|Proteobacteria,2UPJH@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_138620_1 1236000.L0AQQ6_9CAUD 7.02e-64 218.0 4QB9Y@10239|Viruses,4QWGZ@35237|dsDNA viruses no RNA stage,4QPTT@28883|Caudovirales,4QJD7@10662|Myoviridae 10662|Myoviridae S hydrolase activity - - - - - - - - - - - - - k59_253447_1 1385658.U5KPZ6_9VIRU 2.82e-86 270.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_253447_3 105154.Q9MBU0_9VIRU 4.91e-45 162.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_33025_2 10752.A0MZD8_BPN4 6.68e-23 94.7 4QAVS@10239|Viruses,4QX2I@35237|dsDNA viruses no RNA stage,4QR41@28883|Caudovirales,4QNSG@10744|Podoviridae 10744|Podoviridae S Protein of unknown function (DUF2829) - - - - - - - - - - - - - k59_190482_1 5786.XP_003291356.1 4.54e-21 97.4 COG5108@1|root,KOG1038@2759|Eukaryota,3XANZ@554915|Amoebozoa 554915|Amoebozoa K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates - - 2.7.7.6 ko:K10908 - - - - ko00000,ko01000,ko03029 - - - RNA_pol,RPOL_N k59_238379_1 665950.HMPREF1025_02007 1.86e-23 102.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_238379_2 742740.HMPREF9474_02263 1.14e-30 113.0 2ARVA@1|root,31H70@2|Bacteria,1V7JT@1239|Firmicutes,24JPE@186801|Clostridia,222RD@1506553|Lachnoclostridium 186801|Clostridia S Bacteriophage HK97-gp10, putative tail-component - - - - - - - - - - - - HK97-gp10_like k59_173906_2 4792.ETI31775 1.01e-60 211.0 2C7RP@1|root,2SPXE@2759|Eukaryota 2759|Eukaryota - - - - - - - - - - - - - - - k59_255221_1 240016.ABIZ01000001_gene5053 0.000404 49.7 2DR7Z@1|root,33AM6@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_206632_2 1150626.PHAMO_120006 7.87e-57 184.0 2E80D@1|root,332EP@2|Bacteria,1NAIR@1224|Proteobacteria 1224|Proteobacteria S Protein involved in DNA replication and plasmid maintenance - - - - - - - - - - - - RepL k59_197329_1 420324.KI911970_gene1463 1.38e-89 280.0 COG5410@1|root,COG5410@2|Bacteria,1N0W2@1224|Proteobacteria,2U18J@28211|Alphaproteobacteria 28211|Alphaproteobacteria K chromosome segregation - - - - - - - - - - - - Terminase_6C k59_132163_1 1385658.U5KPZ6_9VIRU 6.5e-87 275.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_132164_2 1788444.A0A190WHB9_9CIRC 1.79e-26 106.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_264552_4 490913.C4NTC6_9CAUD 2.08e-66 207.0 4QAZ8@10239|Viruses,4R074@35237|dsDNA viruses no RNA stage,4QQTR@28883|Caudovirales,4QNX4@10744|Podoviridae 10744|Podoviridae S DNA mediated transformation - - - - - - - - - - - - - k59_264552_5 1120958.AULD01000012_gene1416 1.02e-24 98.2 COG1595@1|root,COG1595@2|Bacteria,2ISW5@201174|Actinobacteria,4FPVS@85023|Microbacteriaceae 201174|Actinobacteria K DNA-templated transcription, initiation - - - - - - - - - - - - - k59_264552_8 1238182.C882_1645 1.12e-31 119.0 COG4186@1|root,COG4186@2|Bacteria,1RD94@1224|Proteobacteria,2U7MY@28211|Alphaproteobacteria,2JSF5@204441|Rhodospirillales 204441|Rhodospirillales S Phosphoesterase or phosphohydrolase - - - - - - - - - - - - Metallophos_2 k59_264552_9 1477404.A0A023NGD2_9CAUD 6.23e-48 156.0 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales,4QNBQ@10744|Podoviridae 10744|Podoviridae S HNH endonuclease - - - - - - - - - - - - - k59_264552_12 1477404.A0A023NFZ3_9CAUD 1.25e-145 434.0 4QE52@10239|Viruses,4QZPT@35237|dsDNA viruses no RNA stage,4QU1C@28883|Caudovirales,4QNTJ@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_24758_1 742740.HMPREF9474_02314 8.22e-37 134.0 2A0KC@1|root,30NQJ@2|Bacteria,1V3K4@1239|Firmicutes,24HYK@186801|Clostridia,222N6@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_82886_1 1692257.A0A0K1RL39_9CIRC 3.55e-50 172.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_82886_2 1692242.A0A0K1RKZ2_9CIRC 2.87e-23 101.0 4QFEW@10239|Viruses,4QUKZ@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_41143_1 359.CN09_06780 5.07e-10 70.1 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2TQZE@28211|Alphaproteobacteria,4B7XC@82115|Rhizobiaceae 28211|Alphaproteobacteria M Membrane proteins related to metalloendopeptidases MA20_30780 - - - - - - - - - - - Peptidase_M23 k59_89441_1 1116472.MGMO_205c00050 4.81e-43 146.0 28HVF@1|root,2Z81Q@2|Bacteria,1NZPF@1224|Proteobacteria,1SRZ6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Bacteriophage scaffolding protein D - - - - - - - - - - - - gpD k59_41148_1 926550.CLDAP_25590 2.18e-51 183.0 COG1572@1|root,COG1572@2|Bacteria 2|Bacteria NU bacterial-type flagellum-dependent cell motility - - - - - - - - - - - - BatA,CARDB,DUF3367,DUF4091,DUF4159 k59_214993_5 1246626.BleG1_3033 1.13e-19 94.0 COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,4HB9Q@91061|Bacilli,1ZBKA@1386|Bacillus 91061|Bacilli D peptidase - - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M23 k59_265011_2 1379725.S5TMY9_9CIRC 6.72e-36 139.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_98881_1 1197951.I6R9K8_9CAUD 1.41e-88 272.0 4QFIC@10239|Viruses,4QXG2@35237|dsDNA viruses no RNA stage,4QTVA@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_41358_1 1439940.BAY1663_02360 1.24e-14 79.0 28JTG@1|root,2Z9IR@2|Bacteria,1PCXZ@1224|Proteobacteria,1SIJB@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF2793) - - - - - - - - - - - - DUF2793 k59_256871_1 1288079.AUKN01000018_gene2497 4.23e-40 159.0 28NJJ@1|root,2ZBKQ@2|Bacteria,2IBUV@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - Prim-Pol k59_265044_2 1618254.A0A0C5IBG4_9CIRC 4.55e-131 380.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_215195_1 1788447.A0A190WHJ9_9CIRC 3.13e-99 299.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_89630_1 1128421.JAGA01000002_gene516 5.01e-28 112.0 COG1351@1|root,COG1351@2|Bacteria,2NPQ2@2323|unclassified Bacteria 2|Bacteria F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant thyX - 2.1.1.148 ko:K03465 ko00240,ko00670,ko01100,map00240,map00670,map01100 - R06613 RC00022,RC00332 ko00000,ko00001,ko01000 - - - HNH,Thy1 k59_89630_2 1327982.R9ZYM1_9CAUD 3.07e-51 170.0 4QD0J@10239|Viruses,4R0A5@35237|dsDNA viruses no RNA stage,4QSK9@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_240030_1 402626.Rpic_2546 0.000182 52.0 2EE5J@1|root,33803@2|Bacteria,1NB1A@1224|Proteobacteria,2VVPM@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_107443_2 77856.REP_BFDV 6.63e-21 92.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_215204_1 1475063.W8SWD2_9CIRC 3.98e-15 81.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_41366_1 1449343.JQLQ01000002_gene1551 9.3e-10 60.1 COG1196@1|root,COG1196@2|Bacteria,1TQY7@1239|Firmicutes,4HCRF@91061|Bacilli 91061|Bacilli D Psort location Cytoplasmic, score - - - - - - - - - - - - AAA_23,AAA_27 k59_108112_6 1234888.K0A2J2_9VIRU 1.21e-109 337.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_149450_1 428125.CLOLEP_01379 3.01e-18 85.5 COG0553@1|root,COG0553@2|Bacteria,1TS9W@1239|Firmicutes,24CGX@186801|Clostridia,3WN6X@541000|Ruminococcaceae 186801|Clostridia KL Helicase conserved C-terminal domain - - - - - - - - - - - - - k59_33493_2 1732201.A0A0N9N7I3_9CIRC 2.31e-17 89.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_174231_2 76869.PputGB1_1746 5.73e-123 376.0 COG0507@1|root,COG0507@2|Bacteria,1R1AT@1224|Proteobacteria,1RS66@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Participates in initiation and elongation during chromosome replication - - - - - - - - - - - - - k59_174231_5 76869.PputGB1_1748 6.29e-74 253.0 28HPK@1|root,2Z7XJ@2|Bacteria,1NBHR@1224|Proteobacteria,1RZ7H@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_174231_8 194699.Q775C7_BPBPP 3.16e-108 325.0 4QH0X@10239|Viruses,4QXIJ@35237|dsDNA viruses no RNA stage,4QSY6@28883|Caudovirales,4QNTU@10744|Podoviridae 10744|Podoviridae S viral capsid - - - - - - - - - - - - - k59_174231_12 492774.JQMB01000013_gene3024 4.84e-22 110.0 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,2TVGJ@28211|Alphaproteobacteria,4BH6J@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_174231_16 520999.PROVALCAL_01874 0.000127 56.2 28HCK@1|root,2Z7PE@2|Bacteria,1NK7S@1224|Proteobacteria,1S03Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_174231_17 652103.Rpdx1_2535 1.02e-06 60.5 2DQ9V@1|root,335IH@2|Bacteria 2|Bacteria - - - - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - - k59_174231_35 1410620.SHLA_4c002110 5.04e-39 140.0 COG0237@1|root,COG0237@2|Bacteria,1NEFS@1224|Proteobacteria,2UIWS@28211|Alphaproteobacteria,4BKKU@82115|Rhizobiaceae 28211|Alphaproteobacteria H dephospho-CoA kinase activity - - - - - - - - - - - - - k59_174231_36 906968.Trebr_1735 1.46e-14 78.2 COG1475@1|root,COG1475@2|Bacteria,2J7KN@203691|Spirochaetes 203691|Spirochaetes K ParB-like nuclease domain - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_41757_1 1385658.U5KNR1_9VIRU 5.84e-48 168.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_41757_3 1385658.U5KPZ6_9VIRU 9.27e-175 510.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_41757_4 105154.Q9MBU3_9VIRU 1.22e-14 77.8 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_116426_1 1112209.AHVZ01000042_gene974 1.34e-152 432.0 COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,1RP6Z@1236|Gammaproteobacteria,3NK5G@468|Moraxellaceae 1236|Gammaproteobacteria E Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family ilvE GO:0003674,GO:0003824,GO:0004084,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006531,GO:0006532,GO:0006551,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009098,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - iB21_1397.B21_03597,iECBD_1354.ECBD_4269,iECB_1328.ECB_03648,iECD_1391.ECD_03648,iECO103_1326.ECO103_4394 Aminotran_4 k59_149456_1 1385658.U5KPZ6_9VIRU 1.02e-63 213.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_66646_1 1235755.ANAM01000006_gene2384 1.95e-05 50.8 COG0739@1|root,COG1193@1|root,COG5280@1|root,COG5283@1|root,COG0739@2|Bacteria,COG1193@2|Bacteria,COG5280@2|Bacteria,COG5283@2|Bacteria,1UHQM@1239|Firmicutes,4HGW7@91061|Bacilli,4H1TE@90964|Staphylococcaceae 91061|Bacilli M tail protein - - - - - - - - - - - - Peptidase_M23,PhageMin_Tail,Sipho_tail k59_75624_3 742821.HMPREF9464_01832 6.25e-35 130.0 COG3740@1|root,COG3740@2|Bacteria,1N2D8@1224|Proteobacteria,2VX9U@28216|Betaproteobacteria 28216|Betaproteobacteria S Caudovirus prohead serine protease - - - ko:K06904 - - - - ko00000 - - - Peptidase_S78 k59_216711_1 1094561.MEI_00509 2.86e-21 98.6 2CC8M@1|root,308VJ@2|Bacteria,1R789@1224|Proteobacteria,2U2NB@28211|Alphaproteobacteria,48TVI@772|Bartonellaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_83758_2 979525.F1D1L3_9CAUD 3.92e-08 61.6 4QARC@10239|Viruses,4QV4E@35237|dsDNA viruses no RNA stage,4QPDS@28883|Caudovirales,4QIV1@10662|Myoviridae 10662|Myoviridae S nucleic acid binding - - - - - - - - - - - - - k59_50722_1 997296.PB1_13449 3.51e-77 239.0 COG0207@1|root,COG0207@2|Bacteria,1TSIR@1239|Firmicutes,4H9QS@91061|Bacilli,1ZAUT@1386|Bacillus 91061|Bacilli F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046385,GO:0046483,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt k59_150293_3 10756.PORTL_BPPH2 1.98e-09 60.5 4QDW3@10239|Viruses 10239|Viruses S Phage Connector (GP10) - GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019028,GO:0019058,GO:0019068,GO:0019072,GO:0019073,GO:0032991,GO:0044403,GO:0044419,GO:0044423,GO:0046729,GO:0046798,GO:0051704 - - - - - - - - - - - k59_9222_1 1219035.NT2_13_00580 4.13e-33 130.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_249715_2 1618248.A0A0C5IB82_9CIRC 4.53e-22 98.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_117099_3 1217715.F994_02116 4.97e-22 87.8 COG1551@1|root,COG1551@2|Bacteria,1N6PG@1224|Proteobacteria,1SCB4@1236|Gammaproteobacteria,3NNX1@468|Moraxellaceae 1236|Gammaproteobacteria T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding csrA GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005979,GO:0006109,GO:0006139,GO:0006417,GO:0006446,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0010675,GO:0010677,GO:0010906,GO:0010962,GO:0016070,GO:0016071,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032881,GO:0032885,GO:0034248,GO:0034249,GO:0034641,GO:0043170,GO:0043255,GO:0043467,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045719,GO:0045912,GO:0045947,GO:0046483,GO:0048027,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0062012,GO:0065007,GO:0070873,GO:0070874,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:2000112,GO:2000113 - ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 - - - ko00000,ko00001,ko03019 - - - CsrA k59_117099_4 359.CN09_13050 6.94e-14 79.7 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2TRJF@28211|Alphaproteobacteria,4B86G@82115|Rhizobiaceae 28211|Alphaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_150347_1 1100720.ALKN01000018_gene1739 3.22e-83 263.0 28J3M@1|root,2Z8ZT@2|Bacteria,1Q2A4@1224|Proteobacteria,2VNFP@28216|Betaproteobacteria,4A9TU@80864|Comamonadaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_150347_2 1175654.A0A0S0NAE1_9CAUD 7.07e-11 67.0 4QB0T@10239|Viruses,4QV4X@35237|dsDNA viruses no RNA stage,4QPUT@28883|Caudovirales,4QKQK@10699|Siphoviridae 10699|Siphoviridae S Protein of unknown function (DUF669) - - - - - - - - - - - - - k59_150347_4 641112.ACOK01000073_gene2874 0.000388 44.3 28HHC@1|root,2Z7T2@2|Bacteria,1TR3B@1239|Firmicutes,24D5P@186801|Clostridia 186801|Clostridia S AAA domain - - - - - - - - - - - - AAA_24 k59_183419_2 1574422.A0A0A1ENW9_9CIRC 2.96e-37 141.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_183420_1 547042.BACCOPRO_01614 1.15e-19 91.3 2A7Y4@1|root,30WY0@2|Bacteria,4PAAD@976|Bacteroidetes,2FWFE@200643|Bacteroidia,4ATHJ@815|Bacteroidaceae 976|Bacteroidetes - - - - - - - - - - - - - - - k59_17346_2 1788442.A0A190WH98_9CIRC 5.32e-24 104.0 4QB6C@10239|Viruses,4QUKM@29258|ssDNA viruses 10239|Viruses J Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_167886_1 1379717.S5SY19_9CIRC 5.8e-50 167.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_167886_4 1379718.S5TMX4_9CIRC 6.96e-33 125.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_51748_1 335284.Pcryo_2399 1.61e-111 348.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,3NJS6@468|Moraxellaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k59_84585_1 1517681.HW45_25210 8.2e-15 77.8 COG2946@1|root,COG2946@2|Bacteria,1PMVG@1224|Proteobacteria,1THIG@1236|Gammaproteobacteria,1XW3N@135623|Vibrionales 135623|Vibrionales L Replication initiation factor - - - ko:K07467 - - - - ko00000 - - - Rep_trans k59_134725_1 1692253.A0A0K1RLM4_9CIRC 1.19e-16 85.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_118343_1 1212548.B381_12266 9.93e-35 132.0 COG3213@1|root,COG3213@2|Bacteria,1RE7Q@1224|Proteobacteria,1S3UC@1236|Gammaproteobacteria,1Z1KZ@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria P protein involved in response to NO - - - - - - - - - - - - NnrS k59_184170_1 1609634.A0A0C5AFV4_9VIRU 7.89e-13 67.8 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_184170_2 105154.Q9MBU3_9VIRU 1.88e-09 63.2 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_184170_4 1385658.U5KNR1_9VIRU 1.13e-64 213.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_184170_6 1385658.U5KPZ6_9VIRU 1.64e-176 514.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_59712_1 1986029.Q9MBM8_9VIRU 5.29e-186 540.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_242228_2 105154.Q9MBU3_9VIRU 9.77e-12 68.6 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_242228_3 1986029.Q9MBM8_9VIRU 4.97e-07 50.1 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_192240_2 105154.Q9MBU0_9VIRU 1.12e-46 167.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_159884_1 51369.Q9T0Y1_9CAUD 3.91e-06 50.8 4QAY9@10239|Viruses,4QV7W@35237|dsDNA viruses no RNA stage,4QPAN@28883|Caudovirales,4QKV1@10699|Siphoviridae 10699|Siphoviridae S hydrolase activity - - - - - - - - - - - - - k59_44110_1 935261.JAGL01000009_gene1165 3.68e-70 231.0 COG0209@1|root,COG0209@2|Bacteria,1PM78@1224|Proteobacteria,2UZUM@28211|Alphaproteobacteria,43QGW@69277|Phyllobacteriaceae 28211|Alphaproteobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides - - - - - - - - - - - - - k59_93577_3 765913.ThidrDRAFT_4325 2.74e-05 55.1 COG0438@1|root,COG0438@2|Bacteria,1N5HW@1224|Proteobacteria,1RPPH@1236|Gammaproteobacteria,1WY5F@135613|Chromatiales 135613|Chromatiales M PFAM Glycosyl transferase, group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k59_135495_1 145579.B_BPPHM 2.87e-17 80.1 4QDBB@10239|Viruses,4QUM0@29258|ssDNA viruses,4QP4D@10841|Microviridae 10841|Microviridae S Chlamydia-phage Chp2 scaffold (Chlamy_scaf) - - - - - - - - - - - - - k59_144012_1 926554.KI912617_gene4764 4.64e-21 95.9 2C9JF@1|root,32RPD@2|Bacteria 2|Bacteria S Erf family - - - - - - - - - - - - ERF k59_18812_1 1144313.PMI10_00662 7.21e-35 139.0 2C0EQ@1|root,3492A@2|Bacteria,4P5TY@976|Bacteroidetes,1IAIT@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_192921_1 145579.CAPSD_BPPHM 3.74e-56 193.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_135583_1 1200557.JHWV01000001_gene289 5.19e-05 53.5 COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,4H206@909932|Negativicutes 909932|Negativicutes L Participates in initiation and elongation during chromosome replication - - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_135583_3 504472.Slin_0543 2.37e-33 144.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,47KYI@768503|Cytophagia 976|Bacteroidetes L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_10639_2 926549.KI421517_gene2362 3.82e-49 165.0 2C0VP@1|root,32ZQ9@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_152312_1 221538.REP_TYCS2 1.57e-09 60.8 4QB6C@10239|Viruses,4QUKM@29258|ssDNA viruses 10239|Viruses J Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_176721_2 904144.AEJD01000006_gene541 2.92e-22 103.0 COG2887@1|root,COG2887@2|Bacteria,2IBBB@201174|Actinobacteria 201174|Actinobacteria L Protein of unknown function (DUF2800) - - - - - - - - - - - - DUF2800 k59_60420_1 352165.HMPREF7215_2591 1.73e-35 138.0 COG5410@1|root,COG5410@2|Bacteria 2|Bacteria K chromosome segregation - - - - - - - - - - - - Terminase_6,Terminase_6C k59_93667_1 742740.HMPREF9474_02314 1e-51 173.0 2A0KC@1|root,30NQJ@2|Bacteria,1V3K4@1239|Firmicutes,24HYK@186801|Clostridia,222N6@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_201716_1 438753.AZC_3598 2.22e-36 137.0 COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1QT52@1224|Proteobacteria,2TVNI@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Toprim-like - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - DnaB_C,Toprim_2 k59_226671_1 1123072.AUDH01000038_gene151 2.36e-30 126.0 COG5281@1|root,COG5281@2|Bacteria,1MX2R@1224|Proteobacteria,2U3WK@28211|Alphaproteobacteria,2JTUX@204441|Rhodospirillales 204441|Rhodospirillales D tape measure protein - - - - - - - - - - - - - k59_227708_5 1117318.PRUB_08799 5.13e-28 107.0 COG3772@1|root,COG3772@2|Bacteria,1N0ZQ@1224|Proteobacteria,1S9AE@1236|Gammaproteobacteria,2Q38I@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S Phage lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_128678_1 1504672.669782883 2.76e-19 94.0 COG1040@1|root,COG1674@1|root,COG3087@1|root,COG1040@2|Bacteria,COG1674@2|Bacteria,COG3087@2|Bacteria,1QV41@1224|Proteobacteria,2VMZ1@28216|Betaproteobacteria 28216|Betaproteobacteria D ftsk spoiiie - - - - - - - - - - - - - k59_210424_2 953739.SVEN_0580 3.68e-65 204.0 COG1428@1|root,COG1428@2|Bacteria,2H6BK@201174|Actinobacteria 201174|Actinobacteria F Deoxynucleoside kinase - - - - - - - - - - - - dNK k59_220319_1 616991.JPOO01000003_gene1560 1.36e-19 87.0 COG2227@1|root,COG2227@2|Bacteria,4NM91@976|Bacteroidetes,1HZAR@117743|Flavobacteriia,23GJE@178469|Arenibacter 976|Bacteroidetes H 3-demethylubiquinone-9 3-O-methyltransferase activity - - - - - - - - - - - - - k59_103032_3 105154.Q9MBU6_9VIRU 2.13e-188 546.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_251907_1 7213.XP_004518328.1 7.07e-23 99.8 2CMNT@1|root,2QR3D@2759|Eukaryota,39UHX@33154|Opisthokonta,3B9U3@33208|Metazoa,3D2YM@33213|Bilateria,4201I@6656|Arthropoda,3SMSN@50557|Insecta,44Z6J@7147|Diptera 33208|Metazoa G N-acetylmuramoyl-L-alanine amidase activity. It is involved in the biological process described with peptidoglycan catabolic process PGRPLB - - ko:K01446 - - R04112 RC00064,RC00141 ko00000 - - - Amidase_2 k59_251907_4 1229780.BN381_100142 4.86e-33 120.0 COG0629@1|root,COG0629@2|Bacteria,2GMM3@201174|Actinobacteria,3UWQD@52018|unclassified Actinobacteria (class) 201174|Actinobacteria L Single-strand binding protein family ssb GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0033554,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071944,GO:0097159,GO:1901363 - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_251907_6 1120983.KB894577_gene3655 6.5e-68 229.0 COG5323@1|root,COG5323@2|Bacteria,1MW8S@1224|Proteobacteria,2TREI@28211|Alphaproteobacteria,1JNNI@119043|Rhodobiaceae 28211|Alphaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_61131_1 1238450.VIBNISOn1_550017 6.98e-28 106.0 COG2852@1|root,COG2852@2|Bacteria,1N2UX@1224|Proteobacteria,1TIHC@1236|Gammaproteobacteria,1XZ4M@135623|Vibrionales 135623|Vibrionales S Protein conserved in bacteria - - - - - - - - - - - - - k59_128690_1 1027273.GZ77_17025 1.14e-10 67.4 COG1061@1|root,COG1061@2|Bacteria,1MV9F@1224|Proteobacteria,1RNAN@1236|Gammaproteobacteria,1XH5K@135619|Oceanospirillales 135619|Oceanospirillales L helicase superfamily c-terminal domain - - - ko:K19789 - - - - ko00000,ko03400 - - - Helicase_C,ResIII k59_111824_2 1205680.CAKO01000001_gene3133 9.86e-44 154.0 COG3409@1|root,COG3409@2|Bacteria,1NAI5@1224|Proteobacteria 1224|Proteobacteria M N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - Amidase_2,PG_binding_1 k59_136625_3 1300005.R9RG81_9CAUD 0.000245 48.1 4QH0W@10239|Viruses,4QXII@35237|dsDNA viruses no RNA stage,4QSY7@28883|Caudovirales 28883|Caudovirales S virus tail - GO:0005575,GO:0019012,GO:0044423,GO:0098015 - - - - - - - - - - - k59_202873_1 77856.REP_BFDV 2.83e-17 84.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_227796_1 673376.F2VHW3_9CAUD 2.91e-37 135.0 4QBHW@10239|Viruses,4QW8N@35237|dsDNA viruses no RNA stage,4QTT7@28883|Caudovirales,4QKR7@10699|Siphoviridae 10699|Siphoviridae S sequence-specific DNA binding transcription factor activity - - - - - - - - - - - - - k59_193955_3 690850.Desaf_0681 9.65e-17 78.2 2AD08@1|root,312N7@2|Bacteria,1NDC4@1224|Proteobacteria,42VQI@68525|delta/epsilon subdivisions,2WS8T@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Holin of 3TMs, for gene-transfer release - - - - - - - - - - - - GTA_holin_3TM k59_194730_1 279238.Saro_2987 7.28e-75 239.0 2CYA9@1|root,32T3V@2|Bacteria,1RGRN@1224|Proteobacteria,2U90D@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_46485_1 926564.KI911577_gene452 3.97e-86 273.0 COG0749@1|root,COG0749@2|Bacteria,2I975@201174|Actinobacteria 201174|Actinobacteria L COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains - - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - DNA_pol_A,DNA_pol_A_exo1 k59_46485_4 1003195.SCAT_1653 2.86e-20 85.1 2EI4V@1|root,33BW7@2|Bacteria,2I5MI@201174|Actinobacteria 201174|Actinobacteria S Protein of unknwon function (DUF3310) - - - - - - - - - - - - DUF3310 k59_46485_5 1556290.A0A0A0RM00_9CAUD 4.1e-40 149.0 4QAXQ@10239|Viruses,4QRFY@28883|Caudovirales,4QM52@10699|Siphoviridae 10699|Siphoviridae S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor - - - - - - - - - - - - - k59_103873_1 102129.Lepto7375DRAFT_4567 4.93e-68 230.0 COG1511@1|root,COG1511@2|Bacteria,1G70J@1117|Cyanobacteria,1HCMJ@1150|Oscillatoriales 1117|Cyanobacteria S domain protein - - - - - - - - - - - - Collagen k59_228699_1 105154.Q9MBU6_9VIRU 6.13e-124 374.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_62038_1 490913.C4NTB3_9CAUD 3.15e-21 85.5 4QH70@10239|Viruses,4QYSD@35237|dsDNA viruses no RNA stage,4QTP3@28883|Caudovirales,4QNI1@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_62038_2 1335230.S5VZM6_9CAUD 7.7e-23 89.7 4QAVS@10239|Viruses,4QX2I@35237|dsDNA viruses no RNA stage,4QR41@28883|Caudovirales,4QIEF@10662|Myoviridae 10662|Myoviridae S Protein of unknown function (DUF2829) - - - - - - - - - - - - - k59_129744_1 1618238.A0A0C5I2G8_9CIRC 6.91e-24 103.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_121191_1 1415775.U729_3209 1.92e-14 74.3 2DR9Y@1|root,33AUY@2|Bacteria,1VEP1@1239|Firmicutes,24VBK@186801|Clostridia 186801|Clostridia L HNH endonuclease - - - - - - - - - - - - HNH_3,NUMOD4 k59_5431_1 326442.PSHAa1556 2.01e-16 94.4 COG4733@1|root,COG4733@2|Bacteria,1R7KR@1224|Proteobacteria,1S1E5@1236|Gammaproteobacteria,2Q40F@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S Fibronectin type 3 domain - - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - DUF1983,Phage-tail_3 k59_194832_1 1158150.KB906242_gene227 3.53e-58 201.0 28IA2@1|root,2Z8CQ@2|Bacteria,1PQM2@1224|Proteobacteria,1SN3W@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_29990_1 742767.HMPREF9456_03368 3.22e-45 175.0 COG5280@1|root,COG5280@2|Bacteria,4PNYN@976|Bacteroidetes,2FPMT@200643|Bacteroidia 976|Bacteroidetes S domain protein - - - - - - - - - - - - - k59_95351_2 318464.IO99_00465 5.76e-07 58.9 2DI7K@1|root,3029C@2|Bacteria,1UPX0@1239|Firmicutes,25HR0@186801|Clostridia,36VC3@31979|Clostridiaceae 186801|Clostridia S Protein of unknown function (DUF1351) - - - - - - - - - - - - DUF1351 k59_95351_5 1453501.JELR01000005_gene1754 1.88e-65 206.0 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria,466WC@72275|Alteromonadaceae 1236|Gammaproteobacteria L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_95351_6 997353.HMPREF9144_0262 5.74e-49 166.0 COG0863@1|root,COG0863@2|Bacteria,4NQQ1@976|Bacteroidetes 976|Bacteroidetes L DNA methylase - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_54733_1 5875.XP_764139.1 2.96e-24 102.0 COG0207@1|root,COG0262@1|root,KOG0673@2759|Eukaryota,KOG1324@2759|Eukaryota,3Y9V0@5794|Apicomplexa,3KA8B@422676|Aconoidasida,3Z4T4@5863|Piroplasmida 422676|Aconoidasida H Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism - GO:0000082,GO:0000083,GO:0000278,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004799,GO:0005488,GO:0005542,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0005829,GO:0006082,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006259,GO:0006355,GO:0006417,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006753,GO:0006760,GO:0006793,GO:0006796,GO:0006807,GO:0007049,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009157,GO:0009162,GO:0009165,GO:0009176,GO:0009177,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015949,GO:0016020,GO:0016740,GO:0016741,GO:0017148,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019692,GO:0019752,GO:0019842,GO:0019866,GO:0022402,GO:0030371,GO:0031090,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032259,GO:0032268,GO:0032269,GO:0033218,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0034654,GO:0035999,GO:0036094,GO:0042083,GO:0042221,GO:0042558,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044770,GO:0044772,GO:0044843,GO:0045182,GO:0046073,GO:0046385,GO:0046483,GO:0046653,GO:0046683,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051186,GO:0051246,GO:0051248,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0070013,GO:0071704,GO:0071897,GO:0072341,GO:0072527,GO:0072528,GO:0080090,GO:0090079,GO:0090304,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903047,GO:1903506,GO:1990825,GO:2000112,GO:2000113,GO:2001141 1.5.1.3,2.1.1.45 ko:K13998 ko00240,ko00670,ko00790,ko01100,map00240,map00670,map00790,map01100 M00053,M00126,M00841 R00936,R00937,R00939,R00940,R02101,R02235,R02236 RC00109,RC00110,RC00158,RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - DHFR_1,Thymidylat_synt k59_261913_2 1123239.KB898628_gene3227 2.84e-14 75.9 2DR9Y@1|root,33AUY@2|Bacteria,1VEP1@1239|Firmicutes,4HP3X@91061|Bacilli 91061|Bacilli L NUMOD4 motif - - - - - - - - - - - - HNH_3,NUMOD4 k59_171037_1 440250.A5HL39_9CAUD 2.88e-24 119.0 4QBWF@10239|Viruses,4QZPF@35237|dsDNA viruses no RNA stage,4QRA3@28883|Caudovirales,4QNG4@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_221499_2 1476391.X5KIN0_9CAUD 1.29e-85 268.0 4QEG2@10239|Viruses,4QVSD@35237|dsDNA viruses no RNA stage,4QRJ9@28883|Caudovirales,4QP0R@10744|Podoviridae 10744|Podoviridae S exonuclease activity - - - - - - - - - - - - - k59_161918_1 1385935.N836_31600 2.49e-32 122.0 29WCJ@1|root,30HY6@2|Bacteria,1GGB6@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - k59_38233_1 272942.RCAP_rcc01080 1.48e-27 112.0 2CZBU@1|root,32T60@2|Bacteria,1N7TC@1224|Proteobacteria,2UIQ6@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_155393_6 1042375.AFPL01000032_gene858 3.93e-85 254.0 COG0741@1|root,COG0741@2|Bacteria,1N1XZ@1224|Proteobacteria,1SACS@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Transglycosylase SLT domain - - - - - - - - - - - - SLT k59_155393_7 1244869.H261_11879 2.8e-08 55.8 COG0741@1|root,COG0741@2|Bacteria,1N1XZ@1224|Proteobacteria,2UB2Y@28211|Alphaproteobacteria,2JWX1@204441|Rhodospirillales 204441|Rhodospirillales M Transglycosylase SLT domain - - - - - - - - - - - - SLT k59_147720_1 298653.Franean1_5114 3.12e-33 129.0 COG0675@1|root,COG0675@2|Bacteria,2GM6K@201174|Actinobacteria,4EVHQ@85013|Frankiales 201174|Actinobacteria L Transposase, IS605 OrfB family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K07496 - - - - ko00000 - - - HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon k59_172078_1 1385658.U5KNR1_9VIRU 9.54e-17 84.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_122370_1 1692249.A0A0K1RLN8_9CIRC 5.95e-14 71.6 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_114200_2 1385658.U5KPZ6_9VIRU 2.11e-153 451.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_96155_1 1444310.JANV01000096_gene3227 2.19e-06 54.3 2EN4Y@1|root,32KKF@2|Bacteria,1UBN5@1239|Firmicutes,4IN2Q@91061|Bacilli,1ZMP2@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k59_172083_1 66875.JODY01000012_gene1450 1.39e-06 55.5 COG0673@1|root,COG0673@2|Bacteria,2GN2Z@201174|Actinobacteria 201174|Actinobacteria S oxidoreductase ydgJ - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C k59_253616_1 1122197.ATWI01000011_gene460 4.91e-51 174.0 COG0433@1|root,COG0433@2|Bacteria,1QTVP@1224|Proteobacteria,1T1IQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Zonular occludens toxin (Zot) - - - ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko02042 - - - Zot k59_130872_2 36080.S2JJ24 9.47e-10 70.5 COG0553@1|root,KOG0386@2759|Eukaryota,38FDR@33154|Opisthokonta,3NX7W@4751|Fungi,1GW7T@112252|Fungi incertae sedis 4751|Fungi A Snf2-ATP coupling, chromatin remodelling complex snf21 GO:0000003,GO:0000086,GO:0000122,GO:0000166,GO:0000228,GO:0000278,GO:0000785,GO:0000790,GO:0000988,GO:0000990,GO:0000991,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006302,GO:0006323,GO:0006325,GO:0006333,GO:0006337,GO:0006338,GO:0006342,GO:0006351,GO:0006354,GO:0006355,GO:0006357,GO:0006366,GO:0006368,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007010,GO:0007049,GO:0007059,GO:0008026,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0010959,GO:0015616,GO:0016043,GO:0016070,GO:0016458,GO:0016462,GO:0016514,GO:0016584,GO:0016586,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022402,GO:0022411,GO:0022414,GO:0022607,GO:0030554,GO:0031055,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031497,GO:0031498,GO:0031974,GO:0031981,GO:0032392,GO:0032508,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032879,GO:0032984,GO:0032986,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0034728,GO:0034756,GO:0035639,GO:0036094,GO:0040029,GO:0042393,GO:0042623,GO:0043044,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043269,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0044770,GO:0044772,GO:0044839,GO:0045814,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051276,GO:0051321,GO:0051716,GO:0060255,GO:0061587,GO:0065007,GO:0070013,GO:0070035,GO:0070577,GO:0070603,GO:0071103,GO:0071704,GO:0071824,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140030,GO:0140033,GO:0140097,GO:0140110,GO:1900390,GO:1900393,GO:1900400,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1902679,GO:1903047,GO:1903506,GO:1903507,GO:1904949,GO:2000112,GO:2000113,GO:2001141 - ko:K11786 - - - - ko00000,ko01000,ko03021,ko03036 - - - Bromodomain,HSA,Helicase_C,QLQ,SNF2_N,SnAC k59_38374_2 1618254.A0A0C5IBG4_9CIRC 3.05e-38 135.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_21498_1 313596.RB2501_01301 3.99e-50 176.0 2C0EQ@1|root,3492A@2|Bacteria,4P5TY@976|Bacteroidetes,1IAIT@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_115200_2 460265.Mnod_2507 3.96e-29 115.0 COG3723@1|root,COG3723@2|Bacteria,1R6DB@1224|Proteobacteria,2U82T@28211|Alphaproteobacteria,1JXG9@119045|Methylobacteriaceae 28211|Alphaproteobacteria L PFAM RecT protein - - - ko:K07455 - - - - ko00000,ko03400 - - - RecT k59_223602_1 1609634.A0A0C5ANA6_9VIRU 9.54e-12 64.3 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_223602_2 1609634.A0A0C5AFV4_9VIRU 9.72e-82 258.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_56576_2 517433.PanABDRAFT_2903 7.82e-17 78.6 2DWCB@1|root,33ZKQ@2|Bacteria,1N9DB@1224|Proteobacteria,1SEMC@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_56576_3 985762.SAGN_11252 2.16e-17 74.3 COG1724@1|root,COG1724@2|Bacteria,1U4QC@1239|Firmicutes,4IEN0@91061|Bacilli,4H105@90964|Staphylococcaceae 91061|Bacilli N HicA toxin of bacterial toxin-antitoxin, - - - - - - - - - - - - HicA_toxin k59_230471_1 1297863.APJF01000020_gene2704 4.24e-14 79.7 28JTG@1|root,2Z9IR@2|Bacteria,1R0GC@1224|Proteobacteria,2TURR@28211|Alphaproteobacteria,3JUCC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF2793) - - - - - - - - - - - - DUF2793 k59_163695_1 1676988.A0A0H4FNQ1_9CIRC 4.47e-14 76.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_180687_1 1340493.JNIF01000003_gene2420 1.97e-10 73.6 2DP40@1|root,330F7@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_22352_2 1292034.OR37_00713 3.48e-09 60.1 2EPBG@1|root,33GY8@2|Bacteria,1NQ0N@1224|Proteobacteria,2UM1M@28211|Alphaproteobacteria,2KHUU@204458|Caulobacterales 204458|Caulobacterales S Protein of unknown function (DUF1353) - - - - - - - - - - - - DUF1353 k59_237645_1 691965.D4P7I3_9CAUD 1.09e-135 424.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_139908_3 1100720.ALKN01000067_gene2326 1.03e-81 257.0 COG5655@1|root,COG5655@2|Bacteria,1N22J@1224|Proteobacteria 1224|Proteobacteria L Replication protein - - - - - - - - - - - - Rep_1 k59_39176_1 1618241.A0A0C5I2I4_9CIRC 1.36e-39 145.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_246191_1 485918.Cpin_4755 4.35e-05 51.6 COG3420@1|root,COG3420@2|Bacteria,4P11U@976|Bacteroidetes 976|Bacteroidetes P Periplasmic copper-binding protein (NosD) - - - - - - - - - - - - Beta_helix k59_22428_1 1122604.JONR01000046_gene2090 3.97e-24 105.0 28P6A@1|root,2ZC10@2|Bacteria,1RBZE@1224|Proteobacteria,1RRNS@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_73143_2 4538.ORGLA07G0186100.1 1.09e-06 58.5 COG0553@1|root,KOG1001@2759|Eukaryota,37IVF@33090|Viridiplantae,3G7HD@35493|Streptophyta,3KPFY@4447|Liliopsida,3I8NY@38820|Poales 35493|Streptophyta KL Prokaryotic RING finger family 4 - - 2.3.2.27 ko:K15711 - - - - ko00000,ko01000,ko03400,ko04121 - - - HIRAN,Helicase_C,SNF2_N,zf-C3HC4,zf-C3HC4_3 k59_212964_1 1279015.KB908456_gene1597 2.13e-15 89.7 COG5301@1|root,COG5301@2|Bacteria,1N4KH@1224|Proteobacteria,1RXZU@1236|Gammaproteobacteria,1Y5J9@135624|Aeromonadales 135624|Aeromonadales S Phage tail-collar fibre protein - - - - - - - - - - - - DUF3751 k59_212964_4 1224318.DT73_19010 6.99e-10 61.6 2DMUG@1|root,32TR7@2|Bacteria,1N14T@1224|Proteobacteria,1SB31@1236|Gammaproteobacteria 1236|Gammaproteobacteria S tail assembly chaperone gp38 yfdK GO:0006950,GO:0006979,GO:0008150,GO:0050896 - - - - - - - - - - Caudo_TAP k59_32223_1 1234888.K0A2R8_9VIRU 9.29e-65 211.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_115290_1 1211777.BN77_4181 9.38e-34 133.0 COG4675@1|root,COG4675@2|Bacteria,1QWQH@1224|Proteobacteria,2UUR5@28211|Alphaproteobacteria,4BFMU@82115|Rhizobiaceae 28211|Alphaproteobacteria S tail collar domain protein - - - - - - - - - - - - Collar k59_230543_2 420662.Mpe_B0362 1.06e-50 173.0 COG3206@1|root,COG3206@2|Bacteria,1ND5H@1224|Proteobacteria,2W2TN@28216|Betaproteobacteria 28216|Betaproteobacteria M protein involved in exopolysaccharide biosynthesis - - - - - - - - - - - - - k59_230543_3 1218352.B597_019615 2.15e-52 171.0 2E5K5@1|root,330BC@2|Bacteria,1RG8X@1224|Proteobacteria,1S3Z1@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Siphovirus Gp157 - - - - - - - - - - - - Sipho_Gp157 k59_230543_4 665571.STHERM_c13180 4.32e-10 59.3 COG0629@1|root,COG0629@2|Bacteria,2J7A3@203691|Spirochaetes 203691|Spirochaetes L Single-stranded DNA-binding protein - - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_148708_2 1692242.A0A0K1RKZ2_9CIRC 6.9e-42 152.0 4QFEW@10239|Viruses,4QUKZ@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_206056_6 1042377.AFPJ01000043_gene947 1.85e-12 74.3 COG2718@1|root,COG2718@2|Bacteria,1MWQM@1224|Proteobacteria,1RQWC@1236|Gammaproteobacteria,464ND@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0229 family yeaH - - ko:K09786 - - - - ko00000 - - - DUF444 k59_106525_3 177437.HRM2_40470 0.000931 42.4 COG3530@1|root,COG3530@2|Bacteria,1N7GT@1224|Proteobacteria,42V3W@68525|delta/epsilon subdivisions,2WREM@28221|Deltaproteobacteria,2MM11@213118|Desulfobacterales 28221|Deltaproteobacteria S Putative quorum-sensing-regulated virulence factor - - - ko:K09954 - - - - ko00000 - - - QSregVF_b k59_231338_1 1028801.RG1141_CH32210 8.49e-15 77.8 COG1573@1|root,COG1573@2|Bacteria,1MW8T@1224|Proteobacteria,2TSAR@28211|Alphaproteobacteria,4BD94@82115|Rhizobiaceae 28211|Alphaproteobacteria L uracil-DNA glycosylase - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - DUF4130,UDG k59_88580_1 1158294.JOMI01000007_gene779 5.22e-59 199.0 COG1783@1|root,COG1783@2|Bacteria,4NHPB@976|Bacteroidetes,2FR95@200643|Bacteroidia 976|Bacteroidetes S Phage terminase, large subunit, PBSX family - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C k59_88580_2 316274.Haur_0565 2.91e-10 64.7 COG3728@1|root,COG3728@2|Bacteria 2|Bacteria L DNA packaging xtmA - - ko:K07474 - - - - ko00000 - - - Terminase_2 k59_124311_1 1131814.JAFO01000001_gene2055 2.02e-29 123.0 COG3723@1|root,COG3723@2|Bacteria,1R6DB@1224|Proteobacteria,2U82T@28211|Alphaproteobacteria 28211|Alphaproteobacteria L RecT family - - - ko:K07455 - - - - ko00000,ko03400 - - - RecT k59_190641_2 261292.Nit79A3_1409 9.19e-61 196.0 COG0863@1|root,COG0863@2|Bacteria 2|Bacteria L N-4 methylation of cytosine - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_23264_1 136084.Q9G0G8_9CAUD 1.89e-28 114.0 4QGZN@10239|Viruses,4R0FF@35237|dsDNA viruses no RNA stage,4QTUK@28883|Caudovirales,4QNE5@10744|Podoviridae 10744|Podoviridae S nuclease activity - - - - - - - - - - - - - k59_39934_1 742740.HMPREF9474_02303 1.87e-70 241.0 2EWZQ@1|root,33QB0@2|Bacteria,1V0T1@1239|Firmicutes,249Z2@186801|Clostridia,221YV@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_156991_1 399742.Ent638_4279 3.13e-20 95.1 28H9R@1|root,2Z7MD@2|Bacteria,1MVTR@1224|Proteobacteria,1RMPH@1236|Gammaproteobacteria,3X0IF@547|Enterobacter 1236|Gammaproteobacteria S Domain of unknown function (DUF932) - - - - - - - - - - - - DUF932 k59_264709_1 313596.RB2501_01415 1.42e-58 197.0 COG1061@1|root,COG2093@1|root,COG1061@2|Bacteria,COG2093@2|Bacteria,4NECV@976|Bacteroidetes,1HXAD@117743|Flavobacteriia 976|Bacteroidetes L Domain of unknown function (DUF3427) - - - - - - - - - - - - Helicase_C,ResIII k59_206760_2 1555208.A0A097EVY8_9CAUD 1.59e-27 119.0 4QAIK@10239|Viruses,4QPEB@28883|Caudovirales,4QKNC@10699|Siphoviridae 10699|Siphoviridae S hydrolase activity - - - - - - - - - - - - - k59_213765_1 1306174.JODP01000015_gene3903 0.000319 43.5 COG0553@1|root,COG0553@2|Bacteria,2GISC@201174|Actinobacteria 201174|Actinobacteria L helicase - - - - - - - - - - - - Helicase_C,SNF2_N k59_206762_1 189425.PGRAT_19360 5.1e-43 148.0 COG0638@1|root,COG0638@2|Bacteria,1VTDM@1239|Firmicutes,4HURT@91061|Bacilli,26XQA@186822|Paenibacillaceae 91061|Bacilli O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine - - - - - - - - - - - - - k59_81745_2 1572715.A0A0A7U3D5_9CAUD 2.76e-14 73.2 4QAIU@10239|Viruses,4QPDE@28883|Caudovirales,4QKM7@10699|Siphoviridae 10699|Siphoviridae S HNH endonuclease - - - - - - - - - - - - - k59_213772_1 1430440.MGMSRv2_3278 1.05e-08 61.2 COG2071@1|root,COG2071@2|Bacteria,1MV8E@1224|Proteobacteria,2TSU3@28211|Alphaproteobacteria,2JPIW@204441|Rhodospirillales 204441|Rhodospirillales S Peptidase C26 - - - ko:K07010 - - - - ko00000,ko01002 - - - Peptidase_C26 k59_23288_1 1147150.K7PM60_9CAUD 5.44e-29 112.0 4QB1F@10239|Viruses,4QUYH@35237|dsDNA viruses no RNA stage,4QPSW@28883|Caudovirales,4QKPW@10699|Siphoviridae 10699|Siphoviridae S exonuclease activity - - - - - - - - - - - - - k59_23288_2 1247726.MIM_c10920 1.27e-28 106.0 2DM6W@1|root,32UGB@2|Bacteria,1N425@1224|Proteobacteria,2WCN3@28216|Betaproteobacteria,3T8GA@506|Alcaligenaceae 28216|Betaproteobacteria S Protein of unknown function (DUF3168) - - - - - - - - - - - - DUF3168 k59_265058_2 1100721.ALKO01000041_gene5 4.82e-73 238.0 2EZCX@1|root,33SI7@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_16547_1 260827.Q6R6A4_9CAUD 4.02e-33 138.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales 28883|Caudovirales S N-methyltransferase activity - - - - - - - - - - - - - k59_248200_1 1329516.JPST01000014_gene648 2.13e-43 166.0 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,4H9Z7@91061|Bacilli 91061|Bacilli L DNA polymerase - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_41418_2 1298858.AUEL01000029_gene80 2.14e-19 94.4 2C2IA@1|root,2ZW5P@2|Bacteria,1PB15@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_215261_1 1217714.F975_01637 3.1e-11 68.9 COG0454@1|root,COG1040@1|root,COG0456@2|Bacteria,COG1040@2|Bacteria,1QV41@1224|Proteobacteria,1RSAP@1236|Gammaproteobacteria,3NM26@468|Moraxellaceae 1236|Gammaproteobacteria K acetyltransferase - - - - - - - - - - - - - k59_265059_3 1692252.A0A0K1RL35_9CIRC 3.54e-94 288.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_215266_1 926564.KI911577_gene454 7.9e-103 324.0 COG0358@1|root,COG3378@1|root,COG0358@2|Bacteria,COG3378@2|Bacteria,2H1DT@201174|Actinobacteria 201174|Actinobacteria T Phage plasmid primase, P4 family - - - ko:K06919 - - - - ko00000 - - - D5_N,Pox_D5,Toprim_2 k59_66135_1 1609634.A0A0C5AFV4_9VIRU 1.01e-59 201.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_99207_2 675806.VII_003800 1.51e-64 200.0 COG3108@1|root,COG3108@2|Bacteria,1RICX@1224|Proteobacteria,1S5B3@1236|Gammaproteobacteria 1236|Gammaproteobacteria S D-alanyl-D-alanine carboxypeptidase - - - - - - - - - - - - Peptidase_M15_4 k59_240405_1 649831.L083_0374 9.55e-25 116.0 COG5283@1|root,COG5283@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - PhageMin_Tail k59_240405_2 742821.HMPREF9464_01823 6.32e-16 80.9 COG4228@1|root,COG4228@2|Bacteria,1R4HU@1224|Proteobacteria,2VTK2@28216|Betaproteobacteria 28216|Betaproteobacteria S DNA circularisation protein N-terminus - - - - - - - - - - - - DNA_circ_N k59_90087_1 1233488.S4T794_9CAUD 1.12e-43 157.0 4QBY0@10239|Viruses,4QQ4Q@28883|Caudovirales 28883|Caudovirales S AAA domain - - - - - - - - - - - - - k59_215553_2 2003327.CAPSD_BPCHP 7.15e-43 167.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_215564_1 392499.Swit_4443 9.17e-58 201.0 COG3170@1|root,COG3170@2|Bacteria,1QVEE@1224|Proteobacteria,2TWDG@28211|Alphaproteobacteria 28211|Alphaproteobacteria NU Phage P22-like portal protein - - - - - - - - - - - - P22_portal k59_90098_1 1121459.AQXE01000001_gene2745 2.07e-37 146.0 COG3170@1|root,COG3170@2|Bacteria,1Q45C@1224|Proteobacteria,42Z4T@68525|delta/epsilon subdivisions,2WTRW@28221|Deltaproteobacteria,2MA4T@213115|Desulfovibrionales 28221|Deltaproteobacteria NU Tfp pilus assembly protein FimV - - - - - - - - - - - - - k59_215574_1 1317118.ATO8_18655 2.03e-10 62.4 2E5ZV@1|root,330P8@2|Bacteria,1NFRE@1224|Proteobacteria,2UHQQ@28211|Alphaproteobacteria,4KNZP@93682|Roseivivax 28211|Alphaproteobacteria S Domain of unknown function (DUF1833) - - - - - - - - - - - - DUF1833 k59_248526_3 226185.EF_2126 4.41e-05 47.8 2DQDJ@1|root,3364C@2|Bacteria,1W27S@1239|Firmicutes,4HZSX@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k59_248526_5 371042.NG99_11270 1.01e-35 145.0 COG1842@1|root,COG1842@2|Bacteria,1QUUT@1224|Proteobacteria,1RPDD@1236|Gammaproteobacteria,3X58H@551|Erwinia 1236|Gammaproteobacteria KT Phage shock protein A - - - - - - - - - - - - TrbI k59_99230_1 1379720.S5TNF0_9CIRC 2.95e-35 134.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_199607_4 1300150.EMQU_0719 1.66e-06 59.7 COG3979@1|root,COG3979@2|Bacteria,1UJCX@1239|Firmicutes,4IT5P@91061|Bacilli,4B23H@81852|Enterococcaceae 91061|Bacilli S Peptidase M60-like family - - - - - - - - - - - - CBM_5_12,M60-like_N,Mucin_bdg,Peptidase_M60,fn3 k59_50282_1 942165.E9KIG9_9CAUD 6.83e-36 140.0 4QASG@10239|Viruses,4QZZU@35237|dsDNA viruses no RNA stage,4QT37@28883|Caudovirales,4QNXD@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_216274_1 225937.HP15_670 8.36e-33 130.0 COG4653@1|root,COG4653@2|Bacteria,1MWMB@1224|Proteobacteria,1S4MJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage capsid family - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_83554_1 691965.D4P7D6_9CAUD 2.62e-24 102.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_158159_3 1217708.F887_01250 4.13e-21 90.5 COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,1S26C@1236|Gammaproteobacteria,3NM7P@468|Moraxellaceae 1236|Gammaproteobacteria F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 - - iECABU_c1320.ECABU_c13120,ic_1306.c1370 Thymidylate_kin k59_17117_1 1150626.PHAMO_80072 9.24e-34 138.0 COG1783@1|root,COG1783@2|Bacteria,1R66A@1224|Proteobacteria,2TV42@28211|Alphaproteobacteria,2JXEM@204441|Rhodospirillales 204441|Rhodospirillales S Terminase-like family - - - - - - - - - - - - - k59_100178_1 420324.KI911970_gene1460 8.56e-08 64.7 COG5301@1|root,COG5301@2|Bacteria,1N4CW@1224|Proteobacteria,2TYJK@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Phage T7 tail fibre protein - - - - - - - - - - - - Phage_T7_tail k59_249434_1 395495.Lcho_0484 8.44e-39 147.0 COG2227@1|root,COG2520@1|root,COG2227@2|Bacteria,COG2520@2|Bacteria 2|Bacteria J tRNA (guanine(37)-N(1))-methyltransferase activity - - - - - - - - - - - - Glycos_transf_2,Methyltransf_11,Methyltransf_21,Methyltransf_23,Methyltransf_25 k59_150001_1 745776.DGo_CA1997 3.48e-06 57.8 COG2152@1|root,COG2152@2|Bacteria 2|Bacteria G transferase activity, transferring glycosyl groups - - - - - - - - - - - - CHU_C,Laminin_G_3 k59_257844_1 1234888.K0A2J2_9VIRU 1.38e-63 216.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_257844_3 145579.REP_BPPHM 3.19e-18 90.5 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_183773_1 1121459.AQXE01000001_gene2767 1.86e-15 74.3 COG3023@1|root,COG3023@2|Bacteria,1N032@1224|Proteobacteria,432MJ@68525|delta/epsilon subdivisions,2WX9X@28221|Deltaproteobacteria,2MCUI@213115|Desulfovibrionales 28221|Deltaproteobacteria V PFAM N-acetylmuramoyl-L-alanine amidase family 2 - - - - - - - - - - - - Amidase_2 k59_183773_6 1218075.BAYA01000001_gene421 1.07e-56 194.0 28PTM@1|root,2ZCEU@2|Bacteria,1R5DD@1224|Proteobacteria,2W259@28216|Betaproteobacteria 28216|Betaproteobacteria S Family of unknown function (DUF5309) - - - - - - - - - - - - DUF5309 k59_9538_2 1540257.JQMW01000009_gene2673 5.8e-11 62.4 2EUFA@1|root,33MXK@2|Bacteria,1VQFP@1239|Firmicutes,24S0X@186801|Clostridia,36N6B@31979|Clostridiaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_241831_1 768710.DesyoDRAFT_5152 1.21e-08 60.5 2DT4K@1|root,33INK@2|Bacteria,1VQEE@1239|Firmicutes,253M4@186801|Clostridia 1239|Firmicutes - - - - - - - - - - - - - - - k59_241831_4 1033743.CAES01000033_gene1065 5.56e-05 51.2 COG5434@1|root,COG5434@2|Bacteria 2|Bacteria M polygalacturonase activity - - - - - - - - - - - - Beta_helix,F5_F8_type_C,Laminin_G_3,Pectate_lyase_3,SLH k59_241831_5 234621.RER_07200 8.4e-98 322.0 COG1572@1|root,COG1572@2|Bacteria,2GJ8Y@201174|Actinobacteria 201174|Actinobacteria S Glycosyl hydrolase family 71 - - - - - - - - - - - - Glyco_hydro_71 k59_134324_1 4929.XP_001486882.1 4.05e-33 131.0 COG5108@1|root,KOG1038@2759|Eukaryota,38EAY@33154|Opisthokonta,3NU1C@4751|Fungi,3QN4S@4890|Ascomycota,3RS68@4891|Saccharomycetes,479W3@766764|Debaryomycetaceae 4751|Fungi KL DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates - - 2.7.7.6 ko:K10908 - - - - ko00000,ko01000,ko03029 - - - RNA_pol,RPOL_N k59_150895_1 679926.Mpet_1683 3.43e-26 110.0 COG4983@1|root,arCOG07809@2157|Archaea,2Y47N@28890|Euryarchaeota,2NB1E@224756|Methanomicrobia 224756|Methanomicrobia C Formate hydrogenlyase subunit 6 NADH ubiquinone oxidoreductase 23 kD subunit (chain I) - - - - - - - - - - - - - k59_158742_1 1125863.JAFN01000001_gene3558 4.71e-40 155.0 COG1196@1|root,COG3941@1|root,COG1196@2|Bacteria,COG3941@2|Bacteria,1RM55@1224|Proteobacteria,430PQ@68525|delta/epsilon subdivisions,2WVMQ@28221|Deltaproteobacteria 28221|Deltaproteobacteria D Prophage tail length tape measure protein - - - - - - - - - - - - TMP_2,Tape_meas_lam_C k59_117790_1 438753.AZC_3584 9.24e-46 157.0 2ATMD@1|root,31J5V@2|Bacteria,1RH31@1224|Proteobacteria,2UBNT@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Tail tubular protein - - - - - - - - - - - - Tube k59_117790_2 979535.F1D037_9CAUD 5.24e-36 152.0 4QASG@10239|Viruses,4QZZU@35237|dsDNA viruses no RNA stage,4QT37@28883|Caudovirales,4QNXD@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_217420_1 1692253.A0A0K1RLM4_9CIRC 3.42e-23 100.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_143775_4 1094184.KWO_0108105 6.81e-33 122.0 2EKAP@1|root,33E0Y@2|Bacteria,1NAAI@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_209308_1 1618247.A0A0C5IMK7_9CIRC 3.89e-05 50.8 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_135306_1 1117647.M5M_11930 4.6e-05 56.2 COG2304@1|root,COG2304@2|Bacteria,1PDQV@1224|Proteobacteria,1RPGD@1236|Gammaproteobacteria,1J904@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria V Integrin alpha (beta-propellor repeats). - - - - - - - - - - - - DUF5011,FG-GAP_2 k59_168556_1 1385658.U5KPZ6_9VIRU 7.22e-158 466.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_168556_5 1609634.A0A0C5AFT2_9VIRU 2.88e-34 133.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_43932_1 1403946.Q615_SPAC00127G0145 2.23e-06 48.1 2EI4V@1|root,33BW7@2|Bacteria,1VKQH@1239|Firmicutes,4HRPN@91061|Bacilli 91061|Bacilli S Protein of unknwon function (DUF3310) - - - - - - - - - - - - DUF3310 k59_93411_1 314285.KT71_002369 1.01e-12 67.8 COG0582@1|root,COG0582@2|Bacteria,1MXUB@1224|Proteobacteria,1RPVR@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Integrase_1,Phage_int_SAM_2 k59_201400_2 1234888.K0A2J2_9VIRU 1.05e-129 388.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_35628_2 1122225.AULQ01000001_gene1526 0.000232 52.0 COG1345@1|root,COG1361@1|root,COG1404@1|root,COG3227@1|root,COG3897@1|root,COG1345@2|Bacteria,COG1361@2|Bacteria,COG1404@2|Bacteria,COG3227@2|Bacteria,COG3897@2|Bacteria 2|Bacteria P peptidase activity, acting on L-amino acid peptides - - - - - - - - - - - - DUF1573,Laminin_G_3,MAM,Peptidase_M8,SLH k59_119230_1 1692249.A0A0K1RL40_9CIRC 8.65e-47 164.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_218813_1 78245.Xaut_4480 2.65e-08 62.4 COG4675@1|root,COG4675@2|Bacteria,1PE25@1224|Proteobacteria,2V8UM@28211|Alphaproteobacteria,3F1UP@335928|Xanthobacteraceae 28211|Alphaproteobacteria S tail collar domain protein - - - - - - - - - - - - - k59_143932_2 754331.AEME01000001_gene3537 3.05e-24 100.0 COG3926@1|root,COG3926@2|Bacteria,1MVXW@1224|Proteobacteria,1RRB6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S secretion activating protein - - - - - - - - - - - - Glyco_hydro_108,PG_binding_3 k59_110467_1 1175654.A0A0S0N897_9CAUD 1.06e-33 129.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QM52@10699|Siphoviridae 10699|Siphoviridae S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor - - - - - - - - - - - - - k59_110467_3 1244869.H261_16912 1.11e-28 118.0 COG2404@1|root,COG2404@2|Bacteria,1MXEH@1224|Proteobacteria,2U76B@28211|Alphaproteobacteria 28211|Alphaproteobacteria S phosphoesterase DHHA1 - - - - - - - - - - - - DHHA1 k59_192772_3 1123227.KB899344_gene1958 3.25e-09 60.5 COG1216@1|root,COG1216@2|Bacteria,1R554@1224|Proteobacteria,2U3P6@28211|Alphaproteobacteria,2JT5C@204441|Rhodospirillales 204441|Rhodospirillales S Glycosyl transferase, family 2 - - - - - - - - - - - - - k59_53996_3 1115512.EH105704_01_02770 1.24e-33 128.0 COG0629@1|root,COG0629@2|Bacteria,1RC22@1224|Proteobacteria,1S2A9@1236|Gammaproteobacteria 1236|Gammaproteobacteria L ERF superfamily - - - - - - - - - - - - ERF k59_53996_4 1121366.KB892443_gene1946 2.6e-12 68.6 COG0629@1|root,COG0629@2|Bacteria,2GMM3@201174|Actinobacteria,22K8T@1653|Corynebacteriaceae 201174|Actinobacteria L Single-stranded DNA-binding protein ssb GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0033554,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071944,GO:0097159,GO:1901363 - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_203023_1 2003327.CAPSD_BPCHP 2.01e-17 88.2 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_194044_3 1227497.C491_00892 2.75e-31 135.0 COG0210@1|root,arCOG00797@2157|Archaea,2XUH7@28890|Euryarchaeota,23S3W@183963|Halobacteria 183963|Halobacteria L COG0210 Superfamily I DNA and RNA helicases uvrD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k59_53999_2 759938.F5BSB4_9CIRC 1.32e-24 107.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_29148_1 485918.Cpin_3834 1.29e-58 189.0 COG0270@1|root,COG0270@2|Bacteria,4NRFG@976|Bacteroidetes,1IY5U@117747|Sphingobacteriia 976|Bacteroidetes L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_203028_2 1234888.K0A2J2_9VIRU 4.76e-43 155.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_112063_1 935261.JAGL01000009_gene1168 1.32e-55 181.0 COG1351@1|root,COG1351@2|Bacteria,1MWY8@1224|Proteobacteria,2TTER@28211|Alphaproteobacteria,43QDX@69277|Phyllobacteriaceae 28211|Alphaproteobacteria F Thymidylate synthase complementing protein thyX - 2.1.1.148 ko:K03465 ko00240,ko00670,ko01100,map00240,map00670,map01100 - R06613 RC00022,RC00332 ko00000,ko00001,ko01000 - - - Thy1 k59_252062_1 1029823.AFIE01000007_gene1881 0.0 1211.0 COG0454@1|root,COG0553@1|root,COG0827@1|root,COG1040@1|root,COG4646@1|root,COG0456@2|Bacteria,COG0553@2|Bacteria,COG0827@2|Bacteria,COG1040@2|Bacteria,COG4646@2|Bacteria,1MXQH@1224|Proteobacteria,1T52I@1236|Gammaproteobacteria,3NTTI@468|Moraxellaceae 1236|Gammaproteobacteria L methylase - - - - - - - - - - - - - k59_178053_1 1235661.K0IMS6_9CAUD 1.8e-24 109.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_210569_1 316275.VSAL_I0780 7.49e-10 58.2 2CPEB@1|root,32SIW@2|Bacteria,1MZE0@1224|Proteobacteria,1SARU@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_11968_1 94624.Bpet1003 1.71e-27 105.0 COG3772@1|root,COG3772@2|Bacteria,1N0ZQ@1224|Proteobacteria,2VVDM@28216|Betaproteobacteria 28216|Betaproteobacteria S lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_113593_2 504346.B5WZW3_BPPAJ 7.2e-23 95.5 4QCB0@10239|Viruses,4QX81@35237|dsDNA viruses no RNA stage,4QPFH@28883|Caudovirales,4QKQY@10699|Siphoviridae 10699|Siphoviridae S YqaJ-like viral recombinase domain - - - - - - - - - - - - - k59_229166_5 314225.ELI_11110 3.81e-56 181.0 COG0739@1|root,COG0739@2|Bacteria 2|Bacteria M heme binding - - - - - - - - - - - - Cu_amine_oxidN1,Peptidase_M23 k59_13000_1 411479.BACUNI_00947 1.23e-11 69.3 COG3677@1|root,COG3677@2|Bacteria,4NJC5@976|Bacteroidetes,2G2VB@200643|Bacteroidia,4AQ5E@815|Bacteroidaceae 976|Bacteroidetes L COG NOG14720 non supervised orthologous group - - - - - - - - - - - - DDE_Tnp_IS1595,Zn_Tnp_IS1595 k59_113597_1 1183438.GKIL_0426 5.68e-17 84.7 COG4712@1|root,COG4712@2|Bacteria 2|Bacteria S DNA recombination - - - - - - - - - - - - Rad52_Rad22 k59_179214_2 500637.PROVRUST_05413 4.68e-06 47.0 COG3179@1|root,COG3179@2|Bacteria,1RE8K@1224|Proteobacteria,1S4U8@1236|Gammaproteobacteria,3Z9BP@586|Providencia 1236|Gammaproteobacteria S D-alanyl-D-alanine carboxypeptidase - - - - - - - - - - - - Peptidase_M15_4 k59_229169_1 691965.D4P7C5_9CAUD 2.93e-279 774.0 4QBV3@10239|Viruses,4QW0W@35237|dsDNA viruses no RNA stage,4QPPJ@28883|Caudovirales,4QKW5@10699|Siphoviridae 10699|Siphoviridae S Phage Terminase - - - - - - - - - - - - - k59_30493_1 888049.HMPREF8578_0275 1.06e-21 97.4 COG0270@1|root,COG0270@2|Bacteria,1UWG9@1239|Firmicutes,4I47C@91061|Bacilli,1WQ32@1303|Streptococcus oralis 91061|Bacilli H C-5 cytosine-specific DNA methylase - - - - - - - - - - - - DNA_methylase k59_195255_1 1121413.JMKT01000014_gene2557 3.12e-27 114.0 COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,42QJ2@68525|delta/epsilon subdivisions,2WM78@28221|Deltaproteobacteria,2M8CT@213115|Desulfovibrionales 28221|Deltaproteobacteria S VWA-like domain (DUF2201) - - - - - - - - - - - - DUF2201,DUF2201_N k59_30658_1 490913.C4NTD5_9CAUD 4.88e-119 364.0 4QGA5@10239|Viruses,4QURD@35237|dsDNA viruses no RNA stage,4QT9N@28883|Caudovirales,4QP47@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_30658_2 1477404.A0A023NGB4_9CAUD 1.04e-77 239.0 4QEMD@10239|Viruses,4R0JN@35237|dsDNA viruses no RNA stage,4QUGF@28883|Caudovirales,4QNXF@10744|Podoviridae 10744|Podoviridae S AAA domain - - - - - - - - - - - - - k59_13070_1 305900.GV64_08545 1.66e-25 108.0 COG0433@1|root,COG0433@2|Bacteria,1QTVP@1224|Proteobacteria,1T1IQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Zonular occludens toxin (Zot) - - - ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko02042 - - - Zot k59_20957_1 1449063.JMLS01000001_gene4318 2.32e-26 116.0 COG2366@1|root,COG3386@1|root,COG3420@1|root,COG5492@1|root,COG2366@2|Bacteria,COG3386@2|Bacteria,COG3420@2|Bacteria,COG5492@2|Bacteria,1VR20@1239|Firmicutes,4HVGA@91061|Bacilli,26V79@186822|Paenibacillaceae 91061|Bacilli P Right handed beta helix region - - - - - - - - - - - - Beta_helix,Big_2 k59_195378_3 1042209.HK44_020560 4.56e-19 85.1 2CYA9@1|root,32T3V@2|Bacteria,1RGRN@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_30659_1 742740.HMPREF9474_02272 4.92e-80 255.0 COG4626@1|root,COG4626@2|Bacteria,1TT9I@1239|Firmicutes,24AFK@186801|Clostridia,222GA@1506553|Lachnoclostridium 186801|Clostridia S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_20959_1 1502724.FF80_03293 8.15e-06 48.5 COG0582@1|root,COG0582@2|Bacteria,1NH8M@1224|Proteobacteria,2TUHG@28211|Alphaproteobacteria,3N6X7@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_integrase k59_155010_2 1278073.MYSTI_01949 4.36e-14 75.1 COG3598@1|root,COG4643@1|root,COG3598@2|Bacteria,COG4643@2|Bacteria,1R6M4@1224|Proteobacteria 1224|Proteobacteria L Phage plasmid primase P4 family - - - ko:K06919 - - - - ko00000 - - - PriCT_2,Prim-Pol k59_147273_2 667632.KB890187_gene3034 1.91e-13 68.2 COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,2VSKJ@28216|Betaproteobacteria,1K8EE@119060|Burkholderiaceae 28216|Betaproteobacteria O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS - - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 k59_104608_2 1484158.PSNIH1_00390 4.91e-09 58.5 2BMAA@1|root,32FU7@2|Bacteria,1Q0QX@1224|Proteobacteria,1TE0I@1236|Gammaproteobacteria,3W2IF@53335|Pantoea 1236|Gammaproteobacteria S HNH endonuclease - - - - - - - - - - - - HNH_3 k59_162514_2 857293.CAAU_0781 2.12e-80 258.0 COG3723@1|root,COG3723@2|Bacteria,1UNDF@1239|Firmicutes,24ECD@186801|Clostridia,36HN4@31979|Clostridiaceae 186801|Clostridia L RecT family - - - ko:K07455 - - - - ko00000,ko03400 - - - RecT k59_229309_1 1357423.S5MAX6_9CAUD 4.11e-19 92.8 4QCR0@10239|Viruses,4QVAV@35237|dsDNA viruses no RNA stage,4QPFK@28883|Caudovirales,4QI4N@10662|Myoviridae 10662|Myoviridae S cell wall macromolecule catabolic process - GO:0003674,GO:0003796,GO:0003824,GO:0004553,GO:0005488,GO:0005515,GO:0005575,GO:0008150,GO:0009405,GO:0009987,GO:0016043,GO:0016787,GO:0016798,GO:0019012,GO:0022607,GO:0033922,GO:0042802,GO:0043933,GO:0044085,GO:0044403,GO:0044409,GO:0044411,GO:0044419,GO:0044423,GO:0051259,GO:0051260,GO:0051701,GO:0051704,GO:0051828,GO:0051830,GO:0061783,GO:0065003,GO:0070206,GO:0070207,GO:0071840,GO:0085027,GO:0098015,GO:0098025 - - - - - - - - - - - k59_230404_1 642492.Clole_0830 3.72e-36 144.0 COG5283@1|root,COG5412@1|root,COG5283@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes 1239|Firmicutes D Phage tail tape measure protein, TP901 family - - - - - - - - - - - - PhageMin_Tail k59_96863_1 105154.Q9MBU6_9VIRU 2.36e-71 235.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_139894_2 1618238.A0A0C5I2G8_9CIRC 1.41e-36 137.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_139894_3 1234880.K0A2H8_9CIRC 9.52e-24 106.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_22412_1 1443665.JACA01000052_gene1878 2.23e-09 65.1 COG0726@1|root,COG2730@1|root,COG3250@1|root,COG4733@1|root,COG0726@2|Bacteria,COG2730@2|Bacteria,COG3250@2|Bacteria,COG4733@2|Bacteria,4NIBG@976|Bacteroidetes,1HYT8@117743|Flavobacteriia,2YJTE@290174|Aquimarina 976|Bacteroidetes G Cellulase (glycosyl hydrolase family 5) - - 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 - R06200,R11307,R11308 - ko00000,ko00001,ko01000 - GH5,GH9 - CBM_6,Cellulase,F5_F8_type_C,fn3 k59_96948_1 1618248.A0A0C5IB82_9CIRC 4.96e-08 61.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_32193_1 765910.MARPU_09550 1.28e-49 176.0 COG4653@1|root,COG4653@2|Bacteria,1MWMB@1224|Proteobacteria,1S4MJ@1236|Gammaproteobacteria,1X0RU@135613|Chromatiales 135613|Chromatiales S Phage capsid family - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_115266_1 1328313.DS2_10943 1.7e-27 114.0 COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,1RMJ0@1236|Gammaproteobacteria,46A2N@72275|Alteromonadaceae 1236|Gammaproteobacteria P Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Sulfatase k59_32195_1 411483.FAEPRAA2165_01911 3.57e-14 78.2 COG5283@1|root,COG5412@1|root,COG5283@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,247QT@186801|Clostridia,3WH3F@541000|Ruminococcaceae 186801|Clostridia E Phage tail tape measure protein, TP901 family - - - - - - - - - - - - PhageMin_Tail,TMP k59_22415_3 1121373.KB903654_gene1525 2.56e-11 63.2 2DMPB@1|root,32SV8@2|Bacteria,4NSG4@976|Bacteroidetes,47SFC@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_180741_1 1636270.A0A0E3JSA3_9CAUD 4.14e-10 66.6 4QB5I@10239|Viruses,4QPQ9@28883|Caudovirales,4QNNS@10744|Podoviridae 10744|Podoviridae S SNF2 family N-terminal domain - - - - - - - - - - - - - k59_173189_1 1618242.A0A0C5IBR9_9CIRC 1.2e-21 98.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_88045_1 1237149.C900_00167 0.000208 52.4 COG1044@1|root,COG1044@2|Bacteria,4PNZT@976|Bacteroidetes 976|Bacteroidetes M chitinase - - - - - - - - - - - - - k59_156398_6 1234888.K0A2J2_9VIRU 3.21e-161 473.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_156398_7 1385658.U5KNR1_9VIRU 0.000313 48.5 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_148690_3 105154.Q9MBU6_9VIRU 1.32e-226 643.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_163758_2 1609634.A0A0C5ANA6_9VIRU 1.31e-09 58.9 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_173199_1 1458462.JNLK01000001_gene353 1.56e-17 86.3 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,2487V@186801|Clostridia,27JEU@186928|unclassified Lachnospiraceae 186801|Clostridia L DNA polymerase A domain - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_206892_2 1618248.A0A0C5IB82_9CIRC 3.07e-11 65.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_132494_1 1609634.A0A0C5AFV4_9VIRU 5.08e-24 107.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_247017_1 314275.MADE_000001022545 1.14e-97 303.0 COG0553@1|root,COG0553@2|Bacteria,1MV6M@1224|Proteobacteria,1RQ34@1236|Gammaproteobacteria,465QU@72275|Alteromonadaceae 1236|Gammaproteobacteria KL SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,Mrr_cat,SNF2_N,SWIM k59_164898_1 588581.Cpap_1262 5.49e-16 79.7 292XD@1|root,2ZQEV@2|Bacteria,1V48I@1239|Firmicutes,24GZD@186801|Clostridia 186801|Clostridia S COG NOG18825 non supervised orthologous group - - - - - - - - - - - - - k59_140890_3 65393.PCC7424_0393 1.84e-48 156.0 COG1943@1|root,COG1943@2|Bacteria,1G73H@1117|Cyanobacteria 1117|Cyanobacteria L COG1943 Transposase and inactivated derivatives - - - ko:K07491 - - - - ko00000 - - - Y1_Tnp k59_213949_1 867902.Ornrh_2251 7.14e-121 365.0 COG5362@1|root,COG5362@2|Bacteria,4NGC4@976|Bacteroidetes,1I0YX@117743|Flavobacteriia 976|Bacteroidetes S TIGRFAM Phage - - - - - - - - - - - - - k59_57756_1 1064535.MELS_0539 1.16e-05 53.9 COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,4H2P0@909932|Negativicutes 909932|Negativicutes K Belongs to the ParB family spo0J - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_181816_2 1121033.AUCF01000011_gene1828 5.2e-23 105.0 COG1573@1|root,COG1573@2|Bacteria 2|Bacteria L deaminated base DNA N-glycosylase activity - - - - - - - - - - - - UDG k59_181819_1 1609634.A0A0C5AFV4_9VIRU 2.27e-47 169.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_97980_1 272568.GDI3678 4.98e-25 108.0 28MJ5@1|root,2ZAVR@2|Bacteria,1R5CR@1224|Proteobacteria,2UAIJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - Phage_stabilise k59_265165_1 1618248.A0A0C5IB82_9CIRC 2.09e-58 191.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_265165_3 742918.D4N3P2_9CIRC 5.94e-14 74.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_248757_1 1379692.S5SXY7_9CIRC 6.88e-16 80.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_257194_4 318586.Pden_3765 1.06e-32 116.0 2D1MV@1|root,32TAZ@2|Bacteria,1N45A@1224|Proteobacteria,2UEJT@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Phage protein (N4 Gp49/phage Sf6 gene 66) family - - - - - - - - - - - - Phage_gp49_66 k59_107927_1 1385658.U5KPZ6_9VIRU 2.17e-27 111.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_107927_6 1385658.U5KPZ6_9VIRU 1.14e-44 162.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_8433_3 403833.Pmob_0010 8.76e-10 54.3 COG1278@1|root,COG1278@2|Bacteria,2GDFN@200918|Thermotogae 200918|Thermotogae K PFAM Cold-shock protein, DNA-binding - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD k59_240571_2 156889.Mmc1_1012 2.41e-43 169.0 COG2268@1|root,COG2268@2|Bacteria,1NT13@1224|Proteobacteria,2U335@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Band 7 protein - - - - - - - - - - - - - k59_99591_3 290315.Clim_2149 3.38e-16 77.4 COG0629@1|root,COG0629@2|Bacteria,1FE0M@1090|Chlorobi 1090|Chlorobi L PFAM single-strand binding protein Primosomal replication protein n - - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_182531_3 948071.S4S2J9_9CAUD 3.58e-34 130.0 4QB79@10239|Viruses,4QX2S@35237|dsDNA viruses no RNA stage,4QS2C@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_133637_1 1385658.U5KPZ6_9VIRU 1.77e-23 100.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_75574_3 742159.HMPREF0004_2547 9.82e-38 134.0 2C2XN@1|root,32GT6@2|Bacteria,1REZE@1224|Proteobacteria,2VQSN@28216|Betaproteobacteria,3T7WM@506|Alcaligenaceae 28216|Betaproteobacteria S ERF superfamily - - - - - - - - - - - - ERF k59_183323_1 742733.HMPREF9469_05020 2.3e-52 187.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia,221IX@1506553|Lachnoclostridium 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_183323_2 691965.D4P7E5_9CAUD 6.29e-38 131.0 4QEVD@10239|Viruses,4QW84@35237|dsDNA viruses no RNA stage,4QQSX@28883|Caudovirales,4QMU4@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_183323_5 428125.CLOLEP_01417 4.71e-49 164.0 2CGG9@1|root,2ZVSJ@2|Bacteria,1V633@1239|Firmicutes,24HD0@186801|Clostridia,3WMXK@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_183323_6 742733.HMPREF9469_05026 1.33e-85 260.0 28NM4@1|root,2ZBMQ@2|Bacteria,1V1QD@1239|Firmicutes,24G1B@186801|Clostridia,221N8@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_183323_7 691965.D4P7D8_9CAUD 4.27e-39 132.0 4QBBW@10239|Viruses,4QXCP@35237|dsDNA viruses no RNA stage,4QQ3N@28883|Caudovirales,4QN1X@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_183323_8 411460.RUMTOR_01344 1.01e-37 129.0 2E2Y0@1|root,32XYV@2|Bacteria,1VD9S@1239|Firmicutes,24PK0@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_183323_9 691965.D4P7D6_9CAUD 7.51e-174 516.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_83721_2 105154.Q9MBU3_9VIRU 2.24e-13 73.6 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_174740_1 1220601.L7TLX3_9CAUD 1.33e-57 196.0 4QF7H@10239|Viruses,4R06M@35237|dsDNA viruses no RNA stage,4QQTS@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_258143_2 1385658.U5KNR1_9VIRU 9.65e-75 239.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_258143_4 1385658.U5KPZ6_9VIRU 1.12e-205 589.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_67217_2 1564096.A0A0A0YSL6_9CAUD 2.09e-09 59.3 4QB1M@10239|Viruses,4QSJV@28883|Caudovirales,4QIPX@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_116999_1 1234888.K0A2J2_9VIRU 1.21e-93 295.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_116999_3 913970.F8RW84_9VIRU 3.08e-08 62.4 4QCVK@10239|Viruses,4QUMV@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_116999_6 2003327.CAPSD_BPCHP 1.6e-16 83.2 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_141994_2 596151.DesfrDRAFT_0052 2.73e-07 53.9 2A4UU@1|root,30TGD@2|Bacteria,1PDAV@1224|Proteobacteria,43EV9@68525|delta/epsilon subdivisions,2X1YA@28221|Deltaproteobacteria,2MFV0@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_17260_7 1510531.JQJJ01000011_gene2883 3.94e-19 90.9 COG3179@1|root,COG3179@2|Bacteria,1R71F@1224|Proteobacteria,2V8ZW@28211|Alphaproteobacteria,3K5PW@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S chitinase - - - - - - - - - - - - - k59_75588_2 1118054.CAGW01000095_gene4680 5.07e-11 60.1 2EI4V@1|root,33BW7@2|Bacteria,1VKQH@1239|Firmicutes,4HRPN@91061|Bacilli 91061|Bacilli S Protein of unknwon function (DUF3310) - - - - - - - - - - - - DUF3310 k59_92302_1 529929.B3FYJ5_9CAUD 3.15e-130 400.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_26859_2 663932.KB902575_gene2864 4.58e-19 91.3 COG1216@1|root,COG1216@2|Bacteria,1R554@1224|Proteobacteria,2U3P6@28211|Alphaproteobacteria,2JT5C@204441|Rhodospirillales 204441|Rhodospirillales S Glycosyl transferase, family 2 - - - - - - - - - - - - - k59_26859_3 1120705.FG95_01139 4.18e-12 74.3 COG1216@1|root,COG1216@2|Bacteria,1R554@1224|Proteobacteria,2U3P6@28211|Alphaproteobacteria,2K9SK@204457|Sphingomonadales 204457|Sphingomonadales S Glycosyl transferase, family 2 - - - - - - - - - - - - Glyco_tranf_2_3 k59_242066_2 1220601.L7TLW7_9CAUD 2.53e-20 94.7 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales 28883|Caudovirales S N-acetylmuramoyl-L-alanine amidase activity - - - - - - - - - - - - - k59_109462_1 517418.Ctha_0275 2.82e-23 94.0 2CPEB@1|root,32SIW@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Peptidase_M15_4 k59_26862_1 1123257.AUFV01000013_gene2790 5.61e-12 68.2 COG4373@1|root,COG4373@2|Bacteria,1N2KG@1224|Proteobacteria,1RNKU@1236|Gammaproteobacteria,1X910@135614|Xanthomonadales 135614|Xanthomonadales S Mu-like prophage FluMu protein gp28 - - - - - - - - - - - - - k59_167711_1 1411685.U062_00586 1.12e-15 77.0 COG0433@1|root,COG0433@2|Bacteria,1QTVP@1224|Proteobacteria,1T1IQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Zonular occludens toxin (Zot) - - - ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko02042 - - - Zot k59_167711_2 1437882.AZRU01000135_gene1132 1.31e-06 50.4 2ARMS@1|root,31GYF@2|Bacteria,1QEMU@1224|Proteobacteria,1TBE6@1236|Gammaproteobacteria,1YH9I@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Protein of unknown function (DUF2523) - - - - - - - - - - - - DUF2523 k59_167802_6 908819.A0A0A0YQA8_9CAUD 3.32e-13 68.2 4QAQV@10239|Viruses,4QUPK@35237|dsDNA viruses no RNA stage,4QPCB@28883|Caudovirales,4QHX6@10662|Myoviridae 10662|Myoviridae S hydrolase activity - - - - - - - - - - - - - k59_143008_1 716541.ECL_03186 1.16e-09 65.9 COG3096@1|root,COG5281@1|root,COG3096@2|Bacteria,COG5281@2|Bacteria,1MX2R@1224|Proteobacteria,1RS2K@1236|Gammaproteobacteria,3X181@547|Enterobacter 1236|Gammaproteobacteria D tape measure protein - - - - - - - - - - - - Phage_HK97_TLTM k59_159000_4 926562.Oweho_3190 3.92e-75 232.0 COG0393@1|root,COG0393@2|Bacteria,4NS20@976|Bacteroidetes,1I4ZC@117743|Flavobacteriia 976|Bacteroidetes S Belongs to the UPF0145 family - - - - - - - - - - - - YbjQ_1 k59_126445_1 1219035.NT2_13_00580 2.11e-07 53.5 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_192161_1 1209989.TepiRe1_1126 2.46e-15 77.8 2C9JF@1|root,32RPD@2|Bacteria,1VC16@1239|Firmicutes,24RAH@186801|Clostridia,42IR8@68295|Thermoanaerobacterales 186801|Clostridia S ERF superfamily - - - - - - - - - - - - ERF k59_34993_2 1520935.A0A0H3UB63_9CIRC 4.48e-21 99.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_225870_1 1235792.C808_02259 8.56e-21 89.7 COG4725@1|root,COG4725@2|Bacteria,1TSJV@1239|Firmicutes,248X5@186801|Clostridia,27KVV@186928|unclassified Lachnospiraceae 186801|Clostridia KT MT-A70 - - - - - - - - - - - - MT-A70 k59_225870_3 1229909.NSED_08385 2.82e-14 68.6 COG1522@1|root,arCOG01117@2157|Archaea 2157|Archaea K COG1522 Transcriptional regulators - - - - - - - - - - - - AsnC_trans_reg k59_260345_1 2003327.CAPSD_BPCHP 5.19e-55 191.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_10901_1 1121413.JMKT01000010_gene744 1.13e-07 57.8 COG1205@1|root,COG1205@2|Bacteria,1QU0I@1224|Proteobacteria,42M4R@68525|delta/epsilon subdivisions,2WK1V@28221|Deltaproteobacteria,2M8EC@213115|Desulfovibrionales 28221|Deltaproteobacteria L DEAD DEAH box helicase domain protein yprA - - ko:K06877 - - - - ko00000 - - - DEAD,DUF1998,Helicase_C,RNase_H_2 k59_19075_1 1122970.AUHC01000004_gene2398 1.35e-05 47.0 2E46I@1|root,332Q5@2|Bacteria,1NFBY@1224|Proteobacteria,2UFWQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_36038_1 1114179.I2FLT9_9CAUD 2.6e-43 157.0 4QD9Y@10239|Viruses,4R02G@35237|dsDNA viruses no RNA stage,4QS1V@28883|Caudovirales,4QNWZ@10744|Podoviridae 10744|Podoviridae S Terminase-like family - - - - - - - - - - - - - k59_219434_3 1986029.Q9MBM3_9VIRU 2.32e-35 134.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_60655_1 1234888.K0A2J2_9VIRU 8.2e-66 217.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_28344_1 1279017.AQYJ01000026_gene5 1.12e-34 123.0 2AD08@1|root,312N7@2|Bacteria,1NDC4@1224|Proteobacteria,1SAPT@1236|Gammaproteobacteria,467W0@72275|Alteromonadaceae 1236|Gammaproteobacteria S Holin of 3TMs, for gene-transfer release - - - - - - - - - - - - GTA_holin_3TM k59_3448_1 205914.HS_1377 3.01e-43 150.0 28W6R@1|root,2ZI7D@2|Bacteria,1N49N@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_102515_1 1158318.ATXC01000001_gene927 1.27e-12 65.1 COG0234@1|root,COG0234@2|Bacteria,2G44S@200783|Aquificae 200783|Aquificae O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 k59_219436_1 1692259.A0A0K1RL59_9CIRC 2.6e-15 77.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_219440_2 145579.CAPSD_BPPHM 1.25e-76 246.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_85228_7 202954.BBNK01000010_gene1458 3.36e-19 84.0 2AJ1X@1|root,319K5@2|Bacteria,1RK0X@1224|Proteobacteria,1SG38@1236|Gammaproteobacteria,3NPGD@468|Moraxellaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF2829) - - - - - - - - - - - - DUF2829 k59_85228_9 1096546.WYO_0201 1.65e-35 138.0 28P6A@1|root,2ZC10@2|Bacteria,1RBZE@1224|Proteobacteria,2UQEG@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_28348_1 697282.Mettu_0967 8.17e-09 63.2 2DSWE@1|root,33HPD@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_161661_2 1692257.A0A0K1RL39_9CIRC 2.5e-96 293.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_137361_1 665956.HMPREF1032_00686 1.47e-38 148.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia,3WN92@541000|Ruminococcaceae 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_261796_1 349521.HCH_04545 1.6e-17 92.8 COG5283@1|root,COG5283@2|Bacteria,1QZAD@1224|Proteobacteria,1RYP3@1236|Gammaproteobacteria,1XMG9@135619|Oceanospirillales 135619|Oceanospirillales D nuclear chromosome segregation - - - - - - - - - - - - - k59_29852_1 1476888.X4YGV5_9CAUD 2.38e-05 52.8 4QF5E@10239|Viruses,4R01K@35237|dsDNA viruses no RNA stage,4QS4R@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_95226_1 1126411.I1TEL3_9CIRC 2.38e-36 136.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_20434_1 1609634.A0A0C5ANA6_9VIRU 1.3e-24 102.0 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_261801_1 1117958.PE143B_0129530 2.72e-20 95.1 28KYW@1|root,2ZAE8@2|Bacteria,1MX3D@1224|Proteobacteria,1RQQR@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4055) - - - - - - - - - - - - DUF4055 k59_137482_5 1122201.AUAZ01000017_gene2950 1.04e-70 230.0 COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,1RY1X@1236|Gammaproteobacteria,46BED@72275|Alteromonadaceae 1236|Gammaproteobacteria S associated with various cellular activities - - - - - - - - - - - - AAA,AAA_5 k59_212368_1 1609634.A0A0C5ANA6_9VIRU 6.1e-24 97.4 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_212368_2 1609634.A0A0C5AFV4_9VIRU 5.83e-133 394.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_55905_2 105154.Q9MBU2_9VIRU 2.58e-13 70.9 4QDBB@10239|Viruses,4QUM0@29258|ssDNA viruses,4QP4D@10841|Microviridae 10841|Microviridae S Chlamydia-phage Chp2 scaffold (Chlamy_scaf) - - - - - - - - - - - - - k59_172334_1 1115515.EV102420_11_00070 1.51e-18 88.6 COG2911@1|root,COG5281@1|root,COG2911@2|Bacteria,COG5281@2|Bacteria 2|Bacteria D sister chromatid segregation - - - - - - - - - - - - Phage_HK97_TLTM,SLT,Tape_meas_lam_C k59_139108_1 1561998.Csp11.Scaffold626.g6580.t2 5.79e-06 54.3 KOG2373@1|root,KOG2373@2759|Eukaryota,38EP4@33154|Opisthokonta,3BFTP@33208|Metazoa,3CVJJ@33213|Bilateria,40FFR@6231|Nematoda,1KXQA@119089|Chromadorea,40UYR@6236|Rhabditida 33208|Metazoa L DnaB-like helicase C terminal domain C10orf2 GO:0000002,GO:0000959,GO:0002020,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003690,GO:0003697,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006264,GO:0006268,GO:0006351,GO:0006390,GO:0006725,GO:0006807,GO:0006996,GO:0007005,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0018130,GO:0019438,GO:0019899,GO:0022607,GO:0031974,GO:0032042,GO:0032392,GO:0032508,GO:0032774,GO:0034214,GO:0034641,GO:0034645,GO:0034654,GO:0042645,GO:0043139,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0048037,GO:0051259,GO:0051260,GO:0051276,GO:0051536,GO:0051537,GO:0051540,GO:0065003,GO:0070013,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097659,GO:0140053,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - AAA_25 k59_13547_2 1986029.Q9MBM3_9VIRU 2.91e-21 95.1 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_163092_1 1692242.A0A0K1RKZ2_9CIRC 4.95e-20 94.0 4QFEW@10239|Viruses,4QUKZ@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_188804_1 105154.Q9MBU2_9VIRU 0.000876 45.1 4QDBB@10239|Viruses,4QUM0@29258|ssDNA viruses,4QP4D@10841|Microviridae 10841|Microviridae S Chlamydia-phage Chp2 scaffold (Chlamy_scaf) - - - - - - - - - - - - - k59_105223_1 1000565.METUNv1_00550 6.33e-43 170.0 COG4733@1|root,COG4733@2|Bacteria,1R7KR@1224|Proteobacteria,2VQCZ@28216|Betaproteobacteria 28216|Betaproteobacteria S COG4733 Phage-related protein, tail component - - - - - - - - - - - - Phage-tail_3 k59_31426_1 1416759.AYMR01000009_gene3060 5.8e-16 78.2 COG4675@1|root,COG4675@2|Bacteria,2IIYR@201174|Actinobacteria 201174|Actinobacteria S Phage Tail Collar Domain - - - - - - - - - - - - Collar k59_172340_1 1498011.A0A096XUX6_9CAUD 1.65e-57 199.0 4QCZC@10239|Viruses,4QRH3@28883|Caudovirales 28883|Caudovirales S Bacterial DNA polymerase III alpha subunit - - - - - - - - - - - - - k59_188810_2 97139.C824_05152 4.16e-24 105.0 COG0535@1|root,COG0535@2|Bacteria,1V348@1239|Firmicutes,24GVU@186801|Clostridia 186801|Clostridia C Radical SAM superfamily - - - - - - - - - - - - Fer4_12,Radical_SAM,SPASM k59_7132_1 1327970.R9ZWA8_9CAUD 6.36e-15 79.3 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - GO:0008150,GO:0044403,GO:0044409,GO:0044411,GO:0044419,GO:0051701,GO:0051704,GO:0051828,GO:0051830,GO:0085027 - - - - - - - - - - - k59_163257_2 1862824.A0A193CEB8_9VIRU 5.18e-22 89.7 4QB6C@10239|Viruses 10239|Viruses L Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_163257_3 1795991.A0A140CTS1_9CIRC 2.99e-26 111.0 4QHM9@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_777_2 1788454.A0A190WHE4_9CIRC 1.13e-18 91.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_207905_2 1692257.A0A0K1RL39_9CIRC 2.12e-81 255.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_207905_3 1692242.A0A0K1RKZ2_9CIRC 1.48e-08 60.5 4QFEW@10239|Viruses,4QUKZ@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_232931_1 1692250.A0A0K1RLR1_9CIRC 7.4e-74 239.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_158174_1 105154.Q9MBU0_9VIRU 5.97e-19 90.5 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_241161_1 2711.XP_006464459.1 8.72e-08 53.5 COG0484@1|root,KOG0712@2759|Eukaryota,37MSG@33090|Viridiplantae,3GGYH@35493|Streptophyta 35493|Streptophyta O DnaJ protein homolog - - - ko:K09503 ko04141,map04141 - - - ko00000,ko00001,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG k59_241161_2 1123487.KB892865_gene1394 7.96e-22 97.8 COG0749@1|root,COG0749@2|Bacteria,1MWX7@1224|Proteobacteria,2VMZW@28216|Betaproteobacteria 28216|Betaproteobacteria L DNA polymerase family A - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_257860_2 1379724.S5T6B0_9CIRC 3.78e-51 169.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_58681_1 742733.HMPREF9469_05062 5.47e-154 449.0 COG0553@1|root,COG0553@2|Bacteria,1TS9W@1239|Firmicutes,24CGX@186801|Clostridia,222GT@1506553|Lachnoclostridium 186801|Clostridia KL Helicase conserved C-terminal domain - - - - - - - - - - - - - k59_58681_7 525268.HMPREF0308_2070 1.49e-15 75.5 29XNQ@1|root,30JE6@2|Bacteria,2HZTS@201174|Actinobacteria,22PVB@1653|Corynebacteriaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_191277_1 439375.Oant_1547 2.36e-20 97.1 COG0464@1|root,COG0464@2|Bacteria 2|Bacteria O ATPase activity - - - ko:K06883 - - - - ko00000 - - - AAA,Mrr_cat k59_224631_1 2003327.CAPSD_BPCHP 2.13e-11 69.7 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_108453_2 1379724.S5T6B0_9CIRC 4.53e-19 92.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_83644_3 691965.D4P7C0_9CAUD 8.52e-55 175.0 4QDUR@10239|Viruses,4QVMY@35237|dsDNA viruses no RNA stage,4QU8R@28883|Caudovirales,4QKNQ@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_83644_4 478749.BRYFOR_08531 6.9e-17 77.4 2CGGA@1|root,345NF@2|Bacteria,1VZU0@1239|Firmicutes,253ZW@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_241263_1 1634476.A0A0F6TGK2_9CIRC 1.96e-26 110.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_191382_1 1234888.K0A2J2_9VIRU 1.31e-90 282.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_216548_2 485918.Cpin_3834 3.02e-26 103.0 COG0270@1|root,COG0270@2|Bacteria,4NRFG@976|Bacteroidetes,1IY5U@117747|Sphingobacteriia 976|Bacteroidetes L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_141872_3 1385658.U5KPZ6_9VIRU 4.72e-200 575.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_108588_2 585423.KR49_09340 3.32e-14 72.4 COG2227@1|root,COG2227@2|Bacteria 2|Bacteria H 3-demethylubiquinone-9 3-O-methyltransferase activity - - 2.1.1.222,2.1.1.64 ko:K00568 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04988,R05614,R08769,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31 k59_83650_1 71139.XP_010044350.1 6.26e-29 120.0 COG5108@1|root,KOG1038@2759|Eukaryota,37Q9S@33090|Viridiplantae,3G82K@35493|Streptophyta 35493|Streptophyta K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates - GO:0000428,GO:0000959,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006351,GO:0006390,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034245,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0098798,GO:0140053,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K10908 - - - - ko00000,ko01000,ko03029 - - - RNA_pol,RPOL_N k59_9114_1 1618251.A0A0C5I2L8_9CIRC 3.67e-45 164.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_118235_1 913183.E5RV19_9CAUD 4.03e-26 108.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QNI0@10744|Podoviridae 10744|Podoviridae S viral capsid - GO:0003674,GO:0005488,GO:0005515,GO:0042802 - - - - - - - - - - - k59_26960_2 748224.HMPREF9436_01152 2.37e-69 234.0 COG5511@1|root,COG5511@2|Bacteria,1TQ8B@1239|Firmicutes,24AAT@186801|Clostridia,3WGN0@541000|Ruminococcaceae 186801|Clostridia S Phage portal protein, lambda family - - - - - - - - - - - - Phage_portal_2 k59_126468_1 1125725.HMPREF1325_1310 6.09e-09 61.6 COG0863@1|root,COG0863@2|Bacteria 2|Bacteria L N-4 methylation of cytosine - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_225883_1 1123288.SOV_4c02780 2.02e-67 236.0 COG0503@1|root,COG0553@1|root,COG2263@1|root,COG3846@1|root,COG0503@2|Bacteria,COG0553@2|Bacteria,COG2263@2|Bacteria,COG3846@2|Bacteria,1TSYQ@1239|Firmicutes,4H5A6@909932|Negativicutes 909932|Negativicutes F protein secretion by the type IV secretion system - - - - - - - - - - - - SLT k59_84516_5 935261.JAGL01000009_gene1165 5.83e-58 199.0 COG0209@1|root,COG0209@2|Bacteria,1PM78@1224|Proteobacteria,2UZUM@28211|Alphaproteobacteria,43QGW@69277|Phyllobacteriaceae 28211|Alphaproteobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides - - - - - - - - - - - - - k59_259136_4 1472912.A0A023NG96_9CAUD 6.43e-26 97.4 4QDWQ@10239|Viruses,4QV9H@35237|dsDNA viruses no RNA stage,4QT88@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_159026_1 1385935.N836_35780 2.87e-60 200.0 28JU3@1|root,2Z9J6@2|Bacteria,1GFAJ@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - k59_208866_1 394.NGR_c11420 3.61e-05 52.0 COG1409@1|root,COG1409@2|Bacteria 2|Bacteria S acid phosphatase activity - - - - - - - - - - - - Big_5,Collagen,Peptidase_S74 k59_92997_2 1357279.N018_13055 1.1e-62 201.0 2E0AI@1|root,32VXW@2|Bacteria,1N2A1@1224|Proteobacteria,1SAFV@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_192172_3 105154.Q9MBU3_9VIRU 1.04e-17 84.3 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_192172_4 105154.Q9MBU6_9VIRU 1.85e-56 191.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_34997_2 2003327.CAPSD_BPCHP 1.23e-82 275.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_69368_2 1406785.U5PXQ1_9CAUD 1.87e-15 88.2 4QEE7@10239|Viruses,4QV59@35237|dsDNA viruses no RNA stage,4QPT7@28883|Caudovirales,4QI2X@10662|Myoviridae 10662|Myoviridae S Pfam:DUF4815 - - - - - - - - - - - - - k59_243311_10 766499.C357_05618 8.68e-32 119.0 COG3773@1|root,COG3773@2|Bacteria,1MWX3@1224|Proteobacteria,2TT15@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Cell wall hydrolyses involved in spore germination sleB - - - - - - - - - - - Hydrolase_2 k59_135939_1 948071.S4S2D9_9CAUD 4.67e-133 400.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QNQ6@10744|Podoviridae 10744|Podoviridae S ribonucleoside-triphosphate reductase activity - - - - - - - - - - - - - k59_202261_1 1234888.K0A2J2_9VIRU 1.63e-74 243.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_77983_2 1415147.V5Q7W6_9CAUD 1.71e-07 59.3 4QGP7@10239|Viruses,4R0IR@35237|dsDNA viruses no RNA stage,4QQ0Q@28883|Caudovirales,4QKUN@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_193448_1 1537917.JU82_00020 4.51e-28 107.0 COG0553@1|root,COG0553@2|Bacteria,1PM15@1224|Proteobacteria,42ZGS@68525|delta/epsilon subdivisions,2YS8B@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria L DEAD-like helicases superfamily - - - - - - - - - - - - - k59_243435_9 445970.ALIPUT_01194 9.38e-06 50.4 2E8S0@1|root,3332X@2|Bacteria,4NWIA@976|Bacteroidetes,2FUQI@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_85436_2 395493.BegalDRAFT_1453 3.84e-17 87.0 COG0582@1|root,COG0582@2|Bacteria,1MWBN@1224|Proteobacteria,1RPD0@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_integrase k59_128108_2 1692244.A0A0K1RLR5_9CIRC 7.33e-105 312.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_119715_1 1001530.BACE01000005_gene27 5.95e-09 56.2 COG1196@1|root,COG1196@2|Bacteria,1PPPK@1224|Proteobacteria,1TJ76@1236|Gammaproteobacteria,1Y0QY@135623|Vibrionales 135623|Vibrionales D nuclear chromosome segregation - - - - - - - - - - - - - k59_152954_1 1234888.K0A2J2_9VIRU 1.77e-24 102.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_12751_2 1046714.AMRX01000006_gene3195 1.1e-45 163.0 COG4626@1|root,COG4626@2|Bacteria 2|Bacteria S Terminase - - - - - - - - - - - - Terminase_1 k59_30169_2 445961.IW15_10100 2.3e-17 97.4 COG3941@1|root,COG3941@2|Bacteria,4NPQ5@976|Bacteroidetes 976|Bacteroidetes S tape measure - - - - - - - - - - - - - k59_137843_2 105154.Q9MBU6_9VIRU 2.19e-44 158.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_113284_3 1197906.CAJQ02000016_gene198 4.88e-15 88.2 28JTG@1|root,2Z9IR@2|Bacteria,1R0GC@1224|Proteobacteria,2TURR@28211|Alphaproteobacteria,3JUCC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF2793) - - - - - - - - - - - - DUF2793 k59_178985_3 66869.JNXG01000001_gene4057 2.32e-30 115.0 COG0270@1|root,COG0270@2|Bacteria,2GNB2@201174|Actinobacteria,41CRY@629295|Streptomyces griseus group 201174|Actinobacteria L DNA (cytosine-5-)-methyltransferase activity - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - - k59_71214_1 490913.C4NTD5_9CAUD 9.09e-43 158.0 4QGA5@10239|Viruses,4QURD@35237|dsDNA viruses no RNA stage,4QT9N@28883|Caudovirales,4QP47@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_154537_1 445971.ANASTE_00711 2e-08 59.3 COG1783@1|root,COG1783@2|Bacteria,1TRQP@1239|Firmicutes,248E9@186801|Clostridia,25YQA@186806|Eubacteriaceae 186801|Clostridia S Phage terminase, large subunit, PBSX family - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C k59_154537_3 856793.MICA_780 0.000134 52.0 COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,2TSXD@28211|Alphaproteobacteria,4BQKM@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria M Glycosyltransferase family 9 (heptosyltransferase) rfaF - - ko:K02843,ko:K02849 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 k59_46787_1 948071.S4S2T1_9CAUD 2e-107 336.0 4QHPY@10239|Viruses,4QWIA@35237|dsDNA viruses no RNA stage,4QSXS@28883|Caudovirales,4QNJ2@10744|Podoviridae 10744|Podoviridae S host cell wall - - - - - - - - - - - - - k59_95478_1 1795983.A0A140CTJ3_9CIRC 5.47e-29 118.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_129907_1 1347392.CCEZ01000043_gene417 3.14e-14 70.5 2E3AH@1|root,32YA0@2|Bacteria,1VGN7@1239|Firmicutes,25DV7@186801|Clostridia,36UF5@31979|Clostridiaceae 186801|Clostridia S Protein of unknown function (DUF1064) - - - - - - - - - - - - DUF1064 k59_46789_1 375286.mma_2211 6.59e-32 117.0 COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,2W3M1@28216|Betaproteobacteria,475QA@75682|Oxalobacteraceae 28216|Betaproteobacteria L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_46789_2 351016.RAZWK3B_16830 4.29e-34 124.0 COG1357@1|root,COG1357@2|Bacteria,1N7U9@1224|Proteobacteria,2UKXN@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Pentapeptide repeats (8 copies) - - - - - - - - - - - - Pentapeptide k59_154545_2 105154.Q9MBU6_9VIRU 3.5e-64 212.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_262092_1 2003327.CAPSD_BPCHP 1.51e-80 266.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_221694_1 756276.A0A096VKK9_9VIRU 3.86e-60 202.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage 10239|Viruses S Ribonucleotide reductase, barrel domain - GO:0001959,GO:0001960,GO:0003674,GO:0003824,GO:0004748,GO:0005575,GO:0008150,GO:0008152,GO:0009966,GO:0009968,GO:0010646,GO:0010648,GO:0010803,GO:0010804,GO:0016491,GO:0016725,GO:0016728,GO:0018995,GO:0023051,GO:0023057,GO:0030430,GO:0033643,GO:0033646,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0055114,GO:0060759,GO:0060761,GO:0061731,GO:0065007 - - - - - - - - - - - k59_20667_1 1266908.AQPB01000051_gene2466 4.19e-27 115.0 COG4653@1|root,COG4653@2|Bacteria,1MWMB@1224|Proteobacteria,1S4MJ@1236|Gammaproteobacteria,1X0RU@135613|Chromatiales 135613|Chromatiales S Phage capsid family - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_47021_1 1298867.AUES01000093_gene3157 1.26e-66 217.0 COG5545@1|root,COG5545@2|Bacteria,1MVGK@1224|Proteobacteria,2U0ID@28211|Alphaproteobacteria,3JWBU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Virulence-associated protein E - - - - - - - - - - - - Prim-Pol,Toprim_3,VirE k59_229120_1 1265503.KB905164_gene1928 8.64e-35 135.0 2DBV3@1|root,2ZB9F@2|Bacteria,1R7TT@1224|Proteobacteria,1RY7T@1236|Gammaproteobacteria,2Q7S2@267889|Colwelliaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_47022_1 1121101.HMPREF1532_03599 8.25e-20 87.0 COG1066@1|root,COG1066@2|Bacteria,4NN5C@976|Bacteroidetes,2FND9@200643|Bacteroidia,4AMI4@815|Bacteroidaceae 976|Bacteroidetes O ATP-dependent serine protease - - - - - - - - - - - - AAA k59_97010_1 749222.Nitsa_1177 3.64e-32 130.0 COG0507@1|root,COG0507@2|Bacteria,1R1AT@1224|Proteobacteria,42UU6@68525|delta/epsilon subdivisions,2YQ2G@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD - - - - - - - - - - - - - k59_97010_2 1094560.ME9_00022 3.05e-11 65.1 COG3170@1|root,COG3170@2|Bacteria,1R69E@1224|Proteobacteria,2U3B9@28211|Alphaproteobacteria,48TPA@772|Bartonellaceae 28211|Alphaproteobacteria NU Phage P22-like portal protein - - - - - - - - - - - - P22_portal k59_14369_2 1158150.KB906242_gene234 5.65e-81 248.0 2EMTV@1|root,33FG7@2|Bacteria 2|Bacteria S Gene 88 protein - - - - - - - - - - - - GP88 k59_237848_3 1168059.KB899087_gene1184 1.32e-22 94.4 COG3409@1|root,COG3409@2|Bacteria,1REI1@1224|Proteobacteria,2U734@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Putative peptidoglycan binding domain - - - - - - - - - - - - PG_binding_1 k59_88136_1 1525715.IX54_00205 1.32e-13 78.6 COG3941@1|root,COG5281@1|root,COG3941@2|Bacteria,COG5281@2|Bacteria,1PRTQ@1224|Proteobacteria,2TRVH@28211|Alphaproteobacteria,2PX64@265|Paracoccus 28211|Alphaproteobacteria S Lambda phage tail tape-measure protein (Tape_meas_lam_C) - - - - - - - - - - - - TMP_2,Tape_meas_lam_C k59_39313_2 742740.HMPREF9474_02265 3.3e-22 92.0 2CGG9@1|root,2ZVSJ@2|Bacteria,1V633@1239|Firmicutes,24HD0@186801|Clostridia,222RY@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_223894_1 1423724.BAMM01000010_gene1226 0.000952 48.9 COG1475@1|root,COG1475@2|Bacteria,1TP0I@1239|Firmicutes,4HAC6@91061|Bacilli,3F4RU@33958|Lactobacillaceae 91061|Bacilli K Belongs to the ParB family noc - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_189976_1 1211640.K4JUD3_9CAUD 1.35e-18 85.1 4QB08@10239|Viruses,4QY8E@35237|dsDNA viruses no RNA stage,4QRIV@28883|Caudovirales,4QM5X@10699|Siphoviridae 10699|Siphoviridae S exonuclease activity - - - - - - - - - - - - - k59_189976_4 202954.BBNK01000034_gene3794 1.31e-47 155.0 2A3Q7@1|root,30S7S@2|Bacteria,1NP2K@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_180934_1 439235.Dalk_3976 3.11e-08 56.6 COG4675@1|root,COG4675@2|Bacteria,1PFYN@1224|Proteobacteria,436DC@68525|delta/epsilon subdivisions,2X0YN@28221|Deltaproteobacteria,2MP2M@213118|Desulfobacterales 28221|Deltaproteobacteria S Phage Tail Collar Domain - - - - - - - - - - - - Collar k59_264048_1 1297570.MESS4_510151 8.55e-41 145.0 2EFF2@1|root,3397X@2|Bacteria,1P2XD@1224|Proteobacteria,2UYX3@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_173396_6 1986029.Q9MBM8_9VIRU 3.56e-78 262.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_214480_2 1233950.IW22_23360 1.35e-29 110.0 COG0847@1|root,COG0847@2|Bacteria,4NJMP@976|Bacteroidetes,1I0FQ@117743|Flavobacteriia,3ZP3X@59732|Chryseobacterium 976|Bacteroidetes L 3' exoribonuclease, RNase T-like - - - - - - - - - - - - DUF5051 k59_182144_2 1618248.A0A0C5IB82_9CIRC 3.56e-82 257.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_231950_1 428125.CLOLEP_01409 7.69e-164 474.0 COG4626@1|root,COG4626@2|Bacteria,1TT9I@1239|Firmicutes,24AFK@186801|Clostridia,3WNF4@541000|Ruminococcaceae 186801|Clostridia S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_247549_1 1379709.S5TMV0_9CIRC 2.83e-40 147.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_231953_1 391587.KAOT1_19572 0.000211 48.9 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,1HXMT@117743|Flavobacteriia 976|Bacteroidetes L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_15738_1 2003327.CAPSD_BPCHP 8.79e-16 79.7 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_182155_1 490913.C4NTA1_9CAUD 6.36e-48 167.0 4QAR1@10239|Viruses,4QUNA@35237|dsDNA viruses no RNA stage,4QPJE@28883|Caudovirales,4QNDS@10744|Podoviridae 10744|Podoviridae S ATPase activity - - - - - - - - - - - - - k59_214491_2 1385658.U5KPZ6_9VIRU 1.9e-133 397.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_165366_1 1166018.FAES_3259 2.86e-51 171.0 2BYEQ@1|root,32SXE@2|Bacteria,4P5T1@976|Bacteroidetes,47VNQ@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_165366_2 697281.Mahau_2914 6.31e-15 75.9 COG4695@1|root,COG4695@2|Bacteria,1TP8B@1239|Firmicutes,2497C@186801|Clostridia,42FVH@68295|Thermoanaerobacterales 186801|Clostridia S TIGRFAM phage portal protein, HK97 family - - - - - - - - - - - - Phage_Mu_F,Phage_portal k59_239560_2 665571.STHERM_c17410 2e-15 75.1 COG4696@1|root,COG4696@2|Bacteria 2|Bacteria J Protein conserved in bacteria XK27_03185 - - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - Acetyltransf_3,Hydrolase_3,PRA-PH k59_249139_1 691965.D4P7E6_9CAUD 3.96e-77 261.0 4QAK6@10239|Viruses,4R01K@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_91526_1 2003327.CAPSD_BPCHP 2.15e-30 125.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_199309_9 344747.PM8797T_14906 1.41e-89 280.0 COG2165@1|root,COG2165@2|Bacteria,2IXWM@203682|Planctomycetes 203682|Planctomycetes NU Pfam:N_methyl_2 - - - - - - - - - - - - N_methyl,SBP_bac_10 k59_66615_1 1219035.NT2_13_00580 5.18e-27 113.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_116455_1 698761.RTCIAT899_CH12160 7.91e-14 82.8 COG4409@1|root,COG4409@2|Bacteria,1PGPV@1224|Proteobacteria,2V361@28211|Alphaproteobacteria,4BK71@82115|Rhizobiaceae 28211|Alphaproteobacteria G exo-alpha-(2->6)-sialidase activity - - - - - - - - - - - - - k59_116490_13 903818.KI912269_gene35 7.22e-10 67.0 COG0823@1|root,COG4676@1|root,COG0823@2|Bacteria,COG4676@2|Bacteria 2|Bacteria UW Protein conserved in bacteria - - - - - - - - - - - - DUF3253,UPF0560 k59_157889_2 32057.KB217478_gene2057 4.95e-29 112.0 2DR0J@1|root,32UQ6@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_59269_2 1007105.PT7_P059 4.52e-42 155.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2VNHP@28216|Betaproteobacteria,3T3DM@506|Alcaligenaceae 28216|Betaproteobacteria S COG4626 Phage terminase-like protein, large subunit - - - - - - - - - - - - Terminase_1 k59_26427_1 1234888.K0A2J2_9VIRU 1.18e-124 375.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_249993_1 111781.Lepto7376_3582 2.02e-07 56.6 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1G1P1@1117|Cyanobacteria,1H8EM@1150|Oscillatoriales 1117|Cyanobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_200248_2 710696.Intca_0489 6.2e-13 72.8 COG1404@1|root,COG1404@2|Bacteria,2GJYH@201174|Actinobacteria,4FIKZ@85021|Intrasporangiaceae 201174|Actinobacteria M Peptidase inhibitor I9 - - - - - - - - - - - - Inhibitor_I9,PKD,Peptidase_S8 k59_225265_6 742727.HMPREF9447_04874 4.4e-44 154.0 COG0863@1|root,COG0863@2|Bacteria,4NQQ1@976|Bacteroidetes,2G1PS@200643|Bacteroidia,4ARBB@815|Bacteroidaceae 976|Bacteroidetes L DNA methylase - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_225265_7 279808.SH1757 0.00011 48.1 COG3440@1|root,COG3440@2|Bacteria,1V6VD@1239|Firmicutes,4HUXV@91061|Bacilli 91061|Bacilli V Restriction endonuclease - - - - - - - - - - - - DUF2726 k59_225265_8 1150621.SMUL_1732 1.48e-13 75.9 29X4D@1|root,30IT8@2|Bacteria,1Q30S@1224|Proteobacteria,42WJT@68525|delta/epsilon subdivisions,2YQ6Y@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria S Domain of unknown function (DUF4373) - - - - - - - - - - - - DUF4373 k59_249994_1 351746.Pput_4115 7.73e-56 194.0 COG3740@1|root,COG3740@2|Bacteria,1QVIJ@1224|Proteobacteria,1T44Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Caudovirus prohead serine protease - - - ko:K06904 - - - - ko00000 - - - Peptidase_S78,Phage_capsid k59_117525_2 1307759.JOMJ01000003_gene1802 3.64e-19 88.6 COG5565@1|root,COG5565@2|Bacteria,1R6R3@1224|Proteobacteria,43BCR@68525|delta/epsilon subdivisions,2X6RN@28221|Deltaproteobacteria,2MA58@213115|Desulfovibrionales 28221|Deltaproteobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C k59_175173_2 272134.KB731324_gene2191 3.89e-06 56.2 2A680@1|root,30V0J@2|Bacteria,1GFCR@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - k59_175173_3 596153.Alide_2077 5.25e-119 356.0 COG4373@1|root,COG4373@2|Bacteria,1N2KG@1224|Proteobacteria,2VNJ9@28216|Betaproteobacteria,4ACTG@80864|Comamonadaceae 28216|Betaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_183623_1 1463887.KL589968_gene7425 9.18e-07 50.8 2AU1G@1|root,31JMM@2|Bacteria,2IJKK@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_9412_3 1100720.ALKN01000018_gene1738 2.93e-120 370.0 COG1061@1|root,COG1061@2|Bacteria,1MV9F@1224|Proteobacteria,2VQF3@28216|Betaproteobacteria,4ADUP@80864|Comamonadaceae 28216|Betaproteobacteria L Helicase conserved C-terminal domain - - - - - - - - - - - - Helicase_C,ResIII,UPF0547 k59_9412_9 459349.CLOAM0215 6.35e-26 102.0 COG3772@1|root,COG3772@2|Bacteria 2|Bacteria S cytolysis by virus of host cell - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_9412_11 1121948.AUAC01000007_gene413 3.79e-16 88.2 COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,2TS2G@28211|Alphaproteobacteria,43X4X@69657|Hyphomonadaceae 28211|Alphaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_3,Phage_integrase k59_9412_15 1121396.KB893112_gene2006 5.52e-44 149.0 COG2110@1|root,COG2110@2|Bacteria,1R2H8@1224|Proteobacteria,42SEQ@68525|delta/epsilon subdivisions,2WPTN@28221|Deltaproteobacteria,2MK9R@213118|Desulfobacterales 28221|Deltaproteobacteria S Macro domain - - - - - - - - - - - - Macro k59_9412_16 1168034.FH5T_14940 1.44e-17 79.3 COG1525@1|root,COG1525@2|Bacteria,4NR4U@976|Bacteroidetes 976|Bacteroidetes L Staphylococcal nuclease homologue - - 3.1.31.1 ko:K01174 - - - - ko00000,ko01000 - - - SNase k59_9412_17 1117314.PCIT_14766 1.36e-09 58.2 2E645@1|root,330T3@2|Bacteria,1NEGX@1224|Proteobacteria,1SC3K@1236|Gammaproteobacteria,2Q4P5@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S Holin of 3TMs, for gene-transfer release - - - - - - - - - - - - GTA_holin_3TM k59_258713_5 202952.BBLI01000124_gene3974 1.5e-69 230.0 COG3843@1|root,COG3843@2|Bacteria,1QW4J@1224|Proteobacteria,1T2SH@1236|Gammaproteobacteria,3NM42@468|Moraxellaceae 1236|Gammaproteobacteria U MobA/MobL family - - - - - - - - - - - - MobA_MobL k59_217304_1 876269.ARWA01000001_gene993 5.26e-26 109.0 COG1216@1|root,COG1216@2|Bacteria,1R554@1224|Proteobacteria,2U3P6@28211|Alphaproteobacteria,3N9XF@45404|Beijerinckiaceae 28211|Alphaproteobacteria S Glycosyl transferase, family 2 MA20_08330 - - - - - - - - - - - Glyco_tranf_2_3 k59_184586_2 69279.BG36_20870 4.7e-197 578.0 COG3170@1|root,COG3170@2|Bacteria,1QVEE@1224|Proteobacteria,2TWDG@28211|Alphaproteobacteria 28211|Alphaproteobacteria NU Phage P22-like portal protein - - - - - - - - - - - - P22_portal k59_151882_3 268748.Q58N42_BPPRP 2.33e-23 102.0 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales,4QNBW@10744|Podoviridae 10744|Podoviridae S DNA helicase activity - - - - - - - - - - - - - k59_84765_1 1345023.M467_10610 1.69e-58 196.0 COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,4H9U5@91061|Bacilli,3WFED@539002|Bacillales incertae sedis 91061|Bacilli M GDP-mannose 4,6 dehydratase galE - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd k59_192570_1 1165094.RINTHH_3920 6.85e-75 239.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_192570_3 105154.Q9MBU6_9VIRU 1.18e-187 542.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_234047_2 1692244.A0A0K1RLR5_9CIRC 3.95e-28 114.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_77195_2 1268072.PSAB_20425 6.72e-05 53.9 COG0726@1|root,COG0726@2|Bacteria 2|Bacteria G polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 k59_152006_1 1379708.S5SYC3_9CIRC 5.06e-16 82.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_192695_1 1321778.HMPREF1982_02859 6.55e-15 79.7 COG0749@1|root,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia,267MY@186813|unclassified Clostridiales 186801|Clostridia L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity - - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - DNA_pol_A,DNA_pol_A_exo1 k59_119103_1 489825.LYNGBM3L_53020 1.03e-06 56.6 COG1216@1|root,COG1216@2|Bacteria,1GCKG@1117|Cyanobacteria 1117|Cyanobacteria S Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 k59_77206_1 1094561.MEI_00978 4.63e-09 58.9 COG4675@1|root,COG4675@2|Bacteria,1N0FZ@1224|Proteobacteria,2UDXB@28211|Alphaproteobacteria,48T3C@772|Bartonellaceae 28211|Alphaproteobacteria S Phage Tail Collar Domain - - - - - - - - - - - - Collar k59_68710_1 314345.SPV1_06324 1.67e-81 268.0 COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria 1224|Proteobacteria L Subunit R is required for both nuclease and ATPase activities, but not for modification - - 3.1.21.3 ko:K01153 - - - - ko00000,ko01000,ko02048 - - - DUF3387,HSDR_N,ResIII k59_143823_3 760154.Sulba_2171 3.93e-06 54.3 COG3593@1|root,COG3593@2|Bacteria,1NN6Q@1224|Proteobacteria,43DB2@68525|delta/epsilon subdivisions 1224|Proteobacteria L AAA ATPase domain - - - - - - - - - - - - AAA_15 k59_43965_1 105154.Q9MBU3_9VIRU 1.06e-05 52.4 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_52416_1 1379712.S5TMV9_9CIRC 1.98e-17 87.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_250836_1 1692249.A0A0K1RLN8_9CIRC 1.25e-16 80.1 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_110339_1 349519.LCK_01046 0.000253 53.9 COG0791@1|root,COG2268@1|root,COG3953@1|root,COG5283@1|root,COG0791@2|Bacteria,COG2268@2|Bacteria,COG3953@2|Bacteria,COG5283@2|Bacteria,1UZN8@1239|Firmicutes,4HBX8@91061|Bacilli,4AWYE@81850|Leuconostocaceae 91061|Bacilli M by MetaGeneAnnotator - - - - - - - - - - - - NLPC_P60,PhageMin_Tail,SLT k59_184748_1 794903.OPIT5_03855 2.4e-35 139.0 COG5511@1|root,COG5511@2|Bacteria 2|Bacteria F Phage portal protein, lambda family - - - - - - - - - - - - Phage_portal_2 k59_209325_1 292414.TM1040_0821 2.63e-12 71.6 COG3391@1|root,COG3391@2|Bacteria 2|Bacteria CO amine dehydrogenase activity - - - ko:K12287 - - - - ko00000,ko02044 - - - DUF11,VCBS k59_209325_2 666684.AfiDRAFT_3723 2.23e-23 109.0 COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,2TS2G@28211|Alphaproteobacteria,3JWPH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_3,Phage_integrase k59_209325_4 323259.Mhun_0724 6.77e-32 122.0 arCOG07591@1|root,arCOG07591@2157|Archaea,2XX06@28890|Euryarchaeota 28890|Euryarchaeota S von Willebrand factor (vWF) type A domain - - - - - - - - - - - - VWA,VWA_2 k59_234975_1 1463825.JNXC01000023_gene4886 5.44e-28 112.0 2EGUB@1|root,33AKH@2|Bacteria,2I97J@201174|Actinobacteria,4E4PE@85010|Pseudonocardiales 201174|Actinobacteria - - - - - - - - - - - - - - - k59_145171_1 1692252.A0A0K1RL35_9CIRC 1.88e-43 152.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_94322_1 1370120.AUWR01000092_gene2064 5.54e-05 52.4 2EP1Y@1|root,33GNT@2|Bacteria,2IC2I@201174|Actinobacteria,2380S@1762|Mycobacteriaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_136347_2 665950.HMPREF1025_01994 1.46e-60 201.0 28J3N@1|root,2Z8ZU@2|Bacteria,1V15Z@1239|Firmicutes,249Z0@186801|Clostridia 186801|Clostridia S Phage portal protein - - - - - - - - - - - - Phage_portal k59_202548_2 742740.HMPREF9474_02303 6.92e-41 153.0 2EWZQ@1|root,33QB0@2|Bacteria,1V0T1@1239|Firmicutes,249Z2@186801|Clostridia,221YV@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_28819_2 113395.AXAI01000008_gene735 3.34e-09 62.0 COG1403@1|root,COG1403@2|Bacteria,1N0FM@1224|Proteobacteria,2TWQN@28211|Alphaproteobacteria 28211|Alphaproteobacteria V ERF superfamily - - - - - - - - - - - - ERF k59_160799_1 1084719.G3MBS1_9CAUD 6.14e-27 114.0 4QCN3@10239|Viruses,4R03K@35237|dsDNA viruses no RNA stage,4QR5D@28883|Caudovirales,4QI2B@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_185909_1 1618247.A0A0C5IMK7_9CIRC 5.7e-09 60.5 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_193819_1 1517681.HW45_28655 5.66e-39 143.0 COG3969@1|root,COG3969@2|Bacteria,1NBDM@1224|Proteobacteria,1RYRP@1236|Gammaproteobacteria,1XT86@135623|Vibrionales 135623|Vibrionales S Domain of unknown function (DUF3440) - - - - - - - - - - - - DUF3440,PAPS_reduct k59_193819_3 1399774.JDWH01000007_gene1634 7.01e-33 118.0 COG1475@1|root,COG1475@2|Bacteria,1R5VN@1224|Proteobacteria,1RZ7C@1236|Gammaproteobacteria 1236|Gammaproteobacteria K ParB-like nuclease domain ybdM - - - - - - - - - - - ParBc k59_103005_1 444875.E3SMF7_9CAUD 1.71e-06 55.8 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QNBD@10744|Podoviridae 10744|Podoviridae S outer membrane - - - - - - - - - - - - - k59_227679_2 1300005.R9RGD4_9CAUD 6.52e-22 92.0 4QB2U@10239|Viruses,4QVJC@35237|dsDNA viruses no RNA stage,4QTMH@28883|Caudovirales 28883|Caudovirales S Pfam:GTA_holin_3TM - - - - - - - - - - - - - k59_186067_2 1048339.KB913029_gene3504 6.38e-68 228.0 COG0004@1|root,COG0004@2|Bacteria,2GIZK@201174|Actinobacteria,4ERCB@85013|Frankiales 201174|Actinobacteria P Ammonium Transporter amtB - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp k59_186067_4 1115632.JAFW01000001_gene3445 1.34e-25 106.0 arCOG05626@1|root,2Z9D9@2|Bacteria,2IIAB@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_128629_1 82654.Pse7367_3936 1.14e-32 133.0 COG4383@1|root,COG4383@2|Bacteria 2|Bacteria L Mu-like prophage protein gp29 - - - - - - - - - - - - DUF935 k59_95485_5 487521.OCU_06970 8.83e-46 174.0 2EP1Y@1|root,33GNT@2|Bacteria,2IC2I@201174|Actinobacteria,2380S@1762|Mycobacteriaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_236323_2 1117318.PRUB_23551 2.32e-07 55.1 COG0535@1|root,COG0535@2|Bacteria,1PEN5@1224|Proteobacteria,1SDT2@1236|Gammaproteobacteria,2Q3ED@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria C Iron-sulfur cluster-binding domain - - - - - - - - - - - - Radical_SAM,SPASM k59_187582_1 10719.Q9T217_BPPHC 8.79e-17 83.2 4QAY9@10239|Viruses,4QV7W@35237|dsDNA viruses no RNA stage,4QPAN@28883|Caudovirales,4QKV1@10699|Siphoviridae 10699|Siphoviridae S hydrolase activity - - - - - - - - - - - - - k59_204263_2 1217715.F994_02776 8.18e-12 65.1 2DYV8@1|root,32V63@2|Bacteria,1QNWV@1224|Proteobacteria,1ST2X@1236|Gammaproteobacteria,3NNP1@468|Moraxellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_262252_2 1609634.A0A0C5AFV4_9VIRU 5.47e-77 246.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_55062_1 1157708.KB907450_gene5441 2.13e-07 62.0 COG5434@1|root,COG5434@2|Bacteria,1RCW1@1224|Proteobacteria,2W4G2@28216|Betaproteobacteria 28216|Betaproteobacteria M Pectate lyase superfamily protein - - - - - - - - - - - - Pectate_lyase_3 k59_20789_1 1112217.PPL19_12403 6.81e-44 172.0 COG3451@1|root,COG3451@2|Bacteria,1MUEN@1224|Proteobacteria,1RPAY@1236|Gammaproteobacteria 1236|Gammaproteobacteria U type IV secretory pathway, VirB4 components - - - - - - - - - - - - DUF87,TraC_F_IV k59_179131_1 398767.Glov_1679 8.33e-25 100.0 COG3740@1|root,COG3740@2|Bacteria,1NHKT@1224|Proteobacteria,433JC@68525|delta/epsilon subdivisions,2WYCB@28221|Deltaproteobacteria 28221|Deltaproteobacteria S PFAM Peptidase U35, phage prohead HK97 - - - ko:K06904 - - - - ko00000 - - - Peptidase_S78 k59_179131_2 1286171.EAL2_c11040 3.51e-16 82.4 COG4695@1|root,COG4695@2|Bacteria,1TP8B@1239|Firmicutes,2497C@186801|Clostridia,25VW6@186806|Eubacteriaceae 186801|Clostridia S Phage portal protein - - - - - - - - - - - - Phage_portal k59_171358_2 105154.Q9MBU0_9VIRU 9.16e-08 53.9 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_221857_1 563192.HMPREF0179_03464 2.73e-48 184.0 COG5108@1|root,COG5108@2|Bacteria,1PIWB@1224|Proteobacteria,42YXG@68525|delta/epsilon subdivisions,2WU1V@28221|Deltaproteobacteria,2M9ED@213115|Desulfovibrionales 28221|Deltaproteobacteria K DNA-dependent RNA polymerase - - - - - - - - - - - - RNA_pol,RPOL_N k59_138017_1 580331.Thit_0485 2.9e-42 152.0 COG0338@1|root,COG0338@2|Bacteria,1TRDX@1239|Firmicutes,25E75@186801|Clostridia,42G63@68295|Thermoanaerobacterales 186801|Clostridia H PFAM D12 class N6 adenine-specific DNA methyltransferase dam - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 k59_162269_1 50948.Q76XG6_9CAUD 2.84e-30 124.0 4QAUT@10239|Viruses,4QVIM@35237|dsDNA viruses no RNA stage,4QQ7X@28883|Caudovirales,4QIGV@10662|Myoviridae 10662|Myoviridae S DNA ligase (ATP) activity - - - - - - - - - - - - - k59_30392_1 1440052.EAKF1_ch1474c 3.21e-29 116.0 COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,1RNE0@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_3,Phage_int_SAM_3,Phage_integrase k59_262258_2 562982.HMPREF0432_01569 3.69e-05 51.2 COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,4H9MW@91061|Bacilli,3WE8F@539002|Bacillales incertae sedis 91061|Bacilli L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N k59_55068_1 1439940.BAY1663_02340 3.18e-96 303.0 COG3740@1|root,COG3740@2|Bacteria,1QVIJ@1224|Proteobacteria,1T44Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Caudovirus prohead serine protease - - - ko:K06904 - - - - ko00000 - - - Peptidase_S78,Phage_capsid k59_37688_2 196490.AUEZ01000004_gene3907 2.6e-63 201.0 2DMWU@1|root,32U5P@2|Bacteria,1RAAA@1224|Proteobacteria,2U5E1@28211|Alphaproteobacteria,3K51A@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S DNA N-6-adenine-methyltransferase (Dam) - - - - - - - - - - - - Dam k59_37688_3 399741.Spro_4945 4.97e-24 95.5 2E3AH@1|root,32YA0@2|Bacteria,1NBUZ@1224|Proteobacteria 1224|Proteobacteria S Protein of unknown function (DUF1064) - - - - - - - - - - - - DUF1064 k59_244803_2 1217710.F969_02564 3.24e-55 189.0 2CHRY@1|root,30Z9E@2|Bacteria,1RGQK@1224|Proteobacteria,1T1AM@1236|Gammaproteobacteria,3NKV5@468|Moraxellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - RecT k59_244803_3 1280706.AUJE01000017_gene127 1.11e-06 48.5 COG1396@1|root,COG1396@2|Bacteria 2|Bacteria K sequence-specific DNA binding - - - - - - - - - - - - HTH_19,HTH_3 k59_221865_1 1141137.K4F9S4_9CAUD 4.96e-15 81.6 4QHDC@10239|Viruses,4QVYW@35237|dsDNA viruses no RNA stage,4QRRQ@28883|Caudovirales,4QNTD@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_62300_1 742823.HMPREF9465_01261 1.36e-21 99.4 COG0749@1|root,COG0749@2|Bacteria,1MWX7@1224|Proteobacteria,2VMZW@28216|Betaproteobacteria 28216|Betaproteobacteria L DNA polymerase family A - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_79513_2 1118153.MOY_16467 2.17e-76 251.0 28IN7@1|root,2Z8NM@2|Bacteria 2|Bacteria S Capsid protein (F protein) - - - - - - - - - - - - Phage_F k59_254255_1 931627.MycrhDRAFT_3467 0.000292 46.2 COG4677@1|root,COG4677@2|Bacteria 2|Bacteria G pectinesterase activity - - - - - - - - - - - - Beta_helix,Lipase_GDSL_2,NosD,Pectate_lyase_3 k59_13999_2 1121440.AUMA01000002_gene2130 2.55e-06 56.2 COG2227@1|root,COG2227@2|Bacteria,1PFWQ@1224|Proteobacteria,43231@68525|delta/epsilon subdivisions 1224|Proteobacteria H Methionine biosynthesis protein MetW - - - - - - - - - - - - Methyltransf_23 k59_263550_2 240016.ABIZ01000001_gene5053 9.99e-10 58.9 2DR7Z@1|root,33AM6@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_96737_1 762982.HMPREF9442_01215 1.25e-05 50.4 2F39H@1|root,33W3U@2|Bacteria,4P376@976|Bacteroidetes,2FTPI@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_254268_1 743721.Psesu_1163 8.08e-35 130.0 COG1783@1|root,COG1783@2|Bacteria,1R66A@1224|Proteobacteria,1RQFD@1236|Gammaproteobacteria,1XC4F@135614|Xanthomonadales 135614|Xanthomonadales S Phage terminase large subunit - - - ko:K06909 - - - - ko00000 - - - Terminase_3 k59_148428_1 1205681.CALW02000096_gene1171 9.75e-43 147.0 COG3170@1|root,COG3170@2|Bacteria,1R69E@1224|Proteobacteria,2U3B9@28211|Alphaproteobacteria,48T9Q@772|Bartonellaceae 28211|Alphaproteobacteria NU Phage P22-like portal protein - - - - - - - - - - - - P22_portal k59_205714_1 1161935.H9D1E7_9CAUD 9.34e-45 164.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_72841_1 438753.AZC_3598 1.66e-166 485.0 COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1QT52@1224|Proteobacteria,2TVNI@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Toprim-like - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - DnaB_C,Toprim_2 k59_22218_1 1468179.A0A0C4K5Y2_9VIRU 8.52e-09 61.6 4QAK6@10239|Viruses 10239|Viruses S N-acetylmuramoyl-L-alanine amidase activity - - - - - - - - - - - - - k59_205837_1 438753.AZC_3597 3.77e-218 623.0 COG0749@1|root,COG0749@2|Bacteria,1P27P@1224|Proteobacteria,2TVEI@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DNA polymerase family A - - - - - - - - - - - - DNA_pol_A k59_96835_1 1379710.S5TNC2_9CIRC 1.1e-24 106.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_172968_1 440250.A5HL30_9CAUD 3.65e-62 210.0 4QGAG@10239|Viruses,4R0KB@35237|dsDNA viruses no RNA stage,4QUA4@28883|Caudovirales,4QNFP@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_87936_1 1429916.X566_20010 7.27e-44 148.0 COG1917@1|root,COG1917@2|Bacteria,1N6Q0@1224|Proteobacteria,2UKI2@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Cupin 2, conserved barrel domain protein - - - - - - - - - - - - - k59_87936_2 1166948.JPZL01000002_gene1629 7.72e-19 85.1 2DRN8@1|root,33CCM@2|Bacteria,1NGRN@1224|Proteobacteria 1224|Proteobacteria - - - - 3.4.25.2 ko:K01419 - - - - ko00000,ko01000,ko01002 - - - - k59_230367_1 674977.VMC_02920 1.52e-07 54.7 COG0749@1|root,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria 1236|Gammaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity - - - - - - - - - - - - DNA_pol_A k59_181795_2 1268622.AVS7_01538 1.78e-84 255.0 COG1961@1|root,COG1961@2|Bacteria,1MXXT@1224|Proteobacteria,2VJ32@28216|Betaproteobacteria,4AHQF@80864|Comamonadaceae 28216|Betaproteobacteria L Resolvase, N terminal domain tniR - - - - - - - - - - - Resolvase k59_197829_1 326297.Sama_1727 1.72e-78 244.0 COG0208@1|root,COG0208@2|Bacteria,1MWUS@1224|Proteobacteria,1RMJC@1236|Gammaproteobacteria,2Q944@267890|Shewanellaceae 1236|Gammaproteobacteria C PFAM ribonucleotide reductase nrdB GO:0003674,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0015949,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - iAPECO1_1312.APECO1_4325 Ribonuc_red_sm k59_197829_2 1515746.HR45_02850 2.26e-08 55.8 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,1RMPV@1236|Gammaproteobacteria,2Q9ZW@267890|Shewanellaceae 1236|Gammaproteobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdA GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0015949,GO:0016491,GO:0016725,GO:0016728,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - iSDY_1059.SDY_2428 ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN k59_247192_2 1123508.JH636464_gene276 1.83e-25 110.0 COG1061@1|root,COG1061@2|Bacteria,2J0ES@203682|Planctomycetes 203682|Planctomycetes L COGs COG1061 DNA or RNA helicase of superfamily II - - - ko:K19789 - - - - ko00000,ko03400 - - - Helicase_C,ResIII k59_97959_2 339860.Msp_1550 9.73e-94 300.0 COG0464@1|root,arCOG01308@2157|Archaea,2Y2E2@28890|Euryarchaeota,23PGB@183925|Methanobacteria 183925|Methanobacteria O ATPase family associated with various cellular activities (AAA) - - - - - - - - - - - - AAA k59_40259_1 1380347.JNII01000006_gene1446 2.33e-66 250.0 COG1749@1|root,COG2372@1|root,COG5184@1|root,COG1749@2|Bacteria,COG2372@2|Bacteria,COG5184@2|Bacteria,2I2X3@201174|Actinobacteria,4EUDH@85013|Frankiales 201174|Actinobacteria N Bacterial Ig-like domain - - - - - - - - - - - - Big_5,DUF4082,Mo-co_dimer,fn3 k59_15336_2 1788438.A0A190WHE1_9CIRC 0.000124 50.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_157343_2 1465639.A0A060BL22_9CAUD 8.35e-07 55.1 4QBAU@10239|Viruses,4QW8E@35237|dsDNA viruses no RNA stage,4QPEP@28883|Caudovirales,4QNY1@10744|Podoviridae 10744|Podoviridae S viral capsid assembly - - - - - - - - - - - - - k59_74223_1 204773.HEAR2295 9.01e-102 300.0 COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,2W3M1@28216|Betaproteobacteria,475QA@75682|Oxalobacteraceae 28216|Betaproteobacteria L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_264897_11 1245475.ANAE01000096_gene4235 6.86e-07 52.0 2DN02@1|root,32UNW@2|Bacteria,2IGV8@201174|Actinobacteria 201174|Actinobacteria S Protein of unknown function (DUF3887) - - - - - - - - - - - - DUF3887 k59_83132_5 573.JG24_07830 1.19e-13 77.4 COG3497@1|root,COG3497@2|Bacteria,1MW1V@1224|Proteobacteria,1RNUT@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Tail sheath protein fI - - ko:K06907 - - - - ko00000 - - - Phage_sheath_1,Phage_sheath_1C k59_108048_4 1445859.W6E9J9_9CAUD 4.97e-26 100.0 4QB6G@10239|Viruses,4QVYX@35237|dsDNA viruses no RNA stage,4QQS8@28883|Caudovirales 28883|Caudovirales S Peptidase M15 - - - - - - - - - - - - - k59_199202_2 47839.CCAU010000021_gene3123 1.78e-16 79.0 COG0343@1|root,COG0343@2|Bacteria,2I9KU@201174|Actinobacteria,238ZT@1762|Mycobacteriaceae 201174|Actinobacteria J queuine tRNA-ribosyltransferase activity - - - - - - - - - - - - - k59_91410_1 1234888.K0A2J2_9VIRU 8.44e-50 174.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_91410_2 1234888.K0A2R8_9VIRU 4.67e-55 186.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_224089_15 504472.Slin_4835 9e-25 101.0 COG1961@1|root,COG1961@2|Bacteria,4NNF6@976|Bacteroidetes,47Q4K@768503|Cytophagia 976|Bacteroidetes L Resolvase, N terminal domain - - - - - - - - - - - - HTH_7,Resolvase k59_224089_16 1120956.JHZK01000013_gene2542 4.38e-16 75.9 2CDFK@1|root,2Z8BH@2|Bacteria,1QZFS@1224|Proteobacteria 1224|Proteobacteria S DNA N-6-adenine-methyltransferase (Dam) - - - - - - - - - - - - Dam k59_190966_3 1205683.CAKR01000025_gene3612 7.46e-11 64.3 2BU68@1|root,32PFD@2|Bacteria,1N2SX@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_100563_3 1217656.F964_00563 1.33e-57 190.0 COG0863@1|root,COG0863@2|Bacteria,1QN45@1224|Proteobacteria,1S1V3@1236|Gammaproteobacteria,3NSV6@468|Moraxellaceae 1236|Gammaproteobacteria L DNA methylase - - - - - - - - - - - - N6_N4_Mtase k59_150413_2 1305732.JAGG01000001_gene1901 7.1e-29 115.0 COG0463@1|root,COG0463@2|Bacteria,2IB0Y@201174|Actinobacteria,4FNC2@85023|Microbacteriaceae 201174|Actinobacteria M Glycosyl transferase family 2 - - - - - - - - - - - - Glyco_tranf_2_4 k59_100668_1 156889.Mmc1_1012 2.25e-05 52.4 COG2268@1|root,COG2268@2|Bacteria,1NT13@1224|Proteobacteria,2U335@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Band 7 protein - - - - - - - - - - - - - k59_83978_1 1123279.ATUS01000005_gene3105 2.82e-54 177.0 2DNB5@1|root,32WIW@2|Bacteria,1N0BM@1224|Proteobacteria,1S8UT@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Bacteriophage HK97-gp10, putative tail-component - - - - - - - - - - - - HK97-gp10_like k59_258484_1 945713.IALB_0072 6.58e-17 86.3 2FF1D@1|root,346ZT@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_217047_2 632518.Calow_0833 4.52e-09 64.7 28JC4@1|root,2Z96S@2|Bacteria,1TS1K@1239|Firmicutes,249Q6@186801|Clostridia 186801|Clostridia S P22 coat protein-protein 5 domain protein - - - - - - - - - - - - P22_CoatProtein k59_108958_3 145579.REP_BPPHM 4.04e-11 70.5 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_249879_1 948071.S4S2D9_9CAUD 3.68e-187 544.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QNQ6@10744|Podoviridae 10744|Podoviridae S ribonucleoside-triphosphate reductase activity - - - - - - - - - - - - - k59_233213_1 1110502.TMO_2323 1.09e-74 239.0 COG5492@1|root,COG5492@2|Bacteria,1MX1X@1224|Proteobacteria,2VG4Y@28211|Alphaproteobacteria 28211|Alphaproteobacteria N domain, Protein - - - - - - - - - - - - - k59_191688_1 1041142.ATTP01000043_gene5299 0.000246 47.4 2DTAB@1|root,33JEU@2|Bacteria,1NNYR@1224|Proteobacteria,2UKBA@28211|Alphaproteobacteria,4BG36@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_26262_1 1220601.L7TQY6_9CAUD 5.25e-31 119.0 4QBMX@10239|Viruses,4QV9I@35237|dsDNA viruses no RNA stage,4QQGF@28883|Caudovirales 28883|Caudovirales S Pfam:Tube - GO:0005575,GO:0019012 - - - - - - - - - - - k59_42705_1 1692242.A0A0K1RKZ2_9CIRC 1.28e-14 75.1 4QFEW@10239|Viruses,4QUKZ@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_42705_2 1692257.A0A0K1RL39_9CIRC 5.75e-10 60.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_258491_1 1274524.BSONL12_06038 2.36e-41 159.0 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,4H9Z7@91061|Bacilli,1ZEKP@1386|Bacillus 91061|Bacilli L DNA polymerase A domain - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_225159_1 1163617.SCD_n01069 4.02e-34 134.0 COG3378@1|root,COG3378@2|Bacteria,1QVIS@1224|Proteobacteria,2VPDW@28216|Betaproteobacteria 28216|Betaproteobacteria S Phage plasmid primase, P4 family domain protein - - - ko:K06919 - - - - ko00000 - - - - k59_241577_1 1415146.V5Q8Q5_9CAUD 3.24e-65 228.0 4QBMV@10239|Viruses,4QUU6@35237|dsDNA viruses no RNA stage,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_1438_9 1471542.A0A023ZWF6_9CAUD 3.12e-13 74.7 4QM6C@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_27287_2 1096546.WYO_0174 4.04e-65 241.0 COG1467@1|root,COG5519@1|root,COG1467@2|Bacteria,COG5519@2|Bacteria,1QTGG@1224|Proteobacteria,2V9QI@28211|Alphaproteobacteria,1JY2B@119045|Methylobacteriaceae 28211|Alphaproteobacteria L DNA primase - - - - - - - - - - - - - k59_126797_1 991.IW20_20125 3.69e-10 66.6 2BYGM@1|root,2ZY98@2|Bacteria,4PCTC@976|Bacteroidetes,1IDBE@117743|Flavobacteriia,2NXY3@237|Flavobacterium 976|Bacteroidetes - - - - - - - - - - - - - - - k59_135012_4 1217710.F969_02563 8.8e-36 134.0 COG5377@1|root,COG5377@2|Bacteria,1MWP8@1224|Proteobacteria,1RN9Q@1236|Gammaproteobacteria,3NIHJ@468|Moraxellaceae 1236|Gammaproteobacteria L YqaJ-like viral recombinase domain - - - - - - - - - - - - YqaJ k59_52018_1 1121362.A605_04265 7.65e-11 71.2 COG0739@1|root,COG0739@2|Bacteria,2GM7Q@201174|Actinobacteria,22KEB@1653|Corynebacteriaceae 201174|Actinobacteria M Membrane proteins related to metalloendopeptidases mepA - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M23 k59_159367_2 497964.CfE428DRAFT_1294 1.8e-14 77.0 28HHC@1|root,2Z7T2@2|Bacteria,46VSN@74201|Verrucomicrobia 74201|Verrucomicrobia S AAA domain - - - - - - - - - - - - AAA_24 k59_2479_1 1048830.GUU_04164 2.95e-14 78.2 COG0714@1|root,COG0714@2|Bacteria,3WUGT@544448|Tenericutes 544448|Tenericutes O AAA domain (dynein-related subfamily) - - - - - - - - - - - - AAA k59_226142_1 375286.mma_2202 6.67e-84 258.0 28NGF@1|root,2Z9HT@2|Bacteria,1R9QF@1224|Proteobacteria,2VPSU@28216|Betaproteobacteria,47599@75682|Oxalobacteraceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_151634_1 696748.ASU2_02560 2.42e-38 137.0 COG4696@1|root,COG4696@2|Bacteria,1Q356@1224|Proteobacteria,1TFWD@1236|Gammaproteobacteria,1YACQ@135625|Pasteurellales 135625|Pasteurellales S Protein conserved in bacteria - - - - - - - - - - - - - k59_151634_3 1429767.W6ARJ8_9CAUD 6.51e-113 345.0 4QBY0@10239|Viruses,4QW35@35237|dsDNA viruses no RNA stage,4QQ4Q@28883|Caudovirales,4QNNN@10744|Podoviridae 10744|Podoviridae S UvrD-like helicase C-terminal domain - - - - - - - - - - - - - k59_35231_2 1047013.AQSP01000144_gene866 9.11e-23 106.0 COG0500@1|root,COG1216@1|root,COG1216@2|Bacteria,COG2226@2|Bacteria,2NPQ4@2323|unclassified Bacteria 2|Bacteria J Glycosyltransferase like family 2 - - - ko:K20444 - - - - ko00000,ko01000,ko01005,ko02000 4.D.1.3 GT2,GT4 - Glycos_transf_2 k59_27393_1 351016.RAZWK3B_16615 2.23e-17 93.6 2FFRP@1|root,347NW@2|Bacteria,1P2BR@1224|Proteobacteria,2UVQC@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_152882_1 691965.D4P7C5_9CAUD 6.58e-106 323.0 4QBV3@10239|Viruses,4QW0W@35237|dsDNA viruses no RNA stage,4QPPJ@28883|Caudovirales,4QKW5@10699|Siphoviridae 10699|Siphoviridae S Phage Terminase - - - - - - - - - - - - - k59_260509_2 105154.Q9MBU6_9VIRU 7.99e-83 264.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_60775_1 2003327.CAPSD_BPCHP 5.32e-34 130.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_219653_1 1609634.A0A0C5AFT2_9VIRU 1.14e-47 165.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_227232_1 1480731.X2KUJ0_9CAUD 1.24e-14 84.7 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_202220_1 1336237.JAEE01000001_gene2118 2.83e-23 105.0 2DM98@1|root,327XW@2|Bacteria,1RH12@1224|Proteobacteria,1S1ES@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_69679_1 910314.HMPREF9220_0734 6.56e-55 191.0 COG0749@1|root,COG0749@2|Bacteria 2|Bacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity - - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - DNA_pol_A,RNase_H_2 k59_210136_2 1336243.JAEA01000002_gene2645 3.04e-43 149.0 28PTM@1|root,2ZCEU@2|Bacteria,1R5DD@1224|Proteobacteria,2TVG7@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Family of unknown function (DUF5309) - - - - - - - - - - - - DUF5309 k59_94202_2 1692257.A0A0K1RL39_9CIRC 2.99e-12 73.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_136235_1 1125863.JAFN01000001_gene1263 8.85e-36 129.0 2E8ZK@1|root,33394@2|Bacteria,1NFCZ@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_260716_1 1618247.A0A0C5IMK7_9CIRC 1.57e-05 52.8 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_202416_3 411154.GFO_2450 7.95e-79 262.0 COG5362@1|root,COG5362@2|Bacteria,4PMSS@976|Bacteroidetes,1IJZ1@117743|Flavobacteriia 976|Bacteroidetes S Terminase-like family - - - - - - - - - - - - Terminase_6 k59_202416_5 457405.FSDG_01579 1.27e-18 86.3 COG0863@1|root,COG0863@2|Bacteria 2|Bacteria L N-4 methylation of cytosine - - 2.1.1.72 ko:K03497,ko:K07316 - - - - ko00000,ko01000,ko02048,ko03000,ko03036,ko04812 - - - N6_N4_Mtase,ParBc k59_111484_1 1589297.A0A0B5H2N7_9CAUD 5.82e-47 187.0 4QAXA@10239|Viruses,4QQ1A@28883|Caudovirales,4QNU7@10744|Podoviridae 10744|Podoviridae S metallopeptidase activity - - - - - - - - - - - - - k59_219941_1 1385658.U5KNR1_9VIRU 4e-55 184.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_3975_1 1129374.AJE_05001 5.03e-28 109.0 COG2188@1|root,COG2188@2|Bacteria 2|Bacteria K DNA-binding transcription factor activity - - - - - - - - - - - - DnaB_2,GntR,UTRA k59_95297_1 1238190.AMQY01000021_gene1570 6.26e-10 67.8 COG3170@1|root,COG3170@2|Bacteria,1R69E@1224|Proteobacteria 1224|Proteobacteria NU Phage P22-like portal protein - - - - - - - - - - - - P22_portal k59_170983_2 1161401.ASJA01000008_gene1658 6.82e-07 55.8 2CJWY@1|root,33MF9@2|Bacteria,1NKUU@1224|Proteobacteria,2UMVZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_170983_5 1430440.MGMSRv2_3476 7.55e-46 159.0 COG1442@1|root,COG1442@2|Bacteria,1QH4S@1224|Proteobacteria,2U2NZ@28211|Alphaproteobacteria,2JTII@204441|Rhodospirillales 204441|Rhodospirillales M glycosyl transferase family 8 - - - - - - - - - - - - - k59_20504_1 1429916.X566_20010 1.87e-26 104.0 COG1917@1|root,COG1917@2|Bacteria,1N6Q0@1224|Proteobacteria,2UKI2@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Cupin 2, conserved barrel domain protein - - - - - - - - - - - - - k59_20504_2 329254.Q2NPF7_9CAUD 4.62e-23 93.2 4QB0U@10239|Viruses,4QZQJ@35237|dsDNA viruses no RNA stage,4QR5X@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_29920_4 1609634.A0A0C5AFT2_9VIRU 2.05e-98 298.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_29920_6 1609634.A0A0C5AFV4_9VIRU 1.09e-203 585.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_252762_2 319003.Bra1253DRAFT_02456 2.6e-31 124.0 COG0741@1|root,COG0741@2|Bacteria,1MX5R@1224|Proteobacteria,2TVHC@28211|Alphaproteobacteria,3JUU6@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Transglycosylase SLT domain - - - - - - - - - - - - SLT k59_244502_2 1219035.NT2_13_00580 1.18e-68 231.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_146412_1 644076.SCH4B_3642 9.66e-08 55.8 COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,2TQZV@28211|Alphaproteobacteria,4NA3K@97050|Ruegeria 28211|Alphaproteobacteria L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parE - - ko:K02622 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim k59_146412_9 1122135.KB893169_gene2483 1.05e-09 58.5 COG0741@1|root,COG0741@2|Bacteria,1N1XZ@1224|Proteobacteria,2UB2Y@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Transglycosylase SLT domain - - - - - - - - - - - - SLT k59_12506_5 1548903.A0A0A1IWQ8_9CAUD 7.95e-69 219.0 4QAIK@10239|Viruses,4QPEB@28883|Caudovirales 28883|Caudovirales S phosphoprotein phosphatase activity - - - - - - - - - - - - - k59_228709_1 1502851.FG93_04276 2.22e-06 52.8 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase - - - - - - - - - - - - Methyltransf_11,Methyltransf_23 k59_203833_1 1609634.A0A0C5AFV4_9VIRU 9.91e-43 152.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_178884_1 411473.RUMCAL_00274 8.09e-39 144.0 COG0553@1|root,COG0553@2|Bacteria,1TP2C@1239|Firmicutes,24DVA@186801|Clostridia,3WP9W@541000|Ruminococcaceae 186801|Clostridia KL DEAD-like helicases superfamily - - - - - - - - - - - - Helicase_C,N6_N4_Mtase,SNF2_N k59_187226_1 279714.FuraDRAFT_0273 1.39e-42 160.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2VJKE@28216|Betaproteobacteria,2KQ0H@206351|Neisseriales 206351|Neisseriales S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_87680_2 1384056.N787_06840 5.26e-07 56.2 COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,1RMS8@1236|Gammaproteobacteria,1X4NS@135614|Xanthomonadales 135614|Xanthomonadales M Lytic murein transglycosylase slt - - ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 - SLT,SLT_L k59_63122_1 1211035.CD30_13030 1.09e-09 67.0 COG3378@1|root,COG3378@2|Bacteria,1TQP9@1239|Firmicutes,4HBTB@91061|Bacilli,3IYPQ@400634|Lysinibacillus 91061|Bacilli S DNA primase - - - ko:K06919 - - - - ko00000 - - - D5_N,Pox_D5,RepB_primase,Toprim_4,zf-CHC2 k59_188978_2 1122135.KB893135_gene619 6.87e-30 120.0 COG0507@1|root,COG0507@2|Bacteria,1R1AT@1224|Proteobacteria,2U1ZX@28211|Alphaproteobacteria 28211|Alphaproteobacteria L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD - - - - - - - - - - - - Terminase_6 k59_223084_1 1788443.A0A190WHB4_9CIRC 1.91e-14 79.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_263432_1 913970.F8RW84_9VIRU 3.52e-05 50.1 4QCVK@10239|Viruses,4QUMV@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_163371_1 1055815.AYYA01000051_gene1379 9.54e-111 330.0 COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,1RQ0H@1236|Gammaproteobacteria,3NIF7@468|Moraxellaceae 1236|Gammaproteobacteria E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine thrC GO:0003674,GO:0003824,GO:0004795,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - iLF82_1304.LF82_2261,iNRG857_1313.NRG857_00025 PALP,Thr_synth_N k59_13908_1 551789.ATVJ01000001_gene1805 1.1e-22 101.0 COG1573@1|root,COG1573@2|Bacteria,1MW8T@1224|Proteobacteria,2TSAR@28211|Alphaproteobacteria,43XC4@69657|Hyphomonadaceae 28211|Alphaproteobacteria L Domain of unknown function (DUF4130 - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - DUF4130,UDG k59_123007_1 428125.CLOLEP_03531 1.71e-13 74.3 COG0476@1|root,COG0476@2|Bacteria,1V9AZ@1239|Firmicutes,24H39@186801|Clostridia,3WP2B@541000|Ruminococcaceae 186801|Clostridia H ThiF family - - - - - - - - - - - - ThiF k59_254162_1 1347342.BN863_28980 2.51e-146 440.0 COG2801@1|root,COG2801@2|Bacteria,4NHY3@976|Bacteroidetes,1IIAC@117743|Flavobacteriia 976|Bacteroidetes L Transposase and inactivated derivatives - - - - - - - - - - - - rve k59_105511_1 1121937.AUHJ01000007_gene1940 1.95e-43 155.0 COG4653@1|root,COG4653@2|Bacteria,1MWU1@1224|Proteobacteria,1S0F5@1236|Gammaproteobacteria,467AV@72275|Alteromonadaceae 1236|Gammaproteobacteria S Phage capsid family - - - - - - - - - - - - Phage_capsid k59_38783_1 1609634.A0A0C5AFV4_9VIRU 1.36e-131 394.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_139418_1 622637.KE124774_gene3355 2.93e-10 60.8 COG3108@1|root,COG3108@2|Bacteria,1RICX@1224|Proteobacteria,2UDAG@28211|Alphaproteobacteria,36Z2Z@31993|Methylocystaceae 28211|Alphaproteobacteria S D-alanyl-D-alanine carboxypeptidase - - - ko:K17733 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M15_4 k59_97833_6 888743.HMPREF9141_0984 6.37e-07 55.8 2EVUA@1|root,33P81@2|Bacteria,4P82D@976|Bacteroidetes,2FV68@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_238761_1 105154.Q9MBU6_9VIRU 1.43e-114 347.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_255633_3 1298608.JCM18900_13069 3.14e-67 213.0 COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,1RNJK@1236|Gammaproteobacteria,3NN1F@468|Moraxellaceae 1236|Gammaproteobacteria D VirC1 protein parA - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31,MipZ k59_197701_1 1498011.A0A096XUX6_9CAUD 1.85e-81 266.0 4QCZC@10239|Viruses,4QRH3@28883|Caudovirales 28883|Caudovirales S Bacterial DNA polymerase III alpha subunit - - - - - - - - - - - - - k59_81969_1 1298858.AUEL01000029_gene80 3.04e-08 63.9 2C2IA@1|root,2ZW5P@2|Bacteria,1PB15@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_140944_1 1692244.A0A0K1RLR5_9CIRC 3.92e-98 295.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_140944_2 1692244.A0A0K1RL64_9CIRC 1.48e-21 104.0 4QHEE@10239|Viruses,4QUMH@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_15221_2 307480.IW16_26365 4.09e-09 62.0 COG1961@1|root,COG1961@2|Bacteria,4NJM8@976|Bacteroidetes,1I0IY@117743|Flavobacteriia,3ZRIH@59732|Chryseobacterium 976|Bacteroidetes L Resolvase, N terminal domain - - - - - - - - - - - - HTH_7,Resolvase k59_23586_1 145579.CAPSD_BPPHM 1.06e-31 128.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_15227_1 1379719.S5TMX6_9CIRC 1.92e-12 70.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_106706_2 429009.Adeg_0117 5.23e-05 45.4 COG1396@1|root,COG1396@2|Bacteria,1VDXU@1239|Firmicutes,24PKB@186801|Clostridia,42IK3@68295|Thermoanaerobacterales 186801|Clostridia K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 k59_40175_1 315730.BcerKBAB4_5695 6.44e-10 61.6 COG0317@1|root,COG0317@2|Bacteria,1VC5K@1239|Firmicutes,4IEB3@91061|Bacilli,1ZKCS@1386|Bacillus 91061|Bacilli KT COG0317 Guanosine polyphosphate pyrophosphohydrolases synthetases - - - - - - - - - - - - - k59_40299_3 1385658.U5KNR1_9VIRU 4.89e-78 247.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_207083_1 42565.FP66_04570 2.94e-71 229.0 29UKS@1|root,30FY7@2|Bacteria,1RGKW@1224|Proteobacteria,1SKMS@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_207083_2 1121413.JMKT01000011_gene2317 5.65e-36 129.0 2ECFT@1|root,336E2@2|Bacteria,1NDA7@1224|Proteobacteria,431R6@68525|delta/epsilon subdivisions,2WW7A@28221|Deltaproteobacteria 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_40304_2 1609634.A0A0C5AFV4_9VIRU 7.19e-63 212.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_157401_2 1235794.C811_01273 3.05e-08 60.5 COG0338@1|root,COG3392@1|root,COG0338@2|Bacteria,COG3392@2|Bacteria,2I9YW@201174|Actinobacteria 201174|Actinobacteria L D12 class N6 adenine-specific DNA methyltransferase - - 2.1.1.72 ko:K06223,ko:K07318 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 k59_90534_1 1041142.ATTP01000043_gene5286 4.56e-47 162.0 2C22H@1|root,305QB@2|Bacteria,1RFAD@1224|Proteobacteria,2U8GY@28211|Alphaproteobacteria,4BEFE@82115|Rhizobiaceae 28211|Alphaproteobacteria S Chaperone of endosialidase - - - - - - - - - - - - Peptidase_S74 k59_265192_1 1618237.A0A0C5IMG6_9CIRC 8.48e-17 84.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_265192_2 1618248.A0A0C5IB82_9CIRC 5.2e-17 80.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_91352_8 953739.SVEN_4145 2.35e-12 76.6 2BZJP@1|root,33QCI@2|Bacteria,2IFNW@201174|Actinobacteria 201174|Actinobacteria S Hyaluronidase protein (HylP) - - - - - - - - - - - - Hyaluronidase_1 k59_91352_10 1486472.A0A068F3I8_9CAUD 7.92e-102 318.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QM52@10699|Siphoviridae 10699|Siphoviridae S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor - - - - - - - - - - - - - k59_215739_1 105154.Q9MBU6_9VIRU 2.39e-140 419.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_232380_1 1123263.AUKY01000086_gene1006 1.08e-40 150.0 28MKK@1|root,2ZAWR@2|Bacteria,1UYAT@1239|Firmicutes,3VSD5@526524|Erysipelotrichia 526524|Erysipelotrichia S Putative viral replication protein - - - - - - - - - - - - RNA_helicase,Viral_Rep k59_49911_2 1166948.JPZL01000002_gene1845 6.86e-57 187.0 28W6R@1|root,2ZI7D@2|Bacteria,1N49N@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_257244_1 879305.HMPREF9290_0439 1.71e-08 63.2 COG0209@1|root,COG1327@1|root,COG0209@2|Bacteria,COG1327@2|Bacteria,1TPFH@1239|Firmicutes,249EN@186801|Clostridia,22GE3@1570339|Peptoniphilaceae 186801|Clostridia F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdA - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,RNR_N,Ribonuc_red_lgC,Ribonuc_red_lgN k59_190868_1 583355.Caka_2337 1.65e-11 72.4 COG1674@1|root,COG1674@2|Bacteria,46UAV@74201|Verrucomicrobia,3K7KD@414999|Opitutae 414999|Opitutae D Belongs to the FtsK SpoIIIE SftA family - - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_SpoIIIE,Ftsk_gamma k59_8463_1 1165094.RINTHH_3920 2.54e-65 213.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_8463_4 1986029.Q9MBM7_9VIRU 7.72e-14 75.1 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_8463_5 105154.Q9MBU6_9VIRU 1.83e-128 385.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_116295_1 335284.Pcryo_0254 4.8e-84 256.0 COG2207@1|root,COG2207@2|Bacteria,1MY46@1224|Proteobacteria,1T1QD@1236|Gammaproteobacteria,3NTA8@468|Moraxellaceae 1236|Gammaproteobacteria K Cupin - - - ko:K21747 - - - - ko00000,ko03000 - - - Cupin_6,HTH_18,HTH_AraC k59_99617_8 1385658.U5KNR1_9VIRU 4.36e-09 66.2 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_207478_2 136084.Q9G0G5_9CAUD 1.69e-41 152.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QNQ6@10744|Podoviridae 10744|Podoviridae S ribonucleoside-triphosphate reductase activity - - - - - - - - - - - - - k59_9129_5 1609634.A0A0C5AFV4_9VIRU 4.67e-169 496.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_25839_1 1265310.CCBD010000081_gene5127 5.15e-09 64.3 COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,2IBWG@201174|Actinobacteria,236HX@1762|Mycobacteriaceae 201174|Actinobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_tranf_2_3,Glycos_transf_1 k59_17226_1 691965.D4P7L7_9CAUD 6.52e-256 739.0 4QB9J@10239|Viruses,4QXFE@35237|dsDNA viruses no RNA stage,4QS1Z@28883|Caudovirales,4QN8F@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_17226_2 691965.D4P7L6_9CAUD 1.62e-66 208.0 4QFKG@10239|Viruses,4QV77@35237|dsDNA viruses no RNA stage,4QR6Q@28883|Caudovirales,4QMGT@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_17226_3 691965.D4P7L5_9CAUD 3.25e-32 115.0 4QG3V@10239|Viruses,4QW5T@35237|dsDNA viruses no RNA stage,4QSWE@28883|Caudovirales,4QM1Q@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_34139_2 1173297.I1VXD8_9CAUD 2.4e-10 59.7 4QEQK@10239|Viruses,4QWG7@35237|dsDNA viruses no RNA stage,4QPEJ@28883|Caudovirales,4QIV7@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_108652_1 1236959.BAMT01000009_gene3358 2.58e-06 54.7 COG2520@1|root,COG2520@2|Bacteria,1RIYU@1224|Proteobacteria,2VWI0@28216|Betaproteobacteria 28216|Betaproteobacteria M Methyltransferase FkbM family - - - - - - - - - - - - Methyltransf_21 k59_216621_1 999550.KI421507_gene3095 1.24e-11 70.9 COG0463@1|root,COG0463@2|Bacteria,1R4XG@1224|Proteobacteria,2TZ9Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 k59_92132_1 1220601.L7TLT7_9CAUD 3.97e-92 285.0 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales,4QI76@10662|Myoviridae 10662|Myoviridae S DNA helicase activity - - - - - - - - - - - - - k59_1010_1 1692242.A0A0K1RKZ2_9CIRC 2.46e-40 145.0 4QFEW@10239|Viruses,4QUKZ@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_133600_2 1692250.A0A0K1RLR1_9CIRC 2.03e-90 278.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_141941_3 1986029.Q9MBM3_9VIRU 1.28e-51 176.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_199809_1 1122132.AQYH01000015_gene2272 3.92e-71 229.0 2C5GI@1|root,2Z8C1@2|Bacteria,1R8XM@1224|Proteobacteria,2TUME@28211|Alphaproteobacteria,4BJKS@82115|Rhizobiaceae 28211|Alphaproteobacteria S P22 coat protein - gene protein 5 - - - - - - - - - - - - P22_CoatProtein k59_158295_1 105154.Q9MBU3_9VIRU 2.8e-06 51.2 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_158295_2 105154.Q9MBU6_9VIRU 3.02e-26 107.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_207991_1 105154.Q9MBU3_9VIRU 4.07e-17 83.2 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_207991_3 115711.CP_0543 3.74e-15 76.6 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_207991_4 105154.Q9MBT9_9VIRU 2.9e-16 73.9 4QCC5@10239|Viruses,4QUKW@29258|ssDNA viruses,4QP4C@10841|Microviridae 10841|Microviridae S viral process - - - - - - - - - - - - - k59_207991_5 1385658.U5KPZ6_9VIRU 5.17e-209 598.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_116978_1 637389.Acaty_c0101 2.38e-62 213.0 COG3378@1|root,COG3378@2|Bacteria,1MV7I@1224|Proteobacteria,1RRN5@1236|Gammaproteobacteria 1236|Gammaproteobacteria L D5 N terminal like - - - ko:K06919 - - - - ko00000 - - - D5_N,Pox_D5,PriCT_1,PriCT_2,Toprim_2 k59_83695_2 1340709.S5WCQ6_9CAUD 2.33e-43 148.0 4QF2I@10239|Viruses,4QZUC@35237|dsDNA viruses no RNA stage,4QTZV@28883|Caudovirales,4QMSD@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_174709_2 1609634.A0A0C5ANA6_9VIRU 2.81e-16 81.3 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_199891_1 935261.JAGL01000009_gene1180 4.57e-14 75.1 2AFZH@1|root,3163D@2|Bacteria,1RJUP@1224|Proteobacteria,2UI0N@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_199891_2 1220601.L7TJ68_9CAUD 1.04e-45 152.0 4QASP@10239|Viruses,4QVR8@35237|dsDNA viruses no RNA stage,4QR4Z@28883|Caudovirales 28883|Caudovirales S deoxyribonuclease IV (phage-T4-induced) activity - - - - - - - - - - - - - k59_9235_6 145579.C_BPPHM 7.86e-15 71.2 4QCC5@10239|Viruses,4QUKW@29258|ssDNA viruses,4QP4C@10841|Microviridae 10841|Microviridae S viral process - - - - - - - - - - - - - k59_9235_7 186617.M9M8L2_9VIRU 7.36e-93 291.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_34251_1 1609634.A0A0C5AFV4_9VIRU 3.47e-48 172.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_200959_1 1121441.AUCX01000014_gene507 2.41e-14 80.1 COG5563@1|root,COG5563@2|Bacteria,1Q0JE@1224|Proteobacteria,430IH@68525|delta/epsilon subdivisions,2X0GF@28221|Deltaproteobacteria,2MD65@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_168028_3 105154.Q9MBU6_9VIRU 0.000925 41.6 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_226048_2 1385658.U5KNR1_9VIRU 2.12e-75 241.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_76854_1 1121459.AQXE01000001_gene2765 1.61e-16 87.0 COG0749@1|root,COG0749@2|Bacteria,1P27P@1224|Proteobacteria,42YUP@68525|delta/epsilon subdivisions,2WTS1@28221|Deltaproteobacteria,2MAPB@213115|Desulfovibrionales 28221|Deltaproteobacteria L DNA polymerase A domain - - - - - - - - - - - - DNA_pol_A k59_52035_1 1197951.I6RT10_9CAUD 3.87e-34 134.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales 28883|Caudovirales S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_201095_1 371042.NG99_26200 6.6e-25 107.0 COG4695@1|root,COG4695@2|Bacteria,1N389@1224|Proteobacteria,1SNRA@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Portal protein - - - - - - - - - - - - - k59_201095_2 460265.Mnod_4078 1.56e-57 194.0 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,2U6BJ@28211|Alphaproteobacteria,1JZ7Y@119045|Methylobacteriaceae 28211|Alphaproteobacteria S TIGRFAM phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_52037_2 411460.RUMTOR_01350 0.000182 46.6 2EAAT@1|root,334F2@2|Bacteria,1VJJI@1239|Firmicutes,24TQU@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_68346_3 1385658.U5KPZ6_9VIRU 4.62e-89 281.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_126818_3 1385658.U5KNR1_9VIRU 5.3e-39 143.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_192426_1 1609634.A0A0C5AFV4_9VIRU 3.03e-95 295.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_192426_3 1609634.A0A0C5AFT2_9VIRU 1.39e-134 392.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_192426_7 1609634.A0A0C5ANA6_9VIRU 4.49e-20 91.3 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_93183_3 1502851.FG93_01932 5.74e-14 84.3 2DPZ1@1|root,3340X@2|Bacteria,1R2EE@1224|Proteobacteria,2TZIB@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_93183_6 1304877.KI519399_gene5000 3.68e-113 357.0 28S81@1|root,2ZEJD@2|Bacteria,1RCNN@1224|Proteobacteria,2UUXX@28211|Alphaproteobacteria,3K50D@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_126820_1 445688.E3SNL2_9CAUD 1.19e-43 166.0 4QEE7@10239|Viruses,4QV59@35237|dsDNA viruses no RNA stage,4QPT7@28883|Caudovirales,4QI2X@10662|Myoviridae 10662|Myoviridae S Pfam:DUF4815 - - - - - - - - - - - - - k59_226158_1 1238190.AMQY01000021_gene1593 1.93e-63 220.0 COG0749@1|root,COG0749@2|Bacteria,1MWX7@1224|Proteobacteria,1S0Q1@1236|Gammaproteobacteria 1236|Gammaproteobacteria L ORF located using Glimmer RBSfinder - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A,DNA_pol_A_exo1 k59_19265_1 1121921.KB898706_gene3039 6.49e-88 276.0 COG1783@1|root,COG1783@2|Bacteria,1R66A@1224|Proteobacteria,1RQFD@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage terminase, large subunit Z012_12305 - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C k59_102706_1 1385658.U5KPZ6_9VIRU 1.18e-142 426.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_119736_1 1121935.AQXX01000130_gene2425 4.82e-44 147.0 2AD08@1|root,312N7@2|Bacteria,1NDC4@1224|Proteobacteria,1SAPT@1236|Gammaproteobacteria,1XQHK@135619|Oceanospirillales 135619|Oceanospirillales S Holin of 3TMs, for gene-transfer release - - - - - - - - - - - - GTA_holin_3TM k59_177326_1 521674.Plim_4265 4.19e-08 65.5 29XN2@1|root,30JDF@2|Bacteria,2J498@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - k59_202296_1 1087448.Eab7_2553 2.37e-09 63.5 COG2199@1|root,COG2199@2|Bacteria,1V0AY@1239|Firmicutes,4HEN2@91061|Bacilli 91061|Bacilli T Diguanylate cyclase - - - - - - - - - - - - GGDEF,PAS_8,PAS_9 k59_28600_5 1234888.K0A2J2_9VIRU 4.35e-141 421.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_251508_1 691965.D4P7I3_9CAUD 3.02e-82 276.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_193489_1 105154.Q9MBU6_9VIRU 1.48e-71 232.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_193489_2 1609634.A0A0C5ANA6_9VIRU 1.06e-10 65.9 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_45047_3 477184.KYC_12543 4.48e-25 106.0 2DIG9@1|root,3036R@2|Bacteria,1RBPA@1224|Proteobacteria,2WH3R@28216|Betaproteobacteria,3T9JP@506|Alcaligenaceae 28216|Betaproteobacteria L YqaJ-like viral recombinase domain - - 3.1.11.3 ko:K01143 - - - - ko00000,ko01000 - - - YqaJ k59_61995_3 105154.Q9MBU6_9VIRU 1.94e-141 426.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_20525_3 1123274.KB899428_gene1842 1.06e-08 60.5 COG1475@1|root,COG1475@2|Bacteria,2J7KN@203691|Spirochaetes 203691|Spirochaetes K ParB-like nuclease domain - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_113010_2 106648.BBLJ01000014_gene1425 5.65e-11 66.6 COG3206@1|root,COG3206@2|Bacteria,1ND5H@1224|Proteobacteria,1RNXC@1236|Gammaproteobacteria,3NSVB@468|Moraxellaceae 1236|Gammaproteobacteria M protein involved in exopolysaccharide biosynthesis - - - - - - - - - - - - Rad52_Rad22 k59_171007_1 1234888.K0A2J2_9VIRU 1.93e-50 176.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_86735_1 158500.BV97_04210 3.92e-09 64.3 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2TRJF@28211|Alphaproteobacteria,2K1KW@204457|Sphingomonadales 204457|Sphingomonadales L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_228866_1 317936.Nos7107_0420 4.26e-05 51.2 COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1FZVR@1117|Cyanobacteria,1HTVE@1161|Nostocales 1117|Cyanobacteria T SPTR ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein - - - - - - - - - - - - HATPase_c,HisKA,Response_reg k59_154477_1 1382315.JPOI01000001_gene269 2.3e-05 50.1 COG1388@1|root,COG1876@1|root,COG1388@2|Bacteria,COG1876@2|Bacteria,1V8X4@1239|Firmicutes,4I29S@91061|Bacilli,1WHJU@129337|Geobacillus 91061|Bacilli M D-alanyl-D-alanine carboxypeptidase - - - ko:K17733 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M15_4 k59_79254_3 270374.MELB17_09838 4.02e-11 67.4 COG0210@1|root,COG0210@2|Bacteria,1R4PV@1224|Proteobacteria,1RZXT@1236|Gammaproteobacteria 1236|Gammaproteobacteria L DNA helicase - - - - - - - - - - - - AAA_19,DUF87,UvrD-helicase,UvrD_C k59_236102_1 12336.Q331U1_CBCP 3.21e-07 59.7 4QBNM@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales 28883|Caudovirales S N-methyltransferase activity - - - - - - - - - - - - - k59_129876_3 411470.RUMGNA_02049 9.19e-25 98.6 2C6KN@1|root,32Y69@2|Bacteria,1VANX@1239|Firmicutes,24MNG@186801|Clostridia,3Y12A@572511|Blautia 186801|Clostridia S VRR-NUC domain - - - - - - - - - - - - VRR_NUC k59_129876_4 272560.BPSL1666 9.09e-59 206.0 COG0457@1|root,COG0500@1|root,COG0859@1|root,COG0457@2|Bacteria,COG0859@2|Bacteria,COG2226@2|Bacteria,1MUZK@1224|Proteobacteria,2VJNV@28216|Betaproteobacteria,1K0WR@119060|Burkholderiaceae 28216|Betaproteobacteria M repeat-containing protein - - - - - - - - - - - - Glyco_transf_9,TPR_1,TPR_16 k59_121305_1 1692257.A0A0K1RL39_9CIRC 7.15e-29 115.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_161991_2 1379698.RBG1_1C00001G1832 2.41e-43 148.0 COG0741@1|root,COG0741@2|Bacteria 2|Bacteria M lytic transglycosylase activity trwN - - ko:K03194,ko:K08307,ko:K08309,ko:K12089 ko03070,ko05120,map03070,map05120 M00333,M00564 - - ko00000,ko00001,ko00002,ko01000,ko01011,ko02044 3.A.7.12.1 GH23 - LysM,SLT k59_62099_1 1574422.A0A0A1ENW9_9CIRC 1.74e-24 112.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_194917_2 511.JT27_18230 1.12e-215 624.0 2F26G@1|root,33V4S@2|Bacteria,1NUS1@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_20657_1 1692257.A0A0K1RL39_9CIRC 3.44e-45 158.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_20657_3 1618248.A0A0C5IB82_9CIRC 5.29e-43 149.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_115211_1 348824.LPU83_1704 1.1e-55 194.0 2BSKA@1|root,32MNV@2|Bacteria,1PFD2@1224|Proteobacteria,2V6B6@28211|Alphaproteobacteria,4BGN5@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_173130_3 186617.M9M8L2_9VIRU 3.38e-18 87.8 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_7717_1 1121381.JNIV01000006_gene675 1.6e-07 54.3 COG2189@1|root,COG2189@2|Bacteria 2|Bacteria L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.72,3.1.21.3 ko:K01154,ko:K03933,ko:K07316 - - - - ko00000,ko01000,ko02048 - AA10,CBM73 - N6_N4_Mtase,PT k59_230476_4 2003327.CAPSD_BPCHP 8.55e-28 116.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_123339_2 1788455.A0A190WHF5_9CIRC 2.51e-24 104.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_7719_1 1041147.AUFB01000009_gene1861 7.74e-42 157.0 2F5UF@1|root,33YDD@2|Bacteria,1PH7C@1224|Proteobacteria,2V8WS@28211|Alphaproteobacteria,4BKM2@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_22369_1 195253.Syn6312_1179 1.37e-68 245.0 COG0419@1|root,COG0419@2|Bacteria 2|Bacteria L ATPase involved in DNA repair - - 2.7.11.1 ko:K03546,ko:K12132 - - - - ko00000,ko01000,ko01001,ko03400 - - - AAA_23,Pkinase,SMC_N k59_223609_1 986075.CathTA2_1798 3.82e-06 49.3 COG1351@1|root,COG1351@2|Bacteria,1TRHD@1239|Firmicutes,4HTFB@91061|Bacilli 91061|Bacilli F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - 2.1.1.148 ko:K03465 ko00240,ko00670,ko01100,map00240,map00670,map01100 - R06613 RC00022,RC00332 ko00000,ko00001,ko01000 - - - Thy1 k59_223609_4 444875.E3SMI1_9CAUD 9.23e-55 198.0 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales,4QNBW@10744|Podoviridae 10744|Podoviridae S DNA helicase activity - - - - - - - - - - - - - k59_156421_1 1175654.A0A0S0N897_9CAUD 4.65e-95 296.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QM52@10699|Siphoviridae 10699|Siphoviridae S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor - - - - - - - - - - - - - k59_213002_1 1385658.U5KQQ9_9VIRU 2.85e-14 75.5 4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_180796_1 1788444.A0A190WHB9_9CIRC 9.7e-57 189.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_180796_2 1692244.A0A0K1RLR5_9CIRC 1.81e-20 95.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_214400_1 1027292.HMPREF9372_3394 1.05e-33 126.0 COG1235@1|root,COG1235@2|Bacteria,1TSJF@1239|Firmicutes,4HB1R@91061|Bacilli,26DYE@186818|Planococcaceae 91061|Bacilli S Beta-lactamase superfamily domain - - - - - - - - - - - - Lactamase_B_2 k59_214400_5 264462.Bd0704 7.86e-07 61.6 COG2911@1|root,COG3209@1|root,COG2911@2|Bacteria,COG3209@2|Bacteria,1QVEQ@1224|Proteobacteria 1224|Proteobacteria M Chaperone of endosialidase - - - - - - - - - - - - Peptidase_S74 k59_264928_1 1165094.RINTHH_3920 1.48e-23 100.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_264928_4 1609634.A0A0C5ANA6_9VIRU 0.000181 49.3 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_264928_5 105154.Q9MBU6_9VIRU 3.84e-202 581.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_24350_1 575540.Isop_2443 4.7e-52 183.0 COG1061@1|root,COG1061@2|Bacteria,2J0ES@203682|Planctomycetes 203682|Planctomycetes L COGs COG1061 DNA or RNA helicase of superfamily II - - - ko:K19789 - - - - ko00000,ko03400 - - - Helicase_C,ResIII k59_98426_1 1321779.HMPREF1984_00660 9.02e-05 52.4 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,378G8@32066|Fusobacteria 32066|Fusobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,HHH_5 k59_182321_3 1236000.L0ASJ4_9CAUD 1.59e-17 85.9 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QI9F@10662|Myoviridae 10662|Myoviridae S Type III restriction enzyme, res subunit - - - - - - - - - - - - - k59_239528_2 1298858.AUEL01000029_gene83 1.1e-13 72.4 2DM1W@1|root,32UG2@2|Bacteria,1N0YN@1224|Proteobacteria,2VD59@28211|Alphaproteobacteria,43KUT@69277|Phyllobacteriaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_247698_1 1121930.AQXG01000001_gene1548 9.08e-23 108.0 COG5164@1|root,COG5164@2|Bacteria,4NT5R@976|Bacteroidetes,1ISIJ@117747|Sphingobacteriia 976|Bacteroidetes K regulation of DNA-templated transcription, elongation - - - - - - - - - - - - LRR_5 k59_24356_1 1055815.AYYA01000044_gene2365 1.98e-102 330.0 COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,1RNA6@1236|Gammaproteobacteria,3NK8A@468|Moraxellaceae 1236|Gammaproteobacteria D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge k59_247702_3 1175654.A0A0S0N8I3_9CAUD 2.78e-07 52.4 4QCWX@10239|Viruses,4QYGT@35237|dsDNA viruses no RNA stage,4QU1G@28883|Caudovirales,4QMA7@10699|Siphoviridae 10699|Siphoviridae S Terminase-like family - - - - - - - - - - - - - k59_15972_1 1206545.S6CLP5_9CAUD 6.11e-22 98.6 4QCR0@10239|Viruses,4QVAV@35237|dsDNA viruses no RNA stage,4QPFK@28883|Caudovirales,4QI4N@10662|Myoviridae 10662|Myoviridae S cell wall macromolecule catabolic process - GO:0003674,GO:0003796,GO:0003824,GO:0004553,GO:0005488,GO:0005515,GO:0005575,GO:0008150,GO:0009405,GO:0009987,GO:0016043,GO:0016787,GO:0016798,GO:0019012,GO:0022607,GO:0033922,GO:0042802,GO:0043933,GO:0044085,GO:0044403,GO:0044409,GO:0044411,GO:0044419,GO:0044423,GO:0051259,GO:0051260,GO:0051701,GO:0051704,GO:0051828,GO:0051830,GO:0061783,GO:0065003,GO:0070206,GO:0070207,GO:0071840,GO:0085027,GO:0098015,GO:0098025 - - - - - - - - - - - k59_98437_2 105154.Q9MBU3_9VIRU 3e-11 63.9 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_264968_1 1788447.A0A190WHJ9_9CIRC 2.55e-14 80.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_264968_2 1618256.A0A0C5I294_9CIRC 1.3e-22 97.8 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_264968_5 291603.MREP_FBNY1 2.36e-15 77.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_247708_1 1122137.AQXF01000001_gene2540 6.63e-20 89.0 COG3756@1|root,COG3756@2|Bacteria,1NGB2@1224|Proteobacteria,2VGAH@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF1376) - - - - - - - - - - - - DUF1376 k59_40836_2 742733.HMPREF9469_05023 6e-52 171.0 2CGG9@1|root,2ZVSJ@2|Bacteria,1V633@1239|Firmicutes,24HD0@186801|Clostridia,222RY@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_40836_3 411460.RUMTOR_01342 4.5e-94 281.0 28NM4@1|root,2ZBMQ@2|Bacteria,1V1QD@1239|Firmicutes,24G1B@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_107114_1 1385658.U5KPZ6_9VIRU 1.16e-64 214.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_107114_4 1385658.U5KNR1_9VIRU 1.68e-25 107.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_107114_9 1609634.A0A0C5AFV4_9VIRU 6.71e-98 306.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_256340_1 1444711.CCJF01000003_gene10 1.17e-39 145.0 COG5362@1|root,COG5362@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Terminase_6,Terminase_6C k59_66540_3 273526.SMDB11_2614 8.9e-38 136.0 2CJWY@1|root,31CWF@2|Bacteria,1RKEF@1224|Proteobacteria,1S75P@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_66540_4 504346.B5WZS5_BPPAJ 1.52e-24 97.1 4QB12@10239|Viruses,4QV5M@35237|dsDNA viruses no RNA stage,4QPN3@28883|Caudovirales,4QKV7@10699|Siphoviridae 10699|Siphoviridae S Phage head-tail joining protein - - - - - - - - - - - - - k59_41756_1 857087.Metme_2331 5.75e-37 140.0 COG4128@1|root,COG4128@2|Bacteria,1N0I7@1224|Proteobacteria,1TBAY@1236|Gammaproteobacteria,1XG0Y@135618|Methylococcales 135618|Methylococcales S PFAM Zonular occludens toxin - - - ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko02042 - - - Zot k59_190952_1 1028800.RG540_CH13960 1.04e-07 51.6 2EVDQ@1|root,33NU5@2|Bacteria,1NQC2@1224|Proteobacteria,2UY7F@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_240712_1 1165094.RINTHH_3920 2.07e-52 182.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_99762_1 761193.Runsl_3452 6.22e-20 84.7 COG4696@1|root,COG4696@2|Bacteria,4NNW2@976|Bacteroidetes,47PPX@768503|Cytophagia 976|Bacteroidetes S PFAM Phosphoribosyl-ATP pyrophosphohydrolase - - - - - - - - - - - - PRA-PH k59_8583_3 105154.Q9MBU6_9VIRU 6.26e-119 362.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_249084_5 1123360.thalar_00016 6.17e-76 247.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2TS19@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdZ - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_lgC,Ribonuc_red_lgN k59_8587_1 1379709.S5TMV0_9CIRC 2.45e-27 109.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_124710_1 1123227.KB899347_gene928 1.1e-29 128.0 COG1783@1|root,COG1783@2|Bacteria,1R66A@1224|Proteobacteria,2TV42@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Terminase large subunit - - - ko:K06909 - - - - ko00000 - - - Terminase_3 k59_141223_4 643562.Daes_2400 2.5e-10 62.8 COG4387@1|root,COG4387@2|Bacteria,1N1K0@1224|Proteobacteria,42W85@68525|delta/epsilon subdivisions,2WRV3@28221|Deltaproteobacteria,2MD2H@213115|Desulfovibrionales 28221|Deltaproteobacteria S Protein of unknown function (DUF1320) - - - - - - - - - - - - DUF1320 k59_207570_2 378806.STAUR_2852 3.19e-07 58.9 COG4675@1|root,COG4675@2|Bacteria,1QZI2@1224|Proteobacteria,43CJ5@68525|delta/epsilon subdivisions,2X7TG@28221|Deltaproteobacteria,2Z2C8@29|Myxococcales 28221|Deltaproteobacteria S tail collar domain protein - - - - - - - - - - - - - k59_108112_1 186617.M9M8L2_9VIRU 1.06e-08 60.1 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_257432_4 1609634.A0A0C5AFV4_9VIRU 9.95e-67 219.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_124764_1 621372.ACIH01000214_gene1012 3.88e-09 64.3 2BUJY@1|root,32PWF@2|Bacteria,1VP06@1239|Firmicutes,4I0WX@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k59_74983_1 1192034.CAP_3634 1.87e-11 74.3 29XKS@1|root,30JBZ@2|Bacteria,1PVMU@1224|Proteobacteria,435HX@68525|delta/epsilon subdivisions,2X9A0@28221|Deltaproteobacteria,2Z2UD@29|Myxococcales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_74983_3 351348.Maqu_0543 1.16e-11 66.2 COG2063@1|root,COG2063@2|Bacteria 2|Bacteria N Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation - - - ko:K02393 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlgH k59_133477_6 234267.Acid_0568 1.63e-56 205.0 COG2192@1|root,COG2192@2|Bacteria,3Y37V@57723|Acidobacteria 57723|Acidobacteria O Carbamoyltransferase C-terminus - - - ko:K00612 - - - - ko00000,ko01000 - - - Carbam_trans_C,Carbam_trans_N k59_133477_7 72019.SARC_05221T0 9.98e-22 106.0 28KVY@1|root,2RXKG@2759|Eukaryota 2759|Eukaryota S Bacterial protein of unknown function (HtrL_YibB) - - - - - - - - - - - - HtrL_YibB k59_34033_1 343516.Q286Z8_9CAUD 5.33e-38 146.0 4QGU6@10239|Viruses,4QYG2@35237|dsDNA viruses no RNA stage,4QPT8@28883|Caudovirales,4QP2X@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_249516_3 1238450.VIBNISOn1_1190014 1.38e-14 82.0 2C7BQ@1|root,33MPW@2|Bacteria,1NYCK@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_249516_4 1054968.G0X4U1_9CAUD 3.25e-17 84.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QNI0@10744|Podoviridae 10744|Podoviridae S viral capsid - GO:0005575,GO:0019012,GO:0019028,GO:0019030,GO:0039617,GO:0044423,GO:0046729 - - - - - - - - - - - k59_150058_4 1094553.MCS_01038 1.2e-08 65.9 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2TRJF@28211|Alphaproteobacteria,48T5Y@772|Bartonellaceae 28211|Alphaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_150058_6 1149133.ppKF707_0757 2.27e-21 94.4 COG0237@1|root,COG0237@2|Bacteria,1P8TB@1224|Proteobacteria,1TC1Y@1236|Gammaproteobacteria,1YJNV@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria H dephospho-CoA kinase activity - - - - - - - - - - - - - k59_67150_2 700939.E5FJ56_9CAUD 1.53e-12 72.8 4QBHW@10239|Viruses,4QW8N@35237|dsDNA viruses no RNA stage,4QTT7@28883|Caudovirales,4QJZQ@10662|Myoviridae 10662|Myoviridae S sequence-specific DNA binding transcription factor activity - - - - - - - - - - - - - k59_100316_1 753084.F4YCM7_9CAUD 8.1e-34 119.0 4QCEX@10239|Viruses,4QV7Q@35237|dsDNA viruses no RNA stage,4QU8B@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_199791_4 948071.S4S2D9_9CAUD 4.64e-222 635.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QNQ6@10744|Podoviridae 10744|Podoviridae S ribonucleoside-triphosphate reductase activity - - - - - - - - - - - - - k59_141901_1 32057.KB217478_gene4378 1.48e-12 72.4 COG1403@1|root,COG1403@2|Bacteria,1GI9P@1117|Cyanobacteria,1HRFK@1161|Nostocales 1117|Cyanobacteria L HNH nucleases - - - - - - - - - - - - HNH k59_9126_2 234621.RER_25240 4.41e-17 79.3 2DYV8@1|root,32V63@2|Bacteria,2GRK5@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_92110_1 439497.RR11_545 3.67e-21 97.4 COG1922@1|root,COG2148@1|root,COG1922@2|Bacteria,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,2U7DN@28211|Alphaproteobacteria,4NC2K@97050|Ruegeria 28211|Alphaproteobacteria M hmm pf02397 - - - - - - - - - - - - Bac_transf,CoA_binding_3,Glyco_tran_WecB k59_141905_2 1385658.U5KNR1_9VIRU 2.87e-21 93.2 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_75519_3 1379709.S5TMV0_9CIRC 5.28e-21 98.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_208343_1 563192.HMPREF0179_03457 8.88e-49 176.0 COG0749@1|root,COG0749@2|Bacteria,1P27P@1224|Proteobacteria,42YUP@68525|delta/epsilon subdivisions,2WTS1@28221|Deltaproteobacteria,2MAPB@213115|Desulfovibrionales 28221|Deltaproteobacteria L DNA polymerase A domain - - - - - - - - - - - - DNA_pol_A k59_34512_1 1122137.AQXF01000002_gene208 3.41e-18 82.0 2E645@1|root,330T3@2|Bacteria,1NEGX@1224|Proteobacteria,2UJTA@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Holin of 3TMs, for gene-transfer release - - - - - - - - - - - - GTA_holin_3TM k59_34512_4 1509405.GV67_04245 2.5e-24 97.8 COG3023@1|root,COG3023@2|Bacteria,1N032@1224|Proteobacteria,2U6P9@28211|Alphaproteobacteria,4BHDN@82115|Rhizobiaceae 28211|Alphaproteobacteria V N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - Amidase_2,PG_binding_1 k59_100810_1 1429768.W6ART0_9CAUD 1.4e-12 72.8 4QHHT@10239|Viruses,4QZJH@35237|dsDNA viruses no RNA stage,4QTJU@28883|Caudovirales,4QJPT@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_150745_1 1417599.U6C6F9_9CAUD 8.05e-65 211.0 4QBD3@10239|Viruses,4QXFU@35237|dsDNA viruses no RNA stage,4QQ7Z@28883|Caudovirales,4QNJ0@10744|Podoviridae 10744|Podoviridae S P22 coat protein - gene protein 5 - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0008150,GO:0009987,GO:0016032,GO:0016043,GO:0019012,GO:0019028,GO:0019030,GO:0019058,GO:0019068,GO:0019069,GO:0019075,GO:0022607,GO:0039620,GO:0042802,GO:0042803,GO:0044085,GO:0044403,GO:0044419,GO:0044423,GO:0046729,GO:0046797,GO:0046983,GO:0051704,GO:0071840 - - - - - - - - - - - k59_26448_1 742767.HMPREF9456_03337 7.54e-34 132.0 COG5410@1|root,COG5410@2|Bacteria,4NN30@976|Bacteroidetes,2FM53@200643|Bacteroidia,230ZQ@171551|Porphyromonadaceae 976|Bacteroidetes S domain protein - - - - - - - - - - - - - k59_51162_2 1609634.A0A0C5AFV4_9VIRU 2.49e-68 235.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_17610_1 1611039.A0A0C5C3Z3_9CIRC 1.77e-45 164.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_59289_1 1406786.U5PZF6_9CAUD 3.12e-60 219.0 4QG2D@10239|Viruses,4QY76@35237|dsDNA viruses no RNA stage,4QSXU@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_109054_1 592316.Pat9b_2114 1.34e-13 82.8 COG1511@1|root,COG1511@2|Bacteria,1QWV3@1224|Proteobacteria,1T4UM@1236|Gammaproteobacteria 1236|Gammaproteobacteria S tail tape measure protein - - - - - - - - - - - - - k59_109054_3 1548905.A0A0A1IVS4_9CAUD 2.71e-53 184.0 4QH9I@10239|Viruses,4QTW6@28883|Caudovirales,4QMZW@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_241736_1 1429794.A0A0A0Q0K7_9CAUD 8.53e-23 102.0 4QCM7@10239|Viruses,4QVN1@35237|dsDNA viruses no RNA stage,4QPQ5@28883|Caudovirales,4QIHM@10662|Myoviridae 10662|Myoviridae S RNA ligase - - - - - - - - - - - - - k59_159154_1 1475143.W8SNN0_9CIRC 2.94e-22 100.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_134824_2 1336243.JAEA01000002_gene2650 1.16e-18 78.6 COG0209@1|root,COG0209@2|Bacteria,1N0E3@1224|Proteobacteria,2UQM4@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Ribonucleotide reductase, barrel domain - - 1.1.98.6 ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000 - - - Ribonuc_red_lgC k59_10012_1 1298858.AUEL01000029_gene80 5.19e-15 79.7 2C2IA@1|root,2ZW5P@2|Bacteria,1PB15@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_43603_1 1144342.PMI40_01693 1.07e-47 166.0 2C377@1|root,2Z7II@2|Bacteria,1NNYY@1224|Proteobacteria,2VP6Q@28216|Betaproteobacteria 28216|Betaproteobacteria S P22 coat protein - gene protein 5 - - - - - - - - - - - - P22_CoatProtein k59_118439_1 1609634.A0A0C5AFV4_9VIRU 2.86e-72 237.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_118439_3 1165094.RINTHH_3920 5.29e-15 76.6 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_226013_1 1538804.A0A088FAR2_9CAUD 5.27e-37 152.0 4QAQ9@10239|Viruses,4QPTV@28883|Caudovirales,4QKRS@10699|Siphoviridae 10699|Siphoviridae S Putative phage tail protein - GO:0005575,GO:0008150,GO:0016032,GO:0018995,GO:0019012,GO:0019058,GO:0019062,GO:0022610,GO:0030430,GO:0033643,GO:0033646,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044403,GO:0044406,GO:0044419,GO:0044650,GO:0051704 - - - - - - - - - - - k59_226013_2 202954.BBNK01000004_gene2057 1.14e-13 65.9 2BM2S@1|root,32FJW@2|Bacteria,1Q0N0@1224|Proteobacteria,1T788@1236|Gammaproteobacteria,3NS9E@468|Moraxellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_226013_3 335283.Neut_1457 3.49e-22 88.2 2CJX7@1|root,32W32@2|Bacteria,1N82M@1224|Proteobacteria,2VY34@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_226013_4 1548905.A0A0A1IX16_9CAUD 1.87e-74 235.0 4QBTT@10239|Viruses,4QQUU@28883|Caudovirales,4QKWB@10699|Siphoviridae 10699|Siphoviridae S Phage conserved hypothetical protein BR0599 - - - - - - - - - - - - - k59_226013_5 1548905.A0A0A1IV72_9CAUD 1.68e-17 89.7 4QBQM@10239|Viruses,4QPZ5@28883|Caudovirales,4QMBJ@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_76676_10 408672.NBCG_03489 5.91e-61 209.0 COG3227@1|root,COG3227@2|Bacteria,2GJEW@201174|Actinobacteria,4DPG1@85009|Propionibacteriales 201174|Actinobacteria E Thermolysin metallopeptidase, catalytic domain prt1 - - - - - - - - - - - Peptidase_M4,Peptidase_M4_C k59_76676_15 215803.DB30_1125 4.93e-18 97.4 COG1409@1|root,COG1409@2|Bacteria,1N2UT@1224|Proteobacteria,4376F@68525|delta/epsilon subdivisions,2X3M9@28221|Deltaproteobacteria,2YWHB@29|Myxococcales 28221|Deltaproteobacteria S Iron/zinc purple acid phosphatase-like protein C - - - - - - - - - - - - F5_F8_type_C,Metallophos,Metallophos_C k59_10080_3 1732201.A0A0N9N7I3_9CIRC 6.88e-11 68.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_93328_3 317619.ANKN01000190_gene578 8.31e-52 174.0 COG3772@1|root,COG3772@2|Bacteria 2|Bacteria S cytolysis by virus of host cell - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Glyco_hydro_19,Phage_lysozyme k59_226374_2 938293.CAJU020000016_gene1794 1.97e-12 68.2 COG3935@1|root,COG3935@2|Bacteria,1TPPF@1239|Firmicutes,249NG@186801|Clostridia,22I2B@1570339|Peptoniphilaceae 186801|Clostridia L Psort location Cytoplasmic, score - - - - - - - - - - - - DnaB_2,HTH_36 k59_118949_2 1197951.I6S6K3_9CAUD 3.44e-10 62.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales 28883|Caudovirales S N-acetylmuramoyl-L-alanine amidase activity - - - - - - - - - - - - - k59_250693_1 1042209.HK44_029960 3.93e-53 199.0 2D1GK@1|root,32TAP@2|Bacteria,1QV4T@1224|Proteobacteria,1SKJY@1236|Gammaproteobacteria 1236|Gammaproteobacteria L C-5 cytosine-specific DNA methylase - - - - - - - - - - - - DNA_methylase k59_143649_1 1562076.A0A0A0YSJ5_9CAUD 5.41e-06 55.8 4QAKM@10239|Viruses,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_192568_3 1609634.A0A0C5AFV4_9VIRU 2.08e-123 372.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_10397_1 1114964.L485_01010 3.41e-59 225.0 2DBPZ@1|root,2ZABJ@2|Bacteria,1R7CU@1224|Proteobacteria,2UEX4@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_84848_1 438753.AZC_0840 1.37e-13 77.0 COG3170@1|root,COG3170@2|Bacteria,1R69E@1224|Proteobacteria,2U3B9@28211|Alphaproteobacteria 28211|Alphaproteobacteria NU Phage P22-like portal protein - - - - - - - - - - - - - k59_119079_1 1165094.RINTHH_3920 6.72e-30 117.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_43939_1 563192.HMPREF0179_02946 0.000104 45.8 2DNTW@1|root,32Z46@2|Bacteria,1N82R@1224|Proteobacteria,431IC@68525|delta/epsilon subdivisions,2WWYT@28221|Deltaproteobacteria,2MDJ5@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_176360_1 688270.Celal_2278 1.99e-09 68.2 COG1511@1|root,COG3210@1|root,COG5295@1|root,COG1511@2|Bacteria,COG3210@2|Bacteria,COG5295@2|Bacteria,4NPY0@976|Bacteroidetes,1I50Q@117743|Flavobacteriia,1F8SR@104264|Cellulophaga 976|Bacteroidetes U Hep Hag repeat protein - - - - - - - - - - - - - k59_234137_2 1168065.DOK_16928 1.43e-26 106.0 COG3926@1|root,COG3926@2|Bacteria,1MVXW@1224|Proteobacteria,1RRB6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S secretion activating protein - - - - - - - - - - - - Glyco_hydro_108,PG_binding_3 k59_260097_1 1692244.A0A0K1RLR5_9CIRC 2.49e-43 151.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_234417_3 765910.MARPU_05835 2.37e-32 124.0 COG2110@1|root,COG2110@2|Bacteria,1MVYN@1224|Proteobacteria,1RNHW@1236|Gammaproteobacteria,1WXBX@135613|Chromatiales 135613|Chromatiales S PFAM Appr-1-p processing domain protein - - - - - - - - - - - - Macro k59_192984_3 42565.FP66_04595 4.09e-07 51.2 2ER6M@1|root,33IS8@2|Bacteria,1NIM1@1224|Proteobacteria,1SU18@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_192984_4 1279019.ARQK01000045_gene517 2.44e-177 542.0 COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,1R97W@1224|Proteobacteria,1TK9M@1236|Gammaproteobacteria,1X0PG@135613|Chromatiales 135613|Chromatiales D Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_192984_6 1232410.KI421417_gene2767 2.15e-43 159.0 29UKS@1|root,30FY7@2|Bacteria,1RGKW@1224|Proteobacteria,430C2@68525|delta/epsilon subdivisions,2WW6K@28221|Deltaproteobacteria 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_127613_1 742738.HMPREF9460_04053 9.98e-65 207.0 COG0270@1|root,COG0270@2|Bacteria,1TPNE@1239|Firmicutes,24B1A@186801|Clostridia,26A94@186813|unclassified Clostridiales 186801|Clostridia L C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_168948_2 696748.ASU2_06645 8.6e-05 50.8 COG5295@1|root,COG5295@2|Bacteria,1N338@1224|Proteobacteria,1RPXV@1236|Gammaproteobacteria,1Y7F2@135625|Pasteurellales 135625|Pasteurellales UW autotransporter adhesin - - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - ESPR,YadA_anchor,YadA_head,YadA_stalk k59_93763_1 1122599.AUGR01000009_gene2459 2.07e-63 216.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,1RQUR@1236|Gammaproteobacteria,1XIN6@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen - - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN k59_44365_1 1121441.AUCX01000014_gene507 5.19e-23 104.0 COG5563@1|root,COG5563@2|Bacteria,1Q0JE@1224|Proteobacteria,430IH@68525|delta/epsilon subdivisions,2X0GF@28221|Deltaproteobacteria,2MD65@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_135674_2 1234880.K0A2H8_9CIRC 2.57e-13 73.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_251118_1 1288083.AUKR01000024_gene3453 2.25e-16 83.6 COG0863@1|root,COG0863@2|Bacteria 2|Bacteria L N-4 methylation of cytosine - - 2.1.1.72 ko:K00571,ko:K07319 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_219152_1 691965.D4P7D6_9CAUD 4.44e-36 140.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_219152_2 428125.CLOLEP_01413 5.78e-34 120.0 2E2Y0@1|root,32XYV@2|Bacteria,1VD9S@1239|Firmicutes,24PK0@186801|Clostridia,3WPDR@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_219152_4 411460.RUMTOR_01342 1.08e-53 175.0 28NM4@1|root,2ZBMQ@2|Bacteria,1V1QD@1239|Firmicutes,24G1B@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_102323_5 46681.XP_001738227.1 3.18e-29 123.0 2CSEE@1|root,2RBK2@2759|Eukaryota,3X9MH@554915|Amoebozoa 554915|Amoebozoa G RNA helicase - - - - - - - - - - - - RNA_helicase k59_135679_1 913865.DOT_2883 0.000616 47.8 COG5301@1|root,COG5301@2|Bacteria,1UW80@1239|Firmicutes,24WF3@186801|Clostridia,266CV@186807|Peptococcaceae 186801|Clostridia G exo-alpha-(2->6)-sialidase activity - - - - - - - - - - - - - k59_36143_1 349102.Rsph17025_1819 7.76e-14 74.3 2C2XN@1|root,32GT6@2|Bacteria,1REZE@1224|Proteobacteria,2U8HW@28211|Alphaproteobacteria 28211|Alphaproteobacteria S PFAM ERF family protein - - - - - - - - - - - - ERF k59_144787_1 1028800.RG540_CH13710 1.02e-45 166.0 COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1QT52@1224|Proteobacteria,2TVNI@28211|Alphaproteobacteria,4BIA7@82115|Rhizobiaceae 28211|Alphaproteobacteria L Toprim-like - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - DnaB_C,Toprim_2 k59_102672_1 765869.BDW_05800 2.9e-08 62.8 COG3209@1|root,COG3210@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,1NED3@1224|Proteobacteria,42WDX@68525|delta/epsilon subdivisions,2MTVC@213481|Bdellovibrionales,2WRDH@28221|Deltaproteobacteria 213481|Bdellovibrionales U cell wall surface anchor family protein - - - - - - - - - - - - Peptidase_S74 k59_169435_1 1410628.JNKS01000008_gene3430 3.09e-22 95.9 COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,2498Z@186801|Clostridia,27MYW@186928|unclassified Lachnospiraceae 186801|Clostridia L RadC-like JAB domain radC - - ko:K03630 - - - - ko00000 - - - RadC k59_69481_1 986075.CathTA2_0705 1.07e-35 139.0 COG5280@1|root,COG5412@1|root,COG5280@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,4HAFE@91061|Bacilli 91061|Bacilli M Phage tail tape measure protein - - - - - - - - - - - - Peptidase_M23,PhageMin_Tail,SLT k59_85413_1 762982.HMPREF9442_01222 1.96e-41 147.0 COG0863@1|root,COG0863@2|Bacteria,4NQQ1@976|Bacteroidetes 976|Bacteroidetes L DNA methylase - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_36150_2 66284.S5FXL2_BPSF2 3.52e-116 352.0 4QBV3@10239|Viruses,4QW0W@35237|dsDNA viruses no RNA stage,4QPPJ@28883|Caudovirales 28883|Caudovirales S Phage Terminase - - - - - - - - - - - - - k59_193404_1 1609634.A0A0C5AFT2_9VIRU 2.38e-36 132.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_11095_1 264732.Moth_1137 2.14e-28 119.0 COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,249EN@186801|Clostridia,42F6G@68295|Thermoanaerobacterales 186801|Clostridia F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrdJ - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Intein_splicing,LAGLIDADG_3,Ribonuc_red_2_N,Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD k59_94077_1 1122201.AUAZ01000017_gene2947 2.31e-117 365.0 COG0749@1|root,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,465DD@72275|Alteromonadaceae 1236|Gammaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity - - - - - - - - - - - - DNA_pol_A k59_78030_1 1476390.A0A060RIN6_9CAUD 3.53e-13 74.3 4QB5N@10239|Viruses,4R0DQ@35237|dsDNA viruses no RNA stage,4QUH8@28883|Caudovirales,4QMVX@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_78030_2 1192868.CAIU01000008_gene924 1.49e-141 409.0 COG5492@1|root,COG5492@2|Bacteria,1R69J@1224|Proteobacteria,2UA50@28211|Alphaproteobacteria 28211|Alphaproteobacteria N domain, Protein - - - - - - - - - - - - - k59_260660_3 1540095.A0A0A0YP73_9CAUD 1.15e-12 70.5 4QAVB@10239|Viruses,4QPIJ@28883|Caudovirales,4QI48@10662|Myoviridae 10662|Myoviridae S defense response to bacterium - - - - - - - - - - - - - k59_45136_2 1028800.RG540_CH13650 1.43e-53 172.0 2E0FP@1|root,300A6@2|Bacteria,1PQHQ@1224|Proteobacteria,2V2WQ@28211|Alphaproteobacteria,4BJS5@82115|Rhizobiaceae 28211|Alphaproteobacteria L Phage endonuclease I - - - - - - - - - - - - Phage_endo_I k59_45136_3 411476.BACOVA_01530 3.72e-21 97.4 COG3023@1|root,COG3023@2|Bacteria,4P4CH@976|Bacteroidetes,2FRT5@200643|Bacteroidia,4AQU8@815|Bacteroidaceae 976|Bacteroidetes V N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - Amidase_2 k59_45136_4 420324.KI911970_gene1435 5.26e-23 93.6 2ETHG@1|root,33M1D@2|Bacteria,1NPDI@1224|Proteobacteria,2UNE7@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Helix-turn-helix domain - - - - - - - - - - - - HTH_39 k59_45136_6 1028800.RG540_CH13710 1.89e-208 597.0 COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1QT52@1224|Proteobacteria,2TVNI@28211|Alphaproteobacteria,4BIA7@82115|Rhizobiaceae 28211|Alphaproteobacteria L Toprim-like - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - DnaB_C,Toprim_2 k59_45136_7 563192.HMPREF0179_03457 1.92e-123 389.0 COG0749@1|root,COG0749@2|Bacteria,1P27P@1224|Proteobacteria,42YUP@68525|delta/epsilon subdivisions,2WTS1@28221|Deltaproteobacteria,2MAPB@213115|Desulfovibrionales 28221|Deltaproteobacteria L DNA polymerase A domain - - - - - - - - - - - - DNA_pol_A k59_45136_8 136084.Q9G0H4_9CAUD 2.6e-66 211.0 4QAUS@10239|Viruses,4QURX@35237|dsDNA viruses no RNA stage,4QQ2S@28883|Caudovirales,4QNNP@10744|Podoviridae 10744|Podoviridae S flavin adenine dinucleotide binding - - - - - - - - - - - - - k59_45136_10 1028800.RG540_CH13770 1e-88 271.0 COG0258@1|root,COG0258@2|Bacteria,1MYSI@1224|Proteobacteria,2U60N@28211|Alphaproteobacteria,4BJMF@82115|Rhizobiaceae 28211|Alphaproteobacteria L 5'-3' exonuclease, N-terminal resolvase-like domain - - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc_N k59_45136_11 398578.Daci_3225 0.000161 45.4 2EI4V@1|root,33BW7@2|Bacteria,1NN3Z@1224|Proteobacteria 1224|Proteobacteria S Protein of unknwon function (DUF3310) - - - - - - - - - - - - DUF3310 k59_45136_12 1336243.JAEA01000002_gene2654 2.11e-22 94.4 COG4696@1|root,COG4696@2|Bacteria,1NMJC@1224|Proteobacteria,2VGV1@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - - k59_45136_13 1197951.I6R0Z3_9CAUD 0.0 997.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales 28883|Caudovirales S Ribonucleotide reductase, barrel domain - GO:0003674,GO:0003824,GO:0004748,GO:0008150,GO:0008152,GO:0016491,GO:0016725,GO:0016728,GO:0055114,GO:0061731 - - - - - - - - - - - k59_28837_2 1211777.BN77_4169 1.66e-126 377.0 2C5GI@1|root,2Z8C1@2|Bacteria,1R8XM@1224|Proteobacteria,2TUME@28211|Alphaproteobacteria,4BJKS@82115|Rhizobiaceae 28211|Alphaproteobacteria S P22 coat protein - gene protein 5 - - - - - - - - - - - - P22_CoatProtein k59_78234_1 1229205.BUPH_03805 7.46e-60 203.0 28HEE@1|root,2Z7QU@2|Bacteria,1MXU6@1224|Proteobacteria,2VISI@28216|Betaproteobacteria,1K35U@119060|Burkholderiaceae 28216|Betaproteobacteria S Domain of unknown function (DUF932) - - - - - - - - - - - - DUF932 k59_45140_1 339671.Asuc_1218 8.19e-06 46.2 2EJST@1|root,33DHF@2|Bacteria,1QI8X@1224|Proteobacteria,1TG32@1236|Gammaproteobacteria,1YAP9@135625|Pasteurellales 135625|Pasteurellales S Helix-turn-helix domain - - - - - - - - - - - - HTH_39 k59_169755_2 391937.NA2_19953 2.25e-08 58.5 COG1846@1|root,COG1846@2|Bacteria,1QZVB@1224|Proteobacteria 1224|Proteobacteria K Helix-turn-helix domain - - - - - - - - - - - - HTH_36 k59_69853_1 1609634.A0A0C5AFT2_9VIRU 1.6e-71 228.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_153325_1 438753.AZC_3598 2.96e-63 211.0 COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1QT52@1224|Proteobacteria,2TVNI@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Toprim-like - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - DnaB_C,Toprim_2 k59_28948_4 411901.BACCAC_00254 3.08e-07 60.5 COG3420@1|root,COG3420@2|Bacteria,4NK37@976|Bacteroidetes 976|Bacteroidetes P Right handed beta helix region - - - - - - - - - - - - Beta_helix k59_260984_1 857087.Metme_2336 2.71e-113 341.0 2CI0W@1|root,2Z81W@2|Bacteria,1R9FZ@1224|Proteobacteria,1S0NA@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage X family - - - - - - - - - - - - Phage_CRI,Phage_X k59_220560_1 1122214.AQWH01000008_gene1569 5.87e-07 58.5 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2TRJF@28211|Alphaproteobacteria,2PJ5A@255475|Aurantimonadaceae 28211|Alphaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_170155_1 1121035.AUCH01000009_gene951 0.00024 49.3 COG4128@1|root,COG4128@2|Bacteria,1RBNK@1224|Proteobacteria,2VSAE@28216|Betaproteobacteria 28216|Betaproteobacteria S occludens toxin - - - ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko02042 - - - Zot k59_252054_2 509635.N824_24725 6.51e-43 153.0 COG5526@1|root,COG5526@2|Bacteria,4P28W@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - k59_4628_1 1123247.AUIJ01000008_gene2652 2.55e-89 287.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2TS19@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdZ - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_lgC,Ribonuc_red_lgN k59_45595_2 933262.AXAM01000111_gene2439 2.77e-26 104.0 COG1192@1|root,COG1192@2|Bacteria,1RFUN@1224|Proteobacteria,42RTS@68525|delta/epsilon subdivisions,2WNDF@28221|Deltaproteobacteria,2MJSU@213118|Desulfobacterales 28221|Deltaproteobacteria D 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family - - - - - - - - - - - - AAA_31 k59_228014_3 889338.G3BLN0_9CAUD 4.47e-15 79.0 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales,4QI6J@10662|Myoviridae 10662|Myoviridae S sequence-specific DNA binding transcription factor activity - - - - - - - - - - - - - k59_252161_1 1122135.KB893141_gene84 8.2e-23 94.7 COG2131@1|root,COG2131@2|Bacteria,1RD1P@1224|Proteobacteria,2UD7X@28211|Alphaproteobacteria 28211|Alphaproteobacteria F COG2131 Deoxycytidylate deaminase - - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 k59_220704_2 1082932.ATCR1_06746 3.7e-38 150.0 COG2268@1|root,COG2268@2|Bacteria,1NT13@1224|Proteobacteria,2U335@28211|Alphaproteobacteria,4BCZZ@82115|Rhizobiaceae 28211|Alphaproteobacteria S Band 7 protein - - - - - - - - - - - - - k59_19878_3 630626.EBL_c21840 1.63e-30 117.0 2D0K9@1|root,32T8S@2|Bacteria,1MZRW@1224|Proteobacteria,1SF0N@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_19878_5 1124991.MU9_2905 2.04e-180 533.0 COG5565@1|root,COG5565@2|Bacteria,1R6R3@1224|Proteobacteria,1RY0J@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C k59_112327_1 2003327.CAPSD_BPCHP 8.48e-58 202.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_112327_2 115711.CP_0543 2.36e-13 68.9 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_12009_1 1395513.P343_07975 4.14e-20 94.0 28JC4@1|root,2Z96S@2|Bacteria,1TS1K@1239|Firmicutes,4HDVZ@91061|Bacilli,26PTU@186821|Sporolactobacillaceae 91061|Bacilli S P22 coat protein-protein 5 domain protein - - - - - - - - - - - - P22_CoatProtein k59_186523_1 1122176.KB903533_gene2285 4.69e-74 233.0 COG4227@1|root,COG4227@2|Bacteria,4NM80@976|Bacteroidetes,1IUPC@117747|Sphingobacteriia 976|Bacteroidetes L Domain of unknown function (DUF1738) - - - - - - - - - - - - DUF1738,MutS_I k59_261394_1 1173709.M3VMK9_9CIRC 1.88e-32 123.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_70396_2 1986029.Q9MBM8_9VIRU 1.21e-10 60.8 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_78765_2 1379717.S5SY19_9CIRC 7.43e-71 228.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_178276_1 1348583.ATLH01000006_gene1103 0.000133 50.1 COG3391@1|root,COG3391@2|Bacteria,4PKUJ@976|Bacteroidetes,1IJFM@117743|Flavobacteriia,1F876@104264|Cellulophaga 976|Bacteroidetes S C-terminal domain of CHU protein family - - - - - - - - - - - - CHU_C,PKD k59_86217_1 596151.DesfrDRAFT_2482 1.49e-31 132.0 COG0358@1|root,COG4643@1|root,COG0358@2|Bacteria,COG4643@2|Bacteria,1QV6T@1224|Proteobacteria,43BNT@68525|delta/epsilon subdivisions,2X8DB@28221|Deltaproteobacteria,2MHGM@213115|Desulfovibrionales 28221|Deltaproteobacteria L Toprim domain - - - - - - - - - - - - Toprim_3 k59_186604_1 205918.Psyr_2827 4.25e-36 136.0 COG0175@1|root,COG0175@2|Bacteria,1PZ96@1224|Proteobacteria,1SBUC@1236|Gammaproteobacteria 1236|Gammaproteobacteria EH Phosphoadenosine phosphosulfate reductase family - - - - - - - - - - - - PAPS_reduct k59_94913_2 64471.sync_0038 1.1e-15 79.3 COG0553@1|root,COG0553@2|Bacteria,1GBFC@1117|Cyanobacteria,1GYR9@1129|Synechococcus 1117|Cyanobacteria KL Superfamily II DNA RNA helicases, SNF2 family - - - - - - - - - - - - Helicase_C,SNF2_N k59_129311_1 49964.Q94MS1_9CAUD 6.23e-72 226.0 4QB4H@10239|Viruses,4QYQI@35237|dsDNA viruses no RNA stage,4QUAR@28883|Caudovirales,4QNUV@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_20053_7 384360.A0JC21_9VIRU 1.2e-20 99.8 4QBCQ@10239|Viruses,4QUMB@29258|ssDNA viruses,4QP4S@10860|Inoviridae 10860|Inoviridae S DNA topoisomerase activity - - - - - - - - - - - - - k59_112414_1 5786.XP_003292844.1 1.55e-05 52.8 COG0553@1|root,KOG1000@2759|Eukaryota,3XFTR@554915|Amoebozoa 554915|Amoebozoa L annealing helicase activity - - - - - - - - - - - - - k59_261468_1 1408444.JHYC01000008_gene1375 7.86e-44 155.0 COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,1RMCS@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Belongs to the DegT DnrJ EryC1 family - - - - - - - - - - - - DegT_DnrJ_EryC1 k59_146278_2 479434.Sthe_2063 9.43e-05 50.1 COG1573@1|root,COG1573@2|Bacteria,2G8Q5@200795|Chloroflexi 200795|Chloroflexi L Uracil DNA glycosylase superfamily - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k59_235844_1 1235788.C802_00061 4.67e-09 58.5 COG0270@1|root,COG0270@2|Bacteria,4NVMZ@976|Bacteroidetes 976|Bacteroidetes L C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_46324_1 342949.PNA2_0859 0.000155 53.1 COG0417@1|root,arCOG00328@2157|Archaea,2XU1K@28890|Euryarchaeota,242Z2@183968|Thermococci 183968|Thermococci L DNA polymerase pol - 2.7.7.7 ko:K02319 ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032 - - - DNA_pol_B,DNA_pol_B_exo1,Intein_splicing,LAGLIDADG_3 k59_261820_1 1123368.AUIS01000027_gene1355 3.58e-23 105.0 COG2192@1|root,COG2192@2|Bacteria,1MWBA@1224|Proteobacteria,1RNN4@1236|Gammaproteobacteria 1236|Gammaproteobacteria O carbamoyl transferase, NodU family - - - ko:K00612 - - - - ko00000,ko01000 - - - Carbam_trans_C,Carbam_trans_N k59_146382_1 1114179.I2FLT8_9CAUD 7.16e-38 150.0 4QAUF@10239|Viruses,4QWIQ@35237|dsDNA viruses no RNA stage,4QUFS@28883|Caudovirales,4QNVK@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_37330_2 1498011.A0A096XUU5_9CAUD 1.63e-78 252.0 4QAUT@10239|Viruses,4QQ7X@28883|Caudovirales,4QNET@10744|Podoviridae 10744|Podoviridae S DNA ligase (ATP) activity - - - - - - - - - - - - - k59_137512_1 1592107.A0A0B4UHX2_9VIRU 9.97e-55 184.0 4QB6C@10239|Viruses 10239|Viruses L Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_54621_2 428125.CLOLEP_01413 2.53e-26 103.0 2E2Y0@1|root,32XYV@2|Bacteria,1VD9S@1239|Firmicutes,24PK0@186801|Clostridia,3WPDR@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_154242_1 394503.Ccel_3060 2.44e-151 445.0 COG0553@1|root,COG0553@2|Bacteria,1TP2C@1239|Firmicutes,24DVA@186801|Clostridia,36FNM@31979|Clostridiaceae 186801|Clostridia L SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,N6_N4_Mtase,SNF2_N k59_221371_1 1028800.RG540_CH13710 9.59e-33 132.0 COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1QT52@1224|Proteobacteria,2TVNI@28211|Alphaproteobacteria,4BIA7@82115|Rhizobiaceae 28211|Alphaproteobacteria L Toprim-like - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - DnaB_C,Toprim_2 k59_86549_1 713586.KB900537_gene3383 1.42e-33 130.0 2DCM2@1|root,32TZV@2|Bacteria,1NAGE@1224|Proteobacteria,1SMRS@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_121078_1 443254.Marpi_0340 7.05e-17 83.2 COG1408@1|root,COG1408@2|Bacteria,2GDNN@200918|Thermotogae 200918|Thermotogae L metallophosphoesterase - - - - - - - - - - - - - k59_46461_1 1055815.AYYA01000060_gene319 1.64e-59 184.0 COG2963@1|root,COG2963@2|Bacteria,1N1AA@1224|Proteobacteria,1S9QC@1236|Gammaproteobacteria,3NNNJ@468|Moraxellaceae 1236|Gammaproteobacteria L Transposase - - - ko:K07483 - - - - ko00000 - - - HTH_Tnp_1 k59_46461_2 1055815.AYYA01000049_gene1745 4.3e-56 182.0 COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1RSHU@1236|Gammaproteobacteria,3NKQX@468|Moraxellaceae 1236|Gammaproteobacteria L Transposase tnpB - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_3 k59_37336_2 1217715.F994_02465 1.01e-05 50.8 COG1876@1|root,COG1876@2|Bacteria,1MXWT@1224|Proteobacteria,1S6G6@1236|Gammaproteobacteria,3NIZ9@468|Moraxellaceae 1236|Gammaproteobacteria M D-alanyl-D-alanine carboxypeptidase - - - ko:K17733 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M15_4 k59_40038_2 1618248.A0A0C5IB82_9CIRC 1.18e-93 286.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_190717_2 285514.JNWO01000087_gene7172 1.73e-07 59.3 COG0582@1|root,COG0582@2|Bacteria,2I9HX@201174|Actinobacteria 201174|Actinobacteria L Phage integrase family - - - - - - - - - - - - Phage_integrase k59_40039_1 272134.KB731324_gene2720 4.11e-73 240.0 COG1783@1|root,COG4373@1|root,COG1783@2|Bacteria,COG4373@2|Bacteria 2|Bacteria S DNA packaging xtmB - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C,Terminase_6,Terminase_6C k59_231457_1 585502.HMPREF0645_2609 1.73e-207 603.0 COG0553@1|root,COG0863@1|root,COG0553@2|Bacteria,COG0863@2|Bacteria,4NHHF@976|Bacteroidetes,2FRI5@200643|Bacteroidia 976|Bacteroidetes KL DNA methylase - - - - - - - - - - - - Helicase_C,N6_N4_Mtase,SNF2_N k59_132445_1 1609634.A0A0C5AFV4_9VIRU 2.2e-73 239.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_106649_1 880071.Fleli_1691 8.96e-30 122.0 COG0587@1|root,COG0847@1|root,COG1372@1|root,COG0587@2|Bacteria,COG0847@2|Bacteria,COG1372@2|Bacteria,4NFA0@976|Bacteroidetes,47K9H@768503|Cytophagia 976|Bacteroidetes L DNA-directed DNA polymerase dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon k59_124386_1 1123487.KB892865_gene1375 8.86e-176 499.0 28MVD@1|root,2ZB2Y@2|Bacteria,1R8NK@1224|Proteobacteria,2VPRP@28216|Betaproteobacteria,2KZJK@206389|Rhodocyclales 206389|Rhodocyclales S Protein of unknown function (DUF4043) - - - - - - - - - - - - DUF4043 k59_124386_4 1123487.KB892865_gene1372 6.55e-57 187.0 2ECIJ@1|root,336GQ@2|Bacteria,1NFBI@1224|Proteobacteria,2VYFZ@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_124386_12 330084.JNYZ01000003_gene2277 5.52e-22 93.2 2BM0Q@1|root,32FHM@2|Bacteria,2IK53@201174|Actinobacteria,4ECAS@85010|Pseudonocardiales 201174|Actinobacteria - - - - - - - - - - - - - - - k59_247000_1 1540097.A0A0A0YR01_9CAUD 5.39e-09 66.2 4QE55@10239|Viruses,4QSGR@28883|Caudovirales,4QNIB@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_174131_2 1219035.NT2_13_00580 8.14e-24 104.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_15114_1 1385658.U5KPZ6_9VIRU 1.03e-159 467.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_255525_1 1121935.AQXX01000096_gene2520 5.15e-25 105.0 COG4733@1|root,COG4733@2|Bacteria,1MXB4@1224|Proteobacteria,1RRUV@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Putative phage tail protein - - - - - - - - - - - - Phage-tail_3 k59_255525_2 522373.Smlt1855 7.85e-15 68.9 2EK40@1|root,33DUE@2|Bacteria,1NJE0@1224|Proteobacteria,1SUTD@1236|Gammaproteobacteria,1X8XT@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - k59_157080_3 1133849.O3I_003005 1.03e-25 114.0 COG5002@1|root,COG5002@2|Bacteria,2I2DU@201174|Actinobacteria,4FTXC@85025|Nocardiaceae 201174|Actinobacteria T His Kinase A (phosphoacceptor) domain phoR - 2.7.13.3 ko:K02484 - - - - ko00000,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA k59_140840_1 1458716.W8FPY0_9CAUD 1.18e-19 94.4 4QH10@10239|Viruses,4QXEE@35237|dsDNA viruses no RNA stage,4QSY9@28883|Caudovirales,4QNP4@10744|Podoviridae 10744|Podoviridae S Terminase-like family - - - - - - - - - - - - - k59_197745_1 1230469.M5AAF3_9CAUD 1.29e-15 77.0 4QBHW@10239|Viruses,4QW8N@35237|dsDNA viruses no RNA stage,4QTT7@28883|Caudovirales,4QKR7@10699|Siphoviridae 10699|Siphoviridae S sequence-specific DNA binding transcription factor activity - - - - - - - - - - - - - k59_238805_1 439375.Oant_1523 5.3e-13 73.9 2DEFV@1|root,2ZMV1@2|Bacteria,1P428@1224|Proteobacteria,2UY04@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_215533_1 1327974.S0A0U7_9CAUD 1.6e-62 214.0 4QCHV@10239|Viruses,4QUW9@35237|dsDNA viruses no RNA stage,4QQEZ@28883|Caudovirales,4QMEA@10699|Siphoviridae 10699|Siphoviridae S Virulence-associated protein E - - - - - - - - - - - - - k59_248507_2 500637.PROVRUST_07101 7.21e-18 80.1 COG3613@1|root,COG3613@2|Bacteria,1RKNZ@1224|Proteobacteria,1SC8F@1236|Gammaproteobacteria,3Z951@586|Providencia 1236|Gammaproteobacteria F Domain of unknown function (DUF4406) - - - - - - - - - - - - DUF1937 k59_66123_1 1121948.AUAC01000003_gene2894 3.92e-38 135.0 COG3108@1|root,COG3108@2|Bacteria,1NMU6@1224|Proteobacteria,2UJD2@28211|Alphaproteobacteria,43YD7@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Peptidase M15 - - - - - - - - - - - - Peptidase_M15_3 k59_265209_2 759938.F5BSB4_9CIRC 1.87e-30 128.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_265212_2 1618256.A0A0C5IM93_9CIRC 2.85e-21 98.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_90685_1 665956.HMPREF1032_00665 3.95e-41 154.0 28JED@1|root,2Z98K@2|Bacteria,1TW1U@1239|Firmicutes,24CFD@186801|Clostridia,3WNW0@541000|Ruminococcaceae 186801|Clostridia K Bacterial regulatory proteins, luxR family - - - - - - - - - - - - GerE k59_265218_1 1126411.I1TEL3_9CIRC 7.97e-31 124.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_265220_1 1618248.A0A0C5IB82_9CIRC 1.38e-19 94.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_90721_1 436308.Nmar_1073 2.69e-07 58.5 COG3794@1|root,arCOG05978@1|root,arCOG07813@1|root,arCOG02926@2157|Archaea,arCOG05978@2157|Archaea,arCOG07813@2157|Archaea 2157|Archaea C LamG domain protein jellyroll fold domain protein - - 2.7.11.1 ko:K12567 ko05410,ko05414,map05410,map05414 - - - ko00000,ko00001,ko01000,ko01001,ko04131,ko04147,ko04812 - - - Copper-bind,GSDH,Laminin_G_3,ThuA,fn3 k59_90726_1 909943.HIMB100_00023400 7.4e-50 168.0 COG1442@1|root,COG1442@2|Bacteria,1QH4S@1224|Proteobacteria,2U2NZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria M glycosyl transferase family 8 - - - - - - - - - - - - - k59_265227_2 742918.D4N3P2_9CIRC 6.39e-27 115.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_174515_1 1304275.C41B8_05448 1.83e-22 90.9 2D1MV@1|root,32TAZ@2|Bacteria,1N45A@1224|Proteobacteria,1S954@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage protein (N4 Gp49/phage Sf6 gene 66) family - - - - - - - - - - - - DUF2829,Phage_gp49_66 k59_174515_4 317025.Tcr_1554 5.92e-15 82.0 COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,1RMQN@1236|Gammaproteobacteria,460B0@72273|Thiotrichales 72273|Thiotrichales T PFAM PhoH-like protein - - - ko:K07175 - - - - ko00000 - - - PIN_4,PhoH k59_174515_7 627192.SLG_22220 3.15e-16 93.6 COG4733@1|root,COG4733@2|Bacteria,1Q2WW@1224|Proteobacteria,2TUS9@28211|Alphaproteobacteria,2K24W@204457|Sphingomonadales 204457|Sphingomonadales S Phage-related protein, tail component - - - - - - - - - - - - Phage-tail_3 k59_50345_1 298654.FraEuI1c_2225 4.55e-06 55.5 COG1674@1|root,COG1674@2|Bacteria,2GJBR@201174|Actinobacteria 201174|Actinobacteria D DNA segregation ATPase FtsK SpoIIIE and related - - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_SpoIIIE,Yop-YscD_cpl k59_91833_1 1692242.A0A0K1RL37_9CIRC 5.37e-34 126.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_91833_2 1618248.A0A0C5IB82_9CIRC 9.59e-29 112.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_207814_1 182217.HCW_02255 1.58e-21 98.2 COG0863@1|root,COG1092@1|root,COG0863@2|Bacteria,COG1092@2|Bacteria,1NXST@1224|Proteobacteria,42Q3Q@68525|delta/epsilon subdivisions,2YN8U@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_249366_1 948071.S4S2M5_9CAUD 1.64e-43 155.0 4QBD3@10239|Viruses,4QXFU@35237|dsDNA viruses no RNA stage,4QQ7Z@28883|Caudovirales,4QNS1@10744|Podoviridae 10744|Podoviridae S viral capsid - - - - - - - - - - - - - k59_224552_1 1379708.S5SYC3_9CIRC 1.49e-47 165.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_25606_2 596152.DesU5LDRAFT_3296 1.58e-08 61.2 COG0305@1|root,COG0305@2|Bacteria,1PZ6S@1224|Proteobacteria,42YZ3@68525|delta/epsilon subdivisions,2WU0W@28221|Deltaproteobacteria,2MAW9@213115|Desulfovibrionales 28221|Deltaproteobacteria L Toprim-like - - - - - - - - - - - - DnaB_C,Toprim_2 k59_42094_1 1112214.AHIS01000083_gene3635 4.96e-08 62.4 COG4653@1|root,COG4653@2|Bacteria,1MWU1@1224|Proteobacteria,2VF2A@28211|Alphaproteobacteria,2K1Y4@204457|Sphingomonadales 204457|Sphingomonadales S Phage capsid family - - - - - - - - - - - - Phage_capsid k59_42094_2 543728.Vapar_2473 7.1e-08 55.5 COG0740@1|root,COG0740@2|Bacteria,1MUQ9@1224|Proteobacteria,2VPIR@28216|Betaproteobacteria,4AEKF@80864|Comamonadaceae 28216|Betaproteobacteria OU Belongs to the peptidase S14 family - - - - - - - - - - - - CLP_protease k59_75298_1 1498011.A0A096XUS7_9CAUD 4.46e-146 438.0 4QAUF@10239|Viruses,4QQIV@28883|Caudovirales,4QNZ6@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_75298_2 1498011.A0A096XUU0_9CAUD 7.49e-128 376.0 4QG38@10239|Viruses,4QQVI@28883|Caudovirales,4QNWM@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_249374_1 1244083.CSUNSWCD_1478 2.73e-06 52.4 29XS6@1|root,30JHZ@2|Bacteria,1Q8JI@1224|Proteobacteria,431U9@68525|delta/epsilon subdivisions,2YSAT@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria - - - - - - - - - - - - - - - k59_50357_1 1234888.K0A2J2_9VIRU 1.94e-25 109.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_224554_1 1141137.K4F7D5_9CAUD 9.93e-06 56.6 4QAUF@10239|Viruses,4QWIQ@35237|dsDNA viruses no RNA stage,4QUFS@28883|Caudovirales,4QNVK@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_108395_1 1235661.K0IP52_9CAUD 2.49e-20 97.1 4QAUF@10239|Viruses,4QWIQ@35237|dsDNA viruses no RNA stage,4QUFS@28883|Caudovirales,4QNVK@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_125140_1 1618240.A0A0C5IMJ1_9CIRC 2.75e-70 228.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_241167_1 420324.KI911970_gene1460 5.42e-16 89.4 COG5301@1|root,COG5301@2|Bacteria,1N4CW@1224|Proteobacteria,2TYJK@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Phage T7 tail fibre protein - - - - - - - - - - - - Phage_T7_tail k59_150037_1 1028800.RG540_CH13810 9.6e-35 135.0 28MSK@1|root,2ZB0X@2|Bacteria,1R7CY@1224|Proteobacteria,2U2MY@28211|Alphaproteobacteria,4BJ92@82115|Rhizobiaceae 28211|Alphaproteobacteria S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_174591_1 1046714.AMRX01000006_gene3191 1.86e-55 190.0 28JC4@1|root,2Z96S@2|Bacteria,1RI8W@1224|Proteobacteria,1S6FI@1236|Gammaproteobacteria 1236|Gammaproteobacteria S P22 coat protein-protein 5 domain protein - - - - - - - - - - - - - k59_58993_2 1281779.H009_14713 2.09e-59 224.0 28IJ1@1|root,2Z8K0@2|Bacteria,1R5PC@1224|Proteobacteria,2U0RA@28211|Alphaproteobacteria,4BBHX@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_133790_1 105154.Q9MBU6_9VIRU 2.22e-116 351.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_9295_1 349106.PsycPRwf_2393 2.13e-142 429.0 COG1002@1|root,COG1002@2|Bacteria,1MWRH@1224|Proteobacteria,1RRRA@1236|Gammaproteobacteria,3NMQI@468|Moraxellaceae 1236|Gammaproteobacteria V N-6 DNA Methylase - - - - - - - - - - - - N6_Mtase k59_258281_3 1122225.AULQ01000004_gene2180 4.1e-24 95.5 COG1525@1|root,COG1525@2|Bacteria,4NR4U@976|Bacteroidetes,1I3CI@117743|Flavobacteriia 976|Bacteroidetes L Staphylococcal nuclease homologue - - 3.1.31.1 ko:K01174 - - - - ko00000,ko01000 - - - SNase k59_258281_7 1088721.NSU_0331 1.67e-45 150.0 2ECZ3@1|root,336W5@2|Bacteria,1NESK@1224|Proteobacteria,2UI3A@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_26037_2 1526550.A0A088FAT7_9VIRU 1.96e-27 116.0 4QAK6@10239|Viruses 10239|Viruses S N-acetylmuramoyl-L-alanine amidase activity - - - - - - - - - - - - - k59_67410_2 264462.Bd0704 8.39e-11 69.3 COG2911@1|root,COG3209@1|root,COG2911@2|Bacteria,COG3209@2|Bacteria,1QVEQ@1224|Proteobacteria 1224|Proteobacteria M Chaperone of endosialidase - - - - - - - - - - - - Peptidase_S74 k59_1303_1 1173020.Cha6605_2016 3.66e-05 43.9 2ER1H@1|root,33IM1@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_133866_2 4792.ETI31775 2.96e-52 185.0 2C7RP@1|root,2SPXE@2759|Eukaryota 2759|Eukaryota - - - - - - - - - - - - - - - k59_216912_1 1231190.NA8A_23504 1.25e-24 101.0 COG0110@1|root,COG0110@2|Bacteria,1MZV9@1224|Proteobacteria,2V8DI@28211|Alphaproteobacteria,43M7U@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Hexapeptide repeat of succinyl-transferase - - - - - - - - - - - - Hexapep k59_125592_1 1380894.S5TR92_9CIRC 3.48e-33 125.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_125592_2 1380894.S5TR92_9CIRC 5.13e-16 79.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_183481_1 1004785.AMBLS11_12290 6.7e-11 73.2 COG3209@1|root,COG4733@1|root,COG3209@2|Bacteria,COG4733@2|Bacteria,1R7KR@1224|Proteobacteria,1S1E5@1236|Gammaproteobacteria 1236|Gammaproteobacteria D COG4733 Phage-related protein, tail component - - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - DUF1983,Phage-tail_3 k59_225010_1 1429046.RR21198_2324 2.01e-11 74.7 COG0739@1|root,COG0741@1|root,COG0791@1|root,COG0739@2|Bacteria,COG0741@2|Bacteria,COG0791@2|Bacteria,2GP5E@201174|Actinobacteria,4FX1K@85025|Nocardiaceae 201174|Actinobacteria M NlpC/P60 family - - - - - - - - - - - - NLPC_P60,Peptidase_M23,SLT,SLT_2 k59_67954_1 1408418.JNJH01000012_gene3580 2.99e-30 121.0 28N1N@1|root,2ZB7Q@2|Bacteria,1R86T@1224|Proteobacteria,2U0A6@28211|Alphaproteobacteria,2JRMI@204441|Rhodospirillales 204441|Rhodospirillales H Sulfotransferase domain - - - - - - - - - - - - Sulfotransfer_1 k59_183903_1 443143.GM18_2912 7.18e-10 67.0 COG0582@1|root,COG0582@2|Bacteria,1REKP@1224|Proteobacteria,42S9N@68525|delta/epsilon subdivisions,2WNI9@28221|Deltaproteobacteria 28221|Deltaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_integrase k59_200580_1 1618257.A0A0C5IBI9_9CIRC 2.12e-17 82.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_51477_1 411460.RUMTOR_01335 5.52e-24 117.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_167639_1 1147044.H9A0L3_9CAUD 9e-12 68.9 4QBHS@10239|Viruses,4QPT9@28883|Caudovirales 28883|Caudovirales S DNA metabolic process - - - - - - - - - - - - - k59_1955_1 1197951.I6R0Z3_9CAUD 2.27e-17 82.4 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales 28883|Caudovirales S Ribonucleotide reductase, barrel domain - GO:0003674,GO:0003824,GO:0004748,GO:0008150,GO:0008152,GO:0016491,GO:0016725,GO:0016728,GO:0055114,GO:0061731 - - - - - - - - - - - k59_217719_1 446470.Snas_6269 1.02e-12 67.0 COG0863@1|root,COG0863@2|Bacteria,2I9DJ@201174|Actinobacteria 201174|Actinobacteria L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.113,2.1.1.72 ko:K00571,ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_242014_1 145579.H_BPPHM 1.28e-06 54.3 4QCA6@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_101124_1 1120948.KB903243_gene2721 2.2e-15 81.6 COG3266@1|root,COG3266@2|Bacteria,2I302@201174|Actinobacteria,4EF87@85010|Pseudonocardiales 201174|Actinobacteria S response to copper ion - - - - - - - - - - - - Big_5,DUF4082 k59_208741_3 1131814.JAFO01000001_gene2083 1.08e-12 70.1 COG0507@1|root,COG5362@1|root,COG0507@2|Bacteria,COG5362@2|Bacteria,1R90H@1224|Proteobacteria,2U236@28211|Alphaproteobacteria 28211|Alphaproteobacteria L TIGRFAM Phage - - - - - - - - - - - - Terminase_6 k59_26802_1 1385658.U5KNR1_9VIRU 1.95e-35 133.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_26802_3 1609634.A0A0C5AFV4_9VIRU 1.07e-19 88.6 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_151110_1 1465639.A0A060BKV6_9CAUD 2.55e-14 77.8 4QAM2@10239|Viruses,4QV3W@35237|dsDNA viruses no RNA stage,4QPGK@28883|Caudovirales,4QNW0@10744|Podoviridae 10744|Podoviridae S exonuclease activity - GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 - - - - - - - - - - - k59_59574_2 537013.CLOSTMETH_01710 5.03e-10 62.8 2EF3G@1|root,338WJ@2|Bacteria,1VHUW@1239|Firmicutes,24R77@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_84399_2 105154.Q9MBU3_9VIRU 1.29e-18 86.7 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_109402_3 1357423.S5MQB5_9CAUD 9.61e-13 71.6 4QGWX@10239|Viruses,4R0MM@35237|dsDNA viruses no RNA stage,4QQAI@28883|Caudovirales,4QI1A@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_134521_1 446471.Xcel_0522 1.04e-11 73.9 COG4913@1|root,COG5283@1|root,COG4913@2|Bacteria,COG5283@2|Bacteria,2I8JB@201174|Actinobacteria 201174|Actinobacteria D Phage tail tape measure protein, TP901 family - - - - - - - - - - - - PhageMin_Tail k59_142905_1 1618259.A0A0C5I2B5_9CIRC 7.18e-14 73.6 4QE84@10239|Viruses,4QUKR@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_142905_3 1618259.A0A0C5I2B5_9CIRC 4.61e-26 107.0 4QE84@10239|Viruses,4QUKR@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_176455_1 1273125.Rrhod_0983 9.14e-53 176.0 29M5Z@1|root,3083E@2|Bacteria,2IKVT@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_168643_2 537007.BLAHAN_04225 5.6e-32 128.0 COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,1TPHP@1239|Firmicutes,249MR@186801|Clostridia,3XZ5Y@572511|Blautia 186801|Clostridia L Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - N6_N4_Mtase,ParBc k59_209372_1 1123227.KB899344_gene1958 5.21e-06 53.9 COG1216@1|root,COG1216@2|Bacteria,1R554@1224|Proteobacteria,2U3P6@28211|Alphaproteobacteria,2JT5C@204441|Rhodospirillales 204441|Rhodospirillales S Glycosyl transferase, family 2 - - - - - - - - - - - - - k59_201486_1 69279.BG36_07550 6.46e-25 115.0 COG4733@1|root,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria,2TV2W@28211|Alphaproteobacteria 28211|Alphaproteobacteria S COG4733 Phage-related protein, tail component - - - - - - - - - - - - Phage-tail_3 k59_192746_1 95619.PM1_0200065 7.53e-38 132.0 COG1598@1|root,COG1598@2|Bacteria,1N3KE@1224|Proteobacteria,1S32S@1236|Gammaproteobacteria 1236|Gammaproteobacteria K HicB_like antitoxin of bacterial toxin-antitoxin system - - - - - - - - - - - - HicB_lk_antitox k59_60322_2 13690.CP98_03069 1.98e-23 102.0 COG4227@1|root,COG4227@2|Bacteria,1MU8I@1224|Proteobacteria,2TRIT@28211|Alphaproteobacteria,2K1FU@204457|Sphingomonadales 204457|Sphingomonadales L Domain of unknown function (DUF1738) - - - - - - - - - - - - DUF1738 k59_18727_2 205914.HS_p03 2.19e-29 119.0 COG5527@1|root,COG5527@2|Bacteria,1R7A6@1224|Proteobacteria,1RQMU@1236|Gammaproteobacteria,1Y8HW@135625|Pasteurellales 135625|Pasteurellales L Initiator Replication protein - - - - - - - - - - - - Rep_3 k59_52589_1 1232410.KI421417_gene2767 7.21e-24 103.0 29UKS@1|root,30FY7@2|Bacteria,1RGKW@1224|Proteobacteria,430C2@68525|delta/epsilon subdivisions,2WW6K@28221|Deltaproteobacteria 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_218865_1 46681.XP_001738227.1 1.6e-24 102.0 2CSEE@1|root,2RBK2@2759|Eukaryota,3X9MH@554915|Amoebozoa 554915|Amoebozoa G RNA helicase - - - - - - - - - - - - RNA_helicase k59_168738_2 935948.KE386495_gene1350 5.8e-09 56.2 2BX5K@1|root,32R8G@2|Bacteria,1V9DD@1239|Firmicutes 1239|Firmicutes L HNH endonuclease - - - - - - - - - - - - HNH_3 k59_10541_1 1121904.ARBP01000023_gene5016 2.07e-05 51.6 COG2730@1|root,COG5492@1|root,COG2730@2|Bacteria,COG5492@2|Bacteria 2|Bacteria N domain, Protein - - 3.2.1.4 ko:K01179,ko:K03932 ko00500,ko01100,map00500,map01100 - R06200,R11307,R11308 - ko00000,ko00001,ko01000 - CE1,GH5,GH9 - Big_2,Cellulase,Flg_new,SLH k59_192810_2 1444310.JANV01000096_gene3227 2.18e-14 80.5 2EN4Y@1|root,32KKF@2|Bacteria,1UBN5@1239|Firmicutes,4IN2Q@91061|Bacilli,1ZMP2@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k59_218868_1 1126411.I1TEL3_9CIRC 3.5e-09 63.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_27811_2 1618236.A0A0C5IB23_9CIRC 1.79e-18 86.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_102092_1 1452718.JBOY01000021_gene717 4.44e-25 105.0 2DKZ2@1|root,32UFZ@2|Bacteria,1N5GS@1224|Proteobacteria,1SP03@1236|Gammaproteobacteria 1236|Gammaproteobacteria S PD-(D/E)XK nuclease superfamily - - - - - - - - - - - - PDDEXK_1 k59_78046_1 2003327.CAPSD_BPCHP 1.26e-30 127.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_202381_1 1618236.A0A0C5IB23_9CIRC 1.8e-07 57.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_3908_1 1692250.A0A0K1RLR1_9CIRC 5.62e-22 97.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_128226_1 1234888.K0A2J2_9VIRU 4.01e-52 183.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_153026_2 1121123.AUAO01000004_gene1662 1.72e-27 106.0 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,2U5BZ@28211|Alphaproteobacteria,2KGA6@204458|Caulobacterales 204458|Caulobacterales L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_153026_4 1408428.JNJP01000010_gene1294 1.14e-29 125.0 COG4227@1|root,COG4643@1|root,COG4227@2|Bacteria,COG4643@2|Bacteria,1MU8I@1224|Proteobacteria,42N43@68525|delta/epsilon subdivisions,2WM7N@28221|Deltaproteobacteria,2M823@213115|Desulfovibrionales 28221|Deltaproteobacteria L Domain of unknown function (DUF1738) - - - - - - - - - - - - DUF1738,Toprim_3 k59_153026_6 314231.FP2506_00470 2.56e-16 82.4 COG1475@1|root,COG1475@2|Bacteria,1MVF9@1224|Proteobacteria,2TR0P@28211|Alphaproteobacteria,2PJQC@255475|Aurantimonadaceae 28211|Alphaproteobacteria K ParB domain protein nuclease - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_234847_1 461711.A0A096VKW7_9CAUD 2.07e-28 107.0 4QASP@10239|Viruses,4QVR8@35237|dsDNA viruses no RNA stage,4QR4Z@28883|Caudovirales,4QNQ0@10744|Podoviridae 10744|Podoviridae S deoxyribonuclease IV (phage-T4-induced) activity - - - - - - - - - - - - - k59_234847_4 1340826.S5Y506_9CAUD 1.94e-24 102.0 4QARC@10239|Viruses,4QV4E@35237|dsDNA viruses no RNA stage,4QPDS@28883|Caudovirales,4QKXX@10699|Siphoviridae 10699|Siphoviridae S RNase_H superfamily - - - - - - - - - - - - - k59_111446_1 926560.KE387023_gene1950 2.38e-10 65.5 COG3864@1|root,COG3864@2|Bacteria,1WME0@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S Putative metallopeptidase domain - - - - - - - - - - - - DUF2201,DUF2201_N k59_11227_1 1618248.A0A0C5IB82_9CIRC 1.28e-44 157.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_11227_3 1618248.A0A0C5IB82_9CIRC 1.47e-34 127.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_28661_1 1219035.NT2_13_00580 1e-20 93.6 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_28661_6 1219035.NT2_13_00580 1.68e-08 59.3 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_94174_2 1219035.NT2_13_00580 1.6e-54 190.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_202383_1 742740.HMPREF9474_02303 2.38e-84 285.0 2EWZQ@1|root,33QB0@2|Bacteria,1V0T1@1239|Firmicutes,249Z2@186801|Clostridia,221YV@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_185686_1 1449351.RISW2_18815 5.09e-16 85.5 COG3064@1|root,COG3772@1|root,COG5283@1|root,COG3064@2|Bacteria,COG3772@2|Bacteria,COG5283@2|Bacteria,1NFKU@1224|Proteobacteria,2U1H4@28211|Alphaproteobacteria,4KNPX@93682|Roseivivax 28211|Alphaproteobacteria G Phage-related minor tail protein - - - - - - - - - - - - Peptidase_M15_3,PhageMin_Tail k59_260678_1 189753.AXAS01000033_gene2910 4.28e-17 87.8 COG4974@1|root,COG4974@2|Bacteria,1MXZX@1224|Proteobacteria,2U0B6@28211|Alphaproteobacteria,3JWH2@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Phage integrase, N-terminal SAM-like domain - - - - - - - - - - - - Phage_int_SAM_1,Phage_integrase k59_251574_1 1449351.RISW2_12205 7.37e-48 186.0 COG1028@1|root,COG1028@2|Bacteria,1MWC8@1224|Proteobacteria,2TS15@28211|Alphaproteobacteria,4KNC8@93682|Roseivivax 28211|Alphaproteobacteria IQ Short-chain dehydrogenase reductase Sdr - - - - - - - - - - - - - k59_128234_1 1215092.PA6_009_00710 4.76e-11 62.0 2C4JR@1|root,3332P@2|Bacteria,1NCYV@1224|Proteobacteria,1SEKE@1236|Gammaproteobacteria,1YGSY@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_11230_1 570952.ATVH01000019_gene767 5.9e-101 323.0 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,2TVGJ@28211|Alphaproteobacteria,2JPR0@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - k59_11230_2 1380391.JIAS01000005_gene2453 5.29e-25 102.0 28RDB@1|root,2ZDSP@2|Bacteria,1RBF9@1224|Proteobacteria,2U586@28211|Alphaproteobacteria,2JRSR@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - Tube k59_153045_3 1205683.CAKR01000001_gene2100 2.57e-10 66.2 2DBI5@1|root,2Z9EN@2|Bacteria,1PMHG@1224|Proteobacteria,1RQE1@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Exodeoxyribonuclease VIII - - - ko:K10906 - - - - ko00000,ko01000,ko03400 - - - DUF3799 k59_160662_1 1692257.A0A0K1RL39_9CIRC 7.17e-102 307.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_219883_1 1217658.F987_02128 1.4e-19 89.0 COG3772@1|root,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,1SA7C@1236|Gammaproteobacteria,3NSKU@468|Moraxellaceae 1236|Gammaproteobacteria G Phage lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - PG_binding_1,Phage_lysozyme k59_169584_2 1218075.BAYA01000007_gene2719 2.12e-08 59.7 COG4422@1|root,COG4422@2|Bacteria,1MXQI@1224|Proteobacteria,2VJP8@28216|Betaproteobacteria,1K05N@119060|Burkholderiaceae 28216|Betaproteobacteria S PFAM Gp37Gp68 family protein - - - - - - - - - - - - DUF5131 k59_20017_1 1609634.A0A0C5AFV4_9VIRU 2.86e-112 343.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_36986_8 1122182.KB903838_gene4149 5.4e-19 89.0 COG1215@1|root,COG1215@2|Bacteria,2I97V@201174|Actinobacteria,4DF8X@85008|Micromonosporales 201174|Actinobacteria M Glycosyl transferase family group 2 - - - - - - - - - - - - Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2 k59_244137_1 1121091.AUMP01000003_gene2541 6.79e-06 55.1 COG1961@1|root,COG1961@2|Bacteria,1TPUG@1239|Firmicutes,4HB3H@91061|Bacilli 91061|Bacilli L COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - ko:K06400 - - - - ko00000 - - - Recombinase,Resolvase,Zn_ribbon_recom k59_228169_1 1005994.GTGU_01471 0.000396 50.1 COG1783@1|root,COG1783@2|Bacteria,1R66A@1224|Proteobacteria,1RQFD@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage terminase, large subunit Z012_12305 - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C k59_54230_2 1234879.K0A1L0_9CIRC 7.47e-21 97.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_137076_1 948106.AWZT01000001_gene5141 7.44e-101 309.0 2CYA9@1|root,32T3V@2|Bacteria,1RGRN@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_261419_1 67267.JNXT01000054_gene2973 5.49e-24 98.2 2EGA5@1|root,33A1Y@2|Bacteria,2GSDD@201174|Actinobacteria 201174|Actinobacteria S HNH endonuclease - - - - - - - - - - - - HNH_3 k59_161512_3 28152.DJ57_2250 7.01e-21 95.1 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,1RR0M@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_112456_1 428125.CLOLEP_01379 1.76e-47 164.0 COG0553@1|root,COG0553@2|Bacteria,1TS9W@1239|Firmicutes,24CGX@186801|Clostridia,3WN6X@541000|Ruminococcaceae 186801|Clostridia KL Helicase conserved C-terminal domain - - - - - - - - - - - - - k59_54308_2 1150621.SMUL_1068 1.77e-05 48.9 COG3108@1|root,COG3108@2|Bacteria,1NCZX@1224|Proteobacteria,42VTQ@68525|delta/epsilon subdivisions,2YQTW@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria S Peptidase M15 - - - - - - - - - - - - Peptidase_M15_3 k59_261497_2 472175.EL18_02068 3.67e-79 271.0 28HCK@1|root,2Z7PE@2|Bacteria,1NK7S@1224|Proteobacteria,2TSMJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_37051_1 485916.Dtox_0809 6.68e-29 123.0 COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,2605R@186807|Peptococcaceae 186801|Clostridia L DNA polymerase III alpha subunit dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k59_137161_5 357276.EL88_22665 3.94e-29 110.0 COG3108@1|root,COG3108@2|Bacteria,4NW30@976|Bacteroidetes,2FSX2@200643|Bacteroidia,4AR8E@815|Bacteroidaceae 976|Bacteroidetes S Peptidase M15 - - - - - - - - - - - - Peptidase_M15_3 k59_137161_8 1353529.M899_2569 3.86e-15 86.7 COG0729@1|root,COG2911@1|root,COG0729@2|Bacteria,COG2911@2|Bacteria,1N928@1224|Proteobacteria 1224|Proteobacteria M Chaperone of endosialidase - - - - - - - - - - - - Peptidase_S74 k59_244210_1 1101190.ARWB01000001_gene2218 4.42e-43 152.0 COG3409@1|root,COG4322@1|root,COG3409@2|Bacteria,COG4322@2|Bacteria,1R4RS@1224|Proteobacteria,2TYJ9@28211|Alphaproteobacteria 28211|Alphaproteobacteria M CHAP domain - - - - - - - - - - - - CHAP,PG_binding_1 k59_94935_5 1234888.K0A2R8_9VIRU 3.56e-43 155.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_94935_7 1234888.K0A2J2_9VIRU 4.53e-87 276.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_70501_2 243365.CV_2115 3.77e-32 125.0 COG3948@1|root,COG3948@2|Bacteria,1MUFF@1224|Proteobacteria,2VM8A@28216|Betaproteobacteria,2KQIV@206351|Neisseriales 206351|Neisseriales S Baseplate J-like protein - - - - - - - - - - - - Baseplate_J k59_171184_2 667014.Thein_0382 0.000996 46.2 COG2131@1|root,COG2131@2|Bacteria,2GGY9@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria F MafB19-like deaminase - - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 k59_62146_1 1385658.U5KPZ6_9VIRU 3.62e-79 253.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_252983_1 244582.JQAK01000001_gene870 0.00034 47.0 2AJ3M@1|root,319N0@2|Bacteria,1Q39Q@1224|Proteobacteria,2UKWC@28211|Alphaproteobacteria,47FRA@766|Rickettsiales 766|Rickettsiales S Phage gp6-like head-tail connector protein - - - - - - - - - - - - Phage_connect_1 k59_171249_1 1609634.A0A0C5AFV4_9VIRU 1.61e-70 235.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_171249_6 105154.Q9MBU6_9VIRU 1.84e-85 271.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_12851_2 1219076.N646_4295 3.76e-15 75.9 COG4128@1|root,COG4128@2|Bacteria,1RCY8@1224|Proteobacteria,1S4JQ@1236|Gammaproteobacteria,1XX6X@135623|Vibrionales 1236|Gammaproteobacteria S Zonular occludens toxin (Zot) - - - ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko02042 - - - Zot k59_121487_1 358220.C380_09770 5.22e-08 55.5 2EQVQ@1|root,33IFH@2|Bacteria,1PBDY@1224|Proteobacteria,2W6F5@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_137945_1 360910.BAV0432 6.79e-47 171.0 COG3170@1|root,COG3170@2|Bacteria,1Q45C@1224|Proteobacteria,2W196@28216|Betaproteobacteria 28216|Betaproteobacteria NU Tfp pilus assembly protein FimV - - - - - - - - - - - - - k59_46914_3 145579.C_BPPHM 4.27e-12 63.2 4QCC5@10239|Viruses,4QUKW@29258|ssDNA viruses,4QP4C@10841|Microviridae 10841|Microviridae S viral process - - - - - - - - - - - - - k59_79426_1 1237500.ANBA01000003_gene4747 1.68e-20 84.0 2BZTS@1|root,33131@2|Bacteria,2GXUT@201174|Actinobacteria,4EQM9@85012|Streptosporangiales 201174|Actinobacteria - - - - - - - - - - - - - - - k59_221782_1 1498011.A0A096XUW0_9CAUD 8.67e-73 226.0 4QF7M@10239|Viruses,4QSE1@28883|Caudovirales 28883|Caudovirales S AAA domain - - - - - - - - - - - - - k59_95536_1 439375.Oant_2314 2.2e-56 184.0 COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,2TU8N@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_71341_3 1589297.A0A0B5H2N7_9CAUD 2.32e-51 187.0 4QAXA@10239|Viruses,4QQ1A@28883|Caudovirales,4QNU7@10744|Podoviridae 10744|Podoviridae S metallopeptidase activity - - - - - - - - - - - - - k59_62242_1 1609634.A0A0C5AFV4_9VIRU 2.67e-36 137.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_146849_2 1235788.C802_00063 6.62e-40 142.0 COG0847@1|root,COG0847@2|Bacteria,4NPNG@976|Bacteroidetes,2FS7S@200643|Bacteroidia,4ATCY@815|Bacteroidaceae 976|Bacteroidetes L Exonuclease - - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T k59_54991_3 1609634.A0A0C5AFV4_9VIRU 8.03e-152 451.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_113415_1 1122201.AUAZ01000017_gene2947 1.84e-54 191.0 COG0749@1|root,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,465DD@72275|Alteromonadaceae 1236|Gammaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity - - - - - - - - - - - - DNA_pol_A k59_130039_2 518766.Rmar_0924 6.64e-12 61.6 COG2331@1|root,COG2331@2|Bacteria,4P8SQ@976|Bacteroidetes,1FJMJ@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S Putative regulatory protein - - - - - - - - - - - - Zn-ribbon_8 k59_179095_3 1385658.U5KNR1_9VIRU 7.33e-59 197.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_229766_1 145579.CAPSD_BPPHM 2.61e-30 122.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_212301_1 1280944.HY17_04705 5.3e-07 54.7 2E8SI@1|root,3333B@2|Bacteria,1N7MG@1224|Proteobacteria,2UJSF@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_62943_1 192952.MM_0043 4.82e-05 55.8 COG3291@1|root,arCOG02496@1|root,arCOG02496@2157|Archaea,arCOG02507@2157|Archaea,arCOG02546@2157|Archaea,2Y7MW@28890|Euryarchaeota 2157|Archaea S Lactonase, 7-bladed beta-propeller - - 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 - R06200,R11307,R11308 - ko00000,ko00001,ko01000 - GH5,GH9 - Baseplate_J,CARDB,Cellulase,HYR,NosD,PKD,PQQ_3,Polysacc_deac_1,VWA k59_263037_1 754035.Mesau_00724 2.59e-06 50.8 2EBXN@1|root,335X0@2|Bacteria,1RCC3@1224|Proteobacteria,2U2ZA@28211|Alphaproteobacteria,43MK2@69277|Phyllobacteriaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_179948_1 457398.HMPREF0326_03017 4.78e-21 104.0 28HPK@1|root,2Z7XJ@2|Bacteria,1NBHR@1224|Proteobacteria,42YKK@68525|delta/epsilon subdivisions,2WUDS@28221|Deltaproteobacteria,2M8E7@213115|Desulfovibrionales 28221|Deltaproteobacteria S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_253748_1 1477404.A0A023NHR5_9CAUD 8.21e-23 101.0 4QEG2@10239|Viruses,4QVSD@35237|dsDNA viruses no RNA stage,4QRJ9@28883|Caudovirales,4QP0R@10744|Podoviridae 10744|Podoviridae S exonuclease activity - - - - - - - - - - - - - k59_253748_2 655097.C8ZKG2_9CAUD 1.75e-99 320.0 4QGA5@10239|Viruses,4QURD@35237|dsDNA viruses no RNA stage,4QT9N@28883|Caudovirales,4QP47@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_122541_1 1379717.S5SY19_9CIRC 5.57e-44 160.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_55849_5 1219035.NT2_06_02780 2.59e-06 50.4 COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,2TSMA@28211|Alphaproteobacteria,2K1FG@204457|Sphingomonadales 204457|Sphingomonadales H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate ribB - 3.5.4.25,4.1.99.12 ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - - DHBP_synthase,GTP_cyclohydro2,SLT k59_80176_1 1506572.A0A097ZPG0_9CIRC 4.8e-45 159.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_62950_1 658655.HMPREF0988_00879 2.59e-08 56.2 COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,24HF9@186801|Clostridia,27MR3@186928|unclassified Lachnospiraceae 186801|Clostridia L Single-strand binding protein family ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_212307_1 1379715.S5TMW6_9CIRC 8.65e-25 106.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_96288_1 1385658.U5KPZ6_9VIRU 1.02e-72 240.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_253754_1 5722.XP_001284538.1 2.58e-14 81.3 2CRJK@1|root,2R89C@2759|Eukaryota 2759|Eukaryota S DNA polymerase type B, organellar and viral - - - - - - - - - - - - DNA_pol_B_2 k59_139033_1 1618251.A0A0C5I2L8_9CIRC 4.34e-32 128.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_55861_1 1283299.AUKG01000001_gene1815 2.04e-17 86.3 COG0305@1|root,COG0305@2|Bacteria,2GKXQ@201174|Actinobacteria,4CPNU@84995|Rubrobacteria 84995|Rubrobacteria L Participates in initiation and elongation during chromosome replication - - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3 k59_47949_1 28377.ENSACAP00000004404 4.21e-18 84.3 KOG2401@1|root,KOG2401@2759|Eukaryota,3A0U0@33154|Opisthokonta,3BPQY@33208|Metazoa,3CSD1@33213|Bilateria,47Z8J@7711|Chordata,498H2@7742|Vertebrata 33208|Metazoa L AAA domain N4BP2L1 - - - - - - - - - - - AAA_33 k59_195870_1 391613.RTM1035_05070 1.75e-20 97.1 28M7D@1|root,2ZAKV@2|Bacteria,1R6BC@1224|Proteobacteria,2U3UN@28211|Alphaproteobacteria,46P0U@74030|Roseovarius 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_195870_4 1131269.AQVV01000026_gene108 0.00058 40.4 COG0616@1|root,COG0616@2|Bacteria 2|Bacteria OU serine-type peptidase activity sppA - - ko:K04773 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49 k59_212380_1 1096930.L284_17610 2.86e-14 79.3 COG1475@1|root,COG1475@2|Bacteria,1MVF9@1224|Proteobacteria,2TR0P@28211|Alphaproteobacteria,2K1WS@204457|Sphingomonadales 204457|Sphingomonadales K partitioning protein, ParB - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_22543_1 1385658.U5KPZ6_9VIRU 2.04e-63 212.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_254655_1 1437425.CSEC_1182 2.33e-26 116.0 29WX0@1|root,30IJ1@2|Bacteria,2JGR5@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - k59_180878_1 691965.D4P7C3_9CAUD 2.43e-18 79.3 4QDCX@10239|Viruses,4R0GS@35237|dsDNA viruses no RNA stage,4QS3P@28883|Caudovirales,4QKU8@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_180878_2 691965.D4P7C0_9CAUD 9.42e-34 119.0 4QDUR@10239|Viruses,4QVMY@35237|dsDNA viruses no RNA stage,4QU8R@28883|Caudovirales,4QKNQ@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_39267_2 242861.Q6UYH4_9CAUD 5.69e-10 62.8 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_223834_1 649639.Bcell_2721 1.2e-80 274.0 COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,1UHQM@1239|Firmicutes,4HGW7@91061|Bacilli,1ZBWW@1386|Bacillus 91061|Bacilli D phage tail tape measure protein - - - - - - - - - - - - Peptidase_M23,PhageMin_Tail,SLT k59_190065_1 1986029.Q9MBM6_9VIRU 5.04e-21 89.0 4QDBB@10239|Viruses,4QUM0@29258|ssDNA viruses,4QP4D@10841|Microviridae 10841|Microviridae S Chlamydia-phage Chp2 scaffold (Chlamy_scaf) - - - - - - - - - - - - - k59_190065_3 1385658.U5KNR1_9VIRU 2.59e-70 228.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_190065_5 105154.Q9MBU6_9VIRU 8.52e-180 522.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_173439_1 926550.CLDAP_10480 1.53e-07 53.5 COG0399@1|root,COG0399@2|Bacteria 2|Bacteria E UDP-4-amino-4-deoxy-L-arabinose aminotransferase rfbH - 1.17.1.1,4.2.1.164 ko:K12452,ko:K13328 ko00520,ko00523,ko01130,map00520,map00523,map01130 M00802 R03391,R03392,R08930 RC00230,RC00704 ko00000,ko00001,ko00002,ko01000 - - - DegT_DnrJ_EryC1 k59_148945_1 691965.D4P7L3_9CAUD 1.36e-27 112.0 4QBH7@10239|Viruses,4QWWF@35237|dsDNA viruses no RNA stage,4QQ8R@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_39389_1 1123279.ATUS01000001_gene2720 3.25e-73 232.0 COG4128@1|root,COG4128@2|Bacteria,1RCY8@1224|Proteobacteria,1S4JQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Zonular occludens toxin (Zot) - - - ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko02042 - - - Zot k59_206256_2 105154.Q9MBU3_9VIRU 2.32e-08 60.1 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_22670_1 2003327.CAPSD_BPCHP 2.76e-21 97.1 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_39391_3 1165094.RINTHH_3920 6.13e-29 114.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_63797_1 526118.D1FNQ5_9CAUD 2.14e-48 176.0 4QBMV@10239|Viruses,4QUU6@35237|dsDNA viruses no RNA stage,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_157285_1 1618248.A0A0C5IB82_9CIRC 6.13e-103 311.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_181771_1 1618248.A0A0C5IB82_9CIRC 1.53e-24 100.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_264894_2 1574422.A0A0A1ENW9_9CIRC 4.36e-48 169.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_231621_2 1536597.A0A088F6J4_9CAUD 4.71e-22 95.5 4QAIK@10239|Viruses,4QPEB@28883|Caudovirales,4QP3P@10744|Podoviridae 10744|Podoviridae S phosphoprotein phosphatase activity - - - - - - - - - - - - - k59_23634_3 1609634.A0A0C5ANA6_9VIRU 6.21e-15 79.0 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_74160_2 1420600.W5RNT1_9CIRC 2.8e-41 155.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_238816_2 3218.PP1S155_86V6.2 8.35e-20 102.0 28HK1@1|root,2QPXS@2759|Eukaryota,37NXW@33090|Viridiplantae,3GF00@35493|Streptophyta 35493|Streptophyta L Twinkle homolog protein chloroplastic - GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003697,GO:0003824,GO:0003896,GO:0003899,GO:0004003,GO:0004386,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016043,GO:0016070,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032392,GO:0032508,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051276,GO:0055086,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090407,GO:0097159,GO:0097747,GO:0140097,GO:0140098,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - DnaB_C,Toprim_4 k59_57698_1 1408418.JNJH01000043_gene3133 4.36e-33 123.0 2EPAR@1|root,33GXH@2|Bacteria,1N7YQ@1224|Proteobacteria,2UGER@28211|Alphaproteobacteria 28211|Alphaproteobacteria S RyR domain - - - - - - - - - - - - RyR k59_214073_1 105154.Q9MBU6_9VIRU 9.86e-60 202.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_15292_1 1453501.JELR01000001_gene2516 2.74e-34 139.0 COG4733@1|root,COG4926@1|root,COG4733@2|Bacteria,COG4926@2|Bacteria,1R77Q@1224|Proteobacteria,1S1WT@1236|Gammaproteobacteria,469QU@72275|Alteromonadaceae 1236|Gammaproteobacteria S Fibronectin type 3 domain - - - - - - - - - - - - - k59_132649_1 1618254.A0A0C5IBG4_9CIRC 1.91e-110 326.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_74179_1 753084.F4YCL1_9CAUD 1.17e-05 54.7 4QHBW@10239|Viruses,4R0DB@35237|dsDNA viruses no RNA stage,4QSXW@28883|Caudovirales,4QMB4@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_264895_5 1220583.GOACH_33_00170 3.3e-05 46.2 2AQ11@1|root,31F61@2|Bacteria,2HIJ0@201174|Actinobacteria,4GF7Q@85026|Gordoniaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_197987_2 1173264.KI913949_gene396 7.24e-58 195.0 COG1351@1|root,COG1351@2|Bacteria,1G1PU@1117|Cyanobacteria,1H8RR@1150|Oscillatoriales 1117|Cyanobacteria F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant thyX - 2.1.1.148 ko:K03465 ko00240,ko00670,ko01100,map00240,map00670,map01100 - R06613 RC00022,RC00332 ko00000,ko00001,ko01000 - - - HNH,Intein_splicing,Thy1 k59_64780_1 502025.Hoch_4030 1.57e-13 75.5 COG3119@1|root,COG3119@2|Bacteria,1QZHU@1224|Proteobacteria,42PUM@68525|delta/epsilon subdivisions,2X7T5@28221|Deltaproteobacteria,2Z00V@29|Myxococcales 28221|Deltaproteobacteria P Sulfatase - - 3.1.6.6 ko:K01133 - - - - ko00000,ko01000 - - - Cu-binding_MopE,Sulfatase k59_107368_2 1121033.AUCF01000017_gene3816 1.3e-20 90.1 COG0741@1|root,COG0741@2|Bacteria,1N0U8@1224|Proteobacteria,2UICK@28211|Alphaproteobacteria,2JTZJ@204441|Rhodospirillales 204441|Rhodospirillales M lytic transglycosylase activity - - - - - - - - - - - - - k59_265024_1 1692256.A0A0K1RL85_9CIRC 1.52e-90 277.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_89515_1 691965.D4P7D6_9CAUD 5.33e-15 74.3 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_89515_2 742740.HMPREF9474_02268 4.95e-39 133.0 2E2Y0@1|root,32XYV@2|Bacteria,1VD9S@1239|Firmicutes,24PK0@186801|Clostridia,2236I@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_89515_4 742740.HMPREF9474_02267 1.81e-41 143.0 28NM4@1|root,2ZBMQ@2|Bacteria,1V1QD@1239|Firmicutes,24G1B@186801|Clostridia,221N8@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_24848_1 1122201.AUAZ01000017_gene2962 4.92e-17 88.2 COG4675@1|root,COG4675@2|Bacteria 2|Bacteria M tail collar domain protein - - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - Collar,Phage_fiber_2 k59_16371_1 1380894.S5TR92_9CIRC 3.27e-34 131.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_265025_2 1692244.A0A0K1RLR5_9CIRC 7.49e-43 154.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_24852_2 1379707.S5T672_9CIRC 5.04e-41 148.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_215229_2 661478.OP10G_3777 8.04e-11 68.9 COG1472@1|root,COG1472@2|Bacteria 2|Bacteria G Belongs to the glycosyl hydrolase 3 family - - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,PA14 k59_240061_1 1692250.A0A0K1RLR1_9CIRC 4.59e-56 185.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_265052_3 1379708.S5SYC3_9CIRC 4.78e-32 123.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_41388_1 1117314.PCIT_10369 1.29e-09 64.7 2DI1X@1|root,32UA7@2|Bacteria,1N6BQ@1224|Proteobacteria,1SBG2@1236|Gammaproteobacteria,2Q4VW@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_240064_1 765698.Mesci_3835 1.24e-55 189.0 COG5323@1|root,COG5323@2|Bacteria,1R049@1224|Proteobacteria 1224|Proteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6 k59_65784_1 1297863.APJF01000020_gene2704 9.49e-05 53.9 28JTG@1|root,2Z9IR@2|Bacteria,1R0GC@1224|Proteobacteria,2TURR@28211|Alphaproteobacteria,3JUCC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF2793) - - - - - - - - - - - - DUF2793 k59_65784_3 1205680.CAKO01000006_gene3232 5.7e-14 75.5 2DTAA@1|root,33JEH@2|Bacteria,1NFFI@1224|Proteobacteria,2UFJK@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_215232_1 1385658.U5KNR1_9VIRU 2.75e-82 257.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_107474_1 1165094.RINTHH_3920 8.76e-39 141.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_166147_1 1618256.A0A0C5IM93_9CIRC 3.46e-29 115.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_41860_2 1618248.A0A0C5IB82_9CIRC 8.11e-07 53.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_191062_1 1676184.A0A186YBN5_9CIRC 8.2e-33 130.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_66671_1 444876.E3SQL7_9CAUD 8.77e-33 125.0 4QAM2@10239|Viruses,4QV3W@35237|dsDNA viruses no RNA stage,4QPGK@28883|Caudovirales 28883|Caudovirales S catalytic activity - GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004521,GO:0004523,GO:0004527,GO:0004536,GO:0004540,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008409,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016888,GO:0016891,GO:0016893,GO:0017108,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048256,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140097,GO:0140098,GO:1901360 - - - - - - - - - - - k59_99861_3 1234888.K0A2J2_9VIRU 9.9e-117 359.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_182903_1 1141137.K4FBB3_9CAUD 5.24e-12 70.9 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_66790_2 103807.Q9MBZ3_9CAUD 1.1e-24 97.8 4QHC8@10239|Viruses,4QZ9A@35237|dsDNA viruses no RNA stage,4QSRC@28883|Caudovirales,4QKFD@10662|Myoviridae 10662|Myoviridae S D-alanyl-D-alanine carboxypeptidase - - - - - - - - - - - - - k59_182904_1 1094563.MCQ_01488 4.81e-28 117.0 COG3170@1|root,COG3170@2|Bacteria,1R69E@1224|Proteobacteria,2U3B9@28211|Alphaproteobacteria,48T9Q@772|Bartonellaceae 28211|Alphaproteobacteria NU Phage P22-like portal protein - - - - - - - - - - - - P22_portal k59_240935_1 911008.GLAD_04128 2.99e-24 110.0 COG4695@1|root,COG4695@2|Bacteria,1MUP5@1224|Proteobacteria,1RPB0@1236|Gammaproteobacteria 1236|Gammaproteobacteria S portal protein - - - - - - - - - - - - Phage_portal k59_257586_4 1094508.Tsac_2684 4.16e-46 176.0 COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,247R7@186801|Clostridia,42FCZ@68295|Thermoanaerobacterales 186801|Clostridia L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity recD2 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 k59_42002_1 691965.D4P7I3_9CAUD 1.33e-122 394.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_141436_2 472175.EL18_01406 1.82e-32 131.0 COG3723@1|root,COG3723@2|Bacteria,1R6DB@1224|Proteobacteria,2U82T@28211|Alphaproteobacteria 28211|Alphaproteobacteria L RecT family - - - ko:K07455 - - - - ko00000,ko03400 - - - RecT k59_116568_1 316274.Haur_1369 1.89e-38 147.0 COG4372@1|root,COG5283@1|root,COG5412@1|root,COG4372@2|Bacteria,COG5283@2|Bacteria,COG5412@2|Bacteria,2G9J0@200795|Chloroflexi 2|Bacteria M TIGRFAM phage tail tape measure protein, TP901 family Z012_10445 - - ko:K01991,ko:K07161,ko:K07484 ko02026,map02026 - - - ko00000,ko00001,ko02000 1.B.18 - - DDE_Tnp_IS66,DUF3084,LZ_Tnp_IS66,PhageMin_Tail,zf-IS66 k59_191150_2 316067.Geob_3483 4.33e-16 78.2 COG0279@1|root,COG0279@2|Bacteria,1NJ8X@1224|Proteobacteria,43ADJ@68525|delta/epsilon subdivisions,2WMPS@28221|Deltaproteobacteria,43TG6@69541|Desulfuromonadales 28221|Deltaproteobacteria F Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate gmhA - 5.3.1.28 ko:K03271 ko00540,ko01100,map00540,map01100 M00064 R05645,R09768,R09769 RC00434 ko00000,ko00001,ko00002,ko01000,ko01005 - - iAF987.Gmet_0920 SIS_2 k59_141439_1 913970.F8RW84_9VIRU 1.51e-21 99.0 4QCVK@10239|Viruses,4QUMV@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_8806_1 105154.Q9MBU6_9VIRU 4.37e-145 430.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_134032_1 172088.AUGA01000017_gene2380 2.81e-59 194.0 COG3206@1|root,COG3206@2|Bacteria,1ND5H@1224|Proteobacteria,2UIQZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria M protein involved in exopolysaccharide biosynthesis - - - - - - - - - - - - - k59_42776_1 546275.FUSPEROL_02001 1.04e-21 89.0 COG3108@1|root,COG3108@2|Bacteria,37ATH@32066|Fusobacteria 32066|Fusobacteria S D-alanyl-D-alanine carboxypeptidase - - - - - - - - - - - - Peptidase_M15_4 k59_175099_1 243274.THEMA_06150 1.28e-13 78.6 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2GCCM@200918|Thermotogae 200918|Thermotogae L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_175099_2 1278073.MYSTI_01964 3.46e-27 110.0 COG1896@1|root,COG1896@2|Bacteria,1RACF@1224|Proteobacteria,431GD@68525|delta/epsilon subdivisions,2WWJC@28221|Deltaproteobacteria 28221|Deltaproteobacteria S hydrolases of HD superfamily - - - ko:K06952 - - - - ko00000 - - - - k59_167154_1 105154.Q9MBU6_9VIRU 1.19e-67 222.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_1496_1 573413.Spirs_2515 3.37e-212 618.0 COG0553@1|root,COG0863@1|root,COG0553@2|Bacteria,COG0863@2|Bacteria,2JA5J@203691|Spirochaetes 203691|Spirochaetes H SNF2 family N-terminal domain - - - - - - - - - - - - N6_N4_Mtase k59_26357_1 1477404.A0A023NHT3_9CAUD 1.12e-11 70.5 4QE4R@10239|Viruses,4QWC7@35237|dsDNA viruses no RNA stage,4QQNJ@28883|Caudovirales,4QP0Z@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_258571_1 1692257.A0A0K1RL39_9CIRC 5.55e-31 120.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_200199_4 317025.Tcr_1554 2.19e-15 83.2 COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,1RMQN@1236|Gammaproteobacteria,460B0@72273|Thiotrichales 72273|Thiotrichales T PFAM PhoH-like protein - - - ko:K07175 - - - - ko00000 - - - PIN_4,PhoH k59_1510_1 1234888.K0A2J2_9VIRU 3.51e-48 172.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_9407_3 753084.F4YCI6_9CAUD 1.09e-09 58.2 4QAIJ@10239|Viruses,4QVZ9@35237|dsDNA viruses no RNA stage,4QPXI@28883|Caudovirales,4QM02@10699|Siphoviridae 10699|Siphoviridae S C-5 cytosine-specific DNA methylase - - - - - - - - - - - - - k59_217137_1 272942.RCAP_rcc00961 5.8e-24 109.0 COG4672@1|root,COG4672@2|Bacteria 2|Bacteria S Phage minor tail protein L - - - - - - - - - - - - - k59_51210_1 626939.HMPREF9443_01159 1.09e-05 53.1 COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,4H2P0@909932|Negativicutes 909932|Negativicutes K Belongs to the ParB family spo0J - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_68386_1 477974.Daud_0937 2.37e-14 71.6 COG0756@1|root,COG0756@2|Bacteria,1V6HX@1239|Firmicutes,24K3X@186801|Clostridia,2624W@186807|Peptococcaceae 186801|Clostridia F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA dut - 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase k59_226188_1 156889.Mmc1_2604 1.87e-69 229.0 COG1475@1|root,COG4725@1|root,COG1475@2|Bacteria,COG4725@2|Bacteria,1R553@1224|Proteobacteria,2TRP6@28211|Alphaproteobacteria 28211|Alphaproteobacteria KT Belongs to the MT-A70-like family - - - - - - - - - - - - MT-A70 k59_59954_1 2754.EH55_08530 9.49e-49 171.0 COG0507@1|root,COG0507@2|Bacteria 2|Bacteria L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD - - - - - - - - - - - - AAA_30,HTH_31,N_BRCA1_IG k59_242483_1 714943.Mucpa_3799 4.43e-26 109.0 28N1N@1|root,2ZB7Q@2|Bacteria,4NPUX@976|Bacteroidetes 976|Bacteroidetes H PFAM Sulfotransferase domain - - - - - - - - - - - - Sulfotransfer_1 k59_218281_1 1265490.JHVY01000003_gene3201 2.1e-55 189.0 COG4294@1|root,COG4294@2|Bacteria,1QNKU@1224|Proteobacteria,1S2Y2@1236|Gammaproteobacteria 1236|Gammaproteobacteria L UV damage repair endonuclease uvsE - - ko:K13281 - - - - ko00000,ko01000 - - - UvdE k59_176048_1 1609634.A0A0C5AFV4_9VIRU 1.22e-60 204.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_143485_2 1540095.A0A0A0YP73_9CAUD 1.37e-11 65.9 4QAVB@10239|Viruses,4QPIJ@28883|Caudovirales,4QI48@10662|Myoviridae 10662|Myoviridae S defense response to bacterium - - - - - - - - - - - - - k59_10166_1 105154.Q9MBU3_9VIRU 8.74e-06 51.6 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_218287_1 655097.C8ZKI4_9CAUD 1.77e-134 397.0 4QEFX@10239|Viruses,4QYYG@35237|dsDNA viruses no RNA stage,4QRRV@28883|Caudovirales,4QNTK@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_101784_2 1692253.A0A0K1RLM4_9CIRC 7.13e-20 92.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_110098_1 1379719.S5TMX6_9CIRC 8.32e-38 143.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_126969_1 1385658.U5KPZ6_9VIRU 1.77e-100 311.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_27438_1 294631.Q5ZGF6_9CAUD 1.06e-117 350.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0019012,GO:0019028,GO:0042802,GO:0044423 - - - - - - - - - - - k59_43729_1 1458275.AZ34_10360 1.68e-32 121.0 2EKAP@1|root,33E0Y@2|Bacteria,1NAAI@1224|Proteobacteria,2VZTN@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_250682_1 1788447.A0A190WHJ9_9CIRC 4.56e-89 271.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_193152_1 1121440.AUMA01000005_gene2577 1.64e-19 92.4 COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1R7DJ@1224|Proteobacteria,4321W@68525|delta/epsilon subdivisions,2WWR1@28221|Deltaproteobacteria,2M9G9@213115|Desulfovibrionales 28221|Deltaproteobacteria H Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - - - - - - - - - - CTP_transf_like,PfkB k59_77735_1 1382303.JPOM01000001_gene1002 4.66e-13 73.6 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TR1I@28211|Alphaproteobacteria,2KEXP@204458|Caulobacterales 204458|Caulobacterales H acetolactate synthase large subunit - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k59_77735_2 1537917.JU82_09645 9.06e-26 106.0 COG0535@1|root,COG0535@2|Bacteria,1PHAQ@1224|Proteobacteria,42QIE@68525|delta/epsilon subdivisions,2YNUJ@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria C Iron-sulfur cluster-binding domain - - - - - - - - - - - - Radical_SAM,SPASM k59_135846_2 1609634.A0A0C5AFV4_9VIRU 2.33e-101 312.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_127800_2 1379725.S5TMY9_9CIRC 4.96e-27 116.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_219381_1 1437329.A0A0A8KWW6_9CAUD 5.5e-22 99.8 4QAWG@10239|Viruses,4QZ9F@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales,4QNBW@10744|Podoviridae 10744|Podoviridae S DNA helicase activity - - - - - - - - - - - - - k59_243251_4 223926.28806566 2.52e-13 75.1 2CEFX@1|root,34B3J@2|Bacteria,1P0R4@1224|Proteobacteria,1SSPS@1236|Gammaproteobacteria,1XTMJ@135623|Vibrionales 135623|Vibrionales - - VPA0901 - - - - - - - - - - - - k59_119393_2 1219035.NT2_13_00580 2.39e-62 214.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_219383_1 375286.mma_2205 3.59e-21 98.6 COG2268@1|root,COG2268@2|Bacteria,1NT13@1224|Proteobacteria 1224|Proteobacteria S Band 7 protein - - - - - - - - - - - - - k59_251377_1 1211777.BN77_4169 2.57e-44 154.0 2C5GI@1|root,2Z8C1@2|Bacteria,1R8XM@1224|Proteobacteria,2TUME@28211|Alphaproteobacteria,4BJKS@82115|Rhizobiaceae 28211|Alphaproteobacteria S P22 coat protein - gene protein 5 - - - - - - - - - - - - P22_CoatProtein k59_77899_2 1219076.N646_0606 1.38e-10 60.8 2CHQ6@1|root,33N6R@2|Bacteria,1NM75@1224|Proteobacteria,1SUNZ@1236|Gammaproteobacteria,1Y1UP@135623|Vibrionales 1236|Gammaproteobacteria S Protein of unknown function (DUF2523) - - - - - - - - - - - - DUF2523 k59_77899_3 1245471.PCA10_28690 6.57e-05 47.8 2FJ35@1|root,34ATG@2|Bacteria,1P008@1224|Proteobacteria,1SW0Q@1236|Gammaproteobacteria,1YK4X@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_85337_1 488538.SAR116_2145 1.79e-31 114.0 COG3023@1|root,COG3023@2|Bacteria,1N032@1224|Proteobacteria 1224|Proteobacteria V N-acetylmuramoyl-L-alanine amidase - - 3.5.1.28 ko:K01447 - - R04112 RC00064,RC00141 ko00000,ko01000 - - - Amidase_2,PG_binding_1 k59_185463_1 428125.CLOLEP_03914 6.06e-06 54.3 COG1215@1|root,COG1216@1|root,COG2227@1|root,COG1215@2|Bacteria,COG1216@2|Bacteria,COG2227@2|Bacteria,1TQU0@1239|Firmicutes,248HP@186801|Clostridia,3WHZS@541000|Ruminococcaceae 186801|Clostridia M Glycosyltransferase, group 2 family protein - - - ko:K20444 - - - - ko00000,ko01000,ko01005,ko02000 4.D.1.3 GT2,GT4 - Glycos_transf_2 k59_177182_1 1341155.FSS13T_20370 0.000256 52.0 COG3291@1|root,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia,2NU73@237|Flavobacterium 976|Bacteroidetes O C-terminal domain of CHU protein family - - - - - - - - - - - - CHU_C,HYR,SprB k59_28476_2 1230476.C207_06817 2.52e-16 79.3 COG5108@1|root,COG5108@2|Bacteria,1NMT3@1224|Proteobacteria,2UMAD@28211|Alphaproteobacteria,3K3WT@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K dna-directed rna polymerase - - - - - - - - - - - - - k59_36099_1 105154.Q9MBU6_9VIRU 2.39e-184 532.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_36099_2 105154.Q9MBU3_9VIRU 5.66e-09 61.6 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_36099_5 1165094.RINTHH_3920 4.24e-75 239.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_94042_1 1692248.A0A0K1RLN2_9CIRC 2.27e-50 173.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_136008_2 685778.AORL01000021_gene1193 1.49e-53 177.0 COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,2TU8N@28211|Alphaproteobacteria,2K409@204457|Sphingomonadales 204457|Sphingomonadales L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_235757_1 1385658.U5KPZ6_9VIRU 1.19e-138 413.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_86402_5 105154.Q9MBU6_9VIRU 5.75e-202 580.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_86402_7 1385658.U5KNR1_9VIRU 1.2e-74 238.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_252570_1 926550.CLDAP_25590 1.2e-19 90.5 COG1572@1|root,COG1572@2|Bacteria 2|Bacteria NU bacterial-type flagellum-dependent cell motility - - - - - - - - - - - - BatA,CARDB,DUF3367,DUF4091,DUF4159 k59_78977_1 1463921.JODF01000103_gene5755 3.67e-23 95.9 COG0629@1|root,COG0629@2|Bacteria,2IH2G@201174|Actinobacteria 201174|Actinobacteria L Single-strand binding protein family - - - - - - - - - - - - SSB k59_203615_1 1379708.S5TNB8_9CIRC 5.64e-34 132.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_54470_4 1618249.A0A0C5IBT4_9CIRC 3.18e-19 93.2 4QB6C@10239|Viruses,4QUKM@29258|ssDNA viruses 10239|Viruses J Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_228491_1 388051.AUFE01000035_gene4020 1.58e-133 395.0 COG4653@1|root,COG4653@2|Bacteria 2|Bacteria G Phage capsid family - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_203833_2 105154.Q9MBU3_9VIRU 3.29e-05 50.1 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_178757_2 1385658.U5KNR1_9VIRU 1.07e-27 111.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_129681_2 1548905.A0A0A1IUL8_9CAUD 1.6e-128 379.0 4QBA2@10239|Viruses,4QPPI@28883|Caudovirales,4QM0B@10699|Siphoviridae 10699|Siphoviridae S Thymidylate synthase - GO:0003674,GO:0003824,GO:0004799,GO:0008150,GO:0008152,GO:0008168,GO:0016740,GO:0016741,GO:0032259,GO:0042083 - - - - - - - - - - - k59_129681_4 462590.A9J514_BPPYU 3.99e-07 55.8 4QERE@10239|Viruses,4QUSA@35237|dsDNA viruses no RNA stage,4QT0F@28883|Caudovirales,4QKN8@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_129681_5 1548905.A0A0A1IWZ2_9CAUD 1.31e-100 303.0 4QG7K@10239|Viruses,4QQZP@28883|Caudovirales,4QN68@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_129681_8 1548905.A0A0A1IUL6_9CAUD 2.01e-80 252.0 4QH1V@10239|Viruses,4QPQV@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_129681_12 394221.Mmar10_0401 1.47e-163 467.0 COG0208@1|root,COG0208@2|Bacteria,1MWUS@1224|Proteobacteria,2TS3X@28211|Alphaproteobacteria,43WU8@69657|Hyphomonadaceae 28211|Alphaproteobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdF - 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_sm k59_129681_13 1044.EH31_15000 3.98e-270 761.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2TS19@28211|Alphaproteobacteria,2K0F8@204457|Sphingomonadales 204457|Sphingomonadales F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdA - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_lgC,Ribonuc_red_lgN k59_129681_14 1548905.A0A0A1IWK7_9CAUD 2.47e-164 473.0 4QBY0@10239|Viruses,4QQ4Q@28883|Caudovirales,4QNAU@10699|Siphoviridae 10699|Siphoviridae S UvrD-like helicase C-terminal domain - - - - - - - - - - - - - k59_129681_15 1548905.A0A0A1IUL4_9CAUD 3.06e-125 364.0 4QCW5@10239|Viruses,4QQVP@28883|Caudovirales,4QKSV@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_129681_16 1548905.A0A0A1IWY7_9CAUD 7.53e-45 153.0 4QEKD@10239|Viruses,4QQVS@28883|Caudovirales,4QN8Y@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_262859_1 2003327.CAPSD_BPCHP 1.98e-34 135.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_205088_2 1218075.BAYA01000001_gene421 1.4e-46 167.0 28PTM@1|root,2ZCEU@2|Bacteria,1R5DD@1224|Proteobacteria,2W259@28216|Betaproteobacteria 28216|Betaproteobacteria S Family of unknown function (DUF5309) - - - - - - - - - - - - DUF5309 k59_31284_1 1476391.X5L0Y9_9CAUD 8.78e-29 121.0 4QB3X@10239|Viruses,4QWKP@35237|dsDNA viruses no RNA stage,4QPEE@28883|Caudovirales,4QNCI@10744|Podoviridae 10744|Podoviridae S VWA-like domain (DUF2201) - - - - - - - - - - - - - k59_195812_1 1394178.AWOO02000044_gene4503 8.41e-21 94.0 COG0639@1|root,COG0639@2|Bacteria,2I6ZG@201174|Actinobacteria 201174|Actinobacteria T Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP - - - - - - - - - - - - Metallophos k59_229722_1 585503.HMPREF7545_1731 3.4e-42 155.0 COG5323@1|root,COG5323@2|Bacteria,1UMAZ@1239|Firmicutes,4H9ED@909932|Negativicutes 909932|Negativicutes S Terminase-like family - - - - - - - - - - - - Terminase_6 k59_212274_5 77856.REP_BFDV 1.13e-33 129.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_172203_1 490913.B0FLN5_9CAUD 2.88e-33 131.0 4QGGR@10239|Viruses,4QZHR@35237|dsDNA viruses no RNA stage,4QUGZ@28883|Caudovirales,4QNY3@10744|Podoviridae 10744|Podoviridae S viral capsid - - - - - - - - - - - - - k59_47890_1 691965.D4P7I3_9CAUD 5.64e-30 121.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_236984_1 857087.Metme_2336 4.69e-44 156.0 2CI0W@1|root,2Z81W@2|Bacteria,1R9FZ@1224|Proteobacteria,1S0NA@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage X family - - - - - - - - - - - - Phage_CRI,Phage_X k59_38343_3 1609634.A0A0C5AFV4_9VIRU 1.88e-218 621.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_38343_4 1609634.A0A0C5ANA6_9VIRU 6.4e-22 91.7 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_222788_1 1609634.A0A0C5AFV4_9VIRU 1.39e-68 225.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_222788_5 1609634.A0A0C5AFT2_9VIRU 3.35e-24 100.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_81017_2 1234888.K0A2R8_9VIRU 8.47e-13 73.6 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_32391_2 1283340.Q6WI94_BPKVM 6.17e-52 189.0 4QAUT@10239|Viruses,4QVIM@35237|dsDNA viruses no RNA stage,4QQ7X@28883|Caudovirales,4QIGV@10662|Myoviridae 10662|Myoviridae S DNA ligase (ATP) activity - - - - - - - - - - - - - k59_206160_1 1986029.Q9MBM6_9VIRU 5.43e-13 69.3 4QDBB@10239|Viruses,4QUM0@29258|ssDNA viruses,4QP4D@10841|Microviridae 10841|Microviridae S Chlamydia-phage Chp2 scaffold (Chlamy_scaf) - - - - - - - - - - - - - k59_32392_1 438753.AZC_3575 7.44e-55 190.0 COG5410@1|root,COG5410@2|Bacteria,1N0W2@1224|Proteobacteria,2U18J@28211|Alphaproteobacteria 28211|Alphaproteobacteria K chromosome segregation - - - - - - - - - - - - Terminase_6C k59_148840_1 1321779.HMPREF1984_01321 1.22e-35 147.0 COG0749@1|root,COG0749@2|Bacteria,37BV5@32066|Fusobacteria 32066|Fusobacteria L DNA polymerase A domain - - - - - - - - - - - - DNA_pol_A k59_73296_4 1207076.ALAT01000042_gene3404 8.41e-14 66.6 2EURW@1|root,33N7G@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - HTH_17 k59_32395_1 691965.D4P7I3_9CAUD 4.78e-43 160.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_180890_2 1051675.G0YQI0_9CAUD 3.51e-18 87.0 4QF3C@10239|Viruses,4QWIA@35237|dsDNA viruses no RNA stage,4QU4U@28883|Caudovirales,4QNNQ@10744|Podoviridae 10744|Podoviridae S host cell wall - - - - - - - - - - - - - k59_237833_1 319003.Bra1253DRAFT_08459 1.9e-06 58.2 2F5DG@1|root,33XZC@2|Bacteria,1RKCR@1224|Proteobacteria,2UBMH@28211|Alphaproteobacteria,3K2MH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_81019_1 243231.GSU0279 0.000129 52.4 COG2373@1|root,COG2931@1|root,COG3210@1|root,COG5295@1|root,COG2373@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG5295@2|Bacteria,1MU7T@1224|Proteobacteria 1224|Proteobacteria Q COG2931, RTX toxins and related Ca2 -binding proteins - - - - - - - - - - - - Calx-beta,TIG k59_173370_1 1122225.AULQ01000004_gene2180 1.36e-13 66.2 COG1525@1|root,COG1525@2|Bacteria,4NR4U@976|Bacteroidetes,1I3CI@117743|Flavobacteriia 976|Bacteroidetes L Staphylococcal nuclease homologue - - 3.1.31.1 ko:K01174 - - - - ko00000,ko01000 - - - SNase k59_181821_1 1379725.S5TMY9_9CIRC 2.16e-23 101.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_157370_1 1609634.A0A0C5AFV4_9VIRU 6.59e-102 312.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_15357_2 1788442.A0A190WH98_9CIRC 7.45e-17 85.1 4QB6C@10239|Viruses,4QUKM@29258|ssDNA viruses 10239|Viruses J Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_165083_1 742767.HMPREF9456_03236 1.57e-43 156.0 COG1783@1|root,COG1783@2|Bacteria,4NHPB@976|Bacteroidetes,2FR95@200643|Bacteroidia,22WQM@171551|Porphyromonadaceae 976|Bacteroidetes S Terminase RNAseH like domain - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C k59_57780_1 428125.CLOLEP_01400 1.3e-38 149.0 28JED@1|root,2Z98K@2|Bacteria,1TW1U@1239|Firmicutes,24CFD@186801|Clostridia,3WNW0@541000|Ruminococcaceae 186801|Clostridia K Bacterial regulatory proteins, luxR family - - - - - - - - - - - - GerE k59_57780_2 742733.HMPREF9469_05040 5.82e-24 96.3 29YRZ@1|root,30KMY@2|Bacteria,1V4Y4@1239|Firmicutes,24HPY@186801|Clostridia,221XY@1506553|Lachnoclostridium 186801|Clostridia S Protein of unknown function (DUF2800) - - - - - - - - - - - - DUF2800 k59_106783_3 1618248.A0A0C5IB82_9CIRC 1.62e-05 53.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_264899_1 1385658.U5KPZ6_9VIRU 1.4e-158 464.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_264899_3 105154.Q9MBU2_9VIRU 1.16e-19 87.4 4QDBB@10239|Viruses,4QUM0@29258|ssDNA viruses,4QP4D@10841|Microviridae 10841|Microviridae S Chlamydia-phage Chp2 scaffold (Chlamy_scaf) - - - - - - - - - - - - - k59_264899_4 1986029.Q9MBM3_9VIRU 8.12e-73 235.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_264899_6 1609634.A0A0C5AFV4_9VIRU 2.18e-48 170.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_165085_2 1522072.IL54_4401 7.17e-08 59.7 2DGEH@1|root,2ZVMZ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_181845_1 1536592.A0A088FB29_9VIRU 6.12e-30 119.0 4QB5I@10239|Viruses 10239|Viruses S N-methyltransferase activity - - - - - - - - - - - - - k59_82134_1 1217658.F987_01480 3.35e-39 146.0 COG5410@1|root,COG5410@2|Bacteria,1N0W2@1224|Proteobacteria,1S03G@1236|Gammaproteobacteria,3NJ72@468|Moraxellaceae 1236|Gammaproteobacteria K chromosome segregation - - - - - - - - - - - - - k59_82290_1 205914.HS_1402 1.27e-16 85.1 COG0640@1|root,COG0640@2|Bacteria,1QX1B@1224|Proteobacteria,1T334@1236|Gammaproteobacteria,1Y983@135625|Pasteurellales 135625|Pasteurellales K Transcriptional regulator - - - - - - - - - - - - - k59_40478_2 1250232.JQNJ01000001_gene3360 1.64e-71 238.0 COG3291@1|root,COG3291@2|Bacteria,4PMR5@976|Bacteroidetes,1IJX3@117743|Flavobacteriia 976|Bacteroidetes N cellulose binding - - - - - - - - - - - - Big_2 k59_57935_2 1788447.A0A190WHJ9_9CIRC 4.49e-104 310.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_98118_1 105154.Q9MBU3_9VIRU 9.14e-13 71.6 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_23959_1 1458848.X2KMJ3_9CAUD 8.17e-57 191.0 4QBYE@10239|Viruses,4QVYH@35237|dsDNA viruses no RNA stage,4QQTP@28883|Caudovirales,4QP46@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_23959_2 10752.Q859Q4_BPN4 5.41e-38 137.0 4QDXM@10239|Viruses,4QWIX@35237|dsDNA viruses no RNA stage,4QQF6@28883|Caudovirales,4QNXH@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_99099_3 1121935.AQXX01000137_gene3938 2.41e-18 89.7 COG0503@1|root,COG0503@2|Bacteria 2|Bacteria F purine ribonucleoside salvage apt - 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 - R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 - - - Pribosyltran k59_107604_2 1692244.A0A0K1RLR5_9CIRC 2.43e-80 250.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_215424_2 2003327.CAPSD_BPCHP 3.43e-115 360.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_265150_4 105154.Q9MBU3_9VIRU 6.84e-20 90.5 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_265150_5 1385658.U5KPZ6_9VIRU 7.2e-194 559.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_248706_1 1165094.RINTHH_3920 2.8e-62 204.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_248706_4 105154.Q9MBU3_9VIRU 5.35e-17 82.4 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_248706_5 1385658.U5KPZ6_9VIRU 1.08e-218 622.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_90357_1 1270196.JCKI01000013_gene3205 0.0 889.0 28IN7@1|root,2Z8NM@2|Bacteria,4NHTH@976|Bacteroidetes 976|Bacteroidetes S Capsid protein (F protein) - - - - - - - - - - - - Phage_F k59_90357_2 1286632.P278_33640 2.15e-124 354.0 28HGS@1|root,2Z7SJ@2|Bacteria,4NERU@976|Bacteroidetes,1HZIZ@117743|Flavobacteriia 976|Bacteroidetes S Major spike protein (G protein) - - - - - - - - - - - - Phage_G k59_90357_3 1288298.rosmuc_01659 6.62e-188 527.0 2DBBW@1|root,2Z8AR@2|Bacteria,1R492@1224|Proteobacteria,2UP8C@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Microvirus H protein (pilot protein) - - - - - - - - - - - - Microvir_H k59_90357_4 1286632.P278_33700 0.0 1035.0 28I9J@1|root,2Z8C8@2|Bacteria,4P06R@976|Bacteroidetes,1I7XB@117743|Flavobacteriia 976|Bacteroidetes S Bacteriophage replication gene A protein (GPA) - - - - - - - - - - - - Phage_GPA k59_90357_5 1270196.JCKI01000013_gene3202 4.42e-56 174.0 2AGWD@1|root,3174S@2|Bacteria 2|Bacteria S Phage protein C - - - - - - - - - - - - Phage_C k59_90357_6 1288298.rosmuc_01661 4.9e-103 298.0 28HVF@1|root,2Z81Q@2|Bacteria,1NZPF@1224|Proteobacteria 1224|Proteobacteria S Bacteriophage scaffolding protein D - - - - - - - - - - - - gpD k59_90357_7 1286632.P278_33670 1.35e-19 79.0 2EFW9@1|root,339NJ@2|Bacteria,4P71N@976|Bacteroidetes,1I6VT@117743|Flavobacteriia 976|Bacteroidetes S Microvirus J protein - - - - - - - - - - - - Microvir_J k59_265160_2 1692249.A0A0K1RL40_9CIRC 1.15e-67 218.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_248725_1 1117943.SFHH103_00150 1.05e-16 84.3 2DPZ1@1|root,3340X@2|Bacteria,1R2EE@1224|Proteobacteria,2TZIB@28211|Alphaproteobacteria,4BP2Q@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_99492_2 1327990.S0A384_9CAUD 1.92e-37 149.0 4QAW1@10239|Viruses,4QWUW@35237|dsDNA viruses no RNA stage,4QR8A@28883|Caudovirales,4QNCV@10744|Podoviridae 10744|Podoviridae S nucleic acid binding - - - - - - - - - - - - - k59_25577_2 1986029.Q9MBM6_9VIRU 1.91e-11 65.9 4QDBB@10239|Viruses,4QUM0@29258|ssDNA viruses,4QP4D@10841|Microviridae 10841|Microviridae S Chlamydia-phage Chp2 scaffold (Chlamy_scaf) - - - - - - - - - - - - - k59_216309_1 1234888.K0A2J2_9VIRU 9.28e-36 135.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_100196_1 145579.CAPSD_BPPHM 3.79e-100 313.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_50457_1 1247726.MIM_c10800 1.49e-19 92.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2VNHP@28216|Betaproteobacteria,3T3DM@506|Alcaligenaceae 28216|Betaproteobacteria S COG4626 Phage terminase-like protein, large subunit - - - - - - - - - - - - Terminase_1 k59_33981_1 347834.RHE_CH02994 7.56e-45 154.0 COG1442@1|root,COG1442@2|Bacteria,1QH4S@1224|Proteobacteria,2U2NZ@28211|Alphaproteobacteria,4BMMY@82115|Rhizobiaceae 28211|Alphaproteobacteria M glycosyl transferase family 8 - - - - - - - - - - - - - k59_9025_1 1379709.S5TMV0_9CIRC 1.94e-30 125.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_174584_1 1385935.N836_09470 6.21e-50 166.0 COG3728@1|root,COG3728@2|Bacteria,1G9S7@1117|Cyanobacteria 1117|Cyanobacteria L Small subunit - - - ko:K07474 - - - - ko00000 - - - Terminase_2 k59_116819_2 592316.Pat9b_2128 3.81e-105 340.0 COG5323@1|root,COG5410@1|root,COG5323@2|Bacteria,COG5410@2|Bacteria,1MW8S@1224|Proteobacteria,1SYQD@1236|Gammaproteobacteria,3W1VF@53335|Pantoea 1236|Gammaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6C k59_116819_3 90371.CY43_01855 4.33e-34 124.0 2BVDA@1|root,32QTA@2|Bacteria,1MYBS@1224|Proteobacteria,1S7PK@1236|Gammaproteobacteria 1236|Gammaproteobacteria S DNA-packaging protein gp3 - - - - - - - - - - - - GP3_package k59_116819_4 1317118.ATO8_19894 2.71e-08 59.7 2DR48@1|root,33A3G@2|Bacteria,1NN7E@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_116819_13 411470.RUMGNA_02049 1.79e-14 72.4 2C6KN@1|root,32Y69@2|Bacteria,1VANX@1239|Firmicutes,24MNG@186801|Clostridia,3Y12A@572511|Blautia 186801|Clostridia S VRR-NUC domain - - - - - - - - - - - - VRR_NUC k59_83586_1 1453501.JELR01000001_gene2559 1.68e-120 350.0 COG0582@1|root,COG0582@2|Bacteria,1QB64@1224|Proteobacteria,1RY8S@1236|Gammaproteobacteria,468CF@72275|Alteromonadaceae 1236|Gammaproteobacteria L Phage integrase family - - - - - - - - - - - - Arm-DNA-bind_1,Phage_int_SAM_4,Phage_integrase k59_166572_1 145579.CAPSD_BPPHM 1.4e-80 258.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_58686_2 94624.Bpet0946 3.45e-20 91.7 2AFFI@1|root,315FM@2|Bacteria,1PVIM@1224|Proteobacteria,2W4P2@28216|Betaproteobacteria,3T89N@506|Alcaligenaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_257863_1 160488.PP_2276 3.73e-45 155.0 COG0258@1|root,COG0258@2|Bacteria,1MYSI@1224|Proteobacteria,1SQ55@1236|Gammaproteobacteria 1236|Gammaproteobacteria L 5'-3' exonuclease, N-terminal resolvase-like domain - - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc_N k59_786_1 1415146.V5Q8Q5_9CAUD 7.29e-53 191.0 4QBMV@10239|Viruses,4QUU6@35237|dsDNA viruses no RNA stage,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_125229_1 56780.SYN_02235 2.47e-32 125.0 COG0305@1|root,COG0305@2|Bacteria 2|Bacteria L Participates in initiation and elongation during chromosome replication dnaG - 3.6.4.12 ko:K02314,ko:K02316 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - AAA_25,AAA_5,DUF2075,DnaB,DnaB_C,DnaB_bind,DnaG_DnaB_bind,Prim-Pol,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 k59_174588_1 1121267.JHZL01000027_gene1904 4.23e-20 94.7 COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,42MDZ@68525|delta/epsilon subdivisions,2YMJR@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,DnaGprimase_HBD,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 k59_83589_1 1317118.ATO8_19799 3.68e-33 133.0 COG0454@1|root,COG4678@1|root,COG0456@2|Bacteria,COG4678@2|Bacteria,1RJ9R@1224|Proteobacteria,2UB5V@28211|Alphaproteobacteria 28211|Alphaproteobacteria K acetyltransferase - - - - - - - - - - - - - k59_42182_1 204669.Acid345_3158 3.97e-12 66.6 28NSJ@1|root,2ZBRH@2|Bacteria,3Y8AG@57723|Acidobacteria,2JNAQ@204432|Acidobacteriia 204432|Acidobacteriia - - - - - - - - - - - - - - - k59_42182_3 278957.ABEA03000120_gene1182 1.78e-68 250.0 COG4733@1|root,COG4733@2|Bacteria,46YHY@74201|Verrucomicrobia,3K9MG@414999|Opitutae 414999|Opitutae S cellulase activity - - - - - - - - - - - - - k59_42182_6 1500890.JQNL01000001_gene3172 0.000111 50.1 COG3179@1|root,COG5153@1|root,COG3179@2|Bacteria,COG5153@2|Bacteria,1RC1P@1224|Proteobacteria,1RN66@1236|Gammaproteobacteria,1X5XS@135614|Xanthomonadales 135614|Xanthomonadales M Chitinase class I - - - ko:K03791 - - - - ko00000 - GH19 - Glyco_hydro_19,PG_binding_1,Peptidase_M23 k59_42182_16 1353537.TP2_16155 1.61e-126 386.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2TS19@28211|Alphaproteobacteria,2XN2A@285107|Thioclava 28211|Alphaproteobacteria F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrdZ - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_lgC,Ribonuc_red_lgN k59_207911_1 766499.C357_07046 6.51e-29 108.0 2CJ1K@1|root,2Z9CA@2|Bacteria,1R519@1224|Proteobacteria,2U28U@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_207911_2 1258572.M9PKE9_9CAUD 7.78e-63 196.0 4QAR6@10239|Viruses,4QUTK@35237|dsDNA viruses no RNA stage,4QPS2@28883|Caudovirales 28883|Caudovirales S dUTPase - GO:0003674,GO:0003824,GO:0004170,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0047429 - - - - - - - - - - - k59_141787_1 385682.AFSL01000060_gene1810 2.6e-19 84.7 COG0720@1|root,COG0720@2|Bacteria,4NM8H@976|Bacteroidetes,2FU4Q@200643|Bacteroidia,3XK4D@558415|Marinilabiliaceae 976|Bacteroidetes H 6-pyruvoyl tetrahydropterin synthase queD - 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 - - - PTPS k59_141787_2 457398.HMPREF0326_03160 2.75e-24 113.0 COG0467@1|root,COG4643@1|root,COG0467@2|Bacteria,COG4643@2|Bacteria,1RCH5@1224|Proteobacteria,42UIF@68525|delta/epsilon subdivisions,2WR54@28221|Deltaproteobacteria,2MHBQ@213115|Desulfovibrionales 28221|Deltaproteobacteria T AAA domain - - - ko:K06919 - - - - ko00000 - - - AAA_25,Toprim_3 k59_26574_1 5671.XP_001468508.1 5.39e-21 105.0 COG0749@1|root,KOG0950@2759|Eukaryota,3XSG4@5653|Kinetoplastida 5653|Kinetoplastida H Mitochondrial DNA polymerase I protein A POL1A - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - DNA_pol_A k59_59389_1 105154.Q9MBU6_9VIRU 2.54e-177 514.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_225480_1 1609634.A0A0C5ANA6_9VIRU 4.2e-09 61.6 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_167451_3 1385658.U5KPZ6_9VIRU 1.54e-182 528.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_17636_1 742159.HMPREF0004_1809 2.39e-20 92.4 COG3740@1|root,COG3740@2|Bacteria,1NHKT@1224|Proteobacteria,2VV07@28216|Betaproteobacteria,3T8GV@506|Alcaligenaceae 28216|Betaproteobacteria S Caudovirus prohead serine protease - - - ko:K06904 - - - - ko00000 - - - Peptidase_S78 k59_233400_2 1042209.HK44_020560 8.42e-135 397.0 2CYA9@1|root,32T3V@2|Bacteria,1RGRN@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_34723_8 1385658.U5KPZ6_9VIRU 7.44e-113 350.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_126049_1 1141519.H6VUA7_9CAUD 8.62e-31 128.0 4QBMV@10239|Viruses,4QUU6@35237|dsDNA viruses no RNA stage,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_126049_3 1028800.RG540_CH13650 3.84e-48 159.0 2E0FP@1|root,300A6@2|Bacteria,1PQHQ@1224|Proteobacteria,2V2WQ@28211|Alphaproteobacteria,4BJS5@82115|Rhizobiaceae 28211|Alphaproteobacteria L Phage endonuclease I - - - - - - - - - - - - Phage_endo_I k59_126049_6 935261.JAGL01000009_gene1165 1.19e-167 493.0 COG0209@1|root,COG0209@2|Bacteria,1PM78@1224|Proteobacteria,2UZUM@28211|Alphaproteobacteria,43QGW@69277|Phyllobacteriaceae 28211|Alphaproteobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides - - - - - - - - - - - - - k59_1716_1 2003327.REP_BPCHP 2.3e-06 57.0 4QCVK@10239|Viruses,4QUMV@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_1716_4 1234888.K0A2J2_9VIRU 5.26e-139 415.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_59476_2 365046.Rta_33080 5.83e-15 77.0 COG3405@1|root,COG3405@2|Bacteria,1QZE5@1224|Proteobacteria,2W62R@28216|Betaproteobacteria,4AIQV@80864|Comamonadaceae 28216|Betaproteobacteria G Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - - - - - - - - - - - k59_34794_1 10742.Q9MCU6_BPHK0 1.6e-33 143.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_34794_2 1109712.G9FHI3_9CAUD 1.24e-32 118.0 4QGG4@10239|Viruses,4QZ87@35237|dsDNA viruses no RNA stage,4QRCA@28883|Caudovirales,4QKMK@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_92748_1 1196095.GAPWK_2710 1.24e-10 72.0 COG3481@1|root,COG3481@2|Bacteria,1MUZY@1224|Proteobacteria,1RQUZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S relaxase traI - - - - - - - - - - - TraI_2,TraI_2_C k59_92748_2 83406.HDN1F_18220 1.27e-18 84.7 COG3266@1|root,COG3266@2|Bacteria,1MXMF@1224|Proteobacteria,1RRD8@1236|Gammaproteobacteria,1JBE6@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Integrating conjugative element protein PilL pilL - - ko:K02487 ko02020,map02020 M00507 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - TcpQ k59_168584_5 1307436.PBF_16639 4.31e-67 234.0 29SKA@1|root,30DRK@2|Bacteria,1UBKX@1239|Firmicutes,4IN15@91061|Bacilli,1ZMHH@1386|Bacillus 91061|Bacilli S Right handed beta helix region - - - - - - - - - - - - Beta_helix k59_168584_7 1121861.KB899916_gene1627 1.92e-155 469.0 COG4733@1|root,COG4733@2|Bacteria,1R7KR@1224|Proteobacteria,2TWI9@28211|Alphaproteobacteria,2JUCZ@204441|Rhodospirillales 204441|Rhodospirillales S Putative phage tail protein - - - - - - - - - - - - Phage-tail_3 k59_192710_1 1692255.A0A0K1RL52_9CIRC 3.2e-95 288.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_192710_2 1692252.A0A0K1RLN6_9CIRC 2.69e-23 105.0 4QCY8@10239|Viruses,4QUMD@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_192710_4 1618248.A0A0C5IB82_9CIRC 1.84e-33 124.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_218701_3 1441930.Z042_23145 6.14e-33 120.0 2D1MV@1|root,32TAZ@2|Bacteria,1N45A@1224|Proteobacteria,1S954@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage protein (N4 Gp49/phage Sf6 gene 66) family - - - - - - - - - - - - DUF2829,Phage_gp49_66 k59_135466_2 1161401.ASJA01000008_gene1655 2.78e-07 51.6 COG3567@1|root,COG3567@2|Bacteria,1QNPU@1224|Proteobacteria,2U19C@28211|Alphaproteobacteria 28211|Alphaproteobacteria S TIGRFAM phage-associated protein, HI1409 family - - - ko:K09961 - - - - ko00000 - - - DUF1073 k59_85006_1 1475143.W8SNN0_9CIRC 7.65e-37 144.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_168728_1 349521.HCH_04564 4.8e-06 50.1 COG3108@1|root,COG3108@2|Bacteria,1RICX@1224|Proteobacteria,1S6D5@1236|Gammaproteobacteria 1236|Gammaproteobacteria S peptidase M15 - - - ko:K17733 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M15_4 k59_250952_1 349521.HCH_05649 3.08e-26 114.0 COG4733@1|root,COG4733@2|Bacteria,1MXB4@1224|Proteobacteria,1RRUV@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Putative phage tail protein - - - - - - - - - - - - Phage-tail_3 k59_242873_1 1449338.JQLU01000005_gene1027 3.92e-09 65.1 COG3620@1|root,COG3620@2|Bacteria,1TPHQ@1239|Firmicutes,4HCHD@91061|Bacilli 91061|Bacilli K Replication initiation factor - - - ko:K07467 - - - - ko00000 - - - HTH_3,Rep_trans k59_192798_2 716928.AJQT01000109_gene1226 9.26e-63 198.0 COG3772@1|root,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,2U7RQ@28211|Alphaproteobacteria,4BAG3@82115|Rhizobiaceae 28211|Alphaproteobacteria G Phage lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_2948_1 1258572.M9PKE9_9CAUD 4.22e-13 67.0 4QAR6@10239|Viruses,4QUTK@35237|dsDNA viruses no RNA stage,4QPS2@28883|Caudovirales 28883|Caudovirales S dUTPase - GO:0003674,GO:0003824,GO:0004170,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0047429 - - - - - - - - - - - k59_2948_2 1123060.JONP01000001_gene1245 9.56e-63 215.0 COG1351@1|root,COG1351@2|Bacteria,1MWY8@1224|Proteobacteria,2TTER@28211|Alphaproteobacteria,2JQGP@204441|Rhodospirillales 204441|Rhodospirillales F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant thyX - 2.1.1.148 ko:K03465 ko00240,ko00670,ko01100,map00240,map00670,map01100 - R06613 RC00022,RC00332 ko00000,ko00001,ko01000 - - - Thy1 k59_2948_4 490913.C4NTB2_9CAUD 5.41e-23 89.7 4QF4C@10239|Viruses,4QXEM@35237|dsDNA viruses no RNA stage,4QST2@28883|Caudovirales,4QNFE@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_2948_5 490913.C4NTB3_9CAUD 1.43e-55 175.0 4QH70@10239|Viruses,4QYSD@35237|dsDNA viruses no RNA stage,4QTP3@28883|Caudovirales,4QNI1@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_2948_6 1477404.A0A023NGE5_9CAUD 9.51e-69 213.0 4QBG9@10239|Viruses,4QVK8@35237|dsDNA viruses no RNA stage,4QU8U@28883|Caudovirales,4QNH6@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_2948_7 1477404.A0A023NGK7_9CAUD 9.12e-77 233.0 4QE3S@10239|Viruses,4QX7A@35237|dsDNA viruses no RNA stage,4QSZ5@28883|Caudovirales,4QNI4@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_2948_8 1555208.A0A097EW10_9CAUD 0.000399 51.6 4QC60@10239|Viruses,4QPPD@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_60315_1 745776.DGo_CA1901 7.87e-39 150.0 COG1566@1|root,COG5280@1|root,COG1566@2|Bacteria,COG5280@2|Bacteria 2|Bacteria NT Phage tail tape measure protein TP901 - - - ko:K02005,ko:K02022 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_3,PhageMin_Tail k59_168730_1 644076.SCH4B_3106 6.68e-46 158.0 2EEQT@1|root,338IH@2|Bacteria,1NCP8@1224|Proteobacteria,2UHWI@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_135469_1 1618248.A0A0C5IB82_9CIRC 8.43e-100 302.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_259948_1 1123279.ATUS01000001_gene2720 2.53e-81 260.0 COG4128@1|root,COG4128@2|Bacteria,1RCY8@1224|Proteobacteria,1S4JQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Zonular occludens toxin (Zot) - - - ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko02042 - - - Zot k59_177932_1 935948.KE386495_gene2256 2.76e-06 48.9 COG3405@1|root,COG3405@2|Bacteria,1VBUA@1239|Firmicutes 1239|Firmicutes G Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - - - - - - - - - - - k59_251968_3 1145276.T479_19925 0.000567 49.7 COG5280@1|root,COG5412@1|root,COG5280@2|Bacteria,COG5412@2|Bacteria,1UWZ6@1239|Firmicutes,4I2HJ@91061|Bacilli,3IYXP@400634|Lysinibacillus 91061|Bacilli D Phage-related minor tail protein - - - - - - - - - - - - - k59_4511_2 428125.CLOLEP_01423 2.05e-16 79.7 2E2JP@1|root,32XP4@2|Bacteria,1VAIM@1239|Firmicutes,24PPR@186801|Clostridia,3WI4W@541000|Ruminococcaceae 186801|Clostridia S Phage tail protein - - - - - - - - - - - - Sipho_tail k59_111956_2 1408417.JHYB01000005_gene37 3.41e-101 315.0 COG0209@1|root,COG0209@2|Bacteria,3WSWN@544448|Tenericutes 544448|Tenericutes F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdE - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Flavodoxin_NdrI,RNR_N,Ribonuc_red_lgC,Ribonuc_red_lgN k59_19756_1 1276221.SDIMI_v3c05440 1.02e-10 64.3 COG0863@1|root,COG1092@1|root,COG0863@2|Bacteria,COG1092@2|Bacteria,3WV4X@544448|Tenericutes 544448|Tenericutes L DNA methylase - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_128825_1 1618258.A0A0C5I9K3_9CIRC 8.52e-09 63.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_61256_1 1788445.A0A190WHA3_9CIRC 1.02e-55 187.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_29080_1 1385658.U5KPZ6_9VIRU 7.53e-67 222.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_45657_2 1132026.I6NQT6_9CAUD 7.9e-30 125.0 4QEU0@10239|Viruses,4QTB3@28883|Caudovirales,4QM4I@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_45657_3 323848.Nmul_A1436 2.18e-08 63.2 2E3N6@1|root,32YKC@2|Bacteria,1NDBP@1224|Proteobacteria,2VXQM@28216|Betaproteobacteria,372YA@32003|Nitrosomonadales 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_220644_1 1506572.A0A097ZPG0_9CIRC 7.05e-25 104.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_194087_1 616991.JPOO01000001_gene4230 1.76e-35 139.0 COG3866@1|root,COG3866@2|Bacteria 2|Bacteria G Pectate lyase - - - - - - - - - - - - Pec_lyase_C k59_210591_3 521000.PROVRETT_05516 1.14e-14 75.9 2C9TR@1|root,317QU@2|Bacteria,1PZ3C@1224|Proteobacteria,1TE77@1236|Gammaproteobacteria,3Z9N5@586|Providencia 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_210591_4 492774.JQMB01000013_gene3025 2.41e-22 92.0 2AGTB@1|root,3171D@2|Bacteria,1RJGM@1224|Proteobacteria,2UJ68@28211|Alphaproteobacteria,4BHXG@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_204362_1 1121403.AUCV01000002_gene448 0.000107 54.3 COG4733@1|root,COG4932@1|root,COG5492@1|root,COG4733@2|Bacteria,COG4932@2|Bacteria,COG5492@2|Bacteria,1QW0V@1224|Proteobacteria,42U6C@68525|delta/epsilon subdivisions,2WQX8@28221|Deltaproteobacteria,2MN90@213118|Desulfobacterales 28221|Deltaproteobacteria M Parallel beta-helix repeats - - - - - - - - - - - - Beta_helix,Big_3_2,DUF4215 k59_79565_1 233412.HD_1569 6.6e-23 103.0 COG5281@1|root,COG5281@2|Bacteria,1MX2R@1224|Proteobacteria,1S3MM@1236|Gammaproteobacteria,1Y73U@135625|Pasteurellales 135625|Pasteurellales S tail length tape measure protein - - - - - - - - - - - - - k59_95675_1 1862825.A0A193CDY3_9VIRU 1.85e-29 112.0 4QB6C@10239|Viruses 10239|Viruses L Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_95675_2 1634487.A0A0E3M0E2_9VIRU 1.98e-48 169.0 4QB6C@10239|Viruses 10239|Viruses L Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_95675_3 1795989.A0A140CTP4_9VIRU 9.34e-12 68.9 4QAZA@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_79664_1 1161901.I1TLI4_9CAUD 5.18e-41 154.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_20920_1 1234888.K0A2R8_9VIRU 2.59e-44 155.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_211737_1 49964.Q94MS4_9CAUD 1.86e-103 326.0 4QCUF@10239|Viruses,4QV7U@35237|dsDNA viruses no RNA stage,4QQ89@28883|Caudovirales,4QNCY@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_62405_1 627192.SLG_22220 3.19e-27 131.0 COG4733@1|root,COG4733@2|Bacteria,1Q2WW@1224|Proteobacteria,2TUS9@28211|Alphaproteobacteria,2K24W@204457|Sphingomonadales 204457|Sphingomonadales S Phage-related protein, tail component - - - - - - - - - - - - Phage-tail_3 k59_62405_3 314264.ROS217_23412 2.33e-20 88.2 2DQY5@1|root,339C7@2|Bacteria,1PQ8Y@1224|Proteobacteria,2UGRV@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_171558_1 196162.Noca_1048 2.43e-40 144.0 COG4422@1|root,COG4422@2|Bacteria,2GJHQ@201174|Actinobacteria,4DQRH@85009|Propionibacteriales 201174|Actinobacteria S PFAM phage Gp37Gp68 family protein - - - - - - - - - - - - DUF5131 k59_179311_1 1676184.A0A186YBN5_9CIRC 1.58e-29 117.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_253267_1 145579.REP_BPPHM 2.01e-28 118.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_253267_3 1385658.U5KPZ6_9VIRU 1.44e-180 525.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_236527_3 525256.HMPREF0091_11228 2.1e-08 57.8 COG1403@1|root,COG1403@2|Bacteria,2IJEJ@201174|Actinobacteria 201174|Actinobacteria L HNH endonuclease - - - ko:K07451 - - - - ko00000,ko01000,ko02048 - - - HNH k59_113719_1 1168059.KB899087_gene2769 2.08e-09 68.2 COG0741@1|root,COG0741@2|Bacteria,1RJUN@1224|Proteobacteria 1224|Proteobacteria M lytic transglycosylase activity - - - - - - - - - - - - - k59_179312_1 1502724.FF80_03299 6.19e-06 48.1 COG0175@1|root,COG0175@2|Bacteria 2|Bacteria EH sulfate reduction - - - - - - - - - - - - PAPS_reduct k59_79666_2 1234888.K0A2J2_9VIRU 8.99e-137 409.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_87140_1 83344.XP_007932158.1 4.76e-37 142.0 COG0465@1|root,KOG0743@2759|Eukaryota,38CMD@33154|Opisthokonta,3NVKH@4751|Fungi,3QKI7@4890|Ascomycota,1ZXQD@147541|Dothideomycetes,3MFV2@451867|Dothideomycetidae 4751|Fungi O Belongs to the AAA ATPase family BCS1 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006810,GO:0006996,GO:0007005,GO:0007006,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017004,GO:0017062,GO:0017111,GO:0019866,GO:0022607,GO:0022857,GO:0022884,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032978,GO:0032979,GO:0033036,GO:0033108,GO:0033365,GO:0034551,GO:0034613,GO:0034622,GO:0042623,GO:0042886,GO:0042887,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0051131,GO:0051179,GO:0051204,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065003,GO:0070585,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0072594,GO:0072655,GO:0072657,GO:0090150,GO:1904680 - ko:K08900 - - - - ko00000,ko03029 - - - AAA,BCS1_N k59_55249_1 2003327.CAPSD_BPCHP 1.4e-20 95.1 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_132817_1 1385658.U5KPZ6_9VIRU 9.19e-150 443.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_107950_1 105154.Q9MBU6_9VIRU 2.52e-21 94.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_165945_1 1609634.A0A0C5AFV4_9VIRU 1.86e-75 247.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_149325_2 89187.ISM_05190 5.13e-16 85.5 COG5281@1|root,COG5281@2|Bacteria,1R47M@1224|Proteobacteria,2TUIV@28211|Alphaproteobacteria,46QA2@74030|Roseovarius 28211|Alphaproteobacteria S COG5281 Phage-related minor tail protein - - - - - - - - - - - - - k59_149325_18 1123269.NX02_21935 2.25e-38 152.0 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,2U6BJ@28211|Alphaproteobacteria,2K2MZ@204457|Sphingomonadales 204457|Sphingomonadales S Phage portal protein - - - - - - - - - - - - Phage_portal k59_149325_21 1237149.C900_05366 1.62e-10 67.4 COG3740@1|root,COG3740@2|Bacteria,4NDXV@976|Bacteroidetes,47V54@768503|Cytophagia 976|Bacteroidetes S Phage prohead protease, HK97 family - - - - - - - - - - - - Peptidase_S78 k59_149325_22 1121448.DGI_2056 2.54e-72 247.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,42QKN@68525|delta/epsilon subdivisions,2WK3R@28221|Deltaproteobacteria,2MA6M@213115|Desulfovibrionales 28221|Deltaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_240574_1 1234888.K0A2J2_9VIRU 7.02e-131 392.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_215733_1 1121459.AQXE01000001_gene2745 4.91e-13 75.1 COG3170@1|root,COG3170@2|Bacteria,1Q45C@1224|Proteobacteria,42Z4T@68525|delta/epsilon subdivisions,2WTRW@28221|Deltaproteobacteria,2MA4T@213115|Desulfovibrionales 28221|Deltaproteobacteria NU Tfp pilus assembly protein FimV - - - - - - - - - - - - - k59_33463_1 1385658.U5KPZ6_9VIRU 1.5e-41 151.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_8560_2 1089111.G8I7V8_9CAUD 3.33e-26 102.0 4QGDB@10239|Viruses,4QZHU@35237|dsDNA viruses no RNA stage,4QSG0@28883|Caudovirales,4QM88@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_182634_5 1453496.AT03_13275 3.46e-26 112.0 COG4834@1|root,COG4834@2|Bacteria,1MZ5H@1224|Proteobacteria,1SCQB@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2184) - - - - - - - - - - - - DUF2184 k59_17278_1 926560.KE387023_gene3164 7.04e-06 52.8 COG5263@1|root,COG5263@2|Bacteria 2|Bacteria S dextransucrase activity - - - - - - - - - - - - Big_2,CAP,CW_binding_1,GLTT,LRR_5,Mac-1,SLH k59_125461_4 1609634.A0A0C5AFT2_9VIRU 1.3e-125 370.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_125461_6 186617.M9M8L2_9VIRU 4.67e-47 164.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_58948_2 652103.Rpdx1_2535 9.19e-08 62.0 2DQ9V@1|root,335IH@2|Bacteria 2|Bacteria - - - - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - - k59_199884_1 69279.BG36_20805 1.83e-19 92.8 2AA25@1|root,30ZAV@2|Bacteria,1PM8F@1224|Proteobacteria,2UZVR@28211|Alphaproteobacteria,43QIT@69277|Phyllobacteriaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_150382_1 637730.C8XUH0_9CAUD 4.77e-80 249.0 4QAJD@10239|Viruses,4QW4M@35237|dsDNA viruses no RNA stage,4QQ7U@28883|Caudovirales,4QIAP@10662|Myoviridae 10662|Myoviridae S gp32 DNA binding protein like - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039686,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_1269_1 1609634.A0A0C5AFV4_9VIRU 4.95e-44 165.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_34346_2 115711.CP_0543 3.28e-08 57.8 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_233146_1 1158150.KB906242_gene233 1.16e-24 105.0 COG5410@1|root,COG5410@2|Bacteria,1N0W2@1224|Proteobacteria 1224|Proteobacteria K chromosome segregation - - - - - - - - - - - - - k59_67384_1 644076.SCH4B_3131 2.74e-24 94.4 2EQVT@1|root,33IFK@2|Bacteria,1NPA2@1224|Proteobacteria,2UU4I@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_67384_2 188350.Q8H9S6_9CAUD 3.51e-09 63.5 4QGE6@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_75769_1 1676988.A0A0H4FNQ1_9CIRC 2.82e-21 95.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_75769_3 1618241.A0A0C5I2I4_9CIRC 2.25e-59 193.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_83860_1 1234888.K0A2J2_9VIRU 1.22e-130 391.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_143379_1 1385658.U5KPZ6_9VIRU 3.02e-205 588.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_143379_2 1609634.A0A0C5ANA6_9VIRU 4.88e-09 62.4 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_151610_1 533240.CRC_01529 1.73e-82 250.0 COG0717@1|root,COG0717@2|Bacteria,1G2R2@1117|Cyanobacteria,1HMFP@1161|Nostocales 1117|Cyanobacteria F Belongs to the dCTP deaminase family dcd - 3.5.4.13 ko:K01494 ko00240,ko01100,map00240,map01100 M00053 R00568,R02325 RC00074 ko00000,ko00001,ko00002,ko01000 - - - dUTPase k59_126772_1 1463887.KL589975_gene5445 3.13e-17 84.0 COG0468@1|root,COG0468@2|Bacteria,2GJ4P@201174|Actinobacteria 201174|Actinobacteria L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA k59_209066_2 1986029.Q9MBM8_9VIRU 2.3e-50 175.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_168136_3 1379715.S5TMW6_9CIRC 0.000103 47.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_159336_2 1379707.S5SXZ4_9CIRC 1.89e-19 86.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_27278_1 1188256.BASI01000001_gene184 2.5e-08 60.1 COG0582@1|root,COG0582@2|Bacteria,1NH8M@1224|Proteobacteria,2TUHG@28211|Alphaproteobacteria,3FEGA@34008|Rhodovulum 28211|Alphaproteobacteria L Phage integrase family - - - - - - - - - - - - Phage_integrase k59_27278_5 548479.HMPREF0573_11260 2.35e-08 63.5 COG0749@1|root,COG0749@2|Bacteria,2IG0A@201174|Actinobacteria,4D4MC@85005|Actinomycetales 201174|Actinobacteria L DNA polymerase - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_27278_6 1229755.K7R6K3_9CAUD 2.82e-05 47.8 4QN92@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_2451_2 156889.Mmc1_1720 2.37e-72 246.0 28QU5@1|root,2ZD9H@2|Bacteria,1RAU8@1224|Proteobacteria,2UAGW@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_143385_1 1117108.PAALTS15_08369 2.69e-07 58.9 COG1216@1|root,COG1216@2|Bacteria,1V06G@1239|Firmicutes,4HGNC@91061|Bacilli,27638@186822|Paenibacillaceae 91061|Bacilli S Glycosyltransferase like family 2 - - - ko:K07011 - - - - ko00000 - - - Glycos_transf_2,Methyltransf_11,Methyltransf_23 k59_118643_1 1498011.A0A096XUV0_9CAUD 4.39e-21 90.1 4QAIU@10239|Viruses,4QPDE@28883|Caudovirales,4QNBQ@10744|Podoviridae 10744|Podoviridae S HNH endonuclease - - - - - - - - - - - - - k59_35215_3 1165094.RINTHH_3920 7.77e-61 202.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_35215_5 1385658.U5KPZ6_9VIRU 8.19e-85 270.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_259541_1 186617.M9M8L2_9VIRU 3.3e-130 385.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_201160_2 1609634.A0A0C5AFT2_9VIRU 5.03e-44 161.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_201160_4 105154.Q9MBU6_9VIRU 2.32e-179 523.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_85437_1 582402.Hbal_1563 1.81e-41 149.0 COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,2TRJX@28211|Alphaproteobacteria,43X2D@69657|Hyphomonadaceae 28211|Alphaproteobacteria M Belongs to the KdsA family kdsA - 2.5.1.55 ko:K01627 ko00540,ko01100,map00540,map01100 M00063 R03254 RC00435 ko00000,ko00001,ko00002,ko01000,ko01005 - - - DAHP_synth_1 k59_234793_1 192875.XP_004346780.1 1.03e-17 94.4 COG5108@1|root,KOG1038@2759|Eukaryota,38EAY@33154|Opisthokonta 33154|Opisthokonta KL mitochondrial transcription POLRMT GO:0000002,GO:0000428,GO:0000959,GO:0001018,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006351,GO:0006352,GO:0006390,GO:0006391,GO:0006725,GO:0006807,GO:0006996,GO:0007005,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0031974,GO:0032774,GO:0032991,GO:0034062,GO:0034245,GO:0034641,GO:0034645,GO:0034654,GO:0042645,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0061695,GO:0070013,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097659,GO:0097747,GO:0098798,GO:0140053,GO:0140098,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K10908 - - - - ko00000,ko01000,ko03029 - - - RNA_pol,RPOL_N k59_177320_1 696747.NIES39_J04450 1.62e-60 200.0 COG0338@1|root,COG0338@2|Bacteria,1G6KT@1117|Cyanobacteria,1HEEE@1150|Oscillatoriales 1117|Cyanobacteria L D12 class N6 adenine-specific DNA methyltransferase - - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 k59_44809_1 1126411.I1TEL3_9CIRC 1.92e-21 94.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_202289_3 313596.RB2501_01256 7.67e-05 42.7 COG3108@1|root,COG3108@2|Bacteria,4NV14@976|Bacteroidetes,1I63W@117743|Flavobacteriia 976|Bacteroidetes S Peptidase M15 - - - - - - - - - - - - Peptidase_M15_3 k59_36269_3 1420600.W5RNT1_9CIRC 7.09e-34 132.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_219951_1 1414739.W6AT00_9CAUD 1.88e-64 224.0 4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - GO:0008150,GO:0044403,GO:0044409,GO:0044411,GO:0044419,GO:0051701,GO:0051704,GO:0051828,GO:0051830,GO:0085027 - - - - - - - - - - - k59_85533_1 1609634.A0A0C5AFV4_9VIRU 1.2e-27 116.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_45006_1 115417.EPrPW00000022522 0.000468 48.5 2F0HQ@1|root,2T1P0@2759|Eukaryota 2759|Eukaryota - - - - - - - - - - - - - - - k59_69688_1 1475143.W8SNN0_9CIRC 3.12e-37 144.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_69688_2 1788444.A0A190WHB9_9CIRC 5.14e-61 201.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_111502_1 1449063.JMLS01000030_gene457 2.24e-15 83.6 COG3497@1|root,COG3497@2|Bacteria,1TPG4@1239|Firmicutes,4HCYP@91061|Bacilli,26UGB@186822|Paenibacillaceae 91061|Bacilli S phage tail - - - ko:K06907 - - - - ko00000 - - - - k59_11278_1 1618247.A0A0C5IMK7_9CIRC 2.3e-08 59.7 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_102802_2 1231190.NA8A_00010 2.86e-12 72.4 COG2755@1|root,COG2755@2|Bacteria 2|Bacteria E lipolytic protein G-D-S-L family - - - - - - - - - - - - Cadherin,Calx-beta,FG-GAP,Flg_new,Laminin_G_3,Lipase_GDSL_2,M60-like_N,PA14,Peptidase_M60 k59_94226_1 1618260.A0A0C5I2C5_9CIRC 5.64e-68 217.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_210160_1 360910.BAV0432 2.22e-35 153.0 COG3170@1|root,COG3170@2|Bacteria,1Q45C@1224|Proteobacteria,2W196@28216|Betaproteobacteria 28216|Betaproteobacteria NU Tfp pilus assembly protein FimV - - - - - - - - - - - - - k59_94227_1 428125.CLOLEP_01405 3.06e-44 148.0 2AIHK@1|root,318ZG@2|Bacteria,1V7P0@1239|Firmicutes,24KNU@186801|Clostridia,3WNH7@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_28716_1 1429794.A0A0A0Q0P2_9CAUD 6.52e-20 86.7 4QB0E@10239|Viruses,4QXJE@35237|dsDNA viruses no RNA stage,4QQU3@28883|Caudovirales,4QI46@10662|Myoviridae 10662|Myoviridae S Pyrimidine dimer DNA glycosylase - GO:0000704,GO:0003674,GO:0003824,GO:0003906,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0140097 - - - - - - - - - - - k59_203723_1 82995.CR62_24290 1.48e-68 225.0 COG5323@1|root,COG5410@1|root,COG5323@2|Bacteria,COG5410@2|Bacteria,1MW8S@1224|Proteobacteria,1SYQD@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6C k59_54558_1 113395.AXAI01000002_gene5442 6.45e-05 43.5 2FEUE@1|root,346TC@2|Bacteria,1MZPB@1224|Proteobacteria,2UC4Q@28211|Alphaproteobacteria,3K04T@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_211133_1 2003327.CAPSD_BPCHP 7.07e-20 96.7 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_12398_1 243090.RB6432 3.69e-10 63.5 COG2010@1|root,COG2755@1|root,COG5297@1|root,COG2010@2|Bacteria,COG2755@2|Bacteria,COG5297@2|Bacteria 2|Bacteria G Belongs to the glycosyl hydrolase family 6 - - 3.1.1.5 ko:K10804 ko01040,map01040 - - - ko00000,ko00001,ko01000,ko01004 - - - Alginate_lyase2,Lipase_GDSL_2 k59_170898_1 1120963.KB894501_gene316 7.88e-27 105.0 COG2852@1|root,COG2852@2|Bacteria,1N7EJ@1224|Proteobacteria,1SF5D@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - DUF559 k59_252660_1 349521.HCH_04541 3.07e-09 64.7 COG4733@1|root,COG4733@2|Bacteria,1R77Q@1224|Proteobacteria,1S1WT@1236|Gammaproteobacteria,1XMZT@135619|Oceanospirillales 135619|Oceanospirillales D Fibronectin type 3 domain - - - - - - - - - - - - - k59_228598_2 145579.H_BPPHM 5.24e-07 56.2 4QCA6@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_121008_5 105154.Q9MBU3_9VIRU 7.79e-17 82.4 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_121008_6 1609634.A0A0C5AFV4_9VIRU 3.22e-223 634.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_252661_1 1219035.NT2_13_00580 1.05e-22 99.8 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_261791_2 861360.AARI_30150 6.08e-07 55.5 COG0739@1|root,COG0741@1|root,COG0739@2|Bacteria,COG0741@2|Bacteria,2I8JC@201174|Actinobacteria,1W9CA@1268|Micrococcaceae 201174|Actinobacteria M Transglycosylase SLT domain - - - - - - - - - - - - Peptidase_M23,SLT k59_244450_2 582345.D6RRT1_BPKPP 9.24e-07 53.5 4QHHF@10239|Viruses,4QVRF@35237|dsDNA viruses no RNA stage,4QRG3@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_161795_1 691965.D4P7D6_9CAUD 1.54e-31 127.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_170908_1 1085623.GNIT_0959 7.54e-34 125.0 COG0582@1|root,COG0582@2|Bacteria,1P1R9@1224|Proteobacteria,1RRV0@1236|Gammaproteobacteria,467J2@72275|Alteromonadaceae 1236|Gammaproteobacteria L Phage integrase family - - - - - - - - - - - - Phage_integrase k59_187018_1 1417599.U6C7Z1_9CAUD 1.64e-60 204.0 4QD9Y@10239|Viruses,4QUXQ@35237|dsDNA viruses no RNA stage,4QTPE@28883|Caudovirales,4QNY4@10744|Podoviridae 10744|Podoviridae S Terminase-like family - - - - - - - - - - - - - k59_112825_3 1120960.ATXG01000010_gene2650 2.43e-05 48.5 COG0110@1|root,COG0110@2|Bacteria,2H5M0@201174|Actinobacteria,4FNDH@85023|Microbacteriaceae 201174|Actinobacteria S Hexapeptide repeat of succinyl-transferase wbpD - - - - - - - - - - - Hexapep,Hexapep_2 k59_12403_3 1219049.SP5_037_00250 1.64e-48 163.0 COG3926@1|root,COG3926@2|Bacteria,1MVXW@1224|Proteobacteria,2U8FG@28211|Alphaproteobacteria,2K3X0@204457|Sphingomonadales 204457|Sphingomonadales S secretion activating protein - - - - - - - - - - - - Glyco_hydro_108,PG_binding_3 k59_178652_3 1035191.HMPREF0185_01995 1.75e-26 107.0 COG4227@1|root,COG4227@2|Bacteria,1MU8I@1224|Proteobacteria,2TRIT@28211|Alphaproteobacteria,2KGTX@204458|Caulobacterales 204458|Caulobacterales L Domain of unknown function (DUF1738) - - - - - - - - - - - - DUF1738 k59_194661_3 1385658.U5KPZ6_9VIRU 9e-137 414.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_244537_1 1986029.Q9MBM3_9VIRU 4.73e-32 121.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_155745_2 649754.HMPREF0281_01830 3.12e-05 50.8 COG0749@1|root,COG4643@1|root,COG0749@2|Bacteria,COG4643@2|Bacteria,2I36D@201174|Actinobacteria,22MKB@1653|Corynebacteriaceae 201174|Actinobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity - - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - DNA_pol_A,DUF3854,Prim-Pol k59_55994_1 1538644.KO02_21560 9.2e-14 71.2 2DT8X@1|root,32UUQ@2|Bacteria,4NSYW@976|Bacteroidetes,1ITJW@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_237113_6 10704.B4UTR7_BP163 1.14e-27 107.0 4QAVB@10239|Viruses,4QVAN@35237|dsDNA viruses no RNA stage,4QQH3@28883|Caudovirales,4QKT9@10699|Siphoviridae 10699|Siphoviridae S chitin catabolic process - GO:0000270,GO:0001906,GO:0001907,GO:0005975,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009253,GO:0009605,GO:0009607,GO:0009617,GO:0016032,GO:0016052,GO:0019048,GO:0019058,GO:0019076,GO:0030203,GO:0031640,GO:0035821,GO:0035890,GO:0035891,GO:0039633,GO:0040011,GO:0043170,GO:0043207,GO:0044003,GO:0044004,GO:0044033,GO:0044035,GO:0044040,GO:0044041,GO:0044238,GO:0044278,GO:0044364,GO:0044403,GO:0044419,GO:0044659,GO:0044661,GO:0050896,GO:0051672,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0051818,GO:0051883,GO:0052126,GO:0052192,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - - - - - - - - - - - k59_237113_9 379329.Q08J70_9CAUD 1.51e-30 139.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QNG7@10744|Podoviridae 10744|Podoviridae S lytic transglycosylase activity - GO:0008150,GO:0016032,GO:0019058,GO:0030260,GO:0039678,GO:0044403,GO:0044409,GO:0044411,GO:0044419,GO:0046718,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0051830,GO:0085027 - - - - - - - - - - - k59_13645_1 575615.HMPREF0670_00650 6.31e-16 80.1 28NF9@1|root,2ZBHM@2|Bacteria,4NIQ4@976|Bacteroidetes,2FRJM@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_80327_1 690850.Desaf_3506 5.7e-14 72.4 2E645@1|root,330T3@2|Bacteria,1NEGX@1224|Proteobacteria,43352@68525|delta/epsilon subdivisions,2X1NK@28221|Deltaproteobacteria,2MFDF@213115|Desulfovibrionales 28221|Deltaproteobacteria S Holin of 3TMs, for gene-transfer release - - - - - - - - - - - - GTA_holin_3TM k59_139213_3 596151.DesfrDRAFT_0049 2.18e-08 63.5 COG3325@1|root,COG3325@2|Bacteria,1RKP7@1224|Proteobacteria,436KX@68525|delta/epsilon subdivisions,2X17Z@28221|Deltaproteobacteria,2MEFJ@213115|Desulfovibrionales 28221|Deltaproteobacteria G Belongs to the glycosyl hydrolase 18 family - - - - - - - - - - - - - k59_205529_1 273677.BW34_02782 1.81e-34 125.0 COG1351@1|root,COG1351@2|Bacteria,2HCNJ@201174|Actinobacteria,4FM61@85023|Microbacteriaceae 201174|Actinobacteria F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant thyX GO:0000166,GO:0003674,GO:0003824,GO:0004799,GO:0005488,GO:0008150,GO:0008152,GO:0008168,GO:0016740,GO:0016741,GO:0032259,GO:0036094,GO:0040007,GO:0042083,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050797,GO:0070402,GO:0097159,GO:1901265,GO:1901363 2.1.1.148 ko:K03465 ko00240,ko00670,ko01100,map00240,map00670,map01100 - R06613 RC00022,RC00332 ko00000,ko00001,ko01000 - - iNJ661.Rv2754c Thy1 k59_263390_1 1385658.U5KNR1_9VIRU 5.6e-46 161.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_122949_1 1123508.JH636441_gene3567 5.95e-09 64.3 2DSR5@1|root,33H51@2|Bacteria 1123508.JH636441_gene3567|- - - - - - - - - - - - - - - - k59_21903_1 525257.HMPREF0204_12939 9.59e-14 73.2 2DRAR@1|root,33AZK@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_172651_1 717785.HYPMC_1228 2.3e-08 57.4 2E6JI@1|root,3316K@2|Bacteria,1PP48@1224|Proteobacteria,2UT9Y@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_96604_2 2003327.CAPSD_BPCHP 6.72e-153 456.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_96604_5 1986029.Q9MBM3_9VIRU 2.4e-43 156.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_163340_1 1278309.KB907100_gene2353 3.29e-05 51.6 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1XI69@135619|Oceanospirillales 135619|Oceanospirillales L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_223206_1 1204521.I7A8M7_9CAUD 1.54e-59 212.0 4QCZC@10239|Viruses,4QX3V@35237|dsDNA viruses no RNA stage,4QRH3@28883|Caudovirales,4QHVR@10662|Myoviridae 10662|Myoviridae S Bacterial DNA polymerase III alpha subunit - - - - - - - - - - - - - k59_74134_3 314265.R2601_05343 6.58e-119 358.0 COG0754@1|root,COG0754@2|Bacteria,1MW6V@1224|Proteobacteria,2TU8J@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Glutathionylspermidine synthase MA20_09650 - - - - - - - - - - - GSP_synth k59_81986_1 864069.MicloDRAFT_00064220 1.35e-41 146.0 COG0863@1|root,COG0863@2|Bacteria,1R7RR@1224|Proteobacteria,2TS8Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - - - - - - - - - - - N6_N4_Mtase k59_157244_1 478749.BRYFOR_08524 2.85e-58 197.0 COG4626@1|root,COG4626@2|Bacteria,1TT9I@1239|Firmicutes,24AFK@186801|Clostridia 186801|Clostridia S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - Terminase_1 k59_206973_3 936580.HMPREF1516_0740 1.64e-41 153.0 28HHC@1|root,2Z7T2@2|Bacteria,1TR3B@1239|Firmicutes 1239|Firmicutes S AAA domain - - - - - - - - - - - - AAA_24 k59_206973_6 1530186.JQEY01000002_gene1537 1.96e-84 281.0 COG1061@1|root,COG1061@2|Bacteria,1MV9F@1224|Proteobacteria,2TUXC@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Type III restriction enzyme res subunit - - - ko:K19789 - - - - ko00000,ko03400 - - - DUF3427,HIT,Helicase_C,PLDc_2,ResIII,UPF0547 k59_140977_2 225937.HP15_1959 1.06e-22 98.6 2EFFY@1|root,3398P@2|Bacteria,1NCVZ@1224|Proteobacteria,1SFQ2@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Prophage minor tail protein Z (GPZ) - - - - - - - - - - - - Minor_tail_Z k59_181750_1 485914.Hmuk_1218 8.4e-12 64.3 COG1051@1|root,arCOG01075@2157|Archaea,2XYIN@28890|Euryarchaeota,23W6H@183963|Halobacteria 183963|Halobacteria L NUDIX domain - - - ko:K03207 - - - - ko00000,ko01000 - - - NUDIX k59_40195_3 56780.SYN_00585 4.3e-34 127.0 COG0451@1|root,COG0451@2|Bacteria,1MUGT@1224|Proteobacteria,42M12@68525|delta/epsilon subdivisions,2WIJX@28221|Deltaproteobacteria,2MQ3S@213462|Syntrophobacterales 28221|Deltaproteobacteria GM Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction fcl - 1.1.1.271 ko:K02377 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R05692 RC01014 ko00000,ko00001,ko01000 - - iAF987.Gmet_1312 Epimerase k59_106712_2 1385658.U5KQQ9_9VIRU 0.000126 50.4 4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_238989_1 316067.Geob_1408 0.000983 48.9 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2WJ3W@28221|Deltaproteobacteria,43TIJ@69541|Desulfuromonadales 28221|Deltaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_207135_1 742740.HMPREF9474_02278 4.9e-19 89.7 28JED@1|root,2Z98K@2|Bacteria,1TW1U@1239|Firmicutes,24CFD@186801|Clostridia,2226E@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - GerE k59_74343_1 1692257.A0A0K1RL39_9CIRC 1.59e-22 96.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_74343_2 1692262.A0A0K1RL89_9CIRC 5.02e-31 119.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_224019_4 1548905.A0A0A1IV55_9CAUD 1.13e-54 187.0 4QAUT@10239|Viruses,4QQ7X@28883|Caudovirales,4QKVS@10699|Siphoviridae 10699|Siphoviridae S DNA ligase (ATP) activity - - - - - - - - - - - - - k59_224019_16 360104.CCC13826_0268 2.72e-33 119.0 COG3179@1|root,COG3179@2|Bacteria,1NQ9X@1224|Proteobacteria,430FU@68525|delta/epsilon subdivisions,2YS2F@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria S D-alanyl-D-alanine carboxypeptidase - - - - - - - - - - - - Peptidase_M15_4 k59_224019_17 941449.dsx2_1524 1.92e-10 63.9 2BHPK@1|root,32BSU@2|Bacteria,1PZIG@1224|Proteobacteria,431P6@68525|delta/epsilon subdivisions,2WWV5@28221|Deltaproteobacteria,2MCBC@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_224019_24 1042876.PPS_2488 6.19e-06 60.1 COG1511@1|root,COG5185@1|root,COG1511@2|Bacteria,COG5185@2|Bacteria,1QV8Y@1224|Proteobacteria,1T2AE@1236|Gammaproteobacteria 1236|Gammaproteobacteria D tail protein - - - - - - - - - - - - TMP_2,Tape_meas_lam_C k59_279_1 502558.EGYY_19930 2.23e-18 93.2 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2GJY2@201174|Actinobacteria,4CUSF@84998|Coriobacteriia 84998|Coriobacteriia L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A k59_248946_3 160488.PP_2283 1.41e-25 105.0 2ATMD@1|root,31J5V@2|Bacteria,1RH31@1224|Proteobacteria,1SPN9@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Tail tubular protein - - - - - - - - - - - - Tube k59_248946_4 438753.AZC_3583 2.92e-18 94.4 28IA2@1|root,2Z8CQ@2|Bacteria,1PQM2@1224|Proteobacteria,2TUAP@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_182579_1 1563661.A0A097PAR0_9CAUD 9.77e-59 210.0 4QFFI@10239|Viruses,4QRHK@28883|Caudovirales,4QNX0@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_182579_2 490913.C4NTE2_9CAUD 7.01e-13 69.7 4QG5J@10239|Viruses,4QZ68@35237|dsDNA viruses no RNA stage,4QUEU@28883|Caudovirales,4QNKE@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_182579_3 349102.Rsph17025_0443 2.82e-13 77.0 2DKW9@1|root,30JFD@2|Bacteria,1QZ8U@1224|Proteobacteria,2U83R@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_49925_1 1692244.A0A0K1RLR5_9CIRC 2.8e-05 52.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_116311_1 49964.Q94MS4_9CAUD 1.34e-25 110.0 4QCUF@10239|Viruses,4QV7U@35237|dsDNA viruses no RNA stage,4QQ89@28883|Caudovirales,4QNCY@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_224025_1 532078.B3VCK6_9CAUD 1.08e-08 60.8 4QBAU@10239|Viruses,4QW8E@35237|dsDNA viruses no RNA stage,4QPEP@28883|Caudovirales,4QNY1@10744|Podoviridae 10744|Podoviridae S viral capsid assembly - - - - - - - - - - - - - k59_141111_1 1220714.L7TMV1_9CAUD 4.03e-43 155.0 4QEFV@10239|Viruses,4QYS7@35237|dsDNA viruses no RNA stage,4QRRT@28883|Caudovirales,4QJVQ@10662|Myoviridae 10662|Myoviridae S Pfam:Terminase_3C - - - - - - - - - - - - - k59_141111_2 754331.AEME01000001_gene6 7.49e-34 133.0 28JKJ@1|root,2Z9DD@2|Bacteria,1MUN2@1224|Proteobacteria,1RQIP@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage P22-like portal protein - - - - - - - - - - - - P22_portal k59_199210_10 1472912.A0A023NGT1_9CAUD 2.03e-64 224.0 4QAW1@10239|Viruses,4QWUW@35237|dsDNA viruses no RNA stage,4QR8A@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_141182_2 1692256.A0A0K1RL85_9CIRC 3.68e-117 345.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_25143_1 105154.Q9MBU6_9VIRU 2.19e-55 191.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_25143_3 1986029.Q9MBM6_9VIRU 2.05e-13 71.2 4QDBB@10239|Viruses,4QUM0@29258|ssDNA viruses,4QP4D@10841|Microviridae 10841|Microviridae S Chlamydia-phage Chp2 scaffold (Chlamy_scaf) - - - - - - - - - - - - - k59_8551_1 1168478.I6R9L9_9CAUD 5.3e-45 165.0 4QCHV@10239|Viruses,4QUW9@35237|dsDNA viruses no RNA stage,4QQEZ@28883|Caudovirales,4QMEA@10699|Siphoviridae 10699|Siphoviridae S Virulence-associated protein E - - - - - - - - - - - - - k59_132909_4 1406840.Q763_11510 2.09e-14 78.6 COG4675@1|root,COG4675@2|Bacteria,4NQJR@976|Bacteroidetes,1I31T@117743|Flavobacteriia,2NX1Q@237|Flavobacterium 976|Bacteroidetes S PFAM phage Tail Collar domain - - - - - - - - - - - - Collar k59_132909_8 1341151.ASZU01000008_gene1553 6.96e-08 60.5 COG3409@1|root,COG5632@1|root,COG3409@2|Bacteria,COG5632@2|Bacteria,1V7KT@1239|Firmicutes,4HJ9N@91061|Bacilli,27BVQ@186824|Thermoactinomycetaceae 91061|Bacilli M Ami_2 - - - - - - - - - - - - Amidase_2,DUF3597,PG_binding_1,SH3_5,SPOR k59_125304_2 759938.F5BSB4_9CIRC 2.01e-15 80.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_34057_2 1692244.A0A0K1RLR5_9CIRC 5.57e-92 280.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_9102_2 105154.Q9MBU6_9VIRU 2.99e-78 251.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_183232_3 1437448.AZRT01000014_gene1731 3e-08 54.3 2ERGC@1|root,33J1W@2|Bacteria,1NN9S@1224|Proteobacteria,2UKDV@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_183232_4 1380387.JADM01000008_gene942 2.23e-218 611.0 COG1783@1|root,COG1783@2|Bacteria,1MWGP@1224|Proteobacteria,1RMTH@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_183232_5 205918.Psyr_2793 1.23e-63 216.0 28KYW@1|root,2ZAE8@2|Bacteria,1MX3D@1224|Proteobacteria,1RQQR@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4055) - - - - - - - - - - - - DUF4055 k59_116997_1 674082.D1L2W3_9CAUD 2.91e-27 112.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QNI0@10744|Podoviridae 10744|Podoviridae S viral capsid - GO:0003674,GO:0005488,GO:0005515,GO:0042802 - - - - - - - - - - - k59_199825_2 1618238.A0A0C5IB41_9CIRC 2.63e-08 62.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_125389_2 504832.OCAR_7567 1.14e-30 138.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2TRJF@28211|Alphaproteobacteria,3JRVT@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_125389_5 97139.C824_03620 1.1e-12 76.6 COG0863@1|root,COG0863@2|Bacteria,1TRDZ@1239|Firmicutes,249ZT@186801|Clostridia 186801|Clostridia L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_125389_8 331678.Cphamn1_1726 4.09e-27 107.0 COG0847@1|root,COG0847@2|Bacteria,1FF0V@1090|Chlorobi 1090|Chlorobi L PFAM Exonuclease RNase T and DNA polymerase III - - - - - - - - - - - - RNase_T k59_216646_2 1144310.PMI07_002360 1.66e-05 50.1 2DPZ1@1|root,3340X@2|Bacteria,1R2EE@1224|Proteobacteria,2TZIB@28211|Alphaproteobacteria,4BP2Q@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_75566_2 1609634.A0A0C5AFT2_9VIRU 1.57e-112 334.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_75566_5 1609634.A0A0C5ANA6_9VIRU 4.23e-25 104.0 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_108686_1 142661.REP_CACV 1.02e-28 117.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_1044_2 1795993.A0A140CTQ1_9CIRC 5.8e-45 160.0 4QB6C@10239|Viruses,4QUKM@29258|ssDNA viruses 10239|Viruses J Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_259051_4 1201293.AKXQ01000048_gene1286 3.17e-25 100.0 2E645@1|root,330T3@2|Bacteria,1NEGX@1224|Proteobacteria,1SC3K@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Holin of 3TMs, for gene-transfer release - - - - - - - - - - - - GTA_holin_3TM k59_259051_6 1121373.KB903639_gene3773 1.04e-14 73.2 2DMPB@1|root,32SV8@2|Bacteria,4NSG4@976|Bacteroidetes,47SFC@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_259051_8 498211.CJA_0728 6.37e-51 169.0 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria,1FH39@10|Cellvibrio 1236|Gammaproteobacteria L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_259051_14 411468.CLOSCI_00315 1.6e-39 141.0 COG4712@1|root,COG4712@2|Bacteria,1V7HG@1239|Firmicutes,24GFS@186801|Clostridia 186801|Clostridia S double-strand break repair protein - - - - - - - - - - - - Rad52_Rad22 k59_259051_15 637910.ROD_03751 1.46e-25 104.0 COG1403@1|root,COG1403@2|Bacteria,1NE62@1224|Proteobacteria,1S9QW@1236|Gammaproteobacteria 1236|Gammaproteobacteria V HNH nucleases - - - - - - - - - - - - HNH k59_2042_2 644968.DFW101_3546 2.66e-21 90.1 2BICQ@1|root,32CIU@2|Bacteria,1Q6ZR@1224|Proteobacteria,43726@68525|delta/epsilon subdivisions,2X1TE@28221|Deltaproteobacteria,2MFN8@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_134567_1 573174.M4MBC1_9VIRU 6.29e-42 152.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage 10239|Viruses S N-methyltransferase activity - - - - - - - - - - - - - k59_34945_1 118173.KB235914_gene3829 8.65e-84 272.0 2DBP2@1|root,2ZA71@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_43349_2 1234888.K0A2J2_9VIRU 1.26e-66 220.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_159061_1 1470591.BW41_02766 3.55e-05 50.1 COG1609@1|root,COG1609@2|Bacteria,1NWPH@1224|Proteobacteria,2US0H@28211|Alphaproteobacteria,2K17J@204457|Sphingomonadales 204457|Sphingomonadales K Transcriptional regulator - - - - - - - - - - - - HTH_36 k59_167863_2 59689.fgenesh1_pm.C_scaffold_1003439 9.7e-11 67.4 2CM9Z@1|root,2QPRE@2759|Eukaryota,37M51@33090|Viridiplantae,3GCPS@35493|Streptophyta,3HZHT@3699|Brassicales 35493|Streptophyta - - - - - - - - - - - - - - - k59_242202_1 1244856.K4PWR8_9CAUD 6.38e-74 233.0 4QBA2@10239|Viruses,4QV98@35237|dsDNA viruses no RNA stage,4QPPI@28883|Caudovirales,4QP1B@10744|Podoviridae 10744|Podoviridae S Thymidylate synthase - - - - - - - - - - - - - k59_9934_1 1609634.A0A0C5AFV4_9VIRU 1.36e-44 161.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_184166_2 1986029.Q9MBM6_9VIRU 7.42e-24 98.2 4QDBB@10239|Viruses,4QUM0@29258|ssDNA viruses,4QP4D@10841|Microviridae 10841|Microviridae S Chlamydia-phage Chp2 scaffold (Chlamy_scaf) - - - - - - - - - - - - - k59_134705_1 105154.Q9MBT9_9VIRU 9.51e-08 50.8 4QCC5@10239|Viruses,4QUKW@29258|ssDNA viruses,4QP4C@10841|Microviridae 10841|Microviridae S viral process - - - - - - - - - - - - - k59_134705_2 1165094.RINTHH_3920 4.78e-17 84.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_217949_5 1556290.A0A0A0RSX5_9CAUD 1.26e-44 154.0 4QCAU@10239|Viruses,4QPJ6@28883|Caudovirales,4QKZJ@10699|Siphoviridae 10699|Siphoviridae S Pfam:GP88 - - - - - - - - - - - - - k59_225937_2 314264.ROS217_23412 1.06e-17 81.6 2DQY5@1|root,339C7@2|Bacteria,1PQ8Y@1224|Proteobacteria,2UGRV@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_17985_3 105154.Q9MBU6_9VIRU 9.73e-09 55.8 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_93028_1 1230476.C207_01166 7.53e-40 144.0 28PTM@1|root,2ZCEU@2|Bacteria,1R5DD@1224|Proteobacteria,2TVG7@28211|Alphaproteobacteria,3JU4C@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Family of unknown function (DUF5309) - - - - - - - - - - - - DUF5309 k59_93028_2 1524880.A0A076G697_9VIRU 5.03e-21 98.6 4QD1M@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_208885_2 1234888.K0A2J2_9VIRU 9.53e-149 440.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_201940_1 145579.CAPSD_BPPHM 9.39e-13 69.3 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_93860_4 1234888.K0A2J2_9VIRU 1.01e-57 199.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_185244_1 1234888.K0A2J2_9VIRU 1.25e-109 337.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_110987_1 1234888.K0A2J2_9VIRU 8.07e-118 361.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_44464_3 768066.HELO_1265 8.55e-43 147.0 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria,1XJHS@135619|Oceanospirillales 135619|Oceanospirillales L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_69219_8 666681.M301_0132 4.43e-46 173.0 2D784@1|root,32TNH@2|Bacteria,1N098@1224|Proteobacteria,2VX0M@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_60594_3 1321778.HMPREF1982_04640 1.14e-10 58.5 COG1694@1|root,COG1694@2|Bacteria,1VIQA@1239|Firmicutes,24SKH@186801|Clostridia 186801|Clostridia S MazG nucleotide pyrophosphohydrolase - - - - - - - - - - - - MazG k59_112133_1 3218.PP1S241_95V6.1 2.19e-25 110.0 COG5108@1|root,KOG1038@2759|Eukaryota,37Q9S@33090|Viridiplantae,3G82K@35493|Streptophyta 35493|Streptophyta K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates - GO:0000428,GO:0000959,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006351,GO:0006390,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009536,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034245,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0098798,GO:0140053,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K10908 - - - - ko00000,ko01000,ko03029 - - - RNA_pol,RPOL_N k59_78604_1 1618242.A0A0C5IBR9_9CIRC 1.33e-32 126.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_170246_1 999549.KI421514_gene23 6.1e-23 99.4 COG0582@1|root,COG0582@2|Bacteria,1Q7U1@1224|Proteobacteria,2U52B@28211|Alphaproteobacteria,282DP@191028|Leisingera 28211|Alphaproteobacteria L Phage integrase family - - - - - - - - - - - - Phage_integrase k59_61369_3 348824.LPU83_1512 2.54e-17 85.9 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2TSDW@28211|Alphaproteobacteria,4BCQ8@82115|Rhizobiaceae 28211|Alphaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_19874_4 1385658.U5KNR1_9VIRU 7.7e-73 233.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_120493_1 316407.85674673 0.000102 49.7 COG0582@1|root,COG0582@2|Bacteria,1MWBN@1224|Proteobacteria,1RPD0@1236|Gammaproteobacteria,3XN2J@561|Escherichia 1236|Gammaproteobacteria L Integrase from the cryptic lambdoic prophage DLP12. Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome intD GO:0000150,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0008979,GO:0009009,GO:0009987,GO:0015074,GO:0016032,GO:0019042,GO:0019043,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051704,GO:0071704,GO:0075713,GO:0090304,GO:0140097,GO:1901360 - - - - - - - - - - Phage_integrase k59_78682_1 1121897.AUGO01000006_gene817 1.89e-22 89.4 2AA1U@1|root,30ZAH@2|Bacteria,4PDG8@976|Bacteroidetes,1INFP@117743|Flavobacteriia,2NZG4@237|Flavobacterium 976|Bacteroidetes - - - - - - - - - - - - - - - k59_61425_1 641491.DND132_1955 1.21e-16 84.7 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,42Z58@68525|delta/epsilon subdivisions,2WTW4@28221|Deltaproteobacteria,2M8HG@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_161359_1 1085623.GNIT_1814 4.95e-30 120.0 2CYA9@1|root,32T3V@2|Bacteria,1RGRN@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_70302_1 1122201.AUAZ01000026_gene1170 4.72e-31 117.0 COG4128@1|root,COG4128@2|Bacteria,1REHG@1224|Proteobacteria,1S491@1236|Gammaproteobacteria,46BRE@72275|Alteromonadaceae 1236|Gammaproteobacteria S Zonular occludens toxin (Zot) - - - - - - - - - - - - Zot k59_11953_1 1524880.A0A076G7N6_9VIRU 9.74e-32 131.0 4QAUF@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_11953_2 1524880.A0A076G6J2_9VIRU 2.76e-155 453.0 4QD9Y@10239|Viruses 10239|Viruses S Pfam:Terminase_6C - - - - - - - - - - - - - k59_4790_1 225937.HP15_3095 5.63e-89 274.0 COG4128@1|root,COG4128@2|Bacteria,1N0I7@1224|Proteobacteria,1SAH8@1236|Gammaproteobacteria,46BMP@72275|Alteromonadaceae 1236|Gammaproteobacteria S Zonular occludens toxin (Zot) zot GO:0001906,GO:0006810,GO:0006996,GO:0007010,GO:0008150,GO:0009405,GO:0009987,GO:0016043,GO:0031640,GO:0035821,GO:0042044,GO:0042045,GO:0044364,GO:0044419,GO:0051179,GO:0051234,GO:0051704,GO:0070633,GO:0071840 - ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko02042 - - - Zot k59_194169_3 322855.Q52PP4_9CAUD 5.88e-61 204.0 4QAUT@10239|Viruses,4QVIM@35237|dsDNA viruses no RNA stage,4QQ7X@28883|Caudovirales 28883|Caudovirales S DNA ligase (ATP) activity - - - - - - - - - - - - - k59_136965_1 637390.AFOH01000046_gene2123 0.000485 47.0 COG0741@1|root,COG0741@2|Bacteria,1RHFF@1224|Proteobacteria,1S8IF@1236|Gammaproteobacteria,2NDDU@225057|Acidithiobacillales 225057|Acidithiobacillales M Transglycosylase SLT domain - - - - - - - - - - - - SLT k59_86109_2 1385658.U5KPZ6_9VIRU 3.88e-06 51.2 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_20874_2 1158762.KB898038_gene1905 1.67e-20 103.0 COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,1R97W@1224|Proteobacteria 1224|Proteobacteria D Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_171516_3 1121935.AQXX01000130_gene2451 2.73e-26 102.0 COG2916@1|root,COG2916@2|Bacteria,1RASP@1224|Proteobacteria,1SU1W@1236|Gammaproteobacteria 1236|Gammaproteobacteria D ftsk spoiiie - - - - - - - - - - - - - k59_6010_4 114615.BRADO2879 8.81e-11 63.5 COG2520@1|root,COG2520@2|Bacteria,1RIYU@1224|Proteobacteria,2U2ZF@28211|Alphaproteobacteria,3JSC4@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Methyltransferase FkbM domain - - - - - - - - - - - - Methyltransf_21 k59_162432_1 438753.AZC_3588 4.66e-119 366.0 28MSK@1|root,2ZB0X@2|Bacteria,1R7CY@1224|Proteobacteria,2U2MY@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_113664_2 1121382.JQKG01000006_gene3566 1.73e-24 97.4 COG2852@1|root,COG2852@2|Bacteria 2|Bacteria L Protein conserved in bacteria - - 2.1.1.72 ko:K07316 - - - - ko00000,ko01000,ko02048 - - - - k59_55202_1 1692247.A0A0K1RL30_9CIRC 4.09e-08 55.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_253245_1 136993.KB900626_gene2736 4.45e-23 100.0 COG3723@1|root,COG3723@2|Bacteria,1R6DB@1224|Proteobacteria,2U82T@28211|Alphaproteobacteria 28211|Alphaproteobacteria L RecT family - - - ko:K07455 - - - - ko00000,ko03400 - - - RecT k59_37816_2 113395.AXAI01000008_gene1139 4.32e-06 52.8 COG3551@1|root,COG3551@2|Bacteria,1RB2G@1224|Proteobacteria,2U7MV@28211|Alphaproteobacteria 28211|Alphaproteobacteria D Protein conserved in bacteria - - - - - - - - - - - - Sulfotransfer_3 k59_21007_4 1306990.BARG01000038_gene4650 0.000706 43.9 COG1396@1|root,COG1396@2|Bacteria,2I4FJ@201174|Actinobacteria 201174|Actinobacteria K Cupin 2, conserved barrel domain protein - - - - - - - - - - - - Cupin_2,HTH_3,HTH_31 k59_148508_6 1498011.A0A096XUS7_9CAUD 7.07e-31 136.0 4QAUF@10239|Viruses,4QQIV@28883|Caudovirales,4QNZ6@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_172972_2 2003327.CAPSD_BPCHP 2.14e-53 186.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_163592_1 691965.D4P7I3_9CAUD 7.38e-119 383.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_163592_2 665950.HMPREF1025_01958 9.03e-27 105.0 2E0G5@1|root,32W28@2|Bacteria,1VAS0@1239|Firmicutes,24NYA@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_163592_3 1537917.JU82_03700 2.24e-47 164.0 COG0553@1|root,COG0553@2|Bacteria 2|Bacteria L helicase activity - - - - - - - - - - - - Helicase_C,PLDc_2,ResIII,SNF2_N k59_7586_1 1034769.KB910518_gene93 9.01e-06 54.3 2DU1R@1|root,33NJD@2|Bacteria,1VNU1@1239|Firmicutes,4IUIJ@91061|Bacilli,26UV9@186822|Paenibacillaceae 91061|Bacilli - - - - - - - - - - - - - - - k59_123195_1 1692242.A0A0K1RKZ2_9CIRC 5.95e-15 77.4 4QFEW@10239|Viruses,4QUKZ@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_123195_2 1692242.A0A0K1RL37_9CIRC 4.97e-86 266.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_196408_1 644966.Tmar_0036 9.11e-65 211.0 COG5323@1|root,COG5323@2|Bacteria 2|Bacteria M Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_230369_4 1220601.L7TJ83_9CAUD 1.32e-53 179.0 4QHD0@10239|Viruses,4QXZW@35237|dsDNA viruses no RNA stage,4QUGC@28883|Caudovirales 28883|Caudovirales S T=7 icosahedral viral capsid - GO:0003674,GO:0005488,GO:0005515,GO:0042802 - - - - - - - - - - - k59_22233_1 1304275.C41B8_05358 7.08e-19 84.3 2DR0J@1|root,32UQ6@2|Bacteria,1N448@1224|Proteobacteria,1SPZ3@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_156244_2 466051.A7XX47_9CAUD 3.8e-19 88.6 4QAUS@10239|Viruses,4QURX@35237|dsDNA viruses no RNA stage,4QQ2S@28883|Caudovirales,4QKRA@10699|Siphoviridae 10699|Siphoviridae S flavin adenine dinucleotide binding - - - - - - - - - - - - - k59_56478_1 1345023.M467_13815 3.79e-10 66.2 COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,4H9T3@91061|Bacilli,3WE65@539002|Bacillales incertae sedis 91061|Bacilli L DNA polymerase dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k59_63461_3 1692244.A0A0K1RLR5_9CIRC 2.5e-19 95.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_14126_1 438753.AZC_3597 1.47e-95 301.0 COG0749@1|root,COG0749@2|Bacteria,1P27P@1224|Proteobacteria,2TVEI@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DNA polymerase family A - - - - - - - - - - - - DNA_pol_A k59_246042_1 1121935.AQXX01000096_gene2550 1.03e-24 103.0 COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,1MVH7@1224|Proteobacteria,1S09Z@1236|Gammaproteobacteria,1XP1M@135619|Oceanospirillales 135619|Oceanospirillales KL DNA methylase - - - - - - - - - - - - N6_N4_Mtase,ParBc k59_246042_2 713605.ADHG01000003_gene727 0.000119 48.5 COG2963@1|root,COG2963@2|Bacteria,1V6XW@1239|Firmicutes,4HIUS@91061|Bacilli,3F7DT@33958|Lactobacillaceae 91061|Bacilli L transposase activity - - - - - - - - - - - - HTH_23 k59_105896_1 1121451.DESAM_22831 3.56e-13 73.2 2DNU8@1|root,32Z5M@2|Bacteria,1NARQ@1224|Proteobacteria,432SD@68525|delta/epsilon subdivisions,2WY7K@28221|Deltaproteobacteria,2MD12@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_230478_1 1090318.ATTI01000001_gene981 3.17e-10 68.2 2ES2P@1|root,33JMP@2|Bacteria,1NGYH@1224|Proteobacteria,2UMK8@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_14239_1 1121033.AUCF01000004_gene4632 1.07e-06 57.4 COG2227@1|root,COG2227@2|Bacteria,1RAQ6@1224|Proteobacteria,2U62S@28211|Alphaproteobacteria,2JWU8@204441|Rhodospirillales 204441|Rhodospirillales H Methyltransferase domain - - - - - - - - - - - - Methyltransf_23 k59_180712_1 1500301.JQMF01000006_gene1767 6.89e-23 96.7 2AFZH@1|root,3163D@2|Bacteria,1RJUP@1224|Proteobacteria,2UI0N@28211|Alphaproteobacteria,4BK5T@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_254520_4 316067.Geob_2947 1.82e-08 57.0 COG4932@1|root,COG4932@2|Bacteria 2|Bacteria M domain protein - - 2.4.1.9 ko:K20811 ko00500,map00500 - R04194 RC00077,RC00247 ko00000,ko00001,ko01000 - GH68 - Cna_B,FctA,Gram_pos_anchor,MucBP,SdrD_B,YSIRK_signal k59_246146_1 1234879.K0A1L0_9CIRC 4.84e-18 88.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_88021_2 1618251.A0A0C5I2L8_9CIRC 1.01e-29 116.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_23336_1 1609634.A0A0C5AFV4_9VIRU 1.43e-09 58.5 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_190694_1 1461694.ATO9_10110 5.63e-26 98.2 COG3750@1|root,COG3750@2|Bacteria,1N77J@1224|Proteobacteria,2UFX6@28211|Alphaproteobacteria,2PEIQ@252301|Oceanicola 28211|Alphaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2312) - - - - - - - - - - - - DUF2312 k59_231404_2 1120963.KB894501_gene316 2.5e-25 100.0 COG2852@1|root,COG2852@2|Bacteria,1N7EJ@1224|Proteobacteria,1SF5D@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - DUF559 k59_116079_1 225937.HP15_3095 8.23e-57 197.0 COG4128@1|root,COG4128@2|Bacteria,1N0I7@1224|Proteobacteria,1SAH8@1236|Gammaproteobacteria,46BMP@72275|Alteromonadaceae 1236|Gammaproteobacteria S Zonular occludens toxin (Zot) zot GO:0001906,GO:0006810,GO:0006996,GO:0007010,GO:0008150,GO:0009405,GO:0009987,GO:0016043,GO:0031640,GO:0035821,GO:0042044,GO:0042045,GO:0044364,GO:0044419,GO:0051179,GO:0051234,GO:0051704,GO:0070633,GO:0071840 - ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko02042 - - - Zot k59_97787_1 1618260.A0A0C5I2C5_9CIRC 1.24e-35 132.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_206902_3 1385658.U5KPZ6_9VIRU 7.92e-178 518.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_81913_1 1234888.K0A2J2_9VIRU 1.32e-120 367.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_106654_6 105154.Q9MBU6_9VIRU 9.57e-172 504.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_40099_1 1618248.A0A0C5IB82_9CIRC 6.49e-14 71.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_132514_2 556268.OFAG_02256 3.72e-41 141.0 2A24E@1|root,30QER@2|Bacteria,1NZ1I@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_132514_3 157783.LK03_14840 2.27e-15 74.7 COG3206@1|root,COG3206@2|Bacteria,1ND5H@1224|Proteobacteria,1RNXC@1236|Gammaproteobacteria 1236|Gammaproteobacteria M DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease - - - - - - - - - - - - Rad52_Rad22 k59_132514_4 1218352.B597_019610 2.48e-28 111.0 COG3206@1|root,COG3206@2|Bacteria,1ND5H@1224|Proteobacteria,1RNXC@1236|Gammaproteobacteria 1236|Gammaproteobacteria M DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease - - - - - - - - - - - - Rad52_Rad22 k59_181696_2 105154.Q9MBU6_9VIRU 1.7e-174 511.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_181697_1 2003327.CAPSD_BPCHP 2.82e-17 86.7 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_181701_2 575589.HMPREF0018_02858 2.2e-47 160.0 COG1961@1|root,COG1961@2|Bacteria,1R3XB@1224|Proteobacteria,1RSC2@1236|Gammaproteobacteria,3NNJ2@468|Moraxellaceae 1236|Gammaproteobacteria L Resolvase, N terminal domain - - - - - - - - - - - - Resolvase k59_132528_2 585.DR95_513 6.99e-63 207.0 28JXH@1|root,2Z9MZ@2|Bacteria,1MXNC@1224|Proteobacteria,1RNI6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S RecT family STY2074 - - - - - - - - - - - RecT k59_64496_2 156889.Mmc1_1558 1.87e-13 71.6 COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,2TRJX@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Belongs to the KdsA family kdsA - 2.5.1.55 ko:K01627 ko00540,ko01100,map00540,map01100 M00063 R03254 RC00435 ko00000,ko00001,ko00002,ko01000,ko01005 - - - DAHP_synth_1 k59_213964_2 1123072.AUDH01000035_gene1395 4.54e-47 161.0 28NSJ@1|root,2ZBRH@2|Bacteria,1RAXM@1224|Proteobacteria,2U60W@28211|Alphaproteobacteria,2JU5F@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - k59_213964_3 658401.C7F4B8_9CAUD 2.12e-06 55.5 4QH5W@10239|Viruses,4QYFG@35237|dsDNA viruses no RNA stage,4QQD8@28883|Caudovirales,4QN2T@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_57593_3 1122244.AUGF01000006_gene1474 0.000435 42.0 COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,1S5V7@1236|Gammaproteobacteria,3NNIS@468|Moraxellaceae 1236|Gammaproteobacteria J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation rplL GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0046983,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02935 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L12,Ribosomal_L12_N k59_198891_1 861047.E0YPM6_9CAUD 9.4e-14 71.6 4QARC@10239|Viruses,4QV4E@35237|dsDNA viruses no RNA stage,4QPDS@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_215280_3 44088.Q6VZJ4_CNPV 6.23e-08 55.5 4QB1C@10239|Viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_256929_1 160488.PP_2284 1.37e-31 134.0 28IA2@1|root,2Z8CQ@2|Bacteria,1PQM2@1224|Proteobacteria,1SN3W@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_107480_1 698761.RTCIAT899_CH11730 3.57e-23 118.0 COG4733@1|root,COG4733@2|Bacteria,1Q2WW@1224|Proteobacteria,2TUS9@28211|Alphaproteobacteria,4B9ZW@82115|Rhizobiaceae 28211|Alphaproteobacteria S Phage-related protein, tail component - - - - - - - - - - - - DUF1983,Phage-tail_3 k59_107480_7 471881.PROPEN_00214 2.09e-32 119.0 COG3108@1|root,COG3108@2|Bacteria,1RICX@1224|Proteobacteria,1S6D5@1236|Gammaproteobacteria,3Z3EN@583|Proteus 1236|Gammaproteobacteria S D-alanyl-D-alanine carboxypeptidase - - - ko:K17733 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M15_4 k59_265064_3 1165094.RINTHH_3920 1e-74 238.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_265064_5 105154.Q9MBU3_9VIRU 4.7e-16 80.1 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_265064_6 1385658.U5KPZ6_9VIRU 4.42e-184 531.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_107487_1 1609634.A0A0C5AFT2_9VIRU 8.6e-52 175.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_224664_3 311402.Avi_2984 6.45e-28 130.0 COG4733@1|root,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria,2TV2W@28211|Alphaproteobacteria,4BIQV@82115|Rhizobiaceae 28211|Alphaproteobacteria S COG4733 Phage-related protein, tail component - - - - - - - - - - - - Phage-tail_3 k59_9078_1 411460.RUMTOR_01335 1.39e-72 246.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_42244_1 742725.HMPREF9450_01668 2.29e-61 211.0 COG0305@1|root,COG0305@2|Bacteria,4NF8P@976|Bacteroidetes,2FNG7@200643|Bacteroidia,22UPI@171550|Rikenellaceae 976|Bacteroidetes L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_116864_18 223283.PSPTO_3416 1.9e-12 65.1 2DQAD@1|root,335M3@2|Bacteria,1QV8I@1224|Proteobacteria,1T29X@1236|Gammaproteobacteria,1Z7XP@136849|Pseudomonas syringae group 1236|Gammaproteobacteria S Phage holin family (Lysis protein S) - - - - - - - - - - - - Phage_holin_3_1 k59_58878_1 428125.CLOLEP_01409 2.15e-68 224.0 COG4626@1|root,COG4626@2|Bacteria,1TT9I@1239|Firmicutes,24AFK@186801|Clostridia,3WNF4@541000|Ruminococcaceae 186801|Clostridia S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_258123_1 1795993.A0A140CTQ1_9CIRC 3.63e-32 121.0 4QB6C@10239|Viruses,4QUKM@29258|ssDNA viruses 10239|Viruses J Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_166746_2 279383.Q5DN17_9CAUD 0.00084 51.6 4QBUC@10239|Viruses,4QVRG@35237|dsDNA viruses no RNA stage,4QQGQ@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_150207_3 948071.S4S2M5_9CAUD 3.3e-122 363.0 4QBD3@10239|Viruses,4QXFU@35237|dsDNA viruses no RNA stage,4QQ7Z@28883|Caudovirales,4QNS1@10744|Podoviridae 10744|Podoviridae S viral capsid - - - - - - - - - - - - - k59_34145_2 426117.M446_3418 6.44e-57 204.0 COG1061@1|root,COG1061@2|Bacteria,1MV9F@1224|Proteobacteria,2TUXC@28211|Alphaproteobacteria,1JTIG@119045|Methylobacteriaceae 28211|Alphaproteobacteria L DEAD DEAH box helicase domain protein - - - ko:K19789 - - - - ko00000,ko03400 - - - DUF3427,HIT,Helicase_C,PLDc_2,ResIII,UPF0547 k59_232971_1 1131315.H2DE57_9CAUD 1.03e-41 176.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QNG7@10744|Podoviridae 10744|Podoviridae S lytic transglycosylase activity - GO:0008150,GO:0016032,GO:0019058,GO:0030260,GO:0039678,GO:0044403,GO:0044409,GO:0044411,GO:0044419,GO:0046718,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0051830,GO:0085027 - - - - - - - - - - - k59_232971_3 179237.Q8W6K8_9CAUD 7.77e-40 160.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales 28883|Caudovirales S N-acetylmuramoyl-L-alanine amidase activity - - - - - - - - - - - - - k59_232971_4 242527.Q6V7M4_9CAUD 3.23e-51 166.0 4QGY0@10239|Viruses,4QWBI@35237|dsDNA viruses no RNA stage,4QR52@28883|Caudovirales 28883|Caudovirales S transferase activity, transferring acyl groups - - - - - - - - - - - - - k59_232971_6 351016.RAZWK3B_16680 4.76e-139 421.0 291GM@1|root,2ZP3A@2|Bacteria,1RD1E@1224|Proteobacteria,2UPJH@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_232971_8 1273711.A0A096VKG4_9CAUD 3.7e-35 154.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QNBD@10744|Podoviridae 10744|Podoviridae S outer membrane - - - - - - - - - - - - - k59_232971_13 1500257.JQNM01000006_gene1744 1.43e-27 112.0 2CABR@1|root,32TG1@2|Bacteria,1N041@1224|Proteobacteria,2USA1@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_232971_15 107636.JQNK01000008_gene4011 4.87e-11 64.3 2DF22@1|root,2ZQ6A@2|Bacteria,1P591@1224|Proteobacteria,2UX05@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_232971_16 107636.JQNK01000008_gene4012 2.09e-179 509.0 28MVD@1|root,2ZB2Y@2|Bacteria,1R8NK@1224|Proteobacteria,2U265@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF4043) - - - - - - - - - - - - DUF4043 k59_259218_2 1475143.W8SNN0_9CIRC 2.84e-23 104.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_225951_1 426114.THI_3763 2e-15 75.9 COG1922@1|root,COG1922@2|Bacteria,1N1HD@1224|Proteobacteria,2VPIW@28216|Betaproteobacteria,1KJDM@119065|unclassified Burkholderiales 28216|Betaproteobacteria M Belongs to the glycosyltransferase 26 family tagA - 2.4.1.187 ko:K05946,ko:K13660 ko05111,map05111 - - - ko00000,ko00001,ko01000,ko01003 - GT26 - Glyco_tran_WecB,STAS_2 k59_43542_1 655097.C8ZKG1_9CAUD 1.89e-48 167.0 4QEG2@10239|Viruses,4QVSD@35237|dsDNA viruses no RNA stage,4QRJ9@28883|Caudovirales,4QP0R@10744|Podoviridae 10744|Podoviridae S exonuclease activity - - - - - - - - - - - - - k59_200825_2 1273125.Rrhod_2045 0.000585 46.6 COG5479@1|root,COG5479@2|Bacteria,2GNDB@201174|Actinobacteria,4FUE3@85025|Nocardiaceae 201174|Actinobacteria M Animal peptidoglycan recognition proteins homologous to Bacteriophage T3 lysozyme. csp - - - - - - - - - - - Amidase_2,LGFP k59_101378_1 105154.Q9MBU6_9VIRU 1.49e-139 415.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_35040_3 1279038.KB907337_gene131 5.51e-23 94.7 2E645@1|root,330T3@2|Bacteria,1NEGX@1224|Proteobacteria,2UJTA@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Holin of 3TMs, for gene-transfer release - - - - - - - - - - - - GTA_holin_3TM k59_27056_1 1234888.K0A2J2_9VIRU 5.37e-54 186.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_101379_3 186617.M9MJB7_9VIRU 8.06e-05 45.8 4QB1C@10239|Viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_200829_1 768066.HELO_4194 2.74e-110 335.0 COG3378@1|root,COG3378@2|Bacteria,1QVIS@1224|Proteobacteria,1S02S@1236|Gammaproteobacteria,1XP9I@135619|Oceanospirillales 135619|Oceanospirillales S Phage plasmid primase P4 family - - - ko:K06919 - - - - ko00000 - - - - k59_259219_1 1475143.W8SNN0_9CIRC 5.03e-37 144.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_159100_2 1316739.R4JMY7_9CAUD 3.14e-147 444.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_59713_4 1316936.K678_00215 1.18e-43 165.0 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,2TVGJ@28211|Alphaproteobacteria,2JPR0@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - k59_167899_1 1054968.G0X535_9CAUD 8.91e-28 122.0 4QB4B@10239|Viruses,4QWC6@35237|dsDNA viruses no RNA stage,4QQNI@28883|Caudovirales,4QNPA@10744|Podoviridae 10744|Podoviridae S Glutamine amidotransferase domain - - - - - - - - - - - - - k59_167899_2 1141137.K4F6X6_9CAUD 9.84e-16 84.7 4QFSQ@10239|Viruses,4R063@35237|dsDNA viruses no RNA stage,4QT6M@28883|Caudovirales,4QP2G@10744|Podoviridae 10744|Podoviridae S ligase activity - - - - - - - - - - - - - k59_118374_1 1354303.M917_0430 6.04e-108 328.0 COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,1RNVR@1236|Gammaproteobacteria,3NKJE@468|Moraxellaceae 1236|Gammaproteobacteria P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family kefB - - ko:K03455,ko:K11745,ko:K11747 - - - - ko00000,ko02000 2.A.37,2.A.37.1.1,2.A.37.1.2 - - Na_H_Exchanger,TrkA_N k59_226048_4 2003327.CAPSD_BPCHP 1.9e-58 199.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_35139_2 1100721.ALKO01000016_gene1463 8.06e-11 68.2 COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,2VIA1@28216|Betaproteobacteria,4AC5G@80864|Comamonadaceae 28216|Betaproteobacteria KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance spoT - 2.7.6.5,3.1.7.2 ko:K01139 ko00230,map00230 - R00336,R00429 RC00002,RC00078 ko00000,ko00001,ko01000,ko03009 - - - ACT_4,HD_4,RelA_SpoT,TGS k59_2317_1 438753.AZC_3583 7.15e-30 125.0 28IA2@1|root,2Z8CQ@2|Bacteria,1PQM2@1224|Proteobacteria,2TUAP@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_135614_3 1123279.ATUS01000001_gene2720 9.56e-82 261.0 COG4128@1|root,COG4128@2|Bacteria,1RCY8@1224|Proteobacteria,1S4JQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Zonular occludens toxin (Zot) - - - ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko02042 - - - Zot k59_135614_10 675806.VII_002331 7.55e-53 187.0 2CI0W@1|root,2Z81W@2|Bacteria,1R9FZ@1224|Proteobacteria,1S0NA@1236|Gammaproteobacteria,1XW6F@135623|Vibrionales 135623|Vibrionales S Phage replication protein CRI - - - - - - - - - - - - Phage_CRI,Phage_X k59_201764_1 1120963.KB894508_gene3902 3.94e-76 244.0 COG0270@1|root,COG0270@2|Bacteria,1MV9D@1224|Proteobacteria,1RPD1@1236|Gammaproteobacteria,2Q3YP@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria L C-5 cytosine-specific DNA methylase dcm - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_226730_1 635013.TherJR_1286 2.1e-08 60.1 COG1388@1|root,COG1388@2|Bacteria,1UHY7@1239|Firmicutes,24FFK@186801|Clostridia,263QN@186807|Peptococcaceae 186801|Clostridia M Peptidoglycan-binding LysM - - - - - - - - - - - - Cu_amine_oxidN1,LysM,SH3_3 k59_234383_1 1788438.A0A190WHE1_9CIRC 1.22e-11 72.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_52786_2 1509403.GW12_08350 4.36e-46 169.0 2CDPS@1|root,2ZBQT@2|Bacteria,1RB59@1224|Proteobacteria,1S2U0@1236|Gammaproteobacteria,3NKKP@468|Moraxellaceae 1236|Gammaproteobacteria S Phage X family g2p - - - - - - - - - - - Phage_CRI,Phage_X k59_160059_2 471874.PROSTU_01885 6.81e-26 112.0 COG4643@1|root,COG4643@2|Bacteria,1MW9E@1224|Proteobacteria,1RXXG@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Zinc-binding domain of primase-helicase - - - - - - - - - - - - Prim_Zn_Ribbon,Toprim_3 k59_168904_1 1329516.JPST01000005_gene1303 6.48e-13 77.0 COG0863@1|root,COG0863@2|Bacteria,1UWKM@1239|Firmicutes,4IC4N@91061|Bacilli,27D8U@186824|Thermoactinomycetaceae 91061|Bacilli L DNA methylase - - - - - - - - - - - - N6_N4_Mtase k59_260229_1 1244869.H261_10537 2.28e-65 213.0 COG0175@1|root,COG0175@2|Bacteria,1PZ96@1224|Proteobacteria 1224|Proteobacteria EH 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase and related enzymes - - - - - - - - - - - - PAPS_reduct k59_201907_1 10753.B7SSM8_BPNF 5.96e-41 156.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QNI0@10744|Podoviridae 10744|Podoviridae S viral capsid - GO:0005575,GO:0019012,GO:0019028,GO:0019030,GO:0039617,GO:0044423,GO:0046729 - - - - - - - - - - - k59_194015_2 1618248.A0A0C5IB82_9CIRC 1.28e-13 73.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_61291_4 186617.M9M8L2_9VIRU 2.79e-101 314.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_103192_2 1611039.A0A0C5C3Z3_9CIRC 3.39e-12 71.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_19874_6 1385658.U5KPZ6_9VIRU 2.3e-219 624.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_19874_7 679935.Alfi_0537 1.37e-11 65.5 2DQ6T@1|root,33509@2|Bacteria,4NUY9@976|Bacteroidetes,2FTIZ@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_19874_9 105154.Q9MBU3_9VIRU 2.33e-10 62.4 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_136885_2 1788444.A0A190WHA5_9CIRC 2.44e-41 151.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_145662_3 1499967.BAYZ01000003_gene5885 6.64e-10 61.6 COG4627@1|root,COG4627@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - BON,Glycos_transf_2,Methyltransf_11 k59_153558_1 1304275.C41B8_05313 2.33e-09 67.8 COG0454@1|root,COG1040@1|root,COG0456@2|Bacteria,COG1040@2|Bacteria,1R2FE@1224|Proteobacteria,1T5PV@1236|Gammaproteobacteria 1236|Gammaproteobacteria K acetyltransferase - - - - - - - - - - - - - k59_220672_3 1117108.PAALTS15_06714 0.000653 50.4 COG0438@1|root,COG0438@2|Bacteria,1UASH@1239|Firmicutes,4HKSK@91061|Bacilli,26QSQ@186822|Paenibacillaceae 91061|Bacilli M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k59_210623_2 1536592.A0A088FB34_9VIRU 3.81e-30 120.0 4QDKA@10239|Viruses 10239|Viruses S nuclease activity - - - - - - - - - - - - - k59_120437_4 1449126.JQKL01000006_gene840 8.51e-21 101.0 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,2487V@186801|Clostridia 186801|Clostridia L DNA polymerase - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_36811_1 438753.AZC_3589 2.32e-52 184.0 COG0209@1|root,COG0209@2|Bacteria,1N0E3@1224|Proteobacteria,2UQM4@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Ribonucleotide reductase, barrel domain - - 1.1.98.6 ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000 - - - Ribonuc_red_lgC k59_228012_2 457424.BFAG_01420 3.82e-30 120.0 COG0438@1|root,COG0438@2|Bacteria,4PMG0@976|Bacteroidetes,2G0BT@200643|Bacteroidia,4AV5A@815|Bacteroidaceae 976|Bacteroidetes H Pfam:DUF1792 - - - - - - - - - - - - GT-D k59_228012_3 395495.Lcho_0484 3.76e-24 106.0 COG2227@1|root,COG2520@1|root,COG2227@2|Bacteria,COG2520@2|Bacteria 2|Bacteria J tRNA (guanine(37)-N(1))-methyltransferase activity - - - - - - - - - - - - Glycos_transf_2,Methyltransf_11,Methyltransf_21,Methyltransf_23,Methyltransf_25 k59_228012_4 357276.EL88_06620 5.7e-08 56.6 COG0438@1|root,COG0438@2|Bacteria,4PMG0@976|Bacteroidetes,2G0BT@200643|Bacteroidia,4AV5A@815|Bacteroidaceae 976|Bacteroidetes H Pfam:DUF1792 - - - - - - - - - - - - GT-D k59_29229_3 557598.LHK_01542 3.08e-136 397.0 28HXV@1|root,2Z83C@2|Bacteria,1PJBP@1224|Proteobacteria,2VZV5@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_29229_6 1121434.AULY01000011_gene1829 2.85e-30 130.0 28HPK@1|root,2Z7XJ@2|Bacteria,1NBHR@1224|Proteobacteria,42YKK@68525|delta/epsilon subdivisions,2WUDS@28221|Deltaproteobacteria,2M8E7@213115|Desulfovibrionales 28221|Deltaproteobacteria S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_252153_2 999413.HMPREF1094_04677 1.1e-06 49.7 2DRJA@1|root,33C0M@2|Bacteria,1VKIR@1239|Firmicutes 1239|Firmicutes S Domain of Unknown Function with PDB structure (DUF3850) - - - - - - - - - - - - DUF3850 k59_120439_2 1162295.I1TRA9_9CAUD 8.42e-19 88.6 4QCMK@10239|Viruses,4QUPQ@35237|dsDNA viruses no RNA stage,4QS1R@28883|Caudovirales,4QKCR@10662|Myoviridae 10662|Myoviridae S methyltransferase activity - - - - - - - - - - - - - k59_95775_1 1129794.C427_2431 6.34e-43 149.0 28M7D@1|root,2ZAKV@2|Bacteria,1R6BC@1224|Proteobacteria,1S7HU@1236|Gammaproteobacteria,46BHI@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_87147_1 649747.HMPREF0083_05323 2.37e-30 124.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4H9YP@91061|Bacilli,26W69@186822|Paenibacillaceae 91061|Bacilli L SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,SNF2_N k59_95777_2 105154.Q9MBU6_9VIRU 1.29e-90 283.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_236545_2 1234888.K0A2J2_9VIRU 4.87e-142 424.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_204532_2 652103.Rpdx1_2535 4.21e-08 63.9 2DQ9V@1|root,335IH@2|Bacteria 2|Bacteria - - - - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - - k59_87148_1 1157708.KB907450_gene5441 4.38e-08 64.3 COG5434@1|root,COG5434@2|Bacteria,1RCW1@1224|Proteobacteria,2W4G2@28216|Betaproteobacteria 28216|Betaproteobacteria M Pectate lyase superfamily protein - - - - - - - - - - - - Pectate_lyase_3 k59_113733_3 397945.Aave_1710 1.36e-27 109.0 2AFJZ@1|root,336NA@2|Bacteria,1N9T7@1224|Proteobacteria,2VZ0D@28216|Betaproteobacteria,4AIWD@80864|Comamonadaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_79786_1 1609634.A0A0C5AFV4_9VIRU 1.46e-38 145.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_130502_3 269796.Rru_A3313 8.8e-48 170.0 28IR7@1|root,2Z8QR@2|Bacteria,1PBTP@1224|Proteobacteria,2U248@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_55383_1 575564.HMPREF0014_00749 7.06e-25 108.0 COG0454@1|root,COG1196@1|root,COG0456@2|Bacteria,COG1196@2|Bacteria,1QWY8@1224|Proteobacteria,1T2ZJ@1236|Gammaproteobacteria,3NMSX@468|Moraxellaceae 1236|Gammaproteobacteria K nuclear chromosome segregation - - - - - - - - - - - - - k59_236642_2 999549.KI421514_gene424 1.48e-47 164.0 COG0582@1|root,COG0582@2|Bacteria,1NWGS@1224|Proteobacteria,2TQWR@28211|Alphaproteobacteria,28291@191028|Leisingera 28211|Alphaproteobacteria L Phage integrase family - - - - - - - - - - - - Phage_integrase k59_21038_1 102129.Lepto7375DRAFT_7273 2.03e-11 65.1 2EHVE@1|root,33BKZ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_6278_1 426716.JOAJ01000016_gene5310 0.000226 47.4 COG2909@1|root,COG2909@2|Bacteria,2GM1B@201174|Actinobacteria,4FZRD@85025|Nocardiaceae 201174|Actinobacteria K AAA ATPase domain - - - - - - - - - - - - AAA_16,GerE k59_195488_2 686340.Metal_2595 6.76e-48 162.0 2EKAP@1|root,33E0Y@2|Bacteria,1NAAI@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_55388_1 743719.PaelaDRAFT_2381 1.89e-17 86.7 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,4H9Z7@91061|Bacilli,26RQI@186822|Paenibacillaceae 91061|Bacilli L DNA polymerase - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_229384_1 1692257.A0A0K1RL39_9CIRC 1.47e-66 216.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_139778_1 1894.JOER01000003_gene2915 2.87e-11 75.9 COG3291@1|root,COG3291@2|Bacteria,2GKNE@201174|Actinobacteria 201174|Actinobacteria NU Collagenase - - - - - - - - - - - - PKD,Peptidase_M9,Peptidase_M9_N k59_115153_1 1385658.U5KPZ6_9VIRU 1.87e-205 588.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_115302_1 102129.Lepto7375DRAFT_7444 1.38e-48 166.0 COG0270@1|root,COG0270@2|Bacteria 2|Bacteria L DNA (cytosine-5-)-methyltransferase activity - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_63595_9 1121921.KB898706_gene3042 5.44e-55 188.0 28J9D@1|root,2Z94E@2|Bacteria,1QE0C@1224|Proteobacteria,1RZ22@1236|Gammaproteobacteria 1236|Gammaproteobacteria S P22 coat protein - gene protein 5 - - - - - - - - - - - - P22_CoatProtein k59_180774_1 1218084.BBJK01000077_gene5333 2.8e-31 130.0 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,2VP7E@28216|Betaproteobacteria,1KFK1@119060|Burkholderiaceae 28216|Betaproteobacteria S Phage portal protein - - - - - - - - - - - - Phage_portal k59_163788_1 1609634.A0A0C5AFV4_9VIRU 1.03e-27 111.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_263893_1 344021.Q3YJY4_BPK1F 6.17e-39 150.0 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales,4QNBW@10744|Podoviridae 10744|Podoviridae S DNA helicase activity - - - - - - - - - - - - - k59_189749_1 575589.HMPREF0018_00079 1.84e-17 86.3 2CDPS@1|root,2ZBQT@2|Bacteria,1RB59@1224|Proteobacteria,1S2U0@1236|Gammaproteobacteria,3NQPU@468|Moraxellaceae 1236|Gammaproteobacteria S Phage X family g2p - - - - - - - - - - - Phage_CRI,Phage_X k59_212980_1 11082.PRO_0000037746 1.05e-80 256.0 4QBXT@10239|Viruses,4R138@439488|ssRNA viruses,4R0R1@35278|ssRNA positive-strand viruses no DNA stage 10239|Viruses K ATP-dependent helicase activity - GO:0001510,GO:0001959,GO:0001960,GO:0002682,GO:0002683,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003725,GO:0003727,GO:0003824,GO:0004482,GO:0004483,GO:0005488,GO:0005575,GO:0006139,GO:0006370,GO:0006396,GO:0006397,GO:0006508,GO:0006725,GO:0006807,GO:0006810,GO:0006897,GO:0006898,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008171,GO:0008173,GO:0008174,GO:0008233,GO:0008757,GO:0009451,GO:0009452,GO:0009605,GO:0009607,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009966,GO:0009968,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010646,GO:0010648,GO:0010941,GO:0016032,GO:0016070,GO:0016071,GO:0016192,GO:0016556,GO:0016740,GO:0016741,GO:0016787,GO:0018995,GO:0019012,GO:0019031,GO:0019048,GO:0019049,GO:0019050,GO:0019054,GO:0019058,GO:0019065,GO:0019068,GO:0019219,GO:0019222,GO:0019538,GO:0020012,GO:0023051,GO:0023057,GO:0030260,GO:0030430,GO:0030682,GO:0030683,GO:0031323,GO:0031324,GO:0031329,GO:0031330,GO:0031347,GO:0031348,GO:0032259,GO:0032991,GO:0032993,GO:0033592,GO:0033643,GO:0033646,GO:0033655,GO:0033668,GO:0034641,GO:0035821,GO:0036260,GO:0036265,GO:0036338,GO:0039502,GO:0039503,GO:0039526,GO:0039713,GO:0039714,GO:0042981,GO:0043067,GO:0043069,GO:0043170,GO:0043207,GO:0043412,GO:0043414,GO:0043487,GO:0043489,GO:0043656,GO:0043657,GO:0043900,GO:0043902,GO:0043903,GO:0044003,GO:0044068,GO:0044215,GO:0044216,GO:0044217,GO:0044237,GO:0044238,GO:0044260,GO:0044403,GO:0044409,GO:0044413,GO:0044414,GO:0044415,GO:0044419,GO:0044423,GO:0044501,GO:0044531,GO:0044532,GO:0044766,GO:0045069,GO:0045070,GO:0045088,GO:0045824,GO:0045934,GO:0046483,GO:0046718,GO:0046755,GO:0046762,GO:0046794,GO:0048518,GO:0048519,GO:0048523,GO:0048524,GO:0048583,GO:0048585,GO:0050690,GO:0050776,GO:0050777,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051252,GO:0051253,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051806,GO:0051807,GO:0051817,GO:0051828,GO:0051832,GO:0051833,GO:0051834,GO:0052027,GO:0052029,GO:0052031,GO:0052037,GO:0052040,GO:0052041,GO:0052150,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052248,GO:0052250,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052433,GO:0052490,GO:0052493,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0060147,GO:0060149,GO:0060255,GO:0060338,GO:0060339,GO:0060548,GO:0060759,GO:0060761,GO:0060966,GO:0060967,GO:0060968,GO:0060969,GO:0065007,GO:0065008,GO:0071704,GO:0072583,GO:0075109,GO:0075111,GO:0075112,GO:0075114,GO:0075136,GO:0075509,GO:0075512,GO:0075528,GO:0080009,GO:0080090,GO:0080134,GO:0090304,GO:0097159,GO:0097617,GO:0098657,GO:0106005,GO:0140096,GO:0140098,GO:1900368,GO:1900369,GO:1901360,GO:1901363,GO:1901564,GO:1902369,GO:1902579,GO:1903900,GO:1903902,GO:1990814,GO:1990904 - - - - - - - - - - - k59_14306_4 105154.Q9MBU6_9VIRU 2.97e-18 83.6 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_148724_1 1094496.m07a_08960 3.77e-34 133.0 28MVD@1|root,2ZB2Y@2|Bacteria,1R8NK@1224|Proteobacteria,2U265@28211|Alphaproteobacteria,48TXM@772|Bartonellaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF4043) - - - - - - - - - - - - DUF4043 k59_148724_4 1502851.FG93_01932 8.88e-07 58.5 2DPZ1@1|root,3340X@2|Bacteria,1R2EE@1224|Proteobacteria,2TZIB@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_223708_2 1479235.KK366039_gene510 6.33e-09 57.4 COG1846@1|root,COG1846@2|Bacteria,1N9BM@1224|Proteobacteria 1224|Proteobacteria K Transcriptional regulator - - - - - - - - - - - - HTH_27,MarR_2 k59_23763_2 365659.smi_0179 1.13e-27 106.0 COG0317@1|root,COG0317@2|Bacteria,1VC5K@1239|Firmicutes,4IEB4@91061|Bacilli,2TPZP@28037|Streptococcus mitis 91061|Bacilli KT HD domain - - - - - - - - - - - - - k59_231696_1 913970.F8RW84_9VIRU 9.86e-17 81.6 4QCVK@10239|Viruses,4QUMV@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_157402_1 1122981.AUME01000026_gene550 8.95e-24 107.0 COG0553@1|root,COG0553@2|Bacteria,4NG6P@976|Bacteroidetes,2FPNU@200643|Bacteroidia 976|Bacteroidetes L SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,SNF2_N k59_106791_2 1219035.NT2_13_00580 8.73e-61 202.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_82148_1 1116369.KB890024_gene3021 1.38e-13 78.2 28HCK@1|root,2Z7PE@2|Bacteria,1NK7S@1224|Proteobacteria,2TSMJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_74290_1 866895.HBHAL_2430 3.94e-11 70.1 COG2931@1|root,COG2931@2|Bacteria,1TSGB@1239|Firmicutes,4HBZW@91061|Bacilli 91061|Bacilli Q Collagen triple helix repeat (20 copies) - - - - - - - - - - - - Collagen k59_57783_2 1618251.A0A0C5I2L8_9CIRC 3.79e-35 138.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_247273_2 1121271.AUCM01000031_gene2563 2.97e-52 176.0 COG3772@1|root,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,2UDUF@28211|Alphaproteobacteria 28211|Alphaproteobacteria G lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - PG_binding_1,Phage_lysozyme k59_64701_1 1192868.CAIU01000008_gene937 1.5e-78 249.0 COG0863@1|root,COG0863@2|Bacteria,1NQ2A@1224|Proteobacteria,2UJ12@28211|Alphaproteobacteria,43KMC@69277|Phyllobacteriaceae 28211|Alphaproteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - - - - - - - - - - - N6_N4_Mtase k59_64701_4 742767.HMPREF9456_03404 3.26e-51 171.0 COG0270@1|root,COG0270@2|Bacteria,4P351@976|Bacteroidetes 976|Bacteroidetes L DNA (cytosine-5-)-methyltransferase activity - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_264903_1 1788454.A0A190WHE4_9CIRC 6.72e-45 156.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_264903_2 1379718.S5TMX4_9CIRC 4.15e-15 77.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_231843_1 1380394.JADL01000008_gene3768 4.41e-41 155.0 COG3064@1|root,COG3064@2|Bacteria,1R6JV@1224|Proteobacteria,2U5NE@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Membrane - - - - - - - - - - - - - k59_15595_1 1056820.KB900641_gene704 0.000733 45.4 29W5V@1|root,30HQZ@2|Bacteria,1RFZX@1224|Proteobacteria,1S4QF@1236|Gammaproteobacteria,2PQ6M@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria - - - - - - - - - - - - - - DUF4184,YdjM k59_214380_1 1235790.C805_00500 1.02e-25 106.0 COG1044@1|root,COG1044@2|Bacteria,1TP7W@1239|Firmicutes,24HJW@186801|Clostridia 186801|Clostridia M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxD - 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Hexapep,Hexapep_2,LpxD k59_57964_1 313596.RB2501_01415 1.74e-140 412.0 COG1061@1|root,COG2093@1|root,COG1061@2|Bacteria,COG2093@2|Bacteria,4NECV@976|Bacteroidetes,1HXAD@117743|Flavobacteriia 976|Bacteroidetes L Domain of unknown function (DUF3427) - - - - - - - - - - - - Helicase_C,ResIII k59_198116_2 272626.lin1248 0.000456 45.8 COG4570@1|root,COG4570@2|Bacteria,1VF2H@1239|Firmicutes,4HJ0V@91061|Bacilli 91061|Bacilli L holliday junction resolvase rusA - - - - - - - - - - - RusA k59_74463_1 408672.NBCG_04500 3.47e-14 74.7 COG0208@1|root,COG0208@2|Bacteria 2|Bacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdB - 1.17.4.1 ko:K00526,ko:K03676 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03110,ko03400 - - - ATP-cone,Ribonuc_red_sm k59_74463_2 1075399.BLBCPU_291 8.42e-76 252.0 COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,1HXHB@117743|Flavobacteriia,3IVAK@39782|Blattabacteriaceae 976|Bacteroidetes F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdA - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_lgC,Ribonuc_red_lgN k59_82328_1 1096930.L284_16395 6.06e-19 90.5 COG1573@1|root,COG1573@2|Bacteria,1MW8T@1224|Proteobacteria,2TSAR@28211|Alphaproteobacteria,2K0Y7@204457|Sphingomonadales 204457|Sphingomonadales L Uracil-DNA glycosylase - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - DUF4130,UDG k59_91470_1 1609634.A0A0C5AFV4_9VIRU 1.04e-144 426.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_91470_4 1609634.A0A0C5AFT2_9VIRU 2.31e-107 325.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_33486_1 1552758.NC00_01260 1.47e-11 70.1 COG3566@1|root,COG3566@2|Bacteria,1REIQ@1224|Proteobacteria,1SZWW@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2213) - - - - - - - - - - - - DUF2213 k59_66627_2 641147.HMPREF9021_02663 8.9e-16 88.2 COG3941@1|root,COG3941@2|Bacteria,1RM44@1224|Proteobacteria,2VSWE@28216|Betaproteobacteria,2KPD6@206351|Neisseriales 206351|Neisseriales D nuclear chromosome segregation - - - - - - - - - - - - Tape_meas_lam_C k59_166113_5 580332.Slit_1922 1.12e-49 185.0 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1NKZK@1224|Proteobacteria,2VM59@28216|Betaproteobacteria 28216|Betaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_133052_1 1618248.A0A0C5IB82_9CIRC 1.28e-54 181.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_141289_5 1234888.K0A2J2_9VIRU 3.45e-160 470.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_108162_2 521000.PROVRETT_05530 1.28e-25 99.0 COG3179@1|root,COG3179@2|Bacteria,1RE8K@1224|Proteobacteria,1S4U8@1236|Gammaproteobacteria,3Z9BP@586|Providencia 1236|Gammaproteobacteria S D-alanyl-D-alanine carboxypeptidase - - - - - - - - - - - - Peptidase_M15_4 k59_141291_2 489825.LYNGBM3L_53260 1.93e-20 95.5 COG0438@1|root,COG0438@2|Bacteria,1FZUY@1117|Cyanobacteria,1H72J@1150|Oscillatoriales 1117|Cyanobacteria M glycosyl transferase - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_11,Glyco_transf_4,Glyco_transf_41,Glycos_transf_1,Glycos_transf_2,Methyltransf_21,Methyltransf_24 k59_66629_2 1120934.KB894459_gene1386 4.11e-18 85.9 2E1TZ@1|root,32X3N@2|Bacteria,2IH16@201174|Actinobacteria,4EBC0@85010|Pseudonocardiales 201174|Actinobacteria S AAA domain - - - - - - - - - - - - AAA_25 k59_224164_3 1692252.A0A0K1RL35_9CIRC 1.54e-69 221.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_224164_4 1618238.A0A0C5IB41_9CIRC 3.79e-09 60.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_174270_3 641149.HMPREF9016_01178 1.31e-05 48.5 2EI4V@1|root,33BW7@2|Bacteria,1R1BA@1224|Proteobacteria 1224|Proteobacteria S Protein of unknwon function (DUF3310) - - - - - - - - - - - - DUF3310 k59_257442_5 1506583.JQJY01000003_gene3390 5.77e-08 61.2 COG1196@1|root,COG1511@1|root,COG1196@2|Bacteria,COG1511@2|Bacteria 2|Bacteria Q domain protein yjeP - - ko:K01421,ko:K02004,ko:K02316,ko:K05802,ko:K10953,ko:K12684,ko:K22051 ko03030,ko05110,map03030,map05110 M00258 - - ko00000,ko00001,ko00002,ko01000,ko02000,ko02042,ko02044,ko03032 1.A.23.1.1,1.A.23.1.2,1.A.23.1.3,1.B.12.4,3.A.1 - - AAA_15,MS_channel,MscS_TM,MscS_porin k59_41809_2 1692244.A0A0K1RLR5_9CIRC 5.5e-66 214.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_67308_1 1477404.A0A023NFX4_9CAUD 1.11e-100 334.0 4QAXA@10239|Viruses,4QYJI@35237|dsDNA viruses no RNA stage,4QQ1A@28883|Caudovirales,4QNU7@10744|Podoviridae 10744|Podoviridae S metallopeptidase activity - - - - - - - - - - - - - k59_75663_1 1379707.S5T672_9CIRC 6.16e-12 71.2 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_142036_1 1692244.A0A0K1RLR5_9CIRC 1.3e-25 102.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_142036_3 1618248.A0A0C5IB82_9CIRC 4.57e-08 60.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_1149_1 1096546.WYO_0171 9.62e-63 213.0 COG0553@1|root,COG0553@2|Bacteria,1PXS8@1224|Proteobacteria,2UAZ5@28211|Alphaproteobacteria 28211|Alphaproteobacteria KL COG0553 Superfamily II DNA RNA helicases, SNF2 family - - - - - - - - - - - - SNF2_N k59_125486_3 742740.HMPREF9474_04296 1.15e-06 59.3 COG5280@1|root,COG5280@2|Bacteria,1UMXV@1239|Firmicutes 1239|Firmicutes S Phage tail tape measure protein TP901 - - - - - - - - - - - - - k59_133740_2 1618251.A0A0C5I2L8_9CIRC 3.1e-59 199.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_100445_1 1788439.A0A190WHD0_9CIRC 2.11e-58 196.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_174831_1 1331060.RLDS_24530 9.44e-22 97.4 COG0286@1|root,COG0286@2|Bacteria,1RFKR@1224|Proteobacteria,2UQNP@28211|Alphaproteobacteria,2K37Z@204457|Sphingomonadales 204457|Sphingomonadales V N-6 DNA Methylase - - - - - - - - - - - - N6_Mtase k59_174831_2 272942.RCAP_rcc00944 3.84e-25 103.0 COG1475@1|root,COG1475@2|Bacteria,1MVH7@1224|Proteobacteria,2TRNA@28211|Alphaproteobacteria,1FCEI@1060|Rhodobacter 28211|Alphaproteobacteria K ParB-like nuclease domain - - - - - - - - - - - - N6_N4_Mtase,ParBc k59_108751_1 1379713.S5SYD9_9CIRC 1.16e-27 107.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_108751_4 1379709.S5TMV0_9CIRC 7.66e-60 196.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_34388_2 1385512.N784_10825 4.54e-09 67.4 COG0210@1|root,COG0210@2|Bacteria,1TPVG@1239|Firmicutes,4HBVF@91061|Bacilli,2YBGW@289201|Pontibacillus 91061|Bacilli L Cold-inducible protein YdjO yjcD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C,YdjO k59_100613_2 5888.CAK94299 8.85e-13 74.7 2CN00@1|root,2QT19@2759|Eukaryota,3ZBGU@5878|Ciliophora 5878|Ciliophora S Tetratricopeptide repeat - - - - - - - - - - - - TPR_1,TPR_8 k59_9348_1 460265.Mnod_6991 3.45e-06 48.9 COG1475@1|root,COG1475@2|Bacteria,1MVH7@1224|Proteobacteria 1224|Proteobacteria KL Belongs to the N(4) N(6)-methyltransferase family - - - - - - - - - - - - ParBc k59_75836_1 1385658.U5KPZ6_9VIRU 9.02e-63 209.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_126487_2 1402135.SUH3_12065 7.43e-24 99.0 28VW5@1|root,2ZHXK@2|Bacteria,1P4GB@1224|Proteobacteria,2UWZ2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_51671_4 1165094.RINTHH_3920 7.46e-57 189.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_217921_5 1297570.MESS4_p20014 8.08e-11 58.5 2C3WM@1|root,3002C@2|Bacteria,1R3MS@1224|Proteobacteria,2U048@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Domain of unknown function (DUF4326) - - - - - - - - - - - - DUF4326 k59_184274_1 1121374.KB891586_gene2571 9.7e-16 82.8 COG0358@1|root,COG0358@2|Bacteria,1P00T@1224|Proteobacteria,1RNHB@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Toprim-like - - - - - - - - - - - - DUF927,Toprim_2 k59_118472_1 648757.Rvan_3315 2.86e-78 254.0 COG5323@1|root,COG5323@2|Bacteria,1MW8S@1224|Proteobacteria,2TREI@28211|Alphaproteobacteria,3N62D@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_3,Terminase_6,Terminase_6C k59_208997_3 438753.AZC_3597 1.82e-66 223.0 COG0749@1|root,COG0749@2|Bacteria,1P27P@1224|Proteobacteria,2TVEI@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DNA polymerase family A - - - - - - - - - - - - DNA_pol_A k59_151474_2 582402.Hbal_1563 1.7e-17 82.4 COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,2TRJX@28211|Alphaproteobacteria,43X2D@69657|Hyphomonadaceae 28211|Alphaproteobacteria M Belongs to the KdsA family kdsA - 2.5.1.55 ko:K01627 ko00540,ko01100,map00540,map01100 M00063 R03254 RC00435 ko00000,ko00001,ko00002,ko01000,ko01005 - - - DAHP_synth_1 k59_143275_1 1527515.A0A088FB05_9CAUD 2.55e-08 53.1 4QAVB@10239|Viruses,4QPIJ@28883|Caudovirales,4QM0Q@10699|Siphoviridae 10699|Siphoviridae S Phage lysozyme - GO:0001906,GO:0001907,GO:0003674,GO:0003796,GO:0003824,GO:0004553,GO:0008150,GO:0008933,GO:0016032,GO:0016740,GO:0016757,GO:0016787,GO:0016798,GO:0019048,GO:0019058,GO:0019076,GO:0031640,GO:0035821,GO:0035890,GO:0035891,GO:0039633,GO:0040011,GO:0044003,GO:0044004,GO:0044364,GO:0044403,GO:0044419,GO:0044659,GO:0044661,GO:0051701,GO:0051704,GO:0051817,GO:0051818,GO:0051883,GO:0052126,GO:0052192,GO:0061783 - - - - - - - - - - - k59_143275_2 1500386.A0A060AFL1_9CAUD 4.37e-12 68.2 4QAIU@10239|Viruses,4QPDE@28883|Caudovirales,4QKM7@10699|Siphoviridae 10699|Siphoviridae S HNH endonuclease - - - - - - - - - - - - - k59_168023_3 291603.REP7_FBNY1 4.34e-09 62.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_76705_6 1124982.MSI_25110 2.01e-05 50.1 COG0593@1|root,COG0593@2|Bacteria,2J5F6@203691|Spirochaetes 203691|Spirochaetes L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA - - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N k59_126673_1 136084.Q9G0H0_9CAUD 2.06e-26 117.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_151483_1 1986029.Q9MBM6_9VIRU 1.02e-14 72.4 4QDBB@10239|Viruses,4QUM0@29258|ssDNA viruses,4QP4D@10841|Microviridae 10841|Microviridae S Chlamydia-phage Chp2 scaffold (Chlamy_scaf) - - - - - - - - - - - - - k59_101477_2 948071.S4S2D9_9CAUD 1.27e-44 162.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QNQ6@10744|Podoviridae 10744|Podoviridae S ribonucleoside-triphosphate reductase activity - - - - - - - - - - - - - k59_111201_2 490913.C4NTE4_9CAUD 1.02e-68 224.0 4QBYE@10239|Viruses,4QVYH@35237|dsDNA viruses no RNA stage,4QQTP@28883|Caudovirales,4QP46@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_77888_1 1548905.A0A0A1IX16_9CAUD 1.5e-19 88.2 4QBTT@10239|Viruses,4QQUU@28883|Caudovirales,4QKWB@10699|Siphoviridae 10699|Siphoviridae S Phage conserved hypothetical protein BR0599 - - - - - - - - - - - - - k59_77888_2 1175654.A0A0S0N2N8_9CAUD 9e-21 84.7 4QGE9@10239|Viruses,4QVDG@35237|dsDNA viruses no RNA stage,4QS71@28883|Caudovirales,4QMTZ@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_77888_4 1548905.A0A0A1IVS6_9CAUD 6.19e-50 181.0 4QAQ9@10239|Viruses,4QPTV@28883|Caudovirales,4QKRS@10699|Siphoviridae 10699|Siphoviridae S Putative phage tail protein - GO:0005575,GO:0008150,GO:0016032,GO:0018995,GO:0019012,GO:0019058,GO:0019062,GO:0022610,GO:0030430,GO:0033643,GO:0033646,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044403,GO:0044406,GO:0044419,GO:0044650,GO:0051704 - - - - - - - - - - - k59_111202_2 329726.AM1_2857 1.17e-87 262.0 COG0717@1|root,COG0717@2|Bacteria,1G2R2@1117|Cyanobacteria 1117|Cyanobacteria F Belongs to the dCTP deaminase family dcd - 3.5.4.13 ko:K01494 ko00240,ko01100,map00240,map01100 M00053 R00568,R02325 RC00074 ko00000,ko00001,ko00002,ko01000 - - - dUTPase k59_152830_1 1242864.D187_006025 1.18e-11 73.6 COG1404@1|root,COG3291@1|root,COG3509@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG3509@2|Bacteria,1MU3S@1224|Proteobacteria,42N7D@68525|delta/epsilon subdivisions,2WKJS@28221|Deltaproteobacteria,2YZ9E@29|Myxococcales 28221|Deltaproteobacteria OQ Bacterial Ig-like domain (group 3) - - - - - - - - - - - - Big_3_2,Big_3_3,Inhibitor_I9,Peptidase_S8 k59_102601_1 942016.E9NID5_9CAUD 4.37e-35 133.0 4QBMV@10239|Viruses,4QUU6@35237|dsDNA viruses no RNA stage,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_102601_2 1121121.KB894304_gene3341 1.66e-39 136.0 2CA0E@1|root,349DP@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_177173_1 1002339.HMPREF9373_1500 3.1e-212 586.0 COG3039@1|root,COG3039@2|Bacteria,1Q9AW@1224|Proteobacteria,1RNU1@1236|Gammaproteobacteria,3NKHK@468|Moraxellaceae 1236|Gammaproteobacteria L Transposase DDE domain - - - - - - - - - - - - DDE_Tnp_1_3 k59_185453_1 1215092.PA6_009_00310 2.32e-19 91.3 28TC4@1|root,2ZFKJ@2|Bacteria,1P81C@1224|Proteobacteria,1SUYI@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_185453_2 1096546.WYO_0193 1.56e-122 362.0 28JC4@1|root,2Z96S@2|Bacteria,1RI8W@1224|Proteobacteria 1224|Proteobacteria S P22 coat protein-protein 5 domain protein - - - - - - - - - - - - - k59_160431_1 438753.AZC_3598 5.58e-144 428.0 COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1QT52@1224|Proteobacteria,2TVNI@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Toprim-like - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - DnaB_C,Toprim_2 k59_152837_1 1416009.V9VHQ3_9CAUD 2.84e-28 116.0 4QEQT@10239|Viruses,4QYJH@35237|dsDNA viruses no RNA stage,4QQ1B@28883|Caudovirales,4QNPW@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_193297_5 2003327.CAPSD_BPCHP 6.75e-67 233.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_28468_1 1234888.K0A2J2_9VIRU 5.66e-90 282.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_111203_1 220341.16506051 2.07e-52 189.0 COG1783@1|root,COG1783@2|Bacteria,1MWGP@1224|Proteobacteria,1S8D6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C k59_260480_1 1234888.K0A2J2_9VIRU 2.38e-110 336.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_53174_1 1408418.JNJH01000012_gene3580 1.88e-31 122.0 28N1N@1|root,2ZB7Q@2|Bacteria,1R86T@1224|Proteobacteria,2U0A6@28211|Alphaproteobacteria,2JRMI@204441|Rhodospirillales 204441|Rhodospirillales H Sulfotransferase domain - - - - - - - - - - - - Sulfotransfer_1 k59_210054_1 675813.VIB_000051 7.07e-08 62.8 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1XUAZ@135623|Vibrionales 135623|Vibrionales L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_210054_2 575540.Isop_2448 8.8e-24 95.9 COG3613@1|root,COG3613@2|Bacteria 2|Bacteria F nucleoside 2-deoxyribosyltransferase - - - - - - - - - - - - DUF1937 k59_234797_1 66692.ABC1341 7.49e-11 68.2 COG1196@1|root,COG3953@1|root,COG4942@1|root,COG5283@1|root,COG1196@2|Bacteria,COG3953@2|Bacteria,COG4942@2|Bacteria,COG5283@2|Bacteria,1UHQM@1239|Firmicutes,4HGW7@91061|Bacilli,1ZBWW@1386|Bacillus 91061|Bacilli D phage tail tape measure protein - - - - - - - - - - - - Peptidase_M23,PhageMin_Tail,SLT k59_78004_1 1415774.U728_1674 2.11e-09 62.4 COG1783@1|root,COG1783@2|Bacteria,1TRQP@1239|Firmicutes,248E9@186801|Clostridia,36EE3@31979|Clostridiaceae 186801|Clostridia L Phage terminase, large subunit, PBSX family - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C k59_78004_2 472759.Nhal_1137 1.7e-29 110.0 COG1403@1|root,COG1403@2|Bacteria,1N6FJ@1224|Proteobacteria 1224|Proteobacteria V HNH endonuclease - - - - - - - - - - - - - k59_211056_1 1234888.K0A2J2_9VIRU 3.24e-79 255.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_29772_1 1127515.H9C0H6_9CAUD 1.68e-33 138.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QI9F@10662|Myoviridae 10662|Myoviridae S Type III restriction enzyme, res subunit - - - - - - - - - - - - - k59_161715_1 1692244.A0A0K1RLR5_9CIRC 3.64e-62 202.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_194586_1 1234888.K0A2J2_9VIRU 2.74e-45 166.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_95125_1 1385658.U5KPZ6_9VIRU 1.24e-171 502.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_5371_1 7220.FBpp0141925 5.31e-06 52.4 2CMNT@1|root,2QR3D@2759|Eukaryota,39UHX@33154|Opisthokonta,3B9U3@33208|Metazoa,3D2YM@33213|Bilateria,4201I@6656|Arthropoda,3SN7B@50557|Insecta,4553X@7147|Diptera,45X9Q@7214|Drosophilidae 33208|Metazoa G N-acetylmuramoyl-L-alanine amidase activity. It is involved in the biological process described with peptidoglycan catabolic process - GO:0000270,GO:0002376,GO:0002682,GO:0002683,GO:0003674,GO:0003824,GO:0005488,GO:0005539,GO:0005575,GO:0005576,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0006950,GO:0006952,GO:0006955,GO:0008150,GO:0008152,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0016787,GO:0016810,GO:0016811,GO:0030203,GO:0031347,GO:0031348,GO:0042834,GO:0043170,GO:0045087,GO:0045088,GO:0045824,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0061783,GO:0065007,GO:0071704,GO:0080134,GO:0097367,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - ko:K01446 - - R04112 RC00064,RC00141 ko00000 - - - Amidase_2 k59_129685_3 1692248.A0A0K1RLN2_9CIRC 3.95e-80 251.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_178767_1 520999.PROVALCAL_01902 1.24e-08 57.0 2EJ6P@1|root,33CXW@2|Bacteria,1NPIH@1224|Proteobacteria,1SIRF@1236|Gammaproteobacteria,3ZAE2@586|Providencia 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_20522_1 1609634.A0A0C5AFV4_9VIRU 8.8e-25 110.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_86608_1 1125863.JAFN01000001_gene2457 1.55e-09 56.2 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,42TV9@68525|delta/epsilon subdivisions,2WNAN@28221|Deltaproteobacteria 28221|Deltaproteobacteria L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_179831_1 348824.LPU83_1739 2.88e-16 87.4 COG0553@1|root,COG0553@2|Bacteria,1MX6H@1224|Proteobacteria,2TUMR@28211|Alphaproteobacteria,4BG55@82115|Rhizobiaceae 28211|Alphaproteobacteria KL SNF2 family N-terminal domain - - 2.1.1.72 ko:K07316 - - - - ko00000,ko01000,ko02048 - - - Helicase_C,SNF2_N k59_179995_2 1500301.JQMF01000006_gene1773 5.76e-141 442.0 COG5108@1|root,COG5108@2|Bacteria,1PIWB@1224|Proteobacteria,2U1JR@28211|Alphaproteobacteria,4BC0X@82115|Rhizobiaceae 28211|Alphaproteobacteria K DNA-directed RNA polymerase N-terminal - - - - - - - - - - - - RNA_pol,RPOL_N k59_31404_1 312309.VF_2017 2.84e-34 121.0 2CPEB@1|root,32SIW@2|Bacteria,1MZE0@1224|Proteobacteria,1SARU@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_47987_1 709797.CSIRO_2382 1.23e-24 102.0 2CK39@1|root,32SBG@2|Bacteria,1MZ6F@1224|Proteobacteria,2UBT5@28211|Alphaproteobacteria,3JYTE@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Phage gp6-like head-tail connector protein - - - - - - - - - - - - Phage_connect_1 k59_72357_1 1622190.A0A0E3T5U7_9CAUD 5.92e-10 61.6 4QKP3@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_72357_2 1622190.A0A0E3T7W2_9CAUD 1.94e-51 187.0 4QAKZ@10239|Viruses,4QPYH@28883|Caudovirales,4QM57@10699|Siphoviridae 10699|Siphoviridae S intein-mediated protein splicing - - - - - - - - - - - - - k59_122632_1 1692247.A0A0K1RL30_9CIRC 2.54e-26 112.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_263087_1 1609634.A0A0C5AFV4_9VIRU 3.5e-07 51.6 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_263087_3 1609634.A0A0C5AFT2_9VIRU 1.62e-75 241.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_229819_1 198110.B3FK10_9CAUD 1.33e-07 55.8 4QBHW@10239|Viruses,4QVHG@35237|dsDNA viruses no RNA stage,4QTT7@28883|Caudovirales,4QJZQ@10662|Myoviridae 10662|Myoviridae S sequence-specific DNA binding transcription factor activity - - - - - - - - - - - - - k59_13531_1 948071.S4S2D9_9CAUD 1.42e-134 402.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QNQ6@10744|Podoviridae 10744|Podoviridae S ribonucleoside-triphosphate reductase activity - - - - - - - - - - - - - k59_130951_1 1234888.K0A2J2_9VIRU 6.76e-55 192.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_180010_1 1121468.AUBR01000104_gene3117 1.93e-97 304.0 COG0863@1|root,COG0863@2|Bacteria,1TR56@1239|Firmicutes,248NR@186801|Clostridia 186801|Clostridia L Belongs to the N(4) N(6)-methyltransferase family cfr9IM - 2.1.1.113 ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_139100_1 1120956.JHZK01000029_gene96 3.58e-09 59.3 COG1403@1|root,COG1403@2|Bacteria,1MWEQ@1224|Proteobacteria,2TR3M@28211|Alphaproteobacteria,1JNQA@119043|Rhodobiaceae 28211|Alphaproteobacteria L HNH nucleases MA20_20605 - - - - - - - - - - - HNH,HNH_5 k59_114465_2 691965.D4P7D6_9CAUD 1.9e-15 78.6 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_13546_1 1116482.K9L5J1_9CAUD 1.37e-16 80.5 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales 28883|Caudovirales S HNH endonuclease - - - - - - - - - - - - - k59_229832_2 743719.PaelaDRAFT_5930 2.02e-08 59.7 COG1573@1|root,COG1573@2|Bacteria,1V4M9@1239|Firmicutes,4HHJN@91061|Bacilli,26XQI@186822|Paenibacillaceae 91061|Bacilli L UreE urease accessory protein, C-terminal domain ung2 - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k59_147999_1 760011.Spico_0804 2.79e-21 99.4 COG4733@1|root,COG4733@2|Bacteria 2|Bacteria S cellulase activity - - 3.2.1.8 ko:K01181 - - - - ko00000,ko01000 - - - Big_2,CBM9_1,CBM_4_9,Cellulase,DUF285,Glyco_hydro_10,SLH,VCBS,fn3 k59_73545_1 351627.Csac_0105 6.31e-24 101.0 COG0602@1|root,COG0602@2|Bacteria,1TQ58@1239|Firmicutes,2499R@186801|Clostridia,42H70@68295|Thermoanaerobacterales 186801|Clostridia H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds queE - 4.3.99.3 ko:K10026 ko00790,ko01100,map00790,map01100 - R10002 RC02989 ko00000,ko00001,ko01000,ko03016 - - - Fer4_12,Fer4_14,Radical_SAM k59_181143_1 105154.Q9MBU3_9VIRU 1.6e-11 63.5 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_181143_2 2003327.CAPSD_BPCHP 1.92e-38 142.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_156677_2 1618248.A0A0C5IB82_9CIRC 3.12e-83 259.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_8241_1 1234888.K0A2J2_9VIRU 5.78e-69 227.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_238063_3 1609634.A0A0C5AFV4_9VIRU 2.37e-13 70.5 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_196966_1 1692259.A0A0K1RL59_9CIRC 9.43e-10 61.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_164216_1 1676184.A0A186YBN5_9CIRC 5.26e-45 158.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_115667_8 1246459.KB898357_gene1632 1.94e-52 187.0 COG5301@1|root,COG5301@2|Bacteria,1N6XX@1224|Proteobacteria,2USJX@28211|Alphaproteobacteria 28211|Alphaproteobacteria G cellulose 1,4-beta-cellobiosidase activity - - - - - - - - - - - - - k59_39647_1 107635.AZUO01000001_gene908 3.88e-08 60.5 28JTG@1|root,2Z9IR@2|Bacteria,1R0GC@1224|Proteobacteria,2TURR@28211|Alphaproteobacteria,36XR3@31993|Methylocystaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF2793) - - - - - - - - - - - - DUF2793 k59_106311_1 1522072.IL54_3078 2.65e-31 119.0 2DQEE@1|root,336AX@2|Bacteria,1MY8N@1224|Proteobacteria,2UI1U@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Exonuclease (EC 3.1.11.3) (P03697 of bacteriophage lambda) exo - 3.1.11.3 ko:K01143 - - - - ko00000,ko01000 - - - YqaJ k59_115762_1 105420.BBPO01000018_gene5358 1.03e-20 90.1 2EB9A@1|root,3359T@2|Bacteria,2INFV@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_22937_2 406817.XNC1_3075 5.35e-20 85.5 2DNV9@1|root,32ZB3@2|Bacteria,1MZGP@1224|Proteobacteria,1SE04@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - VP1566 - - - - - - - - - - - - k59_197133_4 457412.RSAG_01145 3.59e-75 250.0 COG4383@1|root,COG4383@2|Bacteria,1TS7T@1239|Firmicutes,24CCB@186801|Clostridia,3WNCM@541000|Ruminococcaceae 186801|Clostridia S Mu-like prophage protein gp29 - - - - - - - - - - - - - k59_197133_9 562742.F4YXT5_9CAUD 1.12e-13 72.0 4QB9S@10239|Viruses,4QUXK@35237|dsDNA viruses no RNA stage,4QPW1@28883|Caudovirales,4QM6J@10699|Siphoviridae 10699|Siphoviridae S Phage major capsid protein E - GO:0005575,GO:0019012,GO:0019028,GO:0019030,GO:0039620,GO:0044423 - - - - - - - - - - - k59_173738_2 1234888.K0A2R8_9VIRU 1.23e-63 209.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_173738_5 1234888.K0A2J2_9VIRU 3.4e-115 350.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_255041_1 526222.Desal_1441 4.15e-41 155.0 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,42Z58@68525|delta/epsilon subdivisions,2WTW4@28221|Deltaproteobacteria,2M8HG@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_182345_1 1234888.K0A2J2_9VIRU 1.43e-44 161.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_40843_2 755731.Clo1100_1163 4.14e-08 58.2 COG0740@1|root,COG0740@2|Bacteria,1TR2H@1239|Firmicutes,249NC@186801|Clostridia,36DUJ@31979|Clostridiaceae 186801|Clostridia OU Belongs to the peptidase S14 family - - 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease k59_264969_2 1379717.S5SY19_9CIRC 1.19e-28 119.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_98677_2 1540097.A0A0A0YRL3_9CAUD 1.6e-10 61.6 4QD9V@10239|Viruses,4QTHS@28883|Caudovirales,4QP1H@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_107250_5 1454202.PPBDW_90555___1 5.9e-05 44.7 arCOG06669@1|root,2ZC1E@2|Bacteria,1RBUZ@1224|Proteobacteria,1S2MV@1236|Gammaproteobacteria,1Y11D@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k59_265002_2 650150.ERH_1292 9.36e-18 90.1 28MKK@1|root,2ZAWR@2|Bacteria,1UYAT@1239|Firmicutes,3VSD5@526524|Erysipelotrichia 526524|Erysipelotrichia S Putative viral replication protein - - - - - - - - - - - - RNA_helicase,Viral_Rep k59_107251_1 1123355.JHYO01000035_gene591 7.61e-45 154.0 28HS3@1|root,2Z7ZE@2|Bacteria,1QH9A@1224|Proteobacteria,2TVB0@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_165743_1 1692244.A0A0K1RLR5_9CIRC 4.87e-35 129.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_107256_2 1520935.A0A0H3UB63_9CIRC 8.97e-28 115.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_98691_1 1529058.A0A076GBC9_9CAUD 2.12e-10 62.4 4QGAG@10239|Viruses,4QUA4@28883|Caudovirales,4QNFP@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_98691_2 1161935.H9D1H5_9CAUD 5.68e-160 477.0 4QCM5@10239|Viruses,4QVZY@35237|dsDNA viruses no RNA stage,4QQFH@28883|Caudovirales,4QNDH@10744|Podoviridae 10744|Podoviridae S Bacteriophage head to tail connecting protein - GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019028,GO:0019058,GO:0019068,GO:0019072,GO:0019073,GO:0032991,GO:0044403,GO:0044419,GO:0044423,GO:0046798,GO:0051704 - - - - - - - - - - - k59_98691_4 1197951.I6S6J9_9CAUD 2.01e-08 60.5 4QE6E@10239|Viruses,4QV23@35237|dsDNA viruses no RNA stage,4QTFG@28883|Caudovirales 28883|Caudovirales S protein dimerization activity - - - - - - - - - - - - - k59_247901_1 593750.Metfor_2662 7.34e-08 56.2 COG0717@1|root,arCOG04048@2157|Archaea,2Y071@28890|Euryarchaeota,2N9T7@224756|Methanomicrobia 224756|Methanomicrobia F TIGRFAM deoxycytidine triphosphate deaminase - - 3.5.4.13 ko:K01494 ko00240,ko01100,map00240,map01100 M00053 R00568,R02325 RC00074 ko00000,ko00001,ko00002,ko01000 - - - dUTPase k59_98695_1 105154.Q9MBU6_9VIRU 3.81e-45 167.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_165756_1 1033743.CAES01000078_gene3733 1.13e-06 53.5 2E5K5@1|root,330BC@2|Bacteria,1VC9N@1239|Firmicutes,4HM43@91061|Bacilli 91061|Bacilli S Siphovirus Gp157 - - - - - - - - - - - - Sipho_Gp157 k59_265004_3 1986029.Q9MBM7_9VIRU 4.6e-13 72.0 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_265004_4 105154.Q9MBU6_9VIRU 2.68e-198 571.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_265004_6 1165094.RINTHH_3920 7.33e-75 239.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_89372_1 118166.JH976537_gene3680 2.27e-09 59.7 COG0305@1|root,COG1372@1|root,COG0305@2|Bacteria,COG1372@2|Bacteria,1G0R8@1117|Cyanobacteria,1H75W@1150|Oscillatoriales 1117|Cyanobacteria L Participates in initiation and elongation during chromosome replication dnaB GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3 k59_374_4 438753.AZC_3598 3.99e-15 75.9 COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1QT52@1224|Proteobacteria,2TVNI@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Toprim-like - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - DnaB_C,Toprim_2 k59_249192_1 1692252.A0A0K1RL35_9CIRC 1.73e-82 256.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_33584_1 1121921.KB898707_gene993 1.38e-64 229.0 COG0454@1|root,COG1040@1|root,COG0456@2|Bacteria,COG1040@2|Bacteria,1QV41@1224|Proteobacteria,1RSAP@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis - - - - - - - - - - - - - k59_215995_5 644801.Psest_2191 6.56e-75 248.0 2CDPS@1|root,2ZBQT@2|Bacteria,1RB59@1224|Proteobacteria,1S2U0@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage replication protein CRI g2p - - - - - - - - - - - Phage_CRI,Phage_X k59_215995_6 1123519.PSJM300_14835 2.09e-44 165.0 COG0464@1|root,COG0464@2|Bacteria,1QU82@1224|Proteobacteria,1SA9J@1236|Gammaproteobacteria,1Z2EZ@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria O Zonular occludens toxin (Zot) - - - - - - - - - - - - Zot k59_141332_1 1205681.CALW02000097_gene1626 7.15e-21 94.7 COG4675@1|root,COG4675@2|Bacteria,1N0FZ@1224|Proteobacteria,2VFMC@28211|Alphaproteobacteria,48UPF@772|Bartonellaceae 28211|Alphaproteobacteria S Phage Tail Collar Domain - - - - - - - - - - - - Collar k59_257477_3 105154.Q9MBU6_9VIRU 2.82e-195 564.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_232594_1 1217708.F887_01942 2.74e-34 132.0 2BZ9Z@1|root,2Z97E@2|Bacteria,1RD7Q@1224|Proteobacteria,1S06R@1236|Gammaproteobacteria,3NMUV@468|Moraxellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_166157_1 1410631.JHWZ01000009_gene73 5.22e-15 74.3 COG0270@1|root,COG0270@2|Bacteria,1TS3G@1239|Firmicutes,249Q9@186801|Clostridia,27KBU@186928|unclassified Lachnospiraceae 186801|Clostridia H C-5 cytosine-specific DNA methylase dcm - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_174312_1 1230338.MOMA_06926 5.14e-30 120.0 COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,1RY1X@1236|Gammaproteobacteria 1236|Gammaproteobacteria S associated with various cellular activities - - - - - - - - - - - - AAA,AAA_5 k59_174312_2 1476391.X5KNA6_9CAUD 2.49e-30 116.0 4QEMD@10239|Viruses,4R0JN@35237|dsDNA viruses no RNA stage,4QUGF@28883|Caudovirales,4QNXF@10744|Podoviridae 10744|Podoviridae S AAA domain - - - - - - - - - - - - - k59_58432_1 1234888.K0A2R8_9VIRU 2e-40 147.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_83311_3 1563661.A0A097PBD1_9CAUD 1.59e-81 253.0 4QFP7@10239|Viruses,4QSRU@28883|Caudovirales,4QNWE@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - - - - - - - - - - - - - k59_33585_4 1788439.A0A190WHD0_9CIRC 1.5e-31 123.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_108232_1 742740.HMPREF9474_02273 2.97e-11 66.2 2EAAT@1|root,334F2@2|Bacteria,1VJJI@1239|Firmicutes,24TQU@186801|Clostridia,223KD@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_108232_2 691965.D4P7C5_9CAUD 0.0 911.0 4QBV3@10239|Viruses,4QW0W@35237|dsDNA viruses no RNA stage,4QPPJ@28883|Caudovirales,4QKW5@10699|Siphoviridae 10699|Siphoviridae S Phage Terminase - - - - - - - - - - - - - k59_108232_3 428125.CLOLEP_01411 1.58e-159 463.0 28J3N@1|root,2Z8ZU@2|Bacteria,1V15Z@1239|Firmicutes,249Z0@186801|Clostridia,3WNJZ@541000|Ruminococcaceae 186801|Clostridia S Phage portal protein - - - - - - - - - - - - Phage_portal k59_108232_4 691965.D4P7D6_9CAUD 2.08e-201 590.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_108232_5 428125.CLOLEP_01413 3.9e-28 105.0 2E2Y0@1|root,32XYV@2|Bacteria,1VD9S@1239|Firmicutes,24PK0@186801|Clostridia,3WPDR@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_108232_7 742733.HMPREF9469_05026 1.19e-78 242.0 28NM4@1|root,2ZBMQ@2|Bacteria,1V1QD@1239|Firmicutes,24G1B@186801|Clostridia,221N8@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_108232_8 742733.HMPREF9469_05023 5.93e-39 138.0 2CGG9@1|root,2ZVSJ@2|Bacteria,1V633@1239|Firmicutes,24HD0@186801|Clostridia,222RY@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_83339_3 744980.TRICHSKD4_4529 6.65e-15 82.4 COG4675@1|root,COG4675@2|Bacteria,1N0FZ@1224|Proteobacteria,2UDXB@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Phage Tail Collar Domain - - - - - - - - - - - - Collar k59_33610_1 207559.Dde_3372 1.94e-24 109.0 COG4373@1|root,COG4373@2|Bacteria,1N2KG@1224|Proteobacteria,42NZD@68525|delta/epsilon subdivisions,2WJWU@28221|Deltaproteobacteria,2M8CI@213115|Desulfovibrionales 28221|Deltaproteobacteria S Mu-like prophage FluMu protein gp28 - - - - - - - - - - - - Terminase_6 k59_199854_1 1123504.JQKD01000002_gene3911 4.59e-47 165.0 COG4128@1|root,COG4128@2|Bacteria,1REHG@1224|Proteobacteria,2VRK2@28216|Betaproteobacteria,4AEKU@80864|Comamonadaceae 28216|Betaproteobacteria S Zonular occludens toxin (Zot) - - - - - - - - - - - - Zot k59_224819_2 1609634.A0A0C5ANA6_9VIRU 4.43e-17 79.0 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_233102_1 1403313.AXBR01000002_gene4334 6.26e-21 89.4 2BMR7@1|root,32GAM@2|Bacteria,1W5Q4@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - k59_67339_1 1458697.W6EKG4_9CAUD 1.6e-11 70.5 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QM2K@10699|Siphoviridae 10699|Siphoviridae S Phage Tail Collar Domain - - - - - - - - - - - - - k59_67339_2 1410624.JNKK01000045_gene546 8.24e-07 56.6 COG1511@1|root,COG4675@1|root,COG1511@2|Bacteria,COG4675@2|Bacteria,1V943@1239|Firmicutes,24PFY@186801|Clostridia 186801|Clostridia S PFAM Tail Collar domain protein - - - - - - - - - - - - Collar k59_199929_1 1096546.WYO_0164 4.81e-73 245.0 COG0749@1|root,COG0749@2|Bacteria,1MWX7@1224|Proteobacteria 1224|Proteobacteria L COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A,DNA_pol_A_exo1 k59_133771_1 1385658.U5KPZ6_9VIRU 6.73e-81 259.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_9271_1 1429767.W6AR13_9CAUD 7.53e-26 108.0 4QEFX@10239|Viruses,4QYYG@35237|dsDNA viruses no RNA stage,4QRRV@28883|Caudovirales,4QNTK@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_17332_3 1986029.Q9MBM3_9VIRU 1.91e-62 207.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_17332_5 1609634.A0A0C5AFV4_9VIRU 3.16e-18 84.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_50785_1 1477404.A0A023NH97_9CAUD 6.76e-140 420.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QNBK@10744|Podoviridae 10744|Podoviridae S Ribonucleotide reductase, barrel domain - - - - - - - - - - - - - k59_26630_1 1385658.U5KPZ6_9VIRU 8.38e-187 540.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_59477_5 398525.KB900701_gene5067 1.36e-17 76.6 2BZTS@1|root,33131@2|Bacteria,1NBBP@1224|Proteobacteria,2UIZA@28211|Alphaproteobacteria,3K1K3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_142752_1 1218352.B597_019385 5.86e-58 197.0 28IAN@1|root,2Z8D8@2|Bacteria,1NJD6@1224|Proteobacteria,1RY86@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4055) - - - - - - - - - - - - DUF4055 k59_51397_1 1120953.AUBH01000005_gene2212 1.03e-25 111.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,465DD@72275|Alteromonadaceae 1236|Gammaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_183857_1 10870.G1P_BPM13 7.19e-79 246.0 4QBME@10239|Viruses,4QUKP@29258|ssDNA viruses,4QP4G@10860|Inoviridae 10860|Inoviridae S Zonular occludens toxin (Zot) - - - - - - - - - - - - - k59_175419_1 691965.D4P7D6_9CAUD 3.18e-68 227.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_250216_6 1249997.JHZW01000003_gene3734 7.09e-17 90.9 COG1511@1|root,COG3210@1|root,COG1511@2|Bacteria,COG3210@2|Bacteria,4PKI0@976|Bacteroidetes,1IKUE@117743|Flavobacteriia,2PI31@252356|Maribacter 976|Bacteroidetes U PFAM Collagen triple helix repeat (20 copies) - - - - - - - - - - - - - k59_67926_1 1041524.F8R4Q2_9CAUD 9.51e-43 161.0 4QBMV@10239|Viruses,4QUU6@35237|dsDNA viruses no RNA stage,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_26686_1 1055815.AYYA01000003_gene1949 1.56e-182 513.0 COG5527@1|root,COG5527@2|Bacteria,1RD9C@1224|Proteobacteria,1T07W@1236|Gammaproteobacteria,3NTFJ@468|Moraxellaceae 1224|Proteobacteria L Initiator Replication protein - - - - - - - - - - - - Rep_3 k59_26686_2 1055815.AYYA01000027_gene573 1.21e-92 271.0 COG0789@1|root,COG0789@2|Bacteria,1NMFG@1224|Proteobacteria,1SZ25@1236|Gammaproteobacteria,3NNN9@468|Moraxellaceae 1236|Gammaproteobacteria K helix_turn_helix, mercury resistance - - - - - - - - - - - - - k59_26686_5 1002339.HMPREF9373_2624 1.49e-165 488.0 COG0507@1|root,COG0507@2|Bacteria,1MUTR@1224|Proteobacteria,1RQS3@1236|Gammaproteobacteria,3NJSK@468|Moraxellaceae 1236|Gammaproteobacteria L MobA/MobL family - - - - - - - - - - - - MobA_MobL k59_167537_3 1121926.AXWO01000001_gene3487 2.04e-21 91.7 COG0756@1|root,COG0756@2|Bacteria,2IHYY@201174|Actinobacteria,4EYNV@85014|Glycomycetales 201174|Actinobacteria F dUTPase dut GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase k59_167537_6 1160718.SU9_22210 2.12e-11 70.9 COG1573@1|root,COG1573@2|Bacteria,2GMPT@201174|Actinobacteria 201174|Actinobacteria L Uracil-DNA glycosylase dpo - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k59_18375_1 1121451.DESAM_22746 1.07e-43 161.0 COG5362@1|root,COG5362@2|Bacteria,1PYY9@1224|Proteobacteria,435M3@68525|delta/epsilon subdivisions,2WZZT@28221|Deltaproteobacteria,2M981@213115|Desulfovibrionales 28221|Deltaproteobacteria S TIGRFAM Phage - - - - - - - - - - - - - k59_110081_1 1385658.U5KNR1_9VIRU 1.01e-40 147.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_93295_1 1588764.A0A0E3GD36_9VIRU 1.99e-147 419.0 4QB6C@10239|Viruses 10239|Viruses L Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_93295_3 1588764.A0A0E3IQD7_9VIRU 3.84e-196 545.0 4QHM9@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_93295_4 1588764.A0A0E3GD36_9VIRU 1.73e-85 258.0 4QB6C@10239|Viruses 10239|Viruses L Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_218368_1 105154.Q9MBU6_9VIRU 1.09e-92 300.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_18377_1 1385658.U5KNR1_9VIRU 5.67e-37 135.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_151802_1 186617.M9M8L2_9VIRU 6.28e-116 349.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_259583_2 366394.Smed_1886 1.36e-09 59.7 2EDWZ@1|root,337S0@2|Bacteria,1N87K@1224|Proteobacteria,2UGNE@28211|Alphaproteobacteria,4BFIW@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_18423_1 1165094.RINTHH_3920 1.43e-53 179.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_35395_9 31033.ENSTRUP00000010399 5.74e-09 58.5 2BF6Y@1|root,2S16D@2759|Eukaryota,3A216@33154|Opisthokonta,3BQXI@33208|Metazoa,3D8B1@33213|Bilateria,48BMF@7711|Chordata,49B3K@7742|Vertebrata,4A478@7898|Actinopterygii 33208|Metazoa S Leukocyte cell-derived LECT2 GO:0001501,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0006935,GO:0007275,GO:0008150,GO:0009605,GO:0009966,GO:0009968,GO:0010646,GO:0010648,GO:0023051,GO:0023057,GO:0030111,GO:0030178,GO:0032501,GO:0032502,GO:0040011,GO:0042221,GO:0042330,GO:0042802,GO:0044421,GO:0044424,GO:0044464,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0048731,GO:0048856,GO:0050789,GO:0050794,GO:0050896,GO:0065007 - - - - - - - - - - Peptidase_M23 k59_2678_1 1165094.RINTHH_3920 1.15e-25 107.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_10296_1 1437882.AZRU01000006_gene1499 1.94e-30 119.0 COG0582@1|root,COG0582@2|Bacteria,1NWGS@1224|Proteobacteria,1S1RT@1236|Gammaproteobacteria,1YG3N@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria L Phage integrase family - - - - - - - - - - - - Phage_integrase k59_2681_1 1500301.JQMF01000006_gene1773 1.33e-30 124.0 COG5108@1|root,COG5108@2|Bacteria,1PIWB@1224|Proteobacteria,2U1JR@28211|Alphaproteobacteria,4BC0X@82115|Rhizobiaceae 28211|Alphaproteobacteria K DNA-directed RNA polymerase N-terminal - - - - - - - - - - - - RNA_pol,RPOL_N k59_218463_2 1274402.JQAJ01000001_gene25 1.54e-12 73.9 COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,2TT4Q@28211|Alphaproteobacteria,47F56@766|Rickettsiales 766|Rickettsiales L Uracil-DNA glycosylase - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k59_77069_1 1618237.A0A0C5IMG6_9CIRC 6.62e-10 63.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_27468_1 145579.CAPSD_BPPHM 4.92e-58 206.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_135228_1 1118055.CAGU01000060_gene694 2.45e-30 122.0 COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,22GQG@1570339|Peptoniphilaceae 186801|Clostridia L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_68535_2 1379725.S5TMY9_9CIRC 3.2e-16 80.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_234436_2 196367.JNFG01000004_gene5549 1.74e-06 51.6 2901T@1|root,2ZMS0@2|Bacteria,1P4IZ@1224|Proteobacteria,2W5ET@28216|Betaproteobacteria,1K7PU@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_176850_1 1265845.PWEIH_00500 2.23e-18 85.1 28MC2@1|root,2ZAQD@2|Bacteria,1VSEU@1239|Firmicutes,4HT1S@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k59_69171_1 1692257.A0A0K1RL39_9CIRC 4.31e-28 112.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_69171_2 1692242.A0A0K1RKZ2_9CIRC 1.16e-32 128.0 4QFEW@10239|Viruses,4QUKZ@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_69171_3 1618248.A0A0C5IB82_9CIRC 9.63e-52 174.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_226876_1 1379725.S5SYG4_9CIRC 2.58e-31 122.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_160187_2 318586.Pden_3738 1.38e-13 73.6 2CHRY@1|root,30Z9E@2|Bacteria,1RGQK@1224|Proteobacteria,2U9J0@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - RecT k59_44417_4 1401067.HMPREF0872_01230 6.95e-22 109.0 COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,4H24B@909932|Negativicutes 909932|Negativicutes L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity recD2 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 k59_44417_12 1123355.JHYO01000007_gene455 1.94e-47 161.0 COG1432@1|root,COG1432@2|Bacteria,1MUAE@1224|Proteobacteria,2TU5M@28211|Alphaproteobacteria,36XZ2@31993|Methylocystaceae 28211|Alphaproteobacteria S NYN domain MA20_36560 - - - - - - - - - - - NYN k59_209676_1 1385658.U5KPZ6_9VIRU 1.18e-108 333.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_193073_4 399795.CtesDRAFT_PD2911 2.46e-09 67.4 COG2304@1|root,COG3209@1|root,COG4733@1|root,COG2304@2|Bacteria,COG3209@2|Bacteria,COG4733@2|Bacteria,1MXB4@1224|Proteobacteria,2VJS7@28216|Betaproteobacteria,4AHBA@80864|Comamonadaceae 28216|Betaproteobacteria M Putative phage tail protein - - - - - - - - - - - - Phage-tail_3 k59_111431_1 693444.D782_2521 1.11e-15 77.8 COG3723@1|root,COG3723@2|Bacteria,1R6DB@1224|Proteobacteria,1RZZ3@1236|Gammaproteobacteria 1236|Gammaproteobacteria L COG3723 Recombinational DNA repair protein (RecE pathway) recT GO:0000724,GO:0000725,GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0018130,GO:0019438,GO:0032392,GO:0032508,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043150,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071704,GO:0071840,GO:0071897,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - ko:K07455 - - - - ko00000,ko03400 - - - RecT k59_85452_2 1197951.I6R9K8_9CAUD 7.74e-116 343.0 4QFIC@10239|Viruses,4QXG2@35237|dsDNA viruses no RNA stage,4QTVA@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_85452_9 213236.Q716M6_9CAUD 7.02e-06 55.8 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_153015_1 1234888.K0A2J2_9VIRU 3.32e-80 256.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_69608_1 1445613.JALM01000032_gene5141 1.62e-06 51.2 COG0438@1|root,COG0438@2|Bacteria,2HH27@201174|Actinobacteria,4E478@85010|Pseudonocardiales 201174|Actinobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 k59_243472_1 768704.Desmer_3271 8.01e-06 56.2 COG5301@1|root,COG5301@2|Bacteria,1UZU2@1239|Firmicutes,24EJ3@186801|Clostridia 186801|Clostridia S Protein of unknown function (DUF2793) - - - - - - - - - - - - DUF2793 k59_28658_1 1005994.GTGU_01426 2.74e-24 100.0 28JRN@1|root,2Z9H7@2|Bacteria,1R9A9@1224|Proteobacteria,1RNRW@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_11221_1 438753.AZC_3589 1.66e-71 236.0 COG0209@1|root,COG0209@2|Bacteria,1N0E3@1224|Proteobacteria,2UQM4@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Ribonucleotide reductase, barrel domain - - 1.1.98.6 ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000 - - - Ribonuc_red_lgC k59_136180_1 472175.EL18_02075 3.19e-08 54.3 2BZ9Z@1|root,2Z97E@2|Bacteria,1RD7Q@1224|Proteobacteria,2U775@28211|Alphaproteobacteria,43KX5@69277|Phyllobacteriaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_251556_1 342610.Patl_0706 1.72e-09 56.2 2BY2W@1|root,33316@2|Bacteria,1NA4T@1224|Proteobacteria,1SE5U@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_251556_2 488538.SAR116_2268 6.02e-31 115.0 2AD08@1|root,312N7@2|Bacteria,1Q8SH@1224|Proteobacteria,2UY5D@28211|Alphaproteobacteria,4BT40@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S Holin of 3TMs, for gene-transfer release - - - - - - - - - - - - GTA_holin_3TM k59_251556_3 1334046.AYTB01000013_gene436 9.86e-12 68.6 COG0582@1|root,COG0582@2|Bacteria,1V2RX@1239|Firmicutes,4HJ45@91061|Bacilli,26IDK@186818|Planococcaceae 91061|Bacilli L Phage integrase family - - - - - - - - - - - - Phage_integrase k59_3886_1 1280706.AUJE01000068_gene2912 0.000543 42.4 COG1396@1|root,COG1396@2|Bacteria 2|Bacteria K sequence-specific DNA binding - - - - - - - - - - - - HTH_3 k59_260673_1 1548905.A0A0A1IX16_9CAUD 1.85e-49 167.0 4QBTT@10239|Viruses,4QQUU@28883|Caudovirales,4QKWB@10699|Siphoviridae 10699|Siphoviridae S Phage conserved hypothetical protein BR0599 - - - - - - - - - - - - - k59_102751_1 1123269.NX02_04070 2.02e-17 78.2 2ED07@1|root,336X6@2|Bacteria,1N6RV@1224|Proteobacteria,2UHR8@28211|Alphaproteobacteria,2K6QR@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - k59_102751_2 1122963.AUHB01000024_gene131 1.32e-09 60.5 28HXV@1|root,2Z83C@2|Bacteria,1PJBP@1224|Proteobacteria,2U8DN@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_94167_1 28152.DJ57_2550 2.2e-42 158.0 28JKJ@1|root,2Z9DD@2|Bacteria,1MUN2@1224|Proteobacteria,1RQIP@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage P22-like portal protein - - - - - - - - - - - - P22_portal k59_144926_1 45351.EDO26034 2.34e-26 114.0 COG0749@1|root,2RV2U@2759|Eukaryota,3ATJG@33154|Opisthokonta 33154|Opisthokonta L DNA-directed DNA polymerase activity - - - - - - - - - - - - - k59_185674_1 755731.Clo1100_1145 3.13e-51 172.0 COG0863@1|root,COG0863@2|Bacteria,1V0ZF@1239|Firmicutes,24CQV@186801|Clostridia,36J76@31979|Clostridiaceae 186801|Clostridia L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_185676_1 665956.HMPREF1032_00687 1.41e-47 164.0 2E2JP@1|root,32XP4@2|Bacteria,1VAIM@1239|Firmicutes,24PPR@186801|Clostridia,3WI4W@541000|Ruminococcaceae 186801|Clostridia S Phage tail protein - - - - - - - - - - - - Sipho_tail k59_251567_1 883.DvMF_1065 1.41e-10 67.0 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,42Z58@68525|delta/epsilon subdivisions,2WTW4@28221|Deltaproteobacteria,2M8HG@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_111444_1 1150626.PHAMO_210084 9.57e-23 99.8 28N1N@1|root,2ZB7Q@2|Bacteria,1R86T@1224|Proteobacteria,2U0A6@28211|Alphaproteobacteria,2JRMI@204441|Rhodospirillales 204441|Rhodospirillales H Sulfotransferase domain - - - - - - - - - - - - Sulfotransfer_1 k59_219867_2 196490.AUEZ01000004_gene4030 1.79e-150 433.0 COG1032@1|root,COG1032@2|Bacteria,1NG4M@1224|Proteobacteria,2UKY8@28211|Alphaproteobacteria 28211|Alphaproteobacteria C radical SAM domain protein - - - - - - - - - - - - - k59_36315_1 44689.DDB0191106 1.22e-28 121.0 COG5108@1|root,KOG1038@2759|Eukaryota,3XANZ@554915|Amoebozoa 554915|Amoebozoa K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates - - 2.7.7.6 ko:K10908 - - - - ko00000,ko01000,ko03029 - - - RNA_pol,RPOL_N k59_227509_1 195253.Syn6312_1161 7.64e-28 110.0 COG2369@1|root,COG2369@2|Bacteria,1G8BV@1117|Cyanobacteria 1117|Cyanobacteria T domain, Protein - - - - - - - - - - - - - k59_45455_1 2003327.CAPSD_BPCHP 8.82e-34 135.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_45455_6 1234888.K0A2J2_9VIRU 7.23e-54 189.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_29057_1 259536.Psyc_1295 8.62e-92 275.0 COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,1RMXQ@1236|Gammaproteobacteria,3NIWJ@468|Moraxellaceae 1236|Gammaproteobacteria H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate lipB GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019222,GO:0019538,GO:0019752,GO:0032787,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048519,GO:0050789,GO:0051186,GO:0051188,GO:0051604,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.181 ko:K03801 ko00785,ko01100,map00785,map01100 - R07766,R07769 RC00039,RC00992,RC02867 ko00000,ko00001,ko01000 - - iECSF_1327.ECSF_0569,iSFV_1184.SFV_0696,iSFxv_1172.SFxv_0718 BPL_LplA_LipB k59_243897_2 1121921.KB898707_gene975 2.47e-82 261.0 COG5565@1|root,COG5565@2|Bacteria,1R6R3@1224|Proteobacteria,1RY0J@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C k59_243897_3 1121441.AUCX01000014_gene514 1.04e-70 231.0 COG5565@1|root,COG5565@2|Bacteria,1R6R3@1224|Proteobacteria,43BCR@68525|delta/epsilon subdivisions,2X6RN@28221|Deltaproteobacteria,2MA58@213115|Desulfovibrionales 28221|Deltaproteobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C k59_36616_1 1027273.GZ77_06260 4.05e-50 160.0 COG4737@1|root,COG4737@2|Bacteria,1N7N5@1224|Proteobacteria,1S6BG@1236|Gammaproteobacteria,1XMEE@135619|Oceanospirillales 135619|Oceanospirillales S Cytotoxic translational repressor of toxin-antitoxin stability system - - - - - - - - - - - - RelE k59_36616_2 983545.Glaag_1670 1.1e-45 149.0 COG2944@1|root,COG2944@2|Bacteria,1N0M9@1224|Proteobacteria,1T0CA@1236|Gammaproteobacteria,46D0N@72275|Alteromonadaceae 1236|Gammaproteobacteria K Antitoxin component of bacterial toxin-antitoxin system, MqsA - - - ko:K07726 - - - - ko00000,ko03000 - - - MqsA_antitoxin k59_251966_2 1385658.U5KNR1_9VIRU 5.65e-40 148.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_45460_1 794903.OPIT5_29915 7.43e-38 137.0 2E0FE@1|root,32W1M@2|Bacteria,46TEN@74201|Verrucomicrobia 74201|Verrucomicrobia - - - - - - - - - - - - - - DUF932 k59_235247_4 1122599.AUGR01000001_gene296 5.06e-80 254.0 COG0464@1|root,COG0464@2|Bacteria,1QU82@1224|Proteobacteria,1SA9J@1236|Gammaproteobacteria,1XPV6@135619|Oceanospirillales 135619|Oceanospirillales O Zonular occludens toxin (Zot) - - - - - - - - - - - - Zot k59_136767_1 105154.Q9MBU3_9VIRU 3.64e-10 60.1 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_136767_2 1385658.U5KPZ6_9VIRU 3.67e-110 334.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_227913_3 272134.KB731324_gene2733 1.07e-73 236.0 COG4834@1|root,COG4834@2|Bacteria 2|Bacteria S Uncharacterized protein conserved in bacteria (DUF2184) VY92_02880 - - - - - - - - - - - DUF2184 k59_145936_1 1233488.S4T7F5_9CAUD 7.99e-64 208.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QNNC@10744|Podoviridae 10744|Podoviridae S N-methyltransferase activity - - - - - - - - - - - - - k59_12101_2 1618258.A0A0C5I9K3_9CIRC 3.49e-29 118.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_37019_1 329726.AM1_2899 8.98e-14 75.1 2C6N9@1|root,32RHI@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - PDDEXK_1 k59_129316_1 1506572.A0A097ZPG0_9CIRC 1.01e-20 94.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_4964_1 169683.Q8SCY4_BPDPK 3.58e-49 180.0 4QG8W@10239|Viruses,4R0PA@35237|dsDNA viruses no RNA stage,4QSBS@28883|Caudovirales,4QJWA@10662|Myoviridae 10662|Myoviridae S DNA-directed RNA polymerase activity - - - - - - - - - - - - - k59_235582_1 1538804.A0A088F6T3_9CAUD 3.14e-95 304.0 4QAKM@10239|Viruses,4QPEF@28883|Caudovirales,4QKNE@10699|Siphoviridae 10699|Siphoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_120647_1 1142394.PSMK_02910 8.5e-40 137.0 COG0717@1|root,COG0717@2|Bacteria,2IZ2N@203682|Planctomycetes 203682|Planctomycetes F dUTPase - - 3.5.4.13 ko:K01494 ko00240,ko01100,map00240,map01100 M00053 R00568,R02325 RC00074 ko00000,ko00001,ko00002,ko01000 - - - dUTPase k59_12236_1 929562.Emtol_1027 7.56e-07 59.3 COG1044@1|root,COG5295@1|root,COG1044@2|Bacteria,COG5295@2|Bacteria,4NKG1@976|Bacteroidetes,47NK6@768503|Cytophagia 976|Bacteroidetes MUW domain, Protein - - - - - - - - - - - - Peptidase_S74 k59_228358_1 1183438.GKIL_0892 7.8e-38 145.0 COG5511@1|root,COG5511@2|Bacteria,1GDUF@1117|Cyanobacteria 1117|Cyanobacteria S Phage portal protein, lambda family - - - - - - - - - - - - Phage_portal_2 k59_129479_2 1234888.K0A2J2_9VIRU 8.12e-133 399.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_70626_1 948071.S4S2N2_9CAUD 3.67e-11 64.7 4QH10@10239|Viruses,4QVVN@35237|dsDNA viruses no RNA stage,4QSY9@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_70626_2 948071.S4S2T1_9CAUD 4.9e-58 204.0 4QHPY@10239|Viruses,4QWIA@35237|dsDNA viruses no RNA stage,4QSXS@28883|Caudovirales,4QNJ2@10744|Podoviridae 10744|Podoviridae S host cell wall - - - - - - - - - - - - - k59_78942_3 105154.Q9MBU6_9VIRU 1.69e-24 102.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_170641_2 644076.SCH4B_4381 3.02e-38 140.0 COG3935@1|root,COG3935@2|Bacteria,1MXB6@1224|Proteobacteria,2U3BK@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DnaD domain protein - - - - - - - - - - - - - k59_46122_3 10752.A0MZC7_BPN4 1.04e-44 168.0 4QBY0@10239|Viruses,4QW35@35237|dsDNA viruses no RNA stage,4QQ4Q@28883|Caudovirales,4QNNN@10744|Podoviridae 10744|Podoviridae S UvrD-like helicase C-terminal domain - - - - - - - - - - - - - k59_261611_1 1429916.X566_20010 8.1e-39 134.0 COG1917@1|root,COG1917@2|Bacteria,1N6Q0@1224|Proteobacteria,2UKI2@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Cupin 2, conserved barrel domain protein - - - - - - - - - - - - - k59_5055_1 1563661.A0A097PAN1_9CAUD 1.03e-123 382.0 4QF3C@10239|Viruses,4QU4U@28883|Caudovirales,4QNNQ@10744|Podoviridae 10744|Podoviridae S host cell wall - - - - - - - - - - - - - k59_5310_1 49964.Q94MR7_9CAUD 5.4e-71 238.0 4QERB@10239|Viruses,4R014@35237|dsDNA viruses no RNA stage,4QTGJ@28883|Caudovirales,4QNZG@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_244497_3 691965.D4P7L3_9CAUD 3.84e-82 262.0 4QBH7@10239|Viruses,4QWWF@35237|dsDNA viruses no RNA stage,4QQ8R@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_5424_1 1609634.A0A0C5AFV4_9VIRU 2.86e-51 179.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_211262_1 1279015.KB908456_gene1597 2.9e-11 67.0 COG5301@1|root,COG5301@2|Bacteria,1N4KH@1224|Proteobacteria,1RXZU@1236|Gammaproteobacteria,1Y5J9@135624|Aeromonadales 135624|Aeromonadales S Phage tail-collar fibre protein - - - - - - - - - - - - DUF3751 k59_121180_3 1380355.JNIJ01000009_gene1635 1.23e-50 183.0 COG1389@1|root,COG1389@2|Bacteria 2|Bacteria L DNA topoisomerase II activity top6B - 5.99.1.3 ko:K03167 - - - - ko00000,ko01000,ko03032 - - - HATPase_c,HATPase_c_3,Topo-VIb_trans k59_154365_1 1348114.OM33_08585 2.35e-36 132.0 COG0863@1|root,COG0863@2|Bacteria,1PCSQ@1224|Proteobacteria,1TKI6@1236|Gammaproteobacteria,2Q3TZ@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.72 ko:K00571,ko:K07319 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_228776_2 351746.Pput_4150 5.85e-76 243.0 COG0582@1|root,COG0582@2|Bacteria,1QB64@1224|Proteobacteria,1RY8S@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_1,Phage_int_SAM_4,Phage_integrase k59_46592_1 1096546.WYO_0201 6.3e-21 96.7 28P6A@1|root,2ZC10@2|Bacteria,1RBZE@1224|Proteobacteria,2UQEG@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_252822_1 55601.VANGNB10_cI1598c 1.25e-54 176.0 2DNA4@1|root,32WDI@2|Bacteria,1RH8K@1224|Proteobacteria,1S8YN@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage tail tube, TTP, lambda-like - - - - - - - - - - - - Phage_TTP_11 k59_252822_2 157783.LK03_13395 1.66e-37 130.0 2DM6W@1|root,32UGB@2|Bacteria,1N425@1224|Proteobacteria,1SGA9@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF3168) - - - - - - - - - - - - DUF3168 k59_12590_2 5811.TGME49_041870 3.43e-06 49.7 COG0008@1|root,KOG1149@2759|Eukaryota,3YBHJ@5794|Apicomplexa,3YMT7@5796|Coccidia,3YTH0@5809|Sarcocystidae 5794|Apicomplexa J tRNA ligase class I (E and Q), catalytic domain-containing protein - GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - - tRNA-synt_1c k59_86850_1 1379719.S5TMX6_9CIRC 3.07e-33 129.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_79395_2 234267.Acid_0151 1.13e-15 79.0 COG4675@1|root,COG4675@2|Bacteria,3Y4WB@57723|Acidobacteria 57723|Acidobacteria S Phage Tail Collar Domain - - - - - - - - - - - - Collar k59_121446_3 1429912.V5R9A1_9CAUD 1.33e-07 59.3 4QB4T@10239|Viruses,4QYFG@35237|dsDNA viruses no RNA stage,4QR7K@28883|Caudovirales,4QN2T@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_121446_4 1439940.BAY1663_02360 1.88e-21 100.0 28JTG@1|root,2Z9IR@2|Bacteria,1PCXZ@1224|Proteobacteria,1SIJB@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF2793) - - - - - - - - - - - - DUF2793 k59_104229_1 1609634.A0A0C5AFV4_9VIRU 1.75e-48 172.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_71301_4 1234874.K0A1L1_9VIRU 5.8e-39 140.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_211444_2 187944.H8YJ78_9CAUD 2.66e-06 49.7 4QD3N@10239|Viruses,4R04W@35237|dsDNA viruses no RNA stage,4QRN4@28883|Caudovirales,4QMPF@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_12823_2 570952.ATVH01000019_gene756 4.75e-21 94.4 COG1783@1|root,COG1783@2|Bacteria,1RAGC@1224|Proteobacteria,2U6JF@28211|Alphaproteobacteria,2JSIA@204441|Rhodospirillales 204441|Rhodospirillales S phage Terminase large subunit - - - - - - - - - - - - - k59_79396_1 911045.PSE_5032 5.82e-31 124.0 COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,2TQWC@28211|Alphaproteobacteria 28211|Alphaproteobacteria L COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member recD - 3.1.11.5 ko:K01144 - - - - ko00000,ko01000 - - - AAA_30,UvrD_C_2 k59_171239_3 1414739.W6AUX0_9CAUD 7.36e-05 54.3 4QBY0@10239|Viruses,4QW35@35237|dsDNA viruses no RNA stage 10239|Viruses S AAA domain - - - - - - - - - - - - - k59_5705_1 716544.wcw_0671 4.19e-80 253.0 COG4626@1|root,COG4626@2|Bacteria 2|Bacteria S Terminase - - - - - - - - - - - - Terminase_1 k59_79400_1 1158604.I591_00099 3.92e-05 49.7 COG3325@1|root,COG3979@1|root,COG3325@2|Bacteria,COG3979@2|Bacteria,1UPJ7@1239|Firmicutes,4HBA7@91061|Bacilli,4B0U2@81852|Enterococcaceae 91061|Bacilli G Glyco_18 chiB - 3.2.1.14 ko:K01183 ko00520,ko01100,map00520,map01100 - R01206,R02334 RC00467 ko00000,ko00001,ko01000 - GH18 - CBM_2,CBM_5_12,DUF5011,Glyco_hydro_18,fn3 k59_253071_1 1123508.JH636439_gene1604 2.01e-13 73.2 29XN2@1|root,30JDF@2|Bacteria,2J498@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - k59_236249_2 1379725.S5SYG4_9CIRC 3.64e-24 106.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_154620_1 322159.STER_B2 3.55e-47 167.0 COG5655@1|root,COG5655@2|Bacteria,1TTC4@1239|Firmicutes,4HEHZ@91061|Bacilli 91061|Bacilli L Replication protein - - - - - - - - - - - - Rep_1 k59_71685_4 1234888.K0A2J2_9VIRU 2.16e-92 296.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_138319_1 1234888.K0A2J2_9VIRU 5.26e-59 198.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_113760_1 1692246.A0A0K1RLM8_9CIRC 1.96e-26 107.0 4QBFZ@10239|Viruses,4QUKU@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_62456_2 96561.Dole_1281 4.77e-47 165.0 COG1089@1|root,COG1089@2|Bacteria,1MUX0@1224|Proteobacteria,42KZY@68525|delta/epsilon subdivisions,2WJ4B@28221|Deltaproteobacteria,2MJ21@213118|Desulfobacterales 28221|Deltaproteobacteria M Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose gmd - 4.2.1.47 ko:K01711 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R00888 RC00402 ko00000,ko00001,ko01000 - - - GDP_Man_Dehyd k59_104621_1 105154.Q9MBU6_9VIRU 1.32e-108 332.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_104621_2 105154.Q9MBU3_9VIRU 0.000492 46.6 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_245024_3 399795.CtesDRAFT_PD2911 4.68e-14 82.8 COG2304@1|root,COG3209@1|root,COG4733@1|root,COG2304@2|Bacteria,COG3209@2|Bacteria,COG4733@2|Bacteria,1MXB4@1224|Proteobacteria,2VJS7@28216|Betaproteobacteria,4AHBA@80864|Comamonadaceae 28216|Betaproteobacteria M Putative phage tail protein - - - - - - - - - - - - Phage-tail_3 k59_195404_1 571166.KI421509_gene1195 7.96e-07 52.8 28HHC@1|root,2Z7T2@2|Bacteria,1PZ57@1224|Proteobacteria,2U3R2@28211|Alphaproteobacteria 28211|Alphaproteobacteria S AAA domain - - - - - - - - - - - - AAA_24 k59_130452_1 688245.CtCNB1_1438 3.99e-48 165.0 28J67@1|root,2Z91Y@2|Bacteria,1R7RG@1224|Proteobacteria,2VRTM@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_187937_4 156889.Mmc1_1716 1.16e-141 410.0 28NGF@1|root,2ZBII@2|Bacteria,1R9KY@1224|Proteobacteria,2U1P7@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_253294_1 438753.AZC_3598 1.67e-102 320.0 COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1QT52@1224|Proteobacteria,2TVNI@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Toprim-like - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - DnaB_C,Toprim_2 k59_138337_1 1385658.U5KPZ6_9VIRU 2.57e-67 224.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_171657_1 1235835.C814_01159 1.16e-25 109.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,3WGFC@541000|Ruminococcaceae 186801|Clostridia KL SNF2 family - - - - - - - - - - - - Helicase_C,SNF2_N,SNF2_assoc,SWIM k59_20980_1 1609634.A0A0C5AFT2_9VIRU 1.79e-07 58.9 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_20980_2 105154.Q9MBU6_9VIRU 6.86e-94 304.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_87180_6 1122622.ATWJ01000008_gene2692 2.17e-05 44.7 2C4MW@1|root,32RKK@2|Bacteria,2IQ6A@201174|Actinobacteria,4FHDI@85021|Intrasporangiaceae 201174|Actinobacteria S Lsr2 lsr - - - - - - - - - - - Lsr2 k59_62508_2 1279019.ARQK01000045_gene517 1.73e-20 95.1 COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,1R97W@1224|Proteobacteria,1TK9M@1236|Gammaproteobacteria,1X0PG@135613|Chromatiales 135613|Chromatiales D Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_204665_2 316058.RPB_0919 1.21e-10 68.2 COG4675@1|root,COG4675@2|Bacteria,1NX1F@1224|Proteobacteria,2US1X@28211|Alphaproteobacteria,3K496@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Phage Tail Collar Domain - - - - - - - - - - - - Collar k59_204665_3 288000.BBta_6751 7.52e-11 64.7 COG4675@1|root,COG4675@2|Bacteria,1NX1F@1224|Proteobacteria,2US1X@28211|Alphaproteobacteria,3K496@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Phage Tail Collar Domain - - - - - - - - - - - - Collar k59_138429_1 1986029.Q9MBM8_9VIRU 2.49e-50 180.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_21014_1 1028800.RG540_CH08880 2.87e-05 44.7 2EJ3I@1|root,33CUS@2|Bacteria,1NGHC@1224|Proteobacteria,2UJVB@28211|Alphaproteobacteria,4BH02@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_253447_6 1385658.U5KPZ6_9VIRU 6.12e-178 513.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_87336_1 1522072.IL54_3177 2.29e-20 90.1 COG3566@1|root,COG3566@2|Bacteria,1N53Y@1224|Proteobacteria,2VG2D@28211|Alphaproteobacteria,2K9K0@204457|Sphingomonadales 204457|Sphingomonadales S Uncharacterized protein conserved in bacteria (DUF2213) - - - - - - - - - - - - DUF2213 k59_87336_2 1522072.IL54_3178 4.35e-20 87.8 COG2369@1|root,COG2369@2|Bacteria,1RFUM@1224|Proteobacteria,2UIAH@28211|Alphaproteobacteria,2KA1F@204457|Sphingomonadales 204457|Sphingomonadales S Phage Mu protein F like protein - - - - - - - - - - - - Phage_Mu_F k59_155254_3 796940.HMPREF9628_00135 2.03e-23 115.0 COG5283@1|root,COG5283@2|Bacteria,1UHQM@1239|Firmicutes,25E9Q@186801|Clostridia 186801|Clostridia M phage tail tape measure protein - - - - - - - - - - - - PhageMin_Tail k59_236725_1 1042209.HK44_020560 1.51e-107 321.0 2CYA9@1|root,32T3V@2|Bacteria,1RGRN@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_222460_1 438753.AZC_3588 2.44e-51 181.0 28MSK@1|root,2ZB0X@2|Bacteria,1R7CY@1224|Proteobacteria,2U2MY@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_55498_1 1609634.A0A0C5AFT2_9VIRU 2.73e-62 205.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_104840_1 1463854.JOHT01000033_gene2588 1.07e-09 63.9 COG0863@1|root,COG0863@2|Bacteria 2|Bacteria L N-4 methylation of cytosine - - 2.1.1.72 ko:K00571,ko:K07319 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_122195_2 1207076.ALAT01000105_gene1906 1.47e-23 94.7 2E3Y3@1|root,32YV3@2|Bacteria,1NC81@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - DUF2190 k59_147537_5 1167006.UWK_01394 3.46e-13 72.8 COG2204@1|root,COG2461@1|root,COG3275@1|root,COG4191@1|root,COG2204@2|Bacteria,COG2461@2|Bacteria,COG3275@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria,2MJ29@213118|Desulfobacterales 28221|Deltaproteobacteria T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - HATPase_c,HisKA,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,SBP_bac_3,dCache_3 k59_171887_2 1618241.A0A0C5I2I4_9CIRC 1.81e-51 172.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_229469_10 1341151.ASZU01000004_gene247 2.24e-07 61.6 COG3409@1|root,COG5632@1|root,COG3409@2|Bacteria,COG5632@2|Bacteria,1V7KT@1239|Firmicutes,4HJ9N@91061|Bacilli,27BVQ@186824|Thermoactinomycetaceae 91061|Bacilli M Ami_2 - - - - - - - - - - - - Amidase_2,DUF3597,PG_binding_1,SH3_5,SPOR k59_122346_1 1379692.S5SXY7_9CIRC 1.44e-31 125.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_253569_1 498761.HM1_2891 4.89e-37 147.0 COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,1TPHP@1239|Firmicutes,24E7K@186801|Clostridia 186801|Clostridia KL Belongs to the N(4) N(6)-methyltransferase family - - - - - - - - - - - - N6_N4_Mtase,ParBc k59_38216_1 1354303.M917_1831 1.8e-88 275.0 COG1401@1|root,COG1401@2|Bacteria,1MYQM@1224|Proteobacteria,1RSU7@1236|Gammaproteobacteria,3NKMU@468|Moraxellaceae 1236|Gammaproteobacteria V AAA domain (dynein-related subfamily) - - - ko:K07452 - - - - ko00000,ko01000,ko02048 - - - AAA_5 k59_6591_2 1344012.ATMI01000031_gene2805 2.4e-08 56.2 2CJWY@1|root,31CWF@2|Bacteria,1RKEF@1224|Proteobacteria,1S75P@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_253578_1 1618242.A0A0C5IBR9_9CIRC 1.16e-38 141.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_47729_1 575540.Isop_2425 5.32e-39 150.0 COG5283@1|root,COG5283@2|Bacteria,2J1F5@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - k59_195690_1 411460.RUMTOR_01335 4.84e-119 414.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_222649_1 1788439.A0A190WHD0_9CIRC 1.98e-22 99.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_122358_1 1122971.BAME01000223_gene6792 7.87e-37 136.0 2DV47@1|root,33TZ6@2|Bacteria,4NT0W@976|Bacteroidetes,2FS1Q@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_31130_1 1220714.L7TK38_9CAUD 2.1e-13 73.2 4QFED@10239|Viruses,4R072@35237|dsDNA viruses no RNA stage,4QPEH@28883|Caudovirales 28883|Caudovirales S tRNA modification - - - - - - - - - - - - - k59_38227_2 1327983.R9ZYX6_9CAUD 4.87e-56 186.0 4QAIJ@10239|Viruses,4QVZ9@35237|dsDNA viruses no RNA stage,4QPXI@28883|Caudovirales,4QNHT@10744|Podoviridae 10744|Podoviridae S C-5 cytosine-specific DNA methylase - - - - - - - - - - - - - k59_6599_1 1379725.S5SYG4_9CIRC 8.18e-44 155.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_96138_2 1399774.JDWH01000035_gene2231 1.41e-15 75.1 2DKZG@1|root,31055@2|Bacteria,1RGC2@1224|Proteobacteria,1S4CP@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_229588_1 1202962.KB907150_gene1502 2.24e-31 114.0 2E645@1|root,330T3@2|Bacteria,1NEGX@1224|Proteobacteria,1SC3K@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Holin of 3TMs, for gene-transfer release - - - - - - - - - - - - GTA_holin_3TM k59_229588_2 521000.PROVRETT_05530 3.78e-26 100.0 COG3179@1|root,COG3179@2|Bacteria,1RE8K@1224|Proteobacteria,1S4U8@1236|Gammaproteobacteria,3Z9BP@586|Providencia 1236|Gammaproteobacteria S D-alanyl-D-alanine carboxypeptidase - - - - - - - - - - - - Peptidase_M15_4 k59_87506_2 1788449.A0A190WHL0_9CIRC 1.06e-23 100.0 4QBFZ@10239|Viruses,4QUKU@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_55776_1 1385658.U5KPZ6_9VIRU 4.17e-120 362.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_13405_1 1609634.A0A0C5AFT2_9VIRU 1.36e-136 397.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_87508_1 1094466.KQS_11905 8.63e-05 50.1 COG5272@1|root,COG5295@1|root,COG5272@2|Bacteria,COG5295@2|Bacteria,4NHCC@976|Bacteroidetes,1I3GX@117743|Flavobacteriia,2NZZ3@237|Flavobacterium 976|Bacteroidetes UW tail collar domain protein - - - - - - - - - - - - Collagen k59_229704_4 1122201.AUAZ01000026_gene1170 7.21e-140 400.0 COG4128@1|root,COG4128@2|Bacteria,1REHG@1224|Proteobacteria,1S491@1236|Gammaproteobacteria,46BRE@72275|Alteromonadaceae 1236|Gammaproteobacteria S Zonular occludens toxin (Zot) - - - - - - - - - - - - Zot k59_253706_1 472759.Nhal_1137 8.5e-38 132.0 COG1403@1|root,COG1403@2|Bacteria,1N6FJ@1224|Proteobacteria 1224|Proteobacteria V HNH endonuclease - - - - - - - - - - - - - k59_6720_1 5691.EAN80025 2.57e-05 51.6 COG0553@1|root,KOG0391@2759|Eukaryota,3XSPY@5653|Kinetoplastida 5653|Kinetoplastida KL helicase - - - - - - - - - - - - Helicase_C,SNF2_N k59_55778_2 697281.Mahau_2909 9.14e-07 55.8 2CK39@1|root,32SBG@2|Bacteria,1V8KG@1239|Firmicutes,249UQ@186801|Clostridia,42IH0@68295|Thermoanaerobacterales 186801|Clostridia S Phage gp6-like head-tail connector protein - - - - - - - - - - - - Phage_connect_1 k59_172184_2 525904.Tter_1630 7.45e-17 78.2 COG2003@1|root,COG2003@2|Bacteria,2NPI9@2323|unclassified Bacteria 2|Bacteria E Belongs to the UPF0758 family radC - - ko:K03630 - - - - ko00000 - - - RadC k59_47877_1 557598.LHK_01497 1.21e-06 48.9 COG5377@1|root,COG5377@2|Bacteria,1QXZ4@1224|Proteobacteria 1224|Proteobacteria L YqaJ-like viral recombinase domain - - - - - - - - - - - - YqaJ k59_47877_2 343509.SG0930 7.83e-25 101.0 COG0629@1|root,COG0629@2|Bacteria,1RC22@1224|Proteobacteria,1S2A9@1236|Gammaproteobacteria 1236|Gammaproteobacteria L ERF superfamily - - - - - - - - - - - - ERF k59_105093_2 1123401.JHYQ01000017_gene2495 1.39e-38 134.0 2E1C1@1|root,32WRT@2|Bacteria,1QUUX@1224|Proteobacteria,1SNVY@1236|Gammaproteobacteria 1236|Gammaproteobacteria S D-alanyl-D-alanine carboxypeptidase - - - - - - - - - - - - Peptidase_M15_4 k59_72239_1 999541.bgla_1g23430 4.35e-11 71.6 COG0305@1|root,COG1372@1|root,COG0305@2|Bacteria,COG1372@2|Bacteria,1MUG9@1224|Proteobacteria,2VIKN@28216|Betaproteobacteria,1K18Q@119060|Burkholderiaceae 28216|Betaproteobacteria L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_179993_1 1788454.A0A190WHE4_9CIRC 3.18e-07 57.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_38431_2 312309.VF_2017 3.14e-38 132.0 2CPEB@1|root,32SIW@2|Bacteria,1MZE0@1224|Proteobacteria,1SARU@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_38431_3 438753.AZC_3586 0.000111 43.5 292MT@1|root,2ZQ5P@2|Bacteria,1PAZF@1224|Proteobacteria,2UYFH@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_163050_1 1469613.JT55_10205 1.15e-10 63.9 2BQ0H@1|root,32IUN@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_55882_1 1347369.CCAD010000083_gene2785 8.26e-09 62.8 COG0464@1|root,COG0464@2|Bacteria,1TQTZ@1239|Firmicutes,4HF00@91061|Bacilli,1ZEYU@1386|Bacillus 91061|Bacilli O ATPase family associated with various cellular activities (AAA) - - - - - - - - - - - - AAA k59_105184_1 45764.G8I4C9_9CAUD 0.000293 48.5 4QAK6@10239|Viruses,4QWNY@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_21565_1 1403819.BATR01000046_gene1341 9.64e-32 120.0 COG0616@1|root,COG0616@2|Bacteria 2|Bacteria OU serine-type peptidase activity sppA - - ko:K04773 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49 k59_188735_1 2003327.CAPSD_BPCHP 3.65e-18 85.5 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_130932_1 1121344.JHZO01000006_gene1818 1.1e-17 85.9 28MKK@1|root,2ZAWR@2|Bacteria,1UYAT@1239|Firmicutes,24GI2@186801|Clostridia,3WR2E@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - RNA_helicase,Viral_Rep k59_212336_1 1120973.AQXL01000124_gene2338 3.83e-05 47.8 COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,4HA3V@91061|Bacilli,278RR@186823|Alicyclobacillaceae 91061|Bacilli K helix_turn_helix, Lux Regulon degU - - ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 M00478 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg k59_172295_1 1120963.KB894501_gene314 2.24e-19 94.4 2DBGR@1|root,2Z95I@2|Bacteria,1RGBI@1224|Proteobacteria,1SBVK@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Bacteriophage replication protein O - - - - - - - - - - - - Phage_rep_O k59_47980_2 1379708.S5SYC3_9CIRC 1.06e-10 69.7 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_237044_1 1096546.WYO_0164 4.66e-42 161.0 COG0749@1|root,COG0749@2|Bacteria,1MWX7@1224|Proteobacteria 1224|Proteobacteria L COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A,DNA_pol_A_exo1 k59_163058_2 106648.BBLJ01000034_gene2601 2.03e-15 72.4 COG0791@1|root,COG0791@2|Bacteria,1QP6S@1224|Proteobacteria,1SIU8@1236|Gammaproteobacteria,3NN30@468|Moraxellaceae 1236|Gammaproteobacteria M NlpC/P60 family - - - - - - - - - - - - NLPC_P60 k59_62980_2 1123487.KB892865_gene1388 1.84e-08 60.1 COG3378@1|root,COG3378@2|Bacteria 2|Bacteria KL Phage plasmid primase P4 family - - - ko:K06919 - - - - ko00000 - - - PriCT_2,Prim-Pol k59_6868_2 690850.Desaf_0705 6.44e-12 67.0 COG4381@1|root,COG4381@2|Bacteria,1N954@1224|Proteobacteria,430E3@68525|delta/epsilon subdivisions,2WVTH@28221|Deltaproteobacteria,2MCQV@213115|Desulfovibrionales 28221|Deltaproteobacteria S Phage protein GP46 - - - - - - - - - - - - GP46 k59_263084_3 78245.Xaut_3722 2.06e-07 54.7 2FEUE@1|root,346TC@2|Bacteria,1MZPB@1224|Proteobacteria,2UC4Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_62981_1 979535.F1D037_9CAUD 2.41e-09 65.9 4QASG@10239|Viruses,4QZZU@35237|dsDNA viruses no RNA stage,4QT37@28883|Caudovirales,4QNXD@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_263195_1 292459.STH3030 1.3e-35 126.0 COG1738@1|root,COG1738@2|Bacteria,1V8R2@1239|Firmicutes,24K5V@186801|Clostridia 186801|Clostridia S ACR, YhhQ family COG1738 - - - ko:K09125 - - - - ko00000 - - - Vut_1 k59_172459_1 1123501.KB902299_gene3817 8.17e-26 117.0 COG2304@1|root,COG2304@2|Bacteria,1QWI7@1224|Proteobacteria,2TY8F@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Putative phage tail protein - - - - - - - - - - - - Phage-tail_3,VWA k59_139218_1 1082932.ATCR1_06806 2.27e-06 54.7 COG3266@1|root,COG3266@2|Bacteria,1QZ8S@1224|Proteobacteria,2URTR@28211|Alphaproteobacteria,4BG0Y@82115|Rhizobiaceae 28211|Alphaproteobacteria M domain, Protein - - - - - - - - - - - - - k59_72482_1 1038867.AXAY01000025_gene2044 8.33e-58 193.0 COG5449@1|root,COG5449@2|Bacteria,1PUMI@1224|Proteobacteria,2U66K@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Uncharacterized conserved protein (DUF2163) - - - - - - - - - - - - DUF2163,Phage_BR0599 k59_72482_2 1038867.AXAY01000025_gene2045 1.18e-15 71.6 2CJX7@1|root,32W32@2|Bacteria,1N82M@1224|Proteobacteria,2UGZ6@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_114595_2 572544.Ilyop_1048 2.24e-16 85.1 COG0863@1|root,COG1475@1|root,COG2189@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,COG2189@2|Bacteria,37AID@32066|Fusobacteria 32066|Fusobacteria L DNA methylase - - - - - - - - - - - - N6_N4_Mtase,ParBc k59_122765_1 1692250.A0A0K1RLR1_9CIRC 3.64e-11 70.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_72486_2 1234888.K0A2R8_9VIRU 3.35e-21 95.1 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_87648_1 742740.HMPREF9474_02267 9.07e-39 137.0 28NM4@1|root,2ZBMQ@2|Bacteria,1V1QD@1239|Firmicutes,24G1B@186801|Clostridia,221N8@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_188941_1 1385658.U5KNR1_9VIRU 9.45e-59 194.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_48122_2 1231377.C426_1976 2.06e-39 140.0 COG0827@1|root,COG0827@2|Bacteria,1UZYQ@1239|Firmicutes,4HWNH@91061|Bacilli 91061|Bacilli L DNA restriction-modification system - - - - - - - - - - - - - k59_48122_4 1335760.ASTG01000033_gene36 1.63e-13 70.1 COG0863@1|root,COG0863@2|Bacteria 2|Bacteria L N-4 methylation of cytosine - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_196027_1 1609634.A0A0C5ANA6_9VIRU 1.61e-18 85.5 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_114607_2 1246445.ANAY01000010_gene1183 0.000125 49.7 COG4122@1|root,COG4122@2|Bacteria,2IC8Z@201174|Actinobacteria 201174|Actinobacteria S Methyltransferase domain - - - - - - - - - - - - Methyltransf_24 k59_38585_1 1385658.U5KPZ6_9VIRU 2.13e-129 388.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_212479_2 1692244.A0A0K1RLR5_9CIRC 4.42e-96 290.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_31608_1 2003327.CAPSD_BPCHP 2.69e-16 84.7 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_205450_1 1692244.A0A0K1RLR5_9CIRC 2.95e-100 301.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_254054_1 1788454.A0A190WHE4_9CIRC 6.69e-41 149.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_7153_1 742725.HMPREF9450_02123 2.16e-26 114.0 COG1196@1|root,COG1196@2|Bacteria,4NMBI@976|Bacteroidetes,2FR6N@200643|Bacteroidia 976|Bacteroidetes D nuclear chromosome segregation - - - - - - - - - - - - - k59_163272_2 1165094.RINTHH_3920 8.23e-14 73.6 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_155847_1 1385658.U5KPZ6_9VIRU 2.69e-73 242.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_122867_1 1420600.W5RNT1_9CIRC 2.19e-28 116.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_223124_1 582744.Msip34_2836 6.56e-68 224.0 COG0464@1|root,COG0464@2|Bacteria,1QU82@1224|Proteobacteria,2WHSD@28216|Betaproteobacteria,2KNN6@206350|Nitrosomonadales 206350|Nitrosomonadales O Zonular occludens toxin (Zot) - - - - - - - - - - - - Zot k59_223124_3 1437882.AZRU01000135_gene1132 0.000423 43.9 2ARMS@1|root,31GYF@2|Bacteria,1QEMU@1224|Proteobacteria,1TBE6@1236|Gammaproteobacteria,1YH9I@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Protein of unknown function (DUF2523) - - - - - - - - - - - - DUF2523 k59_189054_1 665956.HMPREF1032_00688 1.49e-76 243.0 28K55@1|root,2Z9TX@2|Bacteria,1V0P7@1239|Firmicutes,24DCX@186801|Clostridia,3WK99@541000|Ruminococcaceae 186801|Clostridia S Psort location Cytoplasmic, score 7.50 - - - - - - - - - - - - Sipho_Gp37 k59_96566_1 352165.HMPREF7215_2560 1.47e-44 167.0 COG0749@1|root,COG0749@2|Bacteria 2|Bacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity - - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - DNA_pol_A,RNase_H_2 k59_80455_1 1134912.AJTV01000011_gene2535 1.09e-40 155.0 COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,2TQWC@28211|Alphaproteobacteria,36XB0@31993|Methylocystaceae 28211|Alphaproteobacteria L UvrD-like helicase C-terminal domain recD2 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 k59_196106_2 655097.C8ZKD1_9CAUD 4.78e-44 158.0 4QAR1@10239|Viruses,4QUNA@35237|dsDNA viruses no RNA stage,4QPJE@28883|Caudovirales,4QNDS@10744|Podoviridae 10744|Podoviridae S ATPase activity - - - - - - - - - - - - - k59_114833_1 1304865.JAGF01000001_gene344 5.17e-11 72.8 COG3291@1|root,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria 201174|Actinobacteria P PFAM PKD domain containing protein wcoG - - - - - - - - - - - Laminin_G_3,PKD k59_172710_1 1283078.M1IDU1_9CAUD 3.6e-08 59.3 4QBAU@10239|Viruses,4QW8E@35237|dsDNA viruses no RNA stage,4QPEP@28883|Caudovirales,4QNY1@10744|Podoviridae 10744|Podoviridae S viral capsid assembly - - - - - - - - - - - - - k59_230161_1 1524467.IV04_03710 2.32e-14 79.7 COG0582@1|root,COG0582@2|Bacteria,1QZAS@1224|Proteobacteria,1T441@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_integrase k59_56245_1 935565.JAEM01000006_gene3898 3.62e-20 92.8 2C2XN@1|root,32GT6@2|Bacteria,1REZE@1224|Proteobacteria,2U8HW@28211|Alphaproteobacteria 28211|Alphaproteobacteria S PFAM ERF family protein - - - - - - - - - - - - ERF k59_237340_1 462590.A9J4Y6_BPPYU 1.7e-56 207.0 4QAQ9@10239|Viruses,4QUYQ@35237|dsDNA viruses no RNA stage,4QPTV@28883|Caudovirales,4QKRS@10699|Siphoviridae 10699|Siphoviridae S Putative phage tail protein - GO:0005575,GO:0008150,GO:0016032,GO:0018995,GO:0019012,GO:0019058,GO:0019062,GO:0022610,GO:0030430,GO:0033643,GO:0033646,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044403,GO:0044406,GO:0044419,GO:0044650,GO:0051704 - - - - - - - - - - - k59_230162_1 478749.BRYFOR_08514 2.09e-35 125.0 2ARVA@1|root,31H70@2|Bacteria,1V7JT@1239|Firmicutes,24JPE@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - HK97-gp10_like k59_230162_2 742733.HMPREF9469_05020 4.19e-16 80.9 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia,221IX@1506553|Lachnoclostridium 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_7296_1 755731.Clo1100_0230 1.96e-08 60.8 COG0270@1|root,COG0270@2|Bacteria,1TS3G@1239|Firmicutes,249Q9@186801|Clostridia,36GET@31979|Clostridiaceae 186801|Clostridia H PFAM C-5 cytosine-specific DNA methylase dcm - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_13924_1 1379725.S5TMY9_9CIRC 9.46e-38 144.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_163394_1 349123.Lreu23DRAFT_4711 1.31e-06 50.8 COG1476@1|root,COG1476@2|Bacteria,1VEKB@1239|Firmicutes,4HNIW@91061|Bacilli,3F6AB@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain - - - - - - - - - - - - HTH_3 k59_237348_1 691965.D4P7L7_9CAUD 9.83e-29 117.0 4QB9J@10239|Viruses,4QXFE@35237|dsDNA viruses no RNA stage,4QS1Z@28883|Caudovirales,4QN8F@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_212700_3 1609634.A0A0C5AFV4_9VIRU 1e-185 535.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_189221_1 1609634.A0A0C5AFV4_9VIRU 4.62e-110 337.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_114857_1 13735.ENSPSIP00000015528 1.98e-21 98.6 COG0749@1|root,KOG0950@2759|Eukaryota,38BKB@33154|Opisthokonta,3BATG@33208|Metazoa,3CT13@33213|Bilateria,47ZXJ@7711|Chordata,497BB@7742|Vertebrata,4CGP9@8459|Testudines 33208|Metazoa A DNA polymerase theta POLQ GO:0000018,GO:0000724,GO:0000725,GO:0000726,GO:0002200,GO:0002376,GO:0002377,GO:0002440,GO:0002520,GO:0002566,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003684,GO:0003824,GO:0003887,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006282,GO:0006284,GO:0006289,GO:0006302,GO:0006303,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007275,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010569,GO:0010605,GO:0016043,GO:0016445,GO:0016446,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0016829,GO:0016835,GO:0016887,GO:0017111,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031324,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0036297,GO:0042623,GO:0042802,GO:0043142,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0045738,GO:0045910,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0048731,GO:0048856,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051259,GO:0051260,GO:0051575,GO:0051716,GO:0060255,GO:0065003,GO:0065007,GO:0070013,GO:0071704,GO:0071840,GO:0071897,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0097159,GO:0097681,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:2000042,GO:2000779,GO:2000780,GO:2001020,GO:2001021 2.7.7.7 ko:K02349 - - - - ko00000,ko01000,ko03400 - - - DEAD,DNA_pol_A,Helicase_C k59_38815_2 596320.NEIFL0001_2187 8.58e-27 111.0 COG1002@1|root,COG1002@2|Bacteria,1MWRH@1224|Proteobacteria,2VMKD@28216|Betaproteobacteria,2KSBT@206351|Neisseriales 206351|Neisseriales V type II restriction enzyme, methylase - - - - - - - - - - - - N6_Mtase k59_7311_2 105154.Q9MBU2_9VIRU 5.12e-14 72.8 4QDBB@10239|Viruses,4QUM0@29258|ssDNA viruses,4QP4D@10841|Microviridae 10841|Microviridae S Chlamydia-phage Chp2 scaffold (Chlamy_scaf) - - - - - - - - - - - - - k59_223421_3 1234888.K0A2J2_9VIRU 5.77e-111 343.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_14058_2 7719.NP_001027608.1 4.93e-09 60.8 KOG4459@1|root,KOG4459@2759|Eukaryota,38BM6@33154|Opisthokonta,3BB3X@33208|Metazoa,3CSF3@33213|Bilateria,488RE@7711|Chordata 33208|Metazoa S procollagen-proline 3-dioxygenase activity LEPRE1 GO:0001501,GO:0001558,GO:0002791,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005576,GO:0005604,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005783,GO:0005788,GO:0005794,GO:0005886,GO:0006457,GO:0006464,GO:0006807,GO:0007275,GO:0007399,GO:0008150,GO:0008152,GO:0008285,GO:0009058,GO:0009892,GO:0009987,GO:0010605,GO:0010720,GO:0010975,GO:0010976,GO:0012505,GO:0016020,GO:0016043,GO:0016491,GO:0016705,GO:0016706,GO:0017185,GO:0018126,GO:0018193,GO:0018205,GO:0018208,GO:0019222,GO:0019511,GO:0019538,GO:0019797,GO:0019798,GO:0022008,GO:0030154,GO:0030198,GO:0030199,GO:0030278,GO:0030308,GO:0031012,GO:0031323,GO:0031324,GO:0031344,GO:0031346,GO:0031399,GO:0031400,GO:0031543,GO:0031544,GO:0031647,GO:0031974,GO:0032268,GO:0032269,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0032963,GO:0032964,GO:0032991,GO:0036211,GO:0040008,GO:0042127,GO:0043062,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043933,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044421,GO:0044422,GO:0044424,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0044877,GO:0045595,GO:0045597,GO:0045664,GO:0045666,GO:0045926,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050708,GO:0050767,GO:0050769,GO:0050789,GO:0050793,GO:0050794,GO:0050821,GO:0051046,GO:0051049,GO:0051094,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051213,GO:0051223,GO:0051239,GO:0051240,GO:0051246,GO:0051248,GO:0051960,GO:0051962,GO:0055114,GO:0060255,GO:0060284,GO:0060348,GO:0061077,GO:0062023,GO:0065007,GO:0065008,GO:0070013,GO:0070201,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090087,GO:0097435,GO:0120035,GO:0140096,GO:1901564,GO:1901873,GO:1901874,GO:1902494,GO:1903530,GO:2000026 1.14.11.7 ko:K08134,ko:K22459,ko:K22460 - - - - ko00000,ko00535,ko01000,ko03110 - - - 2OG-FeII_Oxy_3 k59_237499_1 640513.Entas_2682 1.72e-16 81.6 COG3566@1|root,COG3566@2|Bacteria,1QWCX@1224|Proteobacteria,1RZS8@1236|Gammaproteobacteria,3X322@547|Enterobacter 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - DUF2213 k59_148467_1 1279017.AQYJ01000014_gene3004 8.79e-46 168.0 COG4733@1|root,COG4733@2|Bacteria,1R77Q@1224|Proteobacteria 1224|Proteobacteria D nuclear chromosome segregation - - - - - - - - - - - - - k59_223423_1 1090134.G5DED7_9CAUD 2.95e-34 136.0 4QHGR@10239|Viruses,4QY9H@35237|dsDNA viruses no RNA stage,4QRCN@28883|Caudovirales,4QIZF@10662|Myoviridae 10662|Myoviridae S nucleic acid binding - - - - - - - - - - - - - k59_38956_1 1469557.JSWF01000025_gene1296 1.94e-17 81.6 COG0603@1|root,COG0603@2|Bacteria,4PF0R@976|Bacteroidetes,1IADP@117743|Flavobacteriia 976|Bacteroidetes F Queuosine biosynthesis protein QueC - - - - - - - - - - - - QueC k59_38956_2 1192868.CAIU01000008_gene967 9.34e-63 198.0 COG1738@1|root,COG1738@2|Bacteria,1RDSF@1224|Proteobacteria 1224|Proteobacteria S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage - - - ko:K09125 - - - - ko00000 - - - Vut_1 k59_189408_1 1197951.I6R9K8_9CAUD 1.17e-124 366.0 4QFIC@10239|Viruses,4QXG2@35237|dsDNA viruses no RNA stage,4QTVA@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_80679_1 1123504.JQKD01000002_gene3911 1.23e-46 159.0 COG4128@1|root,COG4128@2|Bacteria,1REHG@1224|Proteobacteria,2VRK2@28216|Betaproteobacteria,4AEKU@80864|Comamonadaceae 28216|Betaproteobacteria S Zonular occludens toxin (Zot) - - - - - - - - - - - - Zot k59_80679_7 758.BBIX01000008_gene920 1.52e-40 154.0 2CI0W@1|root,2Z81W@2|Bacteria,1R9FZ@1224|Proteobacteria,1S0NA@1236|Gammaproteobacteria,1Y9SV@135625|Pasteurellales 135625|Pasteurellales S Phage X family - - - - - - - - - - - - Phage_CRI,Phage_X k59_254345_1 1463926.JOCA01000002_gene5839 3.49e-29 116.0 COG0553@1|root,COG0553@2|Bacteria,2IC31@201174|Actinobacteria 201174|Actinobacteria KL Superfamily II DNA RNA helicases, SNF2 family - - - - - - - - - - - - SNF2_N k59_237502_4 753084.F4YCI4_9CAUD 1.93e-53 189.0 4QAIK@10239|Viruses,4QUPH@35237|dsDNA viruses no RNA stage,4QS4V@28883|Caudovirales,4QKNC@10699|Siphoviridae 10699|Siphoviridae S hydrolase activity - - - - - - - - - - - - - k59_105748_1 2003327.CAPSD_BPCHP 3.42e-77 253.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_246049_3 1123261.AXDW01000009_gene65 5.9e-06 53.5 COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,1RY7A@1236|Gammaproteobacteria,1X53I@135614|Xanthomonadales 135614|Xanthomonadales H Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway bioC - 2.1.1.197 ko:K02169 ko00780,ko01100,map00780,map01100 M00572 R09543 RC00003,RC00460 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11 k59_246049_5 521674.Plim_1055 4.12e-07 59.7 COG0463@1|root,COG1216@1|root,COG2227@1|root,COG4641@1|root,COG5010@1|root,COG0463@2|Bacteria,COG1216@2|Bacteria,COG2227@2|Bacteria,COG4641@2|Bacteria,COG5010@2|Bacteria,2J07E@203682|Planctomycetes 203682|Planctomycetes M Glycosyl transferase family 2 - - - - - - - - - - - - Glyco_trans_1_2,Glycos_transf_2,Methyltransf_23,TPR_16,TPR_19,TPR_7,TPR_8 k59_212829_2 1230341.MJ3_13664 7.77e-17 85.5 COG0739@1|root,COG5280@1|root,COG5412@1|root,COG0739@2|Bacteria,COG5280@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,4HAFE@91061|Bacilli 91061|Bacilli M Phage tail tape measure protein - - - - - - - - - - - - Peptidase_M23,PhageMin_Tail,SLT k59_39035_1 1477404.A0A023NH90_9CAUD 5.29e-107 335.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_131495_2 1304878.AUGD01000009_gene6429 1.62e-32 133.0 COG3723@1|root,COG3723@2|Bacteria,1R6DB@1224|Proteobacteria,2U82T@28211|Alphaproteobacteria,3K2R8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L RecT family - - - ko:K07455 - - - - ko00000,ko03400 - - - RecT k59_263720_1 1125725.HMPREF1325_1318 3.04e-11 62.4 2ANIJ@1|root,31DHJ@2|Bacteria,2JAIW@203691|Spirochaetes 203691|Spirochaetes - - - - - - - - - - - - - - - k59_72981_1 484022.Fphi_1619 6.32e-28 114.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,1RMPV@1236|Gammaproteobacteria,4606X@72273|Thiotrichales 72273|Thiotrichales F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdA - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN k59_72981_4 5286.M7WKD9 2.12e-06 55.1 COG1223@1|root,KOG0742@2759|Eukaryota,38HPN@33154|Opisthokonta,3NU7H@4751|Fungi,3V04M@5204|Basidiomycota 4751|Fungi O P-loop containing nucleoside triphosphate hydrolase protein - - - - - - - - - - - - AAA k59_105832_1 1385658.U5KPZ6_9VIRU 4.42e-193 555.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_263722_1 1380894.S5TR92_9CIRC 1.56e-09 61.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_196443_2 521095.Apar_0768 1.72e-07 52.4 COG1327@1|root,COG1327@2|Bacteria,2IHU9@201174|Actinobacteria,4CVYF@84998|Coriobacteriia 84998|Coriobacteriia K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes nrdR - - ko:K07738 - - - - ko00000,ko03000 - - - ATP-cone k59_173054_1 1197951.I6S2A9_9CAUD 9.46e-49 174.0 4QCM5@10239|Viruses,4QVZY@35237|dsDNA viruses no RNA stage,4QQFH@28883|Caudovirales 28883|Caudovirales S Bacteriophage head to tail connecting protein - GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019028,GO:0019058,GO:0019068,GO:0019072,GO:0019073,GO:0032991,GO:0044403,GO:0044419,GO:0044423,GO:0046798,GO:0051704 - - - - - - - - - - - k59_223552_1 428125.CLOLEP_01375 2.11e-72 246.0 2EWZQ@1|root,33QB0@2|Bacteria,1V0T1@1239|Firmicutes,249Z2@186801|Clostridia,3WNBH@541000|Ruminococcaceae 186801|Clostridia S DNA polymerase type-B family - - - - - - - - - - - - - k59_189649_1 926569.ANT_21170 1.72e-47 164.0 COG4974@1|root,COG4974@2|Bacteria,2G8U5@200795|Chloroflexi 200795|Chloroflexi L Belongs to the 'phage' integrase family - - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_4,Phage_integrase k59_115247_1 76869.PputGB1_1755 1.4e-05 53.5 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,1RR0M@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_237667_1 1692253.A0A0K1RLM4_9CIRC 1.26e-27 118.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_131544_1 466088.CL42_02065 1.14e-79 246.0 COG0270@1|root,COG0270@2|Bacteria,1N0XD@1224|Proteobacteria,1T05A@1236|Gammaproteobacteria 1236|Gammaproteobacteria L C-5 cytosine-specific DNA methylase - - - - - - - - - - - - DNA_methylase k59_105907_1 105154.Q9MBU6_9VIRU 6.88e-36 135.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_263837_1 1270196.JCKI01000013_gene3205 4.79e-24 103.0 28IN7@1|root,2Z8NM@2|Bacteria,4NHTH@976|Bacteroidetes 976|Bacteroidetes S Capsid protein (F protein) - - - - - - - - - - - - Phage_F k59_56623_1 1618238.A0A0C5IB41_9CIRC 2.71e-48 169.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_223655_3 1117318.PRUB_08799 9.56e-13 64.7 COG3772@1|root,COG3772@2|Bacteria,1N0ZQ@1224|Proteobacteria,1S9AE@1236|Gammaproteobacteria,2Q38I@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S Phage lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_39151_1 105154.Q9MBU6_9VIRU 1.29e-25 105.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_88038_1 186617.M9M8L2_9VIRU 1.03e-26 113.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_256210_1 1392490.JHZX01000001_gene2419 5.07e-45 161.0 28NS6@1|root,2ZBR8@2|Bacteria,4NMPZ@976|Bacteroidetes,1I1IF@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_40736_1 767434.Fraau_2947 1.83e-19 100.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1X4KE@135614|Xanthomonadales 135614|Xanthomonadales L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_239435_1 338966.Ppro_2452 2.76e-44 168.0 28K3I@1|root,2Z9SN@2|Bacteria,1MU2M@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_24265_1 1234888.K0A2J2_9VIRU 2.84e-101 314.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_82522_1 575605.ACQN01000014_gene1324 2.08e-31 133.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,4H9S7@91061|Bacilli,3F3ZA@33958|Lactobacillaceae 91061|Bacilli L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A k59_198346_3 411468.CLOSCI_00917 2.3e-24 96.3 2A2ID@1|root,30QVY@2|Bacteria,1V4BJ@1239|Firmicutes,24JG2@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_247640_1 1316739.R4JE08_9CAUD 0.000244 49.3 4QFSQ@10239|Viruses,4R063@35237|dsDNA viruses no RNA stage,4QT6M@28883|Caudovirales,4QP2G@10744|Podoviridae 10744|Podoviridae S ligase activity - - - - - - - - - - - - - k59_89132_5 10872.VG301_BPPF3 2.18e-45 164.0 4QBME@10239|Viruses,4QUKP@29258|ssDNA viruses,4QP4G@10860|Inoviridae 10860|Inoviridae S Zonular occludens toxin (Zot) - - - - - - - - - - - - - k59_165613_6 1347393.HG726025_gene2725 2.83e-20 85.1 28P3F@1|root,30H2V@2|Bacteria,4NNJK@976|Bacteroidetes,2G38T@200643|Bacteroidia,4AWBV@815|Bacteroidaceae 976|Bacteroidetes - - - - - - - - - - - - - - - k59_82707_1 888743.HMPREF9141_0984 0.000468 49.3 2EVUA@1|root,33P81@2|Bacteria,4P82D@976|Bacteroidetes,2FV68@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_65348_1 1298880.AUEV01000019_gene523 0.000114 46.2 COG1396@1|root,COG1396@2|Bacteria,2GPWH@201174|Actinobacteria 201174|Actinobacteria K transcriptional regulator - - - - - - - - - - - - Cupin_2,HTH_3,HTH_31 k59_182435_2 1234888.K0A2J2_9VIRU 3.39e-169 493.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_98575_1 469660.A8HNV9_9CAUD 8.1e-09 63.2 4QBTM@10239|Viruses,4QWCV@35237|dsDNA viruses no RNA stage,4QRTG@28883|Caudovirales,4QNB6@10744|Podoviridae 10744|Podoviridae S Methyltransferase small domain - - - - - - - - - - - - - k59_214802_1 1385658.U5KPZ6_9VIRU 1.79e-93 293.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_239695_1 1211777.BN77_4169 9.22e-63 204.0 2C5GI@1|root,2Z8C1@2|Bacteria,1R8XM@1224|Proteobacteria,2TUME@28211|Alphaproteobacteria,4BJKS@82115|Rhizobiaceae 28211|Alphaproteobacteria S P22 coat protein - gene protein 5 - - - - - - - - - - - - P22_CoatProtein k59_98580_1 765869.BDW_04410 7.83e-05 54.3 COG3210@1|root,COG3210@2|Bacteria,1NED3@1224|Proteobacteria,42WDX@68525|delta/epsilon subdivisions,2MTVC@213481|Bdellovibrionales,2WRDH@28221|Deltaproteobacteria 213481|Bdellovibrionales U cell wall surface anchor family protein - - - - - - - - - - - - Peptidase_S74 k59_50050_76 309807.SRU_1772 2.14e-114 341.0 COG1087@1|root,COG1087@2|Bacteria,4NEM9@976|Bacteroidetes,1FJIC@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes M Polysaccharide biosynthesis protein galE - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd k59_50050_77 926550.CLDAP_36340 4.43e-128 375.0 COG2605@1|root,COG2605@2|Bacteria,2G5TF@200795|Chloroflexi 200795|Chloroflexi S PFAM GHMP kinase - - 2.7.1.168 ko:K07031 ko00540,map00540 - R09770 RC00002,RC00078 ko00000,ko00001,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N k59_50050_78 926569.ANT_15770 1.27e-47 166.0 COG0279@1|root,COG2203@1|root,COG0279@2|Bacteria,COG2203@2|Bacteria,2G6QD@200795|Chloroflexi 200795|Chloroflexi G Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate - - 5.3.1.28 ko:K03271 ko00540,ko01100,map00540,map01100 M00064 R05645,R09768,R09769 RC00434 ko00000,ko00001,ko00002,ko01000,ko01005 - - - SIS_2 k59_50050_79 867845.KI911784_gene2901 2.99e-41 144.0 COG0241@1|root,COG0241@2|Bacteria,2G6V8@200795|Chloroflexi,375WG@32061|Chloroflexia 32061|Chloroflexia E TIGRFAM histidinol-phosphate phosphatase family protein - - 3.1.3.82,3.1.3.83 ko:K03273 ko00540,ko01100,map00540,map01100 M00064 R05647,R09771 RC00017 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Hydrolase_like k59_50050_80 1397699.JNIS01000001_gene2765 1.15e-14 75.9 COG0739@1|root,COG3103@1|root,COG0739@2|Bacteria,COG3103@2|Bacteria,1TRWJ@1239|Firmicutes,4HWZ3@91061|Bacilli 91061|Bacilli MT peptidase - - - - - - - - - - - - Peptidase_M23,SH3_3 k59_50050_87 759914.BP951000_1469 7.84e-24 115.0 COG5283@1|root,COG5283@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - PhageMin_Tail k59_25364_1 1452718.JBOY01000021_gene715 5.64e-54 186.0 COG0553@1|root,COG0553@2|Bacteria 2|Bacteria L helicase activity - - - - - - - - - - - - Helicase_C,SNF2_N k59_41887_1 1279017.AQYJ01000017_gene1392 4.94e-53 176.0 2E16H@1|root,32WMB@2|Bacteria,1N6EU@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_41887_2 1279017.AQYJ01000026_gene6 3.2e-42 143.0 COG3108@1|root,COG3108@2|Bacteria,1NMU6@1224|Proteobacteria 1224|Proteobacteria S Peptidase M15 - - - - - - - - - - - - Peptidase_M15_3 k59_124866_3 77635.BISU_0470 4.92e-05 52.4 28MKK@1|root,2ZAWR@2|Bacteria,2IS2W@201174|Actinobacteria,4D1DD@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - RNA_helicase,Viral_Rep k59_75060_3 1379714.S5TND6_9CIRC 1.7e-56 193.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_141347_2 1385658.U5KNR1_9VIRU 4.64e-49 171.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_224246_1 1609634.A0A0C5AFV4_9VIRU 1.93e-93 295.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_224246_7 2003327.CAPSD_BPCHP 8.96e-44 160.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_249200_2 1609634.A0A0C5AFV4_9VIRU 3.53e-75 253.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_216028_1 396595.TK90_1231 5.72e-15 73.6 COG3756@1|root,COG3756@2|Bacteria,1QW2K@1224|Proteobacteria,1S1C7@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - - k59_207668_1 1121440.AUMA01000012_gene1362 3.44e-61 209.0 COG5323@1|root,COG5323@2|Bacteria,1R049@1224|Proteobacteria,42UYF@68525|delta/epsilon subdivisions,2WQN3@28221|Deltaproteobacteria,2M90K@213115|Desulfovibrionales 28221|Deltaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6 k59_207668_2 156889.Mmc1_1012 9.38e-103 335.0 COG2268@1|root,COG2268@2|Bacteria,1NT13@1224|Proteobacteria,2U335@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Band 7 protein - - - - - - - - - - - - - k59_207668_4 1132836.RCCGE510_03078 7.87e-11 70.9 2E5FK@1|root,3307A@2|Bacteria,1N95D@1224|Proteobacteria,2UJ05@28211|Alphaproteobacteria,4B8UG@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_207668_7 49964.Q94MS1_9CAUD 1.05e-133 389.0 4QB4H@10239|Viruses,4QYQI@35237|dsDNA viruses no RNA stage,4QUAR@28883|Caudovirales,4QNUV@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_133148_2 1357399.HMPREF2087_00488 1.66e-09 63.9 COG2520@1|root,COG2520@2|Bacteria,1N28Y@1224|Proteobacteria,43BVD@68525|delta/epsilon subdivisions 1224|Proteobacteria J Methyltransferase FkbM domain - - - - - - - - - - - - Methyltransf_21 k59_116490_1 428125.CLOLEP_01823 2.55e-16 83.6 COG5377@1|root,COG5377@2|Bacteria,1TS2Y@1239|Firmicutes,249SB@186801|Clostridia,3WKYR@541000|Ruminococcaceae 186801|Clostridia L YqaJ viral recombinase family - - - - - - - - - - - - YqaJ k59_116490_2 760568.Desku_0904 9.47e-26 112.0 2EI39@1|root,33BUS@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_116490_3 1396418.BATQ01000046_gene6174 7.24e-14 75.1 2CHG1@1|root,32YZS@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_116490_8 335543.Sfum_1872 1.68e-19 85.9 2AD08@1|root,312N7@2|Bacteria,1NDC4@1224|Proteobacteria,42VQI@68525|delta/epsilon subdivisions,2WS8T@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Holin of 3TMs, for gene-transfer release - - - - - - - - - - - - GTA_holin_3TM k59_116490_11 1346330.M472_21355 9.74e-30 112.0 2DMYE@1|root,32UDK@2|Bacteria,4P1A5@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - k59_75124_2 1453501.JELR01000001_gene2539 1.07e-27 102.0 2EU41@1|root,33MKV@2|Bacteria,1NJ1A@1224|Proteobacteria,1SGWK@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Regulatory protein - - - - - - - - - - - - YdaS_antitoxin k59_75124_3 1453501.JELR01000001_gene2538 1.85e-09 57.0 COG4643@1|root,COG4643@2|Bacteria,1MVGY@1224|Proteobacteria,1S7S5@1236|Gammaproteobacteria,46AWU@72275|Alteromonadaceae 1236|Gammaproteobacteria S Toprim domain - - - ko:K06919 - - - - ko00000 - - - PriCT_2,Toprim_3,Toprim_4 k59_249228_1 269797.Mbar_A2783 0.000291 53.5 COG3291@1|root,arCOG02515@1|root,arCOG02527@1|root,arCOG02510@2157|Archaea,arCOG02515@2157|Archaea,arCOG02527@2157|Archaea,2Y7RP@28890|Euryarchaeota,2NBKZ@224756|Methanomicrobia 224756|Methanomicrobia S Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - - - - - - - - - - CARDB,DUF3344,PKD k59_191683_1 1452718.JBOY01000137_gene1485 4.41e-80 261.0 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1NKZK@1224|Proteobacteria,1S4YH@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C k59_26257_1 1316932.MHH_c08320 6.69e-66 221.0 COG2801@1|root,COG2801@2|Bacteria,1MXCK@1224|Proteobacteria,1RV69@1236|Gammaproteobacteria,1Y9ID@135625|Pasteurellales 135625|Pasteurellales L Mu transposase, C-terminal - - - ko:K07497 - - - - ko00000 - - - HTH_28,HTH_Tnp_Mu_2,Mu-transpos_C,rve k59_142312_1 1476583.DEIPH_ctg011orf0055 1.51e-34 134.0 COG1475@1|root,COG1475@2|Bacteria 2|Bacteria K chromosome segregation - - - - - - - - - - - - ParBc k59_200108_1 211586.SO_2958 0.000416 45.4 2DNB5@1|root,32WIW@2|Bacteria,1N0BM@1224|Proteobacteria,1S8UT@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Bacteriophage HK97-gp10, putative tail-component - - - - - - - - - - - - HK97-gp10_like k59_208286_1 608538.HTH_0543 3.32e-17 89.4 COG5362@1|root,COG5362@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Terminase_6C k59_100733_2 490913.C4NTG0_9CAUD 4.89e-108 324.0 4QFVM@10239|Viruses,4QZ9I@35237|dsDNA viruses no RNA stage,4QRXV@28883|Caudovirales,4QNS4@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_241632_2 1121459.AQXE01000001_gene2745 4.01e-12 71.6 COG3170@1|root,COG3170@2|Bacteria,1Q45C@1224|Proteobacteria,42Z4T@68525|delta/epsilon subdivisions,2WTRW@28221|Deltaproteobacteria,2MA4T@213115|Desulfovibrionales 28221|Deltaproteobacteria NU Tfp pilus assembly protein FimV - - - - - - - - - - - - - k59_117438_1 1609634.A0A0C5AFV4_9VIRU 3.13e-126 375.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_117438_2 1609634.A0A0C5ANA6_9VIRU 6.36e-11 67.8 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_26329_2 1123487.KB892865_gene1389 3.29e-56 186.0 2DKZ2@1|root,32UFZ@2|Bacteria,1N5GS@1224|Proteobacteria 1224|Proteobacteria S PD-(D/E)XK nuclease superfamily - - - - - - - - - - - - PDDEXK_1 k59_142407_1 1188256.BASI01000007_gene2308 5.63e-07 57.4 COG0338@1|root,COG0338@2|Bacteria 2|Bacteria L D12 class N6 adenine-specific DNA methyltransferase - - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 k59_9384_7 1121921.KB898706_gene3045 1.11e-70 240.0 28MJ5@1|root,2ZAVR@2|Bacteria,1R5CR@1224|Proteobacteria,1SCPR@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage stabilisation protein - - - - - - - - - - - - Phage_stabilise k59_9384_11 10761.Q716H0_BPSFV 1.59e-101 315.0 4QBD3@10239|Viruses,4QXFU@35237|dsDNA viruses no RNA stage,4QQ7Z@28883|Caudovirales,4QNJ0@10744|Podoviridae 10744|Podoviridae S P22 coat protein - gene protein 5 - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0008150,GO:0009987,GO:0016032,GO:0016043,GO:0019012,GO:0019028,GO:0019030,GO:0019058,GO:0019068,GO:0019069,GO:0019075,GO:0022607,GO:0039620,GO:0042802,GO:0042803,GO:0044085,GO:0044403,GO:0044419,GO:0044423,GO:0046729,GO:0046797,GO:0046983,GO:0051704,GO:0071840 - - - - - - - - - - - k59_9384_17 1123399.AQVE01000045_gene3190 4.74e-101 318.0 COG1783@1|root,COG1783@2|Bacteria,1R66A@1224|Proteobacteria,1RQFD@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage terminase, large subunit Z012_12305 - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C k59_134027_2 105154.Q9MBU2_9VIRU 1.75e-14 73.9 4QDBB@10239|Viruses,4QUM0@29258|ssDNA viruses,4QP4D@10841|Microviridae 10841|Microviridae S Chlamydia-phage Chp2 scaffold (Chlamy_scaf) - - - - - - - - - - - - - k59_109001_1 314278.NB231_04115 4.33e-10 65.1 COG2227@1|root,COG2227@2|Bacteria,1MZ3S@1224|Proteobacteria 1224|Proteobacteria H 3-demethylubiquinone-9 3-O-methyltransferase activity - - - - - - - - - - - - Methyltransf_23 k59_183590_1 698761.RTCIAT899_CH12160 3.39e-17 92.8 COG4409@1|root,COG4409@2|Bacteria,1PGPV@1224|Proteobacteria,2V361@28211|Alphaproteobacteria,4BK71@82115|Rhizobiaceae 28211|Alphaproteobacteria G exo-alpha-(2->6)-sialidase activity - - - - - - - - - - - - - k59_10155_2 1235793.C809_01928 1.94e-12 72.4 COG1196@1|root,COG4487@1|root,COG5283@1|root,COG1196@2|Bacteria,COG4487@2|Bacteria,COG5283@2|Bacteria,1UP89@1239|Firmicutes 1239|Firmicutes D nuclear chromosome segregation - - - - - - - - - - - - - k59_52047_1 1231190.NA8A_18192 3.2e-10 59.3 COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,2TU8N@28211|Alphaproteobacteria,43KT4@69277|Phyllobacteriaceae 28211|Alphaproteobacteria L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_109934_3 115711.CP_0543 1.46e-14 75.1 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_109934_5 1609634.A0A0C5AFV4_9VIRU 2.16e-137 412.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_250565_1 115991.K0NVY8_9CAUD 4.85e-17 86.7 4QAZ6@10239|Viruses,4QUU8@35237|dsDNA viruses no RNA stage,4QPHV@28883|Caudovirales,4QI4H@10662|Myoviridae 10662|Myoviridae S Phage tail sheath protein - GO:0005575,GO:0019012,GO:0044423,GO:0098015,GO:0098027 - - - - - - - - - - - k59_59941_1 105154.Q9MBU6_9VIRU 1.48e-22 102.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_159403_2 1234888.K0A2J2_9VIRU 3.58e-54 186.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_35267_1 745310.G432_17125 2.89e-11 66.6 COG5449@1|root,COG5449@2|Bacteria,1MXK2@1224|Proteobacteria,2TTWS@28211|Alphaproteobacteria,2JZW7@204457|Sphingomonadales 204457|Sphingomonadales S Phage conserved hypothetical protein BR0599 - - - - - - - - - - - - DUF2163,Phage_BR0599 k59_35267_2 991905.SL003B_4035 2.44e-06 48.9 COG0791@1|root,COG0791@2|Bacteria 2|Bacteria M cysteine-type peptidase activity - - - - - - - - - - - - NLPC_P60 k59_135053_1 936136.ARRT01000006_gene5340 3.66e-35 136.0 COG1783@1|root,COG1783@2|Bacteria,1RAGC@1224|Proteobacteria,2U6JF@28211|Alphaproteobacteria,4BID4@82115|Rhizobiaceae 28211|Alphaproteobacteria S phage Terminase large subunit - - - - - - - - - - - - - k59_109945_1 1485544.JQKP01000011_gene745 1.13e-11 65.9 2E645@1|root,330T3@2|Bacteria,1NEGX@1224|Proteobacteria,2VY99@28216|Betaproteobacteria 28216|Betaproteobacteria S Holin of 3TMs, for gene-transfer release - - - - - - - - - - - - GTA_holin_3TM k59_242473_2 1618238.A0A0C5IB41_9CIRC 1.86e-22 103.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_43634_66 1121864.OMO_01316 1.26e-60 235.0 COG5283@1|root,COG5283@2|Bacteria,1UHQM@1239|Firmicutes,4HEHJ@91061|Bacilli 91061|Bacilli D Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_43634_76 67267.JNXT01000054_gene2989 5.61e-17 94.7 2F1HE@1|root,33UHX@2|Bacteria,2IH41@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_43634_86 1437603.BMON_0140 0.000101 53.5 2C9AC@1|root,2Z7TR@2|Bacteria,2I07F@201174|Actinobacteria,4D2I2@85004|Bifidobacteriales 201174|Actinobacteria S Phage portal protein, SPP1 Gp6-like - - - - - - - - - - - - Phage_prot_Gp6 k59_127604_1 1300005.R9RFD1_9CAUD 9.66e-08 60.5 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales 28883|Caudovirales S N-acetylmuramoyl-L-alanine amidase activity - - - - - - - - - - - - - k59_160078_1 1123020.AUIE01000007_gene3229 1.67e-41 145.0 2CJWY@1|root,31CWF@2|Bacteria,1RKEF@1224|Proteobacteria,1S75P@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_160078_2 76114.ebA5483 2.88e-25 98.6 COG5614@1|root,COG5614@2|Bacteria,1N9Y5@1224|Proteobacteria,2VY82@28216|Betaproteobacteria 28216|Betaproteobacteria S head-tail adaptor - - - - - - - - - - - - Phage_H_T_join k59_102322_1 504346.TMP_BPPAJ 1.57e-20 95.9 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - GO:0008150,GO:0044403,GO:0044409,GO:0044411,GO:0044419,GO:0051701,GO:0051704,GO:0051828,GO:0051830,GO:0085027 - - - - - - - - - - - k59_176837_1 1453501.JELR01000001_gene2516 9.47e-07 57.8 COG4733@1|root,COG4926@1|root,COG4733@2|Bacteria,COG4926@2|Bacteria,1R77Q@1224|Proteobacteria,1S1WT@1236|Gammaproteobacteria,469QU@72275|Alteromonadaceae 1236|Gammaproteobacteria S Fibronectin type 3 domain - - - - - - - - - - - - - k59_69192_2 1123487.KB892865_gene1380 1.39e-28 121.0 COG3170@1|root,COG3170@2|Bacteria,1PMRK@1224|Proteobacteria,2W7ZG@28216|Betaproteobacteria,2KZB6@206389|Rhodocyclales 206389|Rhodocyclales NU Tfp pilus assembly protein FimV - - - - - - - - - - - - - k59_127712_1 102125.Xen7305DRAFT_00050870 2.1e-16 81.3 COG1442@1|root,COG1442@2|Bacteria,1G8UX@1117|Cyanobacteria 1117|Cyanobacteria M Tetratricopeptide repeat - - - - - - - - - - - - Glyco_transf_8 k59_219264_1 1379724.S5T6B0_9CIRC 6.69e-36 134.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_209681_1 1121459.AQXE01000001_gene2744 8.43e-17 87.8 COG5164@1|root,COG5164@2|Bacteria,1N2FU@1224|Proteobacteria,42WNM@68525|delta/epsilon subdivisions,2WRNC@28221|Deltaproteobacteria 28221|Deltaproteobacteria K Collagen triple helix repeat (20 copies) - - - - - - - - - - - - - k59_85147_2 1283077.M1I7J8_9CAUD 8.31e-87 280.0 4QCWX@10239|Viruses,4QW0V@35237|dsDNA viruses no RNA stage,4QR4Y@28883|Caudovirales,4QP36@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_85147_3 49964.Q94MS4_9CAUD 1.03e-136 425.0 4QCUF@10239|Viruses,4QV7U@35237|dsDNA viruses no RNA stage,4QQ89@28883|Caudovirales,4QNCY@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_85147_8 49964.Q94MS1_9CAUD 2.04e-127 374.0 4QB4H@10239|Viruses,4QYQI@35237|dsDNA viruses no RNA stage,4QUAR@28883|Caudovirales,4QNUV@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_85147_13 49964.Q94MR7_9CAUD 3.37e-97 312.0 4QERB@10239|Viruses,4R014@35237|dsDNA viruses no RNA stage,4QTGJ@28883|Caudovirales,4QNZG@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_85147_17 1526550.A0A088F6W1_9VIRU 6.49e-05 53.9 4QAK6@10239|Viruses 10239|Viruses S N-acetylmuramoyl-L-alanine amidase activity - - - - - - - - - - - - - k59_85147_19 399742.Ent638_3484 5.45e-09 66.6 COG5301@1|root,COG5301@2|Bacteria,1MWNN@1224|Proteobacteria,1RR74@1236|Gammaproteobacteria,3X0Z6@547|Enterobacter 1236|Gammaproteobacteria S tail collar domain protein H - - - - - - - - - - - Collar,DUF3751,Phage_fiber_2 k59_85147_20 279383.Q5DN17_9CAUD 2.99e-10 73.2 4QBUC@10239|Viruses,4QVRG@35237|dsDNA viruses no RNA stage,4QQGQ@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_85147_26 658187.LDG_6143 1.09e-20 106.0 COG0467@1|root,COG1119@1|root,COG0467@2|Bacteria,COG1119@2|Bacteria 2|Bacteria P ATPase activity - - - ko:K03546,ko:K06919,ko:K07452,ko:K08482,ko:K09384,ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko01000,ko02042,ko02048,ko03400 - - - AAA_11,AAA_12,AAA_25,DUF4011 k59_85147_27 742740.HMPREF9474_01234 1.66e-65 235.0 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,2487V@186801|Clostridia,221Y2@1506553|Lachnoclostridium 186801|Clostridia L COG COG0749 DNA polymerase I - 3-5 exonuclease and polymerase domains - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_85147_30 585501.HMPREF6123_0853 1.9e-17 91.3 COG2887@1|root,COG2887@2|Bacteria,1TPIC@1239|Firmicutes,247TB@186801|Clostridia,2PS99@265975|Oribacterium 186801|Clostridia L Protein of unknown function (DUF2800) - - - - - - - - - - - - DUF2800 k59_85147_36 663278.Ethha_1823 2.35e-58 206.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,3WH0A@541000|Ruminococcaceae 186801|Clostridia L helicase - - - - - - - - - - - - Helicase_C,SNF2_N k59_85147_41 402612.FP2177 1.17e-29 117.0 COG0714@1|root,COG0714@2|Bacteria,4NJMT@976|Bacteroidetes,1HZMP@117743|Flavobacteriia 976|Bacteroidetes S AAA domain (dynein-related subfamily) - - 6.6.1.2 ko:K09882 ko00860,ko01100,map00860,map01100 - R05227 RC02000 ko00000,ko00001,ko01000 - - - AAA_5 k59_185198_1 1283287.KB822575_gene553 2.92e-15 90.5 COG1472@1|root,COG3942@1|root,COG1472@2|Bacteria,COG3942@2|Bacteria,2GJ5H@201174|Actinobacteria,4DTG7@85009|Propionibacteriales 201174|Actinobacteria G Carbohydrate binding domain (family 11) - - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - Big_3_5,CBM_11,Calx-beta,F5_F8_type_C,Glyco_hydro_3,Glyco_hydro_3_C k59_45734_1 46234.ANA_C12634 7.56e-08 60.1 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Glyco_trans_1_4,Glycos_transf_1,Sulfotransfer_2 k59_78664_2 1196322.A370_02072 7.46e-20 88.2 COG3723@1|root,COG3723@2|Bacteria,1UNDF@1239|Firmicutes,24ECD@186801|Clostridia,36HN4@31979|Clostridiaceae 186801|Clostridia L RecT family - - - ko:K07455 - - - - ko00000,ko03400 - - - RecT k59_244072_1 1692244.A0A0K1RLR5_9CIRC 7.06e-89 271.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_252194_2 260827.Q6R6A4_9CAUD 4.57e-42 162.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales 28883|Caudovirales S N-methyltransferase activity - - - - - - - - - - - - - k59_210656_5 1120936.KB907208_gene1107 2.44e-79 256.0 COG0209@1|root,COG0209@2|Bacteria,2IC1H@201174|Actinobacteria 201174|Actinobacteria F Ribonucleotide reductase, barrel domain - - - - - - - - - - - - Ribonuc_red_lgC k59_220734_1 768710.DesyoDRAFT_1130 3.48e-05 53.5 COG5301@1|root,COG5301@2|Bacteria,1UZU2@1239|Firmicutes,24EJ3@186801|Clostridia 186801|Clostridia S Protein of unknown function (DUF2793) - - - - - - - - - - - - DUF2793 k59_136945_1 1477404.A0A023NFX4_9CAUD 3.48e-24 107.0 4QAXA@10239|Viruses,4QYJI@35237|dsDNA viruses no RNA stage,4QQ1A@28883|Caudovirales,4QNU7@10744|Podoviridae 10744|Podoviridae S metallopeptidase activity - - - - - - - - - - - - - k59_103339_5 742733.HMPREF9469_05011 3.07e-32 115.0 2BT3T@1|root,30VXX@2|Bacteria,1U239@1239|Firmicutes,25JN1@186801|Clostridia,2232Q@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_103339_10 1463881.KL591003_gene5860 1.02e-10 67.8 COG1293@1|root,COG5283@1|root,COG1293@2|Bacteria,COG5283@2|Bacteria,2I92I@201174|Actinobacteria 201174|Actinobacteria M Phage tail tape measure protein, TP901 family - - - - - - - - - - - - PhageMin_Tail k59_210661_2 1234888.K0A2J2_9VIRU 2.21e-43 159.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_153716_1 645099.MREP_BBTVA 9.76e-07 53.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_194252_2 1049564.TevJSym_aa00340 1.51e-49 162.0 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria,1J5PI@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_194252_4 573.JG24_10890 8.24e-27 101.0 2CH99@1|root,32S5M@2|Bacteria,1N2GH@1224|Proteobacteria,1T0UT@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Recombination enhancement, RecA-dependent nuclease - - - - - - - - - - - - RecA_dep_nuc k59_194252_9 1205681.CALW02000096_gene1175 3.15e-07 54.3 COG0358@1|root,COG0358@2|Bacteria,1R5JV@1224|Proteobacteria,2TW8V@28211|Alphaproteobacteria,48UK0@772|Bartonellaceae 28211|Alphaproteobacteria L Toprim domain - - - - - - - - - - - - Toprim_3 k59_29384_2 1028800.RG540_CH13830 6.09e-36 134.0 2DUXE@1|root,312CE@2|Bacteria,1PQIE@1224|Proteobacteria,2V2XC@28211|Alphaproteobacteria,4BJT8@82115|Rhizobiaceae 28211|Alphaproteobacteria S Phage T7 capsid assembly protein - - - - - - - - - - - - Phage_T7_Capsid k59_233897_1 888060.HMPREF9081_1674 1.95e-32 130.0 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,4H28F@909932|Negativicutes 909932|Negativicutes L Psort location Cytoplasmic, score 8.96 - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_192492_1 243265.plu0543 1.91e-10 67.4 COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,1RPI8@1236|Gammaproteobacteria 1236|Gammaproteobacteria D recombinase XerD - - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_int_SAM_4,Phage_int_SAM_5,Phage_integrase k59_201125_1 113355.CM001775_gene1549 2.45e-25 120.0 COG3378@1|root,COG5545@1|root,COG3378@2|Bacteria,COG5545@2|Bacteria 2|Bacteria KL Phage plasmid primase P4 family - - - ko:K06919,ko:K09127 - - - - ko00000,ko02048 - - - AAA_25,D5_N,DUF3987,Pox_D5,PriCT_1,Prim-Pol k59_27365_1 1054460.SPPN_00145 7.38e-08 58.2 2CWXD@1|root,32T0J@2|Bacteria,1V83I@1239|Firmicutes,4HPQE@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k59_2566_4 475178.B2BTG9_9CAUD 1.05e-28 108.0 4QDUR@10239|Viruses,4QVMY@35237|dsDNA viruses no RNA stage,4QU8R@28883|Caudovirales,4QKNQ@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_2566_5 742733.HMPREF9469_05037 3.98e-14 70.1 2BD7A@1|root,326VE@2|Bacteria,1USRB@1239|Firmicutes,25ASG@186801|Clostridia,223BG@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_126878_1 46681.XP_001738227.1 4.52e-38 144.0 2CSEE@1|root,2RBK2@2759|Eukaryota,3X9MH@554915|Amoebozoa 554915|Amoebozoa G RNA helicase - - - - - - - - - - - - RNA_helicase k59_201127_1 43989.cce_3923 2.38e-55 187.0 COG3108@1|root,COG3179@1|root,COG3772@1|root,COG3108@2|Bacteria,COG3179@2|Bacteria,COG3772@2|Bacteria,1G5JF@1117|Cyanobacteria 1117|Cyanobacteria M Peptidoglycan-binding domain 1 protein - - - ko:K03791 - - - - ko00000 - GH19 - Glyco_hydro_19 k59_43796_1 76114.ebA7094 7.52e-08 60.8 COG1793@1|root,COG1793@2|Bacteria,1MUW3@1224|Proteobacteria,2VI3P@28216|Betaproteobacteria,2KUKX@206389|Rhodocyclales 206389|Rhodocyclales L DNA ligase dnaL - 6.5.1.1,6.5.1.6,6.5.1.7 ko:K10747 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00381,R00382,R10822,R10823 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - DNA_ligase_A_M,DNA_ligase_OB_2 k59_192573_2 1052684.PPM_2767 1.66e-11 70.1 COG4695@1|root,COG4695@2|Bacteria,1VX77@1239|Firmicutes 1239|Firmicutes S Phage portal protein - - - - - - - - - - - - Phage_portal k59_143677_1 1618248.A0A0C5IB82_9CIRC 7.27e-74 234.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_27498_1 1692249.A0A0K1RLN8_9CIRC 3.43e-22 98.2 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_226414_1 570952.ATVH01000011_gene340 6e-21 105.0 COG0503@1|root,COG1040@1|root,COG0503@2|Bacteria,COG1040@2|Bacteria,1QV41@1224|Proteobacteria 1224|Proteobacteria F acetyltransferase - - - - - - - - - - - - - k59_110195_2 1073754.G0ZND4_9VIRU 7.35e-110 333.0 4QGM3@10239|Viruses 10239|Viruses S oxidoreductase activity - - - - - - - - - - - - - k59_159604_3 439235.Dalk_1773 4.3e-06 48.1 COG2161@1|root,COG2161@2|Bacteria,1N07B@1224|Proteobacteria,42UIW@68525|delta/epsilon subdivisions,2WQU3@28221|Deltaproteobacteria,2MKSY@213118|Desulfobacterales 28221|Deltaproteobacteria D Antitoxin component of a toxin-antitoxin (TA) module - - - - - - - - - - - - PhdYeFM_antitox k59_159604_4 65093.PCC7418_0319 3.88e-27 100.0 2C16Q@1|root,330H3@2|Bacteria,1G90Z@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - HicB,RHH_1 k59_159604_5 715451.ambt_15655 1.64e-58 184.0 COG1569@1|root,COG1569@2|Bacteria,1N1T4@1224|Proteobacteria,1S7J5@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Toxin-antitoxin system, toxin component, PIN family - - - - - - - - - - - - PIN_3 k59_219818_5 1042209.HK44_002135 1.16e-78 241.0 COG1192@1|root,COG1192@2|Bacteria,1MWRE@1224|Proteobacteria,1RMZN@1236|Gammaproteobacteria 1236|Gammaproteobacteria D involved in chromosome partitioning - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31,MipZ k59_111410_1 1618247.A0A0C5IMK7_9CIRC 5.15e-05 49.7 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_78029_1 1165094.RINTHH_3920 4.5e-42 149.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_78029_3 105154.Q9MBU6_9VIRU 3.73e-218 621.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_78029_4 10855.H_SPV4 4.41e-06 52.4 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_11206_1 640513.Entas_3107 2.32e-21 91.7 COG0847@1|root,COG0847@2|Bacteria,1R9YS@1224|Proteobacteria,1S23K@1236|Gammaproteobacteria 1236|Gammaproteobacteria L 3' exoribonuclease, RNase T-like - - - ko:K10906 - - - - ko00000,ko01000,ko03400 - - - DUF5051,Exonuc_VIII k59_219836_1 1609634.A0A0C5AFV4_9VIRU 2.6e-94 292.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_153007_1 1379725.S5SYG4_9CIRC 8.08e-36 133.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_60869_3 1028800.RG540_CH13980 1.05e-52 182.0 COG5410@1|root,COG5410@2|Bacteria,1N0W2@1224|Proteobacteria,2U18J@28211|Alphaproteobacteria,4BHJS@82115|Rhizobiaceae 28211|Alphaproteobacteria K chromosome segregation - - - - - - - - - - - - Terminase_6C k59_119919_2 1123487.KB892865_gene1375 2.44e-43 150.0 28MVD@1|root,2ZB2Y@2|Bacteria,1R8NK@1224|Proteobacteria,2VPRP@28216|Betaproteobacteria,2KZJK@206389|Rhodocyclales 206389|Rhodocyclales S Protein of unknown function (DUF4043) - - - - - - - - - - - - DUF4043 k59_78164_3 10752.RPOLV_BPN4 9.49e-169 555.0 4QAXA@10239|Viruses,4QYJI@35237|dsDNA viruses no RNA stage,4QQ1A@28883|Caudovirales,4QNU7@10744|Podoviridae 10744|Podoviridae S metallopeptidase activity - - - - - - - - - - - - - k59_94306_1 1219035.NT2_13_00580 3.41e-33 130.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_229422_1 936573.HMPREF1147_2071 5.27e-08 60.5 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1TSMG@1239|Firmicutes,4H6SR@909932|Negativicutes 909932|Negativicutes S TIGRFAM Phage - - - - - - - - - - - - - k59_188305_1 716928.AJQT01000109_gene1217 3.68e-44 148.0 2FEUE@1|root,346TC@2|Bacteria,1MZPB@1224|Proteobacteria,2UC4Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_6499_2 1123279.ATUS01000005_gene3102 2.82e-19 90.9 2CJWY@1|root,31CWF@2|Bacteria,1RKEF@1224|Proteobacteria,1S75P@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_31055_1 1236504.HMPREF2132_11415 2.4e-36 134.0 COG0175@1|root,COG0175@2|Bacteria,4P029@976|Bacteroidetes,2FTVW@200643|Bacteroidia 976|Bacteroidetes EH Phosphoadenosine phosphosulfate reductase family - - 1.8.4.10,1.8.4.8 ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R02021 RC00007,RC02862 ko00000,ko00001,ko00002,ko01000 - - - PAPS_reduct k59_72048_1 1498011.A0A096XUT8_9CAUD 9.74e-63 208.0 4QAK6@10239|Viruses 10239|Viruses S N-acetylmuramoyl-L-alanine amidase activity - GO:0005575,GO:0019012 - - - - - - - - - - - k59_79991_1 1234888.K0A2J2_9VIRU 5.76e-85 269.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_47684_1 105154.Q9MBU6_9VIRU 3.26e-123 369.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_222569_1 984262.SGRA_3534 1.22e-18 90.9 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,1IPFU@117747|Sphingobacteriia 976|Bacteroidetes L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_104917_3 1209989.TepiRe1_0137 6.05e-06 47.8 COG1396@1|root,COG1396@2|Bacteria,1VGK2@1239|Firmicutes,25G5R@186801|Clostridia,42J7R@68295|Thermoanaerobacterales 186801|Clostridia K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 k59_96080_1 1385658.U5KPZ6_9VIRU 1.57e-70 229.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_182634_7 698761.RTCIAT899_CH11860 5.74e-10 68.9 COG3566@1|root,COG3566@2|Bacteria,1REIQ@1224|Proteobacteria,2U9XH@28211|Alphaproteobacteria,4BCNB@82115|Rhizobiaceae 28211|Alphaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2213) - - - ko:K09960 - - - - ko00000 - - - DUF2213 k59_157780_1 105154.Q9MBU6_9VIRU 3.81e-82 261.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_58270_2 1618259.A0A0C5I2B5_9CIRC 1.41e-75 239.0 4QE84@10239|Viruses,4QUKR@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_232470_1 1231190.NA8A_04863 8.89e-10 68.9 2FEZT@1|root,346YB@2|Bacteria,1RB9X@1224|Proteobacteria,2U5I3@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - Collagen k59_116387_3 1986029.Q9MBM8_9VIRU 2.37e-32 126.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_224073_3 1120963.KB894518_gene2794 3.5e-50 193.0 COG0749@1|root,COG0749@2|Bacteria,1MWX7@1224|Proteobacteria,1S0Q1@1236|Gammaproteobacteria 1236|Gammaproteobacteria L ORF located using Glimmer RBSfinder - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A,DNA_pol_A_exo1 k59_224073_4 658187.LDG_6143 4.31e-15 88.6 COG0467@1|root,COG1119@1|root,COG0467@2|Bacteria,COG1119@2|Bacteria 2|Bacteria P ATPase activity - - - ko:K03546,ko:K06919,ko:K07452,ko:K08482,ko:K09384,ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko01000,ko02042,ko02048,ko03400 - - - AAA_11,AAA_12,AAA_25,DUF4011 k59_224073_5 1157708.KB907450_gene5438 5.66e-49 194.0 28IJ1@1|root,2Z8K0@2|Bacteria,1R5PC@1224|Proteobacteria,2W0IK@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_224073_9 1304878.AUGD01000002_gene1833 6.43e-14 74.3 2DZ82@1|root,32V6V@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Tube k59_190930_1 1234888.K0A2J2_9VIRU 1.96e-63 212.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_257355_4 10872.VG301_BPPF3 5.42e-45 163.0 4QBME@10239|Viruses,4QUKP@29258|ssDNA viruses,4QP4G@10860|Inoviridae 10860|Inoviridae S Zonular occludens toxin (Zot) - - - - - - - - - - - - - k59_257355_10 232346.JHQL01000009_gene2032 1.77e-76 251.0 2D784@1|root,32TNH@2|Bacteria,1N098@1224|Proteobacteria,1SDM3@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_58372_6 1385658.U5KPZ6_9VIRU 1.29e-41 159.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_257443_1 1385658.U5KNR1_9VIRU 1.89e-28 116.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_257443_3 1986029.Q9MBM8_9VIRU 4.63e-39 143.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_124788_1 180503.Q8W6E3_9VIRU 2.14e-44 158.0 4QBCQ@10239|Viruses,4QUMB@29258|ssDNA viruses,4QP4S@10860|Inoviridae 10860|Inoviridae S DNA topoisomerase activity - - - - - - - - - - - - - k59_124788_2 672.VV93_v1c37930 6.15e-28 102.0 2BCPM@1|root,3269Y@2|Bacteria,1QMSP@1224|Proteobacteria,1TK2P@1236|Gammaproteobacteria,1Y1ZW@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k59_74992_1 1121441.AUCX01000032_gene3179 2.51e-87 330.0 COG0503@1|root,COG0827@1|root,COG0503@2|Bacteria,COG0827@2|Bacteria,1QZ6D@1224|Proteobacteria,42Z8W@68525|delta/epsilon subdivisions,2WU49@28221|Deltaproteobacteria,2MAY9@213115|Desulfovibrionales 28221|Deltaproteobacteria LMNU Methyltransferase small domain - - - - - - - - - - - - MTS k59_117546_1 1692244.A0A0K1RLR5_9CIRC 2.54e-23 100.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_67636_2 398525.KB900701_gene6148 1.11e-17 82.0 COG1783@1|root,COG1783@2|Bacteria,1R66A@1224|Proteobacteria,2TV42@28211|Alphaproteobacteria,3JXEI@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Phage terminase large subunit - - - ko:K06909 - - - - ko00000 - - - Terminase_3 k59_125863_1 1120792.JAFV01000001_gene1676 9.88e-23 100.0 COG3926@1|root,COG3926@2|Bacteria,1QV3R@1224|Proteobacteria,2UDA8@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Glycosyl hydrolase 108 - - - - - - - - - - - - Glyco_hydro_108,PG_binding_3 k59_233312_1 105154.Q9MBU3_9VIRU 1.01e-10 65.9 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_158619_1 1609634.A0A0C5AFV4_9VIRU 3.91e-21 91.7 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_158619_2 1609634.A0A0C5ANA6_9VIRU 7.98e-19 88.6 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_59374_1 1234888.K0A2J2_9VIRU 1.47e-72 234.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_142618_5 596152.DesU5LDRAFT_3296 1.42e-149 450.0 COG0305@1|root,COG0305@2|Bacteria,1PZ6S@1224|Proteobacteria,42YZ3@68525|delta/epsilon subdivisions,2WU0W@28221|Deltaproteobacteria,2MAW9@213115|Desulfovibrionales 28221|Deltaproteobacteria L Toprim-like - - - - - - - - - - - - DnaB_C,Toprim_2 k59_217358_1 334390.LAF_0464 1.68e-09 60.8 COG1061@1|root,COG1061@2|Bacteria,1TQ62@1239|Firmicutes,4HAJ1@91061|Bacilli,3F3YQ@33958|Lactobacillaceae 91061|Bacilli L Helicase C-terminal domain protein - - - - - - - - - - - - Helicase_C,ResIII k59_208537_1 1173023.KE650771_gene1990 2.39e-07 54.7 2DQKR@1|root,337HA@2|Bacteria,1G9HJ@1117|Cyanobacteria,1JJTT@1189|Stigonemataceae 1117|Cyanobacteria - - - - - - - - - - - - - - - k59_126027_3 1114179.I2FLQ9_9CAUD 2.38e-13 80.9 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_134269_1 155148.Q9AYZ7_BPHK6 6.02e-50 176.0 4QBD3@10239|Viruses,4QXFU@35237|dsDNA viruses no RNA stage,4QQ7Z@28883|Caudovirales,4QNJ0@10744|Podoviridae 10744|Podoviridae S P22 coat protein - gene protein 5 - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0008150,GO:0009987,GO:0016032,GO:0016043,GO:0019012,GO:0019028,GO:0019030,GO:0019058,GO:0019068,GO:0019069,GO:0019075,GO:0022607,GO:0039620,GO:0042802,GO:0042803,GO:0044085,GO:0044403,GO:0044419,GO:0044423,GO:0046729,GO:0046797,GO:0046983,GO:0051704,GO:0071840 - - - - - - - - - - - k59_1700_1 865938.Weevi_0272 5.87e-08 59.3 2DNQJ@1|root,32YKF@2|Bacteria,4PIY6@976|Bacteroidetes,1IAFC@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_241830_5 1457393.AZ09_10465 2.23e-47 160.0 COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,2TU8N@28211|Alphaproteobacteria,2JXEZ@204441|Rhodospirillales 204441|Rhodospirillales L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_144064_1 1123276.KB893279_gene2211 1.15e-15 79.0 2C9JF@1|root,32RPD@2|Bacteria 2|Bacteria S Erf family - - - - - - - - - - - - ERF k59_192866_1 460265.Mnod_6992 2.46e-128 379.0 COG0270@1|root,COG0270@2|Bacteria,1MV9H@1224|Proteobacteria,2TTZG@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family dcm - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase,HTH_3,HTH_31 k59_77417_1 1246459.KB898354_gene4735 9.79e-13 73.6 COG4675@1|root,COG4675@2|Bacteria,1N0FZ@1224|Proteobacteria,2UDXB@28211|Alphaproteobacteria,4BK5B@82115|Rhizobiaceae 28211|Alphaproteobacteria S Phage Tail Collar Domain - - - - - - - - - - - - Collar k59_234304_1 397291.C804_05817 3.36e-08 61.6 COG5518@1|root,COG5518@2|Bacteria,1TT5R@1239|Firmicutes,24XUM@186801|Clostridia 186801|Clostridia S Bacteriophage capsid portal protein - - - - - - - - - - - - - k59_209467_1 1379719.S5TMX6_9CIRC 6.93e-41 155.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_242951_1 1219035.NT2_13_00580 1.81e-26 111.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_152242_1 335284.Pcryo_0349 9.45e-43 159.0 COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,1RNA6@1236|Gammaproteobacteria,3NK8A@468|Moraxellaceae 1236|Gammaproteobacteria D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge k59_127555_2 1692253.A0A0K1RLM4_9CIRC 1.22e-07 53.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_160060_2 661478.OP10G_0157 7.25e-34 132.0 COG1783@1|root,COG1783@2|Bacteria 2|Bacteria S DNA packaging - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_6 k59_35818_1 1161401.ASJA01000008_gene1655 8.35e-64 214.0 COG3567@1|root,COG3567@2|Bacteria,1QNPU@1224|Proteobacteria,2U19C@28211|Alphaproteobacteria 28211|Alphaproteobacteria S TIGRFAM phage-associated protein, HI1409 family - - - ko:K09961 - - - - ko00000 - - - DUF1073 k59_209539_1 1588764.A0A0E3GD36_9VIRU 2e-57 186.0 4QB6C@10239|Viruses 10239|Viruses L Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_209539_2 1588764.A0A0E3GD36_9VIRU 3.75e-110 324.0 4QB6C@10239|Viruses 10239|Viruses L Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_209539_3 1634485.A0A0E3M076_9VIRU 1.32e-162 461.0 4QHM9@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_260121_3 1121098.HMPREF1534_03916 9.16e-15 71.2 28P3F@1|root,2ZBZ4@2|Bacteria,4NMPC@976|Bacteroidetes,2FSJ3@200643|Bacteroidia,4AR09@815|Bacteroidaceae 976|Bacteroidetes - - - - - - - - - - - - - - - k59_136807_4 488538.SAR116_0374 1.61e-42 157.0 2EGM1@1|root,33AD7@2|Bacteria,1NKQP@1224|Proteobacteria,2UKNH@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_128953_1 1618237.A0A0C5IMG6_9CIRC 4.71e-125 368.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_128953_2 1676988.A0A0H4FV52_9CIRC 6.08e-55 191.0 4QGVY@10239|Viruses,4QUKN@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_61518_1 795797.C497_05662 3.44e-18 89.0 COG5283@1|root,arCOG11109@2157|Archaea,2Y67M@28890|Euryarchaeota,23YYB@183963|Halobacteria 183963|Halobacteria S Phage tail tape measure protein, TP901 family - - - - - - - - - - - - PhageMin_Tail k59_70420_1 665956.HMPREF1032_00647 6.07e-45 165.0 2EWZQ@1|root,33QB0@2|Bacteria,1V0T1@1239|Firmicutes,249Z2@186801|Clostridia,3WNBH@541000|Ruminococcaceae 186801|Clostridia S DNA polymerase type-B family - - - - - - - - - - - - - k59_261422_1 1232443.BAIA02000078_gene46 1.25e-14 82.4 COG2887@1|root,COG2887@2|Bacteria,1TPIC@1239|Firmicutes,247TB@186801|Clostridia 186801|Clostridia L Psort location Cytoplasmic, score - - - - - - - - - - - - DUF2800 k59_120591_2 1165094.RINTHH_3920 2.45e-67 219.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_153750_2 742742.HMPREF9452_00380 2.28e-26 114.0 COG3948@1|root,COG3948@2|Bacteria,2HVQD@201174|Actinobacteria,4CX9N@84998|Coriobacteriia 84998|Coriobacteriia S Baseplate J-like protein - - - - - - - - - - - - Baseplate_J k59_161451_6 2003327.CAPSD_BPCHP 2.96e-37 144.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_78796_1 318586.Pden_3765 2.9e-31 113.0 2D1MV@1|root,32TAZ@2|Bacteria,1N45A@1224|Proteobacteria,2UEJT@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Phage protein (N4 Gp49/phage Sf6 gene 66) family - - - - - - - - - - - - Phage_gp49_66 k59_78796_2 1217715.F994_02778 1.23e-19 87.0 2EPAR@1|root,33GXH@2|Bacteria,1N7YQ@1224|Proteobacteria,1STFM@1236|Gammaproteobacteria,3NJS2@468|Moraxellaceae 1236|Gammaproteobacteria S RyR domain - - - - - - - - - - - - RyR k59_178260_1 743966.MYB_00585 9.93e-09 59.3 COG0692@1|root,COG0692@2|Bacteria,3WTJA@544448|Tenericutes 544448|Tenericutes L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine ung - 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k59_178260_2 1313421.JHBV01000049_gene74 6.87e-52 187.0 COG3864@1|root,COG3864@2|Bacteria,4NZN2@976|Bacteroidetes 976|Bacteroidetes S VWA-like domain (DUF2201) - - - - - - - - - - - - DUF2201,DUF2201_N k59_94897_1 1123258.AQXZ01000019_gene3111 1.09e-08 62.4 COG0270@1|root,COG0270@2|Bacteria,2GJR6@201174|Actinobacteria,4G3PI@85025|Nocardiaceae 201174|Actinobacteria L C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_172213_2 1692249.A0A0K1RLN8_9CIRC 4.51e-21 91.3 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_47914_2 1279038.KB907337_gene681 1.67e-06 48.9 28N1N@1|root,2ZB7Q@2|Bacteria,1R86T@1224|Proteobacteria,2U0A6@28211|Alphaproteobacteria,2JRMI@204441|Rhodospirillales 204441|Rhodospirillales H Sulfotransferase domain - - - - - - - - - - - - Sulfotransfer_1 k59_155553_1 279383.Q5DN81_9CAUD 1.49e-39 145.0 4QBA2@10239|Viruses,4QV98@35237|dsDNA viruses no RNA stage,4QPPI@28883|Caudovirales,4QM0B@10699|Siphoviridae 10699|Siphoviridae S Thymidylate synthase - GO:0003674,GO:0003824,GO:0004799,GO:0008150,GO:0008152,GO:0008168,GO:0016740,GO:0016741,GO:0032259,GO:0042083 - - - - - - - - - - - k59_105131_1 1042209.HK44_020560 8.93e-52 180.0 2CYA9@1|root,32T3V@2|Bacteria,1RGRN@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_179941_1 485916.Dtox_3709 9.37e-44 162.0 2DSX2@1|root,33HSD@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_236998_2 1417599.U6C7Z1_9CAUD 1.63e-75 250.0 4QD9Y@10239|Viruses,4QUXQ@35237|dsDNA viruses no RNA stage,4QTPE@28883|Caudovirales,4QNY4@10744|Podoviridae 10744|Podoviridae S Terminase-like family - - - - - - - - - - - - - k59_62940_1 202954.BBNK01000034_gene3794 2.71e-38 132.0 2A3Q7@1|root,30S7S@2|Bacteria,1NP2K@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_263026_2 1123228.AUIH01000006_gene2323 4.48e-40 139.0 COG2131@1|root,COG2131@2|Bacteria,1PNTJ@1224|Proteobacteria,1THD6@1236|Gammaproteobacteria,1XQDF@135619|Oceanospirillales 135619|Oceanospirillales F MafB19-like deaminase - - - - - - - - - - - - dCMP_cyt_deam_1 k59_222823_2 1609634.A0A0C5AFT2_9VIRU 2.52e-12 70.9 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_229925_2 1234888.K0A2R8_9VIRU 5.46e-18 85.5 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_196003_1 391612.CY0110_01065 1.49e-65 206.0 COG1192@1|root,COG1192@2|Bacteria,1G1EV@1117|Cyanobacteria,3KJGU@43988|Cyanothece 1117|Cyanobacteria D Cobyrinic acid ac-diamide synthase - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31,CbiA k59_223022_1 76869.PputGB1_1760 1.52e-54 192.0 28IJ1@1|root,2Z8K0@2|Bacteria,1R5PC@1224|Proteobacteria,1S1ER@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_131031_1 1283078.M1I879_9CAUD 0.000206 48.9 4QASG@10239|Viruses,4QZZU@35237|dsDNA viruses no RNA stage,4QT37@28883|Caudovirales,4QNXD@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_31507_1 331113.SNE_A18980 1.29e-06 57.0 COG2604@1|root,COG2604@2|Bacteria,2JFK8@204428|Chlamydiae 204428|Chlamydiae S Protein of unknown function DUF115 - - - - - - - - - - - - MAF_flag10 k59_180092_1 1094755.MCO_01092 1.96e-08 61.2 2CC8M@1|root,308VJ@2|Bacteria,1R789@1224|Proteobacteria,2U2NB@28211|Alphaproteobacteria,48TVI@772|Bartonellaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_72467_1 521000.PROVRETT_06010 5.56e-48 168.0 28J9D@1|root,2Z94E@2|Bacteria,1QE0C@1224|Proteobacteria,1RZ22@1236|Gammaproteobacteria 1236|Gammaproteobacteria S P22 coat protein - gene protein 5 - - - - - - - - - - - - P22_CoatProtein k59_72467_3 1121921.KB898706_gene3040 5.86e-67 238.0 28JKJ@1|root,2Z9DD@2|Bacteria,1MUN2@1224|Proteobacteria,1RQIP@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage P22-like portal protein - - - - - - - - - - - - P22_portal k59_98001_1 360107.CHAB381_0280 8.6e-39 161.0 COG5281@1|root,COG5281@2|Bacteria,1MX2R@1224|Proteobacteria,42THQ@68525|delta/epsilon subdivisions,2YRAB@29547|Epsilonproteobacteria 68525|delta/epsilon subdivisions S tape measure protein - - - - - - - - - - - - - k59_98001_12 582744.Msip34_1630 7.65e-15 88.6 COG2369@1|root,COG2369@2|Bacteria,1PUNX@1224|Proteobacteria,2VM1I@28216|Betaproteobacteria 28216|Betaproteobacteria S Phage Mu protein F like protein - - - - - - - - - - - - Phage_Mu_F k59_57827_2 1609634.A0A0C5ANA6_9VIRU 1.74e-20 92.8 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_57827_4 1609634.A0A0C5AFT2_9VIRU 3.68e-138 401.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_57827_6 1609634.A0A0C5AFV4_9VIRU 1.27e-148 437.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_57833_1 1493510.A0A0E3ICA9_9CAUD 1.21e-09 65.9 4QB69@10239|Viruses,4QSF0@28883|Caudovirales,4QJ3A@10662|Myoviridae 10662|Myoviridae S peptidase activity - - - - - - - - - - - - - k59_40384_1 979535.F1D037_9CAUD 1.2e-17 87.8 4QASG@10239|Viruses,4QZZU@35237|dsDNA viruses no RNA stage,4QT37@28883|Caudovirales,4QNXD@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_165158_1 1007103.AFHW01000034_gene2067 2.86e-13 83.6 COG3941@1|root,COG3941@2|Bacteria,1V33U@1239|Firmicutes,4HMR7@91061|Bacilli,2711P@186822|Paenibacillaceae 91061|Bacilli S tape measure - - - - - - - - - - - - - k59_57839_1 644076.SCH4B_3121 3.07e-11 63.9 2C0AZ@1|root,33W05@2|Bacteria,1NVUT@1224|Proteobacteria,2USJ8@28211|Alphaproteobacteria,4NDNA@97050|Ruegeria 28211|Alphaproteobacteria S Protein of unknown function (DUF3168) - - - - - - - - - - - - DUF3168 k59_239018_1 1541960.KQ78_01196 1.43e-10 70.5 28MKK@1|root,2ZAWR@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - RNA_helicase,Viral_Rep k59_165342_2 1472912.A0A023NGD1_9CAUD 1.06e-53 194.0 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales 28883|Caudovirales S DnaB-like helicase C terminal domain - - - - - - - - - - - - - k59_256108_1 1477404.A0A023NHC3_9CAUD 5.6e-26 103.0 4QAR6@10239|Viruses,4QUTK@35237|dsDNA viruses no RNA stage,4QPS2@28883|Caudovirales,4QNRU@10744|Podoviridae 10744|Podoviridae S dUTPase - - - - - - - - - - - - - k59_231948_1 1122176.KB903531_gene2762 3.3e-08 65.5 COG1572@1|root,COG4447@1|root,COG1572@2|Bacteria,COG4447@2|Bacteria 2|Bacteria S cellulose binding - - 3.2.1.51 ko:K15923 ko00511,map00511 - - - ko00000,ko00001,ko01000 - GH95 - Laminin_G_3,TM_helix k59_124645_1 1609634.A0A0C5ANA6_9VIRU 6.69e-08 57.4 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_157775_1 1420600.W5RNT1_9CIRC 5.4e-35 132.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_232463_1 1121935.AQXX01000130_gene2449 2.66e-109 324.0 COG3723@1|root,COG3723@2|Bacteria,1R6DB@1224|Proteobacteria,1RZZ3@1236|Gammaproteobacteria 1236|Gammaproteobacteria L COG3723 Recombinational DNA repair protein (RecE pathway) recT GO:0000724,GO:0000725,GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0018130,GO:0019438,GO:0032392,GO:0032508,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043150,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071704,GO:0071840,GO:0071897,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - ko:K07455 - - - - ko00000,ko03400 - - - RecT k59_285_48 1229755.K7R2F4_9CAUD 4.7e-12 78.2 4QC5Z@10239|Viruses,4QUNP@35237|dsDNA viruses no RNA stage,4QPGX@28883|Caudovirales,4QKMB@10699|Siphoviridae 10699|Siphoviridae S Phage Mu protein F like protein - GO:0005575,GO:0019012,GO:0019028,GO:0044423,GO:0046729 - - - - - - - - - - - k59_285_59 360107.CHAB381_0280 2.76e-39 164.0 COG5281@1|root,COG5281@2|Bacteria,1MX2R@1224|Proteobacteria,42THQ@68525|delta/epsilon subdivisions,2YRAB@29547|Epsilonproteobacteria 68525|delta/epsilon subdivisions S tape measure protein - - - - - - - - - - - - - k59_285_62 1121921.KB898707_gene986 2.75e-05 57.4 COG4733@1|root,COG4733@2|Bacteria,1NCQ4@1224|Proteobacteria,1SEXE@1236|Gammaproteobacteria 1236|Gammaproteobacteria S cellulase activity - - - - - - - - - - - - DUF1983,DUF3672 k59_257424_2 1116472.MGMO_205c00030 7.36e-105 324.0 28IN7@1|root,2Z8NM@2|Bacteria,1NRFQ@1224|Proteobacteria,1SKG7@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Capsid protein (F protein) - - - - - - - - - - - - Phage_F k59_232534_1 142661.REP_CACV 7.33e-41 154.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_225169_1 1692249.A0A0K1RLN8_9CIRC 5.46e-49 166.0 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_183576_1 1165096.ARWF01000001_gene594 2.77e-18 85.9 COG2268@1|root,COG2268@2|Bacteria,1P39U@1224|Proteobacteria,2VMEW@28216|Betaproteobacteria 28216|Betaproteobacteria S prohibitin homologues - - - - - - - - - - - - Band_7 k59_134000_1 292563.Cyast_2794 7.15e-67 214.0 COG0675@1|root,COG0675@2|Bacteria,1G10J@1117|Cyanobacteria 1117|Cyanobacteria L COG0675 Transposase and inactivated derivatives - - - ko:K07496 - - - - ko00000 - - - OrfB_IS605,OrfB_Zn_ribbon k59_67500_2 1220714.L7TRY6_9CAUD 2.05e-08 57.8 4QDKA@10239|Viruses,4QWTD@35237|dsDNA viruses no RNA stage,4QQ19@28883|Caudovirales,4QIB9@10662|Myoviridae 10662|Myoviridae S nuclease activity - - - - - - - - - - - - - k59_249897_1 1609634.A0A0C5AK24_9VIRU 6.46e-14 67.8 4QCC5@10239|Viruses,4QUKW@29258|ssDNA viruses,4QP4C@10841|Microviridae 10841|Microviridae S viral process - - - - - - - - - - - - - k59_92467_1 1609634.A0A0C5AFV4_9VIRU 5.24e-73 238.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_92467_2 145579.C_BPPHM 2.71e-10 60.1 4QCC5@10239|Viruses,4QUKW@29258|ssDNA viruses,4QP4C@10841|Microviridae 10841|Microviridae S viral process - - - - - - - - - - - - - k59_150598_1 105154.Q9MBU0_9VIRU 1.01e-25 107.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_150598_6 1609634.A0A0C5AFV4_9VIRU 3.92e-82 271.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_108960_1 691965.D4P7D6_9CAUD 7.13e-91 298.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_108960_4 742733.HMPREF9469_05026 3.75e-58 190.0 28NM4@1|root,2ZBMQ@2|Bacteria,1V1QD@1239|Firmicutes,24G1B@186801|Clostridia,221N8@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_108960_6 428125.CLOLEP_01417 2.09e-30 116.0 2CGG9@1|root,2ZVSJ@2|Bacteria,1V633@1239|Firmicutes,24HD0@186801|Clostridia,3WMXK@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_108960_7 742740.HMPREF9474_02263 1.62e-25 100.0 2ARVA@1|root,31H70@2|Bacteria,1V7JT@1239|Firmicutes,24JPE@186801|Clostridia,222RD@1506553|Lachnoclostridium 186801|Clostridia S Bacteriophage HK97-gp10, putative tail-component - - - - - - - - - - - - HK97-gp10_like k59_108960_8 742733.HMPREF9469_05020 2.02e-122 419.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia,221IX@1506553|Lachnoclostridium 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_84012_1 713586.KB900537_gene3099 9.46e-32 126.0 2DCM2@1|root,32TZV@2|Bacteria,1NAGE@1224|Proteobacteria,1SMRS@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_225176_2 1288298.rosmuc_03782 1.09e-35 125.0 COG1396@1|root,COG1396@2|Bacteria,1N6V6@1224|Proteobacteria,2UGCV@28211|Alphaproteobacteria 28211|Alphaproteobacteria K transcriptional regulator - - - - - - - - - - - - HTH_19,HTH_3,HTH_31 k59_184757_1 186617.M9M8L2_9VIRU 3.8e-91 284.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_18690_4 942016.E9NIF9_9CAUD 2.18e-10 64.3 4QB3X@10239|Viruses,4QWKP@35237|dsDNA viruses no RNA stage,4QPEE@28883|Caudovirales,4QNCI@10744|Podoviridae 10744|Podoviridae S VWA-like domain (DUF2201) - - - - - - - - - - - - - k59_10516_1 428125.CLOLEP_01422 2.05e-132 435.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia,3WN92@541000|Ruminococcaceae 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_27759_5 1234888.K0A2J2_9VIRU 5.98e-21 93.6 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_152136_1 1429767.W6AQV5_9CAUD 0.0 903.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_152136_3 1429767.W6ARJ8_9CAUD 2.56e-113 346.0 4QBY0@10239|Viruses,4QW35@35237|dsDNA viruses no RNA stage,4QQ4Q@28883|Caudovirales,4QNNN@10744|Podoviridae 10744|Podoviridae S UvrD-like helicase C-terminal domain - - - - - - - - - - - - - k59_152136_5 391589.RGAI101_1984 0.000558 43.9 COG2916@1|root,COG2916@2|Bacteria,1N801@1224|Proteobacteria,2UF4Y@28211|Alphaproteobacteria,2P3RU@2433|Roseobacter 28211|Alphaproteobacteria L COG2916 DNA-binding protein H-NS - - - ko:K03746 - - - - ko00000,ko03036,ko03400 - - - Histone_HNS k59_152136_6 696748.ASU2_02560 3.55e-36 132.0 COG4696@1|root,COG4696@2|Bacteria,1Q356@1224|Proteobacteria,1TFWD@1236|Gammaproteobacteria,1YACQ@135625|Pasteurellales 135625|Pasteurellales S Protein conserved in bacteria - - - - - - - - - - - - - k59_250936_6 1460635.JCM19038_3780 4.07e-11 65.9 COG3409@1|root,COG3409@2|Bacteria 2|Bacteria M Peptidoglycan-binding domain 1 protein - - - - - - - - - - - - Amidase_2,PG_binding_1 k59_52563_1 1385658.U5KPZ6_9VIRU 7.52e-71 235.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_226508_2 1122179.KB890417_gene3273 6.41e-94 298.0 COG2425@1|root,COG2425@2|Bacteria 2|Bacteria S positive regulation of ATPase activity rsr - - ko:K11089 ko05322,map05322 - - - ko00000,ko00001 - - - TROVE,VWA_CoxE k59_176539_1 1379714.S5TND6_9CIRC 1.29e-60 195.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_201565_1 648757.Rvan_3517 3.52e-15 80.9 COG3203@1|root,COG3203@2|Bacteria,1N25J@1224|Proteobacteria,2TYC2@28211|Alphaproteobacteria,3N9J4@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - - - - - - - - - - Porin_4 k59_145518_1 438753.AZC_3607 4.8e-35 134.0 COG5108@1|root,COG5108@2|Bacteria,1PIWB@1224|Proteobacteria,2U1JR@28211|Alphaproteobacteria 28211|Alphaproteobacteria K DNA-dependent RNA polymerase - - - - - - - - - - - - RNA_pol,RPOL_N k59_186234_1 105154.Q9MBU6_9VIRU 1.54e-220 628.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_186234_3 1385658.U5KNR1_9VIRU 1.14e-81 257.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_11726_1 926551.KB900735_gene1489 7.46e-23 94.4 COG4696@1|root,COG4696@2|Bacteria,4NNW2@976|Bacteroidetes,1I23U@117743|Flavobacteriia,1ET44@1016|Capnocytophaga 976|Bacteroidetes S Phosphoribosyl-ATP pyrophosphohydrolase - - - - - - - - - - - - PRA-PH k59_19787_1 1692249.A0A0K1RL40_9CIRC 3.07e-41 147.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_19787_3 759938.F5BSB4_9CIRC 1.21e-05 49.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_145519_1 655097.C8ZKD4_9CAUD 0.000878 47.0 4QBY0@10239|Viruses,4QW35@35237|dsDNA viruses no RNA stage,4QQ4Q@28883|Caudovirales,4QNNN@10744|Podoviridae 10744|Podoviridae S UvrD-like helicase C-terminal domain - - - - - - - - - - - - - k59_94608_1 675806.VII_003800 1.23e-63 197.0 COG3108@1|root,COG3108@2|Bacteria,1RICX@1224|Proteobacteria,1S5B3@1236|Gammaproteobacteria 1236|Gammaproteobacteria S D-alanyl-D-alanine carboxypeptidase - - - - - - - - - - - - Peptidase_M15_4 k59_170230_3 1609634.A0A0C5AFV4_9VIRU 1.3e-83 266.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_29207_2 445692.E3SP51_9CAUD 2.17e-26 107.0 4QBMX@10239|Viruses,4QV9I@35237|dsDNA viruses no RNA stage,4QQGF@28883|Caudovirales,4QNC1@10744|Podoviridae 10744|Podoviridae S Pfam:Tube - GO:0005575,GO:0019012 - - - - - - - - - - - k59_145636_1 931627.MycrhDRAFT_1176 1.8e-20 90.1 COG3740@1|root,COG3740@2|Bacteria,2II2M@201174|Actinobacteria,239DQ@1762|Mycobacteriaceae 201174|Actinobacteria S Phage prohead protease, HK97 family - - - - - - - - - - - - - k59_129003_1 1385511.N783_02635 1.7e-15 83.6 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,4H9S7@91061|Bacilli,2Y9TG@289201|Pontibacillus 91061|Bacilli L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A k59_186363_1 391596.PBAL39_25275 9.5e-05 54.7 COG0018@1|root,COG3210@1|root,COG3266@1|root,COG4409@1|root,COG0018@2|Bacteria,COG3210@2|Bacteria,COG3266@2|Bacteria,COG4409@2|Bacteria,4NQ80@976|Bacteroidetes 976|Bacteroidetes G Collagen triple helix repeat (20 copies) - - - - - - - - - - - - Collagen k59_61364_2 226185.EF_2318 1.93e-10 63.5 COG0739@1|root,COG0791@1|root,COG0739@2|Bacteria,COG0791@2|Bacteria,1TP24@1239|Firmicutes,4I29P@91061|Bacilli,4B53D@81852|Enterococcaceae 91061|Bacilli M NlpC/P60 family - - - - - - - - - - - - NLPC_P60 k59_61364_3 1031288.AXAA01000003_gene1627 2.97e-06 49.7 2EUFA@1|root,33MXK@2|Bacteria,1VQFP@1239|Firmicutes,24S0X@186801|Clostridia,36N6B@31979|Clostridiaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_220663_1 105154.Q9MBU6_9VIRU 1.86e-69 228.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_70266_1 1357732.A0A059PYD9_9CAUD 1.47e-14 80.9 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales,4QNBW@10744|Podoviridae 10744|Podoviridae S DNA helicase activity - - - - - - - - - - - - - k59_194113_1 992406.RIA_2082 5.13e-13 76.6 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,1HXMT@117743|Flavobacteriia 976|Bacteroidetes L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_170244_1 243232.MJ_1445 3.45e-18 84.0 COG4186@1|root,arCOG01154@2157|Archaea,2XYK6@28890|Euryarchaeota 28890|Euryarchaeota S PFAM Metallophosphoesterase - - - - - - - - - - - - 2_5_RNA_ligase2,Metallophos,Metallophos_2 k59_21007_8 1454202.PPBDW_140041___1 6.39e-12 72.0 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RMIR@1236|Gammaproteobacteria,1XTK9@135623|Vibrionales 135623|Vibrionales M COG0739 Membrane proteins related to metalloendopeptidases - - - - - - - - - - - - Peptidase_M23 k59_138413_1 1609634.A0A0C5AFT2_9VIRU 3.58e-28 114.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_37942_2 1283283.ATXA01000001_gene518 8.16e-12 69.3 COG4122@1|root,COG4122@2|Bacteria,2IP3G@201174|Actinobacteria 201174|Actinobacteria S Methyltransferase domain - - - - - - - - - - - - Methyltransf_24 k59_187996_1 1234888.K0A2J2_9VIRU 1.47e-159 467.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_62501_1 645099.MREP_BBTVA 4.46e-30 119.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_122009_1 1176422.I6R1G5_9CAUD 1.14e-05 48.5 4QDBD@10239|Viruses,4QZWQ@35237|dsDNA viruses no RNA stage,4QR4N@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_229367_2 935836.JAEL01000005_gene2721 6.27e-13 66.2 COG1591@1|root,COG1591@2|Bacteria,1V9FG@1239|Firmicutes,4HSSG@91061|Bacilli 91061|Bacilli L VRR_NUC - - - - - - - - - - - - - k59_79765_2 1795988.A0A140CTK3_9VIRU 3.53e-05 48.5 4QB6C@10239|Viruses 10239|Viruses L Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_55360_6 196627.cg1843 2.65e-05 55.5 COG0553@1|root,COG0553@2|Bacteria,2GISC@201174|Actinobacteria,22K8F@1653|Corynebacteriaceae 201174|Actinobacteria L Superfamily II DNA RNA helicases, SNF2 family - - - - - - - - - - - - HHH_5,Helicase_C,SNF2_N k59_222259_10 202954.BBNK01000034_gene3794 1.86e-46 153.0 2A3Q7@1|root,30S7S@2|Bacteria,1NP2K@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_47419_1 10760.CAPSB_BPT7 4.69e-15 75.5 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QNI0@10744|Podoviridae 10744|Podoviridae S viral capsid - GO:0003674,GO:0005488,GO:0005515,GO:0042802 - - - - - - - - - - - k59_122013_1 349521.HCH_02886 4.31e-41 141.0 COG3023@1|root,COG3023@2|Bacteria,1N032@1224|Proteobacteria,1SFIP@1236|Gammaproteobacteria,1XPM6@135619|Oceanospirillales 135619|Oceanospirillales V N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - Amidase_2 k59_156438_1 1692249.A0A0K1RL40_9CIRC 2.1e-24 103.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_223783_2 1676184.A0A186YBN5_9CIRC 2.61e-35 137.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_131613_2 1458858.A0A088C3E0_9CAUD 1.76e-23 96.3 4QHDQ@10239|Viruses,4R0J3@35237|dsDNA viruses no RNA stage,4QSUU@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_39245_2 366394.Smed_1622 3.28e-18 85.5 COG0582@1|root,COG0582@2|Bacteria,1NWGS@1224|Proteobacteria,2TQWR@28211|Alphaproteobacteria,4B95V@82115|Rhizobiaceae 28211|Alphaproteobacteria L Belongs to the 'phage' integrase family rci - - - - - - - - - - - Phage_integrase k59_105990_1 1197906.CAJQ02000016_gene198 1.15e-16 90.1 28JTG@1|root,2Z9IR@2|Bacteria,1R0GC@1224|Proteobacteria,2TURR@28211|Alphaproteobacteria,3JUCC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF2793) - - - - - - - - - - - - DUF2793 k59_22513_1 1499968.TCA2_4474 2.58e-11 67.0 COG0758@1|root,COG0758@2|Bacteria,1VNFT@1239|Firmicutes,4HZZP@91061|Bacilli 91061|Bacilli LU Protein of unknown function (DUF2493) - - - - - - - - - - - - DUF2493 k59_139995_1 1540097.A0A0A0YR01_9CAUD 8.24e-26 111.0 4QE55@10239|Viruses,4QSGR@28883|Caudovirales,4QNIB@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_63737_1 107636.JQNK01000009_gene1991 6.03e-65 223.0 COG0553@1|root,COG0553@2|Bacteria,1NII1@1224|Proteobacteria 1224|Proteobacteria L SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,SNF2_N k59_156515_1 1247024.JRLH01000018_gene546 2.51e-30 124.0 2CDPS@1|root,2ZBQT@2|Bacteria,1RB59@1224|Proteobacteria,1S2U0@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage replication protein CRI g2p - - - - - - - - - - - Phage_CRI,Phage_X k59_140093_1 1327974.S0A0U7_9CAUD 2.12e-44 164.0 4QCHV@10239|Viruses,4QUW9@35237|dsDNA viruses no RNA stage,4QQEZ@28883|Caudovirales,4QMEA@10699|Siphoviridae 10699|Siphoviridae S Virulence-associated protein E - - - - - - - - - - - - - k59_15767_1 462590.A9J4Z1_BPPYU 2.04e-16 85.5 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_256142_2 1379715.S5TMW6_9CIRC 5.17e-52 178.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_82473_1 1556290.A0A0A0RQE6_9CAUD 6.37e-36 130.0 4QAUS@10239|Viruses,4QQ2S@28883|Caudovirales,4QKRA@10699|Siphoviridae 10699|Siphoviridae S flavin adenine dinucleotide binding - - - - - - - - - - - - - k59_82473_2 410359.Pcal_1351 4.66e-12 67.8 arCOG05626@1|root,arCOG05626@2157|Archaea 2157|Archaea - - - - - - - - - - - - - - - k59_98269_4 1054461.G0XNV0_9CAUD 9.97e-157 511.0 4QAXA@10239|Viruses,4QYJI@35237|dsDNA viruses no RNA stage,4QQ1A@28883|Caudovirales,4QNU7@10744|Podoviridae 10744|Podoviridae S metallopeptidase activity - - - - - - - - - - - - - k59_214517_4 1493511.A0A0E3HIK0_9CAUD 5.16e-05 49.3 4QAK6@10239|Viruses 10239|Viruses S N-acetylmuramoyl-L-alanine amidase activity - - - - - - - - - - - - - k59_198266_2 1123058.KB894283_gene1542 8.1e-06 53.9 COG3064@1|root,COG5295@1|root,COG3064@2|Bacteria,COG5295@2|Bacteria 2|Bacteria UW Hep Hag repeat protein tek - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - HemolysinCabind,Hint_2,Peptidase_S74 k59_82484_2 1609634.A0A0C5AFT2_9VIRU 1.7e-15 79.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_256156_1 1261131.lam_649 1.68e-15 77.4 COG0553@1|root,COG0553@2|Bacteria,1PXS8@1224|Proteobacteria,2UAZ5@28211|Alphaproteobacteria,4BED4@82115|Rhizobiaceae 28211|Alphaproteobacteria KL COG0553 Superfamily II DNA RNA helicases, SNF2 family - - - - - - - - - - - - SNF2_N k59_239374_1 1121033.AUCF01000009_gene1201 1.03e-41 144.0 COG1442@1|root,COG1442@2|Bacteria,1QH4S@1224|Proteobacteria,2U2NZ@28211|Alphaproteobacteria,2JTII@204441|Rhodospirillales 204441|Rhodospirillales M glycosyl transferase family 8 - - - - - - - - - - - - - k59_15771_1 1029823.AFIE01000007_gene1892 3.1e-10 58.5 2DYV8@1|root,32V63@2|Bacteria,1QNWV@1224|Proteobacteria,1ST2X@1236|Gammaproteobacteria,3NNP1@468|Moraxellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_107022_2 1609634.A0A0C5AFV4_9VIRU 3.66e-81 258.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_98276_1 457398.HMPREF0326_03019 9.68e-83 260.0 COG0507@1|root,COG0507@2|Bacteria,1R1AT@1224|Proteobacteria,42UU6@68525|delta/epsilon subdivisions,2X85I@28221|Deltaproteobacteria,2MCJ2@213115|Desulfovibrionales 28221|Deltaproteobacteria L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD - - - - - - - - - - - - - k59_40673_1 1327977.S0A0N2_9CAUD 1.34e-118 370.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales 28883|Caudovirales S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_264945_4 526227.Mesil_1753 1.66e-07 60.1 2EP1Y@1|root,33GNT@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_65049_1 1986029.Q9MBM3_9VIRU 3.86e-39 142.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_182195_1 1556290.A0A0A0RM00_9CAUD 5.7e-56 193.0 4QAXQ@10239|Viruses,4QRFY@28883|Caudovirales,4QM52@10699|Siphoviridae 10699|Siphoviridae S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor - - - - - - - - - - - - - k59_256161_1 10761.Q716H0_BPSFV 7.84e-52 182.0 4QBD3@10239|Viruses,4QXFU@35237|dsDNA viruses no RNA stage,4QQ7Z@28883|Caudovirales,4QNJ0@10744|Podoviridae 10744|Podoviridae S P22 coat protein - gene protein 5 - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0008150,GO:0009987,GO:0016032,GO:0016043,GO:0019012,GO:0019028,GO:0019030,GO:0019058,GO:0019068,GO:0019069,GO:0019075,GO:0022607,GO:0039620,GO:0042802,GO:0042803,GO:0044085,GO:0044403,GO:0044419,GO:0044423,GO:0046729,GO:0046797,GO:0046983,GO:0051704,GO:0071840 - - - - - - - - - - - k59_74601_1 1197951.I6RT34_9CAUD 1.21e-146 432.0 4QGAG@10239|Viruses,4R0KB@35237|dsDNA viruses no RNA stage,4QUA4@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_74601_3 521000.PROVRETT_05530 3.64e-26 100.0 COG3179@1|root,COG3179@2|Bacteria,1RE8K@1224|Proteobacteria,1S4U8@1236|Gammaproteobacteria,3Z9BP@586|Providencia 1236|Gammaproteobacteria S D-alanyl-D-alanine carboxypeptidase - - - - - - - - - - - - Peptidase_M15_4 k59_74601_5 1485544.JQKP01000011_gene745 3.64e-18 82.8 2E645@1|root,330T3@2|Bacteria,1NEGX@1224|Proteobacteria,2VY99@28216|Betaproteobacteria 28216|Betaproteobacteria S Holin of 3TMs, for gene-transfer release - - - - - - - - - - - - GTA_holin_3TM k59_182375_4 563192.HMPREF0179_03420 2.07e-23 94.4 2EHVE@1|root,32QS6@2|Bacteria,1P3YB@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_141320_1 136084.Q9G0G7_9CAUD 8.26e-24 94.4 4QASP@10239|Viruses,4QVR8@35237|dsDNA viruses no RNA stage,4QR4Z@28883|Caudovirales,4QNQ0@10744|Podoviridae 10744|Podoviridae S deoxyribonuclease IV (phage-T4-induced) activity - - - - - - - - - - - - - k59_224196_1 945083.W0LM09_9CAUD 1.92e-76 241.0 4QAIJ@10239|Viruses,4QVZ9@35237|dsDNA viruses no RNA stage,4QPXI@28883|Caudovirales,4QM02@10699|Siphoviridae 10699|Siphoviridae S C-5 cytosine-specific DNA methylase - - - - - - - - - - - - - k59_25325_1 1370122.JHXQ01000018_gene69 7.62e-26 105.0 2EHNC@1|root,33BE4@2|Bacteria,1R1ZS@1224|Proteobacteria,2TZ7V@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_215991_4 856793.MICA_562 3.88e-57 202.0 28IAN@1|root,2Z8D8@2|Bacteria,1NJD6@1224|Proteobacteria,2U7YP@28211|Alphaproteobacteria,4BR2J@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S Domain of unknown function (DUF4055) - - - - - - - - - - - - DUF4055 k59_99851_1 1385658.U5KPZ6_9VIRU 5.83e-188 544.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_99851_5 1165094.RINTHH_3920 4.2e-64 211.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_108184_1 1282360.ABAC460_19840 5.7e-143 422.0 COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria 1224|Proteobacteria C SMART Elongator protein 3 MiaB NifB - - - - - - - - - - - - B12-binding,Radical_SAM k59_166144_1 2003327.CAPSD_BPCHP 9.55e-22 99.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_66656_3 1219035.NT2_13_00580 4.33e-157 457.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_66656_4 5786.XP_003287163.1 2.32e-25 100.0 2CU0K@1|root,2RIN8@2759|Eukaryota,3XIDH@554915|Amoebozoa 554915|Amoebozoa S Protein of unknown function (DUF2778) - - - - - - - - - - - - DUF2778 k59_33568_1 1177181.T9A_00229 4.33e-35 139.0 COG2946@1|root,COG2946@2|Bacteria,1RDKM@1224|Proteobacteria,1S7EJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Replication initiation factor - - - - - - - - - - - - Rep_trans k59_41846_1 1120998.AUFC01000030_gene2214 2.05e-13 72.0 2ECRE@1|root,336P5@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_249179_1 883096.HMPREF9699_01317 3.33e-54 185.0 28JJ1@1|root,2Z9C5@2|Bacteria,4NJEU@976|Bacteroidetes,1I0KB@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_25330_1 259536.Psyc_1513 1.39e-05 51.2 COG0457@1|root,COG0457@2|Bacteria,1N66D@1224|Proteobacteria,1SAX7@1236|Gammaproteobacteria,3NJWX@468|Moraxellaceae 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - k59_108238_1 196490.AUEZ01000004_gene3956 2.12e-48 160.0 2A4D4@1|root,30SYX@2|Bacteria,1PCIM@1224|Proteobacteria,2USSQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_207681_4 1234888.K0A2J2_9VIRU 5.97e-181 523.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_75111_1 620914.JH621310_gene55 3.05e-07 52.4 COG2273@1|root,COG5434@1|root,COG2273@2|Bacteria,COG5434@2|Bacteria 2|Bacteria M polygalacturonase activity - - - - - - - - - - - - Beta_helix,CBM_6,Glyco_hydro_16,Pectate_lyase_3,RicinB_lectin_2 k59_124912_1 1795988.A0A140CTK3_9VIRU 3.01e-13 73.6 4QB6C@10239|Viruses 10239|Viruses L Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_16951_1 1486472.A0A068F1U8_9CAUD 9.63e-66 213.0 4QATB@10239|Viruses,4QVUZ@35237|dsDNA viruses no RNA stage,4QPGA@28883|Caudovirales 28883|Caudovirales S Phosphoadenosine phosphosulfate reductase family - - - - - - - - - - - - - k59_16951_2 716928.AJQT01000079_gene1026 2.35e-05 45.1 COG0450@1|root,COG0450@2|Bacteria,1MX2B@1224|Proteobacteria,2TT09@28211|Alphaproteobacteria,4B7AE@82115|Rhizobiaceae 28211|Alphaproteobacteria O peroxidase tsaA GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0010035,GO:0010038,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0046686,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - - - - - - - - - - 1-cysPrx_C,AhpC-TSA k59_199449_3 314230.DSM3645_28792 0.000334 53.5 COG1357@1|root,COG1357@2|Bacteria,2J2VS@203682|Planctomycetes 203682|Planctomycetes S PFAM Pentapeptide repeats (8 copies) - - - - - - - - - - - - - k59_166213_1 877455.Metbo_2475 4.18e-20 102.0 COG3291@1|root,arCOG02516@1|root,arCOG09475@1|root,arCOG02508@2157|Archaea,arCOG02510@2157|Archaea,arCOG02516@2157|Archaea,arCOG09475@2157|Archaea,2Y7U0@28890|Euryarchaeota 28890|Euryarchaeota S Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - - - - - - - - - - PKD k59_149687_1 1384484.AEQU_1746 4.17e-36 136.0 COG1180@1|root,COG1180@2|Bacteria,2HSWV@201174|Actinobacteria,4CVGK@84998|Coriobacteriia 84998|Coriobacteriia C Elongator protein 3, MiaB family, Radical SAM - - 1.97.1.4 ko:K04069 - - R04710 - ko00000,ko01000 - - - Radical_SAM k59_149687_4 511.JT27_18510 1.17e-31 127.0 COG5518@1|root,COG5518@2|Bacteria,1MYGZ@1224|Proteobacteria 1224|Proteobacteria S Phage portal protein, PBSX family - - - - - - - - - - - - Phage_portal k59_142445_2 582899.Hden_1190 3.22e-13 69.3 COG1694@1|root,COG1694@2|Bacteria,1N3XF@1224|Proteobacteria,2UG4F@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Mazg nucleotide pyrophosphohydrolase - - - - - - - - - - - - - k59_117641_1 1692256.A0A0K1RL85_9CIRC 2.7e-59 195.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_117641_2 1692242.A0A0K1RKZ2_9CIRC 1.19e-46 165.0 4QFEW@10239|Viruses,4QUKZ@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_200302_2 1396141.BATP01000003_gene4864 1.69e-05 54.3 COG2273@1|root,COG3210@1|root,COG3533@1|root,COG3637@1|root,COG4733@1|root,COG5184@1|root,COG5295@1|root,COG2273@2|Bacteria,COG3210@2|Bacteria,COG3533@2|Bacteria,COG3637@2|Bacteria,COG4733@2|Bacteria,COG5184@2|Bacteria,COG5295@2|Bacteria,46Z9Q@74201|Verrucomicrobia,2IVEQ@203494|Verrucomicrobiae 2|Bacteria DEGMUZ Repeats in polycystic kidney disease 1 (PKD1) and other proteins oprH - 3.2.1.4,3.2.1.73 ko:K01179,ko:K01216,ko:K02014,ko:K07004,ko:K15125,ko:K16087,ko:K21449 ko00500,ko01100,ko05133,map00500,map01100,map05133 - R06200,R11307,R11308 - ko00000,ko00001,ko00536,ko01000,ko02000 1.B.14,1.B.14.2,1.B.40.2 GH5,GH9 - Glyco_hydro_16,HemolysinCabind,OMP_b-brl,fn3 k59_76107_2 186617.M9M8L2_9VIRU 0.000127 49.3 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_158686_1 391595.RLO149_c014800 1.78e-11 61.6 2EJIR@1|root,33D9N@2|Bacteria,1NHKK@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - DUF4376,Phage_tail_APC k59_191842_2 1379708.S5SYC3_9CIRC 7.15e-29 116.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_117646_5 1196322.A370_04528 8.5e-16 73.9 COG0742@1|root,COG0742@2|Bacteria,1UN8R@1239|Firmicutes,250IW@186801|Clostridia,36RQ5@31979|Clostridiaceae 186801|Clostridia L ribosomal rna small subunit methyltransferase - - - - - - - - - - - - - k59_233358_5 233412.HD_0501 2.12e-40 142.0 COG3023@1|root,COG3023@2|Bacteria,1RJ5G@1224|Proteobacteria,1SYPJ@1236|Gammaproteobacteria,1Y8A5@135625|Pasteurellales 135625|Pasteurellales V N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - Amidase_2 k59_233358_6 1300005.R9RGD4_9CAUD 9.42e-30 112.0 4QB2U@10239|Viruses,4QVJC@35237|dsDNA viruses no RNA stage,4QTMH@28883|Caudovirales 28883|Caudovirales S Pfam:GTA_holin_3TM - - - - - - - - - - - - - k59_233358_8 753085.F4YCV3_9CAUD 1.5e-58 201.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_9474_1 1234888.K0A2J2_9VIRU 2.47e-115 353.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_9474_6 1234888.K0A2J2_9VIRU 7.82e-15 73.9 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_184943_2 142661.REP_CACV 1.66e-14 79.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_144030_1 291603.REP7_FBNY1 2.91e-10 63.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_60332_1 145579.CAPSD_BPPHM 1.28e-52 182.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_60332_7 1385658.U5KPZ6_9VIRU 3.31e-142 421.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_168770_2 291607.MREP_SCSVF 5.77e-14 78.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_10570_1 691965.D4P7D6_9CAUD 3.6e-34 134.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_250974_4 1174529.WSI_05020 2.46e-13 76.6 290X3@1|root,2ZNIW@2|Bacteria,1P7TA@1224|Proteobacteria,2UXFQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_250974_6 1219035.NT2_13_00580 5.36e-33 132.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_110712_1 1692252.A0A0K1RL35_9CIRC 1.96e-62 206.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_93710_1 1041147.AUFB01000007_gene643 2.51e-23 105.0 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1NKZK@1224|Proteobacteria,2U0EG@28211|Alphaproteobacteria,4B9VS@82115|Rhizobiaceae 28211|Alphaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6C k59_234373_1 157783.LK03_14945 1.97e-09 60.1 COG0640@1|root,COG0640@2|Bacteria,1RGKD@1224|Proteobacteria,1S53G@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Helix-turn-helix domain - - - - - - - - - - - - HTH_36 k59_234373_2 1408428.JNJP01000003_gene3493 9.33e-64 204.0 COG0270@1|root,COG0270@2|Bacteria 2|Bacteria L DNA (cytosine-5-)-methyltransferase activity - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_234373_3 1122201.AUAZ01000021_gene3139 6.28e-19 85.1 2CJKM@1|root,314EI@2|Bacteria,1RGVN@1224|Proteobacteria,1T082@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_3154_1 247490.KSU1_C1076 1.01e-19 82.8 2ENVJ@1|root,33GGM@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_243034_1 1336243.JAEA01000002_gene2645 1.12e-07 52.4 28PTM@1|root,2ZCEU@2|Bacteria,1R5DD@1224|Proteobacteria,2TVG7@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Family of unknown function (DUF5309) - - - - - - - - - - - - DUF5309 k59_243034_4 488538.SAR116_0371 5.29e-44 152.0 2CBYP@1|root,33HT7@2|Bacteria,1NJP6@1224|Proteobacteria,2UN9N@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_243034_5 1297863.APJF01000020_gene2704 6.01e-18 95.9 28JTG@1|root,2Z9IR@2|Bacteria,1R0GC@1224|Proteobacteria,2TURR@28211|Alphaproteobacteria,3JUCC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF2793) - - - - - - - - - - - - DUF2793 k59_35809_1 1123023.JIAI01000012_gene9202 4.04e-41 147.0 COG1351@1|root,COG1351@2|Bacteria 2|Bacteria F thymidylate synthase (FAD) activity - - 2.1.1.148 ko:K03465 ko00240,ko00670,ko01100,map00240,map00670,map01100 - R06613 RC00022,RC00332 ko00000,ko00001,ko01000 - - - Thy1 k59_69042_2 1122225.AULQ01000004_gene2180 1.25e-11 63.5 COG1525@1|root,COG1525@2|Bacteria,4NR4U@976|Bacteroidetes,1I3CI@117743|Flavobacteriia 976|Bacteroidetes L Staphylococcal nuclease homologue - - 3.1.31.1 ko:K01174 - - - - ko00000,ko01000 - - - SNase k59_153572_1 1283337.CAPSD_BPHA1 0.000711 44.7 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QJPJ@10662|Myoviridae 10662|Myoviridae S N-acetylmuramoyl-L-alanine amidase activity - GO:0005575,GO:0019012 - - - - - - - - - - - k59_153572_2 278963.ATWD01000001_gene4461 3.54e-05 49.7 COG4653@1|root,COG4653@2|Bacteria 2|Bacteria G Phage capsid family - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_12070_1 1526550.A0A088F6W1_9VIRU 4.13e-15 85.9 4QAK6@10239|Viruses 10239|Viruses S N-acetylmuramoyl-L-alanine amidase activity - - - - - - - - - - - - - k59_36993_1 105154.Q9MBU6_9VIRU 7.82e-121 363.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_36993_5 1385658.U5KNR1_9VIRU 4.38e-68 221.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_36993_7 1385658.U5KPZ6_9VIRU 5.12e-90 283.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_103460_2 1211640.K4JUD3_9CAUD 2.61e-73 234.0 4QB08@10239|Viruses,4QY8E@35237|dsDNA viruses no RNA stage,4QRIV@28883|Caudovirales,4QM5X@10699|Siphoviridae 10699|Siphoviridae S exonuclease activity - - - - - - - - - - - - - k59_178264_1 240016.ABIZ01000001_gene5053 5.97e-36 138.0 2DR7Z@1|root,33AM6@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_170420_1 1692253.A0A0K1RLM4_9CIRC 1.57e-17 82.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_45935_1 1122971.BAME01000009_gene1216 1.21e-53 180.0 COG4422@1|root,COG4422@2|Bacteria,4NJKJ@976|Bacteroidetes,2FNM4@200643|Bacteroidia,22ZBY@171551|Porphyromonadaceae 976|Bacteroidetes S Protein of unknown function (DUF5131) - - - - - - - - - - - - DUF5131 k59_170422_1 1051675.G0YQH1_9CAUD 3.63e-08 61.2 4QAXA@10239|Viruses,4QYJI@35237|dsDNA viruses no RNA stage,4QQ1A@28883|Caudovirales,4QNU7@10744|Podoviridae 10744|Podoviridae S metallopeptidase activity - - - - - - - - - - - - - k59_203353_1 10761.Q716E9_BPSFV 0.000908 44.7 4QEYV@10239|Viruses,4QZ8I@35237|dsDNA viruses no RNA stage,4QTQ6@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_145919_1 716928.AJQT01000109_gene1217 4.79e-47 155.0 2FEUE@1|root,346TC@2|Bacteria,1MZPB@1224|Proteobacteria,2UC4Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_228213_1 1692256.A0A0K1RL85_9CIRC 2e-22 97.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_72003_1 722419.PH505_bb00460 1.73e-21 97.8 COG0270@1|root,COG0270@2|Bacteria,1MV9D@1224|Proteobacteria,1RPD1@1236|Gammaproteobacteria,2Q3YP@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria L C-5 cytosine-specific DNA methylase dcm - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_114053_1 412597.AEPN01000075_gene1392 1.71e-33 127.0 COG0827@1|root,COG0827@2|Bacteria,1R5Y7@1224|Proteobacteria,2VEZS@28211|Alphaproteobacteria,2PX5N@265|Paracoccus 28211|Alphaproteobacteria L Domain of unknown function (DUF4942) - - - - - - - - - - - - DUF4942,MTS k59_114053_3 1280941.HY2_11830 2.99e-16 88.6 COG1475@1|root,COG1475@2|Bacteria,1MVF9@1224|Proteobacteria,2TR0P@28211|Alphaproteobacteria,43XC6@69657|Hyphomonadaceae 28211|Alphaproteobacteria K ParB-like nuclease domain - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_188281_4 1327935.A0A060AMH2_9CAUD 1.77e-09 67.8 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QI82@10662|Myoviridae 10662|Myoviridae S virus tail, fiber - - - - - - - - - - - - - k59_162935_1 35703.DQ02_13760 1.26e-11 62.4 COG4570@1|root,COG4570@2|Bacteria,1RH5J@1224|Proteobacteria,1S7I6@1236|Gammaproteobacteria 1236|Gammaproteobacteria L endodeoxyribonuclease RusA - - - - - - - - - - - - RusA k59_188510_1 742733.HMPREF9469_05033 7.56e-181 522.0 COG4626@1|root,COG4626@2|Bacteria,1TT9I@1239|Firmicutes,24AFK@186801|Clostridia,222GA@1506553|Lachnoclostridium 186801|Clostridia S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_21393_2 1340709.S5WCQ6_9CAUD 3.79e-52 170.0 4QF2I@10239|Viruses,4QZUC@35237|dsDNA viruses no RNA stage,4QTZV@28883|Caudovirales,4QMSD@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_72185_1 1475062.W8TKM5_9CIRC 2.05e-07 60.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_105043_1 1618238.A0A0C5IB41_9CIRC 4.02e-33 132.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_155461_1 1111134.HMPREF1253_1187 2.22e-07 60.8 COG2369@1|root,COG2369@2|Bacteria,1V2JT@1239|Firmicutes,24QQG@186801|Clostridia 186801|Clostridia S Phage Mu protein F like protein - - - - - - - - - - - - Phage_Mu_F k59_87489_1 925775.XVE_4782 9.05e-45 158.0 COG4128@1|root,COG4128@2|Bacteria,1R51Y@1224|Proteobacteria,1T2BV@1236|Gammaproteobacteria,1X750@135614|Xanthomonadales 135614|Xanthomonadales S Zonular occludens toxin (Zot) - - - - - - - - - - - - Zot k59_222739_2 1118153.MOY_16467 4e-78 255.0 28IN7@1|root,2Z8NM@2|Bacteria 2|Bacteria S Capsid protein (F protein) - - - - - - - - - - - - Phage_F k59_97302_2 2003327.CAPSD_BPCHP 3.39e-38 141.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_57091_1 1027292.HMPREF9372_0303 6.21e-08 62.4 COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,4HAG2@91061|Bacilli,26E1G@186818|Planococcaceae 91061|Bacilli L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 k59_57091_3 1556290.A0A0A0RT35_9CAUD 4.3e-59 195.0 4QAWG@10239|Viruses,4QPII@28883|Caudovirales,4QKWY@10699|Siphoviridae 10699|Siphoviridae S DNA helicase activity - - - - - - - - - - - - - k59_115696_1 1051675.G0YQC8_9CAUD 8.17e-48 169.0 4QB3X@10239|Viruses,4QWKP@35237|dsDNA viruses no RNA stage,4QPEE@28883|Caudovirales,4QNCI@10744|Podoviridae 10744|Podoviridae S VWA-like domain (DUF2201) - - - - - - - - - - - - - k59_156703_2 202698.XP_007384096.1 2.65e-08 65.5 COG0749@1|root,KOG3657@2759|Eukaryota,38B9M@33154|Opisthokonta,3NTXD@4751|Fungi,3UYZN@5204|Basidiomycota,2283A@155619|Agaricomycetes,3H2TU@355688|Agaricomycetes incertae sedis 4751|Fungi L DNA polymerase A domain MIP1 GO:0000002,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006264,GO:0006725,GO:0006807,GO:0006996,GO:0007005,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0032042,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02332 ko01100,ko04139,map01100,map04139 M00294 - - ko00000,ko00001,ko00002,ko01000,ko03029,ko03032 - - - DNA_pol_A k59_97303_1 1121937.AUHJ01000007_gene1948 1.41e-31 129.0 COG2911@1|root,COG3941@1|root,COG2911@2|Bacteria,COG3941@2|Bacteria,1MZWI@1224|Proteobacteria,1S51D@1236|Gammaproteobacteria,4682G@72275|Alteromonadaceae 1236|Gammaproteobacteria D Mu-like prophage protein - - - - - - - - - - - - - k59_164236_1 105154.Q9MBU6_9VIRU 5.69e-72 236.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_197023_2 1439940.BAY1663_02346 1.59e-32 126.0 COG0500@1|root,COG0500@2|Bacteria 2|Bacteria Q methyltransferase activity - - - - - - - - - - - - Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_32 k59_197023_3 371042.NG99_06050 2.41e-31 117.0 2DKZC@1|root,30ZS6@2|Bacteria,1RGQ9@1224|Proteobacteria,1S70S@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_156705_3 1206741.BAFX01000172_gene7413 4.27e-09 58.9 2CICW@1|root,346YY@2|Bacteria,2HIJU@201174|Actinobacteria,4G48K@85025|Nocardiaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_264308_1 1385658.U5KPZ6_9VIRU 7.66e-92 289.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_173646_1 1122179.KB890441_gene1070 5.28e-50 174.0 COG1858@1|root,COG1858@2|Bacteria,4NEKS@976|Bacteroidetes,1IVDE@117747|Sphingobacteriia 976|Bacteroidetes C cytochrome C peroxidase mauG - 1.11.1.5 ko:K00428 - - - - ko00000,ko01000 - - - CCP_MauG,Cytochrom_C k59_164241_1 691965.D4P7I3_9CAUD 1.91e-97 315.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_238119_1 1005994.GTGU_00310 1.26e-20 89.7 2DP75@1|root,330U8@2|Bacteria,1N8XA@1224|Proteobacteria,1SCZN@1236|Gammaproteobacteria 1236|Gammaproteobacteria S HNH endonuclease - - - - - - - - - - - - AP2,HNH_3 k59_199155_1 312309.VF_2017 8.97e-48 157.0 2CPEB@1|root,32SIW@2|Bacteria,1MZE0@1224|Proteobacteria,1SARU@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_33355_1 1385658.U5KPZ6_9VIRU 2.73e-187 541.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_165961_1 706587.Desti_2197 7.62e-68 224.0 COG4422@1|root,COG4422@2|Bacteria,1MXQI@1224|Proteobacteria,42WFA@68525|delta/epsilon subdivisions,2X5AZ@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Pfam:Gp37_Gp68 - - - - - - - - - - - - DUF5131 k59_83185_2 1234888.K0A2J2_9VIRU 3.41e-28 112.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_157783_2 280701.Q5QF40_9CAUD 7.63e-28 115.0 4QC5R@10239|Viruses,4QVBN@35237|dsDNA viruses no RNA stage,4QRIY@28883|Caudovirales,4QNY0@10744|Podoviridae 10744|Podoviridae S RyR domain - - - - - - - - - - - - - k59_215869_2 1385658.U5KPZ6_9VIRU 5.19e-158 468.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_166044_1 90813.JQMT01000001_gene1558 1.13e-35 140.0 COG3451@1|root,COG3451@2|Bacteria,1MUEN@1224|Proteobacteria,1RPAY@1236|Gammaproteobacteria,4600S@72273|Thiotrichales 72273|Thiotrichales U F pilus assembly Type-IV secretion system for plasmid transfer - - - - - - - - - - - - TraC_F_IV k59_166044_4 1123487.KB892851_gene319 9.04e-29 125.0 COG3772@1|root,COG3772@2|Bacteria,1MV52@1224|Proteobacteria,2VP37@28216|Betaproteobacteria,2KXRQ@206389|Rhodocyclales 206389|Rhodocyclales S Integrating conjugative element protein - - - - - - - - - - - - - k59_166044_11 883.DvMF_2570 2.81e-42 162.0 COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,42QJ2@68525|delta/epsilon subdivisions,2WM78@28221|Deltaproteobacteria,2M8CT@213115|Desulfovibrionales 28221|Deltaproteobacteria S VWA-like domain (DUF2201) - - - - - - - - - - - - DUF2201,DUF2201_N k59_149428_1 1234888.K0A2J2_9VIRU 1.78e-91 286.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_149428_3 1234888.K0A2R8_9VIRU 3.72e-26 109.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_149428_7 2003327.CAPSD_BPCHP 1.09e-18 92.8 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_116407_1 1283079.M1HMA6_9CAUD 1.86e-68 232.0 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales,4QNBW@10744|Podoviridae 10744|Podoviridae S DNA helicase activity - - - - - - - - - - - - - k59_99752_1 755732.Fluta_3103 2.1e-16 75.1 COG0566@1|root,COG0566@2|Bacteria,4NMEA@976|Bacteroidetes,1I19V@117743|Flavobacteriia,2PBT1@246874|Cryomorphaceae 976|Bacteroidetes J SpoU rRNA Methylase family trmH - 2.1.1.34 ko:K00556 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase k59_50017_2 332101.JIBU02000048_gene3721 2.31e-23 111.0 COG5545@1|root,COG5545@2|Bacteria,1TQNX@1239|Firmicutes,2495S@186801|Clostridia,36EHX@31979|Clostridiaceae 186801|Clostridia S virulence-associated E family protein - - - - - - - - - - - - VirE k59_50017_3 1158607.UAU_01026 5.36e-10 59.7 COG1403@1|root,COG1403@2|Bacteria,1VF1M@1239|Firmicutes,4HNZH@91061|Bacilli,4B6GG@81852|Enterococcaceae 91061|Bacilli V HNH endonuclease - - - ko:K07451 - - - - ko00000,ko01000,ko02048 - - - HNH k59_182659_1 1788439.A0A190WHD0_9CIRC 3.67e-25 108.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_208325_1 134676.ACPL_6931 2.28e-102 325.0 COG4676@1|root,COG4676@2|Bacteria,2GPA6@201174|Actinobacteria,4DCBY@85008|Micromonosporales 201174|Actinobacteria S Protein conserved in bacteria - - - - - - - - - - - - - k59_258530_2 1166016.W5S_2328 9.05e-79 250.0 2CI0W@1|root,2Z81W@2|Bacteria,1R9FZ@1224|Proteobacteria,1S0NA@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage X family - - - - - - - - - - - - Phage_CRI,Phage_X k59_167111_14 1188795.K7ZMK0_9CAUD 5.21e-50 176.0 4QE1R@10239|Viruses,4R08Y@35237|dsDNA viruses no RNA stage,4QUAF@28883|Caudovirales,4QNMU@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_167111_21 1122201.AUAZ01000017_gene2962 4.88e-14 83.6 COG4675@1|root,COG4675@2|Bacteria 2|Bacteria M tail collar domain protein - - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - Collar,Phage_fiber_2 k59_167111_26 1121033.AUCF01000017_gene3816 9.62e-39 135.0 COG0741@1|root,COG0741@2|Bacteria,1N0U8@1224|Proteobacteria,2UICK@28211|Alphaproteobacteria,2JTZJ@204441|Rhodospirillales 204441|Rhodospirillales M lytic transglycosylase activity - - - - - - - - - - - - - k59_142379_1 1120936.KB907208_gene1107 3.52e-130 394.0 COG0209@1|root,COG0209@2|Bacteria,2IC1H@201174|Actinobacteria 201174|Actinobacteria F Ribonucleotide reductase, barrel domain - - - - - - - - - - - - Ribonuc_red_lgC k59_9442_2 1379698.RBG1_1C00001G0866 0.000109 53.5 COG1674@1|root,COG1674@2|Bacteria,2NNVB@2323|unclassified Bacteria 2|Bacteria D Ftsk_gamma ftsK - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma k59_51181_1 691965.D4P7D6_9CAUD 1.83e-84 285.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_200266_14 1095737.HMPREF1110_1221 1.44e-18 88.6 COG1783@1|root,COG1783@2|Bacteria,1TRQP@1239|Firmicutes,4HDMY@91061|Bacilli,2TPYB@28037|Streptococcus mitis 91061|Bacilli S Terminase RNAseH like domain yqaT - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C k59_92598_3 1410628.JNKS01000024_gene1700 3.28e-08 58.5 2D8IU@1|root,32TRD@2|Bacteria,1V92T@1239|Firmicutes,24KTR@186801|Clostridia,27Q4N@186928|unclassified Lachnospiraceae 186801|Clostridia - - - - - - - - - - - - - - - k59_159814_1 1379715.S5TMW6_9CIRC 1.41e-12 72.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_77288_1 314271.RB2654_08182 5.75e-48 165.0 COG0451@1|root,COG0451@2|Bacteria,1MUGT@1224|Proteobacteria,2TRF6@28211|Alphaproteobacteria 28211|Alphaproteobacteria GM Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction - - 1.1.1.271 ko:K02377 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R05692 RC01014 ko00000,ko00001,ko01000 - - - Epimerase k59_176516_1 768066.HELO_2646 1.83e-32 130.0 COG4626@1|root,COG4626@2|Bacteria,1R2FH@1224|Proteobacteria,1RN1F@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Terminase - - - - - - - - - - - - - k59_27901_1 1415146.V5Q8Q5_9CAUD 8.41e-43 159.0 4QBMV@10239|Viruses,4QUU6@35237|dsDNA viruses no RNA stage,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_201659_1 1123279.ATUS01000005_gene3110 8.93e-71 234.0 COG1196@1|root,COG2911@1|root,COG1196@2|Bacteria,COG2911@2|Bacteria 2|Bacteria S protein secretion sca1 - - - - - - - - - - - Autotransporter,DUF4114,SLT,Tape_meas_lam_C,VPEP k59_10593_2 293178.A8R8S3_9CAUD 7.71e-28 120.0 4QBG4@10239|Viruses,4QUZA@35237|dsDNA viruses no RNA stage,4QRSK@28883|Caudovirales,4QJW4@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_110588_1 1121445.ATUZ01000013_gene1155 3.78e-17 89.7 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2WJ3W@28221|Deltaproteobacteria,2M7UN@213115|Desulfovibrionales 28221|Deltaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_260020_1 347834.RHE_CH02927 6.42e-25 111.0 COG0740@1|root,COG0740@2|Bacteria,1MUQ9@1224|Proteobacteria,2U37W@28211|Alphaproteobacteria,4BEJX@82115|Rhizobiaceae 28211|Alphaproteobacteria OU Clp protease - - - - - - - - - - - - CLP_protease k59_93628_1 1094508.Tsac_2145 1.52e-06 57.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia,42FDS@68295|Thermoanaerobacterales 186801|Clostridia L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_52670_2 1430331.EP10_10445 9.51e-17 78.6 COG3405@1|root,COG3405@2|Bacteria,1VBUA@1239|Firmicutes,4HMXV@91061|Bacilli 91061|Bacilli G Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - - - - - - - - - - - k59_135548_1 1692250.A0A0K1RLR1_9CIRC 1.57e-114 340.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_127462_4 1121456.ATVA01000013_gene976 7.34e-16 75.9 2C4D9@1|root,337PW@2|Bacteria,1NE4W@1224|Proteobacteria,42QXQ@68525|delta/epsilon subdivisions,2WMPR@28221|Deltaproteobacteria,2MB2C@213115|Desulfovibrionales 28221|Deltaproteobacteria S Protein of unknown function (DUF1353) - - - - - - - - - - - - DUF1353 k59_152249_4 689781.AUJX01000003_gene2841 1.02e-07 54.3 2BWFY@1|root,32F7Q@2|Bacteria,1V8E5@1239|Firmicutes,25AXH@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_201667_1 1609634.A0A0C5ANA6_9VIRU 2.69e-05 51.6 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_44168_2 1231377.C426_0888 1.55e-11 61.2 2DG0P@1|root,2ZTZD@2|Bacteria 2|Bacteria S Putative lactococcus lactis phage r1t holin - - - - - - - - - - - - Phage_r1t_holin k59_44168_3 1068980.ARVW01000001_gene6272 3.77e-07 53.1 COG3409@1|root,COG3409@2|Bacteria,2GR1Q@201174|Actinobacteria,4DYAX@85010|Pseudonocardiales 201174|Actinobacteria M Peptidoglycan-binding domain 1 protein - - - - - - - - - - - - CHAP,LysM,PG_binding_1 k59_234314_3 1121929.KB898702_gene248 1.02e-16 75.9 COG1591@1|root,COG1591@2|Bacteria,1VAAB@1239|Firmicutes,4HP2S@91061|Bacilli 91061|Bacilli L Archaeal holliday junction resolvase (hjc) - - - - - - - - - - - - Hjc,VRR_NUC k59_135550_1 753085.F4YCV3_9CAUD 2.77e-139 421.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_102162_2 742740.HMPREF9474_02303 8.63e-66 228.0 2EWZQ@1|root,33QB0@2|Bacteria,1V0T1@1239|Firmicutes,249Z2@186801|Clostridia,221YV@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_144099_1 1609634.A0A0C5ANA6_9VIRU 2.55e-09 62.0 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_3066_1 1220601.L7TLX3_9CAUD 3.17e-118 357.0 4QF7H@10239|Viruses,4R06M@35237|dsDNA viruses no RNA stage,4QQTS@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_85087_1 1123368.AUIS01000020_gene1078 7.72e-18 83.2 28XPA@1|root,2ZJK5@2|Bacteria,1P9T2@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_36949_2 1197477.IA57_12340 5.73e-12 66.6 2DMPB@1|root,32SV8@2|Bacteria,4NSG4@976|Bacteroidetes,1I3FJ@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_112298_1 1476888.X4YH18_9CAUD 5.19e-27 102.0 4QG3V@10239|Viruses,4QW5T@35237|dsDNA viruses no RNA stage,4QSWE@28883|Caudovirales,4QM1Q@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_112298_2 691965.D4P7L6_9CAUD 1.48e-69 216.0 4QFKG@10239|Viruses,4QV77@35237|dsDNA viruses no RNA stage,4QR6Q@28883|Caudovirales,4QMGT@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_178236_2 520999.PROVALCAL_01867 5.36e-37 128.0 COG3179@1|root,COG3179@2|Bacteria,1RE8K@1224|Proteobacteria,1S4U8@1236|Gammaproteobacteria,3Z9BP@586|Providencia 1236|Gammaproteobacteria S D-alanyl-D-alanine carboxypeptidase - - - - - - - - - - - - Peptidase_M15_4 k59_86163_2 114777.Q9T1P2_9CAUD 2.25e-07 59.3 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QII1@10662|Myoviridae 10662|Myoviridae S N-methyltransferase activity - - - - - - - - - - - - - k59_54359_1 1500301.JQMF01000006_gene1755 9.43e-61 208.0 28MSK@1|root,2ZB0X@2|Bacteria,1R7CY@1224|Proteobacteria,2U2MY@28211|Alphaproteobacteria,4BJ92@82115|Rhizobiaceae 28211|Alphaproteobacteria S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_29582_1 1385658.U5KPZ6_9VIRU 1.27e-60 204.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_210909_1 1234888.K0A2J2_9VIRU 3.59e-43 159.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_20134_1 99598.Cal7507_0002 7.58e-134 395.0 COG0592@1|root,COG0592@2|Bacteria,1FZV5@1117|Cyanobacteria,1HM05@1161|Nostocales 1117|Cyanobacteria L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 k59_120728_1 1144313.PMI10_00662 1.99e-24 107.0 2C0EQ@1|root,3492A@2|Bacteria,4P5TY@976|Bacteroidetes,1IAIT@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_61627_1 1110697.NCAST_19_01310 2.17e-09 62.8 2F0TV@1|root,33TVT@2|Bacteria,2IM2V@201174|Actinobacteria,4FXMU@85025|Nocardiaceae 201174|Actinobacteria S Glutamine amidotransferases class-II - - - - - - - - - - - - GATase_4 k59_261547_1 1122201.AUAZ01000017_gene2950 1.63e-44 163.0 COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,1RY1X@1236|Gammaproteobacteria,46BED@72275|Alteromonadaceae 1236|Gammaproteobacteria S associated with various cellular activities - - - - - - - - - - - - AAA,AAA_5 k59_103567_3 644968.DFW101_3033 1.45e-23 96.3 2CICW@1|root,346YY@2|Bacteria,1QEB4@1224|Proteobacteria,435YB@68525|delta/epsilon subdivisions,2X9DP@28221|Deltaproteobacteria,2MC47@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_46065_2 1121121.KB894304_gene3341 2.59e-28 108.0 2CA0E@1|root,349DP@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_80090_5 321332.CYB_1781 2.95e-17 87.0 COG1351@1|root,COG1351@2|Bacteria,1G1PU@1117|Cyanobacteria,1GYHJ@1129|Synechococcus 1117|Cyanobacteria F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant thyX - 2.1.1.148 ko:K03465 ko00240,ko00670,ko01100,map00240,map00670,map01100 - R06613 RC00022,RC00332 ko00000,ko00001,ko01000 - - - HNH,Intein_splicing,Thy1 k59_80090_7 753084.F4YCG7_9CAUD 4.06e-17 82.0 4QAR6@10239|Viruses,4QUTK@35237|dsDNA viruses no RNA stage,4QPS2@28883|Caudovirales,4QKTM@10699|Siphoviridae 10699|Siphoviridae S dUTPase - GO:0003674,GO:0003824,GO:0004170,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0047429 - - - - - - - - - - - k59_172112_2 1416009.V9VHP8_9CAUD 1.8e-20 89.0 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales,4QNBQ@10744|Podoviridae 10744|Podoviridae S HNH endonuclease - - - - - - - - - - - - - k59_138852_1 444861.E3SPN9_9CAUD 3.79e-34 134.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales 28883|Caudovirales S DNA polymerase family B - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016032,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019058,GO:0019079,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0039686,GO:0039693,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044403,GO:0044419,GO:0046483,GO:0051704,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_138852_2 1150989.H6WXG4_9CAUD 9.08e-37 135.0 4QG24@10239|Viruses,4QV8E@35237|dsDNA viruses no RNA stage,4QSGP@28883|Caudovirales,4QM3Q@10699|Siphoviridae 10699|Siphoviridae S (deoxy)nucleoside-phosphate kinase activity - GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0044237,GO:0047507 - - - - - - - - - - - k59_138852_3 926560.KE387027_gene333 8.44e-17 79.7 COG0207@1|root,COG0207@2|Bacteria,1WM4Z@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA - 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt k59_122400_1 691966.D4P728_9CAUD 1.68e-08 63.5 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_205005_1 1079460.ATTQ01000019_gene4437 9.13e-54 189.0 2CC8M@1|root,308VJ@2|Bacteria,1R789@1224|Proteobacteria,2U2NB@28211|Alphaproteobacteria,4BHET@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_195744_1 875328.JDM601_0775 3.72e-51 187.0 2EP1Y@1|root,33GNT@2|Bacteria,2IC2I@201174|Actinobacteria,2380S@1762|Mycobacteriaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_253635_2 40215.BBOS01000001_gene740 4.82e-19 86.7 2EFG7@1|root,3398W@2|Bacteria 2|Bacteria L Recombination endonuclease VII - - - - - - - - - - - - Endonuclease_7 k59_188492_1 1562701.BBOF01000081_gene240 2.19e-32 138.0 COG0749@1|root,COG0749@2|Bacteria,1MWX7@1224|Proteobacteria,2VMZW@28216|Betaproteobacteria 28216|Betaproteobacteria L DNA polymerase family A - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_188492_2 658187.LDG_6143 1.77e-21 102.0 COG0467@1|root,COG1119@1|root,COG0467@2|Bacteria,COG1119@2|Bacteria 2|Bacteria P ATPase activity - - - ko:K03546,ko:K06919,ko:K07452,ko:K08482,ko:K09384,ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko01000,ko02042,ko02048,ko03400 - - - AAA_11,AAA_12,AAA_25,DUF4011 k59_6652_2 1123034.JMKP01000004_gene1720 2.79e-15 82.8 2CHRY@1|root,30Z9E@2|Bacteria,1RGQK@1224|Proteobacteria,1T1AM@1236|Gammaproteobacteria,3NKV5@468|Moraxellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - RecT k59_253642_2 1051673.G0YQ57_9CAUD 3.1e-13 69.7 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QNX8@10744|Podoviridae 10744|Podoviridae S N-acetylmuramoyl-L-alanine amidase activity - GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0008150,GO:0008745,GO:0016032,GO:0016787,GO:0016810,GO:0016811,GO:0019048,GO:0019058,GO:0019076,GO:0031640,GO:0032897,GO:0035821,GO:0035890,GO:0035891,GO:0039633,GO:0040011,GO:0043900,GO:0043901,GO:0043903,GO:0044003,GO:0044004,GO:0044364,GO:0044403,GO:0044419,GO:0044659,GO:0044661,GO:0046782,GO:0048519,GO:0048525,GO:0050789,GO:0050792,GO:0051701,GO:0051704,GO:0051817,GO:0051818,GO:0051883,GO:0052126,GO:0052192,GO:0061783,GO:0065007 - - - - - - - - - - - k59_14656_1 145579.CAPSD_BPPHM 5.55e-71 233.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_140432_1 553218.CAMRE0001_2362 2.12e-06 48.1 2DHSF@1|root,300RT@2|Bacteria,1Q6F5@1224|Proteobacteria,432SB@68525|delta/epsilon subdivisions,2YSQ5@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria S Bacterial mobilization protein MobC - - - - - - - - - - - - MobC k59_140432_2 1225785.CM001983_gene3570 1.17e-77 260.0 2AQWX@1|root,31G5F@2|Bacteria,1N36S@1224|Proteobacteria,1S9CB@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Relaxase/Mobilisation nuclease domain - - - - - - - - - - - - Relaxase k59_149236_1 1279017.AQYJ01000028_gene2239 4.97e-11 69.3 COG4675@1|root,COG4675@2|Bacteria,1RESM@1224|Proteobacteria,1S7DU@1236|Gammaproteobacteria 1236|Gammaproteobacteria S tail collar domain protein - - - - - - - - - - - - DUF3751 k59_64059_2 1041142.ATTP01000021_gene172 2.85e-16 88.6 2DE5J@1|root,2ZKKF@2|Bacteria,1NHAR@1224|Proteobacteria,2U4YI@28211|Alphaproteobacteria,4BP0X@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_22948_1 532078.B3VCJ7_9CAUD 8.71e-52 183.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_213465_2 2003327.CAPSD_BPCHP 7.69e-20 92.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_231188_2 1165094.RINTHH_3920 4.06e-78 249.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_213575_1 1029823.AFIE01000007_gene1883 3.22e-17 92.8 29KX8@1|root,307UQ@2|Bacteria,1RK1N@1224|Proteobacteria,1SNEN@1236|Gammaproteobacteria,3NJMI@468|Moraxellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_73811_1 216594.MMAR_3921 6.86e-34 128.0 COG0270@1|root,COG0270@2|Bacteria,2I8R8@201174|Actinobacteria 201174|Actinobacteria H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_164523_2 525282.HMPREF0391_10171 5.58e-12 72.0 COG2887@1|root,COG2887@2|Bacteria,1TPIC@1239|Firmicutes,247TB@186801|Clostridia,22H2H@1570339|Peptoniphilaceae 186801|Clostridia L Protein of unknown function (DUF2800) - - - - - - - - - - - - DUF2800 k59_115875_2 411460.RUMTOR_01350 4.64e-11 63.5 2EAAT@1|root,334F2@2|Bacteria,1VJJI@1239|Firmicutes,24TQU@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_81556_1 337191.KTR9_4547 4.89e-20 86.3 COG0328@1|root,COG0328@2|Bacteria,2GK53@201174|Actinobacteria,4GDT3@85026|Gordoniaceae 201174|Actinobacteria L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhA - 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_H k59_190471_4 1234888.K0A2J2_9VIRU 1.83e-107 336.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_264549_1 1218103.CIN01S_12_00080 4.63e-08 59.7 COG5295@1|root,COG5295@2|Bacteria,4P9G5@976|Bacteroidetes,1IM3T@117743|Flavobacteriia,3ZU4G@59732|Chryseobacterium 976|Bacteroidetes UW Hep Hag repeat protein - - - - - - - - - - - - - k59_197299_3 945550.VISI1226_13668 5.64e-16 75.1 2DNV9@1|root,32ZB3@2|Bacteria,1MZGP@1224|Proteobacteria,1SE04@1236|Gammaproteobacteria,1XY7K@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k59_81559_1 1204521.I7B2R4_9CAUD 6.01e-48 162.0 4QF3X@10239|Viruses,4QWSV@35237|dsDNA viruses no RNA stage,4QT5P@28883|Caudovirales 28883|Caudovirales S oxidoreductase activity - - - - - - - - - - - - - k59_141391_2 1692250.A0A0K1RLR1_9CIRC 6.26e-33 123.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_166199_1 742823.HMPREF9465_00202 2.58e-05 54.7 COG4675@1|root,COG4675@2|Bacteria,1RESM@1224|Proteobacteria,2VTNP@28216|Betaproteobacteria 28216|Betaproteobacteria S tail collar domain protein - - - - - - - - - - - - DUF3751 k59_216067_1 691965.D4P7I3_9CAUD 1.4e-119 377.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_191110_4 469371.Tbis_2770 2.08e-08 55.8 COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,2GXAS@201174|Actinobacteria,4EF8S@85010|Pseudonocardiales 201174|Actinobacteria K Helix-turn-helix domain - - - - - - - - - - - - Cupin_2,HTH_3,HTH_31 k59_216075_1 105154.Q9MBU3_9VIRU 1.06e-11 68.2 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_58475_2 369723.Strop_0517 6.88e-78 243.0 2EES9@1|root,338JX@2|Bacteria,2H5MY@201174|Actinobacteria 201174|Actinobacteria L RNase_H superfamily - - - - - - - - - - - - RNase_H_2 k59_240899_2 1609634.A0A0C5AFV4_9VIRU 2.48e-50 184.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_240955_2 1165094.RINTHH_3920 2.79e-50 172.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_116605_1 105154.Q9MBU0_9VIRU 1.11e-52 179.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_174846_1 1609634.A0A0C5AFV4_9VIRU 4.12e-55 189.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_42490_2 272952.HpaP809118 1.39e-13 83.6 COG0553@1|root,KOG0384@2759|Eukaryota,3QB66@4776|Peronosporales 4776|Peronosporales K SNF2 family N-terminal domain - - 3.6.4.12 ko:K14437 - - - - ko00000,ko01000,ko03036 - - - Chromo,Helicase_C,SNF2_N k59_34292_1 1122194.AUHU01000005_gene951 1.64e-70 228.0 COG4128@1|root,COG4128@2|Bacteria,1N0I7@1224|Proteobacteria,1SAH8@1236|Gammaproteobacteria,46BMP@72275|Alteromonadaceae 1236|Gammaproteobacteria S Zonular occludens toxin (Zot) zot GO:0001906,GO:0006810,GO:0006996,GO:0007010,GO:0008150,GO:0009405,GO:0009987,GO:0016043,GO:0031640,GO:0035821,GO:0042044,GO:0042045,GO:0044364,GO:0044419,GO:0051179,GO:0051234,GO:0051704,GO:0070633,GO:0071840 - ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko02042 - - - Zot k59_92275_1 1788454.A0A190WHE4_9CIRC 3.62e-34 129.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_133781_1 268746.Q58ML2_BPPRM 6.03e-38 143.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QI9F@10662|Myoviridae 10662|Myoviridae S Type III restriction enzyme, res subunit - - - - - - - - - - - - - k59_42599_3 2003327.CAPSD_BPCHP 7.35e-32 124.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_125618_2 1589298.A0A0B5GYS4_9CAUD 1.6e-110 331.0 4QC2G@10239|Viruses,4QPRR@28883|Caudovirales,4QM50@10699|Siphoviridae 10699|Siphoviridae S Ribonucleotide reductase, small chain - - - - - - - - - - - - - k59_75817_1 1381123.AYOD01000005_gene1225 2.59e-64 207.0 COG3179@1|root,COG3179@2|Bacteria,1R71F@1224|Proteobacteria,2VF0B@28211|Alphaproteobacteria,43R6I@69277|Phyllobacteriaceae 28211|Alphaproteobacteria M Peptidoglycan-binding domain 1 protein - - - - - - - - - - - - Glyco_hydro_19,Peptidase_M15_4 k59_174943_1 469610.HMPREF0189_01104 1.96e-28 118.0 COG1783@1|root,COG5323@1|root,COG1783@2|Bacteria,COG5323@2|Bacteria 2|Bacteria M Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_174943_4 1057002.KB905370_gene5890 7.23e-28 123.0 COG3064@1|root,COG3064@2|Bacteria,1R6JV@1224|Proteobacteria,2U5NE@28211|Alphaproteobacteria,4BCUU@82115|Rhizobiaceae 28211|Alphaproteobacteria M Membrane - - - - - - - - - - - - - k59_100591_1 1124991.MU9_2905 4.46e-129 381.0 COG5565@1|root,COG5565@2|Bacteria,1R6R3@1224|Proteobacteria,1RY0J@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C k59_142212_5 1527469.A0A076G6N0_9CAUD 6.95e-19 83.6 4QGDB@10239|Viruses,4QSG0@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_117230_1 1122197.ATWI01000011_gene460 1.99e-67 223.0 COG0433@1|root,COG0433@2|Bacteria,1QTVP@1224|Proteobacteria,1T1IQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Zonular occludens toxin (Zot) - - - ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko02042 - - - Zot k59_26772_2 105154.Q9MBU3_9VIRU 6.57e-12 70.1 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_26772_3 105154.Q9MBU6_9VIRU 7.11e-45 160.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_167623_1 643867.Ftrac_3449 3.78e-05 55.1 COG2834@1|root,COG4733@1|root,COG2834@2|Bacteria,COG4733@2|Bacteria,4NWHN@976|Bacteroidetes,47UQ6@768503|Cytophagia 976|Bacteroidetes M Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - - - - - - - - - - VCBS k59_43254_1 283699.D172_4039 1.26e-20 88.2 COG3772@1|root,COG3772@2|Bacteria,1N0ZQ@1224|Proteobacteria,1S9AE@1236|Gammaproteobacteria,2Q38I@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S Phage lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_117994_1 926550.CLDAP_36010 2.85e-30 129.0 COG3103@1|root,COG3103@2|Bacteria 2|Bacteria T Sh3 type 3 domain protein - - 3.5.1.28 ko:K01448,ko:K07448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko02048,ko03036 - - - Muraidase,SH3_3,SLH k59_101112_2 201846.B5SP22_9CAUD 5.58e-31 118.0 4QBNM@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_101112_3 1150474.JQJI01000001_gene1787 7.74e-26 103.0 COG1351@1|root,COG1351@2|Bacteria,2GC26@200918|Thermotogae 200918|Thermotogae F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant thyX - 2.1.1.148 ko:K03465 ko00240,ko00670,ko01100,map00240,map00670,map01100 - R06613 RC00022,RC00332 ko00000,ko00001,ko01000 - - - Thy1 k59_109400_1 1385658.U5KPZ6_9VIRU 8.16e-19 85.9 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_117996_2 1121382.JQKG01000015_gene1742 8.41e-05 48.1 COG2852@1|root,COG2852@2|Bacteria 2|Bacteria L Protein conserved in bacteria - - 2.1.1.72 ko:K07316 - - - - ko00000,ko01000,ko02048 - - - - k59_59632_1 314265.R2601_22796 1.07e-46 195.0 COG4733@1|root,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria,2TV2W@28211|Alphaproteobacteria 28211|Alphaproteobacteria S COG4733 Phage-related protein, tail component - - - - - - - - - - - - Phage-tail_3 k59_17918_4 1609634.A0A0C5AFT2_9VIRU 3.12e-55 189.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_2816_3 742722.HMPREF9463_00216 3.42e-30 114.0 COG0270@1|root,COG0270@2|Bacteria,2IF94@201174|Actinobacteria,4CVQX@84998|Coriobacteriia 84998|Coriobacteriia H C-5 cytosine-specific DNA methylase - - - - - - - - - - - - DNA_methylase k59_127204_2 1280944.HY17_04460 4.53e-78 248.0 COG3723@1|root,COG3723@2|Bacteria,1QZ88@1224|Proteobacteria 1224|Proteobacteria L RecT family - - - ko:K07455 - - - - ko00000,ko03400 - - - RecT k59_168576_1 1429916.X566_20010 2.67e-21 89.4 COG1917@1|root,COG1917@2|Bacteria,1N6Q0@1224|Proteobacteria,2UKI2@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Cupin 2, conserved barrel domain protein - - - - - - - - - - - - - k59_184731_1 1220717.L7TND1_9VIRU 1.69e-13 80.1 4QAK6@10239|Viruses 10239|Viruses S N-acetylmuramoyl-L-alanine amidase activity - GO:0005575,GO:0018995,GO:0019012,GO:0030430,GO:0033643,GO:0033646,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_43956_1 522306.CAP2UW1_0329 3.42e-18 87.8 COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,2VGZ6@28216|Betaproteobacteria 28216|Betaproteobacteria L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD recD2 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 k59_27616_1 279238.Saro_3004 4.68e-83 261.0 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1NKZK@1224|Proteobacteria,2U0EG@28211|Alphaproteobacteria,2KC8R@204457|Sphingomonadales 204457|Sphingomonadales S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6C k59_201430_1 1175654.A0A0S0N897_9CAUD 6.67e-132 396.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QM52@10699|Siphoviridae 10699|Siphoviridae S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor - - - - - - - - - - - - - k59_259790_2 1618237.A0A0C5IMG6_9CIRC 1.1e-21 99.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_44037_2 1986029.Q9MBM7_9VIRU 2.55e-18 85.9 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_44037_3 1385658.U5KPZ6_9VIRU 1.02e-56 192.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_68784_2 1609634.A0A0C5AFV4_9VIRU 5.75e-89 280.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_35606_4 766499.C357_17900 5.34e-12 68.2 COG3598@1|root,COG3598@2|Bacteria,1PWN4@1224|Proteobacteria,2U39N@28211|Alphaproteobacteria 28211|Alphaproteobacteria L AAA domain - - - - - - - - - - - - AAA_25,PriCT_1,Prim-Pol k59_18646_1 439375.Oant_0230 3e-56 184.0 COG0270@1|root,COG0270@2|Bacteria,1R5MR@1224|Proteobacteria,2U53Z@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_176461_2 1692252.A0A0K1RL35_9CIRC 5.37e-132 384.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_218776_2 1088864.G8IEC3_9CAUD 5.52e-11 65.9 4QARC@10239|Viruses,4QV4E@35237|dsDNA viruses no RNA stage,4QPDS@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_44042_1 105154.Q9MBU0_9VIRU 2.82e-12 66.6 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_242799_3 1385658.U5KPZ6_9VIRU 5.31e-201 577.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_242799_4 105154.Q9MBU3_9VIRU 1.01e-10 62.4 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_218777_1 290633.GOX2477 3.87e-59 197.0 2CHRY@1|root,30Z9E@2|Bacteria,1RGQK@1224|Proteobacteria,2U9J0@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - RecT k59_193073_7 32024.JMTI01000005_gene1292 2.04e-17 80.9 COG3772@1|root,COG3772@2|Bacteria,1N0ZQ@1224|Proteobacteria,42V55@68525|delta/epsilon subdivisions,2YQNT@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria S lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_35940_1 29486.NJ56_17765 3.39e-25 101.0 COG1896@1|root,COG1896@2|Bacteria,1RACF@1224|Proteobacteria,1S2SY@1236|Gammaproteobacteria,41G0U@629|Yersinia 1236|Gammaproteobacteria S 5'-deoxynucleotidase activity yfdR GO:0002953,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050897 - ko:K06952 - - - - ko00000 - - - - k59_93886_1 1673638.A0A0H4AJL5_9CIRC 7.12e-16 81.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_111034_2 1316936.K678_11231 5.37e-09 60.5 COG3772@1|root,COG3772@2|Bacteria,1N0ZQ@1224|Proteobacteria,2UFT6@28211|Alphaproteobacteria,2JUJF@204441|Rhodospirillales 204441|Rhodospirillales G lysozyme - - - - - - - - - - - - Phage_lysozyme k59_202002_1 1408428.JNJP01000007_gene1930 7.36e-07 58.2 COG0582@1|root,COG0582@2|Bacteria,1MVZB@1224|Proteobacteria,42M9T@68525|delta/epsilon subdivisions,2WNVF@28221|Deltaproteobacteria,2M8MI@213115|Desulfovibrionales 28221|Deltaproteobacteria L Belongs to the 'phage' integrase family - - - ko:K03733 - - - - ko00000,ko03036 - - - Phage_integrase k59_152660_1 490913.C4NTE4_9CAUD 3.15e-59 201.0 4QBYE@10239|Viruses,4QVYH@35237|dsDNA viruses no RNA stage,4QQTP@28883|Caudovirales,4QP46@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_152660_2 1477404.A0A023NH77_9CAUD 2.35e-53 189.0 4QFFI@10239|Viruses,4R00C@35237|dsDNA viruses no RNA stage,4QRHK@28883|Caudovirales,4QNX0@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_185291_1 913970.F8RW84_9VIRU 2.98e-09 63.2 4QCVK@10239|Viruses,4QUMV@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_219391_1 1129146.H2BDG4_9CAUD 2.45e-34 127.0 4QEW7@10239|Viruses,4QYXF@35237|dsDNA viruses no RNA stage,4QTWH@28883|Caudovirales,4QKKW@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_60627_1 1385658.U5KPZ6_9VIRU 1.2e-115 356.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_44501_3 1288079.AUKN01000006_gene3164 8.4e-22 92.0 COG0629@1|root,COG0629@2|Bacteria,2H5FY@201174|Actinobacteria 201174|Actinobacteria L Single-strand binding protein family - - - - - - - - - - - - SSB k59_127812_1 443152.MDG893_20549 1.4e-49 183.0 COG4733@1|root,COG4733@2|Bacteria,1R77Q@1224|Proteobacteria,1S1WT@1236|Gammaproteobacteria,469QU@72275|Alteromonadaceae 1236|Gammaproteobacteria S Fibronectin type 3 domain - - - - - - - - - - - - - k59_219395_1 626887.J057_01640 4.51e-38 145.0 2DBPZ@1|root,2ZABJ@2|Bacteria,1R7CU@1224|Proteobacteria,1SKX7@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_36033_1 691965.D4P7I3_9CAUD 3.97e-85 281.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_169186_1 1234888.K0A2J2_9VIRU 2e-113 346.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_227013_1 667014.Thein_0190 5.97e-20 92.0 COG1191@1|root,COG1191@2|Bacteria,2GHGC@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria K Sigma-70, region 4 - - - ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 - - - ko00000,ko00001,ko02035,ko03021 - - - Sigma70_r2,Sigma70_r3,Sigma70_r4 k59_135855_2 484895.A9J702_BPLUZ 3.09e-24 98.6 4QGGJ@10239|Viruses,4R0EM@35237|dsDNA viruses no RNA stage,4QTQW@28883|Caudovirales,4QNRW@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_19050_3 1618238.A0A0C5IB41_9CIRC 2.24e-16 82.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_153189_1 1234888.K0A2J2_9VIRU 1.13e-99 308.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_177519_2 759362.KVU_1651 4.66e-28 109.0 COG3179@1|root,COG3179@2|Bacteria,1R71F@1224|Proteobacteria,2UD1N@28211|Alphaproteobacteria 28211|Alphaproteobacteria S chitinase - - - - - - - - - - - - Glyco_hydro_19 k59_11338_2 2003327.CAPSD_BPCHP 6.13e-29 116.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_136291_1 1453501.JELR01000001_gene2555 1.31e-188 532.0 COG0270@1|root,COG0270@2|Bacteria,1MV9D@1224|Proteobacteria,1RPD1@1236|Gammaproteobacteria,4667K@72275|Alteromonadaceae 1236|Gammaproteobacteria L C-5 cytosine-specific DNA methylase dcm - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_227530_2 742767.HMPREF9456_03390 2.16e-77 241.0 COG0175@1|root,COG0175@2|Bacteria,4PNYM@976|Bacteroidetes,2G11I@200643|Bacteroidia,230XX@171551|Porphyromonadaceae 2|Bacteria EH Phosphoadenosine phosphosulfate reductase family - - - - - - - - - - - - PAPS_reduct k59_4197_1 444861.E3SPL8_9CAUD 2.08e-47 165.0 4QAIK@10239|Viruses,4QUPH@35237|dsDNA viruses no RNA stage,4QPEB@28883|Caudovirales 28883|Caudovirales S phosphoprotein phosphatase activity - - - - - - - - - - - - - k59_145203_2 1692252.A0A0K1RL35_9CIRC 2.65e-31 127.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_53641_1 1234888.K0A2J2_9VIRU 9.03e-35 132.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_111636_4 1234888.K0A2J2_9VIRU 1.48e-125 381.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_197078_4 691965.D4P7I0_9CAUD 1.21e-36 137.0 4QDSZ@10239|Viruses,4QXJ8@35237|dsDNA viruses no RNA stage,4QPKE@28883|Caudovirales,4QM8R@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_22988_1 1234888.K0A2J2_9VIRU 4.26e-112 343.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_81462_3 10855.CAPSD_SPV4 4.7e-29 118.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_140491_2 35841.BT1A1_2001 2.46e-10 66.2 COG0258@1|root,COG0258@2|Bacteria,1TQ05@1239|Firmicutes,4H9UW@91061|Bacilli,1ZB2Z@1386|Bacillus 91061|Bacilli L 5'3' exonuclease ypcP - - - - - - - - - - - 5_3_exonuc,5_3_exonuc_N k59_173812_3 1520935.A0A0H3UB63_9CIRC 1.5e-25 110.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_140492_1 459349.CLOAM0416 5.51e-11 68.6 COG0463@1|root,COG0463@2|Bacteria,2NPA5@2323|unclassified Bacteria 2|Bacteria M Glycosyl transferase family 2 kdtX - - ko:K12984 - - - - ko00000,ko01000,ko01003,ko01005,ko02000 4.D.1.3 GT2 - Glycos_transf_2 k59_132051_1 1094496.m07a_08960 5.83e-36 136.0 28MVD@1|root,2ZB2Y@2|Bacteria,1R8NK@1224|Proteobacteria,2U265@28211|Alphaproteobacteria,48TXM@772|Bartonellaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF4043) - - - - - - - - - - - - DUF4043 k59_124016_2 1234888.K0A2R8_9VIRU 2.86e-19 93.6 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_124016_4 1609634.A0A0C5AFV4_9VIRU 3.72e-34 136.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_164436_1 1123269.NX02_21935 2.69e-58 196.0 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,2U6BJ@28211|Alphaproteobacteria,2K2MZ@204457|Sphingomonadales 204457|Sphingomonadales S Phage portal protein - - - - - - - - - - - - Phage_portal k59_264470_1 1385658.U5KPZ6_9VIRU 3.88e-93 289.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_14728_1 1118235.CAJH01000041_gene2650 1.75e-56 206.0 COG0740@1|root,COG0740@2|Bacteria,1MUQ9@1224|Proteobacteria,1RRQA@1236|Gammaproteobacteria,1X3TK@135614|Xanthomonadales 135614|Xanthomonadales OU Belongs to the peptidase S14 family - - - - - - - - - - - - CLP_protease,Mu-like_gpT k59_39711_1 1692244.A0A0K1RLR5_9CIRC 3.19e-35 128.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_24514_1 1114964.L485_07205 2.74e-103 316.0 COG0175@1|root,COG0175@2|Bacteria 2|Bacteria EH sulfate reduction - - - - - - - - - - - - PAPS_reduct k59_256482_1 1692242.A0A0K1RKZ2_9CIRC 4e-34 129.0 4QFEW@10239|Viruses,4QUKZ@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_107205_1 1385658.U5KPZ6_9VIRU 3.93e-203 582.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_107205_3 1385658.U5KNR1_9VIRU 1.14e-46 164.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_198513_3 91604.ID47_02985 5.16e-122 372.0 COG0507@1|root,COG0507@2|Bacteria,1R1AT@1224|Proteobacteria,2U1ZX@28211|Alphaproteobacteria 28211|Alphaproteobacteria L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD - - - - - - - - - - - - Terminase_6 k59_198513_5 913865.DOT_1568 1.47e-111 332.0 28MC2@1|root,2ZAQD@2|Bacteria,1VSEU@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - k59_198513_10 1396141.BATP01000029_gene2258 4.39e-48 166.0 2E0FE@1|root,32W1M@2|Bacteria,46TEN@74201|Verrucomicrobia,2IVPU@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Domain of unknown function (DUF932) - - - - - - - - - - - - DUF932 k59_198513_16 592316.Pat9b_2142 3.16e-42 142.0 COG4570@1|root,COG4570@2|Bacteria,1RH5J@1224|Proteobacteria,1S7I6@1236|Gammaproteobacteria 1236|Gammaproteobacteria L endodeoxyribonuclease RusA - - - - - - - - - - - - RusA k59_16261_3 1385658.U5KPZ6_9VIRU 9.98e-130 395.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_256668_1 1498011.A0A096XUU5_9CAUD 2.69e-23 99.4 4QAUT@10239|Viruses,4QQ7X@28883|Caudovirales,4QNET@10744|Podoviridae 10744|Podoviridae S DNA ligase (ATP) activity - - - - - - - - - - - - - k59_256668_2 1498011.A0A096XUX6_9CAUD 2.58e-208 603.0 4QCZC@10239|Viruses,4QRH3@28883|Caudovirales 28883|Caudovirales S Bacterial DNA polymerase III alpha subunit - - - - - - - - - - - - - k59_198641_2 1500893.JQNB01000001_gene3326 1.34e-23 99.4 COG0258@1|root,COG0258@2|Bacteria,1MYSI@1224|Proteobacteria,1SQ55@1236|Gammaproteobacteria 1236|Gammaproteobacteria L 5'-3' exonuclease, N-terminal resolvase-like domain - - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc_N k59_265008_8 2003327.CAPSD_BPCHP 2.92e-51 190.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_41136_2 1449350.OCH239_10860 2.72e-15 71.6 2CJ1K@1|root,2Z9CA@2|Bacteria,1R519@1224|Proteobacteria,2U28U@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_124933_1 1000565.METUNv1_03733 1.13e-18 89.0 COG1475@1|root,COG1475@2|Bacteria,1R3Q6@1224|Proteobacteria,2VRKG@28216|Betaproteobacteria,2KXDD@206389|Rhodocyclales 206389|Rhodocyclales K ParB-like nuclease domain - - - - - - - - - - - - ParBc k59_240925_1 145579.CAPSD_BPPHM 4.17e-15 80.1 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_124936_1 1234888.K0A2J2_9VIRU 8.19e-54 185.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_75128_1 1211814.CAPG01000097_gene4378 1.25e-06 57.8 COG5412@1|root,COG5412@2|Bacteria,1U9S8@1239|Firmicutes,4IJYV@91061|Bacilli,1ZEP9@1386|Bacillus 91061|Bacilli S phage tail tape measure protein - - - - - - - - - - - - - k59_66782_1 202956.BBNL01000066_gene214 1.69e-30 129.0 2D784@1|root,32TNH@2|Bacteria,1N098@1224|Proteobacteria,1SDM3@1236|Gammaproteobacteria,3NNDQ@468|Moraxellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_75130_1 1453501.JELR01000001_gene2555 4.86e-12 64.7 COG0270@1|root,COG0270@2|Bacteria,1MV9D@1224|Proteobacteria,1RPD1@1236|Gammaproteobacteria,4667K@72275|Alteromonadaceae 1236|Gammaproteobacteria L C-5 cytosine-specific DNA methylase dcm - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_75130_2 153948.NAL212_2341 7.31e-09 54.7 2E7GT@1|root,331ZH@2|Bacteria,1NAHD@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_141424_1 1477404.A0A023NH97_9CAUD 9.87e-147 449.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QNBK@10744|Podoviridae 10744|Podoviridae S Ribonucleotide reductase, barrel domain - - - - - - - - - - - - - k59_16969_1 314230.DSM3645_28792 3.13e-06 55.8 COG1357@1|root,COG1357@2|Bacteria,2J2VS@203682|Planctomycetes 203682|Planctomycetes S PFAM Pentapeptide repeats (8 copies) - - - - - - - - - - - - - k59_116564_1 1203568.HMPREF1484_01995 2.13e-48 168.0 COG0863@1|root,COG0863@2|Bacteria,2GP2V@201174|Actinobacteria 201174|Actinobacteria KL DNA methylase - - - - - - - - - - - - N6_N4_Mtase,ParBc k59_249241_1 105154.Q9MBU6_9VIRU 9.51e-120 366.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_25429_1 1234888.K0A2J2_9VIRU 6.16e-38 141.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_216120_1 186617.M9MJB7_9VIRU 0.000307 47.0 4QB1C@10239|Viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_191188_3 2003327.CAPSD_BPCHP 1.4e-90 296.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_67575_1 1266925.JHVX01000006_gene2073 1.39e-06 53.9 COG5449@1|root,COG5449@2|Bacteria,1PUJN@1224|Proteobacteria,2VWIA@28216|Betaproteobacteria,374H6@32003|Nitrosomonadales 28216|Betaproteobacteria S Phage conserved hypothetical protein BR0599 - - - - - - - - - - - - DUF2163,Phage_BR0599 k59_191735_2 1406780.U5PW40_9CAUD 3.82e-69 219.0 4QEMD@10239|Viruses,4R0JN@35237|dsDNA viruses no RNA stage,4QUGF@28883|Caudovirales,4QNXF@10744|Podoviridae 10744|Podoviridae S AAA domain - - - - - - - - - - - - - k59_191735_3 1563661.A0A097PAN0_9CAUD 2.82e-47 174.0 4QGA5@10239|Viruses,4QT9N@28883|Caudovirales,4QP47@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_76047_1 222449.REP_BGYMJ 2.55e-05 53.9 4QB6C@10239|Viruses,4QUKM@29258|ssDNA viruses 10239|Viruses J Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_125875_1 1096546.WYO_0656 5.93e-22 92.4 COG1051@1|root,COG1051@2|Bacteria 2|Bacteria F GDP-mannose mannosyl hydrolase activity - - - - - - - - - - - - NUDIX k59_167281_2 296591.Bpro_1925 1.79e-08 55.5 2EBI6@1|root,335IM@2|Bacteria,1NATB@1224|Proteobacteria,2W4GZ@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_92592_3 388399.SSE37_25343 5.55e-36 140.0 COG0616@1|root,COG0616@2|Bacteria,1QGPW@1224|Proteobacteria,2U2TT@28211|Alphaproteobacteria 28211|Alphaproteobacteria OU COG0616 periplasmic serine proteases (ClpP class) - - - - - - - - - - - - Peptidase_S49 k59_67666_1 1184251.TCELL_0178 6.46e-09 60.1 COG1091@1|root,arCOG01367@2157|Archaea,2XPWF@28889|Crenarchaeota 28889|Crenarchaeota M DTDP-4-dehydrorhamnose reductase rfbD - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind k59_17616_3 1524882.A0A076GD16_9CAUD 2.99e-54 189.0 4QGIT@10239|Viruses,4QQNT@28883|Caudovirales,4QMVR@10699|Siphoviridae 10699|Siphoviridae S viral capsid - - - - - - - - - - - - - k59_134157_1 305900.GV64_08545 4.48e-21 96.7 COG0433@1|root,COG0433@2|Bacteria,1QTVP@1224|Proteobacteria,1T1IQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Zonular occludens toxin (Zot) - - - ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko02042 - - - Zot k59_93150_1 1379725.S5TMY9_9CIRC 4.65e-57 187.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_143326_3 2003327.CAPSD_BPCHP 4.44e-26 114.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_168076_1 1197951.I6S6K3_9CAUD 2.14e-09 64.7 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales 28883|Caudovirales S N-acetylmuramoyl-L-alanine amidase activity - - - - - - - - - - - - - k59_27247_1 32057.KB217480_gene8161 2.75e-15 85.5 COG0358@1|root,COG1643@1|root,COG0358@2|Bacteria,COG1643@2|Bacteria,1G3XT@1117|Cyanobacteria,1HNJB@1161|Nostocales 1117|Cyanobacteria L Atp-dependent helicase - - - - - - - - - - - - zf-CHC2 k59_68268_3 40631.O64366_BPN15 1.76e-77 246.0 4QAIJ@10239|Viruses,4QVZ9@35237|dsDNA viruses no RNA stage,4QPXI@28883|Caudovirales,4QM02@10699|Siphoviridae 10699|Siphoviridae S C-5 cytosine-specific DNA methylase - - - - - - - - - - - - - k59_226054_5 1029824.AFID01000003_gene199 2.45e-16 80.9 COG0566@1|root,COG0566@2|Bacteria,2GM1A@201174|Actinobacteria,1W7E6@1268|Micrococcaceae 201174|Actinobacteria J rRNA methyltransferase trmH - 2.1.1.34 ko:K00556 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase k59_226054_6 1289387.AUKW01000005_gene1653 3.51e-13 66.6 2CC86@1|root,3043Z@2|Bacteria,2IRMY@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_226054_10 1440774.Y900_025690 9.31e-38 138.0 COG3000@1|root,COG3000@2|Bacteria,2HR3N@201174|Actinobacteria,234PY@1762|Mycobacteriaceae 201174|Actinobacteria I Fatty acid hydroxylase - - - - - - - - - - - - FA_hydroxylase k59_226054_14 1556290.A0A0A0RQE6_9CAUD 1.66e-69 219.0 4QAUS@10239|Viruses,4QQ2S@28883|Caudovirales,4QKRA@10699|Siphoviridae 10699|Siphoviridae S flavin adenine dinucleotide binding - - - - - - - - - - - - - k59_134930_1 105154.Q9MBU6_9VIRU 7.72e-115 348.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_134930_7 1385658.U5KNR1_9VIRU 3.95e-78 248.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_134930_9 105154.Q9MBU6_9VIRU 2.08e-71 236.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_184384_1 490913.C4NTD1_9CAUD 8.86e-98 310.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_52043_1 1327977.S0A018_9CAUD 1.09e-16 84.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QNBD@10744|Podoviridae 10744|Podoviridae S outer membrane - - - - - - - - - - - - - k59_250562_1 1234888.K0A2J2_9VIRU 2.31e-44 159.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_185198_12 861360.AARI_03880 9.09e-10 68.9 COG5519@1|root,COG5519@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - PriCT_1,Prim-Pol k59_185198_16 234267.Acid_1347 6.96e-23 112.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,3Y3X3@57723|Acidobacteria 57723|Acidobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_185198_21 100226.SCO5064 0.000132 53.5 COG0553@1|root,COG0553@2|Bacteria,2GISC@201174|Actinobacteria 201174|Actinobacteria L helicase - - - - - - - - - - - - HHH_5,Helicase_C,SNF2_N k59_28320_4 398527.Bphyt_6642 5.68e-33 125.0 COG3409@1|root,COG3409@2|Bacteria,1R4RS@1224|Proteobacteria,2VTC5@28216|Betaproteobacteria,1K80T@119060|Burkholderiaceae 28216|Betaproteobacteria M CHAP domain - - - - - - - - - - - - CHAP k59_234595_1 761193.Runsl_4413 1.21e-05 50.1 COG0338@1|root,COG0338@2|Bacteria,4NRXP@976|Bacteroidetes 976|Bacteroidetes L DNA N-6-adenine-methyltransferase (Dam) - - - - - - - - - - - - Dam k59_77759_2 318586.Pden_3738 8.18e-05 53.1 2CHRY@1|root,30Z9E@2|Bacteria,1RGQK@1224|Proteobacteria,2U9J0@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - RecT k59_3429_1 102129.Lepto7375DRAFT_7444 1.14e-51 175.0 COG0270@1|root,COG0270@2|Bacteria 2|Bacteria L DNA (cytosine-5-)-methyltransferase activity - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_185298_2 742725.HMPREF9450_02123 1.34e-52 197.0 COG1196@1|root,COG1196@2|Bacteria,4NMBI@976|Bacteroidetes,2FR6N@200643|Bacteroidia 976|Bacteroidetes D nuclear chromosome segregation - - - - - - - - - - - - - k59_177021_1 1385658.U5KPZ6_9VIRU 1.42e-59 204.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_177021_5 1609634.A0A0C5AFV4_9VIRU 1.89e-35 140.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_19068_1 1692249.A0A0K1RLN8_9CIRC 1.8e-22 97.4 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_169210_2 640081.Dsui_1287 6e-14 75.1 COG1664@1|root,COG2911@1|root,COG3210@1|root,COG4386@1|root,COG1664@2|Bacteria,COG2911@2|Bacteria,COG3210@2|Bacteria,COG4386@2|Bacteria,1R4VM@1224|Proteobacteria,2VPC1@28216|Betaproteobacteria,2KWIJ@206389|Rhodocyclales 206389|Rhodocyclales U domain, Protein - - - ko:K12287 - - - - ko00000,ko02044 - - - - k59_227027_1 1609634.A0A0C5AFV4_9VIRU 3.07e-91 289.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_111076_1 186617.M9M8L2_9VIRU 9.94e-35 134.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_129351_2 1173762.S4TRN6_9CAUD 1.04e-91 288.0 4QBMV@10239|Viruses,4QUU6@35237|dsDNA viruses no RNA stage,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_170504_1 1385658.U5KPZ6_9VIRU 4.7e-91 284.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_112471_1 1089111.G8I7P9_9CAUD 2.5e-89 280.0 4QGKW@10239|Viruses,4QX43@35237|dsDNA viruses no RNA stage,4QPM6@28883|Caudovirales,4QM5T@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_129353_1 742740.HMPREF9474_02260 2.33e-35 134.0 28K55@1|root,2Z9TX@2|Bacteria,1V0P7@1239|Firmicutes,24DCX@186801|Clostridia,220T0@1506553|Lachnoclostridium 186801|Clostridia S Siphovirus ReqiPepy6 Gp37-like protein - - - - - - - - - - - - Sipho_Gp37 k59_46011_1 2003327.CAPSD_BPCHP 4.35e-21 96.3 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_221071_1 272568.GDI3673 1.97e-35 132.0 2DVPY@1|root,33WQ8@2|Bacteria,1N9VQ@1224|Proteobacteria,2UIC5@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_170657_2 1122609.AUGT01000008_gene2868 1.79e-23 108.0 COG0366@1|root,COG0515@1|root,COG2133@1|root,COG3227@1|root,COG4733@1|root,COG0366@2|Bacteria,COG0515@2|Bacteria,COG2133@2|Bacteria,COG3227@2|Bacteria,COG4733@2|Bacteria 2|Bacteria S cellulase activity - - 3.2.1.3 ko:K01178,ko:K14645,ko:K18546 ko00500,ko01100,ko02024,map00500,map01100,map02024 - R01790,R01791,R06199 - ko00000,ko00001,ko01000,ko01002,ko03110 - GH15 - Alpha-amylase,GSDH,He_PIG,PKD,Pro_Al_protease,SLH,Trypsin,fn3 k59_235715_1 1385658.U5KPZ6_9VIRU 9.59e-189 541.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_235715_2 105154.Q9MBU3_9VIRU 3.23e-08 60.5 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_261618_1 1609634.A0A0C5AFV4_9VIRU 4.81e-53 188.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_261618_3 1385658.U5KNR1_9VIRU 2.4e-15 79.3 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_137332_2 1609634.A0A0C5AFV4_9VIRU 3.08e-80 257.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_12265_3 913183.E5RV06_9CAUD 4.94e-38 134.0 4QASP@10239|Viruses,4QVR8@35237|dsDNA viruses no RNA stage,4QR4Z@28883|Caudovirales,4QNQ0@10744|Podoviridae 10744|Podoviridae S deoxyribonuclease IV (phage-T4-induced) activity - - - - - - - - - - - - - k59_195314_2 213777.R9R1C7_9CAUD 8.25e-06 51.2 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales,4QKM7@10699|Siphoviridae 10699|Siphoviridae S HNH endonuclease - - - - - - - - - - - - - k59_262562_2 105154.Q9MBU3_9VIRU 4.52e-09 60.8 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_62468_2 1379722.S5SY31_9CIRC 1.32e-10 61.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_79726_2 1123242.JH636435_gene3075 1e-23 99.8 COG0568@1|root,COG0568@2|Bacteria,2J2AT@203682|Planctomycetes 203682|Planctomycetes K Sigma-70 factor, region 1.1 - - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 k59_104638_1 1380894.S5TR92_9CIRC 1.5e-15 80.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_236593_1 1161935.H9D1E7_9CAUD 1.86e-28 115.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_121963_2 105154.Q9MBU6_9VIRU 2.3e-106 326.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_187958_1 414684.RC1_1120 5.3e-09 55.8 COG5005@1|root,COG5005@2|Bacteria,1N6UC@1224|Proteobacteria,2VCJG@28211|Alphaproteobacteria,2JUDS@204441|Rhodospirillales 204441|Rhodospirillales S COG5005 Mu-like prophage protein gpG - - - - - - - - - - - - Phage_tail_S k59_204604_1 1609634.A0A0C5AFV4_9VIRU 7.58e-44 160.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_262575_1 279238.Saro_2997 9.52e-55 188.0 2C8Q6@1|root,2Z882@2|Bacteria,1PY18@1224|Proteobacteria 1224|Proteobacteria S Phage stabilisation protein - - - - - - - - - - - - Phage_stabilise k59_79740_1 1692256.A0A0K1RL85_9CIRC 1.15e-14 74.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_6189_1 1692252.A0A0K1RL35_9CIRC 1.74e-48 165.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_138353_2 76869.PputGB1_1760 1.59e-44 165.0 28IJ1@1|root,2Z8K0@2|Bacteria,1R5PC@1224|Proteobacteria,1S1ER@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_222242_1 999413.HMPREF1094_02025 3.53e-78 250.0 COG0553@1|root,COG0553@2|Bacteria,1TP2C@1239|Firmicutes 1239|Firmicutes L DEAD-like helicases superfamily - - - - - - - - - - - - Helicase_C,N6_N4_Mtase,SNF2_N k59_236598_2 1609634.A0A0C5AFV4_9VIRU 2.47e-220 627.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_245033_1 1121430.JMLG01000021_gene1374 1.94e-12 72.4 COG4967@1|root,COG4967@2|Bacteria,1VKH2@1239|Firmicutes,24UHG@186801|Clostridia 186801|Clostridia NU type IV pilus modification protein PilV - - - - - - - - - - - - N_methyl k59_87190_1 1088721.NSU_0765 1.36e-14 70.1 2ED07@1|root,336X6@2|Bacteria,1N6RV@1224|Proteobacteria,2UHR8@28211|Alphaproteobacteria,2K6QR@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - k59_87190_2 1122135.KB893135_gene602 1.59e-67 216.0 28HXV@1|root,2Z83C@2|Bacteria,1PJBP@1224|Proteobacteria,2U8DN@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_179400_1 1692252.A0A0K1RL35_9CIRC 3.43e-61 200.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_179400_3 1618248.A0A0C5IB82_9CIRC 2.23e-27 108.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_223330_1 679201.HMPREF9334_00465 5.59e-05 46.2 2E3FM@1|root,32YEF@2|Bacteria 2|Bacteria S VRR-NUC domain - - - - - - - - - - - - VRR_NUC k59_80620_2 1234888.K0A2J2_9VIRU 1.89e-161 472.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_172790_1 1385658.U5KPZ6_9VIRU 2.47e-70 229.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_245918_1 1380394.JADL01000006_gene5256 6.13e-12 69.7 2913K@1|root,2ZNR0@2|Bacteria,1P84Q@1224|Proteobacteria,2UX38@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_139503_2 1234888.K0A2J2_9VIRU 2.9e-68 223.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_31815_2 1122599.AUGR01000024_gene1352 2.24e-24 99.4 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria,1XJHS@135619|Oceanospirillales 135619|Oceanospirillales L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_22060_1 1234888.K0A2J2_9VIRU 3.3e-22 97.1 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_223335_2 1217710.F969_00036 1.26e-103 320.0 COG5565@1|root,COG5565@2|Bacteria,1R6R3@1224|Proteobacteria,1RY0J@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C k59_172793_1 1096546.WYO_0201 7.14e-122 377.0 28P6A@1|root,2ZC10@2|Bacteria,1RBZE@1224|Proteobacteria,2UQEG@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_13994_1 648250.CAPSD_JDNVP 4.68e-05 53.9 4QEBH@10239|Viruses,4QUMC@29258|ssDNA viruses 10239|Viruses S Capsid protein VP4 - - - - - - - - - - - - - k59_13994_2 4792.ETI31775 2.25e-65 224.0 2C7RP@1|root,2SPXE@2759|Eukaryota 2759|Eukaryota - - - - - - - - - - - - - - - k59_139640_2 1692244.A0A0K1RLR5_9CIRC 2.2e-39 147.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_223438_1 1465639.A0A060BGU7_9CAUD 1.35e-14 72.8 4QENJ@10239|Viruses,4QWTV@35237|dsDNA viruses no RNA stage,4QPGY@28883|Caudovirales 28883|Caudovirales S methyltransferase activity - - - - - - - - - - - - - k59_22184_1 348824.LPU83_2108 9.18e-05 52.8 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,4B72Y@82115|Rhizobiaceae 28211|Alphaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - CHASE4,EAL,GGDEF,HAMP k59_237503_1 926566.Terro_1145 1.03e-16 87.8 COG3598@1|root,COG3598@2|Bacteria 2|Bacteria L Psort location Cytoplasmic, score - - - ko:K06919 - - - - ko00000 - - - AAA_25,DUF3991,Prim-Pol,Toprim_2 k59_212772_1 717785.HYPMC_4253 3.86e-11 68.9 COG5281@1|root,COG5281@2|Bacteria,1MX2R@1224|Proteobacteria,2U3WK@28211|Alphaproteobacteria 28211|Alphaproteobacteria D tape measure protein - - - - - - - - - - - - - k59_31928_1 2003327.CAPSD_BPCHP 5.59e-62 209.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_14081_1 1173762.S4TRT2_9CAUD 4e-32 122.0 4QF0B@10239|Viruses,4QX8P@35237|dsDNA viruses no RNA stage,4QSJT@28883|Caudovirales,4QNNK@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_14081_2 1173762.S4TNW6_9CAUD 3.97e-92 288.0 4QEFX@10239|Viruses,4QYYG@35237|dsDNA viruses no RNA stage,4QRRV@28883|Caudovirales,4QNTK@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_115850_2 665956.HMPREF1032_00640 2.95e-37 139.0 2A0KC@1|root,2ZGJK@2|Bacteria,1V2JS@1239|Firmicutes,24H6R@186801|Clostridia,3WNJK@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_140533_1 1121935.AQXX01000130_gene2454 1.94e-47 171.0 COG0419@1|root,COG0419@2|Bacteria,1R4K4@1224|Proteobacteria,1SN42@1236|Gammaproteobacteria 1236|Gammaproteobacteria L AAA domain - - - - - - - - - - - - AAA_23 k59_246712_1 1123072.AUDH01000029_gene1059 9.27e-10 65.9 COG4677@1|root,COG5434@1|root,COG4677@2|Bacteria,COG5434@2|Bacteria,1R7M4@1224|Proteobacteria,2U4CX@28211|Alphaproteobacteria,2JZM9@204441|Rhodospirillales 204441|Rhodospirillales M Pectate lyase superfamily protein - - - - - - - - - - - - Pectate_lyase_3 k59_106505_4 1489678.RDMS_01495 5.59e-25 104.0 COG0739@1|root,COG0739@2|Bacteria,1WMXC@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus M Peptidase family M23 - - - - - - - - - - - - Peptidase_M23 k59_124245_1 1692244.A0A0K1RLR5_9CIRC 4.96e-63 204.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_124245_3 1788439.A0A190WHD0_9CIRC 1.99e-05 48.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_190565_3 105154.Q9MBU6_9VIRU 5.78e-169 497.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_190565_4 105154.Q9MBU3_9VIRU 1.38e-10 65.1 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_23201_1 1220601.L7TJ71_9CAUD 2.16e-25 109.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales 28883|Caudovirales S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_90112_1 717772.THIAE_05795 4.7e-18 89.4 COG0358@1|root,COG5545@1|root,COG0358@2|Bacteria,COG5545@2|Bacteria,1MVGK@1224|Proteobacteria,1SAWT@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Virulence-associated protein E - - - ko:K06919 - - - - ko00000 - - - VirE k59_107767_1 1400524.KL370779_gene620 1.65e-77 256.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TR1I@28211|Alphaproteobacteria,4BP68@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria EH TIGRFAM acetolactate synthase, large subunit, biosynthetic type - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k59_90120_1 1211817.CCAT010000049_gene2439 2.67e-32 127.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,36M8D@31979|Clostridiaceae 186801|Clostridia L SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,SNF2_N k59_265117_1 1449126.JQKL01000019_gene3225 5.34e-46 155.0 COG0518@1|root,COG0518@2|Bacteria,1UAH0@1239|Firmicutes,24DR4@186801|Clostridia 186801|Clostridia F PFAM Glutamine amidotransferase class-I - - - - - - - - - - - - GATase k59_215596_1 460265.Mnod_6992 4.09e-75 240.0 COG0270@1|root,COG0270@2|Bacteria,1MV9H@1224|Proteobacteria,2TTZG@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family dcm - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase,HTH_3,HTH_31 k59_66160_6 244582.JQAK01000008_gene619 2.18e-41 162.0 COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,2TQWC@28211|Alphaproteobacteria,47EZE@766|Rickettsiales 766|Rickettsiales L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity recD2 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 k59_66160_7 1206556.I7KQQ0_9CAUD 4.16e-11 67.8 4QG29@10239|Viruses,4QZ7B@35237|dsDNA viruses no RNA stage,4QT35@28883|Caudovirales,4QNCJ@10744|Podoviridae 10744|Podoviridae S ATP binding - - - - - - - - - - - - - k59_91038_3 313628.LNTAR_21400 5.43e-13 79.7 COG3291@1|root,COG4447@1|root,COG3291@2|Bacteria,COG4447@2|Bacteria 2|Bacteria S cellulose binding - - 3.2.1.4,3.2.1.73 ko:K01179,ko:K01216,ko:K21449 ko00500,ko01100,map00500,map01100 - R06200,R11307,R11308 - ko00000,ko00001,ko01000,ko02000 1.B.40.2 GH5,GH9 - CBM_3,F5_F8_type_C,PKD,fn3 k59_91058_2 1051675.G0YQI9_9CAUD 3.76e-61 198.0 4QF0B@10239|Viruses,4QX8P@35237|dsDNA viruses no RNA stage,4QSJT@28883|Caudovirales,4QNNK@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_91058_3 1051675.G0YQJ0_9CAUD 7.17e-289 800.0 4QEFX@10239|Viruses,4QYYG@35237|dsDNA viruses no RNA stage,4QRRV@28883|Caudovirales,4QNTK@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_91058_4 1051675.G0YQJ1_9CAUD 5.51e-66 211.0 4QGM6@10239|Viruses,4QYNV@35237|dsDNA viruses no RNA stage,4QRH4@28883|Caudovirales,4QP0P@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_91088_1 313596.RB2501_01430 4.05e-73 226.0 COG2887@1|root,COG2887@2|Bacteria,4P6Q6@976|Bacteroidetes 976|Bacteroidetes L Belongs to the helicase family. UvrD subfamily - - - - - - - - - - - - - k59_91134_2 1051675.G0YQC3_9CAUD 1.23e-52 181.0 4QBMV@10239|Viruses,4QUU6@35237|dsDNA viruses no RNA stage,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_91147_1 391037.Sare_2186 1.4e-06 55.1 2CDGZ@1|root,34CGM@2|Bacteria,2GYBU@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_91190_4 414996.IL38_06945 3.52e-14 72.4 2DN54@1|root,32VJI@2|Bacteria 2|Bacteria L Recombination endonuclease VII - - - - - - - - - - - - Endonuclease_7 k59_132770_4 1234888.K0A2R8_9VIRU 9.16e-44 160.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_223993_1 4920.XP_004200703.1 7.91e-29 124.0 COG5108@1|root,KOG1038@2759|Eukaryota,38EAY@33154|Opisthokonta,3NU1C@4751|Fungi,3QN4S@4890|Ascomycota,3RS68@4891|Saccharomycetes,479W3@766764|Debaryomycetaceae 4751|Fungi KL DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates - - 2.7.7.6 ko:K10908 - - - - ko00000,ko01000,ko03029 - - - RNA_pol,RPOL_N k59_91297_1 1234888.K0A2J2_9VIRU 3.22e-25 106.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_24974_1 1692244.A0A0K1RLR5_9CIRC 1.97e-65 210.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_116198_2 1145276.T479_03280 9.03e-17 82.4 COG1861@1|root,COG1861@2|Bacteria,1U4YD@1239|Firmicutes,4HG5W@91061|Bacilli,3J061@400634|Lysinibacillus 91061|Bacilli M Cytidylyltransferase - - - ko:K07257 - - - - ko00000 - - - CTP_transf_3 k59_107900_1 747.DR93_1216 1.14e-17 79.3 2AMM7@1|root,31CH8@2|Bacteria,1RJ8Y@1224|Proteobacteria,1SAP1@1236|Gammaproteobacteria,1Y8V6@135625|Pasteurellales 135625|Pasteurellales L Pyrimidine dimer DNA glycosylase denV - 3.1.25.1 ko:K01161 - - - - ko00000,ko01000 - - - Pyr_excise k59_107900_2 1121864.OMO_01118 4.97e-08 64.3 COG0739@1|root,COG3942@1|root,COG0739@2|Bacteria,COG3942@2|Bacteria,1UNUC@1239|Firmicutes,4IUPT@91061|Bacilli,4B60K@81852|Enterococcaceae 91061|Bacilli M Peptidase family M23 - - - - - - - - - - - - CHAP,Peptidase_M23 k59_99580_1 1101189.AQUO01000001_gene1436 1.27e-17 86.3 28MC2@1|root,2ZAQD@2|Bacteria,1R5I0@1224|Proteobacteria,2TUSQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_158259_1 1477404.A0A023NFY0_9CAUD 1.48e-227 646.0 4QGA5@10239|Viruses,4QURD@35237|dsDNA viruses no RNA stage,4QT9N@28883|Caudovirales,4QP47@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_216577_1 520999.PROVALCAL_02561 1.9e-12 74.3 2DBAD@1|root,2Z82M@2|Bacteria,1QWBK@1224|Proteobacteria,1T363@1236|Gammaproteobacteria,3Z9UV@586|Providencia 1236|Gammaproteobacteria S Bacteriophage replication protein O - - - - - - - - - - - - Phage_rep_O k59_125429_1 1618260.A0A0C5I2C5_9CIRC 4.49e-53 174.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_117018_1 155515.JP36_07485 3.71e-34 131.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,1TKGR@1236|Gammaproteobacteria,1Y7SY@135625|Pasteurellales 135625|Pasteurellales S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_117018_2 1054213.HMPREF9946_02222 6.99e-08 53.9 COG3740@1|root,COG3740@2|Bacteria,1QVIJ@1224|Proteobacteria,2TVIM@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Phage capsid family - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_75603_1 105154.Q9MBU6_9VIRU 4.77e-72 233.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_92174_2 1379717.S5SY19_9CIRC 5.87e-15 78.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_191489_2 1219076.N646_4286 3.71e-42 141.0 2DN9C@1|root,32W8M@2|Bacteria,1N2J0@1224|Proteobacteria,1SBVC@1236|Gammaproteobacteria,1XZ5A@135623|Vibrionales 135623|Vibrionales S Phage related protein - - - - - - - - - - - - DUF3693 k59_42411_1 1123253.AUBD01000001_gene1479 1.06e-10 63.9 COG0616@1|root,COG0616@2|Bacteria,1QGPW@1224|Proteobacteria,1RZZW@1236|Gammaproteobacteria,1X588@135614|Xanthomonadales 135614|Xanthomonadales OU Peptidase family S49 - - - - - - - - - - - - Peptidase_S49 k59_42411_2 1224136.AMFN01000024_gene42 1.61e-45 166.0 COG4653@1|root,COG4653@2|Bacteria,1Q3BS@1224|Proteobacteria,1S17W@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage capsid family - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_142004_3 1609634.A0A0C5AFV4_9VIRU 1.6e-64 225.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_25903_1 1089552.KI911559_gene3672 2.3e-32 132.0 COG2755@1|root,COG2931@1|root,COG3420@1|root,COG4254@1|root,COG2755@2|Bacteria,COG2931@2|Bacteria,COG3420@2|Bacteria,COG4254@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,2JQMP@204441|Rhodospirillales 204441|Rhodospirillales OQ COG2931 RTX toxins and related Ca2 -binding proteins - - - - - - - - - - - - HemolysinCabind k59_166824_1 1618260.A0A0C5I2C5_9CIRC 5.83e-28 110.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_150263_3 264730.PSPPH_2788 3.79e-74 239.0 COG4128@1|root,COG4128@2|Bacteria,1N0I7@1224|Proteobacteria,1SAH8@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Zonular occludens toxin (Zot) zot GO:0001906,GO:0006810,GO:0006996,GO:0007010,GO:0008150,GO:0009405,GO:0009987,GO:0016043,GO:0031640,GO:0035821,GO:0042044,GO:0042045,GO:0044364,GO:0044419,GO:0051179,GO:0051234,GO:0051704,GO:0070633,GO:0071840 - ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko02042 - - - Zot k59_249692_1 1618247.A0A0C5IMK7_9CIRC 3.66e-15 79.7 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_216685_2 869209.Tresu_2648 3.83e-09 53.9 2A6AJ@1|root,30V37@2|Bacteria,2J9E5@203691|Spirochaetes 203691|Spirochaetes S Protein of unknown function (DUF2997) - - - - - - - - - - - - DUF2997 k59_191490_3 1517681.HW45_19920 2.15e-21 92.8 2DMPB@1|root,32SV8@2|Bacteria,1NHUE@1224|Proteobacteria,1SIKI@1236|Gammaproteobacteria,1XY3E@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k59_183331_1 1545915.JROG01000003_gene1027 8.28e-18 96.7 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2TRJF@28211|Alphaproteobacteria,2K1KW@204457|Sphingomonadales 204457|Sphingomonadales L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_183331_4 1120971.AUCA01000037_gene2881 7.12e-15 72.4 2DP7B@1|root,330UW@2|Bacteria,1VMUH@1239|Firmicutes,4I26A@91061|Bacilli 91061|Bacilli S Domain of unknown function (DUF4406) - - - - - - - - - - - - DUF4406 k59_259348_1 1358423.N180_15810 1.22e-34 136.0 COG0358@1|root,COG0358@2|Bacteria,4NENT@976|Bacteroidetes,1IR9Y@117747|Sphingobacteriia 976|Bacteroidetes L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 k59_143309_4 1122599.AUGR01000001_gene288 1.19e-57 187.0 COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,1SQ0T@1236|Gammaproteobacteria 1236|Gammaproteobacteria L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_233776_1 1123487.KB892865_gene1410 6.88e-34 126.0 COG1793@1|root,COG1793@2|Bacteria,1MUW3@1224|Proteobacteria,2VI3P@28216|Betaproteobacteria,2KUKX@206389|Rhodocyclales 206389|Rhodocyclales L DNA ligase dnaL - 6.5.1.1,6.5.1.6,6.5.1.7 ko:K10747 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00381,R00382,R10822,R10823 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - DNA_ligase_A_M,DNA_ligase_OB_2 k59_151537_1 2003327.CAPSD_BPCHP 7.34e-17 88.2 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_184290_2 106648.BBLJ01000064_gene4101 4.79e-20 90.9 COG1961@1|root,COG1961@2|Bacteria,1R3XB@1224|Proteobacteria,1RSC2@1236|Gammaproteobacteria,3NNJ2@468|Moraxellaceae 1236|Gammaproteobacteria L Resolvase, N terminal domain - - - - - - - - - - - - Resolvase k59_184290_3 1394178.AWOO02000004_gene2491 0.000786 42.0 COG1426@1|root,COG1426@2|Bacteria,2I4Y1@201174|Actinobacteria,4EK9T@85012|Streptosporangiales 201174|Actinobacteria K Helix-turn-helix domain - - - - - - - - - - - - HTH_3,HTH_31,HTH_37 k59_159253_1 1385658.U5KPZ6_9VIRU 7.05e-23 103.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_93147_7 910964.GEAM_4248 3.15e-10 72.4 COG1196@1|root,COG1196@2|Bacteria,1MU81@1224|Proteobacteria,1RS6P@1236|Gammaproteobacteria 1236|Gammaproteobacteria D tail length tape measure - - - - - - - - - - - - TMP_2,Tape_meas_lam_C k59_18125_2 1123499.KB908021_gene946 2.05e-24 96.3 COG1694@1|root,COG1694@2|Bacteria,1NBT1@1224|Proteobacteria,2VXT8@28216|Betaproteobacteria,2KT7H@206351|Neisseriales 206351|Neisseriales S MazG nucleotide pyrophosphohydrolase domain - - - - - - - - - - - - MazG k59_84636_30 1191380.J7I4J7_9CAUD 4.88e-25 100.0 4QB0C@10239|Viruses,4QW7S@35237|dsDNA viruses no RNA stage,4QPK3@28883|Caudovirales,4QKQC@10699|Siphoviridae 10699|Siphoviridae S magnesium ion binding - - - - - - - - - - - - - k59_84636_33 1120963.KB894494_gene3673 3.14e-17 90.5 COG0467@1|root,COG3598@1|root,COG4983@1|root,COG0467@2|Bacteria,COG3598@2|Bacteria,COG4983@2|Bacteria 2|Bacteria L Phage plasmid primase, P4 family domain protein - - - ko:K06919 - - - - ko00000 - - - AAA_11,AAA_12,AAA_25,DUF3320,DUF4011,Prim-Pol k59_84636_34 67281.JNZZ01000024_gene4713 1.56e-79 270.0 COG0467@1|root,COG3378@1|root,COG0467@2|Bacteria,COG3378@2|Bacteria,2H1DT@201174|Actinobacteria 201174|Actinobacteria T Phage plasmid primase, P4 family - - - ko:K06919 - - - - ko00000 - - - D5_N,DUF3854,Pox_D5,PriCT_1,Prim-Pol k59_84636_35 270374.MELB17_09208 2.33e-80 277.0 COG0553@1|root,COG0553@2|Bacteria,1MV6M@1224|Proteobacteria,1SN4D@1236|Gammaproteobacteria 1236|Gammaproteobacteria KL SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,SNF2_N k59_84636_37 1005994.GTGU_01505 3.21e-34 142.0 COG0270@1|root,COG0338@1|root,COG0270@2|Bacteria,COG0338@2|Bacteria,1MV9H@1224|Proteobacteria,1RPSH@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase,MethyltransfD12 k59_84636_47 765698.Mesci_3835 2.31e-85 276.0 COG5323@1|root,COG5323@2|Bacteria,1R049@1224|Proteobacteria 1224|Proteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6 k59_93207_3 240302.BN982_00199 1.21e-15 79.3 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4H9YP@91061|Bacilli 91061|Bacilli L SNF2 family - - - - - - - - - - - - Helicase_C,SNF2_N k59_102631_1 1154860.SAG0136_11375 3.63e-14 74.3 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4H9YP@91061|Bacilli 91061|Bacilli L SNF2 family - - - - - - - - - - - - Helicase_C,SNF2_N k59_219604_3 517417.Cpar_0523 2.59e-18 96.7 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1FDI1@1090|Chlorobi 1090|Chlorobi L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_78019_1 268739.Nmlp_3709 3.25e-19 91.3 arCOG03499@1|root,arCOG04500@1|root,arCOG07554@1|root,arCOG10954@1|root,arCOG03499@2157|Archaea,arCOG04500@2157|Archaea,arCOG07554@2157|Archaea,arCOG10954@2157|Archaea,2XV12@28890|Euryarchaeota,23TP6@183963|Halobacteria 183963|Halobacteria L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone - - - - - - - - - - - - Glug k59_102717_1 1498172.A0A0F6N5L2_9CAUD 4.16e-05 48.5 4QFN3@10239|Viruses,4QQ4M@28883|Caudovirales,4QNXC@10744|Podoviridae 10744|Podoviridae S exonuclease activity - - - - - - - - - - - - - k59_28610_2 1505227.A0A076GAF9_9CAUD 1.35e-48 157.0 4QGQX@10239|Viruses,4QQ2D@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_44847_1 1692249.A0A0K1RLN8_9CIRC 9.27e-35 132.0 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_169520_1 580332.Slit_1947 4.66e-30 116.0 28KIJ@1|root,2ZA3S@2|Bacteria,1R4PD@1224|Proteobacteria,2VP07@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_169520_2 641147.HMPREF9021_02702 9.71e-17 80.1 COG1074@1|root,COG1074@2|Bacteria,1QUUZ@1224|Proteobacteria,2WI1S@28216|Betaproteobacteria 1224|Proteobacteria L PDDEXK-like domain of unknown function (DUF3799) - - - - - - - - - - - - DUF3799 k59_152971_3 926560.KE387029_gene76 1.69e-27 105.0 COG1694@1|root,COG1694@2|Bacteria 2|Bacteria FG Mazg nucleotide pyrophosphohydrolase - - - - - - - - - - - - MazG k59_152971_4 1120971.AUCA01000053_gene371 7.21e-76 241.0 COG0863@1|root,COG0863@2|Bacteria,1UZIN@1239|Firmicutes,4HU16@91061|Bacilli 91061|Bacilli L DNA methylase - - - - - - - - - - - - N6_N4_Mtase k59_111399_3 1609634.A0A0C5AFV4_9VIRU 9.19e-82 271.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_243460_2 1618248.A0A0C5IB82_9CIRC 1.87e-93 286.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_94146_1 1234888.K0A2J2_9VIRU 4.46e-30 121.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_177362_2 411460.RUMTOR_01326 6.9e-26 99.0 2EN82@1|root,33FVV@2|Bacteria,1VKRH@1239|Firmicutes,24V2G@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_128175_1 411460.RUMTOR_01342 5.58e-21 88.6 28NM4@1|root,2ZBMQ@2|Bacteria,1V1QD@1239|Firmicutes,24G1B@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_128175_3 411460.RUMTOR_01344 1.93e-20 84.3 2E2Y0@1|root,32XYV@2|Bacteria,1VD9S@1239|Firmicutes,24PK0@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_129681_17 1548905.A0A0A1IV41_9CAUD 7.69e-50 161.0 4QB7F@10239|Viruses,4QS2F@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_129681_18 462590.A9J4Z1_BPPYU 6.5e-186 540.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_129681_19 103807.Q9MBZ3_9CAUD 4.62e-37 130.0 4QHC8@10239|Viruses,4QZ9A@35237|dsDNA viruses no RNA stage,4QSRC@28883|Caudovirales,4QKFD@10662|Myoviridae 10662|Myoviridae S D-alanyl-D-alanine carboxypeptidase - - - - - - - - - - - - - k59_129681_20 279383.Q5DNA1_9CAUD 1.21e-22 90.1 4QGUU@10239|Viruses,4QX39@35237|dsDNA viruses no RNA stage,4QRVT@28883|Caudovirales,4QMJG@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_129681_22 1122132.AQYH01000008_gene2786 1.09e-10 59.7 2BRBV@1|root,32KAE@2|Bacteria,1PR6I@1224|Proteobacteria,2V3HJ@28211|Alphaproteobacteria,4BKMY@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_129681_24 1123501.KB902299_gene3817 1.04e-44 182.0 COG2304@1|root,COG2304@2|Bacteria,1QWI7@1224|Proteobacteria,2TY8F@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Putative phage tail protein - - - - - - - - - - - - Phage-tail_3,VWA k59_129681_25 1123487.KB892867_gene973 1.5e-12 73.6 COG5449@1|root,COG5449@2|Bacteria,1MXK2@1224|Proteobacteria,2VSPS@28216|Betaproteobacteria,2KZ3U@206389|Rhodocyclales 206389|Rhodocyclales S Phage conserved hypothetical protein BR0599 - - - - - - - - - - - - DUF2163,Phage_BR0599 k59_129681_28 1132026.I6NQT6_9CAUD 2.98e-20 97.8 4QEU0@10239|Viruses,4QTB3@28883|Caudovirales,4QM4I@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_129681_29 259536.Psyc_1030 2.6e-40 169.0 COG5281@1|root,COG5281@2|Bacteria,1MX2R@1224|Proteobacteria,1S3MM@1236|Gammaproteobacteria,3NSS7@468|Moraxellaceae 1236|Gammaproteobacteria D tape measure protein Z012_10445 - - - - - - - - - - - Phage_HK97_TLTM,Tape_meas_lam_C k59_129681_30 1548905.A0A0A1IV69_9CAUD 2.61e-41 141.0 4QF2R@10239|Viruses,4QPI5@28883|Caudovirales,4QMKW@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_129681_31 1548905.A0A0A1IVS4_9CAUD 7.89e-141 407.0 4QH9I@10239|Viruses,4QTW6@28883|Caudovirales,4QMZW@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_129681_36 1468411.X2KTX4_9CAUD 2.91e-05 50.1 4QFXT@10239|Viruses,4QRG1@28883|Caudovirales,4QM7W@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_129681_37 462590.A9J587_BPPYU 4.07e-158 450.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - GO:0005575,GO:0019012,GO:0019028,GO:0032991,GO:0044423,GO:0046806 - - - - - - - - - - - k59_129681_39 1548905.A0A0A1IX09_9CAUD 8.95e-127 379.0 4QC5Z@10239|Viruses,4QPGX@28883|Caudovirales,4QKMB@10699|Siphoviridae 10699|Siphoviridae S Phage Mu protein F like protein - GO:0005575,GO:0019012,GO:0019028,GO:0044423,GO:0046729 - - - - - - - - - - - k59_146423_2 1122201.AUAZ01000017_gene2948 8.83e-35 135.0 COG0507@1|root,COG0507@2|Bacteria,1QFB2@1224|Proteobacteria,1SE0Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria L AAA domain - - - - - - - - - - - - AAA_30,UvrD_C_2,Viral_helicase1 k59_12519_1 2754.EH55_13250 1.91e-08 65.5 COG0419@1|root,COG3064@1|root,COG3941@1|root,COG0419@2|Bacteria,COG3064@2|Bacteria,COG3941@2|Bacteria 2|Bacteria O tape measure - - 2.1.1.80,3.1.1.61 ko:K03529,ko:K13582,ko:K13924 ko02020,ko02030,ko04112,map02020,map02030,map04112 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035,ko03036 - - - AAA_15,AAA_21 k59_54789_1 1519464.HY22_09210 0.000177 47.4 COG0451@1|root,COG0451@2|Bacteria 2|Bacteria GM ADP-glyceromanno-heptose 6-epimerase activity - - 5.1.3.10,5.1.3.2 ko:K01784,ko:K12454 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984,R04266 RC00289,RC00528 ko00000,ko00001,ko00002,ko01000 - - - Epimerase k59_54789_2 316055.RPE_1511 2.65e-160 469.0 COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,2TRCN@28211|Alphaproteobacteria,3JTVF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - - - - - - - - - - CTP_transf_like,PfkB k59_161968_2 398578.Daci_2097 1.87e-39 150.0 COG4128@1|root,COG4128@2|Bacteria,1R51Y@1224|Proteobacteria,2VIPX@28216|Betaproteobacteria,4AFJF@80864|Comamonadaceae 28216|Betaproteobacteria S Zonular occludens toxin (Zot) - - - ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko02042 - - - Zot k59_161968_3 1000565.METUNv1_03730 9.59e-06 48.5 2DSGW@1|root,33G2M@2|Bacteria,1NKRQ@1224|Proteobacteria,2VYBE@28216|Betaproteobacteria 28216|Betaproteobacteria S Protein of unknown function (DUF2523) - - - - - - - - - - - - DUF2523 k59_161968_8 870187.Thini_0411 1.51e-33 133.0 2EP1Y@1|root,33GNT@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_30086_1 1121396.KB893070_gene1348 5.36e-40 145.0 COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,42QA8@68525|delta/epsilon subdivisions,2WJBW@28221|Deltaproteobacteria,2MIKF@213118|Desulfobacterales 28221|Deltaproteobacteria S PFAM ATPase associated with various cellular activities - - - - - - - - - - - - AAA_3,AAA_5 k59_228842_2 243365.CV_2132 8.72e-09 56.6 2BVH3@1|root,32QVR@2|Bacteria,1RM2I@1224|Proteobacteria,2VXPZ@28216|Betaproteobacteria,2KU20@206351|Neisseriales 206351|Neisseriales S Uncharacterized conserved protein (DUF2190) - - - - - - - - - - - - - k59_163327_1 1385658.U5KPZ6_9VIRU 5.83e-69 226.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_180438_5 1385658.U5KNR1_9VIRU 5.55e-62 207.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_163492_1 349521.HCH_05649 2.5e-24 111.0 COG4733@1|root,COG4733@2|Bacteria,1MXB4@1224|Proteobacteria,1RRUV@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Putative phage tail protein - - - - - - - - - - - - Phage-tail_3 k59_172830_1 399742.Ent638_2235 5.41e-26 109.0 COG4695@1|root,COG4695@2|Bacteria,1PFTD@1224|Proteobacteria,1RTWZ@1236|Gammaproteobacteria,3X3J3@547|Enterobacter 1236|Gammaproteobacteria S Portal protein - - - - - - - - - - - - - k59_212750_2 1166018.FAES_3984 1.3e-30 130.0 COG4653@1|root,COG4653@2|Bacteria,4NUPP@976|Bacteroidetes,47SEM@768503|Cytophagia 976|Bacteroidetes S Phage capsid family - - - - - - - - - - - - Phage_capsid k59_123124_1 1385658.U5KPZ6_9VIRU 1.38e-137 410.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_123124_6 1385658.U5KPZ6_9VIRU 4.94e-37 140.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_131349_2 1117943.SFHH103_00131 6.99e-112 347.0 COG5565@1|root,COG5565@2|Bacteria,1R6R3@1224|Proteobacteria,2U1P9@28211|Alphaproteobacteria,4BDQ9@82115|Rhizobiaceae 28211|Alphaproteobacteria S DNA packaging protein gp2 - - - - - - - - - - - - Terminase_6,Terminase_6C k59_263568_1 349161.Dred_1192 1.34e-73 239.0 COG0553@1|root,COG0553@2|Bacteria,1TP2C@1239|Firmicutes,24DVA@186801|Clostridia 186801|Clostridia L DEAD-like helicases superfamily - - - - - - - - - - - - Helicase_C,N6_N4_Mtase,SNF2_N k59_7407_1 186617.M9M8L2_9VIRU 6.41e-52 181.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_80646_1 754035.Mesau_00657 2.6e-61 197.0 COG1442@1|root,COG1442@2|Bacteria,1QH4S@1224|Proteobacteria,2U9KQ@28211|Alphaproteobacteria,43JIY@69277|Phyllobacteriaceae 28211|Alphaproteobacteria M glycosyl transferase family 8 - - - - - - - - - - - - - k59_80646_2 444860.E3SJ76_9CAUD 2.51e-135 394.0 4QCFA@10239|Viruses,4QUPF@35237|dsDNA viruses no RNA stage,4QQD7@28883|Caudovirales,4QIYX@10662|Myoviridae 10662|Myoviridae S coenzyme binding - - - - - - - - - - - - - k59_80646_3 335283.Neut_1465 4.19e-41 144.0 2DNB5@1|root,32WIW@2|Bacteria,1N0BM@1224|Proteobacteria 1224|Proteobacteria S Bacteriophage HK97-gp10, putative tail-component - - - - - - - - - - - - HK97-gp10_like k59_80646_4 160488.PP_1572 1.87e-33 120.0 2DM6W@1|root,32UGB@2|Bacteria,1N425@1224|Proteobacteria,1SGA9@1236|Gammaproteobacteria,1YYVU@136845|Pseudomonas putida group 1236|Gammaproteobacteria S Protein of unknown function (DUF3168) - - - - - - - - - - - - DUF3168 k59_80646_5 211586.SO_2956 4.55e-50 164.0 2DNA4@1|root,32WDI@2|Bacteria,1RH8K@1224|Proteobacteria,1S8YN@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage tail tube, TTP, lambda-like - - - - - - - - - - - - Phage_TTP_11 k59_80646_8 157783.LK03_13420 5.14e-12 67.4 COG1196@1|root,COG2911@1|root,COG1196@2|Bacteria,COG2911@2|Bacteria,1QU6S@1224|Proteobacteria,1S7WY@1236|Gammaproteobacteria 1236|Gammaproteobacteria D tail tape measure protein - - - - - - - - - - - - SLT,Tape_meas_lam_C k59_56361_2 1327981.S0A1N4_9CAUD 3.69e-31 121.0 4QFGZ@10239|Viruses,4QY9R@35237|dsDNA viruses no RNA stage,4QPY9@28883|Caudovirales,4QMRF@10699|Siphoviridae 10699|Siphoviridae S Phage terminase large subunit - - - - - - - - - - - - - k59_163497_1 1123277.KB893184_gene4032 7.75e-18 92.4 COG0467@1|root,COG0467@2|Bacteria,4NIAQ@976|Bacteroidetes 976|Bacteroidetes T Psort location Cytoplasmic, score 8.96 - - - - - - - - - - - - AAA_25 k59_156993_2 105154.Q9MBU3_9VIRU 6.57e-07 57.0 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_156993_3 1385658.U5KPZ6_9VIRU 5.61e-201 577.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_156993_6 1986029.Q9MBM3_9VIRU 1.54e-65 216.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_132341_1 1795992.A0A140CTS6_9CIRC 1.9e-50 169.0 4QB6C@10239|Viruses,4QUKM@29258|ssDNA viruses 10239|Viruses J Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_132341_2 1862825.A0A193CE78_9VIRU 1.14e-29 116.0 4QAZA@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_81758_1 1147.D082_13490 1.32e-17 80.5 COG3179@1|root,COG3179@2|Bacteria,1G1SC@1117|Cyanobacteria 1117|Cyanobacteria M PFAM Chitinase class I - - - - - - - - - - - - Glyco_hydro_19,PG_binding_1,Peptidase_M74,VanY k59_81758_3 314275.MADE_1014615 5.77e-10 56.6 29WMW@1|root,30I8Q@2|Bacteria,1NNZN@1224|Proteobacteria 1224|Proteobacteria S Protein of unknwon function (DUF3310) - - - - - - - - - - - - DUF3310 k59_190660_1 1475143.W8SNN0_9CIRC 1.13e-18 88.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_174071_1 652103.Rpdx1_2950 5.51e-64 213.0 COG4373@1|root,COG4373@2|Bacteria,1Q1RY@1224|Proteobacteria,2V9ED@28211|Alphaproteobacteria,3K5IV@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Mu-like prophage FluMu protein gp28 - - - - - - - - - - - - - k59_246930_2 1028800.RG540_CH13650 4.36e-32 117.0 2E0FP@1|root,300A6@2|Bacteria,1PQHQ@1224|Proteobacteria,2V2WQ@28211|Alphaproteobacteria,4BJS5@82115|Rhizobiaceae 28211|Alphaproteobacteria L Phage endonuclease I - - - - - - - - - - - - Phage_endo_I k59_181592_1 292564.Cyagr_0630 0.000769 42.4 COG1694@1|root,COG1694@2|Bacteria,1GA07@1117|Cyanobacteria,22SUI@167375|Cyanobium 1117|Cyanobacteria S MazG nucleotide pyrophosphohydrolase domain - - - - - - - - - - - - MazG k59_181592_4 948071.S4S2D9_9CAUD 2.8e-253 718.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QNQ6@10744|Podoviridae 10744|Podoviridae S ribonucleoside-triphosphate reductase activity - - - - - - - - - - - - - k59_181592_13 1197951.I6R0Z0_9CAUD 1.1e-60 201.0 4QGZN@10239|Viruses,4R0FF@35237|dsDNA viruses no RNA stage,4QTUK@28883|Caudovirales 28883|Caudovirales S nuclease activity - - - - - - - - - - - - - k59_181592_14 420324.KI911970_gene1439 5.18e-105 337.0 COG0749@1|root,COG0749@2|Bacteria,1P27P@1224|Proteobacteria,2TVEI@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DNA polymerase family A - - - - - - - - - - - - DNA_pol_A k59_181592_15 1283079.M1HMA6_9CAUD 5.76e-107 337.0 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales,4QNBW@10744|Podoviridae 10744|Podoviridae S DNA helicase activity - - - - - - - - - - - - - k59_15014_2 1122614.JHZF01000011_gene1718 5.32e-13 68.2 2C7JB@1|root,2ZXVG@2|Bacteria,1P7GB@1224|Proteobacteria,2UYPK@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_15014_3 1430331.EP10_10445 1.44e-24 98.2 COG3405@1|root,COG3405@2|Bacteria,1VBUA@1239|Firmicutes,4HMXV@91061|Bacilli 91061|Bacilli G Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - - - - - - - - - - - k59_124324_1 1207063.P24_15194 1.71e-08 63.2 28ST9@1|root,2ZF32@2|Bacteria,1PA9S@1224|Proteobacteria,2UYDQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_124324_10 1397284.AYMN01000002_gene2281 1.61e-09 57.0 2DN5T@1|root,32VQG@2|Bacteria,1N6A1@1224|Proteobacteria,1SB7Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_97682_3 1116472.MGMO_205c00030 1.92e-151 443.0 28IN7@1|root,2Z8NM@2|Bacteria,1NRFQ@1224|Proteobacteria,1SKG7@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Capsid protein (F protein) - - - - - - - - - - - - Phage_F k59_97682_6 1116472.MGMO_205c00050 4.21e-49 161.0 28HVF@1|root,2Z81Q@2|Bacteria,1NZPF@1224|Proteobacteria,1SRZ6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Bacteriophage scaffolding protein D - - - - - - - - - - - - gpD k59_106653_1 1234888.K0A2J2_9VIRU 1.44e-125 376.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_106653_6 105154.Q9MBU0_9VIRU 6.6e-27 114.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_197612_4 665942.HMPREF1022_00118 1.19e-22 98.6 2C9JF@1|root,32RPD@2|Bacteria,1N8CG@1224|Proteobacteria,42REW@68525|delta/epsilon subdivisions,2WNQ1@28221|Deltaproteobacteria,2MB30@213115|Desulfovibrionales 28221|Deltaproteobacteria S ERF superfamily - - - - - - - - - - - - ERF k59_231488_1 1692249.A0A0K1RLN8_9CIRC 1.71e-18 88.2 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_249025_1 225937.HP15_1957 3.28e-51 176.0 29UKS@1|root,30FY7@2|Bacteria,1RGKW@1224|Proteobacteria,1SKMS@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_149407_1 1165094.RINTHH_3920 4.75e-41 145.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_257350_2 105154.Q9MBU6_9VIRU 4e-28 113.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_124631_2 1498011.A0A096XUZ0_9CAUD 1.73e-53 171.0 4QB0C@10239|Viruses,4QPK3@28883|Caudovirales,4QNHV@10744|Podoviridae 10744|Podoviridae S Endodeoxyribonuclease RusA - - - - - - - - - - - - - k59_199210_6 1122973.KB904283_gene1040 2e-73 244.0 COG0507@1|root,COG0507@2|Bacteria 2|Bacteria L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD - - 3.1.11.5 ko:K01144 - - - - ko00000,ko01000 - - - AAA_30,PIF1,UvrD_C_2,Viral_helicase1 k59_91510_1 1218084.BBJK01000130_gene7124 5.64e-25 109.0 COG0457@1|root,COG0859@1|root,COG0457@2|Bacteria,COG0859@2|Bacteria,1MUZK@1224|Proteobacteria,2VJNV@28216|Betaproteobacteria,1K2NV@119060|Burkholderiaceae 28216|Betaproteobacteria M Tetratricopeptide TPR_2 repeat protein - - - - - - - - - - - - Glyco_transf_9,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8 k59_108141_2 445972.ANACOL_03344 1.52e-13 70.5 2CDFK@1|root,2Z8BH@2|Bacteria,1V43D@1239|Firmicutes,24KG0@186801|Clostridia,3WKBM@541000|Ruminococcaceae 186801|Clostridia H DNA N-6-adenine-methyltransferase (Dam) - - - - - - - - - - - - Dam k59_166095_1 1692256.A0A0K1RL85_9CIRC 3.52e-26 106.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_33519_1 1692256.A0A0K1RL85_9CIRC 2.23e-80 251.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_33519_2 1692242.A0A0K1RKZ2_9CIRC 3.55e-37 139.0 4QFEW@10239|Viruses,4QUKZ@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_16854_2 406818.XBJ1_2043 7.74e-25 104.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,1SMCU@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_207590_1 402626.Rpic_2546 3.91e-06 57.8 2EE5J@1|root,33803@2|Bacteria,1NB1A@1224|Proteobacteria,2VVPM@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_108146_1 2003327.CAPSD_BPCHP 9.67e-24 105.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_224122_1 488538.SAR116_0388 9.71e-58 197.0 COG0270@1|root,COG0270@2|Bacteria,1PPPJ@1224|Proteobacteria,2VAY7@28211|Alphaproteobacteria,4BSZM@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria H C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_124754_1 1238190.AMQY01000021_gene1593 2.98e-49 179.0 COG0749@1|root,COG0749@2|Bacteria,1MWX7@1224|Proteobacteria,1S0Q1@1236|Gammaproteobacteria 1236|Gammaproteobacteria L ORF located using Glimmer RBSfinder - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A,DNA_pol_A_exo1 k59_8630_1 1123057.P872_18440 2.55e-07 51.2 COG0494@1|root,COG0494@2|Bacteria,4PC4A@976|Bacteroidetes,47WT3@768503|Cytophagia 976|Bacteroidetes L nUDIX hydrolase - - - - - - - - - - - - - k59_133817_2 243233.MCA2908 6.68e-31 114.0 COG3628@1|root,COG3628@2|Bacteria,1NDEW@1224|Proteobacteria,1S5AU@1236|Gammaproteobacteria 1236|Gammaproteobacteria S baseplate protein - - - ko:K06903 - - - - ko00000 - - - GPW_gp25 k59_224973_1 2003327.CAPSD_BPCHP 6.82e-26 114.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_75760_2 1165094.RINTHH_3920 5.14e-61 201.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_75760_3 105154.Q9MBT9_9VIRU 1.28e-10 60.5 4QCC5@10239|Viruses,4QUKW@29258|ssDNA viruses,4QP4C@10841|Microviridae 10841|Microviridae S viral process - - - - - - - - - - - - - k59_42533_3 293826.Amet_2582 2.33e-12 72.0 COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,1TPHP@1239|Firmicutes,249MR@186801|Clostridia,36FKT@31979|Clostridiaceae 186801|Clostridia KL Belongs to the N(4) N(6)-methyltransferase family - - - - - - - - - - - - N6_N4_Mtase,ParBc k59_125542_1 1117943.SFHH103_00150 1.91e-14 84.0 2DPZ1@1|root,3340X@2|Bacteria,1R2EE@1224|Proteobacteria,2TZIB@28211|Alphaproteobacteria,4BP2Q@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_233141_1 742733.HMPREF9469_05023 4.41e-37 132.0 2CGG9@1|root,2ZVSJ@2|Bacteria,1V633@1239|Firmicutes,24HD0@186801|Clostridia,222RY@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_108826_2 69279.BG36_20840 1.72e-29 115.0 2DWRQ@1|root,341KN@2|Bacteria,1NYD8@1224|Proteobacteria,2UTQ9@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_249784_3 1379719.S5TMX6_9CIRC 1.38e-28 118.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_150377_1 1452718.JBOY01000021_gene719 4.86e-74 261.0 COG3378@1|root,COG3378@2|Bacteria,1QVIS@1224|Proteobacteria,1S02S@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Psort location Cytoplasmic, score - - - ko:K06919 - - - - ko00000 - - - Prim-Pol,Toprim_3,Toprim_4 k59_92383_2 1379709.S5TMV0_9CIRC 4.62e-43 156.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_183513_1 1788454.A0A190WHE4_9CIRC 9.46e-47 162.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_259376_2 1004785.AMBLS11_12345 2.25e-05 53.9 28H88@1|root,2Z7K7@2|Bacteria,1R5AY@1224|Proteobacteria,1RSD9@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_259376_4 1121441.AUCX01000008_gene2276 1.1e-05 55.1 COG4388@1|root,COG4388@2|Bacteria,1R5B8@1224|Proteobacteria,43B2G@68525|delta/epsilon subdivisions,2X6GH@28221|Deltaproteobacteria,2MC8J@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_59871_2 420324.KI911970_gene1445 2.25e-45 159.0 COG0258@1|root,COG0258@2|Bacteria,1MYSI@1224|Proteobacteria,2U60N@28211|Alphaproteobacteria 28211|Alphaproteobacteria L 5'-3' exonuclease, N-terminal resolvase-like domain - - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc_N k59_192387_1 557598.LHK_01542 6.2e-137 397.0 28HXV@1|root,2Z83C@2|Bacteria,1PJBP@1224|Proteobacteria,2VZV5@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_2450_2 105154.Q9MBU3_9VIRU 0.000332 48.1 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_168134_1 755178.Cyan10605_2091 5.79e-116 342.0 COG0675@1|root,COG0675@2|Bacteria,1G0U9@1117|Cyanobacteria 1117|Cyanobacteria L COG0675 Transposase and inactivated derivatives - - - ko:K07496 - - - - ko00000 - - - HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon k59_151696_1 1692252.A0A0K1RL35_9CIRC 3.78e-23 96.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_135083_1 563192.HMPREF0179_00147 4.02e-11 65.5 28JXH@1|root,2ZA3Z@2|Bacteria,1R8CZ@1224|Proteobacteria,42WKC@68525|delta/epsilon subdivisions,2WUAM@28221|Deltaproteobacteria,2MEKQ@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_201124_2 1073999.BN137_1188 6.73e-19 80.9 2D7I9@1|root,32TP3@2|Bacteria,1N2ZM@1224|Proteobacteria,1S9DB@1236|Gammaproteobacteria 1236|Gammaproteobacteria S phage protein ybcO - - - - - - - - - - - DUF1364 k59_250583_1 1234888.K0A2J2_9VIRU 9.83e-82 261.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_250583_6 1234888.K0A2J2_9VIRU 2.8e-78 249.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_192485_1 756276.A0A096VKL9_9VIRU 1.95e-26 107.0 4QBMX@10239|Viruses,4QV9I@35237|dsDNA viruses no RNA stage 10239|Viruses S Pfam:Tube - GO:0005575,GO:0019012 - - - - - - - - - - - k59_68407_1 999611.KI421504_gene3031 9.48e-30 110.0 2E04N@1|root,32VT5@2|Bacteria,1N310@1224|Proteobacteria,2URAT@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_68407_2 1477404.A0A023NGK2_9CAUD 1.68e-43 149.0 4QAQV@10239|Viruses,4QUPK@35237|dsDNA viruses no RNA stage,4QPCB@28883|Caudovirales,4QNFC@10744|Podoviridae 10744|Podoviridae S hydrolase activity - - - - - - - - - - - - - k59_226200_1 105154.Q9MBU6_9VIRU 1.37e-91 293.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_10175_1 536232.CLM_2512 1.11e-27 117.0 COG5283@1|root,COG5293@1|root,COG5283@2|Bacteria,COG5293@2|Bacteria,1UHQM@1239|Firmicutes,25E9Q@186801|Clostridia,36USH@31979|Clostridiaceae 186801|Clostridia D phage tail tape measure protein - - - - - - - - - - - - PhageMin_Tail k59_84649_1 1562701.BBOF01000016_gene480 3.2e-25 108.0 COG5377@1|root,COG5377@2|Bacteria,1MWP8@1224|Proteobacteria,2VJH5@28216|Betaproteobacteria,1K2RX@119060|Burkholderiaceae 28216|Betaproteobacteria L YqaJ-like viral recombinase domain - - - - - - - - - - - - YqaJ k59_209141_2 1589733.A0A0C5AMW6_9CAUD 1.24e-41 150.0 4QCS3@10239|Viruses,4QU2E@28883|Caudovirales,4QKJF@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_209141_4 268747.Q58LK9_BPPRS 9.92e-35 132.0 4QDJF@10239|Viruses,4QVQ0@35237|dsDNA viruses no RNA stage,4QR89@28883|Caudovirales,4QICF@10662|Myoviridae 10662|Myoviridae S Virus neck protein - GO:0005575,GO:0019012 - - - - - - - - - - - k59_78310_2 326426.Bbr_1453 2.47e-06 51.6 COG3613@1|root,COG3613@2|Bacteria,2IHGG@201174|Actinobacteria,4D0T2@85004|Bifidobacteriales 201174|Actinobacteria F Nucleoside 2-deoxyribosyltransferase - - - - - - - - - - - - Nuc_deoxyrib_tr k59_28913_1 694060.D2K079_9CAUD 3.9e-23 103.0 4QCWQ@10239|Viruses,4QYP8@35237|dsDNA viruses no RNA stage,4QQZU@28883|Caudovirales,4QK15@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_36455_1 1574422.A0A0A1ENW9_9CIRC 1.01e-35 135.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_243751_1 1468179.A0A0C4K5Z2_9VIRU 2.92e-20 97.8 4QAKM@10239|Viruses 10239|Viruses S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_243751_2 1197951.I6R0Y7_9CAUD 1.45e-28 115.0 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales 28883|Caudovirales S DnaB-like helicase C terminal domain - - - - - - - - - - - - - k59_193800_3 1140.Synpcc7942_1292 0.000112 52.4 COG0358@1|root,COG0358@2|Bacteria,1G0TV@1117|Cyanobacteria,1GZ6N@1129|Synechococcus 1117|Cyanobacteria L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,Toprim_2,Toprim_N,zf-CHC2 k59_193800_6 1033743.CAES01000032_gene973 1.07e-131 431.0 COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,4H9T3@91061|Bacilli,26QTS@186822|Paenibacillaceae 91061|Bacilli L DNA polymerase dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k59_85734_1 205914.HS_1385 1.04e-116 355.0 COG1783@1|root,COG1783@2|Bacteria,1RAGC@1224|Proteobacteria 1224|Proteobacteria S phage Terminase large subunit - - - - - - - - - - - - - k59_85734_2 1192759.AKIB01000023_gene2885 1.99e-20 93.2 28P6A@1|root,2ZC10@2|Bacteria,1RBZE@1224|Proteobacteria,2UQEG@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_128595_1 1150626.PHAMO_280158 3.32e-12 65.9 COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,2U7B5@28211|Alphaproteobacteria,2JS8T@204441|Rhodospirillales 204441|Rhodospirillales F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA dut - - - - - - - - - - - dUTPase k59_235247_11 666681.M301_0132 5.54e-49 179.0 2D784@1|root,32TNH@2|Bacteria,1N098@1224|Proteobacteria,2VX0M@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_53899_1 889378.Spiaf_2417 1.02e-126 387.0 COG0209@1|root,COG0209@2|Bacteria 2|Bacteria F ribonucleoside-diphosphate reductase activity rtpR - 1.1.98.6,1.17.4.1 ko:K00525,ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024,R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,LAGLIDADG_3,Ribonuc_red_lgC k59_210460_3 1609634.A0A0C5AFV4_9VIRU 4.77e-178 520.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_193995_4 1385658.U5KPZ6_9VIRU 1.81e-10 62.4 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_94577_2 225937.HP15_1949 8.1e-13 75.9 2DZHM@1|root,32VAY@2|Bacteria,1N0DC@1224|Proteobacteria,1SP9I@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_222132_1 2850.Phatr47174 3.3e-09 63.2 2CYAC@1|root,2S35N@2759|Eukaryota,2XGMQ@2836|Bacillariophyta 2836|Bacillariophyta S Methyltransferase domain - - - - - - - - - - - - Methyltransf_24 k59_229277_1 1500257.JQNM01000001_gene4163 0.000541 45.1 COG1215@1|root,COG1215@2|Bacteria,1NDPE@1224|Proteobacteria,2TSCT@28211|Alphaproteobacteria,4B7N8@82115|Rhizobiaceae 28211|Alphaproteobacteria M Succinoglycan biosynthesis protein exoA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K16557 - - - - ko00000,ko01000,ko01003 - GT2 - Glycos_transf_2 k59_229277_2 226186.BT_0465 1.09e-24 107.0 COG1091@1|root,COG1091@2|Bacteria,4NE3K@976|Bacteroidetes,2FN7H@200643|Bacteroidia,4AMIY@815|Bacteroidaceae 976|Bacteroidetes M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose rfbD - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind k59_30835_2 1391025.T1YRV6_9VIRU 2.84e-08 57.4 4QHM9@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_262662_1 556269.ACDQ01000002_gene1166 7.84e-28 107.0 2CC49@1|root,2ZBQQ@2|Bacteria,1RA92@1224|Proteobacteria,2VYII@28216|Betaproteobacteria 28216|Betaproteobacteria S Protein of unknown function (DUF1367) - - - - - - - - - - - - DUF1367 k59_138486_1 1122614.JHZF01000011_gene1718 5.66e-17 78.2 2C7JB@1|root,2ZXVG@2|Bacteria,1P7GB@1224|Proteobacteria,2UYPK@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_87259_1 1121957.ATVL01000006_gene2677 1.88e-27 115.0 COG5280@1|root,COG5283@1|root,COG5280@2|Bacteria,COG5283@2|Bacteria,4NKDN@976|Bacteroidetes 976|Bacteroidetes D Phage tail tape measure protein, TP901 family - - - - - - - - - - - - PhageMin_Tail k59_204716_1 1316932.MHH_c17950 8.19e-27 111.0 COG3566@1|root,COG3566@2|Bacteria,1QWCX@1224|Proteobacteria,1RZS8@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - DUF2213 k59_155161_1 1121459.AQXE01000001_gene2769 4.96e-15 77.4 2AFZH@1|root,3163D@2|Bacteria,1RJUP@1224|Proteobacteria,42ZBP@68525|delta/epsilon subdivisions,2WTYW@28221|Deltaproteobacteria,2MDNE@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_204722_2 1300143.CCAV010000006_gene4340 2.52e-33 123.0 COG0863@1|root,COG0863@2|Bacteria,4NQQ1@976|Bacteroidetes,1I957@117743|Flavobacteriia,3ZRIJ@59732|Chryseobacterium 976|Bacteroidetes L DNA methylase - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_262666_1 1524882.A0A076G6X1_9CAUD 8.76e-72 222.0 4QCB0@10239|Viruses,4QPFH@28883|Caudovirales,4QKQY@10699|Siphoviridae 10699|Siphoviridae S YqaJ-like viral recombinase domain - - - - - - - - - - - - - k59_122086_1 1618248.A0A0C5IB82_9CIRC 5.11e-38 136.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_95925_2 1556290.A0A0A0RL61_9CAUD 1.72e-86 271.0 4QAK6@10239|Viruses,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - GO:0005575,GO:0019012,GO:0019028,GO:0032991,GO:0044423,GO:0046806 - - - - - - - - - - - k59_188107_1 349521.HCH_05649 2.53e-15 80.1 COG4733@1|root,COG4733@2|Bacteria,1MXB4@1224|Proteobacteria,1RRUV@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Putative phage tail protein - - - - - - - - - - - - Phage-tail_3 k59_47500_1 1209072.ALBT01000003_gene703 5.06e-44 157.0 COG0582@1|root,COG0582@2|Bacteria,1QWI5@1224|Proteobacteria,1T2VS@1236|Gammaproteobacteria 1236|Gammaproteobacteria L viral genome integration into host DNA - - - - - - - - - - - - - k59_147435_1 1165094.RINTHH_3920 1.72e-62 207.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_147435_3 105154.Q9MBU6_9VIRU 3.22e-152 455.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_147435_4 105154.Q9MBU3_9VIRU 1.38e-15 80.1 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_116553_3 873533.HMPREF0663_10799 5.09e-43 149.0 COG1262@1|root,COG1262@2|Bacteria,4NEUZ@976|Bacteroidetes 976|Bacteroidetes KLT PFAM Formylglycine-generating sulfatase enzyme - - - - - - - - - - - - BNR_2,FGE-sulfatase k59_116553_5 1429767.W6AQU3_9CAUD 7.03e-06 49.3 4QAR6@10239|Viruses,4QUTK@35237|dsDNA viruses no RNA stage,4QPS2@28883|Caudovirales,4QNRU@10744|Podoviridae 10744|Podoviridae S dUTPase - - - - - - - - - - - - - k59_99936_4 1234888.K0A2J2_9VIRU 2.72e-132 399.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_99936_6 1234888.K0A2R8_9VIRU 3.33e-35 132.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_182884_2 105154.Q9MBU2_9VIRU 1.6e-13 71.2 4QDBB@10239|Viruses,4QUM0@29258|ssDNA viruses,4QP4D@10841|Microviridae 10841|Microviridae S Chlamydia-phage Chp2 scaffold (Chlamy_scaf) - - - - - - - - - - - - - k59_182884_4 1609634.A0A0C5AFT2_9VIRU 4.6e-69 224.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_182884_6 105154.Q9MBU6_9VIRU 5.51e-204 585.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_75123_2 1437608.BBIA_1039 1.01e-07 60.1 28MKK@1|root,2ZAWR@2|Bacteria,2IS2W@201174|Actinobacteria,4D1DD@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - RNA_helicase,Viral_Rep k59_257565_1 1347393.HG726022_gene3605 7.87e-47 166.0 COG3723@1|root,COG3723@2|Bacteria,4P3K6@976|Bacteroidetes,2G2ZR@200643|Bacteroidia,4AW7B@815|Bacteroidaceae 976|Bacteroidetes L RecT family - - - - - - - - - - - - RecT k59_75124_1 1279017.AQYJ01000026_gene12 1.64e-37 135.0 COG1396@1|root,COG1396@2|Bacteria 2|Bacteria K sequence-specific DNA binding cI - - - - - - - - - - - HTH_3,HTH_31,Peptidase_S24 k59_149826_4 1000565.METUNv1_03731 4.43e-50 178.0 COG0464@1|root,COG0464@2|Bacteria,1QU82@1224|Proteobacteria,2WHSD@28216|Betaproteobacteria,2KW8F@206389|Rhodocyclales 206389|Rhodocyclales O Zonular occludens toxin (Zot) - - - - - - - - - - - - Zot k59_608_1 369723.Strop_1948 1.63e-91 293.0 COG4676@1|root,COG4676@2|Bacteria,2GPA6@201174|Actinobacteria,4DCBY@85008|Micromonosporales 201174|Actinobacteria S Protein conserved in bacteria - - - - - - - - - - - - - k59_116665_1 1262513.K7Z9P2_9CAUD 2.08e-24 110.0 4QAKZ@10239|Viruses,4QUSW@35237|dsDNA viruses no RNA stage,4QPYH@28883|Caudovirales,4QIYN@10662|Myoviridae 10662|Myoviridae S exonuclease activity - - - - - - - - - - - - - k59_191202_1 288000.BBta_6754 2.51e-21 102.0 2F84W@1|root,340I7@2|Bacteria,1R3XR@1224|Proteobacteria,2U20U@28211|Alphaproteobacteria,3JVBF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_257700_1 521000.PROVRETT_06008 2.06e-59 209.0 28JKJ@1|root,2Z9DD@2|Bacteria,1MUN2@1224|Proteobacteria,1RQIP@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage P22-like portal protein - - - - - - - - - - - - P22_portal k59_249318_1 1477404.A0A023NH97_9CAUD 1.52e-97 310.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QNBK@10744|Podoviridae 10744|Podoviridae S Ribonucleotide reductase, barrel domain - - - - - - - - - - - - - k59_167646_3 1986029.Q9MBM8_9VIRU 4.02e-154 460.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_158924_2 1379695.S5TNA9_9CIRC 9.29e-39 145.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_84404_2 1234888.K0A2J2_9VIRU 6.88e-53 185.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_51506_1 1618248.A0A0C5IB82_9CIRC 3.8e-31 122.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_101138_1 1732201.A0A0N9N7I3_9CIRC 2.23e-20 93.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_26819_1 1125725.HMPREF1325_1303 1.21e-41 147.0 COG3723@1|root,COG3723@2|Bacteria,2JADR@203691|Spirochaetes 203691|Spirochaetes L PFAM DNA single-strand annealing protein RecT-like - - - - - - - - - - - - RecT k59_233524_2 444859.E3SIB0_9CAUD 4.78e-05 53.5 4QCZH@10239|Viruses,4QPND@28883|Caudovirales,4QI11@10662|Myoviridae 10662|Myoviridae S Bacteriophage T4 gp9/10-like protein - GO:0005575,GO:0019012,GO:0044423,GO:0098015,GO:0098025 - - - - - - - - - - - k59_51507_1 1158294.JOMI01000007_gene779 7.55e-59 200.0 COG1783@1|root,COG1783@2|Bacteria,4NHPB@976|Bacteroidetes,2FR95@200643|Bacteroidia 976|Bacteroidetes S Phage terminase, large subunit, PBSX family - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C k59_59583_1 367299.JOEE01000010_gene3311 2.2e-15 83.2 COG0209@1|root,COG0209@2|Bacteria,2GKX9@201174|Actinobacteria,4FF7G@85021|Intrasporangiaceae 201174|Actinobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdA - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN k59_242032_1 1265502.KB905934_gene3148 2.44e-28 117.0 COG0616@1|root,COG0616@2|Bacteria,1QGPW@1224|Proteobacteria,2VJ0N@28216|Betaproteobacteria,4AB1E@80864|Comamonadaceae 28216|Betaproteobacteria OU PFAM peptidase S49 - - - - - - - - - - - - Peptidase_S49 k59_84414_1 1123503.KB908056_gene1234 5.5e-24 96.3 2ARIQ@1|root,31GV5@2|Bacteria,1RM5P@1224|Proteobacteria,2U9D1@28211|Alphaproteobacteria,2KJK5@204458|Caulobacterales 204458|Caulobacterales S Antirestriction protein (ArdA) - - - - - - - - - - - - ArdA k59_250305_5 1219035.NT2_13_00580 6.57e-58 200.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_126306_1 1197951.I6S6K3_9CAUD 3.99e-10 69.7 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales 28883|Caudovirales S N-acetylmuramoyl-L-alanine amidase activity - - - - - - - - - - - - - k59_151134_1 393305.YE2324 4.66e-56 190.0 28KYW@1|root,2ZAE8@2|Bacteria,1MX3D@1224|Proteobacteria,1RQQR@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4055) - - - - - - - - - - - - DUF4055 k59_134539_4 1155714.KB891988_gene1269 8.78e-14 80.5 COG0791@1|root,COG3409@1|root,COG0791@2|Bacteria,COG3409@2|Bacteria,2I61A@201174|Actinobacteria 201174|Actinobacteria M Peptidoglycan-binding domain 1 protein - - - - - - - - - - - - NLPC_P60,PG_binding_1 k59_209541_2 1385658.U5KPZ6_9VIRU 8.68e-51 178.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_44330_1 691965.D4P7D3_9CAUD 4.4e-34 131.0 4QAYV@10239|Viruses,4QUZ7@35237|dsDNA viruses no RNA stage,4QPU3@28883|Caudovirales,4QKKX@10699|Siphoviridae 10699|Siphoviridae S Phage portal protein - - - - - - - - - - - - - k59_201782_3 1208918.CDEE_0591 1.37e-06 56.2 COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,2VHDG@28216|Betaproteobacteria,1KPN9@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria I Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxA - 2.3.1.129 ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 M00060 R04567 RC00039,RC00055 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Acetyltransf_11,Hexapep k59_135635_1 1788454.A0A190WHE4_9CIRC 9.39e-43 150.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_152407_1 1160718.SU9_10379 2.12e-104 328.0 COG0749@1|root,COG0749@2|Bacteria,2I975@201174|Actinobacteria 201174|Actinobacteria L COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains - - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - DNA_pol_A,DNA_pol_A_exo1 k59_226764_2 948071.S4S2E3_9CAUD 6.91e-25 99.4 4QGDB@10239|Viruses,4QZHU@35237|dsDNA viruses no RNA stage,4QSG0@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_260241_1 105154.Q9MBU6_9VIRU 4.38e-50 176.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_160211_1 1520935.A0A0H3UB63_9CIRC 1.28e-18 90.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_144406_1 1986029.Q9MBM8_9VIRU 1.92e-77 253.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_226920_1 1122201.AUAZ01000017_gene2947 2.42e-117 368.0 COG0749@1|root,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,465DD@72275|Alteromonadaceae 1236|Gammaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity - - - - - - - - - - - - DNA_pol_A k59_10822_1 1348663.KCH_15020 5.81e-21 90.5 2EGA5@1|root,33A1Y@2|Bacteria,2GSDD@201174|Actinobacteria 201174|Actinobacteria S HNH endonuclease - - - - - - - - - - - - HNH_3 k59_28244_2 105154.Q9MBU6_9VIRU 1.61e-148 441.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_146463_2 999423.HMPREF9161_01357 1.62e-53 179.0 COG1089@1|root,COG1089@2|Bacteria,1TQ9T@1239|Firmicutes,4H2Q3@909932|Negativicutes 909932|Negativicutes M Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose gmd - 4.2.1.47 ko:K01711 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R00888 RC00402 ko00000,ko00001,ko01000 - - - GDP_Man_Dehyd k59_121175_1 179237.Q8W6H9_9CAUD 1.92e-18 88.2 4QFIA@10239|Viruses,4QZJU@35237|dsDNA viruses no RNA stage,4QU30@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_221467_2 103372.F4WEQ8 1.04e-06 52.8 2CXGH@1|root,2RX9T@2759|Eukaryota,39YTV@33154|Opisthokonta,3BMVG@33208|Metazoa,3DDBX@33213|Bilateria,42250@6656|Arthropoda,3SITN@50557|Insecta,46M7W@7399|Hymenoptera 33208|Metazoa - - - - - - - - - - - - - - Parvo_coat_N k59_37386_2 438753.AZC_3607 1.2e-127 407.0 COG5108@1|root,COG5108@2|Bacteria,1PIWB@1224|Proteobacteria,2U1JR@28211|Alphaproteobacteria 28211|Alphaproteobacteria K DNA-dependent RNA polymerase - - - - - - - - - - - - RNA_pol,RPOL_N k59_12560_1 1283078.M1IPK2_9CAUD 3.36e-92 293.0 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales,4QNBW@10744|Podoviridae 10744|Podoviridae S DNA helicase activity - - - - - - - - - - - - - k59_171027_1 1175654.A0A0S0NAG2_9CAUD 6.53e-41 154.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_161887_1 1123035.ARLA01000022_gene676 1.3e-16 81.3 COG0500@1|root,COG2226@2|Bacteria,4P4Z8@976|Bacteroidetes 976|Bacteroidetes Q Sulfotransferase family - - - - - - - - - - - - Sulfotransfer_2 k59_161887_2 404589.Anae109_1425 2.93e-08 63.9 COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42R6N@68525|delta/epsilon subdivisions,2WP3W@28221|Deltaproteobacteria,2Z144@29|Myxococcales 28221|Deltaproteobacteria M Glycosyltransferase Family 4 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k59_79316_1 1385658.U5KPZ6_9VIRU 8.47e-118 358.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_46776_2 1234888.K0A2R8_9VIRU 6.11e-20 93.6 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_180672_1 1379719.S5TMX6_9CIRC 1.26e-21 97.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_63524_2 663610.JQKO01000006_gene2685 5.66e-27 120.0 2EBXN@1|root,335X0@2|Bacteria,1RCC3@1224|Proteobacteria,2U2ZA@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_173093_1 291112.PAU_03126 6.99e-31 115.0 2CC49@1|root,2ZBQQ@2|Bacteria,1RA92@1224|Proteobacteria,1S3BM@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF1367) - - - - - - - - - - - - DUF1367 k59_156330_1 1385658.U5KPZ6_9VIRU 3.41e-79 251.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_230463_1 172088.AUGA01000033_gene4625 6.19e-52 175.0 COG3170@1|root,COG3170@2|Bacteria,1R69E@1224|Proteobacteria,2U3B9@28211|Alphaproteobacteria 28211|Alphaproteobacteria NU Phage P22-like portal protein - - - - - - - - - - - - - k59_39078_1 1385658.U5KPZ6_9VIRU 7.91e-73 235.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_123300_2 756275.H2BCT9_9CAUD 0.000181 52.8 4QEXP@10239|Viruses,4QUDQ@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_173099_1 1692242.A0A0K1RKZ2_9CIRC 2.92e-27 111.0 4QFEW@10239|Viruses,4QUKZ@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_80793_1 2003327.REP_BPCHP 4.69e-08 58.2 4QCVK@10239|Viruses,4QUMV@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_14202_1 232348.ADXL01000014_gene732 1.77e-35 131.0 COG5055@1|root,COG5055@2|Bacteria,1GPCA@1117|Cyanobacteria,1H2VP@1129|Synechococcus 1117|Cyanobacteria L COG5055 Recombination DNA repair protein (RAD52 pathway) - - - - - - - - - - - - Rad52_Rad22 k59_123303_1 756277.M1PJJ8_9VIRU 1.31e-14 78.6 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage 10239|Viruses S DnaB-like helicase C terminal domain - - - - - - - - - - - - - k59_263900_2 331869.BAL199_00085 3.43e-28 109.0 COG0494@1|root,COG0494@2|Bacteria,1QZ2V@1224|Proteobacteria,2TY3A@28211|Alphaproteobacteria,4BT04@82117|unclassified Alphaproteobacteria 2|Bacteria L NUDIX domain mutT - 2.7.7.53,3.6.1.13,3.6.1.17,3.6.1.55,3.6.1.61,3.6.1.67 ko:K01515,ko:K01518,ko:K03574,ko:K08310,ko:K18445,ko:K19710 ko00230,ko00240,ko00790,map00230,map00240,map00790 M00126 R00126,R00184,R00969,R01054,R01232,R01618,R02805,R04638 RC00002,RC02753,RC02795 ko00000,ko00001,ko00002,ko01000,ko03400 - - - His_Phos_1,NUDIX k59_7851_2 1417599.U6C6Z0_9CAUD 4.5e-22 95.5 4QB55@10239|Viruses,4QW4S@35237|dsDNA viruses no RNA stage,4QSJ0@28883|Caudovirales,4QNGX@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_139955_1 1502851.FG93_03501 4.06e-28 110.0 2AGTB@1|root,3171D@2|Bacteria,1RJGM@1224|Proteobacteria,2UJ68@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_88066_2 1008459.TASI_0454 5.29e-07 56.2 2DT4R@1|root,33IPZ@2|Bacteria,1NIT6@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_230575_1 1385658.U5KPZ6_9VIRU 2.82e-93 296.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_131581_5 1122927.KB895423_gene3757 6.4e-58 225.0 COG3420@1|root,COG4099@1|root,COG5492@1|root,COG3420@2|Bacteria,COG4099@2|Bacteria,COG5492@2|Bacteria,1VR20@1239|Firmicutes,4HVGA@91061|Bacilli,26V79@186822|Paenibacillaceae 91061|Bacilli P Right handed beta helix region - - - - - - - - - - - - Beta_helix,Big_2 k59_115309_3 1380394.JADL01000001_gene2060 2.12e-21 91.3 28N1N@1|root,2ZB7Q@2|Bacteria,1R86T@1224|Proteobacteria,2U0A6@28211|Alphaproteobacteria,2JRMI@204441|Rhodospirillales 204441|Rhodospirillales H Sulfotransferase domain - - - - - - - - - - - - Sulfotransfer_1 k59_214691_1 1618248.A0A0C5IB82_9CIRC 8.46e-85 263.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_182362_1 114615.BRADO3649 1.01e-15 81.6 2A632@1|root,30UVF@2|Bacteria,1PE7G@1224|Proteobacteria,2UUNF@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_165565_4 1618249.A0A0C5IBT4_9CIRC 9.89e-26 110.0 4QB6C@10239|Viruses,4QUKM@29258|ssDNA viruses 10239|Viruses J Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_82652_1 1229781.C272_06079 5.41e-15 83.2 COG1475@1|root,COG1475@2|Bacteria,2GNRN@201174|Actinobacteria,4F8AF@85019|Brevibacteriaceae 201174|Actinobacteria K ParB-like nuclease domain parB GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005694,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0060187,GO:0071944 - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_182372_1 1123255.JHYS01000027_gene1746 8.51e-13 75.5 COG1040@1|root,COG1040@2|Bacteria,1QV41@1224|Proteobacteria,2VMZ1@28216|Betaproteobacteria,4AB0B@80864|Comamonadaceae 28216|Betaproteobacteria FL competence protein - - - - - - - - - - - - - k59_16001_1 1122201.AUAZ01000010_gene2520 6.73e-79 248.0 29UKS@1|root,30FY7@2|Bacteria,1RGKW@1224|Proteobacteria,1SKMS@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_40863_1 1340829.S5Y5D9_9CAUD 1.59e-108 356.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QKNE@10699|Siphoviridae 10699|Siphoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_107129_2 1385658.U5KNR1_9VIRU 8.73e-72 231.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_107129_4 1385658.U5KPZ6_9VIRU 1.22e-184 536.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_107129_6 105154.Q9MBU2_9VIRU 1.55e-16 78.6 4QDBB@10239|Viruses,4QUM0@29258|ssDNA viruses,4QP4D@10841|Microviridae 10841|Microviridae S Chlamydia-phage Chp2 scaffold (Chlamy_scaf) - - - - - - - - - - - - - k59_247739_1 105154.Q9MBU6_9VIRU 5e-45 160.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_256370_3 342113.DM82_4346 1.35e-47 182.0 COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria 2|Bacteria L DNA primase activity - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - AAA_25,DnaB_C,Toprim_2,Toprim_4 k59_82661_1 1732201.A0A0N9N7I3_9CIRC 7.83e-34 132.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_98489_1 707757.D5JFT2_9CAUD 4.33e-19 92.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QI82@10662|Myoviridae 10662|Myoviridae S virus tail, fiber - - - - - - - - - - - - - k59_165576_1 1121935.AQXX01000096_gene2527 3.7e-25 117.0 COG5283@1|root,COG5283@2|Bacteria,1QZAD@1224|Proteobacteria,1RYP3@1236|Gammaproteobacteria,1XMG9@135619|Oceanospirillales 135619|Oceanospirillales D nuclear chromosome segregation - - - - - - - - - - - - - k59_107333_1 190486.XAC1064 3.82e-75 245.0 COG5410@1|root,COG5410@2|Bacteria,1N0W2@1224|Proteobacteria,1TCS2@1236|Gammaproteobacteria,1X9QW@135614|Xanthomonadales 135614|Xanthomonadales K chromosome segregation - - - - - - - - - - - - - k59_198677_1 1219035.NT2_13_00580 3.94e-52 185.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_17044_1 670307.HYPDE_32038 0.000364 46.6 COG3926@1|root,COG3926@2|Bacteria,1QV3R@1224|Proteobacteria,2UDA8@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Glycosyl hydrolase 108 - - - - - - - - - - - - Glyco_hydro_108,PG_binding_3 k59_249322_1 1437882.AZRU01000034_gene459 2.68e-39 147.0 28JXH@1|root,2ZA3Z@2|Bacteria,1R8CZ@1224|Proteobacteria,1TC26@1236|Gammaproteobacteria,1YJPC@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_249322_10 400668.Mmwyl1_0577 3.07e-42 145.0 2AFF0@1|root,315F0@2|Bacteria,1RHGE@1224|Proteobacteria,1S6YG@1236|Gammaproteobacteria,1XKMC@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k59_158146_2 1692249.A0A0K1RL40_9CIRC 1.23e-50 176.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_191237_1 1260356.D920_00109 0.000669 49.7 COG0438@1|root,COG0438@2|Bacteria,1V2PF@1239|Firmicutes,4HH5A@91061|Bacilli,4B644@81852|Enterococcaceae 91061|Bacilli M Glycosyl transferases group 1 ytcC - - ko:K06338 - - - - ko00000 - - - Glyco_transf_4,Glycos_transf_1 k59_17109_1 1385658.U5KNR1_9VIRU 1.03e-40 149.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_17109_3 105154.Q9MBU6_9VIRU 2.63e-158 470.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_108435_1 935261.JAGL01000009_gene1171 1.62e-40 146.0 COG0258@1|root,COG0258@2|Bacteria,1MYSI@1224|Proteobacteria,2U60N@28211|Alphaproteobacteria 28211|Alphaproteobacteria L 5'-3' exonuclease, N-terminal resolvase-like domain - - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc_N k59_8995_1 226186.BT_2311 3.36e-16 83.2 COG3969@1|root,COG3969@2|Bacteria,4NJR7@976|Bacteroidetes,2FRAF@200643|Bacteroidia,4ANGB@815|Bacteroidaceae 976|Bacteroidetes S Domain of unknown function (DUF3440) - - - - - - - - - - - - DUF3440,PAPS_reduct k59_58660_1 1379717.S5SY19_9CIRC 1.22e-42 155.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_133428_1 68170.KL590474_gene5959 2.17e-66 213.0 COG2887@1|root,COG2887@2|Bacteria,2IBTP@201174|Actinobacteria,4E5WP@85010|Pseudonocardiales 201174|Actinobacteria L Belongs to the helicase family. UvrD subfamily - - - - - - - - - - - - PDDEXK_1 k59_183138_2 157783.LK03_13300 1.81e-22 90.5 2D7I9@1|root,32TP3@2|Bacteria,1N2ZM@1224|Proteobacteria,1S9DB@1236|Gammaproteobacteria 1236|Gammaproteobacteria S phage protein ybcO - - - - - - - - - - - DUF1364 k59_183138_3 371042.NG99_23585 5.32e-73 230.0 28J67@1|root,2Z91Y@2|Bacteria,1R7RG@1224|Proteobacteria,1RZB8@1236|Gammaproteobacteria,3X71A@551|Erwinia 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_224592_2 1140001.I571_01849 1.97e-20 85.5 2EK5K@1|root,33DW0@2|Bacteria,1VKGK@1239|Firmicutes,4HRYF@91061|Bacilli,4B4AI@81852|Enterococcaceae 91061|Bacilli S Putative phage holin Dp-1 - - - - - - - - - - - - Phage_holin_Dp1 k59_92733_5 1122612.AUBA01000021_gene2603 3.36e-08 53.5 COG0776@1|root,COG0776@2|Bacteria 2|Bacteria L regulation of translation hupB - - ko:K03530,ko:K04764 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding k59_92733_8 1149133.ppKF707_0757 1.62e-05 52.8 COG0237@1|root,COG0237@2|Bacteria,1P8TB@1224|Proteobacteria,1TC1Y@1236|Gammaproteobacteria,1YJNV@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria H dephospho-CoA kinase activity - - - - - - - - - - - - - k59_92733_13 102129.Lepto7375DRAFT_7196 8.13e-28 124.0 COG0210@1|root,COG0210@2|Bacteria,1GQP4@1117|Cyanobacteria,1HDFZ@1150|Oscillatoriales 1117|Cyanobacteria L PFAM UvrD REP helicase - - - - - - - - - - - - UvrD-helicase,UvrD_C k59_92733_16 756282.M4SPQ9_9CAUD 1.5e-59 203.0 4QAUS@10239|Viruses,4QURX@35237|dsDNA viruses no RNA stage,4QQ2S@28883|Caudovirales,4QKRA@10699|Siphoviridae 10699|Siphoviridae S flavin adenine dinucleotide binding - - - - - - - - - - - - - k59_92733_19 1472912.A0A023NGC4_9CAUD 7.07e-08 56.6 4QAQV@10239|Viruses,4QUPK@35237|dsDNA viruses no RNA stage,4QPCB@28883|Caudovirales 28883|Caudovirales S protein disulfide oxidoreductase activity - - - - - - - - - - - - - k59_175365_1 941449.dsx2_1539 9.6e-50 181.0 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,42Z58@68525|delta/epsilon subdivisions,2WTW4@28221|Deltaproteobacteria,2M8HG@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_26641_5 1041826.FCOL_05440 1.43e-42 150.0 COG0270@1|root,COG0270@2|Bacteria,4P351@976|Bacteroidetes,1I9UJ@117743|Flavobacteriia,2NZ0G@237|Flavobacterium 976|Bacteroidetes L C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_26641_7 1609634.A0A0C5ANA6_9VIRU 1.23e-21 95.9 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_142706_3 266265.Bxe_A3103 4.75e-41 140.0 2E04N@1|root,32VT5@2|Bacteria,1N310@1224|Proteobacteria,2W2JF@28216|Betaproteobacteria,1K8RJ@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_233432_2 1416009.V9VEJ1_9CAUD 1.46e-210 615.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_92734_2 1618260.A0A0C5I2C5_9CIRC 3.05e-39 147.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_76242_4 1165094.RINTHH_3920 3.61e-25 105.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_17678_1 247490.KSU1_D0514 2.38e-23 109.0 COG3055@1|root,COG3204@1|root,COG3055@2|Bacteria,COG3204@2|Bacteria 2|Bacteria L pilus organization - - - ko:K02674,ko:K07004 - - - - ko00000,ko02035,ko02044 - - - Big_5,Exo_endo_phos,He_PIG,HemolysinCabind,LTD,Laminin_G_3,Malectin,PA14 k59_241978_2 1609634.A0A0C5AFV4_9VIRU 7.35e-100 306.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_250259_2 1173762.S4TP20_9CAUD 6.8e-29 117.0 4QB3X@10239|Viruses,4QWKP@35237|dsDNA viruses no RNA stage,4QPEE@28883|Caudovirales,4QNCI@10744|Podoviridae 10744|Podoviridae S VWA-like domain (DUF2201) - - - - - - - - - - - - - k59_126243_1 186617.M9M8L2_9VIRU 3.49e-53 182.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_184899_1 1054461.G0XNV0_9CAUD 1.45e-97 353.0 4QAXA@10239|Viruses,4QYJI@35237|dsDNA viruses no RNA stage,4QQ1A@28883|Caudovirales,4QNU7@10744|Podoviridae 10744|Podoviridae S metallopeptidase activity - - - - - - - - - - - - - k59_209493_1 691965.D4P7D6_9CAUD 1.5e-117 375.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_209493_4 411460.RUMTOR_01342 4.22e-27 106.0 28NM4@1|root,2ZBMQ@2|Bacteria,1V1QD@1239|Firmicutes,24G1B@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_35746_1 1234888.K0A2J2_9VIRU 1.3e-39 144.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_226637_3 1120792.JAFV01000001_gene332 1.13e-15 77.8 COG5362@1|root,COG5362@2|Bacteria,1NKZK@1224|Proteobacteria,2U4BJ@28211|Alphaproteobacteria,37076@31993|Methylocystaceae 28211|Alphaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_260050_1 31964.CMS3033 0.000434 46.6 COG2189@1|root,COG2189@2|Bacteria,2I8FH@201174|Actinobacteria,4FQ4A@85023|Microbacteriaceae 201174|Actinobacteria L DNA methylase modB - 2.1.1.72 ko:K00571,ko:K07316 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase,TypeIII_RM_meth k59_3085_4 186617.M9M8L2_9VIRU 1.28e-64 213.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_185016_2 1609634.A0A0C5AFV4_9VIRU 1.81e-52 190.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_127472_1 10752.A0MZD3_BPN4 9.66e-260 741.0 4QGA5@10239|Viruses,4QURD@35237|dsDNA viruses no RNA stage,4QT9N@28883|Caudovirales,4QP47@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_127472_2 10752.A0MZD4_BPN4 1.36e-103 307.0 4QEMD@10239|Viruses,4R0JN@35237|dsDNA viruses no RNA stage,4QUGF@28883|Caudovirales,4QNXF@10744|Podoviridae 10744|Podoviridae S AAA domain - - - - - - - - - - - - - k59_127472_3 1429767.W6ARL0_9CAUD 1.12e-41 150.0 4QH15@10239|Viruses,4QZKH@35237|dsDNA viruses no RNA stage,4QT0Z@28883|Caudovirales,4QP1H@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_127472_4 195253.Syn6312_0894 1.88e-15 75.1 COG0817@1|root,COG0817@2|Bacteria,1G6YP@1117|Cyanobacteria 1117|Cyanobacteria L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group - - - - - - - - - - - - - k59_234327_1 269796.Rru_A3313 3.86e-16 77.8 28IR7@1|root,2Z8QR@2|Bacteria,1PBTP@1224|Proteobacteria,2U248@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_251019_2 1133293.H2EIC0_9CAUD 3.54e-15 85.5 4QAK6@10239|Viruses,4QXWJ@35237|dsDNA viruses no RNA stage,4QPID@28883|Caudovirales 28883|Caudovirales S N-acetylmuramoyl-L-alanine amidase activity - - - - - - - - - - - - - k59_176706_1 1403819.BATR01000081_gene2296 3.09e-21 99.8 COG4675@1|root,COG4675@2|Bacteria 2|Bacteria M tail collar domain protein - - - - - - - - - - - - Collar k59_68980_1 1121459.AQXE01000001_gene2749 5.72e-20 91.7 28IA2@1|root,2Z8CQ@2|Bacteria,1PQM2@1224|Proteobacteria,42Y9U@68525|delta/epsilon subdivisions,2WTUC@28221|Deltaproteobacteria,2MARZ@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_68980_2 935261.JAGL01000009_gene1157 9.07e-14 74.3 2ATMD@1|root,31J5V@2|Bacteria,1RH31@1224|Proteobacteria,2UBNT@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Tail tubular protein - - - - - - - - - - - - Tube k59_68980_4 160488.PP_2282 1.9e-102 311.0 28IR7@1|root,2Z8QR@2|Bacteria,1PBTP@1224|Proteobacteria,1SKTD@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_242986_1 1234888.K0A2J2_9VIRU 2.58e-58 198.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_244080_10 702113.PP1Y_AT3026 2.15e-24 97.1 COG3616@1|root,COG3616@2|Bacteria,1N160@1224|Proteobacteria,2UE7A@28211|Alphaproteobacteria,2K58U@204457|Sphingomonadales 204457|Sphingomonadales E Protein of unknown function (DUF2958) - - - - - - - - - - - - DUF2958 k59_54145_1 1173020.Cha6605_3103 2.5e-11 73.2 COG3864@1|root,COG3864@2|Bacteria,1G20V@1117|Cyanobacteria 1117|Cyanobacteria S metallopeptidase (DUF2201) - - - - - - - - - - - - DUF2201,DUF2201_N k59_54145_3 1476391.X5KCB5_9CAUD 4.25e-56 194.0 4QAR1@10239|Viruses,4QUNA@35237|dsDNA viruses no RNA stage,4QPJE@28883|Caudovirales,4QNDS@10744|Podoviridae 10744|Podoviridae S ATPase activity - - - - - - - - - - - - - k59_19938_1 1906.SFRA_31460 4.82e-12 63.9 2BEJV@1|root,328B9@2|Bacteria,2IRZR@201174|Actinobacteria 201174|Actinobacteria K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA - - - ko:K18955 - - - - ko00000,ko03000 - - - Whib k59_210675_1 156889.Mmc1_1716 7.85e-75 238.0 28NGF@1|root,2ZBII@2|Bacteria,1R9KY@1224|Proteobacteria,2U1P7@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_12113_1 266265.Bxe_A3045 7.37e-08 59.7 COG4675@1|root,COG4675@2|Bacteria,1N2XN@1224|Proteobacteria,2VV00@28216|Betaproteobacteria,1KB9Y@119060|Burkholderiaceae 28216|Betaproteobacteria S tail collar domain protein - - - - - - - - - - - - - k59_203387_1 1411685.U062_00592 4.33e-58 197.0 2EW57@1|root,33PIB@2|Bacteria,1NQQA@1224|Proteobacteria,1SMVX@1236|Gammaproteobacteria,1J7VZ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Phage replication protein CRI - - - - - - - - - - - - Phage_CRI k59_45977_1 626887.J057_01785 2.33e-69 228.0 2DCM2@1|root,32TZV@2|Bacteria,1NAGE@1224|Proteobacteria,1SMRS@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_112431_2 225937.HP15_1959 3.86e-17 84.0 2EFFY@1|root,3398P@2|Bacteria,1NCVZ@1224|Proteobacteria,1SFQ2@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Prophage minor tail protein Z (GPZ) - - - - - - - - - - - - Minor_tail_Z k59_210841_1 438753.AZC_0840 6.71e-43 160.0 COG3170@1|root,COG3170@2|Bacteria,1R69E@1224|Proteobacteria,2U3B9@28211|Alphaproteobacteria 28211|Alphaproteobacteria NU Phage P22-like portal protein - - - - - - - - - - - - - k59_61574_1 1219035.NT2_13_00580 4.62e-26 110.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_45980_1 929556.Solca_1968 8.83e-13 73.6 COG0732@1|root,COG0732@2|Bacteria,4NKMB@976|Bacteroidetes,1IXQM@117747|Sphingobacteriia 976|Bacteroidetes V Type I restriction modification DNA specificity domain - - 3.1.21.3 ko:K01154 - - - - ko00000,ko01000,ko02048 - - - Methylase_S k59_78826_6 935848.JAEN01000011_gene1848 1.98e-07 58.9 COG3409@1|root,COG3409@2|Bacteria,1RAYU@1224|Proteobacteria,2U6D1@28211|Alphaproteobacteria,2PXU7@265|Paracoccus 28211|Alphaproteobacteria M N-acetylmuramidase - - - - - - - - - - - - Muraidase,PG_binding_1 k59_78826_7 691965.D4P7B9_9CAUD 2.58e-29 108.0 4QFDH@10239|Viruses,4QWV5@35237|dsDNA viruses no RNA stage,4QPB8@28883|Caudovirales,4QKNN@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_86232_2 1161935.H9D1D6_9CAUD 5.11e-73 230.0 4QFN8@10239|Viruses,4QYWE@35237|dsDNA viruses no RNA stage,4QS52@28883|Caudovirales,4QP1K@10744|Podoviridae 10744|Podoviridae S metal ion binding - - - - - - - - - - - - - k59_86232_3 1161935.H9D1E3_9CAUD 3.39e-33 131.0 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales,4QNBW@10744|Podoviridae 10744|Podoviridae S DNA helicase activity - - - - - - - - - - - - - k59_61575_1 1114959.SZMC14600_01779 1.55e-15 77.8 COG2227@1|root,COG2227@2|Bacteria,2GMMX@201174|Actinobacteria,4DXPQ@85010|Pseudonocardiales 201174|Actinobacteria H PFAM Methyltransferase domain - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.1.1.222,2.1.1.64 ko:K00568 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04988,R05614,R08769,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11,Methyltransf_23 k59_245359_1 1618242.A0A0C5IBR9_9CIRC 2.73e-44 157.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_172098_1 145579.CAPSD_BPPHM 9.66e-24 103.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_179806_1 305900.GV64_08545 1e-48 177.0 COG0433@1|root,COG0433@2|Bacteria,1QTVP@1224|Proteobacteria,1T1IQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Zonular occludens toxin (Zot) - - - ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko02042 - - - Zot k59_262919_1 2003327.CAPSD_BPCHP 5.76e-22 99.4 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_138843_1 1618237.A0A0C5IMG6_9CIRC 2.4e-13 74.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_47787_2 1150989.H6WXC8_9CAUD 3.87e-91 291.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QM52@10699|Siphoviridae 10699|Siphoviridae S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor - - - - - - - - - - - - - k59_55708_1 945021.TEH_08390 3.85e-07 58.5 COG3935@1|root,COG3935@2|Bacteria,1TPPF@1239|Firmicutes,4HNK6@91061|Bacilli 91061|Bacilli L Psort location Cytoplasmic, score - - - - - - - - - - - - DnaB_2,Phg_2220_C k59_31351_1 745776.DGo_CA1893 2.98e-12 68.6 COG4653@1|root,COG4653@2|Bacteria 2|Bacteria G Phage capsid family xkdG - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_55865_2 471852.Tcur_2031 2.47e-14 73.9 arCOG05626@1|root,30CNA@2|Bacteria,2I38B@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_164123_3 1385658.U5KPZ6_9VIRU 3.51e-134 407.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_156625_4 1192034.CAP_1767 6.02e-124 392.0 COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,42M8J@68525|delta/epsilon subdivisions,2WJD6@28221|Deltaproteobacteria,2YTW8@29|Myxococcales 28221|Deltaproteobacteria L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity recD2 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 k59_63848_1 1197951.I6R0Y7_9CAUD 1.27e-38 145.0 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales 28883|Caudovirales S DnaB-like helicase C terminal domain - - - - - - - - - - - - - k59_56963_2 332101.JIBU02000048_gene3720 4.2e-42 161.0 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,2487V@186801|Clostridia,36EDD@31979|Clostridiaceae 186801|Clostridia L DNA polymerase - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_164125_1 691965.D4P7I3_9CAUD 6.47e-128 399.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_14494_1 1122201.AUAZ01000017_gene2947 3.63e-55 192.0 COG0749@1|root,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,465DD@72275|Alteromonadaceae 1236|Gammaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity - - - - - - - - - - - - DNA_pol_A k59_173650_1 1609634.A0A0C5AFT2_9VIRU 8.31e-36 137.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_181202_1 856793.MICA_1841 4.56e-77 241.0 28HS3@1|root,2Z7ZE@2|Bacteria,1QH9A@1224|Proteobacteria,2TVB0@28211|Alphaproteobacteria,4BR65@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_115705_1 145579.CAPSD_BPPHM 7.52e-76 246.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_115705_5 1986029.Q9MBM3_9VIRU 2.1e-52 180.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_32775_1 1440052.EAKF1_ch1863 7.84e-10 60.8 COG0847@1|root,COG0847@2|Bacteria,1R9YS@1224|Proteobacteria,1S23K@1236|Gammaproteobacteria 1236|Gammaproteobacteria L 3' exoribonuclease, RNase T-like - - - - - - - - - - - - DUF5051 k59_14609_1 1121441.AUCX01000014_gene507 1.36e-15 88.2 COG5563@1|root,COG5563@2|Bacteria,1Q0JE@1224|Proteobacteria,430IH@68525|delta/epsilon subdivisions,2X0GF@28221|Deltaproteobacteria,2MD65@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_140351_1 1692255.A0A0K1RL52_9CIRC 1.42e-62 207.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_115711_1 1458357.BG58_03960 5.13e-25 105.0 COG1216@1|root,COG1216@2|Bacteria,1R554@1224|Proteobacteria,2VKBV@28216|Betaproteobacteria,1K6ER@119060|Burkholderiaceae 28216|Betaproteobacteria S Glycosyl transferase, family 2 - - - - - - - - - - - - - k59_73601_1 691965.D4P7D6_9CAUD 1.49e-21 99.8 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_197056_1 411460.RUMTOR_01335 4e-65 224.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_40877_1 1283078.M1IPN0_9CAUD 4.51e-74 238.0 4QHD0@10239|Viruses,4QXZW@35237|dsDNA viruses no RNA stage,4QUGC@28883|Caudovirales,4QP48@10744|Podoviridae 10744|Podoviridae S T=7 icosahedral viral capsid - - - - - - - - - - - - - k59_214718_1 1385658.U5KPZ6_9VIRU 3.67e-136 409.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_232154_1 279238.Saro_3004 1.03e-73 236.0 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1NKZK@1224|Proteobacteria,2U0EG@28211|Alphaproteobacteria,2KC8R@204457|Sphingomonadales 204457|Sphingomonadales S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6C k59_256382_3 77635.BISU_1950 0.000711 43.9 COG1475@1|root,COG1475@2|Bacteria,2HTYC@201174|Actinobacteria,4D0GC@85004|Bifidobacteriales 201174|Actinobacteria K ParB-like nuclease domain - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_264976_2 145579.REP_BPPHM 1.35e-20 98.6 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_264977_2 1788443.A0A190WHA2_9CIRC 3.47e-06 51.6 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_82667_5 38033.XP_001221915.1 2.8e-07 55.8 COG0445@1|root,KOG2311@2759|Eukaryota,38BWB@33154|Opisthokonta,3NUU9@4751|Fungi,3QJZZ@4890|Ascomycota,211WM@147550|Sordariomycetes,3U4Y1@5139|Sordariales,3HF88@35718|Chaetomiaceae 4751|Fungi J GidA associated domain 3 MTO1 GO:0000166,GO:0000959,GO:0000963,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0030488,GO:0032259,GO:0032543,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043414,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0070525,GO:0070899,GO:0070900,GO:0071704,GO:0090304,GO:0090646,GO:0097159,GO:0140053,GO:1900864,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K03495,ko:K12479 ko04138,ko04144,map04138,map04144 - R08701 RC00053,RC00209,RC00870 ko00000,ko00001,ko03016,ko03036,ko04131 - - - GIDA,GIDA_assoc k59_82667_6 1005395.CSV86_06221 3.35e-20 89.7 2E5K5@1|root,330BC@2|Bacteria,1RG8X@1224|Proteobacteria,1S3Z1@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Siphovirus Gp157 - - - - - - - - - - - - Sipho_Gp157 k59_82667_7 251221.35211274 9.85e-16 79.3 COG4712@1|root,COG4712@2|Bacteria 2|Bacteria S DNA recombination - - - - - - - - - - - - Rad52_Rad22 k59_107152_1 316274.Haur_1384 2.14e-28 117.0 COG4373@1|root,COG4373@2|Bacteria 2|Bacteria - - gp17a - - ko:K06909 - - - - ko00000 - - - Terminase_6,Terminase_6C k59_247753_1 1121935.AQXX01000130_gene2403 4.79e-12 78.2 COG4733@1|root,COG4733@2|Bacteria,1R77Q@1224|Proteobacteria,1S1WT@1236|Gammaproteobacteria,1XMZT@135619|Oceanospirillales 135619|Oceanospirillales D Fibronectin type 3 domain - - - - - - - - - - - - - k59_214740_3 1234888.K0A2J2_9VIRU 2.23e-21 95.9 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_165599_2 1692257.A0A0K1RL39_9CIRC 1.98e-77 245.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_16038_1 1446473.JHWH01000056_gene3653 1.06e-78 246.0 COG5534@1|root,COG5534@2|Bacteria,1MXQ0@1224|Proteobacteria,2TRBV@28211|Alphaproteobacteria,2PW6K@265|Paracoccus 28211|Alphaproteobacteria L Replication initiator protein A repA - - - - - - - - - - - RPA k59_65286_1 1538804.A0A088F7W8_9CAUD 2.08e-108 324.0 4QAR1@10239|Viruses,4QPJE@28883|Caudovirales 28883|Caudovirales S ATPase activity - - - - - - - - - - - - - k59_82673_2 52644.XP_010571021.1 2.88e-14 76.3 KOG2401@1|root,KOG2401@2759|Eukaryota,39R9J@33154|Opisthokonta,3B9DR@33208|Metazoa,3CRA5@33213|Bilateria,489X7@7711|Chordata,4914G@7742|Vertebrata,4GI7B@8782|Aves 33208|Metazoa L NEDD4-binding protein 2-like 2 N4BP2L2 GO:0000122,GO:0001701,GO:0001824,GO:0002682,GO:0002683,GO:0002684,GO:0003674,GO:0003712,GO:0003714,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006355,GO:0006357,GO:0007275,GO:0008150,GO:0008284,GO:0009790,GO:0009792,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017053,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032501,GO:0032502,GO:0032991,GO:0042127,GO:0043009,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045595,GO:0045596,GO:0045892,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048856,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0051094,GO:0051171,GO:0051172,GO:0051239,GO:0051240,GO:0051241,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0072091,GO:0080090,GO:0140110,GO:1901532,GO:1901533,GO:1902033,GO:1902035,GO:1902036,GO:1902037,GO:1902679,GO:1903506,GO:1903507,GO:1903706,GO:1903707,GO:1903708,GO:2000026,GO:2000112,GO:2000113,GO:2000648,GO:2000736,GO:2000737,GO:2001141 - - - - - - - - - - AAA_33,Smr k59_98531_1 691965.D4P7I3_9CAUD 7.3e-49 176.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_165761_3 1692244.A0A0K1RLR5_9CIRC 1.36e-40 149.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_256636_1 1609634.A0A0C5ANA6_9VIRU 0.000696 47.4 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_239811_1 1609634.A0A0C5AFT2_9VIRU 8.53e-17 79.3 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_232751_2 1454010.JEOE01000073_gene2 4.7e-48 164.0 2DP06@1|root,33008@2|Bacteria,2GTMC@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_50259_1 568816.Acin_1346 5.88e-19 92.0 COG1372@1|root,COG4626@1|root,COG1372@2|Bacteria,COG4626@2|Bacteria,1TPU1@1239|Firmicutes,4H4UG@909932|Negativicutes 909932|Negativicutes L LAGLIDADG-like domain - - - - - - - - - - - - LAGLIDADG_3,Terminase_1 k59_25494_1 666509.RCA23_c04080 3.63e-17 89.7 COG1199@1|root,COG3378@1|root,COG1199@2|Bacteria,COG3378@2|Bacteria,1MYGF@1224|Proteobacteria,2TTNY@28211|Alphaproteobacteria 28211|Alphaproteobacteria KL Phage plasmid primase, P4 family domain protein - - - ko:K06919 - - - - ko00000 - - - Prim-Pol,Toprim_3 k59_25494_3 1208583.COMX_09536 1.68e-05 52.0 COG5352@1|root,COG5352@2|Bacteria,1RHI6@1224|Proteobacteria,2TS7F@28211|Alphaproteobacteria,2JU3J@204441|Rhodospirillales 204441|Rhodospirillales S GcrA cell cycle regulator - - - ko:K13583 ko04112,map04112 - - - ko00000,ko00001 - - - GcrA k59_25494_6 187303.BN69_1626 1.12e-09 68.2 COG1475@1|root,COG4725@1|root,COG1475@2|Bacteria,COG4725@2|Bacteria,1R553@1224|Proteobacteria,2TRP6@28211|Alphaproteobacteria,36XZ4@31993|Methylocystaceae 28211|Alphaproteobacteria KT MT-A70 - - - - - - - - - - - - MT-A70,ParBc k59_116662_2 1634485.A0A0E3JN85_9VIRU 6.25e-56 182.0 4QB6C@10239|Viruses 10239|Viruses L Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_602_1 1120963.KB894518_gene2791 1.45e-33 132.0 COG0553@1|root,COG0553@2|Bacteria,1MV6M@1224|Proteobacteria,1RQ34@1236|Gammaproteobacteria,2PZF9@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria L COG0553 Superfamily II DNA RNA helicases, SNF2 family - - - - - - - - - - - - Helicase_C,Mrr_cat,SNF2_N,SWIM k59_33914_1 1609634.A0A0C5AFV4_9VIRU 1.08e-57 196.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_50391_2 322855.Q52PS6_9CAUD 3.18e-18 86.7 4QAKM@10239|Viruses,4QPEF@28883|Caudovirales 28883|Caudovirales S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_232863_2 715226.ABI_16440 1.01e-41 146.0 COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,2TQSB@28211|Alphaproteobacteria,2KFFT@204458|Caulobacterales 204458|Caulobacterales F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA - 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt k59_58645_1 1128073.G9LQV6_9CIRC 1.16e-20 95.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_58645_3 1618247.A0A0C5I2K0_9CIRC 3.36e-21 94.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_232867_1 2003327.CAPSD_BPCHP 1.91e-31 123.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_216356_1 1618248.A0A0C5IB82_9CIRC 3.37e-20 94.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_126217_1 1219035.NT2_13_00580 7.49e-79 249.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_109368_2 1618248.A0A0C5IB82_9CIRC 1.32e-15 82.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_258961_3 484019.THA_419 4.32e-21 95.1 COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2GCTF@200918|Thermotogae 200918|Thermotogae M peptidase - - - - - - - - - - - - LysM,Peptidase_M23 k59_217661_3 1457393.AZ09_10555 9.12e-34 124.0 2CJW6@1|root,32SAX@2|Bacteria,1N3WF@1224|Proteobacteria,2USGV@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_51446_1 484022.Fphi_1619 2.83e-75 243.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,1RMPV@1236|Gammaproteobacteria,4606X@72273|Thiotrichales 72273|Thiotrichales F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdA - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN k59_167599_2 1449351.RISW2_03825 6.09e-22 91.7 COG3750@1|root,COG3750@2|Bacteria,1N77J@1224|Proteobacteria,2UFX6@28211|Alphaproteobacteria,4KP04@93682|Roseivivax 28211|Alphaproteobacteria S COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins - - - - - - - - - - - - DUF2312 k59_51450_1 1609634.A0A0C5AFV4_9VIRU 1.03e-69 230.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_9717_1 388739.RSK20926_15466 6.82e-34 134.0 2F01Z@1|root,33T5S@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_17772_1 691965.D4P7E6_9CAUD 8.16e-129 426.0 4QAK6@10239|Viruses,4R01K@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_200547_1 552398.HMPREF0866_01604 9.98e-44 162.0 COG5280@1|root,COG5280@2|Bacteria,1UJ98@1239|Firmicutes,24BN7@186801|Clostridia,3WSR4@541000|Ruminococcaceae 186801|Clostridia S Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_127728_3 1347393.HG726022_gene3591 8.82e-13 70.9 2AFCI@1|root,315C5@2|Bacteria,4PJJ2@976|Bacteroidetes,2FS4G@200643|Bacteroidia,4AQI0@815|Bacteroidaceae 976|Bacteroidetes S KilA-N domain - - - - - - - - - - - - KilA-N k59_10814_2 44088.Q6VZJ4_CNPV 1.84e-08 56.2 4QB1C@10239|Viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_35957_1 1506572.A0A097ZPG0_9CIRC 2.83e-14 74.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_35957_3 1692250.A0A0K1RLR1_9CIRC 9.43e-10 60.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_3324_1 388739.RSK20926_08742 6.33e-09 55.8 2DN11@1|root,32UU2@2|Bacteria,1NATN@1224|Proteobacteria,2UDMR@28211|Alphaproteobacteria 28211|Alphaproteobacteria S K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - - - - - - - - - - - k59_135882_5 595460.RRSWK_03642 2.77e-29 131.0 2DME6@1|root,32QWJ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_119449_1 1385658.U5KPZ6_9VIRU 1.48e-61 207.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_85237_1 665956.HMPREF1032_00647 6.11e-29 119.0 2EWZQ@1|root,33QB0@2|Bacteria,1V0T1@1239|Firmicutes,249Z2@186801|Clostridia,3WNBH@541000|Ruminococcaceae 186801|Clostridia S DNA polymerase type-B family - - - - - - - - - - - - - k59_111098_1 1082932.ATCR1_06771 9.13e-20 87.8 28NGF@1|root,2ZBII@2|Bacteria,1R9KY@1224|Proteobacteria,2U1P7@28211|Alphaproteobacteria,4B747@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_202025_2 1692252.A0A0K1RL35_9CIRC 3.89e-45 163.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_5023_8 2880.D8LIE4 3.57e-43 170.0 COG1061@1|root,2QT4U@2759|Eukaryota 2759|Eukaryota KL DEAD DEAH box helicase irc3 GO:0000002,GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005739,GO:0005759,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0007005,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010467,GO:0010501,GO:0016043,GO:0016070,GO:0016072,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022613,GO:0031974,GO:0031981,GO:0032042,GO:0033676,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042623,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070035,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 - ko:K17677 - - - - ko00000,ko01000,ko03029 - - - Helicase_C,ResIII k59_5023_10 906668.G8C7L3_9CAUD 1.97e-23 100.0 4QBX9@10239|Viruses,4QWQQ@35237|dsDNA viruses no RNA stage,4QPDR@28883|Caudovirales,4QKZW@10699|Siphoviridae 10699|Siphoviridae S Rad52/22 family double-strand break repair protein - - - - - - - - - - - - - k59_46078_1 1609634.A0A0C5AFT2_9VIRU 3.78e-79 248.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_161587_1 1234888.K0A2J2_9VIRU 1.57e-44 162.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_194422_1 1028800.RG540_CH13880 7.66e-07 50.1 28IA2@1|root,2Z8CQ@2|Bacteria,1PQM2@1224|Proteobacteria,2TUAP@28211|Alphaproteobacteria,4BJ6C@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_194422_2 756276.A0A096VKL9_9VIRU 5.2e-21 94.4 4QBMX@10239|Viruses,4QV9I@35237|dsDNA viruses no RNA stage 10239|Viruses S Pfam:Tube - GO:0005575,GO:0019012 - - - - - - - - - - - k59_244256_2 1618260.A0A0C5I2C5_9CIRC 2.79e-42 155.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_54384_2 1609634.A0A0C5AFT2_9VIRU 3.73e-137 399.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_252474_2 46681.XP_001738227.1 1.28e-05 54.3 2CSEE@1|root,2RBK2@2759|Eukaryota,3X9MH@554915|Amoebozoa 554915|Amoebozoa G RNA helicase - - - - - - - - - - - - RNA_helicase k59_221020_1 742740.HMPREF9474_02299 4.68e-58 195.0 COG0553@1|root,COG0553@2|Bacteria,1TS9W@1239|Firmicutes,24CGX@186801|Clostridia,222GT@1506553|Lachnoclostridium 186801|Clostridia KL Helicase conserved C-terminal domain - - - - - - - - - - - - - k59_203501_1 926569.ANT_30770 1.05e-41 161.0 COG4397@1|root,COG4397@2|Bacteria 2|Bacteria S Mu-like prophage major head subunit gpT - - - - - - - - - - - - Mu-like_gpT,Peptidase_S78 k59_54385_1 1042375.AFPL01000014_gene2229 9.73e-100 310.0 COG5525@1|root,COG5525@2|Bacteria,1MVS3@1224|Proteobacteria,1RRH5@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Terminase - - - - - - - - - - - - Terminase_GpA k59_170609_1 1385658.U5KPZ6_9VIRU 4.5e-111 340.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_103603_2 211165.AJLN01000060_gene3848 6.81e-21 96.7 COG0270@1|root,COG0270@2|Bacteria,1G8NG@1117|Cyanobacteria 1117|Cyanobacteria L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_86310_2 323097.Nham_3328 1.98e-58 209.0 COG5301@1|root,COG5301@2|Bacteria,1N6XX@1224|Proteobacteria,2USJX@28211|Alphaproteobacteria 28211|Alphaproteobacteria G cellulose 1,4-beta-cellobiosidase activity - - - - - - - - - - - - - k59_86310_7 716541.ECL_02843 3.61e-26 100.0 COG3179@1|root,COG3179@2|Bacteria,1RE8K@1224|Proteobacteria,1S4U8@1236|Gammaproteobacteria 1236|Gammaproteobacteria S D-alanyl-D-alanine carboxypeptidase - - - - - - - - - - - - Peptidase_M15_4 k59_80097_4 1121943.KB900008_gene1990 7.14e-08 55.5 2ER6M@1|root,33IS8@2|Bacteria,1NIM1@1224|Proteobacteria,1SU18@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_80097_5 1249627.D779_2292 7.93e-32 128.0 COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,1R97W@1224|Proteobacteria,1TK9M@1236|Gammaproteobacteria,1X0PG@135613|Chromatiales 135613|Chromatiales D Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_262958_1 935948.KE386495_gene1179 2.85e-05 53.1 COG1280@1|root,COG5283@1|root,COG1280@2|Bacteria,COG5283@2|Bacteria,1UKMJ@1239|Firmicutes,25FZC@186801|Clostridia 186801|Clostridia E lysine exporter protein (LysE YggA) - - - - - - - - - - - - - k59_245392_1 1303692.SFUL_553 7.86e-08 54.3 2DMIE@1|root,32RSG@2|Bacteria,2IQEH@201174|Actinobacteria 201174|Actinobacteria K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA - - - ko:K18955 - - - - ko00000,ko03000 - - - Whib k59_6679_1 693746.OBV_28450 1.77e-06 57.8 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia,2N6XB@216572|Oscillospiraceae 186801|Clostridia L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_105174_2 596154.Alide2_4807 9.13e-08 59.7 COG1475@1|root,COG1475@2|Bacteria,1N87M@1224|Proteobacteria 1224|Proteobacteria K ParB-like nuclease domain - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_222864_1 1122138.AQUZ01000143_gene7945 9.91e-09 58.2 COG1783@1|root,COG1783@2|Bacteria 2|Bacteria S DNA packaging - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_6 k59_222864_2 652103.Rpdx1_2520 1.7e-70 253.0 COG2268@1|root,COG2268@2|Bacteria,1NT13@1224|Proteobacteria,2U335@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Band 7 protein - - - - - - - - - - - - - k59_163040_2 438753.AZC_3588 3.2e-122 375.0 28MSK@1|root,2ZB0X@2|Bacteria,1R7CY@1224|Proteobacteria,2U2MY@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_163040_4 151528.L0CNX3_9CAUD 1.45e-12 74.3 4QBAU@10239|Viruses,4QW8E@35237|dsDNA viruses no RNA stage,4QPEP@28883|Caudovirales 28883|Caudovirales S Phage T7 capsid assembly protein - - - - - - - - - - - - - k59_163040_7 1121459.AQXE01000001_gene2751 2.95e-125 368.0 28IR7@1|root,2Z8QR@2|Bacteria,1PBTP@1224|Proteobacteria,42Z7V@68525|delta/epsilon subdivisions,2WTZ3@28221|Deltaproteobacteria,2M8NA@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_163040_8 563192.HMPREF0179_03435 2.81e-34 127.0 2ATMD@1|root,31J5V@2|Bacteria,1RH31@1224|Proteobacteria,42YF2@68525|delta/epsilon subdivisions,2WTJ2@28221|Deltaproteobacteria,2MC98@213115|Desulfovibrionales 28221|Deltaproteobacteria S Tail tubular protein - - - - - - - - - - - - Tube k59_163040_9 438753.AZC_3583 3.22e-13 69.3 28IA2@1|root,2Z8CQ@2|Bacteria,1PQM2@1224|Proteobacteria,2TUAP@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_114409_1 1328313.DS2_13254 0.000126 52.4 COG1404@1|root,COG2931@1|root,COG3210@1|root,COG4932@1|root,COG5295@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4932@2|Bacteria,COG5295@2|Bacteria,1MU7T@1224|Proteobacteria 1224|Proteobacteria Q COG2931, RTX toxins and related Ca2 -binding proteins - - - - - - - - - - - - Cadherin,HemolysinCabind k59_114409_6 1445859.W6E9J9_9CAUD 5.28e-27 103.0 4QB6G@10239|Viruses,4QVYX@35237|dsDNA viruses no RNA stage,4QQS8@28883|Caudovirales 28883|Caudovirales S Peptidase M15 - - - - - - - - - - - - - k59_114409_7 1248917.ANFX01000037_gene2114 2.1e-41 141.0 2C69U@1|root,32STX@2|Bacteria,1RDUC@1224|Proteobacteria,2U7XY@28211|Alphaproteobacteria,2K4F1@204457|Sphingomonadales 204457|Sphingomonadales S Holin of 3TMs, for gene-transfer release - - - - - - - - - - - - GTA_holin_3TM k59_147929_3 857087.Metme_1048 1.62e-12 62.4 28Y49@1|root,2ZJZR@2|Bacteria,1P5YK@1224|Proteobacteria,1STPP@1236|Gammaproteobacteria,1XGUS@135618|Methylococcales 135618|Methylococcales - - - - - - - - - - - - - - - k59_47965_2 942016.E9NIH0_9CAUD 7.33e-58 200.0 4QGA5@10239|Viruses,4QURD@35237|dsDNA viruses no RNA stage,4QT9N@28883|Caudovirales,4QP47@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_237031_1 1237149.C900_04204 1.1e-11 66.6 COG3291@1|root,COG4099@1|root,COG4932@1|root,COG3291@2|Bacteria,COG4099@2|Bacteria,COG4932@2|Bacteria,4NP7H@976|Bacteroidetes,47XCB@768503|Cytophagia 976|Bacteroidetes M Immunoglobulin like - - - - - - - - - - - - - k59_6848_1 1105367.CG50_10605 2.83e-12 76.3 COG2304@1|root,COG2304@2|Bacteria,1QWI7@1224|Proteobacteria,2TY8F@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Putative phage tail protein - - - - - - - - - - - - Phage-tail_3,VWA k59_87534_1 1089439.KB902274_gene1883 1.86e-09 62.4 COG2974@1|root,COG2974@2|Bacteria,1MXPR@1224|Proteobacteria,1RMNN@1236|Gammaproteobacteria,462C8@72273|Thiotrichales 72273|Thiotrichales L May be involved in recombination rdgC - - ko:K03554 - - - - ko00000,ko03400 - - - RdgC k59_87534_2 1209072.ALBT01000058_gene828 1.67e-70 222.0 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria,1FH39@10|Cellvibrio 1236|Gammaproteobacteria L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_87534_4 1122243.KB903782_gene330 6.13e-25 97.8 COG1551@1|root,COG1551@2|Bacteria,1N6PG@1224|Proteobacteria,1SCB4@1236|Gammaproteobacteria,3NNX1@468|Moraxellaceae 1236|Gammaproteobacteria T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding csrA GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005979,GO:0006109,GO:0006139,GO:0006417,GO:0006446,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0010675,GO:0010677,GO:0010906,GO:0010962,GO:0016070,GO:0016071,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032881,GO:0032885,GO:0034248,GO:0034249,GO:0034641,GO:0043170,GO:0043255,GO:0043467,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045719,GO:0045912,GO:0045947,GO:0046483,GO:0048027,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0062012,GO:0065007,GO:0070873,GO:0070874,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:2000112,GO:2000113 - ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 - - - ko00000,ko00001,ko03019 - - - CsrA k59_164802_1 29730.Gorai.013G001200.1 0.000404 51.2 COG0553@1|root,KOG1001@2759|Eukaryota,37IVF@33090|Viridiplantae,3G7HD@35493|Streptophyta 35493|Streptophyta KL SWI SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3-like - - 2.3.2.27 ko:K15711 - - - - ko00000,ko01000,ko03400,ko04121 - - - HIRAN,Helicase_C,SNF2_N,zf-C3HC4,zf-C3HC4_3 k59_88651_1 1266845.Q783_03235 1.31e-07 59.3 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,4H9S7@91061|Bacilli,27FQ5@186828|Carnobacteriaceae 91061|Bacilli L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A k59_88652_1 1192868.CAIU01000008_gene938 2.85e-42 153.0 COG0553@1|root,COG0553@2|Bacteria,1R7CK@1224|Proteobacteria,2U228@28211|Alphaproteobacteria,43I7K@69277|Phyllobacteriaceae 28211|Alphaproteobacteria KL DEAD-like helicases superfamily - - - - - - - - - - - - Helicase_C,N6_N4_Mtase k59_15087_1 1121097.JCM15093_3233 1.56e-57 194.0 COG0863@1|root,COG0863@2|Bacteria,4PMGB@976|Bacteroidetes,2G0C7@200643|Bacteroidia,4APG6@815|Bacteroidaceae 976|Bacteroidetes L Belongs to the N(4) N(6)-methyltransferase family - - - - - - - - - - - - - k59_74029_8 1463901.JOIY01000001_gene4831 5.02e-05 46.6 COG0542@1|root,COG0542@2|Bacteria,2GKKF@201174|Actinobacteria 201174|Actinobacteria O Pfam Clp clpC2 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Clp_N k59_197561_1 1692255.A0A0K1RL52_9CIRC 1.46e-91 281.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_140811_1 1692254.A0A0K1RLS2_9CIRC 0.000143 50.8 4QB6C@10239|Viruses,4QUKM@29258|ssDNA viruses 10239|Viruses J Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_74034_1 1229172.JQFA01000002_gene4647 2.62e-05 55.5 COG4942@1|root,COG4942@2|Bacteria,1G2JU@1117|Cyanobacteria,1H7G0@1150|Oscillatoriales 1117|Cyanobacteria D PFAM Peptidase family M23 - - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M23 k59_264806_1 1041142.ATTP01000043_gene5324 2.65e-05 48.9 28JWE@1|root,2Z9M6@2|Bacteria,1R76R@1224|Proteobacteria,2U0BP@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_190716_2 1410618.JNKI01000026_gene1984 2.14e-05 54.3 COG0791@1|root,COG3409@1|root,COG0791@2|Bacteria,COG3409@2|Bacteria,1V9ZW@1239|Firmicutes,4H3PF@909932|Negativicutes 909932|Negativicutes M NlpC P60 family protein lytE - - - - - - - - - - - NLPC_P60,PG_binding_1 k59_132552_4 469381.Dpep_0394 6.75e-26 103.0 COG0817@1|root,COG0817@2|Bacteria,3TCBE@508458|Synergistetes 508458|Synergistetes L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group - - - - - - - - - - - - - k59_23563_2 1038860.AXAP01000015_gene2006 1.33e-28 117.0 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,2U6BJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S TIGRFAM phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_157209_1 1112209.AHVZ01000009_gene2687 1.26e-115 357.0 COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,1RM8Y@1236|Gammaproteobacteria,3NIYH@468|Moraxellaceae 1236|Gammaproteobacteria Q FtsX-like permease family ybbP - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX k59_99157_3 444861.E3SPQ9_9CAUD 2.14e-30 111.0 4QG13@10239|Viruses,4QVBE@35237|dsDNA viruses no RNA stage,4QSEQ@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_99157_5 1353531.AZNX01000020_gene4384 7.86e-34 125.0 2A4D4@1|root,30SYX@2|Bacteria,1PCIM@1224|Proteobacteria,2USSQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_99157_6 1353531.AZNX01000042_gene4044 3.57e-56 181.0 COG1738@1|root,COG1738@2|Bacteria,1RDSF@1224|Proteobacteria 1224|Proteobacteria S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage - - - ko:K09125 - - - - ko00000 - - - Vut_1 k59_265171_2 1788445.A0A190WHA3_9CIRC 3.65e-53 181.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_248776_2 1192868.CAIU01000008_gene927 1.54e-84 268.0 COG1783@1|root,COG1783@2|Bacteria,1PE12@1224|Proteobacteria,2V9EC@28211|Alphaproteobacteria,43QJZ@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Mu-like prophage FluMu protein gp28 - - - - - - - - - - - - - k59_248778_2 521000.PROVRETT_05530 1.89e-21 89.0 COG3179@1|root,COG3179@2|Bacteria,1RE8K@1224|Proteobacteria,1S4U8@1236|Gammaproteobacteria,3Z9BP@586|Providencia 1236|Gammaproteobacteria S D-alanyl-D-alanine carboxypeptidase - - - - - - - - - - - - Peptidase_M15_4 k59_248778_8 1072685.IX83_07200 5.37e-26 106.0 2DIG9@1|root,3036R@2|Bacteria,1RBPA@1224|Proteobacteria,2WH3R@28216|Betaproteobacteria,3T9JP@506|Alcaligenaceae 28216|Betaproteobacteria L YqaJ-like viral recombinase domain - - 3.1.11.3 ko:K01143 - - - - ko00000,ko01000 - - - YqaJ k59_265182_1 1692252.A0A0K1RL35_9CIRC 4.95e-11 69.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_265182_2 1475143.W8SNN0_9CIRC 9.99e-11 62.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_90517_1 1123057.P872_11820 9.25e-19 87.0 2E74C@1|root,331NT@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Methyltransf_11,Methyltransf_31 k59_59093_7 1609634.A0A0C5AFT2_9VIRU 1.15e-11 70.1 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_167072_1 1548903.A0A0A1IWQ8_9CAUD 2.25e-53 177.0 4QAIK@10239|Viruses,4QPEB@28883|Caudovirales 28883|Caudovirales S phosphoprotein phosphatase activity - - - - - - - - - - - - - k59_241507_1 186617.M9M8L2_9VIRU 9.78e-163 473.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_241507_5 1609634.A0A0C5ANA6_9VIRU 8.31e-17 83.6 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_125656_2 1204521.I7A8M4_9CAUD 3.69e-08 60.8 4QCW5@10239|Viruses,4QWI1@35237|dsDNA viruses no RNA stage,4QQVP@28883|Caudovirales,4QHUS@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_249830_1 1618248.A0A0C5IB82_9CIRC 5.62e-45 158.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_249830_2 1692242.A0A0K1RKZ2_9CIRC 1.13e-24 107.0 4QFEW@10239|Viruses,4QUKZ@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_1360_3 1385658.U5KPZ6_9VIRU 2.1e-165 483.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_67437_1 1379725.S5TMY9_9CIRC 4.29e-32 133.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_183509_4 10732.K4HYT8_9CAUD 8.75e-30 119.0 4QGJD@10239|Viruses,4R0CG@35237|dsDNA viruses no RNA stage,4QU69@28883|Caudovirales,4QKQQ@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_183509_6 1157635.KB892046_gene5805 8.4e-59 211.0 COG0749@1|root,COG0749@2|Bacteria,2I975@201174|Actinobacteria 201174|Actinobacteria L COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains - - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - DNA_pol_A,DNA_pol_A_exo1 k59_17427_2 645099.MREP_BBTVA 3.24e-56 191.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_100623_1 1051675.G0YQC3_9CAUD 6.01e-16 82.4 4QBMV@10239|Viruses,4QUU6@35237|dsDNA viruses no RNA stage,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_1362_1 1385658.U5KNR1_9VIRU 4.45e-44 155.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_134009_1 440250.A5HL24_9CAUD 4.05e-44 175.0 4QGKB@10239|Viruses,4QZ0P@35237|dsDNA viruses no RNA stage,4QSXQ@28883|Caudovirales,4QNSQ@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_117399_4 243275.TDE_1157 4.68e-81 261.0 COG1783@1|root,COG1783@2|Bacteria 2|Bacteria S DNA packaging - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_6 k59_51020_1 1247024.JRLH01000010_gene1213 3.45e-08 60.1 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria 1236|Gammaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_42742_1 1692252.A0A0K1RL35_9CIRC 4.75e-64 207.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_42742_3 1692252.A0A0K1RL35_9CIRC 2.12e-22 94.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_192430_1 1071679.BG57_04755 1.82e-07 57.4 COG1573@1|root,COG1573@2|Bacteria,1MW8T@1224|Proteobacteria,2VMTJ@28216|Betaproteobacteria,1K5A3@119060|Burkholderiaceae 28216|Betaproteobacteria L PFAM Uracil-DNA glycosylase superfamily - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - DUF4130,UDG k59_201099_1 1618254.A0A0C5IBG4_9CIRC 1.41e-45 157.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_201099_3 1618254.A0A0C5IBG4_9CIRC 3.73e-58 187.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_135042_1 865938.Weevi_0254 1.27e-11 69.7 COG1783@1|root,COG1783@2|Bacteria,4P9P0@976|Bacteroidetes,1I733@117743|Flavobacteriia 976|Bacteroidetes S Phage terminase large subunit - - - ko:K06909 - - - - ko00000 - - - Terminase_3 k59_59922_1 1219035.NT2_13_00600 2.13e-16 79.3 290X3@1|root,2ZNIW@2|Bacteria,1P7TA@1224|Proteobacteria,2UXFQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_52041_1 1609634.A0A0C5AFV4_9VIRU 5.39e-115 346.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_159503_4 1248232.BANQ01000052_gene2865 5.51e-42 159.0 2CDPS@1|root,2ZBQT@2|Bacteria,1RB59@1224|Proteobacteria,1S2U0@1236|Gammaproteobacteria,1XW3J@135623|Vibrionales 135623|Vibrionales S Phage replication protein CRI - - - - - - - - - - - - Phage_CRI,Phage_X k59_159503_5 1215092.PA6_046_00270 7.48e-19 78.6 28QDM@1|root,2ZCVZ@2|Bacteria,1P5MR@1224|Proteobacteria,1SW6Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_159503_6 1397528.Q671_14285 9.58e-94 292.0 COG4128@1|root,COG4128@2|Bacteria,1REHG@1224|Proteobacteria,1S491@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Zonular occludens toxin (Zot) - - - - - - - - - - - - Zot k59_250667_1 307480.IW16_06245 3.19e-53 175.0 COG3409@1|root,COG3409@2|Bacteria,4NFKN@976|Bacteroidetes,1HWSX@117743|Flavobacteriia,3ZRFD@59732|Chryseobacterium 976|Bacteroidetes M N-acetylmuramidase - - - - - - - - - - - - Muraidase k59_52179_1 1538644.KO02_16250 1.62e-21 92.0 COG0467@1|root,COG0467@2|Bacteria,4PKD7@976|Bacteroidetes 976|Bacteroidetes T Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction - - - - - - - - - - - - AAA k59_52179_2 1347342.BN863_28970 9.55e-84 257.0 COG2842@1|root,COG2842@2|Bacteria,4NNEH@976|Bacteroidetes,1IIBS@117743|Flavobacteriia 976|Bacteroidetes S AAA domain - - 3.6.1.3 ko:K07132 - - - - ko00000,ko01000 - - - AAA_22 k59_68495_1 1385658.U5KPZ6_9VIRU 2.34e-68 226.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_259585_2 1157708.KB907451_gene5046 2.19e-38 142.0 COG0616@1|root,COG0616@2|Bacteria,1QGPW@1224|Proteobacteria,2VJ0N@28216|Betaproteobacteria,4AB1E@80864|Comamonadaceae 28216|Betaproteobacteria OU PFAM peptidase S49 - - - - - - - - - - - - Peptidase_S49 k59_27434_6 857293.CAAU_0781 8.87e-84 267.0 COG3723@1|root,COG3723@2|Bacteria,1UNDF@1239|Firmicutes,24ECD@186801|Clostridia,36HN4@31979|Clostridiaceae 186801|Clostridia L RecT family - - - ko:K07455 - - - - ko00000,ko03400 - - - RecT k59_27434_7 749222.Nitsa_1823 4.95e-17 88.2 COG0270@1|root,COG0270@2|Bacteria,1N0XD@1224|Proteobacteria 1224|Proteobacteria H C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_126954_1 1618248.A0A0C5IB82_9CIRC 2.91e-14 79.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_68498_1 2003327.CAPSD_BPCHP 4.86e-16 82.8 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_259587_1 1401067.HMPREF0872_06875 2.94e-18 91.3 COG2887@1|root,COG2887@2|Bacteria,1TPIC@1239|Firmicutes,4H2UC@909932|Negativicutes 909932|Negativicutes L Psort location Cytoplasmic, score 8.96 - - - - - - - - - - - - DUF2800 k59_2642_1 95619.PM1_0217770 1.49e-24 104.0 COG3566@1|root,COG3566@2|Bacteria,1QWCX@1224|Proteobacteria,1RZS8@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - DUF2213 k59_118886_1 596153.Alide_1641 4.57e-13 72.0 2EKAP@1|root,33E0Y@2|Bacteria,1NAAI@1224|Proteobacteria,2VZTN@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_77024_1 1234881.K0A1K7_9CIRC 6.28e-22 94.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_18389_2 913970.F8RW84_9VIRU 7.36e-19 93.2 4QCVK@10239|Viruses,4QUMV@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_145487_3 69279.BG36_21015 2.76e-52 176.0 COG3206@1|root,COG3206@2|Bacteria,1ND5H@1224|Proteobacteria,2UIQZ@28211|Alphaproteobacteria,43P6G@69277|Phyllobacteriaceae 28211|Alphaproteobacteria M protein involved in exopolysaccharide biosynthesis - - - - - - - - - - - - - k59_111982_2 690850.Desaf_2087 9.02e-13 70.5 COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,42QXV@68525|delta/epsilon subdivisions,2WMXB@28221|Deltaproteobacteria,2MF4J@213115|Desulfovibrionales 28221|Deltaproteobacteria L Uracil DNA glycosylase superfamily - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k59_70134_8 1089552.KI911559_gene3374 5.07e-94 285.0 28HS3@1|root,2Z7ZE@2|Bacteria,1QH9A@1224|Proteobacteria,2TVB0@28211|Alphaproteobacteria,2JPPD@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - k59_11700_1 1215092.PA6_009_00130 0.00054 50.4 COG0454@1|root,COG0503@1|root,COG1040@1|root,COG0456@2|Bacteria,COG0503@2|Bacteria,COG1040@2|Bacteria,1QV41@1224|Proteobacteria,1SZB6@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis - - - - - - - - - - - - - k59_103242_1 1609634.A0A0C5AFT2_9VIRU 1.25e-104 313.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_145604_2 760568.Desku_1126 6.62e-62 212.0 COG1475@1|root,COG4725@1|root,COG1475@2|Bacteria,COG4725@2|Bacteria,1TT7N@1239|Firmicutes,24D10@186801|Clostridia 186801|Clostridia L ParB-like nuclease domain - - - - - - - - - - - - ParBc k59_161230_1 1122201.AUAZ01000021_gene3147 2.27e-46 162.0 COG1783@1|root,COG1783@2|Bacteria 2|Bacteria S DNA packaging - - - ko:K06909 - - - - ko00000 - - - Terminase_3 k59_161230_2 1358423.N180_02820 4.36e-06 50.4 2E8S0@1|root,3332X@2|Bacteria,4NWIA@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - k59_235371_1 398580.Dshi_1907 1.94e-08 59.3 COG4951@1|root,COG4951@2|Bacteria 2|Bacteria - - XK27_08510 - - ko:K06919 - - - - ko00000 - - - DUF1882,Helicase_C,ResIII k59_4680_1 697281.Mahau_2914 9.82e-29 119.0 COG4695@1|root,COG4695@2|Bacteria,1TP8B@1239|Firmicutes,2497C@186801|Clostridia,42FVH@68295|Thermoanaerobacterales 186801|Clostridia S TIGRFAM phage portal protein, HK97 family - - - - - - - - - - - - Phage_Mu_F,Phage_portal k59_130470_7 1500301.JQMF01000006_gene1755 1.94e-155 461.0 28MSK@1|root,2ZB0X@2|Bacteria,1R7CY@1224|Proteobacteria,2U2MY@28211|Alphaproteobacteria,4BJ92@82115|Rhizobiaceae 28211|Alphaproteobacteria S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_171693_2 1618241.A0A0C5I2I4_9CIRC 5.09e-107 322.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_262732_1 1165094.RINTHH_3920 3.37e-54 184.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_262732_2 145579.C_BPPHM 4.28e-10 58.2 4QCC5@10239|Viruses,4QUKW@29258|ssDNA viruses,4QP4C@10841|Microviridae 10841|Microviridae S viral process - - - - - - - - - - - - - k59_195549_1 1195075.I6RTW5_9CAUD 8.31e-115 349.0 4QHE5@10239|Viruses,4QW3G@35237|dsDNA viruses no RNA stage,4QPFG@28883|Caudovirales,4QMK7@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_204836_1 698440.XP_007288703.1 3.28e-26 117.0 COG5108@1|root,KOG1038@2759|Eukaryota,38EAY@33154|Opisthokonta,3NU1C@4751|Fungi,3QN4S@4890|Ascomycota,20VE3@147548|Leotiomycetes 4751|Fungi KL DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates RPO41 GO:0000002,GO:0000428,GO:0000959,GO:0001018,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006351,GO:0006390,GO:0006725,GO:0006807,GO:0006996,GO:0007005,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0031974,GO:0032774,GO:0032991,GO:0034062,GO:0034245,GO:0034641,GO:0034645,GO:0034654,GO:0042645,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0061695,GO:0070013,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097659,GO:0097747,GO:0098798,GO:0140053,GO:0140098,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K10908 - - - - ko00000,ko01000,ko03029 - - - RNA_pol,RPOL_N k59_21145_2 1986029.Q9MBM3_9VIRU 1.08e-64 212.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_21145_4 1385658.U5KPZ6_9VIRU 5.55e-74 239.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_87326_1 1458357.BG58_11025 8.37e-12 65.1 COG2197@1|root,COG2197@2|Bacteria,1NA3X@1224|Proteobacteria,2VWX0@28216|Betaproteobacteria,1KAW7@119060|Burkholderiaceae 28216|Betaproteobacteria KT phage-related functions and prophages - - - - - - - - - - - - HNH_3 k59_38042_1 1692248.A0A0K1RLN2_9CIRC 3.8e-31 119.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_147521_2 1100720.ALKN01000018_gene1741 2.13e-18 82.4 2CEI6@1|root,2ZED5@2|Bacteria,1RCK0@1224|Proteobacteria 1224|Proteobacteria S Protein of unknown function (DUF669) - - - - - - - - - - - - DUF669 k59_188219_1 1788447.A0A190WHJ9_9CIRC 1.58e-73 231.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_13197_2 1548905.A0A0A1IVS1_9CAUD 4.75e-281 777.0 4QH10@10239|Viruses,4QSY9@28883|Caudovirales,4QMA5@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_13197_28 1042375.AFPL01000026_gene3566 6.31e-17 83.6 COG0847@1|root,COG0847@2|Bacteria,1R9YS@1224|Proteobacteria,1S23K@1236|Gammaproteobacteria,46BN2@72275|Alteromonadaceae 1236|Gammaproteobacteria L 3' exoribonuclease, RNase T-like - - - ko:K10906 - - - - ko00000,ko01000,ko03400 - - - DUF5051,Exonuc_VIII k59_13197_31 1548905.A0A0A1IWL1_9CAUD 1.66e-36 134.0 4QAQV@10239|Viruses,4QPCB@28883|Caudovirales 28883|Caudovirales S protein disulfide oxidoreductase activity - - - - - - - - - - - - - k59_13197_34 1548905.A0A0A1IV50_9CAUD 0.0 1138.0 4QAY9@10239|Viruses,4QRJC@28883|Caudovirales,4QKUM@10699|Siphoviridae 10699|Siphoviridae S hydrolase activity, acting on acid anhydrides - - - - - - - - - - - - - k59_13197_36 1548905.A0A0A1IWL0_9CAUD 1.03e-47 157.0 4QBB3@10239|Viruses,4QS3V@28883|Caudovirales,4QMHJ@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_13197_37 1276246.SCULI_v1c07630 6.35e-12 68.2 COG2131@1|root,COG2131@2|Bacteria,3WTJG@544448|Tenericutes 544448|Tenericutes F Deoxycytidylate deaminase comEB - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 k59_13197_38 1548905.A0A0A1IWZ4_9CAUD 2.13e-179 519.0 4QAKM@10239|Viruses,4QPEF@28883|Caudovirales,4QKNE@10699|Siphoviridae 10699|Siphoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_264090_1 1609634.A0A0C5AFV4_9VIRU 7.23e-76 243.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_264090_3 1609634.A0A0C5AFT2_9VIRU 7.7e-24 100.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_123583_1 145579.CAPSD_BPPHM 1.17e-42 161.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_254765_1 1121011.AUCB01000031_gene2179 8.83e-17 94.7 COG1361@1|root,COG2152@1|root,COG3204@1|root,COG1361@2|Bacteria,COG2152@2|Bacteria,COG3204@2|Bacteria 2|Bacteria L pilus organization - - - ko:K02674,ko:K07004 - - - - ko00000,ko02035,ko02044 - - - DUF11,LTD k59_14417_2 1192034.CAP_1091 2.56e-25 117.0 COG0507@1|root,COG0507@2|Bacteria,1R1AT@1224|Proteobacteria,42UU6@68525|delta/epsilon subdivisions,2X85I@28221|Deltaproteobacteria 28221|Deltaproteobacteria L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD - - - - - - - - - - - - - k59_173427_5 1449355.JQNR01000006_gene2143 5.71e-13 77.4 2D784@1|root,32TNH@2|Bacteria,2GRDQ@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_73383_3 1379713.S5SYD9_9CIRC 9.43e-12 69.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_237906_1 1676184.A0A186YBN5_9CIRC 1.54e-29 118.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_164050_1 521096.Tpau_4164 2.38e-32 131.0 COG0305@1|root,COG0305@2|Bacteria,2GKXQ@201174|Actinobacteria 201174|Actinobacteria L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3 k59_206249_2 1986029.Q9MBM6_9VIRU 1.69e-22 94.0 4QDBB@10239|Viruses,4QUM0@29258|ssDNA viruses,4QP4D@10841|Microviridae 10841|Microviridae S Chlamydia-phage Chp2 scaffold (Chlamy_scaf) - - - - - - - - - - - - - k59_97136_2 742740.HMPREF9474_02251 8.16e-18 79.0 2EK5K@1|root,33DW0@2|Bacteria,1UU54@1239|Firmicutes,255II@186801|Clostridia 186801|Clostridia S Putative phage holin Dp-1 - - - - - - - - - - - - Phage_holin_Dp1 k59_246389_1 1165094.RINTHH_3920 1.04e-71 229.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_22801_1 1123250.KB908413_gene334 3.7e-92 298.0 COG5545@1|root,COG5545@2|Bacteria,1TQNX@1239|Firmicutes,4H3CH@909932|Negativicutes 909932|Negativicutes S Virulence-associated protein E - - - - - - - - - - - - VirE k59_206367_1 883080.HMPREF9697_01794 1.14e-06 53.5 COG5434@1|root,COG5434@2|Bacteria,1QW8B@1224|Proteobacteria,2TSD5@28211|Alphaproteobacteria,3JQXR@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Pectate lyase superfamily protein - - - - - - - - - - - - Pectate_lyase_3 k59_190189_1 1029823.AFIE01000007_gene1881 1.11e-105 387.0 COG0454@1|root,COG0553@1|root,COG0827@1|root,COG1040@1|root,COG4646@1|root,COG0456@2|Bacteria,COG0553@2|Bacteria,COG0827@2|Bacteria,COG1040@2|Bacteria,COG4646@2|Bacteria,1MXQH@1224|Proteobacteria,1T52I@1236|Gammaproteobacteria,3NTTI@468|Moraxellaceae 1236|Gammaproteobacteria L methylase - - - - - - - - - - - - - k59_63914_1 1216007.AOPM01000114_gene268 1.74e-08 55.1 COG4128@1|root,COG4128@2|Bacteria,1REHG@1224|Proteobacteria,1S491@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Zonular occludens toxin (Zot) - - - - - - - - - - - - Zot k59_32702_1 1385658.U5KPZ6_9VIRU 2.11e-48 173.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_264265_1 1082931.KKY_703 8.86e-15 83.2 COG4733@1|root,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria,2TV2W@28211|Alphaproteobacteria 28211|Alphaproteobacteria S COG4733 Phage-related protein, tail component - - - - - - - - - - - - Phage-tail_3 k59_57059_1 497964.CfE428DRAFT_3808 9.92e-66 214.0 COG2304@1|root,COG2304@2|Bacteria 2|Bacteria IU oxidoreductase activity mtsE - - - - - - - - - - - TROVE,VWA_2 k59_214934_1 1408424.JHYI01000032_gene3839 1.54e-53 186.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4H9YP@91061|Bacilli,1ZB0Z@1386|Bacillus 91061|Bacilli KL SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,SNF2_N k59_98697_1 1283077.M1INZ1_9CAUD 1.23e-44 169.0 4QCM5@10239|Viruses,4QVZY@35237|dsDNA viruses no RNA stage,4QQFH@28883|Caudovirales,4QNDH@10744|Podoviridae 10744|Podoviridae S Bacteriophage head to tail connecting protein - GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019028,GO:0019058,GO:0019068,GO:0019072,GO:0019073,GO:0032991,GO:0044403,GO:0044419,GO:0044423,GO:0046798,GO:0051704 - - - - - - - - - - - k59_247906_1 497965.Cyan7822_3833 1.25e-17 94.4 COG0210@1|root,COG0210@2|Bacteria,1GQP4@1117|Cyanobacteria 1117|Cyanobacteria L PFAM UvrD REP helicase - - - - - - - - - - - - UvrD-helicase,UvrD_C k59_240162_2 159087.Daro_2692 6.53e-21 97.1 2DSE3@1|root,33FRF@2|Bacteria,1NKQ7@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_265070_2 1618248.A0A0C5IB82_9CIRC 2.94e-13 76.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_256948_1 1527515.A0A088FB58_9CAUD 5.41e-51 194.0 4QAK6@10239|Viruses,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - GO:0008150,GO:0044403,GO:0044409,GO:0044411,GO:0044419,GO:0051701,GO:0051704,GO:0051828,GO:0051830,GO:0085027 - - - - - - - - - - - k59_98989_1 665950.HMPREF1025_02006 1.7e-39 135.0 2ARVA@1|root,31H70@2|Bacteria,1V7JT@1239|Firmicutes,24JPE@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - HK97-gp10_like k59_98989_2 428125.CLOLEP_01422 1.35e-112 367.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia,3WN92@541000|Ruminococcaceae 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_215304_2 1168547.L7P648_9CIRC 4.53e-35 138.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_65906_1 1122132.AQYH01000015_gene2287 3.75e-16 81.3 COG1408@1|root,COG1408@2|Bacteria,1NUS0@1224|Proteobacteria,2UR92@28211|Alphaproteobacteria 28211|Alphaproteobacteria S metallophosphoesterase - - - - - - - - - - - - - k59_65917_1 1123072.AUDH01000059_gene1266 1.28e-28 118.0 COG4643@1|root,COG5545@1|root,COG4643@2|Bacteria,COG5545@2|Bacteria,1MVGK@1224|Proteobacteria,2U0ID@28211|Alphaproteobacteria,2JVCN@204441|Rhodospirillales 204441|Rhodospirillales S Virulence-associated protein E - - - - - - - - - - - - Toprim_3,VirE k59_248275_3 331869.BAL199_07303 2.06e-88 276.0 COG0451@1|root,COG0451@2|Bacteria,1PB4Y@1224|Proteobacteria,2TTV7@28211|Alphaproteobacteria,4BQC1@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria M 3-beta hydroxysteroid dehydrogenase/isomerase family - - - - - - - - - - - - Epimerase k59_265073_1 1411685.U062_00592 4.4e-44 161.0 2EW57@1|root,33PIB@2|Bacteria,1NQQA@1224|Proteobacteria,1SMVX@1236|Gammaproteobacteria,1J7VZ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Phage replication protein CRI - - - - - - - - - - - - Phage_CRI k59_265073_5 626887.J057_00589 3.78e-15 72.0 2EQAG@1|root,33HWM@2|Bacteria,1NM78@1224|Proteobacteria,1SJEQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_265073_6 672.VV93_v1c15400 1.67e-34 123.0 COG1396@1|root,COG1396@2|Bacteria,1NASR@1224|Proteobacteria,1SEP1@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Cro/C1-type HTH DNA-binding domain - - - - - - - - - - - - HTH_19,HTH_3 k59_99008_3 74547.PMT_0110 2.85e-10 65.1 COG0500@1|root,COG0500@2|Bacteria 2|Bacteria Q methyltransferase activity - - - - - - - - - - - - Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31 k59_99008_4 118163.Ple7327_2120 1.36e-17 84.3 COG4627@1|root,COG4627@2|Bacteria,1G34B@1117|Cyanobacteria 1117|Cyanobacteria S PFAM Methyltransferase domain - - - - - - - - - - - - Methyltransf_11 k59_240519_7 1415780.JPOG01000001_gene1751 2.74e-25 111.0 291GM@1|root,2ZP3A@2|Bacteria,1RD1E@1224|Proteobacteria,1S4X6@1236|Gammaproteobacteria,1X9SN@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - k59_116136_2 574087.Acear_0340 9.72e-30 136.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia,3WAIG@53433|Halanaerobiales 186801|Clostridia L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_116136_4 91464.S7335_1407 2.89e-56 199.0 COG0507@1|root,COG0507@2|Bacteria,1G8N5@1117|Cyanobacteria,1GZPG@1129|Synechococcus 1117|Cyanobacteria L COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member - - 3.1.11.5 ko:K01144 - - - - ko00000,ko01000 - - - AAA_30,UvrD_C_2 k59_74669_6 105154.Q9MBU6_9VIRU 1.87e-114 347.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_107854_3 1609634.A0A0C5AFV4_9VIRU 3.72e-15 74.7 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_132737_1 857293.CAAU_0809 8.12e-08 58.9 COG5283@1|root,COG5283@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - PhageMin_Tail k59_232255_1 691965.D4P7L7_9CAUD 1.25e-40 154.0 4QB9J@10239|Viruses,4QXFE@35237|dsDNA viruses no RNA stage,4QS1Z@28883|Caudovirales,4QN8F@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_182465_1 1227349.C170_21765 4.65e-56 192.0 29WPN@1|root,30IAJ@2|Bacteria,1TXQ7@1239|Firmicutes,4I6RD@91061|Bacilli,26UGH@186822|Paenibacillaceae 91061|Bacilli - - - - - - - - - - - - - - - k59_99561_2 497964.CfE428DRAFT_5515 1.52e-07 61.6 COG0265@1|root,COG4733@1|root,COG0265@2|Bacteria,COG4733@2|Bacteria,46Z8W@74201|Verrucomicrobia 74201|Verrucomicrobia O Right handed beta helix region - - - - - - - - - - - - Beta_helix k59_41518_1 1692255.A0A0K1RL13_9CIRC 1.06e-20 92.4 4QCY8@10239|Viruses,4QUMD@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_41518_2 1692252.A0A0K1RL35_9CIRC 4.41e-122 355.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_157604_1 641526.ADIWIN_3626 1.57e-14 79.7 COG1061@1|root,COG1061@2|Bacteria,4NECV@976|Bacteroidetes,1HWX1@117743|Flavobacteriia 976|Bacteroidetes L type III restriction enzyme, res subunit - - - - - - - - - - - - Helicase_C,ResIII k59_257136_1 279280.Q6J1R6_9CAUD 7.03e-16 80.5 4QBMX@10239|Viruses,4QV9I@35237|dsDNA viruses no RNA stage,4QQGF@28883|Caudovirales,4QNC1@10744|Podoviridae 10744|Podoviridae S Pfam:Tube - GO:0005575,GO:0019012 - - - - - - - - - - - k59_257136_2 1238182.C882_1989 8.64e-64 222.0 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,2TVGJ@28211|Alphaproteobacteria,2JPR0@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - k59_141033_2 1151292.QEW_0873 1.06e-13 70.5 COG1475@1|root,COG1475@2|Bacteria,1TR7E@1239|Firmicutes,24AXU@186801|Clostridia 186801|Clostridia K ParB-like nuclease domain - - - - - - - - - - - - ParBc k59_240534_1 935261.JAGL01000009_gene1168 1.32e-30 115.0 COG1351@1|root,COG1351@2|Bacteria,1MWY8@1224|Proteobacteria,2TTER@28211|Alphaproteobacteria,43QDX@69277|Phyllobacteriaceae 28211|Alphaproteobacteria F Thymidylate synthase complementing protein thyX - 2.1.1.148 ko:K03465 ko00240,ko00670,ko01100,map00240,map00670,map01100 - R06613 RC00022,RC00332 ko00000,ko00001,ko01000 - - - Thy1 k59_33232_6 1120980.JQKH01000011_gene1220 4.15e-35 137.0 COG3500@1|root,COG3500@2|Bacteria,1MXT8@1224|Proteobacteria,2VN6E@28216|Betaproteobacteria,2KQVY@206351|Neisseriales 206351|Neisseriales S Phage late control gene D protein (GPD) - - - ko:K06905 - - - - ko00000 - - - Phage_GPD k59_141048_8 1480731.X2KUH8_9CAUD 1.26e-08 67.4 4QAK6@10239|Viruses,4QPBY@28883|Caudovirales 28883|Caudovirales S N-acetylmuramoyl-L-alanine amidase activity - GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0008150,GO:0016032,GO:0016787,GO:0016798,GO:0019012,GO:0019058,GO:0019062,GO:0022610,GO:0044403,GO:0044406,GO:0044409,GO:0044411,GO:0044419,GO:0044423,GO:0044650,GO:0051701,GO:0051704,GO:0051828,GO:0051830,GO:0085027,GO:0098015,GO:0098024 - - - - - - - - - - - k59_232718_1 768066.HELO_2629 6.01e-29 129.0 COG0454@1|root,COG0456@2|Bacteria,1RJ9R@1224|Proteobacteria 1224|Proteobacteria K Muramidase (Phage lambda lysozyme) - - - - - - - - - - - - - k59_141506_1 1217705.F900_01822 1.47e-06 55.5 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,1RR0M@1236|Gammaproteobacteria,3NM85@468|Moraxellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_99998_1 488538.SAR116_0387 6.3e-186 536.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2TS19@28211|Alphaproteobacteria,4BP86@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides - - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_lgC,Ribonuc_red_lgN k59_99998_2 1211640.K4K619_9CAUD 2e-11 65.5 4QHHF@10239|Viruses,4QVRF@35237|dsDNA viruses no RNA stage,4QRG3@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_191183_1 948071.S4S2D9_9CAUD 8.51e-78 250.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QNQ6@10744|Podoviridae 10744|Podoviridae S ribonucleoside-triphosphate reductase activity - - - - - - - - - - - - - k59_8842_1 105154.Q9MBU6_9VIRU 3.98e-38 149.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_8842_5 1234888.K0A2J2_9VIRU 1.52e-44 160.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_149775_1 1120977.JHUX01000003_gene847 1.48e-13 73.6 2E5GW@1|root,3308F@2|Bacteria,1N8DS@1224|Proteobacteria,1STKW@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknwon function (DUF3310) - - - - - - - - - - - - DUF3310 k59_199543_1 1564096.A0A0A0YS96_9CAUD 2.53e-10 67.4 4QBB8@10239|Viruses,4QQZ7@28883|Caudovirales,4QKKE@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_249284_3 1120977.JHUX01000003_gene1143 3.23e-18 96.7 COG0507@1|root,COG1372@1|root,COG0507@2|Bacteria,COG1372@2|Bacteria,1R1AT@1224|Proteobacteria,1RZWT@1236|Gammaproteobacteria,3NKPB@468|Moraxellaceae 1236|Gammaproteobacteria L Participates in initiation and elongation during chromosome replication - - - - - - - - - - - - Hom_end_hint k59_249284_4 936136.ARRT01000006_gene4475 4.08e-23 110.0 COG4383@1|root,COG4383@2|Bacteria,1MWNS@1224|Proteobacteria,2TR0Y@28211|Alphaproteobacteria,4BDT6@82115|Rhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF935) - - - - - - - - - - - - DUF935 k59_75194_2 1618248.A0A0C5IB82_9CIRC 6.8e-85 263.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_91748_1 1245471.PCA10_29240 8.73e-74 241.0 COG4128@1|root,COG4128@2|Bacteria,1RK87@1224|Proteobacteria,1SYAX@1236|Gammaproteobacteria,1YH69@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Zonular occludens toxin (Zot) - - - ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko02042 - - - Zot k59_91748_2 1219076.N646_0606 2.13e-20 85.9 2CHQ6@1|root,33N6R@2|Bacteria,1NM75@1224|Proteobacteria,1SUNZ@1236|Gammaproteobacteria,1Y1UP@135623|Vibrionales 1236|Gammaproteobacteria S Protein of unknown function (DUF2523) - - - - - - - - - - - - DUF2523 k59_91748_8 1177181.T9A_00229 6.12e-39 149.0 COG2946@1|root,COG2946@2|Bacteria,1RDKM@1224|Proteobacteria,1S7EJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Replication initiation factor - - - - - - - - - - - - Rep_trans k59_75195_1 272568.GDI3670 4.18e-28 121.0 COG0234@1|root,COG0234@2|Bacteria,1NJKP@1224|Proteobacteria,2UM25@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter - - - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - - k59_249286_1 1129194.I3PGX6_9CAUD 2.72e-07 53.5 4QCMK@10239|Viruses,4QUPQ@35237|dsDNA viruses no RNA stage,4QS1R@28883|Caudovirales,4QKCR@10662|Myoviridae 10662|Myoviridae S methyltransferase activity - - - - - - - - - - - - - k59_207804_1 1215092.PA6_009_00130 7.94e-13 82.8 COG0454@1|root,COG0503@1|root,COG1040@1|root,COG0456@2|Bacteria,COG0503@2|Bacteria,COG1040@2|Bacteria,1QV41@1224|Proteobacteria,1SZB6@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis - - - - - - - - - - - - - k59_141635_1 105154.Q9MBU3_9VIRU 1.2e-11 67.0 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_108379_1 1692250.A0A0K1RLR1_9CIRC 1.36e-28 114.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_8928_2 118163.Ple7327_0190 2.93e-07 57.8 COG2202@1|root,COG3829@1|root,COG4251@1|root,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria,1G0A1@1117|Cyanobacteria,3VHNF@52604|Pleurocapsales 1117|Cyanobacteria T PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9 k59_191216_1 1609634.A0A0C5AFV4_9VIRU 1.72e-90 288.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_191216_2 105154.Q9MBU3_9VIRU 4.75e-08 58.9 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_1323_1 411459.RUMOBE_01947 0.000112 46.2 arCOG12654@1|root,330YI@2|Bacteria,1VGQU@1239|Firmicutes,24N61@186801|Clostridia,3Y1QA@572511|Blautia 186801|Clostridia S HIRAN domain - - - - - - - - - - - - HIRAN k59_26150_1 1120970.AUBZ01000070_gene1594 1.38e-76 244.0 2CEG2@1|root,2ZCEX@2|Bacteria,1RB74@1224|Proteobacteria,1S2JC@1236|Gammaproteobacteria,46AFF@72275|Alteromonadaceae 1236|Gammaproteobacteria S Phage replication protein CRI - - - - - - - - - - - - Phage_CRI,Phage_X k59_26150_7 582744.Msip34_2836 8.64e-59 201.0 COG0464@1|root,COG0464@2|Bacteria,1QU82@1224|Proteobacteria,2WHSD@28216|Betaproteobacteria,2KNN6@206350|Nitrosomonadales 206350|Nitrosomonadales O Zonular occludens toxin (Zot) - - - - - - - - - - - - Zot k59_26150_10 1215092.PA6_046_00270 1.98e-10 57.4 28QDM@1|root,2ZCVZ@2|Bacteria,1P5MR@1224|Proteobacteria,1SW6Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_17417_1 592316.Pat9b_2114 1.94e-05 53.1 COG1511@1|root,COG1511@2|Bacteria,1QWV3@1224|Proteobacteria,1T4UM@1236|Gammaproteobacteria 1236|Gammaproteobacteria S tail tape measure protein - - - - - - - - - - - - - k59_67464_3 1385658.U5KPZ6_9VIRU 1.24e-183 530.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_92400_5 1204524.K4HY20_9CAUD 1.88e-11 63.5 4QHN2@10239|Viruses,4QVFE@35237|dsDNA viruses no RNA stage,4QTI8@28883|Caudovirales,4QMAV@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_75865_1 1219035.NT2_13_00580 1.24e-33 133.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_83958_3 105154.Q9MBU6_9VIRU 1.03e-180 527.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_200088_2 626418.bglu_1g15460 7.08e-61 192.0 2C5J1@1|root,3067M@2|Bacteria,1N4SF@1224|Proteobacteria,2VWDM@28216|Betaproteobacteria,1K9HT@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_17438_1 471870.BACINT_04412 3.17e-23 104.0 COG3866@1|root,COG3866@2|Bacteria,4P09P@976|Bacteroidetes,2FNQB@200643|Bacteroidia,4AMAR@815|Bacteroidaceae 976|Bacteroidetes G pectate lyase K01728 - - - - - - - - - - - - - k59_249860_1 1235811.HMPREF0653_01905 5.56e-27 118.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,2FM8X@200643|Bacteroidia 976|Bacteroidetes L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_50928_1 1229485.AMYV01000122_gene2641 3.07e-17 80.1 COG0582@1|root,COG0582@2|Bacteria,1N45B@1224|Proteobacteria,1RNDM@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Belongs to the 'phage' integrase family int - - - - - - - - - - - Phage_integrase k59_1385_1 1042377.AFPJ01000024_gene772 3.59e-22 100.0 COG0463@1|root,COG0463@2|Bacteria,1MX1N@1224|Proteobacteria,1S06M@1236|Gammaproteobacteria,464R2@72275|Alteromonadaceae 1236|Gammaproteobacteria M Glycosyl transferase, family 2 - - - - - - - - - - - - Glycos_transf_2 k59_1385_6 1566993.A0A0A7HER9_9CAUD 4.53e-50 184.0 4QEW8@10239|Viruses,4QTWI@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_225110_1 945713.IALB_0073 3.09e-36 148.0 COG3941@1|root,COG3941@2|Bacteria 2|Bacteria O tape measure - - - - - - - - - - - - - k59_230863_1 1444309.JAQG01000084_gene3059 1.44e-21 104.0 COG0714@1|root,COG0714@2|Bacteria,1UXAG@1239|Firmicutes,4HC1E@91061|Bacilli,26VTC@186822|Paenibacillaceae 91061|Bacilli S AAA domain (dynein-related subfamily) - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_5 k59_63871_1 1096546.WYO_0193 1.28e-25 103.0 28JC4@1|root,2Z96S@2|Bacteria,1RI8W@1224|Proteobacteria 1224|Proteobacteria S P22 coat protein-protein 5 domain protein - - - - - - - - - - - - - k59_196894_1 243365.CV_3049 2.36e-17 80.9 COG4696@1|root,COG4696@2|Bacteria,1MZY6@1224|Proteobacteria,2VUT3@28216|Betaproteobacteria,2KRTZ@206351|Neisseriales 206351|Neisseriales S Phosphoribosyl-ATP pyrophosphohydrolase - - - - - - - - - - - - PRA-PH k59_97230_1 1618257.A0A0C5IBI9_9CIRC 7.4e-60 196.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_8142_2 313596.RB2501_01306 1.73e-15 85.5 2DNIX@1|root,32XR6@2|Bacteria,4NU21@976|Bacteroidetes,1I3XV@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_213247_2 1453500.AT05_01505 7.25e-46 165.0 COG4974@1|root,COG4974@2|Bacteria,4NGE1@976|Bacteroidetes,1HY1D@117743|Flavobacteriia 976|Bacteroidetes L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_int_SAM_4,Phage_integrase k59_246564_1 105154.Q9MBU6_9VIRU 8.41e-29 114.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_254973_3 1121035.AUCH01000018_gene2791 1.51e-56 188.0 COG3409@1|root,COG3409@2|Bacteria,1RAFU@1224|Proteobacteria 1224|Proteobacteria M Peptidoglycan-binding domain 1 protein - - - - - - - - - - - - PG_binding_1,Peptidase_M15_4 k59_254973_4 292414.TM1040_1304 1.03e-11 65.1 2ET4N@1|root,33KNS@2|Bacteria,1NH2P@1224|Proteobacteria,2UNDH@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_254973_5 1051675.G0YQI0_9CAUD 4.73e-296 833.0 4QF3C@10239|Viruses,4QWIA@35237|dsDNA viruses no RNA stage,4QU4U@28883|Caudovirales,4QNNQ@10744|Podoviridae 10744|Podoviridae S host cell wall - - - - - - - - - - - - - k59_254973_7 1458848.X2KY27_9CAUD 3.66e-60 208.0 4QEQT@10239|Viruses,4QYJH@35237|dsDNA viruses no RNA stage,4QQ1B@28883|Caudovirales,4QNPW@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_254973_8 1051675.G0YQH7_9CAUD 1.32e-209 588.0 4QGGR@10239|Viruses,4QZHR@35237|dsDNA viruses no RNA stage,4QUGZ@28883|Caudovirales,4QNY3@10744|Podoviridae 10744|Podoviridae S viral capsid - - - - - - - - - - - - - k59_254973_9 10752.Q859Q4_BPN4 7.55e-44 152.0 4QDXM@10239|Viruses,4QWIX@35237|dsDNA viruses no RNA stage,4QQF6@28883|Caudovirales,4QNXH@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_254973_10 1395983.A0A067Y1A9_9CAUD 1.05e-46 164.0 4QBYE@10239|Viruses,4QVYH@35237|dsDNA viruses no RNA stage,4QQTP@28883|Caudovirales,4QP46@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_156742_1 665956.HMPREF1032_00686 1.22e-46 173.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia,3WN92@541000|Ruminococcaceae 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_264328_3 1088721.NSU_0757 9.54e-41 135.0 2AJ1X@1|root,319K5@2|Bacteria,1RK0X@1224|Proteobacteria,2UKUD@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF2829) - - - - - - - - - - - - DUF2829 k59_131934_2 411684.HPDFL43_04261 8.86e-22 94.7 COG0741@1|root,COG0741@2|Bacteria,1RH42@1224|Proteobacteria,2UST0@28211|Alphaproteobacteria 28211|Alphaproteobacteria M lytic transglycosylase activity - - - - - - - - - - - - SLT k59_115723_1 243231.GSU2376 3.58e-21 90.5 2DA0E@1|root,32TUD@2|Bacteria,1QXP4@1224|Proteobacteria,430AH@68525|delta/epsilon subdivisions,2WVN8@28221|Deltaproteobacteria,43VAX@69541|Desulfuromonadales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_32795_1 1609634.A0A0C5AFT2_9VIRU 1.61e-77 243.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_156746_1 2003327.CAPSD_BPCHP 3.44e-46 166.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_73614_1 1443113.LC20_01749 2.01e-22 97.4 COG0616@1|root,COG0616@2|Bacteria,1QGPW@1224|Proteobacteria,1RZZW@1236|Gammaproteobacteria,41H6V@629|Yersinia 1236|Gammaproteobacteria OU Peptidase family S49 JD73_18850 - - ko:K21511 - - - - ko00000,ko01000 - - - Peptidase_S49 k59_73614_2 255431.Q6UAX8_9CAUD 1.12e-89 282.0 4QAYV@10239|Viruses,4QUZ7@35237|dsDNA viruses no RNA stage,4QPU3@28883|Caudovirales,4QKKX@10699|Siphoviridae 10699|Siphoviridae S Phage portal protein - - - - - - - - - - - - - k59_213383_1 1385658.U5KPZ6_9VIRU 9.92e-78 250.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_123874_1 156889.Mmc1_2604 7.81e-51 171.0 COG1475@1|root,COG4725@1|root,COG1475@2|Bacteria,COG4725@2|Bacteria,1R553@1224|Proteobacteria,2TRP6@28211|Alphaproteobacteria 28211|Alphaproteobacteria KT Belongs to the MT-A70-like family - - - - - - - - - - - - MT-A70 k59_123874_2 34007.IT40_02330 1.83e-27 108.0 28PMA@1|root,2ZCAD@2|Bacteria,1RARQ@1224|Proteobacteria,2U6X3@28211|Alphaproteobacteria,2PUUP@265|Paracoccus 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_230976_1 716928.AJQT01000109_gene1217 9.08e-20 84.7 2FEUE@1|root,346TC@2|Bacteria,1MZPB@1224|Proteobacteria,2UC4Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_64975_1 756275.H2BCT8_9CAUD 1.52e-13 75.9 4QMPJ@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_106964_2 1692257.A0A0K1RL39_9CIRC 1.76e-37 139.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_82401_2 637390.AFOH01000038_gene2455 2.01e-15 79.7 COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,1RPA0@1236|Gammaproteobacteria,2NBWR@225057|Acidithiobacillales 225057|Acidithiobacillales L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity recD2 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 k59_74525_1 105154.Q9MBU3_9VIRU 5.07e-14 70.1 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_89054_1 1122139.KB907868_gene1223 1.43e-05 54.3 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1XI69@135619|Oceanospirillales 135619|Oceanospirillales L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_165329_1 1560342.A0A0A0RMR6_9CAUD 1.47e-28 120.0 4QAKM@10239|Viruses,4QPEF@28883|Caudovirales,4QI32@10662|Myoviridae 10662|Myoviridae S DNA polymerase family A - - - - - - - - - - - - - k59_98219_1 1082932.ATCR1_06801 5e-24 100.0 2C22H@1|root,305QB@2|Bacteria,1RFAD@1224|Proteobacteria,2U8GY@28211|Alphaproteobacteria,4BEFE@82115|Rhizobiaceae 28211|Alphaproteobacteria S Chaperone of endosialidase - - - - - - - - - - - - Peptidase_S74 k59_231937_1 387344.LVIS_0044 5.38e-09 59.3 COG0338@1|root,COG0338@2|Bacteria,1TRDX@1239|Firmicutes,4HDFS@91061|Bacilli,3F3TA@33958|Lactobacillaceae 91061|Bacilli H Site-specific DNA-methyltransferase (adenine-specific) dpnM - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 k59_231937_2 1235803.C825_01399 6.19e-10 62.0 COG2852@1|root,COG2852@2|Bacteria,4NX7B@976|Bacteroidetes,2FV38@200643|Bacteroidia 976|Bacteroidetes S Protein conserved in bacteria - - - - - - - - - - - - - k59_15714_1 2003327.CAPSD_BPCHP 1.31e-09 65.1 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_24099_1 439235.Dalk_2109 1.59e-30 131.0 COG0358@1|root,COG0470@1|root,COG0358@2|Bacteria,COG0470@2|Bacteria,1PFYB@1224|Proteobacteria,431A2@68525|delta/epsilon subdivisions,2WWTZ@28221|Deltaproteobacteria 28221|Deltaproteobacteria L Toprim-like - - - - - - - - - - - - Toprim_2 k59_82511_1 65489.OBART02G25380.1 5.01e-05 48.9 COG0320@1|root,KOG2220@1|root,KOG2220@2759|Eukaryota,KOG2672@2759|Eukaryota,389FG@33090|Viridiplantae,3GYJC@35493|Streptophyta,3MB4W@4447|Liliopsida,3IUPZ@38820|Poales 35493|Streptophyta K BRO1-like domain - - - ko:K12200 ko04144,map04144 - - - ko00000,ko00001,ko04131,ko04147 - - - AP2,BRO1,FeThRed_A k59_198333_1 1234888.K0A2J2_9VIRU 3.6e-51 182.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_82519_1 634504.Bgr_15850 7.13e-11 69.3 COG4643@1|root,COG4643@2|Bacteria,1N08G@1224|Proteobacteria,2U9N8@28211|Alphaproteobacteria,48SYH@772|Bartonellaceae 28211|Alphaproteobacteria S membrane spanning protein Brucella melitensis 16M gi 17987979 ref - - - - - - - - - - - - DUF3987 k59_107043_1 1122201.AUAZ01000017_gene2947 8.01e-153 468.0 COG0749@1|root,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,465DD@72275|Alteromonadaceae 1236|Gammaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity - - - - - - - - - - - - DNA_pol_A k59_107043_2 1540097.A0A0A0YPX0_9CAUD 6.49e-74 238.0 4QEG2@10239|Viruses,4QRJ9@28883|Caudovirales,4QP0R@10744|Podoviridae 10744|Podoviridae S exonuclease activity - - - - - - - - - - - - - k59_107043_3 1476391.X5KCC8_9CAUD 4.56e-147 444.0 4QGA5@10239|Viruses,4QURD@35237|dsDNA viruses no RNA stage,4QT9N@28883|Caudovirales,4QP47@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_24260_1 207559.Dde_3372 8.32e-73 243.0 COG4373@1|root,COG4373@2|Bacteria,1N2KG@1224|Proteobacteria,42NZD@68525|delta/epsilon subdivisions,2WJWU@28221|Deltaproteobacteria,2M8CI@213115|Desulfovibrionales 28221|Deltaproteobacteria S Mu-like prophage FluMu protein gp28 - - - - - - - - - - - - Terminase_6 k59_199065_2 1636271.A0A0E3M3Z6_9CAUD 1.06e-57 191.0 4QFVK@10239|Viruses,4QSUR@28883|Caudovirales,4QM8N@10699|Siphoviridae 10699|Siphoviridae S transferase activity - - - - - - - - - - - - - k59_82983_1 1298858.AUEL01000009_gene4355 8.81e-23 90.1 29WMW@1|root,30I8Q@2|Bacteria,1NNZN@1224|Proteobacteria 1224|Proteobacteria S Protein of unknwon function (DUF3310) - - - - - - - - - - - - DUF3310 k59_248836_2 1161401.ASJA01000028_gene62 8.71e-16 76.6 2FBVH@1|root,34403@2|Bacteria,1MZQN@1224|Proteobacteria,2UC63@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_157660_1 1144310.PMI07_002369 1.52e-23 108.0 28QU5@1|root,2ZD9H@2|Bacteria,1RAU8@1224|Proteobacteria,2U2GD@28211|Alphaproteobacteria,4BC6R@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_157660_2 358220.C380_10860 3.87e-17 80.1 COG1670@1|root,COG1670@2|Bacteria,1ND46@1224|Proteobacteria,2W4JU@28216|Betaproteobacteria 28216|Betaproteobacteria J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - - - - - - - - - - - k59_157660_3 716928.AJQT01000006_gene2763 0.000159 51.2 2C22H@1|root,305QB@2|Bacteria,1RFAD@1224|Proteobacteria,2U8GY@28211|Alphaproteobacteria,4BEFE@82115|Rhizobiaceae 28211|Alphaproteobacteria S Chaperone of endosialidase - - - - - - - - - - - - Peptidase_S74 k59_107957_2 654929.REP_PCV1C 1.08e-25 112.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_99613_1 760192.Halhy_0673 7.23e-10 59.3 COG4122@1|root,COG4122@2|Bacteria 2|Bacteria E O-methyltransferase activity - - - - - - - - - - - - Glycos_transf_2,Methyltransf_24 k59_257220_1 478749.BRYFOR_08513 9.79e-55 193.0 COG3409@1|root,COG3409@2|Bacteria 2|Bacteria M Peptidoglycan-binding domain 1 protein - - - - - - - - - - - - Amidase_2,LysM,PG_binding_1 k59_257220_2 428125.CLOLEP_01421 8.33e-21 85.9 2ARVA@1|root,31H70@2|Bacteria,1V7JT@1239|Firmicutes,24JPE@186801|Clostridia,3WP7W@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - HK97-gp10_like k59_157663_1 172088.AUGA01000015_gene2780 2.29e-19 81.6 2D1MV@1|root,32TAZ@2|Bacteria,1N45A@1224|Proteobacteria,2UEJT@28211|Alphaproteobacteria,3K577@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Phage protein (N4 Gp49/phage Sf6 gene 66) family - - - - - - - - - - - - Phage_gp49_66 k59_182557_1 742740.HMPREF9474_02271 4.68e-118 352.0 28J3N@1|root,2Z8ZU@2|Bacteria,1V15Z@1239|Firmicutes,249Z0@186801|Clostridia,221RR@1506553|Lachnoclostridium 186801|Clostridia S Phage portal protein - - - - - - - - - - - - Phage_portal k59_199137_3 1348657.M622_06935 5.96e-17 90.9 COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,2VHG5@28216|Betaproteobacteria,2KUVR@206389|Rhodocyclales 206389|Rhodocyclales L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_3,Phage_integrase k59_215737_3 1219035.NT2_13_00580 3.53e-71 237.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_215737_4 1219035.NT2_13_00600 9.27e-38 140.0 290X3@1|root,2ZNIW@2|Bacteria,1P7TA@1224|Proteobacteria,2UXFQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_141081_1 411460.RUMTOR_02036 0.0 1017.0 2EWZQ@1|root,33QB0@2|Bacteria,1V0T1@1239|Firmicutes,249Z2@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_25040_4 292415.Tbd_2069 3.86e-18 88.6 COG3355@1|root,COG3355@2|Bacteria,1N3ME@1224|Proteobacteria,2VTXQ@28216|Betaproteobacteria 28216|Betaproteobacteria K ROK family - - - - - - - - - - - - - k59_190853_3 105154.Q9MBU6_9VIRU 2.8e-224 637.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_190853_5 1385658.U5KNR1_9VIRU 4.55e-84 263.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_149326_1 1234888.K0A2J2_9VIRU 2.62e-129 388.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_149326_5 145579.REP_BPPHM 1.75e-15 82.8 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_149326_7 1234888.K0A2J2_9VIRU 5.6e-22 95.5 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_34000_1 935261.JAGL01000009_gene1149 6.28e-21 94.4 COG3179@1|root,COG3179@2|Bacteria,1R71F@1224|Proteobacteria,2UD1N@28211|Alphaproteobacteria,43MAV@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S chitinase - - - - - - - - - - - - Glyco_hydro_19 k59_25732_2 1788439.A0A190WHD0_9CIRC 1.36e-21 101.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_100211_2 1498011.A0A096XUT1_9CAUD 4.78e-28 107.0 4QC50@10239|Viruses,4QS0Z@28883|Caudovirales,4QNPK@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_50476_1 1692249.A0A0K1RLN8_9CIRC 9.21e-30 115.0 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_216427_4 997884.HMPREF1068_03186 1.35e-34 132.0 COG1783@1|root,COG1783@2|Bacteria,4NHPB@976|Bacteroidetes,2FR95@200643|Bacteroidia,4AP7A@815|Bacteroidaceae 976|Bacteroidetes S Phage terminase, large subunit, PBSX family - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C k59_34001_1 1357275.AVEL02000138_gene57 2.38e-17 89.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,1RPEK@1236|Gammaproteobacteria,1Z9VV@136849|Pseudomonas syringae group 1236|Gammaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_91991_1 1385658.U5KPZ6_9VIRU 7.05e-50 176.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_125238_2 460265.Mnod_6287 4.73e-19 91.3 2EEQT@1|root,338IH@2|Bacteria,1NCP8@1224|Proteobacteria,2UHWI@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_125238_4 521000.PROVRETT_05969 2.37e-08 55.8 2DIG9@1|root,3036R@2|Bacteria,1RBPA@1224|Proteobacteria,1S2FC@1236|Gammaproteobacteria 1236|Gammaproteobacteria L YqaJ-like viral recombinase domain - - - - - - - - - - - - YqaJ k59_166601_1 264198.Reut_A2380 2.43e-05 50.1 COG2932@1|root,COG2932@2|Bacteria,1Q94I@1224|Proteobacteria,2VW1H@28216|Betaproteobacteria,1K8HH@119060|Burkholderiaceae 28216|Betaproteobacteria K Peptidase S24-like - - - - - - - - - - - - Peptidase_S24 k59_125240_2 671065.MetMK1DRAFT_00033100 2.94e-06 48.5 COG0451@1|root,arCOG01369@2157|Archaea,2XQCJ@28889|Crenarchaeota 28889|Crenarchaeota M PFAM NAD-dependent epimerase dehydratase - - 4.1.1.35,5.1.3.2 ko:K01784,ko:K08678 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R01384,R02984 RC00289,RC00508 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd k59_183180_4 1609634.A0A0C5AFT2_9VIRU 7.96e-127 373.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_183180_6 1609634.A0A0C5AFV4_9VIRU 2.32e-206 589.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_199703_4 1150626.PHAMO_80087 1.87e-16 93.6 COG3941@1|root,COG3941@2|Bacteria,1PHQP@1224|Proteobacteria,2V9RW@28211|Alphaproteobacteria,2JWSI@204441|Rhodospirillales 204441|Rhodospirillales S Lambda phage tail tape-measure protein (Tape_meas_lam_C) - - - - - - - - - - - - Tape_meas_lam_C k59_199703_7 487316.BBNM01000022_gene5 3.9e-31 115.0 COG0791@1|root,COG0791@2|Bacteria,1QP6S@1224|Proteobacteria,1SIU8@1236|Gammaproteobacteria,3NN30@468|Moraxellaceae 1236|Gammaproteobacteria M NlpC/P60 family - - - - - - - - - - - - NLPC_P60 k59_116864_22 1094563.MCQ_00939 1.38e-53 182.0 COG3723@1|root,COG3723@2|Bacteria,1MYMG@1224|Proteobacteria,2U9X7@28211|Alphaproteobacteria,48T6Y@772|Bartonellaceae 28211|Alphaproteobacteria L RecT family bet1 - - - - - - - - - - - RecT k59_50537_3 1498011.A0A096XUY1_9CAUD 9.65e-53 176.0 4QHBE@10239|Viruses,4QT2W@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_17195_1 398578.Daci_1943 5.52e-107 347.0 COG3064@1|root,COG3064@2|Bacteria,1R6JV@1224|Proteobacteria 1224|Proteobacteria M Membrane - - - - - - - - - - - - - k59_257926_1 1337093.MBE-LCI_1903 6.04e-37 135.0 COG1192@1|root,COG1192@2|Bacteria,1RG3F@1224|Proteobacteria,2TVSV@28211|Alphaproteobacteria 28211|Alphaproteobacteria D VirC1 protein - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31,VirC1 k59_174623_1 1121438.JNJA01000011_gene1886 3.2e-19 94.7 COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,42PFW@68525|delta/epsilon subdivisions,2WJ1N@28221|Deltaproteobacteria 1224|Proteobacteria C SMART Elongator protein 3 MiaB NifB - - - - - - - - - - - - B12-binding,Radical_SAM k59_34044_3 690850.Desaf_1351 3.8e-13 77.0 COG0451@1|root,COG0451@2|Bacteria,1QUEV@1224|Proteobacteria,43AGM@68525|delta/epsilon subdivisions,2X5WG@28221|Deltaproteobacteria,2MGWN@213115|Desulfovibrionales 28221|Deltaproteobacteria M PFAM NAD-dependent epimerase dehydratase - - 5.1.3.10,5.1.3.2 ko:K01784,ko:K12454 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984,R04266 RC00289,RC00528 ko00000,ko00001,ko00002,ko01000 - - - Epimerase k59_175219_1 1232428.CAVO010000021_gene805 5.06e-13 73.6 2DBD6@1|root,2Z8I5@2|Bacteria,1UZHS@1239|Firmicutes,4H2J8@909932|Negativicutes 909932|Negativicutes - - - - - - - - - - - - - - Ntox50 k59_233335_2 1618260.A0A0C5I2C5_9CIRC 2.62e-17 80.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_175223_1 648757.Rvan_1474 5.39e-20 94.0 COG1061@1|root,COG1061@2|Bacteria,1MV9F@1224|Proteobacteria,2V8QM@28211|Alphaproteobacteria,3N8M3@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria L helicase superfamily c-terminal domain - - - - - - - - - - - - Helicase_C,ResIII k59_125895_1 323261.Noc_3023 5.26e-42 144.0 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria,1WY0C@135613|Chromatiales 135613|Chromatiales L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism - - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_67669_2 1122917.KB899685_gene3237 1.34e-94 290.0 COG4422@1|root,COG4422@2|Bacteria,1TPP1@1239|Firmicutes,4HAU8@91061|Bacilli,26V16@186822|Paenibacillaceae 91061|Bacilli S Protein of unknown function (DUF5131) - - - - - - - - - - - - DUF5131 k59_67669_3 644107.SL1157_1635 7.18e-51 174.0 COG2404@1|root,COG2404@2|Bacteria,1PKY9@1224|Proteobacteria,2V2FR@28211|Alphaproteobacteria,4NDK2@97050|Ruegeria 28211|Alphaproteobacteria S hydrolase activity, acting on ester bonds - - - - - - - - - - - - - k59_158648_3 655097.C8ZKD0_9CAUD 3.94e-11 65.1 4QAR1@10239|Viruses,4QUNA@35237|dsDNA viruses no RNA stage,4QPJE@28883|Caudovirales,4QNDS@10744|Podoviridae 10744|Podoviridae S ATPase activity - - - - - - - - - - - - - k59_67794_1 1123367.C666_12660 7.04e-50 166.0 2EKAP@1|root,33E0Y@2|Bacteria,1NAAI@1224|Proteobacteria,2VZTN@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_100931_2 1416009.V9VCY6_9CAUD 1.6e-149 436.0 4QGGR@10239|Viruses,4QZHR@35237|dsDNA viruses no RNA stage,4QUGZ@28883|Caudovirales,4QNY3@10744|Podoviridae 10744|Podoviridae S viral capsid - - - - - - - - - - - - - k59_191864_1 445974.CLORAM_02947 3.31e-17 79.7 2E3AH@1|root,32YA0@2|Bacteria,1VGN7@1239|Firmicutes 1239|Firmicutes S Protein of unknown function (DUF1064) - - - - - - - - - - - - DUF1064 k59_126011_1 1196324.A374_01224 1.16e-05 52.8 COG0476@1|root,COG0476@2|Bacteria,1V9AZ@1239|Firmicutes,4HIYB@91061|Bacilli 91061|Bacilli H ThiF family - - - - - - - - - - - - ThiF k59_100935_1 105154.Q9MBU3_9VIRU 5.76e-09 60.1 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_100935_2 1986029.Q9MBM8_9VIRU 8.01e-36 134.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_42967_1 1165094.RINTHH_3920 2.02e-15 75.9 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_42967_4 105154.Q9MBU3_9VIRU 3.37e-06 53.9 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_42967_5 1385658.U5KPZ6_9VIRU 1.17e-110 338.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_175292_1 1234888.K0A2J2_9VIRU 9.97e-43 155.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_217347_1 195253.Syn6312_3793 1.52e-55 197.0 COG1061@1|root,COG1061@2|Bacteria,1G2HP@1117|Cyanobacteria,1H08U@1129|Synechococcus 1117|Cyanobacteria L Helicase conserved C-terminal domain - - - - - - - - - - - - DUF3427,Helicase_C,ResIII k59_9497_1 375286.mma_2769 4.54e-31 132.0 COG0616@1|root,COG0616@2|Bacteria,1QGPW@1224|Proteobacteria,2VJ0N@28216|Betaproteobacteria 28216|Betaproteobacteria OU PFAM peptidase S49 - - - - - - - - - - - - Peptidase_S49 k59_100936_1 268748.Q58N34_BPPRP 5.52e-18 89.0 4QBAU@10239|Viruses,4QW8E@35237|dsDNA viruses no RNA stage,4QPEP@28883|Caudovirales,4QNY1@10744|Podoviridae 10744|Podoviridae S viral capsid assembly - - - - - - - - - - - - - k59_225440_1 399795.CtesDRAFT_PD2908 3.68e-09 60.1 COG5449@1|root,COG5449@2|Bacteria,1MXK2@1224|Proteobacteria,2VSPS@28216|Betaproteobacteria,4AII8@80864|Comamonadaceae 28216|Betaproteobacteria S Phage conserved hypothetical protein BR0599 - - - - - - - - - - - - DUF2163,Phage_BR0599 k59_143167_1 1609634.A0A0C5ANA6_9VIRU 4.58e-07 56.6 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_143167_2 1609634.A0A0C5AFV4_9VIRU 1.78e-196 565.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_159135_2 1096930.L284_17065 7.02e-23 101.0 COG0749@1|root,COG0749@2|Bacteria,1P27P@1224|Proteobacteria,2TVEI@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DNA polymerase family A - - - - - - - - - - - - DNA_pol_A k59_93085_1 1692242.A0A0K1RL37_9CIRC 6.85e-63 203.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_167924_1 313596.RB2501_01435 3.62e-38 134.0 2EHDS@1|root,33B5M@2|Bacteria,4NXR6@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - k59_200860_1 1173762.S4TP25_9CAUD 9.17e-53 187.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_175778_6 1234888.K0A2J2_9VIRU 1.26e-38 148.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_184206_1 1123234.AUKI01000017_gene2483 3.72e-19 91.3 COG0582@1|root,COG0582@2|Bacteria,4NDZJ@976|Bacteroidetes,1HZ88@117743|Flavobacteriia 976|Bacteroidetes L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_5,Phage_int_SAM_5,Phage_integrase k59_208947_1 1109445.AGSX01000152_gene3648 1.04e-06 55.8 COG0582@1|root,COG0582@2|Bacteria,1MVZB@1224|Proteobacteria,1RP4Y@1236|Gammaproteobacteria,1Z2A7@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria L Belongs to the 'phage' integrase family - - - ko:K14059 - - - - ko00000 - - - Arm-DNA-bind_2,Phage_int_SAM_3,Phage_integrase k59_109688_1 1449976.KALB_4993 2.81e-16 78.2 COG1216@1|root,COG1216@2|Bacteria,2I623@201174|Actinobacteria 201174|Actinobacteria S Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 k59_218148_1 883156.HMPREF9282_01239 1.38e-09 59.7 COG3087@1|root,COG3087@2|Bacteria,1TP8N@1239|Firmicutes,4H403@909932|Negativicutes 909932|Negativicutes D Caudovirus prohead protease - - - - - - - - - - - - Peptidase_S78 k59_59825_1 1673638.A0A0H4AJL5_9CIRC 1.23e-39 144.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_192929_1 411461.DORFOR_01175 1.55e-30 127.0 COG5280@1|root,COG5283@1|root,COG5280@2|Bacteria,COG5283@2|Bacteria,1UHQM@1239|Firmicutes,25E9Q@186801|Clostridia 186801|Clostridia M phage tail tape measure protein - - - - - - - - - - - - LysM,Peptidase_M23,PhageMin_Tail k59_102212_1 1158762.KB898038_gene1905 9.29e-23 104.0 COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,1R97W@1224|Proteobacteria 1224|Proteobacteria D Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_102213_1 483216.BACEGG_00594 2.69e-05 52.4 COG0553@1|root,COG0553@2|Bacteria,4NZK9@976|Bacteroidetes,2FRRF@200643|Bacteroidia,4APRR@815|Bacteroidaceae 976|Bacteroidetes KL CRISPR-associated helicase, Cas3 - - - - - - - - - - - - - k59_127506_1 1234888.K0A2J2_9VIRU 7e-36 137.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_201725_1 3218.PP1S77_291V6.1 3.72e-15 76.6 COG0216@1|root,KOG2726@2759|Eukaryota,37SSY@33090|Viridiplantae,3G9BB@35493|Streptophyta 35493|Streptophyta J peptide chain release factor - - - - - - - - - - - - RF-1 k59_110673_1 1609634.A0A0C5AFV4_9VIRU 1.32e-31 123.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_110673_3 145579.C_BPPHM 2.64e-06 48.5 4QCC5@10239|Viruses,4QUKW@29258|ssDNA viruses,4QP4C@10841|Microviridae 10841|Microviridae S viral process - - - - - - - - - - - - - k59_144264_5 667014.Thein_1963 3.75e-45 162.0 COG4227@1|root,COG4227@2|Bacteria 2|Bacteria L nucleotidyltransferase activity traC - - - - - - - - - - - DUF1738,Toprim_3 k59_243078_1 1492738.FEM21_14470 5.55e-22 99.8 COG0037@1|root,COG0037@2|Bacteria,4PJWV@976|Bacteroidetes,1IE15@117743|Flavobacteriia,2NZMP@237|Flavobacterium 976|Bacteroidetes D tRNA processing - - - - - - - - - - - - - k59_77543_1 269799.Gmet_1537 1.69e-20 94.7 COG0714@1|root,COG0714@2|Bacteria,1QAW5@1224|Proteobacteria,42PY2@68525|delta/epsilon subdivisions,2WKGF@28221|Deltaproteobacteria,43TRR@69541|Desulfuromonadales 28221|Deltaproteobacteria S AAA domain (dynein-related subfamily) - - - ko:K04748 - - R00294 RC02794 ko00000 3.D.4.10 - - AAA_5,CbbQ_C k59_144265_1 490913.C4NTE0_9CAUD 1.61e-153 494.0 4QAXA@10239|Viruses,4QYJI@35237|dsDNA viruses no RNA stage,4QQ1A@28883|Caudovirales,4QNU7@10744|Podoviridae 10744|Podoviridae S metallopeptidase activity - - - - - - - - - - - - - k59_110766_1 1173029.JH980292_gene2855 1.14e-84 263.0 COG0675@1|root,COG0675@2|Bacteria,1G2IF@1117|Cyanobacteria,1HHGS@1150|Oscillatoriales 1117|Cyanobacteria L COG0675 Transposase and inactivated derivatives - - - - - - - - - - - - OrfB_IS605,OrfB_Zn_ribbon k59_44345_4 1187851.A33M_4269 2.27e-09 56.2 COG3514@1|root,COG3514@2|Bacteria,1N7KA@1224|Proteobacteria,2UGW1@28211|Alphaproteobacteria 28211|Alphaproteobacteria S BrnA antitoxin of type II toxin-antitoxin system - - - - - - - - - - - - BrnA_antitoxin k59_219128_2 1175654.A0A0S0N8I3_9CAUD 2.43e-64 224.0 4QCWX@10239|Viruses,4QYGT@35237|dsDNA viruses no RNA stage,4QU1G@28883|Caudovirales,4QMA7@10699|Siphoviridae 10699|Siphoviridae S Terminase-like family - - - - - - - - - - - - - k59_18870_4 136084.Q9G0F7_9CAUD 1.49e-56 207.0 4QH2I@10239|Viruses,4QWWD@35237|dsDNA viruses no RNA stage,4QQE9@28883|Caudovirales,4QNFX@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_201791_1 1429767.W6AQS6_9CAUD 9.99e-19 86.7 4QFP7@10239|Viruses,4QWTW@35237|dsDNA viruses no RNA stage,4QSRU@28883|Caudovirales,4QNWE@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - - - - - - - - - - - - - k59_201791_4 490913.C4NTC6_9CAUD 4.71e-40 140.0 4QAZ8@10239|Viruses,4R074@35237|dsDNA viruses no RNA stage,4QQTR@28883|Caudovirales,4QNX4@10744|Podoviridae 10744|Podoviridae S DNA mediated transformation - - - - - - - - - - - - - k59_35838_2 1379709.S5TMV0_9CIRC 5.53e-37 139.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_19535_1 1385658.U5KPZ6_9VIRU 1.27e-142 425.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_260885_1 1609634.A0A0C5AFV4_9VIRU 2.29e-22 96.7 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_260885_2 105154.Q9MBT9_9VIRU 8.41e-14 68.6 4QCC5@10239|Viruses,4QUKW@29258|ssDNA viruses,4QP4C@10841|Microviridae 10841|Microviridae S viral process - - - - - - - - - - - - - k59_177637_1 1220601.L7TML1_9CAUD 7.05e-18 84.7 4QFUK@10239|Viruses,4QYFH@35237|dsDNA viruses no RNA stage,4QRPY@28883|Caudovirales,4QIG8@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_102939_1 335543.Sfum_2504 4.37e-14 73.9 COG1948@1|root,COG1948@2|Bacteria,1N91Q@1224|Proteobacteria,42PBQ@68525|delta/epsilon subdivisions,2WJTC@28221|Deltaproteobacteria,2MRX3@213462|Syntrophobacterales 28221|Deltaproteobacteria L ERCC4 domain - - - - - - - - - - - - ERCC4 k59_185974_1 1476876.JOJO01000002_gene6625 1.09e-15 79.7 COG1088@1|root,COG1088@2|Bacteria,2GNDU@201174|Actinobacteria 2|Bacteria M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily rfbB - 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd k59_251791_2 1692249.A0A0K1RL40_9CIRC 7.28e-28 114.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_36399_1 316274.Haur_0564 6.24e-66 228.0 COG4373@1|root,COG4373@2|Bacteria 2|Bacteria - - gp17a - - ko:K06909 - - - - ko00000 - - - Terminase_6,Terminase_6C k59_36399_5 1151126.AQYI01000003_gene461 8.78e-26 114.0 COG0863@1|root,COG0863@2|Bacteria,2IM4X@201174|Actinobacteria,4FS7I@85023|Microbacteriaceae 201174|Actinobacteria L DNA methylase - - - - - - - - - - - - N6_N4_Mtase k59_11419_1 691965.D4P7I3_9CAUD 1.04e-69 236.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_102942_1 1165094.RINTHH_3920 3.27e-50 171.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_153341_1 1400520.LFAB_14450 0.000214 45.8 COG3093@1|root,COG3093@2|Bacteria,1V0AU@1239|Firmicutes,4HJU0@91061|Bacilli,3F6SR@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins higA - - ko:K18831 - - - - ko00000,ko02048,ko03000 - - - HTH_3,Peptidase_M78 k59_153341_2 525282.HMPREF0391_10162 2.9e-25 104.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,22GDX@1570339|Peptoniphilaceae 186801|Clostridia L snf2 family - - - - - - - - - - - - SNF2_N k59_36400_2 1437882.AZRU01000030_gene142 5.94e-09 60.8 COG0859@1|root,COG0859@2|Bacteria,1QUID@1224|Proteobacteria,1T204@1236|Gammaproteobacteria 1236|Gammaproteobacteria M COG0457 FOG TPR repeat - - - - - - - - - - - - Glyco_transf_9 k59_210315_1 1385658.U5KPZ6_9VIRU 1.82e-56 192.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_260890_3 91604.ID47_02985 6.79e-09 57.8 COG0507@1|root,COG0507@2|Bacteria,1R1AT@1224|Proteobacteria,2U1ZX@28211|Alphaproteobacteria 28211|Alphaproteobacteria L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD - - - - - - - - - - - - Terminase_6 k59_70005_1 2340.JV46_08010 5.05e-22 95.1 COG1917@1|root,COG1917@2|Bacteria,1PYID@1224|Proteobacteria,1SE9U@1236|Gammaproteobacteria,1J795@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Cupin 2, conserved barrel domain protein - - - - - - - - - - - - - k59_128671_1 1121396.KB892901_gene2246 3.01e-18 89.4 COG0745@1|root,COG2203@1|root,COG3852@1|root,COG4191@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG3852@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PAB@68525|delta/epsilon subdivisions,2WJ36@28221|Deltaproteobacteria,2MPRR@213118|Desulfobacterales 28221|Deltaproteobacteria T Sensory domain found in PocR - - - - - - - - - - - - HATPase_c,PAS_9,PocR,Response_reg k59_261004_2 856793.MICA_1841 1.57e-39 140.0 28HS3@1|root,2Z7ZE@2|Bacteria,1QH9A@1224|Proteobacteria,2TVB0@28211|Alphaproteobacteria,4BR65@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_19651_1 105154.Q9MBU6_9VIRU 3.54e-12 68.2 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_244437_1 1051675.G0YQI9_9CAUD 1.01e-23 102.0 4QF0B@10239|Viruses,4QX8P@35237|dsDNA viruses no RNA stage,4QSJT@28883|Caudovirales,4QNNK@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_79045_1 268746.Q58M60_BPPRM 0.000532 50.8 4QCIK@10239|Viruses,4QZTG@35237|dsDNA viruses no RNA stage,4QTSK@28883|Caudovirales,4QJ3M@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_235857_1 573174.M4MCV1_9VIRU 1.46e-17 82.0 4QAKZ@10239|Viruses,4QUSW@35237|dsDNA viruses no RNA stage 10239|Viruses S N-acetyltransferase activity - - - - - - - - - - - - - k59_154259_1 1232410.KI421417_gene2761 8.42e-28 116.0 COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,1R97W@1224|Proteobacteria 1224|Proteobacteria D Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_95288_2 932213.SPM24T3_13805 1.8e-45 163.0 COG5323@1|root,COG5410@1|root,COG5323@2|Bacteria,COG5410@2|Bacteria,1QWIG@1224|Proteobacteria,1T2W0@1236|Gammaproteobacteria 1236|Gammaproteobacteria S lysozyme - - - - - - - - - - - - - k59_20493_1 1477404.A0A023NGF5_9CAUD 5.45e-151 440.0 4QB3X@10239|Viruses,4QWKP@35237|dsDNA viruses no RNA stage,4QPEE@28883|Caudovirales,4QNCI@10744|Podoviridae 10744|Podoviridae S VWA-like domain (DUF2201) - - - - - - - - - - - - - k59_162676_1 1048834.TC41_2504 1.13e-26 107.0 2BH1N@1|root,32B21@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_204744_2 1197951.I6R9K8_9CAUD 1.37e-51 172.0 4QFIC@10239|Viruses,4QXG2@35237|dsDNA viruses no RNA stage,4QTVA@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_195506_2 1379725.S5TMY9_9CIRC 9.47e-48 169.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_6342_1 105154.Q9MBU0_9VIRU 6.96e-51 173.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_37980_7 1094556.MCY_00355 3.49e-08 59.7 COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,2TS8U@28211|Alphaproteobacteria,48T2N@772|Bartonellaceae 28211|Alphaproteobacteria I Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxD - 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Hexapep,Hexapep_2,LpxD k59_37980_9 1205680.CAKO01000029_gene5192 6.29e-07 54.3 COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2TRIQ@28211|Alphaproteobacteria,2JQZ9@204441|Rhodospirillales 204441|Rhodospirillales E Belongs to the DegT DnrJ EryC1 family - - - - - - - - - - - - DegT_DnrJ_EryC1 k59_104747_1 1403819.BATR01000081_gene2366 6.37e-24 106.0 COG0503@1|root,COG3170@1|root,COG0503@2|Bacteria,COG3170@2|Bacteria 2|Bacteria NU translation initiation factor activity apt - 2.4.2.7 ko:K00759,ko:K20541 ko00230,ko01100,map00230,map01100 - R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko02000,ko04147 4.D.3.1.6 - - Pribosyltran k59_262675_1 1165094.RINTHH_3920 2.7e-15 75.5 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_47512_1 1234888.K0A2J2_9VIRU 8.57e-29 114.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_171803_2 1321786.HMPREF1992_01756 1.58e-08 53.1 COG1551@1|root,COG1551@2|Bacteria,1VEEF@1239|Firmicutes 1239|Firmicutes T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding csrA - - ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 - - - ko00000,ko00001,ko03019 - - - CsrA k59_195509_1 1157708.KB907451_gene5046 1.89e-29 123.0 COG0616@1|root,COG0616@2|Bacteria,1QGPW@1224|Proteobacteria,2VJ0N@28216|Betaproteobacteria,4AB1E@80864|Comamonadaceae 28216|Betaproteobacteria OU PFAM peptidase S49 - - - - - - - - - - - - Peptidase_S49 k59_162678_2 421531.IX38_01905 3.22e-42 145.0 COG2856@1|root,COG2856@2|Bacteria,4NNFC@976|Bacteroidetes,1I29G@117743|Flavobacteriia,3ZRW9@59732|Chryseobacterium 976|Bacteroidetes E Macro domain - - - - - - - - - - - - Macro k59_162678_3 269799.Gmet_3140 9.75e-36 139.0 COG0338@1|root,COG3392@1|root,COG0338@2|Bacteria,COG3392@2|Bacteria,1P85S@1224|Proteobacteria 1224|Proteobacteria L site-specific DNA-methyltransferase (Adenine-specific) dam GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006281,GO:0006298,GO:0006304,GO:0006305,GO:0006306,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007049,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009007,GO:0009008,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0022402,GO:0032259,GO:0032775,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043412,GO:0043414,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044728,GO:0044786,GO:0044787,GO:0046483,GO:0048037,GO:0050662,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901576,GO:1901681,GO:1902292,GO:1902328,GO:1904047 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 k59_147458_2 145579.REP_BPPHM 9.64e-13 75.1 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_147458_4 1234888.K0A2J2_9VIRU 2.04e-27 110.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_37990_2 1618260.A0A0C5I2C5_9CIRC 3.95e-15 74.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_147459_2 588581.Cpap_1470 5.51e-07 52.0 2BZYB@1|root,331KR@2|Bacteria,1VFNJ@1239|Firmicutes,24HCE@186801|Clostridia,3WMG2@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_62580_1 1165094.RINTHH_3920 1.27e-44 156.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_222524_3 652103.Rpdx1_2982 6.03e-16 79.7 COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1QT50@1224|Proteobacteria,2TTND@28211|Alphaproteobacteria,3JW9V@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L TOPRIM - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - AAA_25,DnaB_C,Toprim_2,Toprim_4 k59_72503_1 546273.VEIDISOL_00706 6.17e-49 173.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4H2W4@909932|Negativicutes 909932|Negativicutes L SNF2 family - - - - - - - - - - - - Helicase_C,SNF2_N k59_205379_1 521674.Plim_4265 1.05e-08 65.1 29XN2@1|root,30JDF@2|Bacteria,2J498@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - k59_163208_1 1280952.HJA_12805 2.55e-07 56.2 COG0739@1|root,COG4219@1|root,COG0739@2|Bacteria,COG4219@2|Bacteria,1R8E7@1224|Proteobacteria,2TYFZ@28211|Alphaproteobacteria,43Y69@69657|Hyphomonadaceae 28211|Alphaproteobacteria KMT BlaR1 peptidase M56 - - - - - - - - - - - - Peptidase_M23,Peptidase_M56,TonB_C k59_180135_1 654929.REP_PCV1C 6.51e-27 114.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_180135_2 1692249.A0A0K1RLN8_9CIRC 6.22e-55 178.0 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_148152_1 887327.HMPREF0476_1911 4.36e-12 72.4 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2VJ57@28216|Betaproteobacteria,2KPWN@206351|Neisseriales 206351|Neisseriales L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_223071_1 1618248.A0A0C5IB82_9CIRC 3.15e-15 74.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_188947_1 1254432.SCE1572_26840 1.98e-13 76.3 COG4675@1|root,COG4675@2|Bacteria,1NFWC@1224|Proteobacteria 1224|Proteobacteria S tail collar domain protein - - - - - - - - - - - - Collar k59_131081_2 411460.RUMTOR_01350 2.76e-15 78.2 2EAAT@1|root,334F2@2|Bacteria,1VJJI@1239|Firmicutes,24TQU@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_196046_1 1385658.U5KPZ6_9VIRU 1.64e-85 270.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_105351_2 1788447.A0A190WHJ9_9CIRC 1.29e-42 147.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_21738_1 1437882.AZRU01000008_gene2966 9.23e-45 151.0 2DNA4@1|root,32WDI@2|Bacteria,1RH8K@1224|Proteobacteria,1S8YN@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage tail tube, TTP, lambda-like - - - - - - - - - - - - Phage_TTP_11 k59_21738_2 1123020.AUIE01000007_gene3223 8.11e-35 124.0 2CHRA@1|root,32S6D@2|Bacteria,1MZ8I@1224|Proteobacteria,1SHSQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage tail assembly chaperone, TAC - - - - - - - - - - - - Phage_TAC_13 k59_21738_4 351746.Pput_4103 3.19e-24 117.0 COG2911@1|root,COG5281@1|root,COG2911@2|Bacteria,COG5281@2|Bacteria,1QU6S@1224|Proteobacteria,1S7WY@1236|Gammaproteobacteria 1236|Gammaproteobacteria D tail tape measure protein - - - - - - - - - - - - SLT,Tape_meas_lam_C k59_105484_3 525903.Taci_1707 0.000295 51.6 COG0859@1|root,COG0859@2|Bacteria,3TAC6@508458|Synergistetes 508458|Synergistetes M family 9 - - - ko:K02843 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 k59_105484_4 316274.Haur_1031 3.44e-40 142.0 COG4627@1|root,COG4627@2|Bacteria 2|Bacteria - - - - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - Glycos_transf_2,Methyltransf_11,Methyltransf_23 k59_131213_1 349521.HCH_00790 9.39e-12 67.0 COG2404@1|root,COG2404@2|Bacteria,1MXEH@1224|Proteobacteria,1SADM@1236|Gammaproteobacteria 1236|Gammaproteobacteria S phosphoesterase DHHA1 - - - - - - - - - - - - DHHA1 k59_148329_1 1300345.LF41_2425 1.21e-56 190.0 COG1783@1|root,COG1783@2|Bacteria,1MWGP@1224|Proteobacteria,1RMTH@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_96619_1 357244.OTBS_1771 8.38e-51 167.0 arCOG06669@1|root,2ZC1E@2|Bacteria,1RBUZ@1224|Proteobacteria,2UIVS@28211|Alphaproteobacteria,47FQY@766|Rickettsiales 766|Rickettsiales - - - - - - - - - - - - - - - k59_73536_1 1121121.KB894304_gene3371 9.78e-07 58.5 COG5283@1|root,COG5283@2|Bacteria,1UHQM@1239|Firmicutes,4HGW7@91061|Bacilli,274AS@186822|Paenibacillaceae 91061|Bacilli S Phage-related minor tail protein - - - - - - - - - - - - Peptidase_M23,PhageMin_Tail,SLT k59_32688_1 1385658.U5KPZ6_9VIRU 3.44e-49 174.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_264259_1 1234888.K0A2J2_9VIRU 2.25e-147 436.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_246523_1 1536592.A0A088F773_9VIRU 6.01e-48 173.0 4QB5I@10239|Viruses 10239|Viruses S N-methyltransferase activity - - - - - - - - - - - - - k59_123763_3 585.DR95_1301 4.26e-36 127.0 COG3108@1|root,COG3108@2|Bacteria,1RICX@1224|Proteobacteria,1S6D5@1236|Gammaproteobacteria 1236|Gammaproteobacteria S peptidase M15 - - - ko:K17733 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M15_4 k59_230904_1 313596.RB2501_01425 8.31e-105 329.0 COG5545@1|root,COG5545@2|Bacteria,4PMA3@976|Bacteroidetes,1IJP7@117743|Flavobacteriia 976|Bacteroidetes L VirE N-terminal domain - - - - - - - - - - - - DUF3987,PriCT_2,VirE,VirE_N k59_57140_1 4929.XP_001486882.1 2.61e-29 120.0 COG5108@1|root,KOG1038@2759|Eukaryota,38EAY@33154|Opisthokonta,3NU1C@4751|Fungi,3QN4S@4890|Ascomycota,3RS68@4891|Saccharomycetes,479W3@766764|Debaryomycetaceae 4751|Fungi KL DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates - - 2.7.7.6 ko:K10908 - - - - ko00000,ko01000,ko03029 - - - RNA_pol,RPOL_N k59_32804_2 1382303.JPOM01000001_gene201 4.38e-07 55.8 COG3773@1|root,COG3773@2|Bacteria,1MWX3@1224|Proteobacteria,2TT15@28211|Alphaproteobacteria,2KGB3@204458|Caulobacterales 204458|Caulobacterales M cell wall hydrolase - - - - - - - - - - - - Hydrolase_2 k59_131952_1 1385658.U5KPZ6_9VIRU 5.03e-44 160.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_97349_2 1540257.JQMW01000013_gene731 4.23e-29 127.0 COG3941@1|root,COG5412@1|root,COG3941@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,247QT@186801|Clostridia 186801|Clostridia E Phage tail tape measure protein, TP901 family - - - - - - - - - - - - PhageMin_Tail k59_106271_1 652103.Rpdx1_2950 3.79e-67 221.0 COG4373@1|root,COG4373@2|Bacteria,1Q1RY@1224|Proteobacteria,2V9ED@28211|Alphaproteobacteria,3K5IV@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Mu-like prophage FluMu protein gp28 - - - - - - - - - - - - - k59_123888_2 1353531.AZNX01000020_gene4385 7.41e-55 178.0 COG1738@1|root,COG1738@2|Bacteria,1RDSF@1224|Proteobacteria 1224|Proteobacteria S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage - - - ko:K09125 - - - - ko00000 - - - Vut_1 k59_49477_1 1609634.A0A0C5AFV4_9VIRU 8e-38 140.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_181235_1 1385658.U5KPZ6_9VIRU 7.28e-88 278.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_131954_1 2003327.CAPSD_BPCHP 4.91e-51 182.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_254994_1 186617.M9M8L2_9VIRU 3.22e-35 134.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_181239_1 1380367.JIBC01000006_gene303 1.26e-18 90.5 28JKJ@1|root,2Z9DD@2|Bacteria,1MUN2@1224|Proteobacteria,2TST4@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Phage P22-like portal protein - - - - - - - - - - - - P22_portal k59_214302_9 1502724.FF80_01119 1.96e-06 50.4 COG1262@1|root,COG1262@2|Bacteria,1MZ25@1224|Proteobacteria,2TRJH@28211|Alphaproteobacteria,3N78T@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria S Sulfatase-modifying factor enzyme 1 - - 1.14.99.50 ko:K18912,ko:K20333 ko00340,ko02024,map00340,map02024 - R11013 RC03323,RC03324 ko00000,ko00001,ko01000 - - - FGE-sulfatase k59_40403_2 626887.J057_01685 4.64e-60 195.0 28HS3@1|root,2Z7ZE@2|Bacteria,1QH9A@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_231738_1 742733.HMPREF9469_05020 9.24e-149 499.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia,221IX@1506553|Lachnoclostridium 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_231738_2 742740.HMPREF9474_02263 2.47e-27 104.0 2ARVA@1|root,31H70@2|Bacteria,1V7JT@1239|Firmicutes,24JPE@186801|Clostridia,222RD@1506553|Lachnoclostridium 186801|Clostridia S Bacteriophage HK97-gp10, putative tail-component - - - - - - - - - - - - HK97-gp10_like k59_231738_3 1537917.JU82_06570 3.92e-36 131.0 2CGG9@1|root,2ZVSJ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_231738_5 742740.HMPREF9474_02267 7.47e-63 202.0 28NM4@1|root,2ZBMQ@2|Bacteria,1V1QD@1239|Firmicutes,24G1B@186801|Clostridia,221N8@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_231738_8 691965.D4P7D6_9CAUD 1.39e-125 394.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_231738_9 742740.HMPREF9474_02271 5.06e-112 343.0 28J3N@1|root,2Z8ZU@2|Bacteria,1V15Z@1239|Firmicutes,249Z0@186801|Clostridia,221RR@1506553|Lachnoclostridium 186801|Clostridia S Phage portal protein - - - - - - - - - - - - Phage_portal k59_181945_1 1609634.A0A0C5ANA6_9VIRU 1.29e-06 54.7 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_181945_2 1385658.U5KPZ6_9VIRU 3.13e-177 518.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_181945_4 105154.Q9MBU0_9VIRU 1.1e-28 119.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_239033_1 105154.Q9MBU6_9VIRU 6.81e-16 77.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_15487_2 349520.PPE_03799 9.63e-26 115.0 COG0463@1|root,COG0463@2|Bacteria,1TQEM@1239|Firmicutes,4H9X9@91061|Bacilli,26RHS@186822|Paenibacillaceae 91061|Bacilli M involved in cell wall biogenesis - - - - - - - - - - - - Glycos_transf_2,TPR_8 k59_106862_1 865861.AZSU01000001_gene227 8.06e-72 248.0 COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,36DHP@31979|Clostridiaceae 186801|Clostridia L DNA polymerase dnaE - 2.7.7.7 ko:K02337,ko:K14162 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k59_239040_1 796620.VIBC2010_10991 1.92e-10 66.2 COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,1RPA0@1236|Gammaproteobacteria,1XTSQ@135623|Vibrionales 135623|Vibrionales L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD recD - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,UvrD_C_2 k59_181953_1 1379719.S5TMX6_9CIRC 1.39e-32 128.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_255914_1 648996.Theam_0802 9.29e-14 76.6 COG1087@1|root,COG1087@2|Bacteria 2|Bacteria M UDP-glucose 4-epimerase activity galE - 5.1.3.2,5.1.3.25 ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 M00361,M00362,M00632 R00291,R02984,R10279 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd k59_255914_2 883080.HMPREF9697_00268 2.46e-13 73.6 COG0438@1|root,COG0438@2|Bacteria,1R1XI@1224|Proteobacteria,2TZ6P@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Methyltransferase FkbM domain - - - - - - - - - - - - Methyltransf_21 k59_214311_1 1108045.GORHZ_182_00100 3.96e-22 102.0 COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,2GJPX@201174|Actinobacteria,4GAV6@85026|Gordoniaceae 201174|Actinobacteria L ATP dependent DNA ligase C terminal region ligD GO:0000166,GO:0000287,GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0003896,GO:0003899,GO:0003909,GO:0003910,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0004652,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006269,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016874,GO:0016886,GO:0016895,GO:0017076,GO:0018130,GO:0019438,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0033554,GO:0034061,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0070566,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0097747,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 ko:K01971,ko:K10747 ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450 - R00381,R00382,R10822,R10823 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - DNA_ligase_A_C,DNA_ligase_A_M,LigD_N k59_98049_1 1498011.A0A096XUV3_9CAUD 2.52e-32 120.0 4QAUS@10239|Viruses,4QQ2S@28883|Caudovirales 28883|Caudovirales S flavin adenine dinucleotide binding - - - - - - - - - - - - - k59_98049_2 1980924.B2ZY70_9CAUD 8.47e-15 70.5 4QAZF@10239|Viruses,4QPH6@28883|Caudovirales 28883|Caudovirales S Protein of unknwon function (DUF3310) - - - - - - - - - - - - - k59_247482_1 913865.DOT_1568 3.73e-69 224.0 28MC2@1|root,2ZAQD@2|Bacteria,1VSEU@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - k59_89025_2 1123269.NX02_21835 0.000164 51.2 COG3023@1|root,COG3409@1|root,COG3023@2|Bacteria,COG3409@2|Bacteria,1RHPU@1224|Proteobacteria,2UA2W@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Putative peptidoglycan binding domain - - - - - - - - - - - - PG_binding_1 k59_24052_3 1110502.TMO_1566 1.94e-09 58.2 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,2U5BZ@28211|Alphaproteobacteria,2JRQZ@204441|Rhodospirillales 204441|Rhodospirillales L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_8385_1 373126.Q2A0C0_9VIRU 8.45e-34 138.0 4QCM6@10239|Viruses 10239|Viruses S actin binding - - - - - - - - - - - - - k59_257173_2 1692252.A0A0K1RL35_9CIRC 4.48e-93 285.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_132778_1 904144.AEJD01000006_gene558 7.91e-91 294.0 COG4626@1|root,COG4626@2|Bacteria,2GM6F@201174|Actinobacteria,4D088@85004|Bifidobacteriales 201174|Actinobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_41560_7 202956.BBNL01000066_gene214 8.68e-34 138.0 2D784@1|root,32TNH@2|Bacteria,1N098@1224|Proteobacteria,1SDM3@1236|Gammaproteobacteria,3NNDQ@468|Moraxellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_41560_8 1411685.U062_00586 2.31e-14 75.1 COG0433@1|root,COG0433@2|Bacteria,1QTVP@1224|Proteobacteria,1T1IQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Zonular occludens toxin (Zot) - - - ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko02042 - - - Zot k59_58120_1 1234888.K0A2J2_9VIRU 1.14e-47 170.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_248856_1 186617.M9MJB7_9VIRU 3.9e-06 55.1 4QB1C@10239|Viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_24988_2 1121935.AQXX01000096_gene2520 4.21e-14 84.0 COG4733@1|root,COG4733@2|Bacteria,1MXB4@1224|Proteobacteria,1RRUV@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Putative phage tail protein - - - - - - - - - - - - Phage-tail_3 k59_257177_1 246195.DNO_0743 1.66e-23 102.0 COG1783@1|root,COG1783@2|Bacteria,1R66A@1224|Proteobacteria,1RQFD@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage terminase, large subunit - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C k59_182590_1 266835.14027806 5.84e-25 109.0 2BHPF@1|root,32BSK@2|Bacteria,1QY4W@1224|Proteobacteria,2TXFM@28211|Alphaproteobacteria,43KPJ@69277|Phyllobacteriaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_99653_1 1234888.K0A2J2_9VIRU 9.09e-106 328.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_108031_1 595536.ADVE02000001_gene1129 1.37e-59 191.0 COG1351@1|root,COG1351@2|Bacteria,1MWY8@1224|Proteobacteria,2TTER@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant thyX - 2.1.1.148 ko:K03465 ko00240,ko00670,ko01100,map00240,map00670,map01100 - R06613 RC00022,RC00332 ko00000,ko00001,ko01000 - - - Thy1 k59_108031_2 1223523.H340_01189 2.02e-21 88.2 2E5GW@1|root,3308F@2|Bacteria,2GX64@201174|Actinobacteria 201174|Actinobacteria S Protein of unknwon function (DUF3310) - - - - - - - - - - - - DUF3310 k59_158167_1 655097.C8ZKI4_9CAUD 9.74e-94 290.0 4QEFX@10239|Viruses,4QYYG@35237|dsDNA viruses no RNA stage,4QRRV@28883|Caudovirales,4QNTK@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_183154_1 1609634.A0A0C5ANA6_9VIRU 5.2e-09 62.4 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_232923_2 1234888.K0A2J2_9VIRU 5.8e-153 451.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_249574_3 1122201.AUAZ01000017_gene2962 3.08e-15 86.7 COG4675@1|root,COG4675@2|Bacteria 2|Bacteria M tail collar domain protein - - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - Collar,Phage_fiber_2 k59_50582_1 1161935.H9D1E7_9CAUD 1.57e-65 220.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_241273_1 1268237.G114_16380 9.47e-14 76.3 2DPBK@1|root,331E1@2|Bacteria,1NCT1@1224|Proteobacteria,1SSKK@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_133560_1 1379698.RBG1_1C00001G1849 6.18e-07 51.2 COG3118@1|root,COG3118@2|Bacteria,2NPNZ@2323|unclassified Bacteria 2|Bacteria O Belongs to the thioredoxin family trxA - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin k59_133560_4 592029.DDD_2420 7.49e-08 55.8 COG0526@1|root,COG0526@2|Bacteria,4PDTT@976|Bacteroidetes,1IE7B@117743|Flavobacteriia,3HM2W@363408|Nonlabens 976|Bacteroidetes CO Thioredoxin - - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin k59_174655_1 1132855.KB913035_gene1251 2.73e-14 72.0 COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,2VHAZ@28216|Betaproteobacteria,2KM99@206350|Nitrosomonadales 206350|Nitrosomonadales OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins clpP - 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease k59_216564_2 102232.GLO73106DRAFT_00001460 1.79e-05 49.3 COG1403@1|root,COG3344@1|root,COG1403@2|Bacteria,COG3344@2|Bacteria,1G065@1117|Cyanobacteria 1117|Cyanobacteria L reverse transcriptase - - 2.7.7.49 ko:K00986 - - - - ko00000,ko01000 - - - GIIM,HNH,RVT_1,RVT_N k59_100302_1 490913.C4NTE0_9CAUD 9.09e-40 154.0 4QAXA@10239|Viruses,4QYJI@35237|dsDNA viruses no RNA stage,4QQ1A@28883|Caudovirales,4QNU7@10744|Podoviridae 10744|Podoviridae S metallopeptidase activity - - - - - - - - - - - - - k59_199789_1 665942.HMPREF1022_03280 1.02e-20 95.9 2DUXE@1|root,32UY2@2|Bacteria,1N2YI@1224|Proteobacteria,430A8@68525|delta/epsilon subdivisions,2WVIN@28221|Deltaproteobacteria,2MCZ8@213115|Desulfovibrionales 28221|Deltaproteobacteria S Phage T7 capsid assembly protein - - - - - - - - - - - - Phage_T7_Capsid k59_199789_2 1500301.JQMF01000006_gene1755 7.86e-88 278.0 28MSK@1|root,2ZB0X@2|Bacteria,1R7CY@1224|Proteobacteria,2U2MY@28211|Alphaproteobacteria,4BJ92@82115|Rhizobiaceae 28211|Alphaproteobacteria S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_224730_2 1502851.FG93_03501 2.36e-34 126.0 2AGTB@1|root,3171D@2|Bacteria,1RJGM@1224|Proteobacteria,2UJ68@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_224730_3 1220601.L7TLW2_9CAUD 5.62e-37 146.0 4QASG@10239|Viruses,4QZZU@35237|dsDNA viruses no RNA stage,4QT37@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_17197_2 102125.Xen7305DRAFT_00046030 1.17e-30 127.0 COG0457@1|root,COG0457@2|Bacteria,1G3MN@1117|Cyanobacteria 1117|Cyanobacteria K PFAM sulfotransferase - - - - - - - - - - - - Sulfotransfer_1,TPR_1,TPR_11,TPR_2,TPR_8 k59_17197_7 1282876.BAOK01000001_gene2713 5.9e-07 58.9 COG0110@1|root,COG0673@1|root,COG0110@2|Bacteria,COG0673@2|Bacteria,1MZV9@1224|Proteobacteria,2TWJW@28211|Alphaproteobacteria,4BR7B@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S Hexapeptide repeat of succinyl-transferase - - 2.3.1.201 ko:K13018 ko00520,map00520 - R10100 RC00004,RC00166 ko00000,ko00001,ko01000,ko01005 - - - GFO_IDH_MocA,Hexapep,Hexapep_2 k59_92783_1 1120971.AUCA01000053_gene371 5.41e-67 211.0 COG0863@1|root,COG0863@2|Bacteria,1UZIN@1239|Firmicutes,4HU16@91061|Bacilli 91061|Bacilli L DNA methylase - - - - - - - - - - - - N6_N4_Mtase k59_1856_1 1618238.A0A0C5IB41_9CIRC 3.52e-112 338.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_151028_2 547144.HydHO_0135 6.2e-40 150.0 COG0305@1|root,COG0305@2|Bacteria,2G3QP@200783|Aquificae 200783|Aquificae L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_142804_3 1385658.U5KPZ6_9VIRU 1.6e-47 170.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_158847_1 2003327.CAPSD_BPCHP 9.3e-84 267.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_158847_5 1609634.A0A0C5AFT2_9VIRU 4.01e-81 255.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_158847_7 1609634.A0A0C5AFV4_9VIRU 2.02e-91 289.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_175466_1 428125.CLOLEP_01375 2.3e-26 112.0 2EWZQ@1|root,33QB0@2|Bacteria,1V0T1@1239|Firmicutes,249Z2@186801|Clostridia,3WNBH@541000|Ruminococcaceae 186801|Clostridia S DNA polymerase type-B family - - - - - - - - - - - - - k59_134444_1 1788452.A0A190WHG0_9CIRC 5.96e-49 171.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_84370_2 1234888.K0A2J2_9VIRU 2.9e-44 159.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_241954_2 1385658.U5KPZ6_9VIRU 2.79e-83 266.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_158853_1 145579.B_BPPHM 2.35e-20 87.8 4QDBB@10239|Viruses,4QUM0@29258|ssDNA viruses,4QP4D@10841|Microviridae 10841|Microviridae S Chlamydia-phage Chp2 scaffold (Chlamy_scaf) - - - - - - - - - - - - - k59_26725_8 1636271.A0A0E3JI89_9CAUD 1.86e-18 83.6 4QH9H@10239|Viruses,4QTW5@28883|Caudovirales,4QN1C@10699|Siphoviridae 10699|Siphoviridae S kinase activity - - - - - - - - - - - - - k59_151179_1 553217.ENHAE0001_1429 1.16e-161 462.0 COG5527@1|root,COG5527@2|Bacteria,1PR7P@1224|Proteobacteria,1TB4K@1236|Gammaproteobacteria,3NR9Q@468|Moraxellaceae 1236|Gammaproteobacteria L Initiator Replication protein - - - - - - - - - - - - Rep_3 k59_151179_3 1002339.HMPREF9373_2624 7.25e-147 441.0 COG0507@1|root,COG0507@2|Bacteria,1MUTR@1224|Proteobacteria,1RQS3@1236|Gammaproteobacteria,3NJSK@468|Moraxellaceae 1236|Gammaproteobacteria L MobA/MobL family - - - - - - - - - - - - MobA_MobL k59_43363_2 999630.TUZN_0126 3.31e-10 65.1 COG1533@1|root,arCOG01290@2157|Archaea,2XPRN@28889|Crenarchaeota 28889|Crenarchaeota L PFAM Radical SAM domain protein - - - - - - - - - - - - Radical_SAM k59_60383_2 2055.JNXA01000005_gene549 9.13e-07 54.7 COG0860@1|root,COG3409@1|root,COG0860@2|Bacteria,COG3409@2|Bacteria,2GPA9@201174|Actinobacteria,4GC3U@85026|Gordoniaceae 201174|Actinobacteria M Ami_3 cwlM GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3,PG_binding_1 k59_185009_1 1196028.ALEF01000025_gene1643 2.47e-07 57.4 COG1051@1|root,COG1051@2|Bacteria,1V3T8@1239|Firmicutes,4HH2F@91061|Bacilli,4C6SQ@84406|Virgibacillus 91061|Bacilli F NUDIX domain - - - - - - - - - - - - NUDIX k59_260044_1 1476973.JMMB01000006_gene3329 1.59e-15 75.1 2DRAR@1|root,33AZK@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_260044_2 768671.ThimaDRAFT_1884 1.92e-07 55.8 COG1846@1|root,COG1846@2|Bacteria,1QZVB@1224|Proteobacteria,1T5B5@1236|Gammaproteobacteria,1X2W2@135613|Chromatiales 1224|Proteobacteria K PFAM HTH transcriptional regulator, MarR - - - - - - - - - - - - HTH_36 k59_192896_1 511.JT27_18240 5.8e-15 78.2 COG4106@1|root,COG4106@2|Bacteria 2|Bacteria FG trans-aconitate 2-methyltransferase activity - - 2.1.1.197 ko:K02169 ko00780,ko01100,map00780,map01100 M00572 R09543 RC00003,RC00460 ko00000,ko00001,ko00002,ko01000 - - - Dimerisation2,Methyltransf_11,Methyltransf_2,Methyltransf_23,Methyltransf_25,NodS k59_192896_4 1348657.M622_05675 2.76e-53 184.0 COG3179@1|root,COG3179@2|Bacteria,1RE5T@1224|Proteobacteria,2VSTB@28216|Betaproteobacteria 28216|Betaproteobacteria S chitinase - - - - - - - - - - - - Glyco_hydro_19 k59_226826_1 1986029.Q9MBM8_9VIRU 1.15e-88 289.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_169015_1 1692244.A0A0K1RLR5_9CIRC 2.5e-74 234.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_260208_3 93220.LV28_24555 5.7e-76 238.0 COG0338@1|root,COG0338@2|Bacteria,1P85S@1224|Proteobacteria,2VNFF@28216|Betaproteobacteria,1K7JE@119060|Burkholderiaceae 28216|Betaproteobacteria L D12 class N6 adenine-specific DNA methyltransferase - - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 k59_28159_1 1120963.KB894518_gene2794 7.47e-34 135.0 COG0749@1|root,COG0749@2|Bacteria,1MWX7@1224|Proteobacteria,1S0Q1@1236|Gammaproteobacteria 1236|Gammaproteobacteria L ORF located using Glimmer RBSfinder - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A,DNA_pol_A_exo1 k59_251146_7 762903.Pedsa_3094 2.18e-17 76.6 2C8RN@1|root,32RMQ@2|Bacteria,4NSD0@976|Bacteroidetes,1IUGX@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_219190_1 928210.CALU01000071_gene475 2.27e-41 150.0 28MVD@1|root,2ZB2Y@2|Bacteria,1R8NK@1224|Proteobacteria,2U265@28211|Alphaproteobacteria,48TMW@772|Bartonellaceae 28211|Alphaproteobacteria S to expressed protein Bartonella henselae str. Houston-1 gi 49238873 emb CAF28166.1 - - - - - - - - - - - - DUF4043 k59_219190_3 360095.BARBAKC583_0228 7.26e-28 120.0 COG3170@1|root,COG3170@2|Bacteria,1R69E@1224|Proteobacteria,2U3B9@28211|Alphaproteobacteria,48TPA@772|Bartonellaceae 28211|Alphaproteobacteria NU Phage P22-like portal protein - - - - - - - - - - - - P22_portal k59_127662_1 1279017.AQYJ01000014_gene3004 3.22e-22 107.0 COG4733@1|root,COG4733@2|Bacteria,1R77Q@1224|Proteobacteria 1224|Proteobacteria D nuclear chromosome segregation - - - - - - - - - - - - - k59_119306_2 1788454.A0A190WHE4_9CIRC 1.25e-41 149.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_78397_1 1294142.CINTURNW_4063 8.06e-11 73.6 COG1216@1|root,COG1216@2|Bacteria,1V06G@1239|Firmicutes,247WU@186801|Clostridia,36GAS@31979|Clostridiaceae 186801|Clostridia H glycosyl transferase family - - - - - - - - - - - - Glycos_transf_2,Methyltransf_23 k59_94516_1 1219035.NT2_13_00580 5.08e-28 116.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_4447_1 1197951.I6R9K8_9CAUD 4.95e-59 193.0 4QFIC@10239|Viruses,4QXG2@35237|dsDNA viruses no RNA stage,4QTVA@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_103046_3 691965.D4P7I3_9CAUD 5.63e-236 695.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_11584_1 233412.HD_1555 4.43e-60 204.0 COG4373@1|root,COG4373@2|Bacteria,1N2KG@1224|Proteobacteria,1RNKU@1236|Gammaproteobacteria,1Y827@135625|Pasteurellales 135625|Pasteurellales S Terminase-like family - - - - - - - - - - - - Terminase_6 k59_220374_2 1673638.A0A0H4AJL5_9CIRC 6.62e-48 168.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_45414_1 1007105.PT7_P071 7.05e-10 64.7 28N2X@1|root,2ZB8P@2|Bacteria,1R4KJ@1224|Proteobacteria,2WDTP@28216|Betaproteobacteria,3T8AJ@506|Alcaligenaceae 28216|Betaproteobacteria S sty2063 SWALL Q8Z5Z8 (EMBL AL627272) (262 aa) fasta scores E() 1.5e-07, 24.43 id in 266 aa, and to Escherichia coli O157 H7 - - - - - - - - - - - - - k59_94531_1 438753.AZC_3598 3.23e-63 213.0 COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1QT52@1224|Proteobacteria,2TVNI@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Toprim-like - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - DnaB_C,Toprim_2 k59_145397_6 398578.Daci_3225 6.19e-24 93.6 2EI4V@1|root,33BW7@2|Bacteria,1NN3Z@1224|Proteobacteria 1224|Proteobacteria S Protein of unknwon function (DUF3310) - - - - - - - - - - - - DUF3310 k59_145397_10 1556290.A0A0A0RM00_9CAUD 6.12e-49 174.0 4QAXQ@10239|Viruses,4QRFY@28883|Caudovirales,4QM52@10699|Siphoviridae 10699|Siphoviridae S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor - - - - - - - - - - - - - k59_177852_1 1267535.KB906767_gene157 1.31e-26 106.0 COG1215@1|root,COG1215@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Glyco_tranf_2_4 k59_177852_2 1045856.EcWSU1_01383 4.39e-20 92.4 COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,1RNWN@1236|Gammaproteobacteria,3X12T@547|Enterobacter 1236|Gammaproteobacteria H Catalyzes the reversible formation of fructose 6- phosphate from dihydroxyacetone and D-glyceraldehyde 3-phosphate via an aldolization reaction fsaA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016832,GO:0044424,GO:0044464,GO:0097023 - ko:K08313,ko:K08314 - - - - ko00000,ko01000 - - iEC042_1314.EC042_0914,iSBO_1134.SBO_0715,iSF_1195.SF0775,iSFxv_1172.SFxv_0845,iS_1188.S0818 TAL_FSA k59_5724_1 1144310.PMI07_002360 1.6e-05 52.8 2DPZ1@1|root,3340X@2|Bacteria,1R2EE@1224|Proteobacteria,2TZIB@28211|Alphaproteobacteria,4BP2Q@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_204203_2 1122223.KB890687_gene2916 1.5e-08 58.5 COG3864@1|root,COG3864@2|Bacteria,1WME0@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S Putative metallopeptidase domain - - - - - - - - - - - - DUF2201,DUF2201_N k59_137940_1 742740.HMPREF9474_02272 1.8e-58 198.0 COG4626@1|root,COG4626@2|Bacteria,1TT9I@1239|Firmicutes,24AFK@186801|Clostridia,222GA@1506553|Lachnoclostridium 186801|Clostridia S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_137940_2 411460.RUMTOR_01350 3.05e-12 70.9 2EAAT@1|root,334F2@2|Bacteria,1VJJI@1239|Firmicutes,24TQU@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_137944_2 1301098.PKB_0742 6.47e-37 133.0 2DMKC@1|root,32S64@2|Bacteria,1N3QF@1224|Proteobacteria,1S8NZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S HNH endonuclease - - - - - - - - - - - - HNH_3 k59_179085_2 111781.Lepto7376_3538 0.000323 50.8 COG2931@1|root,COG2931@2|Bacteria,1G69X@1117|Cyanobacteria,1HAQZ@1150|Oscillatoriales 1117|Cyanobacteria Q COGs COG2931 RTX toxins and related Ca2 -binding protein - - - - - - - - - - - - HemolysinCabind,Lectin_C k59_47103_2 1121949.AQXT01000002_gene1040 6.65e-48 159.0 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,2U5BZ@28211|Alphaproteobacteria,43XK6@69657|Hyphomonadaceae 28211|Alphaproteobacteria L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_47103_4 172088.AUGA01000017_gene2380 4.4e-41 148.0 COG3206@1|root,COG3206@2|Bacteria,1ND5H@1224|Proteobacteria,2UIQZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria M protein involved in exopolysaccharide biosynthesis - - - - - - - - - - - - - k59_47103_5 1545915.JROG01000009_gene2733 6.68e-08 55.5 29B7J@1|root,2ZY5Y@2|Bacteria,1NND5@1224|Proteobacteria,2UKRN@28211|Alphaproteobacteria,2K8CI@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - k59_5908_1 186617.M9M8L2_9VIRU 3.54e-19 94.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_55149_1 1541883.A0A088FVG5_9CAUD 1e-68 231.0 4QAZJ@10239|Viruses,4QPFF@28883|Caudovirales,4QJS9@10662|Myoviridae 10662|Myoviridae S virion assembly - - - - - - - - - - - - - k59_47108_1 553217.ENHAE0001_2186 1.43e-39 144.0 28J3M@1|root,2Z8ZT@2|Bacteria,1Q2A4@1224|Proteobacteria,1RSHA@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_154836_1 591167.Sfla_3672 5.09e-57 187.0 COG0270@1|root,COG0270@2|Bacteria,2GNB2@201174|Actinobacteria 201174|Actinobacteria L DNA (cytosine-5-)-methyltransferase activity - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_5909_1 749222.Nitsa_1823 2.04e-30 118.0 COG0270@1|root,COG0270@2|Bacteria,1N0XD@1224|Proteobacteria 1224|Proteobacteria H C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_180065_3 1609634.A0A0C5AFV4_9VIRU 1.11e-147 442.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_139165_1 1429916.X566_04570 6.95e-55 200.0 2F84W@1|root,340I7@2|Bacteria,1R3XR@1224|Proteobacteria,2U20U@28211|Alphaproteobacteria,3JVBF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_148276_1 1475143.W8SNN0_9CIRC 1.15e-34 135.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_7206_1 1028800.RG540_CH13920 9.09e-15 79.7 COG0741@1|root,COG0741@2|Bacteria,1R251@1224|Proteobacteria,2U9N4@28211|Alphaproteobacteria,4BGQJ@82115|Rhizobiaceae 28211|Alphaproteobacteria M lytic transglycosylase activity - - - - - - - - - - - - - k59_230072_2 1120949.KB903356_gene8520 4.37e-08 62.8 COG1573@1|root,COG1573@2|Bacteria,2GMPT@201174|Actinobacteria,4DA7F@85008|Micromonosporales 201174|Actinobacteria L Uracil-DNA glycosylase dpo - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k59_122919_2 1692249.A0A0K1RLN8_9CIRC 1.52e-50 171.0 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_254091_1 1481785.A0A068Q5W4_9CAUD 3.74e-09 62.8 4QAUT@10239|Viruses,4QVIM@35237|dsDNA viruses no RNA stage,4QQ7X@28883|Caudovirales,4QNET@10744|Podoviridae 10744|Podoviridae S DNA ligase (ATP) activity - - - - - - - - - - - - - k59_48298_1 1609634.A0A0C5AFT2_9VIRU 3.5e-38 140.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_263376_1 1122201.AUAZ01000021_gene3157 1.89e-07 55.1 2EXSU@1|root,33R23@2|Bacteria,1NS77@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_205521_2 716928.AJQT01000109_gene1217 4.23e-36 128.0 2FEUE@1|root,346TC@2|Bacteria,1MZPB@1224|Proteobacteria,2UC4Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_156758_1 242527.Q6V7L9_9CAUD 2.33e-31 143.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QNG7@10744|Podoviridae 10744|Podoviridae S lytic transglycosylase activity - GO:0008150,GO:0016032,GO:0019058,GO:0030260,GO:0039678,GO:0044403,GO:0044409,GO:0044411,GO:0044419,GO:0046718,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0051830,GO:0085027 - - - - - - - - - - - k59_156758_4 194966.Q7Y5M4_BPSP6 3.52e-39 134.0 4QB6G@10239|Viruses,4QVYX@35237|dsDNA viruses no RNA stage,4QQS8@28883|Caudovirales,4QNR7@10744|Podoviridae 10744|Podoviridae S Peptidase M15 - - - - - - - - - - - - - k59_156758_7 998674.ATTE01000001_gene1620 1.1e-66 221.0 COG2356@1|root,COG2356@2|Bacteria,1MXQM@1224|Proteobacteria,1RPX9@1236|Gammaproteobacteria,462WI@72273|Thiotrichales 72273|Thiotrichales L Endonuclease I - - - - - - - - - - - - Endonuclease_1 k59_156758_10 1122599.AUGR01000024_gene1352 8.74e-68 212.0 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria,1XJHS@135619|Oceanospirillales 135619|Oceanospirillales L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_156758_12 910964.GEAM_4276 8.92e-66 216.0 COG2974@1|root,COG2974@2|Bacteria,1RCPA@1224|Proteobacteria,1S3HW@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Putative exonuclease, RdgC - - - - - - - - - - - - RdgC k59_156758_16 1168281.I3PUZ3_9CAUD 8.47e-47 165.0 4QGDF@10239|Viruses,4R0KW@35237|dsDNA viruses no RNA stage,4QSIJ@28883|Caudovirales,4QP3J@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_156758_17 492774.JQMB01000013_gene3074 9.57e-20 90.1 COG1476@1|root,COG1476@2|Bacteria,1PKWU@1224|Proteobacteria,2UZIP@28211|Alphaproteobacteria,4BF5R@82115|Rhizobiaceae 28211|Alphaproteobacteria K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 k59_231062_2 255131.Q6JIG5_9CAUD 4.09e-52 168.0 4QC6A@10239|Viruses,4QWAW@35237|dsDNA viruses no RNA stage,4QPWF@28883|Caudovirales,4QMHG@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_264421_1 428125.CLOLEP_01400 2.74e-62 217.0 28JED@1|root,2Z98K@2|Bacteria,1TW1U@1239|Firmicutes,24CFD@186801|Clostridia,3WNW0@541000|Ruminococcaceae 186801|Clostridia K Bacterial regulatory proteins, luxR family - - - - - - - - - - - - GerE k59_149248_1 1788454.A0A190WHE4_9CIRC 3.54e-41 146.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_14683_1 700598.Niako_7157 3.1e-10 68.9 COG4886@1|root,COG4886@2|Bacteria 2|Bacteria S regulation of response to stimulus - - - - - - - - - - - - Flg_new,LRR_5,MucBP k59_106330_3 269796.Rru_A1278 5.74e-19 88.6 28N1N@1|root,2ZB7Q@2|Bacteria,1R86T@1224|Proteobacteria,2U0A6@28211|Alphaproteobacteria,2JRMI@204441|Rhodospirillales 204441|Rhodospirillales H Sulfotransferase domain - - - - - - - - - - - - Sulfotransfer_1 k59_97427_2 932213.SPM24T3_23272 1.43e-35 133.0 COG4695@1|root,COG4695@2|Bacteria,1N389@1224|Proteobacteria,1SNRA@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Portal protein - - - - - - - - - - - - - k59_97428_2 172088.AUGA01000033_gene4632 5.9e-24 99.4 28MVD@1|root,2ZB2Y@2|Bacteria,1R8NK@1224|Proteobacteria,2U265@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF4043) - - - - - - - - - - - - DUF4043 k59_190485_3 136993.KB900626_gene2756 2.9e-07 58.5 COG2369@1|root,COG2369@2|Bacteria 2|Bacteria K cell adhesion yqbB3 - - - - - - - - - - - Phage_Mu_F,Phage_portal k59_190485_4 1327981.S0A2G1_9CAUD 9.61e-129 389.0 4QAYV@10239|Viruses,4QUZ7@35237|dsDNA viruses no RNA stage,4QPU3@28883|Caudovirales,4QKKX@10699|Siphoviridae 10699|Siphoviridae S Phage portal protein - - - - - - - - - - - - - k59_190485_5 246194.CHY_1680 4.51e-11 65.5 COG1783@1|root,COG1783@2|Bacteria,1TRQP@1239|Firmicutes,248E9@186801|Clostridia,42I1E@68295|Thermoanaerobacterales 186801|Clostridia S Terminase RNAseH like domain - - - ko:K06909 - - - - ko00000 - - - Terminase_2,Terminase_3,Terminase_3C k59_82743_1 1122609.AUGT01000008_gene2868 1.64e-26 116.0 COG0366@1|root,COG0515@1|root,COG2133@1|root,COG3227@1|root,COG4733@1|root,COG0366@2|Bacteria,COG0515@2|Bacteria,COG2133@2|Bacteria,COG3227@2|Bacteria,COG4733@2|Bacteria 2|Bacteria S cellulase activity - - 3.2.1.3 ko:K01178,ko:K14645,ko:K18546 ko00500,ko01100,ko02024,map00500,map01100,map02024 - R01790,R01791,R06199 - ko00000,ko00001,ko01000,ko01002,ko03110 - GH15 - Alpha-amylase,GSDH,He_PIG,PKD,Pro_Al_protease,SLH,Trypsin,fn3 k59_65389_2 1385658.U5KPZ6_9VIRU 4.08e-23 99.4 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_214839_1 1385658.U5KPZ6_9VIRU 8.18e-63 218.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_65403_1 1121448.DGI_3362 1.5e-37 139.0 COG1705@1|root,COG1705@2|Bacteria,1Q53D@1224|Proteobacteria,43EUQ@68525|delta/epsilon subdivisions,2X19Y@28221|Deltaproteobacteria,2MEK3@213115|Desulfovibrionales 28221|Deltaproteobacteria NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase - - - - - - - - - - - - Amidase_3,Glucosaminidase k59_82759_3 94624.Bpet4545 5.83e-06 49.3 COG3311@1|root,COG3311@2|Bacteria,1NGB9@1224|Proteobacteria 1224|Proteobacteria K Transcriptional regulator - - - ko:K07733 - - - - ko00000,ko03000 - - - Phage_AlpA k59_256514_2 1057002.KB905370_gene2867 1.55e-60 202.0 COG0330@1|root,COG0330@2|Bacteria,1N5JY@1224|Proteobacteria,2TUCR@28211|Alphaproteobacteria,4BAPA@82115|Rhizobiaceae 28211|Alphaproteobacteria O prohibitin homologues - - - - - - - - - - - - Band_7 k59_264995_2 1234888.K0A2J2_9VIRU 2.6e-121 371.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_239733_1 1618248.A0A0C5IB82_9CIRC 1.63e-14 73.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_107227_1 78245.Xaut_3704 1.52e-88 273.0 COG5323@1|root,COG5323@2|Bacteria,1MW8S@1224|Proteobacteria,2TREI@28211|Alphaproteobacteria,3EYR8@335928|Xanthobacteraceae 28211|Alphaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_239943_1 948071.S4S2L2_9CAUD 3.22e-05 56.2 4QHQ5@10239|Viruses,4QR7K@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_89524_1 582899.Hden_3445 1.07e-55 184.0 COG4249@1|root,COG4249@2|Bacteria,1QPXG@1224|Proteobacteria,2U1JQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S peptidase - - - - - - - - - - - - Peptidase_C14 k59_89524_2 40373.F991_00514 6.99e-53 173.0 2E66S@1|root,330VB@2|Bacteria,1N0WA@1224|Proteobacteria 1224|Proteobacteria S TIR domain - - - - - - - - - - - - TIR_2 k59_89524_3 335284.Pcryo_2482 2.67e-171 480.0 COG2197@1|root,COG2197@2|Bacteria,1N33D@1224|Proteobacteria,1RZCA@1236|Gammaproteobacteria,3NNFM@468|Moraxellaceae 1236|Gammaproteobacteria KT Primase C terminal 1 (PriCT-1) - - - - - - - - - - - - HTH_23,PriCT_1,Replicase k59_65666_1 691966.D4P728_9CAUD 1.86e-06 57.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_198741_2 1618260.A0A0C5I2C5_9CIRC 4.04e-20 91.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_50050_58 583355.Caka_0498 3.38e-07 52.4 COG2197@1|root,COG2197@2|Bacteria,46SQZ@74201|Verrucomicrobia,3K9MY@414999|Opitutae 414999|Opitutae K Two component transcriptional regulator, LuxR family - - - - - - - - - - - - GerE,Response_reg k59_50050_62 753085.F4YCV3_9CAUD 4.9e-152 473.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_133259_1 1121459.AQXE01000001_gene2774 2.3e-120 387.0 COG5108@1|root,COG5108@2|Bacteria,1PIWB@1224|Proteobacteria,42YXG@68525|delta/epsilon subdivisions,2WU1V@28221|Deltaproteobacteria,2M9ED@213115|Desulfovibrionales 28221|Deltaproteobacteria K DNA-dependent RNA polymerase - - - - - - - - - - - - RNA_pol,RPOL_N k59_182926_2 398578.Daci_3449 6.52e-09 65.5 COG3209@1|root,COG3209@2|Bacteria,1NF2V@1224|Proteobacteria,2WF0C@28216|Betaproteobacteria,4AJQE@80864|Comamonadaceae 28216|Betaproteobacteria M Concanavalin A-like lectin/glucanases superfamily - - - - - - - - - - - - Laminin_G_3 k59_257615_1 563192.HMPREF0179_03424 4.24e-56 196.0 COG5410@1|root,COG5410@2|Bacteria,1N0W2@1224|Proteobacteria,42YNM@68525|delta/epsilon subdivisions,2WU2R@28221|Deltaproteobacteria,2MAIS@213115|Desulfovibrionales 28221|Deltaproteobacteria K chromosome segregation - - - - - - - - - - - - - k59_149763_1 66366.REP_TYLCI 1.94e-19 89.0 4QB6C@10239|Viruses,4QUKM@29258|ssDNA viruses 10239|Viruses J Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_116588_2 1618248.A0A0C5IB82_9CIRC 6.25e-83 259.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_216175_1 1169152.AXVD01000057_gene1002 5.95e-10 63.5 COG0207@1|root,COG0207@2|Bacteria,2GKY0@201174|Actinobacteria,4G5DA@85025|Nocardiaceae 201174|Actinobacteria F Thymidylate synthase - - 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt k59_42029_4 996306.SSUR61_0253 1.81e-28 116.0 2E1MQ@1|root,32WYT@2|Bacteria,1VB8R@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - k59_58522_2 1038860.AXAP01000007_gene6071 2.59e-38 146.0 COG0741@1|root,COG0741@2|Bacteria,1MX5R@1224|Proteobacteria,2TVHC@28211|Alphaproteobacteria,3JUU6@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Transglycosylase SLT domain - - - - - - - - - - - - SLT k59_240947_1 1609634.A0A0C5AFV4_9VIRU 3.08e-25 104.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_240947_3 1385658.U5KNR1_9VIRU 9.05e-64 209.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_240947_7 105154.Q9MBU6_9VIRU 8.49e-184 532.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_224409_1 1465639.A0A060BS47_9CAUD 8.82e-12 72.0 4QB0J@10239|Viruses,4QZQE@35237|dsDNA viruses no RNA stage,4QQ11@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_83427_2 768066.HELO_2643 6.29e-45 160.0 28JC4@1|root,2Z96S@2|Bacteria,1RI8W@1224|Proteobacteria,1S6FI@1236|Gammaproteobacteria 1236|Gammaproteobacteria S P22 coat protein-protein 5 domain protein - - - - - - - - - - - - - k59_141491_1 102129.Lepto7375DRAFT_7444 5.5e-39 142.0 COG0270@1|root,COG0270@2|Bacteria 2|Bacteria L DNA (cytosine-5-)-methyltransferase activity - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_75183_1 1609634.A0A0C5ANA6_9VIRU 9.26e-30 117.0 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_117486_2 586413.CCDL010000004_gene3495 7.01e-08 57.4 COG3409@1|root,COG3409@2|Bacteria,1VG7I@1239|Firmicutes,4ITUA@91061|Bacilli 91061|Bacilli M Putative peptidoglycan binding domain - - - - - - - - - - - - Glyco_hydro_25,PG_binding_1 k59_225248_1 1609634.A0A0C5AFV4_9VIRU 1.81e-44 159.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_42795_1 1408428.JNJP01000012_gene1111 1.1e-32 130.0 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1NKZK@1224|Proteobacteria,42QC5@68525|delta/epsilon subdivisions,2WVD2@28221|Deltaproteobacteria,2MCDS@213115|Desulfovibrionales 28221|Deltaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_158578_2 1234888.K0A2J2_9VIRU 3.04e-129 390.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_67605_1 1218075.BAYA01000001_gene423 3.83e-18 80.1 2D1MV@1|root,32TAZ@2|Bacteria,1N45A@1224|Proteobacteria,2VX6Y@28216|Betaproteobacteria 28216|Betaproteobacteria S Phage protein (N4 Gp49/phage Sf6 gene 66) family - - - - - - - - - - - - Phage_gp49_66 k59_233283_1 1462527.CCDM010000003_gene3727 5.25e-26 115.0 COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,1UHQM@1239|Firmicutes,4HGW7@91061|Bacilli,23KG0@182709|Oceanobacillus 91061|Bacilli D Phage-related minor tail protein - - - - - - - - - - - - Peptidase_M23,PhageMin_Tail,SLT k59_217146_2 1986029.Q9MBM3_9VIRU 6.75e-40 146.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_241668_1 942165.E9KIG0_9CAUD 9.86e-12 70.5 4QAM2@10239|Viruses,4QV3W@35237|dsDNA viruses no RNA stage,4QPGK@28883|Caudovirales,4QNW0@10744|Podoviridae 10744|Podoviridae S exonuclease activity - GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 - - - - - - - - - - - k59_26374_1 595537.Varpa_2007 1.28e-17 82.0 COG3728@1|root,COG3728@2|Bacteria,1R986@1224|Proteobacteria,2VVD5@28216|Betaproteobacteria,4AFX5@80864|Comamonadaceae 28216|Betaproteobacteria L PFAM Terminase small subunit - - - - - - - - - - - - Terminase_2 k59_167178_1 1262914.BN533_00198 1.41e-12 73.9 COG4695@1|root,COG4695@2|Bacteria,1TP8B@1239|Firmicutes 1239|Firmicutes OU Phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_59246_1 1215092.PA6_046_00270 8.86e-06 45.4 28QDM@1|root,2ZCVZ@2|Bacteria,1P5MR@1224|Proteobacteria,1SW6Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_59246_2 264730.PSPPH_2791 2.54e-94 291.0 2CI0W@1|root,2Z81W@2|Bacteria,1R9FZ@1224|Proteobacteria,1S0NA@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage X family - - - - - - - - - - - - Phage_CRI,Phage_X k59_142440_3 520999.PROVALCAL_01154 2.54e-26 115.0 COG0582@1|root,COG0582@2|Bacteria,1MVZB@1224|Proteobacteria,1RP4Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Belongs to the 'phage' integrase family - - - ko:K14059 - - - - ko00000 - - - Arm-DNA-bind_2,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase k59_258588_1 1502724.FF80_03325 3.88e-14 73.2 COG0593@1|root,COG0593@2|Bacteria,1P7AH@1224|Proteobacteria,2UXII@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Bacterial dnaA protein helix-turn-helix - - - - - - - - - - - - Bac_DnaA_C k59_167307_5 1147.D082_16180 8.61e-15 80.9 COG0582@1|root,COG0582@2|Bacteria,1GHVX@1117|Cyanobacteria,1H61F@1142|Synechocystis 1117|Cyanobacteria L Phage integrase, N-terminal SAM-like domain xerC - - ko:K03733 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase k59_17621_5 1385658.U5KPZ6_9VIRU 4.61e-146 437.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_183663_1 472759.Nhal_0999 2.82e-24 96.7 COG5471@1|root,COG5471@2|Bacteria,1NMSP@1224|Proteobacteria,1SHMP@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Uncharacterized conserved protein (DUF2190) - - - - - - - - - - - - DUF2190 k59_84139_1 1165094.RINTHH_3920 1.78e-72 231.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_84139_3 105154.Q9MBU6_9VIRU 1.54e-216 617.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_51194_1 145579.CAPSD_BPPHM 8.05e-121 369.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_118417_1 439496.RBY4I_316 3.9e-17 87.4 COG3598@1|root,COG4643@1|root,COG3598@2|Bacteria,COG4643@2|Bacteria,1R6M4@1224|Proteobacteria,2U1V0@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction - - - ko:K06919 - - - - ko00000 - - - PriCT_2,Prim-Pol k59_109699_1 1609634.A0A0C5AFV4_9VIRU 1.6e-38 143.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_159148_1 979556.MTES_0754 6.91e-22 92.4 COG4696@1|root,COG4696@2|Bacteria,2IIPK@201174|Actinobacteria 201174|Actinobacteria J Phosphoribosyl-ATP pyrophosphohydrolase - - - - - - - - - - - - Acetyltransf_3,PRA-PH k59_159148_5 1120936.KB907208_gene1107 7.74e-144 429.0 COG0209@1|root,COG0209@2|Bacteria,2IC1H@201174|Actinobacteria 201174|Actinobacteria F Ribonucleotide reductase, barrel domain - - - - - - - - - - - - Ribonuc_red_lgC k59_27113_1 1609634.A0A0C5AFV4_9VIRU 2.94e-62 215.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_159294_1 1123487.KB892865_gene1388 1.17e-26 113.0 COG3378@1|root,COG3378@2|Bacteria 2|Bacteria KL Phage plasmid primase P4 family - - - ko:K06919 - - - - ko00000 - - - PriCT_2,Prim-Pol k59_35197_2 1122217.KB899582_gene1559 0.000215 46.2 2CC4J@1|root,2Z7W8@2|Bacteria,1UX5W@1239|Firmicutes,4H2HV@909932|Negativicutes 909932|Negativicutes S Domain of unknown function (DUF932) - - - - - - - - - - - - DUF932 k59_10094_1 1073754.G0ZND4_9VIRU 1.63e-37 140.0 4QGM3@10239|Viruses 10239|Viruses S oxidoreductase activity - - - - - - - - - - - - - k59_68290_1 1609634.A0A0C5AFV4_9VIRU 4.24e-33 130.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_242404_3 994573.T472_0211805 1.9e-57 201.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,36M8D@31979|Clostridiaceae 186801|Clostridia L SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,SNF2_N k59_109878_1 666684.AfiDRAFT_1861 3.64e-26 113.0 28JTG@1|root,2Z9IR@2|Bacteria,1R0GC@1224|Proteobacteria,2TURR@28211|Alphaproteobacteria,3JUCC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF2793) - - - - - - - - - - - - DUF2793 k59_19196_1 1479239.JQMU01000001_gene2738 1.61e-20 94.4 COG4653@1|root,COG4653@2|Bacteria,1MWMB@1224|Proteobacteria,2TUJN@28211|Alphaproteobacteria,2K6TT@204457|Sphingomonadales 204457|Sphingomonadales S Phage capsid family - - - - - - - - - - - - Phage_capsid k59_119590_1 1500306.JQLA01000039_gene6535 5.96e-21 101.0 COG4733@1|root,COG4733@2|Bacteria,1Q2WW@1224|Proteobacteria,2TUS9@28211|Alphaproteobacteria,4B9ZW@82115|Rhizobiaceae 28211|Alphaproteobacteria S Phage-related protein, tail component - - - - - - - - - - - - DUF1983,Phage-tail_3 k59_53185_2 1123489.AUAN01000002_gene671 2.46e-06 55.8 COG3935@1|root,COG3935@2|Bacteria,1VHH7@1239|Firmicutes,4H5YT@909932|Negativicutes 909932|Negativicutes L DnaD domain protein - - - - - - - - - - - - - k59_185483_3 756275.H2BCQ3_9CAUD 3.36e-55 204.0 4QC8M@10239|Viruses,4QWMX@35237|dsDNA viruses no RNA stage,4QQU8@28883|Caudovirales,4QM0A@10699|Siphoviridae 10699|Siphoviridae S Protein of unknown function (DUF1073) - - - - - - - - - - - - - k59_11021_1 1234888.K0A2J2_9VIRU 2.51e-44 162.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_209955_1 160488.PP_2270 2.87e-123 373.0 COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1QWI1@1224|Proteobacteria,1RZ7K@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Toprim-like - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - AAA_25,DnaB_C,Toprim_2 k59_169389_1 105154.Q9MBU6_9VIRU 6.9e-110 343.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_202186_1 691965.D4P7L7_9CAUD 5.34e-47 171.0 4QB9J@10239|Viruses,4QXFE@35237|dsDNA viruses no RNA stage,4QS1Z@28883|Caudovirales,4QN8F@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_77904_12 260827.Q6R6A4_9CAUD 5.82e-07 52.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales 28883|Caudovirales S N-methyltransferase activity - - - - - - - - - - - - - k59_260491_1 1692256.A0A0K1RL85_9CIRC 2.37e-70 227.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_60748_1 768066.HELO_2115 1.01e-30 115.0 COG2197@1|root,COG2197@2|Bacteria,1NA3X@1224|Proteobacteria 1224|Proteobacteria KT HNH endonuclease - - - - - - - - - - - - HNH_3 k59_169391_1 1088868.CIN_22030 3.76e-39 138.0 2E80D@1|root,332EP@2|Bacteria,1NAIR@1224|Proteobacteria 1224|Proteobacteria S Protein involved in DNA replication and plasmid maintenance - - - - - - - - - - - - RepL k59_128025_1 1112209.AHVZ01000011_gene243 2e-68 215.0 COG1161@1|root,COG1161@2|Bacteria,1MV5H@1224|Proteobacteria,1RP79@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity rbgA - - ko:K14540 - - - - ko00000,ko03009 - - - MMR_HSR1 k59_128025_2 1055815.AYYA01000039_gene71 2.92e-32 119.0 COG0322@1|root,COG0322@2|Bacteria,1R5TC@1224|Proteobacteria,1S0PX@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Domain of unknown function (DUF4357) - - - - - - - - - - - - DUF4357 k59_227212_1 1609634.A0A0C5AFV4_9VIRU 5.81e-117 354.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_251406_1 768710.DesyoDRAFT_1133 7.92e-07 57.8 COG4675@1|root,COG5301@1|root,COG4675@2|Bacteria,COG5301@2|Bacteria,1UUY8@1239|Firmicutes,24TGK@186801|Clostridia 186801|Clostridia S tail collar domain protein - - - - - - - - - - - - - k59_54357_1 1564096.A0A0A0YT02_9CAUD 1.38e-111 339.0 4QC6N@10239|Viruses,4QPEG@28883|Caudovirales,4QI30@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_78849_2 333138.LQ50_04395 3.73e-72 244.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4H9YP@91061|Bacilli,1ZB0Z@1386|Bacillus 91061|Bacilli KL SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,SNF2_N k59_78849_7 1166018.FAES_1814 1.39e-21 92.0 COG3108@1|root,COG3108@2|Bacteria,4NW30@976|Bacteroidetes,47T29@768503|Cytophagia 976|Bacteroidetes S Peptidase M15 - - - - - - - - - - - - Peptidase_M15_3 k59_228299_2 1123256.KB907925_gene1522 1.61e-06 56.6 COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,1RN65@1236|Gammaproteobacteria,1X3IJ@135614|Xanthomonadales 135614|Xanthomonadales K Belongs to the ParB family parB - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_228299_3 305900.GV64_01840 5.01e-05 53.5 COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,1RMNP@1236|Gammaproteobacteria,1XI4U@135619|Oceanospirillales 135619|Oceanospirillales L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 k59_228299_10 1304872.JAGC01000009_gene896 2.83e-70 238.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,42M7X@68525|delta/epsilon subdivisions,2WJCA@28221|Deltaproteobacteria,2M7ZB@213115|Desulfovibrionales 28221|Deltaproteobacteria L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_37083_2 105154.Q9MBU6_9VIRU 1.31e-64 215.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_186689_2 1353531.AZNX01000042_gene4042 4.7e-39 149.0 COG5362@1|root,COG5362@2|Bacteria,1NKZK@1224|Proteobacteria,2U4BJ@28211|Alphaproteobacteria,4BMKJ@82115|Rhizobiaceae 28211|Alphaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_70685_1 742740.HMPREF9474_02271 2.52e-116 347.0 28J3N@1|root,2Z8ZU@2|Bacteria,1V15Z@1239|Firmicutes,249Z0@186801|Clostridia,221RR@1506553|Lachnoclostridium 186801|Clostridia S Phage portal protein - - - - - - - - - - - - Phage_portal k59_221111_1 40571.JOEA01000001_gene5423 4.83e-11 61.2 COG0756@1|root,COG0756@2|Bacteria,2IHYY@201174|Actinobacteria,4E2RG@85010|Pseudonocardiales 201174|Actinobacteria F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA dut GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase k59_244320_1 1100720.ALKN01000018_gene1736 1.51e-47 185.0 COG3598@1|root,COG3598@2|Bacteria,1R8YZ@1224|Proteobacteria 1224|Proteobacteria L Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction - - - - - - - - - - - - DUF3987,PriCT_2,Prim-Pol,RepB_primase k59_54449_1 1385658.U5KPZ6_9VIRU 3.49e-39 148.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_137349_1 1341151.ASZU01000008_gene1531 3.5e-25 115.0 COG1783@1|root,COG1783@2|Bacteria,1VK0H@1239|Firmicutes,4HQ2H@91061|Bacilli 91061|Bacilli S Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C k59_210997_3 1304885.AUEY01000151_gene646 1.26e-09 56.6 2EF8R@1|root,32W7B@2|Bacteria,1N6JW@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_235741_1 707757.D5JF64_9CAUD 2.93e-14 76.3 4QAJX@10239|Viruses,4QUZ8@35237|dsDNA viruses no RNA stage,4QPK4@28883|Caudovirales,4QHZF@10662|Myoviridae 10662|Myoviridae S Pfam:DUF5051 - - - - - - - - - - - - - k59_95074_2 1233950.IW22_01175 1.1e-26 107.0 COG0863@1|root,COG0863@2|Bacteria,4NQQ1@976|Bacteroidetes,1I957@117743|Flavobacteriia,3ZRIJ@59732|Chryseobacterium 976|Bacteroidetes L DNA methylase - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_154059_1 1385658.U5KPZ6_9VIRU 1.39e-115 353.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_154059_6 1609634.A0A0C5ANA6_9VIRU 5.37e-08 58.9 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_154059_7 105154.Q9MBU6_9VIRU 5.46e-65 215.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_221123_1 257310.BB2234 1.08e-09 65.9 COG0845@1|root,COG4733@1|root,COG0845@2|Bacteria,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria,2VJEP@28216|Betaproteobacteria,3T707@506|Alcaligenaceae 28216|Betaproteobacteria M to Bacteriophage D3 Orf26 orf26 SWALL Q9MC95 (EMBL AF165214) (909 aa) fasta scores E() 4.8e-23, 25.98 id in 689 aa - - - - - - - - - - - - DUF1983,Phage-tail_3 k59_235744_1 1165094.RINTHH_3920 6.12e-55 183.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_130793_3 145579.CAPSD_BPPHM 1.2e-235 665.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_114284_2 981383.AEWH01000018_gene3237 3.03e-19 85.1 COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,4HH8I@91061|Bacilli 91061|Bacilli L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_245395_1 575564.HMPREF0014_00741 1.16e-08 53.5 2D1MV@1|root,32TAZ@2|Bacteria,1N45A@1224|Proteobacteria,1S954@1236|Gammaproteobacteria,3NNB4@468|Moraxellaceae 1236|Gammaproteobacteria S Phage protein (N4 Gp49/phage Sf6 gene 66) family - - - - - - - - - - - - DUF2829,Phage_gp49_66 k59_80104_1 105154.Q9MBU6_9VIRU 2e-71 235.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_155490_1 279238.Saro_2987 3.65e-35 132.0 2CYA9@1|root,32T3V@2|Bacteria,1RGRN@1224|Proteobacteria,2U90D@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_229679_1 216594.MMAR_3451 1.43e-24 105.0 COG1409@1|root,COG1409@2|Bacteria,2GRKX@201174|Actinobacteria,236UU@1762|Mycobacteriaceae 201174|Actinobacteria S Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - - - - - - - - - - Metallophos,Metallophos_2 k59_38316_2 1121456.ATVA01000015_gene2512 1.69e-05 52.4 2C9JF@1|root,32RPD@2|Bacteria,1N8CG@1224|Proteobacteria,42REW@68525|delta/epsilon subdivisions,2WNQ1@28221|Deltaproteobacteria,2MB30@213115|Desulfovibrionales 28221|Deltaproteobacteria S ERF superfamily - - - - - - - - - - - - ERF k59_122439_1 999425.HMPREF9186_02011 3.19e-07 52.4 2EI4V@1|root,33BW7@2|Bacteria,1VKQH@1239|Firmicutes,4HRPN@91061|Bacilli 91061|Bacilli S Protein of unknwon function (DUF3310) - - - - - - - - - - - - DUF3310 k59_96216_1 1385658.U5KNR1_9VIRU 1.14e-73 236.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_96216_3 1385658.U5KPZ6_9VIRU 2.27e-87 276.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_188548_1 1327036.R4JHP8_9CAUD 3.02e-10 65.1 4QCEF@10239|Viruses,4QVWZ@35237|dsDNA viruses no RNA stage,4QTBA@28883|Caudovirales,4QMGR@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_205053_1 1298608.JCM18900_16 1.11e-41 142.0 2EHU8@1|root,33BJW@2|Bacteria,1NIG4@1224|Proteobacteria,1SJ06@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_162959_2 314265.R2601_22976 7.68e-12 63.2 2ESDP@1|root,33JYD@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_13400_3 105154.Q9MBU3_9VIRU 1.45e-11 68.2 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_13400_4 1986029.Q9MBM6_9VIRU 9.48e-26 102.0 4QDBB@10239|Viruses,4QUM0@29258|ssDNA viruses,4QP4D@10841|Microviridae 10841|Microviridae S Chlamydia-phage Chp2 scaffold (Chlamy_scaf) - - - - - - - - - - - - - k59_147839_1 864702.OsccyDRAFT_0687 3.06e-47 160.0 2CWXD@1|root,32T0J@2|Bacteria,1GAQJ@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - k59_33554_3 1346791.M529_03760 1.43e-17 90.5 COG0358@1|root,COG0358@2|Bacteria,1N3K5@1224|Proteobacteria,2UDNI@28211|Alphaproteobacteria,2K52G@204457|Sphingomonadales 204457|Sphingomonadales L CHC2 zinc finger - - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - Toprim_3,zf-CHC2 k59_207638_1 1150626.PHAMO_340052 6.18e-06 50.8 2CK39@1|root,32SBG@2|Bacteria,1Q39J@1224|Proteobacteria,2VA7Q@28211|Alphaproteobacteria,2JX2Y@204441|Rhodospirillales 204441|Rhodospirillales S Phage gp6-like head-tail connector protein - - - - - - - - - - - - Phage_connect_1 k59_249165_6 113395.AXAI01000002_gene5437 5.11e-51 179.0 28PTM@1|root,2ZCEU@2|Bacteria,1R5DD@1224|Proteobacteria,2TVG7@28211|Alphaproteobacteria,3JU4C@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Family of unknown function (DUF5309) - - - - - - - - - - - - DUF5309 k59_240808_1 546264.NEIFLAOT_01708 6.37e-18 84.7 2D784@1|root,32TNH@2|Bacteria,1N098@1224|Proteobacteria,2VX0M@28216|Betaproteobacteria,2KTG2@206351|Neisseriales 206351|Neisseriales - - - - - - - - - - - - - - - k59_257453_1 368408.Tpen_1388 1.64e-25 109.0 COG1404@1|root,arCOG00702@2157|Archaea,2XPS2@28889|Crenarchaeota 28889|Crenarchaeota O Belongs to the peptidase S8 family - - - - - - - - - - - - Peptidase_S8 k59_224180_1 1123487.KB892865_gene1375 2.54e-89 275.0 28MVD@1|root,2ZB2Y@2|Bacteria,1R8NK@1224|Proteobacteria,2VPRP@28216|Betaproteobacteria,2KZJK@206389|Rhodocyclales 206389|Rhodocyclales S Protein of unknown function (DUF4043) - - - - - - - - - - - - DUF4043 k59_174277_3 1196835.A458_20925 9.28e-22 100.0 COG3179@1|root,COG3179@2|Bacteria,1R0IJ@1224|Proteobacteria,1T4IM@1236|Gammaproteobacteria,1Z1I3@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria M LysM domain - - - - - - - - - - - - - k59_174277_5 1429767.W6B150_9CAUD 2.37e-302 851.0 4QF3C@10239|Viruses,4QWIA@35237|dsDNA viruses no RNA stage,4QU4U@28883|Caudovirales,4QNNQ@10744|Podoviridae 10744|Podoviridae S host cell wall - - - - - - - - - - - - - k59_8664_1 935261.JAGL01000009_gene1168 2.24e-79 244.0 COG1351@1|root,COG1351@2|Bacteria,1MWY8@1224|Proteobacteria,2TTER@28211|Alphaproteobacteria,43QDX@69277|Phyllobacteriaceae 28211|Alphaproteobacteria F Thymidylate synthase complementing protein thyX - 2.1.1.148 ko:K03465 ko00240,ko00670,ko01100,map00240,map00670,map01100 - R06613 RC00022,RC00332 ko00000,ko00001,ko01000 - - - Thy1 k59_224183_1 220341.16506038 1.33e-05 52.8 COG0419@1|root,COG3941@1|root,COG0419@2|Bacteria,COG3941@2|Bacteria,1MZWI@1224|Proteobacteria,1RQ7Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Mu-like prophage protein - - - - - - - - - - - - - k59_116552_1 948071.S4S2F8_9CAUD 3.72e-20 94.0 4QGCH@10239|Viruses,4QYIQ@35237|dsDNA viruses no RNA stage,4QU4V@28883|Caudovirales,4QNJ3@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_124920_4 469381.Dpep_0394 3.39e-27 107.0 COG0817@1|root,COG0817@2|Bacteria,3TCBE@508458|Synergistetes 508458|Synergistetes L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group - - - - - - - - - - - - - k59_216097_1 1385658.U5KQQ9_9VIRU 0.000651 46.6 4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_1280_1 1416009.V9VG44_9CAUD 1.67e-22 97.8 4QH9N@10239|Viruses,4QX7K@35237|dsDNA viruses no RNA stage,4QUDB@28883|Caudovirales,4QNJY@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_225006_2 1385658.U5KNR1_9VIRU 7.1e-11 63.2 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_158460_1 1175654.A0A0S0N897_9CAUD 2.97e-23 99.8 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QM52@10699|Siphoviridae 10699|Siphoviridae S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor - - - - - - - - - - - - - k59_34349_2 1192868.CAIU01000008_gene967 1.15e-63 201.0 COG1738@1|root,COG1738@2|Bacteria,1RDSF@1224|Proteobacteria 1224|Proteobacteria S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage - - - ko:K09125 - - - - ko00000 - - - Vut_1 k59_34349_3 1229485.AMYV01000092_gene800 2.34e-29 113.0 28J67@1|root,2Z91Y@2|Bacteria,1R7RG@1224|Proteobacteria,1RZB8@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_125569_1 631362.Thi970DRAFT_04661 0.000921 43.1 COG0210@1|root,COG0514@1|root,COG0210@2|Bacteria,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,1RMPG@1236|Gammaproteobacteria,1WX8Y@135613|Chromatiales 135613|Chromatiales L DNA helicase - - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,UvrD-helicase,UvrD_C k59_142151_2 1692244.A0A0K1RLR5_9CIRC 1.85e-84 261.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_175037_6 105154.Q9MBU0_9VIRU 2.54e-27 115.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_59168_2 1618248.A0A0C5IB82_9CIRC 5.72e-12 72.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_83994_1 913183.E5RUZ8_9CAUD 1.19e-77 264.0 4QBMV@10239|Viruses,4QUU6@35237|dsDNA viruses no RNA stage,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_208293_1 438753.AZC_0840 8.07e-46 167.0 COG3170@1|root,COG3170@2|Bacteria,1R69E@1224|Proteobacteria,2U3B9@28211|Alphaproteobacteria 28211|Alphaproteobacteria NU Phage P22-like portal protein - - - - - - - - - - - - - k59_34470_2 991.IW20_14795 1.47e-25 120.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,1HXMT@117743|Flavobacteriia,2NSJE@237|Flavobacterium 976|Bacteroidetes L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_100688_1 1536592.A0A088F773_9VIRU 4.08e-24 103.0 4QB5I@10239|Viruses 10239|Viruses S N-methyltransferase activity - - - - - - - - - - - - - k59_100688_2 487316.BBNM01000015_gene2010 1.68e-41 152.0 COG0338@1|root,COG0338@2|Bacteria,1P85S@1224|Proteobacteria,1RMNW@1236|Gammaproteobacteria,3NMFI@468|Moraxellaceae 1236|Gammaproteobacteria L D12 class N6 adenine-specific DNA methyltransferase - - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 k59_249880_1 1609634.A0A0C5AFV4_9VIRU 7.27e-103 319.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_75914_1 644107.SL1157_2511 9.54e-05 49.7 COG3391@1|root,COG3391@2|Bacteria,1MXN7@1224|Proteobacteria,2TR83@28211|Alphaproteobacteria,4NAE9@97050|Ruegeria 28211|Alphaproteobacteria S GTA TIM-barrel-like domain - - - - - - - - - - - - GTA_TIM,Phage-tail_3 k59_100691_1 1168478.I6R9L9_9CAUD 1.01e-40 156.0 4QCHV@10239|Viruses,4QUW9@35237|dsDNA viruses no RNA stage,4QQEZ@28883|Caudovirales,4QMEA@10699|Siphoviridae 10699|Siphoviridae S Virulence-associated protein E - - - - - - - - - - - - - k59_226258_3 1226994.AMZB01000121_gene3504 1.98e-59 208.0 COG1793@1|root,COG1793@2|Bacteria,1NP4A@1224|Proteobacteria,1STVK@1236|Gammaproteobacteria 1236|Gammaproteobacteria L ATP dependent DNA ligase domain - - 6.5.1.1,6.5.1.6,6.5.1.7 ko:K10747 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00381,R00382,R10822,R10823 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - DNA_ligase_A_M k59_226258_6 1211280.J7I192_9CAUD 6e-32 122.0 4QFW8@10239|Viruses,4R060@35237|dsDNA viruses no RNA stage,4QRFQ@28883|Caudovirales,4QHVW@10662|Myoviridae 10662|Myoviridae S hydrolase activity - - - - - - - - - - - - - k59_226258_7 1287476.HMPREF1651_03450 5.8e-37 134.0 COG2131@1|root,COG2131@2|Bacteria,4NM48@976|Bacteroidetes,2FRZ1@200643|Bacteroidia 976|Bacteroidetes F Cytidine and deoxycytidylate deaminase zinc-binding region comEB - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 k59_226258_8 342610.Patl_3377 3.43e-07 53.1 COG0720@1|root,COG0720@2|Bacteria,1MXVT@1224|Proteobacteria,1RN6H@1236|Gammaproteobacteria,2PZKR@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria H COG0720 6-pyruvoyl-tetrahydropterin synthase SO2179 - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - PTPS k59_35354_1 145579.CAPSD_BPPHM 3.21e-84 265.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_176130_2 1498011.A0A096XUT2_9CAUD 1.14e-06 49.3 4QAK6@10239|Viruses,4QRSI@28883|Caudovirales,4QNEJ@10744|Podoviridae 10744|Podoviridae S Pfam:DUF5309 - - - - - - - - - - - - - k59_84681_4 1415779.JOMH01000001_gene2347 3.11e-09 60.5 COG0464@1|root,COG0464@2|Bacteria,1QU82@1224|Proteobacteria,1SA9J@1236|Gammaproteobacteria,1XDA8@135614|Xanthomonadales 135614|Xanthomonadales O Zonular occludens toxin (Zot) - - - - - - - - - - - - Zot k59_43677_1 1788444.A0A190WHA5_9CIRC 1.05e-21 100.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_68471_1 889338.G3BM03_9CAUD 3.06e-51 182.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QI6A@10662|Myoviridae 10662|Myoviridae S Ribonucleotide reductase, barrel domain - - - - - - - - - - - - - k59_259557_2 1278073.MYSTI_04932 2.48e-13 68.9 COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,42SP5@68525|delta/epsilon subdivisions,2WP39@28221|Deltaproteobacteria,2YUQU@29|Myxococcales 28221|Deltaproteobacteria K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair lexA GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 k59_135170_1 1235802.C823_01030 9.54e-19 88.2 COG0338@1|root,COG0338@2|Bacteria,1UBIY@1239|Firmicutes,24D2Y@186801|Clostridia,25WS6@186806|Eubacteriaceae 186801|Clostridia L D12 class N6 adenine-specific DNA methyltransferase - - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 k59_119009_1 1432056.X781_9480 1.45e-134 389.0 COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,1RYB9@1236|Gammaproteobacteria,1Y81V@135625|Pasteurellales 135625|Pasteurellales EGP Tetracycline resistance protein, class E of root UniRef RepID TCR5_ECOLX - - - ko:K08151 - M00668 - - ko00000,ko00002,ko01504,ko02000 2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75 - - MFS_1 k59_159620_1 979533.F1D0V0_9CAUD 6.11e-51 180.0 4QCM5@10239|Viruses,4QVZY@35237|dsDNA viruses no RNA stage,4QQFH@28883|Caudovirales,4QNDH@10744|Podoviridae 10744|Podoviridae S Bacteriophage head to tail connecting protein - GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019028,GO:0019058,GO:0019068,GO:0019072,GO:0019073,GO:0032991,GO:0044403,GO:0044419,GO:0044423,GO:0046798,GO:0051704 - - - - - - - - - - - k59_151902_1 1379715.S5TMW6_9CIRC 1.12e-25 105.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_101869_2 459349.CLOAM0317 2.08e-09 57.8 COG0789@1|root,COG0789@2|Bacteria,2NQ3P@2323|unclassified Bacteria 2|Bacteria K helix_turn_helix, mercury resistance ycgE - - ko:K19591,ko:K22491 - M00769 - - ko00000,ko00002,ko01504,ko03000 - - - MerR_1 k59_101869_4 1274524.BSONL12_06063 2.26e-93 301.0 COG5545@1|root,COG5545@2|Bacteria,1TQNX@1239|Firmicutes,4HCHZ@91061|Bacilli,1ZDD8@1386|Bacillus 91061|Bacilli L Virulence-associated protein E - - - - - - - - - - - - VirE k59_251630_1 1429767.W6ASK5_9CAUD 5.82e-87 272.0 4QBMV@10239|Viruses,4QUU6@35237|dsDNA viruses no RNA stage,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_202436_1 1609634.A0A0C5AFV4_9VIRU 5.29e-100 311.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_177494_1 1218084.BBJK01000077_gene5333 1.99e-104 317.0 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,2VP7E@28216|Betaproteobacteria,1KFK1@119060|Burkholderiaceae 28216|Betaproteobacteria S Phage portal protein - - - - - - - - - - - - Phage_portal k59_78279_2 1123058.KB894217_gene638 4.79e-57 191.0 2CK0Y@1|root,2ZBCW@2|Bacteria,4NM1K@976|Bacteroidetes,1II9Z@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_102968_1 391595.RLO149_c014800 6.71e-05 47.8 2EJIR@1|root,33D9N@2|Bacteria,1NHKK@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - DUF4376,Phage_tail_APC k59_169796_1 1348338.ADILRU_1485 1.02e-07 53.5 2BZ0T@1|root,32R45@2|Bacteria,2IK63@201174|Actinobacteria,4FSYX@85023|Microbacteriaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_202640_1 1397528.Q671_08010 2.12e-09 63.2 COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,1QZAD@1224|Proteobacteria,1RYP3@1236|Gammaproteobacteria,1XMG9@135619|Oceanospirillales 135619|Oceanospirillales D nuclear chromosome segregation - - - - - - - - - - - - - k59_251810_1 1385658.U5KPZ6_9VIRU 1.64e-79 256.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_193781_1 679201.HMPREF9334_00465 6.78e-15 71.6 2E3FM@1|root,32YEF@2|Bacteria 2|Bacteria S VRR-NUC domain - - - - - - - - - - - - VRR_NUC k59_193781_2 753084.F4YCI6_9CAUD 2.98e-36 130.0 4QAIJ@10239|Viruses,4QVZ9@35237|dsDNA viruses no RNA stage,4QPXI@28883|Caudovirales,4QM02@10699|Siphoviridae 10699|Siphoviridae S C-5 cytosine-specific DNA methylase - - - - - - - - - - - - - k59_202644_1 742817.HMPREF9449_01796 2.24e-53 177.0 COG1032@1|root,COG1032@2|Bacteria 2|Bacteria C radical SAM domain protein - - - - - - - - - - - - B12-binding,Radical_SAM k59_36425_3 753084.F4YCI4_9CAUD 2.45e-74 238.0 4QAIK@10239|Viruses,4QUPH@35237|dsDNA viruses no RNA stage,4QS4V@28883|Caudovirales,4QKNC@10699|Siphoviridae 10699|Siphoviridae S hydrolase activity - - - - - - - - - - - - - k59_177662_1 1385658.U5KNR1_9VIRU 1.44e-42 152.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_28881_2 1041147.AUFB01000014_gene329 1.64e-21 93.6 2CXZV@1|root,32T32@2|Bacteria,1N4R9@1224|Proteobacteria,2UM96@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_210345_1 1986029.Q9MBM3_9VIRU 3.53e-37 138.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_251821_1 1609634.A0A0C5ANA6_9VIRU 6.39e-23 99.0 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_4294_1 1379281.AVAG01000008_gene1401 9.52e-09 63.5 COG0621@1|root,COG3551@1|root,COG0621@2|Bacteria,COG3551@2|Bacteria,1RB2G@1224|Proteobacteria,42UMV@68525|delta/epsilon subdivisions,2WR43@28221|Deltaproteobacteria,2MDHR@213115|Desulfovibrionales 28221|Deltaproteobacteria J Sulfotransferase family - - - - - - - - - - - - - k59_262265_1 626887.J057_01640 3.5e-30 133.0 2DBPZ@1|root,2ZABJ@2|Bacteria,1R7CU@1224|Proteobacteria,1SKX7@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_79518_1 1231190.NA8A_23409 4.51e-28 110.0 COG4122@1|root,COG4122@2|Bacteria,1QWQR@1224|Proteobacteria,2TX2B@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Methyltransferase domain - - - - - - - - - - - - Methyltransf_24 k59_179154_2 1007105.PT7_P040 3.5e-07 55.1 COG4723@1|root,COG4733@1|root,COG4723@2|Bacteria,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria,2VJEP@28216|Betaproteobacteria,3T592@506|Alcaligenaceae 28216|Betaproteobacteria S Putative phage tail protein - - - - - - - - - - - - DUF1983,Phage-tail_3 k59_204287_1 1401297.U3PDJ9_9CAUD 4.81e-45 155.0 4QARC@10239|Viruses,4QV4E@35237|dsDNA viruses no RNA stage,4QPDS@28883|Caudovirales,4QP0H@10744|Podoviridae 10744|Podoviridae S nucleic acid binding - - - - - - - - - - - - - k59_37705_1 1618257.A0A0C5IBI9_9CIRC 5.47e-69 219.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_12933_1 691965.D4P7B9_9CAUD 7.67e-15 70.5 4QFDH@10239|Viruses,4QWV5@35237|dsDNA viruses no RNA stage,4QPB8@28883|Caudovirales,4QKNN@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_104333_1 326424.FRAAL6246 3.58e-10 66.2 COG4124@1|root,COG4124@2|Bacteria,2GN8K@201174|Actinobacteria 201174|Actinobacteria G Belongs to the glycosyl hydrolase 26 family - - - - - - - - - - - - Glyco_hydro_26 k59_30411_1 1204539.J9QGS0_9CAUD 1.51e-05 53.5 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QKNE@10699|Siphoviridae 10699|Siphoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_244815_2 1150474.JQJI01000017_gene584 1.02e-07 56.6 COG0216@1|root,COG0216@2|Bacteria,2GCGU@200918|Thermotogae 200918|Thermotogae J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA - - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 k59_113505_2 118168.MC7420_6803 2.12e-07 64.7 COG2706@1|root,COG2931@1|root,COG3391@1|root,COG2706@2|Bacteria,COG2931@2|Bacteria,COG3391@2|Bacteria,1G0EB@1117|Cyanobacteria,1H803@1150|Oscillatoriales 1117|Cyanobacteria G PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP - - - ko:K20276 ko02024,map02024 - - - ko00000,ko00001 - - - Calx-beta,DUF4347,He_PIG,HemolysinCabind,PPC,TIG,VCBS k59_79529_1 348824.LPU83_0595 2.48e-48 172.0 COG3740@1|root,COG3740@2|Bacteria,1QVIJ@1224|Proteobacteria,2TVIM@28211|Alphaproteobacteria,4BNVZ@82115|Rhizobiaceae 28211|Alphaproteobacteria S Phage capsid family - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_104339_1 1458462.JNLK01000001_gene1564 4.19e-17 90.9 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,2487V@186801|Clostridia,27JEU@186928|unclassified Lachnospiraceae 186801|Clostridia L DNA polymerase A domain - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_154926_1 665956.HMPREF1032_00686 7.12e-21 103.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia,3WN92@541000|Ruminococcaceae 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_237292_2 1692250.A0A0K1RLR1_9CIRC 2.37e-63 207.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_72664_4 1429767.W6ARH7_9CAUD 8.08e-53 183.0 4QAR1@10239|Viruses,4QUNA@35237|dsDNA viruses no RNA stage,4QPJE@28883|Caudovirales,4QNDS@10744|Podoviridae 10744|Podoviridae S ATPase activity - - - - - - - - - - - - - k59_131208_1 76869.PputGB1_3455 2.95e-13 74.7 2C2XN@1|root,32GT6@2|Bacteria,1REZE@1224|Proteobacteria,1SG9Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria S ERF superfamily - - - - - - - - - - - - ERF k59_230107_1 1788444.A0A190WHB9_9CIRC 9.13e-48 168.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_7249_2 411460.RUMTOR_02024 0.000135 45.4 2A0KC@1|root,30NQJ@2|Bacteria,1V3K4@1239|Firmicutes,24HYK@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_48331_1 59538.XP_005976423.1 7.13e-51 176.0 COG0629@1|root,COG1252@1|root,KOG1653@2759|Eukaryota,KOG2495@2759|Eukaryota,3A4A4@33154|Opisthokonta,3BPVJ@33208|Metazoa,3D6VW@33213|Bilateria 33208|Metazoa L single-stranded DNA binding - - - - - - - - - - - - SSB k59_245820_2 1336237.JAEE01000001_gene2079 2.73e-08 62.0 2DKWM@1|root,30MCA@2|Bacteria,1RE79@1224|Proteobacteria,1S4D4@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - Phage_fiber_2 k59_114793_2 339671.Asuc_0051 2.81e-08 52.0 COG1551@1|root,COG1551@2|Bacteria,1N6PG@1224|Proteobacteria,1SCB4@1236|Gammaproteobacteria,1Y989@135625|Pasteurellales 135625|Pasteurellales J Could accelerate the degradation of some genes transcripts potentially through selective RNA binding csrA - - ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 - - - ko00000,ko00001,ko03019 - - - CsrA k59_14023_1 471881.PROPEN_03922 0.000886 47.0 COG5283@1|root,COG5412@1|root,COG5283@2|Bacteria,COG5412@2|Bacteria,1NFKU@1224|Proteobacteria,1RP2D@1236|Gammaproteobacteria,3Z3A4@583|Proteus 1236|Gammaproteobacteria S Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_114959_1 445692.E3SP60_9CAUD 1.7e-16 82.0 4QCM5@10239|Viruses,4QVZY@35237|dsDNA viruses no RNA stage,4QQFH@28883|Caudovirales,4QNDH@10744|Podoviridae 10744|Podoviridae S Bacteriophage head to tail connecting protein - GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019028,GO:0019058,GO:0019068,GO:0019072,GO:0019073,GO:0032991,GO:0044403,GO:0044419,GO:0044423,GO:0046798,GO:0051704 - - - - - - - - - - - k59_263590_2 1498011.A0A096XUU5_9CAUD 2.02e-77 245.0 4QAUT@10239|Viruses,4QQ7X@28883|Caudovirales,4QNET@10744|Podoviridae 10744|Podoviridae S DNA ligase (ATP) activity - - - - - - - - - - - - - k59_38919_1 913865.DOT_1568 6.35e-14 71.2 28MC2@1|root,2ZAQD@2|Bacteria,1VSEU@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - k59_80666_1 1476888.X4YGV5_9CAUD 2.91e-09 65.1 4QF5E@10239|Viruses,4R01K@35237|dsDNA viruses no RNA stage,4QS4R@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_72872_3 399739.Pmen_3960 3.16e-08 62.8 2EBVZ@1|root,335VC@2|Bacteria,1RHVC@1224|Proteobacteria,1SND1@1236|Gammaproteobacteria,1YD8D@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_156138_1 1618258.A0A0C5I9K3_9CIRC 3.47e-23 103.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_32852_3 342113.DM82_4346 8.66e-10 58.5 COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria 2|Bacteria L DNA primase activity - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - AAA_25,DnaB_C,Toprim_2,Toprim_4 k59_88456_8 796620.VIBC2010_19925 9.44e-29 121.0 COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,1RN7C@1236|Gammaproteobacteria,1XW4M@135623|Vibrionales 135623|Vibrionales S AAA domain (dynein-related subfamily) cobS - 6.6.1.2 ko:K09882 ko00860,ko01100,map00860,map01100 - R05227 RC02000 ko00000,ko00001,ko01000 - - - AAA_5,CbbQ_C,CobS_N k59_88456_9 684719.HIMB114_00009450 1.11e-07 61.2 COG4547@1|root,COG4547@2|Bacteria,1MX11@1224|Proteobacteria,2TS4N@28211|Alphaproteobacteria,4BPRN@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria H Cobalamin biosynthesis protein CobT cobT - 6.6.1.2 ko:K09883 ko00860,ko01100,map00860,map01100 - R05227 RC02000 ko00000,ko00001,ko01000 - - - CobT,CobT_C k59_64142_1 1123024.AUII01000006_gene4578 2.09e-32 127.0 COG4553@1|root,COG4553@2|Bacteria,2IDSN@201174|Actinobacteria,4E8YW@85010|Pseudonocardiales 201174|Actinobacteria I Protein of unknown function (DUF3141) - - - - - - - - - - - - DUF3141 k59_132111_1 1234888.K0A2J2_9VIRU 1.76e-48 171.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_255188_1 1618248.A0A0C5IB82_9CIRC 1.79e-21 95.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_156825_1 1280944.HY17_04705 4.12e-11 68.6 2E8SI@1|root,3333B@2|Bacteria,1N7MG@1224|Proteobacteria,2UJSF@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_255190_1 1437448.AZRT01000050_gene161 6.07e-33 130.0 COG0863@1|root,COG0863@2|Bacteria,1PCSC@1224|Proteobacteria,2U4M6@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_197268_1 1618247.A0A0C5IMK7_9CIRC 5.07e-07 56.6 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_140546_3 462590.A9J524_BPPYU 2.04e-30 119.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QKNE@10699|Siphoviridae 10699|Siphoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_206594_1 1293047.CBMA010000017_gene1018 2.38e-18 93.2 COG0210@1|root,arCOG00797@2157|Archaea,2XUH7@28890|Euryarchaeota,23S3W@183963|Halobacteria 183963|Halobacteria L COG0210 Superfamily I DNA and RNA helicases uvrD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k59_49683_1 488538.SAR116_0376 2.58e-119 369.0 COG3064@1|root,COG3064@2|Bacteria,1R6JV@1224|Proteobacteria,2U5NE@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Membrane - - - - - - - - - - - - - k59_197270_2 220341.16502724 1.07e-14 82.4 COG3948@1|root,COG3948@2|Bacteria,1MUFF@1224|Proteobacteria,1RNBJ@1236|Gammaproteobacteria,3ZMG0@590|Salmonella 1236|Gammaproteobacteria S Baseplate J-like protein J - - - - - - - - - - - Baseplate_J k59_264534_1 1609634.A0A0C5AFV4_9VIRU 9.46e-112 345.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_115874_1 1609634.A0A0C5AFV4_9VIRU 9.59e-18 88.2 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_23070_4 1268240.ATFI01000002_gene4881 3.76e-09 68.9 COG5545@1|root,COG5545@2|Bacteria,4NG2W@976|Bacteroidetes,2FNU1@200643|Bacteroidia,4AK96@815|Bacteroidaceae 976|Bacteroidetes S P-loop ATPase and inactivated derivatives - - - - - - - - - - - - DUF3874,VirE,VirE_N k59_23070_5 411471.SUBVAR_06729 1.52e-10 65.9 COG1475@1|root,COG1475@2|Bacteria,1V2SD@1239|Firmicutes,24GNZ@186801|Clostridia,3WJEB@541000|Ruminococcaceae 186801|Clostridia K Psort location Cytoplasmic, score 8.96 - - - - - - - - - - - - - k59_32999_1 1316932.MHH_c17930 4.41e-40 153.0 COG3567@1|root,COG3567@2|Bacteria,1R45U@1224|Proteobacteria,1RY7G@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF1073) - - - ko:K09961 - - - - ko00000 - - - DUF1073 k59_181429_2 306264.CUP0965 5.71e-24 103.0 COG0582@1|root,COG0582@2|Bacteria,1MVZB@1224|Proteobacteria,42M9T@68525|delta/epsilon subdivisions,2YNP9@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria L Belongs to the 'phage' integrase family - - - ko:K14059 - - - - ko00000 - - - Arm-DNA-bind_2,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase k59_116079_2 287.DR97_6347 4.17e-11 62.0 2AS3I@1|root,31HG7@2|Bacteria,1QF71@1224|Proteobacteria,1TCAD@1236|Gammaproteobacteria,1YK4E@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_165885_3 598467.BrE312_2702 2.53e-22 96.3 28RDB@1|root,2ZDSP@2|Bacteria,1RBF9@1224|Proteobacteria,1RQ0W@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - Tube k59_165885_24 1403946.Q615_SPAC00127G0154 4.64e-37 141.0 28HHC@1|root,2Z7T2@2|Bacteria,1TR3B@1239|Firmicutes 1239|Firmicutes S AAA domain - - - - - - - - - - - - AAA_24 k59_165885_27 1178540.BA70_16410 6.64e-15 87.4 COG3378@1|root,COG4983@1|root,COG3378@2|Bacteria,COG4983@2|Bacteria,1TQP9@1239|Firmicutes,4HBTB@91061|Bacilli,1ZEU3@1386|Bacillus 91061|Bacilli S D5 N terminal like - - - ko:K06919 - - - - ko00000 - - - D5_N,Pox_D5,PriCT_1,Prim-Pol k59_165885_28 4577.GRMZM2G428964_P01 0.000162 48.9 28IQY@1|root,2QR28@2759|Eukaryota,37QGJ@33090|Viridiplantae,3GH0X@35493|Streptophyta,3KT1A@4447|Liliopsida,3I7QK@38820|Poales 35493|Streptophyta - - - - - - - - - - - - - - - k59_165885_29 391600.ABRU01000057_gene378 8.74e-20 89.7 COG5018@1|root,COG5018@2|Bacteria,1QVMV@1224|Proteobacteria 1224|Proteobacteria L 3' exoribonuclease, RNase T-like - - - - - - - - - - - - DUF5051 k59_132770_2 1234888.K0A2J2_9VIRU 3.38e-130 393.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_116299_2 338963.Pcar_0521 2.48e-32 129.0 COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,42QJ2@68525|delta/epsilon subdivisions,2WM78@28221|Deltaproteobacteria,43VD6@69541|Desulfuromonadales 28221|Deltaproteobacteria S Putative metallopeptidase domain - - - - - - - - - - - - DUF2201,DUF2201_N k59_199157_1 113395.AXAI01000002_gene5437 1.7e-31 120.0 28PTM@1|root,2ZCEU@2|Bacteria,1R5DD@1224|Proteobacteria,2TVG7@28211|Alphaproteobacteria,3JU4C@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Family of unknown function (DUF5309) - - - - - - - - - - - - DUF5309 k59_41619_1 1986029.Q9MBM3_9VIRU 5.73e-10 62.8 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_41619_3 1385658.U5KPZ6_9VIRU 3.02e-149 440.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_207482_1 1234888.K0A2J2_9VIRU 1.82e-75 243.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_58183_3 856793.MICA_2369 9.15e-07 60.8 COG2911@1|root,COG5295@1|root,COG2911@2|Bacteria,COG5295@2|Bacteria,1NDSM@1224|Proteobacteria,2UK7X@28211|Alphaproteobacteria,4BT5Y@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria UW Chaperone of endosialidase - - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - Peptidase_S74 k59_58183_6 716928.AJQT01000109_gene1217 1.48e-47 157.0 2FEUE@1|root,346TC@2|Bacteria,1MZPB@1224|Proteobacteria,2UC4Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_224019_2 1121324.CLIT_24c01090 9.97e-51 194.0 COG0209@1|root,COG0209@2|Bacteria,1TT3U@1239|Firmicutes,24C4U@186801|Clostridia 186801|Clostridia F TIGRFAM ribonucleoside-triphosphate reductase, adenosylcobalamin-dependent - - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,Ribonuc_red_lgC k59_92149_4 105154.Q9MBU3_9VIRU 3.2e-12 70.9 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_92149_5 105154.Q9MBU6_9VIRU 1e-202 582.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_25990_2 1692250.A0A0K1RLR1_9CIRC 6.56e-30 118.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_100446_3 558152.IQ37_15185 3.62e-05 45.4 COG3108@1|root,COG3108@2|Bacteria,4NR15@976|Bacteroidetes,1I2YD@117743|Flavobacteriia 976|Bacteroidetes S D-alanyl-D-alanine carboxypeptidase - - - ko:K17733 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M15_4 k59_216789_2 1609634.A0A0C5AFT2_9VIRU 2.14e-05 48.9 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_166894_1 691965.D4P7D3_9CAUD 7.97e-35 135.0 4QAYV@10239|Viruses,4QUZ7@35237|dsDNA viruses no RNA stage,4QPU3@28883|Caudovirales,4QKKX@10699|Siphoviridae 10699|Siphoviridae S Phage portal protein - - - - - - - - - - - - - k59_166894_3 1122614.JHZF01000011_gene1718 1.37e-15 74.7 2C7JB@1|root,2ZXVG@2|Bacteria,1P7GB@1224|Proteobacteria,2UYPK@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_17320_2 105154.Q9MBU0_9VIRU 6.28e-26 112.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_25998_1 1453501.JELR01000001_gene2559 3.29e-55 181.0 COG0582@1|root,COG0582@2|Bacteria,1QB64@1224|Proteobacteria,1RY8S@1236|Gammaproteobacteria,468CF@72275|Alteromonadaceae 1236|Gammaproteobacteria L Phage integrase family - - - - - - - - - - - - Arm-DNA-bind_1,Phage_int_SAM_4,Phage_integrase k59_58980_3 2003327.CAPSD_BPCHP 6.28e-20 89.7 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_224912_2 318586.Pden_3765 2.28e-37 128.0 2D1MV@1|root,32TAZ@2|Bacteria,1N45A@1224|Proteobacteria,2UEJT@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Phage protein (N4 Gp49/phage Sf6 gene 66) family - - - - - - - - - - - - Phage_gp49_66 k59_224912_3 573413.Spirs_2785 2.6e-26 102.0 2AJ1X@1|root,319K5@2|Bacteria 2|Bacteria S Protein of unknown function (DUF2829) - - - - - - - - - - - - DUF2829 k59_150337_1 2003327.CAPSD_BPCHP 3.35e-31 129.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_233097_1 1385658.U5KPZ6_9VIRU 7.58e-145 430.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_249739_2 469610.HMPREF0189_01944 0.000242 43.5 COG2944@1|root,COG2944@2|Bacteria,1N5H0@1224|Proteobacteria,2VW7F@28216|Betaproteobacteria,1KMQZ@119065|unclassified Burkholderiales 28216|Betaproteobacteria K Antitoxin component of bacterial toxin-antitoxin system, MqsA - - - ko:K07726 - - - - ko00000,ko03000 - - - HTH_3,HTH_31,MqsA_antitoxin k59_9262_1 145579.CAPSD_BPPHM 1.15e-50 177.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_83798_2 749414.SBI_08575 5.96e-54 188.0 COG0438@1|root,COG0438@2|Bacteria,2HH27@201174|Actinobacteria 201174|Actinobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 k59_158387_1 1165094.RINTHH_3920 1.96e-50 172.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_17329_1 1123508.JH636451_gene6021 1.22e-29 119.0 COG3864@1|root,COG3864@2|Bacteria 2|Bacteria S Putative metallopeptidase domain - - - - - - - - - - - - DUF2201,DUF2201_N k59_118325_1 1128421.JAGA01000002_gene516 8.67e-20 90.5 COG1351@1|root,COG1351@2|Bacteria,2NPQ2@2323|unclassified Bacteria 2|Bacteria F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant thyX - 2.1.1.148 ko:K03465 ko00240,ko00670,ko01100,map00240,map00670,map01100 - R06613 RC00022,RC00332 ko00000,ko00001,ko01000 - - - HNH,Thy1 k59_17991_3 1121468.AUBR01000062_gene972 4.37e-14 73.2 28H9V@1|root,2Z7MH@2|Bacteria,1UFFG@1239|Firmicutes,24AMI@186801|Clostridia,42I8D@68295|Thermoanaerobacterales 186801|Clostridia - - - - - - - - - - - - - - - k59_109635_1 1121935.AQXX01000137_gene3938 1.56e-81 273.0 COG0503@1|root,COG0503@2|Bacteria 2|Bacteria F purine ribonucleoside salvage apt - 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 - R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 - - - Pribosyltran k59_143129_1 1094184.KWO_0108140 0.000277 43.1 COG0433@1|root,COG0433@2|Bacteria,1QTVP@1224|Proteobacteria,1T1IQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Zonular occludens toxin (Zot) - - - ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko02042 - - - Zot k59_134841_1 1788445.A0A190WHA3_9CIRC 3.19e-32 124.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_134841_2 1788455.A0A190WHF5_9CIRC 2.66e-17 82.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_175845_1 1500301.JQMF01000006_gene1755 7.34e-28 112.0 28MSK@1|root,2ZB0X@2|Bacteria,1R7CY@1224|Proteobacteria,2U2MY@28211|Alphaproteobacteria,4BJ92@82115|Rhizobiaceae 28211|Alphaproteobacteria S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_175845_2 665942.HMPREF1022_03280 4.89e-11 68.9 2DUXE@1|root,32UY2@2|Bacteria,1N2YI@1224|Proteobacteria,430A8@68525|delta/epsilon subdivisions,2WVIN@28221|Deltaproteobacteria,2MCZ8@213115|Desulfovibrionales 28221|Deltaproteobacteria S Phage T7 capsid assembly protein - - - - - - - - - - - - Phage_T7_Capsid k59_118457_3 243233.MCA1735 1.32e-30 123.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,1XDRQ@135618|Methylococcales 135618|Methylococcales L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_10023_5 1123504.JQKD01000005_gene4830 7.35e-15 71.6 2EN2V@1|root,33FR1@2|Bacteria,1NJXZ@1224|Proteobacteria,2W3KD@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_35126_1 412597.AEPN01000059_gene3564 6.29e-103 324.0 COG3505@1|root,COG3505@2|Bacteria 412597.AEPN01000059_gene3564|- U unidirectional conjugation - - - - - - - - - - - - - k59_93780_2 428125.CLOLEP_01417 3.32e-27 108.0 2CGG9@1|root,2ZVSJ@2|Bacteria,1V633@1239|Firmicutes,24HD0@186801|Clostridia,3WMXK@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_209618_1 1476391.X5KCD8_9CAUD 7.67e-13 70.1 4QFCU@10239|Viruses,4QVYH@35237|dsDNA viruses no RNA stage,4QTFF@28883|Caudovirales,4QNUH@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_226822_1 1618251.A0A0C5I2L8_9CIRC 2.3e-22 102.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_243140_1 509191.AEDB02000081_gene2502 1.06e-16 85.1 COG1793@1|root,COG1793@2|Bacteria,1TTEP@1239|Firmicutes,258XM@186801|Clostridia,3WNZJ@541000|Ruminococcaceae 186801|Clostridia L ATP dependent DNA ligase C terminal region - - - - - - - - - - - - DNA_ligase_A_C,DNA_ligase_A_M k59_102345_1 1609634.A0A0C5AFV4_9VIRU 4.76e-16 77.4 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_77602_1 1121022.ABENE_05670 1.25e-11 70.5 COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,2TT03@28211|Alphaproteobacteria,2KFU8@204458|Caulobacterales 204458|Caulobacterales L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA - - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N k59_35898_1 272134.KB731324_gene2733 1.34e-20 94.0 COG4834@1|root,COG4834@2|Bacteria 2|Bacteria S Uncharacterized protein conserved in bacteria (DUF2184) VY92_02880 - - - - - - - - - - - DUF2184 k59_78348_3 1986029.Q9MBM8_9VIRU 1.5e-51 179.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_45295_1 1095743.HMPREF1054_1761 3.44e-12 70.1 COG1196@1|root,COG3941@1|root,COG1196@2|Bacteria,COG3941@2|Bacteria,1R19H@1224|Proteobacteria,1T4WY@1236|Gammaproteobacteria 1236|Gammaproteobacteria D Prophage tail length tape measure protein - - - - - - - - - - - - TMP_2 k59_4362_1 1385658.U5KPZ6_9VIRU 4.49e-130 391.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_19625_3 10678.Q71T83_BPP1 2.62e-13 74.3 4QEAQ@10239|Viruses,4QVWS@35237|dsDNA viruses no RNA stage,4QQWE@28883|Caudovirales 28883|Caudovirales S transferase activity, transferring glycosyl groups - - - - - - - - - - - - - k59_210386_8 1005048.CFU_0041 5.95e-37 132.0 COG0279@1|root,COG0279@2|Bacteria,1NVIE@1224|Proteobacteria,2W93C@28216|Betaproteobacteria,47711@75682|Oxalobacteraceae 28216|Betaproteobacteria G SIS domain - - 5.3.1.28 ko:K03271 ko00540,ko01100,map00540,map01100 M00064 R05645,R09768,R09769 RC00434 ko00000,ko00001,ko00002,ko01000,ko01005 - - - SIS_2 k59_128639_2 76869.PputGB1_1755 1.62e-22 99.0 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,1RR0M@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_61096_1 1692253.A0A0K1RLM4_9CIRC 2.53e-21 99.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_53774_1 398767.Glov_2811 2.8e-18 94.0 COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria 1224|Proteobacteria M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - - - - - - - - - - Rod-binding,SLT k59_4550_1 1177181.T9A_00229 5.82e-33 133.0 COG2946@1|root,COG2946@2|Bacteria,1RDKM@1224|Proteobacteria,1S7EJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Replication initiation factor - - - - - - - - - - - - Rep_trans k59_53940_1 194867.ALBQ01000016_gene3018 1.91e-91 288.0 COG4653@1|root,COG4653@2|Bacteria,1Q3BS@1224|Proteobacteria,2TW86@28211|Alphaproteobacteria,2K50B@204457|Sphingomonadales 204457|Sphingomonadales S Phage capsid family - - - - - - - - - - - - Phage_capsid k59_145505_3 979533.F1D0U3_9CAUD 5.59e-05 43.9 4QAM4@10239|Viruses,4QWEA@35237|dsDNA viruses no RNA stage,4QPGM@28883|Caudovirales,4QNJD@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_227868_1 1692255.A0A0K1RL52_9CIRC 7.21e-31 124.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_112004_1 388399.SSE37_18682 8.89e-26 115.0 COG0553@1|root,COG0553@2|Bacteria,1MV6M@1224|Proteobacteria,2TU4W@28211|Alphaproteobacteria 28211|Alphaproteobacteria L COG0553 Superfamily II DNA RNA helicases, SNF2 family - - - - - - - - - - - - Helicase_C,SNF2_N k59_45531_1 1692257.A0A0K1RL39_9CIRC 1.8e-10 61.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_95370_2 49964.Q94MS1_9CAUD 1.58e-129 379.0 4QB4H@10239|Viruses,4QYQI@35237|dsDNA viruses no RNA stage,4QUAR@28883|Caudovirales,4QNUV@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_20667_7 272942.RCAP_rcc00971 6.06e-66 216.0 28M7D@1|root,2ZAKV@2|Bacteria,1R6BC@1224|Proteobacteria,2U3UN@28211|Alphaproteobacteria,1FCRU@1060|Rhodobacter 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_20667_10 1517681.HW45_02700 7.8e-43 176.0 COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,1QZAD@1224|Proteobacteria,1RYP3@1236|Gammaproteobacteria 1236|Gammaproteobacteria D nuclear chromosome segregation - - - - - - - - - - - - - k59_20667_13 1121935.AQXX01000130_gene2403 1.24e-12 82.0 COG4733@1|root,COG4733@2|Bacteria,1R77Q@1224|Proteobacteria,1S1WT@1236|Gammaproteobacteria,1XMZT@135619|Oceanospirillales 135619|Oceanospirillales D Fibronectin type 3 domain - - - - - - - - - - - - - k59_20667_16 675812.VHA_000295 5.45e-12 66.6 2DMPB@1|root,32SV8@2|Bacteria,1NHUE@1224|Proteobacteria,1SIKI@1236|Gammaproteobacteria,1XY3E@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k59_236187_3 1095772.CAHH01000068_gene334 2.59e-08 54.3 2C4MW@1|root,32RKK@2|Bacteria,2IQ6A@201174|Actinobacteria 201174|Actinobacteria S pathogenesis lsr - - - - - - - - - - - Lsr2 k59_12767_1 1041826.FCOL_05440 1.7e-27 108.0 COG0270@1|root,COG0270@2|Bacteria,4P351@976|Bacteroidetes,1I9UJ@117743|Flavobacteriia,2NZ0G@237|Flavobacterium 976|Bacteroidetes L C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_154548_1 1123487.KB892865_gene1380 3.62e-53 187.0 COG3170@1|root,COG3170@2|Bacteria,1PMRK@1224|Proteobacteria,2W7ZG@28216|Betaproteobacteria,2KZB6@206389|Rhodocyclales 206389|Rhodocyclales NU Tfp pilus assembly protein FimV - - - - - - - - - - - - - k59_171205_1 1618247.A0A0C5I2K0_9CIRC 4.36e-82 258.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_121406_3 1385658.U5KPZ6_9VIRU 1.68e-79 254.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_211411_2 1327981.S0A1R5_9CAUD 8.18e-25 118.0 4QGUS@10239|Viruses,4QX38@35237|dsDNA viruses no RNA stage,4QRVV@28883|Caudovirales,4QN8J@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_54896_1 156889.Mmc1_2604 1.06e-68 226.0 COG1475@1|root,COG4725@1|root,COG1475@2|Bacteria,COG4725@2|Bacteria,1R553@1224|Proteobacteria,2TRP6@28211|Alphaproteobacteria 28211|Alphaproteobacteria KT Belongs to the MT-A70-like family - - - - - - - - - - - - MT-A70 k59_54896_2 571166.KI421509_gene3812 1.96e-30 115.0 28PMA@1|root,2ZCAD@2|Bacteria,1RARQ@1224|Proteobacteria,2U6X3@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_71238_1 742740.HMPREF9474_02271 5.61e-39 143.0 28J3N@1|root,2Z8ZU@2|Bacteria,1V15Z@1239|Firmicutes,249Z0@186801|Clostridia,221RR@1506553|Lachnoclostridium 186801|Clostridia S Phage portal protein - - - - - - - - - - - - Phage_portal k59_71238_2 691965.D4P7D6_9CAUD 9.52e-19 85.9 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_221696_2 688245.CtCNB1_1537 3.97e-46 162.0 2DZXB@1|root,32VME@2|Bacteria,1N191@1224|Proteobacteria,2VT36@28216|Betaproteobacteria,4AII6@80864|Comamonadaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_244674_2 1415148.V5Q7E3_9CAUD 1.94e-37 144.0 4QGPT@10239|Viruses,4QQI9@28883|Caudovirales,4QMUP@10699|Siphoviridae 10699|Siphoviridae S DNA catabolic process, endonucleolytic - - - - - - - - - - - - - k59_244674_3 202954.BBNK01000034_gene3794 6.35e-38 131.0 2A3Q7@1|root,30S7S@2|Bacteria,1NP2K@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_244674_5 1280689.AUJC01000003_gene948 6.86e-14 69.3 COG1475@1|root,COG1475@2|Bacteria,1TPT0@1239|Firmicutes,25D1W@186801|Clostridia,36U5S@31979|Clostridiaceae 186801|Clostridia K Domain of Unknown Function with PDB structure (DUF3850) - - - - - - - - - - - - DUF3850 k59_172395_3 1609634.A0A0C5ANA6_9VIRU 1.95e-09 57.8 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_148084_1 1452718.JBOY01000137_gene1482 3.14e-147 444.0 COG3170@1|root,COG3170@2|Bacteria 2|Bacteria NU translation initiation factor activity - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - DUF5067,P22_portal,Pkinase k59_48067_1 77856.REP_BFDV 2.15e-12 67.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_223003_2 1496688.ER33_05835 5.12e-27 122.0 COG0553@1|root,COG0553@2|Bacteria,1GHHG@1117|Cyanobacteria,22RNR@167375|Cyanobium 1117|Cyanobacteria F SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,SNF2_N k59_155728_1 105154.Q9MBU6_9VIRU 1.43e-13 70.5 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_155728_3 1165094.RINTHH_3920 1.72e-79 250.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_212436_1 555088.DealDRAFT_0440 1.4e-36 140.0 COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,247SF@186801|Clostridia,42JND@68298|Syntrophomonadaceae 186801|Clostridia L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA - - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA k59_229923_1 1430440.MGMSRv2_0692 1.08e-50 176.0 COG0270@1|root,COG0270@2|Bacteria,1MV9H@1224|Proteobacteria,2U64S@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_87732_1 1692249.A0A0K1RLN8_9CIRC 7.46e-22 93.6 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_96568_1 1986029.Q9MBM3_9VIRU 5.66e-26 108.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_96568_3 1609634.A0A0C5AFV4_9VIRU 4.55e-20 89.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_56131_1 1618259.A0A0C5I2B5_9CIRC 2.03e-70 226.0 4QE84@10239|Viruses,4QUKR@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_13800_1 652103.Rpdx1_2530 2.8e-30 117.0 2C22H@1|root,30QGD@2|Bacteria,1N9T4@1224|Proteobacteria,2UFYM@28211|Alphaproteobacteria,3K24J@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Chaperone of endosialidase - - - - - - - - - - - - Peptidase_S74 k59_197057_1 1692249.A0A0K1RLN8_9CIRC 4.53e-25 105.0 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_206416_1 1089447.RHAA1_05308 0.000258 50.4 COG5281@1|root,COG5281@2|Bacteria,1MX2R@1224|Proteobacteria,1S3MM@1236|Gammaproteobacteria,1Y73U@135625|Pasteurellales 135625|Pasteurellales S tail length tape measure protein - - - - - - - - - - - - - k59_264325_2 259536.Psyc_0471 7.45e-05 45.8 COG4197@1|root,COG4197@2|Bacteria,1QQQK@1224|Proteobacteria,1RTCW@1236|Gammaproteobacteria,3NSJX@468|Moraxellaceae 1236|Gammaproteobacteria S Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT - - - - - - - - - - - - YdaS_antitoxin k59_264325_4 626887.J057_01855 1.86e-46 159.0 COG3756@1|root,COG3756@2|Bacteria,1R95D@1224|Proteobacteria,1RQF3@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF1376) - - - - - - - - - - - - DUF1376 k59_149141_1 444861.E3SPN9_9CAUD 4.82e-171 514.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales 28883|Caudovirales S DNA polymerase family B - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016032,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019058,GO:0019079,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0039686,GO:0039693,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044403,GO:0044419,GO:0046483,GO:0051704,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_49433_1 1385658.U5KNR1_9VIRU 6.68e-57 190.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_57122_2 504472.Slin_0994 1.8e-25 109.0 COG1858@1|root,COG1858@2|Bacteria,4NE50@976|Bacteroidetes,47KXQ@768503|Cytophagia 976|Bacteroidetes C cytochrome c peroxidase - - 1.11.1.5 ko:K00428 - - - - ko00000,ko01000 - - - CCP_MauG k59_238286_1 216596.RL3938 5.13e-17 80.9 COG4626@1|root,COG4626@2|Bacteria,1R2FH@1224|Proteobacteria,2UCW2@28211|Alphaproteobacteria,4BCYA@82115|Rhizobiaceae 28211|Alphaproteobacteria S Terminase - - - - - - - - - - - - - k59_238286_2 1122164.JHWF01000003_gene2091 7.35e-22 92.0 2D0K9@1|root,32T8S@2|Bacteria,1MZRW@1224|Proteobacteria,1SF0N@1236|Gammaproteobacteria,1JEKY@118969|Legionellales 118969|Legionellales - - - - - - - - - - - - - - - k59_181369_1 1234888.K0A2J2_9VIRU 9.27e-44 160.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_173822_3 1055815.AYYA01000027_gene574 5.61e-142 410.0 COG5527@1|root,COG5527@2|Bacteria,1RD9C@1224|Proteobacteria,1T07W@1236|Gammaproteobacteria,3NTFJ@468|Moraxellaceae 1236|Gammaproteobacteria L Initiator Replication protein - - - - - - - - - - - - Rep_3 k59_39714_4 1385658.U5KPZ6_9VIRU 1.43e-72 237.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_197218_5 634504.Bgr_10230 7.25e-36 130.0 COG3772@1|root,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,2U7X4@28211|Alphaproteobacteria,48TF4@772|Bartonellaceae 28211|Alphaproteobacteria G Phage lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_156792_2 160488.PP_2273 9.16e-63 215.0 COG0749@1|root,COG0749@2|Bacteria,1P27P@1224|Proteobacteria,1SJP1@1236|Gammaproteobacteria 1236|Gammaproteobacteria L DNA polymerase family A - - - - - - - - - - - - DNA_pol_A k59_197222_1 1120792.JAFV01000001_gene3400 2.45e-25 108.0 COG4951@1|root,COG4951@2|Bacteria 2|Bacteria - - XK27_08510 - - ko:K06919 - - - - ko00000 - - - DUF1882,Helicase_C,ResIII k59_246687_1 882.DVU_1515 2.59e-78 253.0 COG0270@1|root,COG0270@2|Bacteria,1PPPB@1224|Proteobacteria,43A4E@68525|delta/epsilon subdivisions,2WUDB@28221|Deltaproteobacteria,2MB1N@213115|Desulfovibrionales 28221|Deltaproteobacteria L C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_213524_1 1692250.A0A0K1RLR1_9CIRC 6.05e-23 98.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_64122_1 1437824.BN940_02906 1.05e-41 159.0 COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,1MVH7@1224|Proteobacteria,2VKJR@28216|Betaproteobacteria,3T6AP@506|Alcaligenaceae 28216|Betaproteobacteria KL DNA methylase yhdJ - - - - - - - - - - - N6_N4_Mtase,ParBc k59_264491_3 742740.HMPREF9474_04482 3.6e-07 56.6 COG0827@1|root,COG2003@1|root,COG4227@1|root,COG4734@1|root,COG0827@2|Bacteria,COG2003@2|Bacteria,COG4227@2|Bacteria,COG4734@2|Bacteria,1TQN4@1239|Firmicutes,2482H@186801|Clostridia,21ZD6@1506553|Lachnoclostridium 186801|Clostridia L Antirestriction protein (ArdA) - - - - - - - - - - - - ArdA,DUF4316,Peptidase_M78,YodL k59_140511_2 710111.FraQA3DRAFT_0908 1.89e-10 62.4 COG0791@1|root,COG0791@2|Bacteria 2|Bacteria M cysteine-type peptidase activity - - - - - - - - - - - - NLPC_P60,Peptidase_M23,SLT k59_124050_1 1173020.Cha6605_4560 1.77e-08 57.8 COG1061@1|root,COG1061@2|Bacteria,1G2HP@1117|Cyanobacteria 1117|Cyanobacteria L Type III restriction enzyme res subunit - - - - - - - - - - - - Helicase_C,ResIII k59_265005_4 105154.Q9MBU6_9VIRU 6.08e-224 636.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_265005_5 105154.Q9MBT9_9VIRU 1e-07 53.9 4QCC5@10239|Viruses,4QUKW@29258|ssDNA viruses,4QP4C@10841|Microviridae 10841|Microviridae S viral process - - - - - - - - - - - - - k59_256637_1 105154.Q9MBU6_9VIRU 8.1e-43 154.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_82848_1 1385658.U5KPZ6_9VIRU 9.69e-62 207.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_24687_2 1458462.JNLK01000001_gene1293 0.000221 44.3 COG3773@1|root,COG5263@1|root,COG3773@2|Bacteria,COG5263@2|Bacteria 2|Bacteria S dextransucrase activity - - 3.5.1.28 ko:K01449 - - R04112 RC00064,RC00141 ko00000,ko01000 - - - CW_binding_1,Hydrolase_2,SH3_3 k59_265006_1 1618260.A0A0C5I2C5_9CIRC 6.8e-52 177.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_16254_3 1096546.WYO_4111 3.67e-27 110.0 2EK50@1|root,33DVF@2|Bacteria,1NK6R@1224|Proteobacteria,2TYQN@28211|Alphaproteobacteria,1JZK7@119045|Methylobacteriaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_265007_1 1100721.ALKO01000041_gene5 1.17e-28 115.0 2EZCX@1|root,33SI7@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_165792_1 595460.RRSWK_03642 2.39e-13 75.5 2DME6@1|root,32QWJ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_256667_1 290317.Cpha266_2236 5.92e-08 58.2 COG1573@1|root,COG1573@2|Bacteria 2|Bacteria L deaminated base DNA N-glycosylase activity - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k59_41117_2 1396418.BATQ01000041_gene6240 1.1e-23 105.0 COG4675@1|root,COG4675@2|Bacteria,46X85@74201|Verrucomicrobia,2IUYY@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Phage Tail Collar Domain - - - - - - - - - - - - Collar k59_41117_3 1458697.W6EKG4_9CAUD 1.53e-08 62.8 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QM2K@10699|Siphoviridae 10699|Siphoviridae S Phage Tail Collar Domain - - - - - - - - - - - - - k59_198636_2 1419711.U6BML2_9CIRC 1.05e-24 109.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_65545_1 981335.G4W934_9CAUD 1.42e-69 218.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales 28883|Caudovirales S N-methyltransferase activity - - - - - - - - - - - - - k59_265060_2 1618247.A0A0C5IMK7_9CIRC 1e-09 65.1 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_198883_1 875328.JDM601_0775 1.92e-23 106.0 2EP1Y@1|root,33GNT@2|Bacteria,2IC2I@201174|Actinobacteria,2380S@1762|Mycobacteriaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_98932_1 1232410.KI421412_gene256 1.84e-82 259.0 COG0500@1|root,COG0500@2|Bacteria,1MVD1@1224|Proteobacteria 1224|Proteobacteria Q methyltransferase - - - - - - - - - - - - Methyltransf_13,Methyltransf_14,Methyltransf_23 k59_157922_4 1035839.AFNK01000079_gene51 2.17e-75 246.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,1RMPV@1236|Gammaproteobacteria,1Y7PP@135625|Pasteurellales 135625|Pasteurellales F Ribonucleotide reductase, alpha subunit - - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_lgC k59_91662_1 105154.Q9MBU0_9VIRU 4.42e-16 82.8 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_91662_3 1234888.K0A2J2_9VIRU 5.33e-151 446.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_41952_1 948071.S4S2D9_9CAUD 2.48e-130 393.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QNQ6@10744|Podoviridae 10744|Podoviridae S ribonucleoside-triphosphate reductase activity - - - - - - - - - - - - - k59_25389_2 115711.CP_0543 8.47e-13 71.2 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_25389_6 1609634.A0A0C5AFV4_9VIRU 1.84e-212 607.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_8760_2 1526550.A0A088F6W1_9VIRU 4.87e-23 107.0 4QAK6@10239|Viruses 10239|Viruses S N-acetylmuramoyl-L-alanine amidase activity - - - - - - - - - - - - - k59_232643_2 665942.HMPREF1022_01523 9.48e-19 86.3 2E16H@1|root,32WMB@2|Bacteria,1N6EU@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_141401_1 490103.B0FIJ6_BPE32 1.1e-16 84.0 4QDGP@10239|Viruses,4QZGF@35237|dsDNA viruses no RNA stage,4QSDY@28883|Caudovirales,4QNCJ@10744|Podoviridae 10744|Podoviridae S ATP binding - - - - - - - - - - - - - k59_133204_1 1114964.L485_16305 1.18e-05 49.3 2E46I@1|root,332Q5@2|Bacteria,1NFBY@1224|Proteobacteria,2UFWQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_75115_2 1122243.KB903794_gene1727 4.15e-65 217.0 COG0582@1|root,COG0582@2|Bacteria,1MVZB@1224|Proteobacteria,1RP4Y@1236|Gammaproteobacteria,3NK6F@468|Moraxellaceae 1236|Gammaproteobacteria L Belongs to the 'phage' integrase family - - - ko:K14059 - - - - ko00000 - - - Arm-DNA-bind_2,Phage_integrase k59_58547_13 883156.HMPREF9282_00941 1.18e-48 181.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4H2W4@909932|Negativicutes 909932|Negativicutes L SNF2 family - - - - - - - - - - - - Helicase_C,SNF2_N k59_108335_1 1298608.JCM18900_11654 5.51e-44 145.0 COG3136@1|root,COG3136@2|Bacteria,1RH8C@1224|Proteobacteria,1S69X@1236|Gammaproteobacteria,3NNYE@468|Moraxellaceae 1236|Gammaproteobacteria S GlpM protein ydgC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02442 - - - - ko00000 - - - GlpM k59_207770_1 488538.SAR116_0376 2.76e-53 187.0 COG3064@1|root,COG3064@2|Bacteria,1R6JV@1224|Proteobacteria,2U5NE@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Membrane - - - - - - - - - - - - - k59_216224_2 1327981.S0A1R5_9CAUD 7.8e-36 151.0 4QGUS@10239|Viruses,4QX38@35237|dsDNA viruses no RNA stage,4QRVV@28883|Caudovirales,4QN8J@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_125065_3 1123392.AQWL01000004_gene2557 5.12e-39 149.0 COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,2VS6Y@28216|Betaproteobacteria 28216|Betaproteobacteria S Putative metallopeptidase domain - - - - - - - - - - - - DUF2201,DUF2201_N k59_133337_13 192875.XP_004364110.1 5.77e-25 112.0 COG1793@1|root,2QTYC@2759|Eukaryota,38GKG@33154|Opisthokonta 33154|Opisthokonta L DNA ligase OB-like domain - - 6.5.1.1,6.5.1.6,6.5.1.7 ko:K10747 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00381,R00382,R10822,R10823 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_A_M,DNA_ligase_OB_2,zf-CCHH k59_175037_2 1234888.K0A2J2_9VIRU 8.17e-146 433.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_17572_1 1498011.A0A096XUU0_9CAUD 2.41e-169 483.0 4QG38@10239|Viruses,4QQVI@28883|Caudovirales,4QNWM@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_1542_2 428125.CLOLEP_01405 5.24e-34 122.0 2AIHK@1|root,318ZG@2|Bacteria,1V7P0@1239|Firmicutes,24KNU@186801|Clostridia,3WNH7@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_183604_3 1618248.A0A0C5IB82_9CIRC 2.83e-55 188.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_175134_2 105154.Q9MBU0_9VIRU 2.62e-40 151.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_51124_1 985762.SAGN_03435 3.49e-19 89.0 COG4112@1|root,COG4112@2|Bacteria,1V277@1239|Firmicutes,4HGGN@91061|Bacilli,4GXK2@90964|Staphylococcaceae 91061|Bacilli S DNA mismatch repair protein MutT ymaB - - - - - - - - - - - NUDIX k59_51124_4 634452.APA01_03450 1.73e-13 71.6 COG0741@1|root,COG0741@2|Bacteria,1N0U8@1224|Proteobacteria,2UICK@28211|Alphaproteobacteria,2JTZJ@204441|Rhodospirillales 204441|Rhodospirillales M lytic transglycosylase activity - - - - - - - - - - - - - k59_51124_6 1429767.W6B150_9CAUD 4e-41 155.0 4QF3C@10239|Viruses,4QWIA@35237|dsDNA viruses no RNA stage,4QU4U@28883|Caudovirales,4QNNQ@10744|Podoviridae 10744|Podoviridae S host cell wall - - - - - - - - - - - - - k59_117500_2 257310.BB3501 1.9e-149 429.0 COG5492@1|root,COG5492@2|Bacteria,1R69J@1224|Proteobacteria,2VNT9@28216|Betaproteobacteria 28216|Betaproteobacteria N to Yersinia pestis phage protein ypo2110 SWALL Q8ZEQ0 (EMBL AJ414151) (401 aa) fasta scores E() 1.1e-09, 27.98 id in 318 aa - - - - - - - - - - - - - k59_217154_1 1385658.U5KNR1_9VIRU 2.8e-36 134.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_17573_1 1673638.A0A0H4AJL5_9CIRC 7.51e-23 102.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_67616_1 1234888.K0A2J2_9VIRU 4.84e-130 391.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_158594_1 1219031.BBJR01000069_gene1085 5.69e-06 55.5 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2VJ57@28216|Betaproteobacteria,4AAFC@80864|Comamonadaceae 28216|Betaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_135129_3 1122947.FR7_2541 1.01e-13 77.8 COG4675@1|root,COG4675@2|Bacteria,1UNQW@1239|Firmicutes,4H9I3@909932|Negativicutes 909932|Negativicutes S tail collar domain protein - - - - - - - - - - - - - k59_93262_1 742733.HMPREF9469_05026 9.44e-78 239.0 28NM4@1|root,2ZBMQ@2|Bacteria,1V1QD@1239|Firmicutes,24G1B@186801|Clostridia,221N8@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_151751_2 1609634.A0A0C5AFT2_9VIRU 7.12e-98 296.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_192530_2 641112.ACOK01000086_gene3447 1.45e-07 55.5 COG3866@1|root,COG4677@1|root,COG3866@2|Bacteria,COG4677@2|Bacteria,1TSCD@1239|Firmicutes,24AHP@186801|Clostridia,3WHG8@541000|Ruminococcaceae 186801|Clostridia G Pectinesterase - - - - - - - - - - - - Pectinesterase k59_10213_1 105154.Q9MBU6_9VIRU 3.52e-53 186.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_18335_1 78345.BMERY_1221 9.35e-05 51.6 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2GJY2@201174|Actinobacteria,4CYVK@85004|Bifidobacteriales 201174|Actinobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_209155_1 375286.mma_2206 5.58e-117 355.0 COG5323@1|root,COG5323@2|Bacteria 2|Bacteria M Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6 k59_209155_2 49964.Q94MS4_9CAUD 2.64e-32 130.0 4QCUF@10239|Viruses,4QV7U@35237|dsDNA viruses no RNA stage,4QQ89@28883|Caudovirales,4QNCY@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_143553_2 445970.ALIPUT_01612 3.36e-90 280.0 COG0270@1|root,COG0270@2|Bacteria,4NJPP@976|Bacteroidetes,2FKYT@200643|Bacteroidia 976|Bacteroidetes H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_233939_2 160799.PBOR_32325 3.73e-09 60.1 COG5301@1|root,COG5301@2|Bacteria 2|Bacteria G cellulose 1,4-beta-cellobiosidase activity - - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - DUF2793,Phage_fiber_2 k59_101854_1 490913.C4NTE0_9CAUD 3.03e-90 305.0 4QAXA@10239|Viruses,4QYJI@35237|dsDNA viruses no RNA stage,4QQ1A@28883|Caudovirales,4QNU7@10744|Podoviridae 10744|Podoviridae S metallopeptidase activity - - - - - - - - - - - - - k59_184608_2 1618238.A0A0C5IB41_9CIRC 9.56e-08 58.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_234882_1 1385658.U5KPZ6_9VIRU 5.86e-52 179.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_234882_5 1609634.A0A0C5AFT2_9VIRU 1.19e-59 200.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_234882_8 1385658.U5KPZ6_9VIRU 6.92e-74 240.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_243527_1 762968.HMPREF9441_02243 4.56e-07 55.5 COG1100@1|root,COG1100@2|Bacteria,4NEXY@976|Bacteroidetes,2FRU5@200643|Bacteroidia 976|Bacteroidetes S AAA domain - - - - - - - - - - - - AAA_24 k59_169727_1 2003327.CAPSD_BPCHP 5.34e-20 89.7 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_169727_2 1609634.A0A0C5ANA6_9VIRU 2.59e-07 57.4 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_169727_7 1385658.U5KPZ6_9VIRU 7.35e-130 393.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_28820_2 1475143.W8SNN0_9CIRC 2.44e-47 167.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_60997_1 1121935.AQXX01000130_gene2403 2.74e-35 149.0 COG4733@1|root,COG4733@2|Bacteria,1R77Q@1224|Proteobacteria,1S1WT@1236|Gammaproteobacteria,1XMZT@135619|Oceanospirillales 135619|Oceanospirillales D Fibronectin type 3 domain - - - - - - - - - - - - - k59_111629_2 428125.CLOLEP_01425 1.24e-22 98.2 292XD@1|root,2ZQEV@2|Bacteria,1V48I@1239|Firmicutes,24GZD@186801|Clostridia,3WNVV@541000|Ruminococcaceae 186801|Clostridia S COG NOG18825 non supervised orthologous group - - - - - - - - - - - - - k59_11381_2 1609634.A0A0C5AFV4_9VIRU 2.86e-34 130.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_94338_1 1185766.DL1_08470 1.95e-15 81.3 291GM@1|root,2ZP3A@2|Bacteria,1RD1E@1224|Proteobacteria,2UPJH@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_94338_2 948071.S4S2L2_9CAUD 1.3e-05 55.1 4QHQ5@10239|Viruses,4QR7K@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_78210_1 411460.RUMTOR_01333 0.000428 44.7 28K55@1|root,2Z9TX@2|Bacteria,1V0P7@1239|Firmicutes,24DCX@186801|Clostridia,3Y0KI@572511|Blautia 186801|Clostridia S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - Sipho_Gp37 k59_171099_1 1732201.A0A0N9N7I3_9CIRC 4.94e-19 94.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_129834_2 1692244.A0A0K1RLR5_9CIRC 3.72e-36 137.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_146582_1 1788454.A0A190WHE4_9CIRC 1.67e-06 54.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_137724_2 742733.HMPREF9469_05062 3.5e-162 468.0 COG0553@1|root,COG0553@2|Bacteria,1TS9W@1239|Firmicutes,24CGX@186801|Clostridia,222GT@1506553|Lachnoclostridium 186801|Clostridia KL Helicase conserved C-terminal domain - - - - - - - - - - - - - k59_137724_4 742740.HMPREF9474_02280 3.52e-21 85.9 2CGGB@1|root,32UNH@2|Bacteria,1VD9W@1239|Firmicutes,24MWC@186801|Clostridia,2235P@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_261953_1 686340.Metal_4010 6.61e-58 188.0 COG1192@1|root,COG1192@2|Bacteria,1MWRE@1224|Proteobacteria,1RTVR@1236|Gammaproteobacteria,1XGRQ@135618|Methylococcales 135618|Methylococcales D Anion-transporting ATPase - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 k59_178886_1 1894.JOER01000003_gene2915 3.64e-11 75.9 COG3291@1|root,COG3291@2|Bacteria,2GKNE@201174|Actinobacteria 201174|Actinobacteria NU Collagenase - - - - - - - - - - - - PKD,Peptidase_M9,Peptidase_M9_N k59_236067_4 1037409.BJ6T_71280 2.67e-50 172.0 COG1215@1|root,COG1215@2|Bacteria,1NNZS@1224|Proteobacteria,2UQV9@28211|Alphaproteobacteria,3K2N5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Glycosyl transferase family 2 - - - - - - - - - - - - Glyco_tranf_2_4 k59_79226_1 1316936.K678_00245 9.76e-39 134.0 2AJ1X@1|root,319K5@2|Bacteria,1RK0X@1224|Proteobacteria,2UKUD@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF2829) - - - - - - - - - - - - DUF2829 k59_137730_1 756883.Halar_0333 3.05e-07 57.8 COG4983@1|root,arCOG06276@2157|Archaea 2157|Archaea L peptidase activity - - - ko:K06919 - - - - ko00000 - - - - k59_12807_1 1120936.KB907208_gene1107 7.81e-24 102.0 COG0209@1|root,COG0209@2|Bacteria,2IC1H@201174|Actinobacteria 201174|Actinobacteria F Ribonucleotide reductase, barrel domain - - - - - - - - - - - - Ribonuc_red_lgC k59_154586_1 1423144.Gal_02289 1.45e-66 210.0 COG0417@1|root,COG0417@2|Bacteria,1QVEF@1224|Proteobacteria,2UA8B@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DNA polymerase family B, exonuclease domain - - - ko:K07501 - - - - ko00000 - - - DNA_pol_B_exo2 k59_79382_2 314264.ROS217_23397 0.000767 43.1 2AEGK@1|root,314BR@2|Bacteria,1PTVU@1224|Proteobacteria,2UJWI@28211|Alphaproteobacteria,46R9X@74030|Roseovarius 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_87534_13 136993.KB900626_gene2754 1.04e-17 75.9 2ENGU@1|root,33G4B@2|Bacteria,1NIKW@1224|Proteobacteria,2UWRG@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_87534_20 525898.Sdel_1112 2.56e-14 81.6 COG0582@1|root,COG0582@2|Bacteria,1MVZB@1224|Proteobacteria,42M9T@68525|delta/epsilon subdivisions,2YNIB@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria L Belongs to the 'phage' integrase family - - - ko:K14059 - - - - ko00000 - - - Phage_int_SAM_3,Phage_integrase k59_105175_1 1249627.D779_2292 1.48e-05 56.6 COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,1R97W@1224|Proteobacteria,1TK9M@1236|Gammaproteobacteria,1X0PG@135613|Chromatiales 135613|Chromatiales D Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_188724_2 2003327.CAPSD_BPCHP 2.51e-41 151.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_212327_1 942016.E9NIF8_9CAUD 3.36e-96 296.0 4QAR1@10239|Viruses,4QUNA@35237|dsDNA viruses no RNA stage,4QPJE@28883|Caudovirales,4QNDS@10744|Podoviridae 10744|Podoviridae S ATPase activity - - - - - - - - - - - - - k59_212327_2 1395983.A0A067Y168_9CAUD 5.19e-31 123.0 4QB3X@10239|Viruses,4QWKP@35237|dsDNA viruses no RNA stage,4QPEE@28883|Caudovirales,4QNCI@10744|Podoviridae 10744|Podoviridae S VWA-like domain (DUF2201) - - - - - - - - - - - - - k59_223076_1 691965.D4P7L7_9CAUD 8.93e-25 106.0 4QB9J@10239|Viruses,4QXFE@35237|dsDNA viruses no RNA stage,4QS1Z@28883|Caudovirales,4QN8F@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_223076_2 478749.BRYFOR_08535 9.98e-52 171.0 29YRZ@1|root,30KMY@2|Bacteria,1V4Y4@1239|Firmicutes,24HPY@186801|Clostridia 186801|Clostridia S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - DUF2800 k59_139251_1 1692246.A0A0K1RLM8_9CIRC 2.53e-23 95.9 4QBFZ@10239|Viruses,4QUKU@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_21740_1 1267533.KB906733_gene3172 6.52e-31 122.0 COG4653@1|root,COG4653@2|Bacteria 2|Bacteria G Phage capsid family xkdG - - - - - - - - - - - Phage_capsid k59_172497_2 1332071.L581_3156 2.05e-10 61.6 COG2189@1|root,COG2189@2|Bacteria,1QUB9@1224|Proteobacteria,1RMSJ@1236|Gammaproteobacteria,400M0@613|Serratia 1236|Gammaproteobacteria L DNA methylase - - 2.1.1.72 ko:K07319 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_122810_1 1140.Synpcc7942_0756 2.06e-22 93.6 COG3772@1|root,COG3772@2|Bacteria 2|Bacteria S cytolysis by virus of host cell - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_48165_1 1234888.K0A2J2_9VIRU 2.05e-114 347.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_180143_2 1121935.AQXX01000096_gene2550 6.68e-14 76.6 COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,1MVH7@1224|Proteobacteria,1S09Z@1236|Gammaproteobacteria,1XP1M@135619|Oceanospirillales 135619|Oceanospirillales KL DNA methylase - - - - - - - - - - - - N6_N4_Mtase,ParBc k59_139257_3 1215092.PA6_009_00300 6.65e-82 258.0 28JC4@1|root,2Z96S@2|Bacteria,1RI8W@1224|Proteobacteria,1S6FI@1236|Gammaproteobacteria 1236|Gammaproteobacteria S P22 coat protein-protein 5 domain protein - - - - - - - - - - - - - k59_223083_1 268748.Q58N42_BPPRP 1.32e-24 114.0 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales,4QNBW@10744|Podoviridae 10744|Podoviridae S DNA helicase activity - - - - - - - - - - - - - k59_22459_2 1611039.A0A0C5C3Z3_9CIRC 2.5e-57 193.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_156478_2 1232430.CAVG010000109_gene1001 4.13e-180 526.0 COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,4H9X0@91061|Bacilli,4GXM9@90964|Staphylococcaceae 91061|Bacilli F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdE - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - RNR_N,Ribonuc_red_lgC,Ribonuc_red_lgN k59_156478_3 1335757.SPICUR_08520 3.65e-130 380.0 COG0208@1|root,COG0208@2|Bacteria,1MWUS@1224|Proteobacteria,1RZEX@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Ribonucleotide reductase beta - - 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_sm k59_32402_1 1732201.A0A0N9N7I3_9CIRC 3.63e-13 75.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_189968_1 520999.PROVALCAL_01874 3.57e-24 108.0 28HCK@1|root,2Z7PE@2|Bacteria,1NK7S@1224|Proteobacteria,1S03Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_196682_4 935261.JAGL01000009_gene1157 9.32e-12 68.9 2ATMD@1|root,31J5V@2|Bacteria,1RH31@1224|Proteobacteria,2UBNT@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Tail tubular protein - - - - - - - - - - - - Tube k59_189970_1 1385658.U5KPZ6_9VIRU 1.76e-137 411.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_123501_1 2003327.CAPSD_BPCHP 8.94e-18 84.3 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_39305_1 1028800.RG540_CH13980 1.83e-55 190.0 COG5410@1|root,COG5410@2|Bacteria,1N0W2@1224|Proteobacteria,2U18J@28211|Alphaproteobacteria,4BHJS@82115|Rhizobiaceae 28211|Alphaproteobacteria K chromosome segregation - - - - - - - - - - - - Terminase_6C k59_131648_2 1500281.JQKZ01000050_gene4139 3.64e-14 78.2 COG0587@1|root,COG0587@2|Bacteria,4NFA0@976|Bacteroidetes,1HXPM@117743|Flavobacteriia,3ZNI6@59732|Chryseobacterium 976|Bacteroidetes L DNA-directed DNA polymerase dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon k59_131648_5 1286171.EAL2_c10940 8.32e-14 70.5 COG1694@1|root,COG1694@2|Bacteria,1VIQA@1239|Firmicutes,24SKH@186801|Clostridia 186801|Clostridia S MazG nucleotide pyrophosphohydrolase - - - - - - - - - - - - MazG k59_131648_6 362976.HQ_1364A 7.24e-27 122.0 COG0210@1|root,arCOG00797@2157|Archaea,2XUH7@28890|Euryarchaeota,23S3W@183963|Halobacteria 183963|Halobacteria L COG0210 Superfamily I DNA and RNA helicases uvrD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k59_173395_2 1609634.A0A0C5AFV4_9VIRU 4.04e-43 156.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_63715_1 411468.CLOSCI_01467 5.04e-38 133.0 COG4725@1|root,COG4725@2|Bacteria,1TSJV@1239|Firmicutes,248X5@186801|Clostridia,21ZSS@1506553|Lachnoclostridium 186801|Clostridia KT Belongs to the MT-A70-like family - - - - - - - - - - - - MT-A70 k59_207283_4 1396141.BATP01000035_gene4051 1.18e-33 128.0 COG4122@1|root,COG4122@2|Bacteria 2|Bacteria E O-methyltransferase activity - - - - - - - - - - - - Methyltransf_24 k59_264925_2 142661.REP_CACV 3.47e-31 126.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_57978_1 316278.SynRCC307_0266 3.41e-08 61.6 COG0859@1|root,COG0859@2|Bacteria,1GHF6@1117|Cyanobacteria,1GZMZ@1129|Synechococcus 1117|Cyanobacteria M PFAM glycosyl transferase family 9 - - - - - - - - - - - - Glyco_transf_9 k59_106925_2 665956.HMPREF1032_00687 3.65e-39 146.0 2E2JP@1|root,32XP4@2|Bacteria,1VAIM@1239|Firmicutes,24PPR@186801|Clostridia,3WI4W@541000|Ruminococcaceae 186801|Clostridia S Phage tail protein - - - - - - - - - - - - Sipho_tail k59_264962_1 1449355.JQNR01000006_gene2143 0.000138 52.8 2D784@1|root,32TNH@2|Bacteria,2GRDQ@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_198389_1 1234888.K0A2J2_9VIRU 1.48e-39 148.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_264963_1 1692250.A0A0K1RLR1_9CIRC 8.32e-128 372.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_214631_1 1692244.A0A0K1RLR5_9CIRC 1.21e-63 204.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_232083_2 908937.Prede_1324 8.31e-14 78.6 COG0162@1|root,COG0162@2|Bacteria,4NF19@976|Bacteroidetes,2FN0B@200643|Bacteroidia 976|Bacteroidetes J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b k59_58372_1 1234888.K0A2J2_9VIRU 1.86e-37 140.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_224276_1 1116369.KB890024_gene4323 1.18e-44 164.0 COG5108@1|root,COG5108@2|Bacteria,1PIWB@1224|Proteobacteria,2U1JR@28211|Alphaproteobacteria,43NYT@69277|Phyllobacteriaceae 28211|Alphaproteobacteria K DNA-dependent RNA polymerase - - - - - - - - - - - - RNA_pol,RPOL_N k59_216053_1 1463858.JOHR01000028_gene23 5.39e-15 79.7 29M5Z@1|root,3083E@2|Bacteria,2IKVT@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_8741_3 673376.F2VHW2_9CAUD 1.66e-26 99.8 4QCCA@10239|Viruses,4QY28@35237|dsDNA viruses no RNA stage,4QU0Q@28883|Caudovirales,4QNA0@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_199442_1 1609634.A0A0C5AFV4_9VIRU 5.84e-41 152.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_224288_1 1121479.AUBS01000027_gene427 3.36e-06 55.1 COG5434@1|root,COG5434@2|Bacteria,1MVBW@1224|Proteobacteria,2TVNM@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Pectate lyase superfamily protein - - - - - - - - - - - - Beta_helix,Pectate_lyase_3 k59_257533_1 1121459.AQXE01000001_gene2749 3.07e-30 124.0 28IA2@1|root,2Z8CQ@2|Bacteria,1PQM2@1224|Proteobacteria,42Y9U@68525|delta/epsilon subdivisions,2WTUC@28221|Deltaproteobacteria,2MARZ@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_249212_1 882083.SacmaDRAFT_4134 3.6e-49 172.0 COG0863@1|root,COG0863@2|Bacteria,2I9DJ@201174|Actinobacteria 201174|Actinobacteria L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.113,2.1.1.72 ko:K00571,ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_437_2 1392540.P256_00728 9.31e-43 149.0 COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,1SQ0T@1236|Gammaproteobacteria,3NSW6@468|Moraxellaceae 1236|Gammaproteobacteria L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_232628_1 1122931.AUAE01000008_gene4048 1.18e-17 92.8 COG0305@1|root,COG0305@2|Bacteria,4NF8P@976|Bacteroidetes,2FNFH@200643|Bacteroidia,231UH@171551|Porphyromonadaceae 976|Bacteroidetes L DnaB-like helicase N terminal domain - - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_232628_2 423476.A3F629_9CAUD 6.74e-45 155.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_133179_2 457398.HMPREF0326_01490 1.93e-77 243.0 COG0338@1|root,COG0338@2|Bacteria,1P85S@1224|Proteobacteria,42MJQ@68525|delta/epsilon subdivisions,2WM98@28221|Deltaproteobacteria,2MB81@213115|Desulfovibrionales 28221|Deltaproteobacteria L D12 class N6 adenine-specific DNA methyltransferase - - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12,Peptidase_S78_2 k59_133179_4 657309.BXY_43040 5.86e-09 57.0 COG1226@1|root,COG1226@2|Bacteria,4NWXV@976|Bacteroidetes,2FTXS@200643|Bacteroidia,4ARYW@815|Bacteroidaceae 976|Bacteroidetes P RyR domain - - - - - - - - - - - - RyR k59_240895_1 1500301.JQMF01000006_gene1755 3.51e-135 407.0 28MSK@1|root,2ZB0X@2|Bacteria,1R7CY@1224|Proteobacteria,2U2MY@28211|Alphaproteobacteria,4BJ92@82115|Rhizobiaceae 28211|Alphaproteobacteria S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_208455_3 1045858.Bint_1533 7.83e-121 371.0 COG5511@1|root,COG5511@2|Bacteria 2|Bacteria F Phage portal protein, lambda family JD73_18735 - - - - - - - - - - - Phage_portal_2 k59_109086_1 691966.D4P742_9CAUD 2.01e-16 81.3 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_241757_1 1234888.K0A2J2_9VIRU 5.25e-33 127.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_1602_2 521460.Athe_2445 4.39e-11 64.7 COG4570@1|root,COG4570@2|Bacteria,1UDK7@1239|Firmicutes,24T1T@186801|Clostridia,42INU@68295|Thermoanaerobacterales 186801|Clostridia L PFAM endodeoxyribonuclease RusA - - 3.1.22.4 ko:K01160 - - - - ko00000,ko01000,ko03400 - - - RusA k59_1602_4 887929.HMP0721_0482 2.52e-27 126.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia,25UTU@186806|Eubacteriaceae 186801|Clostridia L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_1602_15 1211115.ALIQ01000188_gene637 0.000381 45.4 2E46I@1|root,32Z2G@2|Bacteria,1N9GR@1224|Proteobacteria,2UFE5@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_250030_1 1492922.GY26_12325 8.13e-07 60.8 COG4675@1|root,COG4675@2|Bacteria,1RESM@1224|Proteobacteria,1S7DU@1236|Gammaproteobacteria 1236|Gammaproteobacteria S tail collar domain protein - - - - - - - - - - - - DUF3751 k59_9449_1 2880.D7FM14 2.69e-05 53.5 COG0749@1|root,KOG0950@2759|Eukaryota 2759|Eukaryota L plastid DNA replication POLQ GO:0000018,GO:0000724,GO:0000725,GO:0000726,GO:0002200,GO:0002376,GO:0002377,GO:0002440,GO:0002520,GO:0002566,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003684,GO:0003824,GO:0003887,GO:0004386,GO:0004518,GO:0004527,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006282,GO:0006284,GO:0006289,GO:0006302,GO:0006303,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007275,GO:0008094,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009314,GO:0009416,GO:0009628,GO:0009639,GO:0009640,GO:0009653,GO:0009791,GO:0009888,GO:0009892,GO:0009933,GO:0009987,GO:0010468,GO:0010564,GO:0010569,GO:0010605,GO:0016043,GO:0016445,GO:0016446,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016829,GO:0016835,GO:0016887,GO:0017111,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031324,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0036297,GO:0042623,GO:0042802,GO:0043142,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0045738,GO:0045910,GO:0045934,GO:0046483,GO:0048507,GO:0048519,GO:0048523,GO:0048532,GO:0048583,GO:0048585,GO:0048731,GO:0048856,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051239,GO:0051259,GO:0051260,GO:0051301,GO:0051575,GO:0051716,GO:0051726,GO:0060255,GO:0065003,GO:0065007,GO:0070013,GO:0071704,GO:0071840,GO:0071897,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0090305,GO:0097159,GO:0097681,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1901987,GO:1902749,GO:1990067,GO:2000011,GO:2000026,GO:2000042,GO:2000779,GO:2000780,GO:2001020,GO:2001021 2.7.7.7 ko:K02349 - - - - ko00000,ko01000,ko03400 - - - DEAD,DNA_pol_A,Helicase_C k59_183660_1 1000565.METUNv1_01729 1.56e-53 183.0 COG0270@1|root,COG0270@2|Bacteria,1MV9H@1224|Proteobacteria,2VIFH@28216|Betaproteobacteria,2KX72@206389|Rhodocyclales 206389|Rhodocyclales H C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_117603_1 1122197.ATWI01000011_gene460 1.41e-62 206.0 COG0433@1|root,COG0433@2|Bacteria,1QTVP@1224|Proteobacteria,1T1IQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Zonular occludens toxin (Zot) - - - ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko02042 - - - Zot k59_167307_1 1003195.SCAT_0615 1.98e-53 178.0 28MC2@1|root,2ZAQD@2|Bacteria,2IKMZ@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_150872_12 1477404.A0A023NGM3_9CAUD 9.55e-208 583.0 4QBMV@10239|Viruses,4QUU6@35237|dsDNA viruses no RNA stage,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_150872_15 490913.C4NTA1_9CAUD 7.02e-178 508.0 4QAR1@10239|Viruses,4QUNA@35237|dsDNA viruses no RNA stage,4QPJE@28883|Caudovirales,4QNDS@10744|Podoviridae 10744|Podoviridae S ATPase activity - - - - - - - - - - - - - k59_34722_2 1168281.I3PUX1_9CAUD 4.88e-07 55.5 4QBFN@10239|Viruses,4QXWN@35237|dsDNA viruses no RNA stage,4QPTW@28883|Caudovirales,4QNPZ@10744|Podoviridae 10744|Podoviridae S Phage stabilisation protein - - - - - - - - - - - - - k59_59384_1 1220717.L7TP31_9VIRU 3.63e-34 128.0 4QC2G@10239|Viruses 10239|Viruses S Ribonucleotide reductase, small chain - - - - - - - - - - - - - k59_26569_1 1379725.S5SYG4_9CIRC 9.26e-17 82.4 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_134301_1 1123312.KB904575_gene69 2.87e-13 75.1 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,4H9Z7@91061|Bacilli 91061|Bacilli L DNA polymerase polA_2 - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_2906_1 195253.Syn6312_3031 4.58e-42 144.0 2FADK@1|root,342MY@2|Bacteria,1GES1@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - k59_18666_1 765420.OSCT_3100 1.49e-08 61.6 COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,2G854@200795|Chloroflexi 200795|Chloroflexi M Domain of unknown function DUF11 - - - - - - - - - - - - DUF11 k59_93507_4 1279017.AQYJ01000026_gene8 5.35e-43 149.0 2918W@1|root,2ZNW0@2|Bacteria,1PBHF@1224|Proteobacteria,1SUWI@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_10494_3 1379715.S5TMW6_9CIRC 8.84e-38 139.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_60283_1 1348908.KI518589_gene2550 3.84e-26 113.0 COG0863@1|root,COG0863@2|Bacteria,1TR56@1239|Firmicutes,4HHJ7@91061|Bacilli,1ZKIN@1386|Bacillus 91061|Bacilli L DNA methylase - - 2.1.1.113 ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_192757_3 145579.CAPSD_BPPHM 4.94e-142 427.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_192757_5 1385658.U5KNR1_9VIRU 1.21e-41 151.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_93513_1 455632.SGR_6598 4.16e-05 53.5 COG3250@1|root,COG3250@2|Bacteria,2GMAT@201174|Actinobacteria,41ADZ@629295|Streptomyces griseus group 201174|Actinobacteria G PA14 - - - - - - - - - - - - Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Laminin_G_3,PA14 k59_218801_1 438753.AZC_3598 2.49e-70 229.0 COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1QT52@1224|Proteobacteria,2TVNI@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Toprim-like - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - DnaB_C,Toprim_2 k59_119224_1 111105.HR09_00645 2.8e-07 52.4 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,2FM8X@200643|Bacteroidia,22WNP@171551|Porphyromonadaceae 976|Bacteroidetes L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_250917_1 1385658.U5KNR1_9VIRU 9.28e-43 152.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_152135_3 1517681.HW45_02700 2.68e-42 172.0 COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,1QZAD@1224|Proteobacteria,1RYP3@1236|Gammaproteobacteria 1236|Gammaproteobacteria D nuclear chromosome segregation - - - - - - - - - - - - - k59_159813_1 742925.D4N3R4_9CIRC 5.73e-22 101.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_184872_1 1234888.K0A2J2_9VIRU 8.91e-40 148.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_68828_1 1123508.JH636444_gene5347 4.64e-06 53.9 2DQ9V@1|root,335IH@2|Bacteria 2|Bacteria - - - - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - - k59_210371_1 1234888.K0A2J2_9VIRU 1.6e-59 201.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_186060_2 1618248.A0A0C5IB82_9CIRC 4.38e-27 107.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_251856_1 1121937.AUHJ01000007_gene1934 7.96e-51 167.0 2DICG@1|root,302RI@2|Bacteria,1PVSB@1224|Proteobacteria,1STCY@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_85745_1 649639.Bcell_2721 4.11e-55 196.0 COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,1UHQM@1239|Firmicutes,4HGW7@91061|Bacilli,1ZBWW@1386|Bacillus 91061|Bacilli D phage tail tape measure protein - - - - - - - - - - - - Peptidase_M23,PhageMin_Tail,SLT k59_160918_2 1234888.K0A2J2_9VIRU 1.75e-148 437.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_53753_2 1379713.S5SYD9_9CIRC 1.52e-13 75.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_78327_2 1051675.G0YQC0_9CAUD 7.16e-26 106.0 4QEWC@10239|Viruses,4QYMK@35237|dsDNA viruses no RNA stage,4QUH4@28883|Caudovirales,4QP0K@10744|Podoviridae 10744|Podoviridae S signal transduction - - - - - - - - - - - - - k59_94449_1 1144310.PMI07_002360 0.00026 49.3 2DPZ1@1|root,3340X@2|Bacteria,1R2EE@1224|Proteobacteria,2TZIB@28211|Alphaproteobacteria,4BP2Q@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_111748_4 593117.TGAM_0130 3.95e-55 188.0 COG0468@1|root,arCOG00415@2157|Archaea,2XT80@28890|Euryarchaeota,242UY@183968|Thermococci 183968|Thermococci L Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules radA GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - ko:K04483 - - - - ko00000,ko03400 - - - HHH_5,Intein_splicing,LAGLIDADG_3,Rad51 k59_145312_1 56107.Cylst_1960 2.16e-43 152.0 COG5655@1|root,COG5655@2|Bacteria,1GE7K@1117|Cyanobacteria,1HT1G@1161|Nostocales 1117|Cyanobacteria L Replication protein - - - - - - - - - - - - Rep_1 k59_136472_4 1379714.S5TND6_9CIRC 2.36e-07 55.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_102996_3 1234888.K0A2J2_9VIRU 7.93e-182 525.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_102996_4 1234888.K0A2R8_9VIRU 1.85e-41 150.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_4339_2 500637.PROVRUST_04522 1.63e-13 72.4 COG1896@1|root,COG1896@2|Bacteria,1PP1F@1224|Proteobacteria,1TC5Y@1236|Gammaproteobacteria,3ZAD7@586|Providencia 1236|Gammaproteobacteria S Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates - - - - - - - - - - - - - k59_153425_2 562743.JH976434_gene1043 2.28e-10 64.3 28PQ6@1|root,2ZCCB@2|Bacteria,1V1NK@1239|Firmicutes,4HGG6@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k59_103136_1 1618241.A0A0C5I2I4_9CIRC 2.66e-07 57.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_19763_1 1492922.GY26_15975 9.03e-29 120.0 COG1196@1|root,COG1511@1|root,COG1196@2|Bacteria,COG1511@2|Bacteria 2|Bacteria Q domain protein - - - ko:K02666 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - DUF349 k59_227851_1 1506583.JQJY01000003_gene3390 1.44e-10 67.4 COG1196@1|root,COG1511@1|root,COG1196@2|Bacteria,COG1511@2|Bacteria 2|Bacteria Q domain protein yjeP - - ko:K01421,ko:K02004,ko:K02316,ko:K05802,ko:K10953,ko:K12684,ko:K22051 ko03030,ko05110,map03030,map05110 M00258 - - ko00000,ko00001,ko00002,ko01000,ko02000,ko02042,ko02044,ko03032 1.A.23.1.1,1.A.23.1.2,1.A.23.1.3,1.B.12.4,3.A.1 - - AAA_15,MS_channel,MscS_TM,MscS_porin k59_186217_2 296591.Bpro_3746 1.44e-21 90.1 2EPH2@1|root,33H3P@2|Bacteria,1NBTX@1224|Proteobacteria,2VY22@28216|Betaproteobacteria 28216|Betaproteobacteria S protein B3ORF37 Bacteriophage B3 gi 33338631 gb AAQ13955.1 - - - - - - - - - - - - - k59_186217_3 1131814.JAFO01000001_gene1465 3e-63 210.0 28H88@1|root,2Z7K7@2|Bacteria,1R5AY@1224|Proteobacteria,2TSW5@28211|Alphaproteobacteria 28211|Alphaproteobacteria S to capsid protein Bacteriophage B3 gi 33338632 gb AAQ13956.1 - - - - - - - - - - - - - k59_186217_11 1123278.KB893466_gene2015 6.59e-32 144.0 COG3941@1|root,COG3941@2|Bacteria,4NS30@976|Bacteroidetes,47XQ2@768503|Cytophagia 976|Bacteroidetes S tape measure - - - - - - - - - - - - - k59_179102_4 1385658.U5KPZ6_9VIRU 1.57e-180 526.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_37764_3 1563661.A0A097PBD1_9CAUD 4.91e-68 215.0 4QFP7@10239|Viruses,4QSRU@28883|Caudovirales,4QNWE@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - - - - - - - - - - - - - k59_187727_1 1205681.CALW02000016_gene1219 1.32e-24 107.0 28MVD@1|root,2ZB2Y@2|Bacteria,1R8NK@1224|Proteobacteria,2U265@28211|Alphaproteobacteria,48T1V@772|Bartonellaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF4043) - - - - - - - - - - - - DUF4043 k59_62379_2 1121921.KB898707_gene976 4.4e-135 422.0 COG3170@1|root,COG3170@2|Bacteria,1N4R0@1224|Proteobacteria,1RY0B@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU Tfp pilus assembly protein FimV - - - - - - - - - - - - - k59_30500_1 572546.Arcpr_0811 0.000271 49.3 COG0464@1|root,arCOG03154@1|root,arCOG01308@2157|Archaea,arCOG03154@2157|Archaea,2XSYR@28890|Euryarchaeota,245UG@183980|Archaeoglobi 183980|Archaeoglobi O AAA family ATPase, CDC48 subfamily - - - ko:K13525 ko04141,ko05134,map04141,map05134 M00400,M00403 - - ko00000,ko00001,ko00002,ko03019,ko04131,ko04147 3.A.16.1 - - AAA,CDC48_2,CDC48_N,Vps4_C k59_13008_1 1234888.K0A2J2_9VIRU 6.93e-57 195.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_104450_2 1414739.W6ATC3_9CAUD 5.55e-45 151.0 4QF67@10239|Viruses,4QY5V@35237|dsDNA viruses no RNA stage,4QRT2@28883|Caudovirales,4QM4P@10699|Siphoviridae 10699|Siphoviridae S exonuclease activity - - - - - - - - - - - - - k59_62384_2 1458851.X2KMA0_9CAUD 4.14e-23 92.4 4QAQV@10239|Viruses,4QUPK@35237|dsDNA viruses no RNA stage,4QPCB@28883|Caudovirales,4QKM5@10699|Siphoviridae 10699|Siphoviridae S sequence-specific DNA binding - - - - - - - - - - - - - k59_55163_3 1234888.K0A2J2_9VIRU 2.72e-79 253.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_171468_1 1123269.NX02_21995 1.06e-19 93.6 COG0553@1|root,COG0553@2|Bacteria,1R7CK@1224|Proteobacteria,2U228@28211|Alphaproteobacteria,2KA8N@204457|Sphingomonadales 204457|Sphingomonadales KL DEAD-like helicases superfamily - - - - - - - - - - - - - k59_195273_1 1385935.N836_03570 2.22e-72 230.0 COG4373@1|root,COG4373@2|Bacteria,1GBSR@1117|Cyanobacteria,1HEY2@1150|Oscillatoriales 1117|Cyanobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_147099_2 1283300.ATXB01000002_gene2532 2.83e-21 90.5 COG3772@1|root,COG3772@2|Bacteria,1N0ZQ@1224|Proteobacteria,1S9AE@1236|Gammaproteobacteria 1236|Gammaproteobacteria S lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_163580_1 1204537.K4JRJ4_9CAUD 3.68e-78 247.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - GO:0005575,GO:0019012,GO:0019028,GO:0032991,GO:0044423,GO:0046806 - - - - - - - - - - - k59_115068_1 1986029.Q9MBM8_9VIRU 5.08e-16 79.3 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_14096_1 1385658.U5KNR1_9VIRU 1.14e-42 153.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_123183_1 1095747.HMPREF1049_1841 0.00014 46.2 COG0553@1|root,COG0553@2|Bacteria,3791F@32066|Fusobacteria 32066|Fusobacteria L SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,SNF2_N k59_123183_3 1033743.CAES01000020_gene3156 7.91e-06 56.2 COG2887@1|root,COG2887@2|Bacteria,1TPIC@1239|Firmicutes,4HCNN@91061|Bacilli,26S2A@186822|Paenibacillaceae 91061|Bacilli L Protein of unknown function (DUF2800) - - - - - - - - - - - - DUF2800 k59_123183_6 1216932.CM240_0655 5.34e-22 104.0 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,2487V@186801|Clostridia,36EDD@31979|Clostridiaceae 186801|Clostridia L DNA polymerase - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_189445_2 875328.JDM601_3424 3.46e-06 57.8 COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,232NN@1762|Mycobacteriaceae 201174|Actinobacteria IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II fadD3_2 - 6.2.1.41 ko:K00666,ko:K18687 ko00984,ko01100,ko01120,map00984,map01100,map01120 - R10769 RC00004,RC00014 ko00000,ko00001,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k59_22216_1 279383.Q5DN23_9CAUD 4.93e-17 93.2 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_105779_1 1342299.Z947_2214 2.1e-19 86.7 2ARIQ@1|root,31GV5@2|Bacteria,1RM5P@1224|Proteobacteria,2U9D1@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Antirestriction protein (ArdA) - - - - - - - - - - - - ArdA k59_230359_4 1124982.MSI_23280 1.17e-24 101.0 COG4712@1|root,COG4712@2|Bacteria 2|Bacteria S DNA recombination - - - - - - - - - - - - Rad52_Rad22 k59_96923_1 557598.LHK_01542 5.64e-76 240.0 28HXV@1|root,2Z83C@2|Bacteria,1PJBP@1224|Proteobacteria,2VZV5@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_205980_1 649747.HMPREF0083_01035 9e-61 201.0 COG0270@1|root,COG0270@2|Bacteria,1TPNE@1239|Firmicutes,4HHQR@91061|Bacilli 91061|Bacilli H C-5 cytosine-specific DNA methylase - - - - - - - - - - - - DNA_methylase k59_246121_1 1121861.KB899916_gene1642 1.16e-26 106.0 2DNV9@1|root,32ZB3@2|Bacteria,1R2IQ@1224|Proteobacteria,2TZKJ@28211|Alphaproteobacteria,2JZ35@204441|Rhodospirillales 2|Bacteria - - - - - - - - - - - - - - - k59_148620_4 398578.Daci_3225 4.64e-15 71.2 2EI4V@1|root,33BW7@2|Bacteria,1NN3Z@1224|Proteobacteria 1224|Proteobacteria S Protein of unknwon function (DUF3310) - - - - - - - - - - - - DUF3310 k59_223604_2 1457393.AZ09_10555 5.94e-27 112.0 2CJW6@1|root,32SAX@2|Bacteria,1N3WF@1224|Proteobacteria,2USGV@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_163699_2 12348.Q8SDH3_BPLLH 3.27e-09 62.0 4QAX8@10239|Viruses,4QVB1@35237|dsDNA viruses no RNA stage,4QPHH@28883|Caudovirales,4QKTJ@10699|Siphoviridae 10699|Siphoviridae S calcium ion binding - - - - - - - - - - - - - k59_131519_1 1223544.GSI01S_01_03130 2.52e-11 72.0 COG5283@1|root,COG5283@2|Bacteria,2I92I@201174|Actinobacteria,4GCJR@85026|Gordoniaceae 201174|Actinobacteria M Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_39102_2 556269.ACDQ01000006_gene1583 2.33e-34 130.0 28NGF@1|root,2Z9HT@2|Bacteria,1R9QF@1224|Proteobacteria,2VPSU@28216|Betaproteobacteria,47599@75682|Oxalobacteraceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_7710_2 998088.B565_2073 7.24e-21 91.3 28KZZ@1|root,2ZAF4@2|Bacteria,1R6SC@1224|Proteobacteria,1RR2K@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF1367) - - - - - - - - - - - - DUF1367 k59_140935_1 655097.C8ZKI5_9CAUD 7.32e-50 167.0 4QGM6@10239|Viruses,4QYNV@35237|dsDNA viruses no RNA stage,4QRH4@28883|Caudovirales,4QP0P@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_40142_5 91464.S7335_1907 4.01e-13 72.8 COG1943@1|root,COG1943@2|Bacteria,1G9J6@1117|Cyanobacteria,1H3MP@1129|Synechococcus 1117|Cyanobacteria L Sulfotransferase family - - - - - - - - - - - - Sulfotransfer_2 k59_164942_1 444860.E3SJ76_9CAUD 2.96e-66 213.0 4QCFA@10239|Viruses,4QUPF@35237|dsDNA viruses no RNA stage,4QQD7@28883|Caudovirales,4QIYX@10662|Myoviridae 10662|Myoviridae S coenzyme binding - - - - - - - - - - - - - k59_164942_2 243233.MCA1513 2.77e-19 84.3 COG1442@1|root,COG1442@2|Bacteria,1QH4S@1224|Proteobacteria 1224|Proteobacteria M glycosyl transferase family 8 - - - - - - - - - - - - Glyco_transf_8 k59_264885_5 2003327.CAPSD_BPCHP 1.52e-47 181.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_15396_1 1477404.A0A023NG67_9CAUD 2.23e-60 197.0 4QDXM@10239|Viruses,4QWIX@35237|dsDNA viruses no RNA stage,4QQF6@28883|Caudovirales,4QNXH@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_64705_1 1200557.JHWV01000006_gene1732 9.47e-54 185.0 COG5362@1|root,COG5362@2|Bacteria,1UI9S@1239|Firmicutes 1239|Firmicutes S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_255824_1 490913.C4NTE0_9CAUD 5.67e-26 112.0 4QAXA@10239|Viruses,4QYJI@35237|dsDNA viruses no RNA stage,4QQ1A@28883|Caudovirales,4QNU7@10744|Podoviridae 10744|Podoviridae S metallopeptidase activity - - - - - - - - - - - - - k59_106800_2 942016.E9NIH0_9CAUD 2.2e-111 350.0 4QGA5@10239|Viruses,4QURD@35237|dsDNA viruses no RNA stage,4QT9N@28883|Caudovirales,4QP47@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_231719_1 1173025.GEI7407_2517 1.37e-66 216.0 COG0592@1|root,COG0592@2|Bacteria,1FZV5@1117|Cyanobacteria,1H7IH@1150|Oscillatoriales 1117|Cyanobacteria L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 k59_40330_1 77635.BISU_0470 6.22e-14 80.1 28MKK@1|root,2ZAWR@2|Bacteria,2IS2W@201174|Actinobacteria,4D1DD@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - RNA_helicase,Viral_Rep k59_157416_1 1692261.A0A0K1RLL5_9CIRC 2.41e-21 100.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_238953_2 1127673.GLIP_3386 3.01e-14 72.8 2AD08@1|root,312N7@2|Bacteria,1NDC4@1224|Proteobacteria 1224|Proteobacteria S Holin of 3TMs, for gene-transfer release - - - - - - - - - - - - GTA_holin_3TM k59_82162_2 1122176.KB903532_gene2562 3.75e-09 62.8 COG2931@1|root,COG5295@1|root,COG2931@2|Bacteria,COG5295@2|Bacteria,4NF3S@976|Bacteroidetes,1ISQ8@117747|Sphingobacteriia 976|Bacteroidetes UW domain, Protein - - - - - - - - - - - - Collagen,Peptidase_S74 k59_15423_1 1121937.AUHJ01000007_gene1914 2.7e-46 161.0 COG0582@1|root,COG0582@2|Bacteria,1QB64@1224|Proteobacteria,1RY8S@1236|Gammaproteobacteria,468CF@72275|Alteromonadaceae 1236|Gammaproteobacteria L Phage integrase family - - - - - - - - - - - - Arm-DNA-bind_1,Phage_int_SAM_4,Phage_integrase k59_255840_2 1158150.KB906242_gene214 2.15e-77 243.0 COG0258@1|root,COG0258@2|Bacteria,1MYSI@1224|Proteobacteria,1SQ55@1236|Gammaproteobacteria 1236|Gammaproteobacteria L 5'-3' exonuclease, N-terminal resolvase-like domain - - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc_N k59_207118_1 1117943.SFHH103_03916 3.14e-28 118.0 COG1961@1|root,COG1961@2|Bacteria,1N6DV@1224|Proteobacteria,2TVBV@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Recombinase - - - - - - - - - - - - Recombinase,Resolvase,Zn_ribbon_recom k59_257273_1 1379724.S5T6B0_9CIRC 4.67e-28 113.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_215779_5 1226994.AMZB01000137_gene5401 2.69e-20 91.7 28PTM@1|root,2ZCEU@2|Bacteria,1R5DD@1224|Proteobacteria 1224|Proteobacteria S Family of unknown function (DUF5309) - - - - - - - - - - - - DUF5309 k59_74779_6 644107.SL1157_1635 2.64e-41 154.0 COG2404@1|root,COG2404@2|Bacteria,1PKY9@1224|Proteobacteria,2V2FR@28211|Alphaproteobacteria,4NDK2@97050|Ruegeria 28211|Alphaproteobacteria S hydrolase activity, acting on ester bonds - - - - - - - - - - - - - k59_33376_3 68570.DC74_2981 1.01e-07 61.6 COG1475@1|root,COG1475@2|Bacteria,2IF26@201174|Actinobacteria 201174|Actinobacteria K ParB-like nuclease domain - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_182587_1 1692244.A0A0K1RLR5_9CIRC 1.11e-95 290.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_257282_1 1385658.U5KNR1_9VIRU 8.37e-39 141.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_190874_1 1316936.K678_00265 2.55e-131 401.0 28HPK@1|root,2Z7XJ@2|Bacteria,1NBHR@1224|Proteobacteria,2TT3N@28211|Alphaproteobacteria,2JQ8P@204441|Rhodospirillales 204441|Rhodospirillales S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_190874_3 521000.PROVRETT_05505 7.7e-181 523.0 COG0507@1|root,COG0507@2|Bacteria,1R1AT@1224|Proteobacteria,1RS66@1236|Gammaproteobacteria,3Z9Q5@586|Providencia 1236|Gammaproteobacteria L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD - - - - - - - - - - - - - k59_190874_4 1073754.G0ZND3_9VIRU 2.25e-64 202.0 4QB6U@10239|Viruses 10239|Viruses S Terminase small subunit - - - - - - - - - - - - - k59_224043_1 861208.AGROH133_06202 7.07e-73 237.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2TSDW@28211|Alphaproteobacteria,4BCQ8@82115|Rhizobiaceae 28211|Alphaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_74787_2 296591.Bpro_3742 2.39e-13 65.5 2D1MV@1|root,32TAZ@2|Bacteria,1N45A@1224|Proteobacteria,2VX6Y@28216|Betaproteobacteria,4AIVH@80864|Comamonadaceae 28216|Betaproteobacteria S Phage protein (N4 Gp49/phage Sf6 gene 66) family - - - - - - - - - - - - Phage_gp49_66 k59_232413_2 1122201.AUAZ01000021_gene3143 7.43e-20 85.5 COG3108@1|root,COG3108@2|Bacteria,1RICX@1224|Proteobacteria,1S6D5@1236|Gammaproteobacteria 1236|Gammaproteobacteria S peptidase M15 - - - ko:K17733 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M15_4 k59_215781_2 1692257.A0A0K1RL39_9CIRC 5.76e-93 285.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_149343_2 1788454.A0A190WHE4_9CIRC 6.97e-39 141.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_157798_1 398578.Daci_1946 6.05e-11 69.7 28PTM@1|root,2ZCEU@2|Bacteria,1R5DD@1224|Proteobacteria,2W259@28216|Betaproteobacteria 28216|Betaproteobacteria S Family of unknown function (DUF5309) - - - - - - - - - - - - DUF5309 k59_124705_2 1532557.JL37_11060 2.49e-16 77.4 2BA7A@1|root,323MC@2|Bacteria,1RIHY@1224|Proteobacteria,2VTIA@28216|Betaproteobacteria,3T7MZ@506|Alcaligenaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_99761_1 1477404.A0A023NG15_9CAUD 1.09e-11 61.2 4QH0J@10239|Viruses,4QW6C@35237|dsDNA viruses no RNA stage,4QST9@28883|Caudovirales,4QNZ3@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_246163_1 1117943.SFHH103_00150 1.17e-07 58.5 2DPZ1@1|root,3340X@2|Bacteria,1R2EE@1224|Proteobacteria,2TZIB@28211|Alphaproteobacteria,4BP2Q@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_131551_3 1455626.W5ZKV0_9CIRC 7.43e-26 111.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_80861_2 1026955.F5B441_9CAUD 3.57e-33 121.0 4QAJX@10239|Viruses,4QUZ8@35237|dsDNA viruses no RNA stage,4QPK4@28883|Caudovirales,4QHZF@10662|Myoviridae 10662|Myoviridae S Pfam:DUF5051 - - - - - - - - - - - - - k59_32346_3 926560.KE387029_gene76 1.66e-23 94.7 COG1694@1|root,COG1694@2|Bacteria 2|Bacteria FG Mazg nucleotide pyrophosphohydrolase - - - - - - - - - - - - MazG k59_223789_1 1121918.ARWE01000001_gene767 1.68e-84 261.0 COG4397@1|root,COG4397@2|Bacteria,1MWX8@1224|Proteobacteria,42QUQ@68525|delta/epsilon subdivisions,2WN4N@28221|Deltaproteobacteria,43VF0@69541|Desulfuromonadales 28221|Deltaproteobacteria S Mu-like prophage major head subunit gpT - - - - - - - - - - - - Mu-like_gpT k59_223789_2 1041159.AZUW01000001_gene3268 6.54e-59 187.0 2AD4I@1|root,300N2@2|Bacteria,1PR6C@1224|Proteobacteria,2V3HE@28211|Alphaproteobacteria,4BKMT@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_123455_6 522306.CAP2UW1_2243 1.79e-07 62.8 COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,2VJEX@28216|Betaproteobacteria 28216|Betaproteobacteria NU Neisseria PilC beta-propeller domain pilY1 - - ko:K02674 - - - - ko00000,ko02035,ko02044 - - - Neisseria_PilC k59_123455_12 500637.PROVRUST_05413 1.18e-23 93.6 COG3179@1|root,COG3179@2|Bacteria,1RE8K@1224|Proteobacteria,1S4U8@1236|Gammaproteobacteria,3Z9BP@586|Providencia 1236|Gammaproteobacteria S D-alanyl-D-alanine carboxypeptidase - - - - - - - - - - - - Peptidase_M15_4 k59_163878_1 693746.OBV_28450 1.93e-11 71.2 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia,2N6XB@216572|Oscillospiraceae 186801|Clostridia L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_22521_1 145579.CAPSD_BPPHM 6.5e-97 300.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_115361_1 1788454.A0A190WHE4_9CIRC 2.06e-13 69.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_56764_3 1123257.AUFV01000013_gene2785 9.62e-48 166.0 COG0863@1|root,COG0863@2|Bacteria,1PCSE@1224|Proteobacteria,1SARI@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_189884_1 1122147.AUEH01000027_gene2759 6.44e-38 145.0 COG3378@1|root,COG4983@1|root,COG3378@2|Bacteria,COG4983@2|Bacteria,1TQP9@1239|Firmicutes,4HBTB@91061|Bacilli,3F3UD@33958|Lactobacillaceae 91061|Bacilli S Phage plasmid primase, P4 - - - ko:K06919 - - - - ko00000 - - - D5_N,Pox_D5,PriCT_1,Prim-Pol k59_39259_1 1414739.W6AT00_9CAUD 2.57e-23 104.0 4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - GO:0008150,GO:0044403,GO:0044409,GO:0044411,GO:0044419,GO:0051701,GO:0051704,GO:0051828,GO:0051830,GO:0085027 - - - - - - - - - - - k59_213054_1 1267535.KB906767_gene2463 1.44e-15 81.3 COG1783@1|root,COG1783@2|Bacteria,3Y64R@57723|Acidobacteria 57723|Acidobacteria S phage Terminase large subunit - - - - - - - - - - - - - k59_156453_1 1986029.Q9MBM3_9VIRU 4.88e-20 92.4 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_230636_3 1170562.Cal6303_3610 4.91e-67 216.0 COG0675@1|root,COG0675@2|Bacteria,1G01E@1117|Cyanobacteria,1HMDP@1161|Nostocales 1117|Cyanobacteria L TIGRFAM transposase, IS605 OrfB family, central region - - - ko:K07496 - - - - ko00000 - - - HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon k59_254762_1 655097.C8ZKI1_9CAUD 1.72e-23 103.0 4QF3C@10239|Viruses,4QWIA@35237|dsDNA viruses no RNA stage,4QU4U@28883|Caudovirales,4QNNQ@10744|Podoviridae 10744|Podoviridae S host cell wall - - - - - - - - - - - - - k59_22623_2 1406780.U5PWH9_9CAUD 1.8e-07 54.3 4QBY0@10239|Viruses,4QW35@35237|dsDNA viruses no RNA stage,4QQ4Q@28883|Caudovirales,4QNNN@10744|Podoviridae 10744|Podoviridae S UvrD-like helicase C-terminal domain - - - - - - - - - - - - - k59_140121_1 1173028.ANKO01000032_gene1761 1.01e-51 169.0 COG1351@1|root,COG1351@2|Bacteria,1G1PU@1117|Cyanobacteria,1H8RR@1150|Oscillatoriales 1117|Cyanobacteria F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant thyX - 2.1.1.148 ko:K03465 ko00240,ko00670,ko01100,map00240,map00670,map01100 - R06613 RC00022,RC00332 ko00000,ko00001,ko01000 - - - HNH,Intein_splicing,Thy1 k59_32470_4 652103.Rpdx1_2982 1.07e-86 286.0 COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1QT50@1224|Proteobacteria,2TTND@28211|Alphaproteobacteria,3JW9V@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L TOPRIM - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - AAA_25,DnaB_C,Toprim_2,Toprim_4 k59_32470_5 948870.I7HJE3_9CAUD 0.000218 46.6 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QI32@10662|Myoviridae 10662|Myoviridae S DNA polymerase family A - - - - - - - - - - - - - k59_181076_2 511051.CSE_10850 1.37e-13 72.0 COG0817@1|root,COG0817@2|Bacteria 2|Bacteria L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group ruvC GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 ko:K01159 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvC k59_56967_1 31535.D4FUM0_BPD3 2.13e-12 67.8 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_56967_3 443152.MDG893_20574 3.02e-30 112.0 2CHRA@1|root,32S6D@2|Bacteria,1MZ8I@1224|Proteobacteria,1SHSQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage tail assembly chaperone, TAC - - - - - - - - - - - - Phage_TAC_13 k59_115607_1 1121033.AUCF01000008_gene5754 5.52e-39 140.0 COG0811@1|root,COG0811@2|Bacteria,1PPAP@1224|Proteobacteria 1224|Proteobacteria U MotA/TolQ/ExbB proton channel family MA20_09275 - - - - - - - - - - - MotA_ExbB k59_131783_1 1692257.A0A0K1RL39_9CIRC 1.69e-59 197.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_131783_2 1692242.A0A0K1RKZ2_9CIRC 1.62e-15 77.8 4QFEW@10239|Viruses,4QUKZ@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_39447_2 1414739.W6B351_9CAUD 3.2e-25 105.0 4QAQ9@10239|Viruses,4QUYQ@35237|dsDNA viruses no RNA stage,4QPTV@28883|Caudovirales,4QKRS@10699|Siphoviridae 10699|Siphoviridae S Putative phage tail protein - GO:0005575,GO:0008150,GO:0016032,GO:0018995,GO:0019012,GO:0019058,GO:0019062,GO:0022610,GO:0030430,GO:0033643,GO:0033646,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044403,GO:0044406,GO:0044419,GO:0044650,GO:0051704 - - - - - - - - - - - k59_81190_2 1788454.A0A190WHE4_9CIRC 4.62e-50 174.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_56977_2 392499.Swit_2129 5.14e-15 73.9 2EBAW@1|root,335BJ@2|Bacteria,1N90V@1224|Proteobacteria,2UIYS@28211|Alphaproteobacteria,2K4JF@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - DUF5051 k59_254877_1 1692255.A0A0K1RL52_9CIRC 3.61e-80 253.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_164130_3 1234888.K0A2J2_9VIRU 5.39e-106 332.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_181080_1 795666.MW7_2012 2.12e-12 74.3 COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,2VPZQ@28216|Betaproteobacteria,1K1QM@119060|Burkholderiaceae 28216|Betaproteobacteria L TIGRFAM phage SPO1 DNA polymerase-related protein dpo - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k59_181080_4 765765.I3UMF8_9CAUD 4.75e-18 89.0 4QBY0@10239|Viruses,4QW35@35237|dsDNA viruses no RNA stage,4QQ4Q@28883|Caudovirales,4QNAU@10699|Siphoviridae 10699|Siphoviridae S UvrD-like helicase C-terminal domain - - - - - - - - - - - - - k59_173537_1 1156919.QWC_12533 2.15e-49 172.0 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1NKZK@1224|Proteobacteria,2VM59@28216|Betaproteobacteria,3T7Q0@506|Alcaligenaceae 28216|Betaproteobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C k59_206321_1 1493511.A0A0E3FLK1_9CAUD 1.03e-114 347.0 4QAWG@10239|Viruses,4QPII@28883|Caudovirales,4QI76@10662|Myoviridae 10662|Myoviridae S DNA helicase activity - - - - - - - - - - - - - k59_22747_2 1122138.AQUZ01000143_gene7945 5.84e-09 62.4 COG1783@1|root,COG1783@2|Bacteria 2|Bacteria S DNA packaging - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_6 k59_164972_2 546275.FUSPEROL_02001 9.15e-29 108.0 COG3108@1|root,COG3108@2|Bacteria,37ATH@32066|Fusobacteria 32066|Fusobacteria S D-alanyl-D-alanine carboxypeptidase - - - - - - - - - - - - Peptidase_M15_4 k59_255678_1 7209.EFO25451.1 2.62e-06 52.4 2EWQP@1|root,2SYH6@2759|Eukaryota 2759|Eukaryota S RNA helicase - - - - - - - - - - - - RNA_helicase,Viral_Rep k59_23629_2 691965.D4P7E5_9CAUD 6.78e-28 106.0 4QEVD@10239|Viruses,4QW84@35237|dsDNA viruses no RNA stage,4QQSX@28883|Caudovirales,4QMU4@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_181763_1 306264.CUP0954 0.000255 51.6 2BSDU@1|root,32MFT@2|Bacteria,1Q39B@1224|Proteobacteria,42SUB@68525|delta/epsilon subdivisions 1224|Proteobacteria - - - - - - - - - - - - - - DUF3519 k59_255684_1 1121286.AUMT01000001_gene41 5.45e-61 204.0 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,4P9P1@976|Bacteroidetes,1IHFS@117743|Flavobacteriia,3ZU5R@59732|Chryseobacterium 976|Bacteroidetes S TIGRFAM Phage - - - - - - - - - - - - - k59_197755_1 1609634.A0A0C5AFV4_9VIRU 9.83e-49 170.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_57684_1 410359.Pcal_0356 3.44e-12 75.1 COG0419@1|root,arCOG00368@2157|Archaea,2XQHC@28889|Crenarchaeota 28889|Crenarchaeota L Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex rad50 - - ko:K03546 - - - - ko00000,ko03400 - - - AAA_15,AAA_23,Rad50_zn_hook,SMC_N,SbcCD_C k59_132626_1 1408304.JAHA01000019_gene2226 2.31e-45 157.0 COG0107@1|root,COG0107@2|Bacteria,1TP0W@1239|Firmicutes,24900@186801|Clostridia,4BWR2@830|Butyrivibrio 186801|Clostridia E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit hisF - - ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth k59_164985_1 1161935.H9D1D6_9CAUD 3.3e-43 151.0 4QFN8@10239|Viruses,4QYWE@35237|dsDNA viruses no RNA stage,4QS52@28883|Caudovirales,4QP1K@10744|Podoviridae 10744|Podoviridae S metal ion binding - - - - - - - - - - - - - k59_207002_3 1141106.CAIB01000118_gene947 3.01e-06 47.4 29R18@1|root,30C2C@2|Bacteria,1W3U4@1239|Firmicutes,4I259@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k59_207002_4 373994.Riv7116_5755 2.95e-16 75.5 COG1694@1|root,COG1694@2|Bacteria,1GA07@1117|Cyanobacteria 1117|Cyanobacteria S Pyrophosphatase - - - - - - - - - - - - MazG k59_57689_1 575540.Isop_2443 1.92e-44 164.0 COG1061@1|root,COG1061@2|Bacteria,2J0ES@203682|Planctomycetes 203682|Planctomycetes L COGs COG1061 DNA or RNA helicase of superfamily II - - - ko:K19789 - - - - ko00000,ko03400 - - - Helicase_C,ResIII k59_165187_2 1236504.HMPREF2132_01780 2.97e-14 71.6 COG1694@1|root,COG1694@2|Bacteria 2|Bacteria FG Mazg nucleotide pyrophosphohydrolase MA20_27270 - - - - - - - - - - - MazG k59_239054_1 720554.Clocl_1510 3.79e-11 69.7 COG3378@1|root,COG4983@1|root,COG3378@2|Bacteria,COG4983@2|Bacteria,1TQP9@1239|Firmicutes,24AY6@186801|Clostridia,3WHX7@541000|Ruminococcaceae 186801|Clostridia S Phage plasmid primase, P4 family - - - ko:K06919 - - - - ko00000 - - - D5_N,Pox_D5,PriCT_1,Prim-Pol k59_98056_1 1384065.JAGS01000001_gene752 6.16e-12 72.0 COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,247KM@186801|Clostridia,3WGRB@541000|Ruminococcaceae 186801|Clostridia D Belongs to the FtsK SpoIIIE SftA family spoIIIE - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma k59_265240_1 742918.D4N3P2_9CIRC 2.75e-12 73.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_90806_2 1618240.A0A0C5IMJ1_9CIRC 9.71e-148 421.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_199055_5 765698.Mesci_3835 1.24e-69 235.0 COG5323@1|root,COG5323@2|Bacteria,1R049@1224|Proteobacteria 1224|Proteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6 k59_199055_6 260827.Q6R6B4_9CAUD 2.56e-142 429.0 4QCM5@10239|Viruses,4QVZY@35237|dsDNA viruses no RNA stage,4QQFH@28883|Caudovirales,4QNDH@10744|Podoviridae 10744|Podoviridae S Bacteriophage head to tail connecting protein - GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019028,GO:0019058,GO:0019068,GO:0019072,GO:0019073,GO:0032991,GO:0044403,GO:0044419,GO:0044423,GO:0046798,GO:0051704 - - - - - - - - - - - k59_109_1 1234888.K0A2J2_9VIRU 2.02e-37 142.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_109_6 1234888.K0A2J2_9VIRU 3.97e-58 200.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_99567_2 1297569.MESS2_860020 1.78e-49 166.0 2CFWB@1|root,2Z8W6@2|Bacteria,1PRU1@1224|Proteobacteria,2TUGM@28211|Alphaproteobacteria,43MY9@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Antitoxin of toxin-antitoxin stability system - - - - - - - - - - - - - k59_99567_3 102129.Lepto7375DRAFT_7273 1.22e-16 77.4 2EHVE@1|root,33BKZ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_107870_1 1234888.K0A2R8_9VIRU 7.6e-23 100.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_66404_1 1234888.K0A2J2_9VIRU 1.28e-80 258.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_124445_1 1234888.K0A2J2_9VIRU 6.54e-129 388.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_124445_2 1234888.K0A2R8_9VIRU 3.34e-65 213.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_157609_1 426114.THI_1427 1.06e-07 59.3 COG1846@1|root,COG1846@2|Bacteria 2|Bacteria K DNA-binding transcription factor activity - - - - - - - - - - - - MarR,MarR_2 k59_50234_1 1986029.Q9MBM8_9VIRU 3.02e-36 141.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_25490_1 157072.XP_008878163.1 2.82e-07 60.1 COG5188@1|root,KOG2242@1|root,KOG2242@2759|Eukaryota,KOG2636@2759|Eukaryota 2759|Eukaryota A mRNA splicing, via spliceosome - - - ko:K12827 ko03040,map03040 M00352 - - ko00000,ko00001,ko00002,ko03041 - - - SF3A3,SPRY,Telomere_Sde2,Telomere_Sde2_2 k59_25490_2 1094755.MCO_01098 3.17e-14 82.8 COG4675@1|root,COG4675@2|Bacteria,1QWQH@1224|Proteobacteria,2UUR5@28211|Alphaproteobacteria,48TP9@772|Bartonellaceae 28211|Alphaproteobacteria S Phage Tail Collar Domain - - - - - - - - - - - - Collar k59_25490_3 1279038.KB907365_gene2 1.57e-11 80.1 COG3210@1|root,COG3210@2|Bacteria 2|Bacteria U domain, Protein - - 3.1.4.3 ko:K01114,ko:K12287 ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919 - R01312,R02027,R02052,R03332,R07381 RC00017,RC00425 ko00000,ko00001,ko01000,ko02042,ko02044 - - - Haemagg_act,SLH k59_240976_7 1234888.K0A2J2_9VIRU 6.78e-57 196.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_75206_1 428125.CLOLEP_01423 1.04e-41 153.0 2E2JP@1|root,32XP4@2|Bacteria,1VAIM@1239|Firmicutes,24PPR@186801|Clostridia,3WI4W@541000|Ruminococcaceae 186801|Clostridia S Phage tail protein - - - - - - - - - - - - Sipho_tail k59_141551_1 1538804.A0A088FAR2_9CAUD 1.37e-30 131.0 4QAQ9@10239|Viruses,4QPTV@28883|Caudovirales,4QKRS@10699|Siphoviridae 10699|Siphoviridae S Putative phage tail protein - GO:0005575,GO:0008150,GO:0016032,GO:0018995,GO:0019012,GO:0019058,GO:0019062,GO:0022610,GO:0030430,GO:0033643,GO:0033646,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044403,GO:0044406,GO:0044419,GO:0044650,GO:0051704 - - - - - - - - - - - k59_585_1 1234888.K0A2J2_9VIRU 9.12e-89 280.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_58547_11 411471.SUBVAR_04304 2.6e-28 129.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia,3WGRT@541000|Ruminococcaceae 186801|Clostridia L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_225010_6 999549.KI421514_gene16 4.14e-06 55.5 COG0863@1|root,COG0863@2|Bacteria,1R7RR@1224|Proteobacteria,2TS8Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - - - - - - - - - - - N6_N4_Mtase k59_225010_7 1120971.AUCA01000037_gene2882 5.59e-51 169.0 COG4725@1|root,COG4725@2|Bacteria,1TSJV@1239|Firmicutes 1239|Firmicutes KT Belongs to the MT-A70-like family - - - - - - - - - - - - MT-A70 k59_225010_8 1120998.AUFC01000019_gene320 4.13e-86 278.0 COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,3WCCT@538999|Clostridiales incertae sedis 186801|Clostridia L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_225010_9 469617.FUAG_02511 5.31e-09 64.7 COG3935@1|root,COG3935@2|Bacteria,37CI0@32066|Fusobacteria 32066|Fusobacteria L Psort location Cytoplasmic, score 8.96 - - - - - - - - - - - - - k59_200013_2 1618237.A0A0C5IMG6_9CIRC 1.62e-28 120.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_108849_2 1788449.A0A190WHL0_9CIRC 3e-69 219.0 4QBFZ@10239|Viruses,4QUKU@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_133873_1 1282360.ABAC460_10200 0.000434 50.1 COG4675@1|root,COG4675@2|Bacteria,1RESM@1224|Proteobacteria,2UQQX@28211|Alphaproteobacteria 28211|Alphaproteobacteria S tail collar domain protein - - - - - - - - - - - - - k59_258375_1 1196835.A458_06860 4.66e-35 139.0 COG3378@1|root,COG4643@1|root,COG3378@2|Bacteria,COG4643@2|Bacteria,1MVGY@1224|Proteobacteria,1S7S5@1236|Gammaproteobacteria,1Z0YY@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K06919 - - - - ko00000 - - - PriCT_2,Toprim_3,Toprim_4 k59_241499_1 1304275.C41B8_09081 4.73e-36 124.0 COG3668@1|root,COG3668@2|Bacteria,1N9UE@1224|Proteobacteria,1SCS6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S ParE toxin of type II toxin-antitoxin system, parDE - - - - - - - - - - - - ParE_toxin k59_241499_2 1458427.BAWN01000013_gene832 1.46e-10 58.9 29X8U@1|root,30IY7@2|Bacteria,1PYI3@1224|Proteobacteria,2WDQF@28216|Betaproteobacteria,4AIR8@80864|Comamonadaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_241499_3 381666.H16_A2471 4.64e-34 120.0 2F5MN@1|root,33Y6R@2|Bacteria,1NWTV@1224|Proteobacteria,2W2Y7@28216|Betaproteobacteria,1KDVV@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_241499_4 1366050.N234_14135 6.14e-38 127.0 2C7DZ@1|root,34AVX@2|Bacteria,1P2CB@1224|Proteobacteria,2W3YZ@28216|Betaproteobacteria,1KEC9@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_241499_5 471874.PROSTU_01039 4.96e-10 61.6 2EDFI@1|root,311UR@2|Bacteria,1Q48E@1224|Proteobacteria,1TEE3@1236|Gammaproteobacteria,3ZAE6@586|Providencia 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_241499_7 1488328.JMCL01000129_gene2738 1.61e-34 129.0 2EKAM@1|root,33E0W@2|Bacteria,1MYSP@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - RepL k59_142205_3 156889.Mmc1_1716 7.48e-73 230.0 28NGF@1|root,2ZBII@2|Bacteria,1R9KY@1224|Proteobacteria,2U1P7@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_34365_1 1120954.ATXE01000004_gene3 1.8e-08 60.5 COG1409@1|root,COG3420@1|root,COG1409@2|Bacteria,COG3420@2|Bacteria,2I9HA@201174|Actinobacteria 201174|Actinobacteria P Right handed beta helix region wcoB - - - - - - - - - - - Beta_helix,DUF1565 k59_17442_1 381666.H16_A2480 4.58e-172 499.0 COG3843@1|root,COG3843@2|Bacteria,1QZ0Y@1224|Proteobacteria,2VTP0@28216|Betaproteobacteria,1KBC9@119060|Burkholderiaceae 28216|Betaproteobacteria U MobA/MobL family - - - - - - - - - - - - MobA_MobL k59_34444_1 1220601.L7TLT7_9CAUD 2.43e-53 187.0 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales,4QI76@10662|Myoviridae 10662|Myoviridae S DNA helicase activity - - - - - - - - - - - - - k59_142306_1 926562.Oweho_2902 2.64e-14 69.3 COG0629@1|root,COG0629@2|Bacteria,4NT9M@976|Bacteroidetes,1I1XK@117743|Flavobacteriia,2PB63@246874|Cryomorphaceae 976|Bacteroidetes L Domain of unknown function (DUF3127) - - - - - - - - - - - - DUF3127 k59_117342_1 1408224.SAMCCGM7_c4358 2.54e-12 67.8 COG5565@1|root,COG5565@2|Bacteria,1R6R3@1224|Proteobacteria,2U1P9@28211|Alphaproteobacteria,4BDQ9@82115|Rhizobiaceae 28211|Alphaproteobacteria S DNA packaging protein gp2 - - - - - - - - - - - - Terminase_6,Terminase_6C k59_117342_2 398578.Daci_1943 1.02e-97 324.0 COG3064@1|root,COG3064@2|Bacteria,1R6JV@1224|Proteobacteria 1224|Proteobacteria M Membrane - - - - - - - - - - - - - k59_183547_2 1406780.U5PZU8_9CAUD 6.08e-36 141.0 4QBMV@10239|Viruses,4QUU6@35237|dsDNA viruses no RNA stage,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_208283_3 1204534.J9QD24_9CAUD 2.57e-14 68.9 4QBV5@10239|Viruses,4QVEI@35237|dsDNA viruses no RNA stage,4QPNX@28883|Caudovirales,4QKH1@10662|Myoviridae 10662|Myoviridae S Domain of Unknown Function with PDB structure (DUF3850) - - - - - - - - - - - - - k59_142308_2 95619.PM1_0217520 1.28e-05 46.2 COG2197@1|root,COG2197@2|Bacteria,1NA3X@1224|Proteobacteria 1224|Proteobacteria KT HNH endonuclease - - - - - - - - - - - - HNH_3 k59_200104_2 2003327.CAPSD_BPCHP 6.3e-15 77.4 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_59145_1 1134413.ANNK01000119_gene2442 9.45e-07 53.9 COG5283@1|root,COG5412@1|root,COG5283@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,4HU9A@91061|Bacilli 91061|Bacilli D Phage tail tape measure protein, TP901 family - - - - - - - - - - - - SLT k59_233212_2 349521.HCH_04562 2.93e-12 64.3 2BY2W@1|root,33316@2|Bacteria,1NA4T@1224|Proteobacteria,1SE5U@1236|Gammaproteobacteria,1XQIF@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k59_43392_4 105154.Q9MBU3_9VIRU 5.45e-07 56.6 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_43392_5 1385658.U5KPZ6_9VIRU 1.42e-136 413.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_192149_2 1089439.KB902241_gene994 1.33e-06 53.9 COG0494@1|root,COG0494@2|Bacteria,1RDGJ@1224|Proteobacteria,1S3PQ@1236|Gammaproteobacteria,460RN@72273|Thiotrichales 72273|Thiotrichales L Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage nudH - - ko:K08311 ko03018,map03018 - R10816 RC00002 ko00000,ko00001,ko01000,ko03019 - - - NUDIX k59_151221_3 1300143.CCAV010000006_gene4312 5.78e-14 71.6 COG4653@1|root,COG4653@2|Bacteria,4P9ZK@976|Bacteroidetes,1IM07@117743|Flavobacteriia,3ZTHB@59732|Chryseobacterium 976|Bacteroidetes S Phage capsid family - - - - - - - - - - - - - k59_250360_3 585502.HMPREF0645_2521 2.3e-08 56.6 2DP7B@1|root,330UW@2|Bacteria,4PN05@976|Bacteroidetes,2G0NB@200643|Bacteroidia 976|Bacteroidetes S Domain of unknown function (DUF4406) - - - - - - - - - - - - DUF4406 k59_250360_10 1266908.AQPB01000051_gene2445 4.25e-40 139.0 2AT0I@1|root,31IGD@2|Bacteria,1NAE0@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_175675_1 1385658.U5KPZ6_9VIRU 2.17e-66 219.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_59642_4 105154.Q9MBU6_9VIRU 8.02e-100 307.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_134619_1 1219035.NT2_13_00580 1.04e-29 122.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_34992_1 526227.Mesil_0575 3.08e-06 55.5 COG0210@1|root,COG0210@2|Bacteria 2|Bacteria L ATP-dependent DNA helicase activity - - - - - - - - - - - - AAA_19,UvrD-helicase,UvrD_C,UvrD_C_2 k59_109516_1 1692242.A0A0K1RL37_9CIRC 0.000897 46.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_242145_1 1379719.S5TMX6_9CIRC 7.58e-29 121.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_26938_5 428125.CLOLEP_03914 4.16e-09 63.9 COG1215@1|root,COG1216@1|root,COG2227@1|root,COG1215@2|Bacteria,COG1216@2|Bacteria,COG2227@2|Bacteria,1TQU0@1239|Firmicutes,248HP@186801|Clostridia,3WHZS@541000|Ruminococcaceae 186801|Clostridia M Glycosyltransferase, group 2 family protein - - - ko:K20444 - - - - ko00000,ko01000,ko01005,ko02000 4.D.1.3 GT2,GT4 - Glycos_transf_2 k59_250469_3 936596.HMPREF1495_0149 1.93e-22 94.7 COG0208@1|root,COG0208@2|Bacteria,1TQTH@1239|Firmicutes,249AN@186801|Clostridia 186801|Clostridia F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdB - 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_sm k59_119054_1 146922.JOFU01000008_gene3023 2.58e-07 55.1 COG2369@1|root,COG2369@2|Bacteria,2I59M@201174|Actinobacteria 201174|Actinobacteria S Phage Mu protein F like protein - - - - - - - - - - - - Phage_Mu_F k59_151962_1 935261.JAGL01000009_gene1177 1.8e-23 104.0 COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1QT52@1224|Proteobacteria,2TVNI@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Toprim-like - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - DnaB_C,Toprim_2 k59_201385_1 1788454.A0A190WHE4_9CIRC 6.46e-43 154.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_159674_1 49964.Q94MR7_9CAUD 4.57e-43 162.0 4QERB@10239|Viruses,4R014@35237|dsDNA viruses no RNA stage,4QTGJ@28883|Caudovirales,4QNZG@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_10390_1 1340810.V5UTB4_9CAUD 0.000121 50.4 4QB3T@10239|Viruses,4QWCJ@35237|dsDNA viruses no RNA stage,4QS7B@28883|Caudovirales,4QK0J@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_60175_1 1234888.K0A2J2_9VIRU 3.28e-79 252.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_159763_1 1136163.M565_ctg4P391 4.07e-05 52.4 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1XUAZ@135623|Vibrionales 135623|Vibrionales L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_102012_1 1692242.A0A0K1RL37_9CIRC 4.22e-57 189.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_102012_3 1692255.A0A0K1RL52_9CIRC 5.68e-26 105.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_68768_1 1234888.K0A2J2_9VIRU 6.31e-52 179.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_135381_1 932213.SPM24T3_09686 1.08e-34 130.0 COG0863@1|root,COG0863@2|Bacteria 2|Bacteria L N-4 methylation of cytosine - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_119172_1 1127518.H9C0Y5_9CAUD 4.75e-47 171.0 4QAW1@10239|Viruses,4QWUW@35237|dsDNA viruses no RNA stage,4QR8A@28883|Caudovirales,4QJW9@10662|Myoviridae 10662|Myoviridae S nucleic acid binding - - - - - - - - - - - - - k59_110406_3 291603.MREP_FBNY1 2.2e-14 77.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_184807_1 585503.HMPREF7545_1744 5.09e-05 55.5 2DBPZ@1|root,2ZABJ@2|Bacteria,1VJIG@1239|Firmicutes,4H5QI@909932|Negativicutes 909932|Negativicutes - - - - - - - - - - - - - - - k59_77880_2 913183.E5RV06_9CAUD 4.43e-32 117.0 4QASP@10239|Viruses,4QVR8@35237|dsDNA viruses no RNA stage,4QR4Z@28883|Caudovirales,4QNQ0@10744|Podoviridae 10744|Podoviridae S deoxyribonuclease IV (phage-T4-induced) activity - - - - - - - - - - - - - k59_251349_4 1385658.U5KNR1_9VIRU 3.39e-90 280.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_251349_6 105154.Q9MBU6_9VIRU 3.27e-227 644.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_260552_1 1454202.PPBDW_130632___1 4.33e-13 72.4 COG1974@1|root,COG1974@2|Bacteria,1RHIM@1224|Proteobacteria,1RSKU@1236|Gammaproteobacteria,1XZ6R@135623|Vibrionales 135623|Vibrionales K Peptidase S24-like - - - - - - - - - - - - HTH_3,Peptidase_S24 k59_44766_1 1385658.U5KNR1_9VIRU 3.22e-19 90.1 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_251460_1 1336243.JAEA01000002_gene2640 7.66e-20 82.4 COG4373@1|root,COG4373@2|Bacteria 2|Bacteria - - gp17a - - ko:K06909 - - - - ko00000 - - - Terminase_6,Terminase_6C k59_251460_2 1131814.JAFO01000001_gene2097 1.92e-11 67.8 COG3206@1|root,COG3206@2|Bacteria 2|Bacteria M extracellular polysaccharide biosynthetic process - - - ko:K06994 - - - - ko00000 - - - DUF4407,MMPL,Peptidase_S46,Wzz k59_11109_2 861208.AGROH133_06170 1.14e-32 127.0 COG3409@1|root,COG3772@1|root,COG3409@2|Bacteria,COG3772@2|Bacteria,1PSK5@1224|Proteobacteria,2U7GS@28211|Alphaproteobacteria,4BHG5@82115|Rhizobiaceae 28211|Alphaproteobacteria M Phage lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - PG_binding_1,Phage_lysozyme k59_128092_2 532075.B3VCW6_9CAUD 5.48e-18 82.8 4QAIK@10239|Viruses,4QUPH@35237|dsDNA viruses no RNA stage,4QPEB@28883|Caudovirales,4QNC3@10744|Podoviridae 10744|Podoviridae S endonuclease activity - - - - - - - - - - - - - k59_219713_2 216594.MMAR_4517 7.18e-09 58.5 COG0030@1|root,COG0030@2|Bacteria,2I4EV@201174|Actinobacteria,236GU@1762|Mycobacteriaceae 201174|Actinobacteria J Methyltransferase FkbM domain - - - - - - - - - - - - Methyltransf_21 k59_185578_1 1788444.A0A190WHB9_9CIRC 2.03e-20 89.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_160562_1 105154.Q9MBU6_9VIRU 2.33e-37 143.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_153460_28 95619.PM1_0217520 2.93e-15 76.6 COG2197@1|root,COG2197@2|Bacteria,1NA3X@1224|Proteobacteria 1224|Proteobacteria KT HNH endonuclease - - - - - - - - - - - - HNH_3 k59_153460_32 666685.R2APBS1_1628 9.17e-41 166.0 COG3598@1|root,COG3598@2|Bacteria 2|Bacteria L Psort location Cytoplasmic, score - - - - - - - - - - - - AAA_25,DUF927,HTH_23,Prim-Pol,RepB_primase k59_153460_34 317936.Nos7107_2419 9.24e-23 95.5 COG0338@1|root,COG0338@2|Bacteria,1G5RN@1117|Cyanobacteria,1HN98@1161|Nostocales 1117|Cyanobacteria L D12 class N6 adenine-specific DNA methyltransferase - - - - - - - - - - - - - k59_153460_35 1122243.KB903771_gene1522 2.44e-11 66.6 2C6KN@1|root,32Y69@2|Bacteria,1N8AV@1224|Proteobacteria,1SFCN@1236|Gammaproteobacteria 1236|Gammaproteobacteria S VRR-NUC domain - - - - - - - - - - - - VRR_NUC k59_153460_41 329254.Q2NPG0_9CAUD 6.48e-32 121.0 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales,4QKM7@10699|Siphoviridae 10699|Siphoviridae S HNH endonuclease - - - - - - - - - - - - - k59_252047_2 1692255.A0A0K1RL52_9CIRC 3.06e-85 265.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_103196_1 1385658.U5KPZ6_9VIRU 1.46e-148 437.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_29113_4 375286.mma_0323 1.94e-12 78.2 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2VJ57@28216|Betaproteobacteria,4724B@75682|Oxalobacteraceae 28216|Betaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_19806_1 105154.Q9MBU6_9VIRU 1.2e-73 240.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_78511_1 1609634.A0A0C5AFV4_9VIRU 7.63e-66 223.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_252049_1 1397284.AYMN01000028_gene3417 6.86e-33 133.0 COG0749@1|root,COG0749@2|Bacteria,1MWX7@1224|Proteobacteria,1S0Q1@1236|Gammaproteobacteria 1236|Gammaproteobacteria L ORF located using Glimmer RBSfinder - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A,DNA_pol_A_exo1 k59_145708_2 1121468.AUBR01000008_gene2081 9.85e-06 48.5 COG4570@1|root,COG4570@2|Bacteria,1UDK7@1239|Firmicutes,24T1T@186801|Clostridia,42INU@68295|Thermoanaerobacterales 186801|Clostridia L PFAM endodeoxyribonuclease RusA - - 3.1.22.4 ko:K01160 - - - - ko00000,ko01000,ko03400 - - - RusA k59_112190_1 1692249.A0A0K1RL40_9CIRC 1.9e-26 109.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_94760_1 532075.B3VCW4_9CAUD 1.87e-07 52.8 4QASG@10239|Viruses,4QZZU@35237|dsDNA viruses no RNA stage,4QT37@28883|Caudovirales,4QNXD@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_170293_1 1385658.U5KPZ6_9VIRU 3.88e-72 236.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_162215_1 1692242.A0A0K1RKZ2_9CIRC 1.14e-51 176.0 4QFEW@10239|Viruses,4QUKZ@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_162215_2 1692252.A0A0K1RL35_9CIRC 7.11e-86 267.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_5750_2 1096546.WYO_0183 3.18e-24 99.0 COG1670@1|root,COG1670@2|Bacteria,1PZYK@1224|Proteobacteria,2UN9Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - - - - - - - - - - - k59_244762_1 698486.D2XJA2_9CAUD 6.03e-16 85.1 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QKNE@10699|Siphoviridae 10699|Siphoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_244825_7 1234888.K0A2J2_9VIRU 3.69e-96 300.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_221923_1 1123388.AQWU01000057_gene2146 2.16e-14 84.3 COG0272@1|root,COG0272@2|Bacteria,1WJ4M@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 k59_204337_2 387093.SUN_1315 9.05e-09 60.8 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2YMQV@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_55123_1 351627.Csac_2765 1.84e-23 99.0 COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,2488C@186801|Clostridia,42F5R@68295|Thermoanaerobacterales 186801|Clostridia D PFAM Cobyrinic acid a,c-diamide synthase soj - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 k59_236398_3 1040987.AZUY01000006_gene1806 1.47e-25 117.0 COG3598@1|root,COG3598@2|Bacteria,1R4GJ@1224|Proteobacteria,2TUNT@28211|Alphaproteobacteria 28211|Alphaproteobacteria L AAA domain - - - - - - - - - - - - AAA_25 k59_105226_3 1618238.A0A0C5IB41_9CIRC 4.08e-20 96.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_87585_1 2003327.CAPSD_BPCHP 1.06e-22 104.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_31442_1 1449347.JQLN01000004_gene7007 4.98e-14 72.0 COG5323@1|root,COG5323@2|Bacteria,2I1XF@201174|Actinobacteria,2M5NQ@2063|Kitasatospora 201174|Actinobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6 k59_31442_2 290633.GOX2457 3.08e-29 115.0 COG5323@1|root,COG5323@2|Bacteria,1MW8S@1224|Proteobacteria,2TREI@28211|Alphaproteobacteria,2JWSP@204441|Rhodospirillales 204441|Rhodospirillales S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_55925_1 556268.OFAG_00945 1.8e-15 80.1 COG4675@1|root,COG4675@2|Bacteria,1R7VJ@1224|Proteobacteria,2W6EZ@28216|Betaproteobacteria,4781W@75682|Oxalobacteraceae 28216|Betaproteobacteria S tail collar domain protein - - - - - - - - - - - - Collar k59_139136_1 1148.1006576 1.92e-32 127.0 COG1876@1|root,COG1876@2|Bacteria,1G1RJ@1117|Cyanobacteria,1H5C7@1142|Synechocystis 1117|Cyanobacteria M D-alanyl-D-alanine carboxypeptidase - - 3.4.17.14 ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 M00651 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 - - - VanY k59_222961_2 1194526.A284_07970 5.75e-14 69.7 COG1525@1|root,COG1525@2|Bacteria,1W1ZK@1239|Firmicutes,4I0QU@91061|Bacilli,4GZMQ@90964|Staphylococcaceae 91061|Bacilli L COG1525 Micrococcal nuclease (thermonuclease) homologs - - 3.1.31.1 ko:K01174 - - - - ko00000,ko01000 - - - SNase k59_31443_1 1406785.U5PTZ8_9CAUD 2.03e-26 102.0 4QFIE@10239|Viruses,4QUGB@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_212384_1 1692250.A0A0K1RLR1_9CIRC 1.61e-15 84.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_263133_1 1537917.JU82_00020 1.32e-74 232.0 COG0553@1|root,COG0553@2|Bacteria,1PM15@1224|Proteobacteria,42ZGS@68525|delta/epsilon subdivisions,2YS8B@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria L DEAD-like helicases superfamily - - - - - - - - - - - - - k59_6945_1 172088.AUGA01000033_gene4627 5.44e-05 48.5 2FEUE@1|root,346TC@2|Bacteria,1MZPB@1224|Proteobacteria,2UC4Q@28211|Alphaproteobacteria,3K04T@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_195959_1 186617.M9M8L2_9VIRU 2.71e-37 142.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_48033_2 1056816.JAFQ01000004_gene4349 2.7e-14 72.8 2E1PK@1|root,32X02@2|Bacteria,2GUS8@201174|Actinobacteria,4G11C@85025|Nocardiaceae 201174|Actinobacteria S Protein of unknown function (DUF1353) - - - - - - - - - - - - DUF1353 k59_205374_1 375286.mma_2206 3.05e-08 55.5 COG5323@1|root,COG5323@2|Bacteria 2|Bacteria M Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6 k59_180134_2 202954.BBNK01000009_gene1213 8.07e-56 177.0 COG3108@1|root,COG3108@2|Bacteria,1RICX@1224|Proteobacteria,1S6D5@1236|Gammaproteobacteria,3NSUJ@468|Moraxellaceae 1236|Gammaproteobacteria S D-alanyl-D-alanine carboxypeptidase - - - ko:K17733 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M15_4 k59_223678_3 859653.HIMB5_00002850 6.83e-27 116.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,2TSF9@28211|Alphaproteobacteria,4BPP7@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_223678_5 1120980.JQKH01000093_gene1747 1.38e-88 284.0 COG2268@1|root,COG2268@2|Bacteria,1P39U@1224|Proteobacteria,2VMEW@28216|Betaproteobacteria,2KSU8@206351|Neisseriales 206351|Neisseriales S prohibitin homologues - - - - - - - - - - - - Band_7 k59_223678_6 309801.trd_0700 1.3e-17 87.8 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2G5J0@200795|Chloroflexi,27Y2S@189775|Thermomicrobia 189775|Thermomicrobia L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_139924_1 1298858.AUEL01000029_gene95 1.9e-52 194.0 COG1345@1|root,COG1345@2|Bacteria,1QZZ9@1224|Proteobacteria,2TZSX@28211|Alphaproteobacteria 28211|Alphaproteobacteria N Prophage tail length tape measure protein - - - - - - - - - - - - TMP_2 k59_189732_2 394.NGR_c11420 6.33e-05 45.4 COG1409@1|root,COG1409@2|Bacteria 2|Bacteria S acid phosphatase activity - - - - - - - - - - - - Big_5,Collagen,Peptidase_S74 k59_156415_2 1692250.A0A0K1RLR1_9CIRC 7.91e-89 274.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_80903_2 380358.XALC_1544 4.86e-57 191.0 COG2946@1|root,COG2946@2|Bacteria,1RDKM@1224|Proteobacteria,1S46D@1236|Gammaproteobacteria,1X9BS@135614|Xanthomonadales 135614|Xanthomonadales L Replication initiation factor - - - ko:K07467 - - - - ko00000 - - - Rep_trans k59_97061_1 1166948.JPZL01000002_gene1629 1.3e-18 84.0 2DRN8@1|root,33CCM@2|Bacteria,1NGRN@1224|Proteobacteria 1224|Proteobacteria - - - - 3.4.25.2 ko:K01419 - - - - ko00000,ko01000,ko01002 - - - - k59_97061_2 1380367.JIBC01000006_gene298 4.99e-37 134.0 2EKAP@1|root,33E0Y@2|Bacteria,1NAAI@1224|Proteobacteria,2UI39@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_14335_2 56110.Oscil6304_0470 4.62e-11 73.2 COG0739@1|root,COG3420@1|root,COG0739@2|Bacteria,COG3420@2|Bacteria,1G1GS@1117|Cyanobacteria,1H8FP@1150|Oscillatoriales 1117|Cyanobacteria M PFAM Peptidase family M23 - - 3.4.24.75 ko:K08259 - - - - ko00000,ko01000,ko01002,ko01011 - - - AMIN,LysM,Peptidase_M23 k59_123463_1 145579.CAPSD_BPPHM 4.5e-133 404.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_230637_1 1122201.AUAZ01000055_gene155 2.48e-41 156.0 2DI7K@1|root,3029C@2|Bacteria,1NIH6@1224|Proteobacteria,1STCP@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF1351) - - - - - - - - - - - - DUF1351 k59_32380_2 118005.AWNK01000003_gene2446 3.99e-26 106.0 COG3926@1|root,COG3926@2|Bacteria 2|Bacteria S Glycosyl hydrolase 108 - - - ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 - CHAP,Glyco_hydro_108,PG_binding_1 k59_7897_2 490913.B0FLN5_9CAUD 1.25e-183 526.0 4QGGR@10239|Viruses,4QZHR@35237|dsDNA viruses no RNA stage,4QUGZ@28883|Caudovirales,4QNY3@10744|Podoviridae 10744|Podoviridae S viral capsid - - - - - - - - - - - - - k59_7897_3 1477404.A0A023NGT6_9CAUD 4.12e-119 362.0 4QEQT@10239|Viruses,4QYJH@35237|dsDNA viruses no RNA stage,4QQ1B@28883|Caudovirales,4QNPW@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_7897_5 490913.C4NTE9_9CAUD 0.0 1064.0 4QF3C@10239|Viruses,4QWIA@35237|dsDNA viruses no RNA stage,4QU4U@28883|Caudovirales,4QNNQ@10744|Podoviridae 10744|Podoviridae S host cell wall - - - - - - - - - - - - - k59_7897_7 1477404.A0A023NGR5_9CAUD 1.95e-62 201.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QNX8@10744|Podoviridae 10744|Podoviridae S N-acetylmuramoyl-L-alanine amidase activity - GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0008150,GO:0008745,GO:0016032,GO:0016787,GO:0016810,GO:0016811,GO:0019048,GO:0019058,GO:0019076,GO:0031640,GO:0032897,GO:0035821,GO:0035890,GO:0035891,GO:0039633,GO:0040011,GO:0043900,GO:0043901,GO:0043903,GO:0044003,GO:0044004,GO:0044364,GO:0044403,GO:0044419,GO:0044659,GO:0044661,GO:0046782,GO:0048519,GO:0048525,GO:0050789,GO:0050792,GO:0051701,GO:0051704,GO:0051817,GO:0051818,GO:0051883,GO:0052126,GO:0052192,GO:0061783,GO:0065007 - - - - - - - - - - - k59_7897_9 1477404.A0A023NHY6_9CAUD 1.91e-54 173.0 4QGJ1@10239|Viruses,4QXHU@35237|dsDNA viruses no RNA stage,4QTXB@28883|Caudovirales,4QNRR@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_7897_10 490913.C4NTF5_9CAUD 2.25e-83 254.0 4QE35@10239|Viruses,4QYT7@35237|dsDNA viruses no RNA stage,4QQEJ@28883|Caudovirales,4QNWG@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_7897_11 490913.C4NTF6_9CAUD 0.0 901.0 4QEFX@10239|Viruses,4QYYG@35237|dsDNA viruses no RNA stage,4QRRV@28883|Caudovirales,4QNTK@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_7897_12 490913.C4NTF7_9CAUD 1.71e-128 369.0 4QGM6@10239|Viruses,4QYNV@35237|dsDNA viruses no RNA stage,4QRH4@28883|Caudovirales,4QP0P@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_7897_13 1477404.A0A023NHF3_9CAUD 4.38e-66 201.0 4QEB1@10239|Viruses,4QXE4@35237|dsDNA viruses no RNA stage,4QT2R@28883|Caudovirales,4QP3K@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_7897_14 1477404.A0A023NHY0_9CAUD 6.02e-110 345.0 4QCVP@10239|Viruses,4QZ92@35237|dsDNA viruses no RNA stage,4QR1Y@28883|Caudovirales,4QNCQ@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_206766_1 105154.Q9MBU6_9VIRU 3.62e-75 242.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_181653_1 573174.M4MBC3_9VIRU 9.98e-123 368.0 4QBY0@10239|Viruses,4QW35@35237|dsDNA viruses no RNA stage 10239|Viruses S AAA domain - - - - - - - - - - - - - k59_88660_4 1157490.EL26_22970 4.98e-21 97.8 COG2369@1|root,COG2369@2|Bacteria 2|Bacteria K cell adhesion - - - - - - - - - - - - Phage_Mu_F k59_238635_1 1609634.A0A0C5AFV4_9VIRU 7.23e-38 143.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_140848_1 865938.Weevi_0254 5.71e-39 144.0 COG1783@1|root,COG1783@2|Bacteria,4P9P0@976|Bacteroidetes,1I733@117743|Flavobacteriia 976|Bacteroidetes S Phage terminase large subunit - - - ko:K06909 - - - - ko00000 - - - Terminase_3 k59_74057_2 1089111.G8I7S6_9CAUD 6.34e-13 67.4 4QAV0@10239|Viruses,4QY41@35237|dsDNA viruses no RNA stage,4QSR9@28883|Caudovirales,4QKWJ@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_264840_1 1235661.K0IK58_9CAUD 2.93e-21 91.3 4QNC3@10744|Podoviridae 10744|Podoviridae S endonuclease activity - - - - - - - - - - - - - k59_23427_1 1408418.JNJH01000010_gene3507 3.02e-05 54.7 COG4723@1|root,COG4733@1|root,COG4723@2|Bacteria,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria,2UH0J@28211|Alphaproteobacteria 28211|Alphaproteobacteria MU Fibronectin type III domain protein - - - - - - - - - - - - Phage-tail_3 k59_15132_2 768679.TTX_1322a 5.69e-09 53.9 COG3369@1|root,arCOG01667@2157|Archaea,2XSEU@28889|Crenarchaeota 28889|Crenarchaeota S CDGSH-type zinc finger. Function unknown. - - - - - - - - - - - - zf-CDGSH k59_264841_1 279238.Saro_3004 1.08e-109 332.0 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1NKZK@1224|Proteobacteria,2U0EG@28211|Alphaproteobacteria,2KC8R@204457|Sphingomonadales 204457|Sphingomonadales S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6C k59_157096_1 759913.SDSE_1378 5.97e-56 194.0 COG4695@1|root,COG4695@2|Bacteria,1TP8B@1239|Firmicutes,4HBWE@91061|Bacilli 91061|Bacilli OU Phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_97758_4 1042163.BRLA_07p000010 9.83e-05 51.2 28KEB@1|root,3063N@2|Bacteria,1TZ4V@1239|Firmicutes,4I8BZ@91061|Bacilli,273D7@186822|Paenibacillaceae 91061|Bacilli - - - - - - - - - - - - - - - k59_181663_3 105154.Q9MBU6_9VIRU 5.93e-79 252.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_140867_1 145579.REP_BPPHM 2.86e-13 73.9 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_181666_2 1150991.H9NC40_9CAUD 6.23e-34 131.0 4QAIK@10239|Viruses,4QUPH@35237|dsDNA viruses no RNA stage,4QS4V@28883|Caudovirales,4QJ8C@10662|Myoviridae 10662|Myoviridae S DNA-dependent transcription, initiation - - - - - - - - - - - - - k59_132482_1 1417599.U6C6Y4_9CAUD 9.18e-41 147.0 4QF87@10239|Viruses,4QYZ4@35237|dsDNA viruses no RNA stage,4QPVW@28883|Caudovirales,4QNV3@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_264846_2 469378.Ccur_14140 7.33e-14 80.1 COG1475@1|root,COG1475@2|Bacteria,2GNRN@201174|Actinobacteria,4CUFM@84998|Coriobacteriia 84998|Coriobacteriia K Belongs to the ParB family - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_140869_1 686578.AFFX01000004_gene3910 3.47e-05 45.8 2E5K5@1|root,330BC@2|Bacteria,1RG8X@1224|Proteobacteria,1S3Z1@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Siphovirus Gp157 - - - - - - - - - - - - Sipho_Gp157 k59_98549_1 194802.Q8LT46_9CAUD 2.46e-09 63.9 4QE6E@10239|Viruses,4QV23@35237|dsDNA viruses no RNA stage,4QTFG@28883|Caudovirales 28883|Caudovirales S protein dimerization activity - - - - - - - - - - - - - k59_256440_2 1540097.A0A0A0YW88_9CAUD 2.11e-53 187.0 4QGA5@10239|Viruses,4QT9N@28883|Caudovirales,4QP47@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_16054_2 1288298.rosmuc_03156 4.66e-11 67.8 COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,2TRU2@28211|Alphaproteobacteria,46P8R@74030|Roseovarius 28211|Alphaproteobacteria L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 k59_165611_2 1618248.A0A0C5IB82_9CIRC 1.27e-103 311.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_165611_3 1692242.A0A0K1RKZ2_9CIRC 1.21e-45 159.0 4QFEW@10239|Viruses,4QUKZ@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_232170_1 1556290.A0A0A0RQI3_9CAUD 2.31e-37 149.0 4QCZC@10239|Viruses,4QRH3@28883|Caudovirales,4QM07@10699|Siphoviridae 10699|Siphoviridae S Bacterial DNA polymerase III alpha subunit - - - - - - - - - - - - - k59_232170_2 536232.CLM_2557 2.41e-05 48.1 COG1694@1|root,COG1694@2|Bacteria 2|Bacteria FG Mazg nucleotide pyrophosphohydrolase - - - - - - - - - - - - MazG k59_232170_3 314254.OA2633_04776 2.24e-32 131.0 COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,2TRPR@28211|Alphaproteobacteria,43W8I@69657|Hyphomonadaceae 28211|Alphaproteobacteria L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071496 - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA k59_82703_1 1380367.JIBC01000006_gene303 4.67e-37 144.0 28JKJ@1|root,2Z9DD@2|Bacteria,1MUN2@1224|Proteobacteria,2TST4@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Phage P22-like portal protein - - - - - - - - - - - - P22_portal k59_214783_2 118173.KB235914_gene2591 2.46e-08 58.5 COG4627@1|root,COG4627@2|Bacteria,1G57B@1117|Cyanobacteria,1HAWR@1150|Oscillatoriales 1117|Cyanobacteria S Methyltransferase domain - - - - - - - - - - - - Methyltransf_11 k59_214783_4 349520.PPE_03839 2.79e-15 81.6 COG1216@1|root,COG1216@2|Bacteria,1V5RV@1239|Firmicutes,4HIMX@91061|Bacilli,26TUK@186822|Paenibacillaceae 91061|Bacilli S glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 k59_264986_1 1788438.A0A190WHE1_9CIRC 2.73e-32 128.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_265019_2 1692249.A0A0K1RLN8_9CIRC 6.36e-19 86.3 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_198693_2 1618258.A0A0C5I9K3_9CIRC 5.15e-19 95.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_165846_2 1692242.A0A0K1RKZ2_9CIRC 1.97e-35 135.0 4QFEW@10239|Viruses,4QUKZ@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_65624_1 349521.HCH_02886 1.39e-46 158.0 COG3023@1|root,COG3023@2|Bacteria,1N032@1224|Proteobacteria,1SFIP@1236|Gammaproteobacteria,1XPM6@135619|Oceanospirillales 135619|Oceanospirillales V N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - Amidase_2 k59_239930_1 1385658.U5KPZ6_9VIRU 2.02e-71 232.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_239930_3 1165094.RINTHH_3920 1.02e-07 55.5 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_41196_1 1234888.K0A2J2_9VIRU 1.41e-31 121.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_165852_2 768706.Desor_0336 1.38e-11 68.9 COG0451@1|root,COG0451@2|Bacteria,1VP6I@1239|Firmicutes,251A8@186801|Clostridia,262EW@186807|Peptococcaceae 186801|Clostridia M PFAM NAD dependent epimerase dehydratase family - - 4.2.1.45,4.2.1.46,5.1.3.2 ko:K01709,ko:K01710,ko:K01784 ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130 M00361,M00362,M00632,M00793 R00291,R02426,R02984,R06513 RC00289,RC00402 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd k59_24828_1 429009.Adeg_1177 1e-48 168.0 COG3598@1|root,COG3598@2|Bacteria,1UKDF@1239|Firmicutes,25FUJ@186801|Clostridia,42GPU@68295|Thermoanaerobacterales 186801|Clostridia L PFAM Bifunctional DNA primase polymerase - - - - - - - - - - - - PriCT_1,Prim-Pol k59_24828_2 1149133.ppKF707_0761 1.08e-12 63.2 2BGXD@1|root,32AXC@2|Bacteria,1QFDG@1224|Proteobacteria,1TCKV@1236|Gammaproteobacteria,1YKF6@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Prokaryotic dksA/traR C4-type zinc finger - - - - - - - - - - - - zf-dskA_traR k59_249252_1 1121403.AUCV01000017_gene4519 1.47e-10 68.2 COG5276@1|root,COG5276@2|Bacteria,1R0W0@1224|Proteobacteria,43D23@68525|delta/epsilon subdivisions 1224|Proteobacteria S Protein of unknown function (DUF1566) - - - - - - - - - - - - DUF1566 k59_224373_1 192875.XP_004364588.1 1.92e-36 141.0 COG0187@1|root,KOG0355@2759|Eukaryota,38CPA@33154|Opisthokonta 33154|Opisthokonta B DNA topoisomerase type II (ATP-hydrolyzing) activity TOP2 GO:0000003,GO:0000018,GO:0000019,GO:0000070,GO:0000075,GO:0000166,GO:0000228,GO:0000278,GO:0000280,GO:0000712,GO:0000775,GO:0000785,GO:0000790,GO:0000793,GO:0000794,GO:0000795,GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005739,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006265,GO:0006271,GO:0006275,GO:0006310,GO:0006323,GO:0006325,GO:0006333,GO:0006338,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007076,GO:0007093,GO:0007127,GO:0007131,GO:0007346,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022402,GO:0022414,GO:0022616,GO:0030261,GO:0030554,GO:0031055,GO:0031323,GO:0031326,GO:0031570,GO:0031974,GO:0031981,GO:0032553,GO:0032555,GO:0032559,GO:0034506,GO:0034641,GO:0034645,GO:0035327,GO:0035639,GO:0035825,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044454,GO:0044464,GO:0044774,GO:0045132,GO:0045786,GO:0045930,GO:0046483,GO:0048285,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0051276,GO:0051304,GO:0051306,GO:0051307,GO:0051321,GO:0051726,GO:0060255,GO:0061505,GO:0061982,GO:0065007,GO:0070013,GO:0071103,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090329,GO:0097046,GO:0097047,GO:0097159,GO:0097367,GO:0098687,GO:0098813,GO:0099086,GO:0140013,GO:0140014,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:1903046,GO:1903047,GO:2000112,GO:2000621 5.99.1.3 ko:K03164 ko01524,map01524 - - - ko00000,ko00001,ko01000,ko03032,ko03036 - - - DNA_gyraseB,DNA_topoisoIV,HATPase_c,TOPRIM_C,Toprim k59_224373_2 7091.BGIBMGA011615-TA 1.38e-28 117.0 COG0187@1|root,KOG0355@2759|Eukaryota,38CPA@33154|Opisthokonta,3BFVW@33208|Metazoa,3CW22@33213|Bilateria,41X4Y@6656|Arthropoda,3SGDZ@50557|Insecta,443YE@7088|Lepidoptera 33208|Metazoa B Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks TOP2B GO:0000003,GO:0000070,GO:0000075,GO:0000166,GO:0000182,GO:0000217,GO:0000228,GO:0000278,GO:0000280,GO:0000287,GO:0000302,GO:0000400,GO:0000712,GO:0000785,GO:0000790,GO:0000792,GO:0000793,GO:0000819,GO:0000902,GO:0000904,GO:0001764,GO:0002244,GO:0002376,GO:0002520,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003690,GO:0003696,GO:0003723,GO:0003729,GO:0003824,GO:0003916,GO:0003918,GO:0005080,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005730,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006265,GO:0006266,GO:0006282,GO:0006310,GO:0006323,GO:0006325,GO:0006342,GO:0006355,GO:0006357,GO:0006725,GO:0006807,GO:0006915,GO:0006921,GO:0006928,GO:0006950,GO:0006974,GO:0006979,GO:0006996,GO:0007049,GO:0007059,GO:0007060,GO:0007076,GO:0007093,GO:0007127,GO:0007131,GO:0007140,GO:0007143,GO:0007154,GO:0007275,GO:0007276,GO:0007292,GO:0007346,GO:0007399,GO:0007409,GO:0007417,GO:0007420,GO:0007568,GO:0007569,GO:0007584,GO:0008022,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008219,GO:0008283,GO:0008301,GO:0008623,GO:0009058,GO:0009059,GO:0009314,GO:0009330,GO:0009605,GO:0009628,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010035,GO:0010212,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010639,GO:0010941,GO:0010942,GO:0012501,GO:0014070,GO:0014074,GO:0016043,GO:0016321,GO:0016458,GO:0016462,GO:0016477,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0019899,GO:0019900,GO:0019901,GO:0019953,GO:0021533,GO:0021549,GO:0021575,GO:0021587,GO:0021680,GO:0021681,GO:0021683,GO:0021684,GO:0021692,GO:0021694,GO:0021695,GO:0021696,GO:0021697,GO:0021702,GO:0021707,GO:0021953,GO:0022008,GO:0022037,GO:0022402,GO:0022411,GO:0022412,GO:0022414,GO:0030030,GO:0030097,GO:0030154,GO:0030182,GO:0030261,GO:0030262,GO:0030263,GO:0030332,GO:0030554,GO:0030900,GO:0030902,GO:0031010,GO:0031175,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031570,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0031974,GO:0031981,GO:0032182,GO:0032501,GO:0032502,GO:0032504,GO:0032553,GO:0032555,GO:0032559,GO:0032989,GO:0032990,GO:0032991,GO:0033043,GO:0033044,GO:0033198,GO:0033554,GO:0034599,GO:0034614,GO:0034641,GO:0034645,GO:0035639,GO:0035690,GO:0035825,GO:0036094,GO:0040011,GO:0040016,GO:0040029,GO:0042221,GO:0042493,GO:0042542,GO:0042623,GO:0042752,GO:0042802,GO:0042803,GO:0042826,GO:0042981,GO:0043021,GO:0043065,GO:0043067,GO:0043068,GO:0043130,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043565,GO:0043900,GO:0043902,GO:0043903,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044454,GO:0044464,GO:0044703,GO:0044774,GO:0044877,GO:0045069,GO:0045070,GO:0045091,GO:0045132,GO:0045739,GO:0045786,GO:0045814,GO:0045870,GO:0045892,GO:0045893,GO:0045930,GO:0045934,GO:0045935,GO:0045944,GO:0046483,GO:0046677,GO:0046683,GO:0046872,GO:0046982,GO:0046983,GO:0048232,GO:0048285,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048524,GO:0048534,GO:0048583,GO:0048584,GO:0048609,GO:0048646,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048870,GO:0050000,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051173,GO:0051179,GO:0051234,GO:0051252,GO:0051253,GO:0051254,GO:0051276,GO:0051301,GO:0051303,GO:0051304,GO:0051306,GO:0051307,GO:0051309,GO:0051310,GO:0051321,GO:0051640,GO:0051641,GO:0051649,GO:0051656,GO:0051674,GO:0051704,GO:0051716,GO:0051726,GO:0060255,GO:0060322,GO:0061505,GO:0061564,GO:0061982,GO:0065007,GO:0070013,GO:0070301,GO:0070603,GO:0070887,GO:0071103,GO:0071107,GO:0071236,GO:0071310,GO:0071318,GO:0071407,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0071840,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0097159,GO:0097194,GO:0097237,GO:0097367,GO:0098813,GO:0120036,GO:0120039,GO:0140013,GO:0140014,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902494,GO:1902679,GO:1902680,GO:1903046,GO:1903047,GO:1903506,GO:1903507,GO:1903508,GO:1903900,GO:1903902,GO:1904949,GO:1905462,GO:1905463,GO:1990837,GO:1990904,GO:2000112,GO:2000113,GO:2000779,GO:2000781,GO:2001020,GO:2001022,GO:2001032,GO:2001034,GO:2001141,GO:2001251 5.99.1.3 ko:K03164 ko01524,map01524 - - - ko00000,ko00001,ko01000,ko03032,ko03036 - - - DNA_gyraseB,DNA_topoisoIV,DTHCT,HATPase_c,TOPRIM_C,Toprim k59_33680_1 420324.KI911970_gene1456 2.32e-32 134.0 28IA2@1|root,2Z8CQ@2|Bacteria,1PQM2@1224|Proteobacteria,2TUAP@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_25446_2 717785.HYPMC_1249 1.65e-16 83.2 2DSQT@1|root,33H37@2|Bacteria 2|Bacteria S Protein of unknown function (DUF2793) - - - - - - - - - - - - DUF2793 k59_507_2 1692244.A0A0K1RLR5_9CIRC 8.56e-109 322.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_75158_1 428125.CLOLEP_01411 6.87e-16 79.0 28J3N@1|root,2Z8ZU@2|Bacteria,1V15Z@1239|Firmicutes,249Z0@186801|Clostridia,3WNJZ@541000|Ruminococcaceae 186801|Clostridia S Phage portal protein - - - - - - - - - - - - Phage_portal k59_75158_2 691965.D4P7D6_9CAUD 5.46e-33 132.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_42038_10 1556290.A0A0A0RL61_9CAUD 7.89e-67 223.0 4QAK6@10239|Viruses,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - GO:0005575,GO:0019012,GO:0019028,GO:0032991,GO:0044423,GO:0046806 - - - - - - - - - - - k59_42038_12 1556290.A0A0A0RM05_9CAUD 2.34e-136 411.0 4QAYV@10239|Viruses,4QPU3@28883|Caudovirales,4QKKX@10699|Siphoviridae 10699|Siphoviridae S Phage portal protein - - - - - - - - - - - - - k59_42038_16 1172188.KB911820_gene2885 4.2e-286 805.0 COG0209@1|root,COG0209@2|Bacteria,2IC1H@201174|Actinobacteria 201174|Actinobacteria F Ribonucleotide reductase, barrel domain - - - - - - - - - - - - Ribonuc_red_lgC k59_133374_3 1219035.NT2_13_00580 4.6e-18 86.7 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_108338_1 1692258.A0A0K1RL51_9CIRC 1.93e-38 139.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_207777_3 1094508.Tsac_2416 6.44e-55 208.0 COG1345@1|root,COG5280@1|root,COG5412@1|root,COG1345@2|Bacteria,COG5280@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,247QT@186801|Clostridia,42GRZ@68295|Thermoanaerobacterales 186801|Clostridia N tail tape measure protein TP901 core region - - - - - - - - - - - - PhageMin_Tail k59_174493_2 331869.BAL199_17183 1.46e-78 247.0 COG5323@1|root,COG5323@2|Bacteria,1MW8S@1224|Proteobacteria,2TREI@28211|Alphaproteobacteria,4BR8D@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_3,Terminase_6,Terminase_6C k59_17041_1 1609634.A0A0C5AFV4_9VIRU 3.99e-119 360.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_17041_3 1609634.A0A0C5AFT2_9VIRU 1.03e-109 328.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_116694_3 1556290.A0A0A0RQH0_9CAUD 4.74e-20 98.6 4QAK6@10239|Viruses,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_8906_1 82654.Pse7367_3857 2.6e-15 84.7 COG4388@1|root,COG4388@2|Bacteria,1GF8C@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - k59_8906_2 296591.Bpro_3746 0.000176 46.2 2EPH2@1|root,33H3P@2|Bacteria,1NBTX@1224|Proteobacteria,2VY22@28216|Betaproteobacteria 28216|Betaproteobacteria S protein B3ORF37 Bacteriophage B3 gi 33338631 gb AAQ13955.1 - - - - - - - - - - - - - k59_133377_1 1609634.A0A0C5AFV4_9VIRU 1.2e-65 219.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_225359_1 1400524.KL370779_gene619 2.59e-13 73.9 COG0300@1|root,COG0300@2|Bacteria,1NYHT@1224|Proteobacteria,2UTXW@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short k59_1611_3 749413.E5DV94_9VIRU 5.48e-09 55.1 4QAZF@10239|Viruses,4QUTY@35237|dsDNA viruses no RNA stage 10239|Viruses S Protein of unknwon function (DUF3310) - - - - - - - - - - - - - k59_1611_4 1160721.RBI_I01166 4.39e-07 55.5 COG1896@1|root,COG1896@2|Bacteria,1TSDU@1239|Firmicutes,24FT8@186801|Clostridia,3WGMJ@541000|Ruminococcaceae 186801|Clostridia S PFAM metal-dependent phosphohydrolase HD sub domain yfbR - 3.1.3.89 ko:K07023,ko:K08722 ko00240,ko01100,map00240,map01100 - R01569,R01664,R01968,R02088,R02102,R10776 RC00017 ko00000,ko00001,ko01000 - - - HD_2,HD_3 k59_1611_5 1980924.B2ZYD3_9CAUD 7.89e-68 224.0 4QBA2@10239|Viruses,4QPPI@28883|Caudovirales,4QIA3@10662|Myoviridae 10662|Myoviridae S Thymidylate synthase - - - - - - - - - - - - - k59_1611_6 5341.XP_007333176.1 8.9e-08 60.8 28HY4@1|root,2S2AC@2759|Eukaryota,3A4KP@33154|Opisthokonta,3P4W1@4751|Fungi,3V1CI@5204|Basidiomycota,22917@155619|Agaricomycetes,3W52T@5338|Agaricales 4751|Fungi B Chromo (CHRromatin Organisation MOdifier) domain - - - - - - - - - - - - Chromo k59_158681_2 1618254.A0A0C5IBG4_9CIRC 1.72e-111 328.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_26487_4 1105367.CG50_10630 5.54e-13 80.9 COG2911@1|root,COG5281@1|root,COG5283@1|root,COG2911@2|Bacteria,COG5281@2|Bacteria,COG5283@2|Bacteria,1QU6S@1224|Proteobacteria,2TXGV@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Lambda phage tail tape-measure protein (Tape_meas_lam_C) - - - - - - - - - - - - Tape_meas_lam_C k59_26487_9 172088.AUGA01000106_gene3334 9.12e-07 55.5 2D2PS@1|root,32TD8@2|Bacteria,1N5HS@1224|Proteobacteria,2UDMM@28211|Alphaproteobacteria,3JZ1B@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_142546_1 1609634.A0A0C5AFV4_9VIRU 2.62e-99 307.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_142546_3 1165094.RINTHH_3920 2.16e-48 169.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_26488_2 65393.PCC7424_4450 5.24e-13 71.2 COG0863@1|root,COG2189@1|root,COG0863@2|Bacteria,COG2189@2|Bacteria,1G2XK@1117|Cyanobacteria,3KIMP@43988|Cyanothece 1117|Cyanobacteria H PFAM DNA methylase N-4 N-6 domain protein - - 2.1.1.72 ko:K00571,ko:K07319 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_175254_2 428125.CLOLEP_01423 3.88e-49 172.0 2E2JP@1|root,32XP4@2|Bacteria,1VAIM@1239|Firmicutes,24PPR@186801|Clostridia,3WI4W@541000|Ruminococcaceae 186801|Clostridia S Phage tail protein - - - - - - - - - - - - Sipho_tail k59_175254_4 428125.CLOLEP_01425 9.29e-31 127.0 292XD@1|root,2ZQEV@2|Bacteria,1V48I@1239|Firmicutes,24GZD@186801|Clostridia,3WNVV@541000|Ruminococcaceae 186801|Clostridia S COG NOG18825 non supervised orthologous group - - - - - - - - - - - - - k59_84147_2 714943.Mucpa_3747 2.7e-07 60.5 COG4733@1|root,COG4733@2|Bacteria,4NTXR@976|Bacteroidetes,1IZ2D@117747|Sphingobacteriia 976|Bacteroidetes S Concanavalin A-like lectin/glucanases superfamily - - - - - - - - - - - - CHU_C,Laminin_G_3 k59_183676_1 1618238.A0A0C5I2G8_9CIRC 3.81e-37 140.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_183676_3 46681.XP_001738227.1 6.41e-36 138.0 2CSEE@1|root,2RBK2@2759|Eukaryota,3X9MH@554915|Amoebozoa 554915|Amoebozoa G RNA helicase - - - - - - - - - - - - RNA_helicase k59_125943_1 948870.I7HJC6_9CAUD 1.12e-118 370.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QI6A@10662|Myoviridae 10662|Myoviridae S Ribonucleotide reductase, barrel domain - - - - - - - - - - - - - k59_200294_1 1234888.K0A2R8_9VIRU 1.1e-39 143.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_158739_1 1128073.G9LQV6_9CIRC 1.49e-34 135.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_84232_1 1477404.A0A023NH90_9CAUD 1.03e-17 82.4 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_84232_2 490913.C4NTD0_9CAUD 4e-191 543.0 4QBY0@10239|Viruses,4QW35@35237|dsDNA viruses no RNA stage,4QQ4Q@28883|Caudovirales,4QNNN@10744|Podoviridae 10744|Podoviridae S UvrD-like helicase C-terminal domain - - - - - - - - - - - - - k59_225490_2 1121934.AUDX01000028_gene491 2.8e-20 92.0 COG2071@1|root,COG2071@2|Bacteria,2HRHB@201174|Actinobacteria,4FTGV@85023|Microbacteriaceae 201174|Actinobacteria S Peptidase C26 - - - ko:K07010 - - - - ko00000,ko01002 - - - Peptidase_C26 k59_200370_1 1120979.ATVB01000007_gene1117 1.44e-06 55.1 28MKK@1|root,2ZAWR@2|Bacteria,2IS2W@201174|Actinobacteria,4D1DD@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - RNA_helicase,Viral_Rep k59_35382_1 1122962.AULH01000009_gene3850 3.64e-23 117.0 2DKW9@1|root,30JFD@2|Bacteria,1QZ8U@1224|Proteobacteria,2U83R@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_184550_1 1120936.KB907208_gene1116 3.58e-33 127.0 2FA48@1|root,342D2@2|Bacteria,2H6VX@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_2659_1 1005395.CSV86_06226 3.75e-21 95.1 COG3206@1|root,COG3206@2|Bacteria,1ND5H@1224|Proteobacteria,1RNXC@1236|Gammaproteobacteria 1236|Gammaproteobacteria M DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease - - - - - - - - - - - - Rad52_Rad22 k59_93310_3 145579.H_BPPHM 1.14e-22 97.4 4QCA6@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_93310_4 145579.CAPSD_BPPHM 1.31e-224 637.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_93310_5 145579.REP_BPPHM 9e-97 295.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_192535_1 932213.SPM24T3_23642 2.75e-29 109.0 COG5614@1|root,COG5614@2|Bacteria,1N9Y5@1224|Proteobacteria,1SE8T@1236|Gammaproteobacteria,405JB@613|Serratia 1236|Gammaproteobacteria S COG5614 Bacteriophage head-tail adaptor - - - - - - - - - - - - Phage_H_T_join k59_192535_4 760568.Desku_2077 0.000458 47.8 COG0500@1|root,COG2226@2|Bacteria,1UY28@1239|Firmicutes,24GXH@186801|Clostridia,262Q6@186807|Peptococcaceae 186801|Clostridia Q Nodulation protein S (NodS) - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 k59_192535_7 1123279.ATUS01000005_gene3105 8.75e-41 142.0 2DNB5@1|root,32WIW@2|Bacteria,1N0BM@1224|Proteobacteria,1S8UT@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Bacteriophage HK97-gp10, putative tail-component - - - - - - - - - - - - HK97-gp10_like k59_192535_8 443152.MDG893_20584 2.38e-43 145.0 2DM6W@1|root,32UGB@2|Bacteria,1N425@1224|Proteobacteria,1SB1W@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF3168) - - - - - - - - - - - - DUF3168 k59_192535_9 932213.SPM24T3_24191 3.64e-57 183.0 2DNA4@1|root,32WDI@2|Bacteria,1RFBA@1224|Proteobacteria,1T5E0@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage tail tube, TTP, lambda-like - - - - - - - - - - - - Phage_TTP_11 k59_192535_10 443152.MDG893_20574 1.04e-41 140.0 2CHRA@1|root,32S6D@2|Bacteria,1MZ8I@1224|Proteobacteria,1SHSQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage tail assembly chaperone, TAC - - - - - - - - - - - - Phage_TAC_13 k59_192535_11 335283.Neut_1460 1.62e-64 238.0 COG1196@1|root,COG1345@1|root,COG1196@2|Bacteria,COG1345@2|Bacteria,1PDRQ@1224|Proteobacteria,2W14R@28216|Betaproteobacteria 28216|Betaproteobacteria D Prophage tail length tape measure protein - - - - - - - - - - - - TMP_2 k59_192535_14 1397284.AYMN01000070_gene2146 3.51e-22 100.0 COG5449@1|root,COG5449@2|Bacteria,1MXK2@1224|Proteobacteria,1S5T3@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage conserved hypothetical protein BR0599 - - - - - - - - - - - - DUF2163,Phage_BR0599 k59_192535_15 335283.Neut_1457 1.09e-25 97.1 2CJX7@1|root,32W32@2|Bacteria,1N82M@1224|Proteobacteria,2VY34@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_192535_16 335283.Neut_1456 9.32e-17 74.3 2EK40@1|root,33DUE@2|Bacteria,1NJE0@1224|Proteobacteria,2W5HA@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_192535_17 335283.Neut_1455 2.76e-175 552.0 COG2304@1|root,COG4733@1|root,COG2304@2|Bacteria,COG4733@2|Bacteria,1MXB4@1224|Proteobacteria,2VJS7@28216|Betaproteobacteria 28216|Betaproteobacteria M Putative phage tail protein - - - - - - - - - - - - Phage-tail_3 k59_84720_1 759938.F5BSB4_9CIRC 3.01e-13 74.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_201239_3 1205681.CALW02000103_gene1536 3.89e-29 108.0 2EE3H@1|root,337Y3@2|Bacteria,1NF3P@1224|Proteobacteria,2UKX4@28211|Alphaproteobacteria,48U9U@772|Bartonellaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_110299_3 645127.ckrop_1618 1.43e-10 61.6 2B5DG@1|root,31Y7V@2|Bacteria,2HZRF@201174|Actinobacteria,22PT9@1653|Corynebacteriaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_160619_3 1278971.AOGF01000034_gene1751 4.7e-15 75.5 2D0K9@1|root,32T8S@2|Bacteria,1MZRW@1224|Proteobacteria,1SF0N@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_202513_1 794903.OPIT5_03855 2.54e-46 172.0 COG5511@1|root,COG5511@2|Bacteria 2|Bacteria F Phage portal protein, lambda family - - - - - - - - - - - - Phage_portal_2 k59_202513_2 1144307.PMI04_03650 3.54e-53 187.0 COG4653@1|root,COG4653@2|Bacteria,1MWMB@1224|Proteobacteria,2TUJN@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Phage capsid family - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_69763_3 266809.PM03_15090 6.54e-95 290.0 COG3409@1|root,COG4322@1|root,COG3409@2|Bacteria,COG4322@2|Bacteria,1NCJ6@1224|Proteobacteria,2U1UB@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Putative peptidoglycan binding domain - - - - - - - - - - - - PG_binding_1 k59_136299_1 691965.D4P7I3_9CAUD 4.3e-111 358.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_119911_2 269796.Rru_A1278 8.22e-33 126.0 28N1N@1|root,2ZB7Q@2|Bacteria,1R86T@1224|Proteobacteria,2U0A6@28211|Alphaproteobacteria,2JRMI@204441|Rhodospirillales 204441|Rhodospirillales H Sulfotransferase domain - - - - - - - - - - - - Sulfotransfer_1 k59_243601_2 1121438.JNJA01000039_gene1897 3.12e-05 51.6 2DNH7@1|root,32XH1@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_85595_4 439292.Bsel_3020 4.26e-44 161.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4H9YP@91061|Bacilli 91061|Bacilli L SNF2 family - - - - - - - - - - - - Helicase_C,SNF2_N k59_36333_3 1410620.SHLA_4c000960 9.06e-17 75.1 294X4@1|root,2ZSA4@2|Bacteria,1P7D5@1224|Proteobacteria,2UX4Z@28211|Alphaproteobacteria,4BKDN@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_60981_3 402626.Rpic_2548 1.9e-62 210.0 COG0464@1|root,COG0464@2|Bacteria,1QU82@1224|Proteobacteria,2WHSD@28216|Betaproteobacteria,1KFRP@119060|Burkholderiaceae 28216|Betaproteobacteria O PFAM Zonular occludens toxin - - - ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko02042 - - - Zot k59_202515_1 1094496.m07a_12040 3.24e-14 78.2 COG3170@1|root,COG3170@2|Bacteria,1R69E@1224|Proteobacteria,2U3B9@28211|Alphaproteobacteria,48TPA@772|Bartonellaceae 28211|Alphaproteobacteria NU Phage P22-like portal protein - - - - - - - - - - - - P22_portal k59_111574_1 1234888.K0A2J2_9VIRU 9.83e-160 467.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_102856_4 247490.KSU1_D0852 0.000275 46.6 COG1396@1|root,COG1396@2|Bacteria 2|Bacteria K sequence-specific DNA binding - - - - - - - - - - - - HTH_19,HTH_3,HTH_31 k59_102856_7 1219035.NT2_01_04700 1.63e-22 93.2 2DPAY@1|root,331AT@2|Bacteria,1N6ZM@1224|Proteobacteria,2UG3N@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - ASCH k59_102856_9 470.IX87_18615 5.14e-40 148.0 COG3756@1|root,COG3756@2|Bacteria,1N7G4@1224|Proteobacteria,1SEVU@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - DUF1376 k59_169718_3 1692249.A0A0K1RL40_9CIRC 5.1e-63 203.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_260808_1 696369.KI912183_gene1990 5.42e-17 84.3 COG1573@1|root,COG1573@2|Bacteria,1V267@1239|Firmicutes,24DFW@186801|Clostridia,261VB@186807|Peptococcaceae 186801|Clostridia L TIGRFAM Phage SPO1 DNA polymerase-related protein - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k59_61588_2 1219035.NT2_13_00600 6.77e-39 144.0 290X3@1|root,2ZNIW@2|Bacteria,1P7TA@1224|Proteobacteria,2UXFQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_70508_1 1692242.A0A0K1RKZ2_9CIRC 1.54e-28 116.0 4QFEW@10239|Viruses,4QUKZ@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_103525_1 1316932.MHH_c17930 5.51e-19 91.3 COG3567@1|root,COG3567@2|Bacteria,1R45U@1224|Proteobacteria,1RY7G@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF1073) - - - ko:K09961 - - - - ko00000 - - - DUF1073 k59_261512_1 279238.Saro_2987 5.24e-119 355.0 2CYA9@1|root,32T3V@2|Bacteria,1RGRN@1224|Proteobacteria,2U90D@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_153863_1 77856.REP_BFDV 9.2e-18 89.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_94958_1 1379722.S5SY31_9CIRC 3.87e-78 243.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_61599_1 1230476.C207_01170 4.65e-13 70.1 2E4HT@1|root,32ZCW@2|Bacteria,1R6TI@1224|Proteobacteria,2VGSX@28211|Alphaproteobacteria,3JXYD@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_103721_2 1174684.EBMC1_07960 6.36e-06 52.8 COG5283@1|root,COG5412@1|root,COG5283@2|Bacteria,COG5412@2|Bacteria,1NFKU@1224|Proteobacteria,2U36H@28211|Alphaproteobacteria,2K1PU@204457|Sphingomonadales 204457|Sphingomonadales D Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_245009_1 1230342.CTM_16212 1.31e-07 58.2 COG0210@1|root,COG0210@2|Bacteria,1TPVG@1239|Firmicutes,2484I@186801|Clostridia,36E59@31979|Clostridiaceae 186801|Clostridia L helicase - - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k59_79699_3 691965.D4P7I8_9CAUD 2.16e-08 54.3 4QGJH@10239|Viruses,4QZ35@35237|dsDNA viruses no RNA stage,4QRZS@28883|Caudovirales,4QMAA@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_179529_5 105154.Q9MBU6_9VIRU 5.22e-72 235.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_253438_1 390874.Tpet_0640 0.000131 49.3 COG3507@1|root,COG3507@2|Bacteria 2|Bacteria G Belongs to the glycosyl hydrolase 43 family - - - - - - - - - - - - Glyco_hydro_43,Laminin_G_3,RicinB_lectin_2 k59_222401_2 1618237.A0A0C5IMG6_9CIRC 3.18e-09 64.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_62610_1 1408428.JNJP01000003_gene3493 6.34e-54 177.0 COG0270@1|root,COG0270@2|Bacteria 2|Bacteria L DNA (cytosine-5-)-methyltransferase activity - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_195541_2 360911.EAT1b_0041 3.27e-08 64.3 COG5280@1|root,COG5283@1|root,COG5280@2|Bacteria,COG5283@2|Bacteria,1UHQM@1239|Firmicutes,4ITE3@91061|Bacilli 91061|Bacilli M Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_188202_1 1173025.GEI7407_1172 8.67e-85 265.0 COG1089@1|root,COG1089@2|Bacteria,1G0M4@1117|Cyanobacteria,1H6XT@1150|Oscillatoriales 1117|Cyanobacteria M Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose gmd - 4.2.1.47 ko:K01711 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R00888 RC00402 ko00000,ko00001,ko01000 - - - GDP_Man_Dehyd k59_114958_1 1618247.A0A0C5I2K0_9CIRC 6.85e-17 82.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_63464_2 1788452.A0A190WHG0_9CIRC 7.74e-32 122.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_123217_2 1234888.K0A2J2_9VIRU 7.7e-31 120.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_180594_1 911008.GLAD_00750 1.13e-06 52.4 COG0270@1|root,COG0270@2|Bacteria,1MV9H@1224|Proteobacteria,1RPSH@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase,Dam,MethyltransfD12 k59_131491_1 294631.Q5ZGB2_9CAUD 1.09e-06 55.5 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_163607_2 348824.LPU83_1721 1.03e-112 353.0 COG0507@1|root,COG0507@2|Bacteria,1R1AT@1224|Proteobacteria,2U1ZX@28211|Alphaproteobacteria,4BAYZ@82115|Rhizobiaceae 28211|Alphaproteobacteria L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD - - - - - - - - - - - - Terminase_6 k59_96858_2 290398.Csal_1383 1.36e-08 57.8 2DT26@1|root,33IBU@2|Bacteria,1NNDF@1224|Proteobacteria,1SSB3@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4376) - - - - - - - - - - - - DUF4376 k59_22243_1 349161.Dred_2616 1e-49 182.0 COG1061@1|root,COG1061@2|Bacteria,1TQ62@1239|Firmicutes,249TK@186801|Clostridia,2622J@186807|Peptococcaceae 186801|Clostridia L type III restriction enzyme, res subunit - - - - - - - - - - - - HNH,Helicase_C,ResIII k59_22243_2 1454004.AW11_00908 6.88e-36 136.0 COG4643@1|root,COG4643@2|Bacteria,1MW9E@1224|Proteobacteria,2VKFM@28216|Betaproteobacteria 28216|Betaproteobacteria S P4 alpha zinc-binding domain protein - - - ko:K06919 - - - - ko00000 - - - Prim_Zn_Ribbon,Toprim_3 k59_72969_4 665950.HMPREF1025_01581 1.74e-28 127.0 COG5362@1|root,COG5362@2|Bacteria,1TSQB@1239|Firmicutes,24ACE@186801|Clostridia 186801|Clostridia S TIGRFAM Phage - - - - - - - - - - - - - k59_254404_2 745776.DGo_CA1893 1.13e-41 160.0 COG4653@1|root,COG4653@2|Bacteria 2|Bacteria G Phage capsid family xkdG - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_254404_3 760192.Halhy_0673 2.96e-35 128.0 COG4122@1|root,COG4122@2|Bacteria 2|Bacteria E O-methyltransferase activity - - - - - - - - - - - - Glycos_transf_2,Methyltransf_24 k59_254404_4 1224746.B932_1151 0.000779 47.0 2E5T9@1|root,330HK@2|Bacteria,1N9RB@1224|Proteobacteria,2UHDB@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - Sulfotransfer_2 k59_7617_2 762903.Pedsa_3355 3.88e-26 114.0 COG3866@1|root,COG3866@2|Bacteria,4P09P@976|Bacteroidetes,1IP71@117747|Sphingobacteriia 976|Bacteroidetes G Pectate lyase - - - - - - - - - - - - - k59_80747_2 743721.Psesu_1130 3.03e-109 328.0 28KIJ@1|root,2ZA3S@2|Bacteria,1R4PD@1224|Proteobacteria,1SKVF@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_80747_3 55601.VANGNB10_cI1638 1.47e-58 195.0 COG2404@1|root,COG2404@2|Bacteria,1MXEH@1224|Proteobacteria,1SADM@1236|Gammaproteobacteria 1236|Gammaproteobacteria S phosphoesterase DHHA1 - - - - - - - - - - - - DHHA1 k59_115905_1 398578.Daci_1953 8.62e-38 150.0 28S81@1|root,2ZEJD@2|Bacteria,1RCNN@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_115905_2 665942.HMPREF1022_02678 6.49e-05 44.3 2EHY9@1|root,33BPQ@2|Bacteria,1NGN4@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_97540_3 1477404.A0A023NFX4_9CAUD 1.01e-165 524.0 4QAXA@10239|Viruses,4QYJI@35237|dsDNA viruses no RNA stage,4QQ1A@28883|Caudovirales,4QNU7@10744|Podoviridae 10744|Podoviridae S metallopeptidase activity - - - - - - - - - - - - - k59_124177_1 1385658.U5KPZ6_9VIRU 1e-97 301.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_81602_1 186617.M9M8L2_9VIRU 5.35e-61 202.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_164579_1 1385658.U5KNR1_9VIRU 3.16e-34 130.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_124179_1 1385658.U5KPZ6_9VIRU 9.25e-65 214.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_132179_2 1609634.A0A0C5AFT2_9VIRU 3.22e-50 171.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_238407_1 1236541.BALL01000003_gene482 5.45e-30 117.0 COG3501@1|root,COG3501@2|Bacteria 2|Bacteria T Rhs element vgr protein - - - ko:K11910 - M00334 - - ko00000,ko00002,ko02044 3.A.23.1 - - AHH,PT-TG,Phage_GPD k59_173936_1 1385658.U5KPZ6_9VIRU 2.42e-44 159.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_33071_2 691965.D4P7D6_9CAUD 4.44e-58 199.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_231251_1 1122201.AUAZ01000017_gene2950 1.06e-42 158.0 COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,1RY1X@1236|Gammaproteobacteria,46BED@72275|Alteromonadaceae 1236|Gammaproteobacteria S associated with various cellular activities - - - - - - - - - - - - AAA,AAA_5 k59_64325_2 644282.Deba_3281 4.32e-17 82.4 COG4695@1|root,COG4695@2|Bacteria,1MUP5@1224|Proteobacteria,42MDD@68525|delta/epsilon subdivisions,2WWZC@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Phage portal protein - - - - - - - - - - - - Phage_portal k59_239958_1 1500301.JQMF01000006_gene1755 1.21e-20 92.0 28MSK@1|root,2ZB0X@2|Bacteria,1R7CY@1224|Proteobacteria,2U2MY@28211|Alphaproteobacteria,4BJ92@82115|Rhizobiaceae 28211|Alphaproteobacteria S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_256805_1 1038858.AXBA01000002_gene3781 2.73e-45 167.0 COG4676@1|root,COG4676@2|Bacteria,1NATM@1224|Proteobacteria 1224|Proteobacteria S Protein conserved in bacteria - - - - - - - - - - - - - k59_215120_1 439235.Dalk_4556 4.02e-17 83.2 28MVD@1|root,2ZB2Y@2|Bacteria,1R8NK@1224|Proteobacteria,42QIP@68525|delta/epsilon subdivisions,2WKTY@28221|Deltaproteobacteria,2MME2@213118|Desulfobacterales 28221|Deltaproteobacteria S Protein of unknown function (DUF4043) - - - - - - - - - - - - DUF4043 k59_198763_1 156889.Mmc1_1716 0.000237 48.5 28NGF@1|root,2ZBII@2|Bacteria,1R9KY@1224|Proteobacteria,2U1P7@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_41282_1 691965.D4P7D6_9CAUD 3.37e-54 189.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_239967_2 1524880.A0A076G697_9VIRU 2.68e-08 63.5 4QD1M@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_65691_1 1217658.F987_00327 2.32e-22 95.9 COG3772@1|root,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,1SA7C@1236|Gammaproteobacteria,3NSKU@468|Moraxellaceae 1236|Gammaproteobacteria G Phage lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - PG_binding_1,Phage_lysozyme k59_256821_1 1038858.AXBA01000020_gene4626 0.000973 45.8 COG4695@1|root,COG4695@2|Bacteria,1MUP5@1224|Proteobacteria,2TRFR@28211|Alphaproteobacteria,3EZC7@335928|Xanthobacteraceae 28211|Alphaproteobacteria S Phage portal protein - - - - - - - - - - - - Phage_portal k59_248368_1 1174528.JH992888_gene221 7.97e-05 48.5 COG1192@1|root,COG1192@2|Bacteria,1G56I@1117|Cyanobacteria 1117|Cyanobacteria D PFAM CobQ CobB MinD ParA nucleotide binding domain - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 k59_240272_1 411460.RUMTOR_01356 2.07e-60 213.0 28JED@1|root,2Z98K@2|Bacteria,1TW1U@1239|Firmicutes,24CFD@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - GerE k59_99089_1 795666.MW7_1046 7.95e-15 79.7 COG4733@1|root,COG4733@2|Bacteria,1MXB4@1224|Proteobacteria,2VJS7@28216|Betaproteobacteria 28216|Betaproteobacteria M Putative phage tail protein - - - - - - - - - - - - Phage-tail_3 k59_265084_2 1379709.S5TMV0_9CIRC 3.96e-30 122.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_257044_2 357276.EL88_08305 3.55e-06 50.4 COG3108@1|root,COG3108@2|Bacteria,4NW30@976|Bacteroidetes,2FSX2@200643|Bacteroidia,4AR8E@815|Bacteroidaceae 976|Bacteroidetes S Peptidase M15 - - - - - - - - - - - - Peptidase_M15_3 k59_89924_1 1219035.NT2_13_00580 2.24e-48 172.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_107597_1 371042.NG99_26210 5.6e-198 577.0 COG3740@1|root,COG4653@1|root,COG3740@2|Bacteria,COG4653@2|Bacteria,1Q3BS@1224|Proteobacteria,1S17W@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage capsid family - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_248378_2 1261131.lam_490 4.62e-13 70.9 COG5565@1|root,COG5565@2|Bacteria,1R6R3@1224|Proteobacteria,2U1P9@28211|Alphaproteobacteria,4BDQ9@82115|Rhizobiaceae 28211|Alphaproteobacteria S DNA packaging protein gp2 gp2 - - - - - - - - - - - Terminase_6,Terminase_6C k59_75183_2 1609634.A0A0C5AFV4_9VIRU 3.09e-269 750.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_257631_2 439235.Dalk_4601 6.06e-25 99.8 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,42TV9@68525|delta/epsilon subdivisions,2WNAN@28221|Deltaproteobacteria,2MKNW@213118|Desulfobacterales 28221|Deltaproteobacteria L Single-stranded DNA-binding protein ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_83430_2 716928.AJQT01000109_gene1217 4.06e-52 169.0 2FEUE@1|root,346TC@2|Bacteria,1MZPB@1224|Proteobacteria,2UC4Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_224506_3 1609634.A0A0C5AFV4_9VIRU 4.8e-196 565.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_224506_4 1609634.A0A0C5ANA6_9VIRU 3.6e-06 54.7 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_224506_7 1385658.U5KNR1_9VIRU 2.74e-44 160.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_249326_1 1618247.A0A0C5IMK7_9CIRC 4.2e-10 65.5 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_58608_2 1232452.BAIB02000007_gene1645 2.68e-19 85.5 2C6KN@1|root,32Y69@2|Bacteria,1VANX@1239|Firmicutes,24MNG@186801|Clostridia,26CAP@186813|unclassified Clostridiales 186801|Clostridia S VRR_NUC - - - - - - - - - - - - VRR_NUC k59_141617_1 1385658.U5KPZ6_9VIRU 6.69e-77 253.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_141617_3 105154.Q9MBU0_9VIRU 4e-51 179.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_141617_7 105154.Q9MBU6_9VIRU 2e-58 199.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_241033_1 1485543.JMME01000020_gene792 3.95e-10 61.6 COG0507@1|root,COG0507@2|Bacteria,1TQWH@1239|Firmicutes,4H656@909932|Negativicutes 909932|Negativicutes L Terminase RNaseH-like domain - - - - - - - - - - - - - k59_166470_1 999419.HMPREF1077_01869 6.85e-21 98.2 COG3378@1|root,COG3378@2|Bacteria,4NE1A@976|Bacteroidetes,2FPTD@200643|Bacteroidia 976|Bacteroidetes S Psort location Cytoplasmic, score 8.96 - - - - - - - - - - - - - k59_199638_1 935261.JAGL01000009_gene1165 4.89e-37 139.0 COG0209@1|root,COG0209@2|Bacteria,1PM78@1224|Proteobacteria,2UZUM@28211|Alphaproteobacteria,43QGW@69277|Phyllobacteriaceae 28211|Alphaproteobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides - - - - - - - - - - - - - k59_257744_2 1141519.H6VUA7_9CAUD 1.5e-82 282.0 4QBMV@10239|Viruses,4QUU6@35237|dsDNA viruses no RNA stage,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_656_1 186617.M9M8L2_9VIRU 1.66e-86 272.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_658_1 1788444.A0A190WHB9_9CIRC 5.2e-09 58.5 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_17429_2 1548905.A0A0A1IX16_9CAUD 5.06e-43 151.0 4QBTT@10239|Viruses,4QQUU@28883|Caudovirales,4QKWB@10699|Siphoviridae 10699|Siphoviridae S Phage conserved hypothetical protein BR0599 - - - - - - - - - - - - - k59_75846_1 1609634.A0A0C5AFV4_9VIRU 2.26e-104 323.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_75846_2 1609634.A0A0C5ANA6_9VIRU 1.84e-15 80.5 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_216982_1 1122201.AUAZ01000017_gene2950 1.15e-71 230.0 COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,1RY1X@1236|Gammaproteobacteria,46BED@72275|Alteromonadaceae 1236|Gammaproteobacteria S associated with various cellular activities - - - - - - - - - - - - AAA,AAA_5 k59_241527_2 1197951.I6S2A3_9CAUD 1.5e-23 101.0 4QAIV@10239|Viruses,4QYFZ@35237|dsDNA viruses no RNA stage,4QQUY@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_9366_1 1498011.A0A096XUX6_9CAUD 2.55e-176 520.0 4QCZC@10239|Viruses,4QRH3@28883|Caudovirales 28883|Caudovirales S Bacterial DNA polymerase III alpha subunit - - - - - - - - - - - - - k59_59108_1 1234888.K0A2J2_9VIRU 4.47e-58 197.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_167097_3 1692252.A0A0K1RL35_9CIRC 9.51e-72 230.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_191664_1 428125.CLOLEP_01379 1.51e-36 134.0 COG0553@1|root,COG0553@2|Bacteria,1TS9W@1239|Firmicutes,24CGX@186801|Clostridia,3WN6X@541000|Ruminococcaceae 186801|Clostridia KL Helicase conserved C-terminal domain - - - - - - - - - - - - - k59_67454_1 490913.C4NTE3_9CAUD 3.22e-33 129.0 4QFFI@10239|Viruses,4R00C@35237|dsDNA viruses no RNA stage,4QRHK@28883|Caudovirales,4QNX0@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_67454_2 490913.C4NTE2_9CAUD 2.99e-33 121.0 4QG5J@10239|Viruses,4QZ68@35237|dsDNA viruses no RNA stage,4QUEU@28883|Caudovirales,4QNKE@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_175111_1 1434319.W5RV68_9CAUD 4.22e-11 65.1 4QBHW@10239|Viruses,4QW8N@35237|dsDNA viruses no RNA stage,4QTT7@28883|Caudovirales,4QN92@10699|Siphoviridae 10699|Siphoviridae S sequence-specific DNA binding transcription factor activity - - - - - - - - - - - - - k59_191746_1 323098.Nwi_1182 3.27e-33 139.0 2DXK1@1|root,345BZ@2|Bacteria,1NC0U@1224|Proteobacteria,2UGGZ@28211|Alphaproteobacteria,3K1EQ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_225870_17 1160721.RBI_I01241 3.23e-53 186.0 COG0270@1|root,COG0270@2|Bacteria,1TS3G@1239|Firmicutes,249Q9@186801|Clostridia,3WH3U@541000|Ruminococcaceae 186801|Clostridia H Psort location Cytoplasmic, score dcm - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_259117_1 2003327.CAPSD_BPCHP 5.15e-73 249.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_109534_2 713587.THITH_04235 4.85e-21 99.0 COG4424@1|root,COG4424@2|Bacteria,1N77D@1224|Proteobacteria,1SB49@1236|Gammaproteobacteria,1WZDB@135613|Chromatiales 135613|Chromatiales S PFAM sulfotransferase - - - - - - - - - - - - Sulfotransfer_3 k59_118229_2 1522072.IL54_1284 2.03e-66 213.0 COG4974@1|root,COG4974@2|Bacteria,1QUTD@1224|Proteobacteria,2TW6U@28211|Alphaproteobacteria,2K7FW@204457|Sphingomonadales 204457|Sphingomonadales L Phage integrase family - - - - - - - - - - - - Phage_integrase k59_101406_1 151528.Q8W709_9CAUD 2.73e-20 90.5 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_101406_2 1158150.KB906242_gene236 2.56e-81 247.0 COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,1SQ0T@1236|Gammaproteobacteria 1236|Gammaproteobacteria L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_159138_2 2003327.CAPSD_BPCHP 5.45e-09 56.6 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_43579_1 1121344.JHZO01000006_gene1818 2.9e-25 106.0 28MKK@1|root,2ZAWR@2|Bacteria,1UYAT@1239|Firmicutes,24GI2@186801|Clostridia,3WR2E@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - RNA_helicase,Viral_Rep k59_218032_1 420324.KI911961_gene1745 6.35e-16 80.1 2CK39@1|root,32SBG@2|Bacteria,1MZ6F@1224|Proteobacteria,2UBT5@28211|Alphaproteobacteria,1JR6I@119045|Methylobacteriaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - Phage_connect_1 k59_126608_1 935261.JAGL01000009_gene1162 3.02e-26 111.0 28MSK@1|root,2ZB0X@2|Bacteria,1R7CY@1224|Proteobacteria,2U2MY@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_68175_2 864051.BurJ1DRAFT_0564 4.91e-15 71.6 2EBPV@1|root,335PY@2|Bacteria,1NK03@1224|Proteobacteria,2VY2U@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - DUF1360 k59_101415_1 437329.A5A3U1_9CAUD 5.83e-13 70.1 4QD1E@10239|Viruses,4QZVF@35237|dsDNA viruses no RNA stage,4QQTH@28883|Caudovirales,4QN2P@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_77498_2 1009370.ALO_12356 1.45e-36 144.0 28MVD@1|root,2ZB2Y@2|Bacteria,1VR3R@1239|Firmicutes,4H760@909932|Negativicutes 909932|Negativicutes S Protein of unknown function (DUF4043) - - - - - - - - - - - - DUF4043 k59_260109_1 879308.HMPREF9130_0662 1.17e-30 127.0 COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,22FY9@1570339|Peptoniphilaceae 186801|Clostridia L DNA-directed DNA polymerase dnaE - 2.7.7.7 ko:K02337,ko:K14162 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k59_28028_1 1357732.A0A059PYD9_9CAUD 6.03e-10 65.5 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales,4QNBW@10744|Podoviridae 10744|Podoviridae S DNA helicase activity - - - - - - - - - - - - - k59_243157_2 1131814.JAFO01000001_gene2083 8.85e-10 61.6 COG0507@1|root,COG5362@1|root,COG0507@2|Bacteria,COG5362@2|Bacteria,1R90H@1224|Proteobacteria,2U236@28211|Alphaproteobacteria 28211|Alphaproteobacteria L TIGRFAM Phage - - - - - - - - - - - - Terminase_6 k59_10790_4 1264737.K9S139_9CAUD 5.6e-08 55.8 4QE7X@10239|Viruses,4QVF0@35237|dsDNA viruses no RNA stage,4QPUM@28883|Caudovirales,4QP17@10744|Podoviridae 10744|Podoviridae S Cytidine and deoxycytidylate deaminase zinc-binding region - - - - - - - - - - - - - k59_226857_1 1121889.AUDM01000004_gene2504 2.63e-78 254.0 28M0V@1|root,2ZAFR@2|Bacteria,4NKHG@976|Bacteroidetes,1I0C9@117743|Flavobacteriia,2NYCN@237|Flavobacterium 976|Bacteroidetes - - - - - - - - - - - - - - - k59_102361_1 1122929.KB908227_gene3147 1.78e-12 63.5 2EMA3@1|root,33EZ4@2|Bacteria,1NPI4@1224|Proteobacteria,2UNEC@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_119316_1 208439.AJAP_42485 4.41e-50 178.0 COG1783@1|root,COG1783@2|Bacteria 2|Bacteria S DNA packaging - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_6 k59_243160_1 1120797.KB908256_gene2031 2.59e-36 135.0 299CW@1|root,2ZWFT@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_35922_1 1453501.JELR01000001_gene2516 3.18e-55 195.0 COG4733@1|root,COG4926@1|root,COG4733@2|Bacteria,COG4926@2|Bacteria,1R77Q@1224|Proteobacteria,1S1WT@1236|Gammaproteobacteria,469QU@72275|Alteromonadaceae 1236|Gammaproteobacteria S Fibronectin type 3 domain - - - - - - - - - - - - - k59_60548_2 1234888.K0A2J2_9VIRU 7.53e-135 402.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_152529_1 1609634.A0A0C5ANA6_9VIRU 2.47e-26 105.0 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_93810_1 1235689.K4NWL6_9CAUD 2.62e-125 389.0 4QAY9@10239|Viruses,4QWGZ@35237|dsDNA viruses no RNA stage,4QRJC@28883|Caudovirales,4QP2W@10744|Podoviridae 10744|Podoviridae S DNA primase activity - - - - - - - - - - - - - k59_226869_2 258594.RPA2527 1.65e-51 180.0 COG5108@1|root,COG5108@2|Bacteria,1PIWB@1224|Proteobacteria,2U1JR@28211|Alphaproteobacteria 28211|Alphaproteobacteria K DNA-dependent RNA polymerase - - - - - - - - - - - - RNA_pol,RPOL_N k59_119326_1 1609634.A0A0C5AFV4_9VIRU 2.86e-39 152.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_219230_2 596327.PORUE0001_1194 6.65e-28 111.0 COG0270@1|root,COG0270@2|Bacteria,4NG9A@976|Bacteroidetes,2FR60@200643|Bacteroidia 976|Bacteroidetes H Cytosine-specific methyltransferase dcm - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_35925_1 78398.KS43_20360 1.77e-20 91.7 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,1RR0M@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_35925_2 78398.KS43_20365 3.91e-20 87.8 28RDB@1|root,2ZDSP@2|Bacteria,1RBF9@1224|Proteobacteria,1RQ0W@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - Tube k59_28190_1 1618237.A0A0C5IMG6_9CIRC 6.71e-26 112.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_152533_1 237609.PSAKL28_31470 1.58e-57 186.0 COG1961@1|root,COG1961@2|Bacteria,1R3XB@1224|Proteobacteria,1RSC2@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Resolvase - - - - - - - - - - - - HTH_7,Resolvase k59_18945_1 1618236.A0A0C5IB23_9CIRC 1.97e-26 115.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_203207_2 220341.16502955 2.41e-27 105.0 2C4D9@1|root,337PW@2|Bacteria,1NE4W@1224|Proteobacteria,1SGM1@1236|Gammaproteobacteria,3ZMCR@590|Salmonella 1236|Gammaproteobacteria S Protein of unknown function (DUF1353) - - - - - - - - - - - - DUF1353 k59_161370_1 997884.HMPREF1068_03186 2.99e-16 85.5 COG1783@1|root,COG1783@2|Bacteria,4NHPB@976|Bacteroidetes,2FR95@200643|Bacteroidia,4AP7A@815|Bacteroidaceae 976|Bacteroidetes S Phage terminase, large subunit, PBSX family - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C k59_252216_1 1035191.HMPREF0185_02750 9.52e-05 48.5 COG0582@1|root,COG0582@2|Bacteria,1RD46@1224|Proteobacteria,2U7Q0@28211|Alphaproteobacteria 28211|Alphaproteobacteria L COG0582 Integrase - - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_integrase k59_228077_3 312309.VF_2017 2.27e-41 140.0 2CPEB@1|root,32SIW@2|Bacteria,1MZE0@1224|Proteobacteria,1SARU@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_61435_1 1548905.A0A0A1IV72_9CAUD 3.73e-31 132.0 4QBQM@10239|Viruses,4QPZ5@28883|Caudovirales,4QMBJ@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_120504_1 1673638.A0A0H4AJL5_9CIRC 1.85e-09 62.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_29320_2 1003195.SCAT_0615 2.74e-36 133.0 28MC2@1|root,2ZAQD@2|Bacteria,2IKMZ@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_137203_1 112098.XP_008604358.1 4.9e-09 58.2 2E0C0@1|root,2S7SW@2759|Eukaryota 2759|Eukaryota - - - - - - - - - - - - - - - k59_194375_1 1692259.A0A0K1RL59_9CIRC 6.19e-09 56.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_37078_1 1385658.U5KPZ6_9VIRU 7.93e-190 547.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_37078_3 1385658.U5KNR1_9VIRU 1.56e-70 229.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_94965_2 1236000.L0AQZ2_9CAUD 8.23e-41 141.0 4QEGD@10239|Viruses,4QVU1@35237|dsDNA viruses no RNA stage,4QPN9@28883|Caudovirales,4QJCM@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_178358_1 1307834.BARL01000002_gene1210 9.9e-30 119.0 COG4653@1|root,COG4653@2|Bacteria,1MWU1@1224|Proteobacteria,2VF2A@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Phage capsid family - - - - - - - - - - - - Phage_capsid k59_235883_2 864565.HMPREF0379_1469 5.09e-30 119.0 COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,247ZJ@186801|Clostridia,25QQ0@186804|Peptostreptococcaceae 186801|Clostridia T Psort location Cytoplasmic, score phoH - - ko:K06217 - - - - ko00000 - - - PhoH k59_203751_1 1385658.U5KPZ6_9VIRU 5.3e-36 136.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_261809_1 1449351.RISW2_21990 4.62e-17 85.9 COG0740@1|root,COG0740@2|Bacteria,1MUQ9@1224|Proteobacteria,2U37W@28211|Alphaproteobacteria 28211|Alphaproteobacteria OU Belongs to the peptidase S14 family - - - - - - - - - - - - CLP_protease k59_5285_2 428125.CLOLEP_01409 3.47e-90 281.0 COG4626@1|root,COG4626@2|Bacteria,1TT9I@1239|Firmicutes,24AFK@186801|Clostridia,3WNF4@541000|Ruminococcaceae 186801|Clostridia S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_235888_1 1287116.X734_06060 7.31e-15 76.3 COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,1MVH7@1224|Proteobacteria,2TRNA@28211|Alphaproteobacteria,43HY9@69277|Phyllobacteriaceae 28211|Alphaproteobacteria KL Belongs to the N(4) N(6)-methyltransferase family - - - - - - - - - - - - N6_N4_Mtase,ParBc k59_235888_2 460265.Mnod_6996 4.16e-22 91.7 2DS0Z@1|root,33E0M@2|Bacteria,1NIVH@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_137484_1 1168547.L7P648_9CIRC 1.24e-36 140.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_194689_1 1123288.SOV_2c10440 1.02e-55 189.0 COG0553@1|root,COG0553@2|Bacteria,1TP2C@1239|Firmicutes,4H2V4@909932|Negativicutes 909932|Negativicutes KL DEAD-like helicases superfamily - - - - - - - - - - - - N6_N4_Mtase k59_194689_2 1120971.AUCA01000053_gene371 2.26e-67 213.0 COG0863@1|root,COG0863@2|Bacteria,1UZIN@1239|Firmicutes,4HU16@91061|Bacilli 91061|Bacilli L DNA methylase - - - - - - - - - - - - N6_N4_Mtase k59_228802_1 691965.D4P7I3_9CAUD 8.85e-96 313.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_221524_1 1307761.L21SP2_1299 4.95e-93 299.0 COG0209@1|root,COG0209@2|Bacteria 2|Bacteria F ribonucleoside-diphosphate reductase activity rtpR - 1.1.98.6,1.17.4.1 ko:K00525,ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024,R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,LAGLIDADG_3,Ribonuc_red_lgC k59_171081_1 387092.NIS_0468 2.41e-30 122.0 2BF3Y@1|root,315AZ@2|Bacteria,1NCT0@1224|Proteobacteria,42Y21@68525|delta/epsilon subdivisions 1224|Proteobacteria - - - - - - - - - - - - - - DUF4055 k59_113143_1 1520935.A0A0H3UB63_9CIRC 2.58e-47 166.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_244587_1 1234888.K0A2J2_9VIRU 2.36e-67 221.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_79204_1 335283.Neut_1455 1.1e-76 258.0 COG2304@1|root,COG4733@1|root,COG2304@2|Bacteria,COG4733@2|Bacteria,1MXB4@1224|Proteobacteria,2VJS7@28216|Betaproteobacteria 28216|Betaproteobacteria M Putative phage tail protein - - - - - - - - - - - - Phage-tail_3 k59_211324_1 1385658.U5KPZ6_9VIRU 3.39e-101 313.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_154422_4 153948.NAL212_2011 0.000342 47.8 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase - - - - - - - - - - - - Methyltransf_11 k59_252858_1 1197951.I6S2A3_9CAUD 9.4e-42 149.0 4QAIV@10239|Viruses,4QYFZ@35237|dsDNA viruses no RNA stage,4QQUY@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_71063_2 457398.HMPREF0326_03042 4.72e-27 110.0 2CWYZ@1|root,32T0P@2|Bacteria,1MZEM@1224|Proteobacteria,4337C@68525|delta/epsilon subdivisions,2WXPD@28221|Deltaproteobacteria,2MCUC@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_72580_2 444875.E3SMD8_9CAUD 1.4e-70 217.0 4QD0J@10239|Viruses,4R0A5@35237|dsDNA viruses no RNA stage,4QSK9@28883|Caudovirales,4QNR4@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_196077_3 316067.Geob_0663 7.24e-18 89.0 COG1091@1|root,COG1091@2|Bacteria,1MUXM@1224|Proteobacteria,42MGE@68525|delta/epsilon subdivisions,2WKQ9@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose - - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind k59_196077_4 1120746.CCNL01000014_gene2162 5.67e-17 84.3 COG0399@1|root,COG0399@2|Bacteria,2NQAE@2323|unclassified Bacteria 2|Bacteria M DegT/DnrJ/EryC1/StrS aminotransferase family rfbH - 1.17.1.1,4.2.1.164 ko:K12452,ko:K13328 ko00520,ko00523,ko01130,map00520,map00523,map01130 M00802 R03391,R03392,R08930 RC00230,RC00704 ko00000,ko00001,ko00002,ko01000 - - - DegT_DnrJ_EryC1 k59_7137_2 31535.D4FUM0_BPD3 4.34e-09 59.7 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_180181_1 1692250.A0A0K1RLR1_9CIRC 1.15e-48 165.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_254043_2 69279.BG36_20805 1.6e-31 134.0 2AA25@1|root,30ZAV@2|Bacteria,1PM8F@1224|Proteobacteria,2UZVR@28211|Alphaproteobacteria,43QIT@69277|Phyllobacteriaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_7141_2 1555202.A0A097EX03_9CAUD 2.27e-06 50.1 4QHMD@10239|Viruses,4QRG7@28883|Caudovirales,4QIFJ@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_196086_1 438482.A4ZRC7_9CAUD 1.7e-13 70.9 4QNBD@10744|Podoviridae 10744|Podoviridae S outer membrane - - - - - - - - - - - - - k59_263300_1 1609634.A0A0C5ANA6_9VIRU 2.92e-17 83.2 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_21787_1 582899.Hden_0147 2.4e-21 92.0 2DP75@1|root,330U8@2|Bacteria,1N8XA@1224|Proteobacteria,2UIHW@28211|Alphaproteobacteria 28211|Alphaproteobacteria L PFAM Pathogenesis-related transcriptional factor and ERF protein - - - - - - - - - - - - AP2,HNH_3 k59_114678_1 1166948.JPZL01000002_gene1845 1.8e-61 200.0 28W6R@1|root,2ZI7D@2|Bacteria,1N49N@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_105415_1 1609634.A0A0C5AFV4_9VIRU 5.55e-157 463.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_22027_2 444158.MmarC6_0019 1.12e-09 58.5 COG0863@1|root,arCOG00115@2157|Archaea,2XWB2@28890|Euryarchaeota,23RT5@183939|Methanococci 183939|Methanococci L PFAM DNA methylase N-4 N-6 domain protein - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_87815_1 2003327.CAPSD_BPCHP 7.51e-68 229.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_87815_2 1609634.A0A0C5ANA6_9VIRU 3.26e-08 60.5 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_100048_1 1609634.A0A0C5AFV4_9VIRU 1.67e-55 190.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_108337_1 2003327.CAPSD_BPCHP 1.27e-23 105.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_241008_2 439292.Bsel_3009 1.75e-42 170.0 COG3780@1|root,COG4626@1|root,COG3780@2|Bacteria,COG4626@2|Bacteria,1TPU1@1239|Firmicutes,4HAXI@91061|Bacilli,26PJM@186821|Sporolactobacillaceae 91061|Bacilli L Phage Terminase - - - - - - - - - - - - Terminase_1 k59_50270_3 145579.CAPSD_BPPHM 1.19e-24 107.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_232770_3 1209989.TepiRe1_1126 8.75e-05 46.2 2C9JF@1|root,32RPD@2|Bacteria,1VC16@1239|Firmicutes,24RAH@186801|Clostridia,42IR8@68295|Thermoanaerobacterales 186801|Clostridia S ERF superfamily - - - - - - - - - - - - ERF k59_158039_1 755732.Fluta_0717 6.4e-06 52.0 COG2520@1|root,COG2520@2|Bacteria,4NVH3@976|Bacteroidetes,1IKD5@117743|Flavobacteriia 976|Bacteroidetes J Methyltransferase FkbM domain - - - - - - - - - - - - Methyltransf_21 k59_42038_1 1556290.A0A0A0RQH0_9CAUD 2.68e-58 232.0 4QAK6@10239|Viruses,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_75364_3 1051985.l11_04450 1.06e-17 77.4 COG3926@1|root,COG3926@2|Bacteria,1MVXW@1224|Proteobacteria,2VRGU@28216|Betaproteobacteria,2KR8T@206351|Neisseriales 206351|Neisseriales S Glycosyl hydrolase 108 - - - - - - - - - - - - Glyco_hydro_108,PG_binding_3 k59_776_3 1379712.S5TMV9_9CIRC 6.4e-27 117.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_158172_1 1165094.RINTHH_3920 1.18e-60 201.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_232927_1 988656.F0V6Y5_9CAUD 2.96e-41 156.0 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales,4QNBW@10744|Podoviridae 10744|Podoviridae S DNA helicase activity - - - - - - - - - - - - - k59_150018_1 511062.GU3_16329 5.06e-34 124.0 COG1192@1|root,COG1192@2|Bacteria,1MWRE@1224|Proteobacteria,1RMZN@1236|Gammaproteobacteria,1Y67V@135624|Aeromonadales 135624|Aeromonadales D AAA domain - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 k59_100947_1 742740.HMPREF9474_02306 2.16e-11 67.0 2BPMG@1|root,32IEH@2|Bacteria,1V9DC@1239|Firmicutes,24MC0@186801|Clostridia,2227H@1506553|Lachnoclostridium 186801|Clostridia S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - - k59_100947_2 665950.HMPREF1025_01957 7.04e-193 590.0 2EWZQ@1|root,33QB0@2|Bacteria,1V0T1@1239|Firmicutes,249Z2@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_51272_1 316407.85674679 1.45e-25 107.0 COG1961@1|root,COG1961@2|Bacteria,1N6DV@1224|Proteobacteria,1RYWS@1236|Gammaproteobacteria,3XQ5U@561|Escherichia 1236|Gammaproteobacteria L recombinase activity ybcK - - - - - - - - - - - Recombinase,Resolvase,Zn_ribbon_recom k59_117760_1 1609634.A0A0C5AFT2_9VIRU 8.91e-24 104.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_158721_1 1692256.A0A0K1RL85_9CIRC 3.49e-24 100.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_150872_2 1477404.A0A023NGN9_9CAUD 1.96e-138 397.0 4QFP7@10239|Viruses,4QWTW@35237|dsDNA viruses no RNA stage,4QSRU@28883|Caudovirales,4QNWE@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - - - - - - - - - - - - - k59_200433_1 1165094.RINTHH_3920 6.42e-56 189.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_200433_3 1609634.A0A0C5AFV4_9VIRU 8.03e-156 462.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_191954_1 1123367.C666_04180 7.11e-55 202.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2VJ57@28216|Betaproteobacteria,2KUC6@206389|Rhodocyclales 206389|Rhodocyclales L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_92735_1 644107.SL1157_1663 2.64e-18 91.7 COG3087@1|root,COG3087@2|Bacteria,1QU07@1224|Proteobacteria,2TR07@28211|Alphaproteobacteria 28211|Alphaproteobacteria D peptidase U35 phage prohead HK97 u35 - - - - - - - - - - - Mu-like_gpT,Peptidase_S78 k59_258845_4 672.VV93_v1c15490 2.47e-10 60.5 2CK0Z@1|root,2ZGJP@2|Bacteria,1P8ZQ@1224|Proteobacteria,1ST78@1236|Gammaproteobacteria,1XZ80@135623|Vibrionales 135623|Vibrionales S CTX phage RstB protein - - - - - - - - - - - - CTX_RstB k59_258845_5 243277.VC_1454 4.28e-74 240.0 COG2946@1|root,COG2946@2|Bacteria,1RDKM@1224|Proteobacteria,1S46D@1236|Gammaproteobacteria,1XWA2@135623|Vibrionales 135623|Vibrionales L Replication initiation factor - - - ko:K07467 - - - - ko00000 - - - Rep_trans k59_1777_13 691965.D4P7E6_9CAUD 9.02e-09 66.6 4QAK6@10239|Viruses,4R01K@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_59463_4 225937.HP15_655 6.28e-16 79.3 COG4675@1|root,COG4675@2|Bacteria 2|Bacteria M tail collar domain protein - - - - - - - - - - - - Collar k59_258853_1 371731.Rsw2DRAFT_3036 1.61e-09 65.9 COG2304@1|root,COG2304@2|Bacteria,1QWI7@1224|Proteobacteria,2TY8F@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Putative phage tail protein - - - - - - - - - - - - Phage-tail_3,VWA k59_51373_1 1692256.A0A0K1RL85_9CIRC 3.22e-40 145.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_200438_1 1498011.A0A096XUV6_9CAUD 3.17e-60 190.0 4QB0T@10239|Viruses,4QPUT@28883|Caudovirales 28883|Caudovirales S Protein of unknown function (DUF669) - - - - - - - - - - - - - k59_200438_3 1498011.A0A096XUV8_9CAUD 7.43e-94 285.0 4QDKA@10239|Viruses,4QPPG@28883|Caudovirales 28883|Caudovirales S nuclease activity - - - - - - - - - - - - - k59_200438_4 1498011.A0A096XUV7_9CAUD 3.02e-98 302.0 4QB5I@10239|Viruses,4QPQ9@28883|Caudovirales,4QNX6@10744|Podoviridae 10744|Podoviridae S Helicase conserved C-terminal domain - - - - - - - - - - - - - k59_226423_11 102129.Lepto7375DRAFT_8238 1.6e-11 75.1 COG1404@1|root,COG1404@2|Bacteria,1G1G8@1117|Cyanobacteria,1H8EN@1150|Oscillatoriales 1117|Cyanobacteria O Subtilisin-like serine - - - ko:K14645 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - Peptidase_S8 k59_226423_29 742767.HMPREF9456_03368 1.05e-44 184.0 COG5280@1|root,COG5280@2|Bacteria,4PNYN@976|Bacteroidetes,2FPMT@200643|Bacteroidia 976|Bacteroidetes S domain protein - - - - - - - - - - - - - k59_226423_34 1122981.AUME01000026_gene530 1.68e-92 290.0 COG1783@1|root,COG1783@2|Bacteria,4PMA2@976|Bacteroidetes,2G2CX@200643|Bacteroidia 976|Bacteroidetes S Terminase RNAseH like domain - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C k59_226423_36 994573.T472_0210805 3.23e-66 225.0 COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,1TPHP@1239|Firmicutes,249MR@186801|Clostridia,36FKT@31979|Clostridiaceae 186801|Clostridia KL Belongs to the N(4) N(6)-methyltransferase family - - - - - - - - - - - - N6_N4_Mtase,ParBc k59_226423_39 445970.ALIPUT_02670 4.68e-06 52.8 2EAUN@1|root,334W9@2|Bacteria,4NW5Y@976|Bacteroidetes,2FU2N@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_176618_1 742733.HMPREF9469_05062 1.92e-69 223.0 COG0553@1|root,COG0553@2|Bacteria,1TS9W@1239|Firmicutes,24CGX@186801|Clostridia,222GT@1506553|Lachnoclostridium 186801|Clostridia KL Helicase conserved C-terminal domain - - - - - - - - - - - - - k59_110567_1 338473.A6XAD2_9CAUD 1.92e-60 204.0 4QAWD@10239|Viruses,4QVNG@35237|dsDNA viruses no RNA stage,4QQCM@28883|Caudovirales,4QNB7@10744|Podoviridae 10744|Podoviridae S nucleotide binding - - - - - - - - - - - - - k59_226565_1 465515.Mlut_14360 6.89e-36 132.0 COG1652@1|root,COG1652@2|Bacteria,2GK68@201174|Actinobacteria,1W98D@1268|Micrococcaceae 201174|Actinobacteria S Transglycosylase-like domain - - - ko:K21687,ko:K21691 - - - - ko00000 - GH23 - LysM,Transglycosylas k59_201646_1 1280944.HY17_04705 4.17e-06 57.0 2E8SI@1|root,3333B@2|Bacteria,1N7MG@1224|Proteobacteria,2UJSF@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_110568_2 1210884.HG799465_gene11670 7.25e-33 128.0 COG5362@1|root,COG5362@2|Bacteria,2J0FK@203682|Planctomycetes 203682|Planctomycetes S Terminase-like family - - - - - - - - - - - - Terminase_6 k59_192864_1 412597.AEPN01000059_gene3564 2.63e-35 140.0 COG3505@1|root,COG3505@2|Bacteria 412597.AEPN01000059_gene3564|- U unidirectional conjugation - - - - - - - - - - - - - k59_168784_2 10752.A0MZC0_BPN4 1.15e-57 190.0 4QAUS@10239|Viruses,4QURX@35237|dsDNA viruses no RNA stage,4QQ2S@28883|Caudovirales,4QNNP@10744|Podoviridae 10744|Podoviridae S flavin adenine dinucleotide binding - - - - - - - - - - - - - k59_44149_1 1234888.K0A2J2_9VIRU 6.67e-30 121.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_202851_1 1609634.A0A0C5AFV4_9VIRU 6.85e-102 312.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_243860_2 102129.Lepto7375DRAFT_4568 9.7e-50 169.0 2E6SC@1|root,331CE@2|Bacteria,1G9SF@1117|Cyanobacteria,1HD1F@1150|Oscillatoriales 1117|Cyanobacteria - - - - - - - - - - - - - - - k59_251943_1 446470.Snas_2893 5.19e-28 114.0 28HRJ@1|root,2Z7YZ@2|Bacteria,2GKNT@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_53843_3 411460.RUMTOR_02024 1.1e-11 67.0 2A0KC@1|root,30NQJ@2|Bacteria,1V3K4@1239|Firmicutes,24HYK@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_177854_1 1692255.A0A0K1RL52_9CIRC 1.08e-37 136.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_94537_1 268739.Nmlp_2675 1.41e-10 67.0 COG4983@1|root,arCOG06276@2157|Archaea,2XUG1@28890|Euryarchaeota,23SRM@183963|Halobacteria 183963|Halobacteria L Phage plasmid primase, P4 - - - ko:K06919 - - - - ko00000 - - - - k59_19709_1 1618254.A0A0C5IBG4_9CIRC 2.36e-101 301.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_19709_2 1676988.A0A0H4FV52_9CIRC 4.44e-19 93.2 4QGVY@10239|Viruses,4QUKN@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_186181_2 1121115.AXVN01000013_gene3168 1.71e-09 68.6 COG0739@1|root,COG0791@1|root,COG0739@2|Bacteria,COG0791@2|Bacteria,1TP24@1239|Firmicutes,247K5@186801|Clostridia,3XYSD@572511|Blautia 186801|Clostridia M Psort location Extracellular, score 9.55 - - - - - - - - - - - - NLPC_P60,Peptidase_M23 k59_210448_7 935261.JAGL01000009_gene1177 8.21e-59 214.0 COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1QT52@1224|Proteobacteria,2TVNI@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Toprim-like - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - DnaB_C,Toprim_2 k59_235226_1 753085.F4YCV3_9CAUD 1.15e-66 230.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_4469_1 1042209.HK44_020620 6.22e-41 145.0 2C377@1|root,2Z7II@2|Bacteria,1NNYY@1224|Proteobacteria,1RMDR@1236|Gammaproteobacteria 1236|Gammaproteobacteria S P22 coat protein - gene protein 5 - - - - - - - - - - - - P22_CoatProtein k59_4469_3 1122201.AUAZ01000010_gene2520 1.29e-41 148.0 29UKS@1|root,30FY7@2|Bacteria,1RGKW@1224|Proteobacteria,1SKMS@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_53856_1 102129.Lepto7375DRAFT_5434 2.23e-49 171.0 COG0568@1|root,COG0568@2|Bacteria,1G2FE@1117|Cyanobacteria,1H7ED@1150|Oscillatoriales 1117|Cyanobacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released sigE - - ko:K03086,ko:K03087 ko02026,ko05111,map02026,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 k59_244943_1 1217656.F964_00522 1.45e-12 71.6 COG2304@1|root,COG2304@2|Bacteria,1QWI7@1224|Proteobacteria,1T2VU@1236|Gammaproteobacteria,3NN2S@468|Moraxellaceae 1236|Gammaproteobacteria S Putative phage tail protein - - - - - - - - - - - - Phage-tail_3 k59_171536_1 1223545.GS4_51_00120 9.72e-36 132.0 2CJW6@1|root,32SAX@2|Bacteria,2ISQ9@201174|Actinobacteria,4GGDY@85026|Gordoniaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_253257_2 1234888.K0A2J2_9VIRU 1.68e-116 358.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_113684_1 172088.AUGA01000033_gene4625 2.76e-43 154.0 COG3170@1|root,COG3170@2|Bacteria,1R69E@1224|Proteobacteria,2U3B9@28211|Alphaproteobacteria 28211|Alphaproteobacteria NU Phage P22-like portal protein - - - - - - - - - - - - - k59_13049_5 1340829.S5Y5F0_9CAUD 1.1e-49 191.0 4QNA2@10699|Siphoviridae 10699|Siphoviridae S AAA domain - - - - - - - - - - - - - k59_79651_3 1609634.A0A0C5AFV4_9VIRU 5.26e-51 175.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_162455_5 526222.Desal_2558 2.67e-40 151.0 COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,42QA8@68525|delta/epsilon subdivisions,2WJBW@28221|Deltaproteobacteria,2M8NS@213115|Desulfovibrionales 28221|Deltaproteobacteria S PFAM ATPase associated with various cellular activities - - - - - - - - - - - - AAA_3,AAA_5 k59_138205_1 1384049.CD29_04855 3.87e-11 74.7 COG0739@1|root,COG3583@1|root,COG0739@2|Bacteria,COG3583@2|Bacteria,1TRWJ@1239|Firmicutes,4HB43@91061|Bacilli,3IXJZ@400634|Lysinibacillus 91061|Bacilli M membrane nlpD - - - - - - - - - - - G5,LysM,Peptidase_M23 k59_130350_1 231434.JQJH01000004_gene511 8.37e-09 60.5 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2TRJF@28211|Alphaproteobacteria,3NACC@45404|Beijerinckiaceae 28211|Alphaproteobacteria L DNA polymerase A domain polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_171543_1 186617.M9M8L2_9VIRU 1.59e-99 306.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_236517_1 1399915.X2CST8_9CAUD 3.75e-36 130.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QHVT@10662|Myoviridae 10662|Myoviridae S amidase activity - - - - - - - - - - - - - k59_37832_1 1500301.JQMF01000006_gene1755 6.33e-72 236.0 28MSK@1|root,2ZB0X@2|Bacteria,1R7CY@1224|Proteobacteria,2U2MY@28211|Alphaproteobacteria,4BJ92@82115|Rhizobiaceae 28211|Alphaproteobacteria S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_37832_2 935261.JAGL01000009_gene1160 1.09e-21 99.4 2DUXE@1|root,32UY2@2|Bacteria,1N2YI@1224|Proteobacteria,2UEWK@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Phage T7 capsid assembly protein - - - - - - - - - - - - Phage_T7_Capsid k59_262461_1 1121921.KB898706_gene3040 2.32e-26 114.0 28JKJ@1|root,2Z9DD@2|Bacteria,1MUN2@1224|Proteobacteria,1RQIP@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage P22-like portal protein - - - - - - - - - - - - P22_portal k59_30612_1 1618248.A0A0C5IB82_9CIRC 8.79e-61 202.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_113940_1 1528106.JRJE01000020_gene2289 6.15e-06 47.0 COG3773@1|root,COG3773@2|Bacteria,1RH3D@1224|Proteobacteria,2UAUQ@28211|Alphaproteobacteria,2JT2U@204441|Rhodospirillales 204441|Rhodospirillales M Cell Wall Hydrolase - - - - - - - - - - - - Hydrolase_2 k59_30902_1 1379709.S5TMV0_9CIRC 1.44e-09 59.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_113941_1 68219.JNXI01000060_gene2172 7.85e-19 88.2 2D784@1|root,32TNH@2|Bacteria,2GRDQ@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_147468_1 416870.llmg_2250 1.24e-05 46.6 COG3728@1|root,COG3728@2|Bacteria,1VAD9@1239|Firmicutes,4HKCF@91061|Bacilli,1YCHD@1357|Lactococcus 91061|Bacilli L Terminase small subunit - - - ko:K07474 - - - - ko00000 - - - Terminase_2 k59_171818_1 1548905.A0A0A1IUN7_9CAUD 3.65e-17 89.0 4QF9I@10239|Viruses,4QTTB@28883|Caudovirales,4QN6Q@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_171818_2 1133022.I6NTN2_9CAUD 4.16e-16 85.9 4QC7M@10239|Viruses,4QW2A@35237|dsDNA viruses no RNA stage,4QTDB@28883|Caudovirales,4QM7R@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_230270_3 688245.CtCNB1_1438 1.22e-54 178.0 28J67@1|root,2Z91Y@2|Bacteria,1R7RG@1224|Proteobacteria,2VRTM@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_56387_1 1297569.MESS2_1220034 1.86e-56 185.0 COG1442@1|root,COG1442@2|Bacteria,1QH4S@1224|Proteobacteria,2U9KQ@28211|Alphaproteobacteria,43JIY@69277|Phyllobacteriaceae 28211|Alphaproteobacteria M glycosyl transferase family 8 - - - - - - - - - - - - - k59_7449_1 1341679.P253_03096 2.21e-100 300.0 COG5527@1|root,COG5527@2|Bacteria,1RD9C@1224|Proteobacteria,1S4ZG@1236|Gammaproteobacteria,3NJHN@468|Moraxellaceae 1236|Gammaproteobacteria L Initiator Replication protein - - - - - - - - - - - - Rep_3 k59_123132_3 1173264.KI913949_gene1758 9.54e-07 59.7 COG3179@1|root,COG3772@1|root,COG3179@2|Bacteria,COG3772@2|Bacteria,1G6G1@1117|Cyanobacteria,1HB21@1150|Oscillatoriales 1117|Cyanobacteria S Chitinase class I - - - - - - - - - - - - DUF4231,Glyco_hydro_19,PG_binding_1 k59_123132_11 460265.Mnod_4233 2.04e-70 228.0 COG0468@1|root,COG0468@2|Bacteria,1PXGB@1224|Proteobacteria,2V21B@28211|Alphaproteobacteria,1JXXV@119045|Methylobacteriaceae 28211|Alphaproteobacteria L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage - - - - - - - - - - - - - k59_223576_1 105154.Q9MBU3_9VIRU 4.03e-08 58.2 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_237610_1 1437448.AZRT01000048_gene73 7.14e-14 75.9 2CYA9@1|root,32T3V@2|Bacteria,1RGRN@1224|Proteobacteria,2U90D@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_32085_2 1204526.K4HZ42_9CAUD 3.54e-19 86.7 4QC86@10239|Viruses,4QVG3@35237|dsDNA viruses no RNA stage,4QRZZ@28883|Caudovirales,4QMV3@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_96891_1 563192.HMPREF0179_03457 1.61e-30 125.0 COG0749@1|root,COG0749@2|Bacteria,1P27P@1224|Proteobacteria,42YUP@68525|delta/epsilon subdivisions,2WTS1@28221|Deltaproteobacteria,2MAPB@213115|Desulfovibrionales 28221|Deltaproteobacteria L DNA polymerase A domain - - - - - - - - - - - - DNA_pol_A k59_63519_1 157783.LK03_13435 9.24e-60 210.0 COG4733@1|root,COG4733@2|Bacteria,1Q1BS@1224|Proteobacteria,1S3T7@1236|Gammaproteobacteria 1236|Gammaproteobacteria S cellulase activity - - - - - - - - - - - - Phage-tail_3 k59_39065_2 76636.JOEC01000001_gene1138 1.56e-52 186.0 2AYQQ@1|root,31QVM@2|Bacteria,2HT0W@201174|Actinobacteria,4FR6P@85023|Microbacteriaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_223583_2 1692255.A0A0K1RL52_9CIRC 1.64e-73 233.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_39072_2 1609634.A0A0C5AFV4_9VIRU 1.77e-26 108.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_263774_2 1408415.JHXL01000001_gene382 3.98e-08 58.2 COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria 2|Bacteria K chromosome segregation - - 2.1.1.72 ko:K07319 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase,ParBc k59_246098_2 1366055.S5M802_9CAUD 8.18e-13 70.9 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales,4QKM7@10699|Siphoviridae 10699|Siphoviridae S HNH endonuclease - - - - - - - - - - - - - k59_140768_1 1211844.CBLM010000090_gene2700 4.1e-06 55.1 COG2189@1|root,COG2189@2|Bacteria,1UKK3@1239|Firmicutes,3VTXZ@526524|Erysipelotrichia 526524|Erysipelotrichia L DNA methylase - - - - - - - - - - - - N6_N4_Mtase k59_140768_2 1121918.ARWE01000001_gene1957 1.13e-23 95.1 COG1694@1|root,COG1694@2|Bacteria,1N02D@1224|Proteobacteria,42W8Z@68525|delta/epsilon subdivisions,2WS5B@28221|Deltaproteobacteria,43V1B@69541|Desulfuromonadales 28221|Deltaproteobacteria S MazG-like family - - - - - - - - - - - - MazG-like k59_157035_1 105154.Q9MBU6_9VIRU 1.41e-162 476.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_74023_2 869724.H6BI57_9CAUD 7.42e-58 203.0 4QBYN@10239|Viruses,4QZT8@35237|dsDNA viruses no RNA stage,4QR5G@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_164787_1 1415779.JOMH01000001_gene3140 1.05e-17 87.8 COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,1X48C@135614|Xanthomonadales 135614|Xanthomonadales L dna polymerase dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k59_132387_1 195105.CN97_00845 7.32e-37 130.0 29A1W@1|root,2ZX3A@2|Bacteria,1P5QP@1224|Proteobacteria,2UX9U@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_106615_1 1304877.KI519399_gene4996 3.77e-212 686.0 COG0454@1|root,COG0827@1|root,COG1203@1|root,COG0456@2|Bacteria,COG0827@2|Bacteria,COG1203@2|Bacteria,1QZ6D@1224|Proteobacteria,2U5JW@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DNA restriction-modification system - - - - - - - - - - - - AAA_34 k59_190701_1 1732201.A0A0N9N7I3_9CIRC 4.88e-11 68.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_124365_2 521674.Plim_1038 4.28e-27 108.0 2DBWI@1|root,2ZBGQ@2|Bacteria,2J2MN@203682|Planctomycetes 203682|Planctomycetes S Glycosyltransferase family 9 (heptosyltransferase) - - - - - - - - - - - - Glyco_transf_9 k59_197551_3 573.JG24_10890 7.2e-30 109.0 2CH99@1|root,32S5M@2|Bacteria,1N2GH@1224|Proteobacteria,1T0UT@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Recombination enhancement, RecA-dependent nuclease - - - - - - - - - - - - RecA_dep_nuc k59_197551_4 665942.HMPREF1022_00118 9.76e-31 121.0 2C9JF@1|root,32RPD@2|Bacteria,1N8CG@1224|Proteobacteria,42REW@68525|delta/epsilon subdivisions,2WNQ1@28221|Deltaproteobacteria,2MB30@213115|Desulfovibrionales 28221|Deltaproteobacteria S ERF superfamily - - - - - - - - - - - - ERF k59_231419_1 67267.JNXT01000054_gene2989 0.000869 50.8 2F1HE@1|root,33UHX@2|Bacteria,2IH41@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_15065_1 926556.Echvi_2948 4.18e-55 194.0 COG0305@1|root,COG0305@2|Bacteria,4NF8P@976|Bacteroidetes,47JB5@768503|Cytophagia 976|Bacteroidetes L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_23350_1 1453501.JELR01000001_gene2516 2.44e-151 484.0 COG4733@1|root,COG4926@1|root,COG4733@2|Bacteria,COG4926@2|Bacteria,1R77Q@1224|Proteobacteria,1S1WT@1236|Gammaproteobacteria,469QU@72275|Alteromonadaceae 1236|Gammaproteobacteria S Fibronectin type 3 domain - - - - - - - - - - - - - k59_23350_4 1282995.R9W108_9CAUD 4.02e-08 58.9 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_265276_1 1126411.I1TEL3_9CIRC 1.01e-32 130.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_90908_1 1618236.A0A0C5IB23_9CIRC 2.34e-30 124.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_90924_1 1385658.U5KNR1_9VIRU 2.05e-23 102.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_90925_1 743299.Acife_0751 1.69e-06 54.7 COG1896@1|root,COG1896@2|Bacteria,1RACF@1224|Proteobacteria,1S2SY@1236|Gammaproteobacteria 1236|Gammaproteobacteria S 5'-deoxynucleotidase activity yfdR GO:0002953,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050897 - ko:K06952 - - - - ko00000 - - - - k59_90930_1 1383056.S5Y1P0_9CAUD 3.16e-45 174.0 4QM07@10699|Siphoviridae 10699|Siphoviridae S Bacterial DNA polymerase III alpha subunit - - - - - - - - - - - - - k59_90930_7 298654.FraEuI1c_6846 6.08e-29 118.0 COG0270@1|root,COG0270@2|Bacteria,2I8R8@201174|Actinobacteria 201174|Actinobacteria H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_90995_2 1692257.A0A0K1RL39_9CIRC 5.48e-19 86.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_174212_1 2003327.CAPSD_BPCHP 9.63e-23 102.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_190803_1 1618257.A0A0C5IBI9_9CIRC 3.34e-10 66.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_74696_1 348824.LPU83_1717 1.43e-39 144.0 28PTM@1|root,2ZCEU@2|Bacteria,1R5DD@1224|Proteobacteria,2TVG7@28211|Alphaproteobacteria,4BGD7@82115|Rhizobiaceae 28211|Alphaproteobacteria S Family of unknown function (DUF5309) - - - - - - - - - - - - DUF5309 k59_224592_11 742733.HMPREF9469_05076 9.39e-22 95.9 2B7V5@1|root,3211Y@2|Bacteria,1V7MK@1239|Firmicutes,24JA7@186801|Clostridia,222WR@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_224592_12 478749.BRYFOR_08565 2.44e-50 174.0 2A0KC@1|root,2ZGJK@2|Bacteria,1V2JS@1239|Firmicutes,24H6R@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_67058_1 205914.HS_1384 4.34e-42 157.0 28P6A@1|root,2ZC10@2|Bacteria,1RBZE@1224|Proteobacteria,1RRNS@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_770_2 1692244.A0A0K1RLR5_9CIRC 4.7e-12 65.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_150094_1 1385658.U5KPZ6_9VIRU 4.49e-70 230.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_224670_1 1380387.JADM01000008_gene930 3.77e-37 156.0 COG5283@1|root,COG5283@2|Bacteria,1NFKU@1224|Proteobacteria,1RP2D@1236|Gammaproteobacteria,1XKUI@135619|Oceanospirillales 135619|Oceanospirillales S Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_191364_1 1618247.A0A0C5IMK7_9CIRC 0.000687 48.5 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_92069_1 1335760.ASTG01000033_gene40 2e-18 84.3 COG1783@1|root,COG1783@2|Bacteria 2|Bacteria S DNA packaging - - - - - - - - - - - - Terminase_6,Terminase_6C k59_83641_2 232346.JHQL01000009_gene2032 1.96e-58 203.0 2D784@1|root,32TNH@2|Bacteria,1N098@1224|Proteobacteria,1SDM3@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_83641_10 264730.PSPPH_2788 1.91e-74 246.0 COG4128@1|root,COG4128@2|Bacteria,1N0I7@1224|Proteobacteria,1SAH8@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Zonular occludens toxin (Zot) zot GO:0001906,GO:0006810,GO:0006996,GO:0007010,GO:0008150,GO:0009405,GO:0009987,GO:0016043,GO:0031640,GO:0035821,GO:0042044,GO:0042045,GO:0044364,GO:0044419,GO:0051179,GO:0051234,GO:0051704,GO:0070633,GO:0071840 - ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko02042 - - - Zot k59_50550_2 1589297.A0A0B5H2K0_9CAUD 1.95e-56 183.0 4QFIS@10239|Viruses,4QSG1@28883|Caudovirales,4QP3U@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_199770_1 1041930.Mtc_1683 3.64e-14 81.6 COG0614@1|root,COG1520@1|root,COG1572@1|root,arCOG02483@1|root,arCOG02515@1|root,arCOG03557@1|root,arCOG06792@1|root,arCOG02482@2157|Archaea,arCOG02483@2157|Archaea,arCOG02515@2157|Archaea,arCOG02532@2157|Archaea,arCOG03557@2157|Archaea,arCOG03611@2157|Archaea,arCOG06792@2157|Archaea,2XW0A@28890|Euryarchaeota,2NAJX@224756|Methanomicrobia 224756|Methanomicrobia P Protein of unknown function (DUF3344) - - - - - - - - - - - - CARDB,DUF3344,PKD k59_92070_1 488538.SAR116_0383 8.29e-05 49.7 COG4675@1|root,COG4675@2|Bacteria,1Q0KH@1224|Proteobacteria,2UIYI@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Phage Tail Collar Domain - - - - - - - - - - - - Collar k59_249539_3 1234888.K0A2J2_9VIRU 4.78e-158 464.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_141857_1 1217718.ALOU01000040_gene127 1.82e-08 55.1 COG1089@1|root,COG1089@2|Bacteria,1MUX0@1224|Proteobacteria,2VIBX@28216|Betaproteobacteria,1K0D3@119060|Burkholderiaceae 28216|Betaproteobacteria M Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose gmd - 4.2.1.47 ko:K01711 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R00888 RC00402 ko00000,ko00001,ko01000 - - - GDP_Man_Dehyd k59_166658_6 1379712.S5TMV9_9CIRC 9e-17 89.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_233504_2 497964.CfE428DRAFT_0770 1.66e-19 84.7 2DSBU@1|root,33FEQ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_158881_1 1562701.BBOF01000081_gene253 1.19e-73 237.0 28NGF@1|root,2Z9HT@2|Bacteria,1R9QF@1224|Proteobacteria,2VPSU@28216|Betaproteobacteria,1KD23@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_92802_1 1234888.K0A2R8_9VIRU 3.36e-52 177.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_92802_5 1234888.K0A2J2_9VIRU 1.6e-127 383.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_217683_1 428125.CLOLEP_03592 0.000569 49.3 COG0673@1|root,COG0673@2|Bacteria,1TPT5@1239|Firmicutes,248MV@186801|Clostridia,3WI38@541000|Ruminococcaceae 186801|Clostridia S domain protein - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C k59_217683_2 1380394.JADL01000007_gene4590 1.13e-22 98.2 COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2TRIQ@28211|Alphaproteobacteria,2JQ62@204441|Rhodospirillales 204441|Rhodospirillales E Belongs to the DegT DnrJ EryC1 family - - 2.6.1.87 ko:K07806 ko00520,ko01503,ko02020,map00520,map01503,map02020 M00721,M00761 R07659 RC00006,RC01514 ko00000,ko00001,ko00002,ko01000,ko01005,ko01007 - - - DegT_DnrJ_EryC1 k59_76405_1 316067.Geob_0661 1.65e-09 58.5 COG2518@1|root,COG2518@2|Bacteria,1PZID@1224|Proteobacteria,431NU@68525|delta/epsilon subdivisions 1224|Proteobacteria O Methyltransferase domain - - - - - - - - - - - - Methyltransf_25 k59_76405_2 1131812.JQMS01000001_gene285 6.01e-38 142.0 COG0028@1|root,COG0028@2|Bacteria,4NENG@976|Bacteroidetes,1HXF9@117743|Flavobacteriia,2NU34@237|Flavobacterium 976|Bacteroidetes E acetolactate synthase large subunit - - - - - - - - - - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k59_126260_1 1121937.AUHJ01000007_gene1928 4.18e-26 100.0 2CJKM@1|root,314EI@2|Bacteria,1N8C9@1224|Proteobacteria,1SGI2@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_126260_2 69328.PVLB_09055 2.63e-25 97.8 2D7I9@1|root,32TP3@2|Bacteria,1N2ZM@1224|Proteobacteria,1S9DB@1236|Gammaproteobacteria 1236|Gammaproteobacteria S phage protein ybcO - - - - - - - - - - - DUF1364 k59_183949_2 1411685.U062_00592 8.17e-76 244.0 2EW57@1|root,33PIB@2|Bacteria,1NQQA@1224|Proteobacteria,1SMVX@1236|Gammaproteobacteria,1J7VZ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Phage replication protein CRI - - - - - - - - - - - - Phage_CRI k59_43253_4 37554.Q9MCR7_BPHK7 1.49e-09 62.4 4QAQ9@10239|Viruses,4QUYQ@35237|dsDNA viruses no RNA stage,4QPTV@28883|Caudovirales,4QKRS@10699|Siphoviridae 10699|Siphoviridae S Putative phage tail protein - GO:0005575,GO:0008150,GO:0016032,GO:0018995,GO:0019012,GO:0019058,GO:0019062,GO:0022610,GO:0030430,GO:0033643,GO:0033646,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044403,GO:0044406,GO:0044419,GO:0044650,GO:0051704 - - - - - - - - - - - k59_200556_1 935948.KE386495_gene1203 7.64e-67 228.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,42HQD@68295|Thermoanaerobacterales 186801|Clostridia KL SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,SNF2_N k59_2030_1 216595.PFLU_2867 5.71e-18 84.3 COG4626@1|root,COG4626@2|Bacteria,1R2FH@1224|Proteobacteria,1RN1F@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Terminase - - - - - - - - - - - - - k59_134563_2 665942.HMPREF1022_03278 3.89e-26 110.0 28MSK@1|root,2ZB0X@2|Bacteria,1R7CY@1224|Proteobacteria,42YXC@68525|delta/epsilon subdivisions,2WTJ0@28221|Deltaproteobacteria,2M9DF@213115|Desulfovibrionales 28221|Deltaproteobacteria S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_92907_1 398767.Glov_1841 1.12e-14 71.6 COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,42SJS@68525|delta/epsilon subdivisions,2WP7N@28221|Deltaproteobacteria 28221|Deltaproteobacteria F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA dut - 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase k59_225807_2 1110502.TMO_0040 3.13e-13 69.7 COG3926@1|root,COG3926@2|Bacteria,1MVXW@1224|Proteobacteria,2TT3H@28211|Alphaproteobacteria,2JUIF@204441|Rhodospirillales 204441|Rhodospirillales S Glycosyl hydrolase 108 - - - - - - - - - - - - Glyco_hydro_108,PG_binding_3 k59_250351_2 865937.Gilli_1112 2.31e-39 149.0 29ZGV@1|root,30MGK@2|Bacteria,4PA9P@976|Bacteroidetes,1IMU2@117743|Flavobacteriia,2P7HK@244698|Gillisia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_192116_1 349161.Dred_1192 6.74e-55 189.0 COG0553@1|root,COG0553@2|Bacteria,1TP2C@1239|Firmicutes,24DVA@186801|Clostridia 186801|Clostridia L DEAD-like helicases superfamily - - - - - - - - - - - - Helicase_C,N6_N4_Mtase,SNF2_N k59_192116_2 1089548.KI783301_gene2629 3.45e-17 80.5 COG0863@1|root,COG0863@2|Bacteria,1UZIN@1239|Firmicutes,4HU16@91061|Bacilli 91061|Bacilli L DNA methylase - - - - - - - - - - - - N6_N4_Mtase k59_184030_2 105154.Q9MBU6_9VIRU 1.21e-60 202.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_43347_1 135651.CBN29975 2.62e-14 82.0 COG5108@1|root,KOG1038@2759|Eukaryota,38EAY@33154|Opisthokonta,3B9IU@33208|Metazoa,3CT0T@33213|Bilateria,40C2G@6231|Nematoda,1KU92@119089|Chromadorea,4102G@6236|Rhabditida 33208|Metazoa KL DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates POLRMT GO:0000428,GO:0000959,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006139,GO:0006351,GO:0006352,GO:0006390,GO:0006391,GO:0006725,GO:0006807,GO:0006996,GO:0007005,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0031974,GO:0032774,GO:0032991,GO:0034062,GO:0034245,GO:0034641,GO:0034645,GO:0034654,GO:0042645,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0061695,GO:0070013,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097659,GO:0097747,GO:0098798,GO:0140053,GO:0140098,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990234 2.7.11.1,2.7.7.6 ko:K10908,ko:K16310 - - - - ko00000,ko01000,ko01001,ko03029 - - - RNA_pol,RPOL_N k59_250511_48 1410653.JHVC01000023_gene1221 5.92e-05 51.6 COG2188@1|root,COG2188@2|Bacteria,1VG2E@1239|Firmicutes,25EDC@186801|Clostridia,36UM0@31979|Clostridiaceae 186801|Clostridia K PFAM Firmicute plasmid replication protein (RepL) - - - - - - - - - - - - HTH_36 k59_250511_54 1088869.GMO_17650 1.65e-47 159.0 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,2U5BZ@28211|Alphaproteobacteria,2JRQZ@204441|Rhodospirillales 204441|Rhodospirillales L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_118649_1 1618247.A0A0C5IMK7_9CIRC 5.09e-08 60.1 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_109890_2 640513.Entas_4197 9.1e-05 48.5 COG1670@1|root,COG1670@2|Bacteria,1RC7M@1224|Proteobacteria,1S20T@1236|Gammaproteobacteria,3X2AE@547|Enterobacter 1236|Gammaproteobacteria J Acetyltransferase (GNAT) domain ydaF_2 - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 k59_118650_2 665956.HMPREF1032_00674 3.38e-48 168.0 28J3N@1|root,2Z8ZU@2|Bacteria,1V15Z@1239|Firmicutes,249Z0@186801|Clostridia,3WNJZ@541000|Ruminococcaceae 186801|Clostridia S Phage portal protein - - - - - - - - - - - - Phage_portal k59_218202_1 1122194.AUHU01000013_gene665 8.27e-105 320.0 COG4128@1|root,COG4128@2|Bacteria,1REHG@1224|Proteobacteria,1S491@1236|Gammaproteobacteria,46BRE@72275|Alteromonadaceae 1236|Gammaproteobacteria S Zonular occludens toxin (Zot) - - - - - - - - - - - - Zot k59_84650_2 1618240.A0A0C5IMJ1_9CIRC 3.77e-10 62.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_168296_4 1165094.RINTHH_3920 8.17e-77 244.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_168296_6 1385658.U5KPZ6_9VIRU 7.3e-199 571.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_250599_1 323261.Noc_1974 2.66e-13 80.5 COG0823@1|root,COG0823@2|Bacteria,1R4CN@1224|Proteobacteria,1S0NH@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Involved in the tonB-independent uptake of proteins - - - - - - - - - - - - PD40 k59_126884_1 1414720.CBYM010000040_gene1655 1.73e-14 79.0 COG5283@1|root,COG5412@1|root,COG5283@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,247QT@186801|Clostridia,36E7F@31979|Clostridiaceae 186801|Clostridia M tail tape measure protein - - - - - - - - - - - - PhageMin_Tail k59_192505_1 1385658.U5KNR1_9VIRU 6.29e-37 139.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_151728_2 1123020.AUIE01000007_gene3229 7.22e-54 177.0 2CJWY@1|root,31CWF@2|Bacteria,1RKEF@1224|Proteobacteria,1S75P@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_151728_3 1123020.AUIE01000007_gene3230 5.32e-43 143.0 COG5614@1|root,COG5614@2|Bacteria,1N9Y5@1224|Proteobacteria,1SHES@1236|Gammaproteobacteria 1236|Gammaproteobacteria S head-tail adaptor - - - - - - - - - - - - Phage_H_T_join k59_84657_1 1123279.ATUS01000005_gene3101 2.86e-28 117.0 COG4653@1|root,COG4653@2|Bacteria,1MYMH@1224|Proteobacteria,1RR5E@1236|Gammaproteobacteria 1236|Gammaproteobacteria S capsid protein - - - - - - - - - - - - Phage_capsid k59_185516_4 698757.Pogu_0468 5.53e-08 60.5 COG0209@1|root,COG1372@1|root,arCOG03151@2157|Archaea,arCOG04276@2157|Archaea,2XQ2F@28889|Crenarchaeota 28889|Crenarchaeota F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrd - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,Intein_splicing,LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN k59_69462_5 1417599.U6C697_9CAUD 2.92e-42 164.0 4QBFN@10239|Viruses,4QXWN@35237|dsDNA viruses no RNA stage,4QPTW@28883|Caudovirales,4QNPZ@10744|Podoviridae 10744|Podoviridae S Phage stabilisation protein - - - - - - - - - - - - - k59_177236_1 91464.S7335_4791 5.3e-93 287.0 COG0451@1|root,COG0451@2|Bacteria,1G0TM@1117|Cyanobacteria,1GZ9Q@1129|Synechococcus 1117|Cyanobacteria GM Sulfolipid (UDP-sulfoquinovose) biosynthesis protein sqdB - 3.13.1.1 ko:K06118 ko00520,ko00561,map00520,map00561 - R05775 RC01469 ko00000,ko00001,ko01000 - - iJN678.sqdB Epimerase k59_243415_2 1379722.S5SY31_9CIRC 7.24e-25 100.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_185522_2 272134.KB731324_gene2860 4.35e-36 130.0 COG1351@1|root,COG1351@2|Bacteria,1G3FM@1117|Cyanobacteria,1HEHP@1150|Oscillatoriales 1117|Cyanobacteria F Thymidylate synthase complementing protein thyX - 2.1.1.148 ko:K03465 ko00240,ko00670,ko01100,map00240,map00670,map01100 - R06613 RC00022,RC00332 ko00000,ko00001,ko01000 - - - Thy1 k59_94059_1 1264700.L0MYI2_9CAUD 2.12e-90 285.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QI9F@10662|Myoviridae 10662|Myoviridae S Type III restriction enzyme, res subunit - - - - - - - - - - - - - k59_160512_1 1046714.AMRX01000006_gene3191 1.51e-53 180.0 28JC4@1|root,2Z96S@2|Bacteria,1RI8W@1224|Proteobacteria,1S6FI@1236|Gammaproteobacteria 1236|Gammaproteobacteria S P22 coat protein-protein 5 domain protein - - - - - - - - - - - - - k59_169422_1 1165094.RINTHH_3920 9.89e-52 177.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_169422_3 1385658.U5KPZ6_9VIRU 8.39e-83 263.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_60783_1 935261.JAGL01000009_gene1160 2.37e-17 87.8 2DUXE@1|root,32UY2@2|Bacteria,1N2YI@1224|Proteobacteria,2UEWK@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Phage T7 capsid assembly protein - - - - - - - - - - - - Phage_T7_Capsid k59_69660_1 1158150.KB906242_gene227 2.26e-69 233.0 28IA2@1|root,2Z8CQ@2|Bacteria,1PQM2@1224|Proteobacteria,1SN3W@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_251576_2 1219035.NT2_13_00580 6.11e-57 201.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_235737_2 1408418.JNJH01000002_gene2754 4.46e-14 79.3 COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,2TT4Q@28211|Alphaproteobacteria,2JV16@204441|Rhodospirillales 204441|Rhodospirillales L Uracil DNA glycosylase superfamily - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k59_170704_2 1288494.EBAPG3_15130 1.25e-49 178.0 COG4383@1|root,COG4383@2|Bacteria,1MWNS@1224|Proteobacteria,2VJIH@28216|Betaproteobacteria 28216|Betaproteobacteria S Protein of unknown function (DUF935) - - - - - - - - - - - - DUF935 k59_86393_1 1423724.BAMM01000004_gene688 1.16e-08 55.5 COG1694@1|root,COG1694@2|Bacteria,1VIQA@1239|Firmicutes,4HM6C@91061|Bacilli,3F6WJ@33958|Lactobacillaceae 91061|Bacilli S mazG nucleotide pyrophosphohydrolase - - - - - - - - - - - - MazG k59_146157_2 205914.HS_1385 9.29e-47 176.0 COG1783@1|root,COG1783@2|Bacteria,1RAGC@1224|Proteobacteria 1224|Proteobacteria S phage Terminase large subunit - - - - - - - - - - - - - k59_146157_3 1325372.N0DPG8_9CAUD 9.73e-13 71.2 4QBHW@10239|Viruses,4QW8N@35237|dsDNA viruses no RNA stage,4QTT7@28883|Caudovirales,4QJZQ@10662|Myoviridae 10662|Myoviridae S sequence-specific DNA binding transcription factor activity - - - - - - - - - - - - - k59_146157_5 1280001.BAOA01000081_gene3007 1.17e-21 88.2 2EVSB@1|root,33P68@2|Bacteria,1P3SK@1224|Proteobacteria,1SS80@1236|Gammaproteobacteria,1XYJ3@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF1353) - - - - - - - - - - - - DUF1353 k59_170918_2 216595.PFLU_4014 4.87e-23 90.5 2EFPQ@1|root,339FQ@2|Bacteria,1NA0K@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_170918_4 1168034.FH5T_14940 4.85e-17 78.2 COG1525@1|root,COG1525@2|Bacteria,4NR4U@976|Bacteroidetes 976|Bacteroidetes L Staphylococcal nuclease homologue - - 3.1.31.1 ko:K01174 - - - - ko00000,ko01000 - - - SNase k59_235893_1 398512.JQKC01000009_gene437 5.37e-28 114.0 COG3378@1|root,COG4983@1|root,COG3378@2|Bacteria,COG4983@2|Bacteria,1TQP9@1239|Firmicutes,24AY6@186801|Clostridia,3WHX7@541000|Ruminococcaceae 186801|Clostridia S Phage plasmid primase, P4 family - - - ko:K06919 - - - - ko00000 - - - D5_N,Pox_D5,PriCT_1,Prim-Pol k59_221352_1 488538.SAR116_0387 5.23e-27 110.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2TS19@28211|Alphaproteobacteria,4BP86@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides - - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_lgC,Ribonuc_red_lgN k59_221352_3 438753.AZC_3597 3.68e-19 88.2 COG0749@1|root,COG0749@2|Bacteria,1P27P@1224|Proteobacteria,2TVEI@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DNA polymerase family A - - - - - - - - - - - - DNA_pol_A k59_187060_2 547045.NEISICOT_01400 3.81e-25 104.0 COG4653@1|root,COG4653@2|Bacteria,1MWMB@1224|Proteobacteria,2VN8K@28216|Betaproteobacteria 28216|Betaproteobacteria S Phage capsid family - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_252702_2 1395983.A0A067Y168_9CAUD 3.35e-85 270.0 4QB3X@10239|Viruses,4QWKP@35237|dsDNA viruses no RNA stage,4QPEE@28883|Caudovirales,4QNCI@10744|Podoviridae 10744|Podoviridae S VWA-like domain (DUF2201) - - - - - - - - - - - - - k59_70866_1 1141663.OOC_13824 5.02e-06 53.1 COG4974@1|root,COG4974@2|Bacteria,1QUDX@1224|Proteobacteria,1T1VB@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Belongs to the 'phage' integrase family intE - - - - - - - - - - - Arm-DNA-bind_1,Phage_int_SAM_1,Phage_integrase k59_29884_1 78345.BMERY_0715 2.53e-07 57.4 COG0011@1|root,COG0011@2|Bacteria,2H6VK@201174|Actinobacteria,4D1T9@85004|Bifidobacteriales 201174|Actinobacteria S Thiamine-binding protein - - - - - - - - - - - - Thiamine_BP k59_211175_1 460265.Mnod_1996 1.33e-11 68.9 COG4695@1|root,COG4695@2|Bacteria,1MUP5@1224|Proteobacteria,2U0DJ@28211|Alphaproteobacteria,1JVTV@119045|Methylobacteriaceae 28211|Alphaproteobacteria S Phage portal protein - - - - - - - - - - - - Phage_portal k59_105170_1 2003327.CAPSD_BPCHP 3.34e-15 82.4 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_47954_1 349965.yinte0001_8640 3.74e-49 169.0 COG4249@1|root,COG4249@2|Bacteria,1QPXG@1224|Proteobacteria,1S1R1@1236|Gammaproteobacteria,41GXS@629|Yersinia 1236|Gammaproteobacteria S Caspase domain - - - - - - - - - - - - Peptidase_C14 k59_47954_2 40373.F991_00517 3.26e-36 124.0 2FB2D@1|root,34392@2|Bacteria,1N749@1224|Proteobacteria,1SSCS@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_47954_3 40373.F991_00515 1.25e-64 199.0 2C8CT@1|root,32WE6@2|Bacteria,1RHFE@1224|Proteobacteria,1SJDD@1236|Gammaproteobacteria 1236|Gammaproteobacteria S TIR domain - - - - - - - - - - - - TIR_2 k59_179968_1 1380355.JNIJ01000008_gene1952 8.26e-20 91.7 COG2369@1|root,COG2369@2|Bacteria,1P87U@1224|Proteobacteria,2TSNA@28211|Alphaproteobacteria 28211|Alphaproteobacteria S head morphogenesis protein, SPP1 - - - - - - - - - - - - Phage_Mu_F k59_229787_1 1211844.CBLM010000090_gene2699 1.24e-12 71.2 COG0338@1|root,COG0338@2|Bacteria,1TRDX@1239|Firmicutes 1239|Firmicutes L site-specific DNA-methyltransferase (Adenine-specific) dam - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 k59_229787_2 1121024.AUCD01000023_gene726 1.11e-13 77.8 COG2189@1|root,COG2189@2|Bacteria,1UHUQ@1239|Firmicutes,4HCEV@91061|Bacilli 91061|Bacilli L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_188700_8 991.IW20_15610 1.01e-20 89.7 2FJ8D@1|root,34AYE@2|Bacteria,4P5J9@976|Bacteroidetes,1IAP3@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_212320_3 1120966.AUBU01000031_gene2980 2.99e-09 62.8 COG5384@1|root,COG5384@2|Bacteria 2|Bacteria J extracellular matrix structural constituent - - - - - - - - - - - - DUF4347,F5_F8_type_C k59_72339_1 691966.D4P709_9CAUD 2.37e-38 144.0 4QGMJ@10239|Viruses,4QX02@35237|dsDNA viruses no RNA stage,4QSYG@28883|Caudovirales,4QM5B@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_195883_2 1121935.AQXX01000130_gene2449 5.63e-119 350.0 COG3723@1|root,COG3723@2|Bacteria,1R6DB@1224|Proteobacteria,1RZZ3@1236|Gammaproteobacteria 1236|Gammaproteobacteria L COG3723 Recombinational DNA repair protein (RecE pathway) recT GO:0000724,GO:0000725,GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0018130,GO:0019438,GO:0032392,GO:0032508,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043150,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071704,GO:0071840,GO:0071897,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - ko:K07455 - - - - ko00000,ko03400 - - - RecT k59_21657_1 1609634.A0A0C5AFV4_9VIRU 1.22e-61 206.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_55955_1 1124982.MSI_22820 1.37e-18 89.4 COG1502@1|root,COG1502@2|Bacteria,2J6X1@203691|Spirochaetes 203691|Spirochaetes I ORF6N domain - - - - - - - - - - - - ORF6N k59_114532_2 348824.LPU83_1721 7.01e-26 110.0 COG0507@1|root,COG0507@2|Bacteria,1R1AT@1224|Proteobacteria,2U1ZX@28211|Alphaproteobacteria,4BAYZ@82115|Rhizobiaceae 28211|Alphaproteobacteria L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD - - - - - - - - - - - - Terminase_6 k59_188855_1 596323.HMPREF0554_0847 2.39e-18 81.6 2FCPU@1|root,344T2@2|Bacteria,37CG7@32066|Fusobacteria 32066|Fusobacteria - - - - - - - - - - - - - - - k59_188855_2 497964.CfE428DRAFT_4747 1.72e-07 55.5 COG1974@1|root,COG1974@2|Bacteria,46SU8@74201|Verrucomicrobia 74201|Verrucomicrobia K Represses a number of genes involved in the response to DNA damage (SOS response) - - 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 k59_172395_2 1609634.A0A0C5AFV4_9VIRU 4.2e-245 689.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_206209_1 1132026.I6NMA5_9CAUD 1.4e-30 127.0 4QAQ9@10239|Viruses,4QUYQ@35237|dsDNA viruses no RNA stage,4QPTV@28883|Caudovirales,4QKRS@10699|Siphoviridae 10699|Siphoviridae S Putative phage tail protein - GO:0005575,GO:0008150,GO:0016032,GO:0018995,GO:0019012,GO:0019058,GO:0019062,GO:0022610,GO:0030430,GO:0033643,GO:0033646,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044403,GO:0044406,GO:0044419,GO:0044650,GO:0051704 - - - - - - - - - - - k59_173418_1 1335760.ASTG01000033_gene19 2.22e-47 160.0 COG4712@1|root,COG4712@2|Bacteria,1N9U1@1224|Proteobacteria,2UVCK@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Rad52/22 family double-strand break repair protein - - - - - - - - - - - - Rad52_Rad22 k59_196723_1 1249997.JHZW01000002_gene40 1.33e-97 320.0 COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,4NG54@976|Bacteroidetes,1I01C@117743|Flavobacteriia 976|Bacteroidetes L Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_97100_5 375286.mma_2192 0.000275 52.4 2ES6Y@1|root,33JRQ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_97100_6 1121438.JNJA01000039_gene1897 1.9e-05 57.0 2DNH7@1|root,32XH1@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_131688_1 1692244.A0A0K1RLR5_9CIRC 1.88e-46 162.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_115476_2 742727.HMPREF9447_01719 7.25e-40 149.0 COG1032@1|root,COG1032@2|Bacteria,4NZ46@976|Bacteroidetes,2FNXU@200643|Bacteroidia,4APA0@815|Bacteroidaceae 976|Bacteroidetes C radical SAM domain protein - - - - - - - - - - - - - k59_131770_1 438753.AZC_3589 3.46e-189 550.0 COG0209@1|root,COG0209@2|Bacteria,1N0E3@1224|Proteobacteria,2UQM4@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Ribonucleotide reductase, barrel domain - - 1.1.98.6 ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000 - - - Ribonuc_red_lgC k59_206299_1 1158150.KB906242_gene227 9.06e-78 258.0 28IA2@1|root,2Z8CQ@2|Bacteria,1PQM2@1224|Proteobacteria,1SN3W@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_190111_1 444878.E3SQY6_9CAUD 0.000614 49.3 4QFPG@10239|Viruses,4QWZI@35237|dsDNA viruses no RNA stage,4QS3K@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_22723_2 314264.ROS217_00950 0.00067 43.5 COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,2TTXT@28211|Alphaproteobacteria,46RG2@74030|Roseovarius 28211|Alphaproteobacteria L Phage integrase family - - - - - - - - - - - - Phage_int_SAM_4,Phage_integrase k59_49257_1 1123269.NX02_21910 1.19e-05 49.3 299N2@1|root,2ZWQE@2|Bacteria,1NK8N@1224|Proteobacteria,2V0UA@28211|Alphaproteobacteria,2K82Y@204457|Sphingomonadales 204457|Sphingomonadales S Bacteriophage HK97-gp10, putative tail-component - - - - - - - - - - - - HK97-gp10_like k59_88228_1 1345023.M467_06655 3.45e-10 62.8 COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,4HBHA@91061|Bacilli,3WEPN@539002|Bacillales incertae sedis 91061|Bacilli K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair lexA GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 k59_255948_4 573174.M4MHT9_9VIRU 3.86e-11 66.6 4QAQ9@10239|Viruses,4QUYQ@35237|dsDNA viruses no RNA stage 10239|Viruses - - - GO:0005575,GO:0008150,GO:0016032,GO:0018995,GO:0019012,GO:0019058,GO:0019062,GO:0022610,GO:0030430,GO:0033643,GO:0033646,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044403,GO:0044406,GO:0044419,GO:0044650,GO:0051704 - - - - - - - - - - - k59_57919_1 1157943.KB892705_gene2039 2.71e-55 187.0 COG3969@1|root,COG3969@2|Bacteria,2H4MT@201174|Actinobacteria 201174|Actinobacteria S Phosphoadenosine phosphosulfate reductase family - - - - - - - - - - - - PAPS_reduct k59_15546_1 886379.AEWI01000001_gene1751 3.74e-14 71.2 COG2852@1|root,COG2852@2|Bacteria,4NX7B@976|Bacteroidetes,2FV38@200643|Bacteroidia 976|Bacteroidetes S Protein conserved in bacteria - - - - - - - - - - - - - k59_15546_3 1286093.C266_19128 3.15e-27 102.0 2CH99@1|root,32S5M@2|Bacteria,1N2GH@1224|Proteobacteria,2W6BX@28216|Betaproteobacteria,1KB4Z@119060|Burkholderiaceae 28216|Betaproteobacteria S Recombination enhancement, RecA-dependent nuclease - - - - - - - - - - - - RecA_dep_nuc k59_15546_4 1168281.I3PV01_9CAUD 1.15e-56 184.0 4QDSU@10239|Viruses,4QUZQ@35237|dsDNA viruses no RNA stage,4QQ23@28883|Caudovirales 28883|Caudovirales S Protein of unknown function (DUF1367) - - - - - - - - - - - - - k59_57927_1 388051.AUFE01000035_gene4020 3.02e-47 167.0 COG4653@1|root,COG4653@2|Bacteria 2|Bacteria G Phage capsid family - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_264917_2 1618236.A0A0C5IB23_9CIRC 4.5e-45 163.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_82288_2 1788444.A0A190WHB9_9CIRC 8.89e-35 134.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_23955_1 1379708.S5SYC3_9CIRC 3e-38 140.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_88973_1 4897.EEB07890 1.01e-28 120.0 COG5108@1|root,KOG1038@2759|Eukaryota,38EAY@33154|Opisthokonta,3NU1C@4751|Fungi,3QN4S@4890|Ascomycota,3MC4J@451866|Taphrinomycotina 4751|Fungi KL DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates RPO41 GO:0000002,GO:0000428,GO:0000959,GO:0001018,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006351,GO:0006390,GO:0006725,GO:0006807,GO:0006996,GO:0007005,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0031974,GO:0032774,GO:0032991,GO:0034062,GO:0034245,GO:0034641,GO:0034645,GO:0034654,GO:0042645,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0061695,GO:0070013,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097659,GO:0097747,GO:0098798,GO:0140053,GO:0140098,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K10908 - - - - ko00000,ko01000,ko03029 - - - RNA_pol,RPOL_N k59_207243_1 1385658.U5KNR1_9VIRU 1.86e-23 100.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_23956_2 1788454.A0A190WHE4_9CIRC 7.14e-47 165.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_182002_3 760192.Halhy_0214 5.15e-05 53.9 COG3291@1|root,COG3386@1|root,COG3291@2|Bacteria,COG3386@2|Bacteria,4PN79@976|Bacteroidetes 976|Bacteroidetes G C-terminal domain of CHU protein family - - - - - - - - - - - - CHU_C k59_239119_5 1986029.Q9MBM3_9VIRU 5.95e-23 99.4 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_107008_1 1502724.FF80_03116 1.47e-12 67.4 COG0175@1|root,COG0175@2|Bacteria,1QZJ1@1224|Proteobacteria,2U233@28211|Alphaproteobacteria 28211|Alphaproteobacteria EH sulfate reduction - - - - - - - - - - - - - k59_232516_1 1244869.H261_11074 3.98e-07 60.1 COG4733@1|root,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria,2TV2W@28211|Alphaproteobacteria,2JV2T@204441|Rhodospirillales 204441|Rhodospirillales S COG4733 Phage-related protein, tail component - - - - - - - - - - - - Lambda_tail_I,Phage-tail_3 k59_207574_2 145579.REP_BPPHM 2.83e-18 90.5 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_33497_1 1121940.AUDZ01000007_gene2181 1.48e-34 134.0 2EC16@1|root,3360E@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DUF4373,HTH_36 k59_58312_1 1692250.A0A0K1RLR1_9CIRC 2.2e-41 144.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_58312_3 1692255.A0A0K1RL52_9CIRC 1.27e-48 169.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_224094_4 1416009.V9VG10_9CAUD 2.9e-12 67.4 4QAR6@10239|Viruses,4QUTK@35237|dsDNA viruses no RNA stage,4QPS2@28883|Caudovirales,4QNRU@10744|Podoviridae 10744|Podoviridae S dUTPase - - - - - - - - - - - - - k59_33567_1 1217710.F969_00036 2.43e-30 123.0 COG5565@1|root,COG5565@2|Bacteria,1R6R3@1224|Proteobacteria,1RY0J@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C k59_354_1 1788439.A0A190WHD0_9CIRC 5.49e-27 111.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_232568_1 160488.PP_2269 3.64e-25 100.0 COG3023@1|root,COG3023@2|Bacteria,1N032@1224|Proteobacteria,1SA9C@1236|Gammaproteobacteria 1236|Gammaproteobacteria V N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - Amidase_2 k59_232568_2 1220601.L7TJ68_9CAUD 3.52e-35 124.0 4QASP@10239|Viruses,4QVR8@35237|dsDNA viruses no RNA stage,4QR4Z@28883|Caudovirales 28883|Caudovirales S deoxyribonuclease IV (phage-T4-induced) activity - - - - - - - - - - - - - k59_75008_3 870187.Thini_0411 5.23e-22 100.0 2EP1Y@1|root,33GNT@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_208063_3 1165094.RINTHH_3920 1.02e-41 154.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_208063_7 1609634.A0A0C5AFV4_9VIRU 1.71e-74 242.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_158364_1 573061.Clocel_3533 2.1e-20 95.9 COG5280@1|root,COG5412@1|root,COG5280@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,247QT@186801|Clostridia,36E7F@31979|Clostridiaceae 186801|Clostridia M tail tape measure protein - - - - - - - - - - - - PhageMin_Tail k59_125479_2 77856.REP_BFDV 2.29e-19 90.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_50737_3 1379692.S5SXY7_9CIRC 2.01e-26 110.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_216898_1 105154.Q9MBU6_9VIRU 1.25e-37 144.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_108843_1 1385658.U5KPZ6_9VIRU 1.05e-60 204.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_117166_2 485913.Krac_6819 1.06e-06 52.4 293RF@1|root,2ZR72@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_174917_2 457421.CBFG_05519 0.000122 51.6 COG2946@1|root,COG2946@2|Bacteria,1UHNT@1239|Firmicutes,24ZUP@186801|Clostridia,26C0F@186813|unclassified Clostridiales 186801|Clostridia L Replication initiation factor - - - ko:K07467 - - - - ko00000 - - - HTH_3,Rep_trans k59_83872_1 1328313.DS2_19166 3.67e-21 92.8 2CI0W@1|root,2Z81W@2|Bacteria,1R9FZ@1224|Proteobacteria,1S0NA@1236|Gammaproteobacteria,46B4Q@72275|Alteromonadaceae 1236|Gammaproteobacteria S Phage X family - - - - - - - - - - - - Phage_CRI,Phage_X k59_9299_3 1207063.P24_13825 3.65e-58 201.0 2DIIY@1|root,303ET@2|Bacteria,1RD2S@1224|Proteobacteria,2U8HK@28211|Alphaproteobacteria,2JX0C@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - k59_9299_9 322855.Q52PM1_9CAUD 9.77e-65 214.0 4QAK6@10239|Viruses,4QPBY@28883|Caudovirales 28883|Caudovirales S N-acetylmuramoyl-L-alanine amidase activity - - - - - - - - - - - - - k59_9299_10 1304872.JAGC01000009_gene762 7.7e-39 142.0 28IY5@1|root,2Z8VY@2|Bacteria,1RC9Z@1224|Proteobacteria,430E9@68525|delta/epsilon subdivisions,2WW2H@28221|Deltaproteobacteria,2MF3D@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_9299_14 1548905.A0A0A1IX09_9CAUD 4.81e-12 77.0 4QC5Z@10239|Viruses,4QPGX@28883|Caudovirales,4QKMB@10699|Siphoviridae 10699|Siphoviridae S Phage Mu protein F like protein - GO:0005575,GO:0019012,GO:0019028,GO:0044423,GO:0046729 - - - - - - - - - - - k59_9299_15 1218352.B597_019385 4.16e-72 242.0 28IAN@1|root,2Z8D8@2|Bacteria,1NJD6@1224|Proteobacteria,1RY86@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4055) - - - - - - - - - - - - DUF4055 k59_9299_16 351746.Pput_3380 3.06e-149 437.0 COG1783@1|root,COG1783@2|Bacteria,1MWGP@1224|Proteobacteria,1RMTH@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_142160_1 1618247.A0A0C5IMK7_9CIRC 1.09e-07 59.3 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_1291_1 1234888.K0A2J2_9VIRU 4.32e-130 393.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_200659_3 1498011.A0A096XUV3_9CAUD 1.61e-92 278.0 4QAUS@10239|Viruses,4QQ2S@28883|Caudovirales 28883|Caudovirales S flavin adenine dinucleotide binding - - - - - - - - - - - - - k59_200659_4 1498011.A0A096XUY1_9CAUD 2.28e-25 103.0 4QHBE@10239|Viruses,4QT2W@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_84453_2 1165094.RINTHH_3920 5.19e-52 181.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_26891_1 1498011.A0A096XUT1_9CAUD 1.53e-25 100.0 4QC50@10239|Viruses,4QS0Z@28883|Caudovirales,4QNPK@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_225816_1 314278.NB231_05901 1.72e-57 191.0 COG5549@1|root,COG5549@2|Bacteria,1R9BR@1224|Proteobacteria,1S1JP@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Zinc-dependent metalloprotease - - - - - - - - - - - - Astacin,Peptidase_M10 k59_142924_11 398525.KB900701_gene5078 3.4e-27 129.0 COG4733@1|root,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria,2TV2W@28211|Alphaproteobacteria,3JW1G@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S COG4733 Phage-related protein, tail component - - - - - - - - - - - - Phage-tail_3 k59_142924_15 1122214.AQWH01000025_gene4965 0.000254 50.8 COG5281@1|root,COG5281@2|Bacteria,1R47M@1224|Proteobacteria,2TUIV@28211|Alphaproteobacteria,2PJW4@255475|Aurantimonadaceae 28211|Alphaproteobacteria S COG5281, Phage-related minor tail protein - - - - - - - - - - - - - k59_2047_2 1316936.K678_04874 2.09e-16 73.9 2E5X1@1|root,330KZ@2|Bacteria,1N8Z4@1224|Proteobacteria,2UF7M@28211|Alphaproteobacteria,2JU50@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - k59_225818_1 1234888.K0A2J2_9VIRU 1.56e-20 95.1 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_250359_1 1112209.AHVZ01000022_gene1141 2.99e-133 380.0 COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,1S23A@1236|Gammaproteobacteria,3NJ0U@468|Moraxellaceae 1236|Gammaproteobacteria JM COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) - GO:0000166,GO:0000270,GO:0000287,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0005488,GO:0006022,GO:0006040,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019752,GO:0030203,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044281,GO:0046872,GO:0070569,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.7.13,2.7.7.99 ko:K00966,ko:K00992 ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110 M00114,M00361,M00362 R00885,R11025 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase k59_126347_1 105154.Q9MBU6_9VIRU 3.97e-194 560.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_126347_4 1385658.U5KNR1_9VIRU 1.73e-66 219.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_17892_2 1121448.DGI_2307 2.46e-07 59.3 COG0859@1|root,COG0859@2|Bacteria,1NABN@1224|Proteobacteria,42V15@68525|delta/epsilon subdivisions,2WRJN@28221|Deltaproteobacteria,2MA6E@213115|Desulfovibrionales 28221|Deltaproteobacteria M PFAM glycosyl transferase family 9 - - - - - - - - - - - - Glyco_transf_9 k59_34950_1 335284.Pcryo_1290 1.53e-103 335.0 COG1330@1|root,COG1330@2|Bacteria,1MWTI@1224|Proteobacteria,1RNT0@1236|Gammaproteobacteria,3NM1F@468|Moraxellaceae 1236|Gammaproteobacteria L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity recC GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008854,GO:0009314,GO:0009338,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016887,GO:0016895,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044355,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0099046,GO:0140097,GO:1901360,GO:1902494 3.1.11.5 ko:K03583 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_V_gamma k59_134576_1 595460.RRSWK_06944 3.4e-22 92.8 2A5SH@1|root,30UHM@2|Bacteria,2J3VX@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - k59_142929_1 2003327.CAPSD_BPCHP 1.59e-34 131.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_142929_2 105154.Q9MBU3_9VIRU 3.11e-09 62.0 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_68015_2 1042375.AFPL01000014_gene2226 9.66e-236 663.0 COG5511@1|root,COG5511@2|Bacteria,1MVN4@1224|Proteobacteria,1RZ6N@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage portal protein, lambda family - - - - - - - - - - - - Phage_portal_2 k59_68015_3 1042375.AFPL01000014_gene2225 0.0 918.0 COG3087@1|root,COG3087@2|Bacteria,1QU07@1224|Proteobacteria,1T1JT@1236|Gammaproteobacteria 1236|Gammaproteobacteria D Mu-like prophage major head subunit gpT - - - - - - - - - - - - Mu-like_gpT k59_68015_4 439375.Oant_1503 1.18e-19 84.3 COG5471@1|root,COG5471@2|Bacteria,1NDRS@1224|Proteobacteria,2U97N@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Uncharacterized conserved protein (DUF2190) - - - - - - - - - - - - DUF2190 k59_68015_8 1042375.AFPL01000014_gene2220 2e-41 138.0 COG0234@1|root,COG0234@2|Bacteria 2|Bacteria O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 k59_68015_10 1042375.AFPL01000014_gene2218 2.65e-113 332.0 2D80K@1|root,32TQ4@2|Bacteria,1N4HE@1224|Proteobacteria,1SC5V@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_68015_11 1042375.AFPL01000014_gene2217 2.34e-238 752.0 COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria 2|Bacteria D nuclear chromosome segregation - - - - - - - - - - - - PhageMin_Tail,TMP_2 k59_68015_12 1042375.AFPL01000014_gene2216 4.74e-53 170.0 2E491@1|root,32Z4T@2|Bacteria,1N7AX@1224|Proteobacteria,1SE0N@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_68015_14 1042375.AFPL01000042_gene3834 2.89e-86 293.0 2DB8F@1|root,2Z7RQ@2|Bacteria,1NA57@1224|Proteobacteria,1RQ25@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_68015_15 595494.Tola_0752 5.52e-99 327.0 2DB8F@1|root,2Z7RQ@2|Bacteria,1NA57@1224|Proteobacteria,1RR9Y@1236|Gammaproteobacteria,1Y594@135624|Aeromonadales 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_68015_17 1042375.AFPL01000053_gene1450 7.15e-137 425.0 2CFVD@1|root,2Z7PU@2|Bacteria,1PVM9@1224|Proteobacteria,1S0UF@1236|Gammaproteobacteria,46AB5@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_242098_1 1210884.HG799467_gene13131 1.48e-59 199.0 COG0553@1|root,COG0553@2|Bacteria 2|Bacteria L helicase activity - - - - - - - - - - - - Helicase_C,N6_N4_Mtase,SNF2_N k59_92928_1 1278078.G419_25292 1.46e-07 53.9 28JC4@1|root,2Z96S@2|Bacteria,2IEPB@201174|Actinobacteria,4G3UP@85025|Nocardiaceae 201174|Actinobacteria S P22 coat protein-protein 5 domain protein - - - - - - - - - - - - P22_CoatProtein k59_9936_3 574966.KB898655_gene1599 1.15e-61 205.0 COG4128@1|root,COG4128@2|Bacteria,1REHG@1224|Proteobacteria,1S491@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Zonular occludens toxin (Zot) - - - - - - - - - - - - Zot k59_9936_5 1215092.PA6_046_00270 9.82e-17 73.2 28QDM@1|root,2ZCVZ@2|Bacteria,1P5MR@1224|Proteobacteria,1SW6Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_9936_6 1166016.W5S_2328 4.77e-145 422.0 2CI0W@1|root,2Z81W@2|Bacteria,1R9FZ@1224|Proteobacteria,1S0NA@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage X family - - - - - - - - - - - - Phage_CRI,Phage_X k59_209350_1 1692259.A0A0K1RL59_9CIRC 3.09e-22 97.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_159751_1 411460.RUMTOR_01335 7.67e-120 395.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_192723_1 291607.REP6_SCSVF 2.56e-17 84.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_68752_3 994573.T472_0208830 1.94e-11 70.9 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,2487V@186801|Clostridia,36EDD@31979|Clostridiaceae 186801|Clostridia L DNA polymerase - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_2864_1 1986029.Q9MBM8_9VIRU 4.77e-16 77.4 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_259838_1 1235800.C819_03834 4.96e-33 131.0 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,2487V@186801|Clostridia,27JEU@186928|unclassified Lachnospiraceae 186801|Clostridia L DNA polymerase A domain - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_60249_1 1476888.X4Y7Z1_9CAUD 6.77e-59 192.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_144018_2 547042.BACCOPRO_02118 2.82e-08 55.5 2EYVT@1|root,33S2W@2|Bacteria,4P0XD@976|Bacteroidetes,2FR7P@200643|Bacteroidia,4AM24@815|Bacteroidaceae 976|Bacteroidetes - - - - - - - - - - - - - - DUF4866 k59_68916_1 225937.HP15_3095 8.07e-91 275.0 COG4128@1|root,COG4128@2|Bacteria,1N0I7@1224|Proteobacteria,1SAH8@1236|Gammaproteobacteria,46BMP@72275|Alteromonadaceae 1236|Gammaproteobacteria S Zonular occludens toxin (Zot) zot GO:0001906,GO:0006810,GO:0006996,GO:0007010,GO:0008150,GO:0009405,GO:0009987,GO:0016043,GO:0031640,GO:0035821,GO:0042044,GO:0042045,GO:0044364,GO:0044419,GO:0051179,GO:0051234,GO:0051704,GO:0070633,GO:0071840 - ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko02042 - - - Zot k59_259978_2 186617.M9M8L2_9VIRU 6.01e-43 153.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_234287_1 563192.HMPREF0179_03460 6.91e-50 178.0 COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1PZ6S@1224|Proteobacteria,42YZ3@68525|delta/epsilon subdivisions,2WU0W@28221|Deltaproteobacteria,2MAW9@213115|Desulfovibrionales 28221|Deltaproteobacteria L Toprim-like - - - - - - - - - - - - DnaB_C,Toprim_2 k59_259979_1 465817.ETA_24250 4.96e-07 55.8 2EB6P@1|root,3357C@2|Bacteria,1R523@1224|Proteobacteria,1RYG9@1236|Gammaproteobacteria 1236|Gammaproteobacteria S ORF6N domain - - - - - - - - - - - - ORF6N k59_44127_1 1265505.ATUG01000002_gene2563 1.58e-19 102.0 COG0454@1|root,COG0503@1|root,COG1040@1|root,COG0456@2|Bacteria,COG0503@2|Bacteria,COG1040@2|Bacteria,1QV41@1224|Proteobacteria,42Q37@68525|delta/epsilon subdivisions,2WKE3@28221|Deltaproteobacteria,2MMN4@213118|Desulfobacterales 28221|Deltaproteobacteria K competence protein - - - - - - - - - - - - - k59_93594_1 1122194.AUHU01000013_gene665 2.64e-70 223.0 COG4128@1|root,COG4128@2|Bacteria,1REHG@1224|Proteobacteria,1S491@1236|Gammaproteobacteria,46BRE@72275|Alteromonadaceae 1236|Gammaproteobacteria S Zonular occludens toxin (Zot) - - - - - - - - - - - - Zot k59_210441_2 1118054.CAGW01000095_gene4680 6.77e-10 59.7 2EI4V@1|root,33BW7@2|Bacteria,1VKQH@1239|Firmicutes,4HRPN@91061|Bacilli 91061|Bacilli S Protein of unknwon function (DUF3310) - - - - - - - - - - - - DUF3310 k59_210441_3 1166948.JPZL01000001_gene3142 1.82e-16 87.0 COG1061@1|root,COG1061@2|Bacteria,1MV9F@1224|Proteobacteria,1RNAN@1236|Gammaproteobacteria,1XH5K@135619|Oceanospirillales 135619|Oceanospirillales L helicase superfamily c-terminal domain - - - ko:K19789 - - - - ko00000,ko03400 - - - Helicase_C,ResIII k59_220357_1 426117.M446_0678 4e-13 74.3 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2TRJF@28211|Alphaproteobacteria,1JTT7@119045|Methylobacteriaceae 28211|Alphaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_161152_1 323848.Nmul_A1463 1.76e-41 152.0 COG1783@1|root,COG1783@2|Bacteria,1R66A@1224|Proteobacteria,2VN61@28216|Betaproteobacteria,372UI@32003|Nitrosomonadales 28216|Betaproteobacteria S Phage terminase large subunit - - - ko:K06909 - - - - ko00000 - - - Terminase_3 k59_120272_1 160488.PP_2270 1.1e-89 280.0 COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1QWI1@1224|Proteobacteria,1RZ7K@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Toprim-like - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - AAA_25,DnaB_C,Toprim_2 k59_70174_1 411460.RUMTOR_02024 1.35e-48 165.0 2A0KC@1|root,30NQJ@2|Bacteria,1V3K4@1239|Firmicutes,24HYK@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_29104_3 387092.NIS_1675 1.75e-09 68.6 COG1061@1|root,COG1061@2|Bacteria,1PPY3@1224|Proteobacteria,43AP9@68525|delta/epsilon subdivisions 1224|Proteobacteria L SNF2 family N-terminal domain - - - - - - - - - - - - ERCC3_RAD25_C,Helicase_C,PLDc_2,ResIII k59_29104_6 997350.HMPREF9129_1672 2.9e-55 183.0 2CAZB@1|root,2Z9VC@2|Bacteria,1VAG9@1239|Firmicutes,24DBS@186801|Clostridia 186801|Clostridia S AAA domain - - - - - - - - - - - - AAA_24 k59_36702_1 1193181.BN10_650005 5.23e-15 73.9 COG2131@1|root,COG2131@2|Bacteria,2IJ94@201174|Actinobacteria,4FHCM@85021|Intrasporangiaceae 201174|Actinobacteria F MafB19-like deaminase - - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 k59_128876_1 313606.M23134_00538 1.78e-05 51.2 COG0729@1|root,COG0729@2|Bacteria,4NVBC@976|Bacteroidetes 976|Bacteroidetes M Chaperone of endosialidase - - - - - - - - - - - - Peptidase_S74 k59_128876_2 188350.Q8H9S6_9CAUD 1.31e-28 114.0 4QGE6@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_128876_3 1054968.G0X4V1_9CAUD 1.16e-28 122.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QNI0@10744|Podoviridae 10744|Podoviridae S viral capsid - GO:0003674,GO:0005488,GO:0005515,GO:0042802 - - - - - - - - - - - k59_210525_2 225937.HP15_1954 2.25e-32 140.0 COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,1R97W@1224|Proteobacteria,1RTIA@1236|Gammaproteobacteria,469KR@72275|Alteromonadaceae 1236|Gammaproteobacteria D Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_171382_1 1609634.A0A0C5AFV4_9VIRU 1.31e-90 288.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_171382_2 1609634.A0A0C5ANA6_9VIRU 3.11e-22 96.7 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_171382_4 1609634.A0A0C5AFT2_9VIRU 7.3e-117 348.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_171382_6 186617.M9M8L2_9VIRU 2.33e-57 193.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_179184_1 1037409.BJ6T_37290 1.96e-43 157.0 COG2227@1|root,COG2227@2|Bacteria,1QU62@1224|Proteobacteria,2TW17@28211|Alphaproteobacteria,3K6P1@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H C-methyltransferase C-terminal domain - - - - - - - - - - - - Methyltransf_13,Methyltransf_14,Methyltransf_23 k59_20805_14 691965.D4P7I3_9CAUD 4.51e-242 718.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_162313_1 1476391.X5KCE1_9CAUD 1.3e-166 495.0 4QF3C@10239|Viruses,4QWIA@35237|dsDNA viruses no RNA stage,4QU4U@28883|Caudovirales,4QNNQ@10744|Podoviridae 10744|Podoviridae S host cell wall - - - - - - - - - - - - - k59_113536_1 478749.BRYFOR_08554 8.04e-44 154.0 COG0553@1|root,COG0553@2|Bacteria,1TS9W@1239|Firmicutes,24CGX@186801|Clostridia 186801|Clostridia KL Helicase conserved C-terminal domain - - - - - - - - - - - - - k59_171391_1 1692258.A0A0K1RL51_9CIRC 2e-27 108.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_20938_1 1788444.A0A190WHA5_9CIRC 1.59e-07 58.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_30637_1 105154.Q9MBU6_9VIRU 9.95e-71 230.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_113726_1 1609634.A0A0C5AFV4_9VIRU 4.47e-132 393.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_47290_2 1458275.AZ34_10360 8.74e-46 155.0 2EKAP@1|root,33E0Y@2|Bacteria,1NAAI@1224|Proteobacteria,2VZTN@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_237586_1 232346.JHQL01000007_gene1913 6.63e-51 179.0 28JT0@1|root,2Z9IB@2|Bacteria,1R5B0@1224|Proteobacteria,1S0EH@1236|Gammaproteobacteria,1XJ7V@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k59_148558_3 2003327.CAPSD_BPCHP 5.08e-17 82.8 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_173060_1 714961.BFZC1_10702 1.41e-12 72.0 COG3935@1|root,COG3935@2|Bacteria,1TPPF@1239|Firmicutes,4HNK6@91061|Bacilli,3IZ17@400634|Lysinibacillus 91061|Bacilli L primosome component and related proteins - - - - - - - - - - - - DnaB_2,Phg_2220_C k59_96881_1 1692244.A0A0K1RLR5_9CIRC 2.96e-06 54.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_189544_1 351348.Maqu_4285 8.02e-06 48.5 COG0553@1|root,COG0553@2|Bacteria,1MV6M@1224|Proteobacteria,1RQ34@1236|Gammaproteobacteria,466BB@72275|Alteromonadaceae 1236|Gammaproteobacteria L SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,Mrr_cat,SNF2_N k59_32072_1 1273707.L7TIC4_9CAUD 3.8e-34 121.0 4QFPC@10239|Viruses,4QXCG@35237|dsDNA viruses no RNA stage,4QPQC@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_7652_1 1027292.HMPREF9372_3397 6.07e-23 104.0 COG1196@1|root,COG1196@2|Bacteria,1TQY7@1239|Firmicutes,4HCRF@91061|Bacilli,26ENV@186818|Planococcaceae 91061|Bacilli D nuclear chromosome segregation - - - - - - - - - - - - AAA_23,AAA_27 k59_131500_2 1165094.RINTHH_3920 8.95e-61 202.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_131500_3 1609634.A0A0C5AK24_9VIRU 1.62e-09 57.0 4QCC5@10239|Viruses,4QUKW@29258|ssDNA viruses,4QP4C@10841|Microviridae 10841|Microviridae S viral process - - - - - - - - - - - - - k59_131500_4 1385658.U5KPZ6_9VIRU 3.93e-219 623.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_131500_6 1986029.Q9MBM6_9VIRU 6.1e-15 74.7 4QDBB@10239|Viruses,4QUM0@29258|ssDNA viruses,4QP4D@10841|Microviridae 10841|Microviridae S Chlamydia-phage Chp2 scaffold (Chlamy_scaf) - - - - - - - - - - - - - k59_190338_1 1547445.LO80_03300 7.27e-17 83.2 COG1783@1|root,COG1783@2|Bacteria,1MWGP@1224|Proteobacteria,1S8D6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C k59_132039_1 1618248.A0A0C5IB82_9CIRC 4.82e-59 198.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_14701_1 2003327.CAPSD_BPCHP 1.53e-19 99.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_88411_1 1165094.RINTHH_3920 3.39e-58 192.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_181337_1 765698.Mesci_3833 0.000436 48.1 COG4675@1|root,COG4675@2|Bacteria,1QWQH@1224|Proteobacteria,2UUR5@28211|Alphaproteobacteria 28211|Alphaproteobacteria S tail collar domain protein - - - - - - - - - - - - Collar k59_149265_5 145579.CAPSD_BPPHM 5.63e-59 210.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_149265_7 1986029.Q9MBM3_9VIRU 1.09e-21 99.4 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_156764_1 1027273.GZ77_20645 1.72e-13 71.6 COG0847@1|root,COG0847@2|Bacteria,1R9YS@1224|Proteobacteria,1S23K@1236|Gammaproteobacteria 1236|Gammaproteobacteria L 3' exoribonuclease, RNase T-like - - - ko:K10906 - - - - ko00000,ko01000,ko03400 - - - DUF5051,Exonuc_VIII k59_156764_2 551790.B5BTW0_9CAUD 3.81e-20 89.0 4QE7X@10239|Viruses,4QVF0@35237|dsDNA viruses no RNA stage,4QPUM@28883|Caudovirales,4QP17@10744|Podoviridae 10744|Podoviridae S Cytidine and deoxycytidylate deaminase zinc-binding region - - - - - - - - - - - - - k59_156764_7 1120936.KB907208_gene1107 7.68e-162 478.0 COG0209@1|root,COG0209@2|Bacteria,2IC1H@201174|Actinobacteria 201174|Actinobacteria F Ribonucleotide reductase, barrel domain - - - - - - - - - - - - Ribonuc_red_lgC k59_33072_1 1385658.U5KPZ6_9VIRU 2.41e-26 112.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_115922_1 1320556.AVBP01000003_gene3945 5.9e-23 103.0 COG1475@1|root,COG1475@2|Bacteria,1MVF9@1224|Proteobacteria,2TR0P@28211|Alphaproteobacteria 28211|Alphaproteobacteria K ParB domain protein nuclease - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_64235_2 136993.KB900626_gene1843 3.76e-11 67.4 COG4725@1|root,COG4725@2|Bacteria,1R553@1224|Proteobacteria,2TRP6@28211|Alphaproteobacteria,36XZ4@31993|Methylocystaceae 28211|Alphaproteobacteria KT MT-A70 - - - - - - - - - - - - MT-A70,ParBc k59_16174_2 203124.Tery_3529 2.28e-20 90.5 COG0457@1|root,COG1262@1|root,COG0457@2|Bacteria,COG1262@2|Bacteria,1GQW8@1117|Cyanobacteria,1H81P@1150|Oscillatoriales 1117|Cyanobacteria S Sulfatase-modifying factor enzyme 1 - - - - - - - - - - - - FGE-sulfatase,TPR_1,TPR_8 k59_264999_2 1788439.A0A190WHD0_9CIRC 1.19e-30 127.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_89338_1 411459.RUMOBE_01049 2.6e-55 190.0 COG0507@1|root,COG0507@2|Bacteria,1TQWH@1239|Firmicutes,24A8I@186801|Clostridia 186801|Clostridia L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD - - - - - - - - - - - - - k59_165711_1 1538804.A0A088F7W8_9CAUD 2.94e-09 57.4 4QAR1@10239|Viruses,4QPJE@28883|Caudovirales 28883|Caudovirales S ATPase activity - - - - - - - - - - - - - k59_165711_2 1122201.AUAZ01000017_gene2949 2.15e-81 256.0 COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,1RXX2@1236|Gammaproteobacteria,46B9P@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative metallopeptidase domain - - - - - - - - - - - - DUF2201,DUF2201_N k59_98677_1 942016.E9NIH1_9CAUD 1.32e-41 146.0 4QEMD@10239|Viruses,4R0JN@35237|dsDNA viruses no RNA stage,4QUGF@28883|Caudovirales,4QNXF@10744|Podoviridae 10744|Podoviridae S AAA domain - - - - - - - - - - - - - k59_65698_1 933262.AXAM01000071_gene2218 9.93e-18 85.1 28XPA@1|root,2ZJK5@2|Bacteria,1P9T2@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_215151_1 1232410.KI421412_gene256 1.99e-28 116.0 COG0500@1|root,COG0500@2|Bacteria,1MVD1@1224|Proteobacteria 1224|Proteobacteria Q methyltransferase - - - - - - - - - - - - Methyltransf_13,Methyltransf_14,Methyltransf_23 k59_215153_1 1041142.ATTP01000043_gene5294 6.55e-16 78.6 28PTM@1|root,2ZCIH@2|Bacteria,1RBCN@1224|Proteobacteria,2VGPG@28211|Alphaproteobacteria,4BDH5@82115|Rhizobiaceae 28211|Alphaproteobacteria S Family of unknown function (DUF5309) - - - - - - - - - - - - DUF5309 k59_215153_2 1524880.A0A076G697_9VIRU 1.24e-06 57.4 4QD1M@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_239993_1 1279017.AQYJ01000026_gene265 5.31e-57 190.0 COG0438@1|root,COG0438@2|Bacteria,1NA28@1224|Proteobacteria,1RQBV@1236|Gammaproteobacteria,4668K@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0438 Glycosyltransferase - - - - - - - - - - - - DUF3524,Glyco_trans_1_4,Glycos_transf_1 k59_198781_2 1262538.R9R2G2_9CAUD 0.00096 47.0 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales 28883|Caudovirales S HNH endonuclease - - - - - - - - - - - - - k59_239996_1 91464.S7335_1186 1.32e-115 346.0 2CC4J@1|root,2Z7W8@2|Bacteria,1G4C9@1117|Cyanobacteria 1117|Cyanobacteria S Domain of unknown function (DUF932) - - - - - - - - - - - - DUF932 k59_98857_1 1122201.AUAZ01000017_gene2947 2.39e-25 105.0 COG0749@1|root,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,465DD@72275|Alteromonadaceae 1236|Gammaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity - - - - - - - - - - - - DNA_pol_A k59_98857_3 1416009.V9VCX5_9CAUD 4.91e-100 305.0 4QEG2@10239|Viruses,4QVSD@35237|dsDNA viruses no RNA stage,4QRJ9@28883|Caudovirales,4QP0R@10744|Podoviridae 10744|Podoviridae S exonuclease activity - - - - - - - - - - - - - k59_98857_4 1416009.V9VHP3_9CAUD 0.0 922.0 4QGA5@10239|Viruses,4QURD@35237|dsDNA viruses no RNA stage,4QT9N@28883|Caudovirales,4QP47@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_98857_5 942016.E9NIH1_9CAUD 4.29e-94 283.0 4QEMD@10239|Viruses,4R0JN@35237|dsDNA viruses no RNA stage,4QUGF@28883|Caudovirales,4QNXF@10744|Podoviridae 10744|Podoviridae S AAA domain - - - - - - - - - - - - - k59_98857_6 1051675.G0YQG6_9CAUD 4.65e-56 186.0 4QD9V@10239|Viruses,4QYQ1@35237|dsDNA viruses no RNA stage,4QTHS@28883|Caudovirales,4QP1H@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_98857_7 1123227.KB899334_gene1667 7.88e-21 90.9 COG0817@1|root,COG0817@2|Bacteria,1NDKU@1224|Proteobacteria,2UFCY@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group ruvC - 3.1.22.4 ko:K01159 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - - k59_116623_1 1609634.A0A0C5AFT2_9VIRU 2.62e-31 122.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_50218_1 490913.C4NTE0_9CAUD 3.38e-38 148.0 4QAXA@10239|Viruses,4QYJI@35237|dsDNA viruses no RNA stage,4QQ1A@28883|Caudovirales,4QNU7@10744|Podoviridae 10744|Podoviridae S metallopeptidase activity - - - - - - - - - - - - - k59_166350_2 444875.E3SMD8_9CAUD 2.02e-55 177.0 4QD0J@10239|Viruses,4R0A5@35237|dsDNA viruses no RNA stage,4QSK9@28883|Caudovirales,4QNR4@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_83431_5 145579.CAPSD_BPPHM 1.86e-65 228.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_232727_1 1234888.K0A2J2_9VIRU 5.49e-38 145.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_257650_1 443152.MDG893_20559 9.71e-83 281.0 COG2911@1|root,COG2911@2|Bacteria,1QU6S@1224|Proteobacteria,1S7WY@1236|Gammaproteobacteria 1236|Gammaproteobacteria D tail tape measure protein - - - - - - - - - - - - SLT,Tape_meas_lam_C k59_216212_1 279714.FuraDRAFT_1478 6.03e-27 115.0 COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,2VPJ0@28216|Betaproteobacteria 28216|Betaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_3,Phage_integrase k59_33740_4 1234888.K0A2J2_9VIRU 4.62e-173 503.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_33740_5 1234888.K0A2R8_9VIRU 7.5e-44 156.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_50223_1 1274524.BSONL12_04689 9.45e-09 61.6 COG5283@1|root,COG5283@2|Bacteria,1UHQM@1239|Firmicutes,4HGW7@91061|Bacilli,1ZBWW@1386|Bacillus 91061|Bacilli D phage tail tape measure protein - - - - - - - - - - - - Peptidase_M23,PhageMin_Tail,Sipho_tail k59_91754_3 1609634.A0A0C5ANA6_9VIRU 3.76e-24 102.0 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_66832_1 1556290.A0A0A0RQH0_9CAUD 2.39e-45 171.0 4QAK6@10239|Viruses,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_108307_5 762376.AXYL_04643 8.61e-28 111.0 COG3756@1|root,COG3756@2|Bacteria,1N7P7@1224|Proteobacteria,2VWCV@28216|Betaproteobacteria 28216|Betaproteobacteria S Protein of unknown function (DUF1376) - - - - - - - - - - - - DUF1376 k59_125042_1 742740.HMPREF9474_02303 5.01e-253 751.0 2EWZQ@1|root,33QB0@2|Bacteria,1V0T1@1239|Firmicutes,249Z2@186801|Clostridia,221YV@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_257662_1 1004785.AMBLS11_04835 6.12e-12 70.9 28K7U@1|root,2Z9VT@2|Bacteria,1RFB2@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_249287_7 475178.B2BTN9_9CAUD 0.000289 43.1 4QB9J@10239|Viruses,4QXFE@35237|dsDNA viruses no RNA stage,4QS1Z@28883|Caudovirales,4QN8F@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_50230_2 428125.CLOLEP_01417 1.89e-16 77.0 2CGG9@1|root,2ZVSJ@2|Bacteria,1V633@1239|Firmicutes,24HD0@186801|Clostridia,3WMXK@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_125043_1 1120963.KB894501_gene316 2.67e-10 60.8 COG2852@1|root,COG2852@2|Bacteria,1N7EJ@1224|Proteobacteria,1SF5D@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - DUF559 k59_133335_1 1175654.A0A0S0NAG1_9CAUD 7.59e-34 119.0 4QAQV@10239|Viruses,4QUPK@35237|dsDNA viruses no RNA stage,4QPCB@28883|Caudovirales 28883|Caudovirales S protein disulfide oxidoreductase activity - - - - - - - - - - - - - k59_25616_1 105154.Q9MBU6_9VIRU 2.81e-74 245.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_17635_9 1116375.VEJY3_09500 1.48e-57 188.0 291VY@1|root,2ZPFN@2|Bacteria,1P4BG@1224|Proteobacteria,1SUJ6@1236|Gammaproteobacteria,1XXNJ@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k59_17635_11 310539.Q5G7M2_9CAUD 1.21e-11 77.4 4QAY9@10239|Viruses,4QWGZ@35237|dsDNA viruses no RNA stage,4QRJC@28883|Caudovirales,4QMNM@10699|Siphoviridae 10699|Siphoviridae S hydrolase activity, acting on acid anhydrides - - - - - - - - - - - - - k59_17635_13 755731.Clo1100_3566 1.15e-20 100.0 COG2887@1|root,COG2887@2|Bacteria,1TPIC@1239|Firmicutes,247TB@186801|Clostridia,36EZ3@31979|Clostridiaceae 186801|Clostridia L Protein of unknown function (DUF2800) - - - - - - - - - - - - DUF2800 k59_17635_15 936154.STP_0866 2.65e-20 91.3 28J2E@1|root,2Z8YX@2|Bacteria,1TRF9@1239|Firmicutes,4HKAQ@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF2815) - - - - - - - - - - - - DUF2815 k59_17635_16 1211115.ALIQ01000188_gene622 2.66e-101 332.0 COG0749@1|root,COG0749@2|Bacteria,1MWX7@1224|Proteobacteria,2UNT9@28211|Alphaproteobacteria 28211|Alphaproteobacteria L COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A,DNA_pol_A_exo1 k59_17635_17 742743.HMPREF9453_00576 1.46e-107 333.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4H2W4@909932|Negativicutes 909932|Negativicutes L SNF2 family - - - - - - - - - - - - Helicase_C,SNF2_N k59_17635_18 1096546.WYO_0205 8.87e-30 113.0 COG0647@1|root,COG0647@2|Bacteria 2|Bacteria G UMP catabolic process nagD - 2.7.1.25,3.1.3.41 ko:K00860,ko:K01101 ko00230,ko00627,ko00920,ko01100,ko01120,map00230,map00627,map00920,map01100,map01120 M00176 R00509,R03024,R04928 RC00002,RC00078,RC00151 ko00000,ko00001,ko00002,ko01000 - - - Hydrolase_6,Hydrolase_like k59_17635_20 411468.CLOSCI_00223 6.16e-10 59.7 2E38J@1|root,32Y88@2|Bacteria,1VAXK@1239|Firmicutes,24N7K@186801|Clostridia,221KQ@1506553|Lachnoclostridium 186801|Clostridia S COG NOG18350 non supervised orthologous group - - - - - - - - - - - - VRR_NUC k59_167537_8 1173026.Glo7428_1500 2.2e-08 64.7 COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,1G4RW@1117|Cyanobacteria 1117|Cyanobacteria KL PFAM ParB-like nuclease domain - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - N6_N4_Mtase,ParBc k59_84333_3 1379858.N508_00306 2.33e-60 201.0 COG0863@1|root,COG0863@2|Bacteria,2GGPV@200930|Deferribacteres 200930|Deferribacteres L DNA methylase - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_175428_1 583345.Mmol_1800 0.000186 45.8 COG2197@1|root,COG2197@2|Bacteria,1RG6R@1224|Proteobacteria,2VRUT@28216|Betaproteobacteria,2KKJV@206350|Nitrosomonadales 206350|Nitrosomonadales K TIGRFAM transcriptional regulator EpsA - - - - - - - - - - - - GerE k59_34805_1 1209072.ALBT01000031_gene1886 1.3e-21 109.0 COG2372@1|root,COG3209@1|root,COG2372@2|Bacteria,COG3209@2|Bacteria 2|Bacteria M self proteolysis - - - ko:K07156 - - - - ko00000,ko02000 9.B.62.2 - - Big_5,DUF4082,SLH k59_150993_2 1121890.AUDO01000003_gene1788 2.9e-31 122.0 COG0692@1|root,COG0692@2|Bacteria,4NE2B@976|Bacteroidetes,1I83B@117743|Flavobacteriia,2NSB0@237|Flavobacterium 976|Bacteroidetes L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine ung GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k59_250679_1 1121859.KB890750_gene319 1.42e-13 71.6 2DT8X@1|root,32UUQ@2|Bacteria,4NSYW@976|Bacteroidetes,47SF7@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_250679_2 1127673.GLIP_3386 2.37e-09 57.8 2AD08@1|root,312N7@2|Bacteria,1NDC4@1224|Proteobacteria 1224|Proteobacteria S Holin of 3TMs, for gene-transfer release - - - - - - - - - - - - GTA_holin_3TM k59_209170_3 1385658.U5KNR1_9VIRU 2.81e-68 221.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_84801_1 360910.BAV0413 5.93e-29 115.0 COG3756@1|root,COG3756@2|Bacteria,1N7P7@1224|Proteobacteria,2VWCV@28216|Betaproteobacteria,3T73Q@506|Alcaligenaceae 28216|Betaproteobacteria S Protein of unknown function (DUF1376) - - - - - - - - - - - - DUF1376 k59_110260_1 1379788.I0CKB2_9VIRU 6.91e-15 80.9 4QD5V@10239|Viruses 10239|Viruses S Viral coat protein (S domain) - GO:0003674,GO:0003676,GO:0003723,GO:0005198,GO:0005488,GO:0005509,GO:0005575,GO:0008289,GO:0019012,GO:0019028,GO:0019030,GO:0039617,GO:0039660,GO:0043167,GO:0043169,GO:0044423,GO:0046872,GO:0097159,GO:1901363 - - - - - - - - - - - k59_135280_1 1121381.JNIV01000036_gene3370 9.97e-35 135.0 COG0675@1|root,COG0675@2|Bacteria,1WJ2V@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus L Probable transposase - - - ko:K07496 - - - - ko00000 - - - HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon k59_151924_1 313596.RB2501_01425 2.17e-15 80.1 COG5545@1|root,COG5545@2|Bacteria,4PMA3@976|Bacteroidetes,1IJP7@117743|Flavobacteriia 976|Bacteroidetes L VirE N-terminal domain - - - - - - - - - - - - DUF3987,PriCT_2,VirE,VirE_N k59_151924_2 435591.BDI_0861 3.46e-13 68.2 COG0270@1|root,COG0270@2|Bacteria,4NJPP@976|Bacteroidetes,2FKYT@200643|Bacteroidia 976|Bacteroidetes H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_184652_1 1449338.JQLU01000005_gene2934 1.19e-26 108.0 COG0022@1|root,COG0022@2|Bacteria,1TP3J@1239|Firmicutes,4HAP6@91061|Bacilli,27H0J@186828|Carnobacteriaceae 91061|Bacilli C Transketolase, pyrimidine binding domain acoB - 1.2.4.1 ko:K00162,ko:K21417 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C k59_27565_1 1078085.HMPREF1210_02518 0.000363 45.4 COG1595@1|root,COG1595@2|Bacteria,1VB1T@1239|Firmicutes,4HI78@91061|Bacilli,26FR4@186818|Planococcaceae 91061|Bacilli K Sigma-70, region 4 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k59_184665_1 1788452.A0A190WHG0_9CIRC 7.45e-11 63.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_143745_2 1692256.A0A0K1RL85_9CIRC 1.13e-76 243.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_111532_2 76869.PputGB1_1746 6.22e-150 445.0 COG0507@1|root,COG0507@2|Bacteria,1R1AT@1224|Proteobacteria,1RS66@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Participates in initiation and elongation during chromosome replication - - - - - - - - - - - - - k59_19407_1 1385658.U5KPZ6_9VIRU 4.86e-141 418.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_69729_1 1385658.U5KPZ6_9VIRU 1.36e-87 276.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_78141_1 666684.AfiDRAFT_1861 1.45e-33 132.0 28JTG@1|root,2Z9IR@2|Bacteria,1R0GC@1224|Proteobacteria,2TURR@28211|Alphaproteobacteria,3JUCC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF2793) - - - - - - - - - - - - DUF2793 k59_210187_2 1121943.KB900008_gene1987 3.15e-46 172.0 2DZHM@1|root,32VAY@2|Bacteria,1N0DC@1224|Proteobacteria,1SP9I@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_153168_1 563192.HMPREF0179_03457 3.27e-65 218.0 COG0749@1|root,COG0749@2|Bacteria,1P27P@1224|Proteobacteria,42YUP@68525|delta/epsilon subdivisions,2WTS1@28221|Deltaproteobacteria,2MAPB@213115|Desulfovibrionales 28221|Deltaproteobacteria L DNA polymerase A domain - - - - - - - - - - - - DNA_pol_A k59_193662_1 1609634.A0A0C5AFV4_9VIRU 2.05e-47 169.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_177506_2 479437.Elen_2014 3.65e-17 86.7 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2GJY2@201174|Actinobacteria,4CUSF@84998|Coriobacteriia 84998|Coriobacteriia L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A k59_178926_1 1556290.A0A0A0RM05_9CAUD 5.44e-71 231.0 4QAYV@10239|Viruses,4QPU3@28883|Caudovirales,4QKKX@10699|Siphoviridae 10699|Siphoviridae S Phage portal protein - - - - - - - - - - - - - k59_161995_1 1385658.U5KPZ6_9VIRU 5.53e-85 267.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_187290_1 402612.FP2177 1.13e-68 226.0 COG0714@1|root,COG0714@2|Bacteria,4NJMT@976|Bacteroidetes,1HZMP@117743|Flavobacteriia 976|Bacteroidetes S AAA domain (dynein-related subfamily) - - 6.6.1.2 ko:K09882 ko00860,ko01100,map00860,map01100 - R05227 RC02000 ko00000,ko00001,ko01000 - - - AAA_5 k59_221624_1 443152.MDG893_20574 1.41e-35 125.0 2CHRA@1|root,32S6D@2|Bacteria,1MZ8I@1224|Proteobacteria,1SHSQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage tail assembly chaperone, TAC - - - - - - - - - - - - Phage_TAC_13 k59_146865_1 259536.Psyc_1439 3.9e-65 219.0 COG0715@1|root,COG4191@1|root,COG0715@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RNNF@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Histidine kinase ttrS - 2.7.13.3 ko:K13040 ko02020,map02020 M00514 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,Phosphonate-bd k59_30335_2 1609634.A0A0C5AFT2_9VIRU 9.57e-99 297.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_262208_1 1403819.BATR01000162_gene5299 1.5e-88 282.0 COG0305@1|root,COG0305@2|Bacteria,46SKM@74201|Verrucomicrobia,2ITGD@203494|Verrucomicrobiae 203494|Verrucomicrobiae L DnaB-like helicase C terminal domain - - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_221796_1 1121382.JQKG01000014_gene268 2.23e-25 107.0 COG4675@1|root,COG4675@2|Bacteria 2|Bacteria M tail collar domain protein - - - - - - - - - - - - Collar k59_95547_1 573.JG24_02360 7.81e-15 75.5 COG4734@1|root,COG4734@2|Bacteria,1RGJX@1224|Proteobacteria,1S45W@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Antirestriction protein (ArdA) - - - - - - - - - - - - ArdA k59_130063_1 1114964.L485_16325 1.57e-42 152.0 COG0270@1|root,COG0270@2|Bacteria 2|Bacteria L DNA (cytosine-5-)-methyltransferase activity ydiP - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_171292_1 335283.Neut_1455 2.01e-35 139.0 COG2304@1|root,COG4733@1|root,COG2304@2|Bacteria,COG4733@2|Bacteria,1MXB4@1224|Proteobacteria,2VJS7@28216|Betaproteobacteria 28216|Betaproteobacteria M Putative phage tail protein - - - - - - - - - - - - Phage-tail_3 k59_46944_1 537971.HCCG_01555 1.07e-109 330.0 COG0535@1|root,COG0535@2|Bacteria,1PHAQ@1224|Proteobacteria,42QIE@68525|delta/epsilon subdivisions,2YNUJ@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria C Iron-sulfur cluster-binding domain - - - - - - - - - - - - Radical_SAM,SPASM k59_71369_1 1391032.T1YRW9_9VIRU 2.29e-16 80.9 4QB6C@10239|Viruses 10239|Viruses L Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_146876_1 2003327.CAPSD_BPCHP 1.71e-24 108.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_187530_2 626418.bglu_1g12050 1.87e-41 144.0 COG3772@1|root,COG3772@2|Bacteria,1N0ZQ@1224|Proteobacteria,2VVDM@28216|Betaproteobacteria,1K8XQ@119060|Burkholderiaceae 28216|Betaproteobacteria S lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_229064_2 1416009.V9VCX5_9CAUD 0.000597 46.2 4QEG2@10239|Viruses,4QVSD@35237|dsDNA viruses no RNA stage,4QRJ9@28883|Caudovirales,4QP0R@10744|Podoviridae 10744|Podoviridae S exonuclease activity - - - - - - - - - - - - - k59_80589_1 1385658.U5KPZ6_9VIRU 6.4e-146 431.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_148379_3 1385658.U5KPZ6_9VIRU 2.1e-188 546.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_172739_1 344747.PM8797T_09094 1.62e-30 125.0 COG3420@1|root,COG3420@2|Bacteria,2J2VK@203682|Planctomycetes 203682|Planctomycetes P Right handed beta helix region - - - - - - - - - - - - Beta_helix k59_63310_1 1392838.AWNM01000004_gene1802 9.24e-08 55.5 COG3740@1|root,COG3740@2|Bacteria,1NHKT@1224|Proteobacteria,2VV07@28216|Betaproteobacteria,3T8GV@506|Alcaligenaceae 28216|Betaproteobacteria S Caudovirus prohead serine protease - - - ko:K06904 - - - - ko00000 - - - Peptidase_S78 k59_63310_2 66875.JODY01000022_gene5854 0.000737 44.7 COG4695@1|root,COG4695@2|Bacteria,2I9PX@201174|Actinobacteria 201174|Actinobacteria S Phage portal protein - - - - - - - - - - - - Phage_portal k59_205641_1 105154.Q9MBU3_9VIRU 8.15e-13 70.1 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_223284_6 1121447.JONL01000001_gene569 7.22e-167 488.0 COG5362@1|root,COG5362@2|Bacteria,1PYY9@1224|Proteobacteria,435M3@68525|delta/epsilon subdivisions,2WZZT@28221|Deltaproteobacteria,2M981@213115|Desulfovibrionales 28221|Deltaproteobacteria S TIGRFAM Phage - - - - - - - - - - - - - k59_163413_1 511.JT27_18325 2.8e-40 155.0 COG0749@1|root,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2VJ57@28216|Betaproteobacteria,3T32Z@506|Alcaligenaceae 1224|Proteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity - - - - - - - - - - - - DNA_pol_A k59_139456_1 1453496.AT03_15205 3.27e-35 153.0 COG1196@1|root,COG5281@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5281@2|Bacteria,COG5283@2|Bacteria,1R47M@1224|Proteobacteria,1RYE6@1236|Gammaproteobacteria 1236|Gammaproteobacteria D COG5281, Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail,Phage_HK97_TLTM,Tape_meas_lam_C k59_7327_1 1379708.S5SYC3_9CIRC 9.75e-29 115.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_163417_4 1500893.JQNB01000001_gene3326 5.78e-14 68.9 COG0258@1|root,COG0258@2|Bacteria,1MYSI@1224|Proteobacteria,1SQ55@1236|Gammaproteobacteria 1236|Gammaproteobacteria L 5'-3' exonuclease, N-terminal resolvase-like domain - - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc_N k59_196231_1 402612.FP0810 2.65e-71 219.0 COG3023@1|root,COG3023@2|Bacteria,4NQ2J@976|Bacteroidetes,1I3X8@117743|Flavobacteriia,2NXVJ@237|Flavobacterium 976|Bacteroidetes V N-acetylmuramoyl-L-alanine amidase - - 3.5.1.28 ko:K01447 - - R04112 RC00064,RC00141 ko00000,ko01000 - - - Amidase_2 k59_123051_1 1126411.I1TEL3_9CIRC 1.7e-08 57.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_148391_1 1161927.I1TR10_9CAUD 1.19e-99 313.0 4QBG0@10239|Viruses,4QWYZ@35237|dsDNA viruses no RNA stage,4QSGM@28883|Caudovirales,4QK1H@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_63445_2 575615.HMPREF0670_00065 0.000205 47.4 COG0507@1|root,COG0507@2|Bacteria,4NDYK@976|Bacteroidetes,2FNT1@200643|Bacteroidia 976|Bacteroidetes L COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member - - - - - - - - - - - - AAA_30,UvrD_C_2 k59_254370_1 1158318.ATXC01000001_gene1026 2.73e-30 130.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2G3XK@200783|Aquificae 200783|Aquificae L 5'-3' exonuclease - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A k59_255208_1 1122201.AUAZ01000017_gene2947 7.4e-59 204.0 COG0749@1|root,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,465DD@72275|Alteromonadaceae 1236|Gammaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity - - - - - - - - - - - - DNA_pol_A k59_49706_1 1788454.A0A190WHE4_9CIRC 1.12e-12 68.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_49706_2 1618238.A0A0C5IB41_9CIRC 9.05e-18 87.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_115886_1 136084.Q9G0H4_9CAUD 1.68e-08 55.1 4QAUS@10239|Viruses,4QURX@35237|dsDNA viruses no RNA stage,4QQ2S@28883|Caudovirales,4QNNP@10744|Podoviridae 10744|Podoviridae S flavin adenine dinucleotide binding - - - - - - - - - - - - - k59_115886_3 113395.AXAI01000008_gene1007 8.58e-33 119.0 2EU9D@1|root,33MRT@2|Bacteria,1NCDT@1224|Proteobacteria,2UHVU@28211|Alphaproteobacteria,3K234@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_132137_1 640081.Dsui_0207 1.01e-18 84.7 COG0791@1|root,COG0791@2|Bacteria,1PW5U@1224|Proteobacteria,2VV27@28216|Betaproteobacteria,2KZ83@206389|Rhodocyclales 206389|Rhodocyclales M NLP P60 protein - - - - - - - - - - - - - k59_97517_2 1609634.A0A0C5AFV4_9VIRU 8.56e-169 492.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_156859_1 1158150.KB906242_gene227 1.3e-89 289.0 28IA2@1|root,2Z8CQ@2|Bacteria,1PQM2@1224|Proteobacteria,1SN3W@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_14807_1 420324.KI911970_gene1455 2.56e-53 176.0 2ATMD@1|root,31J5V@2|Bacteria,1RH31@1224|Proteobacteria,2UBNT@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Tail tubular protein - - - - - - - - - - - - Tube k59_197307_2 1095743.HMPREF1054_1282 1.76e-21 87.4 2D1MV@1|root,32TAZ@2|Bacteria,1N45A@1224|Proteobacteria,1S954@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage protein (N4 Gp49/phage Sf6 gene 66) family - - - - - - - - - - - - DUF2829,Phage_gp49_66 k59_206631_3 910314.HMPREF9220_0734 3.95e-16 82.0 COG0749@1|root,COG0749@2|Bacteria 2|Bacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity - - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - DNA_pol_A,RNase_H_2 k59_115974_1 691965.D4P7E6_9CAUD 4.13e-157 518.0 4QAK6@10239|Viruses,4R01K@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_115974_2 478749.BRYFOR_08514 4.06e-27 102.0 2ARVA@1|root,31H70@2|Bacteria,1V7JT@1239|Firmicutes,24JPE@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - HK97-gp10_like k59_173985_6 105154.Q9MBU6_9VIRU 2.74e-207 594.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_206716_2 742733.HMPREF9469_05030 4.46e-40 149.0 28JK5@1|root,2Z9D1@2|Bacteria,1UJZJ@1239|Firmicutes,24D64@186801|Clostridia,222M5@1506553|Lachnoclostridium 186801|Clostridia S Caudovirus prohead serine protease - - - - - - - - - - - - Peptidase_S78 k59_132268_2 1007105.PT7_P073 8.44e-12 64.3 2CH99@1|root,32S5M@2|Bacteria,1N2GH@1224|Proteobacteria,2W6BX@28216|Betaproteobacteria 28216|Betaproteobacteria S Recombination enhancement, RecA-dependent nuclease - - - - - - - - - - - - RecA_dep_nuc k59_181559_1 1415780.JPOG01000001_gene1744 1.25e-12 72.8 COG0454@1|root,COG0827@1|root,COG1040@1|root,COG3087@1|root,COG0456@2|Bacteria,COG0827@2|Bacteria,COG1040@2|Bacteria,COG3087@2|Bacteria,1PI1K@1224|Proteobacteria,1T6BU@1236|Gammaproteobacteria,1XB7I@135614|Xanthomonadales 135614|Xanthomonadales D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - - - - - - - - - - - k59_39890_1 1123508.JH636448_gene7696 0.000133 47.8 2DIG9@1|root,3036R@2|Bacteria 2|Bacteria L YqaJ-like viral recombinase domain - - 3.1.11.3 ko:K01143 - - - - ko00000,ko01000 - - - YqaJ k59_106533_2 272951.rsib_orf414 0.000159 50.4 COG0463@1|root,COG0463@2|Bacteria,1PVP4@1224|Proteobacteria,2U2KK@28211|Alphaproteobacteria,47GA4@766|Rickettsiales 766|Rickettsiales M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 k59_156961_2 1234888.K0A2J2_9VIRU 3.25e-85 271.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_265139_1 1379719.S5TMX6_9CIRC 1.12e-34 135.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_99385_1 323097.Nham_3850 4.84e-05 48.1 COG3210@1|root,COG3210@2|Bacteria,1PE7J@1224|Proteobacteria,2UZPP@28211|Alphaproteobacteria,3K4JU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria U domain, Protein - - - - - - - - - - - - - k59_248657_2 1126885.I3VYU7_9CAUD 2.47e-05 55.1 4QAK6@10239|Viruses,4QVAN@35237|dsDNA viruses no RNA stage,4QQH3@28883|Caudovirales,4QKT9@10699|Siphoviridae 10699|Siphoviridae S chitin catabolic process - GO:0000270,GO:0001906,GO:0001907,GO:0005975,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009253,GO:0009605,GO:0009607,GO:0009617,GO:0016032,GO:0016052,GO:0019048,GO:0019058,GO:0019076,GO:0030203,GO:0031640,GO:0035821,GO:0035890,GO:0035891,GO:0039633,GO:0040011,GO:0043170,GO:0043207,GO:0044003,GO:0044004,GO:0044033,GO:0044035,GO:0044040,GO:0044041,GO:0044238,GO:0044278,GO:0044364,GO:0044403,GO:0044419,GO:0044659,GO:0044661,GO:0050896,GO:0051672,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0051818,GO:0051883,GO:0052126,GO:0052192,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - - - - - - - - - - - k59_265142_1 1692244.A0A0K1RLR5_9CIRC 5.69e-89 272.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_265143_2 1692249.A0A0K1RL40_9CIRC 3.68e-30 122.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_265147_1 1618248.A0A0C5IB82_9CIRC 4.84e-56 189.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_99436_1 1453501.JELR01000001_gene2516 2.15e-73 251.0 COG4733@1|root,COG4926@1|root,COG4733@2|Bacteria,COG4926@2|Bacteria,1R77Q@1224|Proteobacteria,1S1WT@1236|Gammaproteobacteria,469QU@72275|Alteromonadaceae 1236|Gammaproteobacteria S Fibronectin type 3 domain - - - - - - - - - - - - - k59_90325_2 1609634.A0A0C5AFV4_9VIRU 1.37e-83 265.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_265148_1 1986029.Q9MBM8_9VIRU 1.13e-85 271.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_265148_2 105154.Q9MBU3_9VIRU 8.34e-16 79.3 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_265148_4 145579.REP_BPPHM 1.3e-25 111.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_265148_6 186617.M9M8L2_9VIRU 6.49e-75 244.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_99455_1 1380394.JADL01000004_gene6135 1.57e-41 149.0 COG5565@1|root,COG5565@2|Bacteria,1R6R3@1224|Proteobacteria,2U1P9@28211|Alphaproteobacteria,2JX6C@204441|Rhodospirillales 204441|Rhodospirillales S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_99455_2 484895.A9J745_BPLUZ 5.88e-15 75.1 4QAUF@10239|Viruses,4QQIV@28883|Caudovirales,4QNZ6@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - ## 7655 queries scanned ## Total time (seconds): 76.68932843208313 ## Rate: 99.82 q/s